Guide to the Human Genome
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Search of human proteins with 48255889

BLASTP 2.2.11 [Jun-05-2005]


Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer, 
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), 
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs",  Nucleic Acids Res. 25:3389-3402.

Query= gi|48255889 protein kinase C substrate 80K-H isoform 1 [Homo
sapiens]
         (528 letters)

Database: hs.faa 
           37,866 sequences; 18,247,518 total letters

Searching..................................................done

                                                                 Score    E
Sequences producing significant alignments:                      (bits) Value

gi|48255889 protein kinase C substrate 80K-H isoform 1 [Homo sap...  1096   0.0  
gi|48255891 protein kinase C substrate 80K-H isoform 2 [Homo sap...  1069   0.0  
gi|84043963 eukaryotic translation initiation factor 5B [Homo sa...    65   1e-10
gi|221219020 NYD-SP11 protein [Homo sapiens]                           65   2e-10
gi|16332372 cell division cycle 2-like 1 (PITSLRE proteins) isof...    64   4e-10
gi|16332362 cell division cycle 2-like 1 (PITSLRE proteins) isof...    64   4e-10
gi|148763345 cell division cycle 2-like 2 isoform 4 [Homo sapiens]     62   1e-09
gi|4505257 moesin [Homo sapiens]                                       62   1e-09
gi|16332364 cell division cycle 2-like 1 (PITSLRE proteins) isof...    62   2e-09
gi|16332358 cell division cycle 2-like 1 (PITSLRE proteins) isof...    62   2e-09
gi|239756241 PREDICTED: golgi autoantigen, golgin subfamily a-li...    61   2e-09
gi|155030232 proline, glutamic acid and leucine rich protein 1 [...    61   2e-09
gi|222418637 golgi autoantigen, golgin subfamily a-like [Homo sa...    61   3e-09
gi|148763347 cell division cycle 2-like 2 isoform 1 [Homo sapiens]     59   8e-09
gi|16332370 cell division cycle 2-like 1 (PITSLRE proteins) isof...    59   1e-08
gi|239745089 PREDICTED: golgi autoantigen, golgin subfamily a-li...    58   2e-08
gi|17975763 myelin transcription factor 1 [Homo sapiens]               57   3e-08
gi|100816397 MYST histone acetyltransferase (monocytic leukemia)...    57   3e-08
gi|117414137 retinitis pigmentosa 1-like 1 [Homo sapiens]              57   3e-08
gi|14249738 N-acetylglucosamine-1-phosphotransferase, gamma subu...    57   5e-08
gi|154759293 cysteine-rich hydrophobic domain 1 [Homo sapiens]         57   5e-08
gi|239745079 PREDICTED: Putative golgin subfamily A member 6-lik...    55   1e-07
gi|148746195 trichohyalin [Homo sapiens]                               55   1e-07
gi|24307879 dynein, cytoplasmic 1, intermediate chain 2 [Homo sa...    55   1e-07
gi|222446603 golgi autoantigen, golgin subfamily a-like [Homo sa...    55   2e-07
gi|157738649 neurofilament, medium polypeptide 150kDa isoform 1 ...    55   2e-07
gi|157738641 neurofilament, medium polypeptide 150kDa isoform 2 ...    55   2e-07
gi|55741709 RNA binding motif protein 25 [Homo sapiens]                54   3e-07
gi|118600967 shroom family member 4 [Homo sapiens]                     54   5e-07
gi|239745095 PREDICTED: hypothetical protein LOC645202 [Homo sap...    54   5e-07

>gi|48255889 protein kinase C substrate 80K-H isoform 1 [Homo
           sapiens]
          Length = 528

 Score = 1096 bits (2834), Expect = 0.0
 Identities = 528/528 (100%), Positives = 528/528 (100%)

Query: 1   MLLPLLLLLPMCWAVEVKRPRGVSLTNHHFYDESKPFTCLDGSATIPFDQVNDDYCDCKD 60
           MLLPLLLLLPMCWAVEVKRPRGVSLTNHHFYDESKPFTCLDGSATIPFDQVNDDYCDCKD
Sbjct: 1   MLLPLLLLLPMCWAVEVKRPRGVSLTNHHFYDESKPFTCLDGSATIPFDQVNDDYCDCKD 60

Query: 61  GSDEPGTAACPNGSFHCTNTGYKPLYIPSNRVNDGVCDCCDGTDEYNSGVICENTCKEKG 120
           GSDEPGTAACPNGSFHCTNTGYKPLYIPSNRVNDGVCDCCDGTDEYNSGVICENTCKEKG
Sbjct: 61  GSDEPGTAACPNGSFHCTNTGYKPLYIPSNRVNDGVCDCCDGTDEYNSGVICENTCKEKG 120

Query: 121 RKERESLQQMAEVTREGFRLKKILIEDWKKAREEKQKKLIELQAGKKSLEDQVEMLRTVK 180
           RKERESLQQMAEVTREGFRLKKILIEDWKKAREEKQKKLIELQAGKKSLEDQVEMLRTVK
Sbjct: 121 RKERESLQQMAEVTREGFRLKKILIEDWKKAREEKQKKLIELQAGKKSLEDQVEMLRTVK 180

Query: 181 EEAEKPEREAKEQHQKLWEEQLAAAKAQQEQELAADAFKELDDDMDGTVSVTELQTHPEL 240
           EEAEKPEREAKEQHQKLWEEQLAAAKAQQEQELAADAFKELDDDMDGTVSVTELQTHPEL
Sbjct: 181 EEAEKPEREAKEQHQKLWEEQLAAAKAQQEQELAADAFKELDDDMDGTVSVTELQTHPEL 240

Query: 241 DTDGDGALSEAEAQALLSGDTQTDATSFYDRVWAAIRDKYRSEALPTDLPAPSAPDLTEP 300
           DTDGDGALSEAEAQALLSGDTQTDATSFYDRVWAAIRDKYRSEALPTDLPAPSAPDLTEP
Sbjct: 241 DTDGDGALSEAEAQALLSGDTQTDATSFYDRVWAAIRDKYRSEALPTDLPAPSAPDLTEP 300

Query: 301 KEEQPPVPSSPTEEEEEEEEEEEEEAEEEEEEEDSEEAPPPLSPPQPASPAEEDKMPPYD 360
           KEEQPPVPSSPTEEEEEEEEEEEEEAEEEEEEEDSEEAPPPLSPPQPASPAEEDKMPPYD
Sbjct: 301 KEEQPPVPSSPTEEEEEEEEEEEEEAEEEEEEEDSEEAPPPLSPPQPASPAEEDKMPPYD 360

Query: 361 EQTQAFIDAAQEARNKFEEAERSLKDMEESIRNLEQEISFDFGPNGEFAYLYSQCYELTT 420
           EQTQAFIDAAQEARNKFEEAERSLKDMEESIRNLEQEISFDFGPNGEFAYLYSQCYELTT
Sbjct: 361 EQTQAFIDAAQEARNKFEEAERSLKDMEESIRNLEQEISFDFGPNGEFAYLYSQCYELTT 420

Query: 421 NEYVYRLCPFKLVSQKPKLGGSPTSLGTWGSWIGPDHDKFSAMKYEQGTGCWQGPNRSTT 480
           NEYVYRLCPFKLVSQKPKLGGSPTSLGTWGSWIGPDHDKFSAMKYEQGTGCWQGPNRSTT
Sbjct: 421 NEYVYRLCPFKLVSQKPKLGGSPTSLGTWGSWIGPDHDKFSAMKYEQGTGCWQGPNRSTT 480

Query: 481 VRLLCGKETMVTSTTEPSRCEYLMELMTPAACPEPPPEAPTEDDHDEL 528
           VRLLCGKETMVTSTTEPSRCEYLMELMTPAACPEPPPEAPTEDDHDEL
Sbjct: 481 VRLLCGKETMVTSTTEPSRCEYLMELMTPAACPEPPPEAPTEDDHDEL 528


>gi|48255891 protein kinase C substrate 80K-H isoform 2 [Homo
           sapiens]
          Length = 525

 Score = 1069 bits (2765), Expect = 0.0
 Identities = 519/528 (98%), Positives = 520/528 (98%), Gaps = 3/528 (0%)

Query: 1   MLLPLLLLLPMCWAVEVKRPRGVSLTNHHFYDESKPFTCLDGSATIPFDQVNDDYCDCKD 60
           MLLPLLLLLPMCWAVEVKRPRGVSLTNHHFYDESKPFTCLDGSATIPFDQVNDDYCDCKD
Sbjct: 1   MLLPLLLLLPMCWAVEVKRPRGVSLTNHHFYDESKPFTCLDGSATIPFDQVNDDYCDCKD 60

Query: 61  GSDEPGTAACPNGSFHCTNTGYKPLYIPSNRVNDGVCDCCDGTDEYNSGVICENTCKEKG 120
           GSDEPGTAACPNGSFHCTNTGYKPLYIPSNRVNDGVCDCCDGTDEYNSGVICENTCKEKG
Sbjct: 61  GSDEPGTAACPNGSFHCTNTGYKPLYIPSNRVNDGVCDCCDGTDEYNSGVICENTCKEKG 120

Query: 121 RKERESLQQMAEVTREGFRLKKILIEDWKKAREEKQKKLIELQAGKKSLEDQVEMLRTVK 180
           RKERESLQQMAEVTREGFRLKKILIEDWKKAREEKQKKLIELQAGKKSLEDQVEMLRTVK
Sbjct: 121 RKERESLQQMAEVTREGFRLKKILIEDWKKAREEKQKKLIELQAGKKSLEDQVEMLRTVK 180

Query: 181 EEAEKPEREAKEQHQKLWEEQLAAAKAQQEQELAADAFKELDDDMDGTVSVTELQTHPEL 240
           EEAEKPEREAKEQHQKLWEEQLAAAKAQQEQELAADAFKELDDDMDGTVSVTELQTHPEL
Sbjct: 181 EEAEKPEREAKEQHQKLWEEQLAAAKAQQEQELAADAFKELDDDMDGTVSVTELQTHPEL 240

Query: 241 DTDGDGALSEAEAQALLSGDTQTDATSFYDRVWAAIRDKYRSEALPTDLPAPSAPDLTEP 300
           DTDGDGALSEAEAQALLSGDTQTDATSFYDRVWAAIRDKYRSEALPTDLPAPSAPDLTEP
Sbjct: 241 DTDGDGALSEAEAQALLSGDTQTDATSFYDRVWAAIRDKYRSEALPTDLPAPSAPDLTEP 300

Query: 301 KEEQPPVPSSPTEEEEEEEEEEEEEAEEEEEEEDSEEAPPPLSPPQPASPAEEDKMPPYD 360
           KEEQPPVPSSPTEEEEEEEEEEEEEAEEEEEEEDSE        P+PASPAEEDKMPPYD
Sbjct: 301 KEEQPPVPSSPTEEEEEEEEEEEEEAEEEEEEEDSEVQG---EQPKPASPAEEDKMPPYD 357

Query: 361 EQTQAFIDAAQEARNKFEEAERSLKDMEESIRNLEQEISFDFGPNGEFAYLYSQCYELTT 420
           EQTQAFIDAAQEARNKFEEAERSLKDMEESIRNLEQEISFDFGPNGEFAYLYSQCYELTT
Sbjct: 358 EQTQAFIDAAQEARNKFEEAERSLKDMEESIRNLEQEISFDFGPNGEFAYLYSQCYELTT 417

Query: 421 NEYVYRLCPFKLVSQKPKLGGSPTSLGTWGSWIGPDHDKFSAMKYEQGTGCWQGPNRSTT 480
           NEYVYRLCPFKLVSQKPKLGGSPTSLGTWGSWIGPDHDKFSAMKYEQGTGCWQGPNRSTT
Sbjct: 418 NEYVYRLCPFKLVSQKPKLGGSPTSLGTWGSWIGPDHDKFSAMKYEQGTGCWQGPNRSTT 477

Query: 481 VRLLCGKETMVTSTTEPSRCEYLMELMTPAACPEPPPEAPTEDDHDEL 528
           VRLLCGKETMVTSTTEPSRCEYLMELMTPAACPEPPPEAPTEDDHDEL
Sbjct: 478 VRLLCGKETMVTSTTEPSRCEYLMELMTPAACPEPPPEAPTEDDHDEL 525


>gi|84043963 eukaryotic translation initiation factor 5B [Homo
           sapiens]
          Length = 1220

 Score = 65.5 bits (158), Expect = 1e-10
 Identities = 65/246 (26%), Positives = 111/246 (45%), Gaps = 40/246 (16%)

Query: 118 EKGRKERESLQQMAEVTREGFR--LKKILIEDWKKAREEKQ--KKLIELQAGKKSLEDQV 173
           EK  KE+E  +  ++ T +  +  L K+  E+ ++ REE++  K+L EL+A +K  E   
Sbjct: 324 EKEEKEKEKKKGPSKATVKAMQEALAKLKEEEERQKREEEERIKRLEELEAKRKEEE--- 380

Query: 174 EMLRTVKEEAEKPEREAKEQHQKLWEEQLAAAKAQQEQELAADAFKELDDDMDGTVSVTE 233
              R  +E+ E+ +++ KE+ ++L +E     K+Q+E    A+A  +L       V V  
Sbjct: 381 ---RLEQEKRERKKQKEKERKERLKKEGKLLTKSQREARARAEATLKLLQAQG--VEVPS 435

Query: 234 LQTHPELDTDGDGALSEAEAQALLSGDTQTDATSFYDRVWAAIRDKYRSEALPTDLPAPS 293
             + P+        + E + +  +    ++   S    + AA+    +      + P P 
Sbjct: 436 KDSLPK-----KRPIYEDKKRKKIPQQLESKEVSESMELCAAVEVMEQGVPEKEETPPPV 490

Query: 294 APDLTEPKEE-----------------------QPPVPSSPTEEEEEEEEEEEEEAEEEE 330
            P+  E  E+                          V  +P EEEEEEEEEEE+E  EEE
Sbjct: 491 EPEEEEDTEDAGLDDWEAMASDEETEKVEGNKVHIEVKENPEEEEEEEEEEEEDEESEEE 550

Query: 331 EEEDSE 336
           EEE+ E
Sbjct: 551 EEEEGE 556



 Score = 63.2 bits (152), Expect = 6e-10
 Identities = 68/305 (22%), Positives = 141/305 (46%), Gaps = 25/305 (8%)

Query: 122 KERESLQQMAEVTREGFRLKKILIEDWKKAREEKQKKLIELQAG--KKSLEDQVEMLRTV 179
           +E+      AE   EG + KK    D KK + EK++K  E + G  K +++   E L  +
Sbjct: 296 EEKAETPTAAEDDNEGDKKKK----DKKKKKGEKEEKEKEKKKGPSKATVKAMQEALAKL 351

Query: 180 KEEAEKPEREAKEQHQKLWEEQLAAAKAQQEQ------ELAADAFKELDDDM--DGTVSV 231
           KEE E+ +RE +E+ ++L  E+L A + ++E+      E      KE  + +  +G + +
Sbjct: 352 KEEEERQKREEEERIKRL--EELEAKRKEEERLEQEKRERKKQKEKERKERLKKEGKL-L 408

Query: 232 TELQTHPELDTDGDGALSEAEAQALLSGDTQTDATSFY-DRVWAAIRDKYRSEALPTDLP 290
           T+ Q       +    L +A+   + S D+       Y D+    I  +  S+ +   + 
Sbjct: 409 TKSQREARARAEATLKLLQAQGVEVPSKDSLPKKRPIYEDKKRKKIPQQLESKEVSESME 468

Query: 291 APSAPDLTE---PKEEQPPVPSSPTEEEEEEE----EEEEEEAEEEEEEEDSEEAPPPLS 343
             +A ++ E   P++E+ P P  P EEE+ E+    + E   ++EE E+ +  +    + 
Sbjct: 469 LCAAVEVMEQGVPEKEETPPPVEPEEEEDTEDAGLDDWEAMASDEETEKVEGNKVHIEVK 528

Query: 344 PPQPASPAEEDKMPPYDEQTQAFIDAAQEARNKFEEAERSLKDMEESIRNLEQEISFDFG 403
                   EE++    +E  +   +  +   ++ +E +  + D ++S + L+++ S +  
Sbjct: 529 ENPEEEEEEEEEEEEDEESEEEEEEEGESEGSEGDEEDEKVSDEKDSGKTLDKKPSKEMS 588

Query: 404 PNGEF 408
            + E+
Sbjct: 589 SDSEY 593



 Score = 44.3 bits (103), Expect = 3e-04
 Identities = 55/262 (20%), Positives = 103/262 (39%), Gaps = 16/262 (6%)

Query: 145 IEDWKKAREEKQKKLIELQAGKKSLEDQVEMLRTVKEEAEKPEREAKEQHQKLWEEQLAA 204
           +ED     ++  K  +E+ +G    +D  ++ +  K +A+K  ++     +   E+    
Sbjct: 116 LEDKDSKSKKTAKPKVEMYSGSDDDDDFNKLPKKAKGKAQKSNKKWDGSEED--EDNSKK 173

Query: 205 AKAQQEQELAADAFKELDDDMDGTVSVTELQTHP-----ELDTDGDGALSEAEAQALLSG 259
            K +     + ++  E D+ +       + Q +      E   + D A  + +  A    
Sbjct: 174 IKERSRINSSGESGDESDEFLQSRKGQKKNQKNKPGPNIESGNEDDDASFKIKTVAQKKA 233

Query: 260 DTQTDATSFYDRVWAAIRDKYRSEALPTDLPAPSAPDLTEPKEEQPPVPSSPTEEE---- 315
           + +       D   A +R     E L T     S    ++ K E+  V S  T +     
Sbjct: 234 EKKERERKKRDEEKAKLRKLKEKEELETGKKDQSKQKESQRKFEEETVKSKVTVDTGVIP 293

Query: 316 EEEEEEEEEEAEEEEEEEDSEEAPPPLSPPQPASPAEEDKMPPYDEQTQAFIDAAQEARN 375
             EE+ E   A E++ E D ++        +     +E K  P    ++A + A QEA  
Sbjct: 294 ASEEKAETPTAAEDDNEGDKKKKDKKKKKGEKEEKEKEKKKGP----SKATVKAMQEALA 349

Query: 376 KF-EEAERSLKDMEESIRNLEQ 396
           K  EE ER  ++ EE I+ LE+
Sbjct: 350 KLKEEEERQKREEEERIKRLEE 371


>gi|221219020 NYD-SP11 protein [Homo sapiens]
          Length = 2873

 Score = 65.1 bits (157), Expect = 2e-10
 Identities = 73/298 (24%), Positives = 136/298 (45%), Gaps = 37/298 (12%)

Query: 117  KEKGRKERESLQQMAEVTREGFRLKKILIEDWKKAREEKQ--KKLIELQAGKKSLEDQVE 174
            ++  +  R+ +++   +++E  +L KIL    K  R+E++  ++ I++   K++L  +  
Sbjct: 2050 RKLAKASRKLIKKRESLSKEPAKLNKILKALQKLTRDERKLTQEEIKMTKMKRALFVKER 2109

Query: 175  MLRTVKEEAEKPEREAKEQHQKLWEEQLAAAKAQQEQELAADAFKELDDDMDGTVSVTEL 234
             L   + + +  E +  E+  +L +++   A+ Q++  LA    + ++ +   T   ++L
Sbjct: 2110 RLSIEQSKLDIKEWDFSEKRSELTKDEKKLARKQRK--LANKMRRMINKEEKMTEEESKL 2167

Query: 235  -QTHPE--LDTDGDGALSEAEAQALLS-----------GDTQTDATSFYDRVWAAIRDKY 280
             + H E  LD + +G + E E    L            GD   +   F  +V     +++
Sbjct: 2168 ARKHSEVILDDEEEGGIEEEEVIPFLKRRWRKRKEAKRGDKPKE--KFSSQVDEVESEEH 2225

Query: 281  RSEALPTDLPAPSAPDLTEPKEEQPPVPSSPTEEEEEEEEEEEEEAEEEEEEEDSEEAPP 340
             SE + +         L +  E+Q  + S   EE EEEEE EEEE  EEEEE   EE   
Sbjct: 2226 FSEEMES---------LLDELEKQESLSSEEEEEREEEEEREEEEVREEEEERKEEEE-- 2274

Query: 341  PLSPPQPASPAEEDKMPPYDEQTQAFIDAAQEARNKFEEAERSLKDME-ESIRNLEQE 397
                 +     EE+K     E+ +   +  QE    FEE E  + + E ES+ + E+E
Sbjct: 2275 --GEEKQVEKEEEEKKKKKKEKKK---EEVQEKEEVFEEKEEIMSEEETESLSDEEEE 2327



 Score = 46.2 bits (108), Expect = 7e-05
 Identities = 63/288 (21%), Positives = 114/288 (39%), Gaps = 41/288 (14%)

Query: 117  KEKGRKERESLQQMAEVTREGFRLKKILIEDWKKAREEKQKKLIELQAGKKSLEDQVEML 176
            KE+  K+ E +    EV+REG               EEK++++ E Q   + ++++ +  
Sbjct: 1534 KEQQYKDEEEVTLEEEVSREG---------------EEKEQQVTEEQ---RHIQEEHKWA 1575

Query: 177  RTVKEEAEKPEREAKEQHQKLWEEQLAAAK----AQQEQELAADAFKELDDDMDGTVSVT 232
            R  ++ A   ++ A+E+ +   EE+  A +    AQ+E++LA    K   DD +      
Sbjct: 1576 RIHRKRARAEKKRAQEERKLAQEEEKLAQEERQLAQEERKLAQAYVKITQDDRE------ 1629

Query: 233  ELQTHPELDTDGDGALSEAEAQALLSGDTQTDATSFYDRVWAAIRDKYRSEALPTDLPAP 292
                        +G  ++ E      G+  +       +    +  K+   A   +  A 
Sbjct: 1630 --------MAQAEGKFAQKEETLAQRGEKLSQEAEKLAQKRKKLAKKWEKVAREEEKLAK 1681

Query: 293  SAPDLTEPKE-EQPPVPSSPTEEEEEEEEEEEEEAEEEEEEEDSEEAPPPLSPPQPASPA 351
                L E K      V   P  E+  + +E+E   E EE E D EE    LS  +     
Sbjct: 1682 KGGKLAEVKNILAQKVEELPQREQNLDWQEKELAQELEELEWDMEE----LSWKEEELNQ 1737

Query: 352  EEDKMPPYDEQTQAFIDAAQEARNKFEEAERSLKDMEESIRNLEQEIS 399
            EE K+    ++     +A    R K  E E  L   EE +   +++++
Sbjct: 1738 EEGKLVEEKKKLAEEEEALAWQREKLSEEETKLAQEEELLIQEKEKLA 1785



 Score = 38.9 bits (89), Expect = 0.012
 Identities = 62/299 (20%), Positives = 115/299 (38%), Gaps = 52/299 (17%)

Query: 133  VTREGFRLKKILIED----WKKARE-----------EKQKKLIELQAGKKSLEDQVEMLR 177
            VT+E  R K+++  +     KKAR+           +K KK+I L+ G  ++  ++    
Sbjct: 1332 VTQEVIRHKEVMPREEEQAQKKARDMLGLEETQVILKKGKKVIFLEPGNVTMGKEIS--- 1388

Query: 178  TVKEEAEKPEREAKEQHQKLWEEQLAAAKAQQEQELAADAFKELDDDMDGTVSVTELQTH 237
              K+E +K  +++ +Q +K  +++    K ++E            ++ D +  V E+ T 
Sbjct: 1389 --KKEEKKTFQKSPKQGRKAVQKERKVGKIKREMT---------KEERDMSEEVEEMATL 1437

Query: 238  PELDTDGDGALSEAEAQALLSG-----DTQTDATSFYDRVWAAIRDKYRSEALPTDLPAP 292
             E     +G L   E            D          + W A ++++    L  +    
Sbjct: 1438 EEKVVKQEGKLVMIERTPSWQDWKKAWDEWKQVHGETRKSWKAWKEEWEKRLLQEEEKLH 1497

Query: 293  SAPDLTEPKEEQPPVPSSPTEEE--------------EEEEEEEEEEAEEEEEEEDSEEA 338
             A +   P+EE          EE              E++ ++EEE   EEE   + EE 
Sbjct: 1498 QAGEKLSPEEEMLQEDKKLKWEEWKQVWENMLSSKSKEQQYKDEEEVTLEEEVSREGEEK 1557

Query: 339  PPPLSPPQPASPAEEDKMPPYDEQTQAFIDAAQEARNKFEEAERSLKDMEESIRNLEQE 397
               ++  Q     E      + ++ +A    AQE R   +E E+    + +  R L QE
Sbjct: 1558 EQQVTEEQRHIQEEHKWARIHRKRARAEKKRAQEERKLAQEEEK----LAQEERQLAQE 1612



 Score = 38.1 bits (87), Expect = 0.020
 Identities = 65/318 (20%), Positives = 117/318 (36%), Gaps = 48/318 (15%)

Query: 117  KEKGRKERESLQQMAEVTREGFRLKKILIEDWKKAREEKQKKLIELQAGKKSLEDQVEML 176
            +EK  +  E L    E+ +E    KK+  E+WK+  E       + Q  K   E++V + 
Sbjct: 1493 EEKLHQAGEKLSPEEEMLQED---KKLKWEEWKQVWENMLSSKSKEQQYKD--EEEVTLE 1547

Query: 177  RTVKEEAEKPEREAKEQHQKLWEEQLAAA-----------KAQQEQELAADAFKELDDDM 225
              V  E E+ E++  E+ + + EE   A            +AQ+E++LA +  K   ++ 
Sbjct: 1548 EEVSREGEEKEQQVTEEQRHIQEEHKWARIHRKRARAEKKRAQEERKLAQEEEKLAQEER 1607

Query: 226  DGTVSVTEL-QTHPELDTD------GDGALSEAEAQALLSGDTQTDATSFYDRVWAAIRD 278
                   +L Q + ++  D       +G  ++ E      G+  +       +    +  
Sbjct: 1608 QLAQEERKLAQAYVKITQDDREMAQAEGKFAQKEETLAQRGEKLSQEAEKLAQKRKKLAK 1667

Query: 279  KYRSEALPTDLPAPSAPDLTEPK-------EEQPPVPSSPTEEEEE-------------- 317
            K+   A   +  A     L E K       EE P    +   +E+E              
Sbjct: 1668 KWEKVAREEEKLAKKGGKLAEVKNILAQKVEELPQREQNLDWQEKELAQELEELEWDMEE 1727

Query: 318  ----EEEEEEEEAEEEEEEEDSEEAPPPLSPPQPASPAEEDKMPPYDEQTQAFIDAAQEA 373
                EEE  +EE +  EE++   E    L+  +     EE K+   +E      +   + 
Sbjct: 1728 LSWKEEELNQEEGKLVEEKKKLAEEEEALAWQREKLSEEETKLAQEEELLIQEKEKLAQH 1787

Query: 374  RNKFEEAERSLKDMEESI 391
            + K  E E  L    E +
Sbjct: 1788 KEKMPEEEERLGRKREQL 1805



 Score = 32.0 bits (71), Expect = 1.4
 Identities = 70/323 (21%), Positives = 126/323 (39%), Gaps = 64/323 (19%)

Query: 117  KEKGRKERESLQQMAE--------VTREGFRLKKILIE------DWKKAREEKQKKLIEL 162
            +E  ++ER+  +++ E        V +EG   K ++IE      DWKKA +E ++   E 
Sbjct: 1418 REMTKEERDMSEEVEEMATLEEKVVKQEG---KLVMIERTPSWQDWKKAWDEWKQVHGET 1474

Query: 163  QAGKKSLEDQVEMLRTVKEE-----AEK--PEREAKEQHQKL-WEEQLAAAKAQQEQELA 214
            +   K+ +++ E     +EE      EK  PE E  ++ +KL WEE     K   E  L+
Sbjct: 1475 RKSWKAWKEEWEKRLLQEEEKLHQAGEKLSPEEEMLQEDKKLKWEEW----KQVWENMLS 1530

Query: 215  ADAFKELDDDMDGTVSVTELQTHPELDTDGDGALSEAEAQALLSGDTQTDATSFYDRVWA 274
            + + ++   D +      E+    E+  +G+    E E Q      T+       +  WA
Sbjct: 1531 SKSKEQQYKDEE------EVTLEEEVSREGE----EKEQQV-----TEEQRHIQEEHKWA 1575

Query: 275  AIRDKYRSEALPTDLPAPSAPDLTEPKEEQPPVPSSPTEEEEEEEEEEEEEAEEEEEEED 334
             I  K R+ A              E K  Q        +  +EEE+  +EE +  +EE  
Sbjct: 1576 RIHRK-RARA--------------EKKRAQ-----EERKLAQEEEKLAQEERQLAQEERK 1615

Query: 335  SEEAPPPLSPPQPASPAEEDKMPPYDEQTQAFIDAAQEARNKFEEAERSLKDMEESIRNL 394
              +A   ++         E K    +E      +   +   K  +  + L    E +   
Sbjct: 1616 LAQAYVKITQDDREMAQAEGKFAQKEETLAQRGEKLSQEAEKLAQKRKKLAKKWEKVARE 1675

