Search of human proteins with 5031805

BLASTP 2.2.11 [Jun-05-2005]


Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer, 
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), 
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs",  Nucleic Acids Res. 25:3389-3402.

Query= gi|5031805 insulin receptor substrate 1 [Homo sapiens]
         (1242 letters)

Database: hs.faa 
           37,866 sequences; 18,247,518 total letters

Searching..................................................done

                                                                 Score    E
Sequences producing significant alignments:                      (bits) Value

gi|5031805 insulin receptor substrate 1 [Homo sapiens]               2544   0.0  
gi|38683860 insulin receptor substrate 2 [Homo sapiens]               691   0.0  
gi|4504733 insulin receptor substrate 4 [Homo sapiens]                317   4e-86
gi|55750053 atrophin-1 [Homo sapiens]                                  66   2e-10
gi|55750041 atrophin-1 [Homo sapiens]                                  66   2e-10
gi|239743293 PREDICTED: mucin 12 [Homo sapiens]                        60   1e-08
gi|239508976 PREDICTED: mucin 12, cell surface associated [Homo ...    59   2e-08
gi|209915594 transcription factor 3 isoform E47 [Homo sapiens]         54   1e-06
gi|27777636 transcription factor 3 isoform E12 [Homo sapiens]          54   1e-06
gi|118572613 splicing coactivator subunit SRm300 [Homo sapiens]        52   5e-06
gi|18105042 GRB2-associated binding protein 2 isoform a [Homo sa...    51   6e-06
gi|169658378 trinucleotide repeat containing 18 [Homo sapiens]         51   8e-06
gi|20070302 docking protein 4 [Homo sapiens]                           50   1e-05
gi|226509740 SR-related CTD-associated factor 1 [Homo sapiens]         50   2e-05
gi|239758148 PREDICTED: similar to mucin 11 [Homo sapiens]             49   2e-05
gi|158854042 hypothetical protein LOC222183 [Homo sapiens]             49   2e-05
gi|163965366 nascent polypeptide-associated complex alpha subuni...    49   2e-05
gi|239752490 PREDICTED: similar to Mucin-12 [Homo sapiens]             49   3e-05
gi|28559039 mediator complex subunit 1 [Homo sapiens]                  48   5e-05
gi|148806908 fibronectin type III domain containing 1 [Homo sapi...    48   5e-05
gi|46370073 GRB2-associated binding protein 1 isoform b [Homo sa...    47   9e-05
gi|46370071 GRB2-associated binding protein 1 isoform a [Homo sa...    47   9e-05
gi|4505939 DNA-directed RNA polymerase II A [Homo sapiens]             47   9e-05
gi|239752594 PREDICTED: hypothetical protein, partial [Homo sapi...    47   1e-04
gi|7662236 TSC22 domain family, member 2 [Homo sapiens]                47   1e-04
gi|83716021 GRB2-associated binding protein family, member 4 [Ho...    45   3e-04
gi|126091130 Gab3 protein isoform 1 [Homo sapiens]                     45   3e-04
gi|182765442 homeobox A10 isoform a [Homo sapiens]                     45   6e-04
gi|18079323 Gab3 protein isoform 2 [Homo sapiens]                      44   7e-04
gi|221139926 NHS-like 1 [Homo sapiens]                                 44   0.001

>gi|5031805 insulin receptor substrate 1 [Homo sapiens]
          Length = 1242

 Score = 2544 bits (6593), Expect = 0.0
 Identities = 1242/1242 (100%), Positives = 1242/1242 (100%)

Query: 1    MASPPESDGFSDVRKVGYLRKPKSMHKRFFVLRAASEAGGPARLEYYENEKKWRHKSSAP 60
            MASPPESDGFSDVRKVGYLRKPKSMHKRFFVLRAASEAGGPARLEYYENEKKWRHKSSAP
Sbjct: 1    MASPPESDGFSDVRKVGYLRKPKSMHKRFFVLRAASEAGGPARLEYYENEKKWRHKSSAP 60

Query: 61   KRSIPLESCFNINKRADSKNKHLVALYTRDEHFAIAADSEAEQDSWYQALLQLHNRAKGH 120
            KRSIPLESCFNINKRADSKNKHLVALYTRDEHFAIAADSEAEQDSWYQALLQLHNRAKGH
Sbjct: 61   KRSIPLESCFNINKRADSKNKHLVALYTRDEHFAIAADSEAEQDSWYQALLQLHNRAKGH 120

Query: 121  HDGAAALGAGGGGGSCSGSSGLGEAGEDLSYGDVPPGPAFKEVWQVILKPKGLGQTKNLI 180
            HDGAAALGAGGGGGSCSGSSGLGEAGEDLSYGDVPPGPAFKEVWQVILKPKGLGQTKNLI
Sbjct: 121  HDGAAALGAGGGGGSCSGSSGLGEAGEDLSYGDVPPGPAFKEVWQVILKPKGLGQTKNLI 180

Query: 181  GIYRLCLTSKTISFVKLNSEAAAVVLQLMNIRRCGHSENFFFIEVGRSAVTGPGEFWMQV 240
            GIYRLCLTSKTISFVKLNSEAAAVVLQLMNIRRCGHSENFFFIEVGRSAVTGPGEFWMQV
Sbjct: 181  GIYRLCLTSKTISFVKLNSEAAAVVLQLMNIRRCGHSENFFFIEVGRSAVTGPGEFWMQV 240

Query: 241  DDSVVAQNMHETILEAMRAMSDEFRPRSKSQSSSNCSNPISVPLRRHHLNNPPPSQVGLT 300
            DDSVVAQNMHETILEAMRAMSDEFRPRSKSQSSSNCSNPISVPLRRHHLNNPPPSQVGLT
Sbjct: 241  DDSVVAQNMHETILEAMRAMSDEFRPRSKSQSSSNCSNPISVPLRRHHLNNPPPSQVGLT 300

Query: 301  RRSRTESITATSPASMVGGKPGSFRVRASSDGEGTMSRPASVDGSPVSPSTNRTHAHRHR 360
            RRSRTESITATSPASMVGGKPGSFRVRASSDGEGTMSRPASVDGSPVSPSTNRTHAHRHR
Sbjct: 301  RRSRTESITATSPASMVGGKPGSFRVRASSDGEGTMSRPASVDGSPVSPSTNRTHAHRHR 360

Query: 361  GSARLHPPLNHSRSIPMPASRCSPSATSPVSLSSSSTSGHGSTSDCLFPRRSSASVSGSP 420
            GSARLHPPLNHSRSIPMPASRCSPSATSPVSLSSSSTSGHGSTSDCLFPRRSSASVSGSP
Sbjct: 361  GSARLHPPLNHSRSIPMPASRCSPSATSPVSLSSSSTSGHGSTSDCLFPRRSSASVSGSP 420

Query: 421  SDGGFISSDEYGSSPCDFRSSFRSVTPDSLGHTPPARGEEELSNYICMGGKGPSTLTAPN 480
            SDGGFISSDEYGSSPCDFRSSFRSVTPDSLGHTPPARGEEELSNYICMGGKGPSTLTAPN
Sbjct: 421  SDGGFISSDEYGSSPCDFRSSFRSVTPDSLGHTPPARGEEELSNYICMGGKGPSTLTAPN 480

Query: 481  GHYILSRGGNGHRCTPGTGLGTSPALAGDEAASAADLDNRFRKRTHSAGTSPTITHQKTP 540
            GHYILSRGGNGHRCTPGTGLGTSPALAGDEAASAADLDNRFRKRTHSAGTSPTITHQKTP
Sbjct: 481  GHYILSRGGNGHRCTPGTGLGTSPALAGDEAASAADLDNRFRKRTHSAGTSPTITHQKTP 540

Query: 541  SQSSVASIEEYTEMMPAYPPGGGSGGRLPGHRHSAFVPTRSYPEEGLEMHPLERRGGHHR 600
            SQSSVASIEEYTEMMPAYPPGGGSGGRLPGHRHSAFVPTRSYPEEGLEMHPLERRGGHHR
Sbjct: 541  SQSSVASIEEYTEMMPAYPPGGGSGGRLPGHRHSAFVPTRSYPEEGLEMHPLERRGGHHR 600

Query: 601  PDSSTLHTDDGYMPMSPGVAPVPSGRKGSGDYMPMSPKSVSAPQQIINPIRRHPQRVDPN 660
            PDSSTLHTDDGYMPMSPGVAPVPSGRKGSGDYMPMSPKSVSAPQQIINPIRRHPQRVDPN
Sbjct: 601  PDSSTLHTDDGYMPMSPGVAPVPSGRKGSGDYMPMSPKSVSAPQQIINPIRRHPQRVDPN 660

Query: 661  GYMMMSPSGGCSPDIGGGPSSSSSSSNAVPSGTSYGKLWTNGVGGHHSHVLPHPKPPVES 720
            GYMMMSPSGGCSPDIGGGPSSSSSSSNAVPSGTSYGKLWTNGVGGHHSHVLPHPKPPVES
Sbjct: 661  GYMMMSPSGGCSPDIGGGPSSSSSSSNAVPSGTSYGKLWTNGVGGHHSHVLPHPKPPVES 720

Query: 721  SGGKLLPCTGDYMNMSPVGDSNTSSPSDCYYGPEDPQHKPVLSYYSLPRSFKHTQRPGEP 780
            SGGKLLPCTGDYMNMSPVGDSNTSSPSDCYYGPEDPQHKPVLSYYSLPRSFKHTQRPGEP
Sbjct: 721  SGGKLLPCTGDYMNMSPVGDSNTSSPSDCYYGPEDPQHKPVLSYYSLPRSFKHTQRPGEP 780

Query: 781  EEGARHQHLRLSTSSGRLLYAATADDSSSSTSSDSLGGGYCGARLEPSLPHPHHQVLQPH 840
            EEGARHQHLRLSTSSGRLLYAATADDSSSSTSSDSLGGGYCGARLEPSLPHPHHQVLQPH
Sbjct: 781  EEGARHQHLRLSTSSGRLLYAATADDSSSSTSSDSLGGGYCGARLEPSLPHPHHQVLQPH 840

Query: 841  LPRKVDTAAQTNSRLARPTRLSLGDPKASTLPRAREQQQQQQPLLHPPEPKSPGEYVNIE 900
            LPRKVDTAAQTNSRLARPTRLSLGDPKASTLPRAREQQQQQQPLLHPPEPKSPGEYVNIE
Sbjct: 841  LPRKVDTAAQTNSRLARPTRLSLGDPKASTLPRAREQQQQQQPLLHPPEPKSPGEYVNIE 900

Query: 901  FGSDQSGYLSGPVAFHSSPSVRCPSQLQPAPREEETGTEEYMKMDLGPGRRAAWQESTGV 960
            FGSDQSGYLSGPVAFHSSPSVRCPSQLQPAPREEETGTEEYMKMDLGPGRRAAWQESTGV
Sbjct: 901  FGSDQSGYLSGPVAFHSSPSVRCPSQLQPAPREEETGTEEYMKMDLGPGRRAAWQESTGV 960

Query: 961  EMGRLGPAPPGAASICRPTRAVPSSRGDYMTMQMSCPRQSYVDTSPAAPVSYADMRTGIA 1020
            EMGRLGPAPPGAASICRPTRAVPSSRGDYMTMQMSCPRQSYVDTSPAAPVSYADMRTGIA
Sbjct: 961  EMGRLGPAPPGAASICRPTRAVPSSRGDYMTMQMSCPRQSYVDTSPAAPVSYADMRTGIA 1020

Query: 1021 AEEVSLPRATMAAASSSSAASASPTGPQGAAELAAHSSLLGGPQGPGGMSAFTRVNLSPN 1080
            AEEVSLPRATMAAASSSSAASASPTGPQGAAELAAHSSLLGGPQGPGGMSAFTRVNLSPN
Sbjct: 1021 AEEVSLPRATMAAASSSSAASASPTGPQGAAELAAHSSLLGGPQGPGGMSAFTRVNLSPN 1080

Query: 1081 RNQSAKVIRADPQGCRRRHSSETFSSTPSATRVGNTVPFGAGAAVGGGGGSSSSSEDVKR 1140
            RNQSAKVIRADPQGCRRRHSSETFSSTPSATRVGNTVPFGAGAAVGGGGGSSSSSEDVKR
Sbjct: 1081 RNQSAKVIRADPQGCRRRHSSETFSSTPSATRVGNTVPFGAGAAVGGGGGSSSSSEDVKR 1140

Query: 1141 HSSASFENVWLRPGELGGAPKEPAKLCGAAGGLENGLNYIDLDLVKDFKQCPQECTPEPQ 1200
            HSSASFENVWLRPGELGGAPKEPAKLCGAAGGLENGLNYIDLDLVKDFKQCPQECTPEPQ
Sbjct: 1141 HSSASFENVWLRPGELGGAPKEPAKLCGAAGGLENGLNYIDLDLVKDFKQCPQECTPEPQ 1200

Query: 1201 PPPPPPPHQPLGSGESSSTRRSSEDLSAYASISFQKQPEDRQ 1242
            PPPPPPPHQPLGSGESSSTRRSSEDLSAYASISFQKQPEDRQ
Sbjct: 1201 PPPPPPPHQPLGSGESSSTRRSSEDLSAYASISFQKQPEDRQ 1242


>gi|38683860 insulin receptor substrate 2 [Homo sapiens]
          Length = 1338

 Score =  691 bits (1783), Expect = 0.0
 Identities = 549/1384 (39%), Positives = 689/1384 (49%), Gaps = 301/1384 (21%)

Query: 13   VRKVGYLRKPKSMHKRFFVLRA-------ASEAGG----PARLEYYENEKKWRHKSSAPK 61
            VRK GYLRK K  HKRFFVLR        A+  GG    P RLEYYE+EKKWR K+ APK
Sbjct: 31   VRKCGYLRKQKHGHKRFFVLRGPGAGGDEATAGGGSAPQPPRLEYYESEKKWRSKAGAPK 90

Query: 62   RSIPLESCFNINKRADSKNKHLVALYTRDEHFAIAADSEAEQDSWYQALLQL--HNRAKG 119
            R I L+ C NINKRAD+K+K+L+ALYT+DE+FA+AA++E EQ+ WY+AL  L    RA  
Sbjct: 91   RVIALDCCLNINKRADAKHKYLIALYTKDEYFAVAAENEQEQEGWYRALTDLVSEGRAAA 150

Query: 120  HHDGAAALGAGGGGGSCSGSSG--LGEAGEDLSYGDVPPGPA-FKEVWQVILKPKGLGQT 176
                 AA  A     S  G+ G   G AG + SYG V P  A ++EVWQV LKPKGLGQ+
Sbjct: 151  GDAPPAAAPAASCSASLPGALGGSAGAAGAEDSYGLVAPATAAYREVWQVNLKPKGLGQS 210

Query: 177  KNLIGIYRLCLTSKTISFVKLNSEAAAVVLQLMNIRRCGHSENFFFIEVGRSAVTGPGEF 236
            KNL G+YRLCL+++TI FVKLN E  +V LQLMNIRRCGHS++FFFIEVGRSAVTGPGE 
Sbjct: 211  KNLTGVYRLCLSARTIGFVKLNCEQPSVTLQLMNIRRCGHSDSFFFIEVGRSAVTGPGEL 270

Query: 237  WMQVDDSVVAQNMHETILEAMRAMSD--EFRPRSKSQSS-SNCSNPISVP--LRRHHLNN 291
            WMQ DDSVVAQN+HETILEAM+A+ +  EFRPRSKSQSS S+ ++PISVP   R HHL N
Sbjct: 271  WMQADDSVVAQNIHETILEAMKALKELFEFRPRSKSQSSGSSATHPISVPGARRHHHLVN 330

Query: 292  PPPSQVGLTRRSRTESITATSPASMVGGKPGSFRVRASSDGEG--------TMSRPASVD 343
             PPSQ GL RRSRT+S+ AT PA+    K  S RVR +S+G+G          +RP SV 
Sbjct: 331  LPPSQTGLVRRSRTDSLAATPPAA----KCSSCRVRTASEGDGGAAAGAAAAGARPVSVA 386

Query: 344  GSPVSPSTNRTHAHRH---------RGSARLHPP----LNHSRSIPMPASRCSPSATSPV 390
            GSP+SP   R    R          RGS     P    L HSRS+ MP +   P+ATSP 
Sbjct: 387  GSPLSPGPVRAPLSRSHTLSGGCGGRGSKVALLPAGGALQHSRSMSMPVAHSPPAATSPG 446

Query: 391  SLSSSSTSGHGSTS------------------DCLFPRRSSASVSGSPSDGGFISSDEYG 432
            SLSSS  SGHGS S                      P   SAS SGSPSD GF+S DEYG
Sbjct: 447  SLSSS--SGHGSGSYPPPPGPHPPLPHPLHHGPGQRPSSGSASASGSPSDPGFMSLDEYG 504

Query: 433  SSPCDFRS--SFRSVTPDSLGHTPPAR---GEEELSNYICMGGKGPSTLTAPNGHYILSR 487
            SSP D R+  S RS TP+S+  TPPAR   G  E   Y+        T+  P     LS 
Sbjct: 505  SSPGDLRAFCSHRSNTPESIAETPPARDGGGGGEFYGYM--------TMDRP-----LSH 551

Query: 488  GGNGHRCTPGTGLGTSPALAGDEAASAADLDNRFRKRTHSAGTSPTITHQKTPSQSSVAS 547
             G  +R            ++GD   +A DLD   RKRT+S  T      Q+   Q S AS
Sbjct: 552  CGRSYR-----------RVSGD---AAQDLDRGLRKRTYSLTTP---ARQRPVPQPSSAS 594

Query: 548  IEEYTEMMPAYPPGGGSGGRL--PGHRHSAFVPTRSYPEEGLEMHPLERRGGHHRPDSST 605
            ++EYT M   +    GS GRL       S  V    YPE+  ++       G HR  SS 
Sbjct: 595  LDEYTLMRATF---SGSAGRLCPSCPASSPKVAYHPYPEDYGDIEI-----GSHRSSSSN 646

Query: 606  LHTDDGYMPMSPGVAPVPSGRKG--SGDYMPMSPKSVSAPQQIINP-----IRRHPQRVD 658
            L  DDGYMPM+PG A   SG     S DYMPMSP SVSAP+QI+ P              
Sbjct: 647  LGADDGYMPMTPGAALAGSGSGSCRSDDYMPMSPASVSAPKQILQPRAAAAAAAAVPSAG 706

Query: 659  PNGYMMMSPSGGCSPDIGGGPSSSSSSSNAVPSGTSYGKLWTNGVGGHHSHVLPHPKPPV 718
            P G    S +G   P  GGG  +SS + ++ P  + Y ++W               K  +
Sbjct: 707  PAGPAPTSAAGRTFPASGGGYKASSPAESS-PEDSGYMRMWCGS------------KLSM 753

Query: 719  ESSGGKLLPCTGDYMNMSPVGDSNTSSPSDCYYGPEDPQHKPV-----LSYYSLPRSFKH 773
            E + GKLLP  GDY+N+SP     T +P D +     P  +P+       Y SLPRS+K 
Sbjct: 754  EHADGKLLP-NGDYLNVSPSDAVTTGTPPDFFSAALHPGGEPLRGVPGCCYSSLPRSYKA 812

Query: 774  TQRPGEPEEGARHQHLRLSTSSGRLLYAATADDSSS---STSSDSLGGGYCGARLEPSLP 830
                G    G   Q++ +S+  GR+L     +  ++   S ++ + G G       P+ P
Sbjct: 813  PYTCG----GDSDQYVLMSSPVGRILEEERLEPQATPGPSQAASAFGAG-------PTQP 861

Query: 831  HPHHQVLQPHLPR--KVDTAAQTNSRLARPTRLSL-GDPKASTLPRAREQQQQQQPLLHP 887
             PH  V  P  P   + +       R  RPTRLSL G P   +LP   E      PL  P
Sbjct: 862  -PHPVVPSPVRPSGGRPEGFLGQRGRAVRPTRLSLEGLP---SLPSMHE-----YPL--P 910

Query: 888  PEPKSPGEYVNIEFGSDQSGYLSGPVAFHSSPSVRCPSQLQPAPREEETGT--------- 938
            PEPKSPGEY+NI+FG +    LS P     + +    S L  +      G+         
Sbjct: 911  PEPKSPGEYINIDFG-EPGARLSPPAPPLLASAASSSSLLSASSPASSLGSGTPGTSSDS 969

Query: 939  ------EEYMKMDLGPGRRAAWQESTGVEMGRLG-------------------------- 966
                   +YM +D    +       +G  +G L                           
Sbjct: 970  RQRSPLSDYMNLDFSSPKSPKPGAPSGHPVGSLDGLLSPEASSPYPPLPPRPSASPSSSL 1029

Query: 967  ---PAPPGAASICR--PTRAVPSSRGDYMTMQMSCPRQSYVDTSPAAPVSYADMRTGIAA 1021
               P PP    + R  P  AV +++G      +S       DT       Y +M  G+AA
Sbjct: 1030 QPPPPPPAPGELYRLPPASAVATAQGPGAASSLSS------DTGDNG--DYTEMAFGVAA 1081

Query: 1022 EEVSLPRATMAAASSSSAASASPTGPQGAAELAAHSSLLGGPQGPGGMSAFTRVNLSPNR 1081
               + P+   A     +A  ASPT   G   L+    +        G+ AF + +  P+ 
Sbjct: 1082 ---TPPQPIAAPPKPEAARVASPT--SGVKRLSLMEQV-------SGVEAFLQASQPPDP 1129

Query: 1082 NQSAKVIRADPQGCRRRHSSETFSSTPSATRVGNTVPFGAGAAVGGGGGSSSSSEDVKRH 1141
            ++ AKVIRADPQG RRRHSSETFSST + T V                 S S + + KRH
Sbjct: 1130 HRGAKVIRADPQGGRRRHSSETFSSTTTVTPV-----------------SPSFAHNPKRH 1172

Query: 1142 SSASFENVWLRPGELGG-------------------------------APKEPAKLCGAA 1170
            +SAS ENV LR    GG                                P +P  L G  
Sbjct: 1173 NSASVENVSLRKSSEGGVGVGPGGGDEPPTSPRQLQPAPPLAPQGRPWTPGQPGGLVGCP 1232

Query: 1171 G------------GLENGLNYIDLDLVKDFKQCPQECTPEPQPPPPPPPHQPLGSGESSS 1218
            G            G +NGLNYI +D V++    P    P+PQPPPPP P QP   G+ SS
Sbjct: 1233 GSGGSPMRRETSAGFQNGLNYIAID-VREEPGLP----PQPQPPPPPLP-QP---GDKSS 1283

Query: 1219 TRRS 1222
              R+
Sbjct: 1284 WGRT 1287


>gi|4504733 insulin receptor substrate 4 [Homo sapiens]
          Length = 1257

 Score =  317 bits (812), Expect = 4e-86
 Identities = 300/976 (30%), Positives = 414/976 (42%), Gaps = 203/976 (20%)

Query: 12  DVRKVGYLRKPKSMHKRFFVLRAASEAGGPARLEYYENEKKWRHKSSA------------ 59
           +V K GYLRK K  H+R+FVL+  + A  PARLEYYEN +K+RH   A            
Sbjct: 78  EVCKRGYLRKQKHGHRRYFVLKLET-ADAPARLEYYENARKFRHSVRAAAAAAAAAASGA 136

Query: 60  -------PKRSIPLESCFNINKRADSKNKHLVALYTRDEHFAIAADSEAEQDSWYQALLQ 112
                  P+R I L  CF++++RAD++ +HL+AL+T+DE+FA+ A++E+EQ+SWY  L +
Sbjct: 137 AIPPLIPPRRVITLYQCFSVSQRADARYRHLIALFTQDEYFAMVAENESEQESWYLLLSR 196

Query: 113 LHNRAKGHHDGAAALGAGGGGGSCSGSSGLGEAGEDLSYGDVPPGPAFKEVWQVILKPKG 172
           L   +K    G   LGA   G   +           L+       P +K+VWQVI+KP+G
Sbjct: 197 LILESKRRRCGT--LGAQPDGEPAA-----------LAAAAAAEPPFYKDVWQVIVKPRG 243

Query: 173 LGQTKNLIGIYRLCLTSKTISFVKLNSEAAAVVLQLMNIRRCGHSENFFFIEVGRSAVTG 232
           LG  K L G++RLCLT + + FV+LN+E A+VV+QL++IRRCGHSE +FF+EVGRS V G
Sbjct: 244 LGHRKELSGVFRLCLTDEEVVFVRLNTEVASVVVQLLSIRRCGHSEQYFFLEVGRSTVIG 303

Query: 233 PGEFWMQVDDSVVAQNMHETILEAMRAM-SDEFRPRSKSQSSSNCSNPISVPLRRHHLNN 291
           PGE WMQVDD VVAQNMHE  LE MRA+ +DE+R R +S S S  ++ +++   R HL  
Sbjct: 304 PGELWMQVDDCVVAQNMHELFLEKMRALCADEYRARCRSYSISIGAHLLTLLSARRHLGL 363

Query: 292 PPPSQVGLTRRSRTESITATSPASMVGGKPGSFRVRASSDGEGTM--SRPASVDGSPVSP 349
            P    G  RRSR E                   +RA  DGE  M  +R       PV  
Sbjct: 364 VPLEPGGWLRRSRFEQFC---------------HLRAIGDGEDEMLFTRRFVTPSEPV-- 406

Query: 350 STNRTHAHRHRGSARLHPPLNHSRSIPMPAS---RCSPSATSP---------VSLSSSST 397
                 AH  RG   L       R++ +PAS   R +PS   P          +  SS  
Sbjct: 407 ------AHSRRGRLHLPRGRRSRRAVSVPASFFRRLAPSPARPRHPAEAPNNGARLSSEV 460

Query: 398 SGHGS-----------------TSDCLFPRRSSASVSGSPSDGGFISSDEYGSSPCDFRS 440
           SG GS                 +     P  +  S +G  S GG  S+ +  SS     +
Sbjct: 461 SGSGSGNFGEEGNPQGKEDQEGSGGDYMPMNNWGSGNGRGSGGGQGSNGQGSSSHSSGGN 520

Query: 441 SFRSVTPDSLGHTPPARGEEELSNYICMGGKGPSTLTAPNGHYILSRGGNGHRCTPGTGL 500
                   S G    + G+    N     G+G +      G     R G GH    G G 
Sbjct: 521 QCSGEGQGSRG-GQGSNGQGSGGNQCSRDGQGTAGGHGSGGG---QRPGGGHGSGGGQGP 576

Query: 501 G---------TSPALAGDEAASAADLDNRFRKRTHSAGTSPTITHQKTPSQSSVASIEEY 551
           G          S    G  +   +D D    K          +T      QS    +   
Sbjct: 577 GDGHGSGGGKNSGGGKGSGSGKGSDGDGERGKSLKKRSYFGKLT------QSKQQQMPPP 630

Query: 552 TEMMPAYPPGGGSG--GRLPGHRHSAFVPTRSYPEEGLEMH-------PLERRGGHHRPD 602
               P  PP GG+G  G+  G     F   R   +E  E         P     G HR  
Sbjct: 631 PPPPPPPPPAGGTGGKGKSGGRFRLYFCVDRGATKECKEAKEVKDAEIPEGAARGPHRAR 690

Query: 603 SSTLHTDDGYMPMSPGVA-PVPSGRKGSGDYMPMSPKSVSAPQQIINPIRRHPQR--VDP 659
           +     DD Y+PM PGVA P+ S    S DYMPM+P++VSA +      +RH +    D 
Sbjct: 691 AFDEDEDDPYVPMRPGVATPLVS----SSDYMPMAPQNVSASK------KRHSRSPFEDS 740

Query: 660 NGYMMMSP--SGGCSPDIGGGPSSSSSSSNAVPSGTSYGKLWTNGVGGHHSHVLPHPKPP 717
            GYMMM P  S   +P     P ++    +      S       G G         PK P
Sbjct: 741 RGYMMMFPRVSPPPAPSPPKAPDTNKEDDSKDNDSESDYMFMAPGAGA-------IPKNP 793

Query: 718 VESSGGKLLPCTGDYMNM------SPVGDSNTSSPSDCYYGPEDPQHKPVLSYYSLPRSF 771
               GG        Y ++      SP+G ++ S            ++ P+L    L R  
Sbjct: 794 RNPQGGSSSKSWSSYFSLPNPFRSSPLGQNDNS------------EYVPMLPGKFLGRGL 841

Query: 772 -KHTQRPGEPEEGARHQHLRLSTSSGRLLYAATADDSSSSTSSDSLGGGYCGARLEPSLP 830
            K      +P++ A       S  SG   ++   D  S S  SD                
Sbjct: 842 DKEVSYNWDPKDAA-------SKPSGEGSFSKPGDGGSPSKPSD---------------- 878

Query: 831 HPHHQVLQPHLPRKVDTAAQTNSRLARPTRLSLGDPKASTLPRAREQQQQQQPLLHPPEP 890
                    H P K        ++  RP RLS         P+ ++   +Q+      E 
Sbjct: 879 ---------HEPPK--------NKAKRPNRLSFITKGYKIKPKPQKPTHEQR------EA 915

Query: 891 KSPGEYVNIEFGSDQS 906
            S  +YVN++F   +S
Sbjct: 916 DSSSDYVNMDFTKRES 931



 Score = 40.0 bits (92), Expect = 0.014
 Identities = 30/102 (29%), Positives = 35/102 (34%), Gaps = 8/102 (7%)

Query: 1120 GAGAAVGGGGGSSSSSEDVKRHSSASFENVWLRPGELGGAPKEPAKLCGAAGGLENGLNY 1179
            G G   GGG GS         H S   +N         G  K      G+ G  E G + 
Sbjct: 559  GGGQRPGGGHGSGGGQGPGDGHGSGGGKN--------SGGGKGSGSGKGSDGDGERGKSL 610

Query: 1180 IDLDLVKDFKQCPQECTPEPQPPPPPPPHQPLGSGESSSTRR 1221
                      Q  Q+  P P PPPPPPP      G+  S  R
Sbjct: 611  KKRSYFGKLTQSKQQQMPPPPPPPPPPPPAGGTGGKGKSGGR 652


>gi|55750053 atrophin-1 [Homo sapiens]
          Length = 1190

 Score = 65.9 bits (159), Expect = 2e-10
 Identities = 169/748 (22%), Positives = 244/748 (32%), Gaps = 123/748 (16%)

Query: 513  SAADLDNRFRKRTHSAGTSPTI-----THQKTPSQSSVASIEEYTEMMPAYPPGGGSGGR 567
            S +DLD+   +  +  G+S            +PS  S  S+E  ++       G   G  
Sbjct: 101  SPSDLDSLDGRSLNDDGSSDPRDIDQDNRSTSPSIYSPGSVENDSDSSS----GLSQGPA 156

Query: 568  LPGHRHSAFVP-------TRSYPEEGLEMHPLERRGGHHRP----DSSTLHTDDGYMPMS 616
             P H    F P       T   PE   E HP     G+H P     S       G  P  
Sbjct: 157  RPYHPPPLFPPSPQPPDSTPRQPEASFEPHPSVTPTGYHAPMEPPTSRMFQAPPGAPPPH 216

Query: 617  PGVAPVPSGRKGSGDYMPMSPKSVSAPQQIINPI--RRHPQRVDPNGYMMMSPSGGCSPD 674
            P + P  +G   SG   PM PK   A   +  P   ++HP    P   + +S SG     
Sbjct: 217  PQLYPGGTGGVLSGP--PMGPKGGGAASSVGGPNGGKQHPPPTTP---ISVSSSGA---- 267

Query: 675  IGGGPSSSSSSSNAVPSGTSYGKLWTNGVGGHHSHVLPHPKPPVESSGGKLLPCTGDYMN 734
              G P +   ++   P G   G L +     +  HV P+  PP           +   + 
Sbjct: 268  -SGAPPTKPPTT---PVGG--GNLPSAPPPANFPHVTPNLPPPPALRPLNNASASPPGLG 321

Query: 735  MSPVGDSNTSSPSDCYYG----PEDPQHKPVL--SYYSLPRSFKHTQRPGEPEEGARHQH 788
              P+   +  SP     G    P  P+  P L  S +SLP        P      A    
Sbjct: 322  AQPL-PGHLPSPHAMGQGMGGLPPGPEKGPTLAPSPHSLP--------PASSSAPAPPMR 372

Query: 789  LRLSTSSGRLLYAATADDSSSSTSSDSLGGGYCGARLEPSLPHPHHQVLQPHLPRKVDTA 848
               S+SS     +++A  SSSS+SS S    +  ++  PS PH                 
Sbjct: 373  FPYSSSS-----SSSAAASSSSSSSSSSASPFPASQALPSYPHS---------------- 411

Query: 849  AQTNSRLARPTRLSLGD-PKASTLPRAREQQQQQQPLLHPPEPKSPGEYVNIEFGSDQSG 907
                     PT LS+ + P   T P    Q    Q    PP P   G  +        S 
Sbjct: 412  ------FPPPTSLSVSNQPPKYTQPSLPSQAVWSQG---PPPPPPYGRLLA------NSN 456

Query: 908  YLSGPVAFHSSPSVRCPSQLQPAPREEETGTEEYMKMDLGPGRRAAWQESTGVEMGRLGP 967
               GP      PS    S   P      T    + +      ++   Q+      G  GP
Sbjct: 457  AHPGPFP----PSTGAQSTAHPPV---STHHHHHQQQQQQQQQQQQQQQQQQQHHGNSGP 509

Query: 968  APPGAASICRPTRAVPSSRGDYMTMQMSCPRQSYVDTSPAAPVSYADMRTGIAAEEVSLP 1027
             PPGA     P     S       M    P    +   P  P       + ++  +   P
Sbjct: 510  PPPGAFP--HPLEGGSSHHAHPYAMS---PSLGSLRPYPPGPAHLPPPHSQVSYSQAG-P 563

Query: 1028 RATMAAASSSSAASASPTGPQGAAELAAHSSLLGGPQGPGG---------------MSAF 1072
                 ++SS+S++S S    QG+    +H S   GPQG                   +  
Sbjct: 564  NGPPVSSSSNSSSSTS----QGSYP-CSHPSPSQGPQGAPYPFPPVPTVTTSSATLSTVI 618

