Guide to the Human Genome
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Search of human proteins with 5031821

BLASTP 2.2.11 [Jun-05-2005]


Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer, 
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), 
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs",  Nucleic Acids Res. 25:3389-3402.

Query= gi|5031821 potassium channel, subfamily K, member 7 isoform C
[Homo sapiens]
         (257 letters)

Database: hs.faa 
           37,866 sequences; 18,247,518 total letters

Searching..................................................done

                                                                 Score    E
Sequences producing significant alignments:                      (bits) Value

gi|5031821 potassium channel, subfamily K, member 7 isoform C [H...   513   e-146
gi|16118235 potassium channel, subfamily K, member 7 isoform B [...   479   e-136
gi|16118233 potassium channel, subfamily K, member 7 isoform B [...   479   e-136
gi|16118231 potassium channel, subfamily K, member 7 isoform A [...   478   e-135
gi|4504847 potassium channel, subfamily K, member 1 [Homo sapiens]    172   3e-43
gi|4758624 potassium channel, subfamily K, member 6 [Homo sapiens]    132   3e-31
gi|14589851 potassium channel, subfamily K, member 2 isoform b [...   110   9e-25
gi|126365795 potassium channel, subfamily K, member 2 isoform c ...   110   9e-25
gi|62912487 potassium channel, subfamily K, member 2 isoform a [...   110   9e-25
gi|20143946 potassium channel, subfamily K, member 10 isoform 3 ...   110   9e-25
gi|20143944 potassium channel, subfamily K, member 10 isoform 2 ...   110   9e-25
gi|10863961 potassium channel, subfamily K, member 10 isoform 1 ...   110   9e-25
gi|205360983 potassium channel, subfamily K, member 16 isoform 3...   107   1e-23
gi|14149764 potassium channel, subfamily K, member 16 isoform 2 ...   107   1e-23
gi|205360973 potassium channel, subfamily K, member 16 isoform 4...   105   5e-23
gi|205360971 potassium channel, subfamily K, member 16 isoform 1...   105   5e-23
gi|17025230 potassium channel, subfamily K, member 17 isoform 1 ...    94   9e-20
gi|205361107 potassium channel, subfamily K, member 17 isoform 2...    92   6e-19
gi|15718767 TRAAK [Homo sapiens]                                       91   1e-18
gi|11641275 potassium family, subfamily K, member 15 [Homo sapiens]    87   1e-17
gi|4504849 potassium channel, subfamily K, member 3 [Homo sapiens]     84   2e-16
gi|4504851 potassium channel, subfamily K, member 5 [Homo sapiens]     81   1e-15
gi|7706135 potassium channel, subfamily K, member 9 [Homo sapiens]     75   6e-14
gi|11545761 potassium channel, subfamily K, member 12 [Homo sapi...    69   3e-12
gi|16306555 potassium channel, subfamily K, member 13 [Homo sapi...    54   1e-07
gi|32469495 potassium channel, subfamily K, member 18 [Homo sapi...    47   1e-05
gi|170650615 protoporphyrinogen oxidase [Homo sapiens]                 36   0.029
gi|4506001 protoporphyrinogen oxidase [Homo sapiens]                   36   0.029
gi|5031819 potassium voltage-gated channel, shaker-related subfa...    34   0.11 
gi|25952092 potassium voltage-gated channel, shaker-related subf...    33   0.19 

>gi|5031821 potassium channel, subfamily K, member 7 isoform C [Homo
           sapiens]
          Length = 257

 Score =  513 bits (1320), Expect = e-146
 Identities = 257/257 (100%), Positives = 257/257 (100%)

Query: 1   MGGLRPWSRYGLLVVAHLLALGLGAVVFQALEGPPACRLQAELRAELAAFQAEHRACLPP 60
           MGGLRPWSRYGLLVVAHLLALGLGAVVFQALEGPPACRLQAELRAELAAFQAEHRACLPP
Sbjct: 1   MGGLRPWSRYGLLVVAHLLALGLGAVVFQALEGPPACRLQAELRAELAAFQAEHRACLPP 60

Query: 61  GALEELLGTALATQAHGVSTLGNSSEGRTWDLPSALLFAASILTTTGYGHMAPLSPGGKA 120
           GALEELLGTALATQAHGVSTLGNSSEGRTWDLPSALLFAASILTTTGYGHMAPLSPGGKA
Sbjct: 61  GALEELLGTALATQAHGVSTLGNSSEGRTWDLPSALLFAASILTTTGYGHMAPLSPGGKA 120

Query: 121 FCMVYAALGLPASLALVATLRHCLLPVLSRPRAWVAVHWQLSPARAALLQAVALGLLVAS 180
           FCMVYAALGLPASLALVATLRHCLLPVLSRPRAWVAVHWQLSPARAALLQAVALGLLVAS
Sbjct: 121 FCMVYAALGLPASLALVATLRHCLLPVLSRPRAWVAVHWQLSPARAALLQAVALGLLVAS 180

Query: 181 SFVLLPALVLWGLQGDCSLLGAVYFCFSSLSTIGLEDLLPGRGRSLHPVIYHLGQLALLG 240
           SFVLLPALVLWGLQGDCSLLGAVYFCFSSLSTIGLEDLLPGRGRSLHPVIYHLGQLALLG
Sbjct: 181 SFVLLPALVLWGLQGDCSLLGAVYFCFSSLSTIGLEDLLPGRGRSLHPVIYHLGQLALLG 240

Query: 241 KSSHLTACGGRGKRSLD 257
           KSSHLTACGGRGKRSLD
Sbjct: 241 KSSHLTACGGRGKRSLD 257


>gi|16118235 potassium channel, subfamily K, member 7 isoform B
           [Homo sapiens]
          Length = 252

 Score =  479 bits (1234), Expect = e-136
 Identities = 242/252 (96%), Positives = 243/252 (96%)

Query: 1   MGGLRPWSRYGLLVVAHLLALGLGAVVFQALEGPPACRLQAELRAELAAFQAEHRACLPP 60
           MGGLRPWSRYGLLVVAHLLALGLGAVVFQALEGPPACRLQAELRAELAAFQAEHRACLPP
Sbjct: 1   MGGLRPWSRYGLLVVAHLLALGLGAVVFQALEGPPACRLQAELRAELAAFQAEHRACLPP 60

Query: 61  GALEELLGTALATQAHGVSTLGNSSEGRTWDLPSALLFAASILTTTGYGHMAPLSPGGKA 120
           GALEELLGTALATQAHGVSTLGNSSEGRTWDLPSALLFAASILTTTGYGHMAPLSPGGKA
Sbjct: 61  GALEELLGTALATQAHGVSTLGNSSEGRTWDLPSALLFAASILTTTGYGHMAPLSPGGKA 120

Query: 121 FCMVYAALGLPASLALVATLRHCLLPVLSRPRAWVAVHWQLSPARAALLQAVALGLLVAS 180
           FCMVYAALGLPASLALVATLRHCLLPVLSRPRAWVAVHWQLSPARAALLQAVALGLLVAS
Sbjct: 121 FCMVYAALGLPASLALVATLRHCLLPVLSRPRAWVAVHWQLSPARAALLQAVALGLLVAS 180