Query: 395  EQEISFDFGPNGEFAYLYSQCYE 417
            E++++   G   E   + +Q  E
Sbjct: 1676 EEKLAKKGGKLAEVKNILAQKVE 1698



 Score = 30.0 bits (66), Expect = 5.4
 Identities = 21/102 (20%), Positives = 54/102 (52%)

Query: 113  ENTCKEKGRKERESLQQMAEVTREGFRLKKILIEDWKKAREEKQKKLIELQAGKKSLEDQ 172
            E   +E+  +E++  ++  E  ++    KK  +++ ++  EEK++ + E +    S E++
Sbjct: 2267 EERKEEEEGEEKQVEKEEEEKKKKKKEKKKEEVQEKEEVFEEKEEIMSEEETESLSDEEE 2326

Query: 173  VEMLRTVKEEAEKPEREAKEQHQKLWEEQLAAAKAQQEQELA 214
             E   +++EE ++ +   K++ Q   +EQ   +   +E+ L+
Sbjct: 2327 EEESCSLEEEVDREKEILKKEKQFKLQEQRRKSLRGRERVLS 2368


>gi|16332372 cell division cycle 2-like 1 (PITSLRE proteins) isoform
           9 [Homo sapiens]
          Length = 771

 Score = 63.5 bits (153), Expect = 4e-10
 Identities = 73/284 (25%), Positives = 119/284 (41%), Gaps = 26/284 (9%)

Query: 117 KEKGRKERESLQQMAEVTREGFRLKKILIEDWKKARE-EKQKKLIELQAGKKSLEDQVEM 175
           K++ RKE++  + + E  RE  R K+   E  K  RE E+QK+    +   +   D++E 
Sbjct: 101 KDEKRKEKKHAR-VKEKEREHERRKRHREEQDKARREWERQKRREMAREHSRRERDRLEQ 159

Query: 176 LRTVKEEAEKPEREAKEQHQKLWEEQLAAAKAQQEQ---ELAADAFKELDDDMDGTVSVT 232
           L   +E   K   + KEQ ++   E+ A  + ++ +   E++A   + + +D    V  +
Sbjct: 160 LERKRERERKMREQQKEQREQKERERRAEERRKEREARREVSAH-HRTMREDYSDKVKAS 218

Query: 233 ELQTHP-----ELDTDGDGALSEAEAQALLSGDTQTDATSFYDRVWAAIRDKYRSEALPT 287
                P     E    GDG     E + +   D  +D           I D  R  +   
Sbjct: 219 HWSRSPPRPPRERFELGDGRKPVKE-EKMEERDLLSDLQD--------ISDSERKTSSAE 269

Query: 288 DLPAPSAPDLTEPKEEQPPVPSSPTEEEEEEEEEEEEEAEEEEEEEDSEEAPPPLSPPQP 347
              A S     E +EE+       +  EE EEEEEEEE EEEE   +SEEA       Q 
Sbjct: 270 SSSAESGSGSEEEEEEEEEEEEEGSTSEESEEEEEEEEEEEEETGSNSEEA-----SEQS 324

Query: 348 ASPAEEDKMPPYDEQTQAFIDAAQEARNKFEEAERSLKDMEESI 391
           A    E++M   DE+ +          ++F+      ++ EE +
Sbjct: 325 AEEVSEEEMSE-DEERENENHLLVVPESRFDRDSGESEEAEEEV 367



 Score = 48.9 bits (115), Expect = 1e-05
 Identities = 67/315 (21%), Positives = 122/315 (38%), Gaps = 25/315 (7%)

Query: 149 KKAREEKQKKLIELQAGKKSLEDQVEMLRTVKEEAEKPEREAKEQHQ--KLWEEQLAAAK 206
           K  ++  +K+ +  +  +K  E +   ++  + E E+ +R  +EQ +  + WE Q     
Sbjct: 86  KPPQQMSRKEKVHHRKDEKRKEKKHARVKEKEREHERRKRHREEQDKARREWERQKRREM 145

Query: 207 AQQEQELAADAFKELDDDMDGTVSVTELQTHP----ELDTDGDGALSEAEAQALLSGDTQ 262
           A++      D  ++L+   +    + E Q       E +   +    E EA+  +S   +
Sbjct: 146 AREHSRRERDRLEQLERKRERERKMREQQKEQREQKERERRAEERRKEREARREVSAHHR 205

Query: 263 TDATSFYDRVWAA--IRDKYRSEALPTDLPAPSAPDLTEPKEEQP------PVPSSPTEE 314
           T    + D+V A+   R   R      +L     P   E  EE+        +  S  + 
Sbjct: 206 TMREDYSDKVKASHWSRSPPRPPRERFELGDGRKPVKEEKMEERDLLSDLQDISDSERKT 265

Query: 315 EEEEEEEEEEEAEEEEEEEDSEEAPPPLSPPQPASPAEEDKMPPYDEQTQAFIDAAQEAR 374
              E    E  +  EEEEE+ EE     S  + +   EE++    +E      +A++++ 
Sbjct: 266 SSAESSSAESGSGSEEEEEEEEEEEEEGSTSEESEEEEEEEEEEEEETGSNSEEASEQSA 325

Query: 375 NKFEEAERSLKDMEESIRNL----EQEISFDFGPNGEFAYLYS----QCYELTTNEYV-- 424
            +  E E S  +  E+  +L    E     D G + E          Q   LT  +YV  
Sbjct: 326 EEVSEEEMSEDEERENENHLLVVPESRFDRDSGESEEAEEEVGEGTPQSSALTEGDYVPD 385

Query: 425 -YRLCPFKLVSQKPK 438
              L P +L  + PK
Sbjct: 386 SPALSPIELKQELPK 400



 Score = 30.0 bits (66), Expect = 5.4
 Identities = 31/144 (21%), Positives = 53/144 (36%), Gaps = 6/144 (4%)

Query: 51  VNDDYCDCKDGSDEPGTAACPNGSFHCTNTGYKPLYIPSNRVNDGVCDCCDGTDEYNSGV 110
           + +DY D    S    +   P         G KP+        D + D  D +D      
Sbjct: 207 MREDYSDKVKASHWSRSPPRPPRERFELGDGRKPVKEEKMEERDLLSDLQDISDSERKTS 266

Query: 111 ICENTCKEKGRKERESLQQMAEVTREGFRLKKILIEDWKKAREEKQKKLIELQAGKKSLE 170
             E++  E G    E  ++  E   EG   ++   E+ ++  EE++      +A ++S E
Sbjct: 267 SAESSSAESGSGSEEEEEEEEEEEEEGSTSEESEEEEEEEEEEEEETGSNSEEASEQSAE 326

Query: 171 DQVEMLRTVKEEAEKPEREAKEQH 194
           +  E      EE  + E    E H
Sbjct: 327 EVSE------EEMSEDEERENENH 344


>gi|16332362 cell division cycle 2-like 1 (PITSLRE proteins) isoform
           4 [Homo sapiens]
          Length = 737

 Score = 63.5 bits (153), Expect = 4e-10
 Identities = 73/284 (25%), Positives = 119/284 (41%), Gaps = 26/284 (9%)

Query: 117 KEKGRKERESLQQMAEVTREGFRLKKILIEDWKKARE-EKQKKLIELQAGKKSLEDQVEM 175
           K++ RKE++  + + E  RE  R K+   E  K  RE E+QK+    +   +   D++E 
Sbjct: 67  KDEKRKEKKHAR-VKEKEREHERRKRHREEQDKARREWERQKRREMAREHSRRERDRLEQ 125

Query: 176 LRTVKEEAEKPEREAKEQHQKLWEEQLAAAKAQQEQ---ELAADAFKELDDDMDGTVSVT 232
           L   +E   K   + KEQ ++   E+ A  + ++ +   E++A   + + +D    V  +
Sbjct: 126 LERKRERERKMREQQKEQREQKERERRAEERRKEREARREVSAH-HRTMREDYSDKVKAS 184

Query: 233 ELQTHP-----ELDTDGDGALSEAEAQALLSGDTQTDATSFYDRVWAAIRDKYRSEALPT 287
                P     E    GDG     E + +   D  +D           I D  R  +   
Sbjct: 185 HWSRSPPRPPRERFELGDGRKPVKE-EKMEERDLLSDLQD--------ISDSERKTSSAE 235

Query: 288 DLPAPSAPDLTEPKEEQPPVPSSPTEEEEEEEEEEEEEAEEEEEEEDSEEAPPPLSPPQP 347
              A S     E +EE+       +  EE EEEEEEEE EEEE   +SEEA       Q 
Sbjct: 236 SSSAESGSGSEEEEEEEEEEEEEGSTSEESEEEEEEEEEEEEETGSNSEEA-----SEQS 290

Query: 348 ASPAEEDKMPPYDEQTQAFIDAAQEARNKFEEAERSLKDMEESI 391
           A    E++M   DE+ +          ++F+      ++ EE +
Sbjct: 291 AEEVSEEEMSE-DEERENENHLLVVPESRFDRDSGESEEAEEEV 333



 Score = 48.9 bits (115), Expect = 1e-05
 Identities = 67/315 (21%), Positives = 122/315 (38%), Gaps = 25/315 (7%)

Query: 149 KKAREEKQKKLIELQAGKKSLEDQVEMLRTVKEEAEKPEREAKEQHQ--KLWEEQLAAAK 206
           K  ++  +K+ +  +  +K  E +   ++  + E E+ +R  +EQ +  + WE Q     
Sbjct: 52  KPPQQMSRKEKVHHRKDEKRKEKKHARVKEKEREHERRKRHREEQDKARREWERQKRREM 111

Query: 207 AQQEQELAADAFKELDDDMDGTVSVTELQTHP----ELDTDGDGALSEAEAQALLSGDTQ 262
           A++      D  ++L+   +    + E Q       E +   +    E EA+  +S   +
Sbjct: 112 AREHSRRERDRLEQLERKRERERKMREQQKEQREQKERERRAEERRKEREARREVSAHHR 171

Query: 263 TDATSFYDRVWAA--IRDKYRSEALPTDLPAPSAPDLTEPKEEQP------PVPSSPTEE 314
           T    + D+V A+   R   R      +L     P   E  EE+        +  S  + 
Sbjct: 172 TMREDYSDKVKASHWSRSPPRPPRERFELGDGRKPVKEEKMEERDLLSDLQDISDSERKT 231

Query: 315 EEEEEEEEEEEAEEEEEEEDSEEAPPPLSPPQPASPAEEDKMPPYDEQTQAFIDAAQEAR 374
              E    E  +  EEEEE+ EE     S  + +   EE++    +E      +A++++ 
Sbjct: 232 SSAESSSAESGSGSEEEEEEEEEEEEEGSTSEESEEEEEEEEEEEEETGSNSEEASEQSA 291

Query: 375 NKFEEAERSLKDMEESIRNL----EQEISFDFGPNGEFAYLYS----QCYELTTNEYV-- 424
            +  E E S  +  E+  +L    E     D G + E          Q   LT  +YV  
Sbjct: 292 EEVSEEEMSEDEERENENHLLVVPESRFDRDSGESEEAEEEVGEGTPQSSALTEGDYVPD 351

Query: 425 -YRLCPFKLVSQKPK 438
              L P +L  + PK
Sbjct: 352 SPALSPIELKQELPK 366



 Score = 30.0 bits (66), Expect = 5.4
 Identities = 31/144 (21%), Positives = 53/144 (36%), Gaps = 6/144 (4%)

Query: 51  VNDDYCDCKDGSDEPGTAACPNGSFHCTNTGYKPLYIPSNRVNDGVCDCCDGTDEYNSGV 110
           + +DY D    S    +   P         G KP+        D + D  D +D      
Sbjct: 173 MREDYSDKVKASHWSRSPPRPPRERFELGDGRKPVKEEKMEERDLLSDLQDISDSERKTS 232

Query: 111 ICENTCKEKGRKERESLQQMAEVTREGFRLKKILIEDWKKAREEKQKKLIELQAGKKSLE 170
             E++  E G    E  ++  E   EG   ++   E+ ++  EE++      +A ++S E
Sbjct: 233 SAESSSAESGSGSEEEEEEEEEEEEEGSTSEESEEEEEEEEEEEEETGSNSEEASEQSAE 292

Query: 171 DQVEMLRTVKEEAEKPEREAKEQH 194
           +  E      EE  + E    E H
Sbjct: 293 EVSE------EEMSEDEERENENH 310


>gi|148763345 cell division cycle 2-like 2 isoform 4 [Homo sapiens]
          Length = 770

 Score = 62.0 bits (149), Expect = 1e-09
 Identities = 73/284 (25%), Positives = 118/284 (41%), Gaps = 27/284 (9%)

Query: 117 KEKGRKERESLQQMAEVTREGFRLKKILIEDWKKARE-EKQKKLIELQAGKKSLEDQVEM 175
           K++ RKE+    ++ E  RE  R K+   E  K  RE E+QK+    +   +   D++E 
Sbjct: 101 KDEKRKEKWKHARVKE--REHERRKRHREEQDKARREWERQKRREMAREHSRRERDRLEQ 158

Query: 176 LRTVKEEAEKPEREAKEQHQKLWEEQLAAAKAQQEQ---ELAADAFKELDDDMDGTVSVT 232
           L   +E   K   + KEQ ++   E+ A  + ++ +   E++A   + + +D    V  +
Sbjct: 159 LERKRERERKMREQQKEQREQKERERRAEERRKEREARREVSAH-HRTMREDYSDKVKAS 217

Query: 233 ELQTHP-----ELDTDGDGALSEAEAQALLSGDTQTDATSFYDRVWAAIRDKYRSEALPT 287
                P     E    GDG     E + +   D  +D           I D  R  +   
Sbjct: 218 HWSRSPPRPPRERFELGDGRKPVKE-EKMEERDLLSDLQD--------ISDSERKTSSAE 268

Query: 288 DLPAPSAPDLTEPKEEQPPVPSSPTEEEEEEEEEEEEEAEEEEEEEDSEEAPPPLSPPQP 347
              A S     E +EE+       +  EE EEEEEEEE EEEE   +SEEA       Q 
Sbjct: 269 SSSAESGSGSEEEEEEEEEEEEEGSTSEESEEEEEEEEEEEEETGSNSEEA-----SEQS 323

Query: 348 ASPAEEDKMPPYDEQTQAFIDAAQEARNKFEEAERSLKDMEESI 391
           A    E++M   DE+ +          ++F+      ++ EE +
Sbjct: 324 AEEVSEEEMSE-DEERENENHLLVVPESRFDRDSGESEEAEEEV 366



 Score = 49.3 bits (116), Expect = 9e-06
 Identities = 78/360 (21%), Positives = 136/360 (37%), Gaps = 52/360 (14%)

Query: 107 NSGVICENTCKEKGRKERESL-----QQMAEVTREGFRLKKILIEDWKKAREEKQKKLIE 161
           NS    E++ +++G +E +SL     QQM+   +   R  +   E WK AR ++++    
Sbjct: 64  NSPYRREDSMEDRG-EEDDSLAIKPPQQMSRKEKVHHRKDEKRKEKWKHARVKERE---- 118

Query: 162 LQAGKKSLEDQVEMLRTVKEEAEKPEREAKEQHQKLWEEQLAAAKAQQEQELAADAFKEL 221
                               E  K  RE +++ ++ WE Q     A++      D  ++L
Sbjct: 119 -------------------HERRKRHREEQDKARREWERQKRREMAREHSRRERDRLEQL 159

Query: 222 DDDMDGTVSVTELQTHP----ELDTDGDGALSEAEAQALLSGDTQTDATSFYDRVWAA-- 275
           +   +    + E Q       E +   +    E EA+  +S   +T    + D+V A+  
Sbjct: 160 ERKRERERKMREQQKEQREQKERERRAEERRKEREARREVSAHHRTMREDYSDKVKASHW 219

Query: 276 IRDKYRSEALPTDLPAPSAPDLTEPKEEQP------PVPSSPTEEEEEEEEEEEEEAEEE 329
            R   R      +L     P   E  EE+        +  S  +    E    E  +  E
Sbjct: 220 SRSPPRPPRERFELGDGRKPVKEEKMEERDLLSDLQDISDSERKTSSAESSSAESGSGSE 279

Query: 330 EEEEDSEEAPPPLSPPQPASPAEEDKMPPYDEQTQAFIDAAQEARNKFEEAERSLKDMEE 389
           EEEE+ EE     S  + +   EE++    +E      +A++++  +  E E S  +  E
Sbjct: 280 EEEEEEEEEEEEGSTSEESEEEEEEEEEEEEETGSNSEEASEQSAEEVSEEEMSEDEERE 339

Query: 390 SIRNL----EQEISFDFGPNGEFAYLYS----QCYELTTNEYV---YRLCPFKLVSQKPK 438
           +  +L    E     D G + E          Q   LT  +YV     L P +L  + PK
Sbjct: 340 NENHLLVVPESRFDRDSGESEEAEEEVGEGTPQSSALTEGDYVPDSPALLPIELKQELPK 399



 Score = 30.0 bits (66), Expect = 5.4
 Identities = 31/144 (21%), Positives = 53/144 (36%), Gaps = 6/144 (4%)

Query: 51  VNDDYCDCKDGSDEPGTAACPNGSFHCTNTGYKPLYIPSNRVNDGVCDCCDGTDEYNSGV 110
           + +DY D    S    +   P         G KP+        D + D  D +D      
Sbjct: 206 MREDYSDKVKASHWSRSPPRPPRERFELGDGRKPVKEEKMEERDLLSDLQDISDSERKTS 265

Query: 111 ICENTCKEKGRKERESLQQMAEVTREGFRLKKILIEDWKKAREEKQKKLIELQAGKKSLE 170
             E++  E G    E  ++  E   EG   ++   E+ ++  EE++      +A ++S E
Sbjct: 266 SAESSSAESGSGSEEEEEEEEEEEEEGSTSEESEEEEEEEEEEEEETGSNSEEASEQSAE 325

Query: 171 DQVEMLRTVKEEAEKPEREAKEQH 194
           +  E      EE  + E    E H
Sbjct: 326 EVSE------EEMSEDEERENENH 343


>gi|4505257 moesin [Homo sapiens]
          Length = 577

 Score = 62.0 bits (149), Expect = 1e-09
 Identities = 75/311 (24%), Positives = 133/311 (42%), Gaps = 46/311 (14%)

Query: 86  YIPSNRVNDGVCDCCDGTDEYNSGVICENTCKEKGRKERESLQQMAEVTREGFRLKKI-- 143
           Y P  R+N  +   C G  E             + + +   +QQM    RE    K++  
Sbjct: 270 YAPRLRINKRILALCMGNHELYM---------RRRKPDTIEVQQMKAQAREEKHQKQMER 320

Query: 144 -LIEDWKKARE--EKQKKLIELQAGKKSLEDQVEMLRTVKEEAEKPEREAKEQHQKLWEE 200
            ++E+ KK RE  EK+K+ IE     +  E+ +E L+ ++E+ +K ++E +EQ ++  E 
Sbjct: 321 AMLENEKKKREMAEKEKEKIE-----REKEELMERLKQIEEQTKKAQQELEEQTRRALEL 375

Query: 201 QLAAAKAQQEQELAADAFKELDDDMDGTVSVTELQTHPELDTDGDGALSEAEAQALLSGD 260
           +    +AQ E E  A   +E ++  +  +  +  Q      T    AL  AE  A +S  
Sbjct: 376 EQERKRAQSEAEKLAKERQEAEEAKEALLQASRDQK----KTQEQLALEMAELTARIS-- 429

Query: 261 TQTDATSFYDRVWAAIRDKYRSEALPTDLPAPSA-PDLTEPKEEQPPVPSSP--TEEEEE 317
            Q +            R K  SEA+     A     DL + + E     S+P   E  E 
Sbjct: 430 -QLEMA----------RQKKESEAVEWQQKAQMVQEDLEKTRAELKTAMSTPHVAEPAEN 478

Query: 318 EEEEEEEEAEEEEEEEDSEEAPPPLSPPQPASPAEEDKMPPYDEQTQAFIDA-AQEARNK 376
           E++E++E   E   +  ++      S  +  + AE+      +E+ Q  + A   E  N 
Sbjct: 479 EQDEQDENGAEASADLRADAMAKDRSEEERTTEAEK------NERVQKHLKALTSELANA 532

Query: 377 FEEAERSLKDM 387
            +E++++  DM
Sbjct: 533 RDESKKTANDM 543



 Score = 35.0 bits (79), Expect = 0.17
 Identities = 20/76 (26%), Positives = 40/76 (52%), Gaps = 3/76 (3%)

Query: 315 EEEEEEEEEEEAEEEEEEEDSEEAPPPLSPPQPASPAEEDKMPPYDEQTQAFIDAAQEAR 374
           E E+++ E  E E+E+ E + EE    L   +  +   + ++   +EQT+  ++  QE +
Sbjct: 324 ENEKKKREMAEKEKEKIEREKEELMERLKQIEEQTKKAQQEL---EEQTRRALELEQERK 380

Query: 375 NKFEEAERSLKDMEES 390
               EAE+  K+ +E+
Sbjct: 381 RAQSEAEKLAKERQEA 396


>gi|16332364 cell division cycle 2-like 1 (PITSLRE proteins) isoform
           5 [Homo sapiens]
          Length = 748

 Score = 61.6 bits (148), Expect = 2e-09
 Identities = 74/289 (25%), Positives = 117/289 (40%), Gaps = 30/289 (10%)

Query: 117 KEKGRKERESLQ-----QMAEVTREGFRLKKILIEDWKKARE-EKQKKLIELQAGKKSLE 170
           KEK R    S +     ++ E  RE  R K+   E  K  RE E+QK+    +   +   
Sbjct: 72  KEKRRHRSHSAEGGKHARVKEKEREHERRKRHREEQDKARREWERQKRREMAREHSRRER 131

Query: 171 DQVEMLRTVKEEAEKPEREAKEQHQKLWEEQLAAAKAQQEQ---ELAADAFKELDDDMDG 227
           D++E L   +E   K   + KEQ ++   E+ A  + ++ +   E++A   + + +D   
Sbjct: 132 DRLEQLERKRERERKMREQQKEQREQKERERRAEERRKEREARREVSAH-HRTMREDYSD 190

Query: 228 TVSVTELQTHP-----ELDTDGDGALSEAEAQALLSGDTQTDATSFYDRVWAAIRDKYRS 282
            V  +     P     E    GDG     E + +   D  +D           I D  R 
Sbjct: 191 KVKASHWSRSPPRPPRERFELGDGRKPVKE-EKMEERDLLSDLQD--------ISDSERK 241

Query: 283 EALPTDLPAPSAPDLTEPKEEQPPVPSSPTEEEEEEEEEEEEEAEEEEEEEDSEEAPPPL 342
            +      A S     E +EE+       +  EE EEEEEEEE EEEE   +SEEA    
Sbjct: 242 TSSAESSSAESGSGSEEEEEEEEEEEEEGSTSEESEEEEEEEEEEEEETGSNSEEA---- 297

Query: 343 SPPQPASPAEEDKMPPYDEQTQAFIDAAQEARNKFEEAERSLKDMEESI 391
              Q A    E++M   DE+ +          ++F+      ++ EE +
Sbjct: 298 -SEQSAEEVSEEEMSE-DEERENENHLLVVPESRFDRDSGESEEAEEEV 344



 Score = 52.0 bits (123), Expect = 1e-06
 Identities = 79/360 (21%), Positives = 143/360 (39%), Gaps = 40/360 (11%)

Query: 107 NSGVICENTCKEKGRKERESL-----QQMAEVTREGFRLKKILIEDWKKAREEKQKKLIE 161
           NS    E++ +++G +E +SL     QQM+       R +K+     +K +E+++ +   
Sbjct: 30  NSPYRREDSMEDRG-EEDDSLAIKPPQQMS-------RKEKVHHRKDEKRKEKRRHRSHS 81

Query: 162 LQAGKKSLEDQVEMLRTVKEEAEKPEREAKEQHQKLWEEQLAAAKAQQEQELAADAFKEL 221
            + GK +   + E     + E  K  RE +++ ++ WE Q     A++      D  ++L
Sbjct: 82  AEGGKHARVKEKER----EHERRKRHREEQDKARREWERQKRREMAREHSRRERDRLEQL 137

Query: 222 DDDMDGTVSVTELQTHP----ELDTDGDGALSEAEAQALLSGDTQTDATSFYDRVWAA-- 275
           +   +    + E Q       E +   +    E EA+  +S   +T    + D+V A+  
Sbjct: 138 ERKRERERKMREQQKEQREQKERERRAEERRKEREARREVSAHHRTMREDYSDKVKASHW 197

Query: 276 IRDKYRSEALPTDLPAPSAPDLTEPKEEQP------PVPSSPTEEEEEEEEEEEEEAEEE 329
            R   R      +L     P   E  EE+        +  S  +    E    E  +  E
Sbjct: 198 SRSPPRPPRERFELGDGRKPVKEEKMEERDLLSDLQDISDSERKTSSAESSSAESGSGSE 257

Query: 330 EEEEDSEEAPPPLSPPQPASPAEEDKMPPYDEQTQAFIDAAQEARNKFEEAERSLKDMEE 389
           EEEE+ EE     S  + +   EE++    +E      +A++++  +  E E S  +  E
Sbjct: 258 EEEEEEEEEEEEGSTSEESEEEEEEEEEEEEETGSNSEEASEQSAEEVSEEEMSEDEERE 317

Query: 390 SIRNL----EQEISFDFGPNGEFAYLYS----QCYELTTNEYV---YRLCPFKLVSQKPK 438
           +  +L    E     D G + E          Q   LT  +YV     L P +L  + PK
Sbjct: 318 NENHLLVVPESRFDRDSGESEEAEEEVGEGTPQSSALTEGDYVPDSPALSPIELKQELPK 377



 Score = 30.0 bits (66), Expect = 5.4
 Identities = 31/144 (21%), Positives = 53/144 (36%), Gaps = 6/144 (4%)

Query: 51  VNDDYCDCKDGSDEPGTAACPNGSFHCTNTGYKPLYIPSNRVNDGVCDCCDGTDEYNSGV 110
           + +DY D    S    +   P         G KP+        D + D  D +D      
Sbjct: 184 MREDYSDKVKASHWSRSPPRPPRERFELGDGRKPVKEEKMEERDLLSDLQDISDSERKTS 243

Query: 111 ICENTCKEKGRKERESLQQMAEVTREGFRLKKILIEDWKKAREEKQKKLIELQAGKKSLE 170
             E++  E G    E  ++  E   EG   ++   E+ ++  EE++      +A ++S E
Sbjct: 244 SAESSSAESGSGSEEEEEEEEEEEEEGSTSEESEEEEEEEEEEEEETGSNSEEASEQSAE 303

Query: 171 DQVEMLRTVKEEAEKPEREAKEQH 194
           +  E      EE  + E    E H
Sbjct: 304 EVSE------EEMSEDEERENENH 321


>gi|16332358 cell division cycle 2-like 1 (PITSLRE proteins) isoform
           2 [Homo sapiens]
          Length = 782

 Score = 61.6 bits (148), Expect = 2e-09
 Identities = 74/289 (25%), Positives = 117/289 (40%), Gaps = 30/289 (10%)

Query: 117 KEKGRKERESLQ-----QMAEVTREGFRLKKILIEDWKKARE-EKQKKLIELQAGKKSLE 170
           KEK R    S +     ++ E  RE  R K+   E  K  RE E+QK+    +   +   
Sbjct: 106 KEKRRHRSHSAEGGKHARVKEKEREHERRKRHREEQDKARREWERQKRREMAREHSRRER 165

Query: 171 DQVEMLRTVKEEAEKPEREAKEQHQKLWEEQLAAAKAQQEQ---ELAADAFKELDDDMDG 227
           D++E L   +E   K   + KEQ ++   E+ A  + ++ +   E++A   + + +D   
Sbjct: 166 DRLEQLERKRERERKMREQQKEQREQKERERRAEERRKEREARREVSAH-HRTMREDYSD 224

Query: 228 TVSVTELQTHP-----ELDTDGDGALSEAEAQALLSGDTQTDATSFYDRVWAAIRDKYRS 282
            V  +     P     E    GDG     E + +   D  +D           I D  R 
Sbjct: 225 KVKASHWSRSPPRPPRERFELGDGRKPVKE-EKMEERDLLSDLQD--------ISDSERK 275

Query: 283 EALPTDLPAPSAPDLTEPKEEQPPVPSSPTEEEEEEEEEEEEEAEEEEEEEDSEEAPPPL 342
            +      A S     E +EE+       +  EE EEEEEEEE EEEE   +SEEA    
Sbjct: 276 TSSAESSSAESGSGSEEEEEEEEEEEEEGSTSEESEEEEEEEEEEEEETGSNSEEA---- 331

Query: 343 SPPQPASPAEEDKMPPYDEQTQAFIDAAQEARNKFEEAERSLKDMEESI 391
              Q A    E++M   DE+ +          ++F+      ++ EE +
Sbjct: 332 -SEQSAEEVSEEEMSE-DEERENENHLLVVPESRFDRDSGESEEAEEEV 378



 Score = 52.0 bits (123), Expect = 1e-06
 Identities = 79/360 (21%), Positives = 143/360 (39%), Gaps = 40/360 (11%)

