BLASTP 2.2.11 [Jun-05-2005] Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer, Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), "Gapped BLAST and PSI-BLAST: a new generation of protein database search programs", Nucleic Acids Res. 25:3389-3402. Query= gi|48255889 protein kinase C substrate 80K-H isoform 1 [Homo sapiens] (528 letters) Database: hs.faa 37,866 sequences; 18,247,518 total letters Searching..................................................done Score E Sequences producing significant alignments: (bits) Value gi|48255889 protein kinase C substrate 80K-H isoform 1 [Homo sap... 1096 0.0 gi|48255891 protein kinase C substrate 80K-H isoform 2 [Homo sap... 1069 0.0 gi|84043963 eukaryotic translation initiation factor 5B [Homo sa... 65 1e-10 gi|221219020 NYD-SP11 protein [Homo sapiens] 65 2e-10 gi|16332372 cell division cycle 2-like 1 (PITSLRE proteins) isof... 64 4e-10 gi|16332362 cell division cycle 2-like 1 (PITSLRE proteins) isof... 64 4e-10 gi|148763345 cell division cycle 2-like 2 isoform 4 [Homo sapiens] 62 1e-09 gi|4505257 moesin [Homo sapiens] 62 1e-09 gi|16332364 cell division cycle 2-like 1 (PITSLRE proteins) isof... 62 2e-09 gi|16332358 cell division cycle 2-like 1 (PITSLRE proteins) isof... 62 2e-09 gi|239756241 PREDICTED: golgi autoantigen, golgin subfamily a-li... 61 2e-09 gi|155030232 proline, glutamic acid and leucine rich protein 1 [... 61 2e-09 gi|222418637 golgi autoantigen, golgin subfamily a-like [Homo sa... 61 3e-09 gi|148763347 cell division cycle 2-like 2 isoform 1 [Homo sapiens] 59 8e-09 gi|16332370 cell division cycle 2-like 1 (PITSLRE proteins) isof... 59 1e-08 gi|239745089 PREDICTED: golgi autoantigen, golgin subfamily a-li... 58 2e-08 gi|17975763 myelin transcription factor 1 [Homo sapiens] 57 3e-08 gi|100816397 MYST histone acetyltransferase (monocytic leukemia)... 57 3e-08 gi|117414137 retinitis pigmentosa 1-like 1 [Homo sapiens] 57 3e-08 gi|14249738 N-acetylglucosamine-1-phosphotransferase, gamma subu... 57 5e-08 gi|154759293 cysteine-rich hydrophobic domain 1 [Homo sapiens] 57 5e-08 gi|239745079 PREDICTED: Putative golgin subfamily A member 6-lik... 55 1e-07 gi|148746195 trichohyalin [Homo sapiens] 55 1e-07 gi|24307879 dynein, cytoplasmic 1, intermediate chain 2 [Homo sa... 55 1e-07 gi|222446603 golgi autoantigen, golgin subfamily a-like [Homo sa... 55 2e-07 gi|157738649 neurofilament, medium polypeptide 150kDa isoform 1 ... 55 2e-07 gi|157738641 neurofilament, medium polypeptide 150kDa isoform 2 ... 55 2e-07 gi|55741709 RNA binding motif protein 25 [Homo sapiens] 54 3e-07 gi|118600967 shroom family member 4 [Homo sapiens] 54 5e-07 gi|239745095 PREDICTED: hypothetical protein LOC645202 [Homo sap... 54 5e-07 >gi|48255889 protein kinase C substrate 80K-H isoform 1 [Homo sapiens] Length = 528 Score = 1096 bits (2834), Expect = 0.0 Identities = 528/528 (100%), Positives = 528/528 (100%) Query: 1 MLLPLLLLLPMCWAVEVKRPRGVSLTNHHFYDESKPFTCLDGSATIPFDQVNDDYCDCKD 60 MLLPLLLLLPMCWAVEVKRPRGVSLTNHHFYDESKPFTCLDGSATIPFDQVNDDYCDCKD Sbjct: 1 MLLPLLLLLPMCWAVEVKRPRGVSLTNHHFYDESKPFTCLDGSATIPFDQVNDDYCDCKD 60 Query: 61 GSDEPGTAACPNGSFHCTNTGYKPLYIPSNRVNDGVCDCCDGTDEYNSGVICENTCKEKG 120 GSDEPGTAACPNGSFHCTNTGYKPLYIPSNRVNDGVCDCCDGTDEYNSGVICENTCKEKG Sbjct: 61 GSDEPGTAACPNGSFHCTNTGYKPLYIPSNRVNDGVCDCCDGTDEYNSGVICENTCKEKG 120 Query: 121 RKERESLQQMAEVTREGFRLKKILIEDWKKAREEKQKKLIELQAGKKSLEDQVEMLRTVK 180 RKERESLQQMAEVTREGFRLKKILIEDWKKAREEKQKKLIELQAGKKSLEDQVEMLRTVK Sbjct: 121 RKERESLQQMAEVTREGFRLKKILIEDWKKAREEKQKKLIELQAGKKSLEDQVEMLRTVK 180 Query: 181 EEAEKPEREAKEQHQKLWEEQLAAAKAQQEQELAADAFKELDDDMDGTVSVTELQTHPEL 240 EEAEKPEREAKEQHQKLWEEQLAAAKAQQEQELAADAFKELDDDMDGTVSVTELQTHPEL Sbjct: 181 EEAEKPEREAKEQHQKLWEEQLAAAKAQQEQELAADAFKELDDDMDGTVSVTELQTHPEL 240 Query: 241 DTDGDGALSEAEAQALLSGDTQTDATSFYDRVWAAIRDKYRSEALPTDLPAPSAPDLTEP 300 DTDGDGALSEAEAQALLSGDTQTDATSFYDRVWAAIRDKYRSEALPTDLPAPSAPDLTEP Sbjct: 241 DTDGDGALSEAEAQALLSGDTQTDATSFYDRVWAAIRDKYRSEALPTDLPAPSAPDLTEP 300 Query: 301 KEEQPPVPSSPTEEEEEEEEEEEEEAEEEEEEEDSEEAPPPLSPPQPASPAEEDKMPPYD 360 KEEQPPVPSSPTEEEEEEEEEEEEEAEEEEEEEDSEEAPPPLSPPQPASPAEEDKMPPYD Sbjct: 301 KEEQPPVPSSPTEEEEEEEEEEEEEAEEEEEEEDSEEAPPPLSPPQPASPAEEDKMPPYD 360 Query: 361 EQTQAFIDAAQEARNKFEEAERSLKDMEESIRNLEQEISFDFGPNGEFAYLYSQCYELTT 420 EQTQAFIDAAQEARNKFEEAERSLKDMEESIRNLEQEISFDFGPNGEFAYLYSQCYELTT Sbjct: 361 EQTQAFIDAAQEARNKFEEAERSLKDMEESIRNLEQEISFDFGPNGEFAYLYSQCYELTT 420 Query: 421 NEYVYRLCPFKLVSQKPKLGGSPTSLGTWGSWIGPDHDKFSAMKYEQGTGCWQGPNRSTT 480 NEYVYRLCPFKLVSQKPKLGGSPTSLGTWGSWIGPDHDKFSAMKYEQGTGCWQGPNRSTT Sbjct: 421 NEYVYRLCPFKLVSQKPKLGGSPTSLGTWGSWIGPDHDKFSAMKYEQGTGCWQGPNRSTT 480 Query: 481 VRLLCGKETMVTSTTEPSRCEYLMELMTPAACPEPPPEAPTEDDHDEL 528 VRLLCGKETMVTSTTEPSRCEYLMELMTPAACPEPPPEAPTEDDHDEL Sbjct: 481 VRLLCGKETMVTSTTEPSRCEYLMELMTPAACPEPPPEAPTEDDHDEL 528 >gi|48255891 protein kinase C substrate 80K-H isoform 2 [Homo sapiens] Length = 525 Score = 1069 bits (2765), Expect = 0.0 Identities = 519/528 (98%), Positives = 520/528 (98%), Gaps = 3/528 (0%) Query: 1 MLLPLLLLLPMCWAVEVKRPRGVSLTNHHFYDESKPFTCLDGSATIPFDQVNDDYCDCKD 60 MLLPLLLLLPMCWAVEVKRPRGVSLTNHHFYDESKPFTCLDGSATIPFDQVNDDYCDCKD Sbjct: 1 MLLPLLLLLPMCWAVEVKRPRGVSLTNHHFYDESKPFTCLDGSATIPFDQVNDDYCDCKD 60 Query: 61 GSDEPGTAACPNGSFHCTNTGYKPLYIPSNRVNDGVCDCCDGTDEYNSGVICENTCKEKG 120 GSDEPGTAACPNGSFHCTNTGYKPLYIPSNRVNDGVCDCCDGTDEYNSGVICENTCKEKG Sbjct: 61 GSDEPGTAACPNGSFHCTNTGYKPLYIPSNRVNDGVCDCCDGTDEYNSGVICENTCKEKG 120 Query: 121 RKERESLQQMAEVTREGFRLKKILIEDWKKAREEKQKKLIELQAGKKSLEDQVEMLRTVK 180 RKERESLQQMAEVTREGFRLKKILIEDWKKAREEKQKKLIELQAGKKSLEDQVEMLRTVK Sbjct: 121 RKERESLQQMAEVTREGFRLKKILIEDWKKAREEKQKKLIELQAGKKSLEDQVEMLRTVK 180 Query: 181 EEAEKPEREAKEQHQKLWEEQLAAAKAQQEQELAADAFKELDDDMDGTVSVTELQTHPEL 240 EEAEKPEREAKEQHQKLWEEQLAAAKAQQEQELAADAFKELDDDMDGTVSVTELQTHPEL Sbjct: 181 EEAEKPEREAKEQHQKLWEEQLAAAKAQQEQELAADAFKELDDDMDGTVSVTELQTHPEL 240 Query: 241 DTDGDGALSEAEAQALLSGDTQTDATSFYDRVWAAIRDKYRSEALPTDLPAPSAPDLTEP 300 DTDGDGALSEAEAQALLSGDTQTDATSFYDRVWAAIRDKYRSEALPTDLPAPSAPDLTEP Sbjct: 241 DTDGDGALSEAEAQALLSGDTQTDATSFYDRVWAAIRDKYRSEALPTDLPAPSAPDLTEP 300 Query: 301 KEEQPPVPSSPTEEEEEEEEEEEEEAEEEEEEEDSEEAPPPLSPPQPASPAEEDKMPPYD 360 KEEQPPVPSSPTEEEEEEEEEEEEEAEEEEEEEDSE P+PASPAEEDKMPPYD Sbjct: 301 KEEQPPVPSSPTEEEEEEEEEEEEEAEEEEEEEDSEVQG---EQPKPASPAEEDKMPPYD 357 Query: 361 EQTQAFIDAAQEARNKFEEAERSLKDMEESIRNLEQEISFDFGPNGEFAYLYSQCYELTT 420 EQTQAFIDAAQEARNKFEEAERSLKDMEESIRNLEQEISFDFGPNGEFAYLYSQCYELTT Sbjct: 358 EQTQAFIDAAQEARNKFEEAERSLKDMEESIRNLEQEISFDFGPNGEFAYLYSQCYELTT 417 Query: 421 NEYVYRLCPFKLVSQKPKLGGSPTSLGTWGSWIGPDHDKFSAMKYEQGTGCWQGPNRSTT 480 NEYVYRLCPFKLVSQKPKLGGSPTSLGTWGSWIGPDHDKFSAMKYEQGTGCWQGPNRSTT Sbjct: 418 NEYVYRLCPFKLVSQKPKLGGSPTSLGTWGSWIGPDHDKFSAMKYEQGTGCWQGPNRSTT 477 Query: 481 VRLLCGKETMVTSTTEPSRCEYLMELMTPAACPEPPPEAPTEDDHDEL 528 VRLLCGKETMVTSTTEPSRCEYLMELMTPAACPEPPPEAPTEDDHDEL Sbjct: 478 VRLLCGKETMVTSTTEPSRCEYLMELMTPAACPEPPPEAPTEDDHDEL 525 >gi|84043963 eukaryotic translation initiation factor 5B [Homo sapiens] Length = 1220 Score = 65.5 bits (158), Expect = 1e-10 Identities = 65/246 (26%), Positives = 111/246 (45%), Gaps = 40/246 (16%) Query: 118 EKGRKERESLQQMAEVTREGFR--LKKILIEDWKKAREEKQ--KKLIELQAGKKSLEDQV 173 EK KE+E + ++ T + + L K+ E+ ++ REE++ K+L EL+A +K E Sbjct: 324 EKEEKEKEKKKGPSKATVKAMQEALAKLKEEEERQKREEEERIKRLEELEAKRKEEE--- 380 Query: 174 EMLRTVKEEAEKPEREAKEQHQKLWEEQLAAAKAQQEQELAADAFKELDDDMDGTVSVTE 233 R +E+ E+ +++ KE+ ++L +E K+Q+E A+A +L V V Sbjct: 381 ---RLEQEKRERKKQKEKERKERLKKEGKLLTKSQREARARAEATLKLLQAQG--VEVPS 435 Query: 234 LQTHPELDTDGDGALSEAEAQALLSGDTQTDATSFYDRVWAAIRDKYRSEALPTDLPAPS 293 + P+ + E + + + ++ S + AA+ + + P P Sbjct: 436 KDSLPK-----KRPIYEDKKRKKIPQQLESKEVSESMELCAAVEVMEQGVPEKEETPPPV 490 Query: 294 APDLTEPKEE-----------------------QPPVPSSPTEEEEEEEEEEEEEAEEEE 330 P+ E E+ V +P EEEEEEEEEEE+E EEE Sbjct: 491 EPEEEEDTEDAGLDDWEAMASDEETEKVEGNKVHIEVKENPEEEEEEEEEEEEDEESEEE 550 Query: 331 EEEDSE 336 EEE+ E Sbjct: 551 EEEEGE 556 Score = 63.2 bits (152), Expect = 6e-10 Identities = 68/305 (22%), Positives = 141/305 (46%), Gaps = 25/305 (8%) Query: 122 KERESLQQMAEVTREGFRLKKILIEDWKKAREEKQKKLIELQAG--KKSLEDQVEMLRTV 179 +E+ AE EG + KK D KK + EK++K E + G K +++ E L + Sbjct: 296 EEKAETPTAAEDDNEGDKKKK----DKKKKKGEKEEKEKEKKKGPSKATVKAMQEALAKL 351 Query: 180 KEEAEKPEREAKEQHQKLWEEQLAAAKAQQEQ------ELAADAFKELDDDM--DGTVSV 231 KEE E+ +RE +E+ ++L E+L A + ++E+ E KE + + +G + + Sbjct: 352 KEEEERQKREEEERIKRL--EELEAKRKEEERLEQEKRERKKQKEKERKERLKKEGKL-L 408 Query: 232 TELQTHPELDTDGDGALSEAEAQALLSGDTQTDATSFY-DRVWAAIRDKYRSEALPTDLP 290 T+ Q + L +A+ + S D+ Y D+ I + S+ + + Sbjct: 409 TKSQREARARAEATLKLLQAQGVEVPSKDSLPKKRPIYEDKKRKKIPQQLESKEVSESME 468 Query: 291 APSAPDLTE---PKEEQPPVPSSPTEEEEEEE----EEEEEEAEEEEEEEDSEEAPPPLS 343 +A ++ E P++E+ P P P EEE+ E+ + E ++EE E+ + + + Sbjct: 469 LCAAVEVMEQGVPEKEETPPPVEPEEEEDTEDAGLDDWEAMASDEETEKVEGNKVHIEVK 528 Query: 344 PPQPASPAEEDKMPPYDEQTQAFIDAAQEARNKFEEAERSLKDMEESIRNLEQEISFDFG 403 EE++ +E + + + ++ +E + + D ++S + L+++ S + Sbjct: 529 ENPEEEEEEEEEEEEDEESEEEEEEEGESEGSEGDEEDEKVSDEKDSGKTLDKKPSKEMS 588 Query: 404 PNGEF 408 + E+ Sbjct: 589 SDSEY 593 Score = 44.3 bits (103), Expect = 3e-04 Identities = 55/262 (20%), Positives = 103/262 (39%), Gaps = 16/262 (6%) Query: 145 IEDWKKAREEKQKKLIELQAGKKSLEDQVEMLRTVKEEAEKPEREAKEQHQKLWEEQLAA 204 +ED ++ K +E+ +G +D ++ + K +A+K ++ + E+ Sbjct: 116 LEDKDSKSKKTAKPKVEMYSGSDDDDDFNKLPKKAKGKAQKSNKKWDGSEED--EDNSKK 173 Query: 205 AKAQQEQELAADAFKELDDDMDGTVSVTELQTHP-----ELDTDGDGALSEAEAQALLSG 259 K + + ++ E D+ + + Q + E + D A + + A Sbjct: 174 IKERSRINSSGESGDESDEFLQSRKGQKKNQKNKPGPNIESGNEDDDASFKIKTVAQKKA 233 Query: 260 DTQTDATSFYDRVWAAIRDKYRSEALPTDLPAPSAPDLTEPKEEQPPVPSSPTEEE---- 315 + + D A +R E L T S ++ K E+ V S T + Sbjct: 234 EKKERERKKRDEEKAKLRKLKEKEELETGKKDQSKQKESQRKFEEETVKSKVTVDTGVIP 293 Query: 316 EEEEEEEEEEAEEEEEEEDSEEAPPPLSPPQPASPAEEDKMPPYDEQTQAFIDAAQEARN 375 EE+ E A E++ E D ++ + +E K P ++A + A QEA Sbjct: 294 ASEEKAETPTAAEDDNEGDKKKKDKKKKKGEKEEKEKEKKKGP----SKATVKAMQEALA 349 Query: 376 KF-EEAERSLKDMEESIRNLEQ 396 K EE ER ++ EE I+ LE+ Sbjct: 350 KLKEEEERQKREEEERIKRLEE 371 >gi|221219020 NYD-SP11 protein [Homo sapiens] Length = 2873 Score = 65.1 bits (157), Expect = 2e-10 Identities = 73/298 (24%), Positives = 136/298 (45%), Gaps = 37/298 (12%) Query: 117 KEKGRKERESLQQMAEVTREGFRLKKILIEDWKKAREEKQ--KKLIELQAGKKSLEDQVE 174 ++ + R+ +++ +++E +L KIL K R+E++ ++ I++ K++L + Sbjct: 2050 RKLAKASRKLIKKRESLSKEPAKLNKILKALQKLTRDERKLTQEEIKMTKMKRALFVKER 2109 Query: 175 MLRTVKEEAEKPEREAKEQHQKLWEEQLAAAKAQQEQELAADAFKELDDDMDGTVSVTEL 234 L + + + E + E+ +L +++ A+ Q++ LA + ++ + T ++L Sbjct: 2110 RLSIEQSKLDIKEWDFSEKRSELTKDEKKLARKQRK--LANKMRRMINKEEKMTEEESKL 2167 Query: 235 -QTHPE--LDTDGDGALSEAEAQALLS-----------GDTQTDATSFYDRVWAAIRDKY 280 + H E LD + +G + E E L GD + F +V +++ Sbjct: 2168 ARKHSEVILDDEEEGGIEEEEVIPFLKRRWRKRKEAKRGDKPKE--KFSSQVDEVESEEH 2225 Query: 281 RSEALPTDLPAPSAPDLTEPKEEQPPVPSSPTEEEEEEEEEEEEEAEEEEEEEDSEEAPP 340 SE + + L + E+Q + S EE EEEEE EEEE EEEEE EE Sbjct: 2226 FSEEMES---------LLDELEKQESLSSEEEEEREEEEEREEEEVREEEEERKEEEE-- 2274 Query: 341 PLSPPQPASPAEEDKMPPYDEQTQAFIDAAQEARNKFEEAERSLKDME-ESIRNLEQE 397 + EE+K E+ + + QE FEE E + + E ES+ + E+E Sbjct: 2275 --GEEKQVEKEEEEKKKKKKEKKK---EEVQEKEEVFEEKEEIMSEEETESLSDEEEE 2327 Score = 46.2 bits (108), Expect = 7e-05 Identities = 63/288 (21%), Positives = 114/288 (39%), Gaps = 41/288 (14%) Query: 117 KEKGRKERESLQQMAEVTREGFRLKKILIEDWKKAREEKQKKLIELQAGKKSLEDQVEML 176 KE+ K+ E + EV+REG EEK++++ E Q + ++++ + Sbjct: 1534 KEQQYKDEEEVTLEEEVSREG---------------EEKEQQVTEEQ---RHIQEEHKWA 1575 Query: 177 RTVKEEAEKPEREAKEQHQKLWEEQLAAAK----AQQEQELAADAFKELDDDMDGTVSVT 232 R ++ A ++ A+E+ + EE+ A + AQ+E++LA K DD + Sbjct: 1576 RIHRKRARAEKKRAQEERKLAQEEEKLAQEERQLAQEERKLAQAYVKITQDDRE------ 1629 Query: 233 ELQTHPELDTDGDGALSEAEAQALLSGDTQTDATSFYDRVWAAIRDKYRSEALPTDLPAP 292 +G ++ E G+ + + + K+ A + A Sbjct: 1630 --------MAQAEGKFAQKEETLAQRGEKLSQEAEKLAQKRKKLAKKWEKVAREEEKLAK 1681 Query: 293 SAPDLTEPKE-EQPPVPSSPTEEEEEEEEEEEEEAEEEEEEEDSEEAPPPLSPPQPASPA 351 L E K V P E+ + +E+E E EE E D EE LS + Sbjct: 1682 KGGKLAEVKNILAQKVEELPQREQNLDWQEKELAQELEELEWDMEE----LSWKEEELNQ 1737 Query: 352 EEDKMPPYDEQTQAFIDAAQEARNKFEEAERSLKDMEESIRNLEQEIS 399 EE K+ ++ +A R K E E L EE + +++++ Sbjct: 1738 EEGKLVEEKKKLAEEEEALAWQREKLSEEETKLAQEEELLIQEKEKLA 1785 Score = 38.9 bits (89), Expect = 0.012 Identities = 62/299 (20%), Positives = 115/299 (38%), Gaps = 52/299 (17%) Query: 133 VTREGFRLKKILIED----WKKARE-----------EKQKKLIELQAGKKSLEDQVEMLR 177 VT+E R K+++ + KKAR+ +K KK+I L+ G ++ ++ Sbjct: 1332 VTQEVIRHKEVMPREEEQAQKKARDMLGLEETQVILKKGKKVIFLEPGNVTMGKEIS--- 1388 Query: 178 TVKEEAEKPEREAKEQHQKLWEEQLAAAKAQQEQELAADAFKELDDDMDGTVSVTELQTH 237 K+E +K +++ +Q +K +++ K ++E ++ D + V E+ T Sbjct: 1389 --KKEEKKTFQKSPKQGRKAVQKERKVGKIKREMT---------KEERDMSEEVEEMATL 1437 Query: 238 PELDTDGDGALSEAEAQALLSG-----DTQTDATSFYDRVWAAIRDKYRSEALPTDLPAP 292 E +G L E D + W A ++++ L + Sbjct: 1438 EEKVVKQEGKLVMIERTPSWQDWKKAWDEWKQVHGETRKSWKAWKEEWEKRLLQEEEKLH 1497 Query: 293 SAPDLTEPKEEQPPVPSSPTEEE--------------EEEEEEEEEEAEEEEEEEDSEEA 338 A + P+EE EE E++ ++EEE EEE + EE Sbjct: 1498 QAGEKLSPEEEMLQEDKKLKWEEWKQVWENMLSSKSKEQQYKDEEEVTLEEEVSREGEEK 1557 Query: 339 PPPLSPPQPASPAEEDKMPPYDEQTQAFIDAAQEARNKFEEAERSLKDMEESIRNLEQE 397 ++ Q E + ++ +A AQE R +E E+ + + R L QE Sbjct: 1558 EQQVTEEQRHIQEEHKWARIHRKRARAEKKRAQEERKLAQEEEK----LAQEERQLAQE 1612 Score = 38.1 bits (87), Expect = 0.020 Identities = 65/318 (20%), Positives = 117/318 (36%), Gaps = 48/318 (15%) Query: 117 KEKGRKERESLQQMAEVTREGFRLKKILIEDWKKAREEKQKKLIELQAGKKSLEDQVEML 176 +EK + E L E+ +E KK+ E+WK+ E + Q K E++V + Sbjct: 1493 EEKLHQAGEKLSPEEEMLQED---KKLKWEEWKQVWENMLSSKSKEQQYKD--EEEVTLE 1547 Query: 177 RTVKEEAEKPEREAKEQHQKLWEEQLAAA-----------KAQQEQELAADAFKELDDDM 225 V E E+ E++ E+ + + EE A +AQ+E++LA + K ++ Sbjct: 1548 EEVSREGEEKEQQVTEEQRHIQEEHKWARIHRKRARAEKKRAQEERKLAQEEEKLAQEER 1607 Query: 226 DGTVSVTEL-QTHPELDTD------GDGALSEAEAQALLSGDTQTDATSFYDRVWAAIRD 278 +L Q + ++ D +G ++ E G+ + + + Sbjct: 1608 QLAQEERKLAQAYVKITQDDREMAQAEGKFAQKEETLAQRGEKLSQEAEKLAQKRKKLAK 1667 Query: 279 KYRSEALPTDLPAPSAPDLTEPK-------EEQPPVPSSPTEEEEE-------------- 317 K+ A + A L E K EE P + +E+E Sbjct: 1668 KWEKVAREEEKLAKKGGKLAEVKNILAQKVEELPQREQNLDWQEKELAQELEELEWDMEE 1727 Query: 318 ----EEEEEEEEAEEEEEEEDSEEAPPPLSPPQPASPAEEDKMPPYDEQTQAFIDAAQEA 373 EEE +EE + EE++ E L+ + EE K+ +E + + Sbjct: 1728 LSWKEEELNQEEGKLVEEKKKLAEEEEALAWQREKLSEEETKLAQEEELLIQEKEKLAQH 1787 Query: 374 RNKFEEAERSLKDMEESI 391 + K E E L E + Sbjct: 1788 KEKMPEEEERLGRKREQL 1805 Score = 32.0 bits (71), Expect = 1.4 Identities = 70/323 (21%), Positives = 126/323 (39%), Gaps = 64/323 (19%) Query: 117 KEKGRKERESLQQMAE--------VTREGFRLKKILIE------DWKKAREEKQKKLIEL 162 +E ++ER+ +++ E V +EG K ++IE DWKKA +E ++ E Sbjct: 1418 REMTKEERDMSEEVEEMATLEEKVVKQEG---KLVMIERTPSWQDWKKAWDEWKQVHGET 1474 Query: 163 QAGKKSLEDQVEMLRTVKEE-----AEK--PEREAKEQHQKL-WEEQLAAAKAQQEQELA 214 + K+ +++ E +EE EK PE E ++ +KL WEE K E L+ Sbjct: 1475 RKSWKAWKEEWEKRLLQEEEKLHQAGEKLSPEEEMLQEDKKLKWEEW----KQVWENMLS 1530 Query: 215 ADAFKELDDDMDGTVSVTELQTHPELDTDGDGALSEAEAQALLSGDTQTDATSFYDRVWA 274 + + ++ D + E+ E+ +G+ E E Q T+ + WA Sbjct: 1531 SKSKEQQYKDEE------EVTLEEEVSREGE----EKEQQV-----TEEQRHIQEEHKWA 1575 Query: 275 AIRDKYRSEALPTDLPAPSAPDLTEPKEEQPPVPSSPTEEEEEEEEEEEEEAEEEEEEED 334 I K R+ A E K Q + +EEE+ +EE + +EE Sbjct: 1576 RIHRK-RARA--------------EKKRAQ-----EERKLAQEEEKLAQEERQLAQEERK 1615 Query: 335 SEEAPPPLSPPQPASPAEEDKMPPYDEQTQAFIDAAQEARNKFEEAERSLKDMEESIRNL 394 +A ++ E K +E + + K + + L E + Sbjct: 1616 LAQAYVKITQDDREMAQAEGKFAQKEETLAQRGEKLSQEAEKLAQKRKKLAKKWEKVARE 1675 Query: 395 EQEISFDFGPNGEFAYLYSQCYE 417 E++++ G E + +Q E Sbjct: 1676 EEKLAKKGGKLAEVKNILAQKVE 1698 Score = 30.0 bits (66), Expect = 5.4 Identities = 21/102 (20%), Positives = 54/102 (52%) Query: 113 ENTCKEKGRKERESLQQMAEVTREGFRLKKILIEDWKKAREEKQKKLIELQAGKKSLEDQ 172 E +E+ +E++ ++ E ++ KK +++ ++ EEK++ + E + S E++ Sbjct: 2267 EERKEEEEGEEKQVEKEEEEKKKKKKEKKKEEVQEKEEVFEEKEEIMSEEETESLSDEEE 2326 Query: 173 VEMLRTVKEEAEKPEREAKEQHQKLWEEQLAAAKAQQEQELA 214 E +++EE ++ + K++ Q +EQ + +E+ L+ Sbjct: 2327 EEESCSLEEEVDREKEILKKEKQFKLQEQRRKSLRGRERVLS 2368 >gi|16332372 cell division cycle 2-like 1 (PITSLRE proteins) isoform 9 [Homo sapiens] Length = 771 Score = 63.5 bits (153), Expect = 4e-10 Identities = 73/284 (25%), Positives = 119/284 (41%), Gaps = 26/284 (9%) Query: 117 KEKGRKERESLQQMAEVTREGFRLKKILIEDWKKARE-EKQKKLIELQAGKKSLEDQVEM 175 K++ RKE++ + + E RE R K+ E K RE E+QK+ + + D++E Sbjct: 101 KDEKRKEKKHAR-VKEKEREHERRKRHREEQDKARREWERQKRREMAREHSRRERDRLEQ 159 Query: 176 LRTVKEEAEKPEREAKEQHQKLWEEQLAAAKAQQEQ---ELAADAFKELDDDMDGTVSVT 232 L +E K + KEQ ++ E+ A + ++ + E++A + + +D V + Sbjct: 160 LERKRERERKMREQQKEQREQKERERRAEERRKEREARREVSAH-HRTMREDYSDKVKAS 218 Query: 233 ELQTHP-----ELDTDGDGALSEAEAQALLSGDTQTDATSFYDRVWAAIRDKYRSEALPT 287 P E GDG E + + D +D I D R + Sbjct: 219 HWSRSPPRPPRERFELGDGRKPVKE-EKMEERDLLSDLQD--------ISDSERKTSSAE 269 Query: 288 DLPAPSAPDLTEPKEEQPPVPSSPTEEEEEEEEEEEEEAEEEEEEEDSEEAPPPLSPPQP 347 A S E +EE+ + EE EEEEEEEE EEEE +SEEA Q Sbjct: 270 SSSAESGSGSEEEEEEEEEEEEEGSTSEESEEEEEEEEEEEEETGSNSEEA-----SEQS 324 Query: 348 ASPAEEDKMPPYDEQTQAFIDAAQEARNKFEEAERSLKDMEESI 391 A E++M DE+ + ++F+ ++ EE + Sbjct: 325 AEEVSEEEMSE-DEERENENHLLVVPESRFDRDSGESEEAEEEV 367 Score = 48.9 bits (115), Expect = 1e-05 Identities = 67/315 (21%), Positives = 122/315 (38%), Gaps = 25/315 (7%) Query: 149 KKAREEKQKKLIELQAGKKSLEDQVEMLRTVKEEAEKPEREAKEQHQ--KLWEEQLAAAK 206 K ++ +K+ + + +K E + ++ + E E+ +R +EQ + + WE Q Sbjct: 86 KPPQQMSRKEKVHHRKDEKRKEKKHARVKEKEREHERRKRHREEQDKARREWERQKRREM 145 Query: 207 AQQEQELAADAFKELDDDMDGTVSVTELQTHP----ELDTDGDGALSEAEAQALLSGDTQ 262 A++ D ++L+ + + E Q E + + E EA+ +S + Sbjct: 146 AREHSRRERDRLEQLERKRERERKMREQQKEQREQKERERRAEERRKEREARREVSAHHR 205 Query: 263 TDATSFYDRVWAA--IRDKYRSEALPTDLPAPSAPDLTEPKEEQP------PVPSSPTEE 314 T + D+V A+ R R +L P E EE+ + S + Sbjct: 206 TMREDYSDKVKASHWSRSPPRPPRERFELGDGRKPVKEEKMEERDLLSDLQDISDSERKT 265 Query: 315 EEEEEEEEEEEAEEEEEEEDSEEAPPPLSPPQPASPAEEDKMPPYDEQTQAFIDAAQEAR 374 E E + EEEEE+ EE S + + EE++ +E +A++++ Sbjct: 266 SSAESSSAESGSGSEEEEEEEEEEEEEGSTSEESEEEEEEEEEEEEETGSNSEEASEQSA 325 Query: 375 NKFEEAERSLKDMEESIRNL----EQEISFDFGPNGEFAYLYS----QCYELTTNEYV-- 424 + E E S + E+ +L E D G + E Q LT +YV Sbjct: 326 EEVSEEEMSEDEERENENHLLVVPESRFDRDSGESEEAEEEVGEGTPQSSALTEGDYVPD 385 Query: 425 -YRLCPFKLVSQKPK 438 L P +L + PK Sbjct: 386 SPALSPIELKQELPK 400 Score = 30.0 bits (66), Expect = 5.4 Identities = 31/144 (21%), Positives = 53/144 (36%), Gaps = 6/144 (4%) Query: 51 VNDDYCDCKDGSDEPGTAACPNGSFHCTNTGYKPLYIPSNRVNDGVCDCCDGTDEYNSGV 110 + +DY D S + P G KP+ D + D D +D Sbjct: 207 MREDYSDKVKASHWSRSPPRPPRERFELGDGRKPVKEEKMEERDLLSDLQDISDSERKTS 266 Query: 111 ICENTCKEKGRKERESLQQMAEVTREGFRLKKILIEDWKKAREEKQKKLIELQAGKKSLE 170 E++ E G E ++ E EG ++ E+ ++ EE++ +A ++S E Sbjct: 267 SAESSSAESGSGSEEEEEEEEEEEEEGSTSEESEEEEEEEEEEEEETGSNSEEASEQSAE 326 Query: 171 DQVEMLRTVKEEAEKPEREAKEQH 194 + E EE + E E H Sbjct: 327 EVSE------EEMSEDEERENENH 344 >gi|16332362 cell division cycle 2-like 1 (PITSLRE proteins) isoform 4 [Homo sapiens] Length = 737 Score = 63.5 bits (153), Expect = 4e-10 Identities = 73/284 (25%), Positives = 119/284 (41%), Gaps = 26/284 (9%) Query: 117 KEKGRKERESLQQMAEVTREGFRLKKILIEDWKKARE-EKQKKLIELQAGKKSLEDQVEM 175 K++ RKE++ + + E RE R K+ E K RE E+QK+ + + D++E Sbjct: 67 KDEKRKEKKHAR-VKEKEREHERRKRHREEQDKARREWERQKRREMAREHSRRERDRLEQ 125 Query: 176 LRTVKEEAEKPEREAKEQHQKLWEEQLAAAKAQQEQ---ELAADAFKELDDDMDGTVSVT 232 L +E K + KEQ ++ E+ A + ++ + E++A + + +D V + Sbjct: 126 LERKRERERKMREQQKEQREQKERERRAEERRKEREARREVSAH-HRTMREDYSDKVKAS 184 Query: 233 ELQTHP-----ELDTDGDGALSEAEAQALLSGDTQTDATSFYDRVWAAIRDKYRSEALPT 287 P E GDG E + + D +D I D R + Sbjct: 185 HWSRSPPRPPRERFELGDGRKPVKE-EKMEERDLLSDLQD--------ISDSERKTSSAE 235 Query: 288 DLPAPSAPDLTEPKEEQPPVPSSPTEEEEEEEEEEEEEAEEEEEEEDSEEAPPPLSPPQP 347 A S E +EE+ + EE EEEEEEEE EEEE +SEEA Q Sbjct: 236 SSSAESGSGSEEEEEEEEEEEEEGSTSEESEEEEEEEEEEEEETGSNSEEA-----SEQS 290 Query: 348 ASPAEEDKMPPYDEQTQAFIDAAQEARNKFEEAERSLKDMEESI 391 A E++M DE+ + ++F+ ++ EE + Sbjct: 291 AEEVSEEEMSE-DEERENENHLLVVPESRFDRDSGESEEAEEEV 333 Score = 48.9 bits (115), Expect = 1e-05 Identities = 67/315 (21%), Positives = 122/315 (38%), Gaps = 25/315 (7%) Query: 149 KKAREEKQKKLIELQAGKKSLEDQVEMLRTVKEEAEKPEREAKEQHQ--KLWEEQLAAAK 206 K ++ +K+ + + +K E + ++ + E E+ +R +EQ + + WE Q Sbjct: 52 KPPQQMSRKEKVHHRKDEKRKEKKHARVKEKEREHERRKRHREEQDKARREWERQKRREM 111 Query: 207 AQQEQELAADAFKELDDDMDGTVSVTELQTHP----ELDTDGDGALSEAEAQALLSGDTQ 262 A++ D ++L+ + + E Q E + + E EA+ +S + Sbjct: 112 AREHSRRERDRLEQLERKRERERKMREQQKEQREQKERERRAEERRKEREARREVSAHHR 171 Query: 263 TDATSFYDRVWAA--IRDKYRSEALPTDLPAPSAPDLTEPKEEQP------PVPSSPTEE 314 T + D+V A+ R R +L P E EE+ + S + Sbjct: 172 TMREDYSDKVKASHWSRSPPRPPRERFELGDGRKPVKEEKMEERDLLSDLQDISDSERKT 231 Query: 315 EEEEEEEEEEEAEEEEEEEDSEEAPPPLSPPQPASPAEEDKMPPYDEQTQAFIDAAQEAR 374 E E + EEEEE+ EE S + + EE++ +E +A++++ Sbjct: 232 SSAESSSAESGSGSEEEEEEEEEEEEEGSTSEESEEEEEEEEEEEEETGSNSEEASEQSA 291 Query: 375 NKFEEAERSLKDMEESIRNL----EQEISFDFGPNGEFAYLYS----QCYELTTNEYV-- 424 + E E S + E+ +L E D G + E Q LT +YV Sbjct: 292 EEVSEEEMSEDEERENENHLLVVPESRFDRDSGESEEAEEEVGEGTPQSSALTEGDYVPD 351 Query: 425 -YRLCPFKLVSQKPK 438 L P +L + PK Sbjct: 352 SPALSPIELKQELPK 366 Score = 30.0 bits (66), Expect = 5.4 Identities = 31/144 (21%), Positives = 53/144 (36%), Gaps = 6/144 (4%) Query: 51 VNDDYCDCKDGSDEPGTAACPNGSFHCTNTGYKPLYIPSNRVNDGVCDCCDGTDEYNSGV 110 + +DY D S + P G KP+ D + D D +D Sbjct: 173 MREDYSDKVKASHWSRSPPRPPRERFELGDGRKPVKEEKMEERDLLSDLQDISDSERKTS 232 Query: 111 ICENTCKEKGRKERESLQQMAEVTREGFRLKKILIEDWKKAREEKQKKLIELQAGKKSLE 170 E++ E G E ++ E EG ++ E+ ++ EE++ +A ++S E Sbjct: 233 SAESSSAESGSGSEEEEEEEEEEEEEGSTSEESEEEEEEEEEEEEETGSNSEEASEQSAE 292 Query: 171 DQVEMLRTVKEEAEKPEREAKEQH 194 + E EE + E E H Sbjct: 293 EVSE------EEMSEDEERENENH 310 >gi|148763345 cell division cycle 2-like 2 isoform 4 [Homo sapiens] Length = 770 Score = 62.0 bits (149), Expect = 1e-09 Identities = 73/284 (25%), Positives = 118/284 (41%), Gaps = 27/284 (9%) Query: 117 KEKGRKERESLQQMAEVTREGFRLKKILIEDWKKARE-EKQKKLIELQAGKKSLEDQVEM 175 K++ RKE+ ++ E RE R K+ E K RE E+QK+ + + D++E Sbjct: 101 KDEKRKEKWKHARVKE--REHERRKRHREEQDKARREWERQKRREMAREHSRRERDRLEQ 158 Query: 176 LRTVKEEAEKPEREAKEQHQKLWEEQLAAAKAQQEQ---ELAADAFKELDDDMDGTVSVT 232 L +E K + KEQ ++ E+ A + ++ + E++A + + +D V + Sbjct: 159 LERKRERERKMREQQKEQREQKERERRAEERRKEREARREVSAH-HRTMREDYSDKVKAS 217 Query: 233 ELQTHP-----ELDTDGDGALSEAEAQALLSGDTQTDATSFYDRVWAAIRDKYRSEALPT 287 P E GDG E + + D +D I D R + Sbjct: 218 HWSRSPPRPPRERFELGDGRKPVKE-EKMEERDLLSDLQD--------ISDSERKTSSAE 268 Query: 288 DLPAPSAPDLTEPKEEQPPVPSSPTEEEEEEEEEEEEEAEEEEEEEDSEEAPPPLSPPQP 347 A S E +EE+ + EE EEEEEEEE EEEE +SEEA Q Sbjct: 269 SSSAESGSGSEEEEEEEEEEEEEGSTSEESEEEEEEEEEEEEETGSNSEEA-----SEQS 323 Query: 348 ASPAEEDKMPPYDEQTQAFIDAAQEARNKFEEAERSLKDMEESI 391 A E++M DE+ + ++F+ ++ EE + Sbjct: 324 AEEVSEEEMSE-DEERENENHLLVVPESRFDRDSGESEEAEEEV 366 Score = 49.3 bits (116), Expect = 9e-06 Identities = 78/360 (21%), Positives = 136/360 (37%), Gaps = 52/360 (14%) Query: 107 NSGVICENTCKEKGRKERESL-----QQMAEVTREGFRLKKILIEDWKKAREEKQKKLIE 161 NS E++ +++G +E +SL QQM+ + R + E WK AR ++++ Sbjct: 64 NSPYRREDSMEDRG-EEDDSLAIKPPQQMSRKEKVHHRKDEKRKEKWKHARVKERE---- 118 Query: 162 LQAGKKSLEDQVEMLRTVKEEAEKPEREAKEQHQKLWEEQLAAAKAQQEQELAADAFKEL 221 E K RE +++ ++ WE Q A++ D ++L Sbjct: 119 -------------------HERRKRHREEQDKARREWERQKRREMAREHSRRERDRLEQL 159 Query: 222 DDDMDGTVSVTELQTHP----ELDTDGDGALSEAEAQALLSGDTQTDATSFYDRVWAA-- 275 + + + E Q E + + E EA+ +S +T + D+V A+ Sbjct: 160 ERKRERERKMREQQKEQREQKERERRAEERRKEREARREVSAHHRTMREDYSDKVKASHW 219 Query: 276 IRDKYRSEALPTDLPAPSAPDLTEPKEEQP------PVPSSPTEEEEEEEEEEEEEAEEE 329 R R +L P E EE+ + S + E E + E Sbjct: 220 SRSPPRPPRERFELGDGRKPVKEEKMEERDLLSDLQDISDSERKTSSAESSSAESGSGSE 279 Query: 330 EEEEDSEEAPPPLSPPQPASPAEEDKMPPYDEQTQAFIDAAQEARNKFEEAERSLKDMEE 389 EEEE+ EE S + + EE++ +E +A++++ + E E S + E Sbjct: 280 EEEEEEEEEEEEGSTSEESEEEEEEEEEEEEETGSNSEEASEQSAEEVSEEEMSEDEERE 339 Query: 390 SIRNL----EQEISFDFGPNGEFAYLYS----QCYELTTNEYV---YRLCPFKLVSQKPK 438 + +L E D G + E Q LT +YV L P +L + PK Sbjct: 340 NENHLLVVPESRFDRDSGESEEAEEEVGEGTPQSSALTEGDYVPDSPALLPIELKQELPK 399 Score = 30.0 bits (66), Expect = 5.4 Identities = 31/144 (21%), Positives = 53/144 (36%), Gaps = 6/144 (4%) Query: 51 VNDDYCDCKDGSDEPGTAACPNGSFHCTNTGYKPLYIPSNRVNDGVCDCCDGTDEYNSGV 110 + +DY D S + P G KP+ D + D D +D Sbjct: 206 MREDYSDKVKASHWSRSPPRPPRERFELGDGRKPVKEEKMEERDLLSDLQDISDSERKTS 265 Query: 111 ICENTCKEKGRKERESLQQMAEVTREGFRLKKILIEDWKKAREEKQKKLIELQAGKKSLE 170 E++ E G E ++ E EG ++ E+ ++ EE++ +A ++S E Sbjct: 266 SAESSSAESGSGSEEEEEEEEEEEEEGSTSEESEEEEEEEEEEEEETGSNSEEASEQSAE 325 Query: 171 DQVEMLRTVKEEAEKPEREAKEQH 194 + E EE + E E H Sbjct: 326 EVSE------EEMSEDEERENENH 343 >gi|4505257 moesin [Homo sapiens] Length = 577 Score = 62.0 bits (149), Expect = 1e-09 Identities = 75/311 (24%), Positives = 133/311 (42%), Gaps = 46/311 (14%) Query: 86 YIPSNRVNDGVCDCCDGTDEYNSGVICENTCKEKGRKERESLQQMAEVTREGFRLKKI-- 143 Y P R+N + C G E + + + +QQM RE K++ Sbjct: 270 YAPRLRINKRILALCMGNHELYM---------RRRKPDTIEVQQMKAQAREEKHQKQMER 320 Query: 144 -LIEDWKKARE--EKQKKLIELQAGKKSLEDQVEMLRTVKEEAEKPEREAKEQHQKLWEE 200 ++E+ KK RE EK+K+ IE + E+ +E L+ ++E+ +K ++E +EQ ++ E Sbjct: 321 AMLENEKKKREMAEKEKEKIE-----REKEELMERLKQIEEQTKKAQQELEEQTRRALEL 375 Query: 201 QLAAAKAQQEQELAADAFKELDDDMDGTVSVTELQTHPELDTDGDGALSEAEAQALLSGD 260 + +AQ E E A +E ++ + + + Q T AL AE A +S Sbjct: 376 EQERKRAQSEAEKLAKERQEAEEAKEALLQASRDQK----KTQEQLALEMAELTARIS-- 429 Query: 261 TQTDATSFYDRVWAAIRDKYRSEALPTDLPAPSA-PDLTEPKEEQPPVPSSP--TEEEEE 317 Q + R K SEA+ A DL + + E S+P E E Sbjct: 430 -QLEMA----------RQKKESEAVEWQQKAQMVQEDLEKTRAELKTAMSTPHVAEPAEN 478 Query: 318 EEEEEEEEAEEEEEEEDSEEAPPPLSPPQPASPAEEDKMPPYDEQTQAFIDA-AQEARNK 376 E++E++E E + ++ S + + AE+ +E+ Q + A E N Sbjct: 479 EQDEQDENGAEASADLRADAMAKDRSEEERTTEAEK------NERVQKHLKALTSELANA 532 Query: 377 FEEAERSLKDM 387 +E++++ DM Sbjct: 533 RDESKKTANDM 543 Score = 35.0 bits (79), Expect = 0.17 Identities = 20/76 (26%), Positives = 40/76 (52%), Gaps = 3/76 (3%) Query: 315 EEEEEEEEEEEAEEEEEEEDSEEAPPPLSPPQPASPAEEDKMPPYDEQTQAFIDAAQEAR 374 E E+++ E E E+E+ E + EE L + + + ++ +EQT+ ++ QE + Sbjct: 324 ENEKKKREMAEKEKEKIEREKEELMERLKQIEEQTKKAQQEL---EEQTRRALELEQERK 380 Query: 375 NKFEEAERSLKDMEES 390 EAE+ K+ +E+ Sbjct: 381 RAQSEAEKLAKERQEA 396 >gi|16332364 cell division cycle 2-like 1 (PITSLRE proteins) isoform 5 [Homo sapiens] Length = 748 Score = 61.6 bits (148), Expect = 2e-09 Identities = 74/289 (25%), Positives = 117/289 (40%), Gaps = 30/289 (10%) Query: 117 KEKGRKERESLQ-----QMAEVTREGFRLKKILIEDWKKARE-EKQKKLIELQAGKKSLE 170 KEK R S + ++ E RE R K+ E K RE E+QK+ + + Sbjct: 72 KEKRRHRSHSAEGGKHARVKEKEREHERRKRHREEQDKARREWERQKRREMAREHSRRER 131 Query: 171 DQVEMLRTVKEEAEKPEREAKEQHQKLWEEQLAAAKAQQEQ---ELAADAFKELDDDMDG 227 D++E L +E K + KEQ ++ E+ A + ++ + E++A + + +D Sbjct: 132 DRLEQLERKRERERKMREQQKEQREQKERERRAEERRKEREARREVSAH-HRTMREDYSD 190 Query: 228 TVSVTELQTHP-----ELDTDGDGALSEAEAQALLSGDTQTDATSFYDRVWAAIRDKYRS 282 V + P E GDG E + + D +D I D R Sbjct: 191 KVKASHWSRSPPRPPRERFELGDGRKPVKE-EKMEERDLLSDLQD--------ISDSERK 241 Query: 283 EALPTDLPAPSAPDLTEPKEEQPPVPSSPTEEEEEEEEEEEEEAEEEEEEEDSEEAPPPL 342 + A S E +EE+ + EE EEEEEEEE EEEE +SEEA Sbjct: 242 TSSAESSSAESGSGSEEEEEEEEEEEEEGSTSEESEEEEEEEEEEEEETGSNSEEA---- 297 Query: 343 SPPQPASPAEEDKMPPYDEQTQAFIDAAQEARNKFEEAERSLKDMEESI 391 Q A E++M DE+ + ++F+ ++ EE + Sbjct: 298 -SEQSAEEVSEEEMSE-DEERENENHLLVVPESRFDRDSGESEEAEEEV 344 Score = 52.0 bits (123), Expect = 1e-06 Identities = 79/360 (21%), Positives = 143/360 (39%), Gaps = 40/360 (11%) Query: 107 NSGVICENTCKEKGRKERESL-----QQMAEVTREGFRLKKILIEDWKKAREEKQKKLIE 161 NS E++ +++G +E +SL QQM+ R +K+ +K +E+++ + Sbjct: 30 NSPYRREDSMEDRG-EEDDSLAIKPPQQMS-------RKEKVHHRKDEKRKEKRRHRSHS 81 Query: 162 LQAGKKSLEDQVEMLRTVKEEAEKPEREAKEQHQKLWEEQLAAAKAQQEQELAADAFKEL 221 + GK + + E + E K RE +++ ++ WE Q A++ D ++L Sbjct: 82 AEGGKHARVKEKER----EHERRKRHREEQDKARREWERQKRREMAREHSRRERDRLEQL 137 Query: 222 DDDMDGTVSVTELQTHP----ELDTDGDGALSEAEAQALLSGDTQTDATSFYDRVWAA-- 275 + + + E Q E + + E EA+ +S +T + D+V A+ Sbjct: 138 ERKRERERKMREQQKEQREQKERERRAEERRKEREARREVSAHHRTMREDYSDKVKASHW 197 Query: 276 IRDKYRSEALPTDLPAPSAPDLTEPKEEQP------PVPSSPTEEEEEEEEEEEEEAEEE 329 R R +L P E EE+ + S + E E + E Sbjct: 198 SRSPPRPPRERFELGDGRKPVKEEKMEERDLLSDLQDISDSERKTSSAESSSAESGSGSE 257 Query: 330 EEEEDSEEAPPPLSPPQPASPAEEDKMPPYDEQTQAFIDAAQEARNKFEEAERSLKDMEE 389 EEEE+ EE S + + EE++ +E +A++++ + E E S + E Sbjct: 258 EEEEEEEEEEEEGSTSEESEEEEEEEEEEEEETGSNSEEASEQSAEEVSEEEMSEDEERE 317 Query: 390 SIRNL----EQEISFDFGPNGEFAYLYS----QCYELTTNEYV---YRLCPFKLVSQKPK 438 + +L E D G + E Q LT +YV L P +L + PK Sbjct: 318 NENHLLVVPESRFDRDSGESEEAEEEVGEGTPQSSALTEGDYVPDSPALSPIELKQELPK 377 Score = 30.0 bits (66), Expect = 5.4 Identities = 31/144 (21%), Positives = 53/144 (36%), Gaps = 6/144 (4%) Query: 51 VNDDYCDCKDGSDEPGTAACPNGSFHCTNTGYKPLYIPSNRVNDGVCDCCDGTDEYNSGV 110 + +DY D S + P G KP+ D + D D +D Sbjct: 184 MREDYSDKVKASHWSRSPPRPPRERFELGDGRKPVKEEKMEERDLLSDLQDISDSERKTS 243 Query: 111 ICENTCKEKGRKERESLQQMAEVTREGFRLKKILIEDWKKAREEKQKKLIELQAGKKSLE 170 E++ E G E ++ E EG ++ E+ ++ EE++ +A ++S E Sbjct: 244 SAESSSAESGSGSEEEEEEEEEEEEEGSTSEESEEEEEEEEEEEEETGSNSEEASEQSAE 303 Query: 171 DQVEMLRTVKEEAEKPEREAKEQH 194 + E EE + E E H Sbjct: 304 EVSE------EEMSEDEERENENH 321 >gi|16332358 cell division cycle 2-like 1 (PITSLRE proteins) isoform 2 [Homo sapiens] Length = 782 Score = 61.6 bits (148), Expect = 2e-09 Identities = 74/289 (25%), Positives = 117/289 (40%), Gaps = 30/289 (10%) Query: 117 KEKGRKERESLQ-----QMAEVTREGFRLKKILIEDWKKARE-EKQKKLIELQAGKKSLE 170 KEK R S + ++ E RE R K+ E K RE E+QK+ + + Sbjct: 106 KEKRRHRSHSAEGGKHARVKEKEREHERRKRHREEQDKARREWERQKRREMAREHSRRER 165 Query: 171 DQVEMLRTVKEEAEKPEREAKEQHQKLWEEQLAAAKAQQEQ---ELAADAFKELDDDMDG 227 D++E L +E K + KEQ ++ E+ A + ++ + E++A + + +D Sbjct: 166 DRLEQLERKRERERKMREQQKEQREQKERERRAEERRKEREARREVSAH-HRTMREDYSD 224 Query: 228 TVSVTELQTHP-----ELDTDGDGALSEAEAQALLSGDTQTDATSFYDRVWAAIRDKYRS 282 V + P E GDG E + + D +D I D R Sbjct: 225 KVKASHWSRSPPRPPRERFELGDGRKPVKE-EKMEERDLLSDLQD--------ISDSERK 275 Query: 283 