Query: 181 SFVLLPALVLWGLQGDCSLLGAVYFCFSSLSTIGLEDLLPGRGRSLHPVIYHLGQLALLG 240
           SFVLLPALVLWGLQGDCSLLGAVYFCFSSLSTIGLEDLLPGRGRSLHPVIYHLGQLALLG
Sbjct: 181 SFVLLPALVLWGLQGDCSLLGAVYFCFSSLSTIGLEDLLPGRGRSLHPVIYHLGQLALLG 240

Query: 241 KSSHLTACGGRG 252
             + L      G
Sbjct: 241 GGTSLQGTAWEG 252


>gi|16118233 potassium channel, subfamily K, member 7 isoform B
           [Homo sapiens]
          Length = 252

 Score =  479 bits (1234), Expect = e-136
 Identities = 242/252 (96%), Positives = 243/252 (96%)

Query: 1   MGGLRPWSRYGLLVVAHLLALGLGAVVFQALEGPPACRLQAELRAELAAFQAEHRACLPP 60
           MGGLRPWSRYGLLVVAHLLALGLGAVVFQALEGPPACRLQAELRAELAAFQAEHRACLPP
Sbjct: 1   MGGLRPWSRYGLLVVAHLLALGLGAVVFQALEGPPACRLQAELRAELAAFQAEHRACLPP 60

Query: 61  GALEELLGTALATQAHGVSTLGNSSEGRTWDLPSALLFAASILTTTGYGHMAPLSPGGKA 120
           GALEELLGTALATQAHGVSTLGNSSEGRTWDLPSALLFAASILTTTGYGHMAPLSPGGKA
Sbjct: 61  GALEELLGTALATQAHGVSTLGNSSEGRTWDLPSALLFAASILTTTGYGHMAPLSPGGKA 120

Query: 121 FCMVYAALGLPASLALVATLRHCLLPVLSRPRAWVAVHWQLSPARAALLQAVALGLLVAS 180
           FCMVYAALGLPASLALVATLRHCLLPVLSRPRAWVAVHWQLSPARAALLQAVALGLLVAS
Sbjct: 121 FCMVYAALGLPASLALVATLRHCLLPVLSRPRAWVAVHWQLSPARAALLQAVALGLLVAS 180

Query: 181 SFVLLPALVLWGLQGDCSLLGAVYFCFSSLSTIGLEDLLPGRGRSLHPVIYHLGQLALLG 240
           SFVLLPALVLWGLQGDCSLLGAVYFCFSSLSTIGLEDLLPGRGRSLHPVIYHLGQLALLG
Sbjct: 181 SFVLLPALVLWGLQGDCSLLGAVYFCFSSLSTIGLEDLLPGRGRSLHPVIYHLGQLALLG 240

Query: 241 KSSHLTACGGRG 252
             + L      G
Sbjct: 241 GGTSLQGTAWEG 252


>gi|16118231 potassium channel, subfamily K, member 7 isoform A
           [Homo sapiens]
          Length = 307

 Score =  478 bits (1230), Expect = e-135
 Identities = 240/240 (100%), Positives = 240/240 (100%)

Query: 1   MGGLRPWSRYGLLVVAHLLALGLGAVVFQALEGPPACRLQAELRAELAAFQAEHRACLPP 60
           MGGLRPWSRYGLLVVAHLLALGLGAVVFQALEGPPACRLQAELRAELAAFQAEHRACLPP
Sbjct: 1   MGGLRPWSRYGLLVVAHLLALGLGAVVFQALEGPPACRLQAELRAELAAFQAEHRACLPP 60

Query: 61  GALEELLGTALATQAHGVSTLGNSSEGRTWDLPSALLFAASILTTTGYGHMAPLSPGGKA 120
           GALEELLGTALATQAHGVSTLGNSSEGRTWDLPSALLFAASILTTTGYGHMAPLSPGGKA
Sbjct: 61  GALEELLGTALATQAHGVSTLGNSSEGRTWDLPSALLFAASILTTTGYGHMAPLSPGGKA 120

Query: 121 FCMVYAALGLPASLALVATLRHCLLPVLSRPRAWVAVHWQLSPARAALLQAVALGLLVAS 180
           FCMVYAALGLPASLALVATLRHCLLPVLSRPRAWVAVHWQLSPARAALLQAVALGLLVAS
Sbjct: 121 FCMVYAALGLPASLALVATLRHCLLPVLSRPRAWVAVHWQLSPARAALLQAVALGLLVAS 180

Query: 181 SFVLLPALVLWGLQGDCSLLGAVYFCFSSLSTIGLEDLLPGRGRSLHPVIYHLGQLALLG 240
           SFVLLPALVLWGLQGDCSLLGAVYFCFSSLSTIGLEDLLPGRGRSLHPVIYHLGQLALLG
Sbjct: 181 SFVLLPALVLWGLQGDCSLLGAVYFCFSSLSTIGLEDLLPGRGRSLHPVIYHLGQLALLG 240


>gi|4504847 potassium channel, subfamily K, member 1 [Homo sapiens]
          Length = 336

 Score =  172 bits (436), Expect = 3e-43
 Identities = 95/215 (44%), Positives = 127/215 (59%), Gaps = 2/215 (0%)

Query: 10  YGLLVVAHLLALGLGAVVFQALEGPPACRLQAELRAELAAFQAEHRACLPPGALEELLGT 69
           +G LV+ +LL L  GAVVF ++E P    L+ ELR     F  EH  CL    LE+ LG 
Sbjct: 23  FGFLVLGYLLYLVFGAVVFSSVELPYEDLLRQELRKLKRRFLEEHE-CLSEQQLEQFLGR 81

Query: 70  ALATQAHGVSTLGNSSEGRTWDLPSALLFAASILTTTGYGHMAPLSPGGKAFCMVYAALG 129
            L    +GVS L N+S    WD  SAL FA+++L+TTGYGH  PLS GGKAFC++Y+ +G
Sbjct: 82  VLEASNYGVSVLSNASGNWNWDFTSALFFASTVLSTTGYGHTVPLSDGGKAFCIIYSVIG 141

Query: 130 LPASLA-LVATLRHCLLPVLSRPRAWVAVHWQLSPARAALLQAVALGLLVASSFVLLPAL 188
           +P +L  L A ++   + V  RP  +  + W  S    A++ AV LG +  S F  +PA 
Sbjct: 142 IPFTLLFLTAVVQRITVHVTRRPVLYFHIRWGFSKQVVAIVHAVLLGFVTVSCFFFIPAA 201

Query: 189 VLWGLQGDCSLLGAVYFCFSSLSTIGLEDLLPGRG 223
           V   L+ D + L + YFCF SLSTIGL D +PG G
Sbjct: 202 VFSVLEDDWNFLESFYFCFISLSTIGLGDYVPGEG 236


>gi|4758624 potassium channel, subfamily K, member 6 [Homo sapiens]
          Length = 313

 Score =  132 bits (332), Expect = 3e-31
 Identities = 86/228 (37%), Positives = 123/228 (53%), Gaps = 12/228 (5%)