Query: 1073 TRVNLSPNRNQSAKVIRADPQGCRRRHSSETFSSTPSATRVGNTVPFGAGAAVGGGGGSS 1132
              V  SP   ++A      P G R        ++TP   + G+   F  G   G  G S 
Sbjct: 619  ATVASSPAGYKTASPPGPPPYGKRAPSPGAYKTATPPGYKPGSPPSFRTGTPPGYRGTSP 678

Query: 1133 SSSEDVKRHSSASFENVWLRPGELGGAPKEPAKLCGAAGGLENGLNYIDLDLVKDFKQCP 1192
             +     +  S +     L P    G P  P      A G       I  +  +++ + P
Sbjct: 679  PAGPGTFKPGSPTVGPGPLPPAGPSGLPSLPPPPAAPASGPPLSATQIKQEPAEEY-ETP 737

Query: 1193 QECTPEPQPPPPPPPHQPLGSGESSSTR 1220
            +   P  + P PPP    + S  S S R
Sbjct: 738  ESPVPPARSPSPPPKVVDVPSHASQSAR 765



 Score = 45.1 bits (105), Expect = 4e-04
 Identities = 110/497 (22%), Positives = 169/497 (34%), Gaps = 87/497 (17%)

Query: 384 PSATSPVSLSSSSTSGHGSTSDCLFPRRSSASVSGSPSDGGFISSDEYGSSPCDFRSSFR 443
           P  T+P+S+SSS  SG   T               +P  GG + S      P +F     
Sbjct: 254 PPPTTPISVSSSGASGAPPTKP-----------PTTPVGGGNLPS---APPPANFPHVTP 299

Query: 444 SVTP-------DSLGHTPPARGEEELSNYI--------CMGG------KGPSTLTAPNGH 482
           ++ P       ++   +PP  G + L  ++         MGG      KGP+   AP+ H
Sbjct: 300 NLPPPPALRPLNNASASPPGLGAQPLPGHLPSPHAMGQGMGGLPPGPEKGPT--LAPSPH 357

Query: 483 YILSRGGNGHRCT---PGTGLGTSPALAGDEAASAADLDNRF------RKRTHSAGTSPT 533
            +     +        P +   +S A A   ++S++   + F          HS     +
Sbjct: 358 SLPPASSSAPAPPMRFPYSSSSSSSAAASSSSSSSSSSASPFPASQALPSYPHSFPPPTS 417

Query: 534 ITHQKTP---SQSSVASIEEYTEMMPAYPPGG-------GSGGRLP---GHRHSAFVPTR 580
           ++    P   +Q S+ S   +++  P  PP G          G  P   G + +A  P  
Sbjct: 418 LSVSNQPPKYTQPSLPSQAVWSQGPPPPPPYGRLLANSNAHPGPFPPSTGAQSTAHPPVS 477

Query: 581 SYPEEGLEMHPLERRGGHHRPDSSTLHTDDGYMPMSPGVAPVP--SGRKGSGDYMPMSPK 638
           ++     +    +++    +      H + G  P  PG  P P   G         MSP 
Sbjct: 478 THHHHHQQQQQQQQQQQQQQQQQQQHHGNSG--PPPPGAFPHPLEGGSSHHAHPYAMSPS 535

Query: 639 SVSAPQQIINPIRRHPQRVDPNGYMMMSPSGGCSPDIGGGPSSSSSSSNAVPSGTSYGKL 698
             S       P    P    P+  +  S +G       G P SSSS+S++  S  SY   
Sbjct: 536 LGSLRPYPPGPAHLPP----PHSQVSYSQAGP-----NGPPVSSSSNSSSSTSQGSYPCS 586

Query: 699 WTNGVGGHHSHVLPHPKPPVESSGGKLLPCTGDYMNMSPVGDSNTSSPSDCYYGPEDPQH 758
             +   G      P P  P  ++    L      +  SP G    S P    YG   P  
Sbjct: 587 HPSPSQGPQGAPYPFPPVPTVTTSSATLSTVIATVASSPAGYKTASPPGPPPYGKRAP-- 644

Query: 759 KPVLSYYSLPRSFKHTQRPGEPEEGARHQHLRLSTSSGRLLYAATADDSSSSTSSDSLGG 818
            P     + P  +K    PG P         R  T  G    +  A   +    S ++G 
Sbjct: 645 SPGAYKTATPPGYK----PGSPPS------FRTGTPPGYRGTSPPAGPGTFKPGSPTVGP 694

Query: 819 G---YCGARLEPSLPHP 832
           G     G    PSLP P
Sbjct: 695 GPLPPAGPSGLPSLPPP 711


>gi|55750041 atrophin-1 [Homo sapiens]
          Length = 1190

 Score = 65.9 bits (159), Expect = 2e-10
 Identities = 169/748 (22%), Positives = 244/748 (32%), Gaps = 123/748 (16%)

Query: 513  SAADLDNRFRKRTHSAGTSPTI-----THQKTPSQSSVASIEEYTEMMPAYPPGGGSGGR 567
            S +DLD+   +  +  G+S            +PS  S  S+E  ++       G   G  
Sbjct: 101  SPSDLDSLDGRSLNDDGSSDPRDIDQDNRSTSPSIYSPGSVENDSDSSS----GLSQGPA 156

Query: 568  LPGHRHSAFVP-------TRSYPEEGLEMHPLERRGGHHRP----DSSTLHTDDGYMPMS 616
             P H    F P       T   PE   E HP     G+H P     S       G  P  
Sbjct: 157  RPYHPPPLFPPSPQPPDSTPRQPEASFEPHPSVTPTGYHAPMEPPTSRMFQAPPGAPPPH 216

Query: 617  PGVAPVPSGRKGSGDYMPMSPKSVSAPQQIINPI--RRHPQRVDPNGYMMMSPSGGCSPD 674
            P + P  +G   SG   PM PK   A   +  P   ++HP    P   + +S SG     
Sbjct: 217  PQLYPGGTGGVLSGP--PMGPKGGGAASSVGGPNGGKQHPPPTTP---ISVSSSGA---- 267

Query: 675  IGGGPSSSSSSSNAVPSGTSYGKLWTNGVGGHHSHVLPHPKPPVESSGGKLLPCTGDYMN 734
              G P +   ++   P G   G L +     +  HV P+  PP           +   + 
Sbjct: 268  -SGAPPTKPPTT---PVGG--GNLPSAPPPANFPHVTPNLPPPPALRPLNNASASPPGLG 321

Query: 735  MSPVGDSNTSSPSDCYYG----PEDPQHKPVL--SYYSLPRSFKHTQRPGEPEEGARHQH 788
              P+   +  SP     G    P  P+  P L  S +SLP        P      A    
Sbjct: 322  AQPL-PGHLPSPHAMGQGMGGLPPGPEKGPTLAPSPHSLP--------PASSSAPAPPMR 372

Query: 789  LRLSTSSGRLLYAATADDSSSSTSSDSLGGGYCGARLEPSLPHPHHQVLQPHLPRKVDTA 848
               S+SS     +++A  SSSS+SS S    +  ++  PS PH                 
Sbjct: 373  FPYSSSS-----SSSAAASSSSSSSSSSASPFPASQALPSYPHS---------------- 411

Query: 849  AQTNSRLARPTRLSLGD-PKASTLPRAREQQQQQQPLLHPPEPKSPGEYVNIEFGSDQSG 907
                     PT LS+ + P   T P    Q    Q    PP P   G  +        S 
Sbjct: 412  ------FPPPTSLSVSNQPPKYTQPSLPSQAVWSQG---PPPPPPYGRLLA------NSN 456

Query: 908  YLSGPVAFHSSPSVRCPSQLQPAPREEETGTEEYMKMDLGPGRRAAWQESTGVEMGRLGP 967
               GP      PS    S   P      T    + +      ++   Q+      G  GP
Sbjct: 457  AHPGPFP----PSTGAQSTAHPPV---STHHHHHQQQQQQQQQQQQQQQQQQQHHGNSGP 509

Query: 968  APPGAASICRPTRAVPSSRGDYMTMQMSCPRQSYVDTSPAAPVSYADMRTGIAAEEVSLP 1027
             PPGA     P     S       M    P    +   P  P       + ++  +   P
Sbjct: 510  PPPGAFP--HPLEGGSSHHAHPYAMS---PSLGSLRPYPPGPAHLPPPHSQVSYSQAG-P 563

Query: 1028 RATMAAASSSSAASASPTGPQGAAELAAHSSLLGGPQGPGG---------------MSAF 1072
                 ++SS+S++S S    QG+    +H S   GPQG                   +  
Sbjct: 564  NGPPVSSSSNSSSSTS----QGSYP-CSHPSPSQGPQGAPYPFPPVPTVTTSSATLSTVI 618

Query: 1073 TRVNLSPNRNQSAKVIRADPQGCRRRHSSETFSSTPSATRVGNTVPFGAGAAVGGGGGSS 1132
              V  SP   ++A      P G R        ++TP   + G+   F  G   G  G S 
Sbjct: 619  ATVASSPAGYKTASPPGPPPYGKRAPSPGAYKTATPPGYKPGSPPSFRTGTPPGYRGTSP 678

Query: 1133 SSSEDVKRHSSASFENVWLRPGELGGAPKEPAKLCGAAGGLENGLNYIDLDLVKDFKQCP 1192
             +     +  S +     L P    G P  P      A G       I  +  +++ + P
Sbjct: 679  PAGPGTFKPGSPTVGPGPLPPAGPSGLPSLPPPPAAPASGPPLSATQIKQEPAEEY-ETP 737

Query: 1193 QECTPEPQPPPPPPPHQPLGSGESSSTR 1220
            +   P  + P PPP    + S  S S R
Sbjct: 738  ESPVPPARSPSPPPKVVDVPSHASQSAR 765



 Score = 45.1 bits (105), Expect = 4e-04
 Identities = 110/497 (22%), Positives = 169/497 (34%), Gaps = 87/497 (17%)

Query: 384 PSATSPVSLSSSSTSGHGSTSDCLFPRRSSASVSGSPSDGGFISSDEYGSSPCDFRSSFR 443
           P  T+P+S+SSS  SG   T               +P  GG + S      P +F     
Sbjct: 254 PPPTTPISVSSSGASGAPPTKP-----------PTTPVGGGNLPS---APPPANFPHVTP 299

Query: 444 SVTP-------DSLGHTPPARGEEELSNYI--------CMGG------KGPSTLTAPNGH 482
           ++ P       ++   +PP  G + L  ++         MGG      KGP+   AP+ H
Sbjct: 300 NLPPPPALRPLNNASASPPGLGAQPLPGHLPSPHAMGQGMGGLPPGPEKGPT--LAPSPH 357

Query: 483 YILSRGGNGHRCT---PGTGLGTSPALAGDEAASAADLDNRF------RKRTHSAGTSPT 533
            +     +        P +   +S A A   ++S++   + F          HS     +
Sbjct: 358 SLPPASSSAPAPPMRFPYSSSSSSSAAASSSSSSSSSSASPFPASQALPSYPHSFPPPTS 417

Query: 534 ITHQKTP---SQSSVASIEEYTEMMPAYPPGG-------GSGGRLP---GHRHSAFVPTR 580
           ++    P   +Q S+ S   +++  P  PP G          G  P   G + +A  P  
Sbjct: 418 LSVSNQPPKYTQPSLPSQAVWSQGPPPPPPYGRLLANSNAHPGPFPPSTGAQSTAHPPVS 477

Query: 581 SYPEEGLEMHPLERRGGHHRPDSSTLHTDDGYMPMSPGVAPVP--SGRKGSGDYMPMSPK 638
           ++     +    +++    +      H + G  P  PG  P P   G         MSP 
Sbjct: 478 THHHHHQQQQQQQQQQQQQQQQQQQHHGNSG--PPPPGAFPHPLEGGSSHHAHPYAMSPS 535

Query: 639 SVSAPQQIINPIRRHPQRVDPNGYMMMSPSGGCSPDIGGGPSSSSSSSNAVPSGTSYGKL 698
             S       P    P    P+  +  S +G       G P SSSS+S++  S  SY   
Sbjct: 536 LGSLRPYPPGPAHLPP----PHSQVSYSQAGP-----NGPPVSSSSNSSSSTSQGSYPCS 586

Query: 699 WTNGVGGHHSHVLPHPKPPVESSGGKLLPCTGDYMNMSPVGDSNTSSPSDCYYGPEDPQH 758
             +   G      P P  P  ++    L      +  SP G    S P    YG   P  
Sbjct: 587 HPSPSQGPQGAPYPFPPVPTVTTSSATLSTVIATVASSPAGYKTASPPGPPPYGKRAP-- 644

Query: 759 KPVLSYYSLPRSFKHTQRPGEPEEGARHQHLRLSTSSGRLLYAATADDSSSSTSSDSLGG 818
            P     + P  +K    PG P         R  T  G    +  A   +    S ++G 
Sbjct: 645 SPGAYKTATPPGYK----PGSPPS------FRTGTPPGYRGTSPPAGPGTFKPGSPTVGP 694

Query: 819 G---YCGARLEPSLPHP 832
           G     G    PSLP P
Sbjct: 695 GPLPPAGPSGLPSLPPP 711


>gi|239743293 PREDICTED: mucin 12 [Homo sapiens]
          Length = 5478

 Score = 60.5 bits (145), Expect = 1e-08
 Identities = 187/871 (21%), Positives = 287/871 (32%), Gaps = 115/871 (13%)

Query: 288  HLNNPPPSQVGLTRRSRTESITATSPASMVG-GKPGSFRVRASSDGEGTMSRPASVDGSP 346
            H +      + L  RS T  +   S  S +  G   +  +  S+   G   +  +   SP
Sbjct: 1997 HSSQDATGTIVLPARSTTSVLLGESTTSPISSGSMETTALPGSTTTPGLSEKSTTFHSSP 2056

Query: 347  VSPSTNRTHAHRHRGSARLHPPLNHSRSIPMPASRCSPSATSPVSLSSSSTSGH---GST 403
             SP+T  + A             +HSR      +    S T+P  LS  ST+ H   GST
Sbjct: 2057 RSPATTLSPASTTSSGVSEESTTSHSRPGSTHTTAFPDSTTTP-GLSRHSTTSHSSPGST 2115

Query: 404  SDCLFPRRSSASVSGSPSDGGFISSDEYGSSPCDFRSSFRSVTPDSLGHTPPARGEEELS 463
               L P  +S + SG PS     S    GS+  D   S  S T  S G        +E +
Sbjct: 2116 DTTLLP--ASTTTSG-PSQESTTSHSSPGST--DTALSPGSTTALSFG--------QEST 2162

Query: 464  NYICMGGKGPSTL----TAPNGHYILSRGGNGHRCTPGTGL----GTSPALAGDEAASAA 515
             +    G   +TL    T  +G    S   +    +P T L     TSP L G+  A   
Sbjct: 2163 TFHSSPGSTHTTLFPDSTTSSGIVEASTRVHSSTGSPRTTLSPASSTSPGLQGESTAF-- 2220

Query: 516  DLDNRFRKRTHSAGTSPTITHQKTPSQSSVASIEEYTEMMPAYPPGGGSGGRLPGHRHSA 575
                    +TH A T  T     +P  ++ A +EE T                  HR   
Sbjct: 2221 --------QTHPASTHTT----PSPPSTATAPVEESTTY----------------HRSPG 2252

Query: 576  FVPTRSYPEEGLEM-HPLERRGGHHRPDSSTLHTDDGYMPMSPGVAPVPSGRKGSGDYMP 634
              PT  +P       H  +    H  PD+S      G  P S        G   +    P
Sbjct: 2253 STPTTHFPASSTTSGHSEKSTIFHSSPDAS------GTTPSSAHSTTSGRGESTTSRISP 2306

Query: 635  MSPKSVSAPQQIINPIRRHPQRV----DPNGYMMMSPSGGCSPDIGGGPSSSSSSSNAVP 690
             S +  + P     P              +    +SP+   S  +G   ++S S   +  
Sbjct: 2307 GSTEITTLPGSTTTPGLSEASTTFYSSPRSPTTTLSPASMTSLGVGEESTTSRSQPGSTH 2366

Query: 691  SGTSYGKLWTNGVGGHHSHVLPHPKPPVESSGGKLLPCTGDYMNMSPVGDSNTSSPSDCY 750
            S  S     T G+    + V        E++     P T      S  G+  T+  S   
Sbjct: 2367 STVSPASTTTPGLSEESTTVYSSSPGSTETTVFPRTPTT------SVRGEEPTTFHS--- 2417

Query: 751  YGPEDPQHKPVLSYYSLPRSFKHTQRPGEPEEGARHQHLRLSTSSGRLLYAATADDSSSS 810
                    +P  ++ +L      T   G  EE         ST +G      TAD    S
Sbjct: 2418 --------RPASTHTTLFTEDSTTS--GLTEESTAFPGSPASTQTGLPATLTTADLGEES 2467

Query: 811  TSSDSLGGGYCGARLEPSLPHPHHQVLQPHLPRKVDTAAQTNSRLARPTRLSLGDPKAS- 869
            T+  S   G  G  L P+       V +    R   ++ +T +    PT  SL +   + 
Sbjct: 2468 TTFPS-SSGSTGTTLSPARSTTSGLVGESTPSRLSPSSTETTTLPGSPTTPSLSEKSTTF 2526

Query: 870  -TLPRAREQQQQQQPLLHPPEPKSPGEYVNIEFGSDQSGYLSGPVAFHSSPSV----RCP 924
             T PR+ +        L P    S G          Q G  +   AF  S +     R  
Sbjct: 2527 YTSPRSPD------ATLSPATTTSSGVSEESSTSHSQPG-STHTTAFPDSTTTPGLSRHS 2579

Query: 925  SQLQPAPREEETGTEEYMKMDLGPGRRAAWQEST-GVEMGRLGPAPPGAASICRPTRAVP 983
            +    +P   +T          GP + +    S+ G     L P    A S  + +    
Sbjct: 2580 TTSHSSPGSTDTTLLPASTTTSGPSQESTTSHSSPGSTDTALSPGSTTALSFGQESTTFH 2639

Query: 984  SSRGDYMTMQMSCPRQSYVDTSPAAPVSYADMRTGIAAEEVSLPRATMAAASSSSAASAS 1043
            SS G   T         + D++ ++ +  A  R          PR T++ ASS+S     
Sbjct: 2640 SSPGSTHT-------TLFPDSTTSSGIVEASTR---VHSSTGSPRTTLSPASSTSPGLQG 2689

Query: 1044 PTGPQGAAELAAHSSLLGGPQGPGGMSAFTRVNLSPNRNQSAKVIRADPQGCRRRHSSET 1103
             +        + H++    P  P   +A    + + +R+  +      P        SE 
Sbjct: 2690 ESTTFQTHPASTHTT----PSPPSTATAPVEESTTYHRSPGSTPTTHFPASSTTSGHSEK 2745

Query: 1104 FSSTPSATRVGNTVPFGAGAAVGGGGGSSSS 1134
             +   S+     T P  A +   G G S++S
Sbjct: 2746 STIFHSSPDASGTTPSSAHSTTSGRGESTTS 2776



 Score = 59.3 bits (142), Expect = 2e-08
 Identities = 200/929 (21%), Positives = 305/929 (32%), Gaps = 197/929 (21%)

Query: 298  GLTRRSRTESITATSPASMVGGKPGSFRVRASSDGEGTM-SRPASVDGSPVSPSTNRTHA 356
            GL+ RS T   +  SPA+ +   P S      S+   T  SRP S   +    ST     
Sbjct: 961  GLSERSTTFHSSPRSPATTLS--PASTTSSGVSEESTTSRSRPGSTHTTAFPDSTTTPGL 1018

Query: 357  HRHRGSARLHPPLNHSRSIPMPASRCSPSATSPVSLSSSSTSGHGSTSDCLFPRRSSASV 416
             RH  ++   P    +  +P   +   PS  S  S SSS     GST   L P  ++A  
Sbjct: 1019 SRHSTTSHSSPGSTDTTLLPASTTTSGPSQESTTSHSSS-----GSTDTALSPGSTTALS 1073

Query: 417  SGSPSDGGFISSDEYGSSPCDFRSSFRSVTPDSLGHTPPARGEEELSNYICMGGKGPSTL 476
             G         S  + S+P    S+  ++ PDS      + G  E S  +      P T 
Sbjct: 1074 FGQ-------ESTTFHSNP---GSTHTTLFPDS----TTSSGIVEASTRVHSSTGSPRTT 1119

Query: 477  TAPNGHYILSRGGNGHRCTPGTGLGTSPALAGDEAASAADLDNRFRKRTHSAGTSPTITH 536
             +P                      TSP L G+  A           +TH A T  T   
Sbjct: 1120 LSP-------------------ASSTSPGLQGESTAF----------QTHPASTHTT--- 1147

Query: 537  QKTPSQSSVASIEEYTEMMPAYPPGGGSGGRLPGHRHSAFVPTRSYPEEGLEMHPLERRG 596
              +P  ++ A +EE T           S G  P     A   T  + E+    H      
Sbjct: 1148 -PSPPSTATAPVEESTTY-------HRSPGSTPTTHFPASSTTSGHSEKSTIFHSSPDAS 1199

Query: 597  G----------HHRPDSSTLHTDDGYMPMS--PGVAPVPSGRKGSGDY--MPMSPKSVSA 642
            G            R +S+T     G   ++  PG    P   + S  +   P SP +  +
Sbjct: 1200 GTTPSSAHSTTSGRGESTTSRISPGSTEITTLPGSTTTPGLSEASTTFYSSPRSPTTTLS 1259

Query: 643  PQQIIN---PIRRHPQRVDPNG-YMMMSPSGGCSPDIGGGPSSSSSSSNAVPSGTSYGKL 698
            P  + +          R  P   +  +SP+   +P +    ++  SSS      T +   
Sbjct: 1260 PASMTSLGVGEESTTSRSQPGSTHSTVSPASTTTPGLSEESTTVYSSSRGSTETTVFPHS 1319

Query: 699  WTNGVGGHHS---HVLP-----------------------HPKPPVESSGGKLLPCTGDY 732
             T  V G      H  P                        P  P  +  G  LP T   
Sbjct: 1320 TTTSVHGEEPTTFHSRPASTHTTLFTEDSTTSGLTEESTAFPGSPASTQTG--LPAT--- 1374

Query: 733  MNMSPVGDSNTSSPSDCYYGPEDPQHKPVLSYYS-----------LPRSFKHTQRPGEPE 781
            +  + +G+ +T+ PS    G    +  P  S  S            P S + T  PG P 
Sbjct: 1375 LTTADLGEESTTFPSSS--GSTGTKLSPARSTTSGLVGESTPSRLSPSSTETTTLPGSPT 1432

Query: 782  EGARHQHLRLSTSSGRLLYAATADDSSSSTSSDSLGGGYCGARLEPSLPHPHHQVLQPHL 841
              +      LS  S     +  + D++ S ++ +  G    +    S P   H    P  
Sbjct: 1433 TPS------LSEKSTTFYTSPRSPDATLSPATTTSSGVSEESSTSHSQPGSTHTTAFPDS 1486

Query: 842  PRKVDTAAQT----NSRLARPTRLSLGDPKASTLPRAREQQQQQQPLLHPPEPKSPGEYV 897
                D + +     +S+ +    LS G   AS+L        QQ    H     SPG+  
Sbjct: 1487 TTTSDLSQEPTTSHSSQGSTEATLSPGSTTASSL-------GQQSTTFH----SSPGDTE 1535

Query: 898  NIEFGSD--QSGYLSGPVAFHSSP----SVRCPSQLQPAPREEETGTEEYMKMDLGPGRR 951
                  D   SG +      HSS     +   P+    A  +EE+ T +           
Sbjct: 1536 TTLLPDDTITSGLVEASTPTHSSTGSLHTTLTPASSTSAGLQEESTTFQ----------- 1584

Query: 952  AAWQESTGVEMGRLGPAPPGAASICRPTRAVPSSRGDYMTMQMSCPRQSYVDTSPAAPVS 1011
             +W  S+        P+PPG       T A P        +++S    S   ++P    S
Sbjct: 1585 -SWPSSSDTT-----PSPPG-------TTAAP--------VEVSTTYHSRPSSTPTTHFS 1623

Query: 1012 YADMRTGIAAEEV---SLPRATMAAASSSSAASASPTGPQGAAELAAHS---SLLGGPQG 1065
             +    G + E     S P AT  A   + +A++   G    + +++ S   + L G   
Sbjct: 1624 ASSTTLGRSEESTTVHSSPGATGTALFPTRSATSVLVGEPTTSPISSGSTETTALPGSTT 1683

Query: 1066 PGGMSAFTRVNLSPNRNQSAKVIRADPQGCRRRHSSETFSSTPSATRVGNTVPFGAGAAV 1125
              G+S  +    S  R+    +  A          S T  S P +T   +T  F     +
Sbjct: 1684 TAGLSEKSTTFYSSPRSPDTTLSPASTTSSGVSEESTTSHSRPGST---HTTAFPGSTTM 1740

Query: 1126 GGGGGSSSSSEDVKRHSSASFENVWLRPG 1154
             G      S E    HSS    +  L PG
Sbjct: 1741 PG-----VSQESTASHSSPGSTDTTLSPG 1764



 Score = 58.9 bits (141), Expect = 3e-08
 Identities = 186/857 (21%), Positives = 281/857 (32%), Gaps = 119/857 (13%)

Query: 288  HLNNPPPSQVGLTRRSRTESITATSPASMVG-GKPGSFRVRASSDGEGTMSRPASVDGSP 346
            H +      + L  RS T  +   S  S +  G   +  +  S+   G   +  +   SP
Sbjct: 3554 HSSQDATGTIVLPARSTTSVLLGESTTSPISSGSMETTALPGSTTTPGLSEKSTTFHSSP 3613

Query: 347  VSPSTNRTHAHRHRGSARLHPPLNHSRSIPMPASRCSPSATSPVSLSSSSTSGH---GST 403
             SP+T  + A             +HSR      +    S T+P  LS  ST+ H   GST
Sbjct: 3614 RSPATTLSPASTTSSGVSEESTTSHSRPGSTHTTAFPDSTTTP-GLSRHSTTSHSSPGST 3672

Query: 404  SDCLFPRRSSASVSGSPSDGGFISSDEYGSSPCDFRSSFRSVTPDSLGHTPPARGEEELS 463
               L P  +S + SGS  +           S     SS  + T  S G T      +E +
Sbjct: 3673 DTTLLP--ASTTTSGSSQE-----------STTSHSSSGSTDTALSPGSTTALSFGQEST 3719

Query: 464  NYICMGGKGPSTL----TAPNGHYILSRGGNGHRCTPGTGL----GTSPALAGDEAASAA 515
             +    G   +TL    T  +G    S   +    +P T L     TSP L G+  A   
Sbjct: 3720 TFHSSPGSTHTTLFPDSTTSSGIVEASTRVHSSTGSPRTTLSPASSTSPGLQGESTAF-- 3777

Query: 516  DLDNRFRKRTHSAGTSPTITHQKTPSQSSVASIEEYTEMMPAYPPGGGSGGRLPGHRHSA 575
                    +TH A T  T     +P  ++ A +EE T                  HR   
Sbjct: 3778 --------QTHPASTHTT----PSPPSTATAPVEESTTY----------------HRSPG 3809

Query: 576  FVPTRSYPEEGLEM-HPLERRGGHHRPDSSTLHTDDGYMPMSPGVAPVPSGRKGSGDYMP 634
              PT  +P       H  +    H  PD+S      G  P S        G   +    P
Sbjct: 3810 STPTTHFPASSTTSGHSEKSTIFHSSPDAS------GTTPSSAHSTTSGRGESTTSRISP 3863

Query: 635  MSPKSVSAPQQIINPIRRHPQRVDPNGYMMMSPSGGCSPDIGGGPSSSSSSSNAVPSGTS 694
             S +  + P          P   + +     SP    SP     P+S +S      S TS
Sbjct: 3864 GSTEITTLPGSTTT-----PGLSEASTTFYSSPR---SPTTTLSPASMTSLGVGEESTTS 3915

Query: 695  YGKLWTNGVGGHHSHVLPHPKPPVESSGGKLLPCTGDYMNMSPVGDSNTSSPSDCYYGPE 754
              +      G  HS V     P   ++ G     T  Y + SP     T  P        
Sbjct: 3916 RSQ-----PGSTHSTV----SPASTTTPGLSEESTTVY-SSSPGSTETTVFPRST---TT 3962

Query: 755  DPQHKPVLSYYSLPRSFKHT------QRPGEPEEGARHQHLRLSTSSGRLLYAATADDSS 808
              + +   +++S P S   T         G  EE         ST +G      TAD   
Sbjct: 3963 SVRREEPTTFHSRPASTHTTLFTEDSTTSGLTEESTAFPGSPASTQTGLPATLTTADLGE 4022

Query: 809  SSTSSDSLGGGYCGARLEPSLPHPHHQVLQPHLPRKVDTAAQTNSRLARPTRLSLGDPKA 868
             ST+  S   G  G +L P+       V +    R   ++ +T +    PT  SL +   
Sbjct: 4023 ESTTFPS-SSGSTGTKLSPARSTTSGLVGESTPSRLSPSSTETTTLPGSPTTPSLSEKST 4081

Query: 869  S--TLPRAREQQQQQQPLLHPPEPKSPGEYVNIEFGSDQSGYLSGPVAFHSSPSVRCPSQ 926
            +  T PR+ +        L P    S G          Q G  +   AF  S +    SQ
Sbjct: 4082 TFYTSPRSPD------ATLSPATTTSSGVSEESSTSHSQPG-STHTTAFPDSTTTSGLSQ 4134

Query: 927  LQPAPREEETGTEEYMKMDLGPGRRAAWQESTGVEMGRLGPAPPGAASICRPTRAVPSSR 986
             +P       G+ E     L PG   A   S G +      +P    +   P   + S  
Sbjct: 4135 -EPTTSHSSQGSTE---ATLSPGSTTA--SSLGQQSTTFHSSPGDTETTLLPDDTITSGL 4188

Query: 987  GDYMTMQMSCPRQSYVDTSPAAPVSYADMRTGIAAEEVSLPRATMAAASSSSAASASPTG 1046
             +  T   S     +   +PA+  S     TG+  E  +         S  S++  +P+ 
Sbjct: 4189 VEASTPTHSSTGSLHTTLTPASSTS-----TGLQEESTTF-------QSWPSSSDTTPSP 4236

Query: 1047 PQGAAELAAHSSLLGGPQGPGGMSAFTRVNLSPNRNQSAKVIRADPQGCRRRHSSETFSS 1106
            P   A     S+           + F+  + +  R++ +  + + P G        T S+
Sbjct: 4237 PSTTAVPVEVSTTYHSRPSSTPTTHFSASSTTLGRSEESTTVHSSP-GATGTALFPTRSA 4295

Query: 1107 TPSATRVGNTVPFGAGA 1123
            T        T P  +G+
Sbjct: 4296 TSVLVGEPTTSPISSGS 4312



 Score = 55.5 bits (132), Expect = 3e-07
 Identities = 200/900 (22%), Positives = 308/900 (34%), Gaps = 143/900 (15%)

Query: 300  TRRSRTESITAT--SPASMVGGKPGSFRVRASSDGEGTMSRPASVDGSPVSPSTNRTHAH 357
            T    TE  TA   SPAS   G P +       +   T    +   G+ +SP+ + T   
Sbjct: 2906 TTSGLTEESTAFPGSPASTQTGLPATLTTADLGEESTTFPSSSGSTGTTLSPARSTTSGL 2965

Query: 358  RHRGS-ARLHPPLNHSRSIPMPASRCSPSATSPVSLSSSSTSGHGSTSDCLFPRRSSASV 416
                + +RL P    + ++P        S T+P SLS  ST+ + S      PR   A++
Sbjct: 2966 VGESTPSRLSPSSTETTTLP-------GSPTTP-SLSEKSTTFYTS------PRSPDATL 3011

Query: 417  SGSPSDGGFISSDEYGSSPCDFRSSFRSVTPDSLGHTPPARGEEELSNYICMGGK----G 472
            S + +    +S +E  +S     S+  +  PDS   T     +E  +++   G       
Sbjct: 3012 SPATTTSSGVS-EESSTSHSQPGSTHTTAFPDST--TTSGLSQEPTASHSSQGSTEATLS 3068

Query: 473  PSTLTAPNGHYILSRGGNGHRCTPGTGLGTSPALAGDEAASAADLDNRFRKRTHSAGTSP 532
            P + TA +    L +       +PG    T   L  D+  ++  ++      THS+  S 
Sbjct: 3069 PGSTTASS----LGQQSTTFHSSPGD---TETTLLPDDTITSGLVEAS--TPTHSSTGSL 3119

Query: 533  TITHQKTPSQSSVASIEEYTEMMPAYPPGGGSGGRLPGHRHSAFVPTRSYPEEGLEMHPL 592
              T   TP+ S+ A ++E +    ++P    +    PG   +    + +Y        P 
Sbjct: 3120 HTT--LTPASSTSAGLQEESTTFQSWPSSSDTTPSPPGTTAAPVEVSTTY-----HSRPS 3172

Query: 593  ERRGGHHRPDSSTLHTDDGYMPMSPGVAPVPSGRKGSGDYMPMSPKSVSAPQQIINPIRR 652
                 H    S+TL    G    S  V   P G  G+  +   S  SV   +   +PI  
Sbjct: 3173 STPTTHFSASSTTL----GRSEESTTVHSSP-GATGTALFPTRSATSVLVGEPTTSPISS 3227

Query: 653  H-------PQRVDPNGYMMMSP---SGGCSPDIGGGPSSSSSSSNAVPSGTSYGKLWTNG 702
                    P      G    S    S   SPD    P+S++SS  +  S TS+ +     
Sbjct: 3228 GSTETTALPGSTTTAGLSEKSTTFYSSPRSPDTTLSPASTTSSGVSEESTTSHSR----- 3282

Query: 703  VGGHHSHVLPH----PKPPVESSGGKLLPCTGDYMNMSPVGDSNTSSPSDCYYGPEDPQH 758
             G  H+   P     P    ES+     P + D   +SP G +  SS      GPE    
Sbjct: 3283 PGSTHTTAFPGSTTMPGVSQESTASHSSPGSTD-TTLSP-GSTTASS-----LGPEST-- 3333

