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Search of human proteins with 4759254
BLASTP 2.2.11 [Jun-05-2005]
Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer,
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997),
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs", Nucleic Acids Res. 25:3389-3402.
Query= gi|4759254 TNF receptor-associated factor 6 [Homo sapiens]
(522 letters)
Database: hs.faa
37,866 sequences; 18,247,518 total letters
Searching..................................................done
Score E
Sequences producing significant alignments: (bits) Value
gi|22027630 TNF receptor-associated factor 6 [Homo sapiens] 1093 0.0
gi|4759254 TNF receptor-associated factor 6 [Homo sapiens] 1093 0.0
gi|22027612 TNF receptor-associated factor 2 [Homo sapiens] 198 9e-51
gi|22027622 TNF receptor-associated factor 4 [Homo sapiens] 196 6e-50
gi|22027616 TNF receptor-associated factor 3 isoform 1 [Homo sap... 194 2e-49
gi|22027618 TNF receptor-associated factor 3 isoform 1 [Homo sap... 194 2e-49
gi|22027627 TNF receptor-associated factor 5 [Homo sapiens] 180 3e-45
gi|77404348 TNF receptor-associated factor 5 [Homo sapiens] 180 3e-45
gi|11321603 TNF receptor-associated factor 5 [Homo sapiens] 180 3e-45
gi|22027620 TNF receptor-associated factor 3 isoform 2 [Homo sap... 172 9e-43
gi|5032193 TNF receptor-associated factor 1 [Homo sapiens] 105 1e-22
gi|87241872 ring finger protein 151 [Homo sapiens] 66 9e-11
gi|57529737 PDZ domain containing ring finger 3 [Homo sapiens] 64 4e-10
gi|37588861 ring finger protein 41 isoform 1 [Homo sapiens] 59 8e-09
gi|5032071 ring finger protein 41 isoform 1 [Homo sapiens] 59 8e-09
gi|45594312 TNF receptor-associated factor 7 [Homo sapiens] 57 4e-08
gi|37595555 ring finger protein 125 [Homo sapiens] 57 5e-08
gi|40288191 XIAP associated factor 1 isoform 1 [Homo sapiens] 56 7e-08
gi|148596968 tripartite motif-containing 8 [Homo sapiens] 54 5e-07
gi|40288193 XIAP associated factor 1 isoform 2 [Homo sapiens] 52 2e-06
gi|4557841 recombination activating gene 1 [Homo sapiens] 51 2e-06
gi|187607085 ligand of numb-protein X 1 isoform a [Homo sapiens] 51 2e-06
gi|8923898 zinc finger protein 313 [Homo sapiens] 51 2e-06
gi|117938316 tripartite motif-containing 22 [Homo sapiens] 50 7e-06
gi|148528975 LON peptidase N-terminal domain and ring finger 2 [... 48 2e-05
gi|21359963 ring finger and WD repeat domain 2 isoform a [Homo s... 48 2e-05
gi|50233824 ring finger and WD repeat domain 2 isoform d24 [Homo... 48 2e-05
gi|153070262 meprin A alpha [Homo sapiens] 47 3e-05
gi|87080813 LON peptidase N-terminal domain and ring finger 1 [H... 47 4e-05
gi|20162564 tripartite motif-containing 40 [Homo sapiens] 47 4e-05
>gi|22027630 TNF receptor-associated factor 6 [Homo sapiens]
Length = 522
Score = 1093 bits (2826), Expect = 0.0
Identities = 522/522 (100%), Positives = 522/522 (100%)
Query: 1 MSLLNCENSCGSSQSESDCCVAMASSCSAVTKDDSVGGTASTGNLSSSFMEEIQGYDVEF 60
MSLLNCENSCGSSQSESDCCVAMASSCSAVTKDDSVGGTASTGNLSSSFMEEIQGYDVEF
Sbjct: 1 MSLLNCENSCGSSQSESDCCVAMASSCSAVTKDDSVGGTASTGNLSSSFMEEIQGYDVEF 60
Query: 61 DPPLESKYECPICLMALREAVQTPCGHRFCKACIIKSIRDAGHKCPVDNEILLENQLFPD 120
DPPLESKYECPICLMALREAVQTPCGHRFCKACIIKSIRDAGHKCPVDNEILLENQLFPD
Sbjct: 61 DPPLESKYECPICLMALREAVQTPCGHRFCKACIIKSIRDAGHKCPVDNEILLENQLFPD 120
Query: 121 NFAKREILSLMVKCPNEGCLHKMELRHLEDHQAHCEFALMDCPQCQRPFQKFHINIHILK 180
NFAKREILSLMVKCPNEGCLHKMELRHLEDHQAHCEFALMDCPQCQRPFQKFHINIHILK
Sbjct: 121 NFAKREILSLMVKCPNEGCLHKMELRHLEDHQAHCEFALMDCPQCQRPFQKFHINIHILK 180
Query: 181 DCPRRQVSCDNCAASMAFEDKEIHDQNCPLANVICEYCNTILIREQMPNHYDLDCPTAPI 240
DCPRRQVSCDNCAASMAFEDKEIHDQNCPLANVICEYCNTILIREQMPNHYDLDCPTAPI
Sbjct: 181 DCPRRQVSCDNCAASMAFEDKEIHDQNCPLANVICEYCNTILIREQMPNHYDLDCPTAPI 240
Query: 241 PCTFSTFGCHEKMQRNHLARHLQENTQSHMRMLAQAVHSLSVIPDSGYISEVRNFQETIH 300
PCTFSTFGCHEKMQRNHLARHLQENTQSHMRMLAQAVHSLSVIPDSGYISEVRNFQETIH
Sbjct: 241 PCTFSTFGCHEKMQRNHLARHLQENTQSHMRMLAQAVHSLSVIPDSGYISEVRNFQETIH 300
Query: 301 QLEGRLVRQDHQIRELTAKMETQSMYVSELKRTIRTLEDKVAEIEAQQCNGIYIWKIGNF 360
QLEGRLVRQDHQIRELTAKMETQSMYVSELKRTIRTLEDKVAEIEAQQCNGIYIWKIGNF
Sbjct: 301 QLEGRLVRQDHQIRELTAKMETQSMYVSELKRTIRTLEDKVAEIEAQQCNGIYIWKIGNF 360
Query: 361 GMHLKCQEEEKPVVIHSPGFYTGKPGYKLCMRLHLQLPTAQRCANYISLFVHTMQGEYDS 420
GMHLKCQEEEKPVVIHSPGFYTGKPGYKLCMRLHLQLPTAQRCANYISLFVHTMQGEYDS
Sbjct: 361 GMHLKCQEEEKPVVIHSPGFYTGKPGYKLCMRLHLQLPTAQRCANYISLFVHTMQGEYDS 420
Query: 421 HLPWPFQGTIRLTILDQSEAPVRQNHEEIMDAKPELLAFQRPTIPRNPKGFGYVTFMHLE 480
HLPWPFQGTIRLTILDQSEAPVRQNHEEIMDAKPELLAFQRPTIPRNPKGFGYVTFMHLE