Query: 14  VVAHLLALGLGAVVFQALEGPPACRLQAELRAELAAFQAEHRACLPPGALEELLGTALAT 73
           + A+   L LGA++   LEGP   RL+AEL   L A   +   C+   AL+  +   LA 
Sbjct: 11  LAAYAAYLVLGALLVARLEGPHEARLRAELET-LRAQLLQRSPCVAAPALDAFVERVLAA 69

Query: 74  QAHGVSTLGNSSEGRT-----WDLPSALLFAASILTTTGYGHMAPLSPGGKAFCMVYAAL 128
              G   L N+S         WD  SAL FA++++TT GYG+  PL+  GKAF + +A L
Sbjct: 70  GRLGRVVLANASGSANASDPAWDFASALFFASTLITTVGYGYTTPLTDAGKAFSIAFALL 129

Query: 129 GLPAS-LALVATLRHCLLPVLSRPRAWVAVHWQLSPARAALLQAVALGLLVASSFVLLPA 187
           G+P + L L A+ +   L +   P +W+++ W   P RAA    VAL  +V +   L+PA
Sbjct: 130 GVPTTMLLLTASAQRLSLLLTHVPLSWLSMRWGWDPRRAACWHLVALLGVVVTVCFLVPA 189

Query: 188 LVLWGLQGDCSLLGAVYFCFSSLSTIGLEDLLPGRG-----RSLHPVI 230
           ++   L+   S L A YFCF SLSTIGL D +PG       R+L+ V+
Sbjct: 190 VIFAHLEEAWSFLDAFYFCFISLSTIGLGDYVPGEAPGQPYRALYKVL 237



 Score = 28.5 bits (62), Expect = 6.0
 Identities = 19/60 (31%), Positives = 23/60 (38%), Gaps = 7/60 (11%)

Query: 90  WDLPSALLFAASILTTTGYGHMAPLSPGG-------KAFCMVYAALGLPASLALVATLRH 142
           W    A  F    L+T G G   P    G       K    VY  LGL A + ++ T RH
Sbjct: 199 WSFLDAFYFCFISLSTIGLGDYVPGEAPGQPYRALYKVLVTVYLFLGLVAMVLVLQTFRH 258


>gi|14589851 potassium channel, subfamily K, member 2 isoform b
           [Homo sapiens]
          Length = 411

 Score =  110 bits (276), Expect = 9e-25
 Identities = 69/219 (31%), Positives = 117/219 (53%), Gaps = 6/219 (2%)

Query: 7   WSRYGLLVVAHLLALGLGAVVFQALEGPPACRLQAELRAELAAFQAEHRACLPPGALEEL 66
           W     + +  +L L +GA VF+ALE P     +  +  +   F ++H +C+    L+EL
Sbjct: 44  WKTVSTIFLVVVLYLIIGATVFKALEQPHEISQRTTIVIQKQTFISQH-SCVNSTELDEL 102

Query: 67  LGTALATQAHGVSTLGNSSEGRT-WDLPSALLFAASILTTTGYGHMAPLSPGGKAFCMVY 125
           +   +A    G+  LGN+S   + WDL S+  FA +++TT G+G+++P + GGK FC++Y
Sbjct: 103 IQQIVAAINAGIIPLGNTSNQISHWDLGSSFFFAGTVITTIGFGNISPRTEGGKIFCIIY 162

Query: 126 AALGLPASLALVATLRHCLLPVLSRPRAWVA---VHWQLSPARAALLQAVALGLLVASSF 182
           A LG+P    L+A +   L  +  +  A V    + W +S  +  ++  +   L     F
Sbjct: 163 ALLGIPLFGFLLAGVGDQLGTIFGKGIAKVEDTFIKWNVSQTKIRIISTIIFILFGCVLF 222

Query: 183 VLLPALVLWGLQGDCSLLGAVYFCFSSLSTIGLEDLLPG 221
           V LPA++   ++G  S L A+YF   +L+TIG  D + G
Sbjct: 223 VALPAIIFKHIEG-WSALDAIYFVVITLTTIGFGDYVAG 260


>gi|126365795 potassium channel, subfamily K, member 2 isoform c
           [Homo sapiens]
          Length = 426

 Score =  110 bits (276), Expect = 9e-25
 Identities = 69/219 (31%), Positives = 117/219 (53%), Gaps = 6/219 (2%)

Query: 7   WSRYGLLVVAHLLALGLGAVVFQALEGPPACRLQAELRAELAAFQAEHRACLPPGALEEL 66
           W     + +  +L L +GA VF+ALE P     +  +  +   F ++H +C+    L+EL
Sbjct: 59  WKTVSTIFLVVVLYLIIGATVFKALEQPHEISQRTTIVIQKQTFISQH-SCVNSTELDEL 117

Query: 67  LGTALATQAHGVSTLGNSSEGRT-WDLPSALLFAASILTTTGYGHMAPLSPGGKAFCMVY 125
           +   +A    G+  LGN+S   + WDL S+  FA +++TT G+G+++P + GGK FC++Y
Sbjct: 118 IQQIVAAINAGIIPLGNTSNQISHWDLGSSFFFAGTVITTIGFGNISPRTEGGKIFCIIY 177

Query: 126 AALGLPASLALVATLRHCLLPVLSRPRAWVA---VHWQLSPARAALLQAVALGLLVASSF 182
           A LG+P    L+A +   L  +  +  A V    + W +S  +  ++  +   L     F
Sbjct: 178 ALLGIPLFGFLLAGVGDQLGTIFGKGIAKVEDTFIKWNVSQTKIRIISTIIFILFGCVLF 237

Query: 183 VLLPALVLWGLQGDCSLLGAVYFCFSSLSTIGLEDLLPG 221
           V LPA++   ++G  S L A+YF   +L+TIG  D + G
Sbjct: 238 VALPAIIFKHIEG-WSALDAIYFVVITLTTIGFGDYVAG 275


>gi|62912487 potassium channel, subfamily K, member 2 isoform a
           [Homo sapiens]
          Length = 422

 Score =  110 bits (276), Expect = 9e-25
 Identities = 69/219 (31%), Positives = 117/219 (53%), Gaps = 6/219 (2%)

Query: 7   WSRYGLLVVAHLLALGLGAVVFQALEGPPACRLQAELRAELAAFQAEHRACLPPGALEEL 66
           W     + +  +L L +GA VF+ALE P     +  +  +   F ++H +C+    L+EL
Sbjct: 55  WKTVSTIFLVVVLYLIIGATVFKALEQPHEISQRTTIVIQKQTFISQH-SCVNSTELDEL 113

Query: 67  LGTALATQAHGVSTLGNSSEGRT-WDLPSALLFAASILTTTGYGHMAPLSPGGKAFCMVY 125
           +   +A    G+  LGN+S   + WDL S+  FA +++TT G+G+++P + GGK FC++Y
Sbjct: 114 IQQIVAAINAGIIPLGNTSNQISHWDLGSSFFFAGTVITTIGFGNISPRTEGGKIFCIIY 173