Query: 759  KPVLSYYSLPRSFKHTQRPGEPEEGARHQHLRLSTSSGRLLYAATADDSSSSTSSDSLGG 818
                +++S P S + T  P              +T+SG LL A+T   SS+ +   +L  
Sbjct: 3334 ----TFHSGPGSTETTLLPDN------------TTASG-LLEASTPVHSSTGSPHTTLSP 3376

Query: 819  GYCGARLEPSLPHPHHQVLQPHLPRKVDTAAQTNSRLARPTRLSLGDPKAS--------- 869
                 R   S          P+          T S     +  S G P ++         
Sbjct: 3377 AGSTTRQGESTTFQSW----PNSKDTTPAPPTTTSAFVELSTTSHGSPSSTPTTHFSASS 3432

Query: 870  -TLPRAREQQQQQQPLLHPPEPKSPGEYVNIEFGSDQSGYLSGPVAFHSSPSVRCPSQLQ 928
             TL R+ E        +      SP         S  SG +     +HSSP         
Sbjct: 3433 TTLGRSEESTTVHSSPVATATTPSPAR-------STTSGLVEESTTYHSSPG-------- 3477

Query: 929  PAPREEETGTEEYMKMDLGPGRRAAWQESTGVEMGRLGPAPPGAASICRPTRAVPSSRGD 988
                   T T  + + D   GR      S       +  AP   +++     +  SS G 
Sbjct: 3478 ------STQTMHFPESDTTSGRGEESTTSHSSTTHTISSAPSTTSALVEEPTSYHSSPGS 3531

Query: 989  YMTMQMSCPRQSYVDTSPAAPVSYADMRTGIAAEEVSLP-RATMAAASSSSAASASPTGP 1047
              T     P  S   TS  +  S A   +  A   + LP R+T +     S  S   +G 
Sbjct: 3532 TATTHF--PDSS--TTSGRSEESTASHSSQDATGTIVLPARSTTSVLLGESTTSPISSGS 3587

Query: 1048 QGAAELAAHSSLLGGPQGPGGMSAFTR---VNLSPNRNQSAKVIRADPQGCRRRHSSETF 1104
                 L   ++  G  +      +  R     LSP    S+ V         R  S+ T 
Sbjct: 3588 METTALPGSTTTPGLSEKSTTFHSSPRSPATTLSPASTTSSGVSEESTTSHSRPGSTHTT 3647

Query: 1105 S-----STPSATRVGNTVPFGAGAA-----VGGGGGSSSSSEDVKRHSSASFENVWLRPG 1154
            +     +TP  +R   T     G+            S SS E    HSS+   +  L PG
Sbjct: 3648 AFPDSTTTPGLSRHSTTSHSSPGSTDTTLLPASTTTSGSSQESTTSHSSSGSTDTALSPG 3707



 Score = 55.1 bits (131), Expect = 4e-07
 Identities = 187/864 (21%), Positives = 287/864 (33%), Gaps = 104/864 (12%)

Query: 294  PSQVGLTRRSRTESITAT-SPASM-VGGKPGSFRVRASSDGEGTMSRPASVDGSPVSPST 351
            PS    T   R ES T+  SP S  +   PGS      S+   T         SP SP+T
Sbjct: 2286 PSSAHSTTSGRGESTTSRISPGSTEITTLPGSTTTPGLSEASTTFY------SSPRSPTT 2339

Query: 352  NRTHAHRHRGSARLHPPLNHSRSIPMPA-SRCSPSATSPVSLSSSST----SGHGSTSDC 406
              + A     S  +      SRS P    S  SP++T+   LS  ST    S  GST   
Sbjct: 2340 TLSPASMT--SLGVGEESTTSRSQPGSTHSTVSPASTTTPGLSEESTTVYSSSPGSTETT 2397

Query: 407  LFPRRSSASVSGSPSDGGFISSDEYGSSPCDFRSSFRSVTPDSLGHTP--------PARG 458
            +FPR  + SV G            + S P    ++  +    + G T         PA  
Sbjct: 2398 VFPRTPTTSVRGE-------EPTTFHSRPASTHTTLFTEDSTTSGLTEESTAFPGSPAST 2450

Query: 459  EEELSNYICMGGKGPSTLTAPNGHYILSRGGNGHRCTPGTGLGTSPALAGDEAASAADLD 518
            +  L   +     G  + T P+     S G  G   +P     T+  L G+   S     
Sbjct: 2451 QTGLPATLTTADLGEESTTFPS-----SSGSTGTTLSPARS--TTSGLVGESTPSRLSPS 2503

Query: 519  NRFRKRTHSAGTSPTITHQKTPSQSSVASIEEYTEMMPAYPPGGG------SGGRLPGHR 572
            +        + T+P+++ + T   +S  S +    + PA     G      +    PG  
Sbjct: 2504 STETTTLPGSPTTPSLSEKSTTFYTSPRSPD--ATLSPATTTSSGVSEESSTSHSQPGST 2561

Query: 573  HSAFVPTRSYPEEGLEMHPLERRGGHHRPDSSTLHTDDGYMPMS-----PGVAPVPSGRK 627
            H+   P  S    GL  H       H  P S    TD   +P S     P      S   
Sbjct: 2562 HTTAFPD-STTTPGLSRHSTT---SHSSPGS----TDTTLLPASTTTSGPSQESTTSHSS 2613

Query: 628  GSGDYMPMSPKSVSAPQQIINPIRRHPQRVDPNGYMMMSPSGGCSPDIGGGPSSSSSSSN 687
                   +SP S +A          H      + +  + P    S  I    +   SS+ 
Sbjct: 2614 PGSTDTALSPGSTTALSFGQESTTFHSS--PGSTHTTLFPDSTTSSGIVEASTRVHSSTG 2671

Query: 688  AVPSGTSYGKLWTNGVGGHHSHVLPHPKPPVESSGGKLLPCTGDYMNMSPVGDSNTSSPS 747
            +  +  S     + G+ G  +    HP     +      P T      +PV +S T   S
Sbjct: 2672 SPRTTLSPASSTSPGLQGESTTFQTHPASTHTTPSP---PSTAT----APVEESTTYHRS 2724

Query: 748  DCYYGPEDPQHKPVLSYYSLPRSFKHTQRPGEPEEGARHQHLRLSTSSGRLLYAATADDS 807
                G     H P  S  S   S K T     P+          ST+SGR   + T+  S
Sbjct: 2725 P---GSTPTTHFPASSTTS-GHSEKSTIFHSSPDASGTTPSSAHSTTSGRG-ESTTSRIS 2779

Query: 808  SSSTSSDSLGGGYCGARLEP------SLPHPHHQVLQPHLPRKVDTAAQTNSRLARP-TR 860
              ST   +L G      L        S P      L P     +    ++ +  ++P + 
Sbjct: 2780 PGSTEITTLPGSTTTPGLSEASTTFYSSPRSPTTTLSPASMTSLGVGEESTTSRSQPGST 2839

Query: 861  LSLGDPKASTLPRAREQQQQQQPLLHPPEPKSPGEYVNIEFGSDQSGYLSG--PVAFHSS 918
             S   P ++T P   E+              SPG      F    +  + G  P  FHS 
Sbjct: 2840 HSTVSPASTTTPGLSEESTTVYS-------SSPGSTETTVFPRSTTTSVRGEEPTTFHSR 2892

Query: 919  PSVRCPSQLQPAPREEETGTEEYMKMDLGPGRRAAWQES-----TGVEMGRLGPAPPGAA 973
            P+    S       E+ T +    +    PG  A+ Q       T  ++G      P ++
Sbjct: 2893 PA----STHTTLFTEDSTTSGLTEESTAFPGSPASTQTGLPATLTTADLGEESTTFPSSS 2948

Query: 974  ----SICRPTRAVPSSRGDYMTMQMSCPRQSYVDTSPAAPV--SYADMRTGIAAEEVSLP 1027
                +   P R+  S      T     P  +   T P +P   S ++  T       S P
Sbjct: 2949 GSTGTTLSPARSTTSGLVGESTPSRLSPSSTETTTLPGSPTTPSLSEKSTTFYTSPRS-P 3007

Query: 1028 RATMAAASSSSAASASPTGPQGAAELAAHSSLLGGPQGPGGMSAFTRVNLSPNRNQSAKV 1087
             AT++ A+++S+  +  +    +   + H++         G+S     + S   +  A +
Sbjct: 3008 DATLSPATTTSSGVSEESSTSHSQPGSTHTTAFPDSTTTSGLSQEPTASHSSQGSTEATL 3067

Query: 1088 IRADPQGCRRRHSSETFSSTPSAT 1111
                         S TF S+P  T
Sbjct: 3068 SPGSTTASSLGQQSTTFHSSPGDT 3091



 Score = 53.9 bits (128), Expect = 9e-07
 Identities = 199/912 (21%), Positives = 315/912 (34%), Gaps = 145/912 (15%)

Query: 300  TRRSRTESITAT--SPASMVGGKPGSFRVRASSDGEGTMSRPASVDGSPVSPSTNRTHAH 357
            T    TE  TA   SPAS   G P +       +   T    +   G+ +SP+ + T   
Sbjct: 1349 TTSGLTEESTAFPGSPASTQTGLPATLTTADLGEESTTFPSSSGSTGTKLSPARSTTSGL 1408

Query: 358  RHRGS-ARLHPPLNHSRSIPMPASRCSPSATSPVSLSSSSTSGHGSTSDCLFPRRSSASV 416
                + +RL P    + ++P        S T+P SLS  ST+ + S      PR   A++
Sbjct: 1409 VGESTPSRLSPSSTETTTLP-------GSPTTP-SLSEKSTTFYTS------PRSPDATL 1454

Query: 417  SGSPSDGGFISSDEYGSSPCDFRSSFRSVTPDSLGHTPPARGEEELSNYICMGGK----G 472
            S + +    +S +E  +S     S+  +  PDS   T     +E  +++   G       
Sbjct: 1455 SPATTTSSGVS-EESSTSHSQPGSTHTTAFPDST--TTSDLSQEPTTSHSSQGSTEATLS 1511

Query: 473  PSTLTAPNGHYILSRGGNGHRCTPGTGLGTSPALAGDEAASAADLDNRFRKRTHSAGTSP 532
            P + TA +    L +       +PG    T   L  D+  ++  ++      THS+  S 
Sbjct: 1512 PGSTTASS----LGQQSTTFHSSPGD---TETTLLPDDTITSGLVEAS--TPTHSSTGSL 1562

Query: 533  TITHQKTPSQSSVASIEEYTEMMPAYPPGGGSGGRLPGHRHSAFVPTRSYPEEGLEMHPL 592
              T   TP+ S+ A ++E +    ++P    +    PG   +    + +Y        P 
Sbjct: 1563 HTT--LTPASSTSAGLQEESTTFQSWPSSSDTTPSPPGTTAAPVEVSTTY-----HSRPS 1615

Query: 593  ERRGGHHRPDSSTLHTDDGYMPMSPGVAPVPSGRKGSGDYMPMSPKSVSAPQQIINPIRR 652
                 H    S+TL    G    S  V   P G  G+  +   S  SV   +   +PI  
Sbjct: 1616 STPTTHFSASSTTL----GRSEESTTVHSSP-GATGTALFPTRSATSVLVGEPTTSPISS 1670

Query: 653  H-------PQRVDPNGYMMMSP---SGGCSPDIGGGPSSSSSSSNAVPSGTSYGKLWTNG 702
                    P      G    S    S   SPD    P+S++SS  +  S TS+ +     
Sbjct: 1671 GSTETTALPGSTTTAGLSEKSTTFYSSPRSPDTTLSPASTTSSGVSEESTTSHSR----- 1725

Query: 703  VGGHHSHVLP----HPKPPVESSGGKLLPCTGDYMNMSPVGDSNTSSPSDCYYGPEDPQH 758
             G  H+   P     P    ES+     P + D   +SP G +  SS      GPE    
Sbjct: 1726 PGSTHTTAFPGSTTMPGVSQESTASHSSPGSTD-TTLSP-GSTTASS-----LGPES--- 1775

Query: 759  KPVLSYYSLPRSFKHTQRPGEPEEGARHQHLRLSTSSGRLLYAATADDSSSSTSSDSLGG 818
                +++S P S + T  P              +T++  LL A+T   SS+ +   +L  
Sbjct: 1776 ---TTFHSSPGSTETTLLPD-------------NTTASGLLEASTPVHSSTGSPHTTLSP 1819

Query: 819  GYCGARLEPSLPHPHHQVLQPHLPRKVDTAAQTNSRLARPTRLSLGDP----------KA 868
                 R   S         +  +P        T S     +  S G P           +
Sbjct: 1820 AGSTTRQGESTTFQSWPSSKDTMP----APPTTTSAFVELSTTSHGSPSSTPTTHFSASS 1875

Query: 869  STLPRAREQQQQQQPLLHPPEPKSPGEYVNIEFGSDQSGYLSGPVAFHSSPSVRCPSQLQ 928
            +TL R+ E        +      SP         S  SG +    A+HSSP         
Sbjct: 1876 TTLGRSEESTTVHSSPVATATTPSPAR-------STTSGLVEESTAYHSSPG-------- 1920

Query: 929  PAPREEETGTEEYMKMDLGPGRRAAWQESTGVEMGRLGPAPPGAASICRPTRAVPSSRGD 988
                   T T  + +     GR    + S       +   P   +++     +  SS G 
Sbjct: 1921 ------STQTMHFPESSTASGRSEESRTSHSSTTHTISSPPSTTSALVEEPTSYHSSPGS 1974

Query: 989  YMTMQMSCPRQSYVDTSPAAPVSYADMRTGIAAEEVSLPRATMAAASSSSAASASPTGPQ 1048
              T     P  S   TS  +  S A   +  A   + LP    A +++S     S T P 
Sbjct: 1975 TATTHF--PDSS--TTSGRSEESTASHSSQDATGTIVLP----ARSTTSVLLGESTTSPI 2026

Query: 1049 GAAELAAHSSLLGGPQGPGGMSAFTRVNLSPNRNQSAKVIRADPQGCRRRHSSETFSSTP 1108
             +  +   ++L G    PG     T  + SP R+ +  +  A          S T  S P
Sbjct: 2027 SSGSMET-TALPGSTTTPGLSEKSTTFHSSP-RSPATTLSPASTTSSGVSEESTTSHSRP 2084

Query: 1109 SATRVGNTVPFGAGAAVGGGGGSSSSSEDVKRHSSASFENVWLRPGE--LGGAPKEPAKL 1166
             +T   +T  F       G    S++S     HSS    +  L P      G  +E    
Sbjct: 2085 GST---HTTAFPDSTTTPGLSRHSTTS-----HSSPGSTDTTLLPASTTTSGPSQESTTS 2136

Query: 1167 CGAAGGLENGLN 1178
              + G  +  L+
Sbjct: 2137 HSSPGSTDTALS 2148



 Score = 52.4 bits (124), Expect = 3e-06
 Identities = 195/900 (21%), Positives = 314/900 (34%), Gaps = 156/900 (17%)

Query: 300  TRRSRTESITAT--SPASMVGGKPGSFRVRASSDGEGTMSRPASVDGSPVSPSTNRTHAH 357
            T    TE  TA   SPAS   G P +       +   T    +   G+ +SP+ + T   
Sbjct: 3989 TTSGLTEESTAFPGSPASTQTGLPATLTTADLGEESTTFPSSSGSTGTKLSPARSTTSGL 4048

Query: 358  RHRGS-ARLHPPLNHSRSIPMPASRCSPSATSPVSLSSSSTSGHGSTSDCLFPRRSSASV 416
                + +RL P    + ++P        S T+P SLS  ST+ + S      PR   A++
Sbjct: 4049 VGESTPSRLSPSSTETTTLP-------GSPTTP-SLSEKSTTFYTS------PRSPDATL 4094

Query: 417  SGSPSDGGFISSDEYGSSPCDFRSSFRSVTPDSLGHTPPARGEEELSNYICMGGK----G 472
            S + +    +S +E  +S     S+  +  PDS   T     +E  +++   G       
Sbjct: 4095 SPATTTSSGVS-EESSTSHSQPGSTHTTAFPDST--TTSGLSQEPTTSHSSQGSTEATLS 4151

Query: 473  PSTLTAPNGHYILSRGGNGHRCTPGTGLGTSPALAGDEAASAADLDNRFRKRTHSAGTSP 532
            P + TA +    L +       +PG    T   L  D+  ++  ++      THS+  S 
Sbjct: 4152 PGSTTASS----LGQQSTTFHSSPGD---TETTLLPDDTITSGLVEAS--TPTHSSTGSL 4202

Query: 533  TITHQKTPSQSSVASIEEYTEMMPAYPPGGGSGGRLPGHRHSAFVPTRSYPEEGLEMHPL 592
              T   TP+ S+   ++E +    ++P    S    P    +  VP            P 
Sbjct: 4203 HTT--LTPASSTSTGLQEESTTFQSWP---SSSDTTPSPPSTTAVPVEV--STTYHSRPS 4255

Query: 593  ERRGGHHRPDSSTLHTDDGYMPMSPGVAPVPSGRKGSGDYMPMSPKSVSAPQQIINPIRR 652
                 H    S+TL    G    S  V   P G  G+  +   S  SV   +   +PI  
Sbjct: 4256 STPTTHFSASSTTL----GRSEESTTVHSSP-GATGTALFPTRSATSVLVGEPTTSPISS 4310

Query: 653  H-------PQRVDPNGYMMMSP---SGGCSPDIGGGPSSSSSSSNAVPSGTSYGKLWTNG 702
                    P      G    S    S   SPD    P+S++SS  +  S TS+ +     
Sbjct: 4311 GSTETTALPGSTTTAGLSEKSTTFYSSPRSPDTTLSPASTTSSGVSEESTTSHSR----- 4365

Query: 703  VGGHHSHVLPH----PKPPVESSGGKLLPCTGDYMNMSPVGDSNTSSPSDCYYGPEDPQH 758
             G  H+   P     P    ES+     P + D   +SP G +  SS      GPE    
Sbjct: 4366 PGSMHTTAFPSSTTMPGVSQESTASHSSPGSTD-TTLSP-GSTTASS-----LGPEST-- 4416

Query: 759  KPVLSYYSLPRSFKHTQRPGEPEEGARHQHLRLSTSSGRLLYAATADDSSSSTSSDSLGG 818
                +++S P S + T  P              +T+SG LL A+T   SS+ +   +L  
Sbjct: 4417 ----TFHSSPGSTETTLLPDN------------TTASG-LLEASTPVHSSTGSPHTTLSP 4459

Query: 819  GYCGARLEPSLPHPHHQVLQPHLPRKVDTAAQTNSRLARPTRLSLGDPKAS--------- 869
                 R   S          P+          T S     +  S G P ++         
Sbjct: 4460 AGSTTRQGESTTFQSW----PNSKDTTPAPPTTTSAFVELSTTSHGSPSSTPTTHFSASS 4515

Query: 870  -TLPRAREQQQQQQPLLHPPEPKSPGEYVNIEFGSDQSGYLSGPVAFHSSP----SVRCP 924
             TL R+ E        +      SP         S  SG +     +HSSP    ++  P
Sbjct: 4516 TTLGRSEESTTVHSSPVATATTPSPAR-------STTSGLVEESTTYHSSPGSTQTMHFP 4568

Query: 925  SQLQPAPREEETGTEEYMK---MDLGPGRRAAWQESTGVEMGRLGPAPPGAASICRPTRA 981
                 + R EE+ T        +   P   +A  E    E      +P   A+   P  +
Sbjct: 4569 ESNTTSGRGEESTTSHSSTTHTISSAPSTTSALVE----EPTSYHSSPGSTATTHFPDSS 4624

Query: 982  VPSSRGDYMTMQMSC---------PRQSYVDT----SPAAPVSYADMRTGIAAEEVSLPR 1028
              S R +  T   S          P +S        S  +P+S   M T       + P 
Sbjct: 4625 TTSGRSEESTASHSSQDATGTIVLPARSTTSVLLGESTTSPISSGSMETTALPGSTTTPG 4684

Query: 1029 ATMAAASSSSAASASPTGPQGAAELAAHSSLLGGPQGPGGMSA---FTRVNLSPNRNQSA 1085
             +  + +  S+ S++PT        +A S+ LG  +    + +    T    SP R+ ++
Sbjct: 4685 LSEKSTTFHSSPSSTPT-----THFSASSTTLGRSEESTTVHSSPVATATTPSPARSTTS 4739

Query: 1086 KVIRADPQGCRRRHSSETFSSTPSATRVGNTVPFGAGAAVGGGGGSSSSSEDVKRHSSAS 1145
             ++            S  + S+P +T+   T+ F   +   G    S +S     H+ +S
Sbjct: 4740 GLV----------EESTAYHSSPGSTQ---TMHFPESSTASGRSEESRTSHSSTTHTISS 4786



 Score = 50.4 bits (119), Expect = 1e-05
 Identities = 186/860 (21%), Positives = 294/860 (34%), Gaps = 134/860 (15%)

Query: 294  PSQVGLTRRSRTESI-TATSPASMVG-----------GKPGSFRVRASSDGEGTM----- 336
            PSQ   T  S   S  TA SP S                PGS       D   +      
Sbjct: 2129 PSQESTTSHSSPGSTDTALSPGSTTALSFGQESTTFHSSPGSTHTTLFPDSTTSSGIVEA 2188

Query: 337  -SRPASVDGSP---VSPSTNRTHAHRHRGSA-RLHPPLNHSRSIPMPASRCSPSATSPVS 391
             +R  S  GSP   +SP+++ +   +   +A + HP   H+   P P S    +AT+PV 
Sbjct: 2189 STRVHSSTGSPRTTLSPASSTSPGLQGESTAFQTHPASTHTT--PSPPS----TATAPVE 2242

Query: 392  LSSSSTSGHGSTSDCLFPRRSSASVSGSPSDGGFISSDEYGSSPCDFRSSFRSVTPDSLG 451
             S++     GST    FP  S+ S       G    S  + SSP          TP S  
Sbjct: 2243 ESTTYHRSPGSTPTTHFPASSTTS-------GHSEKSTIFHSSP-----DASGTTPSSAH 2290

Query: 452  HTPPARGEEELSNYICMGGKGPSTLTAPNGHYILSRGGNGHRCTPG-----TGLGTSPAL 506
             T   RGE   S  I  G    +TL              G   TPG     T   +SP  
Sbjct: 2291 STTSGRGESTTSR-ISPGSTEITTLP-------------GSTTTPGLSEASTTFYSSPRS 2336

Query: 507  AGDEAASAADLDNRFRKRTHSAGTSPTITHQK-TPSQSSVASIEEYTEMMPAYPPGGGSG 565
                 + A+       + + ++ + P  TH   +P+ ++   + E +  + +  PG    
Sbjct: 2337 PTTTLSPASMTSLGVGEESTTSRSQPGSTHSTVSPASTTTPGLSEESTTVYSSSPGSTET 2396

Query: 566  GRLPGHRHSAFVPTRSYPEEGLEMHPLERRGGHHRPDS--STLHTDDGYMPMSPGVAPVP 623
               P        PT S   E       E    H RP S  +TL T+D             
Sbjct: 2397 TVFPR------TPTTSVRGE-------EPTTFHSRPASTHTTLFTEDS----------TT 2433

Query: 624  SGRKGSGDYMPMSPKSVSA--PQQIINPIRRHPQRVDPNGY----MMMSPSGGCSPDIGG 677
            SG        P SP S     P  +            P+        +SP+   +  + G
Sbjct: 2434 SGLTEESTAFPGSPASTQTGLPATLTTADLGEESTTFPSSSGSTGTTLSPARSTTSGLVG 2493

Query: 678  GPSSSSSSSNAVPSGTSYGKLWTNGVGGHHSHVLPHPKPPVESSGGKLLPCTGDYMNMSP 737
              + S  S ++  + T  G   T  +    +     P+ P       L P T     +S 
Sbjct: 2494 ESTPSRLSPSSTETTTLPGSPTTPSLSEKSTTFYTSPRSP----DATLSPATTTSSGVSE 2549

Query: 738  VGDSNTSSPSDCYYGP-EDPQHKPVLSYYSLPRSFKHTQRPGEPEEGARHQHLRLSTSSG 796
               ++ S P   +     D    P LS +S   +  H+  PG  +       L  ST++ 
Sbjct: 2550 ESSTSHSQPGSTHTTAFPDSTTTPGLSRHS---TTSHSS-PGSTDTTL----LPASTTTS 2601

Query: 797  RLLYAATADDSSSSTSSDSLGGGYCGARLEPSLPHPHHQVLQPHLPRKVDTAAQTNSRLA 856
                 +T   SS  ++  +L  G   A          H            +   T++ L 
Sbjct: 2602 GPSQESTTSHSSPGSTDTALSPGSTTALSFGQESTTFH-----------SSPGSTHTTLF 2650

Query: 857  RPTRLSLGDPKASTLPRAREQQQQQQPLLHPPEPKSPGEYVNIEFGSDQSGYLSGPVAFH 916
              +  S G  +AST  R        +  L P    SPG         + + + + P + H
Sbjct: 2651 PDSTTSSGIVEAST--RVHSSTGSPRTTLSPASSTSPG------LQGESTTFQTHPASTH 2702

Query: 917  SSPSVRCPSQLQPAPREEETGTEEYMKMDLGPGRRAAWQESTGVEMGRLGPAPPGAASIC 976
            ++PS   P     AP EE T               A+   S   E   +  + P A+   
Sbjct: 2703 TTPS---PPSTATAPVEESTTYHRSPGSTPTTHFPASSTTSGHSEKSTIFHSSPDASGTT 2759

Query: 977  -RPTRAVPSSRGDYMTMQMSCPRQSYVDTSPAAPVS--YADMRTGIAAEEVSLPRATMAA 1033
                 +  S RG+  T ++S P  + + T P +  +   ++  T   +   S P  T++ 
Sbjct: 2760 PSSAHSTTSGRGESTTSRIS-PGSTEITTLPGSTTTPGLSEASTTFYSSPRS-PTTTLSP 2817

Query: 1034 ASSSSAASASPTGPQGAAELAAHSSLLGGPQGPGGMS--AFTRVNLSPNRNQSAKVIRAD 1091
            AS +S      +    +   + HS++        G+S  + T  + SP   ++    R+ 
Sbjct: 2818 ASMTSLGVGEESTTSRSQPGSTHSTVSPASTTTPGLSEESTTVYSSSPGSTETTVFPRST 2877

Query: 1092 PQGCRRRHSSETFSSTPSAT 1111
                R    + TF S P++T
Sbjct: 2878 TTSVRGEEPT-TFHSRPAST 2896



 Score = 48.5 bits (114), Expect = 4e-05
 Identities = 183/860 (21%), Positives = 272/860 (31%), Gaps = 163/860 (18%)

Query: 305  TESITATSPASMVGGKPGSF---RVRASSDGEGTMSRPASVDGSPVSPST-----NRTHA 356
            T +     P++   G P S     + A S   G +    +   SP S  T     + T +
Sbjct: 792  TTTSAFVEPSTTSHGSPSSIPTTHISARSTTSGLVEESTTYHSSPGSTQTMHFPESDTTS 851

Query: 357  HRHRGSARLHPPLNHSRSIPMPASRCSPSATSP-VSLSSSSTSGHGSTSDCLFPRRSSAS 415
             R   S   H    H+ S        +PS TS  V   +S  S  GST+   FP  S+ S
Sbjct: 852  GRGEESTTSHSSTTHTIS-------SAPSTTSALVEEPTSYHSSPGSTATTHFPDSSTTS 904

Query: 416  VSGSPSDGGFISSDEYGSSPCDFRSSFRSVTPDSLGHTPPARGEEELSNYICMGGKGPST 475
                 S     S D  G+     RS+  SV       +P + G  E +         P +
Sbjct: 905  GRSEESTASHSSQDATGTIVLPARST-TSVLLGESTTSPISSGSMETTAL-------PGS 956

Query: 476  LTAPNGHYILSRGGNGHRCTPGTGLGTSPALAGDEAASAADLDNRFRK-RTHSAG----- 529
             T P    +  R    H          SPA       S     +R R   TH+       
Sbjct: 957  TTTPG---LSERSTTFHSSPRSPATTLSPASTTSSGVSEESTTSRSRPGSTHTTAFPDST 1013

Query: 530  TSPTITHQKTPSQSSVASIEEYTEMMPA-YPPGGGSGGRLPGHRHSAFVPTR-------- 580
            T+P ++   T S SS  S +  T ++PA     G S      H  S    T         
Sbjct: 1014 TTPGLSRHSTTSHSSPGSTD--TTLLPASTTTSGPSQESTTSHSSSGSTDTALSPGSTTA 1071

Query: 581  -SYPEEGLEMHPLERRGGHHR---PDSST----------LHTDDG--YMPMSPGVAPVPS 624
             S+ +E    H     G  H    PDS+T          +H+  G     +SP  +  P 
Sbjct: 1072 LSFGQESTTFH--SNPGSTHTTLFPDSTTSSGIVEASTRVHSSTGSPRTTLSPASSTSP- 1128

Query: 625  GRKG----------SGDYMPMSPKSVSAPQQIINPIRRHPQRVDPNGYMMMSPSGG---- 670
            G +G          S    P  P + +AP +      R P       +   S + G    
Sbjct: 1129 GLQGESTAFQTHPASTHTTPSPPSTATAPVEESTTYHRSPGSTPTTHFPASSTTSGHSEK 1188

Query: 671  -----CSPDIGGGPSSS----------SSSSNAVPSGTSY----GKLWTNGVGGHHSHVL 711
                  SPD  G   SS          S++S   P  T      G   T G+    +   
Sbjct: 1189 STIFHSSPDASGTTPSSAHSTTSGRGESTTSRISPGSTEITTLPGSTTTPGLSEASTTFY 1248

Query: 712  PHPKPPVESSGGKLLPCTG-----------DYMNMSPVGDSNTSSP-----SDCYYGPED 755
              P+ P  +     +   G                S V  ++T++P     S   Y    
Sbjct: 1249 SSPRSPTTTLSPASMTSLGVGEESTTSRSQPGSTHSTVSPASTTTPGLSEESTTVYSSSR 1308

Query: 756  PQHKPVL---------------SYYSLPRSFKHT------QRPGEPEEGARHQHLRLSTS 794
               +  +               +++S P S   T         G  EE         ST 
Sbjct: 1309 GSTETTVFPHSTTTSVHGEEPTTFHSRPASTHTTLFTEDSTTSGLTEESTAFPGSPASTQ 1368

Query: 795  SGRLLYAATADDSSSSTSSDSLGGGYCGARLEPSLPHPHHQVLQPHLPRKVDTAAQTNSR 854
            +G      TAD    ST+  S   G  G +L P+       V +    R   ++ +T + 
Sbjct: 1369 TGLPATLTTADLGEESTTFPS-SSGSTGTKLSPARSTTSGLVGESTPSRLSPSSTETTTL 1427

Query: 855  LARPTRLSLGDPKAS--TLPRAREQQQQQQPLLHPPEPKSPGEYVNIEFGSDQSGYLSGP 912
               PT  SL +   +  T PR+            P    SP    +     + S   S P
Sbjct: 1428 PGSPTTPSLSEKSTTFYTSPRS------------PDATLSPATTTSSGVSEESSTSHSQP 1475

Query: 913  VAFHSS--PSVRCPSQLQPAPREEETGTEEYMKMDLGPGRRAAWQESTGVEMGRLGPAPP 970
             + H++  P     S L   P    + ++   +  L PG   A   S G +      +P 
Sbjct: 1476 GSTHTTAFPDSTTTSDLSQEPTTSHS-SQGSTEATLSPGSTTA--SSLGQQSTTFHSSPG 1532

Query: 971  GAASICRPTRAVPSSRGDYMTMQMSCPRQSYVDTSPAAPVSYADMRTGIAAEEVSLPRAT 1030
               +   P   + S   +  T   S     +   +PA+  S      G+  E       T
Sbjct: 1533 DTETTLLPDDTITSGLVEASTPTHSSTGSLHTTLTPASSTS-----AGLQEES-----TT 1582

Query: 1031 MAAASSSSAASASPTGPQGA 1050
              +  SSS  + SP G   A
Sbjct: 1583 FQSWPSSSDTTPSPPGTTAA 1602



 Score = 45.8 bits (107), Expect = 3e-04
 Identities = 183/882 (20%), Positives = 290/882 (32%), Gaps = 104/882 (11%)

Query: 290  NNPPPSQVGLTRRSRTES--ITATSPASMVGGKPGSFRVRASS---DGEGT--MSRPASV 342
            ++P  ++  L   + T S  + A++P     G P +    A S    GE T   S P+S 
Sbjct: 1780 SSPGSTETTLLPDNTTASGLLEASTPVHSSTGSPHTTLSPAGSTTRQGESTTFQSWPSSK 1839

Query: 343  DGSPVSPSTNRTHAH---RHRGSARLHPPLNHSRSIPM----------------PASRCS 383
            D  P  P+T            GS    P  + S S                    A+  S
Sbjct: 1840 DTMPAPPTTTSAFVELSTTSHGSPSSTPTTHFSASSTTLGRSEESTTVHSSPVATATTPS 1899

Query: 384  PSATSPVSLSSSSTSGH---GSTSDCLFPRRSSASVSGSPSDGGFISSDEYGSSPCDFRS 440
            P+ ++   L   ST+ H   GST    FP  S+AS     S     S+    SSP    S
Sbjct: 1900 PARSTTSGLVEESTAYHSSPGSTQTMHFPESSTASGRSEESRTSHSSTTHTISSPPSTTS 1959

Query: 441  SFRSVTPDSLGHTPPARGEEELSNYICMGGKGPSTLTAPNGHYILSRGGNGHRCTPGTGL 500
            +     P S   +P +       +     G+   +  + +     S+   G    P    
Sbjct: 1960 ALVE-EPTSYHSSPGSTATTHFPDSSTTSGRSEESTASHS-----SQDATGTIVLPAR-- 2011

Query: 501  GTSPALAGDEAASAADLDNRFRKRTHSAGTSPTITHQKTPSQSSVASIEEYTEMMPAYPP 560
             T+  L G+   S     +        + T+P ++ + T   SS  S    T + PA   
Sbjct: 2012 STTSVLLGESTTSPISSGSMETTALPGSTTTPGLSEKSTTFHSSPRS--PATTLSPASTT 2069