Query: 107 NSGVICENTCKEKGRKERESL-----QQMAEVTREGFRLKKILIEDWKKAREEKQKKLIE 161
           NS    E++ +++G +E +SL     QQM+       R +K+     +K +E+++ +   
Sbjct: 64  NSPYRREDSMEDRG-EEDDSLAIKPPQQMS-------RKEKVHHRKDEKRKEKRRHRSHS 115

Query: 162 LQAGKKSLEDQVEMLRTVKEEAEKPEREAKEQHQKLWEEQLAAAKAQQEQELAADAFKEL 221
            + GK +   + E     + E  K  RE +++ ++ WE Q     A++      D  ++L
Sbjct: 116 AEGGKHARVKEKER----EHERRKRHREEQDKARREWERQKRREMAREHSRRERDRLEQL 171

Query: 222 DDDMDGTVSVTELQTHP----ELDTDGDGALSEAEAQALLSGDTQTDATSFYDRVWAA-- 275
           +   +    + E Q       E +   +    E EA+  +S   +T    + D+V A+  
Sbjct: 172 ERKRERERKMREQQKEQREQKERERRAEERRKEREARREVSAHHRTMREDYSDKVKASHW 231

Query: 276 IRDKYRSEALPTDLPAPSAPDLTEPKEEQP------PVPSSPTEEEEEEEEEEEEEAEEE 329
            R   R      +L     P   E  EE+        +  S  +    E    E  +  E
Sbjct: 232 SRSPPRPPRERFELGDGRKPVKEEKMEERDLLSDLQDISDSERKTSSAESSSAESGSGSE 291

Query: 330 EEEEDSEEAPPPLSPPQPASPAEEDKMPPYDEQTQAFIDAAQEARNKFEEAERSLKDMEE 389
           EEEE+ EE     S  + +   EE++    +E      +A++++  +  E E S  +  E
Sbjct: 292 EEEEEEEEEEEEGSTSEESEEEEEEEEEEEEETGSNSEEASEQSAEEVSEEEMSEDEERE 351

Query: 390 SIRNL----EQEISFDFGPNGEFAYLYS----QCYELTTNEYV---YRLCPFKLVSQKPK 438
           +  +L    E     D G + E          Q   LT  +YV     L P +L  + PK
Sbjct: 352 NENHLLVVPESRFDRDSGESEEAEEEVGEGTPQSSALTEGDYVPDSPALSPIELKQELPK 411



 Score = 30.0 bits (66), Expect = 5.4
 Identities = 31/144 (21%), Positives = 53/144 (36%), Gaps = 6/144 (4%)

Query: 51  VNDDYCDCKDGSDEPGTAACPNGSFHCTNTGYKPLYIPSNRVNDGVCDCCDGTDEYNSGV 110
           + +DY D    S    +   P         G KP+        D + D  D +D      
Sbjct: 218 MREDYSDKVKASHWSRSPPRPPRERFELGDGRKPVKEEKMEERDLLSDLQDISDSERKTS 277

Query: 111 ICENTCKEKGRKERESLQQMAEVTREGFRLKKILIEDWKKAREEKQKKLIELQAGKKSLE 170
             E++  E G    E  ++  E   EG   ++   E+ ++  EE++      +A ++S E
Sbjct: 278 SAESSSAESGSGSEEEEEEEEEEEEEGSTSEESEEEEEEEEEEEEETGSNSEEASEQSAE 337

Query: 171 DQVEMLRTVKEEAEKPEREAKEQH 194
           +  E      EE  + E    E H
Sbjct: 338 EVSE------EEMSEDEERENENH 355


>gi|239756241 PREDICTED: golgi autoantigen, golgin subfamily a-like
           [Homo sapiens]
          Length = 899

 Score = 61.2 bits (147), Expect = 2e-09
 Identities = 62/294 (21%), Positives = 131/294 (44%), Gaps = 34/294 (11%)

Query: 113 ENTCKEKGRKERESLQQMAEVTREGFRLKKILIEDWKKA--REEKQKKLIELQAGKKSLE 170
           E+   E+  K R+  Q+M +      R++K   E  KK   +EEK ++   ++  +K + 
Sbjct: 543 EDQMWEQEEKMRDQEQKMWDQEE---RMEKKTQEQEKKTWDQEEKMREEERMREREKKMR 599

Query: 171 DQVEMLRTVKEEAEKPEREAKEQHQKLWEEQLAAAKAQQEQELAADAFKELDDDMDGTVS 230
           ++ EM+R  +E+ ++ E + +EQ +K+WE++    + +++     +   E ++ M     
Sbjct: 600 EEEEMMREQEEKMQEQEEKMQEQEEKMWEQEEKMQEQEEKMWEQEEKMWEQEEKMWEQQR 659

Query: 231 VTE----LQTHPELDTDGDGALSEAE--AQALLSGDTQTDATSFYDRVWAAIRDKYRSEA 284
           + E    L  H ++         E +   Q  +   TQ      +D      ++K R E 
Sbjct: 660 LPEQKEKLWEHEKMQEQEKMQEQEEKIWEQEKMEKKTQEQEKKTWD------QEKMREE- 712

Query: 285 LPTDLPAPSAPDLTEPKEEQPPVPSSPTEEEEEEEEEEEEEAEEEEEEEDSEEAPPPLSP 344
                       + E +++         E+EE+ +E+EE+  E+EEE  + EE       
Sbjct: 713 ----------ESMREREKKMREEEEMMREQEEKMQEQEEKMQEQEEEMWEQEEK----MW 758

Query: 345 PQPASPAEEDKMPPYDEQTQAFIDAAQEARNKFEEAERSLKDMEESIRNLEQEI 398
            Q     E+ ++P  +++ + +     + + K  E E  ++D EE +R  E+++
Sbjct: 759 EQEEKMWEQQRLP--EQKEKLWEHEKMQEQEKIWEQEEKMRDQEEKMRGQEEKM 810



 Score = 57.4 bits (137), Expect = 3e-08
 Identities = 56/299 (18%), Positives = 129/299 (43%), Gaps = 21/299 (7%)

Query: 117 KEKGRKERESLQQMAEVTREGFRLKKILIEDWKKAREEKQKKLIELQAGKKSLEDQVEM- 175
           +EK +K+ E++ +  E   +  RL +   + W++ + ++Q++ I  Q  K  + DQ EM 
Sbjct: 470 EEKMQKQEENMWEQEEKEWQQQRLPEQKEKLWEQEKMQEQEEKIWEQEEK--IRDQEEMW 527

Query: 176 -----------LRTVKEEAEKPEREAKEQHQKLWEEQLAAAKAQQEQELAA-DAFKELDD 223
                      +R  +++  + E + ++Q QK+W+++    K  QEQE    D  +++ +
Sbjct: 528 GQEKKMWRQEKMREQEDQMWEQEEKMRDQEQKMWDQEERMEKKTQEQEKKTWDQEEKMRE 587

Query: 224 DMDGTVSVTELQTHPELDTDGDGALSEAE----AQALLSGDTQTDATSFYDRVWAAIRDK 279
           +        +++   E+  + +  + E E     Q     + +       +++W      
Sbjct: 588 EERMREREKKMREEEEMMREQEEKMQEQEEKMQEQEEKMWEQEEKMQEQEEKMWEQEEKM 647

Query: 280 YRSEALPTDLPAPSAPDLTEPKEEQPPVPSSPTEEEEEEEEEEEEEAEEEEEEEDSEEAP 339
           +  E    +      P+  E   E   +      +E+EE+  E+E+ E++ +E++ +   
Sbjct: 648 WEQEEKMWE--QQRLPEQKEKLWEHEKMQEQEKMQEQEEKIWEQEKMEKKTQEQEKKTWD 705

Query: 340 PPLSPPQPASPAEEDKMPPYDEQTQAFIDAAQEARNKFEEAERSLKDMEESIRNLEQEI 398
                 + +    E KM   +E  +   +  QE   K +E E  + + EE +   E+++
Sbjct: 706 QEKMREEESMREREKKMREEEEMMREQEEKMQEQEEKMQEQEEEMWEQEEKMWEQEEKM 764



 Score = 53.9 bits (128), Expect = 4e-07
 Identities = 58/306 (18%), Positives = 125/306 (40%), Gaps = 25/306 (8%)

Query: 113 ENTCKEKGRKERESLQQMAEVTREGFRLKKILIEDWKKAREEKQK-------------KL 159
           E   +E+  K  E  ++M E   + +R ++ L E  K+ RE++QK             +L
Sbjct: 347 EEQMQEQEEKMWEQEEKMREQEEKMWRQEERLWEQEKQMREQEQKMRDQEERMWEQDERL 406

Query: 160 IELQAGKKSLEDQVEMLRTVKEEAEKPEREAK--EQHQKLWEEQL---AAAKAQQEQELA 214
            E +   +  E   E +  ++EE +  E+E K  +Q +K+ EE+       K ++E+E  
Sbjct: 407 REKEERMREQEKMWEQVEKMREEKKMQEQEKKTRDQEEKMQEEERIREREKKMREEEETM 466

Query: 215 ADAFKELDDDMDGTVSVTELQTHPELDTDGDGALSEAEAQALLSGD--TQTDATSFYDRV 272
            +  +++    +      E +   +   +    L E E           Q +     + +
Sbjct: 467 REQEEKMQKQEENMWEQEEKEWQQQRLPEQKEKLWEQEKMQEQEEKIWEQEEKIRDQEEM 526

Query: 273 WAAIRDKYRSEALPTDLPAPSAPDLTEPKEEQPPVPSSPTEEEEEEEEEEEEEAEEEEEE 332
           W   +  +R E +           + E +E+         ++EE  E++ +E+ ++  ++
Sbjct: 527 WGQEKKMWRQEKM-----REQEDQMWEQEEKMRDQEQKMWDQEERMEKKTQEQEKKTWDQ 581

Query: 333 EDSEEAPPPLSPPQPASPAEEDKMPPYDEQTQAFIDAAQEARNKFEEAERSLKDMEESIR 392
           E+       +   +     EE+ M   +E+ Q   +  QE   K  E E  +++ EE + 
Sbjct: 582 EEKMREEERMREREKKMREEEEMMREQEEKMQEQEEKMQEQEEKMWEQEEKMQEQEEKMW 641

Query: 393 NLEQEI 398
             E+++
Sbjct: 642 EQEEKM 647



 Score = 53.5 bits (127), Expect = 5e-07
 Identities = 65/322 (20%), Positives = 136/322 (42%), Gaps = 48/322 (14%)

Query: 117 KEKGRKERESLQQMAEVTREGFRLKKILIEDWKKAREEKQKKLIE--LQAGKKSLEDQVE 174
           KE+  +E+E + +  E  RE    +K + E  KK R++++K   E  ++  +K + ++ E
Sbjct: 409 KEERMREQEKMWEQVEKMRE----EKKMQEQEKKTRDQEEKMQEEERIREREKKMREEEE 464

Query: 175 MLRTVKEEAEKPE-------------REAKEQHQKLWEEQLAAAKAQQEQELAADAFKEL 221
            +R  +E+ +K E             +   EQ +KLWE++    K Q+++E   +  +++
Sbjct: 465 TMREQEEKMQKQEENMWEQEEKEWQQQRLPEQKEKLWEQE----KMQEQEEKIWEQEEKI 520

Query: 222 DDDMDGTVSVTELQTHPELDTDGDGALSEAE-----------AQALLSGDTQTDATSFYD 270
            D  +      ++    ++    D    + E            +  +   TQ      +D
Sbjct: 521 RDQEEMWGQEKKMWRQEKMREQEDQMWEQEEKMRDQEQKMWDQEERMEKKTQEQEKKTWD 580

Query: 271 -----RVWAAIRDKYRSEALPTDLPAPSAPDLTEPKEEQPPVPSSPTEEEEEEEEEEEEE 325
                R    +R++ +      ++       + E +E+         E+EE+ +E+EE+ 
Sbjct: 581 QEEKMREEERMREREKKMREEEEMMREQEEKMQEQEEKMQEQEEKMWEQEEKMQEQEEKM 640

Query: 326 AEEEEEEEDSEEA--PPPLSPPQPASPAEEDKMPPYD--EQTQAFIDAAQEARNKFEEAE 381
            E+EE+  + EE        P Q     E +KM   +  ++ +  I   ++   K +E E
Sbjct: 641 WEQEEKMWEQEEKMWEQQRLPEQKEKLWEHEKMQEQEKMQEQEEKIWEQEKMEKKTQEQE 700

Query: 382 RSLKDM-----EESIRNLEQEI 398
           +   D      EES+R  E+++
Sbjct: 701 KKTWDQEKMREEESMREREKKM 722



 Score = 47.8 bits (112), Expect = 3e-05
 Identities = 63/294 (21%), Positives = 123/294 (41%), Gaps = 28/294 (9%)

Query: 123 ERESLQ-QMAEVTREGFRLKKILIE-DWKKAREEKQKKLIELQAGKKSLEDQVEMLRTVK 180
           E+  +Q  + E+ R+  R K +L +      +EE  ++  EL+  +K +  Q E +   +
Sbjct: 240 EKSEIQLNVKELKRKLERAKFLLPQVQTNTLQEEMWRQEEELREQEKKIRKQEEKMWRQE 299

Query: 181 EEAEKPEREAKEQHQKLWEEQLAAAKAQQEQELAADAFKELDDDMDGTVSVTELQTHPEL 240
           E   + E + +EQ +K+W ++      +QE+EL  +  KEL +  +      ++Q   E 
Sbjct: 300 ERLREQEGKMREQEEKMWRQE--KRLREQEKEL-REQEKELREQKELREQEEQMQEQEEK 356

Query: 241 DTDGDGALSEAE-----------AQALLSGDTQTDATSFYDRVW---AAIRDKYRSEALP 286
             + +  + E E            Q     + +       +R+W     +R+K       
Sbjct: 357 MWEQEEKMREQEEKMWRQEERLWEQEKQMREQEQKMRDQEERMWEQDERLREK-EERMRE 415

Query: 287 TDLPAPSAPDLTEPKEEQPPVPSSPTEEEEEEEEE--EEEEAEEEEEEEDSEEAPPPLSP 344
            +        + E K+ Q     +  +EE+ +EEE   E E +  EEEE   E    +  
Sbjct: 416 QEKMWEQVEKMREEKKMQEQEKKTRDQEEKMQEEERIREREKKMREEEETMREQEEKMQK 475

Query: 345 PQPASPAEEDKMPPYDEQTQAFIDAAQE--ARNKFEEAERSLKDMEESIRNLEQ 396
            +     +E+K    + Q Q   +  ++   + K +E E  + + EE IR+ E+
Sbjct: 476 QEENMWEQEEK----EWQQQRLPEQKEKLWEQEKMQEQEEKIWEQEEKIRDQEE 525



 Score = 44.7 bits (104), Expect = 2e-04
 Identities = 61/288 (21%), Positives = 119/288 (41%), Gaps = 38/288 (13%)

Query: 117 KEKGRKERESLQQMAEVTREGFRLKKILIEDWKKAREEKQKKLIELQAGKKSLEDQVEML 176
           +EK  +E++ L++  E  +E    ++ + E  +K RE+++K    +   ++ L +Q + +
Sbjct: 333 QEKELREQKELREQEEQMQEQ---EEKMWEQEEKMREQEEK----MWRQEERLWEQEKQM 385

Query: 177 RTVKEEAEKPEREAKEQHQKL--WEEQLAAAKAQQEQELAADAFKELDDDMDGTVSVTEL 234
           R  +++    E    EQ ++L   EE++   +   EQ       K++ +    T    E 
Sbjct: 386 REQEQKMRDQEERMWEQDERLREKEERMREQEKMWEQVEKMREEKKMQEQEKKTRDQEEK 445

Query: 235 QTHPELDTDGDGALSEAEAQALLSGDTQTDATSFYDRVWAAIRDKYRSEALPTDLPAPSA 294
               E   + +  + E E       + +       + +W     +++ + LP        
Sbjct: 446 MQEEERIREREKKMREEEE---TMREQEEKMQKQEENMWEQEEKEWQQQRLP-------- 494

Query: 295 PDLTEPKEEQPPVPSSPTEEEEEEEEEEEEEAEEEEEEEDSEE--APPPLSPPQPASPAE 352
               E KE+          E+E+ +E+EE+  E+EE+  D EE          Q     +
Sbjct: 495 ----EQKEK--------LWEQEKMQEQEEKIWEQEEKIRDQEEMWGQEKKMWRQEKMREQ 542

Query: 353 EDKMPPYDE----QTQAFIDAAQEARNKFEEAERSLKDMEESIRNLEQ 396
           ED+M   +E    Q Q   D  +    K +E E+   D EE +R  E+
Sbjct: 543 EDQMWEQEEKMRDQEQKMWDQEERMEKKTQEQEKKTWDQEEKMREEER 590



 Score = 35.4 bits (80), Expect = 0.13
 Identities = 20/85 (23%), Positives = 42/85 (49%), Gaps = 3/85 (3%)

Query: 314 EEEEEEEEEEEEAEEEEEEEDSEEAPPPLSPPQPASPAEEDKMPPYDEQTQAFIDAAQEA 373
           E+E+E  E+E+E  E++E  + EE    +   +     +E+KM   +E+     +   E 
Sbjct: 325 EQEKELREQEKELREQKELREQEEQ---MQEQEEKMWEQEEKMREQEEKMWRQEERLWEQ 381

Query: 374 RNKFEEAERSLKDMEESIRNLEQEI 398
             +  E E+ ++D EE +   ++ +
Sbjct: 382 EKQMREQEQKMRDQEERMWEQDERL 406



 Score = 35.4 bits (80), Expect = 0.13
 Identities = 20/86 (23%), Positives = 40/86 (46%)

Query: 313 EEEEEEEEEEEEEAEEEEEEEDSEEAPPPLSPPQPASPAEEDKMPPYDEQTQAFIDAAQE 372
           +E  E+E+E  E+ E  E+EE  +E    +   +     +E+KM   +E+        +E
Sbjct: 328 KELREQEKELREQKELREQEEQMQEQEEKMWEQEEKMREQEEKMWRQEERLWEQEKQMRE 387

Query: 373 ARNKFEEAERSLKDMEESIRNLEQEI 398
              K  + E  + + +E +R  E+ +
Sbjct: 388 QEQKMRDQEERMWEQDERLREKEERM 413



 Score = 33.5 bits (75), Expect = 0.49
 Identities = 19/85 (22%), Positives = 45/85 (52%), Gaps = 3/85 (3%)

Query: 117 KEKGRKERESLQQMAEVTREGFRLKKILIEDWKKAREEKQKKLIELQAGKKSLEDQVEML 176
           +E+  ++ E + +  E   E  RL +   + W+  + ++Q+K+ E +   + + DQ E +
Sbjct: 747 EEEMWEQEEKMWEQEEKMWEQQRLPEQKEKLWEHEKMQEQEKIWEQE---EKMRDQEEKM 803

Query: 177 RTVKEEAEKPEREAKEQHQKLWEEQ 201
           R  +E+    E + + Q +K+W ++
Sbjct: 804 RGQEEKMRGQEEKMRGQEEKMWGQE 828


>gi|155030232 proline, glutamic acid and leucine rich protein 1
           [Homo sapiens]
          Length = 1130

 Score = 61.2 bits (147), Expect = 2e-09
 Identities = 42/124 (33%), Positives = 57/124 (45%), Gaps = 13/124 (10%)

Query: 283 EALPTDLPAPSAPDLTEPKEEQPPVPSSPTEEEEEEEEEEEEEAEEEEEEEDSEEAPPPL 342
           + +P   P    P   E       + SS  EEEEEEEEEEEEE EEEEEE+  EE     
Sbjct: 859 QLVPEGTPGGGGPPALEEDLTVININSSDEEEEEEEEEEEEEEEEEEEEEDFEEE----- 913

Query: 343 SPPQPASPAEEDKMPPYDEQTQAFIDAAQEARNKFEEAERSLKDMEESIRNLEQEISFDF 402
                    EE+     +E+ + F +  +E   + EE E   ++ EE    LE+    +F
Sbjct: 914 ------EEDEEEYFEEEEEEEEEFEEEFEEEEGELEEEEE--EEDEEEEEELEEVEDLEF 965

Query: 403 GPNG 406
           G  G
Sbjct: 966 GTAG 969



 Score = 54.3 bits (129), Expect = 3e-07
 Identities = 53/227 (23%), Positives = 98/227 (43%), Gaps = 18/227 (7%)

Query: 146  EDWKKAREEKQKKLIELQAGKKSLEDQVEMLRTVKEEAEKPEREAKEQHQKLWEEQLAAA 205
            E+ ++  EE++++  E +  ++  ED+ E     +EE E+ E E +E+  +L EE+    
Sbjct: 891  EEEEEEEEEEEEEEEEEEDFEEEEEDEEEYFEEEEEEEEEFEEEFEEEEGELEEEE---- 946

Query: 206  KAQQEQELAADAFKELDDDMDGTVSVTELQTHPELDTDGDGALSEAEAQALLSGDTQTDA 265
              ++E E   +  +E++D   GT      +  P   T    AL   E+   +  + + + 
Sbjct: 947  --EEEDEEEEEELEEVEDLEFGTAGGEVEEGAPPPPTLPP-ALPPPESPPKVQPEPEPEP 1003

Query: 266  TSFYDRVWAAIRDKYRSEALPTDLPAPSAPDLTEPKEEQPPVPSSPTEEEEEEEEEEEEE 325
                +       ++  ++  PT  P          +E + P    P +E  EEE      
Sbjct: 1004 GLLLEVEEPGTEEERGADTAPTLAPEALPSQGEVEREGESPAAGPPPQELVEEEPSAPPT 1063

Query: 326  AEEEEEEEDSEEAPPPLSPPQPASPAEEDKMPPYDEQTQAFIDAAQE 372
              EEE E+ S++  PP     P +PAEE+       +T+   +A QE
Sbjct: 1064 LLEEETEDGSDKVQPP-----PETPAEEEM------ETETEAEALQE 1099



 Score = 49.3 bits (116), Expect = 9e-06
 Identities = 66/263 (25%), Positives = 102/263 (38%), Gaps = 42/263 (15%)

Query: 110  VICENTCKEKGRKERESLQQMAEVTREGFRLKKILIEDWKKAREEKQKKLIELQAGKKSL 169
            VI  N+  E+  +E E  ++  E   E         ED+++  E++++   E +  ++  
Sbjct: 880  VININSSDEEEEEEEEEEEEEEEEEEEE--------EDFEEEEEDEEEYFEEEEEEEEEF 931

Query: 170  EDQVEMLRTVKEEAEKPEREAKEQHQKLWE-EQLAAAKAQQEQELAADAFKELDDDMDGT 228
            E++ E      EE E  E E +E+ ++L E E L    A  E E  A     L   +   
Sbjct: 932  EEEFEEEEGELEEEE--EEEDEEEEEELEEVEDLEFGTAGGEVEEGAPPPPTLPPALPPP 989

Query: 229  VSVTELQTHPELDTDGDGALSEAEAQALLSGDTQTDATSFYDRVWAAIRDKYRSEALPTD 288
             S  ++Q  PE +    G L E E            A +       +  +  R    P  
Sbjct: 990  ESPPKVQPEPEPEP---GLLLEVEEPGTEEERGADTAPTLAPEALPSQGEVEREGESPAA 1046

Query: 289  LPAP---------SAPDLTEPKEE------QPPVPSSPTEEEEEEEEEEEEEAEEEEEE- 332
             P P         + P L E + E      QPP P +P EEE E E E E   E+E+++ 
Sbjct: 1047 GPPPQELVEEEPSAPPTLLEEETEDGSDKVQPP-PETPAEEEMETETEAEALQEKEQDDT 1105

Query: 333  -----------EDSEEAPPPLSP 344
                        D E+ PPP  P
Sbjct: 1106 AAMLADFIDCPPDDEKPPPPTEP 1128



 Score = 44.7 bits (104), Expect = 2e-04
 Identities = 55/237 (23%), Positives = 85/237 (35%), Gaps = 45/237 (18%)

Query: 180  KEEAEKPEREAKEQHQKLWEEQLAAAKAQQEQELAADAFKELDDDMDGTVSVTELQTHPE 239
            +EE E+ E E +E+ +   EE+    +  +E+E   + F+E  ++ +G +   E     E
Sbjct: 893  EEEEEEEEEEEEEEEEDFEEEEEDEEEYFEEEEEEEEEFEEEFEEEEGELEEEE----EE 948

Query: 240  LDTDGDGALSEAEAQALLSGDTQTDATSFYDRVWAAIRDKYRSEALPTDLPAPSAPDLTE 299
             D + +  L E E     +   + +                  E  P   P P+ P    
Sbjct: 949  EDEEEEEELEEVEDLEFGTAGGEVE------------------EGAP---PPPTLPPALP 987

Query: 300  PKEEQPPVPSSPTEEEEEEEEEEEEEAEEEEE-----------------EEDSEEAPPPL 342
            P E  P V   P E E     E EE   EEE                  E + E   P  
Sbjct: 988  PPESPPKVQPEP-EPEPGLLLEVEEPGTEEERGADTAPTLAPEALPSQGEVEREGESPAA 1046

Query: 343  SPPQPASPAEEDKMPP--YDEQTQAFIDAAQEARNKFEEAERSLKDMEESIRNLEQE 397
             PP      EE   PP   +E+T+   D  Q       E E   +   E+++  EQ+
Sbjct: 1047 GPPPQELVEEEPSAPPTLLEEETEDGSDKVQPPPETPAEEEMETETEAEALQEKEQD 1103



 Score = 34.7 bits (78), Expect = 0.22
 Identities = 33/127 (25%), Positives = 47/127 (37%), Gaps = 40/127 (31%)

Query: 290 PAPSAPDLTEPKEEQPPVPSSPTEEEEEEEEEEEEEAEEEEEEEDSEEAPPPLSPPQPAS 349
           P P AP  T P    PPVP+                   +EE E+   AP PL PP P  
Sbjct: 808 PPPIAP--TGPPTASPPVPA-------------------KEEPEELPAAPGPLPPPPPPP 846

Query: 350 PAEED--KMPP-----------------YDEQTQAFIDAAQEARNKFEEAERSLKDMEES 390
           P       +PP                  ++ T   I+++ E   + EE E   ++ EE 
Sbjct: 847 PPVPGPVTLPPPQLVPEGTPGGGGPPALEEDLTVININSSDEEEEEEEEEEEEEEEEEEE 906

Query: 391 IRNLEQE 397
             + E+E
Sbjct: 907 EEDFEEE 913


>gi|222418637 golgi autoantigen, golgin subfamily a-like [Homo
           sapiens]
          Length = 750

 Score = 60.8 bits (146), Expect = 3e-09
 Identities = 56/276 (20%), Positives = 121/276 (43%), Gaps = 18/276 (6%)

Query: 122 KERESLQQMAEVTREGFRLKKILIEDWKKAREEKQKKLIELQAGKKSLEDQVEMLRTVKE 181
           K RE  +++ E  ++ +R ++ + E  K   EEK+++  E+   ++ + +Q E+ R  KE
Sbjct: 438 KIREQEEKIREQEKKMWRQEEKIHEQEKIREEEKRQEQEEMWRQEEKIHEQEEIWRQ-KE 496

Query: 182 EAEKPEREAKEQHQKLWEEQLAAAKAQQEQELAADAFKELDDDMDGTVSVTELQTHPELD 241
           +  + E + ++Q +K+W ++    K ++++E   +  +++    +      E+    E  
Sbjct: 497 KMHEQEEKIRKQEEKVWRQE---EKIREQEEKIREQEEKMWRQEEKIREQEEMWREEEKM 553

Query: 242 TDGDGALSEAEAQALLSGDTQTDATSFYDRVWAAIRDKYRSEALPTDLPAPSAPDLTEPK 301
            + +    E + Q               D++W    +K R +            +  E +
Sbjct: 554 HEQEKIWEEEKRQEQ------------EDKMWRQ-EEKIREQEEKVWRQEEKIREQEEKR 600

Query: 302 EEQPPVPSSPTEE-EEEEEEEEEEEAEEEEEEEDSEEAPPPLSPPQPASPAEEDKMPPYD 360
           +EQ        E+  E+EE+ +E+E +  E+EE   E        +     +E+KM   +
Sbjct: 601 QEQEEKMWKQEEKIREQEEKIQEQEEKIREQEEKIREQEEMTQEQEEKMGEQEEKMCEQE 660

Query: 361 EQTQAFIDAAQEARNKFEEAERSLKDMEESIRNLEQ 396
           E+ Q   +       K  E E+ +++ EE IR  E+
Sbjct: 661 EKMQEQEETMWRQEEKIREQEKKIREQEEKIREQEE 696



 Score = 53.1 bits (126), Expect = 6e-07
 Identities = 59/285 (20%), Positives = 129/285 (45%), Gaps = 35/285 (12%)

Query: 117 KEKGRKERESLQQMAEVTREGFRLKKILIEDWK-KAREEKQKKLIELQAGKKSLEDQVEM 175
           +EK R++ E + +  E  RE   L++ + E  K + +EEK+++  +++  +K  E + +M
Sbjct: 376 EEKMRRQEEMMWEKEEKIRE---LEEKMHEQEKIREQEEKRQEEEKIREQEKRQEQEAKM 432