Query: 126 AALGLPASLALVATLRHCLLPVLSRPRAWVA---VHWQLSPARAALLQAVALGLLVASSF 182
           A LG+P    L+A +   L  +  +  A V    + W +S  +  ++  +   L     F
Sbjct: 174 ALLGIPLFGFLLAGVGDQLGTIFGKGIAKVEDTFIKWNVSQTKIRIISTIIFILFGCVLF 233

Query: 183 VLLPALVLWGLQGDCSLLGAVYFCFSSLSTIGLEDLLPG 221
           V LPA++   ++G  S L A+YF   +L+TIG  D + G
Sbjct: 234 VALPAIIFKHIEG-WSALDAIYFVVITLTTIGFGDYVAG 271


>gi|20143946 potassium channel, subfamily K, member 10 isoform 3
           [Homo sapiens]
          Length = 543

 Score =  110 bits (276), Expect = 9e-25
 Identities = 75/227 (33%), Positives = 119/227 (52%), Gaps = 9/227 (3%)

Query: 2   GGLRP---WSRYGLLVVAHLLALGLGAVVFQALEGPPACRLQAELRAELAAFQAEHRACL 58
           GGL+    W     + V  ++ L  G +VF+ALE P     +  +  E A F  +H  C+
Sbjct: 66  GGLQTVMKWKTVVAIFVVVVVYLVTGGLVFRALEQPFESSQKNTIALEKAEFLRDH-VCV 124

Query: 59  PPGALEELLGTALATQAHGVSTLGNSSEGRT-WDLPSALLFAASILTTTGYGHMAPLSPG 117
            P  LE L+  AL     GVS +GNSS   + WDL SA  FA +++TT GYG++AP + G
Sbjct: 125 SPQELETLIQHALDADNAGVSPIGNSSNNSSHWDLGSAFFFAGTVITTIGYGNIAPSTEG 184

Query: 118 GKAFCMVYAALGLPASLALVATLRHCLLPVLSRPRAWVAVHW---QLSPARAALLQAVAL 174
           GK FC++YA  G+P    L+A +   L  +  +  A V   +   Q+S  +  ++  +  
Sbjct: 185 GKIFCILYAIFGIPLFGFLLAGIGDQLGTIFGKSIARVEKVFRKKQVSQTKIRVISTILF 244

Query: 175 GLLVASSFVLLPALVLWGLQGDCSLLGAVYFCFSSLSTIGLEDLLPG 221
            L     FV +PA++   ++G  + L ++YF   +L+T+G  D + G
Sbjct: 245 ILAGCIVFVTIPAVIFKYIEG-WTALESIYFVVVTLTTVGFGDFVAG 290


>gi|20143944 potassium channel, subfamily K, member 10 isoform 2
           [Homo sapiens]
          Length = 543

 Score =  110 bits (276), Expect = 9e-25
 Identities = 75/227 (33%), Positives = 119/227 (52%), Gaps = 9/227 (3%)

Query: 2   GGLRP---WSRYGLLVVAHLLALGLGAVVFQALEGPPACRLQAELRAELAAFQAEHRACL 58
           GGL+    W     + V  ++ L  G +VF+ALE P     +  +  E A F  +H  C+
Sbjct: 66  GGLQTVMKWKTVVAIFVVVVVYLVTGGLVFRALEQPFESSQKNTIALEKAEFLRDH-VCV 124

Query: 59  PPGALEELLGTALATQAHGVSTLGNSSEGRT-WDLPSALLFAASILTTTGYGHMAPLSPG 117
            P  LE L+  AL     GVS +GNSS   + WDL SA  FA +++TT GYG++AP + G
Sbjct: 125 SPQELETLIQHALDADNAGVSPIGNSSNNSSHWDLGSAFFFAGTVITTIGYGNIAPSTEG 184

Query: 118 GKAFCMVYAALGLPASLALVATLRHCLLPVLSRPRAWVAVHW---QLSPARAALLQAVAL 174
           GK FC++YA  G+P    L+A +   L  +  +  A V   +   Q+S  +  ++  +  
Sbjct: 185 GKIFCILYAIFGIPLFGFLLAGIGDQLGTIFGKSIARVEKVFRKKQVSQTKIRVISTILF 244

Query: 175 GLLVASSFVLLPALVLWGLQGDCSLLGAVYFCFSSLSTIGLEDLLPG 221
            L     FV +PA++   ++G  + L ++YF   +L+T+G  D + G
Sbjct: 245 ILAGCIVFVTIPAVIFKYIEG-WTALESIYFVVVTLTTVGFGDFVAG 290


>gi|10863961 potassium channel, subfamily K, member 10 isoform 1
           [Homo sapiens]
          Length = 538

 Score =  110 bits (276), Expect = 9e-25
 Identities = 75/227 (33%), Positives = 119/227 (52%), Gaps = 9/227 (3%)

Query: 2   GGLRP---WSRYGLLVVAHLLALGLGAVVFQALEGPPACRLQAELRAELAAFQAEHRACL 58
           GGL+    W     + V  ++ L  G +VF+ALE P     +  +  E A F  +H  C+
Sbjct: 61  GGLQTVMKWKTVVAIFVVVVVYLVTGGLVFRALEQPFESSQKNTIALEKAEFLRDH-VCV 119

Query: 59  PPGALEELLGTALATQAHGVSTLGNSSEGRT-WDLPSALLFAASILTTTGYGHMAPLSPG 117
            P  LE L+  AL     GVS +GNSS   + WDL SA  FA +++TT GYG++AP + G
Sbjct: 120 SPQELETLIQHALDADNAGVSPIGNSSNNSSHWDLGSAFFFAGTVITTIGYGNIAPSTEG 179

Query: 118 GKAFCMVYAALGLPASLALVATLRHCLLPVLSRPRAWVAVHW---QLSPARAALLQAVAL 174
           GK FC++YA  G+P    L+A +   L  +  +  A V   +   Q+S  +  ++  +  
Sbjct: 180 GKIFCILYAIFGIPLFGFLLAGIGDQLGTIFGKSIARVEKVFRKKQVSQTKIRVISTILF 239

Query: 175 GLLVASSFVLLPALVLWGLQGDCSLLGAVYFCFSSLSTIGLEDLLPG 221
            L     FV +PA++   ++G  + L ++YF   +L+T+G  D + G
Sbjct: 240 ILAGCIVFVTIPAVIFKYIEG-WTALESIYFVVVTLTTVGFGDFVAG 285


>gi|205360983 potassium channel, subfamily K, member 16 isoform 3
           [Homo sapiens]
          Length = 294

 Score =  107 bits (267), Expect = 1e-23
 Identities = 73/218 (33%), Positives = 111/218 (50%), Gaps = 10/218 (4%)

Query: 13  LVVAHLLALGLGAVVFQALEGPPACRLQAELRAELAAFQAEHRACLPPGALEELLGTALA 72
           L++A++  L LGA +FQ LE     + + + + E   F  E+  CL   A+E+ +   + 
Sbjct: 17  LLLAYVCYLLLGATIFQLLERQAEAQSRDQFQLEKLRF-LENYTCLDQWAMEQFVQVIME 75

