Guide to the Human Genome
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Search of human proteins with 47716519

BLASTP 2.2.11 [Jun-05-2005]


Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer, 
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), 
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs",  Nucleic Acids Res. 25:3389-3402.

Query= gi|47716519 claudin 20 [Homo sapiens]
         (219 letters)

Database: hs.faa 
           37,866 sequences; 18,247,518 total letters

Searching..................................................done

                                                                 Score    E
Sequences producing significant alignments:                      (bits) Value

gi|47716519 claudin 20 [Homo sapiens]                                 442   e-124
gi|225703142 claudin 14 [Homo sapiens]                                172   2e-43
gi|21536294 claudin 14 [Homo sapiens]                                 172   2e-43
gi|225703138 claudin 14 [Homo sapiens]                                172   2e-43
gi|6912314 claudin 14 [Homo sapiens]                                  172   2e-43
gi|225703140 claudin 14 [Homo sapiens]                                172   2e-43
gi|153792186 claudin 7 [Homo sapiens]                                 162   3e-40
gi|9966781 claudin 2 [Homo sapiens]                                   154   6e-38
gi|10863887 claudin 1 [Homo sapiens]                                  147   9e-36
gi|183979973 claudin 19 isoform a [Homo sapiens]                      146   2e-35
gi|183979975 claudin 19 isoform b [Homo sapiens]                      146   2e-35
gi|4502877 claudin 4 [Homo sapiens]                                   137   7e-33
gi|4502875 claudin 3 [Homo sapiens]                                   135   3e-32
gi|11141861 claudin 9 [Homo sapiens]                                  134   5e-32
gi|195947374 claudin 5 [Homo sapiens]                                 133   1e-31
gi|195947372 claudin 5 [Homo sapiens]                                 133   1e-31
gi|153792768 claudin 6 [Homo sapiens]                                 132   2e-31
gi|40788011 claudin 8 [Homo sapiens]                                  123   1e-28
gi|6912316 claudin 17 [Homo sapiens]                                  113   1e-25
gi|5921465 claudin 10 isoform b [Homo sapiens]                        111   5e-25
gi|33598916 claudin 10 isoform a [Homo sapiens]                       107   6e-24
gi|50345279 claudin 18 isoform 2 [Homo sapiens]                       106   1e-23
gi|7705961 claudin 18 isoform 1 [Homo sapiens]                        105   2e-23
gi|7656981 claudin 15 [Homo sapiens]                                  105   2e-23
gi|231569235 claudin 10 isoform a_i1 [Homo sapiens]                    94   1e-19
gi|169166402 PREDICTED: claudin-24-like [Homo sapiens]                 83   2e-16
gi|169167239 PREDICTED: claudin-24-like [Homo sapiens]                 82   5e-16
gi|169166931 PREDICTED: claudin-24-like [Homo sapiens]                 82   5e-16
gi|162417973 claudin 22 [Homo sapiens]                                 80   2e-15
gi|10938016 claudin 11 [Homo sapiens]                                  70   2e-12

>gi|47716519 claudin 20 [Homo sapiens]
          Length = 219

 Score =  442 bits (1136), Expect = e-124
 Identities = 219/219 (100%), Positives = 219/219 (100%)

Query: 1   MASAGLQLLAFILALSGVSGVLTATLLPNWKVNVDVDSNIITAIVQLHGLWMDCTWYSTG 60
           MASAGLQLLAFILALSGVSGVLTATLLPNWKVNVDVDSNIITAIVQLHGLWMDCTWYSTG
Sbjct: 1   MASAGLQLLAFILALSGVSGVLTATLLPNWKVNVDVDSNIITAIVQLHGLWMDCTWYSTG 60

Query: 61  MFSCALKHSILSLPIHVQAARATMVLACVLSALGICTSTVGMKCTRLGGDRETKSHASFA 120
           MFSCALKHSILSLPIHVQAARATMVLACVLSALGICTSTVGMKCTRLGGDRETKSHASFA
Sbjct: 61  MFSCALKHSILSLPIHVQAARATMVLACVLSALGICTSTVGMKCTRLGGDRETKSHASFA 120

Query: 121 GGVCFMSAGISSLISTVWYTKEIIANFLDLTVPESNKHEPGGAIYIGFISAMLLFISGMI 180
           GGVCFMSAGISSLISTVWYTKEIIANFLDLTVPESNKHEPGGAIYIGFISAMLLFISGMI
Sbjct: 121 GGVCFMSAGISSLISTVWYTKEIIANFLDLTVPESNKHEPGGAIYIGFISAMLLFISGMI 180

Query: 181 FCTSCIKRNPEARLDPPTQQPISNTQLENNSTHNLKDYV 219
           FCTSCIKRNPEARLDPPTQQPISNTQLENNSTHNLKDYV
Sbjct: 181 FCTSCIKRNPEARLDPPTQQPISNTQLENNSTHNLKDYV 219


>gi|225703142 claudin 14 [Homo sapiens]
          Length = 239

 Score =  172 bits (437), Expect = 2e-43
 Identities = 83/211 (39%), Positives = 125/211 (59%), Gaps = 3/211 (1%)

Query: 1   MASAGLQLLAFILALSGVSGVLTATLLPNWKVNVDVDSNIITAIVQLHGLWMDCTWYSTG 60
           MAS  +QLL F+L+  G+ G L  T+LP+W+    V +NI+TA+  L GLWM+C W+STG
Sbjct: 1   MASTAVQLLGFLLSFLGMVGTLITTILPHWRRTAHVGTNILTAVSYLKGLWMECVWHSTG 60

Query: 61  MFSCALKHSILSLPIHVQAARATMVLACVLSALGICTSTVGMKCTRLGGDRETKSHASFA 120
           ++ C +  S+L+LP  +QAARA MV++C+LS +    + +GMKCTR       K+  +  
Sbjct: 61  IYQCQIYRSLLALPQDLQAARALMVISCLLSGIACACAVIGMKCTRCAKGTPAKTTFAIL 120

Query: 121 GGVCFMSAGISSLISTVWYTKEIIANFLDLTVPESNKHEPGGAIYIGFISAMLLFISGMI 180
           GG  F+ AG+  +++  W T +++ NF +  +P   K E G A+Y+GFIS+ L  I G +
Sbjct: 121 GGTLFILAGLLCMVAVSWTTNDVVQNFYNPLLPSGMKFEIGQALYLGFISSSLSLIGGTL 180

Query: 181 FCTSCIKRNPEARLDPPTQQPISNTQLENNS 211
            C SC     EA   P    P + T   N +
Sbjct: 181 LCLSC---QDEAPYRPYQAPPRATTTTANTA 208


>gi|21536294 claudin 14 [Homo sapiens]
          Length = 239

 Score =  172 bits (437), Expect = 2e-43
 Identities = 83/211 (39%), Positives = 125/211 (59%), Gaps = 3/211 (1%)