Query: 176 LRTVKEEAEKPEREAKEQHQKLWEEQLAAAKAQQEQELAADAFKELDDDMDGTVSVTELQ 235
            R  +E+  + E + +EQ +K+W ++    K  +++++  +  ++  ++M       E +
Sbjct: 433 WRQ-EEKIREQEEKIREQEKKMWRQE---EKIHEQEKIREEEKRQEQEEMWRQ----EEK 484

Query: 236 THPELDTDGDGALSEAEAQALLSGDTQTDATSFYDRVWAAIRDKYRSEALPTDLPAPSAP 295
            H +          E   Q     + +       ++VW    +K R +            
Sbjct: 485 IHEQ---------EEIWRQKEKMHEQEEKIRKQEEKVWRQ-EEKIREQE----------- 523

Query: 296 DLTEPKEEQPPVPSSPTEEEEEEEEEEEEEAEEEE--EEEDSEEAPPPLSPPQPASPAEE 353
           +    +EE+         E+EE   EEE+  E+E+  EEE  +E    +   +     +E
Sbjct: 524 EKIREQEEKMWRQEEKIREQEEMWREEEKMHEQEKIWEEEKRQEQEDKMWRQEEKIREQE 583

Query: 354 DKMPPYDEQTQAFIDAAQEARNKFEEAERSLKDMEESIRNLEQEI 398
           +K+   +E+ +   +  QE   K  + E  +++ EE I+  E++I
Sbjct: 584 EKVWRQEEKIREQEEKRQEQEEKMWKQEEKIREQEEKIQEQEEKI 628



 Score = 50.8 bits (120), Expect = 3e-06
 Identities = 57/300 (19%), Positives = 129/300 (43%), Gaps = 16/300 (5%)

Query: 113 ENTCKEKGRKERESLQQMAEVTREGFRLKKILIEDWKKAREE--KQKKLI----ELQAGK 166
           E   +E+  K RE  ++M     +    +KI  E+ ++ +EE  +Q++ I    E+   K
Sbjct: 436 EEKIREQEEKIREQEKKMWRQEEKIHEQEKIREEEKRQEQEEMWRQEEKIHEQEEIWRQK 495

Query: 167 KSLEDQVEMLRTVKEEAEKPEREAKEQHQKLWEEQLAAAKAQQEQELAADAFKELDDDMD 226
           + + +Q E +R  +E+  + E + +EQ +K+ E++    + +++     + ++E ++ M 
Sbjct: 496 EKMHEQEEKIRKQEEKVWRQEEKIREQEEKIREQEEKMWRQEEKIREQEEMWRE-EEKMH 554

Query: 227 GTVSVTELQTHPELDTD---GDGALSEAEAQALLSGDT----QTDATSFYDRVWAAIRDK 279
               + E +   E +      +  + E E +     +     +       +++W    +K
Sbjct: 555 EQEKIWEEEKRQEQEDKMWRQEEKIREQEEKVWRQEEKIREQEEKRQEQEEKMWKQ-EEK 613

Query: 280 YRSEALPTDLPAPSAPDLTEPKEEQPPVPSSPTEEEEEEEEEE-EEEAEEEEEEEDSEEA 338
            R +            +  E   EQ  +     E+  E+EE+  E+E + +E+EE     
Sbjct: 614 IREQEEKIQEQEEKIREQEEKIREQEEMTQEQEEKMGEQEEKMCEQEEKMQEQEETMWRQ 673

Query: 339 PPPLSPPQPASPAEEDKMPPYDEQTQAFIDAAQEARNKFEEAERSLKDMEESIRNLEQEI 398
              +   +     +E+K+   +E  Q   +   E   K  E E  +++ EE +R  E+++
Sbjct: 674 EEKIREQEKKIREQEEKIREQEEMMQEQEEKMWEQEEKMCEQEEKMQEQEEKMRRQEEKM 733



 Score = 45.1 bits (105), Expect = 2e-04
 Identities = 49/280 (17%), Positives = 115/280 (41%), Gaps = 33/280 (11%)

Query: 117 KEKGRKERESLQQMAEVTREGFRLKKILIEDWKKAREEKQKKLIELQAGKKSLEDQVEML 176
           +EK  ++ E +Q+  E  +E    ++ + E  +K RE+++K    ++  ++ + ++ E +
Sbjct: 299 EEKMWRQEEKIQEWEEKIQEQ---EEKIREQEEKIREQEEK----MRRQEEMMWEKEEKM 351

Query: 177 RTVKEEAEKPEREAKEQHQKLWEEQLAAAKAQQEQELAADAFKELDDDMDGTVSVTELQT 236
           R  +E   + E + + Q + +WE++    + ++      +  +EL++ M     + E + 
Sbjct: 352 RRQEEMMWEKEEKMRRQEEMMWEKEEKMRRQEEMMWEKEEKIRELEEKMHEQEKIREQEE 411

Query: 237 HPELDTDGDGALSEAEAQALLSGDTQTDATSFYDRVWAAIRDKYRSEALPTDLPAPSAPD 296
             + +          E +A               ++W    +K R +             
Sbjct: 412 KRQEEEKIREQEKRQEQEA---------------KMWRQ-EEKIREQ----------EEK 445

Query: 297 LTEPKEEQPPVPSSPTEEEEEEEEEEEEEAEEEEEEEDSEEAPPPLSPPQPASPAEEDKM 356
           + E +++         E+E+  EEE+ +E EE   +E+       +   +     +E+K+
Sbjct: 446 IREQEKKMWRQEEKIHEQEKIREEEKRQEQEEMWRQEEKIHEQEEIWRQKEKMHEQEEKI 505

Query: 357 PPYDEQTQAFIDAAQEARNKFEEAERSLKDMEESIRNLEQ 396
              +E+     +  +E   K  E E  +   EE IR  E+
Sbjct: 506 RKQEEKVWRQEEKIREQEEKIREQEEKMWRQEEKIREQEE 545



 Score = 36.2 bits (82), Expect = 0.076
 Identities = 26/107 (24%), Positives = 48/107 (44%), Gaps = 5/107 (4%)

Query: 297 LTEPKEEQPPVPSSPTEEEEEEEEEEEEEAEEEEE-----EEDSEEAPPPLSPPQPASPA 351
           L + +EE+        +E EE+ +E+EE+  E+EE     EE        +   +     
Sbjct: 294 LNQQQEEKMWRQEEKIQEWEEKIQEQEEKIREQEEKIREQEEKMRRQEEMMWEKEEKMRR 353

Query: 352 EEDKMPPYDEQTQAFIDAAQEARNKFEEAERSLKDMEESIRNLEQEI 398
           +E+ M   +E+ +   +   E   K    E  + + EE IR LE+++
Sbjct: 354 QEEMMWEKEEKMRRQEEMMWEKEEKMRRQEEMMWEKEEKIRELEEKM 400


>gi|148763347 cell division cycle 2-like 2 isoform 1 [Homo sapiens]
          Length = 780

 Score = 59.3 bits (142), Expect = 8e-09
 Identities = 71/277 (25%), Positives = 112/277 (40%), Gaps = 41/277 (14%)

Query: 117 KEKGRKERESLQQMAEVTREGFRLKKILIEDWKKAREEKQKKLIELQAGKKSLEDQVEML 176
           ++K R+E E  Q+  E+ RE  R ++  +E  ++ RE ++K    ++  +K   +Q E  
Sbjct: 139 QDKARREWER-QKRREMAREHSRRERDRLEQLERKRERERK----MREQQKEQREQKERE 193

Query: 177 RTVKEEAEKPE--REAKEQHQKLWEEQLAAAKAQQEQELAADAFKELDDDMDGTVSVTEL 234
           R  +E  ++ E  RE    H+ + E+     KA           +E  +  DG   V E 
Sbjct: 194 RRAEERRKEREARREVSAHHRTMREDYSDKVKASHWSRSPPRPPRERFELGDGRKPVKE- 252

Query: 235 QTHPELDTDGDGALSEAEAQALLSGDTQTDATSFYDRVWAAIRDKYRSEALPTDLPAPSA 294
                          + E + LLS D Q             I D  R  +      A S 
Sbjct: 253 --------------EKMEERDLLS-DLQD------------ISDSERKTSSAESSSAESG 285

Query: 295 PDLTEPKEEQPPVPSSPTEEEEEEEEEEEEEAEEEEEEEDSEEAPPPLSPPQPASPAEED 354
               E +EE+       +  EE EEEEEEEE EEEE   +SEEA       Q A    E+
Sbjct: 286 SGSEEEEEEEEEEEEEGSTSEESEEEEEEEEEEEEETGSNSEEA-----SEQSAEEVSEE 340

Query: 355 KMPPYDEQTQAFIDAAQEARNKFEEAERSLKDMEESI 391
           +M   DE+ +          ++F+      ++ EE +
Sbjct: 341 EMSE-DEERENENHLLVVPESRFDRDSGESEEAEEEV 376



 Score = 47.8 bits (112), Expect = 3e-05
 Identities = 62/282 (21%), Positives = 107/282 (37%), Gaps = 23/282 (8%)

Query: 180 KEEAEKPEREAKEQHQKLWEEQLAAAKAQQEQELAADAFKELDDDMDGTVSVTELQTHP- 238
           + E  K  RE +++ ++ WE Q     A++      D  ++L+   +    + E Q    
Sbjct: 128 EHERRKRHREEQDKARREWERQKRREMAREHSRRERDRLEQLERKRERERKMREQQKEQR 187

Query: 239 ---ELDTDGDGALSEAEAQALLSGDTQTDATSFYDRVWAA--IRDKYRSEALPTDLPAPS 293
              E +   +    E EA+  +S   +T    + D+V A+   R   R      +L    
Sbjct: 188 EQKERERRAEERRKEREARREVSAHHRTMREDYSDKVKASHWSRSPPRPPRERFELGDGR 247

Query: 294 APDLTEPKEEQP------PVPSSPTEEEEEEEEEEEEEAEEEEEEEDSEEAPPPLSPPQP 347
            P   E  EE+        +  S  +    E    E  +  EEEEE+ EE     S  + 
Sbjct: 248 KPVKEEKMEERDLLSDLQDISDSERKTSSAESSSAESGSGSEEEEEEEEEEEEEGSTSEE 307

Query: 348 ASPAEEDKMPPYDEQTQAFIDAAQEARNKFEEAERSLKDMEESIRNL----EQEISFDFG 403
           +   EE++    +E      +A++++  +  E E S  +  E+  +L    E     D G
Sbjct: 308 SEEEEEEEEEEEEETGSNSEEASEQSAEEVSEEEMSEDEERENENHLLVVPESRFDRDSG 367

Query: 404 PNGEFAYLYS----QCYELTTNEYV---YRLCPFKLVSQKPK 438
            + E          Q   LT  +YV     L P +L  + PK
Sbjct: 368 ESEEAEEEVGEGTPQSSALTEGDYVPDSPALLPIELKQELPK 409



 Score = 30.0 bits (66), Expect = 5.4
 Identities = 31/144 (21%), Positives = 53/144 (36%), Gaps = 6/144 (4%)

Query: 51  VNDDYCDCKDGSDEPGTAACPNGSFHCTNTGYKPLYIPSNRVNDGVCDCCDGTDEYNSGV 110
           + +DY D    S    +   P         G KP+        D + D  D +D      
Sbjct: 216 MREDYSDKVKASHWSRSPPRPPRERFELGDGRKPVKEEKMEERDLLSDLQDISDSERKTS 275

Query: 111 ICENTCKEKGRKERESLQQMAEVTREGFRLKKILIEDWKKAREEKQKKLIELQAGKKSLE 170
             E++  E G    E  ++  E   EG   ++   E+ ++  EE++      +A ++S E
Sbjct: 276 SAESSSAESGSGSEEEEEEEEEEEEEGSTSEESEEEEEEEEEEEEETGSNSEEASEQSAE 335

Query: 171 DQVEMLRTVKEEAEKPEREAKEQH 194
           +  E      EE  + E    E H
Sbjct: 336 EVSE------EEMSEDEERENENH 353


>gi|16332370 cell division cycle 2-like 1 (PITSLRE proteins) isoform
           8 [Homo sapiens]
          Length = 780

 Score = 58.9 bits (141), Expect = 1e-08
 Identities = 73/293 (24%), Positives = 119/293 (40%), Gaps = 35/293 (11%)

Query: 117 KEKGRKERESLQQMAEVTREGFRLKKILIEDWKKAREEKQKKLIELQAGKKSLE------ 170
           K++ RKE++  + + E  RE  R K+   E  K  RE +++K  E+       E      
Sbjct: 101 KDEKRKEKKHAR-VKEKEREHERRKRHREEQDKARREWERQKRREMAREHSRRERGNDGV 159

Query: 171 ----DQVEMLRTVKEEAEKPEREAKEQHQKLWEEQLAAAKAQQEQ---ELAADAFKELDD 223
               D++E L   +E   K   + KEQ ++   E+ A  + ++ +   E++A   + + +
Sbjct: 160 CLFRDRLEQLERKRERERKMREQQKEQREQKERERRAEERRKEREARREVSAH-HRTMRE 218

Query: 224 DMDGTVSVTELQTHP-----ELDTDGDGALSEAEAQALLSGDTQTDATSFYDRVWAAIRD 278
           D    V  +     P     E    GDG     E + +   D  +D           I D
Sbjct: 219 DYSDKVKASHWSRSPPRPPRERFELGDGRKPVKE-EKMEERDLLSDLQD--------ISD 269

Query: 279 KYRSEALPTDLPAPSAPDLTEPKEEQPPVPSSPTEEEEEEEEEEEEEAEEEEEEEDSEEA 338
             R  +      A S     E +EE+       +  EE EEEEEEEE EEEE   +SEEA
Sbjct: 270 SERKTSSAESSSAESGSGSEEEEEEEEEEEEEGSTSEESEEEEEEEEEEEEETGSNSEEA 329

Query: 339 PPPLSPPQPASPAEEDKMPPYDEQTQAFIDAAQEARNKFEEAERSLKDMEESI 391
                  Q A    E++M   DE+ +          ++F+      ++ EE +
Sbjct: 330 -----SEQSAEEVSEEEMSE-DEERENENHLLVVPESRFDRDSGESEEAEEEV 376



 Score = 44.3 bits (103), Expect = 3e-04
 Identities = 69/314 (21%), Positives = 120/314 (38%), Gaps = 28/314 (8%)

Query: 149 KKAREEKQKKLIELQAGKKSLEDQVEMLRTVKEEAEKPERE-AKEQHQKLWEEQLAAAKA 207
           +K  + K+KK     A  K  E + E  +  +EE +K  RE  +++ +++  E     + 
Sbjct: 100 RKDEKRKEKK----HARVKEKEREHERRKRHREEQDKARREWERQKRREMAREHSRRERG 155

Query: 208 QQEQELAADAFKELDDDMDGTVSVTELQTHP----ELDTDGDGALSEAEAQALLSGDTQT 263
                L  D  ++L+   +    + E Q       E +   +    E EA+  +S   +T
Sbjct: 156 NDGVCLFRDRLEQLERKRERERKMREQQKEQREQKERERRAEERRKEREARREVSAHHRT 215

Query: 264 DATSFYDRVWAA--IRDKYRSEALPTDLPAPSAPDLTEPKEEQP------PVPSSPTEEE 315
               + D+V A+   R   R      +L     P   E  EE+        +  S  +  
Sbjct: 216 MREDYSDKVKASHWSRSPPRPPRERFELGDGRKPVKEEKMEERDLLSDLQDISDSERKTS 275

Query: 316 EEEEEEEEEEAEEEEEEEDSEEAPPPLSPPQPASPAEEDKMPPYDEQTQAFIDAAQEARN 375
             E    E  +  EEEEE+ EE     S  + +   EE++    +E      +A++++  
Sbjct: 276 SAESSSAESGSGSEEEEEEEEEEEEEGSTSEESEEEEEEEEEEEEETGSNSEEASEQSAE 335

Query: 376 KFEEAERSLKDMEESIRNL----EQEISFDFGPNGEFAYLYS----QCYELTTNEYV--- 424
           +  E E S  +  E+  +L    E     D G + E          Q   LT  +YV   
Sbjct: 336 EVSEEEMSEDEERENENHLLVVPESRFDRDSGESEEAEEEVGEGTPQSSALTEGDYVPDS 395

Query: 425 YRLCPFKLVSQKPK 438
             L P +L  + PK
Sbjct: 396 PALSPIELKQELPK 409



 Score = 37.4 bits (85), Expect = 0.034
 Identities = 68/318 (21%), Positives = 123/318 (38%), Gaps = 68/318 (21%)

Query: 91  RVNDGVCDCCDGTDEYNSGVICENTCKEKGRKERESLQQMAEVTREGFRLKKILIEDWKK 150
           R NDGVC   D  ++           + K  +ER+  +Q  E   +  R ++   E+ +K
Sbjct: 154 RGNDGVCLFRDRLEQ----------LERKRERERKMREQQKEQREQKERERR--AEERRK 201

Query: 151 AREEKQKKLIELQAGKKSLEDQVEMLRTVKEEAEKPEREAKEQHQKLWEEQLAAAKAQQE 210
            RE +++     +  ++   D+V+        +  P R  +E+ +     +    +  +E
Sbjct: 202 EREARREVSAHHRTMREDYSDKVK----ASHWSRSPPRPPRERFELGDGRKPVKEEKMEE 257

Query: 211 QELAADAFKELDDDMDGTVSVTELQTHPELDTDGDGALSEAEAQALLSGDTQTDATSFYD 270
           ++L +D    L D     +S +E +T            S AE+ +  SG    +      
Sbjct: 258 RDLLSD----LQD-----ISDSERKT------------SSAESSSAESGSGSEEEEE--- 293

Query: 271 RVWAAIRDKYRSEALPTDLPAPSAPDLTEPKEEQPPVPSSPTEEEEEEEEEEEEEAEEEE 330
                  ++   E   T   +    +  E +EE+    S    E+  EE  EEE +E+EE
Sbjct: 294 ------EEEEEEEEGSTSEESEEEEEEEEEEEEETGSNSEEASEQSAEEVSEEEMSEDEE 347

Query: 331 EEE-----------------DSEEAPPPL--SPPQPASPAEEDKMPPYDEQTQAFIDAAQ 371
            E                  +SEEA   +    PQ ++  E D +P  D    + I+  Q
Sbjct: 348 RENENHLLVVPESRFDRDSGESEEAEEEVGEGTPQSSALTEGDYVP--DSPALSPIELKQ 405

Query: 372 EARNKFEEAERSLKDMEE 389
           E   K+  A +  + +EE
Sbjct: 406 EL-PKYLPALQGCRSVEE 422



 Score = 30.0 bits (66), Expect = 5.4
 Identities = 31/144 (21%), Positives = 53/144 (36%), Gaps = 6/144 (4%)

Query: 51  VNDDYCDCKDGSDEPGTAACPNGSFHCTNTGYKPLYIPSNRVNDGVCDCCDGTDEYNSGV 110
           + +DY D    S    +   P         G KP+        D + D  D +D      
Sbjct: 216 MREDYSDKVKASHWSRSPPRPPRERFELGDGRKPVKEEKMEERDLLSDLQDISDSERKTS 275

Query: 111 ICENTCKEKGRKERESLQQMAEVTREGFRLKKILIEDWKKAREEKQKKLIELQAGKKSLE 170
             E++  E G    E  ++  E   EG   ++   E+ ++  EE++      +A ++S E
Sbjct: 276 SAESSSAESGSGSEEEEEEEEEEEEEGSTSEESEEEEEEEEEEEEETGSNSEEASEQSAE 335

Query: 171 DQVEMLRTVKEEAEKPEREAKEQH 194
           +  E      EE  + E    E H
Sbjct: 336 EVSE------EEMSEDEERENENH 353


>gi|239745089 PREDICTED: golgi autoantigen, golgin subfamily a-like
           [Homo sapiens]
          Length = 828

 Score = 58.2 bits (139), Expect = 2e-08
 Identities = 60/281 (21%), Positives = 117/281 (41%), Gaps = 20/281 (7%)

Query: 117 KEKGRKERESLQQMAEVTREGFRLKKILIEDWKKAREEKQKKLIELQAGKKSLEDQVEML 176
           KE+  +E+E + +  E  +E  R++    E  KK REE++    + +  +K  E+  E  
Sbjct: 371 KEERMREQEKMWEQEEKMQEEERIR----EREKKMREEEETMREQEEKMQKQEENMWE-- 424

Query: 177 RTVKEEAEKPEREAKEQHQKLWEEQLAAAKAQQEQELAADAFKELDDDMDGTVSVTELQT 236
              +EE E  ++   EQ +KLWE++    K Q+++E   +  +++ D  +      ++  
Sbjct: 425 ---QEEKEWQQQRLPEQKEKLWEQE----KMQEQEEKIWEQEEKIRDQEEMWGQEKKMWR 477

Query: 237 HPELDTDGDGALSEAEAQALLSGDTQTDATSFYDRVWAAIRDKYRSEALPTDLPAPSAPD 296
             ++    D    + E       D +       +R+W         E    +       +
Sbjct: 478 QEKMREQEDQMWEQEEKMR----DQEQKMWDQEERMWEQDERLREKEERMREQKKMWQQE 533

Query: 297 LTEPKEEQPPVPSSPTEEEEEEEEEEEEEAEEEEEEEDSEEAPPPLSPPQPASPAEEDKM 356
               +E++       T ++EE+  EEE   E E++  + EE    +   +     +E+KM
Sbjct: 534 EKMREEKKTQEQEKKTWDQEEKMREEERMREREKKMREEEEM---MREQEEKMQEQEEKM 590

Query: 357 PPYDEQTQAFIDAAQEARNKFEEAERSLKDMEESIRNLEQE 397
              +E+     +  QE   K  E E  + + EE  +  EQE
Sbjct: 591 REQEEKMWEQEEKMQEQEEKMWEQEEKMWEQEEEDKMQEQE 631



 Score = 53.1 bits (126), Expect = 6e-07
 Identities = 56/304 (18%), Positives = 128/304 (42%), Gaps = 22/304 (7%)

Query: 113 ENTCKEKGRKERESLQQMAEVTREGFRLKKILIE----DWKKAREEKQKKLIELQAGKKS 168
           E   +E+ +K RE  + M E   +  + ++ + E    +W++ R  +QK+ +  Q   + 
Sbjct: 391 EERIREREKKMREEEETMREQEEKMQKQEENMWEQEEKEWQQQRLPEQKEKLWEQEKMQE 450

Query: 169 LEDQVEMLRTVKEEAEKPEREAKEQHQKLWEEQLAAAKAQQ---EQELAADAFKELDDDM 225
            E+++      +EE  + + E   Q +K+W ++    +  Q   ++E   D  +++ D  
Sbjct: 451 QEEKI----WEQEEKIRDQEEMWGQEKKMWRQEKMREQEDQMWEQEEKMRDQEQKMWDQE 506

Query: 226 DGTVSVTELQTHPELDTDGDGALSEAEAQALLSGDTQTDATSFYD-----RVWAAIRDKY 280
           +      E     E        + + E +      TQ      +D     R    +R++ 
Sbjct: 507 ERMWEQDERLREKEERMREQKKMWQQEEKMREEKKTQEQEKKTWDQEEKMREEERMRERE 566

Query: 281 RSEALPTDLPAPSAPDLTEPKEEQPPVPSSPTEEEEEEEEEEE------EEAEEEEEEED 334
           +      ++       + E +E+         E+EE+ +E+EE      E+  E+EEE+ 
Sbjct: 567 KKMREEEEMMREQEEKMQEQEEKMREQEEKMWEQEEKMQEQEEKMWEQEEKMWEQEEEDK 626

Query: 335 SEEAPPPLSPPQPASPAEEDKMPPYDEQTQAFIDAAQEARNKFEEAERSLKDMEESIRNL 394
            +E    +   +     +E+KM   +E+ +   +  +E   K +  E  +++ EE ++  
Sbjct: 627 MQEQEEMMWEQEEKMQEQEEKMWEQEEKMREQEEKMREQEEKMQGQEEKMREQEEKMQGQ 686

Query: 395 EQEI 398
           E+++
Sbjct: 687 EEKM 690



 Score = 50.1 bits (118), Expect = 5e-06
 Identities = 65/304 (21%), Positives = 133/304 (43%), Gaps = 50/304 (16%)

Query: 114 NTCKEKGRKERESLQQMAEVTREG----FRLKKILIEDWKKAREEKQKKLIE---LQAGK 166
           NT +E+  ++ E L++  +  R+     +R ++ L E   K RE+++K   +   L+  +
Sbjct: 230 NTLQEEMWRQEEELREQEKKIRKQEEKMWRQEERLREQEGKMREQEEKMRRQEKRLREQE 289

Query: 167 KSLEDQVEMLRTVKEEAEKPEREAKEQHQKLWEEQLAAAKAQQEQELAADAFKELDDDMD 226
           K L +Q + LR  K+  E+ E + +EQ +K+WE++      +QE+++     +  + +  
Sbjct: 290 KELREQEKELREQKKLREQ-EEQMQEQEEKMWEQE--EKMREQEEKMWRQEERLWEQEKQ 346

Query: 227 GTVSVTELQTHPELDTDGDGALSEAEAQALLSGDTQTDATSFYDRVWAAIRDKYRSEALP 286
                 +++   E   + D  L E E           +     +++W    +K + E   
Sbjct: 347 MREQEQKMRDQEERMWEQDERLREKE-----------ERMREQEKMWEQ-EEKMQEE--- 391

Query: 287 TDLPAPSAPDLTEPKEEQPPVPSSPTEEEEEEEEEEEEEAEEEEEEEDSEEAPPPLSPPQ 346
                    +    +E++         E+EE+ +++EE   E+EE+E  ++      P Q
Sbjct: 392 ---------ERIREREKKMREEEETMREQEEKMQKQEENMWEQEEKEWQQQR----LPEQ 438

Query: 347 PASPAEEDKMPPYD----EQTQAFIDA----AQEAR----NKFEEAERSLKDMEESIRNL 394
                E++KM   +    EQ +   D      QE +     K  E E  + + EE +R+ 
Sbjct: 439 KEKLWEQEKMQEQEEKIWEQEEKIRDQEEMWGQEKKMWRQEKMREQEDQMWEQEEKMRDQ 498

Query: 395 EQEI 398
           EQ++
Sbjct: 499 EQKM 502



 Score = 50.1 bits (118), Expect = 5e-06
 Identities = 56/292 (19%), Positives = 122/292 (41%), Gaps = 16/292 (5%)

Query: 113 ENTCKEKGRKERESLQQMAEVTREGFRLKKILIEDWKKAREEKQKKLIELQAGKKSLEDQ 172
           E   +E+  K  E  ++M E   + +R ++ L E  K+ RE++QK    ++  ++ + +Q
Sbjct: 309 EEQMQEQEEKMWEQEEKMREQEEKMWRQEERLWEQEKQMREQEQK----MRDQEERMWEQ 364

Query: 173 VEMLRTVKEEAEKPEREAKEQHQKLWEEQL---AAAKAQQEQELAADAFKELDDDMDGTV 229
            E LR  KEE  + + +  EQ +K+ EE+       K ++E+E   +  +++    +   
Sbjct: 365 DERLRE-KEERMREQEKMWEQEEKMQEEERIREREKKMREEEETMREQEEKMQKQEENMW 423

Query: 230 SVTELQTHPELDTDGDGALSEAEAQALLSGD--TQTDATSFYDRVWAAIRDKYRSEALPT 287
              E +   +   +    L E E           Q +     + +W   +  +R E +  
Sbjct: 424 EQEEKEWQQQRLPEQKEKLWEQEKMQEQEEKIWEQEEKIRDQEEMWGQEKKMWRQEKM-- 481

Query: 288 DLPAPSAPDLTEPKEEQPPVPSSPTEEEEEEEEEEEEEAEEEEEEEDSEEAPPPLSPPQP 347
                    + E +E+         ++EE   E++E   E+EE   + ++        + 
Sbjct: 482 ---REQEDQMWEQEEKMRDQEQKMWDQEERMWEQDERLREKEERMREQKKMWQQEEKMRE 538

Query: 348 ASPAEEDKMPPYD-EQTQAFIDAAQEARNKFEEAERSLKDMEESIRNLEQEI 398
               +E +   +D E+     +  +E   K  E E  +++ EE ++  E+++
Sbjct: 539 EKKTQEQEKKTWDQEEKMREEERMREREKKMREEEEMMREQEEKMQEQEEKM 590



 Score = 48.9 bits (115), Expect = 1e-05
 Identities = 61/313 (19%), Positives = 123/313 (39%), Gaps = 51/313 (16%)

Query: 117 KEKGRKERESLQQMAEVTREGFRLKKILIEDWKKAREEKQKKLIELQAGKKSLEDQVEM- 175
           +EK +K+ E++ +  E   +  RL +   + W++ + ++Q++ I  Q  K  + DQ EM 
Sbjct: 412 EEKMQKQEENMWEQEEKEWQQQRLPEQKEKLWEQEKMQEQEEKIWEQEEK--IRDQEEMW 469