Query: 561  GGG------SGGRLPGHRHSAFVPTRSYPEEGLEMHPLERRGGHHRPDSSTLHTDDGYMP 614
              G      +    PG  H+   P  S    GL  H       H  P S    TD   +P
Sbjct: 2070 SSGVSEESTTSHSRPGSTHTTAFPD-STTTPGLSRHSTT---SHSSPGS----TDTTLLP 2121

Query: 615  MS-----PGVAPVPSGRKGSGDYMPMSPKSVSAPQQIINPIRRHPQRVDPNGYMMMSPSG 669
             S     P      S          +SP S +A          H      + +  + P  
Sbjct: 2122 ASTTTSGPSQESTTSHSSPGSTDTALSPGSTTALSFGQESTTFHSS--PGSTHTTLFPDS 2179

Query: 670  GCSPDIGGGPSSSSSSSNAVPSGTSYGKLWTNGVGGHHSHVLPHPKPPVESSGGKLLPCT 729
              S  I    +   SS+ +  +  S     + G+ G  +    HP     +      P T
Sbjct: 2180 TTSSGIVEASTRVHSSTGSPRTTLSPASSTSPGLQGESTAFQTHPASTHTTPSP---PST 2236

Query: 730  GDYMNMSPVGDSNTSSPSDCYYGPEDPQHKPVLSYYSLPRSFKHTQRPGEPEEGARHQHL 789
                  +PV +S T   S    G     H P  S  S   S K T     P+        
Sbjct: 2237 A----TAPVEESTTYHRSP---GSTPTTHFPASSTTS-GHSEKSTIFHSSPDASGTTPSS 2288

Query: 790  RLSTSSGRLLYAATADDSSSSTSSDSLGGGYCGARLEP------SLPHPHHQVLQPHLPR 843
              ST+SGR   + T+  S  ST   +L G      L        S P      L P    
Sbjct: 2289 AHSTTSGR-GESTTSRISPGSTEITTLPGSTTTPGLSEASTTFYSSPRSPTTTLSPASMT 2347

Query: 844  KVDTAAQTNSRLARP-TRLSLGDPKASTLPRAREQQQQQQPLLHPPEPKSPGEYVNIEFG 902
             +    ++ +  ++P +  S   P ++T P   E+              SPG      F 
Sbjct: 2348 SLGVGEESTTSRSQPGSTHSTVSPASTTTPGLSEESTTVY-------SSSPGSTETTVFP 2400

Query: 903  SDQSGYLSG--PVAFHSSPSVRCPSQLQPAPREEETGTEEYMKMDLGPGRRAAWQES--- 957
               +  + G  P  FHS P+    S       E+ T +    +    PG  A+ Q     
Sbjct: 2401 RTPTTSVRGEEPTTFHSRPA----STHTTLFTEDSTTSGLTEESTAFPGSPASTQTGLPA 2456

Query: 958  --TGVEMGRLGPAPPGAA----SICRPTRAVPSSRGDYMTMQMSCPRQSYVDTSPAAPV- 1010
              T  ++G      P ++    +   P R+  S      T     P  +   T P +P  
Sbjct: 2457 TLTTADLGEESTTFPSSSGSTGTTLSPARSTTSGLVGESTPSRLSPSSTETTTLPGSPTT 2516

Query: 1011 -SYADMRTGIAAEEVSLPRATMAAASSSSAASASPTGPQGAAELAAHSSLLGGPQGPGGM 1069
             S ++  T       S P AT++ A+++S+  +  +    +   + H++         G+
Sbjct: 2517 PSLSEKSTTFYTSPRS-PDATLSPATTTSSGVSEESSTSHSQPGSTHTTAFPDSTTTPGL 2575

Query: 1070 SAFTRVNLSPNRNQSAKVIRADPQGCRRRHSSETFSSTPSAT 1111
            S  +  + S   +    ++ A          S T  S+P +T
Sbjct: 2576 SRHSTTSHSSPGSTDTTLLPASTTTSGPSQESTTSHSSPGST 2617



 Score = 43.9 bits (102), Expect = 0.001
 Identities = 196/924 (21%), Positives = 294/924 (31%), Gaps = 182/924 (19%)

Query: 252  TILEAMRAMSDEFRPRSKSQSSSNCSNPISVPLRRHHLNNPPPSQVGLTRRSRTESITAT 311
            T+L A    S   +  + S SSS  ++    P     L+    S    +    T +    
Sbjct: 3675 TLLPASTTTSGSSQESTTSHSSSGSTDTALSPGSTTALSFGQESTTFHSSPGSTHTTLFP 3734

Query: 312  SPASMVGGKPGSFRVRASSDGEGTMSRPASVDGSPVSPSTNRTHAHRHRGSARLHPPLNH 371
               +  G    S RV +S+    T   PAS     +   +          + + HP   H
Sbjct: 3735 DSTTSSGIVEASTRVHSSTGSPRTTLSPASSTSPGLQGEST---------AFQTHPASTH 3785

Query: 372  SRSIPMPASRCSPSATSPVSLSSSSTSGHGSTSDCLFPRRSSASVSGSPSDGGFISSDEY 431
            +   P P S    +AT+PV  S++     GST    FP  S+ S       G    S  +
Sbjct: 3786 TT--PSPPS----TATAPVEESTTYHRSPGSTPTTHFPASSTTS-------GHSEKSTIF 3832

Query: 432  GSSPCDFRSSFRSVTPDSLGHTPPARGEEELSNYICMGGKGPSTLTAPNGHYILSRGGNG 491
             SSP          TP S   T   RGE   S  I  G    +TL              G
Sbjct: 3833 HSSP-----DASGTTPSSAHSTTSGRGESTTSR-ISPGSTEITTLP-------------G 3873

Query: 492  HRCTPG-----TGLGTSPALAGDEAASAADLDNRFRKRTHSAGTSPTITHQK-TPSQSSV 545
               TPG     T   +SP       + A+       + + ++ + P  TH   +P+ ++ 
Sbjct: 3874 STTTPGLSEASTTFYSSPRSPTTTLSPASMTSLGVGEESTTSRSQPGSTHSTVSPASTTT 3933

Query: 546  ASIEEYTEMMPAYPPGGGSGGRLPGHRHSAFVPTRSYPEEGLEMHPLERRGGHHRPDS-- 603
              + E +  + +  PG       P         T S   E       E    H RP S  
Sbjct: 3934 PGLSEESTTVYSSSPGSTETTVFPRS------TTTSVRRE-------EPTTFHSRPASTH 3980

Query: 604  STLHTDDGYMPMSPGVAPVPSGRKGSGDYMPMSPKSVSAPQQIINPIRRHPQRVDPNGYM 663
            +TL T+D             SG        P SP S                        
Sbjct: 3981 TTLFTEDS----------TTSGLTEESTAFPGSPASTQTG-------------------- 4010

Query: 664  MMSPSGGCSPDIGGGPSSSSSSSNAVPSGTSYGKLWTNGVGGHHSHVLPHPKPPVESSGG 723
               P+   + D+G   ++  SSS +  +  S  +  T+G+ G             ES+  
Sbjct: 4011 --LPATLTTADLGEESTTFPSSSGSTGTKLSPARSTTSGLVG-------------ESTPS 4055

Query: 724  KLLPCTGDYMNM--SPVGDSNTSSPSDCYYGPEDPQ-----HKPVLSYYSLPRSFKHTQR 776
            +L P + +   +  SP   S +   +  Y  P  P           S  S   S  H+Q 
Sbjct: 4056 RLSPSSTETTTLPGSPTTPSLSEKSTTFYTSPRSPDATLSPATTTSSGVSEESSTSHSQ- 4114

Query: 777  PGEPEEGARHQHLRLSTSSGRLLYAATADDSSSSTSSDSLGGGYCGARLEP------SLP 830
            PG     A       +T+SG      T+  S  ST +    G    + L        S P
Sbjct: 4115 PGSTHTTAFPDS---TTTSGLSQEPTTSHSSQGSTEATLSPGSTTASSLGQQSTTFHSSP 4171

Query: 831  HPHHQVLQPHLPRKVDTAAQTNSRLARPTRLSLGD------PKASTLPRAREQQQ--QQQ 882
                  L P      DT        + PT  S G       P +ST    +E+    Q  
Sbjct: 4172 GDTETTLLPD-----DTITSGLVEASTPTHSSTGSLHTTLTPASSTSTGLQEESTTFQSW 4226

Query: 883  PLLHPPEPKSPGEYVNIEFGSDQSGYLSGPVAFHSSPSVRCPSQLQPAPREEETGTEEYM 942
            P      P  P         S  +  +     +HS PS   P+    A       +EE  
Sbjct: 4227 PSSSDTTPSPP---------STTAVPVEVSTTYHSRPS-STPTTHFSASSTTLGRSEEST 4276

Query: 943  KMDLGPGRRAA----WQESTGVEMGRLGPAPPGAASICRPTRAVPSSR-----GDYMTMQ 993
             +   PG         + +T V +G    +P  + S    T A+P S       +  T  
Sbjct: 4277 TVHSSPGATGTALFPTRSATSVLVGEPTTSPISSGS--TETTALPGSTTTAGLSEKSTTF 4334

Query: 994  MSCPRQSYVDTSPAAPVSY-------------ADMRTGIAAEEVSLPRATMAAASSSSAA 1040
             S PR      SPA+  S                M T       ++P  +  + +S S+ 
Sbjct: 4335 YSSPRSPDTTLSPASTTSSGVSEESTTSHSRPGSMHTTAFPSSTTMPGVSQESTASHSSP 4394

Query: 1041 SASPT----GPQGAAELAAHSSLLGGPQGPGGMSAFTRVNLSPNRNQSAKVIRAD-PQGC 1095
             ++ T    G   A+ L   S+      G       T   L P+   ++ ++ A  P   
Sbjct: 4395 GSTDTTLSPGSTTASSLGPESTTFHSSPGS------TETTLLPDNTTASGLLEASTPVHS 4448

Query: 1096 RRRHSSETFSSTPSATRVGNTVPF 1119
                   T S   S TR G +  F
Sbjct: 4449 STGSPHTTLSPAGSTTRQGESTTF 4472



 Score = 41.6 bits (96), Expect = 0.005
 Identities = 165/813 (20%), Positives = 267/813 (32%), Gaps = 93/813 (11%)

Query: 311  TSPASMVGGKPGSFRVRASSDGEGTMSRPASVDGSPVSPSTNRTHAHRHRGSARLHPPLN 370
            ++P+ +  G   +  +  S+   G   +  +   SP SP T    A             +
Sbjct: 608  STPSPISSGSMETTALPGSTTKPGLSEKSTTFYSSPRSPDTTHLPASMTSSGVSEESTTS 667

Query: 371  HSRSIPMPASRCSPSATSPVSLSSSSTSGH---GSTSDCLFPRRSSASVSGSPSDGGFIS 427
            HSR      +   P +T+   LS  ST+ H   G T   L P  ++AS  G         
Sbjct: 668  HSRP-GSTHTTAFPGSTTMPGLSQESTASHSSPGPTDTTLSPGSTTASSLG--------- 717

Query: 428  SDEYGSSPCDFRSSFRSVTPDSLGHTPPARGEEELSNYICMGGKGPSTLTAPNGHYILSR 487
              EY +    F S   S     L     A G  E S  +    + P        H  LS 
Sbjct: 718  -PEYTT----FHSRPGSTETTLLPDNTTASGLLEASMPVHSSTRSP--------HTTLSP 764

Query: 488  GGNGHRCTPGTGLGTSPALAGDEAASAADLDNRFRKRTHSAGTSPTI--THQKTPSQSSV 545
             G+  R    T   + P+      A            T S G+  +I  TH    S +S 
Sbjct: 765  AGSTTRQGESTTFHSWPSSKDTRPAPPTTTSAFVEPSTTSHGSPSSIPTTHISARSTTS- 823

Query: 546  ASIEEYTEMMPAYPPGGGSGGRLPGHRHSAFVPTRSYPEEGLEMHPLERRGGHHRPDSST 605
              +EE T                  H       T  +PE        E     H   SST
Sbjct: 824  GLVEESTTY----------------HSSPGSTQTMHFPESDTTSGRGEESTTSH---SST 864

Query: 606  LHTDDGYMPMSPGVAPVPSGRKGSGDYMPMS--PKSVSAPQQIINPIRRHPQRVDPNGYM 663
             HT       +  +   P+    S      +  P S +   +       H  + D  G +
Sbjct: 865  THTISSAPSTTSALVEEPTSYHSSPGSTATTHFPDSSTTSGRSEESTASHSSQ-DATGTI 923

Query: 664  MMSPSGGCSPDIGGGPSSSSSSSNAVPSGTSYGKLWTNGVGGHHSHVLPHPKPPVESSGG 723
            ++ P+   +  + G  ++S  SS ++ +    G   T G+    +     P+ P  +   
Sbjct: 924  VL-PARSTTSVLLGESTTSPISSGSMETTALPGSTTTPGLSERSTTFHSSPRSPATT--- 979

Query: 724  KLLPCTGDYMNMSPVGDSNTSSPSDCYYGP-EDPQHKPVLSYYSLPRSFKHTQRPGEPEE 782
             L P +     +S    ++ S P   +     D    P LS +S   +  H+  PG  + 
Sbjct: 980  -LSPASTTSSGVSEESTTSRSRPGSTHTTAFPDSTTTPGLSRHS---TTSHSS-PGSTDT 1034

Query: 783  GARHQHLRLSTSSGRLLYAATADDSSSSTSSDSLGGGYCGARLEPSLPHPHHQVLQPHLP 842
                  L  ST++      +T   SSS ++  +L  G   A          H        
Sbjct: 1035 TL----LPASTTTSGPSQESTTSHSSSGSTDTALSPGSTTALSFGQESTTFH-------- 1082

Query: 843  RKVDTAAQTNSRLARPTRLSLGDPKASTLPRAREQQQQQQPLLHPPEPKSPGEYVNIEFG 902
                    T++ L   +  S G  +AST  R        +  L P    SPG        
Sbjct: 1083 ---SNPGSTHTTLFPDSTTSSGIVEAST--RVHSSTGSPRTTLSPASSTSPG------LQ 1131

Query: 903  SDQSGYLSGPVAFHSSPSVRCPSQLQPAPREEETGTEEYMKMDLGPGRRAAWQESTGVEM 962
             + + + + P + H++PS   P     AP EE T               A+   S   E 
Sbjct: 1132 GESTAFQTHPASTHTTPS---PPSTATAPVEESTTYHRSPGSTPTTHFPASSTTSGHSEK 1188

Query: 963  GRLGPAPPGAASIC-RPTRAVPSSRGDYMTMQMSCPRQSYVDTSPAAPVS--YADMRTGI 1019
              +  + P A+        +  S RG+  T ++S P  + + T P +  +   ++  T  
Sbjct: 1189 STIFHSSPDASGTTPSSAHSTTSGRGESTTSRIS-PGSTEITTLPGSTTTPGLSEASTTF 1247

Query: 1020 AAEEVSLPRATMAAASSSSAASASPTGPQGAAELAAHSSLL-GGPQGPGGMSAFTRVNLS 1078
             +   S P  T++ AS +S      +    +   + HS++       PG     T V  S
Sbjct: 1248 YSSPRS-PTTTLSPASMTSLGVGEESTTSRSQPGSTHSTVSPASTTTPGLSEESTTVYSS 1306

Query: 1079 PNRNQSAKVIRADPQGCRRRHSSETFSSTPSAT 1111
               +    V               TF S P++T
Sbjct: 1307 SRGSTETTVFPHSTTTSVHGEEPTTFHSRPAST 1339



 Score = 37.4 bits (85), Expect = 0.090
 Identities = 169/843 (20%), Positives = 274/843 (32%), Gaps = 121/843 (14%)

Query: 328  ASSDGEGTMSRPASVDGSPVSPSTNRTHAHRHRGSARLHPPLNHSRSIPMPASRCSPSAT 387
            ASS   G       V  SPV+ +T    A R   S  +     + RS         P +T
Sbjct: 462  ASSTTLGHSEESTPVHSSPVATATTPPPA-RSATSGHVEESTAYHRS---------PGST 511

Query: 388  SPVSLSSSSTSGHGSTSDCLFPRRSSASVSGSPSDGGFISSDEYGSS-----PCDFRSSF 442
              +    SST+   S     F   ++ + S +PS    ++   Y SS        FR S 
Sbjct: 512  QTMHFPESSTTSGHSEESATFHGSTTHTKSSTPSTTAALAHTSYHSSLGSTETTHFRDS- 570

Query: 443  RSVTPDSLGHTPPARGEEELSNYICMGGKGPSTLTAPNGHYILSRGGNGHRCTPGTGLGT 502
             +++  S          + ++  +   G  PS L   +    +S G       PG+   T
Sbjct: 571  STISGRSEESKASHSSPDAMATTVLPAGSTPSVLVGDSTPSPISSGSMETTALPGS--TT 628

Query: 503  SPALAGDEAASAADLDNRFRKRTH--SAGTSPTITHQKTPSQSSVASIEEY----TEMMP 556
             P L+  E ++      R    TH  ++ TS  ++ + T S S   S        +  MP
Sbjct: 629  KPGLS--EKSTTFYSSPRSPDTTHLPASMTSSGVSEESTTSHSRPGSTHTTAFPGSTTMP 686

Query: 557  AYPPGGGSGGRLPGHRHSAFVP-TRSYPEEGLEMHPLERRGGHHR----PDSSTL----- 606
                   +    PG   +   P + +    G E      R G       PD++T      
Sbjct: 687  GLSQESTASHSSPGPTDTTLSPGSTTASSLGPEYTTFHSRPGSTETTLLPDNTTASGLLE 746

Query: 607  -------HTDDGYMPMSPGVAPVPSGRKGSGDYMPMSPKSVSAPQQIINPIRRHPQRVDP 659
                    T   +  +SP  +    G   +    P S  +  AP    +        V+P
Sbjct: 747  ASMPVHSSTRSPHTTLSPAGSTTRQGESTTFHSWPSSKDTRPAPPTTTSAF------VEP 800

Query: 660  NGYMMMSPSGGCSPDIGGGPSSSSSSSNAVPSGTSYGKLWTNGVGGHHSHVLPHPKPPVE 719
            +     SPS   +  I    S+ S++S  V   T+Y            +  +  P+    
Sbjct: 801  STTSHGSPSSIPTTHI----SARSTTSGLVEESTTYHS------SPGSTQTMHFPESDTT 850

Query: 720  SSGGKLLPCTGDYMNMSPVGDSNTSSPSDCYYGPEDPQHKPVLSYYSLPRSFKHTQRPGE 779
            S  G+         + S    + +S+PS      E+P      SY+S P S   T  P  
Sbjct: 851  SGRGE-----ESTTSHSSTTHTISSAPSTTSALVEEP-----TSYHSSPGSTATTHFPDS 900

Query: 780  PEEGARHQHLRLSTSS----GRLLYAATADDS---SSSTSSDSLGGGYCGARLEPSLPHP 832
                 R +    S SS    G ++  A +  S     ST+S    G      L  S   P
Sbjct: 901  STTSGRSEESTASHSSQDATGTIVLPARSTTSVLLGESTTSPISSGSMETTALPGSTTTP 960

Query: 833  HHQVLQPHLPRKVDTAAQTNSRLARPTRLSLGDPKASTLPRAREQQQQQQPLLHPPEPKS 892
                          + A T   L+  +  S G  + ST  R+R           P    +
Sbjct: 961  GLSERSTTFHSSPRSPATT---LSPASTTSSGVSEESTTSRSRPGSTHTTAF--PDSTTT 1015

Query: 893  PGEYVNIEFGSDQSGYLSGPVAFHSSPSVRCPSQLQPAPREEETGTEEYMKMDLGPGRRA 952
            PG                  ++ HS+ S   P           T T        GP + +
Sbjct: 1016 PG------------------LSRHSTTSHSSPGSTDTTLLPASTTTS-------GPSQES 1050

Query: 953  AW-QESTGVEMGRLGPAPPGAASICRPTRAVPSSRGDYMTMQMSCPRQSYVDTSPAAPVS 1011
                 S+G     L P    A S  + +    S+ G   T         + D++ ++ + 
Sbjct: 1051 TTSHSSSGSTDTALSPGSTTALSFGQESTTFHSNPGSTHT-------TLFPDSTTSSGIV 1103

Query: 1012 YADMRTGIAAEEVSLPRATMAAASSSSAASASPTGPQGAAELAAHSSLLGGPQGPGGMSA 1071
             A  R          PR T++ ASS+S      +        + H++    P  P   +A
Sbjct: 1104 EASTR---VHSSTGSPRTTLSPASSTSPGLQGESTAFQTHPASTHTT----PSPPSTATA 1156

Query: 1072 FTRVNLSPNRNQSAKVIRADPQGCRRRHSSETFSSTPSATRVGNTVPFGAGAAVGGGGGS 1131
                + + +R+  +      P        SE  +   S+     T P  A +   G G S
Sbjct: 1157 PVEESTTYHRSPGSTPTTHFPASSTTSGHSEKSTIFHSSPDASGTTPSSAHSTTSGRGES 1216

Query: 1132 SSS 1134
            ++S
Sbjct: 1217 TTS 1219



 Score = 31.2 bits (69), Expect = 6.4
 Identities = 68/282 (24%), Positives = 95/282 (33%), Gaps = 30/282 (10%)

Query: 288  HLNNPPPSQVGLTRRSRTESITATSPASMVG-GKPGSFRVRASSDGEGTMSRPASVDGSP 346
            H +      + L  RS T  +   S  S +  G   +  +  S+   G   +  +   SP
Sbjct: 4637 HSSQDATGTIVLPARSTTSVLLGESTTSPISSGSMETTALPGSTTTPGLSEKSTTFHSSP 4696

Query: 347  VSPSTNRTHAHRHRGSARLHPPLNHSRSIPMPASRCSPSATSPVSLSSSSTSGH---GST 403
             S  T    A              HS  +   A+  SP+ ++   L   ST+ H   GST
Sbjct: 4697 SSTPTTHFSASSTTLGRSEESTTVHSSPVAT-ATTPSPARSTTSGLVEESTAYHSSPGST 4755

Query: 404  SDCLFPRRSSASVSGSPSDGGFISSDEYGSSPCDFRS-------SFRSVTPDSL------ 450
                FP  S+AS     S     S+    SSP    S       S+ S +P S+      
Sbjct: 4756 QTMHFPESSTASGRSEESRTSHSSTTHTISSPPSTTSALVEEPTSYHS-SPGSIATTHFP 4814

Query: 451  -GHTPPARGEEELSNYICMGGKGPSTLTAPNGHYILSRGGNGHRCTPGTGLGTSPALAGD 509
               T   R EE  +++      G + L A   H+  S      R    T    SP     
Sbjct: 4815 ESSTTSGRSEESTASHSSPDTNGITPLPA---HFTTS-----GRIAESTTFYISPGSMET 4866

Query: 510  EAASAADLDNRFRKRT--HSAGTSPTITHQKTPSQSSVASIE 549
              AS A       K T  +S+  SP  T       SS  S E
Sbjct: 4867 TLASTATTPGLSAKSTILYSSSRSPDQTLSPASMTSSSISGE 4908



 Score = 30.8 bits (68), Expect = 8.4
 Identities = 72/341 (21%), Positives = 110/341 (32%), Gaps = 57/341 (16%)

Query: 266  PRSKSQSSSNCSNPISVPLRRHHLNNPPPSQVGLTRR-----SRTESITAT---SPASMV 317
            P S + S  +  +  S     H +++PP +   L        S   SI  T     ++  
Sbjct: 4761 PESSTASGRSEESRTSHSSTTHTISSPPSTTSALVEEPTSYHSSPGSIATTHFPESSTTS 4820

Query: 318  GGKPGSFRVRASSDGEGTMSRPASVDGSP---------VSPSTNRTHAHRHRGSARLHPP 368
            G    S    +S D  G    PA    S          +SP +  T       S    P 
Sbjct: 4821 GRSEESTASHSSPDTNGITPLPAHFTTSGRIAESTTFYISPGSMETTL----ASTATTPG 4876

Query: 369  LNHSRSIPMPASRCSPSATSPVSLSSSSTSGH--------GSTSDCLFPRRSS------- 413
            L+   +I   +SR      SP S++SSS SG          ST    FP  ++       
Sbjct: 4877 LSAKSTILYSSSRSPDQTLSPASMTSSSISGEPTSLYSQAESTHTTAFPASTTTSGLSQE 4936

Query: 414  --------ASVSGSPSDGGFISS---DEYGSSPCDFRSSFRSVTPDSLGHTPPARGEEEL 462
                     S   + S G   +S    E+ +      S+  +V+P S   T P   EE  
Sbjct: 4937 STTFHSKPGSTETTLSPGSITTSSFAQEFTTPHSQPGSALSTVSPAST--TVPGLSEEST 4994

Query: 463  SNYICMGGKGPSTLTAPNGHYILSRGGNGHRCTPGTGLGTSPALAGDEAASAADLDNRFR 522
            + Y   G    +  +  N   I S+       +PG      PA               F 
Sbjct: 4995 TFYSSPGSTETTAFSHSNTMSIHSQQSTPFPDSPGFTHTVLPATL--TTTDIGQESTAFH 5052

Query: 523  KRTHSAGTSPTITHQKT------PSQSSVASIEEYTEMMPA 557
              + + GT+P             P+   ++    YT + PA
Sbjct: 5053 SSSDATGTTPLPARSTASDLVGEPTTFYISPSPTYTTLFPA 5093


>gi|239508976 PREDICTED: mucin 12, cell surface associated [Homo
            sapiens]
          Length = 2036

 Score = 59.3 bits (142), Expect = 2e-08
 Identities = 200/929 (21%), Positives = 305/929 (32%), Gaps = 197/929 (21%)

Query: 298  GLTRRSRTESITATSPASMVGGKPGSFRVRASSDGEGTM-SRPASVDGSPVSPSTNRTHA 356
            GL+ RS T   +  SPA+ +   P S      S+   T  SRP S   +    ST     
Sbjct: 448  GLSERSTTFHSSPRSPATTLS--PASTTSSGVSEESTTSRSRPGSTHTTAFPDSTTTPGL 505

Query: 357  HRHRGSARLHPPLNHSRSIPMPASRCSPSATSPVSLSSSSTSGHGSTSDCLFPRRSSASV 416
             RH  ++   P    +  +P   +   PS  S  S SSS     GST   L P  ++A  
Sbjct: 506  SRHSTTSHSSPGSTDTTLLPASTTTSGPSQESTTSHSSS-----GSTDTALSPGSTTALS 560

Query: 417  SGSPSDGGFISSDEYGSSPCDFRSSFRSVTPDSLGHTPPARGEEELSNYICMGGKGPSTL 476
             G         S  + S+P    S+  ++ PDS      + G  E S  +      P T 
Sbjct: 561  FGQ-------ESTTFHSNP---GSTHTTLFPDS----TTSSGIVEASTRVHSSTGSPRTT 606

Query: 477  TAPNGHYILSRGGNGHRCTPGTGLGTSPALAGDEAASAADLDNRFRKRTHSAGTSPTITH 536
             +P                      TSP L G+  A           +TH A T  T   
Sbjct: 607  LSP-------------------ASSTSPGLQGESTAF----------QTHPASTHTT--- 634

Query: 537  QKTPSQSSVASIEEYTEMMPAYPPGGGSGGRLPGHRHSAFVPTRSYPEEGLEMHPLERRG 596
              +P  ++ A +EE T           S G  P     A   T  + E+    H      
Sbjct: 635  -PSPPSTATAPVEESTTY-------HRSPGSTPTTHFPASSTTSGHSEKSTIFHSSPDAS 686

Query: 597  G----------HHRPDSSTLHTDDGYMPMS--PGVAPVPSGRKGSGDY--MPMSPKSVSA 642
            G            R +S+T     G   ++  PG    P   + S  +   P SP +  +
Sbjct: 687  GTTPSSAHSTTSGRGESTTSRISPGSTEITTLPGSTTTPGLSEASTTFYSSPRSPTTTLS 746

Query: 643  PQQIIN---PIRRHPQRVDPNG-YMMMSPSGGCSPDIGGGPSSSSSSSNAVPSGTSYGKL 698
            P  + +          R  P   +  +SP+   +P +    ++  SSS      T +   
Sbjct: 747  PASMTSLGVGEESTTSRSQPGSTHSTVSPASTTTPGLSEESTTVYSSSRGSTETTVFPHS 806

Query: 699  WTNGVGGHHS---HVLP-----------------------HPKPPVESSGGKLLPCTGDY 732
             T  V G      H  P                        P  P  +  G  LP T   
Sbjct: 807  TTTSVHGEEPTTFHSRPASTHTTLFTEDSTTSGLTEESTAFPGSPASTQTG--LPAT--- 861

Query: 733  MNMSPVGDSNTSSPSDCYYGPEDPQHKPVLSYYS-----------LPRSFKHTQRPGEPE 781
            +  + +G+ +T+ PS    G    +  P  S  S            P S + T  PG P 
Sbjct: 862  LTTADLGEESTTFPSSS--GSTGTKLSPARSTTSGLVGESTPSRLSPSSTETTTLPGSPT 919

Query: 782  EGARHQHLRLSTSSGRLLYAATADDSSSSTSSDSLGGGYCGARLEPSLPHPHHQVLQPHL 841
              +      LS  S     +  + D++ S ++ +  G    +    S P   H    P  
Sbjct: 920  TPS------LSEKSTTFYTSPRSPDATLSPATTTSSGVSEESSTSHSQPGSTHTTAFPDS 973

Query: 842  PRKVDTAAQT----NSRLARPTRLSLGDPKASTLPRAREQQQQQQPLLHPPEPKSPGEYV 897
                D + +     +S+ +    LS G   AS+L        QQ    H     SPG+  
Sbjct: 974  TTTSDLSQEPTTSHSSQGSTEATLSPGSTTASSL-------GQQSTTFH----SSPGDTE 1022

Query: 898  NIEFGSD--QSGYLSGPVAFHSSP----SVRCPSQLQPAPREEETGTEEYMKMDLGPGRR 951
                  D   SG +      HSS     +   P+    A  +EE+ T +           
Sbjct: 1023 TTLLPDDTITSGLVEASTPTHSSTGSLHTTLTPASSTSAGLQEESTTFQ----------- 1071

Query: 952  AAWQESTGVEMGRLGPAPPGAASICRPTRAVPSSRGDYMTMQMSCPRQSYVDTSPAAPVS 1011
             +W  S+        P+PPG       T A P        +++S    S   ++P    S
Sbjct: 1072 -SWPSSSDTT-----PSPPG-------TTAAP--------VEVSTTYHSRPSSTPTTHFS 1110

Query: 1012 YADMRTGIAAEEV---SLPRATMAAASSSSAASASPTGPQGAAELAAHS---SLLGGPQG 1065
             +    G + E     S P AT  A   + +A++   G    + +++ S   + L G   
Sbjct: 1111 ASSTTLGRSEESTTVHSSPGATGTALFPTRSATSVLVGEPTTSPISSGSTETTALPGSTT 1170

Query: 1066 PGGMSAFTRVNLSPNRNQSAKVIRADPQGCRRRHSSETFSSTPSATRVGNTVPFGAGAAV 1125
              G+S  +    S  R+    +  A          S T  S P +T   +T  F     +
Sbjct: 1171 TAGLSEKSTTFYSSPRSPDTTLSPASTTSSGVSEESTTSHSRPGST---HTTAFPGSTTM 1227

Query: 1126 GGGGGSSSSSEDVKRHSSASFENVWLRPG 1154
             G      S E    HSS    +  L PG
Sbjct: 1228 PG-----VSQESTASHSSPGSTDTTLSPG 1251



 Score = 56.2 bits (134), Expect = 2e-07
 Identities = 187/850 (22%), Positives = 302/850 (35%), Gaps = 138/850 (16%)

Query: 300  TRRSRTESITAT--SPASMVGGKPGSFRVRASSDGEGTMSRPASVDGSPVSPSTNRTHAH 357
            T    TE  TA   SPAS   G P +       +   T    +   G+ +SP+ + T   
Sbjct: 836  TTSGLTEESTAFPGSPASTQTGLPATLTTADLGEESTTFPSSSGSTGTKLSPARSTTSGL 895

Query: 358  RHRGS-ARLHPPLNHSRSIPMPASRCSPSATSPVSLSSSSTSGHGSTSDCLFPRRSSASV 416
                + +RL P    + ++P        S T+P SLS  ST+ + S      PR   A++
Sbjct: 896  VGESTPSRLSPSSTETTTLP-------GSPTTP-SLSEKSTTFYTS------PRSPDATL 941

Query: 417  SGSPSDGGFISSDEYGSSPCDFRSSFRSVTPDSLGHTPPARGEEELSNYICMGGK----G 472
            S + +    +S +E  +S     S+  +  PDS   T     +E  +++   G       
Sbjct: 942  SPATTTSSGVS-EESSTSHSQPGSTHTTAFPDST--TTSDLSQEPTTSHSSQGSTEATLS 998

Query: 473  PSTLTAPNGHYILSRGGNGHRCTPGTGLGTSPALAGDEAASAADLDNRFRKRTHSAGTSP 532
            P + TA +    L +       +PG    T   L  D+  ++  ++      THS+  S 
Sbjct: 999  PGSTTASS----LGQQSTTFHSSPGD---TETTLLPDDTITSGLVEAS--TPTHSSTGSL 1049

Query: 533  TITHQKTPSQSSVASIEEYTEMMPAYPPGGGSGGRLPGHRHSAFVPTRSYPEEGLEMHPL 592
              T   TP+ S+ A ++E +    ++P    +    PG   +    + +Y        P 
Sbjct: 1050 HTT--LTPASSTSAGLQEESTTFQSWPSSSDTTPSPPGTTAAPVEVSTTY-----HSRPS 1102

Query: 593  ERRGGHHRPDSSTLHTDDGYMPMSPGVAPVPSGRKGSGDYMPMSPKSVSAPQQIINPIRR 652
                 H    S+TL    G    S  V   P G  G+  +   S  SV   +   +PI  
Sbjct: 1103 STPTTHFSASSTTL----GRSEESTTVHSSP-GATGTALFPTRSATSVLVGEPTTSPISS 1157