Query: 1   MASAGLQLLAFILALSGVSGVLTATLLPNWKVNVDVDSNIITAIVQLHGLWMDCTWYSTG 60
           MAS  +QLL F+L+  G+ G L  T+LP+W+    V +NI+TA+  L GLWM+C W+STG
Sbjct: 1   MASTAVQLLGFLLSFLGMVGTLITTILPHWRRTAHVGTNILTAVSYLKGLWMECVWHSTG 60

Query: 61  MFSCALKHSILSLPIHVQAARATMVLACVLSALGICTSTVGMKCTRLGGDRETKSHASFA 120
           ++ C +  S+L+LP  +QAARA MV++C+LS +    + +GMKCTR       K+  +  
Sbjct: 61  IYQCQIYRSLLALPQDLQAARALMVISCLLSGIACACAVIGMKCTRCAKGTPAKTTFAIL 120

Query: 121 GGVCFMSAGISSLISTVWYTKEIIANFLDLTVPESNKHEPGGAIYIGFISAMLLFISGMI 180
           GG  F+ AG+  +++  W T +++ NF +  +P   K E G A+Y+GFIS+ L  I G +
Sbjct: 121 GGTLFILAGLLCMVAVSWTTNDVVQNFYNPLLPSGMKFEIGQALYLGFISSSLSLIGGTL 180

Query: 181 FCTSCIKRNPEARLDPPTQQPISNTQLENNS 211
            C SC     EA   P    P + T   N +
Sbjct: 181 LCLSC---QDEAPYRPYQAPPRATTTTANTA 208


>gi|225703138 claudin 14 [Homo sapiens]
          Length = 239

 Score =  172 bits (437), Expect = 2e-43
 Identities = 83/211 (39%), Positives = 125/211 (59%), Gaps = 3/211 (1%)

Query: 1   MASAGLQLLAFILALSGVSGVLTATLLPNWKVNVDVDSNIITAIVQLHGLWMDCTWYSTG 60
           MAS  +QLL F+L+  G+ G L  T+LP+W+    V +NI+TA+  L GLWM+C W+STG
Sbjct: 1   MASTAVQLLGFLLSFLGMVGTLITTILPHWRRTAHVGTNILTAVSYLKGLWMECVWHSTG 60

Query: 61  MFSCALKHSILSLPIHVQAARATMVLACVLSALGICTSTVGMKCTRLGGDRETKSHASFA 120
           ++ C +  S+L+LP  +QAARA MV++C+LS +    + +GMKCTR       K+  +  
Sbjct: 61  IYQCQIYRSLLALPQDLQAARALMVISCLLSGIACACAVIGMKCTRCAKGTPAKTTFAIL 120

Query: 121 GGVCFMSAGISSLISTVWYTKEIIANFLDLTVPESNKHEPGGAIYIGFISAMLLFISGMI 180
           GG  F+ AG+  +++  W T +++ NF +  +P   K E G A+Y+GFIS+ L  I G +
Sbjct: 121 GGTLFILAGLLCMVAVSWTTNDVVQNFYNPLLPSGMKFEIGQALYLGFISSSLSLIGGTL 180

Query: 181 FCTSCIKRNPEARLDPPTQQPISNTQLENNS 211
            C SC     EA   P    P + T   N +
Sbjct: 181 LCLSC---QDEAPYRPYQAPPRATTTTANTA 208


>gi|6912314 claudin 14 [Homo sapiens]
          Length = 239

 Score =  172 bits (437), Expect = 2e-43
 Identities = 83/211 (39%), Positives = 125/211 (59%), Gaps = 3/211 (1%)

Query: 1   MASAGLQLLAFILALSGVSGVLTATLLPNWKVNVDVDSNIITAIVQLHGLWMDCTWYSTG 60
           MAS  +QLL F+L+  G+ G L  T+LP+W+    V +NI+TA+  L GLWM+C W+STG
Sbjct: 1   MASTAVQLLGFLLSFLGMVGTLITTILPHWRRTAHVGTNILTAVSYLKGLWMECVWHSTG 60

Query: 61  MFSCALKHSILSLPIHVQAARATMVLACVLSALGICTSTVGMKCTRLGGDRETKSHASFA 120
           ++ C +  S+L+LP  +QAARA MV++C+LS +    + +GMKCTR       K+  +  
Sbjct: 61  IYQCQIYRSLLALPQDLQAARALMVISCLLSGIACACAVIGMKCTRCAKGTPAKTTFAIL 120

Query: 121 GGVCFMSAGISSLISTVWYTKEIIANFLDLTVPESNKHEPGGAIYIGFISAMLLFISGMI 180
           GG  F+ AG+  +++  W T +++ NF +  +P   K E G A+Y+GFIS+ L  I G +
Sbjct: 121 GGTLFILAGLLCMVAVSWTTNDVVQNFYNPLLPSGMKFEIGQALYLGFISSSLSLIGGTL 180

Query: 181 FCTSCIKRNPEARLDPPTQQPISNTQLENNS 211
            C SC     EA   P    P + T   N +
Sbjct: 181 LCLSC---QDEAPYRPYQAPPRATTTTANTA 208


>gi|225703140 claudin 14 [Homo sapiens]
          Length = 239

 Score =  172 bits (437), Expect = 2e-43
 Identities = 83/211 (39%), Positives = 125/211 (59%), Gaps = 3/211 (1%)

Query: 1   MASAGLQLLAFILALSGVSGVLTATLLPNWKVNVDVDSNIITAIVQLHGLWMDCTWYSTG 60
           MAS  +QLL F+L+  G+ G L  T+LP+W+    V +NI+TA+  L GLWM+C W+STG
Sbjct: 1   MASTAVQLLGFLLSFLGMVGTLITTILPHWRRTAHVGTNILTAVSYLKGLWMECVWHSTG 60

Query: 61  MFSCALKHSILSLPIHVQAARATMVLACVLSALGICTSTVGMKCTRLGGDRETKSHASFA 120
           ++ C +  S+L+LP  +QAARA MV++C+LS +    + +GMKCTR       K+  +  
Sbjct: 61  IYQCQIYRSLLALPQDLQAARALMVISCLLSGIACACAVIGMKCTRCAKGTPAKTTFAIL 120

Query: 121 GGVCFMSAGISSLISTVWYTKEIIANFLDLTVPESNKHEPGGAIYIGFISAMLLFISGMI 180
           GG  F+ AG+  +++  W T +++ NF +  +P   K E G A+Y+GFIS+ L  I G +
Sbjct: 121 GGTLFILAGLLCMVAVSWTTNDVVQNFYNPLLPSGMKFEIGQALYLGFISSSLSLIGGTL 180

Query: 181 FCTSCIKRNPEARLDPPTQQPISNTQLENNS 211
            C SC     EA   P    P + T   N +
Sbjct: 181 LCLSC---QDEAPYRPYQAPPRATTTTANTA 208