Query: 176 -----------LRTVKEEAEKPEREAKEQHQKLW----------------EEQLAAAKAQ 208
                      +R  +++  + E + ++Q QK+W                EE++   K  
Sbjct: 470 GQEKKMWRQEKMREQEDQMWEQEEKMRDQEQKMWDQEERMWEQDERLREKEERMREQKKM 529

Query: 209 QEQELAADAFKELDDDMDGTVSVTELQTHPELDTDGDGALSEAEAQALLSGDTQTDATSF 268
            +QE      K+  +    T    E     E   + +  + E E       +   +    
Sbjct: 530 WQQEEKMREEKKTQEQEKKTWDQEEKMREEERMREREKKMREEEEMMREQEEKMQEQ--- 586

Query: 269 YDRVWAAIRDKYRSEALPTDLPAPSAPDLTEPKEEQPPVPSSPTEEEEEEEEEE---EEE 325
                    +K R +            +  E   EQ        EE++ +E+EE   E+E
Sbjct: 587 --------EEKMREQEEKMWEQEEKMQEQEEKMWEQEEKMWEQEEEDKMQEQEEMMWEQE 638

Query: 326 AEEEEEEEDSEEAPPPLSPPQPASPAEEDKMPPYDEQTQAFIDAAQEARNKFEEAERSLK 385
            + +E+EE   E    +         +E+KM   +E+ Q   +  +E   K +  E  ++
Sbjct: 639 EKMQEQEEKMWEQEEKMR-------EQEEKMREQEEKMQGQEEKMREQEEKMQGQEEKMR 691

Query: 386 DMEESIRNLEQEI 398
           + EE +R  E+++
Sbjct: 692 EQEEKMRGQEEKM 704



 Score = 47.8 bits (112), Expect = 3e-05
 Identities = 63/289 (21%), Positives = 122/289 (42%), Gaps = 44/289 (15%)

Query: 124 RESLQQMAEVTREGFRLKKILIEDWKKAREEKQKKLIELQAGKKSLEDQVEMLRTVKEEA 183
           RE   +M E   +  R +K L E  K+ RE+ +K+L E    +K L +Q E ++  +E+ 
Sbjct: 265 REQEGKMREQEEKMRRQEKRLREQEKELREQ-EKELRE----QKKLREQEEQMQEQEEKM 319

Query: 184 EKPEREAKEQHQKLW--EEQLAAAKAQ---QEQELAADAFKELDDD-----MDGTVSVTE 233
            + E + +EQ +K+W  EE+L   + Q   QEQ++     +  + D      +  +   E
Sbjct: 320 WEQEEKMREQEEKMWRQEERLWEQEKQMREQEQKMRDQEERMWEQDERLREKEERMREQE 379

Query: 234 LQTHPELDTDGDGALSEAEAQALLSGDTQTDATSFY----DRVWAAIRDKYRSEALPTDL 289
                E     +  + E E +     +T  +         + +W     +++ + LP   
Sbjct: 380 KMWEQEEKMQEEERIREREKKMREEEETMREQEEKMQKQEENMWEQEEKEWQQQRLP--- 436

Query: 290 PAPSAPDLTEPKEEQPPVPSSPTEEEEEEEEEEEEEAEEEEEEEDSEEAPPPLSPPQPAS 349
                    E KE+          E+E+ +E+EE+  E+EE+  D EE        Q   
Sbjct: 437 ---------EQKEK--------LWEQEKMQEQEEKIWEQEEKIRDQEE-----MWGQEKK 474

Query: 350 PAEEDKMPPYDEQTQAFIDAAQEARNKFEEAERSLKDMEESIRNLEQEI 398
              ++KM   ++Q     +  ++   K  + E  + + +E +R  E+ +
Sbjct: 475 MWRQEKMREQEDQMWEQEEKMRDQEQKMWDQEERMWEQDERLREKEERM 523



 Score = 30.8 bits (68), Expect = 3.2
 Identities = 21/92 (22%), Positives = 40/92 (43%), Gaps = 16/92 (17%)

Query: 307 VPSSPTEEEEEEEEEEEEEAEEEEEEEDSEEAPPPLSPPQPASPAEEDKMPPYDEQTQAF 366
           +P   T   +EE   +EEE  E+E++                   +E+KM   +E+ +  
Sbjct: 224 LPQVQTNTLQEEMWRQEEELREQEKK----------------IRKQEEKMWRQEERLREQ 267

Query: 367 IDAAQEARNKFEEAERSLKDMEESIRNLEQEI 398
               +E   K    E+ L++ E+ +R  E+E+
Sbjct: 268 EGKMREQEEKMRRQEKRLREQEKELREQEKEL 299


>gi|17975763 myelin transcription factor 1 [Homo sapiens]
          Length = 1121

 Score = 57.4 bits (137), Expect = 3e-08
 Identities = 30/59 (50%), Positives = 35/59 (59%)

Query: 299 EPKEEQPPVPSSPTEEEEEEEEEEEEEAEEEEEEEDSEEAPPPLSPPQPASPAEEDKMP 357
           E +EE+        EEEEEEEEEEEEE EEEEEEE+ EEA P +   +  S     K P
Sbjct: 268 EEEEEEDEEEEEEEEEEEEEEEEEEEEEEEEEEEEEEEEAAPDVIFQEDTSHTSAQKAP 326



 Score = 53.1 bits (126), Expect = 6e-07
 Identities = 27/49 (55%), Positives = 31/49 (63%)

Query: 296 DLTEPKEEQPPVPSSPTEEEEEEEEEEEEEAEEEEEEEDSEEAPPPLSP 344
           D  E +EE+        EEEEEEEEEEEEE EEEEEEE+ EE     +P
Sbjct: 261 DEEEEEEEEEEEEDEEEEEEEEEEEEEEEEEEEEEEEEEEEEEEEEAAP 309



 Score = 50.4 bits (119), Expect = 4e-06
 Identities = 25/52 (48%), Positives = 32/52 (61%)

Query: 299 EPKEEQPPVPSSPTEEEEEEEEEEEEEAEEEEEEEDSEEAPPPLSPPQPASP 350
           E ++E+        EE+EEEEEEEEEE EEEEEEE+ EE        + A+P
Sbjct: 258 EEEDEEEEEEEEEEEEDEEEEEEEEEEEEEEEEEEEEEEEEEEEEEEEEAAP 309



 Score = 50.4 bits (119), Expect = 4e-06
 Identities = 27/56 (48%), Positives = 32/56 (57%)

Query: 299 EPKEEQPPVPSSPTEEEEEEEEEEEEEAEEEEEEEDSEEAPPPLSPPQPASPAEED 354
           + +EE+        EEEEEEEEEEEEE EEEEEEE+ EE         P    +ED
Sbjct: 261 DEEEEEEEEEEEEDEEEEEEEEEEEEEEEEEEEEEEEEEEEEEEEEAAPDVIFQED 316



 Score = 50.4 bits (119), Expect = 4e-06
 Identities = 28/61 (45%), Positives = 34/61 (55%)

Query: 313 EEEEEEEEEEEEEAEEEEEEEDSEEAPPPLSPPQPASPAEEDKMPPYDEQTQAFIDAAQE 372
           EEEEEEEEE+EEE EEEEEEE+ EE        +     EE+  P    Q      +AQ+
Sbjct: 265 EEEEEEEEEDEEEEEEEEEEEEEEEEEEEEEEEEEEEEEEEEAAPDVIFQEDTSHTSAQK 324

Query: 373 A 373
           A
Sbjct: 325 A 325



 Score = 50.1 bits (118), Expect = 5e-06
 Identities = 29/86 (33%), Positives = 45/86 (52%), Gaps = 5/86 (5%)

Query: 298 TEPKEEQPPVPSSPTEEEEEEEEEEEEEAEEEEEEEDSEEAPPPLSPPQPASPAEEDKMP 357
           +E   +Q  + S   E+EEEEEEEEEEE +EEEEEE+ EE        +     EE++  
Sbjct: 245 SEESSKQKGILSHEEEDEEEEEEEEEEEEDEEEEEEEEEE-----EEEEEEEEEEEEEEE 299

Query: 358 PYDEQTQAFIDAAQEARNKFEEAERS 383
             +E+ +A  D   +       A+++
Sbjct: 300 EEEEEEEAAPDVIFQEDTSHTSAQKA 325



 Score = 43.1 bits (100), Expect = 6e-04
 Identities = 25/60 (41%), Positives = 31/60 (51%), Gaps = 5/60 (8%)

Query: 299 EPKEEQPPVPSSPTEEEEEEEEEEEEEAE-----EEEEEEDSEEAPPPLSPPQPASPAEE 353
           E +EE+        EEEEEEEEEEEEEA      +E+    S +  P L  P+  SP  E
Sbjct: 280 EEEEEEEEEEEEEEEEEEEEEEEEEEEAAPDVIFQEDTSHTSAQKAPELRGPESPSPKPE 339



 Score = 40.4 bits (93), Expect = 0.004
 Identities = 36/133 (27%), Positives = 61/133 (45%), Gaps = 12/133 (9%)

Query: 113 ENTCKEKGRK----ERESLQQMAEVTREGFR-LKKILIEDWKKAREEKQKKLIELQAGKK 167
           E    E+G K    + E  +++ EVT E  + L    +ED       KQK ++  +   +
Sbjct: 203 EGAASEEGEKGLFIQPEDAEEVVEVTTERSQDLCPQSLEDAASEESSKQKGILSHEEEDE 262

Query: 168 SLEDQVEMLRTVKEEAEKPEREAKEQHQKLWEEQLAAAKAQQEQELAADAFKELDDDMDG 227
             E++ E     +EE E+ E E +E+ ++  EE+    + ++E+E A D   + D     
Sbjct: 263 EEEEEEEEEEEDEEEEEEEEEEEEEEEEE-EEEEEEEEEEEEEEEAAPDVIFQED----- 316

Query: 228 TVSVTELQTHPEL 240
             S T  Q  PEL
Sbjct: 317 -TSHTSAQKAPEL 328



 Score = 30.8 bits (68), Expect = 3.2
 Identities = 21/90 (23%), Positives = 39/90 (43%), Gaps = 7/90 (7%)

Query: 298 TEPKEEQPPVPSSPTEEEEEEEEEEEEEAEEEEEEEDSEEAPPPLSPPQPASPAEEDKMP 357
           TE  ++  P        EE  +++     EEE+EEE+ EE        +     EE++  
Sbjct: 229 TERSQDLCPQSLEDAASEESSKQKGILSHEEEDEEEEEEE-------EEEEEDEEEEEEE 281

Query: 358 PYDEQTQAFIDAAQEARNKFEEAERSLKDM 387
             +E+ +   +  +E   + EE E +  D+
Sbjct: 282 EEEEEEEEEEEEEEEEEEEEEEEEEAAPDV 311


>gi|100816397 MYST histone acetyltransferase (monocytic leukemia) 4
            [Homo sapiens]
          Length = 2073

 Score = 57.4 bits (137), Expect = 3e-08
 Identities = 27/49 (55%), Positives = 35/49 (71%)

Query: 298  TEPKEEQPPVPSSPTEEEEEEEEEEEEEAEEEEEEEDSEEAPPPLSPPQ 346
            +E +EE+        EEEEEE+EEEEEE EEEEEEE+ + +PP L+ PQ
Sbjct: 1069 SEEEEEEEDEEEEEEEEEEEEDEEEEEEEEEEEEEENIQSSPPRLTKPQ 1117



 Score = 52.8 bits (125), Expect = 8e-07
 Identities = 40/111 (36%), Positives = 57/111 (51%), Gaps = 6/111 (5%)

Query: 250  EAEAQALLSGDTQTDATSFYDRVWAAIRDKYRSEALPTDLPAPSAPDLTEPKEEQPPVPS 309
            E E Q +LS  T+ ++     +V +  +  +  E+ P         +L++   E+     
Sbjct: 1019 EKEEQEILS--TRANSRQSPAKVQSKNKYLHSPESRPVTGERGQLLELSKESSEEEE-EE 1075

Query: 310  SPTEEEEEEEEEEEEEAEEEEEEEDSEEAPPPLSPP---QPASPAEEDKMP 357
               EEEEEEEEEEE+E EEEEEEE+ EE     SPP   +P S A + K P
Sbjct: 1076 EDEEEEEEEEEEEEDEEEEEEEEEEEEEENIQSSPPRLTKPQSVAIKRKRP 1126



 Score = 50.1 bits (118), Expect = 5e-06
 Identities = 47/153 (30%), Positives = 65/153 (42%), Gaps = 15/153 (9%)

Query: 234  LQTHPELDTDGDGALSEAEAQALLSGDTQTDATSFYDRVWAAIRDKYRSEAL-------P 286
            L T PE   + D  ++  E +    G T        + V      K   EAL        
Sbjct: 1273 LYTPPETPMEPDEQVTVEEQKETSEGKTSPSPIRIEEEV------KETGEALLPQEENRR 1326

Query: 287  TDLPAPSAPDLTEPKEEQPPVPSSPTEEEEEEEEEEEEEAEEEEEEEDSEEAPPPLSPPQ 346
             +  AP +P+ T P E+       P EEEEEEEEEEEEE EEEE EE+         P  
Sbjct: 1327 EETCAPVSPN-TSPGEKPEDDLIKP-EEEEEEEEEEEEEEEEEEGEEEEGGGNVEKDPDG 1384

Query: 347  PASPAEEDKMPPYDEQTQAFIDAAQEARNKFEE 379
              S  +E+     +++  A +D  +E   + EE
Sbjct: 1385 AKSQEKEEPEISTEKEDSARLDDHEEEEEEDEE 1417



 Score = 41.6 bits (96), Expect = 0.002
 Identities = 36/117 (30%), Positives = 51/117 (43%), Gaps = 12/117 (10%)

Query: 285  LPTDLPAPSAPDLTEPKEEQPPVP---SSPTEEEEEEEEEEEEEAEEEEEEEDSEEAPPP 341
            L T    P  PD     EEQ       +SP+    EEE +E  EA   +EE   EE   P
Sbjct: 1273 LYTPPETPMEPDEQVTVEEQKETSEGKTSPSPIRIEEEVKETGEALLPQEENRREETCAP 1332

Query: 342  LSP-PQPASPAEEDKMPPYDEQTQAFIDAAQEARNKFEEAERSLKDMEESIRNLEQE 397
            +SP   P    E+D + P +E+        +E   + EE E    + EE   N+E++
Sbjct: 1333 VSPNTSPGEKPEDDLIKPEEEE--------EEEEEEEEEEEEEEGEEEEGGGNVEKD 1381



 Score = 41.6 bits (96), Expect = 0.002
 Identities = 37/120 (30%), Positives = 50/120 (41%), Gaps = 21/120 (17%)

Query: 296  DLTEPKEEQPPVPSSPTEEEEEEEEEEEEEAE---------------EEEEEEDSEEAPP 340
            DL +P+EE+        EEEEEEEEEE EE E               E+EE E S E   
Sbjct: 1346 DLIKPEEEE----EEEEEEEEEEEEEEGEEEEGGGNVEKDPDGAKSQEKEEPEISTEKED 1401

Query: 341  PLSPPQPASPAEEDKMPPYDEQTQAFIDAAQEARNKFEEAERSLKDMEESIRNLEQEISF 400
                       EED+ P ++E   A  D   ++  +  E E+     E     LE + +F
Sbjct: 1402 SARLDDHEEEEEEDEEPSHNEDHDA--DDEDDSHMESAEVEKEELPRESFKEVLENQETF 1459



 Score = 36.6 bits (83), Expect = 0.058
 Identities = 32/123 (26%), Positives = 51/123 (41%), Gaps = 10/123 (8%)

Query: 245  DGALSEAEAQALLSGDTQTDATSFYDRVWAAIRDKYRSEALPTDLPAPSAPDLTEPKEEQ 304
            + A+SE E +A    +   +  S ++        K   E L T   +  +P   + K + 
Sbjct: 994  NAAVSEEEREAEKEAERLMEQASCWE--------KEEQEILSTRANSRQSPAKVQSKNKY 1045

Query: 305  PPVPSSP--TEEEEEEEEEEEEEAEEEEEEEDSEEAPPPLSPPQPASPAEEDKMPPYDEQ 362
               P S   T E  +  E  +E +EEEEEEED EE        +     EE++    +E 
Sbjct: 1046 LHSPESRPVTGERGQLLELSKESSEEEEEEEDEEEEEEEEEEEEDEEEEEEEEEEEEEEN 1105

Query: 363  TQA 365
             Q+
Sbjct: 1106 IQS 1108



 Score = 35.0 bits (79), Expect = 0.17
 Identities = 48/254 (18%), Positives = 99/254 (38%), Gaps = 25/254 (9%)

Query: 165  GKKSLEDQVEMLRTVKEEAEKPEREAKEQHQKLWEEQLAAAKAQQEQELAADAFKELDDD 224
            G+K  +D ++     +EE E+ E E +E+ ++  EE+      +++ + A    KE  + 
Sbjct: 1340 GEKPEDDLIKP----EEEEEEEEEEEEEEEEEEGEEEEGGGNVEKDPDGAKSQEKEEPEI 1395

Query: 225  MDGTVSVTELQTHPELDTDGDGALSEAEAQALLSGDTQTDATSF--YDRVWAAIRDKYRS 282
                     L  H E + + +      +  A    D+  ++      +    + ++   +
Sbjct: 1396 STEKEDSARLDDHEEEEEEDEEPSHNEDHDADDEDDSHMESAEVEKEELPRESFKEVLEN 1455

Query: 283  EALPTDL---PAPSAP--------DLTEPKEEQP-PVPSSPTEEEEEEEEEEEEEAEEEE 330
            +    DL   P  S P        DLT     +P  +   P    E +EE    E  +++
Sbjct: 1456 QETFLDLNVQPGHSNPEVLMDCGVDLTASCNSEPKELAGDPEAVPESDEEPPPGEQAQKQ 1515

Query: 331  EEEDSEEAPPPLSPPQPASPAEEDKMPPYDEQTQAFIDAAQEARNKFEEAERSLKDMEES 390
            ++++S+E         PA+      M    E  QA     QE+  + ++  +   + +E+
Sbjct: 1516 DQKNSKEVDTEFKEGNPAT------MEIDSETVQAVQSLTQESSEQ-DDTFQDCAETQEA 1568

Query: 391  IRNLEQEISFDFGP 404
             R+L+     D  P
Sbjct: 1569 CRSLQNYTRADQSP 1582


>gi|117414137 retinitis pigmentosa 1-like 1 [Homo sapiens]
          Length = 2400

 Score = 57.4 bits (137), Expect = 3e-08
 Identities = 55/241 (22%), Positives = 104/241 (43%), Gaps = 12/241 (4%)

Query: 150  KAREEKQKKLIELQAGKKSLEDQVEMLRTVKEEAEKPEREAKEQHQKLWEEQLAAAKAQQ 209
            + + + + ++IE Q  ++  + + E +  ++ E E  E E + Q +    E + A +A+ 
Sbjct: 1951 EGQTQPESEVIESQEAEEEAQPESEDVEALEVEVETQEAEGEAQPES---EDVEAPEAEG 2007

Query: 210  EQELAADAFKELDDDMDGTVSVTELQTHPELDTDGDGALSEAEAQALLSGDTQTDATSFY 269
            E +   +A +E   + DG  +  + +     + +G+   +E +AQ    G    +A    
Sbjct: 2008 EMQ---EAEEEAQPESDGVEAQPKSEGEEAQEVEGETQKTEGDAQPESDGVEAPEAEEEA 2064

Query: 270  DRVWAAIRDKYRSEALPT--DLPAPSAPDLTEPKEEQPPVPSSPTEEEEEEEEEEEEEAE 327
                  +++    EA P   D+ A  A    +P+ E    P +  E ++ E  E  E   
Sbjct: 2065 QEAEGEVQEA-EGEAHPESEDVDAQEAEGEAQPESEGVEAPEAEGEAQKAEGIEAPETEG 2123

Query: 328  EEEEEEDSEEAPPPLSPPQPASPAEEDKMPPYDEQTQAFIDAAQEARNKFEEAERSLKDM 387
            E + E +  EAP      QP S   E +    + Q ++    AQEA    EEA+  L+ +
Sbjct: 2124 EAQPESEGIEAPEAEGEAQPESEGVEAQDAEGEAQPESEGIEAQEAE---EEAQPELEGV 2180

Query: 388  E 388
            E
Sbjct: 2181 E 2181



 Score = 52.0 bits (123), Expect = 1e-06
 Identities = 52/212 (24%), Positives = 83/212 (39%), Gaps = 12/212 (5%)

Query: 181  EEAEKPEREAKEQHQKLWEEQLAAAKAQQEQELAADAFKELDDDMDGTVSVTELQTHPEL 240
            E+ E PE E + Q +    E   A    Q +   A+A +   +    T SV  L+T  E 
Sbjct: 1872 EDVEAPEAEGEAQPESEDVETPEAEWEVQPESEGAEAPEAEKEAQPETESVEALETEGED 1931

Query: 241  DTDGDGALSEAEAQALLSGDTQTDATSFYDRVWAAIRDKYRS----EALPTDLPAPSAPD 296
            + + +GA ++   +A    + QT   S       A  +        EAL  ++    A  
Sbjct: 1932 EPESEGAEAQEAEEAAQEAEGQTQPESEVIESQEAEEEAQPESEDVEALEVEVETQEAEG 1991

Query: 297  LTEPKEEQPPVPSSPTEEEEEEEEEEEEEAEEEEEEEDSEEAPPPLSPPQPASPAEEDKM 356
              +P+ E    P        E E E +E  EE + E D  EA P     +      E + 
Sbjct: 1992 EAQPESEDVEAP--------EAEGEMQEAEEEAQPESDGVEAQPKSEGEEAQEVEGETQK 2043

Query: 357  PPYDEQTQAFIDAAQEARNKFEEAERSLKDME 388
               D Q ++    A EA  + +EAE  +++ E
Sbjct: 2044 TEGDAQPESDGVEAPEAEEEAQEAEGEVQEAE 2075



 Score = 43.5 bits (101), Expect = 5e-04
 Identities = 32/116 (27%), Positives = 47/116 (40%), Gaps = 9/116 (7%)

Query: 292  PSAPDLTEPKEEQPPVPSSPTEEEEEEEEEEEEEAEEEEEEEDSEEAPPPLSPPQPASPA 351
            P + D+  P+ E    P S   E  E E E + E+E  E  E  +EA P     +     
Sbjct: 1869 PESEDVEAPEAEGEAQPESEDVETPEAEWEVQPESEGAEAPEAEKEAQPETESVEALETE 1928

Query: 352  EEDKMPPYDEQTQAFIDAAQEARN---------KFEEAERSLKDMEESIRNLEQEI 398
             ED+      + Q   +AAQEA           + +EAE   +   E +  LE E+
Sbjct: 1929 GEDEPESEGAEAQEAEEAAQEAEGQTQPESEVIESQEAEEEAQPESEDVEALEVEV 1984



 Score = 43.1 bits (100), Expect = 6e-04
 Identities = 63/282 (22%), Positives = 104/282 (36%), Gaps = 12/282 (4%)

Query: 146  EDWKKAREEKQKKLIELQAGKKSLE--DQVEMLRTVKEEAEKPEREAKEQHQKLWEEQLA 203
            E+ ++   E QK   + Q     +E  +  E  +  + E ++ E EA  + + + + Q A
Sbjct: 2032 EEAQEVEGETQKTEGDAQPESDGVEAPEAEEEAQEAEGEVQEAEGEAHPESEDV-DAQEA 2090

Query: 204  AAKAQQEQELAADAFKELDDDMDGTVSVTELQTHPELDTDG-DGALSEAEAQALLSGDTQ 262
              +AQ E E       E +      +   E +   + +++G +   +E EAQ    G   
Sbjct: 2091 EGEAQPESEGVEAPEAEGEAQKAEGIEAPETEGEAQPESEGIEAPEAEGEAQPESEGVEA 2150

Query: 263  TDATSFYDRVWAAIRDKYRSEALPTDLPAPSAPDL---TEPKEEQPPVPSSPTEEEEEEE 319
             DA          I  +   E    +L    AP+     +P+ E    P +  E + E E
Sbjct: 2151 QDAEGEAQPESEGIEAQEAEEEAQPELEGVEAPEAEGEAQPESEGIEAPEAEGEAQPELE 2210

Query: 320  EEEEEEAEEE-EEEEDSEEAPPPLSPPQPASPAE---EDKMPPYDEQTQAFIDAAQEARN 375
              E  EAEEE + E +  E P      QP S  E   E K  P         + A E+ +
Sbjct: 2211 GVEAPEAEEEAQPEPEGVETPEAEGEAQPESEGETQGEKKGSPQVSLGDGQSEEASESSS 2270

Query: 376  KFEEAERSLKDMEESIRNLEQEISFDFGPNGEFAYLYSQCYE 417
               E +R             Q      GP+   A  +  C++
Sbjct: 2271 PVPE-DRPTPPPSPGGDTPHQRPGSQTGPSSSRASSWGNCWQ 2311



 Score = 39.3 bits (90), Expect = 0.009
 Identities = 58/268 (21%), Positives = 99/268 (36%), Gaps = 24/268 (8%)

Query: 146  EDWKKAREEKQKKLIELQAGKKSLEDQVEMLRTVKEEAEKPEREAKEQHQKLWEE-QLAA 204
            E  ++   +K  KL E + G    +++       +  A     EA+++ + + E  +   
Sbjct: 1747 EGSQRLNRDKDPKLGEAE-GDAMAQEREGKTHNSETSAGSELGEAEQEGEGISERGETGG 1805

Query: 205  AKAQQEQELAADAFKELDDD---MDGTVSVTELQTHPELDTDGDGALS-EAEAQAL-LSG 259
              +  E  L  +A    D D    DG   +   +   E   + +G  + EAE  A    G
Sbjct: 1806 QGSGHEDNLQGEAAAGGDQDPGQSDGAEGIEAPEAEGEAQPESEGVEAPEAEGDAQEAEG 1865

Query: 260  DTQTDATSFYDRVWAAIRDKYRSEALPT--DLPAPSAPDLTEPKEEQPPVPSSPTEEEEE 317
            + Q ++             +   EA P   D+  P A    +P+ E    P +  E + E
Sbjct: 1866 EAQPESEDVE-------APEAEGEAQPESEDVETPEAEWEVQPESEGAEAPEAEKEAQPE 1918

Query: 318  EEE--------EEEEEAEEEEEEEDSEEAPPPLSPPQPASPAEEDKMPPYDEQTQAFIDA 369
             E         E+E E+E  E +E  E A       QP S   E +    + Q ++    
Sbjct: 1919 TESVEALETEGEDEPESEGAEAQEAEEAAQEAEGQTQPESEVIESQEAEEEAQPESEDVE 1978

Query: 370  AQEARNKFEEAERSLKDMEESIRNLEQE 397
            A E   + +EAE   +   E +   E E
Sbjct: 1979 ALEVEVETQEAEGEAQPESEDVEAPEAE 2006



 Score = 36.2 bits (82), Expect = 0.076
 Identities = 43/205 (20%), Positives = 76/205 (37%), Gaps = 22/205 (10%)

Query: 153  EEKQKKLIELQAGKKSLEDQVEMLRTVKEEAEKPEREAKEQHQKLWEEQLAAAKAQQEQE 212
            E   ++ ++L+  K+  E +      V+ E  K E   +E+  +L E +    + QQE+E
Sbjct: 1294 ENTVQEEVQLEETKEGTEGEGLQEEAVQLEETKTEEGLQEEGVQLEETKETEGEGQQEEE 1353

Query: 213  LAADAFKELDDD--MDGTVSVTELQTHPELDTDGDGALSEAEAQALLSGDTQTDATSFYD 270
               +  +E   +   +  V + E++  PE    G+ AL E   +  L  +          
Sbjct: 1354 AQLEEIEETGGEGLQEEGVQLEEVKEGPEGGLQGE-ALEEGLKEEGLPEE---------- 1402

Query: 271  RVWAAIRDKYRSEALPTDLPAPSAPDLTEPKE------EQPPVPSSPTEEEEEEEEEEEE 324
                ++  +  SEA   D       D  + +E         P P+  TEE  E      E
Sbjct: 1403 ---GSVHGQELSEASSPDGKGSQEDDPVQEEEAGRASASAEPCPAEGTEEPTEPPSHLSE 1459

Query: 325  EAEEEEEEEDSEEAPPPLSPPQPAS 349
                  E +   +  P L  P  A+
Sbjct: 1460 TDPSASERQSGSQLEPGLEKPPGAT 1484



 Score = 35.4 bits (80), Expect = 0.13
 Identities = 44/205 (21%), Positives = 76/205 (37%), Gaps = 21/205 (10%)

Query: 153  EEKQKKLIELQAGKKSLEDQVEMLRTVKEEAEKPEREAKEQHQKLWEEQLAAAKAQQEQE 212
            E++ ++  E Q    +LE   E   TV+EE +  E +   + + L EE +   + + E+ 
Sbjct: 1273 EDEAERDSEEQRASSNLEQLAE--NTVQEEVQLEETKEGTEGEGLQEEAVQLEETKTEEG 1330