Query: 653  H-------PQRVDPNGYMMMSP---SGGCSPDIGGGPSSSSSSSNAVPSGTSYGKLWTNG 702
                    P      G    S    S   SPD    P+S++SS  +  S TS+ +     
Sbjct: 1158 GSTETTALPGSTTTAGLSEKSTTFYSSPRSPDTTLSPASTTSSGVSEESTTSHSR----- 1212

Query: 703  VGGHHSHVLP----HPKPPVESSGGKLLPCTGDYMNMSPVGDSNTSSPSDCYYGPEDPQH 758
             G  H+   P     P    ES+     P + D   +SP G +  SS      GPE    
Sbjct: 1213 PGSTHTTAFPGSTTMPGVSQESTASHSSPGSTD-TTLSP-GSTTASS-----LGPES--- 1262

Query: 759  KPVLSYYSLPRSFKHTQRPGEPEEGARHQHLRLSTSSGRLLYAATADDSSSSTSSDSLGG 818
                +++S P S + T  P              +T++  LL A+T   SS+ +   +L  
Sbjct: 1263 ---TTFHSSPGSTETTLLPD-------------NTTASGLLEASTPVHSSTGSPHTTLSP 1306

Query: 819  GYCGARLEPSLPHPHHQVLQPHLPRKVDTAAQTNSRLARPTRLSLGDP----------KA 868
                 R   S         +  +P        T S     +  S G P           +
Sbjct: 1307 AGSTTRQGESTTFQSWPSSKDTMP----APPTTTSAFVELSTTSHGSPSSTPTTHFSASS 1362

Query: 869  STLPRAREQQQQQQPLLHPPEPKSPGEYVNIEFGSDQSGYLSGPVAFHSSP----SVRCP 924
            +TL R+ E        +      SP         S  SG +    A+HSSP    ++  P
Sbjct: 1363 TTLGRSEESTTVHSSPVATATTPSPAR-------STTSGLVEESTAYHSSPGSTQTMHFP 1415

Query: 925  SQLQPAPREEETGTEEYM---KMDLGPGRRAAWQESTGVEMGRLGPAPPGAASICRPTRA 981
                 + R EE+ T        +   P   +A  E    E      +P   A+   P  +
Sbjct: 1416 ESSTASGRSEESRTSHSSTTHTISSPPSTTSALVE----EPTSYHSSPGSIATTHFPESS 1471

Query: 982  VPSSRGDYMTMQMSCPRQSYVDTSPAAPVSYADMRTGIAAEEVSLPRATMAAASSSSAAS 1041
              S R +  T   S P     DT+   P+      +G  AE  +    +  +  ++ A++
Sbjct: 1472 TTSGRSEESTASHSSP-----DTNGITPLPAHFTTSGRIAESTTF-YISPGSMETTLAST 1525

Query: 1042 ASPTGPQGAAELAAHSSLLGGPQGPGGMSAFTRVNLSPNRNQSAKVIRADPQGCRRRHSS 1101
            A+  G    + +   S L+G P         T   +SP+   +  +  A          S
Sbjct: 1526 ATTPGLSAKSTILYTSDLVGEP---------TTFYISPSPTYTT-LFPASSSTSGLTEES 1575

Query: 1102 ETFSSTPSAT 1111
             TF ++PS T
Sbjct: 1576 TTFHTSPSFT 1585



 Score = 48.5 bits (114), Expect = 4e-05
 Identities = 183/860 (21%), Positives = 272/860 (31%), Gaps = 163/860 (18%)

Query: 305  TESITATSPASMVGGKPGSF---RVRASSDGEGTMSRPASVDGSPVSPST-----NRTHA 356
            T +     P++   G P S     + A S   G +    +   SP S  T     + T +
Sbjct: 279  TTTSAFVEPSTTSHGSPSSIPTTHISARSTTSGLVEESTTYHSSPGSTQTMHFPESDTTS 338

Query: 357  HRHRGSARLHPPLNHSRSIPMPASRCSPSATSP-VSLSSSSTSGHGSTSDCLFPRRSSAS 415
             R   S   H    H+ S        +PS TS  V   +S  S  GST+   FP  S+ S
Sbjct: 339  GRGEESTTSHSSTTHTIS-------SAPSTTSALVEEPTSYHSSPGSTATTHFPDSSTTS 391

Query: 416  VSGSPSDGGFISSDEYGSSPCDFRSSFRSVTPDSLGHTPPARGEEELSNYICMGGKGPST 475
                 S     S D  G+     RS+  SV       +P + G  E +         P +
Sbjct: 392  GRSEESTASHSSQDATGTIVLPARST-TSVLLGESTTSPISSGSMETTAL-------PGS 443

Query: 476  LTAPNGHYILSRGGNGHRCTPGTGLGTSPALAGDEAASAADLDNRFRK-RTHSAG----- 529
             T P    +  R    H          SPA       S     +R R   TH+       
Sbjct: 444  TTTPG---LSERSTTFHSSPRSPATTLSPASTTSSGVSEESTTSRSRPGSTHTTAFPDST 500

Query: 530  TSPTITHQKTPSQSSVASIEEYTEMMPA-YPPGGGSGGRLPGHRHSAFVPTR-------- 580
            T+P ++   T S SS  S +  T ++PA     G S      H  S    T         
Sbjct: 501  TTPGLSRHSTTSHSSPGSTD--TTLLPASTTTSGPSQESTTSHSSSGSTDTALSPGSTTA 558

Query: 581  -SYPEEGLEMHPLERRGGHHR---PDSST----------LHTDDG--YMPMSPGVAPVPS 624
             S+ +E    H     G  H    PDS+T          +H+  G     +SP  +  P 
Sbjct: 559  LSFGQESTTFH--SNPGSTHTTLFPDSTTSSGIVEASTRVHSSTGSPRTTLSPASSTSP- 615

Query: 625  GRKG----------SGDYMPMSPKSVSAPQQIINPIRRHPQRVDPNGYMMMSPSGG---- 670
            G +G          S    P  P + +AP +      R P       +   S + G    
Sbjct: 616  GLQGESTAFQTHPASTHTTPSPPSTATAPVEESTTYHRSPGSTPTTHFPASSTTSGHSEK 675

Query: 671  -----CSPDIGGGPSSS----------SSSSNAVPSGTSY----GKLWTNGVGGHHSHVL 711
                  SPD  G   SS          S++S   P  T      G   T G+    +   
Sbjct: 676  STIFHSSPDASGTTPSSAHSTTSGRGESTTSRISPGSTEITTLPGSTTTPGLSEASTTFY 735

Query: 712  PHPKPPVESSGGKLLPCTG-----------DYMNMSPVGDSNTSSP-----SDCYYGPED 755
              P+ P  +     +   G                S V  ++T++P     S   Y    
Sbjct: 736  SSPRSPTTTLSPASMTSLGVGEESTTSRSQPGSTHSTVSPASTTTPGLSEESTTVYSSSR 795

Query: 756  PQHKPVL---------------SYYSLPRSFKHT------QRPGEPEEGARHQHLRLSTS 794
               +  +               +++S P S   T         G  EE         ST 
Sbjct: 796  GSTETTVFPHSTTTSVHGEEPTTFHSRPASTHTTLFTEDSTTSGLTEESTAFPGSPASTQ 855

Query: 795  SGRLLYAATADDSSSSTSSDSLGGGYCGARLEPSLPHPHHQVLQPHLPRKVDTAAQTNSR 854
            +G      TAD    ST+  S   G  G +L P+       V +    R   ++ +T + 
Sbjct: 856  TGLPATLTTADLGEESTTFPS-SSGSTGTKLSPARSTTSGLVGESTPSRLSPSSTETTTL 914

Query: 855  LARPTRLSLGDPKAS--TLPRAREQQQQQQPLLHPPEPKSPGEYVNIEFGSDQSGYLSGP 912
               PT  SL +   +  T PR+            P    SP    +     + S   S P
Sbjct: 915  PGSPTTPSLSEKSTTFYTSPRS------------PDATLSPATTTSSGVSEESSTSHSQP 962

Query: 913  VAFHSS--PSVRCPSQLQPAPREEETGTEEYMKMDLGPGRRAAWQESTGVEMGRLGPAPP 970
             + H++  P     S L   P    + ++   +  L PG   A   S G +      +P 
Sbjct: 963  GSTHTTAFPDSTTTSDLSQEPTTSHS-SQGSTEATLSPGSTTA--SSLGQQSTTFHSSPG 1019

Query: 971  GAASICRPTRAVPSSRGDYMTMQMSCPRQSYVDTSPAAPVSYADMRTGIAAEEVSLPRAT 1030
               +   P   + S   +  T   S     +   +PA+  S      G+  E       T
Sbjct: 1020 DTETTLLPDDTITSGLVEASTPTHSSTGSLHTTLTPASSTS-----AGLQEES-----TT 1069

Query: 1031 MAAASSSSAASASPTGPQGA 1050
              +  SSS  + SP G   A
Sbjct: 1070 FQSWPSSSDTTPSPPGTTAA 1089



 Score = 41.6 bits (96), Expect = 0.005
 Identities = 165/813 (20%), Positives = 267/813 (32%), Gaps = 93/813 (11%)

Query: 311  TSPASMVGGKPGSFRVRASSDGEGTMSRPASVDGSPVSPSTNRTHAHRHRGSARLHPPLN 370
            ++P+ +  G   +  +  S+   G   +  +   SP SP T    A             +
Sbjct: 95   STPSPISSGSMETTALPGSTTKPGLSEKSTTFYSSPRSPDTTHLPASMTSSGVSEESTTS 154

Query: 371  HSRSIPMPASRCSPSATSPVSLSSSSTSGH---GSTSDCLFPRRSSASVSGSPSDGGFIS 427
            HSR      +   P +T+   LS  ST+ H   G T   L P  ++AS  G         
Sbjct: 155  HSRP-GSTHTTAFPGSTTMPGLSQESTASHSSPGPTDTTLSPGSTTASSLG--------- 204

Query: 428  SDEYGSSPCDFRSSFRSVTPDSLGHTPPARGEEELSNYICMGGKGPSTLTAPNGHYILSR 487
              EY +    F S   S     L     A G  E S  +    + P        H  LS 
Sbjct: 205  -PEYTT----FHSRPGSTETTLLPDNTTASGLLEASMPVHSSTRSP--------HTTLSP 251

Query: 488  GGNGHRCTPGTGLGTSPALAGDEAASAADLDNRFRKRTHSAGTSPTI--THQKTPSQSSV 545
             G+  R    T   + P+      A            T S G+  +I  TH    S +S 
Sbjct: 252  AGSTTRQGESTTFHSWPSSKDTRPAPPTTTSAFVEPSTTSHGSPSSIPTTHISARSTTS- 310

Query: 546  ASIEEYTEMMPAYPPGGGSGGRLPGHRHSAFVPTRSYPEEGLEMHPLERRGGHHRPDSST 605
              +EE T                  H       T  +PE        E     H   SST
Sbjct: 311  GLVEESTTY----------------HSSPGSTQTMHFPESDTTSGRGEESTTSH---SST 351

Query: 606  LHTDDGYMPMSPGVAPVPSGRKGSGDYMPMS--PKSVSAPQQIINPIRRHPQRVDPNGYM 663
             HT       +  +   P+    S      +  P S +   +       H  + D  G +
Sbjct: 352  THTISSAPSTTSALVEEPTSYHSSPGSTATTHFPDSSTTSGRSEESTASHSSQ-DATGTI 410

Query: 664  MMSPSGGCSPDIGGGPSSSSSSSNAVPSGTSYGKLWTNGVGGHHSHVLPHPKPPVESSGG 723
            ++ P+   +  + G  ++S  SS ++ +    G   T G+    +     P+ P  +   
Sbjct: 411  VL-PARSTTSVLLGESTTSPISSGSMETTALPGSTTTPGLSERSTTFHSSPRSPATT--- 466

Query: 724  KLLPCTGDYMNMSPVGDSNTSSPSDCYYGP-EDPQHKPVLSYYSLPRSFKHTQRPGEPEE 782
             L P +     +S    ++ S P   +     D    P LS +S   +  H+  PG  + 
Sbjct: 467  -LSPASTTSSGVSEESTTSRSRPGSTHTTAFPDSTTTPGLSRHS---TTSHSS-PGSTDT 521

Query: 783  GARHQHLRLSTSSGRLLYAATADDSSSSTSSDSLGGGYCGARLEPSLPHPHHQVLQPHLP 842
                  L  ST++      +T   SSS ++  +L  G   A          H        
Sbjct: 522  TL----LPASTTTSGPSQESTTSHSSSGSTDTALSPGSTTALSFGQESTTFH-------- 569

Query: 843  RKVDTAAQTNSRLARPTRLSLGDPKASTLPRAREQQQQQQPLLHPPEPKSPGEYVNIEFG 902
                    T++ L   +  S G  +AST  R        +  L P    SPG        
Sbjct: 570  ---SNPGSTHTTLFPDSTTSSGIVEAST--RVHSSTGSPRTTLSPASSTSPG------LQ 618

Query: 903  SDQSGYLSGPVAFHSSPSVRCPSQLQPAPREEETGTEEYMKMDLGPGRRAAWQESTGVEM 962
             + + + + P + H++PS   P     AP EE T               A+   S   E 
Sbjct: 619  GESTAFQTHPASTHTTPS---PPSTATAPVEESTTYHRSPGSTPTTHFPASSTTSGHSEK 675

Query: 963  GRLGPAPPGAASIC-RPTRAVPSSRGDYMTMQMSCPRQSYVDTSPAAPVS--YADMRTGI 1019
              +  + P A+        +  S RG+  T ++S P  + + T P +  +   ++  T  
Sbjct: 676  STIFHSSPDASGTTPSSAHSTTSGRGESTTSRIS-PGSTEITTLPGSTTTPGLSEASTTF 734

Query: 1020 AAEEVSLPRATMAAASSSSAASASPTGPQGAAELAAHSSLL-GGPQGPGGMSAFTRVNLS 1078
             +   S P  T++ AS +S      +    +   + HS++       PG     T V  S
Sbjct: 735  YSSPRS-PTTTLSPASMTSLGVGEESTTSRSQPGSTHSTVSPASTTTPGLSEESTTVYSS 793

Query: 1079 PNRNQSAKVIRADPQGCRRRHSSETFSSTPSAT 1111
               +    V               TF S P++T
Sbjct: 794  SRGSTETTVFPHSTTTSVHGEEPTTFHSRPAST 826


>gi|209915594 transcription factor 3 isoform E47 [Homo sapiens]
          Length = 651

 Score = 53.5 bits (127), Expect = 1e-06
 Identities = 71/266 (26%), Positives = 101/266 (37%), Gaps = 32/266 (12%)

Query: 902  GSDQSGYLSGPVAFHSSPSVRCPSQLQPAPREEETGTEEYMKMDLGPGRRAAWQESTGVE 961
            G  Q+G+LSG +A +S      P  L P+  +   GT +Y     G  RR A   S   +
Sbjct: 119  GLTQAGFLSGELALNS------PGPLSPSGMK---GTSQYYPSYSGSSRRRAADGSLDTQ 169

Query: 962  MGRLGPAPPGAASICRPTRAVPSSRGDYMTMQMSCPRQSYVDTSPAAPVSYADMRTGIAA 1021
              ++   PPG  S   P    PSS  DY     + P      ++  AP   AD     +A
Sbjct: 170  PKKVRKVPPGLPSSVYP----PSSGEDYGRDATAYPSAKTPSSTYPAPFYVADGSLHPSA 225

Query: 1022 EEVSLPRATMAAASSSSAASASPTGPQGAAELAAHSSLLGGPQGPGGMSAFTRVNLSPNR 1081
            E  S P            +S  P  P              GP G  G S+ T   L  + 
Sbjct: 226  ELWSPPGQAGFGPMLGGGSSPLPLPPG------------SGPVGSSGSSS-TFGGLHQHE 272

Query: 1082 NQSAKVIRADPQGCRRRHSSETFSSTPSATRVG---NTVPF-GAGAAVGGGGGSSSSSED 1137
                ++  A+  G     S+ +FSS P AT  G   +T P  GA + +G  G ++ SS D
Sbjct: 273  RMGYQLHGAEVNG--GLPSASSFSSAPGATYGGVSSHTPPVSGADSLLGSRGTTAGSSGD 330

Query: 1138 VKRHSSASFENVWLRPGELGGAPKEP 1163
                + AS  +          +P  P
Sbjct: 331  ALGKALASIYSPDHSSNNFSSSPSTP 356



 Score = 47.0 bits (110), Expect = 1e-04
 Identities = 87/369 (23%), Positives = 128/369 (34%), Gaps = 87/369 (23%)

Query: 294 PSQVGLTRRSRTESITATSPASMVGGKPG-SFRVRASSDGEGTMSRPASVDGSPVSPSTN 352
           PS  G +RR   +    T P  +    PG    V   S GE    R A+   S  +PS+ 
Sbjct: 151 PSYSGSSRRRAADGSLDTQPKKVRKVPPGLPSSVYPPSSGED-YGRDATAYPSAKTPSST 209

Query: 353 RTHAHRHRGSARLHP--------------PLNHSRSIPMPASRCSPSATSPVSLSSSSTS 398
              A  +     LHP              P+    S P+P     P  + PV  S SS++
Sbjct: 210 YP-APFYVADGSLHPSAELWSPPGQAGFGPMLGGGSSPLPL----PPGSGPVGSSGSSST 264

Query: 399 GHGSTSDCLFPRRSSASVSGSPSDGGFISSDEYGSSPCDFRSSFRSVTPDSLGHTPPARG 458
             G         R    + G+  +GG  S+  + S+P    +++  V+     HTPP  G
Sbjct: 265 FGGLHQH----ERMGYQLHGAEVNGGLPSASSFSSAP---GATYGGVS----SHTPPVSG 313

Query: 459 EEEL--SNYICMGGKGPSTLTAPNGHYILSRGGNGHRCTPGTGLGTSPALAGDEAASAA- 515
            + L  S     G  G +   A    Y      N    +P T +G+   LAG      A 
Sbjct: 314 ADSLLGSRGTTAGSSGDALGKALASIYSPDHSSNNFSSSPSTPVGSPQGLAGTSQWPRAG 373

Query: 516 ----------------------DLDNRFR-KRTHSAGTSPTITHQKTPSQSSVASIEEYT 552
                                  LD      R+H+ GT+  + H   P   ++AS     
Sbjct: 374 APGALSPSYDGGLHGLQSKIEDHLDEAIHVLRSHAVGTAGDM-HTLLPGHGALAS----- 427

Query: 553 EMMPAYPPGGGSGGRLPGHRHSAFVPTRSYPEEGLEMHPLERRGGHHRPDSSTLHTDDGY 612
                    G +G    G RH+  V   S+PE+GL               S++L  +   
Sbjct: 428 ---------GFTGPMSLGGRHAGLV-GGSHPEDGL-------------AGSTSLMHNHAA 464

Query: 613 MPMSPGVAP 621
           +P  PG  P
Sbjct: 465 LPSQPGTLP 473


>gi|27777636 transcription factor 3 isoform E12 [Homo sapiens]
          Length = 654

 Score = 53.5 bits (127), Expect = 1e-06
 Identities = 71/266 (26%), Positives = 101/266 (37%), Gaps = 32/266 (12%)

Query: 902  GSDQSGYLSGPVAFHSSPSVRCPSQLQPAPREEETGTEEYMKMDLGPGRRAAWQESTGVE 961
            G  Q+G+LSG +A +S      P  L P+  +   GT +Y     G  RR A   S   +
Sbjct: 119  GLTQAGFLSGELALNS------PGPLSPSGMK---GTSQYYPSYSGSSRRRAADGSLDTQ 169

Query: 962  MGRLGPAPPGAASICRPTRAVPSSRGDYMTMQMSCPRQSYVDTSPAAPVSYADMRTGIAA 1021
              ++   PPG  S   P    PSS  DY     + P      ++  AP   AD     +A
Sbjct: 170  PKKVRKVPPGLPSSVYP----PSSGEDYGRDATAYPSAKTPSSTYPAPFYVADGSLHPSA 225

Query: 1022 EEVSLPRATMAAASSSSAASASPTGPQGAAELAAHSSLLGGPQGPGGMSAFTRVNLSPNR 1081
            E  S P            +S  P  P              GP G  G S+ T   L  + 
Sbjct: 226  ELWSPPGQAGFGPMLGGGSSPLPLPPG------------SGPVGSSGSSS-TFGGLHQHE 272

Query: 1082 NQSAKVIRADPQGCRRRHSSETFSSTPSATRVG---NTVPF-GAGAAVGGGGGSSSSSED 1137
                ++  A+  G     S+ +FSS P AT  G   +T P  GA + +G  G ++ SS D
Sbjct: 273  RMGYQLHGAEVNG--GLPSASSFSSAPGATYGGVSSHTPPVSGADSLLGSRGTTAGSSGD 330

Query: 1138 VKRHSSASFENVWLRPGELGGAPKEP 1163
                + AS  +          +P  P
Sbjct: 331  ALGKALASIYSPDHSSNNFSSSPSTP 356



 Score = 47.0 bits (110), Expect = 1e-04
 Identities = 87/369 (23%), Positives = 128/369 (34%), Gaps = 87/369 (23%)

Query: 294 PSQVGLTRRSRTESITATSPASMVGGKPG-SFRVRASSDGEGTMSRPASVDGSPVSPSTN 352
           PS  G +RR   +    T P  +    PG    V   S GE    R A+   S  +PS+ 
Sbjct: 151 PSYSGSSRRRAADGSLDTQPKKVRKVPPGLPSSVYPPSSGED-YGRDATAYPSAKTPSST 209

Query: 353 RTHAHRHRGSARLHP--------------PLNHSRSIPMPASRCSPSATSPVSLSSSSTS 398
              A  +     LHP              P+    S P+P     P  + PV  S SS++
Sbjct: 210 YP-APFYVADGSLHPSAELWSPPGQAGFGPMLGGGSSPLPL----PPGSGPVGSSGSSST 264

Query: 399 GHGSTSDCLFPRRSSASVSGSPSDGGFISSDEYGSSPCDFRSSFRSVTPDSLGHTPPARG 458
             G         R    + G+  +GG  S+  + S+P    +++  V+     HTPP  G
Sbjct: 265 FGGLHQH----ERMGYQLHGAEVNGGLPSASSFSSAP---GATYGGVS----SHTPPVSG 313

Query: 459 EEEL--SNYICMGGKGPSTLTAPNGHYILSRGGNGHRCTPGTGLGTSPALAGDEAASAA- 515
            + L  S     G  G +   A    Y      N    +P T +G+   LAG      A 
Sbjct: 314 ADSLLGSRGTTAGSSGDALGKALASIYSPDHSSNNFSSSPSTPVGSPQGLAGTSQWPRAG 373

Query: 516 ----------------------DLDNRFR-KRTHSAGTSPTITHQKTPSQSSVASIEEYT 552
                                  LD      R+H+ GT+  + H   P   ++AS     
Sbjct: 374 APGALSPSYDGGLHGLQSKIEDHLDEAIHVLRSHAVGTAGDM-HTLLPGHGALAS----- 427

Query: 553 EMMPAYPPGGGSGGRLPGHRHSAFVPTRSYPEEGLEMHPLERRGGHHRPDSSTLHTDDGY 612
                    G +G    G RH+  V   S+PE+GL               S++L  +   
Sbjct: 428 ---------GFTGPMSLGGRHAGLV-GGSHPEDGL-------------AGSTSLMHNHAA 464

Query: 613 MPMSPGVAP 621
           +P  PG  P
Sbjct: 465 LPSQPGTLP 473


>gi|118572613 splicing coactivator subunit SRm300 [Homo sapiens]
          Length = 2752

 Score = 51.6 bits (122), Expect = 5e-06
 Identities = 151/685 (22%), Positives = 239/685 (34%), Gaps = 121/685 (17%)

Query: 265  RPRSKSQSSSNCSNPISVPLRRHHLNNPPPSQVGLTRRSRTESITATSPASMVGGK-PGS 323
            R RS S SSS+ S   + P  R+H  +  P     + R    S  + SP  +   + PG 
Sbjct: 2076 RRRSASGSSSDRSRSATPPATRNHSGSRTPPVALNSSRMSCFSRPSMSPTPLDRCRSPGM 2135

Query: 324  FRVRASSDGEGTMSRPAS---VDG-SPVSPSTNRTHAHRHRGSARL------------HP 367
                 SS    ++ + A    +DG  P  P   RT    +   +R+             P
Sbjct: 2136 LEPLGSSRTPMSVLQQAGGSMMDGPGPRIPDHQRTSVPENHAQSRIALALTAISLGTARP 2195

Query: 368  PLNHSRS------------IPMPASRCSPSAT--SPVSLSSSSTSGHGSTSDCLFPRRSS 413
            P + S +            +P+ + R +P+A   S +  +S++     S      P   +
Sbjct: 2196 PPSMSAAGLAARMSQVPAPVPLMSLRTAPAANLASRIPAASAAAMNLASARTPAIPTAVN 2255

Query: 414  ASVSGSPSDGGFISSDEYGSSPCDFRSSFRSVTPDSLGHTPPARGEEELSNYICMGGKGP 473
             + S +P+           ++  +  S   +V P ++    P        N    G + P
Sbjct: 2256 LADSRTPA----------AAAAMNLASPRTAVAPSAVNLADPRTPTAPAVNLA--GARTP 2303

Query: 474  STLTAPNGHYILSRGGNGHRCTPGTGLGTSPALAGDEAASAADLDNRFRKRTHSAGTSPT 533
            + L A      LS  G+G   TP T      +    +A ++A+L      R+  A     
Sbjct: 2304 AALAA------LSLTGSG---TPPTAANYPSSSRTPQAPASANLVG---PRSAHATAPVN 2351

Query: 534  ITHQKTPSQSSVASIEEYTEMMPAYPPGGGSGGRLPGHRHSAFVPTRSYPE-EGLEMHPL 592
            I   +T +  + AS+     M PA      SG  L   R    VP  +Y    G    PL
Sbjct: 2352 IAGSRTAAALAPASLTS-ARMAPAL-----SGANLTSPR----VPLSAYERVSGRTSPPL 2401

Query: 593  ERRGGHHRPDSSTLHTDDGYMPMSPGVAPVPSGRKGSGDYMPMSPKSVSAPQQIINPIRR 652
              R     P S+   +      M+   AP PS R G            +  Q ++ P + 
Sbjct: 2402 LDRARSRTPPSAPSQSR-----MTSERAPSPSSRMGQ-----------APSQSLLPPAQD 2445

Query: 653  HPQRVDPNGYMMMS--------PSGGCSPDIGGGPSSSSSSSNAVPSGTSYGKLWTNGVG 704
             P+   P+ +   S        P  G S  +  G  ++++SS    +G   G L     G
Sbjct: 2446 QPRSPVPSAFSDQSRCLIAQTTPVAG-SQSLSSGAVATTTSS----AGDHNGMLSVPAPG 2500

Query: 705  GHHSHVLPHP--------------KPPVE------SSGGKLLPCTGDYMNMSPVGDSNTS 744
              HS V   P              +P  E      SS       +    + S     ++S
Sbjct: 2501 VPHSDVGEPPASTGAQQPSALAALQPAKERRSSSSSSSSSSSSSSSSSSSSSSSSSGSSS 2560

Query: 745  SPSDCYYGPEDPQH--KPVLSYYSLPRSFKHTQRPGEPEEGARHQHLRLSTSSGRLLYAA 802
            S S+    P  P+   K V S    P+      RP EP    R +    S+SS     ++
Sbjct: 2561 SDSEGSSLPVQPEVALKRVPSPTPAPKEAVREGRPPEPTPAKRKRRSSSSSSSSSSSSSS 2620

Query: 803  TADDSSSS----TSSDSLGGGYCGARLEPSLPHPHHQVLQPHLPRKVDTAAQTNSRLARP 858
            ++  SSSS    +SS S       +   PS   P  Q L      K     +  SR  R 
Sbjct: 2621 SSSSSSSSSSSSSSSSSSSSSSSSSSSSPSPAKPGPQALPKPASPKKPPPGERRSRSPRK 2680

Query: 859  TRLSLGDPKASTLPRAREQQQQQQP 883
               SL D ++ +      ++   QP
Sbjct: 2681 PIDSLRDSRSLSYSPVERRRPSPQP 2705



 Score = 48.5 bits (114), Expect = 4e-05
 Identities = 189/947 (19%), Positives = 320/947 (33%), Gaps = 99/947 (10%)

Query: 267  RSKSQSSSNCSNPISVPLRRHHLNNPPPSQVGLTRRSRTESITATSPASMVGGKP--GSF 324
            RS+S SS   +   + P R    ++PPP Q   T   ++ S ++  P    G  P  GS 
Sbjct: 796  RSRSGSSQPKAKSRTPPRRSRSSSSPPPKQKSKTPSRQSHSSSSPHPKVKSGTPPRQGSI 855

Query: 325  RVRASSDGEGTMSRPASVDGSPVSPSTNRTHAHRHRGSARLHPPLNHS---RSIPMPASR 381
                +++   T  R +  + SP     +RT + RH  S    P +  S   R  P  +S 
Sbjct: 856  TSPQANEQSVTPQRRSCFESSPDPELKSRTPS-RHSCSGSSPPRVKSSTPPRQSPSRSSS 914

Query: 382  CSPSATSPVSLSSSSTSGHGSTSDCLFPRRSSASVSGSPSDGGFISS------DEYGSSP 435
              P   + +S    S SG  S S      R++   S S S    + S         GSS 
Sbjct: 915  PQPKVKAIISPRQRSHSGSSSPSPSRVTSRTTPRRSRSVSPCSNVESRLLPRYSHSGSSS 974

Query: 436  CDFRSSFRSVTPDSLGHT------PPARGEEELSNYICMGGKGPSTLTAPNGHYILSRGG 489
             D  +  +  TP    H+      P  + +      +  G K P          + S  G
Sbjct: 975  PD--TKVKPETPPRQSHSGSISPYPKVKAQTPPGPSL-SGSKSPCPQEKSKDSLVQSCPG 1031

Query: 490  NGHRCTPGTGLGTSPALAGDEAASAADLDNRFRKRTHSAGTSPTITHQKTPSQSSVASIE 549
            +   C  G    T P   G+     + L  + + +T     S T + +   S S   S++
Sbjct: 1032 SLSLCA-GVKSSTPP---GESYFGVSSLQLKGQSQTSPDHRSDTSSPEVRQSHSESPSLQ 1087

Query: 550  EYTEMMPAYPPGGGSGGRLPGHRHSAFVPTRSYPEEGLEMHPLERRGGHHRPDSSTLHTD 609
              ++     P GG S    P    ++  P R    E     P+ + G    P+ S   +D
Sbjct: 1088 SKSQ---TSPKGGRSRSSSPVTELASRSPIRQDRGE-FSASPMLKSG--MSPEQSRFQSD 1141

Query: 610  DGYMPMSPGVAPVPSGRKGSGD-----YMPMSPKSVSAPQQIINPIRRHPQRVDPNGYMM 664
                P     + +   R  + +      +P    + ++P +  +     P +  P   ++
Sbjct: 1142 SSSYPTVDSNSLLGQSRLETAESKEKMALPPQEDATASPPRQKDKFSPFPVQDRPESSLV 1201

Query: 665  MSPSGGCSPDIGGGPSSS---SSSSNAVPSGTSYGKLW------TNGVGGHHSHVLPHPK 715
               +    P    G  SS      ++A+P+ +   +L           G   SH+    K
Sbjct: 1202 FKDTLRTPPRERSGAGSSPETKEQNSALPTSSQDEELMEVVEKSEEPAGQILSHLSSELK 1261

Query: 716  PPVESSGGKLLPCTGDYMNMSPVGDSNTS----------SPSDCYYGPE-DPQHKPVL-- 762
              + +S  +  P   +   +S   D + S          S +  + GP   P+HK +   
Sbjct: 1262 -EMSTSNFESSPEVEERPAVSLTLDQSQSQASLEAVEVPSMASSWGGPHFSPEHKELSNS 1320

Query: 763  ----SYYSLPRSFKHTQRPGEPEEGARHQHLRLSTSSGRLLYAATADDSSSSTSSDSLGG 818
                + +  P  F+++   G          ++    +G  L     D S       +   
Sbjct: 1321 PLRENSFGSPLEFRNSGPLGTEMNTGFSSEVK-EDLNGPFLNQLETDPSLDMKEQSTRSS 1379

Query: 819  GYCGARLEPSLPH-----PHHQVLQPHLPRKVDTAAQTNSRLARPTRLSLGDPKASTLPR 873
            G+  + L P          +  +  P L     T ++  S  A    +  G P+  +  R
Sbjct: 1380 GHSSSELSPDAVEKAGMSSNQSISSPVLDAVPRTPSRERSSSASSPEMKDGLPRTPS-RR 1438

Query: 874  ARE------QQQQQQPLLHPPEPKSPGEY---VNIEFGSDQSGYLSGPVAFHSSPSVRCP 924
            +R       +     P  H     SPG          G  +      P A   +P  R  
Sbjct: 1439 SRSGSSPGLRDGSGTPSRHSLSGSSPGMKDIPRTPSRGRSECDSSPEPKALPQTPRPRSR 1498

Query: 925  SQLQP-------APREEETGTEEYMKMDLGPGRRAAWQESTGVEMGRLGPAPPGAASICR 977
            S   P        P+ E +G+E  +       R    Q S       L   P  +     
Sbjct: 1499 SPSSPELNNKCLTPQRERSGSESSVDQKT-VARTPLGQRSRSGSSQELDVKPSASPQERS 1557

Query: 978  PTRAVPSSRGDYMT-MQMSCPRQSYVDTSPAAPVSYADMRTGIAAEEVSLPRATMAAASS 1036
             + + P S+    T ++      S  +    + +S    R+G + E    PRA    A S
Sbjct: 1558 ESDSSPDSKAKTRTPLRQRSRSGSSPEVDSKSRLSPRRSRSGSSPEVKDKPRAA-PRAQS 1616

Query: 1037 SSAASASPTGPQGAA---ELAAHSSLLGGPQGPGGMSAFTRVNLSPNRNQSAKVIRADPQ 1093
             S +S  P  P   A      + SS  G    P G S+       P ++++A+      +
Sbjct: 1617 GSDSSPEPKAPAPRALPRRSRSGSSSKGRGPSPEGSSSTESSPEHPPKSRTAR------R 1670