EALPTDLPAPSAPDLTEPKEEQPPVPSSPTEEEEEEEEEEEEEAEEEEEEEDSEEAPPPL 342 + A S E +EE+ + EE EEEEEEEE EEEE +SEEA Sbjct: 276 TSSAESSSAESGSGSEEEEEEEEEEEEEGSTSEESEEEEEEEEEEEEETGSNSEEA---- 331 Query: 343 SPPQPASPAEEDKMPPYDEQTQAFIDAAQEARNKFEEAERSLKDMEESI 391 Q A E++M DE+ + ++F+ ++ EE + Sbjct: 332 -SEQSAEEVSEEEMSE-DEERENENHLLVVPESRFDRDSGESEEAEEEV 378 Score = 52.0 bits (123), Expect = 1e-06 Identities = 79/360 (21%), Positives = 143/360 (39%), Gaps = 40/360 (11%) Query: 107 NSGVICENTCKEKGRKERESL-----QQMAEVTREGFRLKKILIEDWKKAREEKQKKLIE 161 NS E++ +++G +E +SL QQM+ R +K+ +K +E+++ + Sbjct: 64 NSPYRREDSMEDRG-EEDDSLAIKPPQQMS-------RKEKVHHRKDEKRKEKRRHRSHS 115 Query: 162 LQAGKKSLEDQVEMLRTVKEEAEKPEREAKEQHQKLWEEQLAAAKAQQEQELAADAFKEL 221 + GK + + E + E K RE +++ ++ WE Q A++ D ++L Sbjct: 116 AEGGKHARVKEKER----EHERRKRHREEQDKARREWERQKRREMAREHSRRERDRLEQL 171 Query: 222 DDDMDGTVSVTELQTHP----ELDTDGDGALSEAEAQALLSGDTQTDATSFYDRVWAA-- 275 + + + E Q E + + E EA+ +S +T + D+V A+ Sbjct: 172 ERKRERERKMREQQKEQREQKERERRAEERRKEREARREVSAHHRTMREDYSDKVKASHW 231 Query: 276 IRDKYRSEALPTDLPAPSAPDLTEPKEEQP------PVPSSPTEEEEEEEEEEEEEAEEE 329 R R +L P E EE+ + S + E E + E Sbjct: 232 SRSPPRPPRERFELGDGRKPVKEEKMEERDLLSDLQDISDSERKTSSAESSSAESGSGSE 291 Query: 330 EEEEDSEEAPPPLSPPQPASPAEEDKMPPYDEQTQAFIDAAQEARNKFEEAERSLKDMEE 389 EEEE+ EE S + + EE++ +E +A++++ + E E S + E Sbjct: 292 EEEEEEEEEEEEGSTSEESEEEEEEEEEEEEETGSNSEEASEQSAEEVSEEEMSEDEERE 351 Query: 390 SIRNL----EQEISFDFGPNGEFAYLYS----QCYELTTNEYV---YRLCPFKLVSQKPK 438 + +L E D G + E Q LT +YV L P +L + PK Sbjct: 352 NENHLLVVPESRFDRDSGESEEAEEEVGEGTPQSSALTEGDYVPDSPALSPIELKQELPK 411 Score = 30.0 bits (66), Expect = 5.4 Identities = 31/144 (21%), Positives = 53/144 (36%), Gaps = 6/144 (4%) Query: 51 VNDDYCDCKDGSDEPGTAACPNGSFHCTNTGYKPLYIPSNRVNDGVCDCCDGTDEYNSGV 110 + +DY D S + P G KP+ D + D D +D Sbjct: 218 MREDYSDKVKASHWSRSPPRPPRERFELGDGRKPVKEEKMEERDLLSDLQDISDSERKTS 277 Query: 111 ICENTCKEKGRKERESLQQMAEVTREGFRLKKILIEDWKKAREEKQKKLIELQAGKKSLE 170 E++ E G E ++ E EG ++ E+ ++ EE++ +A ++S E Sbjct: 278 SAESSSAESGSGSEEEEEEEEEEEEEGSTSEESEEEEEEEEEEEEETGSNSEEASEQSAE 337 Query: 171 DQVEMLRTVKEEAEKPEREAKEQH 194 + E EE + E E H Sbjct: 338 EVSE------EEMSEDEERENENH 355 >gi|239756241 PREDICTED: golgi autoantigen, golgin subfamily a-like [Homo sapiens] Length = 899 Score = 61.2 bits (147), Expect = 2e-09 Identities = 62/294 (21%), Positives = 131/294 (44%), Gaps = 34/294 (11%) Query: 113 ENTCKEKGRKERESLQQMAEVTREGFRLKKILIEDWKKA--REEKQKKLIELQAGKKSLE 170 E+ E+ K R+ Q+M + R++K E KK +EEK ++ ++ +K + Sbjct: 543 EDQMWEQEEKMRDQEQKMWDQEE---RMEKKTQEQEKKTWDQEEKMREEERMREREKKMR 599 Query: 171 DQVEMLRTVKEEAEKPEREAKEQHQKLWEEQLAAAKAQQEQELAADAFKELDDDMDGTVS 230 ++ EM+R +E+ ++ E + +EQ +K+WE++ + +++ + E ++ M Sbjct: 600 EEEEMMREQEEKMQEQEEKMQEQEEKMWEQEEKMQEQEEKMWEQEEKMWEQEEKMWEQQR 659 Query: 231 VTE----LQTHPELDTDGDGALSEAE--AQALLSGDTQTDATSFYDRVWAAIRDKYRSEA 284 + E L H ++ E + Q + TQ +D ++K R E Sbjct: 660 LPEQKEKLWEHEKMQEQEKMQEQEEKIWEQEKMEKKTQEQEKKTWD------QEKMREE- 712 Query: 285 LPTDLPAPSAPDLTEPKEEQPPVPSSPTEEEEEEEEEEEEEAEEEEEEEDSEEAPPPLSP 344 + E +++ E+EE+ +E+EE+ E+EEE + EE Sbjct: 713 ----------ESMREREKKMREEEEMMREQEEKMQEQEEKMQEQEEEMWEQEEK----MW 758 Query: 345 PQPASPAEEDKMPPYDEQTQAFIDAAQEARNKFEEAERSLKDMEESIRNLEQEI 398 Q E+ ++P +++ + + + + K E E ++D EE +R E+++ Sbjct: 759 EQEEKMWEQQRLP--EQKEKLWEHEKMQEQEKIWEQEEKMRDQEEKMRGQEEKM 810 Score = 57.4 bits (137), Expect = 3e-08 Identities = 56/299 (18%), Positives = 129/299 (43%), Gaps = 21/299 (7%) Query: 117 KEKGRKERESLQQMAEVTREGFRLKKILIEDWKKAREEKQKKLIELQAGKKSLEDQVEM- 175 +EK +K+ E++ + E + RL + + W++ + ++Q++ I Q K + DQ EM Sbjct: 470 EEKMQKQEENMWEQEEKEWQQQRLPEQKEKLWEQEKMQEQEEKIWEQEEK--IRDQEEMW 527 Query: 176 -----------LRTVKEEAEKPEREAKEQHQKLWEEQLAAAKAQQEQELAA-DAFKELDD 223 +R +++ + E + ++Q QK+W+++ K QEQE D +++ + Sbjct: 528 GQEKKMWRQEKMREQEDQMWEQEEKMRDQEQKMWDQEERMEKKTQEQEKKTWDQEEKMRE 587 Query: 224 DMDGTVSVTELQTHPELDTDGDGALSEAE----AQALLSGDTQTDATSFYDRVWAAIRDK 279 + +++ E+ + + + E E Q + + +++W Sbjct: 588 EERMREREKKMREEEEMMREQEEKMQEQEEKMQEQEEKMWEQEEKMQEQEEKMWEQEEKM 647 Query: 280 YRSEALPTDLPAPSAPDLTEPKEEQPPVPSSPTEEEEEEEEEEEEEAEEEEEEEDSEEAP 339 + E + P+ E E + +E+EE+ E+E+ E++ +E++ + Sbjct: 648 WEQEEKMWE--QQRLPEQKEKLWEHEKMQEQEKMQEQEEKIWEQEKMEKKTQEQEKKTWD 705 Query: 340 PPLSPPQPASPAEEDKMPPYDEQTQAFIDAAQEARNKFEEAERSLKDMEESIRNLEQEI 398 + + E KM +E + + QE K +E E + + EE + E+++ Sbjct: 706 QEKMREEESMREREKKMREEEEMMREQEEKMQEQEEKMQEQEEEMWEQEEKMWEQEEKM 764 Score = 53.9 bits (128), Expect = 4e-07 Identities = 58/306 (18%), Positives = 125/306 (40%), Gaps = 25/306 (8%) Query: 113 ENTCKEKGRKERESLQQMAEVTREGFRLKKILIEDWKKAREEKQK-------------KL 159 E +E+ K E ++M E + +R ++ L E K+ RE++QK +L Sbjct: 347 EEQMQEQEEKMWEQEEKMREQEEKMWRQEERLWEQEKQMREQEQKMRDQEERMWEQDERL 406 Query: 160 IELQAGKKSLEDQVEMLRTVKEEAEKPEREAK--EQHQKLWEEQL---AAAKAQQEQELA 214 E + + E E + ++EE + E+E K +Q +K+ EE+ K ++E+E Sbjct: 407 REKEERMREQEKMWEQVEKMREEKKMQEQEKKTRDQEEKMQEEERIREREKKMREEEETM 466 Query: 215 ADAFKELDDDMDGTVSVTELQTHPELDTDGDGALSEAEAQALLSGD--TQTDATSFYDRV 272 + +++ + E + + + L E E Q + + + Sbjct: 467 REQEEKMQKQEENMWEQEEKEWQQQRLPEQKEKLWEQEKMQEQEEKIWEQEEKIRDQEEM 526 Query: 273 WAAIRDKYRSEALPTDLPAPSAPDLTEPKEEQPPVPSSPTEEEEEEEEEEEEEAEEEEEE 332 W + +R E + + E +E+ ++EE E++ +E+ ++ ++ Sbjct: 527 WGQEKKMWRQEKM-----REQEDQMWEQEEKMRDQEQKMWDQEERMEKKTQEQEKKTWDQ 581 Query: 333 EDSEEAPPPLSPPQPASPAEEDKMPPYDEQTQAFIDAAQEARNKFEEAERSLKDMEESIR 392 E+ + + EE+ M +E+ Q + QE K E E +++ EE + Sbjct: 582 EEKMREEERMREREKKMREEEEMMREQEEKMQEQEEKMQEQEEKMWEQEEKMQEQEEKMW 641 Query: 393 NLEQEI 398 E+++ Sbjct: 642 EQEEKM 647 Score = 53.5 bits (127), Expect = 5e-07 Identities = 65/322 (20%), Positives = 136/322 (42%), Gaps = 48/322 (14%) Query: 117 KEKGRKERESLQQMAEVTREGFRLKKILIEDWKKAREEKQKKLIE--LQAGKKSLEDQVE 174 KE+ +E+E + + E RE +K + E KK R++++K E ++ +K + ++ E Sbjct: 409 KEERMREQEKMWEQVEKMRE----EKKMQEQEKKTRDQEEKMQEEERIREREKKMREEEE 464 Query: 175 MLRTVKEEAEKPE-------------REAKEQHQKLWEEQLAAAKAQQEQELAADAFKEL 221 +R +E+ +K E + EQ +KLWE++ K Q+++E + +++ Sbjct: 465 TMREQEEKMQKQEENMWEQEEKEWQQQRLPEQKEKLWEQE----KMQEQEEKIWEQEEKI 520 Query: 222 DDDMDGTVSVTELQTHPELDTDGDGALSEAE-----------AQALLSGDTQTDATSFYD 270 D + ++ ++ D + E + + TQ +D Sbjct: 521 RDQEEMWGQEKKMWRQEKMREQEDQMWEQEEKMRDQEQKMWDQEERMEKKTQEQEKKTWD 580 Query: 271 -----RVWAAIRDKYRSEALPTDLPAPSAPDLTEPKEEQPPVPSSPTEEEEEEEEEEEEE 325 R +R++ + ++ + E +E+ E+EE+ +E+EE+ Sbjct: 581 QEEKMREEERMREREKKMREEEEMMREQEEKMQEQEEKMQEQEEKMWEQEEKMQEQEEKM 640 Query: 326 AEEEEEEEDSEEA--PPPLSPPQPASPAEEDKMPPYD--EQTQAFIDAAQEARNKFEEAE 381 E+EE+ + EE P Q E +KM + ++ + I ++ K +E E Sbjct: 641 WEQEEKMWEQEEKMWEQQRLPEQKEKLWEHEKMQEQEKMQEQEEKIWEQEKMEKKTQEQE 700 Query: 382 RSLKDM-----EESIRNLEQEI 398 + D EES+R E+++ Sbjct: 701 KKTWDQEKMREEESMREREKKM 722 Score = 47.8 bits (112), Expect = 3e-05 Identities = 63/294 (21%), Positives = 123/294 (41%), Gaps = 28/294 (9%) Query: 123 ERESLQ-QMAEVTREGFRLKKILIE-DWKKAREEKQKKLIELQAGKKSLEDQVEMLRTVK 180 E+ +Q + E+ R+ R K +L + +EE ++ EL+ +K + Q E + + Sbjct: 240 EKSEIQLNVKELKRKLERAKFLLPQVQTNTLQEEMWRQEEELREQEKKIRKQEEKMWRQE 299 Query: 181 EEAEKPEREAKEQHQKLWEEQLAAAKAQQEQELAADAFKELDDDMDGTVSVTELQTHPEL 240 E + E + +EQ +K+W ++ +QE+EL + KEL + + ++Q E Sbjct: 300 ERLREQEGKMREQEEKMWRQE--KRLREQEKEL-REQEKELREQKELREQEEQMQEQEEK 356 Query: 241 DTDGDGALSEAE-----------AQALLSGDTQTDATSFYDRVW---AAIRDKYRSEALP 286 + + + E E Q + + +R+W +R+K Sbjct: 357 MWEQEEKMREQEEKMWRQEERLWEQEKQMREQEQKMRDQEERMWEQDERLREK-EERMRE 415 Query: 287 TDLPAPSAPDLTEPKEEQPPVPSSPTEEEEEEEEE--EEEEAEEEEEEEDSEEAPPPLSP 344 + + E K+ Q + +EE+ +EEE E E + EEEE E + Sbjct: 416 QEKMWEQVEKMREEKKMQEQEKKTRDQEEKMQEEERIREREKKMREEEETMREQEEKMQK 475 Query: 345 PQPASPAEEDKMPPYDEQTQAFIDAAQE--ARNKFEEAERSLKDMEESIRNLEQ 396 + +E+K + Q Q + ++ + K +E E + + EE IR+ E+ Sbjct: 476 QEENMWEQEEK----EWQQQRLPEQKEKLWEQEKMQEQEEKIWEQEEKIRDQEE 525 Score = 44.7 bits (104), Expect = 2e-04 Identities = 61/288 (21%), Positives = 119/288 (41%), Gaps = 38/288 (13%) Query: 117 KEKGRKERESLQQMAEVTREGFRLKKILIEDWKKAREEKQKKLIELQAGKKSLEDQVEML 176 +EK +E++ L++ E +E ++ + E +K RE+++K + ++ L +Q + + Sbjct: 333 QEKELREQKELREQEEQMQEQ---EEKMWEQEEKMREQEEK----MWRQEERLWEQEKQM 385 Query: 177 RTVKEEAEKPEREAKEQHQKL--WEEQLAAAKAQQEQELAADAFKELDDDMDGTVSVTEL 234 R +++ E EQ ++L EE++ + EQ K++ + T E Sbjct: 386 REQEQKMRDQEERMWEQDERLREKEERMREQEKMWEQVEKMREEKKMQEQEKKTRDQEEK 445 Query: 235 QTHPELDTDGDGALSEAEAQALLSGDTQTDATSFYDRVWAAIRDKYRSEALPTDLPAPSA 294 E + + + E E + + + +W +++ + LP Sbjct: 446 MQEEERIREREKKMREEEE---TMREQEEKMQKQEENMWEQEEKEWQQQRLP-------- 494 Query: 295 PDLTEPKEEQPPVPSSPTEEEEEEEEEEEEEAEEEEEEEDSEE--APPPLSPPQPASPAE 352 E KE+ E+E+ +E+EE+ E+EE+ D EE Q + Sbjct: 495 ----EQKEK--------LWEQEKMQEQEEKIWEQEEKIRDQEEMWGQEKKMWRQEKMREQ 542 Query: 353 EDKMPPYDE----QTQAFIDAAQEARNKFEEAERSLKDMEESIRNLEQ 396 ED+M +E Q Q D + K +E E+ D EE +R E+ Sbjct: 543 EDQMWEQEEKMRDQEQKMWDQEERMEKKTQEQEKKTWDQEEKMREEER 590 Score = 35.4 bits (80), Expect = 0.13 Identities = 20/85 (23%), Positives = 42/85 (49%), Gaps = 3/85 (3%) Query: 314 EEEEEEEEEEEEAEEEEEEEDSEEAPPPLSPPQPASPAEEDKMPPYDEQTQAFIDAAQEA 373 E+E+E E+E+E E++E + EE + + +E+KM +E+ + E Sbjct: 325 EQEKELREQEKELREQKELREQEEQ---MQEQEEKMWEQEEKMREQEEKMWRQEERLWEQ 381 Query: 374 RNKFEEAERSLKDMEESIRNLEQEI 398 + E E+ ++D EE + ++ + Sbjct: 382 EKQMREQEQKMRDQEERMWEQDERL 406 Score = 35.4 bits (80), Expect = 0.13 Identities = 20/86 (23%), Positives = 40/86 (46%) Query: 313 EEEEEEEEEEEEEAEEEEEEEDSEEAPPPLSPPQPASPAEEDKMPPYDEQTQAFIDAAQE 372 +E E+E+E E+ E E+EE +E + + +E+KM +E+ +E Sbjct: 328 KELREQEKELREQKELREQEEQMQEQEEKMWEQEEKMREQEEKMWRQEERLWEQEKQMRE 387 Query: 373 ARNKFEEAERSLKDMEESIRNLEQEI 398 K + E + + +E +R E+ + Sbjct: 388 QEQKMRDQEERMWEQDERLREKEERM 413 Score = 33.5 bits (75), Expect = 0.49 Identities = 19/85 (22%), Positives = 45/85 (52%), Gaps = 3/85 (3%) Query: 117 KEKGRKERESLQQMAEVTREGFRLKKILIEDWKKAREEKQKKLIELQAGKKSLEDQVEML 176 +E+ ++ E + + E E RL + + W+ + ++Q+K+ E + + + DQ E + Sbjct: 747 EEEMWEQEEKMWEQEEKMWEQQRLPEQKEKLWEHEKMQEQEKIWEQE---EKMRDQEEKM 803 Query: 177 RTVKEEAEKPEREAKEQHQKLWEEQ 201 R +E+ E + + Q +K+W ++ Sbjct: 804 RGQEEKMRGQEEKMRGQEEKMWGQE 828 >gi|155030232 proline, glutamic acid and leucine rich protein 1 [Homo sapiens] Length = 1130 Score = 61.2 bits (147), Expect = 2e-09 Identities = 42/124 (33%), Positives = 57/124 (45%), Gaps = 13/124 (10%) Query: 283 EALPTDLPAPSAPDLTEPKEEQPPVPSSPTEEEEEEEEEEEEEAEEEEEEEDSEEAPPPL 342 + +P P P E + SS EEEEEEEEEEEEE EEEEEE+ EE Sbjct: 859 QLVPEGTPGGGGPPALEEDLTVININSSDEEEEEEEEEEEEEEEEEEEEEDFEEE----- 913 Query: 343 SPPQPASPAEEDKMPPYDEQTQAFIDAAQEARNKFEEAERSLKDMEESIRNLEQEISFDF 402 EE+ +E+ + F + +E + EE E ++ EE LE+ +F Sbjct: 914 ------EEDEEEYFEEEEEEEEEFEEEFEEEEGELEEEEE--EEDEEEEEELEEVEDLEF 965 Query: 403 GPNG 406 G G Sbjct: 966 GTAG 969 Score = 54.3 bits (129), Expect = 3e-07 Identities = 53/227 (23%), Positives = 98/227 (43%), Gaps = 18/227 (7%) Query: 146 EDWKKAREEKQKKLIELQAGKKSLEDQVEMLRTVKEEAEKPEREAKEQHQKLWEEQLAAA 205 E+ ++ EE++++ E + ++ ED+ E +EE E+ E E +E+ +L EE+ Sbjct: 891 EEEEEEEEEEEEEEEEEEDFEEEEEDEEEYFEEEEEEEEEFEEEFEEEEGELEEEE---- 946 Query: 206 KAQQEQELAADAFKELDDDMDGTVSVTELQTHPELDTDGDGALSEAEAQALLSGDTQTDA 265 ++E E + +E++D GT + P T AL E+ + + + + Sbjct: 947 --EEEDEEEEEELEEVEDLEFGTAGGEVEEGAPPPPTLPP-ALPPPESPPKVQPEPEPEP 1003 Query: 266 TSFYDRVWAAIRDKYRSEALPTDLPAPSAPDLTEPKEEQPPVPSSPTEEEEEEEEEEEEE 325 + ++ ++ PT P +E + P P +E EEE Sbjct: 1004 GLLLEVEEPGTEEERGADTAPTLAPEALPSQGEVEREGESPAAGPPPQELVEEEPSAPPT 1063 Query: 326 AEEEEEEEDSEEAPPPLSPPQPASPAEEDKMPPYDEQTQAFIDAAQE 372 EEE E+ S++ PP P +PAEE+ +T+ +A QE Sbjct: 1064 LLEEETEDGSDKVQPP-----PETPAEEEM------ETETEAEALQE 1099 Score = 49.3 bits (116), Expect = 9e-06 Identities = 66/263 (25%), Positives = 102/263 (38%), Gaps = 42/263 (15%) Query: 110 VICENTCKEKGRKERESLQQMAEVTREGFRLKKILIEDWKKAREEKQKKLIELQAGKKSL 169 VI N+ E+ +E E ++ E E ED+++ E++++ E + ++ Sbjct: 880 VININSSDEEEEEEEEEEEEEEEEEEEE--------EDFEEEEEDEEEYFEEEEEEEEEF 931 Query: 170 EDQVEMLRTVKEEAEKPEREAKEQHQKLWE-EQLAAAKAQQEQELAADAFKELDDDMDGT 228 E++ E EE E E E +E+ ++L E E L A E E A L + Sbjct: 932 EEEFEEEEGELEEEE--EEEDEEEEEELEEVEDLEFGTAGGEVEEGAPPPPTLPPALPPP 989 Query: 229 VSVTELQTHPELDTDGDGALSEAEAQALLSGDTQTDATSFYDRVWAAIRDKYRSEALPTD 288 S ++Q PE + G L E E A + + + R P Sbjct: 990 ESPPKVQPEPEPEP---GLLLEVEEPGTEEERGADTAPTLAPEALPSQGEVEREGESPAA 1046 Query: 289 LPAP---------SAPDLTEPKEE------QPPVPSSPTEEEEEEEEEEEEEAEEEEEE- 332 P P + P L E + E QPP P +P EEE E E E E E+E+++ Sbjct: 1047 GPPPQELVEEEPSAPPTLLEEETEDGSDKVQPP-PETPAEEEMETETEAEALQEKEQDDT 1105 Query: 333 -----------EDSEEAPPPLSP 344 D E+ PPP P Sbjct: 1106 AAMLADFIDCPPDDEKPPPPTEP 1128 Score = 44.7 bits (104), Expect = 2e-04 Identities = 55/237 (23%), Positives = 85/237 (35%), Gaps = 45/237 (18%) Query: 180 KEEAEKPEREAKEQHQKLWEEQLAAAKAQQEQELAADAFKELDDDMDGTVSVTELQTHPE 239 +EE E+ E E +E+ + EE+ + +E+E + F+E ++ +G + E E Sbjct: 893 EEEEEEEEEEEEEEEEDFEEEEEDEEEYFEEEEEEEEEFEEEFEEEEGELEEEE----EE 948 Query: 240 LDTDGDGALSEAEAQALLSGDTQTDATSFYDRVWAAIRDKYRSEALPTDLPAPSAPDLTE 299 D + + L E E + + + E P P P+ P Sbjct: 949 EDEEEEEELEEVEDLEFGTAGGEVE------------------EGAP---PPPTLPPALP 987 Query: 300 PKEEQPPVPSSPTEEEEEEEEEEEEEAEEEEE-----------------EEDSEEAPPPL 342 P E P V P E E E EE EEE E + E P Sbjct: 988 PPESPPKVQPEP-EPEPGLLLEVEEPGTEEERGADTAPTLAPEALPSQGEVEREGESPAA 1046 Query: 343 SPPQPASPAEEDKMPP--YDEQTQAFIDAAQEARNKFEEAERSLKDMEESIRNLEQE 397 PP EE PP +E+T+ D Q E E + E+++ EQ+ Sbjct: 1047 GPPPQELVEEEPSAPPTLLEEETEDGSDKVQPPPETPAEEEMETETEAEALQEKEQD 1103 Score = 34.7 bits (78), Expect = 0.22 Identities = 33/127 (25%), Positives = 47/127 (37%), Gaps = 40/127 (31%) Query: 290 PAPSAPDLTEPKEEQPPVPSSPTEEEEEEEEEEEEEAEEEEEEEDSEEAPPPLSPPQPAS 349 P P AP T P PPVP+ +EE E+ AP PL PP P Sbjct: 808 PPPIAP--TGPPTASPPVPA-------------------KEEPEELPAAPGPLPPPPPPP 846 Query: 350 PAEED--KMPP-----------------YDEQTQAFIDAAQEARNKFEEAERSLKDMEES 390 P +PP ++ T I+++ E + EE E ++ EE Sbjct: 847 PPVPGPVTLPPPQLVPEGTPGGGGPPALEEDLTVININSSDEEEEEEEEEEEEEEEEEEE 906 Query: 391 IRNLEQE 397 + E+E Sbjct: 907 EEDFEEE 913 >gi|222418637 golgi autoantigen, golgin subfamily a-like [Homo sapiens] Length = 750 Score = 60.8 bits (146), Expect = 3e-09 Identities = 56/276 (20%), Positives = 121/276 (43%), Gaps = 18/276 (6%) Query: 122 KERESLQQMAEVTREGFRLKKILIEDWKKAREEKQKKLIELQAGKKSLEDQVEMLRTVKE 181 K RE +++ E ++ +R ++ + E K EEK+++ E+ ++ + +Q E+ R KE Sbjct: 438 KIREQEEKIREQEKKMWRQEEKIHEQEKIREEEKRQEQEEMWRQEEKIHEQEEIWRQ-KE 496 Query: 182 EAEKPEREAKEQHQKLWEEQLAAAKAQQEQELAADAFKELDDDMDGTVSVTELQTHPELD 241 + + E + ++Q +K+W ++ K ++++E + +++ + E+ E Sbjct: 497 KMHEQEEKIRKQEEKVWRQE---EKIREQEEKIREQEEKMWRQEEKIREQEEMWREEEKM 553 Query: 242 TDGDGALSEAEAQALLSGDTQTDATSFYDRVWAAIRDKYRSEALPTDLPAPSAPDLTEPK 301 + + E + Q D++W +K R + + E + Sbjct: 554 HEQEKIWEEEKRQEQ------------EDKMWRQ-EEKIREQEEKVWRQEEKIREQEEKR 600 Query: 302 EEQPPVPSSPTEE-EEEEEEEEEEEAEEEEEEEDSEEAPPPLSPPQPASPAEEDKMPPYD 360 +EQ E+ E+EE+ +E+E + E+EE E + +E+KM + Sbjct: 601 QEQEEKMWKQEEKIREQEEKIQEQEEKIREQEEKIREQEEMTQEQEEKMGEQEEKMCEQE 660 Query: 361 EQTQAFIDAAQEARNKFEEAERSLKDMEESIRNLEQ 396 E+ Q + K E E+ +++ EE IR E+ Sbjct: 661 EKMQEQEETMWRQEEKIREQEKKIREQEEKIREQEE 696 Score = 53.1 bits (126), Expect = 6e-07 Identities = 59/285 (20%), Positives = 129/285 (45%), Gaps = 35/285 (12%) Query: 117 KEKGRKERESLQQMAEVTREGFRLKKILIEDWK-KAREEKQKKLIELQAGKKSLEDQVEM 175 +EK R++ E + + E RE L++ + E K + +EEK+++ +++ +K E + +M Sbjct: 376 EEKMRRQEEMMWEKEEKIRE---LEEKMHEQEKIREQEEKRQEEEKIREQEKRQEQEAKM 432 Query: 176 LRTVKEEAEKPEREAKEQHQKLWEEQLAAAKAQQEQELAADAFKELDDDMDGTVSVTELQ 235 R +E+ + E + +EQ +K+W ++ K +++++ + ++ ++M E + Sbjct: 433 WRQ-EEKIREQEEKIREQEKKMWRQE---EKIHEQEKIREEEKRQEQEEMWRQ----EEK 484 Query: 236 THPELDTDGDGALSEAEAQALLSGDTQTDATSFYDRVWAAIRDKYRSEALPTDLPAPSAP 295 H + E Q + + ++VW +K R + Sbjct: 485 IHEQ---------EEIWRQKEKMHEQEEKIRKQEEKVWRQ-EEKIREQE----------- 523 Query: 296 DLTEPKEEQPPVPSSPTEEEEEEEEEEEEEAEEEE--EEEDSEEAPPPLSPPQPASPAEE 353 + +EE+ E+EE EEE+ E+E+ EEE +E + + +E Sbjct: 524 EKIREQEEKMWRQEEKIREQEEMWREEEKMHEQEKIWEEEKRQEQEDKMWRQEEKIREQE 583 Query: 354 DKMPPYDEQTQAFIDAAQEARNKFEEAERSLKDMEESIRNLEQEI 398 +K+ +E+ + + QE K + E +++ EE I+ E++I Sbjct: 584 EKVWRQEEKIREQEEKRQEQEEKMWKQEEKIREQEEKIQEQEEKI 628 Score = 50.8 bits (120), Expect = 3e-06 Identities = 57/300 (19%), Positives = 129/300 (43%), Gaps = 16/300 (5%) Query: 113 ENTCKEKGRKERESLQQMAEVTREGFRLKKILIEDWKKAREE--KQKKLI----ELQAGK 166 E +E+ K RE ++M + +KI E+ ++ +EE +Q++ I E+ K Sbjct: 436 EEKIREQEEKIREQEKKMWRQEEKIHEQEKIREEEKRQEQEEMWRQEEKIHEQEEIWRQK 495 Query: 167 KSLEDQVEMLRTVKEEAEKPEREAKEQHQKLWEEQLAAAKAQQEQELAADAFKELDDDMD 226 + + +Q E +R +E+ + E + +EQ +K+ E++ + +++ + ++E ++ M Sbjct: 496 EKMHEQEEKIRKQEEKVWRQEEKIREQEEKIREQEEKMWRQEEKIREQEEMWRE-EEKMH 554 Query: 227 GTVSVTELQTHPELDTD---GDGALSEAEAQALLSGDT----QTDATSFYDRVWAAIRDK 279 + E + E + + + E E + + + +++W +K Sbjct: 555 EQEKIWEEEKRQEQEDKMWRQEEKIREQEEKVWRQEEKIREQEEKRQEQEEKMWKQ-EEK 613 Query: 280 YRSEALPTDLPAPSAPDLTEPKEEQPPVPSSPTEEEEEEEEEE-EEEAEEEEEEEDSEEA 338 R + + E EQ + E+ E+EE+ E+E + +E+EE Sbjct: 614 IREQEEKIQEQEEKIREQEEKIREQEEMTQEQEEKMGEQEEKMCEQEEKMQEQEETMWRQ 673 Query: 339 PPPLSPPQPASPAEEDKMPPYDEQTQAFIDAAQEARNKFEEAERSLKDMEESIRNLEQEI 398 + + +E+K+ +E Q + E K E E +++ EE +R E+++ Sbjct: 674 EEKIREQEKKIREQEEKIREQEEMMQEQEEKMWEQEEKMCEQEEKMQEQEEKMRRQEEKM 733 Score = 45.1 bits (105), Expect = 2e-04 Identities = 49/280 (17%), Positives = 115/280 (41%), Gaps = 33/280 (11%) Query: 117 KEKGRKERESLQQMAEVTREGFRLKKILIEDWKKAREEKQKKLIELQAGKKSLEDQVEML 176 +EK ++ E +Q+ E +E ++ + E +K RE+++K ++ ++ + ++ E + Sbjct: 299 EEKMWRQEEKIQEWEEKIQEQ---EEKIREQEEKIREQEEK----MRRQEEMMWEKEEKM 351 Query: 177 RTVKEEAEKPEREAKEQHQKLWEEQLAAAKAQQEQELAADAFKELDDDMDGTVSVTELQT 236 R +E + E + + Q + +WE++ + ++ + +EL++ M + E + Sbjct: 352 RRQEEMMWEKEEKMRRQEEMMWEKEEKMRRQEEMMWEKEEKIRELEEKMHEQEKIREQEE 411 Query: 237 HPELDTDGDGALSEAEAQALLSGDTQTDATSFYDRVWAAIRDKYRSEALPTDLPAPSAPD 296 + + E +A ++W +K R + Sbjct: 412 KRQEEEKIREQEKRQEQEA---------------KMWRQ-EEKIREQ----------EEK 445 Query: 297 LTEPKEEQPPVPSSPTEEEEEEEEEEEEEAEEEEEEEDSEEAPPPLSPPQPASPAEEDKM 356 + E +++ E+E+ EEE+ +E EE +E+ + + +E+K+ Sbjct: 446 IREQEKKMWRQEEKIHEQEKIREEEKRQEQEEMWRQEEKIHEQEEIWRQKEKMHEQEEKI 505 Query: 357 PPYDEQTQAFIDAAQEARNKFEEAERSLKDMEESIRNLEQ 396 +E+ + +E K E E + EE IR E+ Sbjct: 506 RKQEEKVWRQEEKIREQEEKIREQEEKMWRQEEKIREQEE 545 Score = 36.2 bits (82), Expect = 0.076 Identities = 26/107 (24%), Positives = 48/107 (44%), Gaps = 5/107 (4%) Query: 297 LTEPKEEQPPVPSSPTEEEEEEEEEEEEEAEEEEE-----EEDSEEAPPPLSPPQPASPA 351 L + +EE+ +E EE+ +E+EE+ E+EE EE + + Sbjct: 294 LNQQQEEKMWRQEEKIQEWEEKIQEQEEKIREQEEKIREQEEKMRRQEEMMWEKEEKMRR 353 Query: 352 EEDKMPPYDEQTQAFIDAAQEARNKFEEAERSLKDMEESIRNLEQEI 398 +E+ M +E+ + + E K E + + EE IR LE+++ Sbjct: 354 QEEMMWEKEEKMRRQEEMMWEKEEKMRRQEEMMWEKEEKIRELEEKM 400 >gi|148763347 cell division cycle 2-like 2 isoform 1 [Homo sapiens] Length = 780 Score = 59.3 bits (142), Expect = 8e-09 Identities = 71/277 (25%), Positives = 112/277 (40%), Gaps = 41/277 (14%) Query: 117 KEKGRKERESLQQMAEVTREGFRLKKILIEDWKKAREEKQKKLIELQAGKKSLEDQVEML 176 ++K R+E E Q+ E+ RE R ++ +E ++ RE ++K ++ +K +Q E Sbjct: 139 QDKARREWER-QKRREMAREHSRRERDRLEQLERKRERERK----MREQQKEQREQKERE 193 Query: 177 RTVKEEAEKPE--REAKEQHQKLWEEQLAAAKAQQEQELAADAFKELDDDMDGTVSVTEL 234 R +E ++ E RE H+ + E+ KA +E + DG V E Sbjct: 194 RRAEERRKEREARREVSAHHRTMREDYSDKVKASHWSRSPPRPPRERFELGDGRKPVKE- 252 Query: 235 QTHPELDTDGDGALSEAEAQALLSGDTQTDATSFYDRVWAAIRDKYRSEALPTDLPAPSA 294 + E + LLS D Q I D R + A S Sbjct: 253 --------------EKMEERDLLS-DLQD------------ISDSERKTSSAESSSAESG 285 Query: 295 PDLTEPKEEQPPVPSSPTEEEEEEEEEEEEEAEEEEEEEDSEEAPPPLSPPQPASPAEED 354 E +EE+ + EE EEEEEEEE EEEE +SEEA Q A E+ Sbjct: 286 SGSEEEEEEEEEEEEEGSTSEESEEEEEEEEEEEEETGSNSEEA-----SEQSAEEVSEE 340 Query: 355 KMPPYDEQTQAFIDAAQEARNKFEEAERSLKDMEESI 391 +M DE+ + ++F+ ++ EE + Sbjct: 341 EMSE-DEERENENHLLVVPESRFDRDSGESEEAEEEV 376 Score = 47.8 bits (112), Expect = 3e-05 Identities = 62/282 (21%), Positives = 107/282 (37%), Gaps = 23/282 (8%) Query: 180 KEEAEKPEREAKEQHQKLWEEQLAAAKAQQEQELAADAFKELDDDMDGTVSVTELQTHP- 238 + E K RE +++ ++ WE Q A++ D ++L+ + + E Q Sbjct: 128 EHERRKRHREEQDKARREWERQKRREMAREHSRRERDRLEQLERKRERERKMREQQKEQR 187 Query: 239 ---ELDTDGDGALSEAEAQALLSGDTQTDATSFYDRVWAA--IRDKYRSEALPTDLPAPS 293 E + + E EA+ +S +T + D+V A+ R R +L Sbjct: 188 EQKERERRAEERRKEREARREVSAHHRTMREDYSDKVKASHWSRSPPRPPRERFELGDGR 247 Query: 294 APDLTEPKEEQP------PVPSSPTEEEEEEEEEEEEEAEEEEEEEDSEEAPPPLSPPQP 347 P E EE+ + S + E E + EEEEE+ EE S + Sbjct: 248 KPVKEEKMEERDLLSDLQDISDSERKTSSAESSSAESGSGSEEEEEEEEEEEEEGSTSEE 307 Query: 348 ASPAEEDKMPPYDEQTQAFIDAAQEARNKFEEAERSLKDMEESIRNL----EQEISFDFG 403 + EE++ +E +A++++ + E E S + E+ +L E D G Sbjct: 308 SEEEEEEEEEEEEETGSNSEEASEQSAEEVSEEEMSEDEERENENHLLVVPESRFDRDSG 367 Query: 404 PNGEFAYLYS----QCYELTTNEYV---YRLCPFKLVSQKPK 438 + E Q LT +YV L P +L + PK Sbjct: 368 ESEEAEEEVGEGTPQSSALTEGDYVPDSPALLPIELKQELPK 409 Score = 30.0 bits (66), Expect = 5.4 Identities = 31/144 (21%), Positives = 53/144 (36%), Gaps = 6/144 (4%) Query: 51 VNDDYCDCKDGSDEPGTAACPNGSFHCTNTGYKPLYIPSNRVNDGVCDCCDGTDEYNSGV 110 + +DY D S + P G KP+ D + D D +D Sbjct: 216 MREDYSDKVKASHWSRSPPRPPRERFELGDGRKPVKEEKMEERDLLSDLQDISDSERKTS 275 Query: 111 ICENTCKEKGRKERESLQQMAEVTREGFRLKKILIEDWKKAREEKQKKLIELQAGKKSLE 170 E++ E G E ++ E EG ++ E+ ++ EE++ +A ++S E Sbjct: 276 SAESSSAESGSGSEEEEEEEEEEEEEGSTSEESEEEEEEEEEEEEETGSNSEEASEQSAE 335 Query: 171 DQVEMLRTVKEEAEKPEREAKEQH 194 + E EE + E E H Sbjct: 336 EVSE------EEMSEDEERENENH 353 >gi|16332370 cell division cycle 2-like 1 (PITSLRE proteins) isoform 8 [Homo sapiens] Length = 780 Score = 58.9 bits (141), Expect = 1e-08 Identities = 73/293 (24%), Positives = 119/293 (40%), Gaps = 35/293 (11%) Query: 117 KEKGRKERESLQQMAEVTREGFRLKKILIEDWKKAREEKQKKLIELQAGKKSLE------ 170 K++ RKE++ + + E RE R K+ E K RE +++K E+ E Sbjct: 101 KDEKRKEKKHAR-VKEKEREHERRKRHREEQDKARREWERQKRREMAREHSRRERGNDGV 159 Query: 171 ----DQVEMLRTVKEEAEKPEREAKEQHQKLWEEQLAAAKAQQEQ---ELAADAFKELDD 223 D++E L +E K + KEQ ++ E+ A + ++ + E++A + + + Sbjct: 160 CLFRDRLEQLERKRERERKMREQQKEQREQKERERRAEERRKEREARREVSAH-HRTMRE 218 Query: 224 DMDGTVSVTELQTHP-----ELDTDGDGALSEAEAQALLSGDTQTDATSFYDRVWAAIRD 278 D V + P E GDG E + + D +D I D Sbjct: 219 DYSDKVKASHWSRSPPRPPRERFELGDGRKPVKE-EKMEERDLLSDLQD--------ISD 269 Query: 279 KYRSEALPTDLPAPSAPDLTEPKEEQPPVPSSPTEEEEEEEEEEEEEAEEEEEEEDSEEA 338 R + A S E +EE+ + EE EEEEEEEE EEEE +SEEA Sbjct: 270 SERKTSSAESSSAESGSGSEEEEEEEEEEEEEGSTSEESEEEEEEEEEEEEETGSNSEEA 329 Query: 339 PPPLSPPQPASPAEEDKMPPYDEQTQAFIDAAQEARNKFEEAERSLKDMEESI 391 Q A E++M DE+ + ++F+ ++ EE + Sbjct: 330 -----SEQSAEEVSEEEMSE-DEERENENHLLVVPESRFDRDSGESEEAEEEV 376 Score = 44.3 bits (103), Expect = 3e-04 Identities = 69/314 (21%), Positives = 120/314 (38%), Gaps = 28/314 (8%) Query: 149 KKAREEKQKKLIELQAGKKSLEDQVEMLRTVKEEAEKPERE-AKEQHQKLWEEQLAAAKA 207 +K + K+KK A K E + E + +EE +K RE +++ +++ E + Sbjct: 100 RKDEKRKEKK----HARVKEKEREHERRKRHREEQDKARREWERQKRREMAREHSRRERG 155 Query: 208 QQEQELAADAFKELDDDMDGTVSVTELQTHP----ELDTDGDGALSEAEAQALLSGDTQT 263 L D ++L+ + + E Q E + + E EA+ +S +T Sbjct: 156 NDGVCLFRDRLEQLERKRERERKMREQQKEQREQKERERRAEERRKEREARREVSAHHRT 215 Query: 264 DATSFYDRVWAA--IRDKYRSEALPTDLPAPSAPDLTEPKEEQP------PVPSSPTEEE 315 + D+V A+ R R +L P E EE+ + S + Sbjct: 216 MREDYSDKVKASHWSRSPPRPPRERFELGDGRKPVKEEKMEERDLLSDLQDISDSERKTS 275 Query: 316 EEEEEEEEEEAEEEEEEEDSEEAPPPLSPPQPASPAEEDKMPPYDEQTQAFIDAAQEARN 375 E E + EEEEE+ EE S + + EE++ +E +A++++ Sbjct: 276 SAESSSAESGSGSEEEEEEEEEEEEEGSTSEESEEEEEEEEEEEEETGSNSEEASEQSAE 335 Query: 376 KFEEAERSLKDMEESIRNL----EQEISFDFGPNGEFAYLYS----QCYELTTNEYV--- 424 + E E S + E+ +L E D G + E Q LT +YV Sbjct: 336 EVSEEEMSEDEERENENHLLVVPESRFDRDSGESEEAEEEVGEGTPQSSALTEGDYVPDS 395 Query: 425 YRLCPFKLVSQKPK 438 L P +L + PK Sbjct: 396 PALSPIELKQELPK 409 Score = 37.4 bits (85), Expect = 0.034 Identities = 68/318 (21%), Positives = 123/318 (38%), Gaps = 68/318 (21%) Query: 91 RVNDGVCDCCDGTDEYNSGVICENTCKEKGRKERESLQQMAEVTREGFRLKKILIEDWKK 150 R NDGVC D ++ + K +ER+ +Q E + R ++ E+ +K Sbjct: 154 RGNDGVCLFRDRLEQ----------LERKRERERKMREQQKEQREQKERERR--AEERRK 201 Query: 151 AREEKQKKLIELQAGKKSLEDQVEMLRTVKEEAEKPEREAKEQHQKLWEEQLAAAKAQQE 210 RE +++ + ++ D+V+ + P R +E+ + + + +E Sbjct: 202 EREARREVSAHHRTMREDYSDKVK----ASHWSRSPPRPPRERFELGDGRKPVKEEKMEE 257 Query: 211 QELAADAFKELDDDMDGTVSVTELQTHPELDTDGDGALSEAEAQALLSGDTQTDATSFYD 270 ++L +D L D +S +E +T S AE+ + SG + Sbjct: 258 RDLLSD----LQD-----ISDSERKT------------SSAESSSAESGSGSEEEEE--- 293 Query: 271 RVWAAIRDKYRSEALPTDLPAPSAPDLTEPKEEQPPVPSSPTEEEEEEEEEEEEEAEEEE 330 ++ E T + + E +EE+ S E+ EE EEE +E+EE Sbjct: 294 ------EEEEEEEEGSTSEESEEEEEEEEEEEEETGSNSEEASEQSAEEVSEEEMSEDEE 347 Query: 331 EEE-----------------DSEEAPPPL--SPPQPASPAEEDKMPPYDEQTQAFIDAAQ 371 E +SEEA + PQ ++ E D +P D + I+ Q Sbjct: 348 RENENHLLVVPESRFDRDSGESEEAEEEVGEGTPQSSALTEGDYVP--DSPALSPIELKQ 405 Query: 372 EARNKFEEAERSLKDMEE 389 E K+ A + + +EE Sbjct: 406 EL-PKYLPALQGCRSVEE 422 Score = 30.0 bits (66), Expect = 5.4 Identities = 31/144 (21%), Positives = 53/144 (36%), Gaps = 6/144 (4%) Query: 51 VNDDYCDCKDGSDEPGTAACPNGSFHCTNTGYKPLYIPSNRVNDGVCDCCDGTDEYNSGV 110 + +DY D S + P G KP+ D + D D +D Sbjct: 216 MREDYSDKVKASHWSRSPPRPPRERFELGDGRKPVKEEKMEERDLLSDLQDISDSERKTS 275 Query: 111 ICENTCKEKGRKERESLQQMAEVTREGFRLKKILIEDWKKAREEKQKKLIELQAGKKSLE 170 E++ E G E ++ E EG ++ E+ ++ EE++ +A ++S E Sbjct: 276 SAESSSAESGSGSEEEEEEEEEEEEEGSTSEESEEEEEEEEEEEEETGSNSEEASEQSAE 335 Query: 171 DQVEMLRTVKEEAEKPEREAKEQH 194 + E EE + E E H Sbjct: 336 EVSE------EEMSEDEERENENH 353 >gi|239745089 PREDICTED: golgi autoantigen, golgin subfamily a-like [Homo sapiens] Length = 828 Score = 58.2 bits (139), Expect = 2e-08 Identities = 60/281 (21%), Positives = 117/281 (41%), Gaps = 20/281 (7%) Query: 117 KEKGRKERESLQQMAEVTREGFRLKKILIEDWKKAREEKQKKLIELQAGKKSLEDQVEML 176 KE+ +E+E + + E +E R++ E KK REE++ + + +K E+ E Sbjct: 371 KEERMREQEKMWEQEEKMQEEERIR----EREKKMREEEETMREQEEKMQKQEENMWE-- 424 Query: 177 RTVKEEAEKPEREAKEQHQKLWEEQLAAAKAQQEQELAADAFKELDDDMDGTVSVTELQT 236 +EE E ++ EQ +KLWE++ K Q+++E + +++ D + ++ Sbjct: 425 ---QEEKEWQQQRLPEQKEKLWEQE----KMQEQEEKIWEQEEKIRDQEEMWGQEKKMWR 477 Query: 237 HPELDTDGDGALSEAEAQALLSGDTQTDATSFYDRVWAAIRDKYRSEALPTDLPAPSAPD 296 ++ D + E D + +R+W E + + Sbjct: 478 QEKMREQEDQMWEQEEKMR----DQEQKMWDQEERMWEQDERLREKEERMREQKKMWQQE 533 Query: 297 LTEPKEEQPPVPSSPTEEEEEEEEEEEEEAEEEEEEEDSEEAPPPLSPPQPASPAEEDKM 356 +E++ T ++EE+ EEE E E++ + EE + + +E+KM Sbjct: 534 EKMREEKKTQEQEKKTWDQEEKMREEERMREREKKMREEEEM---MREQEEKMQEQEEKM 590 Query: 357 PPYDEQTQAFIDAAQEARNKFEEAERSLKDMEESIRNLEQE 397 +E+ + QE K E E + + EE + EQE Sbjct: 591 REQEEKMWEQEEKMQEQEEKMWEQEEKMWEQEEEDKMQEQE 631 Score = 53.1 bits (126), Expect = 6e-07 Identities = 56/304 (18%), Positives = 128/304 (42%), Gaps = 22/304 (7%) Query: 113 ENTCKEKGRKERESLQQMAEVTREGFRLKKILIE----DWKKAREEKQKKLIELQAGKKS 168 E +E+ +K RE + M E + + ++ + E +W++ R +QK+ + Q + Sbjct: 391 EERIREREKKMREEEETMREQEEKMQKQEENMWEQEEKEWQQQRLPEQKEKLWEQEKMQE 450 Query: 169 LEDQVEMLRTVKEEAEKPEREAKEQHQKLWEEQLAAAKAQQ---EQELAADAFKELDDDM 225 E+++ +EE + + E Q +K+W ++ + Q ++E D +++ D Sbjct: 451 QEEKI----WEQEEKIRDQEEMWGQEKKMWRQEKMREQEDQMWEQEEKMRDQEQKMWDQE 506 Query: 226 DGTVSVTELQTHPELDTDGDGALSEAEAQALLSGDTQTDATSFYD-----RVWAAIRDKY 280 + E E + + E + TQ +D R +R++ Sbjct: 507 ERMWEQDERLREKEERMREQKKMWQQEEKMREEKKTQEQEKKTWDQEEKMREEERMRERE 566 Query: 281 RSEALPTDLPAPSAPDLTEPKEEQPPVPSSPTEEEEEEEEEEE------EEAEEEEEEED 334 + ++ + E +E+ E+EE+ +E+EE E+ E+EEE+ Sbjct: 567 KKMREEEEMMREQEEKMQEQEEKMREQEEKMWEQEEKMQEQEEKMWEQEEKMWEQEEEDK 626 Query: 335 SEEAPPPLSPPQPASPAEEDKMPPYDEQTQAFIDAAQEARNKFEEAERSLKDMEESIRNL 394 +E + + +E+KM +E+ + + +E K + E +++ EE ++ Sbjct: 627 MQEQEEMMWEQEEKMQEQEEKMWEQEEKMREQEEKMREQEEKMQGQEEKMREQEEKMQGQ 686 Query: 395 EQEI 398 E+++ Sbjct: 687 EEKM 690 Score = 50.1 bits (118), Expect = 5e-06 Identities = 65/304 (21%), Positives = 133/304 (43%), Gaps = 50/304 (16%) Query: 114 NTCKEKGRKERESLQQMAEVTREG----FRLKKILIEDWKKAREEKQKKLIE---LQAGK 166 NT +E+ ++ E L++ + R+ +R ++ L E K RE+++K + L+ + Sbjct: 230 NTLQEEMWRQEEELREQEKKIRKQEEKMWRQEERLREQEGKMREQEEKMRRQEKRLREQE 289 Query: 167 KSLEDQVEMLRTVKEEAEKPEREAKEQHQKLWEEQLAAAKAQQEQELAADAFKELDDDMD 226 K L +Q + LR K+ E+ E + +EQ +K+WE++ +QE+++ + + + Sbjct: 290 KELREQEKELREQKKLREQ-EEQMQEQEEKMWEQE--EKMREQEEKMWRQEERLWEQEKQ 346 Query: 227 GTVSVTELQTHPELDTDGDGALSEAEAQALLSGDTQTDATSFYDRVWAAIRDKYRSEALP 286 +++ E + D L E E + +++W +K + E Sbjct: 347 MREQEQKMRDQEERMWEQDERLREKE-----------ERMREQEKMWEQ-EEKMQEE--- 391 Query: 287 TDLPAPSAPDLTEPKEEQPPVPSSPTEEEEEEEEEEEEEAEEEEEEEDSEEAPPPLSPPQ 346 + +E++ E+EE+ +++EE E+EE+E ++ P Q Sbjct: 392 ---------ERIREREKKMREEEETMREQEEKMQKQEENMWEQEEKEWQQQR----LPEQ 438 Query: 347 PASPAEEDKMPPYD----EQTQAFIDA----AQEAR----NKFEEAERSLKDMEESIRNL 394 E++KM + EQ + D QE + K E E + + EE +R+ Sbjct: 439 KEKLWEQEKMQEQEEKIWEQEEKIRDQEEMWGQEKKMWRQEKMREQEDQMWEQEEKMRDQ 498 Query: 395 EQEI 398 EQ++ Sbjct: 499 EQKM 502 Score = 50.1 bits (118), Expect = 5e-06 Identities = 56/292 (19%), Positives = 122/292 (41%), Gaps = 16/292 (5%) Query: 113 ENTCKEKGRKERESLQQMAEVTREGFRLKKILIEDWKKAREEKQKKLIELQAGKKSLEDQ 172 E +E+ K E ++M E + +R ++ L E K+ RE++QK ++ ++ + +Q Sbjct: 309 EEQMQEQEEKMWEQEEKMREQEEKMWRQEERLWEQEKQMREQEQK----MRDQEERMWEQ 364 Query: 173 VEMLRTVKEEAEKPEREAKEQHQKLWEEQL---AAAKAQQEQELAADAFKELDDDMDGTV 229 E LR KEE + + + EQ +K+ EE+ K ++E+E + +++ + Sbjct: 365 DERLRE-KEERMREQEKMWEQEEKMQEEERIREREKKMREEEETMREQEEKMQKQEENMW 423 Query: 230 SVTELQTHPELDTDGDGALSEAEAQALLSGD--TQTDATSFYDRVWAAIRDKYRSEALPT 287 E + + + L E E Q + + +W + +R E + Sbjct: 424 EQEEKEWQQQRLPEQKEKLWEQEKMQEQEEKIWEQEEKIRDQEEMWGQEKKMWRQEKM-- 481 Query: 288 DLPAPSAPDLTEPKEEQPPVPSSPTEEEEEEEEEEEEEAEEEEEEEDSEEAPPPLSPPQP 347 + E +E+ ++EE E++E E+EE + ++ + Sbjct: 482 ---REQEDQMWEQEEKMRDQEQKMWDQEERMWEQDERLREKEERMREQKKMWQQEEKMRE 538 Query: 348 ASPAEEDKMPPYD-EQTQAFIDAAQEARNKFEEAERSLKDMEESIRNLEQEI 398 +E + +D E+ + +E K E E +++ EE ++ E+++ Sbjct: 539 EKKTQEQEKKTWDQEEKMREEERMREREKKMREEEEMMREQEEKMQEQEEKM 590 Score = 48.9 bits (115), Expect = 1e-05 Identities = 61/313 (19%), Positives = 123/313 (39%), Gaps = 51/313 (16%) Query: 117 KEKGRKERESLQQMAEVTREGFRLKKILIEDWKKAREEKQKKLIELQAGKKSLEDQVEM- 175 +EK +K+ E++ + E + RL + + W++ + ++Q++ I Q K + DQ EM Sbjct: 412 EEKMQKQEENMWEQEEKEWQQQRLPEQKEKLWEQEKMQEQEEKIWEQEEK--IRDQEEMW 469 Query: 176 -----------LRTVKEEAEKPEREAKEQHQKLW----------------EEQLAAAKAQ 208 +R +++ + E + ++Q QK+W EE++ K Sbjct: 470 GQEKKMWRQEKMREQEDQMWEQEEKMRDQEQKMWDQEERMWEQDERLREKEERMREQKKM 529 Query: 209 QEQELAADAFKELDDDMDGTVSVTELQTHPELDTDGDGALSEAEAQALLSGDTQTDATSF 268 +QE K+ + T E E + + + E E + + Sbjct: 530 WQQEEKMREEKKTQEQEKKTWDQEEKMREEERMREREKKMREEEEMMREQEEKMQEQ--- 586 Query: 269 YDRVWAAIRDKYRSEALPTDLPAPSAPDLTEPKEEQPPVPSSPTEEEEEEEEEE---EEE 325 +K R + + E EQ EE++ +E+EE E+E Sbjct: 587 --------EEKMREQEEKMWEQEEKMQEQEEKMWEQEEKMWEQEEEDKMQEQEEMMWEQE 638 Query: 326 AEEEEEEEDSEEAPPPLSPPQPASPAEEDKMPPYDEQTQAFIDAAQEARNKFEEAERSLK 385 + +E+EE E + +E+KM +E+ Q + +E K + E ++ Sbjct: 639 EKMQEQEEKMWEQEEKMR-------EQEEKMREQEEKMQGQEEKMREQEEKMQGQEEKMR 691 Query: 386 DMEESIRNLEQEI 398 + EE +R E+++ Sbjct: 692 EQEEKMRGQEEKM 704 Score = 47.8 bits (112), Expect = 3e-05 Identities = 63/289 (21%), Positives = 122/289 (42%), Gaps = 44/289 (15%) Query: 124 RESLQQMAEVTREGFRLKKILIEDWKKAREEKQKKLIELQAGKKSLEDQVEMLRTVKEEA 183 RE +M E + R +K L E K+ RE+ +K+L E +K L +Q E ++ +E+ Sbjct: 265 REQEGKMREQEEKMRRQEKRLREQEKELREQ-EKELRE----QKKLREQEEQMQEQEEKM 319 Query: 184 EKPEREAKEQHQKLW--EEQLAAAKAQ---QEQELAADAFKELDDD-----MDGTVSVTE 233 + E + +EQ +K+W EE+L + Q QEQ++ + + D + + E Sbjct: 320 WEQEEKMREQEEKMWRQEERLWEQEKQMREQEQKMRDQEERMWEQDERLREKEERMREQE 379 Query: 234 LQTHPELDTDGDGALSEAEAQALLSGDTQTDATSFY----DRVWAAIRDKYRSEALPTDL 289 E + + E E + +T + + +W +++ + LP Sbjct: 380 KMWEQEEKMQEEERIREREKKMREEEETMREQEEKMQKQEENMWEQEEKEWQQQRLP--- 436 Query: 290 PAPSAPDLTEPKEEQPPVPSSPTEEEEEEEEEEEEEAEEEEEEEDSEEAPPPLSPPQPAS 349 E KE+ E+E+ +E+EE+ E+EE+ D EE Q Sbjct: 437 ---------EQKEK--------LWEQEKMQEQEEKIWEQEEKIRDQEE-----MWGQEKK 474 Query: 350 PAEEDKMPPYDEQTQAFIDAAQEARNKFEEAERSLKDMEESIRNLEQEI 398 ++KM ++Q + ++ K + E + + +E +R E+ + Sbjct: 475 MWRQEKMREQEDQMWEQEEKMRDQEQKMWDQEERMWEQDERLREKEERM 523 Score = 30.8 bits (68), Expect = 3.2 Identities = 21/92 (22%), Positives = 40/92 (43%), Gaps = 16/92 (17%) Query: 307 VPSSPTEEEEEEEEEEEEEAEEEEEEEDSEEAPPPLSPPQPASPAEEDKMPPYDEQTQAF 366 +P T +EE +EEE E+E++ +E+KM +E+ + Sbjct: 224 LPQVQTNTLQEEMWRQEEELREQEKK----------------IRKQEEKMWRQEERLREQ 267 Query: 367 IDAAQEARNKFEEAERSLKDMEESIRNLEQEI 398 +E K E+ L++ E+ +R E+E+ Sbjct: 268 EGKMREQEEKMRRQEKRLREQEKELREQEKEL 299 >gi|17975763 myelin transcription factor 1 [Homo sapiens] Length = 1121 Score = 57.4 bits (137), Expect = 3e-08 Identities = 30/59 (50%), Positives = 35/59 (59%) Query: 299 EPKEEQPPVPSSPTEEEEEEEEEEEEEAEEEEEEEDSEEAPPPLSPPQPASPAEEDKMP 357 E +EE+ EEEEEEEEEEEEE EEEEEEE+ EEA P + + S K P Sbjct: 268 EEEEEEDEEEEEEEEEEEEEEEEEEEEEEEEEEEEEEEEAAPDVIFQEDTSHTSAQKAP 326 Score = 53.1 bits (126), Expect = 6e-07 Identities = 27/49 (55%), Positives = 31/49 (63%) Query: 296 DLTEPKEEQPPVPSSPTEEEEEEEEEEEEEAEEEEEEEDSEEAPPPLSP 344 D E +EE+ EEEEEEEEEEEEE EEEEEEE+ EE +P Sbjct: 261 DEEEEEEEEEEEEDEEEEEEEEEEEEEEEEEEEEEEEEEEEEEEEEAAP 309 Score = 50.4 bits (119), Expect = 4e-06 Identities = 25/52 (48%), Positives = 32/52 (61%) Query: 299 EPKEEQPPVPSSPTEEEEEEEEEEEEEAEEEEEEEDSEEAPPPLSPPQPASP 350 E ++E+ EE+EEEEEEEEEE EEEEEEE+ EE + A+P Sbjct: 258 EEEDEEEEEEEEEEEEDEEEEEEEEEEEEEEEEEEEEEEEEEEEEEEEEAAP 309 Score = 50.4 bits (119), Expect = 4e-06 Identities = 27/56 (48%), Positives = 32/56 (57%) Query: 299 EPKEEQPPVPSSPTEEEEEEEEEEEEEAEEEEEEEDSEEAPPPLSPPQPASPAEED 354 + +EE+ EEEEEEEEEEEEE EEEEEEE+ EE P +ED Sbjct: 261 DEEEEEEEEEEEEDEEEEEEEEEEEEEEEEEEEEEEEEEEEEEEEEAAPDVIFQED 316 Score = 50.4 bits (119), Expect = 4e-06 Identities = 28/61 (45%), Positives = 34/61 (55%) Query: 313 EEEEEEEEEEEEEAEEEEEEEDSEEAPPPLSPPQPASPAEEDKMPPYDEQTQAFIDAAQE 372 EEEEEEEEE+EEE EEEEEEE+ EE + EE+ P Q +AQ+ Sbjct: 265 EEEEEEEEEDEEEEEEEEEEEEEEEEEEEEEEEEEEEEEEEEAAPDVIFQEDTSHTSAQK 324 Query: 373 A 373 A Sbjct: 325 A 325 Score = 50.1 bits (118), Expect = 5e-06 Identities = 29/86 (33%), Positives = 45/86 (52%), Gaps = 5/86 (5%) Query: 298 TEPKEEQPPVPSSPTEEEEEEEEEEEEEAEEEEEEEDSEEAPPPLSPPQPASPAEEDKMP 357 +E +Q + S E+EEEEEEEEEEE +EEEEEE+ EE + EE++ Sbjct: 245 SEESSKQKGILSHEEEDEEEEEEEEEEEEDEEEEEEEEEE-----EEEEEEEEEEEEEEE 299 Query: 358 PYDEQTQAFIDAAQEARNKFEEAERS 383 +E+ +A D + A+++ Sbjct: 300 EEEEEEEAAPDVIFQEDTSHTSAQKA 325 Score = 43.1 bits (100), Expect = 6e-04 Identities = 25/60 (41%), Positives = 31/60 (51%), Gaps = 5/60 (8%) Query: 299 EPKEEQPPVPSSPTEEEEEEEEEEEEEAE-----EEEEEEDSEEAPPPLSPPQPASPAEE 353 E +EE+ EEEEEEEEEEEEEA +E+ S + P L P+ SP E Sbjct: 280 EEEEEEEEEEEEEEEEEEEEEEEEEEEAAPDVIFQEDTSHTSAQKAPELRGPESPSPKPE 339 Score = 40.4 bits (93), Expect = 0.004 Identities = 36/133 (27%), Positives = 61/133 (45%), Gaps = 12/133 (9%) Query: 113 ENTCKEKGRK----ERESLQQMAEVTREGFR-LKKILIEDWKKAREEKQKKLIELQAGKK 167 E E+G K + E +++ EVT E + L +ED KQK ++ + + Sbjct: 203 EGAASEEGEKGLFIQPEDAEEVVEVTTERSQDLCPQSLEDAASEESSKQKGILSHEEEDE 262 Query: 168 SLEDQVEMLRTVKEEAEKPEREAKEQHQKLWEEQLAAAKAQQEQELAADAFKELDDDMDG 227 E++ E +EE E+ E E +E+ ++ EE+ + ++E+E A D + D Sbjct: 263 EEEEEEEEEEEDEEEEEEEEEEEEEEEEE-EEEEEEEEEEEEEEEAAPDVIFQED----- 316 Query: 228 TVSVTELQTHPEL 240 S T Q PEL Sbjct: 317 -TSHTSAQKAPEL 328 Score = 30.8 bits (68), Expect = 3.2 Identities = 21/90 (23%), Positives = 39/90 (43%), Gaps = 7/90 (7%) Query: 298 TEPKEEQPPVPSSPTEEEEEEEEEEEEEAEEEEEEEDSEEAPPPLSPPQPASPAEEDKMP 357 TE ++ P EE +++ EEE+EEE+ EE + EE++ Sbjct: 229 TERSQDLCPQSLEDAASEESSKQKGILSHEEEDEEEEEEE-------EEEEEDEEEEEEE 281 Query: 358 PYDEQTQAFIDAAQEARNKFEEAERSLKDM 387 +E+ + + +E + EE E + D+ Sbjct: 282 EEEEEEEEEEEEEEEEEEEEEEEEEAAPDV 311 >gi|100816397 MYST histone acetyltransferase (monocytic leukemia) 4 [Homo sapiens] Length = 2073 Score = 57.4 bits (137), Expect = 3e-08 Identities = 27/49 (55%), Positives = 35/49 (71%) Query: 298 TEPKEEQPPVPSSPTEEEEEEEEEEEEEAEEEEEEEDSEEAPPPLSPPQ 346 +E +EE+ EEEEEE+EEEEEE EEEEEEE+ + +PP L+ PQ Sbjct: 1069 SEEEEEEEDEEEEEEEEEEEEDEEEEEEEEEEEEEENIQSSPPRLTKPQ 1117 Score = 52.8 bits (125), Expect = 8e-07 Identities = 40/111 (36%), Positives = 57/111 (51%), Gaps = 6/111 (5%) Query: 250 EAEAQALLSGDTQTDATSFYDRVWAAIRDKYRSEALPTDLPAPSAPDLTEPKEEQPPVPS 309 E E Q +LS T+ ++ +V + + + E+ P +L++ E+ Sbjct: 1019 EKEEQEILS--TRANSRQSPAKVQSKNKYLHSPESRPVTGERGQLLELSKESSEEEE-EE 1075 Query: 310 SPTEEEEEEEEEEEEEAEEEEEEEDSEEAPPPLSPP---QPASPAEEDKMP 357 EEEEEEEEEEE+E EEEEEEE+ EE SPP +P S A + K P Sbjct: 1076 EDEEEEEEEEEEEEDEEEEEEEEEEEEEENIQSSPPRLTKPQSVAIKRKRP 1126 Score = 50.1 bits (118), Expect = 5e-06 Identities = 47/153 (30%), Positives = 65/153 (42%), Gaps = 15/153 (9%) Query: 234 LQTHPELDTDGDGALSEAEAQALLSGDTQTDATSFYDRVWAAIRDKYRSEAL-------P 286 L T PE + D ++ E + G T + V K EAL Sbjct: 1273 LYTPPETPMEPDEQVTVEEQKETSEGKTSPSPIRIEEEV------KETGEALLPQEENRR 1326 Query: 287 TDLPAPSAPDLTEPKEEQPPVPSSPTEEEEEEEEEEEEEAEEEEEEEDSEEAPPPLSPPQ 346 + AP +P+ T P E+ P EEEEEEEEEEEEE EEEE EE+ P Sbjct: 1327 EETCAPVSPN-TSPGEKPEDDLIKP-EEEEEEEEEEEEEEEEEEGEEEEGGGNVEKDPDG 1384 Query: 347 PASPAEEDKMPPYDEQTQAFIDAAQEARNKFEE 379 S +E+ +++ A +D +E + EE Sbjct: 1385 AKSQEKEEPEISTEKEDSARLDDHEEEEEEDEE 1417 Score = 41.6 bits (96), Expect = 0.002 Identities = 36/117 (30%), Positives = 51/117 (43%), Gaps = 12/117 (10%) Query: 285 LPTDLPAPSAPDLTEPKEEQPPVP---SSPTEEEEEEEEEEEEEAEEEEEEEDSEEAPPP 341 L T P PD EEQ +SP+ EEE +E EA +EE EE P Sbjct: 1273 LYTPPETPMEPDEQVTVEEQKETSEGKTSPSPIRIEEEVKETGEALLPQEENRREETCAP 1332 Query: 342 LSP-PQPASPAEEDKMPPYDEQTQAFIDAAQEARNKFEEAERSLKDMEESIRNLEQE 397 +SP P E+D + P +E+ +E + EE E + EE N+E++ Sbjct: 1333 VSPNTSPGEKPEDDLIKPEEEE--------EEEEEEEEEEEEEEGEEEEGGGNVEKD 1381 Score = 41.6 bits (96), Expect = 0.002 Identities = 37/120 (30%), Positives = 50/120 (41%), Gaps = 21/120 (17%) Query: 296 DLTEPKEEQPPVPSSPTEEEEEEEEEEEEEAE---------------EEEEEEDSEEAPP 340 DL +P+EE+ EEEEEEEEEE EE E E+EE E S E Sbjct: 1346 DLIKPEEEE----EEEEEEEEEEEEEEGEEEEGGGNVEKDPDGAKSQEKEEPEISTEKED 1401 Query: 341 PLSPPQPASPAEEDKMPPYDEQTQAFIDAAQEARNKFEEAERSLKDMEESIRNLEQEISF 400 EED+ P ++E A D ++ + E E+ E LE + +F Sbjct: 1402 SARLDDHEEEEEEDEEPSHNEDHDA--DDEDDSHMESAEVEKEELPRESFKEVLENQETF 1459 Score = 36.6 bits (83), Expect = 0.058 Identities = 32/123 (26%), Positives = 51/123 (41%), Gaps = 10/123 (8%) Query: 245 DGALSEAEAQALLSGDTQTDATSFYDRVWAAIRDKYRSEALPTDLPAPSAPDLTEPKEEQ 304 + A+SE E +A + + S ++ K E L T + +P + K + Sbjct: 994 NAAVSEEEREAEKEAERLMEQASCWE--------KEEQEILSTRANSRQSPAKVQSKNKY 1045 Query: 305 PPVPSSP--TEEEEEEEEEEEEEAEEEEEEEDSEEAPPPLSPPQPASPAEEDKMPPYDEQ 362 P S T E + E +E +EEEEEEED EE + EE++ +E Sbjct: 1046 LHSPESRPVTGERGQLLELSKESSEEEEEEEDEEEEEEEEEEEEDEEEEEEEEEEEEEEN 1105 Query: 363 TQA 365 Q+ Sbjct: 1106 IQS 1108 Score = 35.0 bits (79), Expect = 0.17 Identities = 48/254 (18%), Positives = 99/254 (38%), Gaps = 25/254 (9%) Query: 165 GKKSLEDQVEMLRTVKEEAEKPEREAKEQHQKLWEEQLAAAKAQQEQELAADAFKELDDD 224 G+K +D ++ +EE E+ E E +E+ ++ EE+ +++ + A KE + Sbjct: 1340 GEKPEDDLIKP----EEEEEEEEEEEEEEEEEEGEEEEGGGNVEKDPDGAKSQEKEEPEI 1395 Query: 225 MDGTVSVTELQTHPELDTDGDGALSEAEAQALLSGDTQTDATSF--YDRVWAAIRDKYRS 282 L H E + + + + A D+ ++ + + ++ + Sbjct: 1396 STEKEDSARLDDHEEEEEEDEEPSHNEDHDADDEDDSHMESAEVEKEELPRESFKEVLEN 1455 Query: 283 EALPTDL---PAPSAP--------DLTEPKEEQP-PVPSSPTEEEEEEEEEEEEEAEEEE 330 + DL P S P DLT +P + P E +EE E +++ Sbjct: 1456 QETFLDLNVQPGHSNPEVLMDCGVDLTASCNSEPKELAGDPEAVPESDEEPPPGEQAQKQ 1515 Query: 331 EEEDSEEAPPPLSPPQPASPAEEDKMPPYDEQTQAFIDAAQEARNKFEEAERSLKDMEES 390 ++++S+E PA+ M E QA QE+ + ++ + + +E+ Sbjct: 1516 DQKNSKEVDTEFKEGNPAT------MEIDSETVQAVQSLTQESSEQ-DDTFQDCAETQEA 1568 Query: 391 IRNLEQEISFDFGP 404 R+L+ D P Sbjct: 1569 CRSLQNYTRADQSP 1582 >gi|117414137 retinitis pigmentosa 1-like 1 [Homo sapiens] Length = 2400 Score = 57.4 bits (137), Expect = 3e-08 Identities = 55/241 (22%), Positives = 104/241 (43%), Gaps = 12/241 (4%) Query: 150 KAREEKQKKLIELQAGKKSLEDQVEMLRTVKEEAEKPEREAKEQHQKLWEEQLAAAKAQQ 209 + + + + ++IE Q ++ + + E + ++ E E E E + Q + E + A +A+ Sbjct: 1951 EGQTQPESEVIESQEAEEEAQPESEDVEALEVEVETQEAEGEAQPES---EDVEAPEAEG 2007 Query: 210 EQELAADAFKELDDDMDGTVSVTELQTHPELDTDGDGALSEAEAQALLSGDTQTDATSFY 269 E + +A +E + DG + + + + +G+ +E +AQ G +A Sbjct: 2008 EMQ---EAEEEAQPESDGVEAQPKSEGEEAQEVEGETQKTEGDAQPESDGVEAPEAEEEA 2064 Query: 270 DRVWAAIRDKYRSEALPT--DLPAPSAPDLTEPKEEQPPVPSSPTEEEEEEEEEEEEEAE 327 +++ EA P D+ A A +P+ E P + E ++ E E E Sbjct: 2065 QEAEGEVQEA-EGEAHPESEDVDAQEAEGEAQPESEGVEAPEAEGEAQKAEGIEAPETEG 2123 Query: 328 EEEEEEDSEEAPPPLSPPQPASPAEEDKMPPYDEQTQAFIDAAQEARNKFEEAERSLKDM 387 E + E + EAP QP S E + + Q ++ AQEA EEA+ L+ + Sbjct: 2124 EAQPESEGIEAPEAEGEAQPESEGVEAQDAEGEAQPESEGIEAQEAE---EEAQPELEGV 2180 Query: 388 E 388 E Sbjct: 2181 E 2181 Score = 52.0 bits (123), Expect = 1e-06 Identities = 52/212 (24%), Positives = 83/212 (39%), Gaps = 12/212 (5%) Query: 181 EEAEKPEREAKEQHQKLWEEQLAAAKAQQEQELAADAFKELDDDMDGTVSVTELQTHPEL 240 E+ E PE E + Q + E A Q + A+A + + T SV L+T E Sbjct: 1872 EDVEAPEAEGEAQPESEDVETPEAEWEVQPESEGAEAPEAEKEAQPETESVEALETEGED 1931 Query: 241 DTDGDGALSEAEAQALLSGDTQTDATSFYDRVWAAIRDKYRS----EALPTDLPAPSAPD 296 + + +GA ++ +A + QT S A + EAL ++ A Sbjct: 1932 EPESEGAEAQEAEEAAQEAEGQTQPESEVIESQEAEEEAQPESEDVEALEVEVETQEAEG 1991 Query: 297 LTEPKEEQPPVPSSPTEEEEEEEEEEEEEAEEEEEEEDSEEAPPPLSPPQPASPAEEDKM 356 +P+ E P E E E +E EE + E D EA P + E + Sbjct: 1992 EAQPESEDVEAP--------EAEGEMQEAEEEAQPESDGVEAQPKSEGEEAQEVEGETQK 2043 Query: 357 PPYDEQTQAFIDAAQEARNKFEEAERSLKDME 388 D Q ++ A EA + +EAE +++ E Sbjct: 2044 TEGDAQPESDGVEAPEAEEEAQEAEGEVQEAE 2075 Score = 43.5 bits (101), Expect = 5e-04 Identities = 32/116 (27%), Positives = 47/116 (40%), Gaps = 9/116 (7%) Query: 292 PSAPDLTEPKEEQPPVPSSPTEEEEEEEEEEEEEAEEEEEEEDSEEAPPPLSPPQPASPA 351 P + D+ P+ E P S E E E E + E+E E E +EA P + Sbjct: 1869 PESEDVEAPEAEGEAQPESEDVETPEAEWEVQPESEGAEAPEAEKEAQPETESVEALETE 1928 Query: 352 EEDKMPPYDEQTQAFIDAAQEARN---------KFEEAERSLKDMEESIRNLEQEI 398 ED+ + Q +AAQEA + +EAE + E + LE E+ Sbjct: 1929 GEDEPESEGAEAQEAEEAAQEAEGQTQPESEVIESQEAEEEAQPESEDVEALEVEV 1984 Score = 43.1 bits (100), Expect = 6e-04 Identities = 63/282 (22%), Positives = 104/282 (36%), Gaps = 12/282 (4%) Query: 146 EDWKKAREEKQKKLIELQAGKKSLE--DQVEMLRTVKEEAEKPEREAKEQHQKLWEEQLA 203 E+ ++ E QK + Q +E + E + + E ++ E EA + + + + Q A Sbjct: 2032 EEAQEVEGETQKTEGDAQPESDGVEAPEAEEEAQEAEGEVQEAEGEAHPESEDV-DAQEA 2090 Query: 204 AAKAQQEQELAADAFKELDDDMDGTVSVTELQTHPELDTDG-DGALSEAEAQALLSGDTQ 262 +AQ E E E + + E + + +++G + +E EAQ G Sbjct: 2091 EGEAQPESEGVEAPEAEGEAQKAEGIEAPETEGEAQPESEGIEAPEAEGEAQPESEGVEA 2150 Query: 263 TDATSFYDRVWAAIRDKYRSEALPTDLPAPSAPDL---TEPKEEQPPVPSSPTEEEEEEE 319 DA I + E +L AP+ +P+ E P + E + E E Sbjct: 2151 QDAEGEAQPESEGIEAQEAEEEAQPELEGVEAPEAEGEAQPESEGIEAPEAEGEAQPELE 2210 Query: 320 EEEEEEAEEE-EEEEDSEEAPPPLSPPQPASPAE---EDKMPPYDEQTQAFIDAAQEARN 375 E EAEEE + E + E P QP S E E K P + A E+ + Sbjct: 2211 GVEAPEAEEEAQPEPEGVETPEAEGEAQPESEGETQGEKKGSPQVSLGDGQSEEASESSS 2270 Query: 376 KFEEAERSLKDMEESIRNLEQEISFDFGPNGEFAYLYSQCYE 417 E +R Q GP+ A + C++ Sbjct: 2271 PVPE-DRPTPPPSPGGDTPHQRPGSQTGPSSSRASSWGNCWQ 2311 Score = 39.3 bits (90), Expect = 0.009 Identities = 58/268 (21%), Positives = 99/268 (36%), Gaps = 24/268 (8%) Query: 146 EDWKKAREEKQKKLIELQAGKKSLEDQVEMLRTVKEEAEKPEREAKEQHQKLWEE-QLAA 204 E ++ +K KL E + G +++ + A EA+++ + + E + Sbjct: 1747 EGSQRLNRDKDPKLGEAE-GDAMAQEREGKTHNSETSAGSELGEAEQEGEGISERGETGG 1805 Query: 205 AKAQQEQELAADAFKELDDD---MDGTVSVTELQTHPELDTDGDGALS-EAEAQAL-LSG 259 + E L +A D D DG + + E + +G + EAE A G Sbjct: 1806 QGSGHEDNLQGEAAAGGDQDPGQSDGAEGIEAPEAEGEAQPESEGVEAPEAEGDAQEAEG 1865 Query: 260 DTQTDATSFYDRVWAAIRDKYRSEALPT--DLPAPSAPDLTEPKEEQPPVPSSPTEEEEE 317 + Q ++ + EA P D+ P A +P+ E P + E + E Sbjct: 1866 EAQPESEDVE-------APEAEGEAQPESEDVETPEAEWEVQPESEGAEAPEAEKEAQPE 1918 Query: 318 EEE--------EEEEEAEEEEEEEDSEEAPPPLSPPQPASPAEEDKMPPYDEQTQAFIDA 369 E E+E E+E E +E E A QP S E + + Q ++ Sbjct: 1919 TESVEALETEGEDEPESEGAEAQEAEEAAQEAEGQTQPESEVIESQEAEEEAQPESEDVE 1978 Query: 370 AQEARNKFEEAERSLKDMEESIRNLEQE 397 A E + +EAE + E + E E Sbjct: 1979 ALEVEVETQEAEGEAQPESEDVEAPEAE 2006 Score = 36.2 bits (82), Expect = 0.076 Identities = 43/205 (20%), Positives = 76/205 (37%), Gaps = 22/205 (10%) Query: 153 EEKQKKLIELQAGKKSLEDQVEMLRTVKEEAEKPEREAKEQHQKLWEEQLAAAKAQQEQE 212 E ++ ++L+ K+ E + V+ E K E +E+ +L E + + QQE+E Sbjct: 1294 ENTVQEEVQLEETKEGTEGEGLQEEAVQLEETKTEEGLQEEGVQLEETKETEGEGQQEEE 1353 Query: 213 LAADAFKELDDD--MDGTVSVTELQTHPELDTDGDGALSEAEAQALLSGDTQTDATSFYD 270 + +E + + V + E++ PE G+ AL E + L + Sbjct: 1354 AQLEEIEETGGEGLQEEGVQLEEVKEGPEGGLQGE-ALEEGLKEEGLPEE---------- 1402 Query: 271 RVWAAIRDKYRSEALPTDLPAPSAPDLTEPKE------EQPPVPSSPTEEEEEEEEEEEE 324 ++ + SEA D D + +E P P+ TEE E E Sbjct: 1403 ---GSVHGQELSEASSPDGKGSQEDDPVQEEEAGRASASAEPCPAEGTEEPTEPPSHLSE 1459 Query: 325 EAEEEEEEEDSEEAPPPLSPPQPAS 349 E + + P L P A+ Sbjct: 1460 TDPSASERQSGSQLEPGLEKPPGAT 1484 Score = 35.4 bits (80), Expect = 0.13 Identities = 44/205 (21%), Positives = 76/205 (37%), Gaps = 21/205 (10%) Query: 153 EEKQKKLIELQAGKKSLEDQVEMLRTVKEEAEKPEREAKEQHQKLWEEQLAAAKAQQEQE 212 E++ ++ E Q +LE E TV+EE + E + + + L EE + + + E+ Sbjct: 1273 EDEAERDSEEQRASSNLEQLAE--NTVQEEVQLEETKEGTEGEGLQEEAVQLEETKTEEG 1330 Query: 213 LAADAFK-ELDDDMDGTVSVTELQTHPELDTDGDGALSEAEAQALLSGDTQTDATSFYDR 271 L + + E + +G E E++ G L E Q + Sbjct: 1331 LQEEGVQLEETKETEGEGQQEEEAQLEEIEETGGEGLQEEGVQL--------------EE 