>gi|153792186 claudin 7 [Homo sapiens]
          Length = 211

 Score =  162 bits (409), Expect = 3e-40
 Identities = 83/209 (39%), Positives = 126/209 (60%), Gaps = 1/209 (0%)

Query: 1   MASAGLQLLAFILALSGVSGVLTATLLPNWKVNVDVDSNIITAIVQLHGLWMDCTWYSTG 60
           MA++GLQLL F +AL G  G++  T +P W+++     NIITA     GLWMDC   STG
Sbjct: 1   MANSGLQLLGFSMALLGWVGLVACTAIPQWQMSSYAGDNIITAQAMYKGLWMDCVTQSTG 60

Query: 61  MFSCALKHSILSLPIHVQAARATMVLACVLSALGICTSTVGMKCTRLGG-DRETKSHASF 119
           M SC +  S+L+L   +QA RA MV++ VL  L +  +T+GMKCTR GG D+  K+  + 
Sbjct: 61  MMSCKMYDSVLALSAALQATRALMVVSLVLGFLAMFVATMGMKCTRCGGDDKVKKARIAM 120

Query: 120 AGGVCFMSAGISSLISTVWYTKEIIANFLDLTVPESNKHEPGGAIYIGFISAMLLFISGM 179
            GG+ F+ AG+++L++  WY  +I+ +F +  +P + K+E G AI+IG+  + L+ + G 
Sbjct: 121 GGGIIFIVAGLAALVACSWYGHQIVTDFYNPLIPTNIKYEFGPAIFIGWAGSALVILGGA 180

Query: 180 IFCTSCIKRNPEARLDPPTQQPISNTQLE 208
           +   SC     +A    P   P SN+  E
Sbjct: 181 LLSCSCPGNESKAGYRVPRSYPKSNSSKE 209


>gi|9966781 claudin 2 [Homo sapiens]
          Length = 230

 Score =  154 bits (389), Expect = 6e-38
 Identities = 82/204 (40%), Positives = 119/204 (58%), Gaps = 1/204 (0%)

Query: 1   MASAGLQLLAFILALSGVSGVLTATLLPNWKVNVDVDSNIITAIVQLHGLWMDCTWYSTG 60
           MAS GLQL+ +IL L G+ G L A LLP+WK +  V ++I+TA+    GLWM+C  +STG
Sbjct: 1   MASLGLQLVGYILGLLGLLGTLVAMLLPSWKTSSYVGASIVTAVGFSKGLWMECATHSTG 60

Query: 61  MFSCALKHSILSLPIHVQAARATMVLACVLSALGICTSTVGMKCTRLGGDRETKSHASFA 120
           +  C +  ++L LP  +QAA+A MV +  +S+L    S VGM+CT    +   K   + A
Sbjct: 61  ITQCDIYSTLLGLPADIQAAQAMMVTSSAISSLACIISVVGMRCTVFCQESRAKDRVAVA 120

Query: 121 GGVCFMSAGISSLISTVWYTKEIIANFLDLTVPESNKHEPGGAIYIGFISAMLLFISGMI 180
           GGV F+  G+   I   W    I+ +F    VP+S K E G A+Y+G IS++   I+G+I
Sbjct: 121 GGVFFILGGLLGFIPVAWNLHGILRDFYSPLVPDSMKFEIGEALYLGIISSLFSLIAGII 180

Query: 181 FCTSC-IKRNPEARLDPPTQQPIS 203
            C SC  +RN     D    QP++
Sbjct: 181 LCFSCSSQRNRSNYYDAYQAQPLA 204


>gi|10863887 claudin 1 [Homo sapiens]
          Length = 211

 Score =  147 bits (370), Expect = 9e-36
 Identities = 78/202 (38%), Positives = 110/202 (54%), Gaps = 5/202 (2%)

Query: 1   MASAGLQLLAFILALSGVSGVLTATLLPNWKVNVDVDSNIITAIVQLHGLWMDCTWYSTG 60
           MA+AGLQLL FILA  G  G + +T LP W++      NI+TA     GLWM C   STG
Sbjct: 1   MANAGLQLLGFILAFLGWIGAIVSTALPQWRIYSYAGDNIVTAQAMYEGLWMSCVSQSTG 60

Query: 61  MFSCALKHSILSLPIHVQAARATMVLACVLSALGICTSTVGMKCTR-LGGDRETKSHASF 119
              C +  S+L+L   +QA RA MV+  +L  + I  +TVGMKC + L  D   K   + 
Sbjct: 61  QIQCKVFDSLLNLSSTLQATRALMVVGILLGVIAIFVATVGMKCMKCLEDDEVQKMRMAV 120

Query: 120 AGGVCFMSAGISSLISTVWYTKEIIANFLDLTVPESNKHEPGGAIYIGFISAMLLFISGM 179
            GG  F+ AG++ L++T WY   I+  F D   P + ++E G A++ G+ +A L  + G 
Sbjct: 121 IGGAIFLLAGLAILVATAWYGNRIVQEFYDPMTPVNARYEFGQALFTGWAAASLCLLGGA 180

Query: 180 IFCTSCIKRNPEARLDPPTQQP 201
           + C SC    P      PT +P
Sbjct: 181 LLCCSC----PRKTTSYPTPRP 198


>gi|183979973 claudin 19 isoform a [Homo sapiens]
          Length = 224

 Score =  146 bits (368), Expect = 2e-35
 Identities = 78/202 (38%), Positives = 113/202 (55%), Gaps = 5/202 (2%)

Query: 1   MASAGLQLLAFILALSGVSGVLTATLLPNWKVNVDVDSNIITAIVQLHGLWMDCTWYSTG 60
           MA++GLQLL + LAL G  G++ +T LP WK +      IITA+    GLWM C   STG
Sbjct: 1   MANSGLQLLGYFLALGGWVGIIASTALPQWKQSSYAGDAIITAVGLYEGLWMSCASQSTG 60

Query: 61  MFSCALKHSILSLPIHVQAARATMVLACVLSALGICTSTVGMKCTRLGGDRE-TKSHASF 119
              C L  S+L+L  H+Q+ARA MV+A +L  + +  S VGMKCTR+G      K   + 
Sbjct: 61  QVQCKLYDSLLALDGHIQSARALMVVAVLLGFVAMVLSVVGMKCTRVGDSNPIAKGRVAI 120

Query: 120 AGGVCFMSAGISSLISTVWYTKEIIANFLDLTVPESNKHEPGGAIYIGFISAMLLFISGM 179
           AGG  F+ AG+ +L +  WY   +   F + + P + ++E G A+++G+ SA L  + G 
Sbjct: 121 AGGALFILAGLCTLTAVSWYATLVTQEFFNPSTPVNARYEFGPALFVGWASAGLAVLGGS 180

