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Search of human proteins with 50511947
BLASTP 2.2.11 [Jun-05-2005]
Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer,
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997),
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs", Nucleic Acids Res. 25:3389-3402.
Query= gi|50511947 cajalin 2 isoform b [Homo sapiens]
(510 letters)
Database: hs.faa
37,866 sequences; 18,247,518 total letters
Searching..................................................done
Score E
Sequences producing significant alignments: (bits) Value
gi|50511947 cajalin 2 isoform b [Homo sapiens] 1051 0.0
gi|50511945 cajalin 2 isoform a [Homo sapiens] 842 0.0
gi|140161500 ankyrin repeat and sterile alpha motif domain conta... 503 e-142
gi|10047134 cajalin 2 isoform c [Homo sapiens] 416 e-116
gi|7705318 GULP, engulfment adaptor PTB domain containing 1 [Hom... 95 2e-19
gi|217416350 cask-interacting protein 2 isoform b [Homo sapiens] 62 9e-10
gi|217416347 cask-interacting protein 2 isoform a [Homo sapiens] 62 9e-10
gi|10863899 numb homolog (Drosophila)-like [Homo sapiens] 60 4e-09
gi|221625422 ephrin receptor EphA5 isoform b precursor [Homo sap... 60 6e-09
gi|221625401 ephrin receptor EphA5 isoform a precursor [Homo sap... 60 6e-09
gi|18079216 CASK interacting protein 1 [Homo sapiens] 60 6e-09
gi|54144629 numb homolog isoform 4 [Homo sapiens] 59 1e-08
gi|20070356 numb homolog isoform 3 [Homo sapiens] 59 1e-08
gi|132626790 low density lipoprotein receptor adaptor protein 1 ... 58 2e-08
gi|31317301 nitric oxide synthase 1 (neuronal) adaptor protein i... 57 5e-08
gi|54144627 numb homolog isoform 2 [Homo sapiens] 57 5e-08
gi|54144625 numb homolog isoform 1 [Homo sapiens] 57 5e-08
gi|194239668 SHC (Src homology 2 domain containing) transforming... 52 1e-06
gi|194239664 SHC (Src homology 2 domain containing) transforming... 52 1e-06
gi|194239662 SHC (Src homology 2 domain containing) transforming... 52 1e-06
gi|32261324 SHC (Src homology 2 domain containing) transforming ... 52 1e-06
gi|224586793 src homology 2 domain-containing transforming prote... 52 2e-06
gi|33350928 disabled homolog 1 [Homo sapiens] 51 2e-06
gi|145312251 EPH receptor A6 isoform a [Homo sapiens] 51 2e-06
gi|17975768 ephrin receptor EphB3 precursor [Homo sapiens] 51 3e-06
gi|222446609 rai-like protein [Homo sapiens] 49 8e-06
gi|148491082 disabled homolog 2 [Homo sapiens] 49 1e-05
gi|32528301 EPH receptor B4 precursor [Homo sapiens] 48 2e-05
gi|10140845 ephrin receptor EphA8 isoform 1 precursor [Homo sapi... 47 4e-05
gi|71834346 sterile alpha motif domain containing 5 [Homo sapiens] 47 4e-05
>gi|50511947 cajalin 2 isoform b [Homo sapiens]
Length = 510
Score = 1051 bits (2717), Expect = 0.0
Identities = 510/510 (100%), Positives = 510/510 (100%)
Query: 1 MMWQCHLSAQDYRYYPVDGYSLLKRFPLHPLTGPRCPVQTVGQWLESIGLPQYENHLMAN 60
MMWQCHLSAQDYRYYPVDGYSLLKRFPLHPLTGPRCPVQTVGQWLESIGLPQYENHLMAN
Sbjct: 1 MMWQCHLSAQDYRYYPVDGYSLLKRFPLHPLTGPRCPVQTVGQWLESIGLPQYENHLMAN 60
Query: 61 GFDNVQFMGSNVMEDQDLLEIGILNSGHRQRILQAIQLLPKMRPIGHDGYHPTSVAEWLD 120
GFDNVQFMGSNVMEDQDLLEIGILNSGHRQRILQAIQLLPKMRPIGHDGYHPTSVAEWLD
Sbjct: 61 GFDNVQFMGSNVMEDQDLLEIGILNSGHRQRILQAIQLLPKMRPIGHDGYHPTSVAEWLD 120
Query: 121 SIELGDYTKAFLINGYTSMDLLKKIWEVELINVLKINLIGHRKRILASLGDRLHDDPPQK 180
SIELGDYTKAFLINGYTSMDLLKKIWEVELINVLKINLIGHRKRILASLGDRLHDDPPQK
Sbjct: 121 SIELGDYTKAFLINGYTSMDLLKKIWEVELINVLKINLIGHRKRILASLGDRLHDDPPQK 180
Query: 181 PPRSITLREPSGNHTPPQLSPSLSQSTYTTGGSLDVPHIIMQGDARRRRNENYFDDIPRS 240
PPRSITLREPSGNHTPPQLSPSLSQSTYTTGGSLDVPHIIMQGDARRRRNENYFDDIPRS
Sbjct: 181 PPRSITLREPSGNHTPPQLSPSLSQSTYTTGGSLDVPHIIMQGDARRRRNENYFDDIPRS 240
Query: 241 KLERQMAQSSVCEIWTNQNAGFPFSAIHQVHNTGDWGEPSITLRPPNEATASTPVQYWQH 300
KLERQMAQSSVCEIWTNQNAGFPFSAIHQVHNTGDWGEPSITLRPPNEATASTPVQYWQH
Sbjct: 241 KLERQMAQSSVCEIWTNQNAGFPFSAIHQVHNTGDWGEPSITLRPPNEATASTPVQYWQH 300