1376 Query: 272 VWAAIRDKYRSEALPTDLPAPSAPDLTEPKEEQPPVPSSP----TEEEEEEEEEEEEEAE 327 V + EAL L P+ ++ SSP ++E++ +EEE A Sbjct: 1377 VKEGPEGGLQGEALEEGLKEEGLPEEGSVHGQELSEASSPDGKGSQEDDPVQEEEAGRAS 1436 Query: 328 EEEEEEDSEEAPPPLSPPQPASPAE 352 E +E P PP S + Sbjct: 1437 ASAEPCPAEGTEEPTEPPSHLSETD 1461 >gi|14249738 N-acetylglucosamine-1-phosphotransferase, gamma subunit [Homo sapiens] Length = 305 Score = 56.6 bits (135), Expect = 5e-08 Identities = 32/105 (30%), Positives = 46/105 (43%), Gaps = 5/105 (4%) Query: 411 LYSQCYELTTNEYVYRLCPFKLVSQKPKL---GGSPTSLGTWGSWIGPDHDKFSAMKYEQ 467 L +C+ L + Y Y CPF V+Q + LG W W ++ F+ M Sbjct: 67 LSGKCFSLVESTYKYEFCPFHNVTQHEQTFRWNAYSGILGIWHEW-EIANNTFTGMWMRD 125 Query: 468 GTGCWQGPNRSTTVRLLCGKETMVTSTTEPSRCEYLMELMTPAAC 512 G C + +R + V L CGK + +EPS C Y + TP C Sbjct: 126 GDAC-RSRSRQSKVELACGKSNRLAHVSEPSTCVYALTFETPLVC 169 >gi|154759293 cysteine-rich hydrophobic domain 1 [Homo sapiens] Length = 224 Score = 56.6 bits (135), Expect = 5e-08 Identities = 32/68 (47%), Positives = 39/68 (57%), Gaps = 11/68 (16%) Query: 285 LPTDLPAPSAPDLTEPKEEQPPVPSSPT-----------EEEEEEEEEEEEEAEEEEEEE 333 LP + +L E +EE+ SS +EE+EEEEEEEEE EEEEEEE Sbjct: 5 LPNMAEFDTISELEEEEEEEAATSSSSPSSSSSVSGPDDDEEDEEEEEEEEEEEEEEEEE 64 Query: 334 DSEEAPPP 341 + EEAPPP Sbjct: 65 EEEEAPPP 72 Score = 29.3 bits (64), Expect = 9.3 Identities = 17/57 (29%), Positives = 29/57 (50%), Gaps = 4/57 (7%) Query: 325 EAEEEEEEEDSEEAPPPLSPPQPASPAEEDKMPPYDEQTQAFIDAAQEARNKFEEAE 381 E EEEEEEE + + P S + P ++++ DE+ + + +E + EE E Sbjct: 16 ELEEEEEEEAATSSSSPSSSSSVSGPDDDEE----DEEEEEEEEEEEEEEEEEEEEE 68 >gi|239745079 PREDICTED: Putative golgin subfamily A member 6-like protein 6 [Homo sapiens] Length = 724 Score = 55.5 bits (132), Expect = 1e-07 Identities = 54/294 (18%), Positives = 133/294 (45%), Gaps = 15/294 (5%) Query: 117 KEKGRKERESLQQMAEVTREGFRLKKILIEDWKKAREEKQ---KKLIELQAGKKSLEDQV 173 +EK R++ E +++ E R R ++++ E +K R +++ +K +++ ++ + ++ Sbjct: 381 EEKIREQEEKIREQEEKMR---RQEEMMWEKEEKMRRQEEMMWEKEEKMRRQEEMMWEKE 437 Query: 174 EMLRTVKEEAEKPEREAKEQHQKLWEEQLAAAKAQQEQELAADAFKELDDDMDGTVSVTE 233 E +R ++E+ + E+ +++ ++ EE++ + +QEQE +E + + + E Sbjct: 438 EKIRELEEKMHEQEKIREQEEKRQEEEKIREQEKRQEQEAKMWRQEEKIREQEEKIREQE 497 Query: 234 --LQTHPELDTDGDGALSEAEAQALLSGDTQTDATSFYDRVWA------AIRDKYRSEAL 285 + E + + E + Q Q + + +W +K R + Sbjct: 498 EKMWRQEEKIHEQEKIREEEKRQEQEEMWRQEEKIREQEEIWRQKEKIHEQEEKIRKQEE 557 Query: 286 PTDLPAPSAPDLTEP-KEEQPPVPSSPTEEEEEEEEEEEEEAEEEEEEEDSEEAPPPLSP 344 D E +E++ V + E+EE+ E+E + E+EE ++E + Sbjct: 558 KMWRQEEKMHDQEEKIREQEEKVWRQEEKIREQEEKIREQEEKIREQEEMTQEQEEKMGE 617 Query: 345 PQPASPAEEDKMPPYDEQTQAFIDAAQEARNKFEEAERSLKDMEESIRNLEQEI 398 + +E+KM +E+ + + +E K E E +++ EE ++ E+++ Sbjct: 618 QEEKMCEQEEKMQEQEEKMRRQEEKIREQEKKIREQEEKIREQEEMMQEQEEKM 671 Score = 55.1 bits (131), Expect = 2e-07 Identities = 50/279 (17%), Positives = 113/279 (40%), Gaps = 23/279 (8%) Query: 122 KERESLQQMAEVTREGFRLKKILIEDWKKAREEKQKKLIELQAGKKSLEDQVEMLRTVKE 181 +E E ++ + E ++ I++W++ +E+++K+ E + + + +Q E +R +E Sbjct: 347 EENELWNRLNQQQEEKMWRQEEKIQEWEEKIQEQEEKIREQE---EKIREQEEKMRRQEE 403 Query: 182 EAEKPEREAKEQHQKLWEEQLAAAKAQQEQELAADAFKELDDDMDGTVSVTELQTHPELD 241 + E + + Q + +WE++ + ++ + +EL++ M + E + + + Sbjct: 404 MMWEKEEKMRRQEEMMWEKEEKMRRQEEMMWEKEEKIRELEEKMHEQEKIREQEEKRQEE 463 Query: 242 TDGDGALSEAEAQALLSGDTQTDATSFYDRVWAAIRDKYRSEALPTDLPAPSAPDLTEPK 301 E +A ++W +K R + E Sbjct: 464 EKIREQEKRQEQEA---------------KMWRQ-EEKIREQEEKIREQEEKMWRQEEKI 507 Query: 302 EEQPPVPSSPTEEEEEEEEEEEEEAEEEEE----EEDSEEAPPPLSPPQPASPAEEDKMP 357 EQ + +E+EE +EE+ E+EE +E E + + +E+KM Sbjct: 508 HEQEKIREEEKRQEQEEMWRQEEKIREQEEIWRQKEKIHEQEEKIRKQEEKMWRQEEKMH 567 Query: 358 PYDEQTQAFIDAAQEARNKFEEAERSLKDMEESIRNLEQ 396 +E+ + + K E E +++ EE IR E+ Sbjct: 568 DQEEKIREQEEKVWRQEEKIREQEEKIREQEEKIREQEE 606 Score = 51.6 bits (122), Expect = 2e-06 Identities = 58/305 (19%), Positives = 132/305 (43%), Gaps = 30/305 (9%) Query: 117 KEKGRKERESLQQMAEVTREGFRLKKILIEDWK-KAREEKQKKLIELQAGKKSLEDQVEM 175 +EK R++ E + + E RE L++ + E K + +EEK+++ +++ +K E + +M Sbjct: 423 EEKMRRQEEMMWEKEEKIRE---LEEKMHEQEKIREQEEKRQEEEKIREQEKRQEQEAKM 479 Query: 176 LRTVKEEAEKPEREAKEQHQKLWEEQLAAAKAQQEQELAADAFKELDDDM----DGTVSV 231 R +E+ + E + +EQ +K+W ++ K +++++ + ++ ++M + Sbjct: 480 WRQ-EEKIREQEEKIREQEEKMWRQE---EKIHEQEKIREEEKRQEQEEMWRQEEKIREQ 535 Query: 232 TELQTHPELDTDGDGALSEAEA----QALLSGDTQTDATSFYDRVWAA----------IR 277 E+ E + + + + E Q D + ++VW IR Sbjct: 536 EEIWRQKEKIHEQEEKIRKQEEKMWRQEEKMHDQEEKIREQEEKVWRQEEKIREQEEKIR 595 Query: 278 DKYRSEALPTDLPAPSAPDLTEPKEEQPPVPSSPTEEEE----EEEEEEEEEAEEEEEEE 333 ++ ++ + E +E+ E+EE +EE+ E+E + E+EE Sbjct: 596 EQEEKIREQEEMTQEQEEKMGEQEEKMCEQEEKMQEQEEKMRRQEEKIREQEKKIREQEE 655 Query: 334 DSEEAPPPLSPPQPASPAEEDKMPPYDEQTQAFIDAAQEARNKFEEAERSLKDMEESIRN 393 E + + +E+KM +E+ Q + + K E E L+ EE ++ Sbjct: 656 KIREQEEMMQEQEEKMWEQEEKMCEQEEKMQEQEEKMRRQEEKMWEQEVRLRQQEEKMQE 715 Query: 394 LEQEI 398 ++ + Sbjct: 716 HQEHL 720 Score = 45.1 bits (105), Expect = 2e-04 Identities = 50/260 (19%), Positives = 115/260 (44%), Gaps = 27/260 (10%) Query: 117 KEKGRKERESLQQMAEVTREGFRLKKILIEDWKKAREEKQKKLIELQAGKKSLEDQVEML 176 +EK R++ E +++ E + +R ++ + E K EEK+++ E+ ++ + +Q E+ Sbjct: 483 EEKIREQEEKIREQEE---KMWRQEEKIHEQEKIREEEKRQEQEEMWRQEEKIREQEEIW 539 Query: 177 RTVKEEAEKPEREAKEQHQKLW--EEQLAAAKA---QQEQELAADAFKELDDDMDGTVSV 231 R KE+ + E + ++Q +K+W EE++ + +QE+++ K + + Sbjct: 540 RQ-KEKIHEQEEKIRKQEEKMWRQEEKMHDQEEKIREQEEKVWRQEEKIREQEEKIREQE 598 Query: 232 TELQTHPELDTDGDGALSEAEAQALLSGDTQTDATSFYDRVWAAIRDKYRSEALPTDLPA 291 +++ E+ + + + E E + + + R IR++ + Sbjct: 599 EKIREQEEMTQEQEEKMGEQEEKMCEQEEKMQEQEEKMRRQEEKIREQEKK--------- 649 Query: 292 PSAPDLTEPKEEQPPVPSSPTEEEEEEEEEEEEEAEE----EEEEEDSEEAPPPLSPPQP 347 + E +E+ E+EE+ E+EE+ E+ +E+EE + + Sbjct: 650 -----IREQEEKIREQEEMMQEQEEKMWEQEEKMCEQEEKMQEQEEKMRRQEEKMWEQEV 704 Query: 348 ASPAEEDKMPPYDEQTQAFI 367 +E+KM + E +A I Sbjct: 705 RLRQQEEKMQEHQEHLEAAI 724 Score = 35.0 bits (79), Expect = 0.17 Identities = 25/102 (24%), Positives = 47/102 (46%), Gaps = 9/102 (8%) Query: 297 LTEPKEEQPPVPSSPTEEEEEEEEEEEEEAEEEEEEEDSEEAPPPLSPPQPASPAEEDKM 356 L + +EE+ +E EE+ +E+EE+ E+EE+ +E +E+ M Sbjct: 355 LNQQQEEKMWRQEEKIQEWEEKIQEQEEKIREQEEKIREQEEK---------MRRQEEMM 405 Query: 357 PPYDEQTQAFIDAAQEARNKFEEAERSLKDMEESIRNLEQEI 398 +E+ + + E K E + + EE IR LE+++ Sbjct: 406 WEKEEKMRRQEEMMWEKEEKMRRQEEMMWEKEEKIRELEEKM 447 >gi|148746195 trichohyalin [Homo sapiens] Length = 1943 Score = 55.5 bits (132), Expect = 1e-07 Identities = 66/306 (21%), Positives = 126/306 (41%), Gaps = 19/306 (6%) Query: 113 ENTCKEKGRKERESLQQMAEVTR-EGFRLKKILIEDWKKAREEKQKKLIELQAGKKSLED 171 E K + + R+ L++ E R E R K+ L D ++ R E+ KL E + ++ E Sbjct: 444 EQRLKREQEERRDWLKREEETERHEQERRKQQLKRDQEEERRERWLKLEE-EERREQQER 502 Query: 172 QVEMLRTVKEEAEKPEREAKEQHQKLWEEQLAAAKAQQEQELAADAFKELDDDMDGTVSV 231 + + LR +EE + + +E+ ++L + + + ++EQE + + +++ Sbjct: 503 REQQLRREQEERREQRLKRQEEEERLQQRLRSEQQLRREQEERREQLLKREEEKRLEQER 562 Query: 232 TELQTHPELDTDGDGAL--SEAEAQALLSGDTQTDATSFYDR--VWAAIRDKYRSEALPT 287 E + E + D L E Q L + + R V +++ R + L Sbjct: 563 REQRLKREQEERRDQLLKREEERRQQRLKREQEERLEQRLKREEVERLEQEERREQRLKR 622 Query: 288 DLPAPSAPDLTEPKEEQPPVPSSPTEEEEEEEEEEEEEAEEEEE----------EEDSEE 337 + P EEQ E++E E+ + EEEEE EE+ E Sbjct: 623 EEPEEERRQQLLKSEEQEERRQQQLRREQQERREQRLKREEEEERLEQRLKREHEEERRE 682 Query: 338 APPPLSPPQPASPAEEDKMPPYDEQTQAFIDAAQE---ARNKFEEAERSLKDMEESIRNL 394 + A + ++P + Q ++ DA Q +R + +E +R ++ EE R Sbjct: 683 QELAEEEQEQARERIKSRIPKWQWQLESEADARQSKVYSRPRKQEGQRRRQEQEEKRRRR 742 Query: 395 EQEISF 400 E E+ + Sbjct: 743 ESELQW 748 Score = 48.1 bits (113), Expect = 2e-05 Identities = 60/289 (20%), Positives = 119/289 (41%), Gaps = 18/289 (6%) Query: 117 KEKGRKERESLQQMAEVTREGFRLKKILIEDWKKAREEKQKKLIELQAGKKSLEDQVEML 176 KE+ + + E Q+ E+ E +L+K+ ++ ++ R+E++++ L+ ++ L + E Sbjct: 255 KEEEKLQEEEPQRQRELQEEEEQLRKLERQELRRERQEEEQQQQRLRR-EQQLRRKQEEE 313 Query: 177 RTVKEEAEKPEREAKEQHQKLWEEQLAAAKAQQEQELAADAFKELDDDMDGTVSVTELQT 236 R ++E + ++E +EQ ++ E+QL + +QE+ +E +++ E Q Sbjct: 314 RREQQEERREQQERREQQEERREQQL---RREQEERREQQLRREQEEER------REQQL 364 Query: 237 HPELDTDGDGALSEAEAQALLSGDTQTDATSFYDRVWAAIRDKYRSEALPTDLPAPSAPD 296 E + + E Q + + ++ + R + L + Sbjct: 365 RREQEEERREQQLRREQQLRREQQLRREQQLRREQQLRREQQLRREQQLRREQQLRREQQ 424 Query: 297 LTEPKEEQPPVPSSPTEEEEEEEEEEEEE------AEEEEEEEDSEEAPPPLSPPQPASP 350 L +EE+ E E+ + E+EE EEE E + E L Q Sbjct: 425 LRREQEEERHEQKHEQERREQRLKREQEERRDWLKREEETERHEQERRKQQLKRDQEEER 484 Query: 351 AEE-DKMPPYDEQTQAFIDAAQEARNKFEEAERSLKDMEESIRNLEQEI 398 E K+ + + Q Q R + E E+ LK EE R L+Q + Sbjct: 485 RERWLKLEEEERREQQERREQQLRREQEERREQRLKRQEEEER-LQQRL 532 Score = 47.8 bits (112), Expect = 3e-05 Identities = 57/298 (19%), Positives = 121/298 (40%), Gaps = 28/298 (9%) Query: 117 KEKGRKERESLQQMAEVTREGFRLKKILIEDWKKAREEKQKKLIELQAGKKSLEDQVEML 176 K++ R+ER+ E +E + + +L ++ +K +EE+ ++ ELQ E++ ++ Sbjct: 226 KQQQRRERQDRVFQEEEEKEWRKRETVLRKEEEKLQEEEPQRQRELQ------EEEEQLR 279 Query: 177 RTVKEEAEKPEREAKEQHQKLWEEQLAAAKAQQEQELAADAFKELDDDMDGTVSVTELQT 236 + ++E + +E ++Q Q+L EQ K ++E+ + +E + + E Q Sbjct: 280 KLERQELRRERQEEEQQQQRLRREQQLRRKQEEERREQQEERREQQERREQQEERREQQL 339 Query: 237 HPELDTDGDGAL----SEAEAQALLSGDTQTDATSFYDRVWAAIRDKY---------RSE 283 E + + L E + L + + + R +R + R + Sbjct: 340 RREQEERREQQLRREQEEERREQQLRREQEEERREQQLRREQQLRREQQLRREQQLRREQ 399 Query: 284 ALPTDLPAPSAPDLTEPKEEQPPVPSSPTEEEEEEEEEEEEEAEEEEEEEDSEEAPPPLS 343 L + L ++ + +EEE E++ E+E E+ + + EE L Sbjct: 400 QLRREQQLRREQQLRREQQLRREQQLRREQEEERHEQKHEQERREQRLKREQEERRDWLK 459 Query: 344 PPQPASPAEEDKMPPYDEQTQAFIDAAQEARNKF----EEAERSLKDMEESIRNLEQE 397 + E+++ + Q D +E R ++ EE R ++ E EQE Sbjct: 460 REEETERHEQER-----RKQQLKRDQEEERRERWLKLEEEERREQQERREQQLRREQE 512 Score = 45.4 bits (106), Expect = 1e-04 Identities = 70/304 (23%), Positives = 124/304 (40%), Gaps = 33/304 (10%) Query: 117 KEKGRKERESLQQMAEVTREGFRLKKILIEDWKKAREEKQ-----KKLIELQAGKKSLED 171 +E+ RKE++ LQ+ E + R K+ E ++ REE+Q ++L+ + K+ ++ Sbjct: 896 QEQLRKEQQLLQEEEEELQREEREKRRRQEQERQYREEEQLQQEEEQLLREEREKRRRQE 955 Query: 172 QVEMLRT-----VKEE---AEKPEREAKEQHQKLWEEQLAAAKAQQEQELAADAFKELDD 223 + R KEE E+PE+ +++ +K + E+ + ++EQ L + K Sbjct: 956 RERQYRKDKKLQQKEEQLLGEEPEKRRRQEREKKYREE-EELQQEEEQLLREEREKRRRQ 1014 Query: 224 DMDGTV-SVTELQTHPEL---DTDGDGALSEAEAQALLSGDTQTDATSFYD-----RVWA 274 + + ELQ E + L E E Q + Q + R Sbjct: 1015 EWERQYRKKDELQQEEEQLLREEREKRRLQERERQYREEEELQQEEEQLLGEERETRRRQ 1074 Query: 275 AIRDKYRSEALPTDLPAPSAPDLTE-PKEEQPPVPSSPTEEEEEEEEEEEEEAEEEEEEE 333 + +YR E +L L E P++ + EEEE ++EEE+ EE E+ Sbjct: 1075 ELERQYRKEE---ELQQEEEQLLREEPEKRRRQERERQCREEEELQQEEEQLLREEREKR 1131 Query: 334 DSEEAPPPLSPPQPASPAEEDKMPPYDEQTQAFIDAAQEARNKFEEAERSLKDMEESIRN 393 +E + EE + E+ + QE ++ E E L+ EE + Sbjct: 1132 RRQELERQYREEEEVQQEEEQLLREEPEKRR-----RQELERQYRE-EEELQQEEEQLLR 1185 Query: 394 LEQE 397 EQE Sbjct: 1186 EEQE 1189 Score = 45.1 bits (105), Expect = 2e-04 Identities = 65/280 (23%), Positives = 117/280 (41%), Gaps = 37/280 (13%) Query: 117 KEKGRKERESLQQMAEVTREGFRLKKILIEDWKKAREEKQKKLIELQAGKKSLEDQVEML 176 +E+ R+ERE QQ++ R+ +K +E+ K R+E+++K +ED+ ++ Sbjct: 1560 EEQLRQEREE-QQLSRQERD----RKFRLEEQKVRRQEQERKF---------MEDEQQLR 1605 Query: 177 RTVKEEAEKPEREAKEQHQKLWEEQLAAAKAQQEQELAADAFKELDDDMDGTVSVTELQT 236 R ++ + ER+ K + +EQL + +Q+ K L+++ + + Sbjct: 1606 RQEGQQQLRQERDRKFRE----DEQLLQEREEQQLHRQERDRKFLEEE----PQLRRQER 1657 Query: 237 HPELDTDGDGALSEAEAQALLSGDTQTDATSFYDRVWAAIRDKYRSEALPTDLPAPSAPD 296 +L D D E E Q L G+ Q DR K+R E Sbjct: 1658 EQQLRHDRDRKFRE-EEQLLQEGEEQQLRRQERDR-------KFREEEQQLRRQERERKF 1709 Query: 297 LTEPKE-EQPPVPSSPTEEEEEEEEEEEEEAEEEEEEED--SEEAPPPLSPPQPASPAEE 353 L E ++ + + EEE+ +E E+E+ +E EE P Q E Sbjct: 1710 LQEEQQLRRQELERKFREEEQLRQETEQEQLRRQERYRKILEEEQLRPEREEQQLRRQER 1769 Query: 354 DKMPPYDEQTQAFID----AAQEARNKFEEAERSLKDMEE 389 D+ +EQ + + +QE+ KF E E+ ++ EE Sbjct: 1770 DRKFREEEQLRQEREEQQLRSQESDRKFREEEQLRQEREE 1809 Score = 44.3 bits (103), Expect = 3e-04 Identities = 63/289 (21%), Positives = 113/289 (39%), Gaps = 43/289 (14%) Query: 122 KERESLQQMAEVTREGFRLKKILIEDWKKAREEKQKKLIELQAGKKSLEDQVEMLRTVKE 181 +ER QQ E R F W+ EEK ++ + + + L +Q E +E Sbjct: 751 EERAHRQQQEEEQRRDFT--------WQWQAEEKSERGRQRLSARPPLREQRERQLRAEE 802 Query: 182 EAEKPEREAKEQHQKLWEEQLAAAKAQQEQELAADAFKELDDDMDGTVSVTELQTHPE-L 240 ++ +R E+ +K EQ + ++E+EL F E ++ + +LQ + L Sbjct: 803 RQQREQRFLPEEEEK---EQRRRQRREREKELQ---FLEEEEQLQRRERAQQLQEEEDGL 856 Query: 241 DTDGDGALSEAEAQALLSGDTQTDATSFYDRVWAAIRDKYRSEALPTDLPAPSAPD---- 296 D + S+ + + D+ W ++ R T P+ + Sbjct: 857 QEDQERRRSQEQRR---------------DQKWRWQLEEERKRRRHTLYAKPALQEQLRK 901 Query: 297 ----LTEPKEE-QPPVPSSPTEEEEEEEEEEEEEAEEEEEEEDSEEAPPPLSPPQPASPA 351 L E +EE Q +E+E + EEE+ ++EEE+ EE + Sbjct: 902 EQQLLQEEEEELQREEREKRRRQEQERQYREEEQLQQEEEQLLREEREKRRRQERERQYR 961 Query: 352 EEDKMPPYDEQ---TQAFIDAAQEARNKFEEAERSLKDMEESIRNLEQE 397 ++ K+ +EQ + QE K+ E E L+ EE + E+E Sbjct: 962 KDKKLQQKEEQLLGEEPEKRRRQEREKKYRE-EEELQQEEEQLLREERE 1009 Score = 42.0 bits (97), Expect = 0.001 Identities = 59/281 (20%), Positives = 119/281 (42%), Gaps = 27/281 (9%) Query: 117 KEKGRKERESLQQMAEVTREGFRLKKILIEDWKKAREEKQKKLIELQAGKKSLEDQVEML 176 + + +K R L++ + R K L E +K ++ Q++ ELQ ++ + E Sbjct: 868 QRRDQKWRWQLEEERKRRRHTLYAKPALQEQLRKEQQLLQEEEEELQREEREKRRRQEQE 927 Query: 177 RTVKEEAEKPEREAKEQHQKLWEEQLAAAKAQQEQELAAD-AFKELDDDMDGTVSVTELQ 235 R +EE E+ +E+ Q L EE+ + ++E++ D ++ ++ + G + Sbjct: 928 RQYREE----EQLQQEEEQLLREEREKRRRQERERQYRKDKKLQQKEEQLLGEEPEKRRR 983 Query: 236 THPELDTDGDGALSEAEAQALLSGDTQTDATSFYDRVWAAIRDKYRSEALPTDLPAPSAP 295 E + L + E Q LL + + ++R +YR + +L Sbjct: 984 QEREKKYREEEELQQEEEQ-LLREEREKRRRQEWER-------QYRKK---DELQQEEEQ 1032 Query: 296 DLTEPKEEQPPVPSSPTEEEEEEEEEEEEEAEEEEEEEDSEEAPPPLSPPQPASPAEEDK 355 L E +E++ +E E + EEEE ++EEE+ EE +E++ Sbjct: 1033 LLREEREKR-------RLQERERQYREEEELQQEEEQLLGEERETRRRQELERQYRKEEE 1085 Query: 356 MPPYDEQTQAFIDAAQEARNKFEEAERSLKDMEESIRNLEQ 396 + +EQ + + + + +E ER ++ EE + EQ Sbjct: 1086 LQQEEEQ----LLREEPEKRRRQERERQCREEEELQQEEEQ 1122 Score = 41.2 bits (95), Expect = 0.002 Identities = 60/294 (20%), Positives = 114/294 (38%), Gaps = 34/294 (11%) Query: 119 KGRKERESLQQMAEVTREGFRLKKILIEDWKKAREEKQKKLI-----ELQAGKKSLEDQV 173 K +E E L+Q + E R ++ L E+ ++ E+ K I +L++ + + +V Sbjct: 660 KREEEEERLEQRLKREHEEERREQELAEEEQEQARERIKSRIPKWQWQLESEADARQSKV 719 Query: 174 EMLRTVKEEAEKPEREAKEQHQKL-----WEEQLAAAKAQQEQELAADAFKELDDDMDGT 228 R K+E ++ +E +E+ ++ W+E+ A + QQE+E D + + Sbjct: 720 YS-RPRKQEGQRRRQEQEEKRRRRESELQWQEEERAHRQQQEEEQRRDFTWQWQAEEKSE 778 Query: 229 VSVTELQTHPELDTDGDGALSEAEAQALLSGDTQTDATSFYDRVWAAIRDKYRSEALPTD 288 L P L + L E Q Q + + R + R E Sbjct: 779 RGRQRLSARPPLREQRERQLRAEERQ-------QREQRFLPEEEEKEQRRRQRRER---- 827 Query: 289 LPAPSAPDLTEPKEEQPPVPSSPTEEEEEEEEEEEEEAEEEEEEEDS------EEAPPPL 342 L E ++ Q + +EEE+ +E++E +E+ D EE Sbjct: 828 --EKELQFLEEEEQLQRRERAQQLQEEEDGLQEDQERRRSQEQRRDQKWRWQLEEERKRR 885 Query: 343 SPPQPASPAEEDKMPPYDEQTQAFIDAAQEARNKFEEAERSLKDMEESIRNLEQ 396 A PA ++++ + Q + +E + E +R ++ E R EQ Sbjct: 886 RHTLYAKPALQEQL----RKEQQLLQEEEEELQREEREKRRRQEQERQYREEEQ 935 Score = 40.0 bits (92), Expect = 0.005 Identities = 61/284 (21%), Positives = 116/284 (40%), Gaps = 65/284 (22%) Query: 