Query: 213  LAADAFK-ELDDDMDGTVSVTELQTHPELDTDGDGALSEAEAQALLSGDTQTDATSFYDR 271
            L  +  + E   + +G     E     E++  G   L E   Q               + 
Sbjct: 1331 LQEEGVQLEETKETEGEGQQEEEAQLEEIEETGGEGLQEEGVQL--------------EE 1376

Query: 272  VWAAIRDKYRSEALPTDLPAPSAPDLTEPKEEQPPVPSSP----TEEEEEEEEEEEEEAE 327
            V        + EAL   L     P+      ++    SSP    ++E++  +EEE   A 
Sbjct: 1377 VKEGPEGGLQGEALEEGLKEEGLPEEGSVHGQELSEASSPDGKGSQEDDPVQEEEAGRAS 1436

Query: 328  EEEEEEDSEEAPPPLSPPQPASPAE 352
               E   +E    P  PP   S  +
Sbjct: 1437 ASAEPCPAEGTEEPTEPPSHLSETD 1461


>gi|14249738 N-acetylglucosamine-1-phosphotransferase, gamma subunit
           [Homo sapiens]
          Length = 305

 Score = 56.6 bits (135), Expect = 5e-08
 Identities = 32/105 (30%), Positives = 46/105 (43%), Gaps = 5/105 (4%)

Query: 411 LYSQCYELTTNEYVYRLCPFKLVSQKPKL---GGSPTSLGTWGSWIGPDHDKFSAMKYEQ 467
           L  +C+ L  + Y Y  CPF  V+Q  +          LG W  W    ++ F+ M    
Sbjct: 67  LSGKCFSLVESTYKYEFCPFHNVTQHEQTFRWNAYSGILGIWHEW-EIANNTFTGMWMRD 125

Query: 468 GTGCWQGPNRSTTVRLLCGKETMVTSTTEPSRCEYLMELMTPAAC 512
           G  C +  +R + V L CGK   +   +EPS C Y +   TP  C
Sbjct: 126 GDAC-RSRSRQSKVELACGKSNRLAHVSEPSTCVYALTFETPLVC 169


>gi|154759293 cysteine-rich hydrophobic domain 1 [Homo sapiens]
          Length = 224

 Score = 56.6 bits (135), Expect = 5e-08
 Identities = 32/68 (47%), Positives = 39/68 (57%), Gaps = 11/68 (16%)

Query: 285 LPTDLPAPSAPDLTEPKEEQPPVPSSPT-----------EEEEEEEEEEEEEAEEEEEEE 333
           LP      +  +L E +EE+    SS             +EE+EEEEEEEEE EEEEEEE
Sbjct: 5   LPNMAEFDTISELEEEEEEEAATSSSSPSSSSSVSGPDDDEEDEEEEEEEEEEEEEEEEE 64

Query: 334 DSEEAPPP 341
           + EEAPPP
Sbjct: 65  EEEEAPPP 72



 Score = 29.3 bits (64), Expect = 9.3
 Identities = 17/57 (29%), Positives = 29/57 (50%), Gaps = 4/57 (7%)

Query: 325 EAEEEEEEEDSEEAPPPLSPPQPASPAEEDKMPPYDEQTQAFIDAAQEARNKFEEAE 381
           E EEEEEEE +  +  P S    + P ++++    DE+ +   +  +E   + EE E
Sbjct: 16  ELEEEEEEEAATSSSSPSSSSSVSGPDDDEE----DEEEEEEEEEEEEEEEEEEEEE 68


>gi|239745079 PREDICTED: Putative golgin subfamily A member 6-like
           protein 6 [Homo sapiens]
          Length = 724

 Score = 55.5 bits (132), Expect = 1e-07
 Identities = 54/294 (18%), Positives = 133/294 (45%), Gaps = 15/294 (5%)

Query: 117 KEKGRKERESLQQMAEVTREGFRLKKILIEDWKKAREEKQ---KKLIELQAGKKSLEDQV 173
           +EK R++ E +++  E  R   R ++++ E  +K R +++   +K  +++  ++ + ++ 
Sbjct: 381 EEKIREQEEKIREQEEKMR---RQEEMMWEKEEKMRRQEEMMWEKEEKMRRQEEMMWEKE 437

Query: 174 EMLRTVKEEAEKPEREAKEQHQKLWEEQLAAAKAQQEQELAADAFKELDDDMDGTVSVTE 233
           E +R ++E+  + E+  +++ ++  EE++   + +QEQE      +E   + +  +   E
Sbjct: 438 EKIRELEEKMHEQEKIREQEEKRQEEEKIREQEKRQEQEAKMWRQEEKIREQEEKIREQE 497

Query: 234 --LQTHPELDTDGDGALSEAEAQALLSGDTQTDATSFYDRVWA------AIRDKYRSEAL 285
             +    E   + +    E + Q       Q +     + +W          +K R +  
Sbjct: 498 EKMWRQEEKIHEQEKIREEEKRQEQEEMWRQEEKIREQEEIWRQKEKIHEQEEKIRKQEE 557

Query: 286 PTDLPAPSAPDLTEP-KEEQPPVPSSPTEEEEEEEEEEEEEAEEEEEEEDSEEAPPPLSP 344
                     D  E  +E++  V     +  E+EE+  E+E +  E+EE ++E    +  
Sbjct: 558 KMWRQEEKMHDQEEKIREQEEKVWRQEEKIREQEEKIREQEEKIREQEEMTQEQEEKMGE 617

Query: 345 PQPASPAEEDKMPPYDEQTQAFIDAAQEARNKFEEAERSLKDMEESIRNLEQEI 398
            +     +E+KM   +E+ +   +  +E   K  E E  +++ EE ++  E+++
Sbjct: 618 QEEKMCEQEEKMQEQEEKMRRQEEKIREQEKKIREQEEKIREQEEMMQEQEEKM 671



 Score = 55.1 bits (131), Expect = 2e-07
 Identities = 50/279 (17%), Positives = 113/279 (40%), Gaps = 23/279 (8%)

Query: 122 KERESLQQMAEVTREGFRLKKILIEDWKKAREEKQKKLIELQAGKKSLEDQVEMLRTVKE 181
           +E E   ++ +   E    ++  I++W++  +E+++K+ E +   + + +Q E +R  +E
Sbjct: 347 EENELWNRLNQQQEEKMWRQEEKIQEWEEKIQEQEEKIREQE---EKIREQEEKMRRQEE 403

Query: 182 EAEKPEREAKEQHQKLWEEQLAAAKAQQEQELAADAFKELDDDMDGTVSVTELQTHPELD 241
              + E + + Q + +WE++    + ++      +  +EL++ M     + E +   + +
Sbjct: 404 MMWEKEEKMRRQEEMMWEKEEKMRRQEEMMWEKEEKIRELEEKMHEQEKIREQEEKRQEE 463

Query: 242 TDGDGALSEAEAQALLSGDTQTDATSFYDRVWAAIRDKYRSEALPTDLPAPSAPDLTEPK 301
                     E +A               ++W    +K R +               E  
Sbjct: 464 EKIREQEKRQEQEA---------------KMWRQ-EEKIREQEEKIREQEEKMWRQEEKI 507

Query: 302 EEQPPVPSSPTEEEEEEEEEEEEEAEEEEE----EEDSEEAPPPLSPPQPASPAEEDKMP 357
            EQ  +      +E+EE   +EE+  E+EE    +E   E    +   +     +E+KM 
Sbjct: 508 HEQEKIREEEKRQEQEEMWRQEEKIREQEEIWRQKEKIHEQEEKIRKQEEKMWRQEEKMH 567

Query: 358 PYDEQTQAFIDAAQEARNKFEEAERSLKDMEESIRNLEQ 396
             +E+ +   +       K  E E  +++ EE IR  E+
Sbjct: 568 DQEEKIREQEEKVWRQEEKIREQEEKIREQEEKIREQEE 606



 Score = 51.6 bits (122), Expect = 2e-06
 Identities = 58/305 (19%), Positives = 132/305 (43%), Gaps = 30/305 (9%)

Query: 117 KEKGRKERESLQQMAEVTREGFRLKKILIEDWK-KAREEKQKKLIELQAGKKSLEDQVEM 175
           +EK R++ E + +  E  RE   L++ + E  K + +EEK+++  +++  +K  E + +M
Sbjct: 423 EEKMRRQEEMMWEKEEKIRE---LEEKMHEQEKIREQEEKRQEEEKIREQEKRQEQEAKM 479

Query: 176 LRTVKEEAEKPEREAKEQHQKLWEEQLAAAKAQQEQELAADAFKELDDDM----DGTVSV 231
            R  +E+  + E + +EQ +K+W ++    K  +++++  +  ++  ++M    +     
Sbjct: 480 WRQ-EEKIREQEEKIREQEEKMWRQE---EKIHEQEKIREEEKRQEQEEMWRQEEKIREQ 535

Query: 232 TELQTHPELDTDGDGALSEAEA----QALLSGDTQTDATSFYDRVWAA----------IR 277
            E+    E   + +  + + E     Q     D +       ++VW            IR
Sbjct: 536 EEIWRQKEKIHEQEEKIRKQEEKMWRQEEKMHDQEEKIREQEEKVWRQEEKIREQEEKIR 595

Query: 278 DKYRSEALPTDLPAPSAPDLTEPKEEQPPVPSSPTEEEE----EEEEEEEEEAEEEEEEE 333
           ++        ++       + E +E+         E+EE    +EE+  E+E +  E+EE
Sbjct: 596 EQEEKIREQEEMTQEQEEKMGEQEEKMCEQEEKMQEQEEKMRRQEEKIREQEKKIREQEE 655

Query: 334 DSEEAPPPLSPPQPASPAEEDKMPPYDEQTQAFIDAAQEARNKFEEAERSLKDMEESIRN 393
              E    +   +     +E+KM   +E+ Q   +  +    K  E E  L+  EE ++ 
Sbjct: 656 KIREQEEMMQEQEEKMWEQEEKMCEQEEKMQEQEEKMRRQEEKMWEQEVRLRQQEEKMQE 715

Query: 394 LEQEI 398
            ++ +
Sbjct: 716 HQEHL 720



 Score = 45.1 bits (105), Expect = 2e-04
 Identities = 50/260 (19%), Positives = 115/260 (44%), Gaps = 27/260 (10%)

Query: 117 KEKGRKERESLQQMAEVTREGFRLKKILIEDWKKAREEKQKKLIELQAGKKSLEDQVEML 176
           +EK R++ E +++  E   + +R ++ + E  K   EEK+++  E+   ++ + +Q E+ 
Sbjct: 483 EEKIREQEEKIREQEE---KMWRQEEKIHEQEKIREEEKRQEQEEMWRQEEKIREQEEIW 539

Query: 177 RTVKEEAEKPEREAKEQHQKLW--EEQLAAAKA---QQEQELAADAFKELDDDMDGTVSV 231
           R  KE+  + E + ++Q +K+W  EE++   +    +QE+++     K  + +       
Sbjct: 540 RQ-KEKIHEQEEKIRKQEEKMWRQEEKMHDQEEKIREQEEKVWRQEEKIREQEEKIREQE 598

Query: 232 TELQTHPELDTDGDGALSEAEAQALLSGDTQTDATSFYDRVWAAIRDKYRSEALPTDLPA 291
            +++   E+  + +  + E E +     +   +      R    IR++ +          
Sbjct: 599 EKIREQEEMTQEQEEKMGEQEEKMCEQEEKMQEQEEKMRRQEEKIREQEKK--------- 649

Query: 292 PSAPDLTEPKEEQPPVPSSPTEEEEEEEEEEEEEAEE----EEEEEDSEEAPPPLSPPQP 347
                + E +E+         E+EE+  E+EE+  E+    +E+EE        +   + 
Sbjct: 650 -----IREQEEKIREQEEMMQEQEEKMWEQEEKMCEQEEKMQEQEEKMRRQEEKMWEQEV 704

Query: 348 ASPAEEDKMPPYDEQTQAFI 367
               +E+KM  + E  +A I
Sbjct: 705 RLRQQEEKMQEHQEHLEAAI 724



 Score = 35.0 bits (79), Expect = 0.17
 Identities = 25/102 (24%), Positives = 47/102 (46%), Gaps = 9/102 (8%)

Query: 297 LTEPKEEQPPVPSSPTEEEEEEEEEEEEEAEEEEEEEDSEEAPPPLSPPQPASPAEEDKM 356
           L + +EE+        +E EE+ +E+EE+  E+EE+   +E              +E+ M
Sbjct: 355 LNQQQEEKMWRQEEKIQEWEEKIQEQEEKIREQEEKIREQEEK---------MRRQEEMM 405

Query: 357 PPYDEQTQAFIDAAQEARNKFEEAERSLKDMEESIRNLEQEI 398
              +E+ +   +   E   K    E  + + EE IR LE+++
Sbjct: 406 WEKEEKMRRQEEMMWEKEEKMRRQEEMMWEKEEKIRELEEKM 447


>gi|148746195 trichohyalin [Homo sapiens]
          Length = 1943

 Score = 55.5 bits (132), Expect = 1e-07
 Identities = 66/306 (21%), Positives = 126/306 (41%), Gaps = 19/306 (6%)

Query: 113 ENTCKEKGRKERESLQQMAEVTR-EGFRLKKILIEDWKKAREEKQKKLIELQAGKKSLED 171
           E   K +  + R+ L++  E  R E  R K+ L  D ++ R E+  KL E +  ++  E 
Sbjct: 444 EQRLKREQEERRDWLKREEETERHEQERRKQQLKRDQEEERRERWLKLEE-EERREQQER 502

Query: 172 QVEMLRTVKEEAEKPEREAKEQHQKLWEEQLAAAKAQQEQELAADAFKELDDDMDGTVSV 231
           + + LR  +EE  +   + +E+ ++L +   +  + ++EQE   +   + +++       
Sbjct: 503 REQQLRREQEERREQRLKRQEEEERLQQRLRSEQQLRREQEERREQLLKREEEKRLEQER 562

Query: 232 TELQTHPELDTDGDGAL--SEAEAQALLSGDTQTDATSFYDR--VWAAIRDKYRSEALPT 287
            E +   E +   D  L   E   Q  L  + +        R  V    +++ R + L  
Sbjct: 563 REQRLKREQEERRDQLLKREEERRQQRLKREQEERLEQRLKREEVERLEQEERREQRLKR 622

Query: 288 DLPAPSAPDLTEPKEEQPPVPSSPTEEEEEEEEEEEEEAEEEEE----------EEDSEE 337
           + P           EEQ          E++E  E+  + EEEEE          EE+  E
Sbjct: 623 EEPEEERRQQLLKSEEQEERRQQQLRREQQERREQRLKREEEEERLEQRLKREHEEERRE 682

Query: 338 APPPLSPPQPASPAEEDKMPPYDEQTQAFIDAAQE---ARNKFEEAERSLKDMEESIRNL 394
                   + A    + ++P +  Q ++  DA Q    +R + +E +R  ++ EE  R  
Sbjct: 683 QELAEEEQEQARERIKSRIPKWQWQLESEADARQSKVYSRPRKQEGQRRRQEQEEKRRRR 742

Query: 395 EQEISF 400
           E E+ +
Sbjct: 743 ESELQW 748



 Score = 48.1 bits (113), Expect = 2e-05
 Identities = 60/289 (20%), Positives = 119/289 (41%), Gaps = 18/289 (6%)

Query: 117 KEKGRKERESLQQMAEVTREGFRLKKILIEDWKKAREEKQKKLIELQAGKKSLEDQVEML 176
           KE+ + + E  Q+  E+  E  +L+K+  ++ ++ R+E++++   L+  ++ L  + E  
Sbjct: 255 KEEEKLQEEEPQRQRELQEEEEQLRKLERQELRRERQEEEQQQQRLRR-EQQLRRKQEEE 313

Query: 177 RTVKEEAEKPEREAKEQHQKLWEEQLAAAKAQQEQELAADAFKELDDDMDGTVSVTELQT 236
           R  ++E  + ++E +EQ ++  E+QL   + +QE+       +E +++        E Q 
Sbjct: 314 RREQQEERREQQERREQQEERREQQL---RREQEERREQQLRREQEEER------REQQL 364

Query: 237 HPELDTDGDGALSEAEAQALLSGDTQTDATSFYDRVWAAIRDKYRSEALPTDLPAPSAPD 296
             E + +        E Q       + +     ++     +   R + L  +        
Sbjct: 365 RREQEEERREQQLRREQQLRREQQLRREQQLRREQQLRREQQLRREQQLRREQQLRREQQ 424

Query: 297 LTEPKEEQPPVPSSPTEEEEEEEEEEEEE------AEEEEEEEDSEEAPPPLSPPQPASP 350
           L   +EE+        E  E+  + E+EE       EEE E  + E     L   Q    
Sbjct: 425 LRREQEEERHEQKHEQERREQRLKREQEERRDWLKREEETERHEQERRKQQLKRDQEEER 484

Query: 351 AEE-DKMPPYDEQTQAFIDAAQEARNKFEEAERSLKDMEESIRNLEQEI 398
            E   K+   + + Q      Q  R + E  E+ LK  EE  R L+Q +
Sbjct: 485 RERWLKLEEEERREQQERREQQLRREQEERREQRLKRQEEEER-LQQRL 532



 Score = 47.8 bits (112), Expect = 3e-05
 Identities = 57/298 (19%), Positives = 121/298 (40%), Gaps = 28/298 (9%)

Query: 117 KEKGRKERESLQQMAEVTREGFRLKKILIEDWKKAREEKQKKLIELQAGKKSLEDQVEML 176
           K++ R+ER+      E  +E  + + +L ++ +K +EE+ ++  ELQ      E++ ++ 
Sbjct: 226 KQQQRRERQDRVFQEEEEKEWRKRETVLRKEEEKLQEEEPQRQRELQ------EEEEQLR 279

Query: 177 RTVKEEAEKPEREAKEQHQKLWEEQLAAAKAQQEQELAADAFKELDDDMDGTVSVTELQT 236
           +  ++E  +  +E ++Q Q+L  EQ    K ++E+    +  +E  +  +      E Q 
Sbjct: 280 KLERQELRRERQEEEQQQQRLRREQQLRRKQEEERREQQEERREQQERREQQEERREQQL 339

Query: 237 HPELDTDGDGAL----SEAEAQALLSGDTQTDATSFYDRVWAAIRDKY---------RSE 283
             E +   +  L     E   +  L  + + +      R    +R +          R +
Sbjct: 340 RREQEERREQQLRREQEEERREQQLRREQEEERREQQLRREQQLRREQQLRREQQLRREQ 399

Query: 284 ALPTDLPAPSAPDLTEPKEEQPPVPSSPTEEEEEEEEEEEEEAEEEEEEEDSEEAPPPLS 343
            L  +        L   ++ +        +EEE  E++ E+E  E+  + + EE    L 
Sbjct: 400 QLRREQQLRREQQLRREQQLRREQQLRREQEEERHEQKHEQERREQRLKREQEERRDWLK 459

Query: 344 PPQPASPAEEDKMPPYDEQTQAFIDAAQEARNKF----EEAERSLKDMEESIRNLEQE 397
             +     E+++      + Q   D  +E R ++    EE  R  ++  E     EQE
Sbjct: 460 REEETERHEQER-----RKQQLKRDQEEERRERWLKLEEEERREQQERREQQLRREQE 512



 Score = 45.4 bits (106), Expect = 1e-04
 Identities = 70/304 (23%), Positives = 124/304 (40%), Gaps = 33/304 (10%)

Query: 117  KEKGRKERESLQQMAEVTREGFRLKKILIEDWKKAREEKQ-----KKLIELQAGKKSLED 171
            +E+ RKE++ LQ+  E  +   R K+   E  ++ REE+Q     ++L+  +  K+  ++
Sbjct: 896  QEQLRKEQQLLQEEEEELQREEREKRRRQEQERQYREEEQLQQEEEQLLREEREKRRRQE 955

Query: 172  QVEMLRT-----VKEE---AEKPEREAKEQHQKLWEEQLAAAKAQQEQELAADAFKELDD 223
            +    R       KEE    E+PE+  +++ +K + E+    + ++EQ L  +  K    
Sbjct: 956  RERQYRKDKKLQQKEEQLLGEEPEKRRRQEREKKYREE-EELQQEEEQLLREEREKRRRQ 1014

Query: 224  DMDGTV-SVTELQTHPEL---DTDGDGALSEAEAQALLSGDTQTDATSFYD-----RVWA 274
            + +       ELQ   E    +      L E E Q     + Q +           R   
Sbjct: 1015 EWERQYRKKDELQQEEEQLLREEREKRRLQERERQYREEEELQQEEEQLLGEERETRRRQ 1074

Query: 275  AIRDKYRSEALPTDLPAPSAPDLTE-PKEEQPPVPSSPTEEEEEEEEEEEEEAEEEEEEE 333
             +  +YR E    +L       L E P++ +         EEEE ++EEE+   EE E+ 
Sbjct: 1075 ELERQYRKEE---ELQQEEEQLLREEPEKRRRQERERQCREEEELQQEEEQLLREEREKR 1131

Query: 334  DSEEAPPPLSPPQPASPAEEDKMPPYDEQTQAFIDAAQEARNKFEEAERSLKDMEESIRN 393
              +E        +     EE  +    E+ +      QE   ++ E E  L+  EE +  
Sbjct: 1132 RRQELERQYREEEEVQQEEEQLLREEPEKRR-----RQELERQYRE-EEELQQEEEQLLR 1185

Query: 394  LEQE 397
             EQE
Sbjct: 1186 EEQE 1189



 Score = 45.1 bits (105), Expect = 2e-04
 Identities = 65/280 (23%), Positives = 117/280 (41%), Gaps = 37/280 (13%)

Query: 117  KEKGRKERESLQQMAEVTREGFRLKKILIEDWKKAREEKQKKLIELQAGKKSLEDQVEML 176
            +E+ R+ERE  QQ++   R+    +K  +E+ K  R+E+++K          +ED+ ++ 
Sbjct: 1560 EEQLRQEREE-QQLSRQERD----RKFRLEEQKVRRQEQERKF---------MEDEQQLR 1605

Query: 177  RTVKEEAEKPEREAKEQHQKLWEEQLAAAKAQQEQELAADAFKELDDDMDGTVSVTELQT 236
            R   ++  + ER+ K +     +EQL   + +Q+        K L+++      +   + 
Sbjct: 1606 RQEGQQQLRQERDRKFRE----DEQLLQEREEQQLHRQERDRKFLEEE----PQLRRQER 1657

Query: 237  HPELDTDGDGALSEAEAQALLSGDTQTDATSFYDRVWAAIRDKYRSEALPTDLPAPSAPD 296
              +L  D D    E E Q L  G+ Q       DR       K+R E             
Sbjct: 1658 EQQLRHDRDRKFRE-EEQLLQEGEEQQLRRQERDR-------KFREEEQQLRRQERERKF 1709

Query: 297  LTEPKE-EQPPVPSSPTEEEEEEEEEEEEEAEEEEEEED--SEEAPPPLSPPQPASPAEE 353
            L E ++  +  +     EEE+  +E E+E+   +E       EE   P    Q     E 
Sbjct: 1710 LQEEQQLRRQELERKFREEEQLRQETEQEQLRRQERYRKILEEEQLRPEREEQQLRRQER 1769

Query: 354  DKMPPYDEQTQAFID----AAQEARNKFEEAERSLKDMEE 389
            D+    +EQ +   +     +QE+  KF E E+  ++ EE
Sbjct: 1770 DRKFREEEQLRQEREEQQLRSQESDRKFREEEQLRQEREE 1809



 Score = 44.3 bits (103), Expect = 3e-04
 Identities = 63/289 (21%), Positives = 113/289 (39%), Gaps = 43/289 (14%)

Query: 122  KERESLQQMAEVTREGFRLKKILIEDWKKAREEKQKKLIELQAGKKSLEDQVEMLRTVKE 181
            +ER   QQ  E  R  F         W+   EEK ++  +  + +  L +Q E     +E
Sbjct: 751  EERAHRQQQEEEQRRDFT--------WQWQAEEKSERGRQRLSARPPLREQRERQLRAEE 802

Query: 182  EAEKPEREAKEQHQKLWEEQLAAAKAQQEQELAADAFKELDDDMDGTVSVTELQTHPE-L 240
              ++ +R   E+ +K   EQ    + ++E+EL    F E ++ +       +LQ   + L
Sbjct: 803  RQQREQRFLPEEEEK---EQRRRQRREREKELQ---FLEEEEQLQRRERAQQLQEEEDGL 856

Query: 241  DTDGDGALSEAEAQALLSGDTQTDATSFYDRVWAAIRDKYRSEALPTDLPAPSAPD---- 296
              D +   S+ + +               D+ W    ++ R     T    P+  +    
Sbjct: 857  QEDQERRRSQEQRR---------------DQKWRWQLEEERKRRRHTLYAKPALQEQLRK 901

Query: 297  ----LTEPKEE-QPPVPSSPTEEEEEEEEEEEEEAEEEEEEEDSEEAPPPLSPPQPASPA 351
                L E +EE Q         +E+E +  EEE+ ++EEE+   EE        +     
Sbjct: 902  EQQLLQEEEEELQREEREKRRRQEQERQYREEEQLQQEEEQLLREEREKRRRQERERQYR 961

Query: 352  EEDKMPPYDEQ---TQAFIDAAQEARNKFEEAERSLKDMEESIRNLEQE 397
            ++ K+   +EQ    +      QE   K+ E E  L+  EE +   E+E
Sbjct: 962  KDKKLQQKEEQLLGEEPEKRRRQEREKKYRE-EEELQQEEEQLLREERE 1009



 Score = 42.0 bits (97), Expect = 0.001
 Identities = 59/281 (20%), Positives = 119/281 (42%), Gaps = 27/281 (9%)

Query: 117  KEKGRKERESLQQMAEVTREGFRLKKILIEDWKKAREEKQKKLIELQAGKKSLEDQVEML 176
            + + +K R  L++  +  R     K  L E  +K ++  Q++  ELQ  ++    + E  
Sbjct: 868  QRRDQKWRWQLEEERKRRRHTLYAKPALQEQLRKEQQLLQEEEEELQREEREKRRRQEQE 927

Query: 177  RTVKEEAEKPEREAKEQHQKLWEEQLAAAKAQQEQELAAD-AFKELDDDMDGTVSVTELQ 235
            R  +EE    E+  +E+ Q L EE+    + ++E++   D   ++ ++ + G       +
Sbjct: 928  RQYREE----EQLQQEEEQLLREEREKRRRQERERQYRKDKKLQQKEEQLLGEEPEKRRR 983

Query: 236  THPELDTDGDGALSEAEAQALLSGDTQTDATSFYDRVWAAIRDKYRSEALPTDLPAPSAP 295
               E     +  L + E Q LL  + +      ++R       +YR +    +L      
Sbjct: 984  QEREKKYREEEELQQEEEQ-LLREEREKRRRQEWER-------QYRKK---DELQQEEEQ 1032

Query: 296  DLTEPKEEQPPVPSSPTEEEEEEEEEEEEEAEEEEEEEDSEEAPPPLSPPQPASPAEEDK 355
             L E +E++         +E E +  EEEE ++EEE+   EE              +E++
Sbjct: 1033 LLREEREKR-------RLQERERQYREEEELQQEEEQLLGEERETRRRQELERQYRKEEE 1085

Query: 356  MPPYDEQTQAFIDAAQEARNKFEEAERSLKDMEESIRNLEQ 396
            +   +EQ    +   +  + + +E ER  ++ EE  +  EQ
Sbjct: 1086 LQQEEEQ----LLREEPEKRRRQERERQCREEEELQQEEEQ 1122



 Score = 41.2 bits (95), Expect = 0.002
 Identities = 60/294 (20%), Positives = 114/294 (38%), Gaps = 34/294 (11%)

Query: 119 KGRKERESLQQMAEVTREGFRLKKILIEDWKKAREEKQKKLI-----ELQAGKKSLEDQV 173
           K  +E E L+Q  +   E  R ++ L E+ ++   E+ K  I     +L++   + + +V
Sbjct: 660 KREEEEERLEQRLKREHEEERREQELAEEEQEQARERIKSRIPKWQWQLESEADARQSKV 719

Query: 174 EMLRTVKEEAEKPEREAKEQHQKL-----WEEQLAAAKAQQEQELAADAFKELDDDMDGT 228
              R  K+E ++  +E +E+ ++      W+E+  A + QQE+E   D   +   +    
Sbjct: 720 YS-RPRKQEGQRRRQEQEEKRRRRESELQWQEEERAHRQQQEEEQRRDFTWQWQAEEKSE 778

Query: 229 VSVTELQTHPELDTDGDGALSEAEAQALLSGDTQTDATSFYDRVWAAIRDKYRSEALPTD 288
                L   P L    +  L   E Q       Q +     +      R + R E     
Sbjct: 779 RGRQRLSARPPLREQRERQLRAEERQ-------QREQRFLPEEEEKEQRRRQRRER---- 827

Query: 289 LPAPSAPDLTEPKEEQPPVPSSPTEEEEEEEEEEEEEAEEEEEEEDS------EEAPPPL 342
                   L E ++ Q    +   +EEE+  +E++E    +E+  D       EE     
Sbjct: 828 --EKELQFLEEEEQLQRRERAQQLQEEEDGLQEDQERRRSQEQRRDQKWRWQLEEERKRR 885