Query: 301 HPEKLIFQSCDYKAFYLGSMLIKELRGTESTQDACAKMRANCQKSTEQMKKVPTIILSVS 360
HPEKLIFQSCDYKAFYLGSMLIKELRGTESTQDACAKMRANCQKSTEQMKKVPTIILSVS
Sbjct: 301 HPEKLIFQSCDYKAFYLGSMLIKELRGTESTQDACAKMRANCQKSTEQMKKVPTIILSVS 360
Query: 361 YKGVKFIDATNKNIIAEHEIRNISCAAQDPEDLSTFAYITKDLKSNHHYCHVFTAFDVNL 420
YKGVKFIDATNKNIIAEHEIRNISCAAQDPEDLSTFAYITKDLKSNHHYCHVFTAFDVNL
Sbjct: 361 YKGVKFIDATNKNIIAEHEIRNISCAAQDPEDLSTFAYITKDLKSNHHYCHVFTAFDVNL 420
Query: 421 AYEIILTLGQAFEVAYQLALQARKGGHSSTLPESFENKPSKPIPKPRVSIRKSVQIDPSE 480
AYEIILTLGQAFEVAYQLALQARKGGHSSTLPESFENKPSKPIPKPRVSIRKSVQIDPSE
Sbjct: 421 AYEIILTLGQAFEVAYQLALQARKGGHSSTLPESFENKPSKPIPKPRVSIRKSVQIDPSE 480
Query: 481 QKTLANLPWIVEPGQEAKRGINTKYETTIF 510
QKTLANLPWIVEPGQEAKRGINTKYETTIF
Sbjct: 481 QKTLANLPWIVEPGQEAKRGINTKYETTIF 510
>gi|50511945 cajalin 2 isoform a [Homo sapiens]
Length = 1248
Score = 842 bits (2175), Expect = 0.0
Identities = 422/460 (91%), Positives = 425/460 (92%), Gaps = 32/460 (6%)
Query: 32 TGPRCPVQTVGQWLESIGLPQYENHLMANGFDNVQFMGSNVMEDQDLLEIGILNSGHRQR 91
T PRCPVQTVGQWLESIGLPQYENHLMANGFDNVQFMGSNVMEDQDLLEIGILNSGHRQR
Sbjct: 806 TRPRCPVQTVGQWLESIGLPQYENHLMANGFDNVQFMGSNVMEDQDLLEIGILNSGHRQR 865
Query: 92 ILQAIQLLPKMRPIGHDGYHPTSVAEWLDSIELGDYTKAFLINGYTSMDLLKKIWEVELI 151
ILQAIQLLPKMRPIGHDGYHPTSVAEWLDSIELGDYTKAFLINGYTSMDLLKKIWEVELI
Sbjct: 866 ILQAIQLLPKMRPIGHDGYHPTSVAEWLDSIELGDYTKAFLINGYTSMDLLKKIWEVELI 925
Query: 152 NVLKINLIGHRKRILASLGDRLHDDPPQKPPRSITLREPSGNHTPPQLSPSLSQSTYTTG 211
NVLKINLIGHRKRILASLGDRLHDDPPQKPPRSITLREPSGNHTPPQLSPSLSQSTYTTG
Sbjct: 926 NVLKINLIGHRKRILASLGDRLHDDPPQKPPRSITLREPSGNHTPPQLSPSLSQSTYTTG 985
Query: 212 GSLDVPHIIMQGDARRRRNENYFDDIPRSKLERQMAQSSVCEIWTNQNAGFPFSAIHQVH 271
GSLDVPHIIMQGDARRRRNENYFDDIPRSKLERQMAQ
Sbjct: 986 GSLDVPHIIMQGDARRRRNENYFDDIPRSKLERQMAQ----------------------- 1022
Query: 272 NTGDWGEPSITLRPPNEATASTPVQYWQHHPEKLIFQSCDYKAFYLGSMLIKELRGTEST 331
TGDWGEPSITLRPPNEATASTPVQYWQHHPEKLIFQSCDYKAFYLGSMLIKELRGTEST
Sbjct: 1023 -TGDWGEPSITLRPPNEATASTPVQYWQHHPEKLIFQSCDYKAFYLGSMLIKELRGTEST 1081
Query: 332 QDACAKMRANCQKSTEQMKKVPTIILSVSYKGVKFIDATNKNIIAEHEIRNISCAAQDPE 391
QDACAKMRANCQKSTEQMKKVPTIILSVSYKGVKFIDATNKNIIAEHEIRNISCAAQDPE
Sbjct: 1082 QDACAKMRANCQKSTEQMKKVPTIILSVSYKGVKFIDATNKNIIAEHEIRNISCAAQDPE 1141
Query: 392 DLSTFAYITKDLKSNHHYCHVFTAFDVNLAYEIILTLGQAFEVAYQLALQARKGGHSSTL 451
DLSTFAYITKDLKSNHHYCHVFTAFDVNLAYEIILTLGQAFEVAYQLALQARKGGHSSTL
Sbjct: 1142 DLSTFAYITKDLKSNHHYCHVFTAFDVNLAYEIILTLGQAFEVAYQLALQARKGGHSSTL 1201
Query: 452 PESFENKPSKPIPKPRVSIRKSVQI--------DPSEQKT 483
PESFENKPSKPIPKPRVSIRKSV + +PSE+ T
Sbjct: 1202 PESFENKPSKPIPKPRVSIRKSVDLLHASHTGQEPSERHT 1241
>gi|140161500 ankyrin repeat and sterile alpha motif domain containing
1 [Homo sapiens]
Length = 1134
Score = 503 bits (1294), Expect = e-142
Identities = 264/477 (55%), Positives = 337/477 (70%), Gaps = 38/477 (7%)
Query: 31 LTGPRCPVQTVGQWLESIGLPQYENHLMANGFDNVQFMGSNVMEDQDLLEIGILNSGHRQ 90
++G R Q+VG+WLESIGL QYE+ L+ NGFD+V F+GSNVME+QDL +IGI + HR+
Sbjct: 691 ISGLRTLEQSVGEWLESIGLQQYESKLLLNGFDDVHFLGSNVMEEQDLRDIGISDPQHRR 750
Query: 91 RILQAIQLLPKMRPIGHDGYHPTSVAEWLDSIELGDYTKAFLINGYTSMDLLKKIWEVEL 150
++LQA + LPK++ +G+DG P SV WLDS+ L DY +FL +GY+S+D +K +WE+EL
Sbjct: 751 KLLQAARSLPKVKALGYDGNSPPSVPSWLDSLGLQDYVHSFLSSGYSSIDTVKNLWELEL 810
Query: 151 INVLKINLIGHRKRILASLGDRLHDDPPQKPPRSITLREPSGNHTPPQLSPSLSQSTYTT 210
+NVLK+ L+GHRKRI+ASL DR +++PPQKPPR LR Q S LSQ+ T
Sbjct: 811 VNVLKVQLLGHRKRIIASLADRPYEEPPQKPPRFSQLR---CQDLLSQTSSPLSQNDSCT 867
Query: 211 GGSLDVPHIIMQGDARRRRNENYFDDIPRSKLERQMAQSSVCEIWTNQNAGFPFSAIHQV 270
G S D+ ++ GD RRR+++ D S+ ER Q
Sbjct: 868 GRSADL--LLPPGDTGRRRHDSLHDPAAPSRAERFRIQE--------------------- 904
Query: 271 HNTGDWGEPSITLRPPNEATASTPVQYWQHHPEKLIFQSCDYKAFYLGSMLIKELRGTES 330
+ E +TLRPP+ A PVQ WQH PEKLIF+SC Y+A YLGSMLIK+LRGTES
Sbjct: 905 ----EHREAKLTLRPPSLAAPYAPVQSWQHQPEKLIFESCGYEANYLGSMLIKDLRGTES 960
Query: 331 TQDACAKMRANCQKSTEQMKKVPTIILSVSYKGVKFIDATNKNIIAEHEIRNISCAAQDP 390