Sbjct: 421 HLPWPFQGTIRLTILDQSEAPVRQNHEEIMDAKPELLAFQRPTIPRNPKGFGYVTFMHLE 480
Query: 481 ALRQRTFIKDDTLLVRCEVSTRFDMGSLRREGFQPRSTDAGV 522
ALRQRTFIKDDTLLVRCEVSTRFDMGSLRREGFQPRSTDAGV
Sbjct: 481 ALRQRTFIKDDTLLVRCEVSTRFDMGSLRREGFQPRSTDAGV 522
>gi|4759254 TNF receptor-associated factor 6 [Homo sapiens]
Length = 522
Score = 1093 bits (2826), Expect = 0.0
Identities = 522/522 (100%), Positives = 522/522 (100%)
Query: 1 MSLLNCENSCGSSQSESDCCVAMASSCSAVTKDDSVGGTASTGNLSSSFMEEIQGYDVEF 60
MSLLNCENSCGSSQSESDCCVAMASSCSAVTKDDSVGGTASTGNLSSSFMEEIQGYDVEF
Sbjct: 1 MSLLNCENSCGSSQSESDCCVAMASSCSAVTKDDSVGGTASTGNLSSSFMEEIQGYDVEF 60
Query: 61 DPPLESKYECPICLMALREAVQTPCGHRFCKACIIKSIRDAGHKCPVDNEILLENQLFPD 120
DPPLESKYECPICLMALREAVQTPCGHRFCKACIIKSIRDAGHKCPVDNEILLENQLFPD
Sbjct: 61 DPPLESKYECPICLMALREAVQTPCGHRFCKACIIKSIRDAGHKCPVDNEILLENQLFPD 120
Query: 121 NFAKREILSLMVKCPNEGCLHKMELRHLEDHQAHCEFALMDCPQCQRPFQKFHINIHILK 180
NFAKREILSLMVKCPNEGCLHKMELRHLEDHQAHCEFALMDCPQCQRPFQKFHINIHILK
Sbjct: 121 NFAKREILSLMVKCPNEGCLHKMELRHLEDHQAHCEFALMDCPQCQRPFQKFHINIHILK 180
Query: 181 DCPRRQVSCDNCAASMAFEDKEIHDQNCPLANVICEYCNTILIREQMPNHYDLDCPTAPI 240
DCPRRQVSCDNCAASMAFEDKEIHDQNCPLANVICEYCNTILIREQMPNHYDLDCPTAPI
Sbjct: 181 DCPRRQVSCDNCAASMAFEDKEIHDQNCPLANVICEYCNTILIREQMPNHYDLDCPTAPI 240
Query: 241 PCTFSTFGCHEKMQRNHLARHLQENTQSHMRMLAQAVHSLSVIPDSGYISEVRNFQETIH 300
PCTFSTFGCHEKMQRNHLARHLQENTQSHMRMLAQAVHSLSVIPDSGYISEVRNFQETIH
Sbjct: 241 PCTFSTFGCHEKMQRNHLARHLQENTQSHMRMLAQAVHSLSVIPDSGYISEVRNFQETIH 300
Query: 301 QLEGRLVRQDHQIRELTAKMETQSMYVSELKRTIRTLEDKVAEIEAQQCNGIYIWKIGNF 360
QLEGRLVRQDHQIRELTAKMETQSMYVSELKRTIRTLEDKVAEIEAQQCNGIYIWKIGNF
Sbjct: 301 QLEGRLVRQDHQIRELTAKMETQSMYVSELKRTIRTLEDKVAEIEAQQCNGIYIWKIGNF 360
Query: 361 GMHLKCQEEEKPVVIHSPGFYTGKPGYKLCMRLHLQLPTAQRCANYISLFVHTMQGEYDS 420
GMHLKCQEEEKPVVIHSPGFYTGKPGYKLCMRLHLQLPTAQRCANYISLFVHTMQGEYDS
Sbjct: 361 GMHLKCQEEEKPVVIHSPGFYTGKPGYKLCMRLHLQLPTAQRCANYISLFVHTMQGEYDS 420
Query: 421 HLPWPFQGTIRLTILDQSEAPVRQNHEEIMDAKPELLAFQRPTIPRNPKGFGYVTFMHLE 480
HLPWPFQGTIRLTILDQSEAPVRQNHEEIMDAKPELLAFQRPTIPRNPKGFGYVTFMHLE
Sbjct: 421 HLPWPFQGTIRLTILDQSEAPVRQNHEEIMDAKPELLAFQRPTIPRNPKGFGYVTFMHLE 480
Query: 481 ALRQRTFIKDDTLLVRCEVSTRFDMGSLRREGFQPRSTDAGV 522
ALRQRTFIKDDTLLVRCEVSTRFDMGSLRREGFQPRSTDAGV
Sbjct: 481 ALRQRTFIKDDTLLVRCEVSTRFDMGSLRREGFQPRSTDAGV 522
>gi|22027612 TNF receptor-associated factor 2 [Homo sapiens]
Length = 501
Score = 198 bits (504), Expect = 9e-51
Identities = 138/478 (28%), Positives = 216/478 (45%), Gaps = 51/478 (10%)
Query: 64 LESKYECPICLMALREAVQTPCGHRFCKACIIKSIRDAGHKCPV---------DNEILLE 114
LE+KY C C LR Q CGHR+C C+ + C IL
Sbjct: 28 LEAKYLCSACRNVLRRPFQAQCGHRYCSFCLASILSSGPQNCAACVHEGIYEEGISILES 87
Query: 115 NQLFPDNFAKREILSLMVKCPNEGCLHKMELRHLED-HQAHCEFALMDCPQCQRPFQKFH 173
+ FPDN A+RE+ SL CP++GC K L+ E H+ C L +CP C+ +
Sbjct: 88 SSAFPDNAARREVESLPAVCPSDGCTWKGTLKEYESCHEGRCPLMLTECPACKGLVRLGE 147
Query: 174 INIHILKDCPRRQVSCDNCAASMAFEDKEIHDQNCPLANVICEYCNTILI-REQMPNHYD 232
H+ +CP R +SC +C A D + H + CP + C+ C I RE+ +H
Sbjct: 148 KERHLEHECPERSLSCRHCRAPCCGADVKAHHEVCPKFPLTCDGCGKKKIPREKFQDHVK 207
Query: 233 LDCPTAPIPCTFSTFGCHEKMQRNHLARHLQENTQSHMRMLAQAV-HSLSVIPDSGYI-- 289
C +PC F GC E ++ H + + H+ ML +V + ++ D +
Sbjct: 208 -TCGKCRVPCRFHAIGCLETVEGEKQQEHEVQWLREHLAMLLSSVLEAKPLLGDQSHAGS 266
Query: 290 ----------SEVRNFQETIHQLEGRLVRQ-------DHQIRELTAKMETQSMYVSELKR 332
+ F+ + L + R Q R K+E S V +L+R
Sbjct: 267 ELLQRCESLEKKTATFENIVCVLNREVERVAMTAEACSRQHRLDQDKIEALSSKVQQLER 326
Query: 333 TI-------RTLEDKVAEIEAQQCNGIYIWKIGNFGMHLKCQEEEKPVVIHSPGFYTGKP 385
+I LE KV E+EA +G++IWKI +F + + I SP FYT +
Sbjct: 327 SIGLKDLAMADLEQKVLEMEASTYDGVFIWKISDFARKRQEAVAGRIPAIFSPAFYTSRY 386
Query: 386 GYKLCMRLHLQLPTAQRCANYISLFVHTMQGEYDSHLPWPFQGTIRLTILDQSEAPVRQN 445
GYK+C+R++L R ++SLF M+G D+ L WPF + L +LDQ+ N
Sbjct: 387 GYKMCLRIYLNGDGTGR-GTHLSLFFVVMKGPNDALLRWPFNQKVTLMLLDQN------N 439
Query: 446 HEEIMDA-KPELL--AFQRPTIPRNPKGFGYVTFMHLEALR-QRTFIKDDTLLVRCEV 499
E ++DA +P++ +FQRP N G F + + + ++++DD + ++ V
Sbjct: 440 REHVIDAFRPDVTSSSFQRPVNDMNIAS-GCPLFCPVSKMEAKNSYVRDDAIFIKAIV 496
>gi|22027622 TNF receptor-associated factor 4 [Homo sapiens]
Length = 470
Score = 196 bits (497), Expect = 6e-50
Identities = 129/482 (26%), Positives = 220/482 (45%), Gaps = 59/482 (12%)
Query: 55 GYDVEFDPPLESKYECPICLMALREAVQ-TPCGHRFCKACIIKSIRDAGHKCPVDNEILL 113
G+D +F + + CP+C +RE VQ + CGHRFC C+ + + + KCP D L
Sbjct: 3 GFDYKFLEKPKRRLLCPLCGKPMREPVQVSTCGHRFCDTCLQEFLSEGVFKCPEDQLPLD 62
Query: 114 ENQLFPDNFAKREILSLMVKC--PNEGCLHKMELRHLEDHQAHCEFALMDCP-QCQRPFQ 170