119 KGRKERESLQQMAEVT-REGFRLKKILIEDWKKAREEKQKKLI--ELQAGKKSLEDQVEM 175 K R+E + LQ+ E R R +K E+ + R+E+++K + E Q ++ LE + Sbjct: 1668 KFREEEQLLQEGEEQQLRRQERDRKFREEEQQLRRQERERKFLQEEQQLRRQELERKFRE 1727 Query: 176 LRTVKEEAEKPEREAKEQHQKLWEEQLAAAKAQQEQELAADAFKELDDDMDGTVSVTELQ 235 +++E E+ + +E+++K+ EE+ + +++Q + ++ ++ Sbjct: 1728 EEQLRQETEQEQLRRQERYRKILEEEQLRPEREEQQLRRQERDRKFREE----------- 1776 Query: 236 THPELDTDGDGALSEAEAQALLSGDTQTDATSFYDRVWAAIRDKYRSEALPTDLPAPSAP 295 + E E Q L S ++ DR K+R E Sbjct: 1777 ---------EQLRQEREEQQLRSQES--------DR-------KFREEE----------- 1801 Query: 296 DLTEPKEEQPPVPSSPTEEE--EEEEEEEEEEAEEEEEEEDSEEAPPPLSPPQPASPAEE 353 L + +EEQ P + EEE+ + EE+ + +E D + Q S EE Sbjct: 1802 QLRQEREEQQLRPQQRDGKYRWEEEQLQLEEQEQRLRQERDRQYRAEEQFATQEKSRREE 1861 Query: 354 DKMPPYDEQTQAFIDAAQEARNKFEEAERSLKDMEESIRNLEQE 397 ++ +EQ + +E ER L+ EE IR ++E Sbjct: 1862 QELWQEEEQ------------KRRQERERKLR--EEHIRRQQKE 1891 Score = 39.7 bits (91), Expect = 0.007 Identities = 59/287 (20%), Positives = 119/287 (41%), Gaps = 24/287 (8%) Query: 116 CKEKGRKERESLQQMAEVTREGFR-LKKILIEDWKKAREEKQKKLIELQAGKKSLEDQVE 174 CK + ++ L+ R+ + L+ +L E ++ RE+++++ Q + ++ + Sbjct: 1242 CKGRENEQFRQLEDSQLRDRQSQQDLQHLLGEQQERDREQERRRW---QQRDRHFPEEEQ 1298 Query: 175 MLRTVKEEAEKPEREAKEQHQKLWEEQLAAAKAQQEQELAADAFKELDDDMDGTVSVTEL 234 + R ++EA++ +R+++E+ Q L EE+ + Q+ + + L + + + E Sbjct: 1299 LEREEQKEAKRRDRKSQEEKQLLREEREEKRRRQETDRKFREEEQLLQEREEQPLRRQER 1358 Query: 235 QT---HPELDTDGDGALSEAEAQALLSGDTQTDATSFYDRVWAAIRDKYRSEALPTDLPA 291 EL G E Q L + + + + +R + R + L D Sbjct: 1359 DRKFREEELRHQEQGRKFLEEEQRLRRQERERK----FLKEEQQLRCQEREQQLRQDR-- 1412 Query: 292 PSAPDLTEPKEEQPPVPSSPTEEEEEEEEEEEEEAEEEEEEEDSEEAPPPLSPPQPASPA 351 D +EEQ +E + + EEE++ +E E E L + Sbjct: 1413 ----DRKFREEEQ----QLSRQERDRKFREEEQQVRRQERERKFLEEEQQLRQERHRKFR 1464 Query: 352 EEDKMPPYDEQTQAFIDAAQEARNKFEEAERSLKDMEESIRNLEQEI 398 EE+++ E+ Q QE KF E E+ L+ E + EQE+ Sbjct: 1465 EEEQLLQEREEQQLH---RQERDRKFLEEEQQLRRQERDRKFREQEL 1508 Score = 39.3 bits (90), Expect = 0.009 Identities = 56/257 (21%), Positives = 105/257 (40%), Gaps = 23/257 (8%) Query: 145 IEDWKKAREEKQKKLIELQAGKKSLEDQVEMLRTVKEEAEKPEREAKEQHQKLWEEQLAA 204 +++ K+AR + ++ L++ ++ EDQ ++ E+P + +++ Q+ E +LA Sbjct: 95 LDEEKRARCDGKESLLQ---DRRQEEDQRRFEPRDRQLEEEPGQRRRQKRQEQ-ERELAE 150 Query: 205 AKAQQEQELAADAFKELDDDMDGTVSVTELQTHPELDTDGDGALSEAEAQALLSGDTQT- 263 + Q E++ + D + E Q E + E + Q+ +T+ Sbjct: 151 GEEQSEKQERLEQRDRQRRDEELWRQRQEWQEREERRAE------EEQLQSCKGHETEEF 204 Query: 264 -DATSFYDRVWAAIRDKYRSEALPTDLPAPSAPDLTEPKEEQPPVPSSPTEEEEEEEEEE 322 D R +R K R E D +EE+ T +EEE+ + Sbjct: 205 PDEEQLRRRELLELRRKGREEK---QQQRRERQDRVFQEEEEKEWRKRETVLRKEEEKLQ 261 Query: 323 EEEAEEEEEEEDSEEAPPPLSPPQPASPAEEDKMPPYDEQTQAFIDAAQEARNKFEEAER 382 EEE + + E ++ EE L + +E +EQ Q + Q+ R K EE R Sbjct: 262 EEEPQRQRELQEEEEQLRKLERQELRRERQE------EEQQQQRLRREQQLRRKQEEERR 315 Query: 383 SLKD--MEESIRNLEQE 397 ++ E+ R +QE Sbjct: 316 EQQEERREQQERREQQE 332 Score = 38.9 bits (89), Expect = 0.012 Identities = 55/286 (19%), Positives = 110/286 (38%), Gaps = 16/286 (5%) Query: 117 KEKGRKERESLQQMAEVTREGFRLKKILIEDWKKAREEKQKKLIELQAGKKSLEDQVEML 176 +++ R E Q E +E R + E+ + REE+++K + +K E++ + Sbjct: 1287 QQRDRHFPEEEQLEREEQKEAKRRDRKSQEEKQLLREEREEKRRRQETDRKFREEEQLLQ 1346 Query: 177 RTVKEEAEKPEREAKEQHQKLWEEQLAAAKAQQEQELAAD--AFKELDDDMDGTVSVTEL 234 ++ + ER+ K + ++L ++ ++EQ L K L ++ E Sbjct: 1347 EREEQPLRRQERDRKFREEELRHQEQGRKFLEEEQRLRRQERERKFLKEEQQLRCQEREQ 1406 Query: 235 QTHPELD---TDGDGALSEAEAQALLSGDTQTDATSFYDRVWAAIRDKYRSEALPTDLPA 291 Q + D + + LS E + Q +R + + R E Sbjct: 1407 QLRQDRDRKFREEEQQLSRQERDRKFREEEQQVRRQERERKFLEEEQQLRQE---RHRKF 1463 Query: 292 PSAPDLTEPKEEQPPVPSSPTEEEEEEEEEEEEEAEEEEEEEDSEEAPPPLSPPQPASPA 351 L + +EEQ +E + + EEE + +E D + L +P Sbjct: 1464 REEEQLLQEREEQ------QLHRQERDRKFLEEEQQLRRQERDRKFREQELRSQEPERKF 1517 Query: 352 EEDKMPPYDEQTQ-AFIDAAQEARNKFEEAERSLKDMEESIRNLEQ 396 E++ + +Q Q F+ Q+ R + E ++ +D + R EQ Sbjct: 1518 LEEEQQLHRQQRQRKFLQEEQQLRRQ-ERGQQRRQDRDRKFREEEQ 1562 Score = 37.7 bits (86), Expect = 0.026 Identities = 68/290 (23%), Positives = 119/290 (41%), Gaps = 36/290 (12%) Query: 117 KEKGRKERESLQQMAEVTREGFRLKKILIEDWKKAR----EEKQKKLIELQAGKKSLEDQ 172 +EK +E E LQQ E ++L E+ +K R E + +K ELQ ++ L + Sbjct: 986 REKKYREEEELQQEEE---------QLLREEREKRRRQEWERQYRKKDELQQEEEQLLRE 1036 Query: 173 VEMLRTVKEEAEKPEREAKEQHQKLWEEQLAAAKAQ--QEQELAADAFKELDDDMDGTVS 230 R ++E E+ RE +E Q+ EEQL + + + QEL KE + + Sbjct: 1037 EREKRRLQER-ERQYREEEELQQE--EEQLLGEERETRRRQELERQYRKEEELQQEEEQL 1093 Query: 231 VTELQTHPELDTDGDGALSEAEAQALLSGDTQTDATSFYDRVWAAIRDKYRSEALPTDLP 290 + E PE + E + L + Q R + +YR E Sbjct: 1094 LRE---EPEKRRRQERERQCREEEELQQEEEQLLREEREKRRRQELERQYREEEEVQQEE 1150 Query: 291 APSAPDLTEPKEEQPPVPSSPTEEEEEEEEEEEEEAEEEEEEEDSEEAPPPLSPPQPASP 350 + EP++ + EEEE ++EEE+ EE+E+ E + Sbjct: 1151 EQLLRE--EPEKRRRQELERQYREEEELQQEEEQLLREEQEKRRQE---------RERQY 1199 Query: 351 AEEDKMPPYDEQTQAFIDAAQEARNKFE---EAERSLKDMEESIRNLEQE 397 EE+++ ++ Q + D Q + K++ E E +++D + + E E Sbjct: 1200 REEEEL-QRQKRKQRYRDEDQRSDLKWQWEPEKENAVRDNKVYCKGRENE 1248 Score = 32.0 bits (71), Expect = 1.4 Identities = 63/311 (20%), Positives = 119/311 (38%), Gaps = 32/311 (10%) Query: 113 ENTCKEKGRKERESLQQMAEVTREG-FRLKKILIEDWKKAREEKQKKLIELQAGKKSLED 171 E +E+ + + L++ ++ RE R ++ L + + RE++ ++ +L+ ++ + Sbjct: 369 EEERREQQLRREQQLRREQQLRREQQLRREQQLRREQQLRREQQLRREQQLRREQQLRRE 428 Query: 172 QVEMLRTVKEEAEKPEREAK--EQHQKLW------------EEQLAAAKAQQEQELAADA 217 Q E K E E+ E+ K ++ ++ W E + K QE+E Sbjct: 429 QEEERHEQKHEQERREQRLKREQEERRDWLKREEETERHEQERRKQQLKRDQEEERRERW 488 Query: 218 FKELDDDMDGTVSVTELQTHPELDTDGDGALSEAEAQALLSGDTQTDATSFYDRVWAAIR 277 K +++ E Q E + + L E + L +++ + + Sbjct: 489 LKLEEEERREQQERREQQLRREQEERREQRLKRQEEEERLQQRLRSEQQLRRE------Q 542 Query: 278 DKYRSEALPTDLPAPSAPDLTEP--KEEQPPVPSSPTEEEEE--------EEEEEEEEAE 327 ++ R + L + + E K EQ + EEE E+EE E+ Sbjct: 543 EERREQLLKREEEKRLEQERREQRLKREQEERRDQLLKREEERRQQRLKREQEERLEQRL 602 Query: 328 EEEEEEDSEEAPPPLSPPQPASPAEEDKMPPYDEQTQAFIDAAQEARNKFEEAERSLKDM 387 + EE E E+ + P EE + + Q Q R + E E+ LK Sbjct: 603 KREEVERLEQEERREQRLKREEPEEERRQQLLKSEEQEERRQQQLRREQQERREQRLKRE 662 Query: 388 EESIRNLEQEI 398 EE R LEQ + Sbjct: 663 EEEER-LEQRL 672 Score = 29.3 bits (64), Expect = 9.3 Identities = 29/146 (19%), Positives = 63/146 (43%), Gaps = 17/146 (11%) Query: 119 KGRKERESLQQMAEVTREGFRLKKILIEDWKKAREEKQKKLIELQAGKK--------SLE 170 K R+E + Q+ E + E+ + +E ++++L Q K LE Sbjct: 1772 KFREEEQLRQEREEQQLRSQESDRKFREEEQLRQEREEQQLRPQQRDGKYRWEEEQLQLE 1831 Query: 171 DQVEMLRTVK------EEAEKPEREAKEQHQKLWEEQLAAAKAQQEQELAADAFKELDDD 224 +Q + LR + EE + +++ + Q+LW+E+ + ++E++L + + + Sbjct: 1832 EQEQRLRQERDRQYRAEEQFATQEKSRREEQELWQEEEQKRRQERERKLREEHIRRQQKE 1891 Query: 225 MDGTVSVTELQTHPELDTDGDGALSE 250 V E+++ + G G L E Sbjct: 1892 EQRHRQVGEIKSQ---EGKGHGRLLE 1914 >gi|24307879 dynein, cytoplasmic 1, intermediate chain 2 [Homo sapiens] Length = 638 Score = 55.5 bits (132), Expect = 1e-07 Identities = 52/253 (20%), Positives = 105/253 (41%), Gaps = 26/253 (10%) Query: 166 KKSLEDQVEMLRTVKEEAEKPEREAKEQHQKLWEEQLAAAKAQQEQELAADAFKELDDDM 225 K LE + + L ++EE ++ E E K++ +E +A + + + E + L M Sbjct: 8 KAELERKKQRLAQIREEKKRKEEERKKKETDQKKEAVAPVQEESDLEKKRREAEALLQSM 67 Query: 226 ----DGTVSVTELQTHPELDTDGDGALSEAEAQALLSGDTQTDATSFYDRVWAAIRDKYR 281 + + +E P + + +EA + SGD + + + ++ + Sbjct: 68 GLTPESPIVFSEYWVPPPMSPSSKSVSTPSEAGSQDSGDGAVGSRTLHWDTDPSVLQLHS 127 Query: 282 SEALP-----------TDLPAPSAPDLTEPKEEQPPVPSSPTEEEEEEE---------EE 321 L T + P +T KE Q PV + P E+EEE++ E Sbjct: 128 DSDLGRGPIKLGMAKITQVDFPPREIVTYTKETQTPVMAQPKEDEEEDDDVVAPKPPIEP 187 Query: 322 EEEEAEEEEEEEDSEEAPPPLSPPQPASPAEEDKMPPYDEQTQAFIDAA--QEARNKFEE 379 EEE+ +++EE DS+ P L+ + ++ + + + ++ A ++ F+ Sbjct: 188 EEEKTLKKDEENDSKAPPHELTEEEKQQILHSEEFLSFFDHSTRIVERALSEQINIFFDY 247 Query: 380 AERSLKDMEESIR 392 + R L+D E I+ Sbjct: 248 SGRDLEDKEGEIQ 260 >gi|222446603 golgi autoantigen, golgin subfamily a-like [Homo sapiens] Length = 668 Score = 55.1 bits (131), Expect = 2e-07 Identities = 59/293 (20%), Positives = 126/293 (43%), Gaps = 19/293 (6%) Query: 117 KEKGRKERESLQQMAEVTREGFRLKKILIEDWKKARE------EKQKKLIELQAGKKSLE 170 +EK R++ E +++ E R R ++++ E +K R EK++K+ L+ + + Sbjct: 320 EEKIREQEEKIREQEEKMR---RQEEMMWEKEEKMRRQEEMMWEKEEKMRRLE---EMMW 373 Query: 171 DQVEMLRTVKEEAEKPEREAKEQHQKLWEEQLAAAKAQQEQELAADAFKELDDDMDGTVS 230 ++ E +R ++E+ + E+ +++ ++ EE++ + +QEQE +E + + + Sbjct: 374 EKEEKIRELEEKMHEQEKIREQEEKRQEEEKIREQEKRQEQEAKMWRQEEKIREQEEKIR 433 Query: 231 VTE--LQTHPELDTDGDGALSEAEAQALLSGDTQTDATSFYDRVWAAI-----RDKYRSE 283 E + E + + E + Q Q + + +W ++K R + Sbjct: 434 EQEKKMWRQEEKIHEQEKIREEEKRQEQEEMWRQEEKIREQEEIWRQKEKMHEQEKIRKQ 493 Query: 284 ALPTDLPAPSAPDLTEPKEEQPPVPSSPTEEEEEEEEEEEEEAEEEEEEEDSEEAPPPLS 343 D E EQ E+ E+EE+ E+ E+ E+E+ + Sbjct: 494 EEKVWRQEEKMHDQEEKIREQEEKMWRQEEKIREQEEKIREQEEKIREQEEMMQEQEEKM 553 Query: 344 PPQPASPAEEDKMPPYDEQTQAFIDAAQEARNKFEEAERSLKDMEESIRNLEQ 396 Q E++KM +E+ + + +E + K E E + + EE IR E+ Sbjct: 554 GEQEEKMQEQEKMRRQEEKIREQEEKIREQKEKIREQEEKIWEQEEKIREQEE 606 Score = 54.7 bits (130), Expect = 2e-07 Identities = 56/291 (19%), Positives = 126/291 (43%), Gaps = 18/291 (6%) Query: 117 KEKGRKERESLQQMAEVTREGFRLKKILIEDWK-KAREEKQKKLIELQAGKKSLEDQVEM 175 +EK R+ E + + E RE L++ + E K + +EEK+++ +++ +K E + +M Sbjct: 362 EEKMRRLEEMMWEKEEKIRE---LEEKMHEQEKIREQEEKRQEEEKIREQEKRQEQEAKM 418 Query: 176 LRTVKEEAEKPEREAKEQHQKLW--------EEQLAAAKAQQEQELAADAFKELDDDMDG 227 R +E+ + E + +EQ +K+W +E++ + +QEQE +++ + + Sbjct: 419 WRQ-EEKIREQEEKIREQEKKMWRQEEKIHEQEKIREEEKRQEQEEMWRQEEKIREQEEI 477 Query: 228 TVSVTELQTHPELDTDGDGALSEAEAQALLSGDTQTDATSFYDRVWAAIRDKYRSEALPT 287 ++ ++ + + E D + +++W +K R + Sbjct: 478 WRQKEKMHEQEKIRKQEEKVWRQEEKMH----DQEEKIREQEEKMWRQ-EEKIREQEEKI 532 Query: 288 DLPAPSAPDLTEPKEEQPPVPSSPTEEEEEEEEEEEEEAEEEEEEEDSEEAPPPLSPPQP 347 + E +EQ E+ +E+E+ +E + E+EE E + + Sbjct: 533 REQEEKIREQEEMMQEQEEKMGEQEEKMQEQEKMRRQEEKIREQEEKIREQKEKIREQEE 592 Query: 348 ASPAEEDKMPPYDEQTQAFIDAAQEARNKFEEAERSLKDMEESIRNLEQEI 398 +E+K+ +E Q + E K E E +++ EE +R E+++ Sbjct: 593 KIWEQEEKIREQEEMMQEQEEKMWEQEEKMCEQEEKMQEQEEKMRRQEEKM 643 Score = 54.3 bits (129), Expect = 3e-07 Identities = 55/321 (17%), Positives = 128/321 (39%), Gaps = 22/321 (6%) Query: 122 KERESLQQMAEVTREGFRLKKILIEDWKKAREEKQKKLIELQAGKKSLEDQVEMLRTVKE 181 +E E ++ + E ++ I++W++ +E+++K+ E + + + +Q E +R +E Sbjct: 286 EENELWNRLNQQQEEKMWRQEEKIQEWEEKIQEQEEKIREQE---EKIREQEEKMRRQEE 342 Query: 182 EAEKPEREAKEQHQKLWEEQLAAAKAQQEQELAADAFKELDDDMDGTVSVTELQTHPELD 241 + E + + Q + +WE++ + ++ + +EL++ M + E Q + Sbjct: 343 MMWEKEEKMRRQEEMMWEKEEKMRRLEEMMWEKEEKIRELEEKMHEQEKIRE-QEEKRQE 401 Query: 242 TDGDGALSEAEAQALLSGDTQTDATSFYDRVWAAIRDKYRSEALPTDLPAPSAPDLTEPK 301 + + + Q + +++ + +R E E Sbjct: 402 EEKIREQEKRQEQEAKMWRQEEKIREQEEKIREQEKKMWRQE---------------EKI 446 Query: 302 EEQPPVPSSPTEEEEEEEEEEEEEAEEEEE---EEDSEEAPPPLSPPQPASPAEEDKMPP 358 EQ + +E+EE +EE+ E+EE +++ + + +E+KM Sbjct: 447 HEQEKIREEEKRQEQEEMWRQEEKIREQEEIWRQKEKMHEQEKIRKQEEKVWRQEEKMHD 506 Query: 359 YDEQTQAFIDAAQEARNKFEEAERSLKDMEESIRNLEQEISFDFGPNGEFAYLYSQCYEL 418 +E+ + + K E E +++ EE IR E+ + GE + ++ Sbjct: 507 QEEKIREQEEKMWRQEEKIREQEEKIREQEEKIREQEEMMQEQEEKMGEQEEKMQEQEKM 566 Query: 419 TTNEYVYRLCPFKLVSQKPKL 439 E R K+ QK K+ Sbjct: 567 RRQEEKIREQEEKIREQKEKI 587 Score = 44.3 bits (103), Expect = 3e-04 Identities = 46/257 (17%), Positives = 116/257 (45%), Gaps = 40/257 (15%) Query: 113 ENTCKEKGRKERESLQQMAEVTREGFRL--KKILIEDWKKAREEKQKKLIELQAGKKSLE 170 E +E+ R+E+E + + E RE + +K + + +K R++++K + ++ + Sbjct: 450 EKIREEEKRQEQEEMWRQEEKIREQEEIWRQKEKMHEQEKIRKQEEK----VWRQEEKMH 505 Query: 171 DQVEMLRTVKEEAEKPEREAKEQHQKLWEEQLAAAKAQQEQELAADAFKELDDDMDGTVS 230 DQ E +R +E+ + E + +EQ +K+ E++ K ++++E+ + +++ + + Sbjct: 506 DQEEKIREQEEKMWRQEEKIREQEEKIREQE---EKIREQEEMMQEQEEKMGEQEEKMQE 562 Query: 231 VTELQTHPELDTDGDGALSEAEAQALLSGDTQTDATSFYDRVWAAIRDKYRSEALPTDLP 290 +++ E + + + E + + +++W +K R + Sbjct: 563 QEKMRRQEEKIREQEEKIREQKEKI----------REQEEKIWEQ-EEKIREQE------ 605 Query: 291 APSAPDLTEPKEEQPPVPSSPTEEEEEEEEEEEEEAEEEEEEEDSEEAPPPLSPPQPASP 350 ++ + +EE+ E+EE+ +E+EE+ +EE+ +E Sbjct: 606 -----EMMQEQEEKMWEQEEKMCEQEEKMQEQEEKMRRQEEKMWEQEV---------RLR 651 Query: 351 AEEDKMPPYDEQTQAFI 367 +E+KM + E +A I Sbjct: 652 QQEEKMQEHQEHLEAAI 668 >gi|157738649 neurofilament, medium polypeptide 150kDa isoform 1 [Homo sapiens] Length = 916 Score = 55.1 bits (131), Expect = 2e-07 Identities = 74/298 (24%), Positives = 128/298 (42%), Gaps = 42/298 (14%) Query: 111 ICENTCKEKGRKERESLQQMAEVTREGFRLKKILIEDWKKAREEKQKK--LIELQAGKKS 168 I E T E + E E + + +T E L + E+ K+A EEK+++ E + K Sbjct: 456 IIEETKVEDEKSEME--EALTAITEE---LAVSMKEEKKEAAEEKEEEPEAEEEEVAAKK 510 Query: 169 LEDQVEMLRTVKEEAEKPEREAKEQHQKLWEEQLAAAKAQQEQELAADAFKELDDDMDGT 228 + +EE EK E E +E+ EE+ AK+ Q +E ++ +G+ Sbjct: 511 SPVKATAPEVKEEEGEKEEEEGQEEE----EEEDEGAKSDQAEEGGSEK--------EGS 558 Query: 229 VSVTELQTHPELDTDGDGALSEAEAQALLSGDTQTDATSFYDRVWAAIRDKYRSEALPTD 288 S E E +T+ + EAEA+ + +++ + + + A + + +A Sbjct: 559 -SEKEEGEQEEGETEAEAEGEEAEAKEEKKVEEKSEEVATKEELVADAKVEKPEKAKS-- 615 Query: 289 LPAPSAPDLTEPKEEQP----------PVPSSPTEEE------EEEEEEEEEEAEEEEEE 332 P P +P + K P PVP SP EE+ + EE+ + + Sbjct: 616 -PVPKSPVEEKGKSPVPKSPVEEKGKSPVPKSPVEEKGKSPVPKSPVEEKGKSPVSKSPV 674 Query: 333 EDSEEAPPPLSPPQPA-SPAEEDKMPPYDEQTQAFIDAAQEARNKFEEAERSLKDMEE 389 E+ ++P P SP + A S AE K +E+ + +A +E K E+ E KD+ E Sbjct: 675 EEKAKSPVPKSPVEEAKSKAEVGKGEQKEEEEKEVKEAPKE--EKVEKKEEKPKDVPE 730 Score = 49.7 bits (117), Expect = 7e-06 Identities = 69/310 (22%), Positives = 129/310 (41%), Gaps = 39/310 (12%) Query: 127 LQQMAEVTREGFRLKKILIEDWKKAREEKQKKLIELQAGKKSLEDQVEM--------LRT 178 L + AE +E R K I ++++ + K +L ++ K+SLE Q+ L + Sbjct: 299 LTEAAEQNKEAIRSAKEEIAEYRRQLQSKSIELESVRGTKESLERQLSDIEERHNHDLSS 358 Query: 179 VKEEAEKPEREAK------EQHQKLWEEQLAAAKAQQEQELAADAFKELDDDMDGTV--S 230 ++ ++ E E + +H + +++ L A + A E ++ T S Sbjct: 359 YQDTIQQLENELRGTKWEMARHLREYQDLLNVKMALDIEIAAYRKLLEGEETRFSTFAGS 418 Query: 231 VT-ELQTH-PELDTDGDGALSEAEA----------QALLSGDTQTDATSFYDRVWAAIRD 278 +T L TH P + + EA + ++ D S + AI + Sbjct: 419 ITGPLYTHRPPITISSKIQKPKVEAPKLKVQHKFVEEIIEETKVEDEKSEMEEALTAITE 478 Query: 279 KY-------RSEALPTDLPAPSAPDLTEPKEEQPPVPSSPTEEEEEEEEEEEEEAEEEEE 331 + + EA P A + ++ P ++P +EEE E+EEEE EEEEE Sbjct: 479 ELAVSMKEEKKEAAEEKEEEPEAEEEEVAAKKSPVKATAPEVKEEEGEKEEEEGQEEEEE 538 Query: 332 EED---SEEAPPPLSPPQPASPAEEDKMPPYDEQTQAFIDAAQ-EARNKFEEAERSLKDM 387 E++ S++A S + +S EE + + + +A + A+ + K EE + Sbjct: 539 EDEGAKSDQAEEGGSEKEGSSEKEEGEQEEGETEAEAEGEEAEAKEEKKVEEKSEEVATK 598 Query: 388 EESIRNLEQE 397 EE + + + E Sbjct: 599 EELVADAKVE 608 Score = 49.7 bits (117), Expect = 7e-06 Identities = 66/277 (23%), Positives = 112/277 (40%), Gaps = 59/277 (21%) Query: 117 KEKGRKERESLQQMAEVTREGFRLKKILI---------EDWKKAREEKQKKLIELQAGKK 167 KE+ ++ E ++ E E KK + E+ +K EE Q++ E G K Sbjct: 485 KEEKKEAAEEKEEEPEAEEEEVAAKKSPVKATAPEVKEEEGEKEEEEGQEEEEEEDEGAK 544 Query: 168 SLEDQVEMLRTVKEEAEKPEREAKEQHQKLWEEQLAAAKAQQEQELAADAFKELDDDMDG 227 S DQ E + KE + + E +E+ + E + A+A++E+++ + Sbjct: 545 S--DQAEEGGSEKEGSSEKEEGEQEEGETEAEAEGEEAEAKEEKKVEEKS---------- 592 Query: 228 TVSVTELQTHPELDTDGDGALSEAEAQALLSGDTQTDATSFYDRVWAAIRDKYRSEALPT 287 E+ T