Guide to the Human Genome
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Name: GAB4 Sequence: fasta or formatted (574aa) NCBI GI: 83716021
Description:

GRB2-associated binding protein family, member 4

Referenced in:

Inositol Pathways
Receptor Tyrosine Kinases

Composition:

amino acid map
 Amino acid        Percentage    Count  Longest homopolymer
 A alanine             5.6         32           2
 C cysteine            2.3         13           1
 D aspartate           3.7         21           2
 E glutamate           5.6         32           2
 F phenylalanine       3.3         19           1
 G glycine             7.8         45           3
 H histidine           4.2         24           1
 I isoleucine          3.1         18           1
 K lysine              4.0         23           2
 L leucine             7.5         43           2
 M methionine          1.7         10           1
 N asparagine          4.0         23           2
 P proline             9.6         55           2
 Q glutamine           5.2         30           1
 R arginine            5.2         30           2
 S serine             14.3         82           4
 T threonine           5.2         30           1
 V valine              4.5         26           1
 W tryptophan          1.4          8           1
 Y tyrosine            1.7         10           2
Comparative genomics:

Search single species RefSeq proteins at NCBI
   H. sapiens
   M. musculus
   D. rerio
   C. intestinalis
   S. purpuratus
   D. melanogaster
   C. elegans
   A. thaliana
   S. cerevisiae
   E. coli W3110
   A. pernix K1

Search summary

comparative genomics plot

   Figure data

Additional searches of
RefSeq proteins at NCBI

   All
   Eukaryotes
   Bacteria
   Archaea
   Viruses
   Primates
   Mammals
   Vertebrates

Related human proteins:
Protein          Relative score         Description

Self-match            1.000   GRB2-associated binding protein family, member 4 [Ho... 
GAB2                  0.289   GRB2-associated binding protein 2 isoform a 
GAB2                  0.241   GRB2-associated binding protein 2 isoform b 
GAB1                  0.124   GRB2-associated binding protein 1 isoform b 
GAB1                  0.124   GRB2-associated binding protein 1 isoform a 
GAB3                  0.094   Gab3 protein isoform 1 
GAB3                  0.094   Gab3 protein isoform 2 
MYO10                 0.027   myosin X 
PLEKHA2               0.027   pleckstrin homology domain containing, family A (ph...
DOCK10                0.021   dedicator of cytokinesis 10 
ARAP1                 0.021   ArfGAP with RhoGAP domain, ankyrin repeat and PH do...
ARAP1                 0.021   ArfGAP with RhoGAP domain, ankyrin repeat and PH do...
ARAP1                 0.021   ArfGAP with RhoGAP domain, ankyrin repeat and PH dom...
PLEKHA1               0.021   pleckstrin homology domain containing, family A (pho...
PLEKHA1               0.021   pleckstrin homology domain containing, family A (pho...
PLEK                  0.021   pleckstrin 
DAPP1                 0.020   dual adaptor of phosphotyrosine and 3-phosphoinosit...
CNKSR2                0.018   connector enhancer of kinase suppressor of Ras 2 [Ho...
IRS1                  0.017   insulin receptor substrate 1 
ARHGAP24              0.017   Rho GTPase activating protein 24 isoform 1 
ARHGAP22              0.017   Rho GTPase activating protein 2 
C10orf81              0.016   hypothetical protein LOC79949 
PLEKHH1               0.016   pleckstrin homology domain containing, family H (wit...
IPCEF1                0.015   phosphoinositide-binding protein PIP3-E isoform 1 [...
IPCEF1                0.015   phosphoinositide-binding protein PIP3-E isoform 1 [...
IPCEF1                0.015   phosphoinositide-binding protein PIP3-E isoform 2 [H...
PHLDB2                0.015   pleckstrin homology-like domain, family B, member 2...
PHLDB2                0.015   pleckstrin homology-like domain, family B, member 2...
PHLDB2                0.015   pleckstrin homology-like domain, family B, member 2...
PHLDB2                0.015   pleckstrin homology-like domain, family B, member 2 ...
Human BLASTP results (used to prepare the table)

Gene descriptions are from NCBI RefSeq. Search results were obtained with NCBI BLAST and RefSeq entries. When identical proteins are present, the self-match may not be listed first in BLASTP output. In such cases, the table above has been reordered to place it first.

See About the Figures for the scoring system used in the figure above right. The same scoring system was used in the table of BLASTP results.


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Guide to the Human Genome
Copyright © 2010 by Stewart Scherer. All rights reserved.

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