+++PD + ++L L ++C EGC LRHL+ H C F ++ CP +C
Sbjct: 63 YAKIYPDPELEVQVLGLPIRCIHSEEGCRWSGPLRHLQGHLNTCSFNVIPCPNRCPMKLS 122
Query: 171 KFHINIHILKDCPRRQVSCDNCAASMAFEDKEIHDQNCPLANVICEY-CNTILIREQMPN 229
+ + H+ DCP+R++ C+ C + E E H+ CP +V CE C ++R +
Sbjct: 123 RRDLPAHLQHDCPKRRLKCEFCGCDFSGEAYESHEGMCPQESVYCENKCGARMMRRLLAQ 182
Query: 230 HYDLDCPTAPIPCTFST-------------------FGCHEKMQRNHLARHLQENTQSHM 270
H +CP PCT+ T C + +AR E+ H+
Sbjct: 183 HATSECPKRTQPCTYCTKEFVFDTIQSHQYQCPRLPVACPNQCGVGTVAR---EDLPGHL 239
Query: 271 RMLAQAVHSLSVIPDSGY------ISEVRNFQETIHQLEGRLVRQDHQIRELTAKMETQS 324
+ L DSG ++ R+ +E++ + + A + Q
Sbjct: 240 KDSCNTALVLCPFKDSGCKHRCPKLAMARHVEESVKP----------HLAMMCALVSRQR 289
Query: 325 MYVSELKRTIRTLEDKVAEIEAQQCNGIYIWKIGNFGMHLKCQEEEKPVVIHSPGFYTGK 384
+ EL+R + L + +G+ IWKIG++G L+ + + + SP FYT K
Sbjct: 290 QELQELRRELEEL--------SVGSDGVLIWKIGSYGRRLQEAKAKPNLECFSPAFYTHK 341
Query: 385 PGYKLCMRLHLQLPTAQRCANYISLFVHTMQGEYDSHLPWPFQGTIRLTILDQSEAPVR- 443
GYKL + L ++SL++ + G +D+ L WPF + ++LDQS+ +
Sbjct: 342 YGYKLQVSAFLN-GNGSGEGTHLSLYIRVLPGAFDNLLEWPFARRVTFSLLDQSDPGLAK 400
Query: 444 -QNHEEIMDAKPELLAFQRP-----TIPRNPKGFGYVTFMHLEALRQRTFIKDDTLLVRC 497
Q+ E P FQ+P ++ + GFGY F+ + +R+R +++DD + +R
Sbjct: 401 PQHVTETFHPDPNWKNFQKPGTWRGSLDESSLGFGYPKFISHQDIRKRNYVRDDAVFIRA 460
Query: 498 EV 499
V
Sbjct: 461 AV 462
>gi|22027616 TNF receptor-associated factor 3 isoform 1 [Homo
sapiens]
Length = 568
Score = 194 bits (492), Expect = 2e-49
Identities = 142/536 (26%), Positives = 241/536 (44%), Gaps = 88/536 (16%)
Query: 49 FMEEIQGYDVEFDPPLESKYECPICLMALREAVQTPCGHRFCKACIIKSIRDAGHKCPVD 108
F+ E GY +F +E KY+C C + L QT CGHRFC++C+ + + KC
Sbjct: 32 FVPEQGGYKEKFVKTVEDKYKCEKCHLVLCSPKQTECGHRFCESCMAALLSSSSPKCTAC 91
Query: 109 NEILLENQLFPDNFAKREILSLMVKCPNE--GCLHKMELRHLEDH-QAHCEFALMDC--P 163
E ++++++F DN KREIL+L + C NE GC ++ L HL H + C F + C P
Sbjct: 92 QESIVKDKVFKDNCCKREILALQIYCRNESRGCAEQLMLGHLLVHLKNDCHFEELPCVRP 151
Query: 164 QCQRPFQKFHINIHILKDCPRRQVSCDNCAASMAFEDKEIH-DQNCPLANVICEY-CNT- 220
C+ + + H+ K C R+ +C +C + + + H D +CP V C + C+
Sbjct: 152 DCKEKVLRKDLRDHVEKACKYREATCSHCKSQVPMIALQKHEDTDCPCVVVSCPHKCSVQ 211
Query: 221 ILIREQMPNHYDLDCPTAPIPCTFSTFGCHEKMQRNHLARHLQENTQSHMRMLAQAVHSL 280
L+R ++ H +C AP C+F +GC + + H + H+ +L + +SL
Sbjct: 212 TLLRSELSAHLS-ECVNAPSTCSFKRYGCVFQGTNQQIKAHEASSAVQHVNLLKEWSNSL 270
Query: 281 ----------SVIPDSGYIS---EVRNFQETIHQLEGRLVRQDHQIRELTAKMETQSMYV 327
SV + S ++ +F+ I + + L + +I L +++Q+ +
Sbjct: 271 EKKVSLLQNESVEKNKSIQSLHNQICSFEIEIERQKEMLRNNESKILHLQRVIDSQAEKL 330
Query: 328 SELKRTIR-----------------TLEDKVAEIEA------------------------ 346
EL + IR +L+++V E+E+
Sbjct: 331 KELDKEIRPFRQNWEEADSMKSSVESLQNRVTELESVDKSAGQVARNTGLLESQLSRHDQ 390
Query: 347 ---------------------QQCNGIYIWKIGNFGMHLKCQEEEKPVVIHSPGFYTGKP 385
NG+ IWKI ++ + K + ++S FYTG
Sbjct: 391 MLSVHDIRLADMDLRFQVLETASYNGVLIWKIRDYKRRKQEAVMGKTLSLYSQPFYTGYF 450
Query: 386 GYKLCMRLHLQLPTAQRCANYISLFVHTMQGEYDSHLPWPFQGTIRLTILDQSEAPVRQN 445
GYK+C R++L ++SLF M+GEYD+ LPWPF+ + L ++DQ + R++
Sbjct: 451 GYKMCARVYLN-GDGMGKGTHLSLFFVIMRGEYDALLPWPFKQKVTLMLMDQGSS--RRH 507
Query: 446 HEEIMDAKPELLAFQRPTIPRNPKGFGYVTFMHLEALRQRTFIKDDTLLVRCEVST 501
+ P +F++PT N G F+ L T+IKDDT+ ++ V T
Sbjct: 508 LGDAFKPDPNSSSFKKPTGEMNIAS-GCPVFVAQTVLENGTYIKDDTIFIKVIVDT 562
>gi|22027618 TNF receptor-associated factor 3 isoform 1 [Homo
sapiens]
Length = 568
Score = 194 bits (492), Expect = 2e-49
Identities = 142/536 (26%), Positives = 241/536 (44%), Gaps = 88/536 (16%)
Query: 49 FMEEIQGYDVEFDPPLESKYECPICLMALREAVQTPCGHRFCKACIIKSIRDAGHKCPVD 108
F+ E GY +F +E KY+C C + L QT CGHRFC++C+ + + KC
Sbjct: 32 FVPEQGGYKEKFVKTVEDKYKCEKCHLVLCSPKQTECGHRFCESCMAALLSSSSPKCTAC 91
Query: 109 NEILLENQLFPDNFAKREILSLMVKCPNE--GCLHKMELRHLEDH-QAHCEFALMDC--P 163
E ++++++F DN KREIL+L + C NE GC ++ L HL H + C F + C P
Sbjct: 92 QESIVKDKVFKDNCCKREILALQIYCRNESRGCAEQLMLGHLLVHLKNDCHFEELPCVRP 151
Query: 164 QCQRPFQKFHINIHILKDCPRRQVSCDNCAASMAFEDKEIH-DQNCPLANVICEY-CNT- 220
C+ + + H+ K C R+ +C +C + + + H D +CP V C + C+
Sbjct: 152 DCKEKVLRKDLRDHVEKACKYREATCSHCKSQVPMIALQKHEDTDCPCVVVSCPHKCSVQ 211
Query: 221 ILIREQMPNHYDLDCPTAPIPCTFSTFGCHEKMQRNHLARHLQENTQSHMRMLAQAVHSL 280
L+R ++ H +C AP C+F +GC + + H + H+ +L + +SL
Sbjct: 212 TLLRSELSAHLS-ECVNAPSTCSFKRYGCVFQGTNQQIKAHEASSAVQHVNLLKEWSNSL 270
Query: 281 ----------SVIPDSGYIS---EVRNFQETIHQLEGRLVRQDHQIRELTAKMETQSMYV 327
SV + S ++ +F+ I + + L + +I L +++Q+ +
Sbjct: 271 EKKVSLLQNESVEKNKSIQSLHNQICSFEIEIERQKEMLRNNESKILHLQRVIDSQAEKL 330
Query: 328 SELKRTIR-----------------TLEDKVAEIEA------------------------ 346