Query: 73  TQAHGVSTLGNSSEGRTWDLPSALLFAASILTTTGYGHMAPLSPGGKAFCMVYAALGLPA 132
               GV+  GNS+    WD  S+  FA +++TT GYG++AP +  G+ FC+ YA LG+P 
Sbjct: 76  AWVKGVNPKGNSTNPSNWDFGSSFFFAGTVVTTIGYGNLAPSTEAGQVFCVFYALLGIPL 135

Query: 133 SLALVATLRHCLLPVLSRPRAWVAVHWQLSPARAALLQAVALGL-LVASSFVLL--PALV 189
           +   V  L H  L    R        W+  P R+ +LQ + L L L   + V+L  P +V
Sbjct: 136 N---VIFLNH--LGTGLRAHLAAIERWEDRPRRSQVLQVLGLALFLTLGTLVILIFPPMV 190

Query: 190 LWGLQGDCSLLGAVYFCFSSLSTIGLEDLLPGRGRSLH 227
              ++G  S     YF F +LSTIG  D + G   S H
Sbjct: 191 FSHVEG-WSFSEGFYFAFITLSTIGFGDYVVGTDPSKH 227


>gi|14149764 potassium channel, subfamily K, member 16 isoform 2
           [Homo sapiens]
          Length = 309

 Score =  107 bits (267), Expect = 1e-23
 Identities = 73/218 (33%), Positives = 111/218 (50%), Gaps = 10/218 (4%)

Query: 13  LVVAHLLALGLGAVVFQALEGPPACRLQAELRAELAAFQAEHRACLPPGALEELLGTALA 72
           L++A++  L LGA +FQ LE     + + + + E   F  E+  CL   A+E+ +   + 
Sbjct: 17  LLLAYVCYLLLGATIFQLLERQAEAQSRDQFQLEKLRF-LENYTCLDQWAMEQFVQVIME 75

Query: 73  TQAHGVSTLGNSSEGRTWDLPSALLFAASILTTTGYGHMAPLSPGGKAFCMVYAALGLPA 132
               GV+  GNS+    WD  S+  FA +++TT GYG++AP +  G+ FC+ YA LG+P 
Sbjct: 76  AWVKGVNPKGNSTNPSNWDFGSSFFFAGTVVTTIGYGNLAPSTEAGQVFCVFYALLGIPL 135

Query: 133 SLALVATLRHCLLPVLSRPRAWVAVHWQLSPARAALLQAVALGL-LVASSFVLL--PALV 189
           +   V  L H  L    R        W+  P R+ +LQ + L L L   + V+L  P +V
Sbjct: 136 N---VIFLNH--LGTGLRAHLAAIERWEDRPRRSQVLQVLGLALFLTLGTLVILIFPPMV 190

Query: 190 LWGLQGDCSLLGAVYFCFSSLSTIGLEDLLPGRGRSLH 227
              ++G  S     YF F +LSTIG  D + G   S H
Sbjct: 191 FSHVEG-WSFSEGFYFAFITLSTIGFGDYVVGTDPSKH 227


>gi|205360973 potassium channel, subfamily K, member 16 isoform 4
           [Homo sapiens]
          Length = 262

 Score =  105 bits (261), Expect = 5e-23
 Identities = 71/212 (33%), Positives = 109/212 (51%), Gaps = 10/212 (4%)

Query: 13  LVVAHLLALGLGAVVFQALEGPPACRLQAELRAELAAFQAEHRACLPPGALEELLGTALA 72
           L++A++  L LGA +FQ LE     + + + + E   F  E+  CL   A+E+ +   + 
Sbjct: 17  LLLAYVCYLLLGATIFQLLERQAEAQSRDQFQLEKLRF-LENYTCLDQWAMEQFVQVIME 75

Query: 73  TQAHGVSTLGNSSEGRTWDLPSALLFAASILTTTGYGHMAPLSPGGKAFCMVYAALGLPA 132
               GV+  GNS+    WD  S+  FA +++TT GYG++AP +  G+ FC+ YA LG+P 
Sbjct: 76  AWVKGVNPKGNSTNPSNWDFGSSFFFAGTVVTTIGYGNLAPSTEAGQVFCVFYALLGIPL 135

Query: 133 SLALVATLRHCLLPVLSRPRAWVAVHWQLSPARAALLQAVALGL-LVASSFVLL--PALV 189
           +   V  L H  L    R        W+  P R+ +LQ + L L L   + V+L  P +V
Sbjct: 136 N---VIFLNH--LGTGLRAHLAAIERWEDRPRRSQVLQVLGLALFLTLGTLVILIFPPMV 190

Query: 190 LWGLQGDCSLLGAVYFCFSSLSTIGLEDLLPG 221
              ++G  S     YF F +LSTIG  D + G
Sbjct: 191 FSHVEG-WSFSEGFYFAFITLSTIGFGDYVVG 221


>gi|205360971 potassium channel, subfamily K, member 16 isoform 1
           [Homo sapiens]
          Length = 322

 Score =  105 bits (261), Expect = 5e-23
 Identities = 71/212 (33%), Positives = 109/212 (51%), Gaps = 10/212 (4%)

Query: 13  LVVAHLLALGLGAVVFQALEGPPACRLQAELRAELAAFQAEHRACLPPGALEELLGTALA 72
           L++A++  L LGA +FQ LE     + + + + E   F  E+  CL   A+E+ +   + 
Sbjct: 17  LLLAYVCYLLLGATIFQLLERQAEAQSRDQFQLEKLRF-LENYTCLDQWAMEQFVQVIME 75

Query: 73  TQAHGVSTLGNSSEGRTWDLPSALLFAASILTTTGYGHMAPLSPGGKAFCMVYAALGLPA 132
               GV+  GNS+    WD  S+  FA +++TT GYG++AP +  G+ FC+ YA LG+P 
Sbjct: 76  AWVKGVNPKGNSTNPSNWDFGSSFFFAGTVVTTIGYGNLAPSTEAGQVFCVFYALLGIPL 135

Query: 133 SLALVATLRHCLLPVLSRPRAWVAVHWQLSPARAALLQAVALGL-LVASSFVLL--PALV 189
           +   V  L H  L    R        W+  P R+ +LQ + L L L   + V+L  P +V
Sbjct: 136 N---VIFLNH--LGTGLRAHLAAIERWEDRPRRSQVLQVLGLALFLTLGTLVILIFPPMV 190

Query: 190 LWGLQGDCSLLGAVYFCFSSLSTIGLEDLLPG 221
              ++G  S     YF F +LSTIG  D + G
Sbjct: 191 FSHVEG-WSFSEGFYFAFITLSTIGFGDYVVG 221


>gi|17025230 potassium channel, subfamily K, member 17 isoform 1
           [Homo sapiens]
          Length = 332

 Score = 94.4 bits (233), Expect = 9e-20
 Identities = 67/230 (29%), Positives = 116/230 (50%), Gaps = 9/230 (3%)

Query: 12  LLVVAHLLALGLGAVVFQALEGPPACRLQAELRAELAAFQAEHRACLPPGALEELLGTAL 71
           LL++A+L  L LG  VF  LEG  A       + +      ++  CL   AL+ L+   +
Sbjct: 24  LLLLAYLAYLALGTGVFWTLEGRAAQDSSRSFQRDKWEL-LQNFTCLDRPALDSLIRDVV 82

