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Search of human proteins with 5031819
BLASTP 2.2.11 [Jun-05-2005]
Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer,
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997),
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs", Nucleic Acids Res. 25:3389-3402.
Query= gi|5031819 potassium voltage-gated channel, shaker-related
subfamily, member 10 [Homo sapiens]
(511 letters)
Database: hs.faa
37,866 sequences; 18,247,518 total letters
Searching..................................................done
Score E
Sequences producing significant alignments: (bits) Value
gi|5031819 potassium voltage-gated channel, shaker-related subfa... 1023 0.0
gi|119395748 potassium voltage-gated channel subfamily A member ... 582 e-166
gi|4826782 potassium voltage-gated channel, shaker-related subfa... 580 e-165
gi|88758565 potassium voltage-gated channel, shaker-related subf... 577 e-165
gi|4504817 potassium voltage-gated channel, shaker-related subfa... 570 e-162
gi|25952087 potassium voltage-gated channel, shaker-related subf... 566 e-161
gi|4504821 potassium voltage-gated channel, shaker-related subfa... 544 e-155
gi|25952092 potassium voltage-gated channel, shaker-related subf... 528 e-150
gi|27436974 potassium voltage-gated channel, Shab-related subfam... 280 2e-75
gi|4826784 potassium voltage-gated channel, Shab-related subfami... 270 2e-72
gi|27436981 potassium voltage-gated channel, Shal-related subfam... 269 5e-72
gi|4826786 Shaw-related voltage-gated potassium channel protein ... 263 4e-70
gi|163792201 Shaw-related voltage-gated potassium channel protei... 263 4e-70
gi|88758576 Shaw-related voltage-gated potassium channel protein... 260 2e-69
gi|24497462 Shaw-related voltage-gated potassium channel protein... 260 2e-69
gi|24497464 Shaw-related voltage-gated potassium channel protein... 260 2e-69
gi|27436984 potassium voltage-gated channel, Shal-related subfam... 259 3e-69
gi|27436986 potassium voltage-gated channel, Shal-related subfam... 259 3e-69
gi|21217561 Shaw-related voltage-gated potassium channel protein... 257 2e-68
gi|21217563 Shaw-related voltage-gated potassium channel protein... 257 2e-68
gi|24497458 Shaw-related voltage-gated potassium channel protein... 257 2e-68
gi|9789987 potassium voltage-gated channel, Shal-related subfami... 256 3e-68
gi|45383011 potassium voltage-gated channel, delayed-rectifier, ... 247 2e-65
gi|24497460 Shaw-related voltage-gated potassium channel protein... 234 1e-61
gi|25952108 potassium voltage-gated channel delayed-rectifier pr... 227 2e-59
gi|13492973 potassium voltage-gated channel delayed-rectifier pr... 224 2e-58
gi|20070166 potassium voltage-gated channel, subfamily F, member... 219 6e-57
gi|7657289 potassium channel, subfamily V, member 1 [Homo sapiens] 214 2e-55
gi|19071574 potassium voltage-gated channel, subfamily G, member... 211 1e-54
gi|27436993 potassium voltage-gated channel, subfamily G, member... 208 1e-53
>gi|5031819 potassium voltage-gated channel, shaker-related
subfamily, member 10 [Homo sapiens]
Length = 511
Score = 1023 bits (2646), Expect = 0.0
Identities = 511/511 (100%), Positives = 511/511 (100%)
Query: 1 MDVCGWKEMEVALVNFDNSDEIQEEPGYATDFDSTSPKGRPGGSSFSNGKILISESTNHE 60
MDVCGWKEMEVALVNFDNSDEIQEEPGYATDFDSTSPKGRPGGSSFSNGKILISESTNHE
Sbjct: 1 MDVCGWKEMEVALVNFDNSDEIQEEPGYATDFDSTSPKGRPGGSSFSNGKILISESTNHE 60
Query: 61 TAFSKLPGDYADPPGPEPVVLNEGNQRVIINIAGLRFETQLRTLSQFPETLLGDREKRMQ 120
TAFSKLPGDYADPPGPEPVVLNEGNQRVIINIAGLRFETQLRTLSQFPETLLGDREKRMQ
Sbjct: 61 TAFSKLPGDYADPPGPEPVVLNEGNQRVIINIAGLRFETQLRTLSQFPETLLGDREKRMQ 120
Query: 121 FFDSMRNEYFFDRNRPSFDGILYYYQSGGKIRRPANVPIDIFADEISFYELGSEAMDQFR 180
FFDSMRNEYFFDRNRPSFDGILYYYQSGGKIRRPANVPIDIFADEISFYELGSEAMDQFR
Sbjct: 121 FFDSMRNEYFFDRNRPSFDGILYYYQSGGKIRRPANVPIDIFADEISFYELGSEAMDQFR 180
Query: 181 EDEGFIKDPETLLPTNDIHRQFWLLFEYPESSSAARAVAVVSVLVVVISITIFCLETLPE 240
EDEGFIKDPETLLPTNDIHRQFWLLFEYPESSSAARAVAVVSVLVVVISITIFCLETLPE
Sbjct: 181 EDEGFIKDPETLLPTNDIHRQFWLLFEYPESSSAARAVAVVSVLVVVISITIFCLETLPE 240
Query: 241 FREDRELKVVRDPNLNMSKTVLSQTMFTDPFFMVESTCIVWFTFELVLRFVVCPSKTDFF 300
FREDRELKVVRDPNLNMSKTVLSQTMFTDPFFMVESTCIVWFTFELVLRFVVCPSKTDFF
Sbjct: 241 FREDRELKVVRDPNLNMSKTVLSQTMFTDPFFMVESTCIVWFTFELVLRFVVCPSKTDFF 300
Query: 301 RNIMNIIDIISIIPYFATLITELVQETEPSAQQNMSLAILRIIRLVRVFRIFKLSRHSKG 360
RNIMNIIDIISIIPYFATLITELVQETEPSAQQNMSLAILRIIRLVRVFRIFKLSRHSKG
Sbjct: 301 RNIMNIIDIISIIPYFATLITELVQETEPSAQQNMSLAILRIIRLVRVFRIFKLSRHSKG 360
Query: 361 LQILGQTLKASMRELGLLIFFLFIGVILFSSAVYFAEVDEPESHFSSIPDGFWWAVVTMT 420
LQILGQTLKASMRELGLLIFFLFIGVILFSSAVYFAEVDEPESHFSSIPDGFWWAVVTMT
Sbjct: 361 LQILGQTLKASMRELGLLIFFLFIGVILFSSAVYFAEVDEPESHFSSIPDGFWWAVVTMT 420
Query: 421 TVGYGDMCPTTPGGKIVGTLCAIAGVLTIALPVPVIVSNFNYFYHRETENEEKQNIPGEI 480
TVGYGDMCPTTPGGKIVGTLCAIAGVLTIALPVPVIVSNFNYFYHRETENEEKQNIPGEI
Sbjct: 421 TVGYGDMCPTTPGGKIVGTLCAIAGVLTIALPVPVIVSNFNYFYHRETENEEKQNIPGEI 480
Query: 481 ERILNSVGSRMGSTDSLNKTNGGCSTEKSRK 511
ERILNSVGSRMGSTDSLNKTNGGCSTEKSRK
Sbjct: 481 ERILNSVGSRMGSTDSLNKTNGGCSTEKSRK 511
>gi|119395748 potassium voltage-gated channel subfamily A member 1
[Homo sapiens]
Length = 495
Score = 582 bits (1501), Expect = e-166
Identities = 283/392 (72%), Positives = 334/392 (85%), Gaps = 2/392 (0%)
Query: 86 QRVIINIAGLRFETQLRTLSQFPETLLGDREKRMQFFDSMRNEYFFDRNRPSFDGILYYY 145
+RV+INI+GLRFETQL+TL+QFP TLLG+ +KRM++FD +RNEYFFDRNRPSFD ILYYY
Sbjct: 37 ERVVINISGLRFETQLKTLAQFPNTLLGNPKKRMRYFDPLRNEYFFDRNRPSFDAILYYY 96
Query: 146 QSGGKIRRPANVPIDIFADEISFYELGSEAMDQFREDEGFIKDPETLLPTNDIHRQFWLL 205
QSGG++RRP NVP+D+F++EI FYELG EAM++FREDEGFIK+ E LP + RQ WLL
Sbjct: 97 QSGGRLRRPVNVPLDMFSEEIKFYELGEEAMEKFREDEGFIKEEERPLPEKEYQRQVWLL 156
Query: 206 FEYPESSSAARAVAVVSVLVVVISITIFCLETLPEFREDRELKVVRDPNLNMSKTVLSQT 265
FEYPESS AR +A+VSV+V++ISI IFCLETLPE ++D++ ++ + + +
Sbjct: 157 FEYPESSGPARVIAIVSVMVILISIVIFCLETLPELKDDKDFTGTVH-RIDNTTVIYNSN 215
Query: 266 MFTDPFFMVESTCIVWFTFELVLRFVVCPSKTDFFRNIMNIIDIISIIPYFATLITELV- 324
+FTDPFF+VE+ CI+WF+FELV+RF CPSKTDFF+NIMN IDI++IIPYF TL TE+
Sbjct: 216 IFTDPFFIVETLCIIWFSFELVVRFFACPSKTDFFKNIMNFIDIVAIIPYFITLGTEIAE 275
Query: 325 QETEPSAQQNMSLAILRIIRLVRVFRIFKLSRHSKGLQILGQTLKASMRELGLLIFFLFI 384
QE +Q SLAILR+IRLVRVFRIFKLSRHSKGLQILGQTLKASMRELGLLIFFLFI
Sbjct: 276 QEGNQKGEQATSLAILRVIRLVRVFRIFKLSRHSKGLQILGQTLKASMRELGLLIFFLFI 335
Query: 385 GVILFSSAVYFAEVDEPESHFSSIPDGFWWAVVTMTTVGYGDMCPTTPGGKIVGTLCAIA 444
GVILFSSAVYFAE +E ESHFSSIPD FWWAVV+MTTVGYGDM P T GGKIVG+LCAIA
Sbjct: 336 GVILFSSAVYFAEAEEAESHFSSIPDAFWWAVVSMTTVGYGDMYPVTIGGKIVGSLCAIA 395
Query: 445 GVLTIALPVPVIVSNFNYFYHRETENEEKQNI 476
GVLTIALPVPVIVSNFNYFYHRETE EE+ +
Sbjct: 396 GVLTIALPVPVIVSNFNYFYHRETEGEEQAQL 427
>gi|4826782 potassium voltage-gated channel, shaker-related
subfamily, member 2 [Homo sapiens]
Length = 499
Score = 580 bits (1495), Expect = e-165
Identities = 295/414 (71%), Positives = 337/414 (81%), Gaps = 8/414 (1%)
Query: 66 LPGDYADPPGPEPVVLNEGNQRVIINIAGLRFETQLRTLSQFPETLLGDREKRMQFFDSM 125