EL + IR +L+++V E+E+
Sbjct: 331 KELDKEIRPFRQNWEEADSMKSSVESLQNRVTELESVDKSAGQVARNTGLLESQLSRHDQ 390
Query: 347 ---------------------QQCNGIYIWKIGNFGMHLKCQEEEKPVVIHSPGFYTGKP 385
NG+ IWKI ++ + K + ++S FYTG
Sbjct: 391 MLSVHDIRLADMDLRFQVLETASYNGVLIWKIRDYKRRKQEAVMGKTLSLYSQPFYTGYF 450
Query: 386 GYKLCMRLHLQLPTAQRCANYISLFVHTMQGEYDSHLPWPFQGTIRLTILDQSEAPVRQN 445
GYK+C R++L ++SLF M+GEYD+ LPWPF+ + L ++DQ + R++
Sbjct: 451 GYKMCARVYLN-GDGMGKGTHLSLFFVIMRGEYDALLPWPFKQKVTLMLMDQGSS--RRH 507
Query: 446 HEEIMDAKPELLAFQRPTIPRNPKGFGYVTFMHLEALRQRTFIKDDTLLVRCEVST 501
+ P +F++PT N G F+ L T+IKDDT+ ++ V T
Sbjct: 508 LGDAFKPDPNSSSFKKPTGEMNIAS-GCPVFVAQTVLENGTYIKDDTIFIKVIVDT 562
>gi|22027627 TNF receptor-associated factor 5 [Homo sapiens]
Length = 557
Score = 180 bits (456), Expect = 3e-45
Identities = 143/525 (27%), Positives = 235/525 (44%), Gaps = 89/525 (16%)
Query: 57 DVEFDPPLESKYECPICLMALREAVQTPCGHRFCKACIIKSIRDAGHK--CPVDNEILLE 114
+ +F LE +Y+C C L QT CGHRFC+ CI+ S+R+ CPVD E++
Sbjct: 32 EYQFVERLEERYKCAFCHSVLHNPHQTGCGHRFCQHCIL-SLRELNTVPICPVDKEVIKS 90
Query: 115 NQLFPDNFAKREILSLMVKCPNE-GCLHKMELRHLEDHQAHCEFALMDCP--QCQRPFQK 171
++F DN KRE+L+L V C N GC K+ L +DH C F + C +C+ P +
Sbjct: 91 QEVFKDNCCKREVLNLYVYCSNAPGCNAKVILGRYQDHLQQCLFQPVQCSNEKCREPVLR 150
Query: 172 FHINIHILKDCPRRQVSCDNCAASMAFEDKEIHDQN-CPLANVIC-EYCNTILIREQMPN 229
+ H+ C R+ C C + + + H++N CP V C C I+++ ++
Sbjct: 151 KDLKEHLSASCQFRKEKCLYCKKDVVVINLQNHEENLCPEYPVFCPNNCAKIILKTEVDE 210
Query: 230 HYDLDCPTAPIPCTFSTFGCHEKMQRNHLARH------------LQENTQ---------- 267
H + CP A C F +GC +R +L +H L++N Q
Sbjct: 211 HLAV-CPEAEQDCPFKHYGCAVTDKRRNLQQHEHSALREHMRLVLEKNVQLEEQISDLHK 269
Query: 268 ------SHMRMLAQAVHSL---------------SVIPD----SGYISEVRNFQETIHQL 302
S ++ LA+ + L S +P+ + +I + + +HQL
Sbjct: 270 SLEQKESKIQQLAETIKKLEKEFKQFAQLFGKNGSFLPNIQVFASHIDKSAWLEAQVHQL 329
Query: 303 EGRLVRQDHQ--IRELTAKMETQSMYVSELKRTIRTL----------------------- 337
+ +Q ++ +R L ++T ++ L+ + L
Sbjct: 330 LQMVNQQQNKFDLRPLMEAVDTVKQKITLLENNDQRLAVLEEETNKHDTHINIHKAQLSK 389
Query: 338 -EDKVAEIEAQQCNGIYIWKIGNFGMHLKCQEEEKPVVIHSPGFYTGKPGYKLCMRLHLQ 396
E++ +E NG IWK+ ++ M + + V I S FYT + GY+LC R +L
Sbjct: 390 NEERFKLLEGTCYNGKLIWKVTDYKMKKREAVDGHTVSIFSQSFYTSRCGYRLCARAYLN 449
Query: 397 LPTAQRCANYISLFVHTMQGEYDSHLPWPFQGTIRLTILDQSEAPVRQNHEEIMDAKPEL 456
+ R +++SL+ M+GE+DS L WPF+ + L +LDQS ++N E P
Sbjct: 450 GDGSGR-GSHLSLYFVVMRGEFDSLLQWPFRQRVTLMLLDQSG---KKNIMETFKPDPNS 505
Query: 457 LAFQRPTIPRNPKGFGYVTFMHLEALR--QRTFIKDDTLLVRCEV 499
+F+RP N G F+ L + +IKDDTL ++ V
Sbjct: 506 SSFKRPDGEMNIAS-GCPRFVAHSVLENAKNAYIKDDTLFLKVAV 549
>gi|77404348 TNF receptor-associated factor 5 [Homo sapiens]
Length = 557
Score = 180 bits (456), Expect = 3e-45
Identities = 143/525 (27%), Positives = 235/525 (44%), Gaps = 89/525 (16%)
Query: 57 DVEFDPPLESKYECPICLMALREAVQTPCGHRFCKACIIKSIRDAGHK--CPVDNEILLE 114
+ +F LE +Y+C C L QT CGHRFC+ CI+ S+R+ CPVD E++
Sbjct: 32 EYQFVERLEERYKCAFCHSVLHNPHQTGCGHRFCQHCIL-SLRELNTVPICPVDKEVIKS 90
Query: 115 NQLFPDNFAKREILSLMVKCPNE-GCLHKMELRHLEDHQAHCEFALMDCP--QCQRPFQK 171
++F DN KRE+L+L V C N GC K+ L +DH C F + C +C+ P +
Sbjct: 91 QEVFKDNCCKREVLNLYVYCSNAPGCNAKVILGRYQDHLQQCLFQPVQCSNEKCREPVLR 150
Query: 172 FHINIHILKDCPRRQVSCDNCAASMAFEDKEIHDQN-CPLANVIC-EYCNTILIREQMPN 229
+ H+ C R+ C C + + + H++N CP V C C I+++ ++
Sbjct: 151 KDLKEHLSASCQFRKEKCLYCKKDVVVINLQNHEENLCPEYPVFCPNNCAKIILKTEVDE 210
Query: 230 HYDLDCPTAPIPCTFSTFGCHEKMQRNHLARH------------LQENTQ---------- 267
H + CP A C F +GC +R +L +H L++N Q
Sbjct: 211 HLAV-CPEAEQDCPFKHYGCAVTDKRRNLQQHEHSALREHMRLVLEKNVQLEEQISDLHK 269
Query: 268 ------SHMRMLAQAVHSL---------------SVIPD----SGYISEVRNFQETIHQL 302
S ++ LA+ + L S +P+ + +I + + +HQL
Sbjct: 270 SLEQKESKIQQLAETIKKLEKEFKQFAQLFGKNGSFLPNIQVFASHIDKSAWLEAQVHQL 329
Query: 303 EGRLVRQDHQ--IRELTAKMETQSMYVSELKRTIRTL----------------------- 337
+ +Q ++ +R L ++T ++ L+ + L
Sbjct: 330 LQMVNQQQNKFDLRPLMEAVDTVKQKITLLENNDQRLAVLEEETNKHDTHINIHKAQLSK 389
Query: 338 -EDKVAEIEAQQCNGIYIWKIGNFGMHLKCQEEEKPVVIHSPGFYTGKPGYKLCMRLHLQ 396
E++ +E NG IWK+ ++ M + + V I S FYT + GY+LC R +L
Sbjct: 390 NEERFKLLEGTCYNGKLIWKVTDYKMKKREAVDGHTVSIFSQSFYTSRCGYRLCARAYLN 449
Query: 397 LPTAQRCANYISLFVHTMQGEYDSHLPWPFQGTIRLTILDQSEAPVRQNHEEIMDAKPEL 456
+ R +++SL+ M+GE+DS L WPF+ + L +LDQS ++N E P
Sbjct: 450 GDGSGR-GSHLSLYFVVMRGEFDSLLQWPFRQRVTLMLLDQSG---KKNIMETFKPDPNS 505
Query: 457 LAFQRPTIPRNPKGFGYVTFMHLEALR--QRTFIKDDTLLVRCEV 499
+F+RP N G F+ L + +IKDDTL ++ V
Sbjct: 506 SSFKRPDGEMNIAS-GCPRFVAHSVLENAKNAYIKDDTLFLKVAV 549