Query: 1094 GCRRRHSSETFSSTPSATRVGNTVP-FGAGAAVGGGGGSSSSSEDVK 1139
            G R     +T S TP   R   + P     A +     S+SSS + +
Sbjct: 1671 GSRSSPEPKTKSRTPPRRRSSRSSPELTRKARLSRRSRSASSSPETR 1717



 Score = 40.8 bits (94), Expect = 0.008
 Identities = 209/989 (21%), Positives = 331/989 (33%), Gaps = 193/989 (19%)

Query: 258  RAMSDEFRPRSKSQSSSNCSNPISVPLRRHHLNNPPPSQVGLTRRSRTESITATSPASMV 317
            R+ +   R RS+S++S     P+S   RR   +  PP    +TRR R+ S T T+     
Sbjct: 1901 RSRTSVTRRRSRSRAS-----PVS---RRRSRSRTPP----VTRR-RSRSRTPTTRRRSR 1947

Query: 318  GGKPGSFRVRASSDGEGTMSRPASVDGSPVSPSTNRTHAH---RHRGSARLHPPLNH-SR 373
               P   R R+ S       R +    SP++   +R+      R R  +R  P     SR
Sbjct: 1948 SRTPPVTRRRSRSRTPPVTRRRSRSRTSPITRRRSRSRTSPVTRRRSRSRTSPVTRRRSR 2007

Query: 374  SIPMPASRCSPSATSPVSLSSSSTSGHGSTSDCLFPRRSSASVSGSPSDGGFISSDEYGS 433
            S   P +R    + +P ++   S S        L PR+ S S                  
Sbjct: 2008 SRTSPVTRRRSRSRTPPAIRRRSRS-----RTPLLPRKRSRS-----------------R 2045

Query: 434  SPCDFRSSFRSVTPD------SLGHTPPARGEEELSNYICMGGKGPSTLTAPNGHYILSR 487
            SP   R   RS TP       SL  +PPA      S        G S+  + +     +R
Sbjct: 2046 SPLAIRRRSRSRTPRTARGKRSLTRSPPAIRRRSAS--------GSSSDRSRSATPPATR 2097

Query: 488  GGNGHRCTPGTGLGTSPALAGDEAASAADLDNRFRKRTHSAGTSPTITHQKTPSQSSVAS 547
              +G R  P     +  +     + S   LD     R  S G    +   +TP       
Sbjct: 2098 NHSGSRTPPVALNSSRMSCFSRPSMSPTPLD-----RCRSPGMLEPLGSSRTP------- 2145

Query: 548  IEEYTEMMPAYPPGGGS-----GGRLPGHRHSAFVPTRSYPEEGLEMHPLERRGGHHRPD 602
                   M      GGS     G R+P H+ +      S PE             +H   
Sbjct: 2146 -------MSVLQQAGGSMMDGPGPRIPDHQRT------SVPE-------------NHAQS 2179

Query: 603  SSTLHTDDGYMPMSPGVAPVPSGRKGSGDYMPMSPKSVSAPQQIIN--PIRRHPQRVDPN 660
               L        +S G A  P     +G    MS      P   +   P      R+   
Sbjct: 2180 RIAL----ALTAISLGTARPPPSMSAAGLAARMSQVPAPVPLMSLRTAPAANLASRIPAA 2235

Query: 661  GYMMMSPSGGCSPDIGGGPSSSSSSSNAVPSGTSYGKLWTNGVGGHHSHVLPH-PKPPVE 719
                M+ +   +P I    + + S + A  +  +     T       +   P  P  P  
Sbjct: 2236 SAAAMNLASARTPAIPTAVNLADSRTPAAAAAMNLASPRTAVAPSAVNLADPRTPTAPAV 2295

Query: 720  SSGGKLLPCTGDYMNMSPVGDSNTSSPSDCYYGPEDPQHKPVLSYYSLPRSFKHTQRPGE 779
            +  G   P     ++++  G   T++                    + P S +  Q P  
Sbjct: 2296 NLAGARTPAALAALSLTGSGTPPTAA--------------------NYPSSSRTPQAPAS 2335

Query: 780  PE-EGARHQHLRLSTS-SGRLLYAATADDSSSSTSSDSLGGGYCGARL-EPSLPHPHHQV 836
                G R  H     + +G    AA A    +S +S  +     GA L  P +P   ++ 
Sbjct: 2336 ANLVGPRSAHATAPVNIAGSRTAAALAP---ASLTSARMAPALSGANLTSPRVPLSAYER 2392

Query: 837  LQPHLPRKVDTAAQTNSRLARPTRLSLGDPKASTLPRAREQQQQQQPLLHPPEPKSPGEY 896
            +       +   A++ +  + P++  +   +A + P +R  Q   Q LL PP    P   
Sbjct: 2393 VSGRTSPPLLDRARSRTPPSAPSQSRMTSERAPS-PSSRMGQAPSQSLL-PPAQDQPRSP 2450

Query: 897  VNIEFGSDQSGYLSGPVAFHSSPSVRCPSQLQPAPREEETGTEEYMKMDLGPGRRAAWQE 956
            V   F SDQS  L               +Q  P    +           L  G  A    
Sbjct: 2451 VPSAF-SDQSRCLI--------------AQTTPVAGSQS----------LSSGAVATTTS 2485

Query: 957  STGVEMGRLGPAPPGAASICRPTRAVPSSRGDYMTMQMSCPRQSYVDTSPAAPVSYADMR 1016
            S G   G L    PG          VP S        +  P  S   T    P + A ++
Sbjct: 2486 SAGDHNGMLSVPAPG----------VPHS-------DVGEPPAS---TGAQQPSALAALQ 2525

Query: 1017 TGIAAEEVSLPRATMAAASSSSAASASPTGPQGAAELAAHSSLLGGPQGPGGMSAFTRV- 1075
                    S   ++ +++SSSS++S+S +    ++  +  SSL   P+      A  RV 
Sbjct: 2526 PAKERRSSSSSSSSSSSSSSSSSSSSSSSSSGSSSSDSEGSSLPVQPE-----VALKRVP 2580

Query: 1076 NLSPNRNQSAKVIRAD---PQGCRRRHSSETFSSTPSATRVGNTVPFGAGAAVGGGGGSS 1132
            + +P   ++ +  R     P   +RR SS + SS+ S++         + ++      SS
Sbjct: 2581 SPTPAPKEAVREGRPPEPTPAKRKRRSSSSSSSSSSSSSS-------SSSSSSSSSSSSS 2633

Query: 1133 SSSEDVKRHSSASFENVWLRPGELGGAPKEPAKLCGAAGGLENGLNYIDLDLVKDFKQCP 1192
            SSS      SS+S      +PG     PK  +      G   +      +D ++D +   
Sbjct: 2634 SSSSSSSSSSSSSSSPSPAKPGP-QALPKPASPKKPPPGERRSRSPRKPIDSLRDSRSLS 2692

Query: 1193 QECTPEPQPPPPPPPHQPLGSGESSSTRR 1221
                   +P P P P     S     +RR
Sbjct: 2693 YSPVERRRPSPQPSPRDQQSSSSERGSRR 2721



 Score = 40.8 bits (94), Expect = 0.008
 Identities = 64/270 (23%), Positives = 92/270 (34%), Gaps = 50/270 (18%)

Query: 964  RLGPAPPGAASICRPTRAVPSSRGDYMTMQMSCPRQSYVDTSPAAPVSYADMRTGIAAEE 1023
            R  P+ P  + +       PSSR      Q   P       SP  P +++D    + A+ 
Sbjct: 2408 RTPPSAPSQSRMTSERAPSPSSRMGQAPSQSLLPPAQDQPRSPV-PSAFSDQSRCLIAQ- 2465

Query: 1024 VSLPRATMAAASSSSAASASPTGPQGAAELAAHSSLLGGPQGPGGMSAFTRVNLSPNRNQ 1083
                  T  A S S ++ A  T    A +   H+ +L  P      S       S    Q
Sbjct: 2466 -----TTPVAGSQSLSSGAVATTTSSAGD---HNGMLSVPAPGVPHSDVGEPPASTGAQQ 2517

Query: 1084 SAKVIRADPQGCRRRHSSETFSSTPSATRVGNTVPFGAGAAVGGGGGSSSSSEDVKRHSS 1143
             + +    P   RR  SS + SS+ S++                   SSSSS      SS
Sbjct: 2518 PSALAALQPAKERRSSSSSSSSSSSSSS------------------SSSSSSSSSSSGSS 2559

Query: 1144 ASFENVWLRPGELGGAPKEPAKLCGAAGGLENGLNYIDLDLVKDFKQCPQECTPEPQPPP 1203
            +S         E    P +P                + L  V      P+E   E +PP 
Sbjct: 2560 SS-------DSEGSSLPVQPE---------------VALKRVPSPTPAPKEAVREGRPPE 2597

Query: 1204 PPPPHQPLGSGESSSTRRSSEDLSAYASIS 1233
            P P  +   S  SSS+  SS   S+ +S S
Sbjct: 2598 PTPAKRKRRSSSSSSSSSSSSSSSSSSSSS 2627



 Score = 40.0 bits (92), Expect = 0.014
 Identities = 60/291 (20%), Positives = 99/291 (34%), Gaps = 41/291 (14%)

Query: 265 RPRSKSQSSSNCSNPISVPLRRHHLNNPPPSQVGLTRRSRTESITATSPASMVGGKPGSF 324
           + + K +  S  + P     R H   +   +    T RSR+ S  A +  + + G+  S 
Sbjct: 239 KSKDKKRKRSRSTTPAPKSRRAHRSTSADSASSSDTSRSRSRSAAAKTHTTALAGRSPSP 298

Query: 325 RVRASSDGEGTMSRPASVD-----------GSPVSPSTNRTHAHRHRGSARLHPPLNHSR 373
                 +G+   S P +               P SP  ++    + + + R  P    S 
Sbjct: 299 ASGRRGEGDAPFSEPGTTSTQRPSSPETATKQPSSPYEDKDKDKKEKSATRPSPSPERSS 358

Query: 374 SIPMPASRC-----------SPSATSPVSLSSSSTSGHGSTSDCLFPRRSSASVSGSPSD 422
           + P P +              P AT+P+S    +     S +    P +S   +  S   
Sbjct: 359 TGPEPPAPTPLLAERHGGSPQPLATTPLSQEPVNPPSEASPTRDRSPPKSPEKLPQSS-- 416

Query: 423 GGFISSDEYGSSPCDFR-SSFRSVTPDSLGHTPPARGEEELSNYICMGGKGPSTLTAPNG 481
               SS+    SP   + S   S +P+S    P      E+S          S+ T+ N 
Sbjct: 417 ----SSESSPPSPQPTKVSRHASSSPESPKPAPAPGSHREIS----------SSPTSKNR 462

Query: 482 HYILSRGGNGHRCTPGTGLGTSPALAGDEAASAADLDNRFRKRTHSAGTSP 532
            +  ++    H  TP   +G S + A   A           KR HS   SP
Sbjct: 463 SHGRAKRDKSHSHTPSRRMGRSRSPA--TAKRGRSRSRTPTKRGHSRSRSP 511



 Score = 37.4 bits (85), Expect = 0.090
 Identities = 60/264 (22%), Positives = 87/264 (32%), Gaps = 37/264 (14%)

Query: 618 GVAPVP-SGRKGSGDYMPMSPKSVSAPQQIINPIRRHPQRVDPNGYMMMSPSGGCSPDIG 676
           G +P P SGR+G GD  P S    ++ Q+  +P     Q   P  Y              
Sbjct: 293 GRSPSPASGRRGEGD-APFSEPGTTSTQRPSSPETATKQPSSP--YEDKDKDKKEKSATR 349

Query: 677 GGPSSSSSSSNAVPSGTSYGKLWTNGVGGHHSHVLPHPKPPV-ESSGGKLLPCTGDYMNM 735
             PS   SS+   P                     P P P + E  GG   P     ++ 
Sbjct: 350 PSPSPERSSTGPEP---------------------PAPTPLLAERHGGSPQPLATTPLSQ 388

Query: 736 SPVGDSNTSSPSDCYYGPEDPQHKPVLSYYSLPRSFKHTQRPGEPEEGARHQHLRLSTSS 795
            PV   + +SP+     P+ P+         LP+S      P  P+     +H   S  S
Sbjct: 389 EPVNPPSEASPTRDRSPPKSPE--------KLPQSSSSESSPPSPQPTKVSRHASSSPES 440

Query: 796 GRLLYAATADDSSSSTSSDSLGGGYCGARLEPSLPHPHHQVLQPHLPRKVDTAAQTNSRL 855
            +    A A  S    SS          R +    H H    +    R   TA +  SR 
Sbjct: 441 PK---PAPAPGSHREISSSPTSKNRSHGRAKRDKSHSHTPSRRMGRSRSPATAKRGRSRS 497

Query: 856 ARPTRLSLGDPKASTLPRAREQQQ 879
             PT+      ++    R+R  Q+
Sbjct: 498 RTPTKRGHSRSRSPQWRRSRSAQR 521



 Score = 36.6 bits (83), Expect = 0.15
 Identities = 52/179 (29%), Positives = 66/179 (36%), Gaps = 31/179 (17%)

Query: 267  RSKSQSSSNCSNPISVPLRRHHLNNPPPSQVGLTRRSRTESITATSP------------- 313
            RS+S SS +       PLR+   +   P     +R S   S + +SP             
Sbjct: 1556 RSESDSSPDSKAKTRTPLRQRSRSGSSPEVDSKSRLSPRRSRSGSSPEVKDKPRAAPRAQ 1615

Query: 314  ----------ASMVGGKPGSFRVRASSDGEG-TMSRPASVDGSPVSPSTNRTHAHRHRGS 362
                      A      P   R  +SS G G +    +S + SP  P  +RT     RGS
Sbjct: 1616 SGSDSSPEPKAPAPRALPRRSRSGSSSKGRGPSPEGSSSTESSPEHPPKSRT---ARRGS 1672

Query: 363  ARLHPPLNHSRSIP-MPASRCSPSATSPVSLS--SSSTSGHGSTSDCLFPR-RSSASVS 417
                 P   SR+ P   +SR SP  T    LS  S S S    T     PR R S SVS
Sbjct: 1673 RSSPEPKTKSRTPPRRRSSRSSPELTRKARLSRRSRSASSSPETRSRTPPRHRRSPSVS 1731



 Score = 36.6 bits (83), Expect = 0.15
 Identities = 47/162 (29%), Positives = 64/162 (39%), Gaps = 18/162 (11%)

Query: 266  PRSKSQSSS---NCSNPISVPLRRHHLNNPPPSQVGLTR---RSRTESITATSPASMVGG 319
            P  KS+SS    + S+P +    R    +P P   GL R   RSR E    T      G 
Sbjct: 1735 PAEKSRSSRRRRSASSPRTKTTSRRG-RSPSPKPRGLQRSRSRSRREKTRTTRRRDRSGS 1793

Query: 320  KPGSFRVRASSDGEGTMSRPASVDG-----SPVSPSTNRTHAHRHRGSARLHPPLNHSRS 374
               + R R  S     ++R           SP    ++RT + R RG +R  PP +  RS
Sbjct: 1794 SQSTSRRRQRSRSRSRVTRRRRGGSGYHSRSPARQESSRTSSRRRRGRSRT-PPTSRKRS 1852

Query: 375  IPMPASRCSPSA-TSPVSLSSSSTSGHGSTSDCLFPRRSSAS 415
                 SR SP+      S +S +T     +   L  RR S S
Sbjct: 1853 ----RSRTSPAPWKRSRSRASPATHRRSRSRTPLISRRRSRS 1890



 Score = 30.8 bits (68), Expect = 8.4
 Identities = 50/193 (25%), Positives = 68/193 (35%), Gaps = 38/193 (19%)

Query: 265  RPRSKSQSSSNCSNPISVPLRRHHLNNPPPSQVGLTRRSRTESITATSP---ASMVGGKP 321
            R RS+S SS    +   +  RR    + P  +       R +S + +SP   A      P
Sbjct: 1574 RQRSRSGSSPEVDSKSRLSPRRSRSGSSPEVKDKPRAAPRAQSGSDSSPEPKAPAPRALP 1633

Query: 322  GSFRVRASSDGEGTMSR-PASVDGSPVSPSTNRTHAHRHRGS------ARLHPPLNHSRS 374
               R  +SS G G      +S + SP  P  +RT     R S      +R  P    SRS
Sbjct: 1634 RRSRSGSSSKGRGPSPEGSSSTESSPEHPPKSRTARRGSRSSPEPKTKSRTPPRRRSSRS 1693

Query: 375  IPM-------------------------PASRCSPSATSPVSLSSSSTSGHGSTSDCLFP 409
             P                          P  R SPS +SP     S +S    ++    P
Sbjct: 1694 SPELTRKARLSRRSRSASSSPETRSRTPPRHRRSPSVSSPEPAEKSRSSRRRRSASS--P 1751

Query: 410  RRSSASVSG-SPS 421
            R  + S  G SPS
Sbjct: 1752 RTKTTSRRGRSPS 1764


>gi|18105042 GRB2-associated binding protein 2 isoform a [Homo
           sapiens]
          Length = 676

 Score = 51.2 bits (121), Expect = 6e-06
 Identities = 37/140 (26%), Positives = 66/140 (47%), Gaps = 20/140 (14%)

Query: 9   GFSDVRKVGYLRKPK--------SMHKRFFVLRAASEAGGPARLEYYENEKKWRHKSSAP 60
           G  DV   G+LRK          +  KR+F+LR+   +G P  LEYY+N+      S  P
Sbjct: 3   GGGDVVCTGWLRKSPPEKKLRRYAWKKRWFILRSGRMSGDPDVLEYYKND-----HSKKP 57

Query: 61  KRSIPLESCFNIN-----KRADSKNKHLVALYTRDEHFAIAADSEAEQDSWYQALLQL-- 113
            R I L  C  ++      + + ++  +  + T +  F + A++E + + W Q++ Q+  
Sbjct: 58  LRIINLNFCEQVDAGLTFNKKELQDSFVFDIKTSERTFYLVAETEEDMNKWVQSICQICG 117

Query: 114 HNRAKGHHDGAAALGAGGGG 133
            N+A+   D    + + G G
Sbjct: 118 FNQAEESTDSLRNVSSAGHG 137



 Score = 32.0 bits (71), Expect = 3.8
 Identities = 20/63 (31%), Positives = 32/63 (50%), Gaps = 10/63 (15%)

Query: 603 SSTLHTDDGYMPMSPG----VAPVPSGRKGSGDYMPMSP-----KSVSAPQQIINPIRRH 653
           S + +++D Y+PM+PG    +A   +G      Y+PMSP      S+  P   + P+ R 
Sbjct: 443 SDSTNSEDNYVPMNPGSSTLLAMERAGDNSQSVYIPMSPGAHHFDSLGYPSTTL-PVHRG 501

Query: 654 PQR 656
           P R
Sbjct: 502 PSR 504


>gi|169658378 trinucleotide repeat containing 18 [Homo sapiens]
          Length = 2968

 Score = 50.8 bits (120), Expect = 8e-06
 Identities = 64/286 (22%), Positives = 107/286 (37%), Gaps = 23/286 (8%)

Query: 930  APREEETGTEEYMKMDLGPGRRAAWQESTGVEMGRLGPAPPGAASICRPTRAVPSSRGDY 989
            +P+ ++      ++ D G G    WQE   +    LG  PP A S   P    P +    
Sbjct: 2471 SPKSKKAKEALLLREDPGAG---GWQEPKSLLS--LGSYPPAAGS-SEPKAPWPKATDGD 2524

Query: 990  MTMQMSCPRQSYVDTSPAAPVSYADMRTGIAAEEVSLPRATMAAASSSSAASASPTGPQG 1049
            +  +   P  ++ D+        A      A E  S   ++  ++SSSS++S+S +  +G
Sbjct: 2525 LAQEPG-PGLTFEDSGNPKSPDKAQAEQDGAEESESSSSSSSGSSSSSSSSSSSGSETEG 2583

Query: 1050 AAELAAHSSLLGGPQGPGGMSAFTRVNLSPNRNQSAKVIRADPQGCRRRHSSETFSSTPS 1109
              E   +     G  G    +A +R     + + S+    +         SS + SS+ S
Sbjct: 2584 EEEGDKNGDGGCGTGGRNCSAASSRAASPASSSSSSSSSSSSSSSSSSSSSSSSSSSSSS 2643

Query: 1110 ATRVGNTVPFGAGAAVGGGGGSSSSSEDVKRHSSASFENVWLRPGELGGAPKE---PAKL 1166
            ++   ++    + ++      SSSSS       S+   +    P    G   +   P K 
Sbjct: 2644 SSSSSSSSSSSSSSSSSSSSSSSSSSSSTTDEDSSCSSDDEAAPAPTAGPSAQAALPTKA 2703

Query: 1167 CGAAGGLENGLNYIDLDLVKDFKQCPQECTPEPQP-PPPPPPHQPL 1211
               AG              +     P + TP PQP  PPP P QPL
Sbjct: 2704 TKQAGK------------ARPSAHSPGKKTPAPQPQAPPPQPTQPL 2737



 Score = 37.4 bits (85), Expect = 0.090
 Identities = 42/168 (25%), Positives = 57/168 (33%), Gaps = 15/168 (8%)

Query: 291  NPPPSQVGLTRRSRTESITATSPASMVGGKPGSFRVRASSDGEGTMSRPASVDGSPVSPS 350
            NP         +   E   ++S +S       S    + S+ EG      + DG   +  
Sbjct: 2540 NPKSPDKAQAEQDGAEESESSSSSSSGSSSSSSSSSSSGSETEGEEEGDKNGDGGCGTGG 2599

Query: 351  TNRTHAHRHRGSARLHPPLNHSRSIPMPASRCSPSATSPVSLSSSSTSGHGSTSDCLFPR 410
             N + A     S               PAS  S S++S  S SSSS+S   S+S      
Sbjct: 2600 RNCSAASSRAAS---------------PASSSSSSSSSSSSSSSSSSSSSSSSSSSSSSS 2644

Query: 411  RSSASVSGSPSDGGFISSDEYGSSPCDFRSSFRSVTPDSLGHTPPARG 458
             SS+S S S S     SS    SS         S + D      P  G
Sbjct: 2645 SSSSSSSSSSSSSSSSSSSSSSSSSSSTTDEDSSCSSDDEAAPAPTAG 2692



 Score = 36.6 bits (83), Expect = 0.15
 Identities = 39/141 (27%), Positives = 54/141 (38%), Gaps = 6/141 (4%)

Query: 325  RVRASSDG-EGTMSRPASVDGSPVSPSTNRTHAHRHRGSARLHPPLNHSRSIPMPASRCS 383
            + +A  DG E + S  +S  GS  S S++ +      G        N           CS
Sbjct: 2546 KAQAEQDGAEESESSSSSSSGSSSSSSSSSSSGSETEGEEE--GDKNGDGGCGTGGRNCS 2603

Query: 384  PS---ATSPVSLSSSSTSGHGSTSDCLFPRRSSASVSGSPSDGGFISSDEYGSSPCDFRS 440
             +   A SP S SSSS+S   S+S       SS+S S S S     SS    SS     S
Sbjct: 2604 AASSRAASPASSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSS 2663

Query: 441  SFRSVTPDSLGHTPPARGEEE 461
            S  S +  +         ++E
Sbjct: 2664 SSSSSSSSTTDEDSSCSSDDE 2684



 Score = 34.7 bits (78), Expect = 0.58
 Identities = 119/559 (21%), Positives = 171/559 (30%), Gaps = 124/559 (22%)

Query: 368  PLNHSRSIPMPASRCSPSATSPVSLSSSSTSGHGSTSDCLFPRRSSASVSGSPSDGGFIS 427
            PL+H R +P P  +   +  SP  L  S+      TS            +G   DGG   
Sbjct: 2273 PLSHIRLLP-PDYKIQCAEPSPALLVPSAKRRSRKTS----------KDTGEGKDGGTAG 2321

Query: 428  SDEYGSSPCDFRSSFRSVTPDSLGHTPPARGEEELSNYICMGGKGPSTLTAPNGHYILSR 487
            S+E G+                      ARG           G+ PS     +    L  
Sbjct: 2322 SEEPGAK---------------------ARGR----------GRKPSAKAKGDRAATLEE 2350

Query: 488  GGNGHRCTPGTGLGTSPALA-GDEAASAADLDNRFRKRTHSAGTSPTITHQKTPSQSSVA 546
            G N     P T L   P+   G + +    +D R   +   A  +P       P+ +S  
Sbjct: 2351 G-NPTDEVPSTPLALEPSSTPGSKKSPPEPVDKR--AKAPKARPAPPQPSPAPPAFTSCP 2407

Query: 547  SIEEYTEM--------------MPAYPP----------GGGSGGRLPGHRHSAFV----- 577
            + E + E+              MPA  P           G  G R PG      V     
Sbjct: 2408 APEPFAELPAPATSLAPAPLITMPATRPKPKKARAAEESGAKGPRRPGEEAELLVKLDHE 2467

Query: 578  ----PTRSYPEEGLEMHPLERRGGHHRPDSSTLHTDDGYMPMSPGVAPVPSGRKGSGDYM 633
                P     +E L +      GG   P S  L +   Y P +    P     K +   +
Sbjct: 2468 GVTSPKSKKAKEALLLREDPGAGGWQEPKS--LLSLGSYPPAAGSSEPKAPWPKATDGDL 2525

Query: 634  PMSPKSVSAPQQIINPIRRHPQRVDPNGYMMMSPSGGCSPDIGGGPSSSSSSSNAVPSGT 693
               P      +   NP      + + +G    S S   S       SSSSSSS +   G 
Sbjct: 2526 AQEPGPGLTFEDSGNPKSPDKAQAEQDG-AEESESSSSSSSGSSSSSSSSSSSGSETEGE 2584

Query: 694  SYGKLWTNGVGGHHSHVLPHPKPPVESSGGKLLPCTGDYMNMSPVGDSNTSSPSDCYYGP 753
              G    NG GG               +GG+           SP   S++SS S      
Sbjct: 2585 EEGD--KNGDGGC-------------GTGGRNCSAASSRA-ASPASSSSSSSSSSSSSSS 2628

Query: 754  EDPQHKPVLSYYSLPRSFKHTQRPGEPEEGARHQHLRLSTSSGRLLYAATADDSSSSTSS 813
                     S  S   S   +         +       S+SS     + T +DSS S+  
Sbjct: 2629 SSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSS-----STTDEDSSCSSDD 2683

Query: 814  DSLGGGYCGARLEPSLPHPHHQVLQPHLPRKVDTAAQTNSRLARPTRLSLGDPKASTLPR 873
            ++      G   + +LP                T A   +  ARP+  S G    +  P+
Sbjct: 2684 EAAPAPTAGPSAQAALP----------------TKATKQAGKARPSAHSPGKKTPAPQPQ 2727

Query: 874  AREQQQQQQPLLHPPEPKS 892
            A   Q  Q     P +PK+
Sbjct: 2728 APPPQPTQ-----PLQPKA 2741



 Score = 31.2 bits (69), Expect = 6.4
 Identities = 38/173 (21%), Positives = 65/173 (37%), Gaps = 14/173 (8%)

Query: 260  MSDEFRPRSKSQSSSNCSNPISVPLRRHHLNNPPPSQVGLTRRSRTESITATSPASMVGG 319
            ++ E  P    + S N  +P      +        S    +  S + S +++S +   G 
Sbjct: 2525 LAQEPGPGLTFEDSGNPKSPDKAQAEQDGAEESESSSSSSSGSSSSSSSSSSSGSETEGE 2584

Query: 320  KPGSFRVRASSDGEGTMSR-----------PASVDGSPVSPSTNRTHAHRHRGSARLHPP 368
            + G    +    G GT  R           PAS   S  S S++ + +     S+     
Sbjct: 2585 EEGD---KNGDGGCGTGGRNCSAASSRAASPASSSSSSSSSSSSSSSSSSSSSSSSSSSS 2641

Query: 369  LNHSRSIPMPASRCSPSATSPVSLSSSSTSGHGSTSDCLFPRRSSASVSGSPS 421
             + S S    +S  S S++S  S SSSS+S     S C     ++ + +  PS
Sbjct: 2642 SSSSSSSSSSSSSSSSSSSSSSSSSSSSSSTTDEDSSCSSDDEAAPAPTAGPS 2694


>gi|20070302 docking protein 4 [Homo sapiens]
          Length = 326

 Score = 50.1 bits (118), Expect = 1e-05
 Identities = 58/255 (22%), Positives = 98/255 (38%), Gaps = 41/255 (16%)

Query: 10  FSDVRKVGYLR---KPKSMHKRFFVLRAASEAGGPARLEYYENEKKWRHKSSAPKRSIPL 66
           FSD+ K GY++   +   +++R +++   S + GP RLE Y +EK    +       I  
Sbjct: 5   FSDIVKQGYVKMKSRKLGIYRRCWLVFRKSSSKGPQRLEKYPDEKSVCLRGCPKVTEISN 64

Query: 67  ESCFNINKRADSKNKHLVALYTRDEHFAIAADSEAEQDSWYQALLQLHNRAKGHHDGAAA 126
             C     + ++K + +  ++T D       DSE E + WY+ L                
Sbjct: 65  VKCVTRLPK-ETKRQAVAIIFTDDSARTFTCDSELEAEEWYKTL---------------- 107

Query: 127 LGAGGGGGSCSGSSGLGEAGEDLSYGD---VPPGPAFKEV--WQVILKPKGLGQTKNLIG 181
                          LG    D+S G+   + PG   ++   + V L P       ++ G
Sbjct: 108 -----------SVECLGSRLNDISLGEPDLLAPGVQCEQTDRFNVFLLP---CPNLDVYG 153

Query: 182 IYRLCLTSKTISFVKL-NSEAAAVVLQLMNIRRCGHSENFFFIEVGRSAVTGPGEFWMQV 240
             +L +T + I    + N     V   L ++RR G     F  E GR    G G +  Q 
Sbjct: 154 ECKLQITHENIYLWDIHNPRVKLVSWPLCSLRRYGRDATRFTFEAGRMCDAGEGLYTFQT 213

Query: 241 DD-SVVAQNMHETIL 254
            +   + Q +H   L
Sbjct: 214 QEGEQIYQRVHSATL 228


>gi|226509740 SR-related CTD-associated factor 1 [Homo sapiens]
          Length = 1312

 Score = 49.7 bits (117), Expect = 2e-05
 Identities = 130/573 (22%), Positives = 186/573 (32%), Gaps = 87/573 (15%)

Query: 669  GGCSPDIGGGPSSSSSSSNAVPSGTSYGKLWTNGVGGHHSHVLPHPKPPVESSGGKLLPC 728
            GG +P     PSS+SSS +  PS +S                 P P PP  +      P 
Sbjct: 182  GGPAPP--PAPSSASSSPSPSPSSSSPS---------------PPPPPPPPAPPAPPAPR 224

Query: 729  TGDYMNMSPVGDSNTSSPS-DCYYGPEDPQHKPVLSYYSL--PRSFKHTQRPGEPEEGAR 785
               Y    P  ++ +  P+ +  Y P +P      S      P   +  +   E EE   
Sbjct: 225  FDIYDPFHPTDEAYSPPPAPEQKYDPFEPTGSNPSSSAGTPSPEEEEEEEEEEEEEEEDE 284

Query: 786  HQHLRLSTSSGRLLYAATADDSSSSTSSDSLGGGYCGARLEPSLPHPHHQVLQPHLPRKV 845
             +   LS S  R+          +S S D  G        +P+ P P      P  P +V
Sbjct: 285  EEEEGLSQSISRISETLAGIYDDNSLSQDFPGDESPRPDAQPTQPTP-----APGTPPQV 339

Query: 846  DTAAQTNSRLAR-----PTRLSLGDPKASTLPRAREQQQQQQPLLHPPEPK-SPGEYVNI 899
            D+     +   R         +  + K S             PLL P + +   GE V  
Sbjct: 340  DSTRADGAMRRRVFVVGTEAEACREGKVSVEVVTAGGAALPPPLLPPGDSEIEEGEIVQP 399

Query: 900  EFGS-------DQSGYLSGPVAFHSSPSVRCPSQLQPAPREEETGTEEYMKMDLGPGRRA 952
            E             G  + P    S+     P    PAPR  E   ++++ +        
Sbjct: 400  EEEPRLALSLFRPGGRAARPTPAASATPTAQPLPQPPAPRAPE--GDDFLSLHAESDGEG 457

Query: 953  AWQESTGVEMGRLGPAPPGAASICRPTRAVPSSRGDYMTMQMSCPRQSYVDTSPA-APVS 1011
            A Q    V++G   PAPP A S           R   +T +    RQ     +PA AP +
Sbjct: 458  ALQ----VDLGEPAPAPPAADS----RWGGLDLRRKILTQRRERYRQRSPSPAPAPAPAA 509

Query: 1012 YADMRT-GIAAEEVSLPRATMAAASSSSAASASPTGPQGAAELAAHSSLLGGPQGPGGMS 1070
             A   T   +  E         AASSSS    +P  P    +   H S     + PG  +
Sbjct: 510  AAGPPTRKKSRRERKRSGEAKEAASSSSGTQPAPPAPASPWDSKKHRS---RDRKPGSHA 566

Query: 1071 AFTRVNLSPNRNQSAKVIRADPQGCRRRHSSETFSSTPSATRVGNTVPFGAGAAVGGGGG 1130
            + +    S +R++S    R      RRR  S    S     R          +A      
Sbjct: 567  SSSARRRSRSRSRSRSTRRRSRSTDRRRGGSRRSRSREKRRR-------RRRSASPPPAT 619

Query: 1131 SSSSSEDVKRHSSASFENVWLRPGELGGAPKEPAKLCGAAGGLENGLNYIDLDLVKDFKQ 1190
            SSSSS   +RH     +         GG  K+  K   + G   +G              
Sbjct: 620  SSSSSSRRERHRGKHRD---------GGGSKKKKKRSRSRGEKRSGDG------------ 658

Query: 1191 CPQECTPEPQPPPPPPPHQPLGSGESSSTRRSS 1223
                   E  P P PPP      G+  S RR +
Sbjct: 659  ------SEKAPAPAPPPSGSTSCGDRDSRRRGA 685