TQDACAKMR KSTE MKK+PTIILS++YKGVKFIDA+NKN+IAEHEIRNISCAAQDP
Sbjct: 961 TQDACAKMR----KSTEHMKKIPTIILSITYKGVKFIDASNKNVIAEHEIRNISCAAQDP 1016
Query: 391 EDLSTFAYITKDLKSNHHYCHVFTAFDVNLAYEIILTLGQAFEVAYQLALQARKG-GHSS 449
EDL TFAYITKDL+++HHYCHVF+ DVNL YEIILTLGQAFEVAYQLALQA+K +
Sbjct: 1017 EDLCTFAYITKDLQTSHHYCHVFSTVDVNLTYEIILTLGQAFEVAYQLALQAQKSRATGA 1076
Query: 450 TLPESFENKPSKPIPKPRVSIRKSVQIDP---SEQKTLANLPWIVEPGQEAKRGINT 503
+ E E K SKP+PKPRV +RKS P + ++ A++ W+V+P ++KR ++T
Sbjct: 1077 SAAEMIETKSSKPVPKPRVGVRKSALEPPDMDQDAQSHASVSWVVDPKPDSKRSLST 1133
>gi|10047134 cajalin 2 isoform c [Homo sapiens]
Length = 414
Score = 416 bits (1069), Expect = e-116
Identities = 206/219 (94%), Positives = 209/219 (95%), Gaps = 8/219 (3%)
Query: 273 TGDWGEPSITLRPPNEATASTPVQYWQHHPEKLIFQSCDYKAFYLGSMLIKELRGTESTQ 332
TGDWGEPSITLRPPNEATASTPVQYWQHHPEKLIFQSCDYKAFYLGSMLIKELRGTESTQ
Sbjct: 189 TGDWGEPSITLRPPNEATASTPVQYWQHHPEKLIFQSCDYKAFYLGSMLIKELRGTESTQ 248
Query: 333 DACAKMRANCQKSTEQMKKVPTIILSVSYKGVKFIDATNKNIIAEHEIRNISCAAQDPED 392
DACAKMRANCQKSTEQMKKVPTIILSVSYKGVKFIDATNKNIIAEHEIRNISCAAQDPED
Sbjct: 249 DACAKMRANCQKSTEQMKKVPTIILSVSYKGVKFIDATNKNIIAEHEIRNISCAAQDPED 308
Query: 393 LSTFAYITKDLKSNHHYCHVFTAFDVNLAYEIILTLGQAFEVAYQLALQARKGGHSSTLP 452
LSTFAYITKDLKSNHHYCHVFTAFDVNLAYEIILTLGQAFEVAYQLALQARKGGHSSTLP
Sbjct: 309 LSTFAYITKDLKSNHHYCHVFTAFDVNLAYEIILTLGQAFEVAYQLALQARKGGHSSTLP 368
Query: 453 ESFENKPSKPIPKPRVSIRKSVQI--------DPSEQKT 483
ESFENKPSKPIPKPRVSIRKSV + +PSE+ T
Sbjct: 369 ESFENKPSKPIPKPRVSIRKSVDLLHASHTGQEPSERHT 407
Score = 396 bits (1018), Expect = e-110
Identities = 193/202 (95%), Positives = 193/202 (95%), Gaps = 5/202 (2%)
Query: 1 MMWQCHLSAQDYRYYPVDGYSLLKRFPLHPLTGPRCPVQTVGQWLESIGLPQYENHLMAN 60
MMWQCHLSAQDYRYYPVDGYSLLKRFPLHPLTGPRCPVQTVGQWLESIGLPQYENHLMAN
Sbjct: 1 MMWQCHLSAQDYRYYPVDGYSLLKRFPLHPLTGPRCPVQTVGQWLESIGLPQYENHLMAN 60
Query: 61 GFDNVQFMGSNVMEDQDLLEIGILNSGHRQRILQAIQLLPKMRPIGHDGYHPTSVAEWLD 120
GFDNVQFMGSNVMEDQDLLEIGILNSGHRQRILQAIQLLPKMRPIGHDGYHPTSVAEWLD
Sbjct: 61 GFDNVQFMGSNVMEDQDLLEIGILNSGHRQRILQAIQLLPKMRPIGHDGYHPTSVAEWLD 120
Query: 121 SIELGDYTKAFLINGYTSMDLLKKIWEVELINVLKINLIGHRKRILASLGDRLHDDPPQK 180
SIELGDYTKAFLINGYTSMDLLKKIWEVELINVLKINLIGHRKRILASLGDRLHDDPPQK
Sbjct: 121 SIELGDYTKAFLINGYTSMDLLKKIWEVELINVLKINLIGHRKRILASLGDRLHDDPPQK 180
Query: 181 PPRSITLR-----EPSGNHTPP 197
PPRSITLR EPS PP
Sbjct: 181 PPRSITLRTGDWGEPSITLRPP 202
>gi|7705318 GULP, engulfment adaptor PTB domain containing 1 [Homo
sapiens]
Length = 304
Score = 94.7 bits (234), Expect = 2e-19
Identities = 53/156 (33%), Positives = 83/156 (53%), Gaps = 2/156 (1%)
Query: 287 NEATASTPVQYWQHHPEKLIFQSCDYKAFYLGSMLIKELRGTESTQDACAKMRANCQKST 346
N A + + W H PE L Y A +LGS +++ +GTE +DA K++
Sbjct: 2 NRAFSRKKDKTWMHTPEALSKHFIPYNAKFLGSTEVEQPKGTEVVRDAVRKLKFARHIKK 61
Query: 347 EQMKKVPTIILSVSYKGVKFIDATNKNIIAEHEIRNISCAAQDPEDLSTFAYITKDLKSN 406
+ +K+P + L +S GVK ++ K + ++ IS A D D F +I KD +SN
Sbjct: 62 SEGQKIPKVELQISIYGVKILEPKTKEVQHNCQLHRISFCADDKTDKRIFTFICKDSESN 121
Query: 407 HHYCHVFTAFDVNLAYEIILTLGQAFEVAYQLALQA 442
H C+VF + A EI LT+GQAF++AY+ L++
Sbjct: 122 KHLCYVFDS--EKCAEEITLTIGQAFDLAYRKFLES 155
>gi|217416350 cask-interacting protein 2 isoform b [Homo sapiens]
Length = 1120
Score = 62.4 bits (150), Expect = 9e-10
Identities = 39/129 (30%), Positives = 63/129 (48%), Gaps = 8/129 (6%)
Query: 39 QTVGQWLESIGLPQYENHLMANGFDNVQFMGSNVMEDQDLLEIGILNSGHRQRILQAIQL 98
Q + WL L Y H + G+D + M +DL IG+ GHR++I I
Sbjct: 410 QAIHNWLSEFQLEGYTAHFLQAGYDVPTI---SRMTPEDLTAIGVTKPGHRKKIASEIAQ 466
Query: 99 LPKMRPIGHDGYHPTSVAEWLDSIELGDYTKAFLINGYTSMDLLKKI-WEVELINVLKIN 157
L + Y PT + EWL ++ L Y K + +GY SM L+ + WE + + +N
Sbjct: 467 LSIAEWL--PSYIPTDLLEWLCALGLPQYHKQLVSSGYDSMGLVADLTWEE--LQEIGVN 522
Query: 158 LIGHRKRIL 166
+GH+K+++
Sbjct: 523 KLGHQKKLM 531
Score = 45.4 bits (106), Expect = 1e-04
Identities = 19/61 (31%), Positives = 40/61 (65%), Gaps = 2/61 (3%)