>gi|11321603 TNF receptor-associated factor 5 [Homo sapiens]
Length = 557
Score = 180 bits (456), Expect = 3e-45
Identities = 143/525 (27%), Positives = 235/525 (44%), Gaps = 89/525 (16%)
Query: 57 DVEFDPPLESKYECPICLMALREAVQTPCGHRFCKACIIKSIRDAGHK--CPVDNEILLE 114
+ +F LE +Y+C C L QT CGHRFC+ CI+ S+R+ CPVD E++
Sbjct: 32 EYQFVERLEERYKCAFCHSVLHNPHQTGCGHRFCQHCIL-SLRELNTVPICPVDKEVIKS 90
Query: 115 NQLFPDNFAKREILSLMVKCPNE-GCLHKMELRHLEDHQAHCEFALMDCP--QCQRPFQK 171
++F DN KRE+L+L V C N GC K+ L +DH C F + C +C+ P +
Sbjct: 91 QEVFKDNCCKREVLNLYVYCSNAPGCNAKVILGRYQDHLQQCLFQPVQCSNEKCREPVLR 150
Query: 172 FHINIHILKDCPRRQVSCDNCAASMAFEDKEIHDQN-CPLANVIC-EYCNTILIREQMPN 229
+ H+ C R+ C C + + + H++N CP V C C I+++ ++
Sbjct: 151 KDLKEHLSASCQFRKEKCLYCKKDVVVINLQNHEENLCPEYPVFCPNNCAKIILKTEVDE 210
Query: 230 HYDLDCPTAPIPCTFSTFGCHEKMQRNHLARH------------LQENTQ---------- 267
H + CP A C F +GC +R +L +H L++N Q
Sbjct: 211 HLAV-CPEAEQDCPFKHYGCAVTDKRRNLQQHEHSALREHMRLVLEKNVQLEEQISDLHK 269
Query: 268 ------SHMRMLAQAVHSL---------------SVIPD----SGYISEVRNFQETIHQL 302
S ++ LA+ + L S +P+ + +I + + +HQL
Sbjct: 270 SLEQKESKIQQLAETIKKLEKEFKQFAQLFGKNGSFLPNIQVFASHIDKSAWLEAQVHQL 329
Query: 303 EGRLVRQDHQ--IRELTAKMETQSMYVSELKRTIRTL----------------------- 337
+ +Q ++ +R L ++T ++ L+ + L
Sbjct: 330 LQMVNQQQNKFDLRPLMEAVDTVKQKITLLENNDQRLAVLEEETNKHDTHINIHKAQLSK 389
Query: 338 -EDKVAEIEAQQCNGIYIWKIGNFGMHLKCQEEEKPVVIHSPGFYTGKPGYKLCMRLHLQ 396
E++ +E NG IWK+ ++ M + + V I S FYT + GY+LC R +L
Sbjct: 390 NEERFKLLEGTCYNGKLIWKVTDYKMKKREAVDGHTVSIFSQSFYTSRCGYRLCARAYLN 449
Query: 397 LPTAQRCANYISLFVHTMQGEYDSHLPWPFQGTIRLTILDQSEAPVRQNHEEIMDAKPEL 456
+ R +++SL+ M+GE+DS L WPF+ + L +LDQS ++N E P
Sbjct: 450 GDGSGR-GSHLSLYFVVMRGEFDSLLQWPFRQRVTLMLLDQSG---KKNIMETFKPDPNS 505
Query: 457 LAFQRPTIPRNPKGFGYVTFMHLEALR--QRTFIKDDTLLVRCEV 499
+F+RP N G F+ L + +IKDDTL ++ V
Sbjct: 506 SSFKRPDGEMNIAS-GCPRFVAHSVLENAKNAYIKDDTLFLKVAV 549
>gi|22027620 TNF receptor-associated factor 3 isoform 2 [Homo
sapiens]
Length = 543
Score = 172 bits (435), Expect = 9e-43
Identities = 136/515 (26%), Positives = 229/515 (44%), Gaps = 71/515 (13%)
Query: 49 FMEEIQGYDVEFDPPLESKYECPICLMALREAVQTPCGHRFCKACIIKSIRDAGHKCPVD 108
F+ E GY +F +E KY+C C + L QT CGHRFC++C+ + + KC
Sbjct: 32 FVPEQGGYKEKFVKTVEDKYKCEKCHLVLCSPKQTECGHRFCESCMAALLSSSSPKCTAC 91
Query: 109 NEILLENQLFPDNFAKREILSLMVKCPNE--GCLHKMELRHLEDHQAH-CEFALMDC--P 163
E ++++++F DN KREIL+L + C NE GC ++ L HL H + C F + C P
Sbjct: 92 QESIVKDKVFKDNCCKREILALQIYCRNESRGCAEQLMLGHLLVHLKNDCHFEELPCVRP 151
Query: 164 QCQRPFQKFHINIHILKDCPRRQVSCDNCAASMAFEDKEIH-DQNCPLANVIC------- 215
C+ + + H+ K C R+ +C +C + + + H D +CP V C
Sbjct: 152 DCKEKVLRKDLRDHVEKACKYREATCSHCKSQVPMIALQKHEDTDCPCVVVSCPHKCSVQ 211
Query: 216 ----------------------------EYCNTI------LIREQMPNHYDLDCPTAPIP 241
E+ N++ L E + + + I
Sbjct: 212 TLLRSEGTNQQIKAHEASSAVQHVNLLKEWSNSLEKKVSLLQNESVEKNKSIQSLHNQI- 270
Query: 242 CTFST-FGCHEKMQRNHLAR--HLQENTQSHMRMLAQAVHSLSVIPDSGYISEVRNFQET 298
C+F ++M RN+ ++ HLQ S L + + P E + + +
Sbjct: 271 CSFEIEIERQKEMLRNNESKILHLQRVIDSQAEKLKEL--DKEIRPFRQNWEEADSMKSS 328
Query: 299 IHQLEGRLVRQDH------QIRELTAKMETQ------SMYVSELKRTIRTLEDKVAEIEA 346
+ L+ R+ + Q+ T +E+Q + V +++ L +V +E
Sbjct: 329 VESLQNRVTELESVDKSAGQVARNTGLLESQLSRHDQMLSVHDIRLADMDLRFQV--LET 386
Query: 347 QQCNGIYIWKIGNFGMHLKCQEEEKPVVIHSPGFYTGKPGYKLCMRLHLQLPTAQRCANY 406
NG+ IWKI ++ + K + ++S FYTG GYK+C R++L +
Sbjct: 387 ASYNGVLIWKIRDYKRRKQEAVMGKTLSLYSQPFYTGYFGYKMCARVYLN-GDGMGKGTH 445
Query: 407 ISLFVHTMQGEYDSHLPWPFQGTIRLTILDQSEAPVRQNHEEIMDAKPELLAFQRPTIPR 466
+SLF M+GEYD+ LPWPF+ + L ++DQ + R++ + P +F++PT
Sbjct: 446 LSLFFVIMRGEYDALLPWPFKQKVTLMLMDQGSS--RRHLGDAFKPDPNSSSFKKPTGEM 503
Query: 467 NPKGFGYVTFMHLEALRQRTFIKDDTLLVRCEVST 501
N G F+ L T+IKDDT+ ++ V T
Sbjct: 504 NIAS-GCPVFVAQTVLENGTYIKDDTIFIKVIVDT 537
>gi|5032193 TNF receptor-associated factor 1 [Homo sapiens]
Length = 416
Score = 105 bits (261), Expect = 1e-22
Identities = 79/281 (28%), Positives = 139/281 (49%), Gaps = 38/281 (13%)
Query: 232 DLDCPTAPIPCTFSTFGCHEKMQRNHLARHLQENTQSHMRMLAQAVHSLSVIPDSGYISE 291
++DC AP C E + L ++E + + + ++ + + +
Sbjct: 161 EVDCYRAP---------CSESQEELALQHFMKEKLLAELEGKLRVFENIVAVLNKEVEAS 211
Query: 292 VRNFQETIHQLE---GRLVRQDHQIRELTAKMETQSMYVSELKRTIRTLEDKVAEIEAQQ 348
+IHQ + R++ + ++ EL + + + +L++++R +E+
Sbjct: 212 HLALATSIHQSQLDRERILSLEQRVVELQQTLAQKDQALGKLEQSLRLMEEA-------S 264
Query: 349 CNGIYIWKIGNFGMHLKCQEEE--KPVVIHSPGFYTGKPGYKLCMRLHLQLP-TAQRCAN 405
+G ++WKI N + +C E + V + SP FYT K GYKLC+RL+L T +R
Sbjct: 265 FDGTFLWKITN--VTRRCHESACGRTVSLFSPAFYTAKYGYKLCLRLYLNGDGTGKR--T 320