Query: 72  ATQAHGVSTLGNSSEGRTWDLPSALLFAASILTTTGYGHMAPLSPGGKAFCMVYAALGLP 131
               +G S L N++    W+L  +  F+ S +TT GYG+++P +   + FC+ +A +G+P
Sbjct: 83  QAYKNGASLLSNTTSMGRWELVGSFFFSVSTITTIGYGNLSPNTMAARLFCIFFALVGIP 142

Query: 132 ASLALVATLRHCLLPVLSRPRAWVAVHWQLSPARAALLQ---AVALGLLVASSFVLLPAL 188
            +L ++  L H +   ++   + +   WQ  P +A  L    A+  GLL+   F+LLP L
Sbjct: 143 LNLVVLNRLGHLMQQGVNHWASRLGGTWQ-DPDKARWLAGSGALLSGLLL---FLLLPPL 198

Query: 189 VLWGLQGDCSLLGAVYFCFSSLSTIGLEDLLPGRGRSLHPVIYHLGQLAL 238
           +   ++G  S     YF F +LST+G  D + G   S    +++   ++L
Sbjct: 199 LFSHMEG-WSYTEGFYFAFITLSTVGFGDYVIGMNPSQRYPLWYKNMVSL 247


>gi|205361107 potassium channel, subfamily K, member 17 isoform 2
           [Homo sapiens]
          Length = 271

 Score = 91.7 bits (226), Expect = 6e-19
 Identities = 64/209 (30%), Positives = 107/209 (51%), Gaps = 9/209 (4%)

Query: 12  LLVVAHLLALGLGAVVFQALEGPPACRLQAELRAELAAFQAEHRACLPPGALEELLGTAL 71
           LL++A+L  L LG  VF  LEG  A       + +      ++  CL   AL+ L+   +
Sbjct: 24  LLLLAYLAYLALGTGVFWTLEGRAAQDSSRSFQRDKWEL-LQNFTCLDRPALDSLIRDVV 82

Query: 72  ATQAHGVSTLGNSSEGRTWDLPSALLFAASILTTTGYGHMAPLSPGGKAFCMVYAALGLP 131
               +G S L N++    W+L  +  F+ S +TT GYG+++P +   + FC+ +A +G+P
Sbjct: 83  QAYKNGASLLSNTTSMGRWELVGSFFFSVSTITTIGYGNLSPNTMAARLFCIFFALVGIP 142

Query: 132 ASLALVATLRHCLLPVLSRPRAWVAVHWQLSPARAALLQ---AVALGLLVASSFVLLPAL 188
            +L ++  L H +   ++   + +   WQ  P +A  L    A+  GLL+   F+LLP L
Sbjct: 143 LNLVVLNRLGHLMQQGVNHWASRLGGTWQ-DPDKARWLAGSGALLSGLLL---FLLLPPL 198

Query: 189 VLWGLQGDCSLLGAVYFCFSSLSTIGLED 217
           +   ++G  S     YF F +LST+G  D
Sbjct: 199 LFSHMEG-WSYTEGFYFAFITLSTVGFGD 226


>gi|15718767 TRAAK [Homo sapiens]
          Length = 393

 Score = 90.9 bits (224), Expect = 1e-18
 Identities = 77/253 (30%), Positives = 120/253 (47%), Gaps = 23/253 (9%)

Query: 13  LVVAHLLALGLGAVVFQALEGPPACRLQAELRAELAAFQAEHRACLPP---GALEELLGT 69
           L+   LL L  GA+VF+ALE P   + Q EL      F   H  C+     G L + +  
Sbjct: 9   LLALVLLYLVSGALVFRALEQPHEQQAQRELGEVREKFLRAH-PCVSDQELGLLIKEVAD 67

Query: 70  ALATQAHGVSTLGNSSEGRTWDLPSALLFAASILTTTGYGHMAPLSPGGKAFCMVYAALG 129
           AL   A   +   ++S    WDL SA  F+ +I+TT GYG++A  +  G+ FC+ YA +G
Sbjct: 68  ALGGGADPETNSTSNSSHSAWDLGSAFFFSGTIITTIGYGNVALRTDAGRLFCIFYALVG 127

Query: 130 LPASLALVA--------TLRHCLLPVLSRPRAWVAVHWQLSPARAALLQAVALGLLVASS 181
           +P    L+A        +LRH +  + +     + + W + P    +L A+   L+    
Sbjct: 128 IPLFGILLAGVGDRLGSSLRHGIGHIEA-----IFLKWHVPPELVRVLSAMLFLLIGCLL 182

Query: 182 FVLLPALVLWGLQGDCSLLGAVYFCFSSLSTIGLEDLLPGR-----GRSLHPVIYHLGQL 236
           FVL P  V   ++ D S L A+YF   +L+T+G  D + G        +  P+++    L
Sbjct: 183 FVLTPTFVFCYME-DWSKLEAIYFVIVTLTTVGFGDYVAGADPRQDSPAYQPLVWFWILL 241

Query: 237 ALLGKSSHLTACG 249
            L   +S LT  G
Sbjct: 242 GLAYFASVLTTIG 254


>gi|11641275 potassium family, subfamily K, member 15 [Homo sapiens]
          Length = 330

 Score = 87.4 bits (215), Expect = 1e-17
 Identities = 72/225 (32%), Positives = 99/225 (44%), Gaps = 31/225 (13%)

Query: 5   RPWSRYGLLVVAHLLALGLGAVVFQALEGPPAC---RLQAELRAELA---AFQAEHRACL 58
           RP  R   LV+  L  L +GA VF ALE        RL  + R  L     F AE     
Sbjct: 3   RPSVRAAGLVLCTLCYLLVGAAVFDALESEAESGRQRLLVQKRGALRRKFGFSAED---- 58

Query: 59  PPGALEELLGTALATQAHGVSTLGNSSEGRTWDLPSALLFAASILTTTGYGHMAPLSPGG 118
                 EL   AL  + H          GR W  P +  FA +++TT GYGH AP +  G
Sbjct: 59  ----YRELERLALQAEPHRA--------GRQWKFPGSFYFAITVITTIGYGHAAPGTDSG 106

Query: 119 KAFCMVYAALGLPASLALVATLRHCLLPVLSR----PRAWVAVHWQLSPARAALLQAVAL 174
           K FCM YA LG+P +L    +L   L  V+ R     +  + + W       +    V  
Sbjct: 107 KVFCMFYALLGIPLTLVTFQSLGERLNAVVRRLLLAAKCCLGLRWTC----VSTENLVVA 162

Query: 175 GLLVASSFVLLPALVLWGLQGDCSLLGAVYFCFSSLSTIGLEDLL 219
           GLL  ++ + L A+     +G  +   A Y+CF +L+TIG  D +
Sbjct: 163 GLLACAATLALGAVAFSHFEG-WTFFHAYYYCFITLTTIGFGDFV 206


>gi|4504849 potassium channel, subfamily K, member 3 [Homo sapiens]
          Length = 394