EL D E + + S + + + +K +S + Sbjct: 593 ----EEVATKEELVADAKVEKPEKAKSPVPKSPVEEKGKSPVPK--SPVEEKGKSPVPKS 646 Query: 288 DL------PAPSAPDLTEPKEEQP------------PVPSSPTEE-----------EEEE 318 + P P +P E K + P PVP SP EE ++EE Sbjct: 647 PVEEKGKSPVPKSP--VEEKGKSPVSKSPVEEKAKSPVPKSPVEEAKSKAEVGKGEQKEE 704 Query: 319 EEEEEEEAEEEEEEEDSEEAPPPLSPPQPA-SPAEED 354 EE+E +EA +EE+ E EE P + + A SP +E+ Sbjct: 705 EEKEVKEAPKEEKVEKKEEKPKDVPEKKKAESPVKEE 741 Score = 35.8 bits (81), Expect = 0.099 Identities = 54/265 (20%), Positives = 103/265 (38%), Gaps = 27/265 (10%) Query: 146 EDWKKAREEKQKKLIELQAGKKSLEDQVEMLRTVKEEAEKPEREAKEQHQKLWEEQLAAA 205 E+W K R K + + E E +R+ KEE + R+ + + +L E + Sbjct: 289 EEWFKCRYAKLTE---------AAEQNKEAIRSAKEEIAEYRRQLQSKSIEL--ESVRGT 337 Query: 206 KAQQEQELAADAFKELDDDMDGTVSVTELQTHPELDTDGDGALSEAEAQALLSGDTQTDA 265 K E++L+ D + + D+ + + T + A E Q LL+ D Sbjct: 338 KESLERQLS-DIEERHNHDLSSYQDTIQQLENELRGTKWEMARHLREYQDLLNVKMALDI 396 Query: 266 T-SFYDRVWAAIRDKYRSEA--LPTDLPAPSAPDLTEPKEEQPPVPSSPTEEEEEEEEEE 322 + Y ++ ++ + A + L P K ++P V + + + + EE Sbjct: 397 EIAAYRKLLEGEETRFSTFAGSITGPLYTHRPPITISSKIQKPKVEAPKLKVQHKFVEEI 456 Query: 323 EEEAEEEEEEEDSEEAPPPLSPPQPASPAEEDKMPPYDEQTQAFIDAAQEARNKFEEAER 382 EE + E+E+ + EEA ++ S EE K +AA+E + E E Sbjct: 457 IEETKVEDEKSEMEEALTAITEELAVSMKEEKK------------EAAEEKEEEPEAEEE 504 Query: 383 SLKDMEESIRNLEQEISFDFGPNGE 407 + + ++ E+ + G E Sbjct: 505 EVAAKKSPVKATAPEVKEEEGEKEE 529 >gi|157738641 neurofilament, medium polypeptide 150kDa isoform 2 [Homo sapiens] Length = 540 Score = 55.1 bits (131), Expect = 2e-07 Identities = 74/298 (24%), Positives = 128/298 (42%), Gaps = 42/298 (14%) Query: 111 ICENTCKEKGRKERESLQQMAEVTREGFRLKKILIEDWKKAREEKQKK--LIELQAGKKS 168 I E T E + E E + + +T E L + E+ K+A EEK+++ E + K Sbjct: 80 IIEETKVEDEKSEME--EALTAITEE---LAVSMKEEKKEAAEEKEEEPEAEEEEVAAKK 134 Query: 169 LEDQVEMLRTVKEEAEKPEREAKEQHQKLWEEQLAAAKAQQEQELAADAFKELDDDMDGT 228 + +EE EK E E +E+ EE+ AK+ Q +E ++ +G+ Sbjct: 135 SPVKATAPEVKEEEGEKEEEEGQEEE----EEEDEGAKSDQAEEGGSEK--------EGS 182 Query: 229 VSVTELQTHPELDTDGDGALSEAEAQALLSGDTQTDATSFYDRVWAAIRDKYRSEALPTD 288 S E E +T+ + EAEA+ + +++ + + + A + + +A Sbjct: 183 -SEKEEGEQEEGETEAEAEGEEAEAKEEKKVEEKSEEVATKEELVADAKVEKPEKAKS-- 239 Query: 289 LPAPSAPDLTEPKEEQP----------PVPSSPTEEE------EEEEEEEEEEAEEEEEE 332 P P +P + K P PVP SP EE+ + EE+ + + Sbjct: 240 -PVPKSPVEEKGKSPVPKSPVEEKGKSPVPKSPVEEKGKSPVPKSPVEEKGKSPVSKSPV 298 Query: 333 EDSEEAPPPLSPPQPA-SPAEEDKMPPYDEQTQAFIDAAQEARNKFEEAERSLKDMEE 389 E+ ++P P SP + A S AE K +E+ + +A +E K E+ E KD+ E Sbjct: 299 EEKAKSPVPKSPVEEAKSKAEVGKGEQKEEEEKEVKEAPKE--EKVEKKEEKPKDVPE 354 Score = 49.7 bits (117), Expect = 7e-06 Identities = 66/277 (23%), Positives = 112/277 (40%), Gaps = 59/277 (21%) Query: 117 KEKGRKERESLQQMAEVTREGFRLKKILI---------EDWKKAREEKQKKLIELQAGKK 167 KE+ ++ E ++ E E KK + E+ +K EE Q++ E G K Sbjct: 109 KEEKKEAAEEKEEEPEAEEEEVAAKKSPVKATAPEVKEEEGEKEEEEGQEEEEEEDEGAK 168 Query: 168 SLEDQVEMLRTVKEEAEKPEREAKEQHQKLWEEQLAAAKAQQEQELAADAFKELDDDMDG 227 S DQ E + KE + + E +E+ + E + A+A++E+++ + Sbjct: 169 S--DQAEEGGSEKEGSSEKEEGEQEEGETEAEAEGEEAEAKEEKKVEEKS---------- 216 Query: 228 TVSVTELQTHPELDTDGDGALSEAEAQALLSGDTQTDATSFYDRVWAAIRDKYRSEALPT 287 E+ T EL D E + + S + + + +K +S + Sbjct: 217 ----EEVATKEELVADAKVEKPEKAKSPVPKSPVEEKGKSPVPK--SPVEEKGKSPVPKS 270 Query: 288 DL------PAPSAPDLTEPKEEQP------------PVPSSPTEE-----------EEEE 318 + P P +P E K + P PVP SP EE ++EE Sbjct: 271 PVEEKGKSPVPKSP--VEEKGKSPVSKSPVEEKAKSPVPKSPVEEAKSKAEVGKGEQKEE 328 Query: 319 EEEEEEEAEEEEEEEDSEEAPPPLSPPQPA-SPAEED 354 EE+E +EA +EE+ E EE P + + A SP +E+ Sbjct: 329 EEKEVKEAPKEEKVEKKEEKPKDVPEKKKAESPVKEE 365 Score = 46.6 bits (109), Expect = 6e-05 Identities = 34/121 (28%), Positives = 59/121 (48%), Gaps = 4/121 (3%) Query: 281 RSEALPTDLPAPSAPDLTEPKEEQPPVPSSPTEEEEEEEEEEEEEAEEEEEEED---SEE 337 + EA P A + ++ P ++P +EEE E+EEEE EEEEEE++ S++ Sbjct: 112 KKEAAEEKEEEPEAEEEEVAAKKSPVKATAPEVKEEEGEKEEEEGQEEEEEEDEGAKSDQ 171 Query: 338 APPPLSPPQPASPAEEDKMPPYDEQTQAFIDAAQ-EARNKFEEAERSLKDMEESIRNLEQ 396 A S + +S EE + + + +A + A+ + K EE + EE + + + Sbjct: 172 AEEGGSEKEGSSEKEEGEQEEGETEAEAEGEEAEAKEEKKVEEKSEEVATKEELVADAKV 231 Query: 397 E 397 E Sbjct: 232 E 232 Score = 44.3 bits (103), Expect = 3e-04 Identities = 29/114 (25%), Positives = 48/114 (42%), Gaps = 10/114 (8%) Query: 296 DLTEPKEEQPPV----------PSSPTEEEEEEEEEEEEEAEEEEEEEDSEEAPPPLSPP 345 + E KEE+P P T E +EEE E+EE E +EEEE+ +E Sbjct: 114 EAAEEKEEEPEAEEEEVAAKKSPVKATAPEVKEEEGEKEEEEGQEEEEEEDEGAKSDQAE 173 Query: 346 QPASPAEEDKMPPYDEQTQAFIDAAQEARNKFEEAERSLKDMEESIRNLEQEIS 399 + S E EQ + +A E + E+ +++ E + E+ ++ Sbjct: 174 EGGSEKEGSSEKEEGEQEEGETEAEAEGEEAEAKEEKKVEEKSEEVATKEELVA 227 Score = 36.2 bits (82), Expect = 0.076 Identities = 26/102 (25%), Positives = 47/102 (46%), Gaps = 3/102 (2%) Query: 299 EPKEEQPPVPSSPTEE---EEEEEEEEEEEAEEEEEEEDSEEAPPPLSPPQPASPAEEDK 355 + K E ++ TEE +EE++E E +EEE E + EE SP + +P +++ Sbjct: 88 DEKSEMEEALTAITEELAVSMKEEKKEAAEEKEEEPEAEEEEVAAKKSPVKATAPEVKEE 147 Query: 356 MPPYDEQTQAFIDAAQEARNKFEEAERSLKDMEESIRNLEQE 397 +E+ + ++ K ++AE + E S E E Sbjct: 148 EGEKEEEEGQEEEEEEDEGAKSDQAEEGGSEKEGSSEKEEGE 189 Score = 30.0 bits (66), Expect = 5.4 Identities = 25/113 (22%), Positives = 46/113 (40%), Gaps = 12/113 (10%) Query: 295 PDLTEPKEEQPPVPSSPTEEEEEEEEEEEEEAEEEEEEEDSEEAPPPLSPPQPASPAEED 354 P K ++P V + + + + EE EE + E+E+ + EEA ++ S EE Sbjct: 53 PITISSKIQKPKVEAPKLKVQHKFVEEIIEETKVEDEKSEMEEALTAITEELAVSMKEEK 112 Query: 355 KMPPYDEQTQAFIDAAQEARNKFEEAERSLKDMEESIRNLEQEISFDFGPNGE 407 K +AA+E + E E + + ++ E+ + G E Sbjct: 113 K------------EAAEEKEEEPEAEEEEVAAKKSPVKATAPEVKEEEGEKEE 153 >gi|55741709 RNA binding motif protein 25 [Homo sapiens] Length = 843 Score = 54.3 bits (129), Expect = 3e-07 Identities = 68/278 (24%), Positives = 113/278 (40%), Gaps = 54/278 (19%) Query: 117 KEKGRKERESLQQMAEVTREGFRLKKILIEDWKKAREEKQKKLIELQAGKKSLEDQVEML 176 +EK R ++ E RE R ++ + ++ RE ++++ E + ED+ + Sbjct: 385 REKSRDRERERERERERERERERERE---REREREREREREREREKDKKRDREEDEEDAY 441 Query: 177 RTVKEEAEKPEREAKEQHQ-KLWE----------EQLAAAKAQQEQELAADA------FK 219 K E + E+EA Q + K WE E+ A + ++ +E+A +A + Sbjct: 442 ERRKLERKLREKEAAYQERLKNWEIRERKKTREYEKEAEREEERRREMAKEAKRLKEFLE 501 Query: 220 ELDDDMD------GTVSVTELQTHPELDTDGDGALSEAEAQALLSGDTQTDATSFYDRVW 273 + DDD D G+ L+ E + + D + E + L Sbjct: 502 DYDDDRDDPKYYRGSALQKRLRDR-EKEMEADERDRKREKEEL----------------- 543 Query: 274 AAIRDKYRSEALPTDLPAPSAPDLTEPKEEQPPVPSSPTEEEEEEEEEEEEEAEEE--EE 331 IR + +E P + + QP + P EEEEEE++E+EE EE EE Sbjct: 544 EEIRQRLLAEGHPDPDAELQRMEQEAERRRQPQIKQEPESEEEEEEKQEKEEKREEPMEE 603 Query: 332 EEDSEEAP------PPLSPPQPASPAEEDKMP--PYDE 361 EE+ E+ P P+S S A + P P DE Sbjct: 604 EEEPEQKPCLKPTLRPISSAPSVSSASGNATPNTPGDE 641 Score = 44.3 bits (103), Expect = 3e-04 Identities = 51/245 (20%), Positives = 100/245 (40%), Gaps = 32/245 (13%) Query: 158 KLIELQAGKKSLEDQ-VEMLRTVKEEAEKPEREAKEQHQKLWEEQLAAAKAQQEQELAAD 216 K +E + GKK E Q +E R +E + ERE +E+ ++ E+ ++E+E + Sbjct: 289 KKLEEEKGKKEKERQEIEKERRERERERERERERRERERERERER------EREKEKERE 342 Query: 217 AFKELDDDMDGTVSVTELQTHPELDTDGDGALSEAEAQALLSGDTQTDATSFYDRVWAAI 276 +E D D D T + E D D D E + + D DR Sbjct: 343 RERERDRDRDRT-KERDRDRDRERDRDRD-----RERSSDRNKDRSRSREKSRDRERERE 396 Query: 277 RDKYRSEALPTDLPAPSAPDLTEPKEEQPPVPSSPTEEEEEEEEEEEEEAEEEEEEEDSE 336 R++ R E + E+ E E E E E++++ + EE+EED+ Sbjct: 397 RERERER---------------EREREREREREREREREREREREKDKKRDREEDEEDAY 441 Query: 337 EAPPPLSPPQPASPAEEDKMPPYD----EQTQAFIDAAQEARNKFEEAERSLKDMEESIR 392 E + A ++++ ++ ++T+ + A+ + E + K ++E + Sbjct: 442 ERRKLERKLREKEAAYQERLKNWEIRERKKTREYEKEAEREEERRREMAKEAKRLKEFLE 501 Query: 393 NLEQE 397 + + + Sbjct: 502 DYDDD 506 Score = 36.6 bits (83), Expect = 0.058 Identities = 51/235 (21%), Positives = 86/235 (36%), Gaps = 19/235 (8%) Query: 173 VEMLRTVKEEAEKPEREAKEQHQKLWEEQLAAAKAQQEQELAADAFKELDDDMDGTVSVT 232 +EM ++ + + ++ H+KL EE+ K +QE E +E + + + Sbjct: 267 IEMEEDKRDLISREISKFRDTHKKLEEEKGKKEKERQEIEKER---RERERERERERERR 323 Query: 233 ELQTHPELDTDGDGALSEAEAQALLSGDTQTDATSFYDRVWAAIRDKYRSEALPTDLPAP 292 E + E + + + E E + D D T DR RD+ R +D Sbjct: 324 ERERERERERERE---KEKERERERERDRDRDRTKERDRDRDRERDRDRDRERSSDRNKD 380 Query: 293 SAPDLTEPKE-EQPPVPSSPTEEEEEEEEEEEEEAEEEEEEEDSEEAPPPLSPPQPASPA 351 + + ++ E+ E E E E E E E E E E E E + A Sbjct: 381 RSRSREKSRDREREREREREREREREREREREREREREREREREREKDKKRDREEDEEDA 440 Query: 352 EE---------DKMPPYDEQTQAFIDAAQEARNKFEEAERSLKDMEESIRNLEQE 397 E +K Y E+ + + R K E E+ + EE R + +E Sbjct: 441 YERRKLERKLREKEAAYQERLKNW---EIRERKKTREYEKEAEREEERRREMAKE 492 Score = 32.7 bits (73), Expect = 0.84 Identities = 20/77 (25%), Positives = 36/77 (46%) Query: 313 EEEEEEEEEEEEEAEEEEEEEDSEEAPPPLSPPQPASPAEEDKMPPYDEQTQAFIDAAQE 372 E +E + + E+EE EE + +E P P + Q E + P +Q + +E Sbjct: 530 EADERDRKREKEELEEIRQRLLAEGHPDPDAELQRMEQEAERRRQPQIKQEPESEEEEEE 589 Query: 373 ARNKFEEAERSLKDMEE 389 + K E+ E +++ EE Sbjct: 590 KQEKEEKREEPMEEEEE 606 >gi|118600967 shroom family member 4 [Homo sapiens] Length = 1493 Score = 53.5 bits (127), Expect = 5e-07 Identities = 30/67 (44%), Positives = 36/67 (53%), Gaps = 7/67 (10%) Query: 281 RSEALPTDLPAPSAPD-------LTEPKEEQPPVPSSPTEEEEEEEEEEEEEAEEEEEEE 333 R +A P P P + + K++Q EEEEEEEEEEEEE EEEE EE Sbjct: 1095 RKKAFPPPRPPPPNWEKYRLFRAAQQQKQQQQQQKQQEEEEEEEEEEEEEEEEEEEEAEE 1154 Query: 334 DSEEAPP 340 + EE PP Sbjct: 1155 EEEELPP 1161 Score = 37.0 bits (84), Expect = 0.045 Identities = 18/63 (28%), Positives = 33/63 (52%), Gaps = 8/63 (12%) Query: 305 PPVPSSPTEE--------EEEEEEEEEEEAEEEEEEEDSEEAPPPLSPPQPASPAEEDKM 356 PP P P E +++++++++++ +EEEEEE+ EE + A EE+ Sbjct: 1101 PPRPPPPNWEKYRLFRAAQQQKQQQQQQKQQEEEEEEEEEEEEEEEEEEEEAEEEEEELP 1160 Query: 357 PPY 359 P Y Sbjct: 1161 PQY 1163 Score = 34.3 bits (77), Expect = 0.29 Identities = 23/57 (40%), Positives = 26/57 (45%), Gaps = 8/57 (14%) Query: 301 KEEQPPVPSSPTEEEEEEEEEEEEEAEEEEEEEDSEEA--------PPPLSPPQPAS 349 +EE+ EEEEEEEEE EEE EE + S E L PQP S Sbjct: 1131 QEEEEEEEEEEEEEEEEEEEEAEEEEEELPPQYFSSETSGSCALNPEEVLEQPQPLS 1187 >gi|239745095 PREDICTED: hypothetical protein LOC645202 [Homo sapiens] Length = 570 Score = 53.5 bits (127), Expect = 5e-07 Identities = 42/255 (16%), Positives = 107/255 (41%), Gaps = 19/255 (7%) Query: 146 EDWKKAREEKQKKLIELQAGKKSLEDQVEMLRTVKEEAEKPEREAKEQHQKLWEEQLAAA 205 E W + +++++K+ + + ++++ E ++ +E+ + E + + Q + +WE++ Sbjct: 277 ELWNRLNQQQEEKMWRQE---EKIQEREEKIQEQEEKIREQEEKMRRQEEMMWEKEEKMR 333 Query: 206 KAQQEQELAADAFKELDDDMDGTVSVTELQTHPELDTDGDGALSEAEAQALLSGDTQTDA 265 + ++ + +EL++ M + E + + E + + + + + Sbjct: 334 RQEEMMWEKEEKIRELEEKMHEQEKIREQEEKRQ------------EEEKIREQEKRQEQ 381 Query: 266 TSFYDRVWAAIRDKYRSEALPTDLPAPSAPDLTEPKEEQPPVPSSPTEEEEEEEEEEEEE 325 + R IR++ ++ + E +E+ E+EE+ +EE+ Sbjct: 382 EAKMWRQEEKIREQEEKIREQEEMMQEQEEKMGEQEEKMWEQEEEMQEQEEKMRRQEEKI 441 Query: 326 AEEE----EEEEDSEEAPPPLSPPQPASPAEEDKMPPYDEQTQAFIDAAQEARNKFEEAE 381 E+E E+EE E + + +E KM + + Q + + K E E Sbjct: 442 REQEKKIREQEEKIREQEEMMQEQEEKMGEQEGKMCEQEAKMQEQEEKMRRQEEKIREQE 501 Query: 382 RSLKDMEESIRNLEQ 396 + +++ EE IR E+ Sbjct: 502 KKIREQEEKIREQEE 516 Score = 52.4 bits (124), Expect = 1e-06 Identities = 52/288 (18%), Positives = 130/288 (45%), Gaps = 13/288 (4%) Query: 117 KEKGRKERESLQQMAEVTREGFRLKKILIEDWKKAREEKQ--KKLIELQAGKKSLEDQVE 174 +EK ++ E +Q+ E +E + +KI ++ K R+E+ +K +++ ++ + ++ E Sbjct: 287 EEKMWRQEEKIQEREEKIQE--QEEKIREQEEKMRRQEEMMWEKEEKMRRQEEMMWEKEE 344 Query: 175 MLRTVKEEAEKPEREAKEQHQKLWEEQLAAAKAQQEQELAADAFKELDDDMDGTVSVTEL 234 +R ++E+ + E+ +++ ++ EE++ + +QEQE A +++ + + + E Sbjct: 345 KIRELEEKMHEQEKIREQEEKRQEEEKIREQEKRQEQE--AKMWRQEEKIREQEEKIREQ 402 Query: 235 QTHPELDTDGDGALSEAEAQALLSGDTQTDATSFYDRVWAAIRDKYRSEALPTDLPAPSA 294 + E+ + + + E E + + + R IR++ + + Sbjct: 403 E---EMMQEQEEKMGEQEEKMWEQEEEMQEQEEKMRRQEEKIREQEKKIREQEEKIREQE 459 Query: 295 PDLTEPKEEQPPVPSSPTEEE----EEEEEEEEEEAEEEEEEEDSEEAPPPLSPPQPASP 350 + E +E+ E+E E+EE+ +E + E+E+ E + + Sbjct: 460 EMMQEQEEKMGEQEGKMCEQEAKMQEQEEKMRRQEEKIREQEKKIREQEEKIREQEEMMQ 519 Query: 351 AEEDKMPPYDEQTQAFIDAAQEARNKFEEAERSLKDMEESIRNLEQEI 398 +E+KM +E+ + QE K E +++ E +R E+++ Sbjct: 520 EQEEKMWEQEEKMCEQEEKMQEQEEKMRRQEEKMREQEVRLRQQEEKM 567 Score = 49.7 bits (117), Expect = 7e-06 Identities = 57/293 (19%), Positives = 117/293 (39%), Gaps = 20/293 (6%) Query: 115 TCKEKGRKERESLQQMAEVTREGFRLKKILIEDWKKAREEKQKKLIELQAGKKSLEDQVE 174 T K+K + E L + + I E+ K+ + Q+KL +++ K ++ V+ Sbjct: 174 TQKKKADRYIEELTKERDALSLELYRNTITDEELKEKNAKLQEKLQLVESEKSEIQLNVK 233 Query: 175 MLRTVKEEAEK--PEREAKEQHQKLWEEQLAAAKAQQEQELAADAFKELDDDMDGTVSVT 232 L+ E A+ P+++ + + L +E + + Q Q + + L+ + + Sbjct: 234 ELKRKLERAKLLLPQQQLQAEADHLGKELQSVSAKLQAQVEENELWNRLNQQQEEKMWRQ 293 Query: 233 E--LQTHPELDTDGDGALSEAEAQALLSGDTQTDATSFYDRVWAAIRDKYRSEALPTDLP 290 E +Q E + + + E E + + +W R E + + Sbjct: 294 EEKIQEREEKIQEQEEKIREQEEKMRRQEEM----------MWEKEEKMRRQEEMMWE-K 342 Query: 291 APSAPDLTEPKEEQPPVPSSPTEEEEEE-----EEEEEEEAEEEEEEEDSEEAPPPLSPP 345 +L E EQ + + +EEE E+ +E+EA+ +EE E + Sbjct: 343 EEKIRELEEKMHEQEKIREQEEKRQEEEKIREQEKRQEQEAKMWRQEEKIREQEEKIREQ 402 Query: 346 QPASPAEEDKMPPYDEQTQAFIDAAQEARNKFEEAERSLKDMEESIRNLEQEI 398 + +E+KM +E+ + QE K E +++ E+ IR E++I Sbjct: 403 EEMMQEQEEKMGEQEEKMWEQEEEMQEQEEKMRRQEEKIREQEKKIREQEEKI 455 Score = 47.8 bits (112), Expect = 3e-05 Identities = 46/229 (20%), Positives = 101/229 (44%), Gaps = 9/229 (3%) Query: 118 EKGRKERESLQQMAEVTREGFRLKKILIEDWKKAREEKQKKLIELQAGKKSLEDQVEMLR 177 EK K RE ++M E + + +K E+ + +E++Q++ ++ ++ + +Q E +R Sbjct: 341 EKEEKIRELEEKMHEQEKIREQEEKRQEEEKIREQEKRQEQEAKMWRQEEKIREQEEKIR 400 Query: 178 TVKEEAEKPEREAKEQHQKLWEE----QLAAAKAQQEQELAADAFKELDDDMDGTVSVTE 233 +E ++ E + EQ +K+WE+ Q K ++++E + K++ + + E Sbjct: 401 EQEEMMQEQEEKMGEQEEKMWEQEEEMQEQEEKMRRQEEKIREQEKKIREQEEKIREQEE 460 Query: 234 L-QTHPELDTDGDGALSEAEAQALLSGDTQTDATSFYDRVWAAIRDKYRSEALPTDLPAP 292 + Q E + +G + E EA+ + IR++ ++ Sbjct: 461 MMQEQEEKMGEQEGKMCEQEAKMQEQEEKMRRQEEKIREQEKKIREQEEKIREQEEMMQE 520 Query: 293 SAPDLTEPKEEQPPVPSSPTEEEE----EEEEEEEEEAEEEEEEEDSEE 337 + E +E+ E+EE +EE+ E+E ++EE +E Sbjct: 521 QEEKMWEQEEKMCEQEEKMQEQEEKMRRQEEKMREQEVRLRQQEEKMQE 569 Database: hs.faa Posted date: Aug 4, 2009 4:42 PM Number of letters in database: 18,247,518 Number of sequences in database: 37,866 Lambda K H 0.309 0.129 0.384 Gapped Lambda K H 0.267 0.0410 0.140 Matrix: BLOSUM62 Gap Penalties: Existence: 11, Extension: 1 Number of Hits to DB: 25,730,827 Number of Sequences: 37866 Number of extensions: 1554361 Number of successful extensions: 66601 Number of sequences better than 10.0: 30 Number of HSP's better than 10.0 without gapping: 1413 Number of HSP's successfully gapped in prelim test: 1213 Number of HSP's that attempted gapping in prelim test: 18747 Number of HSP's gapped (non-prelim): 20188 length of query: 528 length of database: 18,247,518 effective HSP length: 107 effective length of query: 421 effective length of database: 14,195,856 effective search space: 5976455376 effective search space used: 5976455376 T: 11 A: 40 X1: 16 ( 7.1 bits) X2: 38 (14.6 bits) X3: 64 (24.7 bits) S1: 42 (21.7 bits) S2: 64 (29.3 bits)
Search results were obtained with NCBI BLAST and RefSeq entries.
Guide to the Human Genome
Copyright © 2010 by Stewart Scherer. All rights reserved.