LPG D PE +E +RV+INI+GLRFETQL+TL+QFPETLLGD +KRM++FD +
Sbjct: 15 LPGHPQDTYDPEAD--HECCERVVINISGLRFETQLKTLAQFPETLLGDPKKRMRYFDPL 72
Query: 126 RNEYFFDRNRPSFDGILYYYQSGGKIRRPANVPIDIFADEISFYELGSEAMDQFREDEGF 185
RNEYFFDRNRPSFD ILYYYQSGG++RRP NVP+DIF++EI FYELG EAM+ FREDEG+
Sbjct: 73 RNEYFFDRNRPSFDAILYYYQSGGRLRRPVNVPLDIFSEEIRFYELGEEAMEMFREDEGY 132
Query: 186 IKDPETLLPTNDIHRQFWLLFEYPESSSAARAVAVVSVLVVVISITIFCLETLPEFREDR 245
IK+ E LP N+ RQ WLLFEYPESS AR +A+VSV+V++ISI FCLETLP FR++
Sbjct: 133 IKEEERPLPENEFQRQVWLLFEYPESSGPARIIAIVSVMVILISIVSFCLETLPIFRDEN 192
Query: 246 E----LKVVRDPNLNMSKTVLSQTMFTDPFFMVESTCIVWFTFELVLRFVVCPSKTDFFR 301
E V N + T FTDPFF+VE+ CI+WF+FE ++RF CPSK FF
Sbjct: 193 EDMHGSGVTFHTYSNSTIGYQQSTSFTDPFFIVETLCIIWFSFEFLVRFFACPSKAGFFT 252
Query: 302 NIMNIIDIISIIPYFATLITELVQETEPS--AQQNMSLAILRIIRLVRVFRIFKLSRHSK 359
NIMNIIDI++IIPYF TL TEL ++ E + QQ MSLAILR+IRLVRVFRIFKLSRHSK
Sbjct: 253 NIMNIIDIVAIIPYFITLGTELAEKPEDAQQGQQAMSLAILRVIRLVRVFRIFKLSRHSK 312
Query: 360 GLQILGQTLKASMRELGLLIFFLFIGVILFSSAVYFAEVDEPESHFSSIPDGFWWAVVTM 419
GLQILGQTLKASMRELGLLIFFLFIGVILFSSAVYFAE DE ES F SIPD FWWAVV+M
Sbjct: 313 GLQILGQTLKASMRELGLLIFFLFIGVILFSSAVYFAEADERESQFPSIPDAFWWAVVSM 372
Query: 420 TTVGYGDMCPTTPGGKIVGTLCAIAGVLTIALPVPVIVSNFNYFYHRETENEEK 473
TTVGYGDM PTT GGKIVG+LCAIAGVLTIALPVPVIVSNFNYFYHRETE EE+
Sbjct: 373 TTVGYGDMVPTTIGGKIVGSLCAIAGVLTIALPVPVIVSNFNYFYHRETEGEEQ 426
>gi|88758565 potassium voltage-gated channel, shaker-related
subfamily, member 3 [Homo sapiens]
Length = 575
Score = 577 bits (1487), Expect = e-165
Identities = 286/394 (72%), Positives = 332/394 (84%), Gaps = 7/394 (1%)
Query: 86 QRVIINIAGLRFETQLRTLSQFPETLLGDREKRMQFFDSMRNEYFFDRNRPSFDGILYYY 145
+RV+INI+GLRFETQL+TL QFPETLLGD ++RM++FD +RNEYFFDRNRPSFD ILYYY
Sbjct: 104 ERVVINISGLRFETQLKTLCQFPETLLGDPKRRMRYFDPLRNEYFFDRNRPSFDAILYYY 163
Query: 146 QSGGKIRRPANVPIDIFADEISFYELGSEAMDQFREDEGFIKDPETLLPTNDIHRQFWLL 205
QSGG+IRRP NVPIDIF++EI FY+LG EAM++FREDEGF+++ E LP D RQ WLL
Sbjct: 164 QSGGRIRRPVNVPIDIFSEEIRFYQLGEEAMEKFREDEGFLREEERPLPRRDFQRQVWLL 223
Query: 206 FEYPESSSAARAVAVVSVLVVVISITIFCLETLPEFREDRELKVVRDPNL------NMSK 259
FEYPESS AR +A+VSVLV++ISI IFCLETLPEFR++++ + + S
Sbjct: 224 FEYPESSGPARGIAIVSVLVILISIVIFCLETLPEFRDEKDYPASTSQDSFEAAGNSTSG 283
Query: 260 TVLSQTMFTDPFFMVESTCIVWFTFELVLRFVVCPSKTDFFRNIMNIIDIISIIPYFATL 319
+ + F+DPFF+VE+ CI+WF+FEL++RF CPSK F RNIMN+IDI++IIPYF TL
Sbjct: 284 SRAGASSFSDPFFVVETLCIIWFSFELLVRFFACPSKATFSRNIMNLIDIVAIIPYFITL 343
Query: 320 ITELVQETEPSAQQNMSLAILRIIRLVRVFRIFKLSRHSKGLQILGQTLKASMRELGLLI 379
TEL E + + QQ MSLAILR+IRLVRVFRIFKLSRHSKGLQILGQTLKASMRELGLLI
Sbjct: 344 GTELA-ERQGNGQQAMSLAILRVIRLVRVFRIFKLSRHSKGLQILGQTLKASMRELGLLI 402
Query: 380 FFLFIGVILFSSAVYFAEVDEPESHFSSIPDGFWWAVVTMTTVGYGDMCPTTPGGKIVGT 439
FFLFIGVILFSSAVYFAE D+P S FSSIPD FWWAVVTMTTVGYGDM P T GGKIVG+
Sbjct: 403 FFLFIGVILFSSAVYFAEADDPTSGFSSIPDAFWWAVVTMTTVGYGDMHPVTIGGKIVGS 462
Query: 440 LCAIAGVLTIALPVPVIVSNFNYFYHRETENEEK 473
LCAIAGVLTIALPVPVIVSNFNYFYHRETE EE+
Sbjct: 463 LCAIAGVLTIALPVPVIVSNFNYFYHRETEGEEQ 496
>gi|4504817 potassium voltage-gated channel, shaker-related
subfamily, member 4 [Homo sapiens]
Length = 653
Score = 570 bits (1469), Expect = e-162
Identities = 285/408 (69%), Positives = 331/408 (81%), Gaps = 21/408 (5%)
Query: 86 QRVIINIAGLRFETQLRTLSQFPETLLGDREKRMQFFDSMRNEYFFDRNRPSFDGILYYY 145
+RV+IN++GLRFETQ++TL+QFPETLLGD EKR Q+FD +RNEYFFDRNRPSFD ILYYY
Sbjct: 176 ERVVINVSGLRFETQMKTLAQFPETLLGDPEKRTQYFDPLRNEYFFDRNRPSFDAILYYY 235
Query: 146 QSGGKIRRPANVPIDIFADEISFYELGSEAMDQFREDEGFIKDPET-LLPTNDIHRQFWL 204
QSGG+++RP NVP DIF +E+ FY+LG EA+ +FREDEGF+++ E LP N+ +Q WL
Sbjct: 236 QSGGRLKRPVNVPFDIFTEEVKFYQLGEEALLKFREDEGFVREEEDRALPENEFKKQIWL 295
Query: 205 LFEYPESSSAARAVAVVSVLVVVISITIFCLETLPEFREDRELKVVRD------------ 252
LFEYPESSS AR +A+VSVLV++ISI IFCLETLPEFR+DR+L +
Sbjct: 296 LFEYPESSSPARGIAIVSVLVILISIVIFCLETLPEFRDDRDLVMALSAGGHGGLLNDTS 355
Query: 253 -PNLNMSKTVLSQTMFTDPFFMVESTCIVWFTFELVLRFVVCPSKTDFFRNIMNIIDIIS 311
P+L S T+F DPFF+VE+ CIVWF+FE V+R CPS+ FF+NIMNIIDI+S
Sbjct: 356 APHLENS----GHTIFNDPFFIVETVCIVWFSFEFVVRCFACPSQALFFKNIMNIIDIVS 411
Query: 312 IIPYFATLITELVQET---EPSAQQNMSLAILRIIRLVRVFRIFKLSRHSKGLQILGQTL 368
I+PYF TL T+L Q+ QQ MS AILRIIRLVRVFRIFKLSRHSKGLQILG TL
Sbjct: 412 ILPYFITLGTDLAQQQGGGNGQQQQAMSFAILRIIRLVRVFRIFKLSRHSKGLQILGHTL 471
Query: 369 KASMRELGLLIFFLFIGVILFSSAVYFAEVDEPESHFSSIPDGFWWAVVTMTTVGYGDMC 428
+ASMRELGLLIFFLFIGVILFSSAVYFAE DEP +HF SIPD FWWAVVTMTTVGYGDM
Sbjct: 472 RASMRELGLLIFFLFIGVILFSSAVYFAEADEPTTHFQSIPDAFWWAVVTMTTVGYGDMK 531
Query: 429 PTTPGGKIVGTLCAIAGVLTIALPVPVIVSNFNYFYHRETENEEKQNI 476
P T GGKIVG+LCAIAGVLTIALPVPVIVSNFNYFYHRETENEE+ +
Sbjct: 532 PITVGGKIVGSLCAIAGVLTIALPVPVIVSNFNYFYHRETENEEQTQL 579
>gi|25952087 potassium voltage-gated channel, shaker-related
subfamily, member 5 [Homo sapiens]
Length = 613
Score = 567 bits (1460), Expect = e-161
Identities = 286/414 (69%), Positives = 334/414 (80%), Gaps = 27/414 (6%)
Query: 85 NQRVIINIAGLRFETQLRTLSQFPETLLGDREKRMQFFDSMRNEYFFDRNRPSFDGILYY 144
+QRV INI+GLRFETQL TL+QFP TLLGD KR+++FD +RNEYFFDRNRPSFDGILYY
Sbjct: 119 HQRVHINISGLRFETQLGTLAQFPNTLLGDPAKRLRYFDPLRNEYFFDRNRPSFDGILYY 178
Query: 145 YQSGGKIRRPANVPIDIFADEISFYELGSEAMDQFREDEGFIKDPETLLPTNDIHRQFWL 204
YQSGG++RRP NV +D+FADEI FY+LG EAM++FREDEGFIK+ E LP N+ RQ WL
Sbjct: 179 YQSGGRLRRPVNVSLDVFADEIRFYQLGDEAMERFREDEGFIKEEEKPLPRNEFQRQVWL 238
Query: 205 LFEYPESSSAARAVAVVSVLVVVISITIFCLETLPEFREDREL----------------- 247
+FEYPESS +ARA+A+VSVLV++ISI FCLETLPEFR++REL
Sbjct: 239 IFEYPESSGSARAIAIVSVLVILISIITFCLETLPEFRDERELLRHPPAPHQPPAPAPGA 298
Query: 248 ---KVVRDPNLNMSKTVLSQTMFTDPFFMVESTCIVWFTFELVLRFVVCPSKTDFFRNIM 304
V+ P+ +L +T+ DPFF+VE+TC++WFTFEL++RF CPSK F RNIM
Sbjct: 299 NGSGVMAPPSGPTVAPLLPRTL-ADPFFIVETTCVIWFTFELLVRFFACPSKAGFSRNIM 357
Query: 305 NIIDIISIIPYFATLITELVQETE------PSAQQNMSLAILRIIRLVRVFRIFKLSRHS 358
NIID+++I PYF TL TEL ++ + QQ MSLAILR+IRLVRVFRIFKLSRHS
Sbjct: 358 NIIDVVAIFPYFITLGTELAEQQPGGGGGGQNGQQAMSLAILRVIRLVRVFRIFKLSRHS 417
Query: 359 KGLQILGQTLKASMRELGLLIFFLFIGVILFSSAVYFAEVDEPESHFSSIPDGFWWAVVT 418
KGLQILG+TL+ASMRELGLLIFFLFIGVILFSSAVYFAE D +HFSSIPD FWWAVVT
Sbjct: 418 KGLQILGKTLQASMRELGLLIFFLFIGVILFSSAVYFAEADNQGTHFSSIPDAFWWAVVT 477
Query: 419 MTTVGYGDMCPTTPGGKIVGTLCAIAGVLTIALPVPVIVSNFNYFYHRETENEE 472
MTTVGYGDM P T GGKIVG+LCAIAGVLTIALPVPVIVSNFNYFYHRET++EE
Sbjct: 478 MTTVGYGDMRPITVGGKIVGSLCAIAGVLTIALPVPVIVSNFNYFYHRETDHEE 531
>gi|4504821 potassium voltage-gated channel, shaker-related
subfamily, member 6 [Homo sapiens]
Length = 529
Score = 544 bits (1402), Expect = e-155
Identities = 284/435 (65%), Positives = 329/435 (75%), Gaps = 46/435 (10%)
Query: 85 NQRVIINIAGLRFETQLRTLSQFPETLLGDREKRMQFFDSMRNEYFFDRNRPSFDGILYY 144
++R++INI+GLRFETQLRTLS FP+TLLGD +R++FFD +RNEYFFDRNRPSFD ILYY
Sbjct: 40 SERLVINISGLRFETQLRTLSLFPDTLLGDPGRRVRFFDPLRNEYFFDRNRPSFDAILYY 99
Query: 145 YQSGGKIRRPANVPIDIFADEISFYELGSEAMDQFREDEGFIKD---PETLLPTNDIHRQ 201
YQSGG++RRP NVP+DIF +EI FY+LG EA+ FREDEG + + E LP+ RQ
Sbjct: 100 YQSGGRLRRPVNVPLDIFLEEIRFYQLGDEALAAFREDEGCLPEGGEDEKPLPSQPFQRQ 159