Query: 343 SPPQPASPAEEDKMPPYDEQTQAFIDAAQEARNKFEEAERSLKDMEESIRNLEQ 396
                A PA ++++     + Q  +   +E   + E  +R  ++ E   R  EQ
Sbjct: 886 RHTLYAKPALQEQL----RKEQQLLQEEEEELQREEREKRRRQEQERQYREEEQ 935



 Score = 40.0 bits (92), Expect = 0.005
 Identities = 61/284 (21%), Positives = 116/284 (40%), Gaps = 65/284 (22%)

Query: 119  KGRKERESLQQMAEVT-REGFRLKKILIEDWKKAREEKQKKLI--ELQAGKKSLEDQVEM 175
            K R+E + LQ+  E   R   R +K   E+ +  R+E+++K +  E Q  ++ LE +   
Sbjct: 1668 KFREEEQLLQEGEEQQLRRQERDRKFREEEQQLRRQERERKFLQEEQQLRRQELERKFRE 1727

Query: 176  LRTVKEEAEKPEREAKEQHQKLWEEQLAAAKAQQEQELAADAFKELDDDMDGTVSVTELQ 235
               +++E E+ +   +E+++K+ EE+    + +++Q    +  ++  ++           
Sbjct: 1728 EEQLRQETEQEQLRRQERYRKILEEEQLRPEREEQQLRRQERDRKFREE----------- 1776

Query: 236  THPELDTDGDGALSEAEAQALLSGDTQTDATSFYDRVWAAIRDKYRSEALPTDLPAPSAP 295
                     +    E E Q L S ++        DR       K+R E            
Sbjct: 1777 ---------EQLRQEREEQQLRSQES--------DR-------KFREEE----------- 1801

Query: 296  DLTEPKEEQPPVPSSPTEEE--EEEEEEEEEEAEEEEEEEDSEEAPPPLSPPQPASPAEE 353
             L + +EEQ   P     +   EEE+ + EE+ +   +E D +         Q  S  EE
Sbjct: 1802 QLRQEREEQQLRPQQRDGKYRWEEEQLQLEEQEQRLRQERDRQYRAEEQFATQEKSRREE 1861

Query: 354  DKMPPYDEQTQAFIDAAQEARNKFEEAERSLKDMEESIRNLEQE 397
             ++   +EQ             + +E ER L+  EE IR  ++E
Sbjct: 1862 QELWQEEEQ------------KRRQERERKLR--EEHIRRQQKE 1891



 Score = 39.7 bits (91), Expect = 0.007
 Identities = 59/287 (20%), Positives = 119/287 (41%), Gaps = 24/287 (8%)

Query: 116  CKEKGRKERESLQQMAEVTREGFR-LKKILIEDWKKAREEKQKKLIELQAGKKSLEDQVE 174
            CK +  ++   L+      R+  + L+ +L E  ++ RE+++++    Q   +   ++ +
Sbjct: 1242 CKGRENEQFRQLEDSQLRDRQSQQDLQHLLGEQQERDREQERRRW---QQRDRHFPEEEQ 1298

Query: 175  MLRTVKEEAEKPEREAKEQHQKLWEEQLAAAKAQQEQELAADAFKELDDDMDGTVSVTEL 234
            + R  ++EA++ +R+++E+ Q L EE+    + Q+      +  + L +  +  +   E 
Sbjct: 1299 LEREEQKEAKRRDRKSQEEKQLLREEREEKRRRQETDRKFREEEQLLQEREEQPLRRQER 1358

Query: 235  QT---HPELDTDGDGALSEAEAQALLSGDTQTDATSFYDRVWAAIRDKYRSEALPTDLPA 291
                   EL     G     E Q L   + +      + +    +R + R + L  D   
Sbjct: 1359 DRKFREEELRHQEQGRKFLEEEQRLRRQERERK----FLKEEQQLRCQEREQQLRQDR-- 1412

Query: 292  PSAPDLTEPKEEQPPVPSSPTEEEEEEEEEEEEEAEEEEEEEDSEEAPPPLSPPQPASPA 351
                D    +EEQ        +E + +  EEE++   +E E    E    L   +     
Sbjct: 1413 ----DRKFREEEQ----QLSRQERDRKFREEEQQVRRQERERKFLEEEQQLRQERHRKFR 1464

Query: 352  EEDKMPPYDEQTQAFIDAAQEARNKFEEAERSLKDMEESIRNLEQEI 398
            EE+++    E+ Q      QE   KF E E+ L+  E   +  EQE+
Sbjct: 1465 EEEQLLQEREEQQLH---RQERDRKFLEEEQQLRRQERDRKFREQEL 1508



 Score = 39.3 bits (90), Expect = 0.009
 Identities = 56/257 (21%), Positives = 105/257 (40%), Gaps = 23/257 (8%)

Query: 145 IEDWKKAREEKQKKLIELQAGKKSLEDQVEMLRTVKEEAEKPEREAKEQHQKLWEEQLAA 204
           +++ K+AR + ++ L++    ++  EDQ       ++  E+P +  +++ Q+  E +LA 
Sbjct: 95  LDEEKRARCDGKESLLQ---DRRQEEDQRRFEPRDRQLEEEPGQRRRQKRQEQ-ERELAE 150

Query: 205 AKAQQEQELAADAFKELDDDMDGTVSVTELQTHPELDTDGDGALSEAEAQALLSGDTQT- 263
            + Q E++   +       D +      E Q   E   +      E + Q+    +T+  
Sbjct: 151 GEEQSEKQERLEQRDRQRRDEELWRQRQEWQEREERRAE------EEQLQSCKGHETEEF 204

Query: 264 -DATSFYDRVWAAIRDKYRSEALPTDLPAPSAPDLTEPKEEQPPVPSSPTEEEEEEEEEE 322
            D      R    +R K R E            D    +EE+       T   +EEE+ +
Sbjct: 205 PDEEQLRRRELLELRRKGREEK---QQQRRERQDRVFQEEEEKEWRKRETVLRKEEEKLQ 261

Query: 323 EEEAEEEEEEEDSEEAPPPLSPPQPASPAEEDKMPPYDEQTQAFIDAAQEARNKFEEAER 382
           EEE + + E ++ EE    L   +     +E      +EQ Q  +   Q+ R K EE  R
Sbjct: 262 EEEPQRQRELQEEEEQLRKLERQELRRERQE------EEQQQQRLRREQQLRRKQEEERR 315

Query: 383 SLKD--MEESIRNLEQE 397
             ++   E+  R  +QE
Sbjct: 316 EQQEERREQQERREQQE 332



 Score = 38.9 bits (89), Expect = 0.012
 Identities = 55/286 (19%), Positives = 110/286 (38%), Gaps = 16/286 (5%)

Query: 117  KEKGRKERESLQQMAEVTREGFRLKKILIEDWKKAREEKQKKLIELQAGKKSLEDQVEML 176
            +++ R   E  Q   E  +E  R  +   E+ +  REE+++K    +  +K  E++  + 
Sbjct: 1287 QQRDRHFPEEEQLEREEQKEAKRRDRKSQEEKQLLREEREEKRRRQETDRKFREEEQLLQ 1346

Query: 177  RTVKEEAEKPEREAKEQHQKLWEEQLAAAKAQQEQELAAD--AFKELDDDMDGTVSVTEL 234
               ++   + ER+ K + ++L  ++      ++EQ L       K L ++        E 
Sbjct: 1347 EREEQPLRRQERDRKFREEELRHQEQGRKFLEEEQRLRRQERERKFLKEEQQLRCQEREQ 1406

Query: 235  QTHPELD---TDGDGALSEAEAQALLSGDTQTDATSFYDRVWAAIRDKYRSEALPTDLPA 291
            Q   + D    + +  LS  E       + Q       +R +     + R E        
Sbjct: 1407 QLRQDRDRKFREEEQQLSRQERDRKFREEEQQVRRQERERKFLEEEQQLRQE---RHRKF 1463

Query: 292  PSAPDLTEPKEEQPPVPSSPTEEEEEEEEEEEEEAEEEEEEEDSEEAPPPLSPPQPASPA 351
                 L + +EEQ          +E + +  EEE +   +E D +     L   +P    
Sbjct: 1464 REEEQLLQEREEQ------QLHRQERDRKFLEEEQQLRRQERDRKFREQELRSQEPERKF 1517

Query: 352  EEDKMPPYDEQTQ-AFIDAAQEARNKFEEAERSLKDMEESIRNLEQ 396
             E++   + +Q Q  F+   Q+ R + E  ++  +D +   R  EQ
Sbjct: 1518 LEEEQQLHRQQRQRKFLQEEQQLRRQ-ERGQQRRQDRDRKFREEEQ 1562



 Score = 37.7 bits (86), Expect = 0.026
 Identities = 68/290 (23%), Positives = 119/290 (41%), Gaps = 36/290 (12%)

Query: 117  KEKGRKERESLQQMAEVTREGFRLKKILIEDWKKAR----EEKQKKLIELQAGKKSLEDQ 172
            +EK  +E E LQQ  E         ++L E+ +K R    E + +K  ELQ  ++ L  +
Sbjct: 986  REKKYREEEELQQEEE---------QLLREEREKRRRQEWERQYRKKDELQQEEEQLLRE 1036

Query: 173  VEMLRTVKEEAEKPEREAKEQHQKLWEEQLAAAKAQ--QEQELAADAFKELDDDMDGTVS 230
                R ++E  E+  RE +E  Q+  EEQL   + +  + QEL     KE +   +    
Sbjct: 1037 EREKRRLQER-ERQYREEEELQQE--EEQLLGEERETRRRQELERQYRKEEELQQEEEQL 1093

Query: 231  VTELQTHPELDTDGDGALSEAEAQALLSGDTQTDATSFYDRVWAAIRDKYRSEALPTDLP 290
            + E    PE     +      E + L   + Q        R    +  +YR E       
Sbjct: 1094 LRE---EPEKRRRQERERQCREEEELQQEEEQLLREEREKRRRQELERQYREEEEVQQEE 1150

Query: 291  APSAPDLTEPKEEQPPVPSSPTEEEEEEEEEEEEEAEEEEEEEDSEEAPPPLSPPQPASP 350
                 +  EP++ +         EEEE ++EEE+   EE+E+   E         +    
Sbjct: 1151 EQLLRE--EPEKRRRQELERQYREEEELQQEEEQLLREEQEKRRQE---------RERQY 1199

Query: 351  AEEDKMPPYDEQTQAFIDAAQEARNKFE---EAERSLKDMEESIRNLEQE 397
             EE+++    ++ Q + D  Q +  K++   E E +++D +   +  E E
Sbjct: 1200 REEEEL-QRQKRKQRYRDEDQRSDLKWQWEPEKENAVRDNKVYCKGRENE 1248



 Score = 32.0 bits (71), Expect = 1.4
 Identities = 63/311 (20%), Positives = 119/311 (38%), Gaps = 32/311 (10%)

Query: 113 ENTCKEKGRKERESLQQMAEVTREG-FRLKKILIEDWKKAREEKQKKLIELQAGKKSLED 171
           E   +E+  +  + L++  ++ RE   R ++ L  + +  RE++ ++  +L+  ++   +
Sbjct: 369 EEERREQQLRREQQLRREQQLRREQQLRREQQLRREQQLRREQQLRREQQLRREQQLRRE 428

Query: 172 QVEMLRTVKEEAEKPEREAK--EQHQKLW------------EEQLAAAKAQQEQELAADA 217
           Q E     K E E+ E+  K  ++ ++ W            E +    K  QE+E     
Sbjct: 429 QEEERHEQKHEQERREQRLKREQEERRDWLKREEETERHEQERRKQQLKRDQEEERRERW 488

Query: 218 FKELDDDMDGTVSVTELQTHPELDTDGDGALSEAEAQALLSGDTQTDATSFYDRVWAAIR 277
            K  +++        E Q   E +   +  L   E +  L    +++     +      +
Sbjct: 489 LKLEEEERREQQERREQQLRREQEERREQRLKRQEEEERLQQRLRSEQQLRRE------Q 542

Query: 278 DKYRSEALPTDLPAPSAPDLTEP--KEEQPPVPSSPTEEEEE--------EEEEEEEEAE 327
           ++ R + L  +       +  E   K EQ        + EEE        E+EE  E+  
Sbjct: 543 EERREQLLKREEEKRLEQERREQRLKREQEERRDQLLKREEERRQQRLKREQEERLEQRL 602

Query: 328 EEEEEEDSEEAPPPLSPPQPASPAEEDKMPPYDEQTQAFIDAAQEARNKFEEAERSLKDM 387
           + EE E  E+        +   P EE +      + Q      Q  R + E  E+ LK  
Sbjct: 603 KREEVERLEQEERREQRLKREEPEEERRQQLLKSEEQEERRQQQLRREQQERREQRLKRE 662

Query: 388 EESIRNLEQEI 398
           EE  R LEQ +
Sbjct: 663 EEEER-LEQRL 672



 Score = 29.3 bits (64), Expect = 9.3
 Identities = 29/146 (19%), Positives = 63/146 (43%), Gaps = 17/146 (11%)

Query: 119  KGRKERESLQQMAEVTREGFRLKKILIEDWKKAREEKQKKLIELQAGKK--------SLE 170
            K R+E +  Q+  E         +   E+ +  +E ++++L   Q   K         LE
Sbjct: 1772 KFREEEQLRQEREEQQLRSQESDRKFREEEQLRQEREEQQLRPQQRDGKYRWEEEQLQLE 1831

Query: 171  DQVEMLRTVK------EEAEKPEREAKEQHQKLWEEQLAAAKAQQEQELAADAFKELDDD 224
            +Q + LR  +      EE    + +++ + Q+LW+E+    + ++E++L  +  +    +
Sbjct: 1832 EQEQRLRQERDRQYRAEEQFATQEKSRREEQELWQEEEQKRRQERERKLREEHIRRQQKE 1891

Query: 225  MDGTVSVTELQTHPELDTDGDGALSE 250
                  V E+++    +  G G L E
Sbjct: 1892 EQRHRQVGEIKSQ---EGKGHGRLLE 1914


>gi|24307879 dynein, cytoplasmic 1, intermediate chain 2 [Homo
           sapiens]
          Length = 638

 Score = 55.5 bits (132), Expect = 1e-07
 Identities = 52/253 (20%), Positives = 105/253 (41%), Gaps = 26/253 (10%)

Query: 166 KKSLEDQVEMLRTVKEEAEKPEREAKEQHQKLWEEQLAAAKAQQEQELAADAFKELDDDM 225
           K  LE + + L  ++EE ++ E E K++     +E +A  + + + E      + L   M
Sbjct: 8   KAELERKKQRLAQIREEKKRKEEERKKKETDQKKEAVAPVQEESDLEKKRREAEALLQSM 67

Query: 226 ----DGTVSVTELQTHPELDTDGDGALSEAEAQALLSGDTQTDATSFYDRVWAAIRDKYR 281
               +  +  +E    P +        + +EA +  SGD    + + +     ++   + 
Sbjct: 68  GLTPESPIVFSEYWVPPPMSPSSKSVSTPSEAGSQDSGDGAVGSRTLHWDTDPSVLQLHS 127

Query: 282 SEALP-----------TDLPAPSAPDLTEPKEEQPPVPSSPTEEEEEEE---------EE 321
              L            T +  P    +T  KE Q PV + P E+EEE++         E 
Sbjct: 128 DSDLGRGPIKLGMAKITQVDFPPREIVTYTKETQTPVMAQPKEDEEEDDDVVAPKPPIEP 187

Query: 322 EEEEAEEEEEEEDSEEAPPPLSPPQPASPAEEDKMPPYDEQTQAFIDAA--QEARNKFEE 379
           EEE+  +++EE DS+  P  L+  +       ++   + + +   ++ A  ++    F+ 
Sbjct: 188 EEEKTLKKDEENDSKAPPHELTEEEKQQILHSEEFLSFFDHSTRIVERALSEQINIFFDY 247

Query: 380 AERSLKDMEESIR 392
           + R L+D E  I+
Sbjct: 248 SGRDLEDKEGEIQ 260


>gi|222446603 golgi autoantigen, golgin subfamily a-like [Homo
           sapiens]
          Length = 668

 Score = 55.1 bits (131), Expect = 2e-07
 Identities = 59/293 (20%), Positives = 126/293 (43%), Gaps = 19/293 (6%)

Query: 117 KEKGRKERESLQQMAEVTREGFRLKKILIEDWKKARE------EKQKKLIELQAGKKSLE 170
           +EK R++ E +++  E  R   R ++++ E  +K R       EK++K+  L+   + + 
Sbjct: 320 EEKIREQEEKIREQEEKMR---RQEEMMWEKEEKMRRQEEMMWEKEEKMRRLE---EMMW 373

Query: 171 DQVEMLRTVKEEAEKPEREAKEQHQKLWEEQLAAAKAQQEQELAADAFKELDDDMDGTVS 230
           ++ E +R ++E+  + E+  +++ ++  EE++   + +QEQE      +E   + +  + 
Sbjct: 374 EKEEKIRELEEKMHEQEKIREQEEKRQEEEKIREQEKRQEQEAKMWRQEEKIREQEEKIR 433

Query: 231 VTE--LQTHPELDTDGDGALSEAEAQALLSGDTQTDATSFYDRVWAAI-----RDKYRSE 283
             E  +    E   + +    E + Q       Q +     + +W        ++K R +
Sbjct: 434 EQEKKMWRQEEKIHEQEKIREEEKRQEQEEMWRQEEKIREQEEIWRQKEKMHEQEKIRKQ 493

Query: 284 ALPTDLPAPSAPDLTEPKEEQPPVPSSPTEEEEEEEEEEEEEAEEEEEEEDSEEAPPPLS 343
                       D  E   EQ        E+  E+EE+  E+ E+  E+E+  +      
Sbjct: 494 EEKVWRQEEKMHDQEEKIREQEEKMWRQEEKIREQEEKIREQEEKIREQEEMMQEQEEKM 553

Query: 344 PPQPASPAEEDKMPPYDEQTQAFIDAAQEARNKFEEAERSLKDMEESIRNLEQ 396
             Q     E++KM   +E+ +   +  +E + K  E E  + + EE IR  E+
Sbjct: 554 GEQEEKMQEQEKMRRQEEKIREQEEKIREQKEKIREQEEKIWEQEEKIREQEE 606



 Score = 54.7 bits (130), Expect = 2e-07
 Identities = 56/291 (19%), Positives = 126/291 (43%), Gaps = 18/291 (6%)

Query: 117 KEKGRKERESLQQMAEVTREGFRLKKILIEDWK-KAREEKQKKLIELQAGKKSLEDQVEM 175
           +EK R+  E + +  E  RE   L++ + E  K + +EEK+++  +++  +K  E + +M
Sbjct: 362 EEKMRRLEEMMWEKEEKIRE---LEEKMHEQEKIREQEEKRQEEEKIREQEKRQEQEAKM 418

Query: 176 LRTVKEEAEKPEREAKEQHQKLW--------EEQLAAAKAQQEQELAADAFKELDDDMDG 227
            R  +E+  + E + +EQ +K+W        +E++   + +QEQE      +++ +  + 
Sbjct: 419 WRQ-EEKIREQEEKIREQEKKMWRQEEKIHEQEKIREEEKRQEQEEMWRQEEKIREQEEI 477

Query: 228 TVSVTELQTHPELDTDGDGALSEAEAQALLSGDTQTDATSFYDRVWAAIRDKYRSEALPT 287
                ++    ++    +    + E       D +       +++W    +K R +    
Sbjct: 478 WRQKEKMHEQEKIRKQEEKVWRQEEKMH----DQEEKIREQEEKMWRQ-EEKIREQEEKI 532

Query: 288 DLPAPSAPDLTEPKEEQPPVPSSPTEEEEEEEEEEEEEAEEEEEEEDSEEAPPPLSPPQP 347
                   +  E  +EQ        E+ +E+E+   +E +  E+EE   E    +   + 
Sbjct: 533 REQEEKIREQEEMMQEQEEKMGEQEEKMQEQEKMRRQEEKIREQEEKIREQKEKIREQEE 592

Query: 348 ASPAEEDKMPPYDEQTQAFIDAAQEARNKFEEAERSLKDMEESIRNLEQEI 398
               +E+K+   +E  Q   +   E   K  E E  +++ EE +R  E+++
Sbjct: 593 KIWEQEEKIREQEEMMQEQEEKMWEQEEKMCEQEEKMQEQEEKMRRQEEKM 643



 Score = 54.3 bits (129), Expect = 3e-07
 Identities = 55/321 (17%), Positives = 128/321 (39%), Gaps = 22/321 (6%)

Query: 122 KERESLQQMAEVTREGFRLKKILIEDWKKAREEKQKKLIELQAGKKSLEDQVEMLRTVKE 181
           +E E   ++ +   E    ++  I++W++  +E+++K+ E +   + + +Q E +R  +E
Sbjct: 286 EENELWNRLNQQQEEKMWRQEEKIQEWEEKIQEQEEKIREQE---EKIREQEEKMRRQEE 342

Query: 182 EAEKPEREAKEQHQKLWEEQLAAAKAQQEQELAADAFKELDDDMDGTVSVTELQTHPELD 241
              + E + + Q + +WE++    + ++      +  +EL++ M     + E Q     +
Sbjct: 343 MMWEKEEKMRRQEEMMWEKEEKMRRLEEMMWEKEEKIRELEEKMHEQEKIRE-QEEKRQE 401

Query: 242 TDGDGALSEAEAQALLSGDTQTDATSFYDRVWAAIRDKYRSEALPTDLPAPSAPDLTEPK 301
            +      + + Q       +       +++    +  +R E               E  
Sbjct: 402 EEKIREQEKRQEQEAKMWRQEEKIREQEEKIREQEKKMWRQE---------------EKI 446

Query: 302 EEQPPVPSSPTEEEEEEEEEEEEEAEEEEE---EEDSEEAPPPLSPPQPASPAEEDKMPP 358
            EQ  +      +E+EE   +EE+  E+EE   +++       +   +     +E+KM  
Sbjct: 447 HEQEKIREEEKRQEQEEMWRQEEKIREQEEIWRQKEKMHEQEKIRKQEEKVWRQEEKMHD 506

Query: 359 YDEQTQAFIDAAQEARNKFEEAERSLKDMEESIRNLEQEISFDFGPNGEFAYLYSQCYEL 418
            +E+ +   +       K  E E  +++ EE IR  E+ +       GE      +  ++
Sbjct: 507 QEEKIREQEEKMWRQEEKIREQEEKIREQEEKIREQEEMMQEQEEKMGEQEEKMQEQEKM 566

Query: 419 TTNEYVYRLCPFKLVSQKPKL 439
              E   R    K+  QK K+
Sbjct: 567 RRQEEKIREQEEKIREQKEKI 587



 Score = 44.3 bits (103), Expect = 3e-04
 Identities = 46/257 (17%), Positives = 116/257 (45%), Gaps = 40/257 (15%)

Query: 113 ENTCKEKGRKERESLQQMAEVTREGFRL--KKILIEDWKKAREEKQKKLIELQAGKKSLE 170
           E   +E+ R+E+E + +  E  RE   +  +K  + + +K R++++K    +   ++ + 
Sbjct: 450 EKIREEEKRQEQEEMWRQEEKIREQEEIWRQKEKMHEQEKIRKQEEK----VWRQEEKMH 505

Query: 171 DQVEMLRTVKEEAEKPEREAKEQHQKLWEEQLAAAKAQQEQELAADAFKELDDDMDGTVS 230
           DQ E +R  +E+  + E + +EQ +K+ E++    K ++++E+  +  +++ +  +    
Sbjct: 506 DQEEKIREQEEKMWRQEEKIREQEEKIREQE---EKIREQEEMMQEQEEKMGEQEEKMQE 562

Query: 231 VTELQTHPELDTDGDGALSEAEAQALLSGDTQTDATSFYDRVWAAIRDKYRSEALPTDLP 290
             +++   E   + +  + E + +               +++W    +K R +       
Sbjct: 563 QEKMRRQEEKIREQEEKIREQKEKI----------REQEEKIWEQ-EEKIREQE------ 605

Query: 291 APSAPDLTEPKEEQPPVPSSPTEEEEEEEEEEEEEAEEEEEEEDSEEAPPPLSPPQPASP 350
                ++ + +EE+         E+EE+ +E+EE+   +EE+   +E             
Sbjct: 606 -----EMMQEQEEKMWEQEEKMCEQEEKMQEQEEKMRRQEEKMWEQEV---------RLR 651

Query: 351 AEEDKMPPYDEQTQAFI 367
            +E+KM  + E  +A I
Sbjct: 652 QQEEKMQEHQEHLEAAI 668


>gi|157738649 neurofilament, medium polypeptide 150kDa isoform 1
           [Homo sapiens]
          Length = 916

 Score = 55.1 bits (131), Expect = 2e-07
 Identities = 74/298 (24%), Positives = 128/298 (42%), Gaps = 42/298 (14%)

Query: 111 ICENTCKEKGRKERESLQQMAEVTREGFRLKKILIEDWKKAREEKQKK--LIELQAGKKS 168
           I E T  E  + E E  + +  +T E   L   + E+ K+A EEK+++    E +   K 
Sbjct: 456 IIEETKVEDEKSEME--EALTAITEE---LAVSMKEEKKEAAEEKEEEPEAEEEEVAAKK 510

Query: 169 LEDQVEMLRTVKEEAEKPEREAKEQHQKLWEEQLAAAKAQQEQELAADAFKELDDDMDGT 228
              +       +EE EK E E +E+     EE+   AK+ Q +E  ++         +G+
Sbjct: 511 SPVKATAPEVKEEEGEKEEEEGQEEE----EEEDEGAKSDQAEEGGSEK--------EGS 558

Query: 229 VSVTELQTHPELDTDGDGALSEAEAQALLSGDTQTDATSFYDRVWAAIRDKYRSEALPTD 288
            S  E     E +T+ +    EAEA+     + +++  +  + + A  + +   +A    
Sbjct: 559 -SEKEEGEQEEGETEAEAEGEEAEAKEEKKVEEKSEEVATKEELVADAKVEKPEKAKS-- 615

Query: 289 LPAPSAPDLTEPKEEQP----------PVPSSPTEEE------EEEEEEEEEEAEEEEEE 332
            P P +P   + K   P          PVP SP EE+      +   EE+ +    +   
Sbjct: 616 -PVPKSPVEEKGKSPVPKSPVEEKGKSPVPKSPVEEKGKSPVPKSPVEEKGKSPVSKSPV 674

Query: 333 EDSEEAPPPLSPPQPA-SPAEEDKMPPYDEQTQAFIDAAQEARNKFEEAERSLKDMEE 389
           E+  ++P P SP + A S AE  K    +E+ +   +A +E   K E+ E   KD+ E
Sbjct: 675 EEKAKSPVPKSPVEEAKSKAEVGKGEQKEEEEKEVKEAPKE--EKVEKKEEKPKDVPE 730



 Score = 49.7 bits (117), Expect = 7e-06
 Identities = 69/310 (22%), Positives = 129/310 (41%), Gaps = 39/310 (12%)

Query: 127 LQQMAEVTREGFRLKKILIEDWKKAREEKQKKLIELQAGKKSLEDQVEM--------LRT 178
           L + AE  +E  R  K  I ++++  + K  +L  ++  K+SLE Q+          L +
Sbjct: 299 LTEAAEQNKEAIRSAKEEIAEYRRQLQSKSIELESVRGTKESLERQLSDIEERHNHDLSS 358

Query: 179 VKEEAEKPEREAK------EQHQKLWEEQLAAAKAQQEQELAADAFKELDDDMDGTV--S 230
            ++  ++ E E +       +H + +++ L    A   +  A     E ++    T   S
Sbjct: 359 YQDTIQQLENELRGTKWEMARHLREYQDLLNVKMALDIEIAAYRKLLEGEETRFSTFAGS 418

Query: 231 VT-ELQTH-PELDTDGDGALSEAEA----------QALLSGDTQTDATSFYDRVWAAIRD 278
           +T  L TH P +         + EA          + ++      D  S  +    AI +
Sbjct: 419 ITGPLYTHRPPITISSKIQKPKVEAPKLKVQHKFVEEIIEETKVEDEKSEMEEALTAITE 478

Query: 279 KY-------RSEALPTDLPAPSAPDLTEPKEEQPPVPSSPTEEEEEEEEEEEEEAEEEEE 331
           +        + EA       P A +     ++ P   ++P  +EEE E+EEEE  EEEEE
Sbjct: 479 ELAVSMKEEKKEAAEEKEEEPEAEEEEVAAKKSPVKATAPEVKEEEGEKEEEEGQEEEEE 538

Query: 332 EED---SEEAPPPLSPPQPASPAEEDKMPPYDEQTQAFIDAAQ-EARNKFEEAERSLKDM 387
           E++   S++A    S  + +S  EE +    + + +A  + A+ +   K EE    +   
Sbjct: 539 EDEGAKSDQAEEGGSEKEGSSEKEEGEQEEGETEAEAEGEEAEAKEEKKVEEKSEEVATK 598

Query: 388 EESIRNLEQE 397
           EE + + + E
Sbjct: 599 EELVADAKVE 608



 Score = 49.7 bits (117), Expect = 7e-06
 Identities = 66/277 (23%), Positives = 112/277 (40%), Gaps = 59/277 (21%)