Query: 180 IFCTSCIKRNPEARLDPPTQQP 201
             C +C    PE      + QP
Sbjct: 181 FLCCTC----PEPERPNSSPQP 198


>gi|183979975 claudin 19 isoform b [Homo sapiens]
          Length = 211

 Score =  146 bits (368), Expect = 2e-35
 Identities = 78/202 (38%), Positives = 113/202 (55%), Gaps = 5/202 (2%)

Query: 1   MASAGLQLLAFILALSGVSGVLTATLLPNWKVNVDVDSNIITAIVQLHGLWMDCTWYSTG 60
           MA++GLQLL + LAL G  G++ +T LP WK +      IITA+    GLWM C   STG
Sbjct: 1   MANSGLQLLGYFLALGGWVGIIASTALPQWKQSSYAGDAIITAVGLYEGLWMSCASQSTG 60

Query: 61  MFSCALKHSILSLPIHVQAARATMVLACVLSALGICTSTVGMKCTRLGGDRE-TKSHASF 119
              C L  S+L+L  H+Q+ARA MV+A +L  + +  S VGMKCTR+G      K   + 
Sbjct: 61  QVQCKLYDSLLALDGHIQSARALMVVAVLLGFVAMVLSVVGMKCTRVGDSNPIAKGRVAI 120

Query: 120 AGGVCFMSAGISSLISTVWYTKEIIANFLDLTVPESNKHEPGGAIYIGFISAMLLFISGM 179
           AGG  F+ AG+ +L +  WY   +   F + + P + ++E G A+++G+ SA L  + G 
Sbjct: 121 AGGALFILAGLCTLTAVSWYATLVTQEFFNPSTPVNARYEFGPALFVGWASAGLAVLGGS 180

Query: 180 IFCTSCIKRNPEARLDPPTQQP 201
             C +C    PE      + QP
Sbjct: 181 FLCCTC----PEPERPNSSPQP 198


>gi|4502877 claudin 4 [Homo sapiens]
          Length = 209

 Score =  137 bits (345), Expect = 7e-33
 Identities = 68/188 (36%), Positives = 105/188 (55%)

Query: 1   MASAGLQLLAFILALSGVSGVLTATLLPNWKVNVDVDSNIITAIVQLHGLWMDCTWYSTG 60
           MAS GLQ++   LA+ G   V+    LP W+V   + SNI+T+     GLWM+C   STG
Sbjct: 1   MASMGLQVMGIALAVLGWLAVMLCCALPMWRVTAFIGSNIVTSQTIWEGLWMNCVVQSTG 60

Query: 61  MFSCALKHSILSLPIHVQAARATMVLACVLSALGICTSTVGMKCTRLGGDRETKSHASFA 120
              C +  S+L+LP  +QAARA ++++ +++ALG+  S VG KCT    D   K+     
Sbjct: 61  QMQCKVYDSLLALPQDLQAARALVIISIIVAALGVLLSVVGGKCTNCLEDESAKAKTMIV 120

Query: 121 GGVCFMSAGISSLISTVWYTKEIIANFLDLTVPESNKHEPGGAIYIGFISAMLLFISGMI 180
            GV F+ AG+  ++   W    II +F +  V    K E G ++Y+G+ ++ LL + G +
Sbjct: 121 AGVVFLLAGLMVIVPVSWTAHNIIQDFYNPLVASGQKREMGASLYVGWAASGLLLLGGGL 180

Query: 181 FCTSCIKR 188
            C +C  R
Sbjct: 181 LCCNCPPR 188


>gi|4502875 claudin 3 [Homo sapiens]
          Length = 220

 Score =  135 bits (340), Expect = 3e-32
 Identities = 69/186 (37%), Positives = 104/186 (55%)

Query: 3   SAGLQLLAFILALSGVSGVLTATLLPNWKVNVDVDSNIITAIVQLHGLWMDCTWYSTGMF 62
           S GL++    LA+ G  G +    LP W+V+  + SNIIT+     GLWM+C   STG  
Sbjct: 2   SMGLEITGTALAVLGWLGTIVCCALPMWRVSAFIGSNIITSQNIWEGLWMNCVVQSTGQM 61

Query: 63  SCALKHSILSLPIHVQAARATMVLACVLSALGICTSTVGMKCTRLGGDRETKSHASFAGG 122
            C +  S+L+LP  +QAARA +V+A +L+A G+  + VG +CT    D   K+  +   G
Sbjct: 62  QCKVYDSLLALPQDLQAARALIVVAILLAAFGLLVALVGAQCTNCVQDDTAKAKITIVAG 121

Query: 123 VCFMSAGISSLISTVWYTKEIIANFLDLTVPESNKHEPGGAIYIGFISAMLLFISGMIFC 182
           V F+ A + +L+   W    II +F +  VPE+ K E G  +Y+G+ +A L  + G + C
Sbjct: 122 VLFLLAALLTLVPVSWSANTIIRDFYNPVVPEAQKREMGAGLYVGWAAAALQLLGGALLC 181

Query: 183 TSCIKR 188
            SC  R
Sbjct: 182 CSCPPR 187


>gi|11141861 claudin 9 [Homo sapiens]
          Length = 217

 Score =  134 bits (338), Expect = 5e-32
 Identities = 72/185 (38%), Positives = 102/185 (55%)

Query: 1   MASAGLQLLAFILALSGVSGVLTATLLPNWKVNVDVDSNIITAIVQLHGLWMDCTWYSTG 60
           MAS GL+LL   LA+ G  G L +  LP WKV   + ++I+ A V   GLWM C   STG
Sbjct: 1   MASTGLELLGMTLAVLGWLGTLVSCALPLWKVTAFIGNSIVVAQVVWEGLWMSCVVQSTG 60

Query: 61  MFSCALKHSILSLPIHVQAARATMVLACVLSALGICTSTVGMKCTRLGGDRETKSHASFA 120
              C +  S+L+LP  +QAARA  V+A +L+ LG+  +  G +CT    D   K+     
Sbjct: 61  QMQCKVYDSLLALPQDLQAARALCVIALLLALLGLLVAITGAQCTTCVEDEGAKARIVLT 120

Query: 121 GGVCFMSAGISSLISTVWYTKEIIANFLDLTVPESNKHEPGGAIYIGFISAMLLFISGMI 180
            GV  + AGI  LI   W    II +F +  V E+ K E G ++Y+G+ +A LL + G +
Sbjct: 121 AGVILLLAGILVLIPVCWTAHAIIQDFYNPLVAEALKRELGASLYLGWAAAALLMLGGGL 180

Query: 181 FCTSC 185
            C +C
Sbjct: 181 LCCTC 185


>gi|195947374 claudin 5 [Homo sapiens]
          Length = 303

 Score =  133 bits (335), Expect = 1e-31
 Identities = 66/182 (36%), Positives = 100/182 (54%)