Query: 202 FWLLFEYPESSSAARAVAVVSVLVVVISITIFCLETLPEFRED----------------- 244
WLLFEYPESS AR +A+VSVLV++ISI IFCLETLP+FR D
Sbjct: 160 VWLLFEYPESSGPARGIAIVSVLVILISIVIFCLETLPQFRVDGRGGNNGGVSRVSPVSR 219
Query: 245 --RELKVVRDPNLNM---------------SKTVLSQTMFTDPFFMVESTCIVWFTFELV 287
+E + D + S + L + FTDPFF+VE+ CIVWFTFEL+
Sbjct: 220 GSQEEEEDEDDSYTFHHGITPGEMGTGGSSSLSTLGGSFFTDPFFLVETLCIVWFTFELL 279
Query: 288 LRFVVCPSKTDFFRNIMNIIDIISIIPYFATLITELVQETEP---------SAQQNMSLA 338
+RF CPSK FFRNIMNIID+++I PYF TL TELVQ+ E + QQ MSLA
Sbjct: 280 VRFSACPSKPAFFRNIMNIIDLVAIFPYFITLGTELVQQQEQQPASGGGGQNGQQAMSLA 339
Query: 339 ILRIIRLVRVFRIFKLSRHSKGLQILGQTLKASMRELGLLIFFLFIGVILFSSAVYFAEV 398
ILR+IRLVRVFRIFKLSRHSKGLQILG+TL+ASMRELGLLIFFLFIGVILFSSAVYFAE
Sbjct: 340 ILRVIRLVRVFRIFKLSRHSKGLQILGKTLQASMRELGLLIFFLFIGVILFSSAVYFAEA 399
Query: 399 DEPESHFSSIPDGFWWAVVTMTTVGYGDMCPTTPGGKIVGTLCAIAGVLTIALPVPVIVS 458
D+ +S F SIPD FWWAVVTMTTVGYGDM P T GGKIVG+LCAIAGVLTIALPVPVIVS
Sbjct: 400 DDDDSLFPSIPDAFWWAVVTMTTVGYGDMYPMTVGGKIVGSLCAIAGVLTIALPVPVIVS 459
Query: 459 NFNYFYHRETENEEK 473
NFNYFYHRETE EE+
Sbjct: 460 NFNYFYHRETEQEEQ 474
>gi|25952092 potassium voltage-gated channel, shaker-related
subfamily, member 7 [Homo sapiens]
Length = 456
Score = 528 bits (1360), Expect = e-150
Identities = 262/398 (65%), Positives = 320/398 (80%), Gaps = 12/398 (3%)
Query: 86 QRVIINIAGLRFETQLRTLSQFPETLLGDREKRMQFFDSMRNEYFFDRNRPSFDGILYYY 145
+R+++N+AGLRFET+ RTL +FP+TLLGD +R +F+D R EYFFDR+RPSFD +LYYY
Sbjct: 13 ERLVLNVAGLRFETRARTLGRFPDTLLGDPARRGRFYDDARREYFFDRHRPSFDAVLYYY 72
Query: 146 QSGGKIRRPANVPIDIFADEISFYELGSEAMDQFREDEGFIKDPETLLPTNDIHRQFWLL 205
QSGG++RRPA+VP+D+F +E++FY LG+ A+ + REDEG PE LP RQ WLL
Sbjct: 73 QSGGRLRRPAHVPLDVFLEEVAFYGLGAAALARLREDEGCPVPPERPLPRRAFARQLWLL 132
Query: 206 FEYPESSSAARAVAVVSVLVVVISITIFCLETLPEFREDRE-----LKVVRDP---NLNM 257
FE+PESS AAR +AVVSVLV+++SI +FCLETLP+FR+DR+ P LN
Sbjct: 133 FEFPESSQAARVLAVVSVLVILVSIVVFCLETLPDFRDDRDGTGLAAAAAAGPFPAPLNG 192
Query: 258 SKTVLS---QTMFTDPFFMVESTCIVWFTFELVLRFVVCPSKTDFFRNIMNIIDIISIIP 314
S + + F DPFF+VE+ CI WF+FEL++R +VCPSK FF+N+MN+ID ++I+P
Sbjct: 193 SSQMPGNPPRLPFNDPFFVVETLCICWFSFELLVRLLVCPSKAIFFKNVMNLIDFVAILP 252
Query: 315 YFATLITELVQETEPSAQQNMSLAILRIIRLVRVFRIFKLSRHSKGLQILGQTLKASMRE 374
YF L TEL ++ QQ MSLAILR+IRLVRVFRIFKLSRHSKGLQILGQTL+ASMRE
Sbjct: 253 YFVALGTELARQ-RGVGQQAMSLAILRVIRLVRVFRIFKLSRHSKGLQILGQTLRASMRE 311
Query: 375 LGLLIFFLFIGVILFSSAVYFAEVDEPESHFSSIPDGFWWAVVTMTTVGYGDMCPTTPGG 434
LGLLIFFLFIGV+LFSSAVYFAEVD +SHF+SIP+ FWWAVVTMTTVGYGDM P T GG
Sbjct: 312 LGLLIFFLFIGVVLFSSAVYFAEVDRVDSHFTSIPESFWWAVVTMTTVGYGDMAPVTVGG 371
Query: 435 KIVGTLCAIAGVLTIALPVPVIVSNFNYFYHRETENEE 472
KIVG+LCAIAGVLTI+LPVPVIVSNF+YFYHRETE EE
Sbjct: 372 KIVGSLCAIAGVLTISLPVPVIVSNFSYFYHRETEGEE 409
>gi|27436974 potassium voltage-gated channel, Shab-related
subfamily, member 2 [Homo sapiens]
Length = 911
Score = 280 bits (716), Expect = 2e-75
Identities = 179/460 (38%), Positives = 252/460 (54%), Gaps = 61/460 (13%)
Query: 73 PPGPEPVVLNEG-NQRVIINIAGLRFETQLRTLSQFPETLLGD------REKRMQFFDSM 125
PP P ++ ++ ++RV IN+ GL E RTL + P T LG E ++ D
Sbjct: 21 PPEPVDIIRSKTCSRRVKINVGGLNHEVLWRTLDRLPRTRLGKLRDCNTHESLLEVCDDY 80
Query: 126 R---NEYFFDRNRPSFDGILYYYQSGGKIRRPANVPIDIFADEISFY------------- 169
NEYFFDR+ +F IL +Y++G K+ + F E+ ++
Sbjct: 81 NLNENEYFFDRHPGAFTSILNFYRTG-KLHMMEEMCALSFGQELDYWGIDEIYLESCCQA 139
Query: 170 -----------ELGSEAMDQFREDEGFIKDPETLLPTNDIHRQFWLLFEYPESSSAARAV 218
EL EA + RE EG D T P D ++ W L E P SS AA+ +
Sbjct: 140 RYHQKKEQMNEELRREA-ETMREREGEEFD-NTCCP--DKRKKLWDLLEKPNSSVAAKIL 195
Query: 219 AVVSVLVVVISITIFCLETLPEFREDRELKVVRDPNLNMSKTVLSQTMFTDPFFMVESTC 278
A+VS+L +V+S L TLPE +E E + D N ++ VE+ C
Sbjct: 196 AIVSILFIVLSTIALSLNTLPELQETDEFGQLND-NRQLAH--------------VEAVC 240
Query: 279 IVWFTFELVLRFVVCPSKTDFFRNIMNIIDIISIIPYFATLITELVQETEPSAQQNMSLA 338
I WFT E +LRF+ P+K FF+ +N+ID+++I+PY+ T+ L + + Q
Sbjct: 241 IAWFTMEYLLRFLSSPNKWKFFKGPLNVIDLLAILPYYVTIF--LTESNKSVLQFQNVRR 298
Query: 339 ILRIIRLVRVFRIFKLSRHSKGLQILGQTLKASMRELGLLIFFLFIGVILFSSAVYFAEV 398
+++I R++R+ RI KL+RHS GLQ LG TL+ S ELGLLI FL +G+++FSS V+FAE
Sbjct: 299 VVQIFRIMRILRILKLARHSTGLQSLGFTLRRSYNELGLLILFLAMGIMIFSSLVFFAEK 358
Query: 399 DEPESHFSSIPDGFWWAVVTMTTVGYGDMCPTTPGGKIVGTLCAIAGVLTIALPVPVIVS 458
DE + F+SIP FWWA +TMTTVGYGD+ P T GKIVG LC IAGVL IALP+P+IV+
Sbjct: 359 DEDATKFTSIPASFWWATITMTTVGYGDIYPKTLLGKIVGGLCCIAGVLVIALPIPIIVN 418
Query: 459 NFNYFYHRETENEEKQNIPGEIERILNSVGSRMGSTDSLN 498
NF+ FY + E+ +ER R GS S+N
Sbjct: 419 NFSEFYKEQKRQEKAIKRREALER-----AKRNGSIVSMN 453
>gi|4826784 potassium voltage-gated channel, Shab-related subfamily,
member 1 [Homo sapiens]
Length = 858
Score = 270 bits (691), Expect = 2e-72
Identities = 169/456 (37%), Positives = 248/456 (54%), Gaps = 53/456 (11%)
Query: 73 PPGPEPVVLNEG-NQRVIINIAGLRFETQLRTLSQFPETLLGD------REKRMQFFDSM 125
PP P +V ++ ++RV +N+ GL E RTL + P T LG + ++ D
Sbjct: 17 PPEPMEIVRSKACSRRVRLNVGGLAHEVLWRTLDRLPRTRLGKLRDCNTHDSLLEVCDDY 76
Query: 126 R---NEYFFDRNRPSFDGILYYYQSGGKIRRPANVPIDIFADEISFY---ELGSEAMDQF 179
NEYFFDR+ +F IL +Y++G ++ + F+ E+ ++ E+ E+ Q
Sbjct: 77 SLDDNEYFFDRHPGAFTSILNFYRTG-RLHMMEEMCALSFSQELDYWGIDEIYLESCCQA 135
Query: 180 RE-------DEGFIKDPETLLPTN----------DIHRQFWLLFEYPESSSAARAVAVVS 222
R +E ++ ETL + ++ W L E P SS AA+ +A++S
Sbjct: 136 RYHQKKEQMNEELKREAETLREREGEEFDNTCCAEKRKKLWDLLEKPNSSVAAKILAIIS 195
Query: 223 VLVVVISITIFCLETLPEFREDRELKVVRDPNLNMSKTVLSQTMFTDPFFMVESTCIVWF 282
++ +V+S L TLPE + E Q+ VE+ CI WF
Sbjct: 196 IMFIVLSTIALSLNTLPELQSLDEF---------------GQSTDNPQLAHVEAVCIAWF 240
Query: 283 TFELVLRFVVCPSKTDFFRNIMNIIDIISIIPYFATLITELVQETEPSAQQNMSLAILRI 342
T E +LRF+ P K FF+ +N ID+++I+PY+ T+ L + + Q +++I
Sbjct: 241 TMEYLLRFLSSPKKWKFFKGPLNAIDLLAILPYYVTIF--LTESNKSVLQFQNVRRVVQI 298
Query: 343 IRLVRVFRIFKLSRHSKGLQILGQTLKASMRELGLLIFFLFIGVILFSSAVYFAEVDEPE 402
R++R+ RI KL+RHS GLQ LG TL+ S ELGLLI FL +G+++FSS V+FAE DE +
Sbjct: 299 FRIMRILRILKLARHSTGLQSLGFTLRRSYNELGLLILFLAMGIMIFSSLVFFAEKDEDD 358
Query: 403 SHFSSIPDGFWWAVVTMTTVGYGDMCPTTPGGKIVGTLCAIAGVLTIALPVPVIVSNFNY 462
+ F SIP FWWA +TMTTVGYGD+ P T GKIVG LC IAGVL IALP+P+IV+NF+
Sbjct: 359 TKFKSIPASFWWATITMTTVGYGDIYPKTLLGKIVGGLCCIAGVLVIALPIPIIVNNFSE 418
Query: 463 FYHRETENEEKQNIPGEIERILNSVGSRMGSTDSLN 498
FY + E+ +ER R GS S+N
Sbjct: 419 FYKEQKRQEKAIKRREALER-----AKRNGSIVSMN 449
>gi|27436981 potassium voltage-gated channel, Shal-related
subfamily, member 1 [Homo sapiens]
Length = 647
Score = 269 bits (687), Expect = 5e-72
Identities = 162/451 (35%), Positives = 260/451 (57%), Gaps = 44/451 (9%)
Query: 73 PPGPEPVVLNEGNQRVIINIAGLRFETQLRTLSQFPETLLGDREKRMQFFDSMRNEYFFD 132
PP P V + G++ +++N++G RFET TL ++P+TLLG EK F+D+ EYFFD
Sbjct: 28 PPAPG-VKASRGDEVLVVNVSGRRFETWKNTLDRYPDTLLGSSEKEF-FYDADSGEYFFD 85
Query: 133 RNRPSFDGILYYYQSGGKIRRPANVPIDIFADEISFYEL-----GSEAMDQFRED----- 182
R+ F +L +Y++G ++ P I F +E++FY L G ++++R+
Sbjct: 86 RDPDMFRHVLNFYRTG-RLHCPRQECIQAFDEELAFYGLVPELVGDCCLEEYRDRKKENA 144
Query: 183 EGFIKDPET-------LLPTNDIHRQ-FWLLFEYPESSSAARAVAVVSVLVVVISITIFC 234
E +D E LP RQ W FE P +S+AA V+ + +S+