 Score = 30.8 bits (68), Expect = 8.4
 Identities = 43/198 (21%), Positives = 69/198 (34%), Gaps = 22/198 (11%)

Query: 1025 SLPRATMAAASSSSAASASPTGPQGAAELAAHSSLLGGPQGPGGMSAFTRVNLSPNRNQS 1084
            S  R    +   S  A A    P G+       S   G   P           +  R  +
Sbjct: 647  SRSRGEKRSGDGSEKAPAPAPPPSGSTSCGDRDSRRRGAVPPSIQDLTDHDLFAIKRTIT 706

Query: 1085 A-KVIRADPQGCRRRHSSETFSSTPSATRVGNTVPFGAGAAVGGGGGSSSSSEDVKRHSS 1143
              ++ ++DP+G           S   A+     V + +    G   G  SS +D +R  +
Sbjct: 707  VGRLDKSDPRG----------PSPAPASSPKREVLYDSEGLSGEERGGKSSQKDRRRSGA 756

Query: 1144 ASFENVWLRPGELGGAPKEPAKLCGAAGGLENGLNYIDLDLVKDFKQC--PQECTPEPQP 1201
            AS  +          + ++ ++     GG  +     D D  +  K+   P+E  P   P
Sbjct: 757  ASSSS---------SSREKGSRRKALDGGDRDRDRDRDRDRDRSSKKARPPKESAPSSGP 807

Query: 1202 PPPPPPHQPLGSGESSST 1219
            PP PP     GS  SSS+
Sbjct: 808  PPKPPVSSGSGSSSSSSS 825


>gi|239758148 PREDICTED: similar to mucin 11 [Homo sapiens]
          Length = 587

 Score = 49.3 bits (116), Expect = 2e-05
 Identities = 99/434 (22%), Positives = 156/434 (35%), Gaps = 50/434 (11%)

Query: 288 HLNNPPPSQVGLTRRSRTESITATSPASMVG-GKPGSFRVRASSDGEGTMSRPASVDGSP 346
           H +      + L  RS T  +   S  S +  G   +  +  S+   G   +  +   SP
Sbjct: 73  HSSQDATGTIVLPARSTTSVLLGESTTSPISSGSMETTALPGSTTTPGLSEKSTTFHSSP 132

Query: 347 VSPSTNRTHAHRHRGSARLHPPLNHSRSIPMPASRCSPSATSPVSLSSSSTSGH---GST 403
            SP+T  + A             +HSR      +    S T+P  LS  ST+ H   GST
Sbjct: 133 RSPATTLSPASTTSSGVSEESTTSHSRPGSTHTTAFPDSTTTP-GLSRHSTTSHSSPGST 191

Query: 404 SDCLFPRRSSASVSGSPSDGGFISSDEYGSSPCDFRSSFRSVTPDSLGHTPPARGEEELS 463
              L P  +S + SG PS     S    GS+  D   S  S T  S G        +E +
Sbjct: 192 DTTLLP--ASTTTSG-PSQESTTSHSSPGST--DTALSPGSTTALSFG--------QEST 238

Query: 464 NYICMGGKGPSTL----TAPNGHYILSRGGNGHRCTPGTGL----GTSPALAGDEAA--- 512
            +    G   +TL    T  +G    S   +    +P T L     TSP L G+  A   
Sbjct: 239 TFHSSPGSTHTTLFPDSTTSSGIVEASTRVHSSTGSPRTTLSPASSTSPGLQGESTAFQT 298

Query: 513 -SAADLDNRFRKRTHSAGTSPTITHQKTPSQS------SVASIEEYTEMMPAYPPGGGSG 565
             A+         T +A    + T+ ++P  +      + ++   ++E    +     + 
Sbjct: 299 HPASTHTTPSPPSTATAPVEESTTYHRSPGSTPTTHFPASSTTSGHSEKSTIFHSSPDAS 358

Query: 566 GRLPGHRHSAFVPTRSYPEEGLEMHPLERRGGHHR---PDSSTLHTDDGYMPMSPGVAPV 622
           G  P   HS    T    EE    H   + G  H    PDS+T       +   P  +  
Sbjct: 359 GTTPSSAHST---TSGVSEESSTSH--SQPGSTHTTAFPDSTT----TSGLSQEPTTSHS 409

Query: 623 PSG-RKGSGDYMPMSPKSVSAPQQIINPIRRHPQRVDPNGYMMMSPSGGCSPDIGGGPSS 681
             G  + + D  P  P + +AP ++       P       +   S + G S +     SS
Sbjct: 410 SQGSTEATLDTTPSPPGTTAAPVEVSTTYHSRPSSTPTTHFSASSTTLGRSEESTTVHSS 469

Query: 682 -SSSSSNAVPSGTS 694
             S+ + A+P  T+
Sbjct: 470 PGSTETTALPGSTT 483



 Score = 44.7 bits (104), Expect = 6e-04
 Identities = 130/555 (23%), Positives = 191/555 (34%), Gaps = 108/555 (19%)

Query: 383 SPSATSP-VSLSSSSTSGHGSTSDCLFPRRSSASVSGSPSDGGFISSDEYGSSPCDFRSS 441
           +PS TS  V   +S  S  GST+   FP  S+ S     S     S D  G+     RS+
Sbjct: 30  APSTTSALVEEPTSYHSSPGSTATTHFPDSSTTSGRSEESTASHSSQDATGTIVLPARST 89

Query: 442 FRSVTPDSLGHTPPARGEEELSNYICMGGKGPSTLTAPNGHYILSRGGNGHRCTPGTGLG 501
             SV       +P + G  E +         P + T P     LS        +P +   
Sbjct: 90  -TSVLLGESTTSPISSGSMETTAL-------PGSTTTPG----LSEKSTTFHSSPRSPAT 137

Query: 502 T-SPALAGDEAASAADLDNRFRK-RTHSAG-----TSPTITHQKTPSQSSVASIEEYTEM 554
           T SPA       S     +  R   TH+       T+P ++   T S SS  S +  T +
Sbjct: 138 TLSPASTTSSGVSEESTTSHSRPGSTHTTAFPDSTTTPGLSRHSTTSHSSPGSTD--TTL 195

Query: 555 MPAYPPGGG------SGGRLPGHRHSAFVP----TRSYPEEGLEMHPLERRGGHHR---P 601
           +PA     G      +    PG   +A  P      S+ +E    H     G  H    P
Sbjct: 196 LPASTTTSGPSQESTTSHSSPGSTDTALSPGSTTALSFGQESTTFH--SSPGSTHTTLFP 253

Query: 602 DSST----------LHTDDG--YMPMSPGVAPVPSGRKG----------SGDYMPMSPKS 639
           DS+T          +H+  G     +SP  +  P G +G          S    P  P +
Sbjct: 254 DSTTSSGIVEASTRVHSSTGSPRTTLSPASSTSP-GLQGESTAFQTHPASTHTTPSPPST 312

Query: 640 VSAPQQIINPIRRHPQRVDPNGYMMMSPSGG---------CSPDIGG-GPSSSSSSSNAV 689
            +AP +      R P       +   S + G          SPD  G  PSS+ S+++ V
Sbjct: 313 ATAPVEESTTYHRSPGSTPTTHFPASSTTSGHSEKSTIFHSSPDASGTTPSSAHSTTSGV 372

Query: 690 --PSGTSYGKLWTNGVGGHHSHVLPHPKPPVESSGGKLLPCTGDYMNMSPVGDSNTSSPS 747
              S TS+ +      G  H+   P       +SG    P T      S     +T +  
Sbjct: 373 SEESSTSHSQ-----PGSTHTTAFP---DSTTTSGLSQEPTT------SHSSQGSTEATL 418

Query: 748 DCYYGPEDPQHKPV---LSYYSLPRSFKHTQRPGEPEEGARHQHLRLSTSSGRLLYAATA 804
           D    P      PV    +Y+S P S   T                 ST+ GR   + T 
Sbjct: 419 DTTPSPPGTTAAPVEVSTTYHSRPSSTPTTHFSAS------------STTLGRSEESTTV 466

Query: 805 DDSSSSTSSDSLGGGYCGARLEP------SLPHPHHQVLQPHLPRKVDTAAQTNSRLARP 858
             S  ST + +L G    A L        S P      L P        + ++ +  +RP
Sbjct: 467 HSSPGSTETTALPGSTTTAGLSEKSTTFYSSPRSPDTTLSPASTTSSGVSEESTTSHSRP 526

Query: 859 -TRLSLGDPKASTLP 872
            +  +   P ++T+P
Sbjct: 527 GSTHTTAFPGSTTMP 541



 Score = 40.4 bits (93), Expect = 0.011
 Identities = 77/311 (24%), Positives = 117/311 (37%), Gaps = 47/311 (15%)

Query: 294 PSQVGLTRRSRTESI-TATSPASMVG-----------GKPGSFRVRASSDGEGTM----- 336
           PSQ   T  S   S  TA SP S                PGS       D   +      
Sbjct: 205 PSQESTTSHSSPGSTDTALSPGSTTALSFGQESTTFHSSPGSTHTTLFPDSTTSSGIVEA 264

Query: 337 -SRPASVDGSP---VSPSTNRTHAHRHRGSA-RLHPPLNHSRSIPMPASRCSPSATSPVS 391
            +R  S  GSP   +SP+++ +   +   +A + HP   H+   P P S    +AT+PV 
Sbjct: 265 STRVHSSTGSPRTTLSPASSTSPGLQGESTAFQTHPASTHTT--PSPPS----TATAPVE 318

Query: 392 LSSSSTSGHGSTSDCLFPRRSSASVSGSPSDGGFISSDEYGSSPCDFRSSFRSVTPD-SL 450
            S++     GST    FP  S+ S     S     S D  G++P    S+   V+ + S 
Sbjct: 319 ESTTYHRSPGSTPTTHFPASSTTSGHSEKSTIFHSSPDASGTTPSSAHSTTSGVSEESST 378

Query: 451 GHTPPARGEEELSNYICMGGKGPSTLTAPNGHYILSRGGNGHRCTPGTGLGTSPALAGDE 510
            H+ P  G    + +       P + T        +   +    T  T L T+P+  G  
Sbjct: 379 SHSQP--GSTHTTAF-------PDSTTTSGLSQEPTTSHSSQGSTEAT-LDTTPSPPGTT 428

Query: 511 AASAADLDNRFRKRTHSAGTSPTITHQKTPSQSSVASIEEYTEMMPAYPPGGGSGGRLPG 570
           AA            T+ +  S T T   + S +++   EE T +  +  PG      LPG
Sbjct: 429 AAPVE------VSTTYHSRPSSTPTTHFSASSTTLGRSEESTTVHSS--PGSTETTALPG 480

Query: 571 HRHSAFVPTRS 581
              +A +  +S
Sbjct: 481 STTTAGLSEKS 491


>gi|158854042 hypothetical protein LOC222183 [Homo sapiens]
          Length = 653

 Score = 49.3 bits (116), Expect = 2e-05
 Identities = 102/399 (25%), Positives = 135/399 (33%), Gaps = 68/399 (17%)

Query: 265 RPRSKSQSSSNCSNPISVPLRRHHLNNPPPSQVGLTRRSRTESITATSPASMVGGKPGSF 324
           R R K +  S CS   S PLR+          V   RR R++S              GS 
Sbjct: 180 RSRKKRRLESECSCGSSSPLRKKK------KSVKKHRRDRSDS--------------GSR 219

Query: 325 RVRASSDGEGTMSRPASVDGS--PVSPSTNRTHAHRHRGSARLHPPLNHSRSIPMPASRC 382
           R R          R         P + S  R  +HRH   +   P L+   S        
Sbjct: 220 RKRRHRSRSSKCKRKEKNKEKKRPHTESPGR-RSHRHSSGSSHSPSLSSHYS-----DSR 273

Query: 383 SPSATSPVSLSSSSTSGHGSTSDCLFPRRSSASVSGSP--SDGGFISSDEYGS------S 434
           SPS  SP        +G   +S    P  S  S  GSP  + G    S  +G       S
Sbjct: 274 SPSRLSPKHRDEGRKTGSQRSSGSRSPSPSGGSGWGSPQRNGGSGQRSGAHGGRPGSAHS 333

Query: 435 PCDFRSSFRSVTPD---SLGHTPPARGEEELSNYICMGGKGPSTLTAPNGHYILSRGGNG 491
           P D  SS      D   +   TPPARG+E            PS  +AP      S  G G
Sbjct: 334 PPDKPSSPSPRVRDKAAAAAPTPPARGKE-----------SPSPRSAP------SSQGRG 376

Query: 492 HRCTPGTGLGTSPALAGDEAASAADLD-NRFRKRTHSA---GTSPTITHQKTPSQSSVAS 547
            R   G G           + S+A     R R+R   A   G+S +++  ++ S S    
Sbjct: 377 GRAAGGAGRRRRRRRRRRRSRSSASAPRRRGRRRPRPAPPRGSSRSLSRARSSSDSGSGR 436

Query: 548 IEEYTEMMPAYPPGGGSGGRLPGHRHSAFVPTRSYPEEGLEMHPLERRGGHHRPDSSTLH 607
                   P    G G  G+    R     P  + P  G       RRGG   P+  +  
Sbjct: 437 GAPGPGPEPGSERGHGGHGKRAKERPPRARPASTSPSPGAH----GRRGG---PEGKSSS 489

Query: 608 TDDGYMPMSPGVAPVPS-GRKGSGDYMPMSPKSVSAPQQ 645
              G  P S   +  PS  R  S +  P SP    +P++
Sbjct: 490 RSPGPHPRSWSSSRSPSKSRSRSAEKRPHSPSRSPSPKK 528



 Score = 32.3 bits (72), Expect = 2.9
 Identities = 52/182 (28%), Positives = 68/182 (37%), Gaps = 34/182 (18%)

Query: 266 PRSKSQSSSNCSNPISVPLRRHHLNNPPPSQV-GLTRRSRTESITATSPASMVGGKPGSF 324
           P  KS S S   +P S    R    +P  S+     +R  + S + +    +   K G  
Sbjct: 483 PEGKSSSRSPGPHPRSWSSSR----SPSKSRSRSAEKRPHSPSRSPSPKKPLSRDKDGEG 538

Query: 325 RVRASSDGEGTMSRPASVDGSPVSPSTNRTHAHRHRGSARLHPP--LNHSRSIPMPASRC 382
           R R  S+ E T +R  S   SP+          R R S     P  +  +R  P+P  R 
Sbjct: 539 RAR-HSEAEATRARRRSRSYSPIRK--------RRRDSPSFMEPRRITSARKRPIPYYRP 589

Query: 383 SPSATSPVSLSSSSTSGHGSTSDCLFPRRSSASVSGSPSDGGFISSDEYGSSPCDFRSSF 442
           SPS                S+S CL    S+ S S SPS G   S   Y S     RS  
Sbjct: 590 SPS----------------SSSSCLSSDYSTRSHSRSPSPGH--SHGSYSSRSHGTRSRT 631

Query: 443 RS 444
           RS
Sbjct: 632 RS 633


>gi|163965366 nascent polypeptide-associated complex alpha subunit
            isoform a [Homo sapiens]
          Length = 2078

 Score = 49.3 bits (116), Expect = 2e-05
 Identities = 168/752 (22%), Positives = 239/752 (31%), Gaps = 96/752 (12%)

Query: 334  GTMSRPASVDGSPVSPSTNRTHAHRHRGSARLHPPLNHSRSIPMPASRCSPSATSPVSLS 393
            G +S P S    PV  S    ++   +GS +  P   HS + P P    +PSA +P+S  
Sbjct: 822  GNLSSPVS----PVEASFLPENSLSFQGS-KDSPATTHSPTPPSPKGAPTPSAVTPLSPK 876

Query: 394  S----SSTSGHGSTSDCLFPRRSSASVSGSPSDGGFISSDEYGSSPCDFRSSFRSVTPDS 449
                    +   S  +  FP+   A+ +   +    ++S    SSP   R+   +  P  
Sbjct: 877  GVTLPPKETPTPSVVNLPFPKEGPATPAPKQAPALSMTS----SSPKKARA---TPAPKG 929

Query: 450  LGHTPPARGEEELSNYICMGGKG----PSTLTAPNGHYILSRGGNGHRCTPG-TGLGTSP 504
            +  +P  +G            KG    PS   AP           G   TP   G  T P
Sbjct: 930  IPASPSPKGAPTPPAATPPSPKGGPATPSPKWAPTPPAATPPSPKGGPATPSPKGAPTPP 989

Query: 505  ALAGDEAASAADLDNRFRKRTHSAGTSPTITHQKTPSQSSVASIEEYTEMMPAYPPGG-- 562
            A     A   +            A T P +T        +     +     PA  P    
Sbjct: 990  A-----ATPPSPKGGPATPSPKGAPTPPAVTPPSPKGSPAATPFPKGASTPPAATPPSPK 1044

Query: 563  GSGGRLPGHRHSAFVPTRSYPEEGLEMHPLERRGGHHRPDSSTLHTDDGYMPMSPGVAPV 622
            GS    P  + +   P  + P           +GG   P      T     P SP   P 
Sbjct: 1045 GSPAATPLPKGAPTTPAATLPSP---------KGGPATPSLKGAPTPPAATPPSPKGGPA 1095

Query: 623  PSGRKGSGDYMPMSPKSVSAPQQIINPIRRHPQRVDPN--GYMMMSPSGG-CSPDIGGGP 679
                KG+    PM P   + P      +   P +  P        SP GG  +P   G P
Sbjct: 1096 TPSPKGA----PMPP--AATPPSPKGGLATPPHKGAPTTPAATPPSPKGGLATPPPKGAP 1149

Query: 680  SSSSSSSNAVPSGTSYGKLWTNGVGGHHSHVLPHPKPPVESSGGKLLPCTGDYMNMSPVG 739
            ++ +++  +   G +       G     +   P PK  + +   K  P T      SP G
Sbjct: 1150 TTPAATPPSPKGGLATPP--PKGAPTTPAATPPSPKGGLATPSPKGAPTTPAATPPSPKG 1207

Query: 740  DSNTSSPSDCYYGPEDPQHKPVLSYYSLPRSFKHTQRP-GEPEEGARHQHLRLSTSSGRL 798
               T SP      P  P   P       P+    T  P G P   A       S   G  
Sbjct: 1208 GLATPSPKG---APTTPAATP-----PSPKGGLATPSPKGAPTTPAATPP---SPKGGPA 1256

Query: 799  LYAATADDSSSSTSSDSLGGGYCGARLEPSLPHPHHQVLQPHLPRKVDTAAQTNSRLARP 858
                    +  + +  SL GG       P    P+  V+ P  P K   A         P
Sbjct: 1257 TPPPKGAPTPPAATPPSLKGGLA---TPPHKGAPNPAVVTPPSP-KGGPATSPPKGAPTP 1312

Query: 859  TRLSLGDPKAS--TLPRAREQQQQQQPLLHPPEPKS----PGEYVNIEFGSDQSGYLSGP 912
               +   PK S  T P    +     P + PP PK     P    + + G        GP
Sbjct: 1313 PAATPPSPKGSPGTPP---PKGAPTPPAVTPPSPKGTPTLPATTPSSKGGPTTPSSKEGP 1369

Query: 913  VAFHSSPSVR-CPSQLQPAPREEETGTEEYMKMDLGPGRRAAWQESTGVEMGRLGPAPPG 971
                ++PS +  P+   P+P+              GP   +   + T   +  L P    
Sbjct: 1370 TPPAATPSHKGGPAMTPPSPKR-------------GPAIPSPKGDPTSPAVIPLSPKKAP 1416

Query: 972  AASICRPTRAVPSSRGDYMTMQMS------CPRQSYVDTSPAAPVSYAD-MRTGIAAEEV 1024
            A  + R   A P S+GD     ++       P  S     PA P S  D     +     
Sbjct: 1417 ATPVTREGAATP-SKGDLTPPAVTPVSLKKAPATSAPKGGPATPSSKGDPTLPAVTPPSP 1475

Query: 1025 SLPRATMAAASSSSAASASPT-GPQGAAELAA 1055
              P A    A+SSS   A  T  P GA  L A
Sbjct: 1476 KEPPAPKQVATSSSPKKAPATPAPMGAPTLPA 1507



 Score = 42.4 bits (98), Expect = 0.003
 Identities = 166/807 (20%), Positives = 235/807 (29%), Gaps = 136/807 (16%)

Query: 310  ATSPASMVGGKPGSFRVRASSDGEGTMSRPASVDGSPVSPSTNRTHAHRHRGSARLHPPL 369
            A +P S  GG        A+   +G    PA+   SP        H       A   P  
Sbjct: 1084 AATPPSPKGGP-------ATPSPKGAPMPPAATPPSPKGGLATPPHKGAPTTPAATPPSP 1136

Query: 370  NHSRSIPMP-ASRCSPSATSPV---SLSSSSTSGHGSTSDCLFPRRSSASVSGSPSDGGF 425
                + P P  +  +P+AT P     L++    G  +T     P       + SP     
Sbjct: 1137 KGGLATPPPKGAPTTPAATPPSPKGGLATPPPKGAPTTPAATPPSPKGGLATPSPKGAPT 1196

Query: 426  ISSDEYGSSPCDFRSSFRSVTPDSLGHTPPARGEEELSNYICMGGKGPSTLTA-----PN 480
              +    ++P   +    + +P     TP A              KG  T  A     P 
Sbjct: 1197 TPA----ATPPSPKGGLATPSPKGAPTTPAATPPSPKGGLATPSPKGAPTTPAATPPSPK 1252

Query: 481  GHYILSRGGNGHRCTPGTGLGTSPALAGDEAASAADLDNRFRKRTHSAGTSPTITHQKTP 540
            G         G    P  G  T PA      A+   L        H    +P +    +P
Sbjct: 1253 G---------GPATPPPKGAPTPPA------ATPPSLKGGLATPPHKGAPNPAVVTPPSP 1297

Query: 541  SQSSVASIEEYTEMMPAYPPGG--GSGGRLP---GHRHSAFVPTRSYPEEGLEMHPLERR 595
                  S  +     PA  P    GS G  P        A  P        L       +
Sbjct: 1298 KGGPATSPPKGAPTPPAATPPSPKGSPGTPPPKGAPTPPAVTPPSPKGTPTLPATTPSSK 1357

Query: 596  GGHHRPDSSTLHTDDGYMPMSPG-------------VAPVPSGRKGSGDYMPMSPKSVSA 642
            GG   P S    T     P   G               P P G   S   +P+SPK   A
Sbjct: 1358 GGPTTPSSKEGPTPPAATPSHKGGPAMTPPSPKRGPAIPSPKGDPTSPAVIPLSPKKAPA 1417

Query: 643  PQQIINPIRRHPQRVDPNGYMMMSPSGGCSPDIGGGPSSSSSSSN-AVPSGTSYGKLWTN 701
                  P+ R        G +  +P       +   P++S+     A PS  S G     
Sbjct: 1418 -----TPVTREGAATPSKGDL--TPPAVTPVSLKKAPATSAPKGGPATPS--SKGDPTLP 1468

Query: 702  GVGGHHSHVLPHPKPPVESSGGKLLPCTGDYMNMSPVGDSNTSSPSDCYYGPEDPQHKPV 761
             V        P PK    SS  K  P T   M    +     SSP +    P   +    
Sbjct: 1469 AVTPPSPKEPPAPKQVATSSSPKKAPATPAPMGAPTLPAVIPSSPKEVPATPSSRRDPIA 1528

Query: 762  LSYYSLPRSFKHTQRPGEPEEGARHQHLRLSTSSGRLLYAATADDSSSSTSSDSLGGGYC 821
             +   L +    T  P E                  L+  A    S   T          
Sbjct: 1529 PTATLLSKKTPATLAPKEA-----------------LIPPAMTVPSPKKT---------- 1561

Query: 822  GARLEPSLPHPHHQVLQPHLPRKVDTAAQTNSRL-ARPTRLSLGDPKASTLPRAREQQQQ 880
                 P++P P      P         A T S     P+   L  P A T P  +E    
Sbjct: 1562 -----PAIPTPKEAPATPSSKEASSPPAVTPSTYKGAPSPKELLIPPAVTSPSPKEAPTP 1616

Query: 881  QQPLLHPPEPKSPGEYVNIEFGSDQSGYLSGPVAFHSSPSVRCPSQLQPAPREEETGTEE 940
              P + PP P             ++      P    +SP V  PS L+ +P    + T  
Sbjct: 1617 --PAVTPPSP-------------EKGPATPAPKGTPTSPPVT-PSSLKDSPTSPASVT-- 1658

Query: 941  YMKMDLGPGRRA----AWQESTGVEMGRLGPAPPGAASICRPTRAVPSSRGDYMTMQMSC 996
              KM     + +    A +  T ++   + PAP     I  PTR  P ++    T    C
Sbjct: 1659 -CKMGATVPQASKGLPAKKGPTALKEVLVAPAPESTPIITAPTRKGPQTKKSSATSPPIC 1717

Query: 997  PRQ----------SYVDTSPAAPVSYADMRTGIAAEEVSLPRATMAAASSSSAASASPTG 1046
            P            S V  +P  PV     +T    +    P+  +A   S ++   +   
Sbjct: 1718 PDPSAKNGSKGPLSTVAPAPLLPVQKDSSKTAKGKDASHSPKGPLAPPESKASTPLTAAA 1777

Query: 1047 -------PQGAAELAAHSSLLGGPQGP 1066
                   P+ A+  AA S  +  P  P
Sbjct: 1778 FEKVLPKPESASVSAAPSPPVSLPLAP 1804


>gi|239752490 PREDICTED: similar to Mucin-12 [Homo sapiens]
          Length = 456

 Score = 48.9 bits (115), Expect = 3e-05
 Identities = 97/406 (23%), Positives = 147/406 (36%), Gaps = 51/406 (12%)

Query: 298 GLTRRSRTESITATSPASMVGGKPGSFRVRASSDGEGTM-SRPASVDGSPVSPSTNRTHA 356
           GL+ +S T   +  SPA+ +   P S      S+   T  SRP S   +    ST     
Sbjct: 14  GLSEKSTTFHSSPRSPATTLS--PASTTSSGVSEESTTSHSRPGSTHTTAFPDSTTTPGL 71

Query: 357 HRHRGSARLHPPLNHSRSIPMPASRCSPSATSPVSLSSSSTSGHGSTSDCLFPRRSSASV 416
            RH  ++   P    +  +P   +   PS  S  S SS      GST   L P  ++A  
Sbjct: 72  SRHSTTSHSSPGSTDTTLLPASTTTSGPSQESTTSHSSP-----GSTDTALSPGSTTALS 126

Query: 417 SGSPSDGGFISSDEYGSSPCDFRSSFRSVTPDSLGHTPPARGEEELSNYICMGGKGPSTL 476
            G         S  + SSP    S+  ++ PDS      + G  E S  +      P T 
Sbjct: 127 FGQ-------ESTTFHSSP---GSTHTTLFPDS----TTSSGIVEASTRVHSSTGSPRTT 172

Query: 477 TAPNGHYILSRGGNGHRCTPGTGLGTSPALAGDEAASAADLDNRFRKRT---HSAGTSPT 533
            +P      S G  G      T   T PA      +  +       + T    S G++PT
Sbjct: 173 LSPASS--TSPGLQGE----STAFQTHPASTHTTPSPPSTATAPVEESTTYHRSPGSTPT 226

Query: 534 ITHQKTPSQSSVASIEEYTEMMPAYPPGGGSGGRLPGHRHSAFVPTRSYPEEGLEMHPLE 593
            TH   P+ S+ +   E + +  + P   G+    P   HS    T    EE    H   
Sbjct: 227 -TH--FPASSTTSGHSEKSTIFHSSPDASGT---TPSSAHST---TSGVSEESSTSH--S 275

Query: 594 RRGGHHR---PDSSTLHTDDGYMPMSPGVAPVPSG-RKGSGDYMPMSPKSVSAPQQIINP 649
           + G  H    PDS+T       +   P  +    G  + + D  P  P + +AP ++   
Sbjct: 276 QPGSTHTTAFPDSTT----TSGLSQEPTTSHSSQGSTEATLDTTPSPPGTTAAPVEVSTT 331

Query: 650 IRRHPQRVDPNGYMMMSPSGGCSPDIGGGPSS-SSSSSNAVPSGTS 694
               P       +   S + G S +     SS  S+ + A+P  T+
Sbjct: 332 YHSRPSSTPTTHFSASSTTLGRSEESTTVHSSPGSTETTALPGSTT 377



 Score = 40.4 bits (93), Expect = 0.011
 Identities = 77/311 (24%), Positives = 117/311 (37%), Gaps = 47/311 (15%)

Query: 294 PSQVGLTRRSRTESI-TATSPASMVG-----------GKPGSFRVRASSDGEGTM----- 336
           PSQ   T  S   S  TA SP S                PGS       D   +      
Sbjct: 99  PSQESTTSHSSPGSTDTALSPGSTTALSFGQESTTFHSSPGSTHTTLFPDSTTSSGIVEA 158

Query: 337 -SRPASVDGSP---VSPSTNRTHAHRHRGSA-RLHPPLNHSRSIPMPASRCSPSATSPVS 391
            +R  S  GSP   +SP+++ +   +   +A + HP   H+   P P S    +AT+PV 
Sbjct: 159 STRVHSSTGSPRTTLSPASSTSPGLQGESTAFQTHPASTHTT--PSPPS----TATAPVE 212

Query: 392 LSSSSTSGHGSTSDCLFPRRSSASVSGSPSDGGFISSDEYGSSPCDFRSSFRSVTPD-SL 450
            S++     GST    FP  S+ S     S     S D  G++P    S+   V+ + S 
Sbjct: 213 ESTTYHRSPGSTPTTHFPASSTTSGHSEKSTIFHSSPDASGTTPSSAHSTTSGVSEESST 272

Query: 451 GHTPPARGEEELSNYICMGGKGPSTLTAPNGHYILSRGGNGHRCTPGTGLGTSPALAGDE 510
            H+ P  G    + +       P + T        +   +    T  T L T+P+  G  
Sbjct: 273 SHSQP--GSTHTTAF-------PDSTTTSGLSQEPTTSHSSQGSTEAT-LDTTPSPPGTT 322

Query: 511 AASAADLDNRFRKRTHSAGTSPTITHQKTPSQSSVASIEEYTEMMPAYPPGGGSGGRLPG 570
           AA            T+ +  S T T   + S +++   EE T +  +  PG      LPG
Sbjct: 323 AAPVE------VSTTYHSRPSSTPTTHFSASSTTLGRSEESTTVHSS--PGSTETTALPG 374

Query: 571 HRHSAFVPTRS 581
              +A +  +S
Sbjct: 375 STTTAGLSEKS 385


>gi|28559039 mediator complex subunit 1 [Homo sapiens]
          Length = 1581

 Score = 48.1 bits (113), Expect = 5e-05
 Identities = 59/260 (22%), Positives = 99/260 (38%), Gaps = 45/260 (17%)

Query: 314  ASMVGGKPGSFRVRASSDGEGTMSRPASVDGSPVS--------PSTNRTHAHRHRGSARL 365
            +S  GGKPGS  +       G+ S      G P S        P+ + +H+    GS +L
Sbjct: 1146 SSQSGGKPGSSPITKHGLSSGSSSTKMKPQGKPSSLMNPSLSKPNISPSHSRPPGGSDKL 1205

Query: 366  HPPLNHSRSIPMPASRCSPSATSPVSLSSSSTSGHGSTSDCLFPRRSSASVSGSPSDGGF 425
              P+      P+P +  S  A SP+S  S  +   G++S          S SG  S G  
Sbjct: 1206 ASPMK-----PVPGTPPSSKAKSPISSGSGGSHMSGTSSS-----SGMKSSSGLGSSGSL 1255

Query: 426  ISSDEYGSSPCDFRSSFRSVTPDSLGHTPPARGEEELSNYICMGGKGPSTLTAPN----- 480
                   S+ C   SS  S +  S+  +    G  +        GK PS    P+     
Sbjct: 1256 SQKTPPSSNSCTASSSSFSSSGSSMSSSQNQHGSSK--------GKSPSRNKKPSLTAVI 1307

Query: 481  ---GHYILSRGGNGHRCTPG-TGLGTSPA---------LAGDEAASAADLDNRFRKRTHS 527
                H +++ G  G     G  G+ T+ +         ++G E     +  ++ + +  +
Sbjct: 1308 DKLKHGVVTSGPGGEDPLDGQMGVSTNSSSHPMSSKHNMSGGEFQGKREKSDKDKSKVST 1367

Query: 528  AGTSPTITHQKTPSQSSVAS 547
            +G+S   + +KT    +V S
Sbjct: 1368 SGSS-VDSSKKTSESKNVGS 1386



 Score = 33.1 bits (74), Expect = 1.7
 Identities = 77/337 (22%), Positives = 112/337 (33%), Gaps = 40/337 (11%)

Query: 422  DGGFISSDEYGSSPCDFRSSFRSVTPDSLGHT---PPARGEEELSNYICMGGKGPS---- 474
            +G   S+        D +   RS TP + G +   PP R + +        GK PS    
Sbjct: 974  EGNGTSNSTLSGPGLDSKPGKRSRTPSNDGKSKDKPPKRKKADTE------GKSPSHSSS 1027

Query: 475  --TLTAPNGHYILSRGGNGHRCTPGTGLGTSP----ALAGDEAASAADLDNRFRKRTHSA 528
                T P         G+  R     G+ T P     +   +        +   + T S 
Sbjct: 1028 NRPFTPPTSTGGSKSPGSAGRSQTPPGVATPPIPKITIQIPKGTVMVGKPSSHSQYTSSG 1087

Query: 529  GTSPTITHQKTPSQSSVASIEEYTEMMPAYPPGGGSGGRLPGHRHSAFVPTRSYPEEGLE 588
              S + +       SS +S    +  M +    G S  +L    +S+   + S   +   
Sbjct: 1088 SVSSSGSKSHHSHSSSSSSSASTSGKMKSSKSEGSSSSKLSSSMYSSQGSSGSSQSKNSS 1147

Query: 589  MHPLERRGGHHRPDSSTLHTDDGYMPMSPGVAPVPSGRKGSGDYMPMSPKSVSAPQQIIN 648
                 + GG  +P SS + T  G    S      P G+  S     M+P S+S P   I+
Sbjct: 1148 -----QSGG--KPGSSPI-TKHGLSSGSSSTKMKPQGKPSS----LMNP-SLSKPN--IS 1192