Query: 117 KEKGRKERESLQQMAEVTREGFRLKKILI---------EDWKKAREEKQKKLIELQAGKK 167
           KE+ ++  E  ++  E   E    KK  +         E+ +K  EE Q++  E   G K
Sbjct: 485 KEEKKEAAEEKEEEPEAEEEEVAAKKSPVKATAPEVKEEEGEKEEEEGQEEEEEEDEGAK 544

Query: 168 SLEDQVEMLRTVKEEAEKPEREAKEQHQKLWEEQLAAAKAQQEQELAADAFKELDDDMDG 227
           S  DQ E   + KE + + E   +E+ +   E +   A+A++E+++   +          
Sbjct: 545 S--DQAEEGGSEKEGSSEKEEGEQEEGETEAEAEGEEAEAKEEKKVEEKS---------- 592

Query: 228 TVSVTELQTHPELDTDGDGALSEAEAQALLSGDTQTDATSFYDRVWAAIRDKYRSEALPT 287
                E+ T  EL  D      E     +     +    S   +  + + +K +S    +
Sbjct: 593 ----EEVATKEELVADAKVEKPEKAKSPVPKSPVEEKGKSPVPK--SPVEEKGKSPVPKS 646

Query: 288 DL------PAPSAPDLTEPKEEQP------------PVPSSPTEE-----------EEEE 318
            +      P P +P   E K + P            PVP SP EE           ++EE
Sbjct: 647 PVEEKGKSPVPKSP--VEEKGKSPVSKSPVEEKAKSPVPKSPVEEAKSKAEVGKGEQKEE 704

Query: 319 EEEEEEEAEEEEEEEDSEEAPPPLSPPQPA-SPAEED 354
           EE+E +EA +EE+ E  EE P  +   + A SP +E+
Sbjct: 705 EEKEVKEAPKEEKVEKKEEKPKDVPEKKKAESPVKEE 741



 Score = 35.8 bits (81), Expect = 0.099
 Identities = 54/265 (20%), Positives = 103/265 (38%), Gaps = 27/265 (10%)

Query: 146 EDWKKAREEKQKKLIELQAGKKSLEDQVEMLRTVKEEAEKPEREAKEQHQKLWEEQLAAA 205
           E+W K R  K  +         + E   E +R+ KEE  +  R+ + +  +L  E +   
Sbjct: 289 EEWFKCRYAKLTE---------AAEQNKEAIRSAKEEIAEYRRQLQSKSIEL--ESVRGT 337

Query: 206 KAQQEQELAADAFKELDDDMDGTVSVTELQTHPELDTDGDGALSEAEAQALLSGDTQTDA 265
           K   E++L+ D  +  + D+       +   +    T  + A    E Q LL+     D 
Sbjct: 338 KESLERQLS-DIEERHNHDLSSYQDTIQQLENELRGTKWEMARHLREYQDLLNVKMALDI 396

Query: 266 T-SFYDRVWAAIRDKYRSEA--LPTDLPAPSAPDLTEPKEEQPPVPSSPTEEEEEEEEEE 322
             + Y ++      ++ + A  +   L     P     K ++P V +   + + +  EE 
Sbjct: 397 EIAAYRKLLEGEETRFSTFAGSITGPLYTHRPPITISSKIQKPKVEAPKLKVQHKFVEEI 456

Query: 323 EEEAEEEEEEEDSEEAPPPLSPPQPASPAEEDKMPPYDEQTQAFIDAAQEARNKFEEAER 382
            EE + E+E+ + EEA   ++     S  EE K            +AA+E   + E  E 
Sbjct: 457 IEETKVEDEKSEMEEALTAITEELAVSMKEEKK------------EAAEEKEEEPEAEEE 504

Query: 383 SLKDMEESIRNLEQEISFDFGPNGE 407
            +   +  ++    E+  + G   E
Sbjct: 505 EVAAKKSPVKATAPEVKEEEGEKEE 529


>gi|157738641 neurofilament, medium polypeptide 150kDa isoform 2
           [Homo sapiens]
          Length = 540

 Score = 55.1 bits (131), Expect = 2e-07
 Identities = 74/298 (24%), Positives = 128/298 (42%), Gaps = 42/298 (14%)

Query: 111 ICENTCKEKGRKERESLQQMAEVTREGFRLKKILIEDWKKAREEKQKK--LIELQAGKKS 168
           I E T  E  + E E  + +  +T E   L   + E+ K+A EEK+++    E +   K 
Sbjct: 80  IIEETKVEDEKSEME--EALTAITEE---LAVSMKEEKKEAAEEKEEEPEAEEEEVAAKK 134

Query: 169 LEDQVEMLRTVKEEAEKPEREAKEQHQKLWEEQLAAAKAQQEQELAADAFKELDDDMDGT 228
              +       +EE EK E E +E+     EE+   AK+ Q +E  ++         +G+
Sbjct: 135 SPVKATAPEVKEEEGEKEEEEGQEEE----EEEDEGAKSDQAEEGGSEK--------EGS 182

Query: 229 VSVTELQTHPELDTDGDGALSEAEAQALLSGDTQTDATSFYDRVWAAIRDKYRSEALPTD 288
            S  E     E +T+ +    EAEA+     + +++  +  + + A  + +   +A    
Sbjct: 183 -SEKEEGEQEEGETEAEAEGEEAEAKEEKKVEEKSEEVATKEELVADAKVEKPEKAKS-- 239

Query: 289 LPAPSAPDLTEPKEEQP----------PVPSSPTEEE------EEEEEEEEEEAEEEEEE 332
            P P +P   + K   P          PVP SP EE+      +   EE+ +    +   
Sbjct: 240 -PVPKSPVEEKGKSPVPKSPVEEKGKSPVPKSPVEEKGKSPVPKSPVEEKGKSPVSKSPV 298

Query: 333 EDSEEAPPPLSPPQPA-SPAEEDKMPPYDEQTQAFIDAAQEARNKFEEAERSLKDMEE 389
           E+  ++P P SP + A S AE  K    +E+ +   +A +E   K E+ E   KD+ E
Sbjct: 299 EEKAKSPVPKSPVEEAKSKAEVGKGEQKEEEEKEVKEAPKE--EKVEKKEEKPKDVPE 354



 Score = 49.7 bits (117), Expect = 7e-06
 Identities = 66/277 (23%), Positives = 112/277 (40%), Gaps = 59/277 (21%)

Query: 117 KEKGRKERESLQQMAEVTREGFRLKKILI---------EDWKKAREEKQKKLIELQAGKK 167
           KE+ ++  E  ++  E   E    KK  +         E+ +K  EE Q++  E   G K
Sbjct: 109 KEEKKEAAEEKEEEPEAEEEEVAAKKSPVKATAPEVKEEEGEKEEEEGQEEEEEEDEGAK 168

Query: 168 SLEDQVEMLRTVKEEAEKPEREAKEQHQKLWEEQLAAAKAQQEQELAADAFKELDDDMDG 227
           S  DQ E   + KE + + E   +E+ +   E +   A+A++E+++   +          
Sbjct: 169 S--DQAEEGGSEKEGSSEKEEGEQEEGETEAEAEGEEAEAKEEKKVEEKS---------- 216

Query: 228 TVSVTELQTHPELDTDGDGALSEAEAQALLSGDTQTDATSFYDRVWAAIRDKYRSEALPT 287
                E+ T  EL  D      E     +     +    S   +  + + +K +S    +
Sbjct: 217 ----EEVATKEELVADAKVEKPEKAKSPVPKSPVEEKGKSPVPK--SPVEEKGKSPVPKS 270

Query: 288 DL------PAPSAPDLTEPKEEQP------------PVPSSPTEE-----------EEEE 318
            +      P P +P   E K + P            PVP SP EE           ++EE
Sbjct: 271 PVEEKGKSPVPKSP--VEEKGKSPVSKSPVEEKAKSPVPKSPVEEAKSKAEVGKGEQKEE 328

Query: 319 EEEEEEEAEEEEEEEDSEEAPPPLSPPQPA-SPAEED 354
           EE+E +EA +EE+ E  EE P  +   + A SP +E+
Sbjct: 329 EEKEVKEAPKEEKVEKKEEKPKDVPEKKKAESPVKEE 365



 Score = 46.6 bits (109), Expect = 6e-05
 Identities = 34/121 (28%), Positives = 59/121 (48%), Gaps = 4/121 (3%)

Query: 281 RSEALPTDLPAPSAPDLTEPKEEQPPVPSSPTEEEEEEEEEEEEEAEEEEEEED---SEE 337
           + EA       P A +     ++ P   ++P  +EEE E+EEEE  EEEEEE++   S++
Sbjct: 112 KKEAAEEKEEEPEAEEEEVAAKKSPVKATAPEVKEEEGEKEEEEGQEEEEEEDEGAKSDQ 171

Query: 338 APPPLSPPQPASPAEEDKMPPYDEQTQAFIDAAQ-EARNKFEEAERSLKDMEESIRNLEQ 396
           A    S  + +S  EE +    + + +A  + A+ +   K EE    +   EE + + + 
Sbjct: 172 AEEGGSEKEGSSEKEEGEQEEGETEAEAEGEEAEAKEEKKVEEKSEEVATKEELVADAKV 231

Query: 397 E 397
           E
Sbjct: 232 E 232



 Score = 44.3 bits (103), Expect = 3e-04
 Identities = 29/114 (25%), Positives = 48/114 (42%), Gaps = 10/114 (8%)

Query: 296 DLTEPKEEQPPV----------PSSPTEEEEEEEEEEEEEAEEEEEEEDSEEAPPPLSPP 345
           +  E KEE+P            P   T  E +EEE E+EE E +EEEE+ +E        
Sbjct: 114 EAAEEKEEEPEAEEEEVAAKKSPVKATAPEVKEEEGEKEEEEGQEEEEEEDEGAKSDQAE 173

Query: 346 QPASPAEEDKMPPYDEQTQAFIDAAQEARNKFEEAERSLKDMEESIRNLEQEIS 399
           +  S  E        EQ +   +A  E      + E+ +++  E +   E+ ++
Sbjct: 174 EGGSEKEGSSEKEEGEQEEGETEAEAEGEEAEAKEEKKVEEKSEEVATKEELVA 227



 Score = 36.2 bits (82), Expect = 0.076
 Identities = 26/102 (25%), Positives = 47/102 (46%), Gaps = 3/102 (2%)

Query: 299 EPKEEQPPVPSSPTEE---EEEEEEEEEEEAEEEEEEEDSEEAPPPLSPPQPASPAEEDK 355
           + K E     ++ TEE     +EE++E  E +EEE E + EE     SP +  +P  +++
Sbjct: 88  DEKSEMEEALTAITEELAVSMKEEKKEAAEEKEEEPEAEEEEVAAKKSPVKATAPEVKEE 147

Query: 356 MPPYDEQTQAFIDAAQEARNKFEEAERSLKDMEESIRNLEQE 397
               +E+     +  ++   K ++AE    + E S    E E
Sbjct: 148 EGEKEEEEGQEEEEEEDEGAKSDQAEEGGSEKEGSSEKEEGE 189



 Score = 30.0 bits (66), Expect = 5.4
 Identities = 25/113 (22%), Positives = 46/113 (40%), Gaps = 12/113 (10%)

Query: 295 PDLTEPKEEQPPVPSSPTEEEEEEEEEEEEEAEEEEEEEDSEEAPPPLSPPQPASPAEED 354
           P     K ++P V +   + + +  EE  EE + E+E+ + EEA   ++     S  EE 
Sbjct: 53  PITISSKIQKPKVEAPKLKVQHKFVEEIIEETKVEDEKSEMEEALTAITEELAVSMKEEK 112

Query: 355 KMPPYDEQTQAFIDAAQEARNKFEEAERSLKDMEESIRNLEQEISFDFGPNGE 407
           K            +AA+E   + E  E  +   +  ++    E+  + G   E
Sbjct: 113 K------------EAAEEKEEEPEAEEEEVAAKKSPVKATAPEVKEEEGEKEE 153


>gi|55741709 RNA binding motif protein 25 [Homo sapiens]
          Length = 843

 Score = 54.3 bits (129), Expect = 3e-07
 Identities = 68/278 (24%), Positives = 113/278 (40%), Gaps = 54/278 (19%)

Query: 117 KEKGRKERESLQQMAEVTREGFRLKKILIEDWKKAREEKQKKLIELQAGKKSLEDQVEML 176
           +EK R      ++  E  RE  R ++    + ++ RE ++++  E    +   ED+ +  
Sbjct: 385 REKSRDRERERERERERERERERERE---REREREREREREREREKDKKRDREEDEEDAY 441

Query: 177 RTVKEEAEKPEREAKEQHQ-KLWE----------EQLAAAKAQQEQELAADA------FK 219
              K E +  E+EA  Q + K WE          E+ A  + ++ +E+A +A       +
Sbjct: 442 ERRKLERKLREKEAAYQERLKNWEIRERKKTREYEKEAEREEERRREMAKEAKRLKEFLE 501

Query: 220 ELDDDMD------GTVSVTELQTHPELDTDGDGALSEAEAQALLSGDTQTDATSFYDRVW 273
           + DDD D      G+     L+   E + + D    + E + L                 
Sbjct: 502 DYDDDRDDPKYYRGSALQKRLRDR-EKEMEADERDRKREKEEL----------------- 543

Query: 274 AAIRDKYRSEALPTDLPAPSAPDLTEPKEEQPPVPSSPTEEEEEEEEEEEEEAEEE--EE 331
             IR +  +E  P         +    +  QP +   P  EEEEEE++E+EE  EE  EE
Sbjct: 544 EEIRQRLLAEGHPDPDAELQRMEQEAERRRQPQIKQEPESEEEEEEKQEKEEKREEPMEE 603

Query: 332 EEDSEEAP------PPLSPPQPASPAEEDKMP--PYDE 361
           EE+ E+ P       P+S     S A  +  P  P DE
Sbjct: 604 EEEPEQKPCLKPTLRPISSAPSVSSASGNATPNTPGDE 641



 Score = 44.3 bits (103), Expect = 3e-04
 Identities = 51/245 (20%), Positives = 100/245 (40%), Gaps = 32/245 (13%)

Query: 158 KLIELQAGKKSLEDQ-VEMLRTVKEEAEKPEREAKEQHQKLWEEQLAAAKAQQEQELAAD 216
           K +E + GKK  E Q +E  R  +E   + ERE +E+ ++   E+      ++E+E   +
Sbjct: 289 KKLEEEKGKKEKERQEIEKERRERERERERERERRERERERERER------EREKEKERE 342

Query: 217 AFKELDDDMDGTVSVTELQTHPELDTDGDGALSEAEAQALLSGDTQTDATSFYDRVWAAI 276
             +E D D D T    +     E D D D      E  +  + D         DR     
Sbjct: 343 RERERDRDRDRT-KERDRDRDRERDRDRD-----RERSSDRNKDRSRSREKSRDRERERE 396

Query: 277 RDKYRSEALPTDLPAPSAPDLTEPKEEQPPVPSSPTEEEEEEEEEEEEEAEEEEEEEDSE 336
           R++ R                 E + E+        E E E E E++++ + EE+EED+ 
Sbjct: 397 RERERER---------------EREREREREREREREREREREREKDKKRDREEDEEDAY 441

Query: 337 EAPPPLSPPQPASPAEEDKMPPYD----EQTQAFIDAAQEARNKFEEAERSLKDMEESIR 392
           E        +    A ++++  ++    ++T+ +   A+    +  E  +  K ++E + 
Sbjct: 442 ERRKLERKLREKEAAYQERLKNWEIRERKKTREYEKEAEREEERRREMAKEAKRLKEFLE 501

Query: 393 NLEQE 397
           + + +
Sbjct: 502 DYDDD 506



 Score = 36.6 bits (83), Expect = 0.058
 Identities = 51/235 (21%), Positives = 86/235 (36%), Gaps = 19/235 (8%)

Query: 173 VEMLRTVKEEAEKPEREAKEQHQKLWEEQLAAAKAQQEQELAADAFKELDDDMDGTVSVT 232
           +EM    ++   +   + ++ H+KL EE+    K +QE E      +E + + +      
Sbjct: 267 IEMEEDKRDLISREISKFRDTHKKLEEEKGKKEKERQEIEKER---RERERERERERERR 323

Query: 233 ELQTHPELDTDGDGALSEAEAQALLSGDTQTDATSFYDRVWAAIRDKYRSEALPTDLPAP 292
           E +   E + + +    E E +     D   D T   DR     RD+ R     +D    
Sbjct: 324 ERERERERERERE---KEKERERERERDRDRDRTKERDRDRDRERDRDRDRERSSDRNKD 380

Query: 293 SAPDLTEPKE-EQPPVPSSPTEEEEEEEEEEEEEAEEEEEEEDSEEAPPPLSPPQPASPA 351
            +    + ++ E+        E E E E E E E E E E E   E        +    A
Sbjct: 381 RSRSREKSRDREREREREREREREREREREREREREREREREREREKDKKRDREEDEEDA 440

Query: 352 EE---------DKMPPYDEQTQAFIDAAQEARNKFEEAERSLKDMEESIRNLEQE 397
            E         +K   Y E+ + +       R K  E E+  +  EE  R + +E
Sbjct: 441 YERRKLERKLREKEAAYQERLKNW---EIRERKKTREYEKEAEREEERRREMAKE 492



 Score = 32.7 bits (73), Expect = 0.84
 Identities = 20/77 (25%), Positives = 36/77 (46%)

Query: 313 EEEEEEEEEEEEEAEEEEEEEDSEEAPPPLSPPQPASPAEEDKMPPYDEQTQAFIDAAQE 372
           E +E + + E+EE EE  +   +E  P P +  Q      E +  P  +Q     +  +E
Sbjct: 530 EADERDRKREKEELEEIRQRLLAEGHPDPDAELQRMEQEAERRRQPQIKQEPESEEEEEE 589

Query: 373 ARNKFEEAERSLKDMEE 389
            + K E+ E  +++ EE
Sbjct: 590 KQEKEEKREEPMEEEEE 606


>gi|118600967 shroom family member 4 [Homo sapiens]
          Length = 1493

 Score = 53.5 bits (127), Expect = 5e-07
 Identities = 30/67 (44%), Positives = 36/67 (53%), Gaps = 7/67 (10%)

Query: 281  RSEALPTDLPAPSAPD-------LTEPKEEQPPVPSSPTEEEEEEEEEEEEEAEEEEEEE 333
            R +A P   P P   +         + K++Q        EEEEEEEEEEEEE EEEE EE
Sbjct: 1095 RKKAFPPPRPPPPNWEKYRLFRAAQQQKQQQQQQKQQEEEEEEEEEEEEEEEEEEEEAEE 1154

Query: 334  DSEEAPP 340
            + EE PP
Sbjct: 1155 EEEELPP 1161



 Score = 37.0 bits (84), Expect = 0.045
 Identities = 18/63 (28%), Positives = 33/63 (52%), Gaps = 8/63 (12%)

Query: 305  PPVPSSPTEE--------EEEEEEEEEEEAEEEEEEEDSEEAPPPLSPPQPASPAEEDKM 356
            PP P  P  E        +++++++++++ +EEEEEE+ EE        + A   EE+  
Sbjct: 1101 PPRPPPPNWEKYRLFRAAQQQKQQQQQQKQQEEEEEEEEEEEEEEEEEEEEAEEEEEELP 1160

Query: 357  PPY 359
            P Y
Sbjct: 1161 PQY 1163



 Score = 34.3 bits (77), Expect = 0.29
 Identities = 23/57 (40%), Positives = 26/57 (45%), Gaps = 8/57 (14%)

Query: 301  KEEQPPVPSSPTEEEEEEEEEEEEEAEEEEEEEDSEEA--------PPPLSPPQPAS 349
            +EE+        EEEEEEEEE EEE EE   +  S E            L  PQP S
Sbjct: 1131 QEEEEEEEEEEEEEEEEEEEEAEEEEEELPPQYFSSETSGSCALNPEEVLEQPQPLS 1187


>gi|239745095 PREDICTED: hypothetical protein LOC645202 [Homo
           sapiens]
          Length = 570

 Score = 53.5 bits (127), Expect = 5e-07
 Identities = 42/255 (16%), Positives = 107/255 (41%), Gaps = 19/255 (7%)

Query: 146 EDWKKAREEKQKKLIELQAGKKSLEDQVEMLRTVKEEAEKPEREAKEQHQKLWEEQLAAA 205
           E W +  +++++K+   +   + ++++ E ++  +E+  + E + + Q + +WE++    
Sbjct: 277 ELWNRLNQQQEEKMWRQE---EKIQEREEKIQEQEEKIREQEEKMRRQEEMMWEKEEKMR 333

Query: 206 KAQQEQELAADAFKELDDDMDGTVSVTELQTHPELDTDGDGALSEAEAQALLSGDTQTDA 265
           + ++      +  +EL++ M     + E +   +            E + +   + + + 
Sbjct: 334 RQEEMMWEKEEKIRELEEKMHEQEKIREQEEKRQ------------EEEKIREQEKRQEQ 381

Query: 266 TSFYDRVWAAIRDKYRSEALPTDLPAPSAPDLTEPKEEQPPVPSSPTEEEEEEEEEEEEE 325
            +   R    IR++        ++       + E +E+         E+EE+   +EE+ 
Sbjct: 382 EAKMWRQEEKIREQEEKIREQEEMMQEQEEKMGEQEEKMWEQEEEMQEQEEKMRRQEEKI 441

Query: 326 AEEE----EEEEDSEEAPPPLSPPQPASPAEEDKMPPYDEQTQAFIDAAQEARNKFEEAE 381
            E+E    E+EE   E    +   +     +E KM   + + Q   +  +    K  E E
Sbjct: 442 REQEKKIREQEEKIREQEEMMQEQEEKMGEQEGKMCEQEAKMQEQEEKMRRQEEKIREQE 501

Query: 382 RSLKDMEESIRNLEQ 396
           + +++ EE IR  E+
Sbjct: 502 KKIREQEEKIREQEE 516



 Score = 52.4 bits (124), Expect = 1e-06
 Identities = 52/288 (18%), Positives = 130/288 (45%), Gaps = 13/288 (4%)

Query: 117 KEKGRKERESLQQMAEVTREGFRLKKILIEDWKKAREEKQ--KKLIELQAGKKSLEDQVE 174
           +EK  ++ E +Q+  E  +E  + +KI  ++ K  R+E+   +K  +++  ++ + ++ E
Sbjct: 287 EEKMWRQEEKIQEREEKIQE--QEEKIREQEEKMRRQEEMMWEKEEKMRRQEEMMWEKEE 344

Query: 175 MLRTVKEEAEKPEREAKEQHQKLWEEQLAAAKAQQEQELAADAFKELDDDMDGTVSVTEL 234
            +R ++E+  + E+  +++ ++  EE++   + +QEQE  A  +++ +   +    + E 
Sbjct: 345 KIRELEEKMHEQEKIREQEEKRQEEEKIREQEKRQEQE--AKMWRQEEKIREQEEKIREQ 402

Query: 235 QTHPELDTDGDGALSEAEAQALLSGDTQTDATSFYDRVWAAIRDKYRSEALPTDLPAPSA 294
           +   E+  + +  + E E +     +   +      R    IR++ +      +      
Sbjct: 403 E---EMMQEQEEKMGEQEEKMWEQEEEMQEQEEKMRRQEEKIREQEKKIREQEEKIREQE 459

Query: 295 PDLTEPKEEQPPVPSSPTEEE----EEEEEEEEEEAEEEEEEEDSEEAPPPLSPPQPASP 350
             + E +E+         E+E    E+EE+   +E +  E+E+   E    +   +    
Sbjct: 460 EMMQEQEEKMGEQEGKMCEQEAKMQEQEEKMRRQEEKIREQEKKIREQEEKIREQEEMMQ 519

Query: 351 AEEDKMPPYDEQTQAFIDAAQEARNKFEEAERSLKDMEESIRNLEQEI 398
            +E+KM   +E+     +  QE   K    E  +++ E  +R  E+++
Sbjct: 520 EQEEKMWEQEEKMCEQEEKMQEQEEKMRRQEEKMREQEVRLRQQEEKM 567



 Score = 49.7 bits (117), Expect = 7e-06
 Identities = 57/293 (19%), Positives = 117/293 (39%), Gaps = 20/293 (6%)

Query: 115 TCKEKGRKERESLQQMAEVTREGFRLKKILIEDWKKAREEKQKKLIELQAGKKSLEDQVE 174
           T K+K  +  E L +  +          I  E+ K+   + Q+KL  +++ K  ++  V+
Sbjct: 174 TQKKKADRYIEELTKERDALSLELYRNTITDEELKEKNAKLQEKLQLVESEKSEIQLNVK 233

Query: 175 MLRTVKEEAEK--PEREAKEQHQKLWEEQLAAAKAQQEQELAADAFKELDDDMDGTVSVT 232
            L+   E A+   P+++ + +   L +E  + +   Q Q    + +  L+   +  +   
Sbjct: 234 ELKRKLERAKLLLPQQQLQAEADHLGKELQSVSAKLQAQVEENELWNRLNQQQEEKMWRQ 293

Query: 233 E--LQTHPELDTDGDGALSEAEAQALLSGDTQTDATSFYDRVWAAIRDKYRSEALPTDLP 290
           E  +Q   E   + +  + E E +     +           +W       R E +  +  
Sbjct: 294 EEKIQEREEKIQEQEEKIREQEEKMRRQEEM----------MWEKEEKMRRQEEMMWE-K 342

Query: 291 APSAPDLTEPKEEQPPVPSSPTEEEEEE-----EEEEEEEAEEEEEEEDSEEAPPPLSPP 345
                +L E   EQ  +     + +EEE     E+ +E+EA+   +EE   E    +   
Sbjct: 343 EEKIRELEEKMHEQEKIREQEEKRQEEEKIREQEKRQEQEAKMWRQEEKIREQEEKIREQ 402

Query: 346 QPASPAEEDKMPPYDEQTQAFIDAAQEARNKFEEAERSLKDMEESIRNLEQEI 398
           +     +E+KM   +E+     +  QE   K    E  +++ E+ IR  E++I
Sbjct: 403 EEMMQEQEEKMGEQEEKMWEQEEEMQEQEEKMRRQEEKIREQEKKIREQEEKI 455



 Score = 47.8 bits (112), Expect = 3e-05
 Identities = 46/229 (20%), Positives = 101/229 (44%), Gaps = 9/229 (3%)

Query: 118 EKGRKERESLQQMAEVTREGFRLKKILIEDWKKAREEKQKKLIELQAGKKSLEDQVEMLR 177
           EK  K RE  ++M E  +   + +K   E+  + +E++Q++  ++   ++ + +Q E +R
Sbjct: 341 EKEEKIRELEEKMHEQEKIREQEEKRQEEEKIREQEKRQEQEAKMWRQEEKIREQEEKIR 400

Query: 178 TVKEEAEKPEREAKEQHQKLWEE----QLAAAKAQQEQELAADAFKELDDDMDGTVSVTE 233
             +E  ++ E +  EQ +K+WE+    Q    K ++++E   +  K++ +  +      E
Sbjct: 401 EQEEMMQEQEEKMGEQEEKMWEQEEEMQEQEEKMRRQEEKIREQEKKIREQEEKIREQEE 460

Query: 234 L-QTHPELDTDGDGALSEAEAQALLSGDTQTDATSFYDRVWAAIRDKYRSEALPTDLPAP 292
           + Q   E   + +G + E EA+     +               IR++        ++   
Sbjct: 461 MMQEQEEKMGEQEGKMCEQEAKMQEQEEKMRRQEEKIREQEKKIREQEEKIREQEEMMQE 520

Query: 293 SAPDLTEPKEEQPPVPSSPTEEEE----EEEEEEEEEAEEEEEEEDSEE 337
               + E +E+         E+EE    +EE+  E+E    ++EE  +E
Sbjct: 521 QEEKMWEQEEKMCEQEEKMQEQEEKMRRQEEKMREQEVRLRQQEEKMQE 569


  Database: hs.faa
    Posted date:  Aug 4, 2009  4:42 PM
  Number of letters in database: 18,247,518
  Number of sequences in database:  37,866
  
Lambda     K      H
   0.309    0.129    0.384 

Gapped
Lambda     K      H
   0.267   0.0410    0.140 


Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Hits to DB: 25,730,827
Number of Sequences: 37866
Number of extensions: 1554361
Number of successful extensions: 66601
Number of sequences better than 10.0: 30
Number of HSP's better than 10.0 without gapping: 1413
Number of HSP's successfully gapped in prelim test: 1213
Number of HSP's that attempted gapping in prelim test: 18747
Number of HSP's gapped (non-prelim): 20188
length of query: 528
length of database: 18,247,518
effective HSP length: 107
effective length of query: 421
effective length of database: 14,195,856
effective search space: 5976455376
effective search space used: 5976455376
T: 11
A: 40
X1: 16 ( 7.1 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 42 (21.7 bits)
S2: 64 (29.3 bits)

Search results were obtained with NCBI BLAST and RefSeq entries.


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Guide to the Human Genome
Copyright © 2010 by Stewart Scherer. All rights reserved.

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