Query: 43 QWLESIGLPQYENHLMANGFDNVQFMGSNVMEDQDLLEIGILNSGHRQRILQAIQLLPKM 102
+WL ++GLPQY L+++G+D++ + E+ L EIG+ GH+++++ ++ L ++
Sbjct: 483 EWLCALGLPQYHKQLVSSGYDSMGLVADLTWEE--LQEIGVNKLGHQKKLMLGVKRLAEL 540
Query: 103 R 103
R
Sbjct: 541 R 541
>gi|217416347 cask-interacting protein 2 isoform a [Homo sapiens]
Length = 1202
Score = 62.4 bits (150), Expect = 9e-10
Identities = 39/129 (30%), Positives = 63/129 (48%), Gaps = 8/129 (6%)
Query: 39 QTVGQWLESIGLPQYENHLMANGFDNVQFMGSNVMEDQDLLEIGILNSGHRQRILQAIQL 98
Q + WL L Y H + G+D + M +DL IG+ GHR++I I
Sbjct: 492 QAIHNWLSEFQLEGYTAHFLQAGYDVPTI---SRMTPEDLTAIGVTKPGHRKKIASEIAQ 548
Query: 99 LPKMRPIGHDGYHPTSVAEWLDSIELGDYTKAFLINGYTSMDLLKKI-WEVELINVLKIN 157
L + Y PT + EWL ++ L Y K + +GY SM L+ + WE + + +N
Sbjct: 549 LSIAEWL--PSYIPTDLLEWLCALGLPQYHKQLVSSGYDSMGLVADLTWEE--LQEIGVN 604
Query: 158 LIGHRKRIL 166
+GH+K+++
Sbjct: 605 KLGHQKKLM 613
Score = 45.4 bits (106), Expect = 1e-04
Identities = 19/61 (31%), Positives = 40/61 (65%), Gaps = 2/61 (3%)
Query: 43 QWLESIGLPQYENHLMANGFDNVQFMGSNVMEDQDLLEIGILNSGHRQRILQAIQLLPKM 102
+WL ++GLPQY L+++G+D++ + E+ L EIG+ GH+++++ ++ L ++
Sbjct: 565 EWLCALGLPQYHKQLVSSGYDSMGLVADLTWEE--LQEIGVNKLGHQKKLMLGVKRLAEL 622
Query: 103 R 103
R
Sbjct: 623 R 623
>gi|10863899 numb homolog (Drosophila)-like [Homo sapiens]
Length = 609
Score = 60.5 bits (145), Expect = 4e-09
Identities = 38/132 (28%), Positives = 63/132 (47%), Gaps = 8/132 (6%)
Query: 284 RPPNEATASTPVQYWQHHPEKLIFQSCDYKAFYLGSMLIKELRGTESTQDACAKMRANCQ 343
+P AS P Q WQ + + +C + YLG + ++E RG +DA K++A +
Sbjct: 53 KPAYVPEASRPHQ-WQADEDAVRKGTCSFPVRYLGHVEVEESRGMHVCEDAVKKLKAMGR 111
Query: 344 KSTEQMKKVPTIILSVSYKGVKFIDATNKNIIAEHEIRNISCAAQDPEDLSTFAYITKDL 403
KS + +L VS G++ +D K+++ + I +S A D F+YI +D
Sbjct: 112 KSVKS-------VLWVSADGLRVVDDKTKDLLVDQTIEKVSFCAPDRNLDKAFSYICRDG 164
Query: 404 KSNHHYCHVFTA 415
+ CH F A
Sbjct: 165 TTRRWICHCFLA 176
>gi|221625422 ephrin receptor EphA5 isoform b precursor [Homo sapiens]
Length = 1015
Score = 59.7 bits (143), Expect = 6e-09
Identities = 30/72 (41%), Positives = 49/72 (68%), Gaps = 3/72 (4%)
Query: 98 LLPKMRPIGHDGYHPTSVAEWLDSIELGDYTKAFLINGYTSMDLLKKIWEVELINVLKIN 157
LL + P+G Y SV EWL++I++G YT+ F+ NGY+SMD + ++ +E + L +
Sbjct: 933 LLAEHSPLGSGAYR--SVGEWLEAIKMGRYTEIFMENGYSSMDAVAQV-TLEDLRRLGVT 989
Query: 158 LIGHRKRILASL 169
L+GH+K+I+ SL
Sbjct: 990 LVGHQKKIMNSL 1001
Score = 42.0 bits (97), Expect = 0.001
Identities = 18/59 (30%), Positives = 37/59 (62%), Gaps = 2/59 (3%)
Query: 39 QTVGQWLESIGLPQYENHLMANGFDNVQFMGSNVMEDQDLLEIGILNSGHRQRILQAIQ 97
++VG+WLE+I + +Y M NG+ ++ + +E DL +G+ GH+++I+ ++Q
Sbjct: 946 RSVGEWLEAIKMGRYTEIFMENGYSSMDAVAQVTLE--DLRRLGVTLVGHQKKIMNSLQ 1002
>gi|221625401 ephrin receptor EphA5 isoform a precursor [Homo sapiens]
Length = 1037
Score = 59.7 bits (143), Expect = 6e-09
Identities = 30/72 (41%), Positives = 49/72 (68%), Gaps = 3/72 (4%)
Query: 98 LLPKMRPIGHDGYHPTSVAEWLDSIELGDYTKAFLINGYTSMDLLKKIWEVELINVLKIN 157
LL + P+G Y SV EWL++I++G YT+ F+ NGY+SMD + ++ +E + L +
Sbjct: 955 LLAEHSPLGSGAYR--SVGEWLEAIKMGRYTEIFMENGYSSMDAVAQV-TLEDLRRLGVT 1011
Query: 158 LIGHRKRILASL 169
L+GH+K+I+ SL
Sbjct: 1012 LVGHQKKIMNSL 1023
Score = 42.0 bits (97), Expect = 0.001
Identities = 18/59 (30%), Positives = 37/59 (62%), Gaps = 2/59 (3%)
Query: 39 QTVGQWLESIGLPQYENHLMANGFDNVQFMGSNVMEDQDLLEIGILNSGHRQRILQAIQ 97
++VG+WLE+I + +Y M NG+ ++ + +E DL +G+ GH+++I+ ++Q
Sbjct: 968 RSVGEWLEAIKMGRYTEIFMENGYSSMDAVAQVTLE--DLRRLGVTLVGHQKKIMNSLQ 1024
>gi|18079216 CASK interacting protein 1 [Homo sapiens]
Length = 1431
Score = 59.7 bits (143), Expect = 6e-09
Identities = 40/134 (29%), Positives = 67/134 (50%), Gaps = 12/134 (8%)
Query: 39 QTVGQWLESIGLPQYENHLMANGFDNVQFMGSNVMEDQDLLEIGILNSGHRQRILQAIQL 98
+ V QWL + L Y + ++ G+D + M +DL IG+ GHR++I I
Sbjct: 475 EAVSQWLTAFQLQLYAPNFISAGYDLPTI---SRMTPEDLTAIGVTKPGHRKKIAAEISG 531