Query: 1   MASAGLQLLAFILALSGVSGVLTATLLPNWKVNVDVDSNIITAIVQLHGLWMDCTWYSTG 60
           M SA L++L  +L L G  G++ A  LP W+V   +D NI+TA     GLWM C   STG
Sbjct: 86  MGSAALEILGLVLCLVGWGGLILACGLPMWQVTAFLDHNIVTAQTTWKGLWMSCVVQSTG 145

Query: 61  MFSCALKHSILSLPIHVQAARATMVLACVLSALGICTSTVGMKCTRLGGDRETKSHASFA 120
              C +  S+L+L   VQAARA  V A +L+ + +  +  G +CT        K+  +  
Sbjct: 146 HMQCKVYDSVLALSTEVQAARALTVSAVLLAFVALFVTLAGAQCTTCVAPGPAKARVALT 205

Query: 121 GGVCFMSAGISSLISTVWYTKEIIANFLDLTVPESNKHEPGGAIYIGFISAMLLFISGMI 180
           GGV ++  G+ +L+   W+   ++  F D +VP S K+E G A+YIG+ +  LL + G +
Sbjct: 206 GGVLYLFCGLLALVPLCWFANIVVREFYDPSVPVSQKYELGAALYIGWAATALLMVGGCL 265

Query: 181 FC 182
            C
Sbjct: 266 LC 267


>gi|195947372 claudin 5 [Homo sapiens]
          Length = 303

 Score =  133 bits (335), Expect = 1e-31
 Identities = 66/182 (36%), Positives = 100/182 (54%)

Query: 1   MASAGLQLLAFILALSGVSGVLTATLLPNWKVNVDVDSNIITAIVQLHGLWMDCTWYSTG 60
           M SA L++L  +L L G  G++ A  LP W+V   +D NI+TA     GLWM C   STG
Sbjct: 86  MGSAALEILGLVLCLVGWGGLILACGLPMWQVTAFLDHNIVTAQTTWKGLWMSCVVQSTG 145

Query: 61  MFSCALKHSILSLPIHVQAARATMVLACVLSALGICTSTVGMKCTRLGGDRETKSHASFA 120
              C +  S+L+L   VQAARA  V A +L+ + +  +  G +CT        K+  +  
Sbjct: 146 HMQCKVYDSVLALSTEVQAARALTVSAVLLAFVALFVTLAGAQCTTCVAPGPAKARVALT 205

Query: 121 GGVCFMSAGISSLISTVWYTKEIIANFLDLTVPESNKHEPGGAIYIGFISAMLLFISGMI 180
           GGV ++  G+ +L+   W+   ++  F D +VP S K+E G A+YIG+ +  LL + G +
Sbjct: 206 GGVLYLFCGLLALVPLCWFANIVVREFYDPSVPVSQKYELGAALYIGWAATALLMVGGCL 265

Query: 181 FC 182
            C
Sbjct: 266 LC 267


>gi|153792768 claudin 6 [Homo sapiens]
          Length = 220

 Score =  132 bits (333), Expect = 2e-31
 Identities = 66/185 (35%), Positives = 105/185 (56%)

Query: 1   MASAGLQLLAFILALSGVSGVLTATLLPNWKVNVDVDSNIITAIVQLHGLWMDCTWYSTG 60
           MASAG+Q+L  +L L G    L +  LP WKV   + ++I+ A V   GLWM C   STG
Sbjct: 1   MASAGMQILGVVLTLLGWVNGLVSCALPMWKVTAFIGNSIVVAQVVWEGLWMSCVVQSTG 60

Query: 61  MFSCALKHSILSLPIHVQAARATMVLACVLSALGICTSTVGMKCTRLGGDRETKSHASFA 120
              C +  S+L+LP  +QAARA  V+A +++  G+     G KCT    ++++K+     
Sbjct: 61  QMQCKVYDSLLALPQDLQAARALCVIALLVALFGLLVYLAGAKCTTCVEEKDSKARLVLT 120

Query: 121 GGVCFMSAGISSLISTVWYTKEIIANFLDLTVPESNKHEPGGAIYIGFISAMLLFISGMI 180
            G+ F+ +G+ +LI   W    II +F +  V E+ K E G ++Y+G+ ++ LL + G +
Sbjct: 121 SGIVFVISGVLTLIPVCWTAHAIIRDFYNPLVAEAQKRELGASLYLGWAASGLLLLGGGL 180

Query: 181 FCTSC 185
            C +C
Sbjct: 181 LCCTC 185


>gi|40788011 claudin 8 [Homo sapiens]
          Length = 225

 Score =  123 bits (308), Expect = 1e-28
 Identities = 71/225 (31%), Positives = 116/225 (51%), Gaps = 6/225 (2%)

Query: 1   MASAGLQLLAFILALSGVSGVLTATLLPNWKVNVDVDSNIITAIVQLHGLWMDCTWYSTG 60
           MA+  L++    L   G+ G +  T++P W+V+  +++NI+       GLWM+C   +  
Sbjct: 1   MATHALEIAGLFLGGVGMVGTVAVTVMPQWRVSAFIENNIVVFENFWEGLWMNCVRQANI 60

Query: 61  MFSCALKHSILSLPIHVQAARATMVLACVLSALGICTSTVGMKCTRLGGDRE-TKSHASF 119
              C +  S+L+L   +QAAR  M  A V+S L    + +GMKCTR  GD E  K+H   
Sbjct: 61  RMQCKIYDSLLALSPDLQAARGLMCAASVMSFLAFMMAILGMKCTRCTGDNEKVKAHILL 120

Query: 120 AGGVCFMSAGISSLISTVWYTKEIIANFLDLTVPESNKHEPGGAIYIGFISAMLLFISGM 179
             G+ F+  G+  LI   W    II +F +  V  + K E G A+Y+G+ +A++L + G 
Sbjct: 121 TAGIIFIITGMVVLIPVSWVANAIIRDFYNSIVNVAQKRELGEALYLGWTTALVLIVGGA 180

Query: 180 IFCT--SCIKRNPEARLDPP---TQQPISNTQLENNSTHNLKDYV 219
           +FC    C +++   R   P   T Q   +T  ++ S ++   YV
Sbjct: 181 LFCCVFCCNEKSSSYRYSIPSHRTTQKSYHTGKKSPSVYSRSQYV 225


>gi|6912316 claudin 17 [Homo sapiens]
          Length = 224

 Score =  113 bits (283), Expect = 1e-25
 Identities = 72/216 (33%), Positives = 103/216 (47%), Gaps = 6/216 (2%)

Query: 1   MASAGLQLLAFILALSGVSGVLTATLLPNWKVNVDVDSNIITAIVQLHGLWMDCTWYSTG 60
           MA   LQ+   +L   G+ G L  TLLP W+V+  V SNII       GLWM+C   +  
Sbjct: 1   MAFYPLQIAGLVLGFLGMVGTLATTLLPQWRVSAFVGSNIIVFERLWEGLWMNCIRQARV 60