Query: 649  PIRRHPQRVDPNGYMMMSPSGGCSPDIGGGPSSSSSSSNAVPSGTSYGKLWTNGVGGHHS 708
            P    P          M P  G  P        SS S  +  SGTS      +  G   S
Sbjct: 1193 PSHSRPPGGSDKLASPMKPVPGTPPSSKAKSPISSGSGGSHMSGTSSSSGMKSSSGLGSS 1252

Query: 709  HVLPHPKPPVESSGGKLLPCTGDYMNMSPVGDSNTSS 745
              L    PP  +S      CT    + S  G S +SS
Sbjct: 1253 GSLSQKTPPSSNS------CTASSSSFSSSGSSMSSS 1283



 Score = 32.7 bits (73), Expect = 2.2
 Identities = 77/327 (23%), Positives = 114/327 (34%), Gaps = 44/327 (13%)

Query: 265  RPRSKSQSSSNCSNPISVPLRRHHLNNPPPSQVGLTRRSRTESITATSPASMVGGK--PG 322
            +P  +S++ SN       P +R   +    S       S + S    +P +  GG   PG
Sbjct: 991  KPGKRSRTPSNDGKSKDKPPKRKKADTEGKSP------SHSSSNRPFTPPTSTGGSKSPG 1044

Query: 323  SFRVRASSDGEGTMSRPASVDGSPVSPSTNRTHAHRHRGSARLHPPLNHSRSIPMPASRC 382
            S          G    P  V   P+   T +      +G+  +  P +HS+     +   
Sbjct: 1045 S---------AGRSQTPPGVATPPIPKITIQIP----KGTVMVGKPSSHSQYTS--SGSV 1089

Query: 383  SPSATSPVSLSSSSTSGHGSTSDCLFPRRSSASVSGSPSDGGFISSDEYGSSPCDFRSSF 442
            S S +      SSS+S   STS  +   +S  S S   S   + S    GSS     SS 
Sbjct: 1090 SSSGSKSHHSHSSSSSSSASTSGKMKSSKSEGSSSSKLSSSMYSSQGSSGSSQSK-NSSQ 1148

Query: 443  RSVTPDSLGHTPPARGEEELSNYICMGGKGPS----TLTAPNGHYILSR--GGNGHRC-- 494
                P S   T         S  +   GK  S    +L+ PN     SR  GG+      
Sbjct: 1149 SGGKPGSSPITKHGLSSGSSSTKMKPQGKPSSLMNPSLSKPNISPSHSRPPGGSDKLASP 1208

Query: 495  ------TPGTGLGTSPALAGDEAASAADLDNRFRKRTHSAGTSPTITHQKTP--SQSSVA 546
                  TP +    SP  +G   +  +   +    ++ S   S     QKTP  S S  A
Sbjct: 1209 MKPVPGTPPSSKAKSPISSGSGGSHMSGTSSSSGMKSSSGLGSSGSLSQKTPPSSNSCTA 1268

Query: 547  SIEEY----TEMMPAYPPGGGSGGRLP 569
            S   +    + M  +    G S G+ P
Sbjct: 1269 SSSSFSSSGSSMSSSQNQHGSSKGKSP 1295


>gi|148806908 fibronectin type III domain containing 1 [Homo sapiens]
          Length = 1894

 Score = 48.1 bits (113), Expect = 5e-05
 Identities = 166/761 (21%), Positives = 243/761 (31%), Gaps = 148/761 (19%)

Query: 496  PGTGLGTSPALAGDEAASAADLDNRFRKRTHSAGTSPTITHQKTPSQSS----VASIEEY 551
            PG  L T P      +ASA+          H A T  T      P+  +    V S E+ 
Sbjct: 600  PGFSLATQPRPGAPPSASASP--------AHHASTQGTSHRPSLPASLNDNDLVDSDEDE 651

Query: 552  TEMMPAYPPGGGSGGRLPGHRHSAFVPTRSYPEEGLEMHPLERRGGHHRPDSSTLHTDDG 611
              +   +P G  +  R       A  P+R  P   L              D S++H    
Sbjct: 652  RAVGSLHPKGAFAQPR------PALSPSRQSPSSVLR-------------DRSSVH---- 688

Query: 612  YMPMSPGVAPVPSGRKGSGDYMPMSPKSVSAPQQIINPIRRHPQRVDPNGYMMMSP---- 667
                 PG  P    R+           S SAP   ++P      R+ P    + SP    
Sbjct: 689  -----PGAKPASPARRTPHSGAAEEDSSASAPPSRLSPPHGGSSRLLPTQPHLSSPLSKG 743

Query: 668  --SGGCSPDIGGGPSSSSSSSNAVPSGTSYGKLWTNGVGGHHSHVLPHPKPPVESSGGKL 725
               G  +P       S S+ S++V S  S     + G          H     E  GG+ 
Sbjct: 744  GKDGEDAPATNSNAPSRSTMSSSVSSHLSSRTQVSEGAEASDGE--SHGDGDRE-DGGRQ 800

Query: 726  LPCTGDYMNMSPVGD-----------SNTSSPSDCYYGPEDPQHKPVLSYYSLPRSFKHT 774
               T   +   P              +N  SPS    G   P+ +P  S  S   S  H 
Sbjct: 801  AEATAQTLRARPASGHFHLLRHKPFAANGRSPSRFSIG-RGPRLQPSSSPQSTVPSRAHP 859

Query: 775  QRPGEPEEGARHQHLRLST------SSGRLLYAATADDSSSSTSSDSLGGGYCGARLEPS 828
            + P   +      H +LS+         + L A   +D   S+S   +  G+   R  P 
Sbjct: 860  RVPSHSD-----SHPKLSSGIHGDEEDEKPLPATVVNDHVPSSSRQPISRGWEDLRRSPQ 914

Query: 829  LPHPHHQVLQPHLPRKVDTAAQTNSRLARPTRLSLGDPKASTLPRAREQQQQQQPLLHPP 888
                 H+  +P       T A T+ +             +S   +A++ QQ         
Sbjct: 915  RGASLHR-KEPIPENPKSTGADTHPQ----------GKYSSLASKAQDVQQSTDADTEGH 963

Query: 889  EPKS-PGEYVNIEFGSDQSGYLSGPVAFHSSPSVRCPSQLQP--APREEETGTEEYMKMD 945
             PK+ PG        +D+    + P A  S      P ++ P  AP+++        +  
Sbjct: 964  SPKAQPG-------STDRHASPARPPAARSQQHPSVPRRMTPGRAPQQQPPPPVATSQHH 1016

Query: 946  LGP-----GRRAAWQESTGVEMGRLGPAPPGAASICRPTRAVPSSRGDYMTMQMSCPRQS 1000
             GP     GR  +    +  + GR  P   G +          SS   Y          +
Sbjct: 1017 PGPQSRDAGRSPSQPRLSLTQAGRPRPTSQGRSH---------SSSDPYTASSRGMLPTA 1067

Query: 1001 YVDTSPAAPVSYADMRTGIAAEEVSLP----RATMAAASSSSAASA-SPTGPQGAAE--- 1052
              +    A  SY D  T + A++V  P    RA  AAAS        SPTG     +   
Sbjct: 1068 LQNQDEDAQGSYDDDSTEVEAQDVRAPAHAARAKEAAASLPKHQQVESPTGAGAGGDHRS 1127

Query: 1053 LAAHSSLLGGPQGPGGMSAFTRVNLSPNRNQSAKVIRADPQGCRRRHSSETFSSTPSATR 1112
               H++    P  PGG  +  RV   P+R    K   ++P   +R  SS++  S  +   
Sbjct: 1128 QRGHAASPARPSRPGGPQSRARV---PSRAAPGK---SEPPS-KRPLSSKSQQSVSAEDD 1180

Query: 1113 VGNTVPFGAGAAVGGGGGSSSSSEDVKRHSSASFENVWLRPGELGGAPKEPAKLCGAAGG 1172
                  F       GG     SS   K  SS++        G L    +EPA      GG
Sbjct: 1181 EEEDAGF-----FKGGKEDLLSSSVPKWPSSSTPRGGKDADGSLAKEEREPAIALAPRGG 1235

Query: 1173 LENGLNYIDLDLVKDFKQCPQECTPEPQPPPPPPPHQPLGS 1213
                                    P  +P PPPP   P  S
Sbjct: 1236 ---------------------SLAPVKRPLPPPPGSSPRAS 1255


>gi|46370073 GRB2-associated binding protein 1 isoform b [Homo
           sapiens]
          Length = 694

 Score = 47.4 bits (111), Expect = 9e-05
 Identities = 33/110 (30%), Positives = 53/110 (48%), Gaps = 18/110 (16%)

Query: 17  GYLRK--PKSMHKRF------FVLRAASEAGGPARLEYYENEKKWRHKSSAPKRSIPLES 68
           G+LRK  P+   KR+      FVLR+    G P  LEYY+N+      +  P R I L  
Sbjct: 10  GWLRKSPPEKKLKRYAWKRRWFVLRSGRLTGDPDVLEYYKND-----HAKKPIRIIDLNL 64

Query: 69  CFNIN-----KRADSKNKHLVALYTRDEHFAIAADSEAEQDSWYQALLQL 113
           C  ++      + + +N ++  + T D  F + ADSE E + W + +  +
Sbjct: 65  CQQVDAGLTFNKKEFENSYIFDINTIDRIFYLVADSEEEMNKWVRCICDI 114


>gi|46370071 GRB2-associated binding protein 1 isoform a [Homo
           sapiens]
          Length = 724

 Score = 47.4 bits (111), Expect = 9e-05
 Identities = 33/110 (30%), Positives = 53/110 (48%), Gaps = 18/110 (16%)

Query: 17  GYLRK--PKSMHKRF------FVLRAASEAGGPARLEYYENEKKWRHKSSAPKRSIPLES 68
           G+LRK  P+   KR+      FVLR+    G P  LEYY+N+      +  P R I L  
Sbjct: 10  GWLRKSPPEKKLKRYAWKRRWFVLRSGRLTGDPDVLEYYKND-----HAKKPIRIIDLNL 64

Query: 69  CFNIN-----KRADSKNKHLVALYTRDEHFAIAADSEAEQDSWYQALLQL 113
           C  ++      + + +N ++  + T D  F + ADSE E + W + +  +
Sbjct: 65  CQQVDAGLTFNKKEFENSYIFDINTIDRIFYLVADSEEEMNKWVRCICDI 114


>gi|4505939 DNA-directed RNA polymerase II A [Homo sapiens]
          Length = 1970

 Score = 47.4 bits (111), Expect = 9e-05
 Identities = 106/442 (23%), Positives = 147/442 (33%), Gaps = 63/442 (14%)

Query: 374  SIPMPASRCSPSATSPVSLSSSSTSGHGSTSDCLFPRRSSASVSGSPSDGGFISSDEYGS 433
            S P P    SP+ T     +  +T  +G+ S  +    +  +   SPS     S    G 
Sbjct: 1505 SAPSPMGGISPAMTP---WNQGATPAYGAWSPSVGSGMTPGAAGFSPSAASDASGFSPGY 1561

Query: 434  SPCDFRSSFRSVTPDSLGHTPPARGEEELSNYICMGGKGPSTLTAPNGHYILSRGGNGHR 493
            SP        S TP S G   P+      S YI   G   S   +P       R   G+ 
Sbjct: 1562 SPA------WSPTPGSPGSPGPS------SPYIPSPGGAMSPSYSPTSPAYEPRSPGGYT 1609

Query: 494  CTPGTGLGTSPALAGDEAASAADLDNRFRKRTHSAGTSPTITHQKTPSQSSVASIEEYTE 553
                +   TSP+ +    + +    N        + TSP+ +   +PS S  +    Y+ 
Sbjct: 1610 PQSPSYSPTSPSYSPTSPSYSPTSPNYSPTSPSYSPTSPSYS-PTSPSYSPTSP--SYSP 1666

Query: 554  MMPAYPPGGGS-GGRLPGHRHSA--FVPTR-SYPEEGLEMHPLERRGGHHRPDSSTLHTD 609
              P+Y P   S     P +  ++  + PT  SY        P         P  S   T 
Sbjct: 1667 TSPSYSPTSPSYSPTSPSYSPTSPSYSPTSPSYSPTSPSYSPTSPSYSPTSPSYSP--TS 1724

Query: 610  DGYMPMSPGVAPV-PSGRKGSGDYMPMSPK------SVSAPQQIINPIRRHPQRVDPNGY 662
              Y P SP  +P  PS    S +Y P SP       S S      +P   +     PN Y
Sbjct: 1725 PSYSPTSPSYSPTSPSYSPTSPNYSPTSPNYTPTSPSYSPTSPSYSPTSPNYTPTSPN-Y 1783

Query: 663  MMMSPS-GGCSPDIGG-GPSSSSSSSNAVPSGTSYGKLWTNGVGGHHSHVLPHPK----- 715
               SPS    SP      PS S SS    P   +Y     +      S+    PK     
Sbjct: 1784 SPTSPSYSPTSPSYSPTSPSYSPSSPRYTPQSPTYTPSSPSYSPSSPSYSPTSPKYTPTS 1843

Query: 716  --------------PPVESSGGKLLPCTGDYMNMSPVGD---------SNTSSPSDCYYG 752
                          P    +  K  P +  Y   SP            S T SP+   Y 
Sbjct: 1844 PSYSPSSPEYTPTSPKYSPTSPKYSPTSPKYSPTSPTYSPTTPKYSPTSPTYSPTSPVYT 1903

Query: 753  PEDPQHKPVLSYYSLPRSFKHT 774
            P  P++ P    YS P S K++
Sbjct: 1904 PTSPKYSPTSPTYS-PTSPKYS 1924



 Score = 45.4 bits (106), Expect = 3e-04
 Identities = 116/479 (24%), Positives = 171/479 (35%), Gaps = 69/479 (14%)

Query: 298  GLTRRSRTESITATSPASMVGGKPGSFRVRASSDGEGTMSRPASV----DGSPVSPSTNR 353
            G+T  +   S +A S AS  G  PG     + + G      P+S      G  +SPS + 
Sbjct: 1538 GMTPGAAGFSPSAASDAS--GFSPGYSPAWSPTPGSPGSPGPSSPYIPSPGGAMSPSYSP 1595

Query: 354  THAHRHRGSARLHPPLNHSRSIPMPASRCSPSATSPVSLSSSSTSGHGSTSDCLFPRRSS 413
            T       S   + P + S S   P+   +  + SP S + S TS   S +    P  S 
Sbjct: 1596 TSPAYEPRSPGGYTPQSPSYSPTSPSYSPTSPSYSPTSPNYSPTSPSYSPTS---PSYSP 1652

Query: 414  ASVSGSPSDGGFI-SSDEYGSSPCDFRSSFRSVTPDSLGHTPPARGEEELSNYICMGGKG 472
             S S SP+   +  +S  Y  +   +  +  S +P S  ++P +      S         
Sbjct: 1653 TSPSYSPTSPSYSPTSPSYSPTSPSYSPTSPSYSPTSPSYSPTSPSYSPTS--------- 1703

Query: 473  PS-TLTAPNGHYILSRGGNGHRCTPGTGLGTSPALAGDEAASAADLDNRFRKRTHSAGTS 531
            PS + T+P+     S     +  T  +   TSP+ +    + +    N      +   TS
Sbjct: 1704 PSYSPTSPS----YSPTSPSYSPTSPSYSPTSPSYSPTSPSYSPTSPNYSPTSPNYTPTS 1759

Query: 532  PTITHQKTPSQSSVASIEEYTEMMPAYPPGGGSGGRLPGHRHSAFVPTR-SYPEEGLEMH 590
            P+ +   +PS S  +    YT   P Y P   S           + PT  SY        
Sbjct: 1760 PSYS-PTSPSYSPTSP--NYTPTSPNYSPTSPS-----------YSPTSPSYSPTSPSYS 1805

Query: 591  PLERRGGHHRPDSSTLHTDDGYMPMSPGVAPV-PSGRKGSGDYMPMSPK-SVSAPQQIIN 648
            P   R   + P S T      Y P SP  +P  PS    S  Y P SP  S S+P+    
Sbjct: 1806 PSSPR---YTPQSPT------YTPSSPSYSPSSPSYSPTSPKYTPTSPSYSPSSPEYTPT 1856

Query: 649  PIRRHPQRVDPNGYMMMSPSGGCSPDIGGGPSSSSSSSNAVPSGTSYGKLWTNGVGGHHS 708
              +  P    P  Y   SP    SP     P+ S ++    P+  +Y            S
Sbjct: 1857 SPKYSP--TSPK-YSPTSPK--YSPT---SPTYSPTTPKYSPTSPTYSPT---------S 1899

Query: 709  HVLPHPKPPVESSGGKLLPCTGDYMNMSPVGDSNTSSPSDCYYGPEDPQHKPVLSYYSL 767
             V     P    +     P +  Y   SP    + +SP    Y P  P + P    YSL
Sbjct: 1900 PVYTPTSPKYSPTSPTYSPTSPKYSPTSPT--YSPTSPKGSTYSPTSPGYSPTSPTYSL 1956



 Score = 38.5 bits (88), Expect = 0.040
 Identities = 43/155 (27%), Positives = 58/155 (37%), Gaps = 13/155 (8%)

Query: 622  VPSGRKGSGDYMPMSPKSVSAPQQI--INPIRRHPQRVDPNGYMMMSPSGGCSPDIGGGP 679
            +P+   G G   P      SAP  +  I+P      +     Y   SPS G     G   
Sbjct: 1486 IPTNIPGLGAAGPTGMFFGSAPSPMGGISPAMTPWNQGATPAYGAWSPSVGSGMTPGAAG 1545

Query: 680  SSSSSSSNAVPSGTSYGKLWTNGVGGHHSHVLPHPKPP-VESSGGKL----LPCTGDYMN 734
             S S++S+A      Y   W+   G   S   P P  P + S GG +     P +  Y  
Sbjct: 1546 FSPSAASDASGFSPGYSPAWSPTPGSPGS---PGPSSPYIPSPGGAMSPSYSPTSPAYEP 1602

Query: 735  MSPVG---DSNTSSPSDCYYGPEDPQHKPVLSYYS 766
             SP G    S + SP+   Y P  P + P    YS
Sbjct: 1603 RSPGGYTPQSPSYSPTSPSYSPTSPSYSPTSPNYS 1637


>gi|239752594 PREDICTED: hypothetical protein, partial [Homo
           sapiens]
          Length = 673

 Score = 46.6 bits (109), Expect = 1e-04
 Identities = 113/487 (23%), Positives = 171/487 (35%), Gaps = 60/487 (12%)

Query: 294 PSQVGLTRRSRTESITATSPASMVGGKPGSFRVRASSDGEGTMSRPASVDGSPVSPSTNR 353
           PS+   TR   T S+T T   + + G P +  +       GT SR AS+ G+P   S   
Sbjct: 8   PSRASPTRTPSTASLTGTPSRASLTGTPSTASLM------GTPSR-ASLTGTPPRASLKG 60

Query: 354 THAHRHRGSARLHPPLNHSRSIPMPASRCSPSATSPVSLSSSSTSGHGSTSDCLFPRRSS 413
           T +      +     L   +S  +     +PS  S   +   ++         L  R S+
Sbjct: 61  TTSMASLMVSPSRASLTRMQSSSLLTR--TPSMASLKRMPPRASRTRTLPRASLMRRPST 118

Query: 414 ASVSGSPSDGGFISSDEYGSSPCDFRSSFRSVTPD--SLGHTPPARGEEELSNYICMGGK 471
           AS++ SPS     ++    S      ++     P   SL  TPP R    ++        
Sbjct: 119 ASLTRSPSRASLTTTPSRASLSMTPSTAAALTMPSRASLTRTPP-RASLTMT-------- 169

Query: 472 GPSTLTAPNGHYILSRGGNGHRCTPGTGLGTSPALAGDEAASAADLDNRFRKRTHSAGTS 531
            PST +        S  G   R +P TG+ ++ +L   ++ ++     R   R    GT 
Sbjct: 170 -PSTASLTRTPPRASPTGMPSRTSP-TGMPSTASLTKMDSTASI---TRTLSRASPTGTP 224

Query: 532 PTITHQKTPSQSSVASIEEYTEMMPAYPPGGGSGGRLPGHRHSAFVPTRSYPEEGLEMHP 591
           P  +   +P ++S+ S+   T ++   PP     G L     +    T S          
Sbjct: 225 PRASPTGSPPRASL-SMMPSTALLIRTPPRASPTGMLSRTSLTKMDSTASITRTPSRPST 283

Query: 592 LERRGGHHRPDSSTLHTDDGYMPMSPGVAPVPSGRKGSGDYMPMSPKSVSAPQQIINPIR 651
               G   R   S   +    M M P  +P     + S   M  +      P +    I 
Sbjct: 284 ASPTGTPSRASLSMTPSTASLMRMLPRASPTGMLSRTSLTKMDSTASISRTPPRA--SIT 341

Query: 652 RHPQRVDPNGY-MMMSPSGGCS-PDIGGGPSSSS---SSSNAVPSGT------------- 693
           R P R  P G     SP+G  S     G PS++S    SS A P+GT             
Sbjct: 342 RTPSRASPTGKPSTASPTGTPSRASPTGSPSTASLTGLSSTASPTGTPPRASPTGTPSTA 401

Query: 694 ----------SYGKLWTNGVGGHHSHVLPHPKPPVESSGG---KLLPCTGDYMNMSPVGD 740
                       G L    +    S   P   PP  S  G   +  P TG     SP G 
Sbjct: 402 SLTRKPPRASPTGMLSRTSITKMDSTASPTRTPPRASPTGTPPRASP-TGTPSRASPTGT 460

Query: 741 SNTSSPS 747
            +T+SP+
Sbjct: 461 QSTASPT 467



 Score = 34.7 bits (78), Expect = 0.58
 Identities = 47/175 (26%), Positives = 65/175 (37%), Gaps = 24/175 (13%)

Query: 267 RSKSQSSSNCSNPISVPLRRHHLNNPPPSQVGLTRRSRTESITATSPASMVGGKPGSFRV 326
           R+      + ++P   P R     +P  S   LT  S T S T T P +   G P +  +
Sbjct: 346 RASPTGKPSTASPTGTPSRASPTGSP--STASLTGLSSTASPTGTPPRASPTGTPSTASL 403

Query: 327 -----RASSDGEGTMSRPASVDGSPVSPSTNRTHAHRHRGSARLHPPLNHSRSIPMPASR 381
                RAS  G  + +    +D S  SP+     A       R  P    SR+ P     
Sbjct: 404 TRKPPRASPTGMLSRTSITKMD-STASPTRTPPRASPTGTPPRASPTGTPSRASPTGTQS 462

Query: 382 C-----SPSATSPVSLSSSSTSGHGSTSDCLFPR----------RSSASVSGSPS 421
                 SPS  SP   S S+ S  GS S     R           S+AS++ +PS
Sbjct: 463 TASPTGSPSTASPTG-SPSTASPTGSPSRASLTRTPSRASLTKMESTASITRTPS 516


>gi|7662236 TSC22 domain family, member 2 [Homo sapiens]
          Length = 780

 Score = 46.6 bits (109), Expect = 1e-04
 Identities = 66/282 (23%), Positives = 103/282 (36%), Gaps = 51/282 (18%)

Query: 830  PHPHHQVLQPHLPRKVDTAAQTNSRLARPTRLSLGDPKASTLPR-----AREQQQQQQPL 884
            P P     QP  P+      QT      PT ++L  P  S  P+          QQ Q  
Sbjct: 302  PQPMMAAAQPSQPQGAGPGGQT----LPPTNVTLAQPAMSLPPQPGPAVGAPAAQQPQQF 357

Query: 885  LHPPEPKSPGEYVNIEFGSDQSGYLSGPVAFHSSPSVRCPSQLQPAPREEETGTEEYMKM 944
             +P     PG  + ++  S QS YL   VA    PS   PS    A       T     +
Sbjct: 358  AYPQPQIPPGHLLPVQ-PSGQSEYLQQHVAGLQPPSPAQPSSTGAAASPATAAT-----L 411

Query: 945  DLGPGRRAAWQESTGVEM------------GRLGPAPPGAASICRPTRAVPSSRGDYMT- 991
             +G G+ A+   S G ++             R GPA  G  + C+PT   P++ G  +  
Sbjct: 412  PVGTGQNAS---SVGAQLMGASSQPSEAMAPRTGPAQGGQVAPCQPTGVPPATVGGVVQP 468

Query: 992  --------MQMSCPRQSYVDTSP--AAPVSYADMRTGIAAEEVSLPRATMAAASSSSAAS 1041
                       S P      + P  A P     +  G+     ++P  ++ + S++S   
Sbjct: 469  CLGPAGAGQPQSVPPPQMGGSGPLSAVPGGPHAVVPGVPNVPAAVPAPSVPSVSTTSVTM 528

Query: 1042 ASPTGPQG-AAELAAHSSL---------LGGPQGPGGMSAFT 1073
             +   P   + +L++H+ +         +G P  PG  SA T
Sbjct: 529  PNVPAPLAQSQQLSSHTPVSRSSSIIQHVGLPLAPGTHSAPT 570



 Score = 35.0 bits (79), Expect = 0.45
 Identities = 48/209 (22%), Positives = 72/209 (34%), Gaps = 32/209 (15%)

Query: 856  ARPTRLSLGDPKASTLPRAREQQQQQQPL------LHPPEPKSPGEYVNIEFGSDQSGYL 909
            A+P   S+G P+    P      Q   PL         P+P       +   G+   G  
Sbjct: 264  AQPQSFSVGQPQPPPPPVGGAVAQSSAPLPPFPGAATGPQPMMAAAQPSQPQGAGPGGQT 323

Query: 910  SGPVAFH-SSPSVRCPSQLQPA---PREEETGTEEYMKMDLGPGRRAAWQESTGVEMGRL 965
              P     + P++  P Q  PA   P  ++     Y +  + PG     Q S     G+ 
Sbjct: 324  LPPTNVTLAQPAMSLPPQPGPAVGAPAAQQPQQFAYPQPQIPPGHLLPVQPS-----GQS 378

Query: 966  GPAPPGAASICRPTRAVPSSRGDYMTMQMSCPRQSYVDTSPAAPVSYADMRTGIAAEEVS 1025
                   A +  P+ A PSS G                 + A+P + A +  G      S
Sbjct: 379  EYLQQHVAGLQPPSPAQPSSTG-----------------AAASPATAATLPVGTGQNASS 421

Query: 1026 LPRATMAAASSSSAASASPTGPQGAAELA 1054
            +    M A+S  S A A  TGP    ++A
Sbjct: 422  VGAQLMGASSQPSEAMAPRTGPAQGGQVA 450


>gi|83716021 GRB2-associated binding protein family, member 4 [Homo
           sapiens]
          Length = 574

 Score = 45.4 bits (106), Expect = 3e-04
 Identities = 35/137 (25%), Positives = 58/137 (42%), Gaps = 22/137 (16%)

Query: 17  GYLRKPK--------SMHKRFFVLRAASEAGGPARLEYYENEKKWRHKSSAPKRSIPLES 68
           G+LRK          +  KR+F+LR    +  P  LEYY+N+      S  P R+I L  
Sbjct: 44  GWLRKSPPEKKLRLFAWRKRWFILRRGQTSSDPDVLEYYKND-----GSKKPLRTINLNL 98

Query: 69  C--------FNINKRADSKNKHLVALYTRDEHFAIAADSEAEQDSWYQALLQLHNRAKGH 120
           C         N NK+   K  ++  + T +  F + A++  + + W Q++ Q+    +  
Sbjct: 99  CEQLDVDVTLNFNKKEIQKG-YMFDIKTSERTFYLVAETREDMNEWVQSICQICGFRQEE 157

Query: 121 HDGAAALGAGGGGGSCS 137
             G     +    G CS
Sbjct: 158 STGFLGNISSASHGLCS 174


>gi|126091130 Gab3 protein isoform 1 [Homo sapiens]
          Length = 587

 Score = 45.4 bits (106), Expect = 3e-04
 Identities = 36/106 (33%), Positives = 48/106 (45%), Gaps = 14/106 (13%)

Query: 27  KRFFVLRAASEAGGPARLEYYENEKKWRHKSSAPKRSIPLESCFNINK------RADSKN 80
           KR+FVLR    +G P  LEYY N+      SS P R I L  C           R + +N
Sbjct: 28  KRWFVLRRGRMSGNPDVLEYYRNK-----HSSKPIRVIDLSECAVWKHVGPSFVRKEFQN 82

Query: 81  KHLVALYTRDEHFAIAADSEAEQDSWYQALLQLHNRAKGH-HDGAA 125
             +  + T    F + A +E E   W  ++ Q+ N   GH  DGAA
Sbjct: 83  NFVFIVKTTSRTFYLVAKTEQEMQVWVHSISQVCN--LGHLEDGAA 126


>gi|182765442 homeobox A10 isoform a [Homo sapiens]
          Length = 410

 Score = 44.7 bits (104), Expect = 6e-04
 Identities = 39/126 (30%), Positives = 52/126 (41%), Gaps = 17/126 (13%)

Query: 1120 GAGAAVGGGGGSSSSSEDVKRHSSASF----ENVWLRPGELGGAPKEPAK--LCGAAGGL 1173
            G G A GGGGG   +   V    +A      ++  L P  LGG   E A     G  GGL
Sbjct: 45   GGGGAGGGGGGGYYAHGGVYLPPAADLPYGLQSCGLFP-TLGGKRNEAASPGSGGGGGGL 103

Query: 1174 ENGLNYIDLDLVKDFKQCPQECTPEP----------QPPPPPPPHQPLGSGESSSTRRSS 1223
              G +      +  +   P+ C  EP          QPPPPP P QP     S S  ++ 
Sbjct: 104  GPGAHGYGPSPIDLWLDAPRSCRMEPPDGPPPPPQQQPPPPPQPPQPAPQATSCSFAQNI 163

Query: 1224 EDLSAY 1229
            ++ S+Y
Sbjct: 164  KEESSY 169


>gi|18079323 Gab3 protein isoform 2 [Homo sapiens]
          Length = 586

 Score = 44.3 bits (103), Expect = 7e-04
 Identities = 35/108 (32%), Positives = 49/108 (45%), Gaps = 14/108 (12%)

Query: 27  KRFFVLRAASEAGGPARLEYYENEKKWRHKSSAPKRSIPLESCFNINK------RADSKN 80
           KR+FVLR    +G P  LEYY N+      SS P R I L  C           R + +N
Sbjct: 28  KRWFVLRRGRMSGNPDVLEYYRNK-----HSSKPIRVIDLSECAVWKHVGPSFVRKEFQN 82

Query: 81  KHLVALYTRDEHFAIAADSEAEQDSWYQALLQLHNRAKGH-HDGAAAL 127
             +  + T    F + A +E E   W  ++ Q+ N   GH  DGA ++
Sbjct: 83  NFVFIVKTTSRTFYLVAKTEQEMQVWVHSISQVCN--LGHLEDGADSM 128


>gi|221139926 NHS-like 1 [Homo sapiens]
          Length = 1606

 Score = 43.5 bits (101), Expect = 0.001
 Identities = 68/298 (22%), Positives = 103/298 (34%), Gaps = 42/298 (14%)

Query: 286  RHHLNNPPPSQVGLTRRSRTESITATSPASMVGGKPGSFRVRASSDGEGTMSRPASVDGS 345
            ++HL    PS    +R S  E  + + PAS+    P   +  +  D      R   V  S
Sbjct: 1107 QYHLK---PSAFLKSRNSTNEMESESQPASVTSSLPTPAKSSSQGDHGSAAERGGPVSRS 1163

Query: 346  PVSPSTNRTHAHRHRGS--------ARLHPPLNHSRS----IPMP----ASRCSPSATSP 389
            P +PS     A     +        +R  PP++        +P P    A   + + +  
Sbjct: 1164 PGAPSAGEAEARPSPSTTPLPDSSPSRKPPPISKKPKLFLVVPPPQKDFAVEPAENVSEA 1223

Query: 390  VSLSSSSTSGHGSTSDCLFPRRSSASVSGSPSDGGFISSDEYGS----SPCDFRSSFRSV 445
            +    S T+G   +      + SSA+ +GS +     S  E G+    SP    ++   V
Sbjct: 1224 LRAVPSPTTGEEGSVHSREAKESSAAQAGSHATHPGTSVLEGGAAGSMSPSRVEANVPMV 1283

Query: 446  TPDSLGHTPPARGEEELSNYICMGGKGPSTLTAPNGHY----------------ILSRGG 489
             PD    +P  + EE   N    GG G S L+  +G                   L   G
Sbjct: 1284 QPDV---SPAPKQEEPAENSADTGGDGESCLSQQDGAAGVPETNAAGSSSEACDFLKEDG 1340

Query: 490  NGHRCTPGTGLGTSPALAGDEAASAADLDNRFRKRTHSAGTSPTITHQKTPSQSSVAS 547
            N    TP     T    A    +    L  R     HS   SP+     T +  S+AS
Sbjct: 1341 NDEVMTPSRPRTTEDLFAAIHRSKRKVLGRRDSDDDHSRNHSPSPPVTPTGAAPSLAS 1398


  Database: hs.faa
    Posted date:  Aug 4, 2009  4:42 PM
  Number of letters in database: 18,247,518
  Number of sequences in database:  37,866
  
Lambda     K      H
   0.311    0.129    0.386 

Gapped
Lambda     K      H
   0.267   0.0410    0.140 


Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Hits to DB: 62,528,478
Number of Sequences: 37866
Number of extensions: 3774978
Number of successful extensions: 30303
Number of sequences better than 10.0: 30
Number of HSP's better than 10.0 without gapping: 161
Number of HSP's successfully gapped in prelim test: 602
Number of HSP's that attempted gapping in prelim test: 23711
Number of HSP's gapped (non-prelim): 6174
length of query: 1242
length of database: 18,247,518
effective HSP length: 114
effective length of query: 1128
effective length of database: 13,930,794
effective search space: 15713935632
effective search space used: 15713935632
T: 11
A: 40
X1: 16 ( 7.2 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 42 (21.8 bits)
S2: 68 (30.8 bits)

Search results were obtained with NCBI BLAST and RefSeq entries.

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Guide to the Human Genome
Copyright © 2010 by Stewart Scherer. All rights reserved.