Query: 406 YISLFVHTMQGEYDSHLPWPFQGTIRLTILDQSEAPVRQNHEEIMDA-KPEL--LAFQRP 462
++SLF+ M+GEYD+ LPWPF+ + +LDQ+ N E +DA +P+L +FQRP
Sbjct: 321 HLSLFIVIMRGEYDALLPWPFRNKVTFMLLDQN------NREHAIDAFRPDLSSASFQRP 374
Query: 463 TIPRNPKGFGYVTFMHLEALR--QRTFIKDDTLLVRCEVST 501
N G F L L+ + ++KDDT+ ++C V T
Sbjct: 375 QSETNVAS-GCPLFFPLSKLQSPKHAYVKDDTMFLKCIVET 414
>gi|87241872 ring finger protein 151 [Homo sapiens]
Length = 245
Score = 65.9 bits (159), Expect = 9e-11
Identities = 37/112 (33%), Positives = 54/112 (48%), Gaps = 4/112 (3%)
Query: 55 GYDVE-FDPPLESKYECPICLMALREAVQTPCGHRFCKACIIKSIRDAGHKCPVDNEILL 113
GYD+ F P +S + C +C L+ + PC H FCK CI++ + CP + +
Sbjct: 4 GYDLNLFASPPDSNFVCSVCHGVLKRPARLPCSHIFCKKCILRWLA-RQKTCPCCRKEVK 62
Query: 114 ENQLFPDNFAKREILSLMVKCPN--EGCLHKMELRHLEDHQAHCEFALMDCP 163
++ N ++ I L VKC N GC+ L H + HQ C F L CP
Sbjct: 63 RKKVVHMNKLRKTIGRLEVKCKNADAGCIVTCPLAHRKGHQDSCPFELTACP 114
>gi|57529737 PDZ domain containing ring finger 3 [Homo sapiens]
Length = 1066
Score = 63.5 bits (153), Expect = 4e-10
Identities = 43/144 (29%), Positives = 64/144 (44%), Gaps = 16/144 (11%)
Query: 52 EIQGYDVEFDPPLESKYECPICLMALREAVQTPCGHRFCKACIIKSIRDAGHKCPVDNEI 111
E+ +D + DP L+ C +C L + + TPCGH FC C++ + G CP
Sbjct: 4 ELDRFDGDVDPDLK----CALCHKVLEDPLTTPCGHVFCAGCVLPWVVQEG-SCPARCRG 58
Query: 112 LLE----NQLFPDNFAKREILSLMVKC--PNEGCLHKMELRHLEDHQAHCEFALMDCPQ- 164
L N + P KR IL L +KC GC ++L+ L +H C+FA C
Sbjct: 59 RLSAKELNHVLP---LKRLILKLDIKCAYATRGCGRVVKLQQLPEHLERCDFAPARCRHA 115
Query: 165 -CQRPFQKFHINIHILKDCPRRQV 187
C + + + H+ C R V
Sbjct: 116 GCGQVLLRRDVEAHMRDACDARPV 139
>gi|37588861 ring finger protein 41 isoform 1 [Homo sapiens]
Length = 317
Score = 59.3 bits (142), Expect = 8e-09
Identities = 40/107 (37%), Positives = 50/107 (46%), Gaps = 6/107 (5%)
Query: 55 GYDV-EFDPPLESKYECPICLMALREAVQTP-CGHRFCKACIIKSIRDAGHKCPVDNEIL 112
GYDV F ++ CPIC L E VQ P C H FC ACI + CPVD ++
Sbjct: 2 GYDVTRFQGDVDEDLICPICSGVLEEPVQAPHCEHAFCNACITQWFSQQ-QTCPVDRSVV 60
Query: 113 LENQLFPDNFAKREILS-LMVKCPNE--GCLHKMELRHLEDHQAHCE 156
L P R +LS L + C N GC + L +L H + CE
Sbjct: 61 TVAHLRPVPRIMRNMLSKLQIACDNAVFGCSAVVRLDNLMSHLSDCE 107
>gi|5032071 ring finger protein 41 isoform 1 [Homo sapiens]
Length = 317
Score = 59.3 bits (142), Expect = 8e-09
Identities = 40/107 (37%), Positives = 50/107 (46%), Gaps = 6/107 (5%)
Query: 55 GYDV-EFDPPLESKYECPICLMALREAVQTP-CGHRFCKACIIKSIRDAGHKCPVDNEIL 112
GYDV F ++ CPIC L E VQ P C H FC ACI + CPVD ++
Sbjct: 2 GYDVTRFQGDVDEDLICPICSGVLEEPVQAPHCEHAFCNACITQWFSQQ-QTCPVDRSVV 60
Query: 113 LENQLFPDNFAKREILS-LMVKCPNE--GCLHKMELRHLEDHQAHCE 156
L P R +LS L + C N GC + L +L H + CE
Sbjct: 61 TVAHLRPVPRIMRNMLSKLQIACDNAVFGCSAVVRLDNLMSHLSDCE 107
>gi|45594312 TNF receptor-associated factor 7 [Homo sapiens]
Length = 670
Score = 57.0 bits (136), Expect = 4e-08
Identities = 51/196 (26%), Positives = 82/196 (41%), Gaps = 40/196 (20%)
Query: 41 STGNLSSSFM---EEIQGYDVEFDPPLESKYECPICLMALREAVQTPCGHRFCKACIIKS 97
S+ +L S+F EE + + F K C +C ++ V T CGH FC+ C +KS
Sbjct: 99 SSMSLRSTFSLPEEEEEPEPLVFAEQPSVKLCCQLCCSVFKDPVITTCGHTFCRRCALKS 158
Query: 98 IRDAGHKCPVDNEILLENQLFPDNFAKRE-ILSLMVKCPN-----------------EGC 139
KCPVDN ++ + +N A E I L + C + GC
Sbjct: 159 -----EKCPVDN---VKLTVVVNNIAVAEQIGELFIHCRHGCRVAGSGKPPIFEVDPRGC 210
Query: 140 LHKMELRHLEDHQAHCEFALMDC---PQCQRPFQKFHINIHILKDCPRRQVSCDNCAASM 196
++L +DH+ C++ + C P C P + ++ H LK+C + C +
Sbjct: 211 PFTIKLSARKDHEGSCDYRPVRCPNNPSCP-PLLRMNLEAH-LKEC--EHIKCPHSKYGC 266
Query: 197 AF----EDKEIHDQNC 208
F + E H + C
Sbjct: 267 TFIGNQDTYETHLETC 282
>gi|37595555 ring finger protein 125 [Homo sapiens]
Length = 232
Score = 56.6 bits (135), Expect = 5e-08
Identities = 43/152 (28%), Positives = 63/152 (41%), Gaps = 25/152 (16%)
Query: 61 DPPLE-SKYECPICLMALREAVQTPCGHRFCKACIIKSIRDAGHKCPVDNEILLENQLFP 119
DP L + ++C +CL L + V+T CGH FC++CI S+++ CP L +
Sbjct: 27 DPELPVTSFDCAVCLEVLHQPVRTRCGHVFCRSCIATSLKNNKWTCPYCRAYLPSEGVPA 86
Query: 120 DNFAKR--EILSLMVKCPNEGCLHKME---------------LRHLEDHQAHCEFALMDC 162
+ AKR +C CL +M L+ LE+ A C C
Sbjct: 87 TDVAKRMKSEYKNCAECDTLVCLSEMRAHIRTCQKYIDKYGPLQELEETAARCV-----C 141
Query: 163 PQCQRPFQKFHINIHILKD--CPRRQVSCDNC 192
P CQR + + H + RR V C C
Sbjct: 142 PFCQRELYEDSLLDHCITHHRSERRPVFCPLC 173
>gi|40288191 XIAP associated factor 1 isoform 1 [Homo sapiens]
Length = 301
Score = 56.2 bits (134), Expect = 7e-08
Identities = 30/115 (26%), Positives = 46/115 (40%), Gaps = 5/115 (4%)
Query: 121 NFAKREI--LSLMVKCPNEGCLHKMELRHLEDHQAHCEFALMDCPQCQRPFQKFHINIHI 178