Sbjct: 145 ERLAEDEEAEQAGDGPALPAGSSLRQRLWRAFENPHTSTAALVFYYVTGFFIAVSVIANV 204
Query: 235 LETLPEFREDRELKVVRDPNLNMSKTVLSQTMFTDPFFMVESTCIVWFTFELVLRFVVCP 294
+ET+P R S+ F FF +++ C++ FT E +LR P
Sbjct: 205 VETIP----------CRGSARRSSREQPCGERFPQAFFCMDTACVLIFTGEYLLRLFAAP 254
Query: 295 SKTDFFRNIMNIIDIISIIPYFATLITELVQETEPSAQQNMSLAILRIIRLVRVFRIFKL 354
S+ F R++M++ID+++I+PY+ L+ ++S A + + R+ RVFRIFK
Sbjct: 255 SRCRFLRSVMSLIDVVAILPYYIGLLVP--------KNDDVSGAFVTL-RVFRVFRIFKF 305
Query: 355 SRHSKGLQILGQTLKASMRELGLLIFFLFIGVILFSSAVYFAEVDEPESHFSSIPDGFWW 414
SRHS+GL+ILG TLK+ ELG L+F L + +I+F++ +++AE +++F+SIP FW+
Sbjct: 306 SRHSQGLRILGYTLKSCASELGFLLFSLTMAIIIFATVMFYAEKGTNKTNFTSIPAAFWY 365
Query: 415 AVVTMTTVGYGDMCPTTPGGKIVGTLCAIAGVLTIALPVPVIVSNFNYFYHRETENEEKQ 474
+VTMTT+GYGDM P+T GKI G++C+++GVL IALPVPVIVSNF+ YH + + +K+
Sbjct: 366 TIVTMTTLGYGDMVPSTIAGKIFGSICSLSGVLVIALPVPVIVSNFSRIYH-QNQRADKR 424
Query: 475 NIPGEIERILNSVGSRMGSTDSL--NKTNGG 503
++ R+ ++ G+T++ K NGG
Sbjct: 425 RAQQKV-RLARIRLAKSGTTNAFLQYKQNGG 454
>gi|4826786 Shaw-related voltage-gated potassium channel protein 1
isoform B [Homo sapiens]
Length = 511
Score = 263 bits (671), Expect = 4e-70
Identities = 169/464 (36%), Positives = 251/464 (54%), Gaps = 80/464 (17%)
Query: 85 NQRVIINIAGLRFETQLRTLSQFPETLLG---DREKRMQF-FDSMRNEYFFDRNRPSFDG 140
++R++IN+ G R +T TL P T L + + F +D +E+FFDR+ F
Sbjct: 7 SERIVINVGGTRHQTYRSTLRTLPGTRLAWLAEPDAHSHFDYDPRADEFFFDRHPGVFAH 66
Query: 141 ILYYYQSGGKIRRPANVPIDIFADEISFYEL------------------GSEAMDQFR-- 180
IL YY++G K+ PA+V ++ +E++F+ + EA+D F
Sbjct: 67 ILNYYRTG-KLHCPADVCGPLYEEELAFWGIDETDVEPCCWMTYRQHRDAEEALDSFGGA 125
Query: 181 --------------------EDEGFIKDPETLLPTND---------IHRQFWLLFEYPES 211
EDE + L + D + W LFE P S
Sbjct: 126 PLDNSADDADADGPGDSGDGEDELEMTKRLALSDSPDGRPGGFWRRWQPRIWALFEDPYS 185
Query: 212 SSAARAVAVVSVLVVVISITIFCLETLPEFR---EDRELKVVRDPNLNMSKTVLSQTMFT 268
S AR VA S+ +++SIT FCLET F E++ VR N ++ + T
Sbjct: 186 SRYARYVAFASLFFILVSITTFCLETHERFNPIVNKTEIENVR----NGTQVRYYREAET 241
Query: 269 DPFFM-VESTCIVWFTFELVLRFVVCPSKTDFFRNIMNIIDIISIIPYFATLITELVQET 327
+ F +E C+VWFTFE ++R + CP+K +F +N +NIID ++I+P++ E+
Sbjct: 242 EAFLTYIEGVCVVWFTFEFLMRVIFCPNKVEFIKNSLNIIDFVAILPFYL----EVGLSG 297
Query: 328 EPSAQQNMSLAILRIIRLVRVFRIFKLSRHSKGLQILGQTLKASMRELGLLIFFLFIGVI 387
S L LR++R VR+ RIFKL+RH GL++LG TL+AS E LLI FL +GV+
Sbjct: 298 LSSKAAKDVLGFLRVVRFVRILRIFKLTRHFVGLRVLGHTLRASTNEFLLLIIFLALGVL 357
Query: 388 LFSSAVYFAE-----VDEPES----HFSSIPDGFWWAVVTMTTVGYGDMCPTTPGGKIVG 438
+F++ +Y+AE ++P + HF +IP GFWWAVVTMTT+GYGDM P T G +VG
Sbjct: 358 IFATMIYYAERIGAQPNDPSASEHTHFKNIPIGFWWAVVTMTTLGYGDMYPQTWSGMLVG 417
Query: 439 TLCAIAGVLTIALPVPVIVSNFNYFY-----HRETENEEKQNIP 477
LCA+AGVLTIA+PVPVIV+NF +Y ++ ++K++IP
Sbjct: 418 ALCALAGVLTIAMPVPVIVNNFGMYYSLAMAKQKLPKKKKKHIP 461
>gi|163792201 Shaw-related voltage-gated potassium channel protein 1
isoform A [Homo sapiens]
Length = 585
Score = 263 bits (671), Expect = 4e-70
Identities = 169/464 (36%), Positives = 251/464 (54%), Gaps = 80/464 (17%)
Query: 85 NQRVIINIAGLRFETQLRTLSQFPETLLG---DREKRMQF-FDSMRNEYFFDRNRPSFDG 140
++R++IN+ G R +T TL P T L + + F +D +E+FFDR+ F
Sbjct: 7 SERIVINVGGTRHQTYRSTLRTLPGTRLAWLAEPDAHSHFDYDPRADEFFFDRHPGVFAH 66
Query: 141 ILYYYQSGGKIRRPANVPIDIFADEISFYEL------------------GSEAMDQFR-- 180
IL YY++G K+ PA+V ++ +E++F+ + EA+D F
Sbjct: 67 ILNYYRTG-KLHCPADVCGPLYEEELAFWGIDETDVEPCCWMTYRQHRDAEEALDSFGGA 125
Query: 181 --------------------EDEGFIKDPETLLPTND---------IHRQFWLLFEYPES 211
EDE + L + D + W LFE P S
Sbjct: 126 PLDNSADDADADGPGDSGDGEDELEMTKRLALSDSPDGRPGGFWRRWQPRIWALFEDPYS 185
Query: 212 SSAARAVAVVSVLVVVISITIFCLETLPEFR---EDRELKVVRDPNLNMSKTVLSQTMFT 268
S AR VA S+ +++SIT FCLET F E++ VR N ++ + T
Sbjct: 186 SRYARYVAFASLFFILVSITTFCLETHERFNPIVNKTEIENVR----NGTQVRYYREAET 241
Query: 269 DPFFM-VESTCIVWFTFELVLRFVVCPSKTDFFRNIMNIIDIISIIPYFATLITELVQET 327
+ F +E C+VWFTFE ++R + CP+K +F +N +NIID ++I+P++ E+
Sbjct: 242 EAFLTYIEGVCVVWFTFEFLMRVIFCPNKVEFIKNSLNIIDFVAILPFYL----EVGLSG 297
Query: 328 EPSAQQNMSLAILRIIRLVRVFRIFKLSRHSKGLQILGQTLKASMRELGLLIFFLFIGVI 387
S L LR++R VR+ RIFKL+RH GL++LG TL+AS E LLI FL +GV+
Sbjct: 298 LSSKAAKDVLGFLRVVRFVRILRIFKLTRHFVGLRVLGHTLRASTNEFLLLIIFLALGVL 357
Query: 388 LFSSAVYFAE-----VDEPES----HFSSIPDGFWWAVVTMTTVGYGDMCPTTPGGKIVG 438
+F++ +Y+AE ++P + HF +IP GFWWAVVTMTT+GYGDM P T G +VG
Sbjct: 358 IFATMIYYAERIGAQPNDPSASEHTHFKNIPIGFWWAVVTMTTLGYGDMYPQTWSGMLVG 417
Query: 439 TLCAIAGVLTIALPVPVIVSNFNYFY-----HRETENEEKQNIP 477
LCA+AGVLTIA+PVPVIV+NF +Y ++ ++K++IP
Sbjct: 418 ALCALAGVLTIAMPVPVIVNNFGMYYSLAMAKQKLPKKKKKHIP 461
>gi|88758576 Shaw-related voltage-gated potassium channel protein 4
isoform c [Homo sapiens]
Length = 626
Score = 260 bits (665), Expect = 2e-69
Identities = 170/477 (35%), Positives = 247/477 (51%), Gaps = 82/477 (17%)
Query: 77 EPVVLNEGNQRVIINIAGLRFETQLRTLSQFPETLL---------GDREKRMQFFDSMRN 127
E + E ++++IIN+ G R ET TL P T L G E S +
Sbjct: 27 EEMAKGEASEKIIINVGGTRHETYRSTLRTLPGTRLAWLADPDGGGRPETDGGGVGSSGS 86
Query: 128 ------EYFFDRNRPSFDGILYYYQSGGKIRRPANVPIDIFADEISFYEL---------- 171
E+FFDR+ F +L YY++G K+ PA+V +F +E++F+ +
Sbjct: 87 SGGGGCEFFFDRHPGVFAYVLNYYRTG-KLHCPADVCGPLFEEELTFWGIDETDVEPCCW 145
Query: 172 --------GSEAMDQFRE-----------DEGFIKDPETLLPTNDIHR------------ 200
EA+D F DE + E L H
Sbjct: 146 MTYRQHRDAEEALDIFESPDGGGSGAGPSDEAGDDERELALQRLGPHEGGAGHGAGSGGC 205
Query: 201 -----QFWLLFEYPESSSAARAVAVVSVLVVVISITIFCLETLPEFREDRELKVVRDPNL 255
+ W LFE P SS AAR VA S+ +++SIT FCLET F DR + +
Sbjct: 206 RGWQPRMWALFEDPYSSRAARVVAFASLFFILVSITTFCLETHEAFNIDRNVTEILRVG- 264
Query: 256 NMSKTVLSQTMFTDPFFM-VESTCIVWFTFELVLRFVVCPSKTDFFRNIMNIIDIISIIP 314
N++ + + T+P +E C++WFT E ++R V CP DF +N++NIID ++I+P
Sbjct: 265 NITSVHFRREVETEPILTYIEGVCVLWFTLEFLVRIVCCPDTLDFVKNLLNIIDFVAILP 324
Query: 315 YFATLITELVQETEPSAQQNMSLAILRIIRLVRVFRIFKLSRHSKGLQILGQTLKASMRE 374
++ E+ S L LR++R VR+ RIFKL+RH GL++LG TL+AS E
Sbjct: 325 FYL----EVGLSGLSSKAARDVLGFLRVVRFVRILRIFKLTRHFVGLRVLGHTLRASTNE 380
Query: 375 LGLLIFFLFIGVILFSSAVYFAE-----VDEPESH----FSSIPDGFWWAVVTMTTVGYG 425
LLI FL +GV++F++ +Y+AE +P + F +IP GFWWAVVTMTT+GYG
Sbjct: 381 FLLLIIFLALGVLIFATMIYYAERIGARPSDPRGNDHTDFKNIPIGFWWAVVTMTTLGYG 440
Query: 426 DMCPTTPGGKIVGTLCAIAGVLTIALPVPVIVSNFNYFY-----HRETENEEKQNIP 477
DM P T G +VG LCA+AGVLTIA+PVPVIV+NF +Y ++ + K+++P
Sbjct: 441 DMYPKTWSGMLVGALCALAGVLTIAMPVPVIVNNFGMYYSLAMAKQKLPKKRKKHVP 497
>gi|24497462 Shaw-related voltage-gated potassium channel protein 4
isoform a [Homo sapiens]
Length = 635
Score = 260 bits (665), Expect = 2e-69
Identities = 170/477 (35%), Positives = 247/477 (51%), Gaps = 82/477 (17%)
Query: 77 EPVVLNEGNQRVIINIAGLRFETQLRTLSQFPETLL---------GDREKRMQFFDSMRN 127
E + E ++++IIN+ G R ET TL P T L G E S +
Sbjct: 27 EEMAKGEASEKIIINVGGTRHETYRSTLRTLPGTRLAWLADPDGGGRPETDGGGVGSSGS 86
Query: 128 ------EYFFDRNRPSFDGILYYYQSGGKIRRPANVPIDIFADEISFYEL---------- 171
E+FFDR+ F +L YY++G K+ PA+V +F +E++F+ +
Sbjct: 87 SGGGGCEFFFDRHPGVFAYVLNYYRTG-KLHCPADVCGPLFEEELTFWGIDETDVEPCCW 145
Query: 172 --------GSEAMDQFRE-----------DEGFIKDPETLLPTNDIHR------------ 200
EA+D F DE + E L H