Query: 99 L--PKMRPIGHDGYHPTSVAEWLDSIELGDYTKAFLINGYTSMDLLKKI-WEVELINVLK 155
L P P + P ++A WL I L Y K + NGY ++D + I WE + +
Sbjct: 532 LSIPDWLP----EHKPANLAVWLSMIGLAQYYKVLVDNGYENIDFITDITWED--LQEIG 585
Query: 156 INLIGHRKRILASL 169
I +GH+K+++ ++
Sbjct: 586 ITKLGHQKKLMLAV 599
Score = 48.5 bits (114), Expect = 1e-05
Identities = 24/67 (35%), Positives = 40/67 (59%), Gaps = 2/67 (2%)
Query: 44 WLESIGLPQYENHLMANGFDNVQFMGSNVMEDQDLLEIGILNSGHRQRILQAIQLLPKMR 103
WL IGL QY L+ NG++N+ F+ E DL EIGI GH+++++ A++ L +++
Sbjct: 549 WLSMIGLAQYYKVLVDNGYENIDFITDITWE--DLQEIGITKLGHQKKLMLAVRKLAELQ 606
Query: 104 PIGHDGY 110
+ Y
Sbjct: 607 KAEYAKY 613
Score = 32.0 bits (71), Expect = 1.4
Identities = 22/89 (24%), Positives = 41/89 (46%), Gaps = 3/89 (3%)
Query: 100 PKMRPIGHDGYHPTSVAEWLDSIELGDYTKAFLINGYTSMDLLKKIWEVELINVLKINLI 159
PK +G +V++WL + +L Y F+ GY + + E + + +
Sbjct: 462 PKKLEPASEGKSSEAVSQWLTAFQLQLYAPNFISAGYDLPTISR--MTPEDLTAIGVTKP 519
Query: 160 GHRKRILASL-GDRLHDDPPQKPPRSITL 187
GHRK+I A + G + D P+ P ++ +
Sbjct: 520 GHRKKIAAEISGLSIPDWLPEHKPANLAV 548
>gi|54144629 numb homolog isoform 4 [Homo sapiens]
Length = 592
Score = 58.9 bits (141), Expect = 1e-08
Identities = 37/125 (29%), Positives = 59/125 (47%), Gaps = 8/125 (6%)
Query: 291 ASTPVQYWQHHPEKLIFQSCDYKAFYLGSMLIKELRGTESTQDACAKMRANCQKSTEQMK 350
AS P Q WQ E + C + YLG + + E RG +DA +++A +K+ +
Sbjct: 19 ASRPHQ-WQTDEEGVRTGKCSFPVKYLGHVEVDESRGMHICEDAVKRLKATGKKAVKA-- 75
Query: 351 KVPTIILSVSYKGVKFIDATNKNIIAEHEIRNISCAAQDPEDLSTFAYITKDLKSNHHYC 410
+L VS G++ +D K++I + I +S A D F+YI +D + C
Sbjct: 76 -----VLWVSADGLRVVDEKTKDLIVDQTIEKVSFCAPDRNFDRAFSYICRDGTTRRWIC 130
Query: 411 HVFTA 415
H F A
Sbjct: 131 HCFMA 135
>gi|20070356 numb homolog isoform 3 [Homo sapiens]
Length = 640
Score = 58.9 bits (141), Expect = 1e-08
Identities = 37/125 (29%), Positives = 59/125 (47%), Gaps = 8/125 (6%)
Query: 291 ASTPVQYWQHHPEKLIFQSCDYKAFYLGSMLIKELRGTESTQDACAKMRANCQKSTEQMK 350
AS P Q WQ E + C + YLG + + E RG +DA +++A +K+ +
Sbjct: 19 ASRPHQ-WQTDEEGVRTGKCSFPVKYLGHVEVDESRGMHICEDAVKRLKATGKKAVKA-- 75
Query: 351 KVPTIILSVSYKGVKFIDATNKNIIAEHEIRNISCAAQDPEDLSTFAYITKDLKSNHHYC 410
+L VS G++ +D K++I + I +S A D F+YI +D + C
Sbjct: 76 -----VLWVSADGLRVVDEKTKDLIVDQTIEKVSFCAPDRNFDRAFSYICRDGTTRRWIC 130
Query: 411 HVFTA 415
H F A
Sbjct: 131 HCFMA 135
>gi|132626790 low density lipoprotein receptor adaptor protein 1
[Homo sapiens]
Length = 308
Score = 57.8 bits (138), Expect = 2e-08
Identities = 36/122 (29%), Positives = 59/122 (48%), Gaps = 3/122 (2%)
Query: 316 YLGSMLIKELRGTESTQDACAKMRANCQKSTEQMKKVPTIILSVSYKGVKFIDATNKNII 375
YLG L+++ +G E + A ++ A + S ++++KV L VS +G+ D +I
Sbjct: 52 YLGMTLVEQPKGEELSAAAIKRIVATAKASGKKLQKVT---LKVSPRGIILTDNLTNQLI 108
Query: 376 AEHEIRNISCAAQDPEDLSTFAYITKDLKSNHHYCHVFTAFDVNLAYEIILTLGQAFEVA 435
I IS D FAYI + + CH F +A + LT+ QAF+VA
Sbjct: 109 ENVSIYRISYCTADKMHDKVFAYIAQSQHNQSLECHAFLCTKRKMAQAVTLTVAQAFKVA 168
Query: 436 YQ 437
++
Sbjct: 169 FE 170
>gi|31317301 nitric oxide synthase 1 (neuronal) adaptor protein
isoform 1 [Homo sapiens]
Length = 506
Score = 56.6 bits (135), Expect = 5e-08
Identities = 44/157 (28%), Positives = 69/157 (43%), Gaps = 19/157 (12%)
Query: 301 HPEKLIFQSCDYKAFYLGSMLIKELRGTESTQDACAKMRANCQKSTEQMKKVPTIILSVS 360
H E ++A Y+GS+ + A ++R + + KKV + VS
Sbjct: 21 HNEDAFQHGICFEAKYVGSLDVPRPNSRVEIVAAMRRIRYEFKAKNIKKKKVS---IMVS 77
Query: 361 YKGVKFIDATNKNI----------------IAEHEIRNISCAAQDPEDLSTFAYITKDLK 404
GVK I K + + + I I + D +DL F+YI +D
Sbjct: 78 VDGVKVILKKKKKLLLLQKKEWTWDESKMLVMQDPIYRIFYVSHDSQDLKIFSYIARDGA 137
Query: 405 SNHHYCHVFTAFDVNLAYEIILTLGQAFEVAYQLALQ 441
SN C+VF + + A I+ T+GQAFEV ++L+LQ
Sbjct: 138 SNIFRCNVFKSKKKSQAMRIVRTVGQAFEVCHKLSLQ 174
>gi|54144627 numb homolog isoform 2 [Homo sapiens]
Length = 603
Score = 56.6 bits (135), Expect = 5e-08
Identities = 38/129 (29%), Positives = 59/129 (45%), Gaps = 5/129 (3%)
Query: 291 ASTPVQYWQHHPEKLIFQSCDYKAFYLGSMLIKELRGTESTQDACAKMRANCQKST---- 346