 Score = 83.6 bits (205), Expect = 2e-16
 Identities = 62/205 (30%), Positives = 89/205 (43%), Gaps = 11/205 (5%)

Query: 13  LVVAHLLALGLGAVVFQALEGPPACRLQAELRAELAAFQAEHRACLPPGALEELLGTALA 72
           L+V     L +GA VF ALE  P   L    R EL   +   R  L  G  EEL    L 
Sbjct: 11  LIVCTFTYLLVGAAVFDALESEP--ELIERQRLELRQQELRARYNLSQGGYEELERVVLR 68

Query: 73  TQAHGVSTLGNSSEGRTWDLPSALLFAASILTTTGYGHMAPLSPGGKAFCMVYAALGLPA 132
            + H          G  W    +  FA +++TT GYGH AP + GGK FCM YA LG+P 
Sbjct: 69  LKPH--------KAGVQWRFAGSFYFAITVITTIGYGHAAPSTDGGKVFCMFYALLGIPL 120

Query: 133 SLALVATLRHCLLPVLSRPRAWVAVHWQLSPARAALLQAVALGLLVASSFVLLPALVLWG 192
           +L +  +L   +  ++            +  A  ++   V +G     S + + A     
Sbjct: 121 TLVMFQSLGERINTLVRYLLHRAKKGLGMRRADVSMANMVLIGFFSCISTLCIGAAAFSH 180

Query: 193 LQGDCSLLGAVYFCFSSLSTIGLED 217
            +   +   A Y+CF +L+TIG  D
Sbjct: 181 YE-HWTFFQAYYYCFITLTTIGFGD 204


>gi|4504851 potassium channel, subfamily K, member 5 [Homo sapiens]
          Length = 499

 Score = 80.9 bits (198), Expect = 1e-15
 Identities = 56/210 (26%), Positives = 99/210 (47%), Gaps = 4/210 (1%)

Query: 12  LLVVAHLLALGLGAVVFQALEGPPACRLQAELRAELAAFQAEHRACLPPGALEELLGTAL 71
           LL  A +  L +GA +F+ LE P     +     +      E   CL    L+++L    
Sbjct: 7   LLTSAIIFYLAIGAAIFEVLEEPHWKEAKKNYYTQKLHLLKEF-PCLGQEGLDKILEVVS 65

Query: 72  ATQAHGVSTLGNSSEGRTWDLPSALLFAASILTTTGYGHMAPLSPGGKAFCMVYAALGLP 131
                GV+  GN +    W+ P+A++FAA+++TT GYG++AP +P G+ FC+ Y   G+P
Sbjct: 66  DAAGQGVAITGNQTFNN-WNWPNAMIFAATVITTIGYGNVAPKTPAGRLFCVFYGLFGVP 124

Query: 132 ASLALVATLRHCLLPVLSRPRAWVAVHWQLSPARAALLQAVALGLLVASSFVLLPALVLW 191
             L  ++ L         R   ++     +S  +A +   V   +      +++P  V  
Sbjct: 125 LCLTWISALGKFFGGRAKRLGQFLTKR-GVSLRKAQITCTVIFIVWGVLVHLVIPPFVFM 183

Query: 192 GLQGDCSLLGAVYFCFSSLSTIGLEDLLPG 221
             +G  + +  +Y+ F ++STIG  D + G
Sbjct: 184 VTEG-WNYIEGLYYSFITISTIGFGDFVAG 212


>gi|7706135 potassium channel, subfamily K, member 9 [Homo sapiens]
          Length = 374

 Score = 75.1 bits (183), Expect = 6e-14
 Identities = 56/205 (27%), Positives = 90/205 (43%), Gaps = 11/205 (5%)

Query: 13  LVVAHLLALGLGAVVFQALEGPPACRLQAELRAELAAFQAEHRACLPPGALEELLGTALA 72
           L+V     L +GA VF ALE     R + +L+AE    + ++          EL+   L 
Sbjct: 11  LIVCTFTYLLVGAAVFDALESDHEMREEEKLKAEEIRIKGKYNISSEDYRQLELV--ILQ 68

Query: 73  TQAHGVSTLGNSSEGRTWDLPSALLFAASILTTTGYGHMAPLSPGGKAFCMVYAALGLPA 132
           ++ H          G  W    +  FA +++TT GYGH AP +  GKAFCM YA LG+P 
Sbjct: 69  SEPHRA--------GVQWKFAGSFYFAITVITTIGYGHAAPGTDAGKAFCMFYAVLGIPL 120

Query: 133 SLALVATLRHCLLPVLSRPRAWVAVHWQLSPARAALLQAVALGLLVASSFVLLPALVLWG 192
           +L +  +L   +   +      +     +     ++   V +G       + + A     
Sbjct: 121 TLVMFQSLGERMNTFVRYLLKRIKKCCGMRNTDVSMENMVTVGFFSCMGTLCIGAAAFSQ 180

Query: 193 LQGDCSLLGAVYFCFSSLSTIGLED 217
            + + S   A Y+CF +L+TIG  D
Sbjct: 181 CE-EWSFFHAYYYCFITLTTIGFGD 204


>gi|11545761 potassium channel, subfamily K, member 12 [Homo
           sapiens]
          Length = 430

 Score = 69.3 bits (168), Expect = 3e-12
 Identities = 69/258 (26%), Positives = 99/258 (38%), Gaps = 38/258 (14%)

Query: 9   RYGLLVVAHLLALGLGAVVFQALEGPPACRLQAELRAELAAFQAEHRACLPPGALEELLG 68
           R+ LL     L L  GA VF ALE P     +A   A L  F A H    P   L   L 
Sbjct: 38  RFVLLAALIGLYLVAGATVFSALESPGEAEARARWGATLRNFSAAHGVAEPE--LRAFLR 95

Query: 69  TALATQAHGVSTLGNSSEGRTWDLPSALLFAASILTTTGYGHMAPLSPGGKAFCMVYAAL 128
              A  A GV      +    WD P A  F  ++++T G+G   P + GGKAF + Y   
Sbjct: 96  HYEAALAAGVRA---DALRPRWDFPGAFYFVGTVVSTIGFGMTTPATVGGKAFLIAYGLF 152

Query: 129 GLPASL------------ALVATLRHC---------LLPVLSR-----PRAWVAVHWQLS 162
           G   ++             L   +R C         LLP   R       A     W+ S
Sbjct: 153 GCAGTILFFNLFLERIISLLAFIMRACRERQLRRSGLLPATFRRGSALSEADSLAGWKPS 212

Query: 163 PARAALLQAVALGLLVASSFVLLPALVLWGLQGDCSLLGAVYFCFSSLSTIGLEDLLPGR 222
                L+  +   LL   +  +  ++  W        + ++YFCF + STIG  DL+  +
Sbjct: 213 VYHVLLILGLFAVLLSCCASAMYTSVEGW------DYVDSLYFCFVTFSTIGFGDLVSSQ 266

Query: 223 GRSL-HPVIYHLGQLALL 239
             +  +  +Y LG    +
Sbjct: 267 HAAYRNQGLYRLGNFLFI 284


>gi|16306555 potassium channel, subfamily K, member 13 [Homo
           sapiens]
          Length = 408