Sbjct: 146 MTYRQHRDAEEALDIFESPDGGGSGAGPSDEAGDDERELALQRLGPHEGGAGHGAGSGGC 205
Query: 201 -----QFWLLFEYPESSSAARAVAVVSVLVVVISITIFCLETLPEFREDRELKVVRDPNL 255
+ W LFE P SS AAR VA S+ +++SIT FCLET F DR + +
Sbjct: 206 RGWQPRMWALFEDPYSSRAARVVAFASLFFILVSITTFCLETHEAFNIDRNVTEILRVG- 264
Query: 256 NMSKTVLSQTMFTDPFFM-VESTCIVWFTFELVLRFVVCPSKTDFFRNIMNIIDIISIIP 314
N++ + + T+P +E C++WFT E ++R V CP DF +N++NIID ++I+P
Sbjct: 265 NITSVHFRREVETEPILTYIEGVCVLWFTLEFLVRIVCCPDTLDFVKNLLNIIDFVAILP 324
Query: 315 YFATLITELVQETEPSAQQNMSLAILRIIRLVRVFRIFKLSRHSKGLQILGQTLKASMRE 374
++ E+ S L LR++R VR+ RIFKL+RH GL++LG TL+AS E
Sbjct: 325 FYL----EVGLSGLSSKAARDVLGFLRVVRFVRILRIFKLTRHFVGLRVLGHTLRASTNE 380
Query: 375 LGLLIFFLFIGVILFSSAVYFAE-----VDEPESH----FSSIPDGFWWAVVTMTTVGYG 425
LLI FL +GV++F++ +Y+AE +P + F +IP GFWWAVVTMTT+GYG
Sbjct: 381 FLLLIIFLALGVLIFATMIYYAERIGARPSDPRGNDHTDFKNIPIGFWWAVVTMTTLGYG 440
Query: 426 DMCPTTPGGKIVGTLCAIAGVLTIALPVPVIVSNFNYFY-----HRETENEEKQNIP 477
DM P T G +VG LCA+AGVLTIA+PVPVIV+NF +Y ++ + K+++P
Sbjct: 441 DMYPKTWSGMLVGALCALAGVLTIAMPVPVIVNNFGMYYSLAMAKQKLPKKRKKHVP 497
>gi|24497464 Shaw-related voltage-gated potassium channel protein 4
isoform b [Homo sapiens]
Length = 582
Score = 260 bits (665), Expect = 2e-69
Identities = 170/477 (35%), Positives = 247/477 (51%), Gaps = 82/477 (17%)
Query: 77 EPVVLNEGNQRVIINIAGLRFETQLRTLSQFPETLL---------GDREKRMQFFDSMRN 127
E + E ++++IIN+ G R ET TL P T L G E S +
Sbjct: 27 EEMAKGEASEKIIINVGGTRHETYRSTLRTLPGTRLAWLADPDGGGRPETDGGGVGSSGS 86
Query: 128 ------EYFFDRNRPSFDGILYYYQSGGKIRRPANVPIDIFADEISFYEL---------- 171
E+FFDR+ F +L YY++G K+ PA+V +F +E++F+ +
Sbjct: 87 SGGGGCEFFFDRHPGVFAYVLNYYRTG-KLHCPADVCGPLFEEELTFWGIDETDVEPCCW 145
Query: 172 --------GSEAMDQFRE-----------DEGFIKDPETLLPTNDIHR------------ 200
EA+D F DE + E L H
Sbjct: 146 MTYRQHRDAEEALDIFESPDGGGSGAGPSDEAGDDERELALQRLGPHEGGAGHGAGSGGC 205
Query: 201 -----QFWLLFEYPESSSAARAVAVVSVLVVVISITIFCLETLPEFREDRELKVVRDPNL 255
+ W LFE P SS AAR VA S+ +++SIT FCLET F DR + +
Sbjct: 206 RGWQPRMWALFEDPYSSRAARVVAFASLFFILVSITTFCLETHEAFNIDRNVTEILRVG- 264
Query: 256 NMSKTVLSQTMFTDPFFM-VESTCIVWFTFELVLRFVVCPSKTDFFRNIMNIIDIISIIP 314
N++ + + T+P +E C++WFT E ++R V CP DF +N++NIID ++I+P
Sbjct: 265 NITSVHFRREVETEPILTYIEGVCVLWFTLEFLVRIVCCPDTLDFVKNLLNIIDFVAILP 324
Query: 315 YFATLITELVQETEPSAQQNMSLAILRIIRLVRVFRIFKLSRHSKGLQILGQTLKASMRE 374
++ E+ S L LR++R VR+ RIFKL+RH GL++LG TL+AS E
Sbjct: 325 FYL----EVGLSGLSSKAARDVLGFLRVVRFVRILRIFKLTRHFVGLRVLGHTLRASTNE 380
Query: 375 LGLLIFFLFIGVILFSSAVYFAE-----VDEPESH----FSSIPDGFWWAVVTMTTVGYG 425
LLI FL +GV++F++ +Y+AE +P + F +IP GFWWAVVTMTT+GYG
Sbjct: 381 FLLLIIFLALGVLIFATMIYYAERIGARPSDPRGNDHTDFKNIPIGFWWAVVTMTTLGYG 440
Query: 426 DMCPTTPGGKIVGTLCAIAGVLTIALPVPVIVSNFNYFY-----HRETENEEKQNIP 477
DM P T G +VG LCA+AGVLTIA+PVPVIV+NF +Y ++ + K+++P
Sbjct: 441 DMYPKTWSGMLVGALCALAGVLTIAMPVPVIVNNFGMYYSLAMAKQKLPKKRKKHVP 497
>gi|27436984 potassium voltage-gated channel, Shal-related
subfamily, member 3 isoform 1 [Homo sapiens]
Length = 655
Score = 259 bits (663), Expect = 3e-69
Identities = 149/418 (35%), Positives = 243/418 (58%), Gaps = 42/418 (10%)
Query: 76 PEPVVLNEGNQR----VIINIAGLRFETQLRTLSQFPETLLGDREKRMQFFDSMRNEYFF 131
P P+ + N+R +++N++G RF+T TL ++P+TLLG EK FF+ EYFF
Sbjct: 26 PMPLAPADKNKRQDELIVLNVSGRRFQTWRTTLERYPDTLLGSTEKEF-FFNEDTKEYFF 84
Query: 132 DRNRPSFDGILYYYQSGGKIRRPANVPIDIFADEISFYELGSEAM---------DQFRE- 181
DR+ F +L +Y++G K+ P I + DE++FY + E + D+ RE
Sbjct: 85 DRDPEVFRCVLNFYRTG-KLHYPRYECISAYDDELAFYGILPEIIGDCCYEEYKDRKREN 143
Query: 182 -----DEGFIKDPETLLPTNDIHRQFWLLFEYPESSSAARAVAVVSVLVVVISITIFCLE 236
D+ ++ + +P+ + W FE P +S+ A V+ + +S+ +E
Sbjct: 144 AERLMDDNDSENNQESMPSLSFRQTMWRAFENPHTSTLALVFYYVTGFFIAVSVITNVVE 203
Query: 237 TLPEFREDRELKVVRDPNLNMSKTVLSQTMFTDPFFMVESTCIVWFTFELVLRFVVCPSK 296
T+P + SK + ++ FF +++ C++ FT E +LR PS+
Sbjct: 204 TVP------------CGTVPGSKELPCGERYSVAFFCLDTACVMIFTVEYLLRLFAAPSR 251
Query: 297 TDFFRNIMNIIDIISIIPYFATLITELVQETEPSAQQNMSLAILRIIRLVRVFRIFKLSR 356
F R++M+IID+++I+PY+ L+ + +++S A + + R+ RVFRIFK SR
Sbjct: 252 YRFIRSVMSIIDVVAIMPYYIGLVM--------TNNEDVSGAFVTL-RVFRVFRIFKFSR 302
Query: 357 HSKGLQILGQTLKASMRELGLLIFFLFIGVILFSSAVYFAEVDEPESHFSSIPDGFWWAV 416
HS+GL+ILG TLK+ ELG L+F L + +I+F++ +++AE S F+SIP FW+ +
Sbjct: 303 HSQGLRILGYTLKSCASELGFLLFSLTMAIIIFATVMFYAEKGSSASKFTSIPASFWYTI 362
Query: 417 VTMTTVGYGDMCPTTPGGKIVGTLCAIAGVLTIALPVPVIVSNFNYFYHRETENEEKQ 474
VTMTT+GYGDM P T GKI G++C+++GVL IALPVPVIVSNF+ YH+ ++++
Sbjct: 363 VTMTTLGYGDMVPKTIAGKIFGSICSLSGVLVIALPVPVIVSNFSRIYHQNQRADKRR 420
>gi|27436986 potassium voltage-gated channel, Shal-related
subfamily, member 3 isoform 2 [Homo sapiens]
Length = 636
Score = 259 bits (663), Expect = 3e-69
Identities = 149/418 (35%), Positives = 243/418 (58%), Gaps = 42/418 (10%)
Query: 76 PEPVVLNEGNQR----VIINIAGLRFETQLRTLSQFPETLLGDREKRMQFFDSMRNEYFF 131
P P+ + N+R +++N++G RF+T TL ++P+TLLG EK FF+ EYFF
Sbjct: 26 PMPLAPADKNKRQDELIVLNVSGRRFQTWRTTLERYPDTLLGSTEKEF-FFNEDTKEYFF 84
Query: 132 DRNRPSFDGILYYYQSGGKIRRPANVPIDIFADEISFYELGSEAM---------DQFRE- 181
DR+ F +L +Y++G K+ P I + DE++FY + E + D+ RE
Sbjct: 85 DRDPEVFRCVLNFYRTG-KLHYPRYECISAYDDELAFYGILPEIIGDCCYEEYKDRKREN 143
Query: 182 -----DEGFIKDPETLLPTNDIHRQFWLLFEYPESSSAARAVAVVSVLVVVISITIFCLE 236
D+ ++ + +P+ + W FE P +S+ A V+ + +S+ +E
Sbjct: 144 AERLMDDNDSENNQESMPSLSFRQTMWRAFENPHTSTLALVFYYVTGFFIAVSVITNVVE 203
Query: 237 TLPEFREDRELKVVRDPNLNMSKTVLSQTMFTDPFFMVESTCIVWFTFELVLRFVVCPSK 296
T+P + SK + ++ FF +++ C++ FT E +LR PS+
Sbjct: 204 TVP------------CGTVPGSKELPCGERYSVAFFCLDTACVMIFTVEYLLRLFAAPSR 251
Query: 297 TDFFRNIMNIIDIISIIPYFATLITELVQETEPSAQQNMSLAILRIIRLVRVFRIFKLSR 356
F R++M+IID+++I+PY+ L+ + +++S A + + R+ RVFRIFK SR
Sbjct: 252 YRFIRSVMSIIDVVAIMPYYIGLVM--------TNNEDVSGAFVTL-RVFRVFRIFKFSR 302
Query: 357 HSKGLQILGQTLKASMRELGLLIFFLFIGVILFSSAVYFAEVDEPESHFSSIPDGFWWAV 416
HS+GL+ILG TLK+ ELG L+F L + +I+F++ +++AE S F+SIP FW+ +
Sbjct: 303 HSQGLRILGYTLKSCASELGFLLFSLTMAIIIFATVMFYAEKGSSASKFTSIPASFWYTI 362
Query: 417 VTMTTVGYGDMCPTTPGGKIVGTLCAIAGVLTIALPVPVIVSNFNYFYHRETENEEKQ 474
VTMTT+GYGDM P T GKI G++C+++GVL IALPVPVIVSNF+ YH+ ++++
Sbjct: 363 VTMTTLGYGDMVPKTIAGKIFGSICSLSGVLVIALPVPVIVSNFSRIYHQNQRADKRR 420
>gi|21217561 Shaw-related voltage-gated potassium channel protein 2
isoform KV3.2a [Homo sapiens]
Length = 613
Score = 257 bits (656), Expect = 2e-68
Identities = 163/433 (37%), Positives = 237/433 (54%), Gaps = 62/433 (14%)
Query: 128 EYFFDRNRPSFDGILYYYQSGGKIRRPANVPIDIFADEISFYEL---------------- 171
E+FFDR+ F +L YY++G K+ PA+V +F +E++F+ +
Sbjct: 101 EFFFDRHPGVFAYVLNYYRTG-KLHCPADVCGPLFEEELAFWGIDETDVEPCCWMTYRQH 159
Query: 172 --GSEAMDQFREDEGFIKDP---ETL----LPTND----------------IHRQFWLLF 206
EA+D F + DP E L L D + + W LF
Sbjct: 160 RDAEEALDIFETPDLIGGDPGDDEDLAAKRLGIEDAAGLGGPDGKSGRWRRLQPRMWALF 219
Query: 207 EYPESSSAARAVAVVSVLVVVISITIFCLETLPEFREDRELKVVRDPNLNMSKTVLSQTM 266
E P SS AAR +A S+ +++SIT FCLET F +K +P +N + VL +
Sbjct: 220 EDPYSSRAARFIAFASLFFILVSITTFCLETHEAFNI---VKNKTEPVINGTSVVLQYEI 276
Query: 267 FTDPFFM-VESTCIVWFTFELVLRFVVCPSKTDFFRNIMNIIDIISIIPYFATLITELVQ 325