AS P Q WQ E + C + YLG + + E RG +DA +++A +
Sbjct: 19 ASRPHQ-WQTDEEGVRTGKCSFPVKYLGHVEVDESRGMHICEDAVKRLKAERKFFKGFFG 77
Query: 347 EQMKKVPTIILSVSYKGVKFIDATNKNIIAEHEIRNISCAAQDPEDLSTFAYITKDLKSN 406
+ KK +L VS G++ +D K++I + I +S A D F+YI +D +
Sbjct: 78 KTGKKAVKAVLWVSADGLRVVDEKTKDLIVDQTIEKVSFCAPDRNFDRAFSYICRDGTTR 137
Query: 407 HHYCHVFTA 415
CH F A
Sbjct: 138 RWICHCFMA 146
>gi|54144625 numb homolog isoform 1 [Homo sapiens]
Length = 651
Score = 56.6 bits (135), Expect = 5e-08
Identities = 38/129 (29%), Positives = 59/129 (45%), Gaps = 5/129 (3%)
Query: 291 ASTPVQYWQHHPEKLIFQSCDYKAFYLGSMLIKELRGTESTQDACAKMRANCQKST---- 346
AS P Q WQ E + C + YLG + + E RG +DA +++A +
Sbjct: 19 ASRPHQ-WQTDEEGVRTGKCSFPVKYLGHVEVDESRGMHICEDAVKRLKAERKFFKGFFG 77
Query: 347 EQMKKVPTIILSVSYKGVKFIDATNKNIIAEHEIRNISCAAQDPEDLSTFAYITKDLKSN 406
+ KK +L VS G++ +D K++I + I +S A D F+YI +D +
Sbjct: 78 KTGKKAVKAVLWVSADGLRVVDEKTKDLIVDQTIEKVSFCAPDRNFDRAFSYICRDGTTR 137
Query: 407 HHYCHVFTA 415
CH F A
Sbjct: 138 RWICHCFMA 146
>gi|194239668 SHC (Src homology 2 domain containing) transforming
protein 1 isoform 4 [Homo sapiens]
Length = 473
Score = 52.4 bits (124), Expect = 1e-06
Identities = 47/177 (26%), Positives = 83/177 (46%), Gaps = 32/177 (18%)
Query: 294 PVQYWQHHPEKLIFQSCDYKAFYLGSM-LIKELRG------TESTQDACA---------- 336
P + W H +K++ Y Y+G + +++ +R T+ T++A +
Sbjct: 34 PTRGWLHPNDKVMGPGVSYLVRYMGCVEVLQSMRALDFNTRTQVTREAISLVCEAVPGAK 93
Query: 337 ---KMRANCQK--------STEQMKKVPTIILSVSYKGVKFIDATNKNIIAEHEIRNISC 385
+ R C + S + +P I L+VS + + A K IIA H +++IS
Sbjct: 94 GATRRRKPCSRPLSSILGRSNLKFAGMP-ITLTVSTSSLNLMAADCKQIIANHHMQSISF 152
Query: 386 AA-QDPEDLSTFAYITKDLKSNHHYCHVFTAFDVNLAYEIILTLGQAFEVAYQLALQ 441
A+ DP+ AY+ KD N CH+ + LA ++I T+GQAFE+ ++ L+
Sbjct: 153 ASGGDPDTAEYVAYVAKD-PVNQRACHILECPE-GLAQDVISTIGQAFELRFKQYLR 207
>gi|194239664 SHC (Src homology 2 domain containing) transforming
protein 1 isoform 3 [Homo sapiens]
Length = 584
Score = 52.4 bits (124), Expect = 1e-06
Identities = 47/177 (26%), Positives = 83/177 (46%), Gaps = 32/177 (18%)
Query: 294 PVQYWQHHPEKLIFQSCDYKAFYLGSM-LIKELRG------TESTQDACA---------- 336
P + W H +K++ Y Y+G + +++ +R T+ T++A +
Sbjct: 144 PTRGWLHPNDKVMGPGVSYLVRYMGCVEVLQSMRALDFNTRTQVTREAISLVCEAVPGAK 203
Query: 337 ---KMRANCQK--------STEQMKKVPTIILSVSYKGVKFIDATNKNIIAEHEIRNISC 385
+ R C + S + +P I L+VS + + A K IIA H +++IS
Sbjct: 204 GATRRRKPCSRPLSSILGRSNLKFAGMP-ITLTVSTSSLNLMAADCKQIIANHHMQSISF 262
Query: 386 AA-QDPEDLSTFAYITKDLKSNHHYCHVFTAFDVNLAYEIILTLGQAFEVAYQLALQ 441
A+ DP+ AY+ KD N CH+ + LA ++I T+GQAFE+ ++ L+
Sbjct: 263 ASGGDPDTAEYVAYVAKD-PVNQRACHILECPE-GLAQDVISTIGQAFELRFKQYLR 317
>gi|194239662 SHC (Src homology 2 domain containing) transforming
protein 1 isoform 1 [Homo sapiens]
Length = 583
Score = 52.4 bits (124), Expect = 1e-06
Identities = 47/177 (26%), Positives = 83/177 (46%), Gaps = 32/177 (18%)
Query: 294 PVQYWQHHPEKLIFQSCDYKAFYLGSM-LIKELRG------TESTQDACA---------- 336
P + W H +K++ Y Y+G + +++ +R T+ T++A +
Sbjct: 144 PTRGWLHPNDKVMGPGVSYLVRYMGCVEVLQSMRALDFNTRTQVTREAISLVCEAVPGAK 203
Query: 337 ---KMRANCQK--------STEQMKKVPTIILSVSYKGVKFIDATNKNIIAEHEIRNISC 385
+ R C + S + +P I L+VS + + A K IIA H +++IS
Sbjct: 204 GATRRRKPCSRPLSSILGRSNLKFAGMP-ITLTVSTSSLNLMAADCKQIIANHHMQSISF 262
Query: 386 AA-QDPEDLSTFAYITKDLKSNHHYCHVFTAFDVNLAYEIILTLGQAFEVAYQLALQ 441
A+ DP+ AY+ KD N CH+ + LA ++I T+GQAFE+ ++ L+
Sbjct: 263 ASGGDPDTAEYVAYVAKD-PVNQRACHILECPE-GLAQDVISTIGQAFELRFKQYLR 317
>gi|32261324 SHC (Src homology 2 domain containing) transforming
protein 1 isoform 2 [Homo sapiens]
Length = 474
Score = 52.4 bits (124), Expect = 1e-06
Identities = 47/177 (26%), Positives = 83/177 (46%), Gaps = 32/177 (18%)
Query: 294 PVQYWQHHPEKLIFQSCDYKAFYLGSM-LIKELRG------TESTQDACA---------- 336
P + W H +K++ Y Y+G + +++ +R T+ T++A +
Sbjct: 34 PTRGWLHPNDKVMGPGVSYLVRYMGCVEVLQSMRALDFNTRTQVTREAISLVCEAVPGAK 93