NF E L +V CP C + +E+H E + C CQ+ QK + H
Sbjct: 19 NFTLHEAYCLRFLVLCPE--CEEPVPKETMEEH-CKLEHQQVGCTMCQQSMQKSSLEFHK 75
Query: 179 LKDCPRRQVSCDNCAASMAFEDKEIHDQNCPLANVICEYCNTILIREQMPNHYDL 233
+C R V C C M E+H+ C +C+ C ++ + H D+
Sbjct: 76 ANECQERPVECKFCKLDMQLSKLELHESYCGSRTELCQGCGQFIMHRMLAQHRDV 130
Score = 32.7 bits (73), Expect = 0.83
Identities = 20/79 (25%), Positives = 32/79 (40%), Gaps = 6/79 (7%)
Query: 189 CDNCAASMAFEDKEIHDQNCPLANVICEYCNTILIREQMPNHYDLDCPTAPIPCTFSTFG 248
C NC + + +H+ C V+C C + +E M H L+ + CT
Sbjct: 8 CRNCKRHVVSANFTLHEAYCLRFLVLCPECEEPVPKETMEEHCKLE--HQQVGCTM---- 61
Query: 249 CHEKMQRNHLARHLQENTQ 267
C + MQ++ L H Q
Sbjct: 62 CQQSMQKSSLEFHKANECQ 80
>gi|148596968 tripartite motif-containing 8 [Homo sapiens]
Length = 551
Score = 53.5 bits (127), Expect = 5e-07
Identities = 46/170 (27%), Positives = 71/170 (41%), Gaps = 28/170 (16%)
Query: 65 ESKYECPICLMALREAVQTPCGHRFCKACIIKS-IRDAG-HKCPVDNEILLENQLFPDNF 122
E + CPICL E VQ PC H FC+ CI ++ +D+G +CP N+ +
Sbjct: 10 EEELICPICLHVFVEPVQLPCKHNFCRGCIGEAWAKDSGLVRCPECNQA----------Y 59
Query: 123 AKREILSLMVKCPNEGCLHKMELRHLEDHQA--HCEF--------ALMDCPQCQRPFQKF 172
++ L +K N + K H+E A HC F A C +C+ P +
Sbjct: 60 NQKPGLEKNLKLTN--IVEKFNALHVEKPPAALHCVFCRRGPPLPAQKVCLRCEAPCCQS 117
Query: 173 HINIHILKDCPRR---QVSCDNCAASMAFEDKEIHDQNCPLANV-ICEYC 218
H+ H+ + R V D+ A + +C V +C+YC
Sbjct: 118 HVQTHLQQPSTARGHLLVEADDVRAWSCPQHNAYRLYHCEAEQVAVCQYC 167
>gi|40288193 XIAP associated factor 1 isoform 2 [Homo sapiens]
Length = 282
Score = 51.6 bits (122), Expect = 2e-06
Identities = 23/89 (25%), Positives = 38/89 (42%), Gaps = 6/89 (6%)
Query: 151 HQAHCEFALMDCPQCQRPFQKFHINIHI------LKDCPRRQVSCDNCAASMAFEDKEIH 204
H+A+C L+ CP+C+ P K + H +C R V C C M E+H
Sbjct: 23 HEAYCLRFLVLCPECEEPVPKETMEEHCKLEHQQANECQERPVECKFCKLDMQLSKLELH 82
Query: 205 DQNCPLANVICEYCNTILIREQMPNHYDL 233
+ C +C+ C ++ + H D+
Sbjct: 83 ESYCGSRTELCQGCGQFIMHRMLAQHRDV 111
Score = 33.9 bits (76), Expect = 0.37
Identities = 21/79 (26%), Positives = 31/79 (39%), Gaps = 10/79 (12%)
Query: 189 CDNCAASMAFEDKEIHDQNCPLANVICEYCNTILIREQMPNHYDL------DCPTAPIPC 242
C NC + + +H+ C V+C C + +E M H L +C P+ C
Sbjct: 8 CRNCKRHVVSANFTLHEAYCLRFLVLCPECEEPVPKETMEEHCKLEHQQANECQERPVEC 67
Query: 243 TFSTFGCHEKMQRNHLARH 261
F C MQ + L H
Sbjct: 68 KF----CKLDMQLSKLELH 82
>gi|4557841 recombination activating gene 1 [Homo sapiens]
Length = 1043
Score = 51.2 bits (121), Expect = 2e-06
Identities = 29/95 (30%), Positives = 41/95 (43%), Gaps = 1/95 (1%)
Query: 58 VEFDPPLESKYECPICLMALREAVQTPCGHRFCKACIIKSIRDAGHKCPVDNEILLENQL 117
V+F C IC L + V+T C H FC+ CI++ ++ G CP L
Sbjct: 281 VDFPEHFVKSISCQICEHILADPVETNCKHVFCRVCILRCLKVMGSYCPSCRYPCFPTDL 340
Query: 118 -FPDNFAKREILSLMVKCPNEGCLHKMELRHLEDH 151
P + SLMVKCP + C ++ L H
Sbjct: 341 ESPVKSFLSVLNSLMVKCPAKECNEEVSLEKYNHH 375
>gi|187607085 ligand of numb-protein X 1 isoform a [Homo sapiens]
Length = 728
Score = 51.2 bits (121), Expect = 2e-06
Identities = 30/92 (32%), Positives = 47/92 (51%), Gaps = 4/92 (4%)
Query: 70 CPICLMALREAVQTPCGHRFCKACIIKSIRDAGHKCPVDNEILLENQLFPDNFAKREILS 129
C ICL AL + + TPCGH +C C+ + + CP+D + L+ + ++L+
Sbjct: 41 CHICLQALLDPLDTPCGHTYCTLCLTNFLVEKDF-CPMDRKPLVLQHCKKSSILVNKLLN 99
Query: 130 -LMVKCP-NEGCLHKMELRHLEDH-QAHCEFA 158
L+V CP E C ++ LE H Q C+ A
Sbjct: 100 KLLVTCPFREHCTQVLQRCDLEHHFQTSCKGA 131
>gi|8923898 zinc finger protein 313 [Homo sapiens]
Length = 228
Score = 51.2 bits (121), Expect = 2e-06
Identities = 31/104 (29%), Positives = 45/104 (43%), Gaps = 6/104 (5%)
Query: 52 EIQGYDVEFDPPLESKYECPICLMALREAVQTPCGHRFCKACIIKSIRDAGHKCPVDNEI 111
++ G E DP ++ CP+CL + VQ PCGH FC AC+ + ++ C V
Sbjct: 13 QLAGPAAEADPL--GRFTCPVCLEVYEKPVQVPCGHVFCSACLQECLKPKKPVCGVCRSA 70
Query: 112 LLENQLFPDNFAKREILSLMVKCPNEGCLHKMELRHLEDHQAHC 155
L + +R+I S C GC L + H A C
Sbjct: 71 LAPGVRAVE--LERQIESTETSC--HGCRKNFFLSKIRSHVATC 110
>gi|117938316 tripartite motif-containing 22 [Homo sapiens]
Length = 498
Score = 49.7 bits (117), Expect = 7e-06
Identities = 39/138 (28%), Positives = 60/138 (43%), Gaps = 19/138 (13%)
Query: 64 LESKYECPICLMALREAVQTPCGHRFCKACIIKSIRDA------GHKCPVDNEILLENQL 117
+E + CPICL L E + CGH FC+ACI I+++ CPV L
Sbjct: 9 IEKEVTCPICLELLTEPLSLDCGHSFCQACITAKIKESVIISRGESSCPVCQTRFQPGNL 68
Query: 118 FPDNFAKR--EILSLMVKCPNEG-----CLH---KMELRHLEDHQAHCEFALMDCPQCQR 167
P+ E + + P EG C H K+++ ED + C + + Q +
Sbjct: 69 RPNRHLANIVERVKEVKMSPQEGQKRDVCEHHGKKLQIFCKEDGKVIC--WVCELSQEHQ 126
Query: 168 PFQKFHINIHILKDCPRR 185
Q F IN ++K+C +
Sbjct: 127 GHQTFRIN-EVVKECQEK 143
>gi|148528975 LON peptidase N-terminal domain and ring finger 2