TDP VE C+VWFTFE ++R V P+K +F +N++NIID ++I+P++ E+
Sbjct: 277 ETDPALTYVEGVCVVWFTFEFLVRIVFSPNKLEFIKNLLNIIDFVAILPFYL----EVGL 332
Query: 326 ETEPSAQQNMSLAILRIIRLVRVFRIFKLSRHSKGLQILGQTLKASMRELGLLIFFLFIG 385
S L LR++R VR+ RIFKL+RH GL++LG TL+AS E LLI FL +G
Sbjct: 333 SGLSSKAAKDVLGFLRVVRFVRILRIFKLTRHFVGLRVLGHTLRASTNEFLLLIIFLALG 392
Query: 386 VILFSSAVYFAE-----VDEPES----HFSSIPDGFWWAVVTMTTVGYGDMCPTTPGGKI 436
V++F++ +Y+AE ++P + F +IP GFWWAVVTMTT+GYGDM P T G +
Sbjct: 393 VLIFATMIYYAERVGAQPNDPSASEHTQFKNIPIGFWWAVVTMTTLGYGDMYPQTWSGML 452
Query: 437 VGTLCAIAGVLTIALPVPVIVSNFNYFYHRETENEEKQNIPGEIERILNSVGSRMGSTDS 496
VG LCA+AGVLTIA+PVPVIV+NF +Y KQ +P + ++ + T
Sbjct: 453 VGALCALAGVLTIAMPVPVIVNNFGMYYSLAM---AKQKLPRKRKKHIPPAPQASSPTFC 509
Query: 497 LNKTNGGCSTEKS 509
+ N C++ +S
Sbjct: 510 KTELNMACNSTQS 522
Score = 32.3 bits (72), Expect = 1.1
Identities = 15/30 (50%), Positives = 18/30 (60%)
Query: 83 EGNQRVIINIAGLRFETQLRTLSQFPETLL 112
E N+RVI+N+ G R ET TL P T L
Sbjct: 5 ENNERVILNVGGTRHETYRSTLKTLPGTRL 34
>gi|21217563 Shaw-related voltage-gated potassium channel protein 2
isoform KV3.2b [Homo sapiens]
Length = 638
Score = 257 bits (656), Expect = 2e-68
Identities = 163/433 (37%), Positives = 237/433 (54%), Gaps = 62/433 (14%)
Query: 128 EYFFDRNRPSFDGILYYYQSGGKIRRPANVPIDIFADEISFYEL---------------- 171
E+FFDR+ F +L YY++G K+ PA+V +F +E++F+ +
Sbjct: 101 EFFFDRHPGVFAYVLNYYRTG-KLHCPADVCGPLFEEELAFWGIDETDVEPCCWMTYRQH 159
Query: 172 --GSEAMDQFREDEGFIKDP---ETL----LPTND----------------IHRQFWLLF 206
EA+D F + DP E L L D + + W LF
Sbjct: 160 RDAEEALDIFETPDLIGGDPGDDEDLAAKRLGIEDAAGLGGPDGKSGRWRRLQPRMWALF 219
Query: 207 EYPESSSAARAVAVVSVLVVVISITIFCLETLPEFREDRELKVVRDPNLNMSKTVLSQTM 266
E P SS AAR +A S+ +++SIT FCLET F +K +P +N + VL +
Sbjct: 220 EDPYSSRAARFIAFASLFFILVSITTFCLETHEAFNI---VKNKTEPVINGTSVVLQYEI 276
Query: 267 FTDPFFM-VESTCIVWFTFELVLRFVVCPSKTDFFRNIMNIIDIISIIPYFATLITELVQ 325
TDP VE C+VWFTFE ++R V P+K +F +N++NIID ++I+P++ E+
Sbjct: 277 ETDPALTYVEGVCVVWFTFEFLVRIVFSPNKLEFIKNLLNIIDFVAILPFYL----EVGL 332
Query: 326 ETEPSAQQNMSLAILRIIRLVRVFRIFKLSRHSKGLQILGQTLKASMRELGLLIFFLFIG 385
S L LR++R VR+ RIFKL+RH GL++LG TL+AS E LLI FL +G
Sbjct: 333 SGLSSKAAKDVLGFLRVVRFVRILRIFKLTRHFVGLRVLGHTLRASTNEFLLLIIFLALG 392
Query: 386 VILFSSAVYFAE-----VDEPES----HFSSIPDGFWWAVVTMTTVGYGDMCPTTPGGKI 436
V++F++ +Y+AE ++P + F +IP GFWWAVVTMTT+GYGDM P T G +
Sbjct: 393 VLIFATMIYYAERVGAQPNDPSASEHTQFKNIPIGFWWAVVTMTTLGYGDMYPQTWSGML 452
Query: 437 VGTLCAIAGVLTIALPVPVIVSNFNYFYHRETENEEKQNIPGEIERILNSVGSRMGSTDS 496
VG LCA+AGVLTIA+PVPVIV+NF +Y KQ +P + ++ + T
Sbjct: 453 VGALCALAGVLTIAMPVPVIVNNFGMYYSLAM---AKQKLPRKRKKHIPPAPQASSPTFC 509
Query: 497 LNKTNGGCSTEKS 509
+ N C++ +S
Sbjct: 510 KTELNMACNSTQS 522
Score = 32.3 bits (72), Expect = 1.1
Identities = 15/30 (50%), Positives = 18/30 (60%)
Query: 83 EGNQRVIINIAGLRFETQLRTLSQFPETLL 112
E N+RVI+N+ G R ET TL P T L
Sbjct: 5 ENNERVILNVGGTRHETYRSTLKTLPGTRL 34
>gi|24497458 Shaw-related voltage-gated potassium channel protein 2
isoform KV3.2c [Homo sapiens]
Length = 558
Score = 257 bits (656), Expect = 2e-68
Identities = 163/433 (37%), Positives = 237/433 (54%), Gaps = 62/433 (14%)
Query: 128 EYFFDRNRPSFDGILYYYQSGGKIRRPANVPIDIFADEISFYEL---------------- 171
E+FFDR+ F +L YY++G K+ PA+V +F +E++F+ +
Sbjct: 101 EFFFDRHPGVFAYVLNYYRTG-KLHCPADVCGPLFEEELAFWGIDETDVEPCCWMTYRQH 159
Query: 172 --GSEAMDQFREDEGFIKDP---ETL----LPTND----------------IHRQFWLLF 206
EA+D F + DP E L L D + + W LF
Sbjct: 160 RDAEEALDIFETPDLIGGDPGDDEDLAAKRLGIEDAAGLGGPDGKSGRWRRLQPRMWALF 219
Query: 207 EYPESSSAARAVAVVSVLVVVISITIFCLETLPEFREDRELKVVRDPNLNMSKTVLSQTM 266
E P SS AAR +A S+ +++SIT FCLET F +K +P +N + VL +
Sbjct: 220 EDPYSSRAARFIAFASLFFILVSITTFCLETHEAFNI---VKNKTEPVINGTSVVLQYEI 276
Query: 267 FTDPFFM-VESTCIVWFTFELVLRFVVCPSKTDFFRNIMNIIDIISIIPYFATLITELVQ 325
TDP VE C+VWFTFE ++R V P+K +F +N++NIID ++I+P++ E+
Sbjct: 277 ETDPALTYVEGVCVVWFTFEFLVRIVFSPNKLEFIKNLLNIIDFVAILPFYL----EVGL 332
Query: 326 ETEPSAQQNMSLAILRIIRLVRVFRIFKLSRHSKGLQILGQTLKASMRELGLLIFFLFIG 385
S L LR++R VR+ RIFKL+RH GL++LG TL+AS E LLI FL +G
Sbjct: 333 SGLSSKAAKDVLGFLRVVRFVRILRIFKLTRHFVGLRVLGHTLRASTNEFLLLIIFLALG 392
Query: 386 VILFSSAVYFAE-----VDEPES----HFSSIPDGFWWAVVTMTTVGYGDMCPTTPGGKI 436
V++F++ +Y+AE ++P + F +IP GFWWAVVTMTT+GYGDM P T G +
Sbjct: 393 VLIFATMIYYAERVGAQPNDPSASEHTQFKNIPIGFWWAVVTMTTLGYGDMYPQTWSGML 452
Query: 437 VGTLCAIAGVLTIALPVPVIVSNFNYFYHRETENEEKQNIPGEIERILNSVGSRMGSTDS 496
VG LCA+AGVLTIA+PVPVIV+NF +Y KQ +P + ++ + T
Sbjct: 453 VGALCALAGVLTIAMPVPVIVNNFGMYYSLAM---AKQKLPRKRKKHIPPAPQASSPTFC 509
Query: 497 LNKTNGGCSTEKS 509
+ N C++ +S
Sbjct: 510 KTELNMACNSTQS 522
Score = 32.3 bits (72), Expect = 1.1
Identities = 15/30 (50%), Positives = 18/30 (60%)
Query: 83 EGNQRVIINIAGLRFETQLRTLSQFPETLL 112
E N+RVI+N+ G R ET TL P T L
Sbjct: 5 ENNERVILNVGGTRHETYRSTLKTLPGTRL 34
>gi|9789987 potassium voltage-gated channel, Shal-related subfamily,
member 2 [Homo sapiens]
Length = 630
Score = 256 bits (655), Expect = 3e-68
Identities = 148/421 (35%), Positives = 242/421 (57%), Gaps = 43/421 (10%)
Query: 75 GPEPVVLNEGNQR-----VIINIAGLRFETQLRTLSQFPETLLGDREKRMQFFDSMRNEY 129
GP P + +R +++N++G RF+T TL ++P+TLLG E+ F+ +Y
Sbjct: 25 GPMPAPPRQERKRTQDALIVLNVSGTRFQTWQDTLERYPDTLLGSSERDF-FYHPETQQY 83
Query: 130 FFDRNRPSFDGILYYYQSGGKIRRPANVPIDIFADEISFYELGSEAM---------DQFR 180
FFDR+ F IL +Y++G K+ P + I + +E++F+ L E + D+ R
Sbjct: 84 FFDRDPDIFRHILNFYRTG-KLHYPRHECISAYDEELAFFGLIPEIIGDCCYEEYKDRRR 142
Query: 181 EDEGFIKDP-------ETLLPTNDIHRQFWLLFEYPESSSAARAVAVVSVLVVVISITIF 233
E+ ++D E+ LPT ++ W FE P +S+ A V+ + +S+
Sbjct: 143 ENAERLQDDADTDTAGESALPTMTARQRVWRAFENPHTSTMALVFYYVTGFFIAVSVIAN 202
Query: 234 CLETLPEFREDRELKVVRDPNLNMSKTVLSQTMFTDPFFMVESTCIVWFTFELVLRFVVC 293
+ET+P +K + + FF +++ C++ FT E +LR
Sbjct: 203 VVETVPCGSSPGHIKELP-----------CGERYAVAFFCLDTACVMIFTVEYLLRLAAA 251
Query: 294 PSKTDFFRNIMNIIDIISIIPYFATLITELVQETEPSAQQNMSLAILRIIRLVRVFRIFK 353
PS+ F R++M+IID+++I+PY+ L+ + +++S A + + R+ RVFRIFK
Sbjct: 252 PSRYRFVRSVMSIIDVVAILPYYIGLVM--------TDNEDVSGAFVTL-RVFRVFRIFK 302
Query: 354 LSRHSKGLQILGQTLKASMRELGLLIFFLFIGVILFSSAVYFAEVDEPESHFSSIPDGFW 413
SRHS+GL+ILG TLK+ ELG L+F L + +I+F++ +++AE S F+SIP FW
Sbjct: 303 FSRHSQGLRILGYTLKSCASELGFLLFSLTMAIIIFATVMFYAEKGSSASKFTSIPAAFW 362
Query: 414 WAVVTMTTVGYGDMCPTTPGGKIVGTLCAIAGVLTIALPVPVIVSNFNYFYHRETENEEK 473
+ +VTMTT+GYGDM P T GKI G++C+++GVL IALPVPVIVSNF+ YH+ +++
Sbjct: 363 YTIVTMTTLGYGDMVPKTIAGKIFGSICSLSGVLVIALPVPVIVSNFSRIYHQNQRADKR 422
Query: 474 Q 474
+
Sbjct: 423 R 423
>gi|45383011 potassium voltage-gated channel, delayed-rectifier,
subfamily S, member 2 [Homo sapiens]
Length = 477
Score = 247 bits (631), Expect = 2e-65
Identities = 147/432 (34%), Positives = 232/432 (53%), Gaps = 62/432 (14%)
Query: 82 NEGNQRVIINIAGLRFETQLRTLSQFPETLLG------DREKRMQF---FDSMRNEYFFD 132
N + + IN+ G + + TL +FPET LG RE ++ +D ++ E++FD
Sbjct: 13 NVEDGEIRINVGGFKRRLRSHTLLRFPETRLGRLLLCHSREAILELCDDYDDVQREFYFD 72
Query: 133 RNRPSFDGILYYYQSGGKIRRPANVPIDIFADEISFYELGS------------------- 173
RN F +L++Y +G K+ A + + F+ EI ++ +
