Guide to the Human Genome
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Name: GAB1 Sequence: fasta or formatted (724aa) NCBI GI: 46370071
Description:

GRB2-associated binding protein 1 isoform a

Referenced in:

Inositol Pathways
Receptor Tyrosine Kinases

Other entries for this name:
alt prot [694aa] GRB2-associated binding protein 1 isoform b
Composition:

amino acid map
 Amino acid        Percentage    Count  Longest homopolymer
 A alanine             4.4         32           1
 C cysteine            1.5         11           1
 D aspartate           7.3         53           1
 E glutamate           5.4         39           3
 F phenylalanine       3.0         22           2
 G glycine             4.6         33           2
 H histidine           2.2         16           1
 I isoleucine          4.0         29           2
 K lysine              5.8         42           2
 L leucine             6.2         45           3
 M methionine          1.8         13           1
 N asparagine          4.3         31           1
 P proline            11.9         86           3
 Q glutamine           3.7         27           3
 R arginine            5.5         40           2
 S serine             13.1         95           3
 T threonine           6.2         45           2
 V valine              5.4         39           3
 W tryptophan          0.8          6           1
 Y tyrosine            2.8         20           2
Comparative genomics:

Search single species RefSeq proteins at NCBI
   H. sapiens
   M. musculus
   D. rerio
   C. intestinalis
   S. purpuratus
   D. melanogaster
   C. elegans
   A. thaliana
   S. cerevisiae
   E. coli W3110
   A. pernix K1

Search summary

comparative genomics plot

   Figure data

Additional searches of
RefSeq proteins at NCBI

   All
   Eukaryotes
   Bacteria
   Archaea
   Viruses
   Primates
   Mammals
   Vertebrates

Related human proteins:
Protein          Relative score         Description

Self-match            1.000   GRB2-associated binding protein 1 isoform a 
GAB1                  0.948   GRB2-associated binding protein 1 isoform b 
GAB2                  0.266   GRB2-associated binding protein 2 isoform a 
GAB2                  0.217   GRB2-associated binding protein 2 isoform b 
GAB3                  0.139   Gab3 protein isoform 1 
GAB3                  0.138   Gab3 protein isoform 2 
GAB4                  0.098   GRB2-associated binding protein family, member 4 [Ho...
PLEKHA1               0.021   pleckstrin homology domain containing, family A (pho...
PLEKHA1               0.021   pleckstrin homology domain containing, family A (pho...
PLEKHH1               0.020   pleckstrin homology domain containing, family H (wit...
MYO10                 0.019   myosin X 
PHLDB2                0.016   pleckstrin homology-like domain, family B, member 2...
PHLDB2                0.016   pleckstrin homology-like domain, family B, member 2...
PHLDB2                0.016   pleckstrin homology-like domain, family B, member 2...
PHLDB2                0.016   pleckstrin homology-like domain, family B, member 2 ...
PLEK                  0.016   pleckstrin 
SRRM2                 0.016   splicing coactivator subunit SRm300 
IRS1                  0.015   insulin receptor substrate 1 
IRS2                  0.015   insulin receptor substrate 2 
PLEKHH2               0.015   pleckstrin homology domain containing, family H (wi...
PLEKHA2               0.015   pleckstrin homology domain containing, family A (ph...
BTBD12                0.015   BTB (POZ) domain containing 12 
MUC16                 0.014   mucin 16 
MUC2                  0.014   mucin 2 precursor 
FLJ22184              0.014   PREDICTED: hypothetical protein FLJ22184 
POLR2A                0.014   DNA-directed RNA polymerase II A 
PHLDB1                0.014   pleckstrin homology-like domain, family B, member 1...
PHLDB1                0.013   pleckstrin homology-like domain, family B, member 1...
PHLDB1                0.013   pleckstrin homology-like domain, family B, member 1 ...
CNKSR1                0.013   connector enhancer of kinase suppressor of Ras 1 [H...
Human BLASTP results (used to prepare the table)

Gene descriptions are from NCBI RefSeq. Search results were obtained with NCBI BLAST and RefSeq entries. When identical proteins are present, the self-match may not be listed first in BLASTP output. In such cases, the table above has been reordered to place it first.

See About the Figures for the scoring system used in the figure above right. The same scoring system was used in the table of BLASTP results.


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Guide to the Human Genome
Copyright © 2010 by Stewart Scherer. All rights reserved.

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