Query: 61  MFSCALKHSILSLPIHVQAARATMVLACVLSALGICTSTVGMK---CTRLGGDRETKSHA 117
              C    S+L+LP  ++ ARA M +A  LS + +     GMK   CT  G +   K++ 
Sbjct: 61  RLQCKFYSSLLALPPALETARALMCVAVALSLIALLIGICGMKQVQCT--GSNERAKAYL 118

Query: 118 SFAGGVCFMSAGISSLISTVWYTKEIIANFLDLTVPESNKHEPGGAIYIGFISAMLLFIS 177
               GV F+  GI  LI   W    II +F +  +    K E G A+++G+ SA +LFI 
Sbjct: 119 LGTSGVLFILTGIFVLIPVSWTANIIIRDFYNPAIHIGQKRELGAALFLGWASAAVLFIG 178

Query: 178 GMIFC-TSCIKRNPEARLDPPTQQPISNTQLENNST 212
           G + C   C  R  +    P     + +T    N+T
Sbjct: 179 GGLLCGFCCCNRKKQGYRYPVPGYRVPHTDKRRNTT 214


>gi|5921465 claudin 10 isoform b [Homo sapiens]
          Length = 228

 Score =  111 bits (277), Expect = 5e-25
 Identities = 67/195 (34%), Positives = 103/195 (52%), Gaps = 6/195 (3%)

Query: 1   MASAGLQLLAFILALSGVSGVLTATLLPN--WKVNVDVDSNIITAIVQLHGLWMDCTWYS 58
           MAS   +++AF++++SG   VL ++ LP   WKV+  +D  +IT       LW  C   S
Sbjct: 1   MASTASEIIAFMVSISG--WVLVSSTLPTDYWKVST-IDGTVITTATYWANLWKACVTDS 57

Query: 59  TGMFSCALKHSILSLPIHVQAARATMVLACVLSALGICTSTVGMKCTRLGGDRETKSHAS 118
           TG+ +C    S+L+L  ++QA R  M+ A  L   G   +  GMKCT++GG  + K+  +
Sbjct: 58  TGVSNCKDFPSMLALDGYIQACRGLMIAAVSLGFFGSIFALFGMKCTKVGGSDKAKAKIA 117

Query: 119 FAGGVCFMSAGISSLISTVWYTKEIIANFLDLTVPESNKHEPGGAIYIGFISAMLLFISG 178
              G+ F+ +G+ S+     Y  +I   F D    E  K+E G A++IG+  A L  I G
Sbjct: 118 CLAGIVFILSGLCSMTGCSLYANKITTEFFDPLFVE-QKYELGAALFIGWAGASLCIIGG 176

Query: 179 MIFCTSCIKRNPEAR 193
           +IFC S    N   R
Sbjct: 177 VIFCFSISDNNKTPR 191


>gi|33598916 claudin 10 isoform a [Homo sapiens]
          Length = 226

 Score =  107 bits (268), Expect = 6e-24
 Identities = 61/187 (32%), Positives = 92/187 (49%), Gaps = 2/187 (1%)

Query: 7   QLLAFILALSGVSGVLTATLLPNWKVNVDVDSNIITAIVQLHGLWMDCTWYSTGMFSCAL 66
           Q+ A +  + G   ++ AT    WKV     S++ITA     GLWM+C   + G F C  
Sbjct: 5   QIWALVSGVGGFGALVAATTSNEWKVTTRA-SSVITATWVYQGLWMNCAGNALGSFHCRP 63

Query: 67  KHSILSLPIHVQAARATMVLACVLSALGICTSTVGMKCTRLGGDRETKSHASFAGGVCFM 126
             +I  +  ++QA R  M+ A  L   G   +  GMKCT++GG  + K+  +   G+ F+
Sbjct: 64  HFTIFKVAGYIQACRGLMIAAVSLGFFGSIFALFGMKCTKVGGSDKAKAKIACLAGIVFI 123

Query: 127 SAGISSLISTVWYTKEIIANFLDLTVPESNKHEPGGAIYIGFISAMLLFISGMIFCTSCI 186
            +G+ S+     Y  +I   F D    E  K+E G A++IG+  A L  I G+IFC S  
Sbjct: 124 LSGLCSMTGCSLYANKITTEFFDPLFVE-QKYELGAALFIGWAGASLCIIGGVIFCFSIS 182

Query: 187 KRNPEAR 193
             N   R
Sbjct: 183 DNNKTPR 189


>gi|50345279 claudin 18 isoform 2 [Homo sapiens]
          Length = 261

 Score =  106 bits (265), Expect = 1e-23
 Identities = 56/203 (27%), Positives = 102/203 (50%), Gaps = 13/203 (6%)

Query: 1   MASAGLQLLAFILALSGVSGVLTATLLPNWKVNVDVDSNIITAIVQLHGLWMDCTWYSTG 60
           MA    Q L F+++L G++G++ AT +  W    D+ +N +TA+    GLW  C   S+G
Sbjct: 1   MAVTACQGLGFVVSLIGIAGIIAATCMDQWSTQ-DLYNNPVTAVFNYQGLWRSCVRESSG 59

Query: 61  MFSCALKHSILSLPIHVQAARATMVLACVLSALGICTSTVGMKCTRLGG-DRETKSHASF 119
              C    ++L LP  +QA RA M++  VL A+G+  S   +KC R+G  +   K++ + 
Sbjct: 60  FTECRGYFTLLGLPAMLQAVRALMIVGIVLGAIGLLVSIFALKCIRIGSMEDSAKANMTL 119

Query: 120 AGGVCFMSAGISSLISTVWYTKEIIANFLDLTV-----------PESNKHEPGGAIYIGF 168
             G+ F+ +G+ ++     +   ++ NF   T                ++  G A+++G+
Sbjct: 120 TSGIMFIVSGLCAIAGVSVFANMLVTNFWMSTANMYTGMGGMVQTVQTRYTFGAALFVGW 179

Query: 169 ISAMLLFISGMIFCTSCIKRNPE 191
           ++  L  I G++ C +C    PE
Sbjct: 180 VAGGLTLIGGVMMCIACRGLAPE 202


>gi|7705961 claudin 18 isoform 1 [Homo sapiens]
          Length = 261

 Score =  105 bits (263), Expect = 2e-23
 Identities = 56/203 (27%), Positives = 104/203 (51%), Gaps = 13/203 (6%)

Query: 1   MASAGLQLLAFILALSGVSGVLTATLLPNWKVNVDVDSNIITAIVQLHGLWMDCTWYSTG 60
           M++   Q++AF+L++ G++G + AT +  W    D+  N +T++ Q  GLW  C   S+G
Sbjct: 1   MSTTTCQVVAFLLSILGLAGCIAATGMDMWSTQ-DLYDNPVTSVFQYEGLWRSCVRQSSG 59