Sbjct: 73 RNPELFPYVLHFYHTG-KLHVMAELCVFSFSQEIEYWGINEFFIDSCCSYSYHGRKVEPE 131
Query: 174 -EAMDQFREDEGFIKDPETLL------------PTNDIHRQFWLLFEYPESSSAARAVAV 220
E D+ + E + +L P + RQ WL + P S +R ++
Sbjct: 132 QEKWDEQSDQESTTSSFDEILAFYNDASKFDGQPLGNFRRQLWLALDNPGYSVLSRVFSI 191
Query: 221 VSVLVVVISITIFCLETLPEFR-EDRELKVVRDPNLNMSKTVLSQTMFTDPFFMVESTCI 279
+S+LVV+ SI CL +LP+F+ D + DP F +VE I
Sbjct: 192 LSILVVMGSIITMCLNSLPDFQIPDSQGNPGEDPR----------------FEIVEHFGI 235
Query: 280 VWFTFELVLRFVVCPSKTDFFRNIMNIIDIISIIPYFATLITELVQETEPSAQQNMSLAI 339
WFTFELV RF V P FF+N +N+ID++SI+P++ TL+ LV E+ P+ +A
Sbjct: 236 AWFTFELVARFAVAPDFLKFFKNALNLIDLMSIVPFYITLVVNLVVESTPTLANLGRVA- 294
Query: 340 LRIIRLVRVFRIFKLSRHSKGLQILGQTLKASMRELGLLIFFLFIGVILFSSAVYFAEVD 399
+++RL+R+FRI KL+RHS GL+ LG TLK S +E+GLL+ +L +G+ +FS Y E +
Sbjct: 295 -QVLRLMRIFRILKLARHSTGLRSLGATLKYSYKEVGLLLLYLSVGISIFSVVAYTIEKE 353
Query: 400 EPESHFSSIPDGFWWAVVTMTTVGYGDMCPTTPGGKIVGTLCAIAGVLTIALPVPVIVSN 459
E E ++IP +WWA V+MTTVGYGD+ P T GK+ + C +AG+L + LP+ +I +
Sbjct: 354 ENEG-LATIPACWWWATVSMTTVGYGDVVPGTTAGKLTASACILAGILVVVLPITLIFNK 412
Query: 460 FNYFYHRETENE 471
F++FY R+ + E
Sbjct: 413 FSHFYRRQKQLE 424
>gi|24497460 Shaw-related voltage-gated potassium channel protein 3
[Homo sapiens]
Length = 757
Score = 234 bits (597), Expect = 1e-61
Identities = 125/274 (45%), Positives = 173/274 (63%), Gaps = 16/274 (5%)
Query: 203 WLLFEYPESSSAARAVAVVSVLVVVISITIFCLETLPEFREDRELKVVRDPNLNMS--KT 260
W LFE P SS AAR VA S+ ++ISIT FCLET F V + + + +
Sbjct: 277 WALFEDPYSSRAARYVAFASLFFILISITTFCLETHEGFIHISNKTVTQASPIPGAPPEN 336
Query: 261 VLSQTMFTDPFFM-VESTCIVWFTFELVLRFVVCPSKTDFFRNIMNIIDIISIIPYFATL 319
+ + + T+PF VE C+VWFTFE ++R CP K +F ++ +NIID ++I+P++
Sbjct: 337 ITNVEVETEPFLTYVEGVCVVWFTFEFLMRITFCPDKVEFLKSSLNIIDCVAILPFYL-- 394
Query: 320 ITELVQETEPSAQQNMSLAILRIIRLVRVFRIFKLSRHSKGLQILGQTLKASMRELGLLI 379
E+ S L LR++R VR+ RIFKL+RH GL++LG TL+AS E LLI
Sbjct: 395 --EVGLSGLSSKAAKDVLGFLRVVRFVRILRIFKLTRHFVGLRVLGHTLRASTNEFLLLI 452
Query: 380 FFLFIGVILFSSAVYFAE---------VDEPESHFSSIPDGFWWAVVTMTTVGYGDMCPT 430
FL +GV++F++ +Y+AE + ++F +IP GFWWAVVTMTT+GYGDM P
Sbjct: 453 IFLALGVLIFATMIYYAERIGADPDDILGSNHTYFKNIPIGFWWAVVTMTTLGYGDMYPK 512
Query: 431 TPGGKIVGTLCAIAGVLTIALPVPVIVSNFNYFY 464
T G +VG LCA+AGVLTIA+PVPVIV+NF +Y
Sbjct: 513 TWSGMLVGALCALAGVLTIAMPVPVIVNNFGMYY 546
Score = 52.0 bits (123), Expect = 1e-06
Identities = 31/87 (35%), Positives = 51/87 (58%), Gaps = 5/87 (5%)
Query: 87 RVIINIAGLRFETQLRTLSQFPETLLG---DREKRMQF-FDSMRNEYFFDRNRPSFDGIL 142
+++IN+ G+R ET TL P T L + E +F +D +E+FFDR+ F +L
Sbjct: 89 KIVINVGGVRHETYRSTLRTLPGTRLAGLTEPEAAARFDYDPGADEFFFDRHPGVFAYVL 148
Query: 143 YYYQSGGKIRRPANVPIDIFADEISFY 169
YY++ GK+ PA+V +F +E+ F+
Sbjct: 149 NYYRT-GKLHCPADVCGPLFEEELGFW 174
>gi|25952108 potassium voltage-gated channel delayed-rectifier
protein S3 [Homo sapiens]
Length = 491
Score = 227 bits (579), Expect = 2e-59
Identities = 145/449 (32%), Positives = 227/449 (50%), Gaps = 71/449 (15%)
Query: 68 GDYADPPGPEPVVLNEGNQRVIINIAGLRFETQLRTLSQFPETLLG------DREKRMQF 121
G++ PG + ++N +N+ G + TL +FP T LG E ++
Sbjct: 4 GEFFHRPGQDEELVN-------LNVGGFKQSVDQSTLLRFPHTRLGKLLTCHSEEAILEL 56
Query: 122 FDSMR---NEYFFDRNRPSFDGILYYYQSGGKIRRPANVPIDIFADEISFYELGSEAMDQ 178
D EY+FDRN F +L +Y +G K+ + + F EI ++ + +D
Sbjct: 57 CDDYSVADKEYYFDRNPSLFRYVLNFYYTG-KLHVMEELCVFSFCQEIEYWGINELFIDS 115
Query: 179 ------------------------------FREDEGFIKDPETL--LPTNDIHRQFWLLF 206
F E F K+ E L + ++ W+
Sbjct: 116 CCSNRYQERKEENHEKDWDQKSHDVSTDSSFEESSLFEKELEKFDTLRFGQLRKKIWIRM 175
Query: 207 EYPESSSAARAVAVVSVLVVVISITIFCLETLPEFR-EDRELKVVRDPNLNMSKTVLSQT 265
E P +A+ +A+ S+ VV+ SI C+ ++ EF+ ED E V DP L
Sbjct: 176 ENPAYCLSAKLIAISSLSVVLASIVAMCVHSMSEFQNEDGE---VDDPVLEG-------- 224
Query: 266 MFTDPFFMVESTCIVWFTFELVLRFVVCPSKTDFFRNIMNIIDIISIIPYFATLITELVQ 325
VE CI WFT EL +R P + F++N +NIID +SIIP++ATL + +
Sbjct: 225 --------VEIACIAWFTGELAVRLAAAPCQKKFWKNPLNIIDFVSIIPFYATLAVD-TK 275
Query: 326 ETEPSAQQNMSLAILRIIRLVRVFRIFKLSRHSKGLQILGQTLKASMRELGLLIFFLFIG 385
E E +NM +++I+RL+R+FRI KL+RHS GL+ LG TL+ S E+GLL+ FL +G
Sbjct: 276 EEESEDIENMG-KVVQILRLMRIFRILKLARHSVGLRSLGATLRHSYHEVGLLLLFLSVG 334
Query: 386 VILFSSAVYFAEVDEPESHFSSIPDGFWWAVVTMTTVGYGDMCPTTPGGKIVGTLCAIAG 445
+ +FS +Y E D+ S +SIP +WWA ++MTTVGYGD P T GK++ + C I G
Sbjct: 335 ISIFSVLIYSVEKDDHTSSLTSIPICWWWATISMTTVGYGDTHPVTLAGKLIASTCIICG 394
Query: 446 VLTIALPVPVIVSNFNYFYHRETENEEKQ 474
+L +ALP+ +I + F+ +Y ++ + + Q
Sbjct: 395 ILVVALPITIIFNKFSKYYQKQKDIDVDQ 423
>gi|13492973 potassium voltage-gated channel delayed-rectifier
protein S1 [Homo sapiens]
Length = 526
Score = 224 bits (570), Expect = 2e-58
Identities = 137/459 (29%), Positives = 242/459 (52%), Gaps = 51/459 (11%)
Query: 74 PGPEPVVL-NEGNQRVIINIAGLRFETQLRTLSQFPETLLG--------DREKRM-QFFD 123
PGP+ + ++ + +N+ G+R + R L++FP T LG ++ +R+ +D
Sbjct: 37 PGPDTGIRWRRSDEALRVNVGGVRRQLSARALARFPGTRLGRLQAAASEEQARRLCDDYD 96
Query: 124 SMRNEYFFDRNRPSFDGILYYYQSGGKIRRPANVPIDIFADEISFYELGSEAMD------ 177
E++FDR+ F +L++Y++G + + + F E ++ LG A+
Sbjct: 97 EAAREFYFDRHPGFFLSLLHFYRTG-HLHVLDELCVFAFGQEADYWGLGENALAACCRAR 155
Query: 178 ----QFREDEGFIKD---PETLLPTND-------------------IHRQFWLLFEYPES 211
+ + + +D P ++ P D + R+ WL E P
Sbjct: 156 YLERRLTQPHAWDEDSDTPSSVDPCPDEISDVQRELARYGAARCGRLRRRLWLTMENPGY 215
Query: 212 SSAARAVAVVSVLVVVISITIFCLETLPEFREDRELKVVRDPNLNMSKTVLSQTMFTDPF 271
S ++ + VS+ VV+ SI C+ +LPE++ V S + + DP
Sbjct: 216 SLPSKLFSCVSISVVLASIAAMCIHSLPEYQAREAAAAVAAVAAGRSP----EGVRDDPV 271
Query: 272 FM-VESTCIVWFTFELVLRFVVCPSKTDFFRNIMNIIDIISIIPYFATLITELVQETEPS 330
+E CI WF+FE+ R ++ PS +FF + +N+IDI+S++P++ TL+ + +
Sbjct: 272 LRRLEYFCIAWFSFEVSSRLLLAPSTRNFFCHPLNLIDIVSVLPFYLTLLAGVALGDQGG 331
Query: 331 AQQNMSLAILRIIRLVRVFRIFKLSRHSKGLQILGQTLKASMRELGLLIFFLFIGVILFS 390
+ ++++ RL+R+FR+ KL+RHS GL+ LG TLK S RE+G+L+ +L +GV +FS
Sbjct: 332 KEFGHLGKVVQVFRLMRIFRVLKLARHSTGLRSLGATLKHSYREVGILLLYLAVGVSVFS 391
Query: 391 SAVYFAEVDEPESHFSSIPDGFWWAVVTMTTVGYGDMCPTTPGGKIVGTLCAIAGVLTIA 450
Y AE +E + F++IP +WW V+MTTVGYGD+ P T GK+ + C + G+L +A
Sbjct: 392 GVAYTAEKEE-DVGFNTIPACWWWGTVSMTTVGYGDVVPVTVAGKLAASGCILGGILVVA 450
Query: 451 LPVPVIVSNFNYFYHRE--TENEEKQNIPGEIERILNSV 487
LP+ +I + F++FY R+ E + + E E +L+S+
Sbjct: 451 LPITIIFNKFSHFYRRQKALEAAVRNSNHQEFEDLLSSI 489
>gi|20070166 potassium voltage-gated channel, subfamily F, member 1
[Homo sapiens]
Length = 494
Score = 219 bits (557), Expect = 6e-57
Identities = 142/448 (31%), Positives = 226/448 (50%), Gaps = 66/448 (14%)
Query: 88 VIINIAGLRFETQLRTLSQFPETLLGDREKRM-----------QFFDSMRNEYFFDRNRP 136
+++N+ G+R LSQ+PET L + + +D + E++FDR+
Sbjct: 25 IVVNVGGVRQVLYGDLLSQYPETRLAELINCLAGGYDTIFSLCDDYDPGKREFYFDRDPD 84
Query: 137 SFDGILYYYQSGGKIRRPANVPIDIFADEISFYELGSEAMD--------QFRED-EGFIK 187
+F ++ Y G + PI F +E+ F+++ + +D + RE+ E +
Sbjct: 85 AFKCVIEVYYFGEVHMKKGICPI-CFKNEMDFWKVDLKFLDDCCKSHLSEKREELEEIAR 143
Query: 188 DPETLLPTNDI----------HRQFWLLFEYPESSSAARAVAVVSVLVVVISITIFCLET 237
+ +L + + W E PESS AR VAV+S L++++S + C+ T
Sbjct: 144 RVQLILDDLGVDAAEGRWRRCQKCVWKFLEKPESSCPARVVAVLSFLLILVSSVVMCMGT 203