Query: 337 ---KMRANCQK--------STEQMKKVPTIILSVSYKGVKFIDATNKNIIAEHEIRNISC 385
+ R C + S + +P I L+VS + + A K IIA H +++IS
Sbjct: 94 GATRRRKPCSRPLSSILGRSNLKFAGMP-ITLTVSTSSLNLMAADCKQIIANHHMQSISF 152
Query: 386 AA-QDPEDLSTFAYITKDLKSNHHYCHVFTAFDVNLAYEIILTLGQAFEVAYQLALQ 441
A+ DP+ AY+ KD N CH+ + LA ++I T+GQAFE+ ++ L+
Sbjct: 153 ASGGDPDTAEYVAYVAKD-PVNQRACHILECPE-GLAQDVISTIGQAFELRFKQYLR 207
>gi|224586793 src homology 2 domain-containing transforming protein
C3 [Homo sapiens]
Length = 594
Score = 51.6 bits (122), Expect = 2e-06
Identities = 32/89 (35%), Positives = 50/89 (56%), Gaps = 3/89 (3%)
Query: 354 TIILSVSYKGVKFIDATNKNIIAEHEIRNISCAA-QDPEDLSTFAYITKDLKSNHHYCHV 412
+I L++S + +K IIA H +R+IS A+ DP+ AY+ KD N CH+
Sbjct: 224 SISLTISTASLNLRTPDSKQIIANHHMRSISFASGGDPDTTDYVAYVAKD-PVNRRACHI 282
Query: 413 FTAFDVNLAYEIILTLGQAFEVAYQLALQ 441
D LA ++I ++GQAFE+ ++ LQ
Sbjct: 283 LECCD-GLAQDVIGSIGQAFELRFKQYLQ 310
>gi|33350928 disabled homolog 1 [Homo sapiens]
Length = 555
Score = 51.2 bits (121), Expect = 2e-06
Identities = 34/127 (26%), Positives = 58/127 (45%), Gaps = 4/127 (3%)
Query: 312 YKAFYLGSMLIKELRGTESTQDACAKMRANCQKSTEQMKKVPTIILSVSYKGVKFIDATN 371
YKA +G + RG + QD+ K++ + + + I L++S+ G+K D
Sbjct: 42 YKAKLIGIDEVSAARGDKLCQDSMMKLKGVVAGARSKGEHKQKIFLTISFGGIKIFDEKT 101
Query: 372 KNIIAEHEIRNISCAAQDPEDLSTFAYITKDLKSNHHYCHVFTAFDVNLAYEIILTLGQA 431
+ H + IS A+D D F Y+ + NH + + TA A +IL L
Sbjct: 102 GALQHHHAVHEISYIAKDITDHRAFGYVC-GKEGNHRFVAIKTA---QAAEPVILDLRDL 157
Query: 432 FEVAYQL 438
F++ Y+L
Sbjct: 158 FQLIYEL 164
>gi|145312251 EPH receptor A6 isoform a [Homo sapiens]
Length = 1130
Score = 51.2 bits (121), Expect = 2e-06
Identities = 32/87 (36%), Positives = 47/87 (54%), Gaps = 4/87 (4%)
Query: 27 PLHPLTGPRCPV-QTVGQWLESIGLPQYENHLMANGFDNVQFMGSNVMEDQDLLEIGILN 85
P P P P+ TVG WL+SI + QY+N+ +A GF + M D+ IG++
Sbjct: 1045 PESPGEVPEYPLFVTVGDWLDSIKMGQYKNNFVAAGFTTFDLISR--MSIDDIRRIGVIL 1102
Query: 86 SGHRQRILQAIQLLP-KMRPIGHDGYH 111
GH++RI+ +IQ L M I G+H
Sbjct: 1103 IGHQRRIVSSIQTLRLHMMHIQEKGFH 1129
Score = 49.7 bits (117), Expect = 6e-06
Identities = 24/62 (38%), Positives = 43/62 (69%), Gaps = 2/62 (3%)
Query: 114 SVAEWLDSIELGDYTKAFLINGYTSMDLLKKIWEVELINVLKINLIGHRKRILASLGD-R 172
+V +WLDSI++G Y F+ G+T+ DL+ ++ ++ I + + LIGH++RI++S+ R
Sbjct: 1059 TVGDWLDSIKMGQYKNNFVAAGFTTFDLISRM-SIDDIRRIGVILIGHQRRIVSSIQTLR 1117
Query: 173 LH 174
LH
Sbjct: 1118 LH 1119
>gi|17975768 ephrin receptor EphB3 precursor [Homo sapiens]
Length = 998
Score = 50.8 bits (120), Expect = 3e-06
Identities = 22/59 (37%), Positives = 42/59 (71%), Gaps = 1/59 (1%)
Query: 113 TSVAEWLDSIELGDYTKAFLINGYTSMDLLKKIWEVELINVLKINLIGHRKRILASLGD 171
T+V +WLD+I++G Y ++F+ G+ S DL+ ++ +L+ + + L GH+K+IL+S+ D
Sbjct: 928 TTVGDWLDAIKMGRYKESFVSAGFASFDLVAQMTAEDLLRI-GVTLAGHQKKILSSIQD 985
Score = 45.1 bits (105), Expect = 2e-04
Identities = 21/58 (36%), Positives = 37/58 (63%), Gaps = 2/58 (3%)
Query: 40 TVGQWLESIGLPQYENHLMANGFDNVQFMGSNVMEDQDLLEIGILNSGHRQRILQAIQ 97
TVG WL++I + +Y+ ++ GF + + M +DLL IG+ +GH+++IL +IQ
Sbjct: 929 TVGDWLDAIKMGRYKESFVSAGFASFDLVAQ--MTAEDLLRIGVTLAGHQKKILSSIQ 984
>gi|222446609 rai-like protein [Homo sapiens]
Length = 630
Score = 49.3 bits (116), Expect = 8e-06
Identities = 29/88 (32%), Positives = 51/88 (57%), Gaps = 3/88 (3%)
Query: 355 IILSVSYKGVKFIDATNKNIIAEHEIRNISCAA-QDPEDLSTFAYITKDLKSNHHYCHVF 413
I L++S + ++ N+ IIA H +++IS A+ DP+ AY+ KD N CH+
Sbjct: 262 IKLTISTCSLTLMNLDNQQIIANHHMQSISFASGGDPDTTDYVAYVAKD-PVNQRACHIL 320
Query: 414 TAFDVNLAYEIILTLGQAFEVAYQLALQ 441
+ +A ++I T+GQAFE+ ++ L+
Sbjct: 321 ECHN-GMAQDVISTIGQAFELRFKQYLK 347
>gi|148491082 disabled homolog 2 [Homo sapiens]
Length = 770
Score = 48.9 bits (115), Expect = 1e-05
Identities = 33/127 (25%), Positives = 57/127 (44%), Gaps = 4/127 (3%)
Query: 312 YKAFYLGSMLIKELRGTESTQDACAKMRANCQKSTEQMKKVPTIILSVSYKGVKFIDATN 371
YKA +G + + RG + +QD+ K++ Q + I +++S G+K ID