Query: 61  MFSCALKHSILSLPIHVQAARATMVLACVLSALGICTSTVGMKCTRLGG-DRETKSHASF 119
              C    +IL LP  +QA RA M++  VL A+G+  S   +KC R+G  +   K++ + 
Sbjct: 60  FTECRPYFTILGLPAMLQAVRALMIVGIVLGAIGLLVSIFALKCIRIGSMEDSAKANMTL 119

Query: 120 AGGVCFMSAGISSLISTVWYTKEIIANFLDLTV-----------PESNKHEPGGAIYIGF 168
             G+ F+ +G+ ++     +   ++ NF   T                ++  G A+++G+
Sbjct: 120 TSGIMFIVSGLCAIAGVSVFANMLVTNFWMSTANMYTGMGGMVQTVQTRYTFGAALFVGW 179

Query: 169 ISAMLLFISGMIFCTSCIKRNPE 191
           ++  L  I G++ C +C    PE
Sbjct: 180 VAGGLTLIGGVMMCIACRGLAPE 202


>gi|7656981 claudin 15 [Homo sapiens]
          Length = 228

 Score =  105 bits (263), Expect = 2e-23
 Identities = 62/207 (29%), Positives = 106/207 (51%), Gaps = 10/207 (4%)

Query: 3   SAGLQLLAFILALSGVSGVLTATLLPN--WKVNVDVDSNIITAIVQLHGLWMDCTWYSTG 60
           S  ++   F +A  G+  ++    LPN  W+V+  V  N+IT       LW  C   S G
Sbjct: 2   SMAVETFGFFMATVGL--LMLGVTLPNSYWRVST-VHGNVITTNTIFENLWFSCATDSLG 58

Query: 61  MFSCALKHSILSLPIHVQAARATMVLACVLSALGICTSTVGMKCTRLGG-DRETKSHASF 119
           +++C    S+L+L  ++QA RA M+ A +L  LG+     G++CT +GG +   K+  + 
Sbjct: 59  VYNCWEFPSMLALSGYIQACRALMITAILLGFLGLLLGIAGLRCTNIGGLELSRKAKLAA 118

Query: 120 AGGVCFMSAGISSLISTVWYTKEIIANFLDLTVPESNKHEPGGAIYIGFISAMLLFISGM 179
             G   + AGI  +++  WY   I  +F D   P   K+E G A+Y+G+ ++++  + G+
Sbjct: 119 TAGALHILAGICGMVAISWYAFNITRDFFDPLYP-GTKYELGPALYLGWSASLISILGGL 177

Query: 180 IFCTSCI---KRNPEARLDPPTQQPIS 203
             C++C      +P A    P Q P+S
Sbjct: 178 CLCSACCCGSDEDPAASARRPYQAPVS 204


>gi|231569235 claudin 10 isoform a_i1 [Homo sapiens]
          Length = 207

 Score = 93.6 bits (231), Expect = 1e-19
 Identities = 58/187 (31%), Positives = 85/187 (45%), Gaps = 21/187 (11%)

Query: 7   QLLAFILALSGVSGVLTATLLPNWKVNVDVDSNIITAIVQLHGLWMDCTWYSTGMFSCAL 66
           Q+ A +  + G   ++ AT    WKV     S++ITA     GLWM+C  Y         
Sbjct: 5   QIWALVSGVGGFGALVAATTSNEWKVTTRA-SSVITATWVYQGLWMNCAGY--------- 54

Query: 67  KHSILSLPIHVQAARATMVLACVLSALGICTSTVGMKCTRLGGDRETKSHASFAGGVCFM 126
                     +QA R  M+ A  L   G   +  GMKCT++GG  + K+  +   G+ F+
Sbjct: 55  ----------IQACRGLMIAAVSLGFFGSIFALFGMKCTKVGGSDKAKAKIACLAGIVFI 104

Query: 127 SAGISSLISTVWYTKEIIANFLDLTVPESNKHEPGGAIYIGFISAMLLFISGMIFCTSCI 186
            +G+ S+     Y  +I   F D    E  K+E G A++IG+  A L  I G+IFC S  
Sbjct: 105 LSGLCSMTGCSLYANKITTEFFDPLFVE-QKYELGAALFIGWAGASLCIIGGVIFCFSIS 163

Query: 187 KRNPEAR 193
             N   R
Sbjct: 164 DNNKTPR 170


>gi|169166402 PREDICTED: claudin-24-like [Homo sapiens]
          Length = 220

 Score = 82.8 bits (203), Expect = 2e-16
 Identities = 54/190 (28%), Positives = 93/190 (48%), Gaps = 6/190 (3%)

Query: 6   LQLLAFILALSGVSGVLTATLLPNWKVNVDVDSNIITAIVQLHGLWMDCTWYSTGMFSCA 65
           +Q +  +L+L G    +  T LP+WK N+++D N +       GLW  C         C 
Sbjct: 9   MQSVGLLLSLLGWILSIITTYLPHWK-NLNLDLNEMENWTM--GLWQTCVIQEEVGMQCK 65

Query: 66  LKHSILSLPIHVQAARATMVLACVLSALGICTSTVGMKCTRLG-GDRETKSHASFAGGVC 124
              S L+LP  ++ +R  M L+  L  LG+  S  G+ C R+G   R+ K      GG+ 
Sbjct: 66  DFDSFLALPAELRVSRILMFLSNGLGFLGLLVSGFGLDCLRIGESQRDLKRRLLILGGIL 125

Query: 125 FMSAGISSLISTVWYTKEIIANFLDLTVPE-SNKHEPGGAIYIGFISAMLLFISG-MIFC 182
             ++GI++L+   W   + +  F D  VP+   + E G A+++G+ + + L + G ++ C
Sbjct: 126 SWASGITALVPVSWVAHKTVQEFWDENVPDFVPRWEFGEALFLGWFAGLSLLLGGCLLNC 185

Query: 183 TSCIKRNPEA 192
            +C    P A
Sbjct: 186 AACSSHAPLA 195


>gi|169167239 PREDICTED: claudin-24-like [Homo sapiens]
          Length = 220

 Score = 81.6 bits (200), Expect = 5e-16
 Identities = 59/195 (30%), Positives = 97/195 (49%), Gaps = 11/195 (5%)

Query: 1   MASAGLQLLAFILALSGVSGVLTATLLPNWKVNVDVDSNIITAIVQLHGLWMDCTWYSTG 60
           M S GL LL+F   L  +  ++T T LP+WK N+++D N +       GLW  C      
Sbjct: 9   MQSVGL-LLSF---LGWILSIIT-TYLPHWK-NLNLDLNEMENWTM--GLWQTCVIQEEV 60