 Score = 53.9 bits (128), Expect = 1e-07
 Identities = 56/234 (23%), Positives = 91/234 (38%), Gaps = 29/234 (12%)

Query: 8   SRYGLLVVAHLLALGLGAVVFQALEGPPACRLQAELRAELAAFQAEHRACLPPGALEELL 67
           +R+ LL    +L L  GA VF ALE     + +      LA F   H       + +EL 
Sbjct: 18  ARFLLLAALIVLYLLGGAAVFSALELAHERQAKQRWEERLANFSRGHNL-----SRDELR 72

Query: 68  GTALATQAHGVSTLGNSSEGRTWDLPSALLFAASILTTTGYGHMAPLSPGGKAFCMVYAA 127
           G     +    + +   +    WD   A  F  ++++T G+G   P + GGK F + Y  
Sbjct: 73  GFLRHYEEATRAGIRVDNVRPRWDFTGAFYFVGTVVSTIGFGMTTPATVGGKIFLIFYGL 132

Query: 128 LGLPASLALVATLRHCLLPVLSRPRAWVAVHWQLSPARAALLQA---------------- 171
           +G  +++         L+ +++      + H +    R AL Q                 
Sbjct: 133 VGCSSTILFFNLFLERLITIIA--YIMKSCHQRQLRRRGALPQESLKDAGQCEVDSLAGW 190

Query: 172 ------VALGLLVASSFVLLPALVLWGLQGDCSLLGAVYFCFSSLSTIGLEDLL 219
                 V L L  AS  +   A  ++      S   ++YFCF + STIG  DL+
Sbjct: 191 KPSVYYVMLILCTASILISCCASAMYTPIEGWSYFDSLYFCFVAFSTIGFGDLV 244


>gi|32469495 potassium channel, subfamily K, member 18 [Homo
           sapiens]
          Length = 384

 Score = 47.4 bits (111), Expect = 1e-05
 Identities = 20/60 (33%), Positives = 33/60 (55%)

Query: 90  WDLPSALLFAASILTTTGYGHMAPLSPGGKAFCMVYAALGLPASLALVATLRHCLLPVLS 149
           W   S+L F  ++ +T GYG++ P++  GK  CM+YA  G+P    ++      L  +LS
Sbjct: 101 WSFLSSLFFCCTVFSTVGYGYIYPVTRLGKYLCMLYALFGIPLMFLVLTDTGDILATILS 160


>gi|170650615 protoporphyrinogen oxidase [Homo sapiens]
          Length = 477

 Score = 36.2 bits (82), Expect = 0.029
 Identities = 37/133 (27%), Positives = 57/133 (42%), Gaps = 13/133 (9%)

Query: 7   WS-RYGLLVVAHLLALGLGAVVFQALEGPPAC--RLQAELRAELA----AFQAEHR-ACL 58
           WS R GL ++   L   L +     L G P C   LQAE R +++    + +A+H  + +
Sbjct: 227 WSLRGGLEMLPQALETHLTSRGVSVLRGQPVCGLSLQAEGRWKVSLRDSSLEADHVISAI 286

Query: 59  PPGALEELLGTALATQAHGVSTLGNSSEGRTWDLPSALLFAASILTTTGYGHMAPLSPGG 118
           P   L ELL    A  A  +S +   S          L +  + L   G+GH+ P S   
Sbjct: 287 PASVLSELLPAEAAPLARALSAITAVSVAVV-----NLQYQGAHLPVQGFGHLVPSSEDP 341

Query: 119 KAFCMVYAALGLP 131
               +VY ++  P
Sbjct: 342 GVLGIVYDSVAFP 354


>gi|4506001 protoporphyrinogen oxidase [Homo sapiens]
          Length = 477

 Score = 36.2 bits (82), Expect = 0.029
 Identities = 37/133 (27%), Positives = 57/133 (42%), Gaps = 13/133 (9%)

Query: 7   WS-RYGLLVVAHLLALGLGAVVFQALEGPPAC--RLQAELRAELA----AFQAEHR-ACL 58
           WS R GL ++   L   L +     L G P C   LQAE R +++    + +A+H  + +
Sbjct: 227 WSLRGGLEMLPQALETHLTSRGVSVLRGQPVCGLSLQAEGRWKVSLRDSSLEADHVISAI 286

Query: 59  PPGALEELLGTALATQAHGVSTLGNSSEGRTWDLPSALLFAASILTTTGYGHMAPLSPGG 118
           P   L ELL    A  A  +S +   S          L +  + L   G+GH+ P S   
Sbjct: 287 PASVLSELLPAEAAPLARALSAITAVSVAVV-----NLQYQGAHLPVQGFGHLVPSSEDP 341

Query: 119 KAFCMVYAALGLP 131
               +VY ++  P
Sbjct: 342 GVLGIVYDSVAFP 354


>gi|5031819 potassium voltage-gated channel, shaker-related
           subfamily, member 10 [Homo sapiens]
          Length = 511

 Score = 34.3 bits (77), Expect = 0.11
 Identities = 15/39 (38%), Positives = 21/39 (53%)

Query: 92  LPSALLFAASILTTTGYGHMAPLSPGGKAFCMVYAALGL 130
           +P    +A   +TT GYG M P +PGGK    + A  G+
Sbjct: 408 IPDGFWWAVVTMTTVGYGDMCPTTPGGKIVGTLCAIAGV 446


>gi|25952092 potassium voltage-gated channel, shaker-related
           subfamily, member 7 [Homo sapiens]
          Length = 456

 Score = 33.5 bits (75), Expect = 0.19
 Identities = 15/39 (38%), Positives = 23/39 (58%)

Query: 92  LPSALLFAASILTTTGYGHMAPLSPGGKAFCMVYAALGL 130
           +P +  +A   +TT GYG MAP++ GGK    + A  G+
Sbjct: 345 IPESFWWAVVTMTTVGYGDMAPVTVGGKIVGSLCAIAGV 383


  Database: hs.faa
    Posted date:  Aug 4, 2009  4:42 PM
  Number of letters in database: 18,247,518
  Number of sequences in database:  37,866
  
Lambda     K      H
   0.324    0.138    0.432 

Gapped
Lambda     K      H
   0.267   0.0410    0.140 


Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Hits to DB: 10,495,452
Number of Sequences: 37866
Number of extensions: 465312
Number of successful extensions: 1588
Number of sequences better than 10.0: 30
Number of HSP's better than 10.0 without gapping: 45
Number of HSP's successfully gapped in prelim test: 20
Number of HSP's that attempted gapping in prelim test: 1468
Number of HSP's gapped (non-prelim): 81
length of query: 257
length of database: 18,247,518
effective HSP length: 100
effective length of query: 157
effective length of database: 14,460,918
effective search space: 2270364126
effective search space used: 2270364126
T: 11
A: 40
X1: 15 ( 7.0 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 40 (21.5 bits)
S2: 61 (28.1 bits)

Search results were obtained with NCBI BLAST and RefSeq entries.


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Guide to the Human Genome
Copyright © 2010 by Stewart Scherer. All rights reserved.

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