Sbjct: 50 YKAKLIGIDDVPDARGDKMSQDSMMKLKGMAAAGRSQGQHKQRIWVNISLSGIKIIDEKT 109
Query: 372 KNIIAEHEIRNISCAAQDPEDLSTFAYITKDLKSNHHYCHVFTAFDVNLAYEIILTLGQA 431
I EH + IS A+D D F Y+ + H + + T A +++ L
Sbjct: 110 GVIEHEHPVNKISFIARDVTDNRAFGYVCGG-EGQHQFFAIKTG---QQAEPLVVDLKDL 165
Query: 432 FEVAYQL 438
F+V Y +
Sbjct: 166 FQVIYNV 172
>gi|32528301 EPH receptor B4 precursor [Homo sapiens]
Length = 987
Score = 48.1 bits (113), Expect = 2e-05
Identities = 27/85 (31%), Positives = 45/85 (52%), Gaps = 6/85 (7%)
Query: 29 HPLTGPRCP----VQTVGQWLESIGLPQYENHLMANGFDNVQFMGSNVMEDQDLLEIGIL 84
HPL R P +VG+WL +I + +YE A GF + + + + +DLL IG+
Sbjct: 896 HPLLDQRQPHYSAFGSVGEWLRAIKMGRYEESFAAAGFGSFELVSQ--ISAEDLLRIGVT 953
Query: 85 NSGHRQRILQAIQLLPKMRPIGHDG 109
+GH+++IL ++Q + G G
Sbjct: 954 LAGHQKKILASVQHMKSQAKPGTPG 978
Score = 46.2 bits (108), Expect = 7e-05
Identities = 24/68 (35%), Positives = 40/68 (58%), Gaps = 1/68 (1%)
Query: 114 SVAEWLDSIELGDYTKAFLINGYTSMDLLKKIWEVELINVLKINLIGHRKRILASLGDRL 173
SV EWL +I++G Y ++F G+ S +L+ +I +L+ + + L GH+K+ILAS+
Sbjct: 911 SVGEWLRAIKMGRYEESFAAAGFGSFELVSQISAEDLLRI-GVTLAGHQKKILASVQHMK 969
Query: 174 HDDPPQKP 181
P P
Sbjct: 970 SQAKPGTP 977
>gi|10140845 ephrin receptor EphA8 isoform 1 precursor [Homo
sapiens]
Length = 1005
Score = 47.0 bits (110), Expect = 4e-05
Identities = 23/64 (35%), Positives = 38/64 (59%), Gaps = 1/64 (1%)
Query: 106 GHDGYHPTSVAEWLDSIELGDYTKAFLINGYTSMDLLKKIWEVELINVLKINLIGHRKRI 165
G G +V +WLDSI +G Y F GY+S+ ++ ++ + + L I L+GH+K+I
Sbjct: 926 GSGGGGGLTVGDWLDSIRMGRYRDHFAAGGYSSLGMVLRM-NAQDVRALGITLMGHQKKI 984
Query: 166 LASL 169
L S+
Sbjct: 985 LGSI 988
Score = 44.7 bits (104), Expect = 2e-04
Identities = 22/60 (36%), Positives = 37/60 (61%), Gaps = 2/60 (3%)
Query: 40 TVGQWLESIGLPQYENHLMANGFDNVQFMGSNVMEDQDLLEIGILNSGHRQRILQAIQLL 99
TVG WL+SI + +Y +H A G+ ++ + M QD+ +GI GH+++IL +IQ +
Sbjct: 934 TVGDWLDSIRMGRYRDHFAAGGYSSLGMVLR--MNAQDVRALGITLMGHQKKILGSIQTM 991
>gi|71834346 sterile alpha motif domain containing 5 [Homo
sapiens]
Length = 173
Score = 47.0 bits (110), Expect = 4e-05
Identities = 23/59 (38%), Positives = 38/59 (64%), Gaps = 2/59 (3%)
Query: 41 VGQWLESIGLPQYENHLMANGFDNVQFMGSNVMEDQDLLEIGILNSGHRQRILQAIQLL 99
V +WL+++ LPQY + NG+D+++ + D DL IG+L HR+RIL+A++ L
Sbjct: 6 VYEWLKALQLPQYAESFVDNGYDDLEV--CKQIGDPDLDAIGVLAPAHRRRILEAVRRL 62
Score = 40.0 bits (92), Expect = 0.005
Identities = 24/83 (28%), Positives = 43/83 (51%), Gaps = 2/83 (2%)
Query: 115 VAEWLDSIELGDYTKAFLINGYTSMDLLKKIWEVELINVLKINLIGHRKRILASLGDRLH 174
V EWL +++L Y ++F+ NGY +++ K+I + +L + + + HR+RIL ++ RL
Sbjct: 6 VYEWLKALQLPQYAESFVDNGYDDLEVCKQIGDPDL-DAIGVLAPAHRRRILEAV-RRLR 63
Query: 175 DDPPQKPPRSITLREPSGNHTPP 197
+ TL PP
Sbjct: 64 EQDANAAGLYFTLEPQPAPPGPP 86
Database: hs.faa
Posted date: Aug 4, 2009 4:42 PM
Number of letters in database: 18,247,518
Number of sequences in database: 37,866
Lambda K H
0.318 0.134 0.410
Gapped
Lambda K H
0.267 0.0410 0.140
Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Hits to DB: 21,018,743
Number of Sequences: 37866
Number of extensions: 988328
Number of successful extensions: 3313
Number of sequences better than 10.0: 30
Number of HSP's better than 10.0 without gapping: 48
Number of HSP's successfully gapped in prelim test: 33
Number of HSP's that attempted gapping in prelim test: 3136
Number of HSP's gapped (non-prelim): 144
length of query: 510
length of database: 18,247,518
effective HSP length: 107
effective length of query: 403
effective length of database: 14,195,856
effective search space: 5720929968
effective search space used: 5720929968
T: 11
A: 40
X1: 16 ( 7.3 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 41 (21.7 bits)
S2: 64 (29.3 bits)
Search results were obtained with NCBI BLAST and RefSeq entries.
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Guide to the Human Genome
Copyright © 2010 by Stewart Scherer. All rights reserved.