Query: 238 LPEFRE-DRELKVVRDPNLNMSKTVLSQTMFTDPFFMVESTCIVWFTFELVLRFVVCPSK 296
+PE + D E V P L VE+ CI WFT E +LR P+K
Sbjct: 204 IPELQVLDAEGNRVEHPTLEN----------------VETACIGWFTLEYLLRLFSSPNK 247
Query: 297 TDFFRNIMNIIDIISIIPYFATL-ITELVQETEPSAQQNMSLAILRIIRLVRVFRIFKLS 355
F + MNI+D+++I+P++ +L +T L ++ LRI+R+ R IFKL+
Sbjct: 248 LHFALSFMNIVDVLAILPFYVSLTLTHLGARMMELTNVQQAVQALRIMRIAR---IFKLA 304
Query: 356 RHSKGLQILGQTLKASMRELGLLIFFLFIGVILFSSAVYFAEVDEPESHFSSIPDGFWWA 415
RHS GLQ L LK S +ELGLL+ +L +G+ +FS+ Y E PE+ F SIP FWWA
Sbjct: 305 RHSSGLQTLTYALKRSFKELGLLLMYLAVGIFVFSALGYTMEQSHPETLFKSIPQSFWWA 364
Query: 416 VVTMTTVGYGDMCPTTPGGKIVGTLCAIAGVLTIALPVPVIVSNFNYFYHRETENEEKQN 475
++TMTTVGYGD+ P T GK+ + + GV+ IALP+ I++NF +Y++
Sbjct: 365 IITMTTVGYGDIYPKTTLGKLNAAISFLCGVIAIALPIHPIINNFVRYYNK--------- 415
Query: 476 IPGEIERILNSVGSRMGSTDSLNKTNGG 503
+R+L + LN ++GG
Sbjct: 416 -----QRVLETAAKHELELMELNSSSGG 438
>gi|7657289 potassium channel, subfamily V, member 1 [Homo sapiens]
Length = 500
Score = 214 bits (544), Expect = 2e-55
Identities = 139/460 (30%), Positives = 226/460 (49%), Gaps = 69/460 (15%)
Query: 47 SNGKILISESTNHETAFSKLPGDYADPPGPEPVVLNEGNQRVIINIAGLRFETQLRTLSQ 106
S+G+ L+ + + S + EP+ L + +N+ G RF + LS
Sbjct: 3 SSGRALLDSPLDSGSLTSLDSSVFCSEGEGEPLALGDC---FTVNVGGSRFVLSQQALSC 59
Query: 107 FPETLLGDREKRMQFF-------------------DSMRNEYFFDRNRPSFDGILYYYQS 147
FP T LG + + + + NEYFFDR+ +F +L+YY++
Sbjct: 60 FPHTRLGKLAVVVASYRRPGALAAVPSPLELCDDANPVDNEYFFDRSSQAFRYVLHYYRT 119
Query: 148 GGKIRRPANVPIDIFADEISFYELGSEAMDQ------FREDE-----GFIKDPE------ 190
G ++ + F EI ++ + ++D FR E F KD E
Sbjct: 120 G-RLHVMEQLCALSFLQEIQYWGIDELSIDSCCRDRYFRRKELSETLDFKKDTEDQESQH 178
Query: 191 ------TLLPTNDIHRQFWLLFEYPESSSAARAVAVVSVLVVVISITIFCLETLPEFRED 244
+ P + ++ W + E P SS+AAR V+S++ VV+SI L + D
Sbjct: 179 ESEQDFSQGPCPTVRQKLWNILEKPGSSTAARIFGVISIIFVVVSIINMALMSAELSWLD 238
Query: 245 RELKVVRDPNLNMSKTVLSQTMFTDPFFMVESTCIVWFTFELVLRFVVCPSKTDFFRNIM 304
+L + +E CI WFT E VLRF+ + F R +
Sbjct: 239 LQLLEI-----------------------LEYVCISWFTGEFVLRFLCVRDRCRFLRKVP 275
Query: 305 NIIDIISIIPYFATLITELVQETEPSAQQNMSLAILRIIRLVRVFRIFKLSRHSKGLQIL 364
NIID+++I+P++ TL+ E + ++ + + I++++RL+R R+ KL RHS GL+ L
Sbjct: 276 NIIDLLAILPFYITLLVESLSGSQTTQELENVGRIVQVLRLLRALRMLKLGRHSTGLRSL 335
Query: 365 GQTLKASMRELGLLIFFLFIGVILFSSAVYFAEVDEPESHFSSIPDGFWWAVVTMTTVGY 424
G T+ E+GLL+ FL +G+ +FS+ YFAE P++ F+S+P +WWA +MTTVGY
Sbjct: 336 GMTITQCYEEVGLLLLFLSVGISIFSTVEYFAEQSIPDTTFTSVPCAWWWATTSMTTVGY 395
Query: 425 GDMCPTTPGGKIVGTLCAIAGVLTIALPVPVIVSNFNYFY 464
GD+ P T GKIV +C ++G+L +ALP+ +I F+ Y
Sbjct: 396 GDIRPDTTTGKIVAFMCILSGILVLALPIAIINDRFSACY 435
>gi|19071574 potassium voltage-gated channel, subfamily G, member 3
isoform 1 [Homo sapiens]
Length = 436
Score = 211 bits (538), Expect = 1e-54
Identities = 133/418 (31%), Positives = 217/418 (51%), Gaps = 43/418 (10%)
Query: 84 GNQRVIINIAGLRFETQLRTLSQFP----ETLLGDREKR-----MQFFDSMRNEYFFDRN 134
G V++N+ G R+ L FP L G R +R +D RNEYFFDR+
Sbjct: 7 GAASVVLNVGGARYSLSRELLKDFPLRRVSRLHGCRSERDVLEVCDDYDRERNEYFFDRH 66
Query: 135 RPSFDGILYYYQSGGKIRRPANVPIDIFADEISFYELGSEAM---------DQFREDEGF 185
+F IL Y + GK+R + F +E+ ++ L + D+ + F
Sbjct: 67 SEAFGFILLYVRGHGKLRFAPRMCELSFYNEMIYWGLEGAHLEYCCQRRLDDRMSDTYTF 126
Query: 186 IKDPETLLPTNDIHR---------QFWL-----LFEYPESSSAARAVAVVSVLVVVISIT 231
E + D R + WL FE P SS AA+ +A VSV+ V++S+
Sbjct: 127 YSADEPGVLGRDEARPGGAEAAPSRRWLERMRRTFEEPTSSLAAQILASVSVVFVIVSMV 186
Query: 232 IFCLETLPEFREDRELKVVRDPNLNMSKTVLSQTMFTDPFFMVESTCIVWFTFELVLRFV 291
+ C TLP++R D ++ S +P ++E+ CI WFT E ++RF+
Sbjct: 187 VLCASTLPDWRN-----AAADNRSLDDRSRYSAGPGREPSGIIEAICIGWFTAECIVRFI 241
Query: 292 VCPSKTDFFRNIMNIIDIISIIPYFATLITELVQETEPSAQQNMSLAILRIIRLVRVFRI 351
V +K +F + +NIID+++I PY+ +++ + T ++Q + LR++R++R+F +
Sbjct: 242 VSKNKCEFVKRPLNIIDLLAITPYYISVLMTVF--TGENSQLQRAGVTLRVLRMMRIFWV 299
Query: 352 FKLSRHSKGLQILGQTLKASMRELGLLIFFLFIGVILFSSAVYFAE----VDEPESHFSS 407
KL+RH GLQ LG TLK RE+ +L+ F+ + + +FS+ E ++ F+S
Sbjct: 300 IKLARHFIGLQTLGLTLKRCYREMVMLLVFICVAMAIFSALSQLLEHGLDLETSNKDFTS 359
Query: 408 IPDGFWWAVVTMTTVGYGDMCPTTPGGKIVGTLCAIAGVLTIALPVPVIVSNFNYFYH 465
IP WW +++MTTVGYGDM P T G+I+G +C ++G++ +ALP+ I +F YH
Sbjct: 360 IPAACWWVIISMTTVGYGDMYPITVPGRILGGVCVVSGIVLLALPITFIYHSFVQCYH 417
>gi|27436993 potassium voltage-gated channel, subfamily G, member 3
isoform 2 [Homo sapiens]
Length = 425
Score = 208 bits (529), Expect = 1e-53
Identities = 131/418 (31%), Positives = 212/418 (50%), Gaps = 54/418 (12%)
Query: 84 GNQRVIINIAGLRFETQLRTLSQFP----ETLLGDREKR-----MQFFDSMRNEYFFDRN 134
G V++N+ G R+ L FP L G R +R +D RNEYFFDR+
Sbjct: 7 GAASVVLNVGGARYSLSRELLKDFPLRRVSRLHGCRSERDVLEVCDDYDRERNEYFFDRH 66
Query: 135 RPSFDGILYYYQSGGKIRRPANVPIDIFADEISFYELGSEAM---------DQFREDEGF 185
+F IL Y + GK+R + F +E+ ++ L + D+ + F
Sbjct: 67 SEAFGFILLYVRGHGKLRFAPRMCELSFYNEMIYWGLEGAHLEYCCQRRLDDRMSDTYTF 126
Query: 186 IKDPETLLPTNDIHR---------QFWL-----LFEYPESSSAARAVAVVSVLVVVISIT 231
E + D R + WL FE P SS AA+ +A VSV+ V++S+
Sbjct: 127 YSADEPGVLGRDEARPGGAEAAPSRRWLERMRRTFEEPTSSLAAQILASVSVVFVIVSMV 186
Query: 232 IFCLETLPEFREDRELKVVRDPNLNMSKTVLSQTMFTDPFFMVESTCIVWFTFELVLRFV 291
+ C TLP++R D ++E+ CI WFT E ++RF+
Sbjct: 187 VLCASTLPDWRN----------------AAADNRSLDDRSRIIEAICIGWFTAECIVRFI 230
Query: 292 VCPSKTDFFRNIMNIIDIISIIPYFATLITELVQETEPSAQQNMSLAILRIIRLVRVFRI 351
V +K +F + +NIID+++I PY+ +++ + T ++Q + LR++R++R+F +
Sbjct: 231 VSKNKCEFVKRPLNIIDLLAITPYYISVLMTVF--TGENSQLQRAGVTLRVLRMMRIFWV 288
Query: 352 FKLSRHSKGLQILGQTLKASMRELGLLIFFLFIGVILFSSAVYFAE----VDEPESHFSS 407
KL+RH GLQ LG TLK RE+ +L+ F+ + + +FS+ E ++ F+S
Sbjct: 289 IKLARHFIGLQTLGLTLKRCYREMVMLLVFICVAMAIFSALSQLLEHGLDLETSNKDFTS 348
Query: 408 IPDGFWWAVVTMTTVGYGDMCPTTPGGKIVGTLCAIAGVLTIALPVPVIVSNFNYFYH 465
IP WW +++MTTVGYGDM P T G+I+G +C ++G++ +ALP+ I +F YH
Sbjct: 349 IPAACWWVIISMTTVGYGDMYPITVPGRILGGVCVVSGIVLLALPITFIYHSFVQCYH 406
Database: hs.faa
Posted date: Aug 4, 2009 4:42 PM
Number of letters in database: 18,247,518
Number of sequences in database: 37,866
Lambda K H
0.322 0.139 0.410
Gapped
Lambda K H
0.267 0.0410 0.140
Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Hits to DB: 19,630,736
Number of Sequences: 37866
Number of extensions: 916603
Number of successful extensions: 2641
Number of sequences better than 10.0: 30
Number of HSP's better than 10.0 without gapping: 158
Number of HSP's successfully gapped in prelim test: 27
Number of HSP's that attempted gapping in prelim test: 2138
Number of HSP's gapped (non-prelim): 342
length of query: 511
length of database: 18,247,518
effective HSP length: 107
effective length of query: 404
effective length of database: 14,195,856
effective search space: 5735125824
effective search space used: 5735125824
T: 11
A: 40
X1: 16 ( 7.4 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 41 (21.9 bits)
S2: 64 (29.3 bits)
Search results were obtained with NCBI BLAST and RefSeq entries.
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Guide to the Human Genome
Copyright © 2010 by Stewart Scherer. All rights reserved.