[Homo sapiens]
Length = 754
Score = 47.8 bits (112), Expect = 2e-05
Identities = 25/68 (36%), Positives = 37/68 (54%), Gaps = 6/68 (8%)
Query: 47 SSFMEEIQGYDVEFDPPLESKYECPICLMALREAVQTPCGHRFCKACIIKSIRDAGHKCP 106
+S EE QG ++ + +EC +C+ L E V TPCGH FC C+ + + A H CP
Sbjct: 431 NSETEESQGLSLDV-----TDFECALCMRLLFEPVTTPCGHTFCLKCLERCLDHAPH-CP 484
Query: 107 VDNEILLE 114
+ + L E
Sbjct: 485 LCKDKLSE 492
Score = 30.0 bits (66), Expect = 5.4
Identities = 11/25 (44%), Positives = 13/25 (52%)
Query: 70 CPICLMALREAVQTPCGHRFCKACI 94
CP C L + V PCG CK C+
Sbjct: 143 CPRCRRLLHKPVTLPCGLTVCKRCV 167
>gi|21359963 ring finger and WD repeat domain 2 isoform a [Homo
sapiens]
Length = 731
Score = 47.8 bits (112), Expect = 2e-05
Identities = 24/62 (38%), Positives = 36/62 (58%), Gaps = 3/62 (4%)
Query: 68 YECPICLMALREAVQTPCGHRFCKACIIKSIRDAGHKCPVDNEILLE-NQLFPDNFAKRE 126
+ CPIC + EA T CGH FC CI +S+ D ++CP N ++ + L+P NF E
Sbjct: 134 FVCPICFDMIEEAYMTKCGHSFCYKCIHQSLED-NNRCPKCNYVVDNIDHLYP-NFLVNE 191
Query: 127 IL 128
++
Sbjct: 192 LI 193
>gi|50233824 ring finger and WD repeat domain 2 isoform d24 [Homo
sapiens]
Length = 707
Score = 47.8 bits (112), Expect = 2e-05
Identities = 24/62 (38%), Positives = 36/62 (58%), Gaps = 3/62 (4%)
Query: 68 YECPICLMALREAVQTPCGHRFCKACIIKSIRDAGHKCPVDNEILLE-NQLFPDNFAKRE 126
+ CPIC + EA T CGH FC CI +S+ D ++CP N ++ + L+P NF E
Sbjct: 134 FVCPICFDMIEEAYMTKCGHSFCYKCIHQSLED-NNRCPKCNYVVDNIDHLYP-NFLVNE 191
Query: 127 IL 128
++
Sbjct: 192 LI 193
>gi|153070262 meprin A alpha [Homo sapiens]
Length = 746
Score = 47.4 bits (111), Expect = 3e-05
Identities = 44/162 (27%), Positives = 73/162 (45%), Gaps = 27/162 (16%)
Query: 354 IWKIGNFGMHLKCQEEEKPVVIHSPGFYTGKPGYKLCMRLHLQLPTAQRCANYISLFVHT 413
+W + NF L + K + SP FY + GY + L+ P ++ + Y+ L H
Sbjct: 435 VWTVRNFSQVL--ENTSKGDKLQSPRFYNSE-GYGFGVTLY---PNSRESSGYLRLAFHV 488
Query: 414 MQGEYDSHLPWPFQG-TIRLTILDQSEAPVRQNHEEIM----------DAKPELLAFQRP 462
GE D+ L WP + + +TILDQ E VR M A + + + RP
Sbjct: 489 CSGENDAILEWPVENRQVIITILDQ-EPDVRNRMSSSMVFTTSKSHTSPAINDTVIWDRP 547
Query: 463 ----TIPRNPKGF-----GYVTFMHLEALRQRTFIKDDTLLV 495
T + F G+ F+ + L++R+F+K+D L++
Sbjct: 548 SRVGTYHTDCNCFRSIDLGWSGFISHQMLKRRSFLKNDDLII 589
>gi|87080813 LON peptidase N-terminal domain and ring finger 1 [Homo
sapiens]
Length = 773
Score = 47.0 bits (110), Expect = 4e-05
Identities = 21/49 (42%), Positives = 29/49 (59%), Gaps = 1/49 (2%)
Query: 66 SKYECPICLMALREAVQTPCGHRFCKACIIKSIRDAGHKCPVDNEILLE 114
S +EC +C+ E V TPCGH FCK C+ + + A + CP+ E L E
Sbjct: 475 SDFECSLCMRLFFEPVTTPCGHSFCKNCLERCLDHAPY-CPLCKESLKE 522
Score = 33.1 bits (74), Expect = 0.63
Identities = 13/36 (36%), Positives = 18/36 (50%)
Query: 70 CPICLMALREAVQTPCGHRFCKACIIKSIRDAGHKC 105
C C L E V PCGH +C+ C+ + +R C
Sbjct: 123 CLGCRGFLSEPVTVPCGHSYCRRCLRRELRARCRLC 158
>gi|20162564 tripartite motif-containing 40 [Homo sapiens]
Length = 229
Score = 47.0 bits (110), Expect = 4e-05
Identities = 30/100 (30%), Positives = 46/100 (46%), Gaps = 18/100 (18%)
Query: 70 CPICLMALREAVQTPCGHRFCKACIIKSIRDA---GHKC------PVDNEILLENQLFPD 120
CPIC +L+EAV T CGH FC+ C+ + + A G C P E+L + P+
Sbjct: 14 CPICQESLKEAVSTNCGHLFCRVCLTQHVEKASASGVFCCPLCRKPCSEEVLGTGYICPN 73
Query: 121 N------FAKREILSLMVKC---PNEGCLHKMELRHLEDH 151
+ F + L L V+C P H++ + + H
Sbjct: 74 HQKRVCRFCEESRLLLCVECLVSPEHMSHHELTIENALSH 113
Database: hs.faa
Posted date: Aug 4, 2009 4:42 PM
Number of letters in database: 18,247,518
Number of sequences in database: 37,866
Lambda K H
0.323 0.136 0.425
Gapped
Lambda K H
0.267 0.0410 0.140
Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Hits to DB: 21,177,560
Number of Sequences: 37866
Number of extensions: 979863
Number of successful extensions: 3754
Number of sequences better than 10.0: 30
Number of HSP's better than 10.0 without gapping: 220
Number of HSP's successfully gapped in prelim test: 139
Number of HSP's that attempted gapping in prelim test: 3159
Number of HSP's gapped (non-prelim): 636
length of query: 522
length of database: 18,247,518
effective HSP length: 107
effective length of query: 415
effective length of database: 14,195,856
effective search space: 5891280240
effective search space used: 5891280240
T: 11
A: 40
X1: 16 ( 7.4 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 41 (22.0 bits)
S2: 64 (29.3 bits)
Search results were obtained with NCBI BLAST and RefSeq entries.
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Guide to the Human Genome
Copyright © 2010 by Stewart Scherer. All rights reserved.