Query: 61  MFSCALKHSILSLPIHVQAARATMVLACVLSALGICTSTVGMKCTRLG-GDRETKSHASF 119
              C    S L+LP  ++ +R  M L+  L  LG+  S  G+ C R+G   R+ K     
Sbjct: 61  GMQCKDFDSFLALPAELRVSRILMFLSNGLGFLGLLVSGFGLDCLRIGESQRDLKRRLLI 120

Query: 120 AGGVCFMSAGISSLISTVWYTKEIIANFLDLTVPE-SNKHEPGGAIYIGFISAMLLFISG 178
            GG+   ++GI++L+   W   + +  F D  VP+   + E G A+++G+ + + L + G
Sbjct: 121 LGGILSWASGITALVPVSWVAHKTVQEFWDENVPDFVPRWEFGEALFLGWFAGLSLLLGG 180

Query: 179 -MIFCTSCIKRNPEA 192
            ++ C +C    P A
Sbjct: 181 CLLNCAACSSHAPLA 195


>gi|169166931 PREDICTED: claudin-24-like [Homo sapiens]
          Length = 220

 Score = 81.6 bits (200), Expect = 5e-16
 Identities = 59/195 (30%), Positives = 97/195 (49%), Gaps = 11/195 (5%)

Query: 1   MASAGLQLLAFILALSGVSGVLTATLLPNWKVNVDVDSNIITAIVQLHGLWMDCTWYSTG 60
           M S GL LL+F   L  +  ++T T LP+WK N+++D N +       GLW  C      
Sbjct: 9   MQSVGL-LLSF---LGWILSIIT-TYLPHWK-NLNLDLNEMENWTM--GLWQTCVIQEEV 60

Query: 61  MFSCALKHSILSLPIHVQAARATMVLACVLSALGICTSTVGMKCTRLG-GDRETKSHASF 119
              C    S L+LP  ++ +R  M L+  L  LG+  S  G+ C R+G   R+ K     
Sbjct: 61  GMQCKDFDSFLALPAELRVSRILMFLSNGLGFLGLLVSGFGLDCLRIGESQRDLKRRLLI 120

Query: 120 AGGVCFMSAGISSLISTVWYTKEIIANFLDLTVPE-SNKHEPGGAIYIGFISAMLLFISG 178
            GG+   ++GI++L+   W   + +  F D  VP+   + E G A+++G+ + + L + G
Sbjct: 121 LGGILSWASGITALVPVSWVAHKTVQEFWDENVPDFVPRWEFGEALFLGWFAGLSLLLGG 180

Query: 179 -MIFCTSCIKRNPEA 192
            ++ C +C    P A
Sbjct: 181 CLLNCAACSSHAPLA 195


>gi|162417973 claudin 22 [Homo sapiens]
          Length = 220

 Score = 79.7 bits (195), Expect = 2e-15
 Identities = 53/195 (27%), Positives = 92/195 (47%), Gaps = 13/195 (6%)

Query: 1   MASAGLQLLAFILALSGVSGVLTATLLPNWKVNVDVDSNIITAIVQLHGLWMDCTWYSTG 60
           +A   L LL ++L+            LP+WK N+++D N +       GLW  C      
Sbjct: 11  LAGVSLSLLGWVLSC-------LTNYLPHWK-NLNLDLNEMENWTM--GLWQTCVIQEEV 60

Query: 61  MFSCALKHSILSLPIHVQAARATMVLACVLSALGICTSTVGMKCTRLG-GDRETKSHASF 119
              C    S L+LP  ++ +R  M L+  L  LG+  S  G+ C R+G   R+ K     
Sbjct: 61  GMQCKDFDSFLALPAELRVSRILMFLSNGLGFLGLLVSGFGLDCLRIGESQRDLKRRLLI 120

Query: 120 AGGVCFMSAGISSLISTVWYTKEIIANFLDLTVPE-SNKHEPGGAIYIGFISAMLLFISG 178
            GG+   ++G+++L+   W   + +  F D  VP+   + E G A+++G+ + + L + G
Sbjct: 121 LGGILSWASGVTALVPVSWVAHKTVQEFWDENVPDFVPRWEFGEALFLGWFAGLSLLLGG 180

Query: 179 -MIFCTSCIKRNPEA 192
            ++ C +C    P A
Sbjct: 181 CLLHCAACSSHAPLA 195


>gi|10938016 claudin 11 [Homo sapiens]
          Length = 207

 Score = 69.7 bits (169), Expect = 2e-12
 Identities = 50/183 (27%), Positives = 84/183 (45%), Gaps = 12/183 (6%)

Query: 1   MASAGLQLLAFILALSGVSGVLTATLLPNWKVNVDVDSNIITAIVQL--HGLWMDCTWYS 58
           M +  LQ++ F+ +  G  GV+  T   +W V           + +L   GLW DC   +
Sbjct: 1   MVATCLQVVGFVTSFVGWIGVIVTTSTNDWVVTCGYTIPTCRKLDELGSKGLWADCVM-A 59

Query: 59  TGMFSCALKHSILSLPIHVQAARATMVLACVLSALGICTSTVGMKCTRLGGD-RETKSHA 117
           TG++ C     IL LP +VQA RA M+ A VL    I      + C R+G +    K   
Sbjct: 60  TGLYHCKPLVDILILPGYVQACRALMIAASVLGLPAILLLLTVLPCIRMGQEPGVAKYRR 119

Query: 118 SFAGGVCFMSAGISSLISTVWYTKEIIANFLDLTVPESNKHEPGGAIYIGFISAMLLFIS 177
           +   GV  +   + +L++T+W+    +    + T+        G ++Y G+I A+L  + 
Sbjct: 120 AQLAGVLLILLALCALVATIWFP---VCAHRETTIVSF-----GYSLYAGWIGAVLCLVG 171

Query: 178 GMI 180
           G +
Sbjct: 172 GCV 174


  Database: hs.faa
    Posted date:  Aug 4, 2009  4:42 PM
  Number of letters in database: 18,247,518
  Number of sequences in database:  37,866
  
Lambda     K      H
   0.322    0.134    0.412 

Gapped
Lambda     K      H
   0.267   0.0410    0.140 


Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Hits to DB: 7,900,962
Number of Sequences: 37866
Number of extensions: 309625
Number of successful extensions: 787
Number of sequences better than 10.0: 30
Number of HSP's better than 10.0 without gapping: 35
Number of HSP's successfully gapped in prelim test: 11
Number of HSP's that attempted gapping in prelim test: 726
Number of HSP's gapped (non-prelim): 47
length of query: 219
length of database: 18,247,518
effective HSP length: 98
effective length of query: 121
effective length of database: 14,536,650
effective search space: 1758934650
effective search space used: 1758934650
T: 11
A: 40
X1: 16 ( 7.4 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 41 (22.0 bits)
S2: 60 (27.7 bits)

Search results were obtained with NCBI BLAST and RefSeq entries.


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Guide to the Human Genome
Copyright © 2010 by Stewart Scherer. All rights reserved.

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