Guide to the Human Genome
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Search of human proteins with 4758754

BLASTP 2.2.11 [Jun-05-2005]


Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer, 
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), 
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs",  Nucleic Acids Res. 25:3389-3402.

Query= gi|4758754 napsin A preproprotein [Homo sapiens]
         (420 letters)

Database: hs.faa 
           37,866 sequences; 18,247,518 total letters

Searching..................................................done

                                                                 Score    E
Sequences producing significant alignments:                      (bits) Value

gi|4758754 napsin A preproprotein [Homo sapiens]                      866   0.0  
gi|4503143 cathepsin D preproprotein [Homo sapiens]                   386   e-107
gi|4503145 cathepsin E isoform a preproprotein [Homo sapiens]         334   1e-91
gi|4506475 renin preproprotein [Homo sapiens]                         298   6e-81
gi|23943854 pepsinogen 5, group I [Homo sapiens]                      287   1e-77
gi|119372302 pepsinogen 4, group I [Homo sapiens]                     286   2e-77
gi|119372298 pepsinogen 3, group I [Homo sapiens]                     286   2e-77
gi|4505757 progastricsin (pepsinogen C) [Homo sapiens]                250   1e-66
gi|23110952 cathepsin E isoform b preproprotein [Homo sapiens]        210   2e-54
gi|21040360 beta-site APP-cleaving enzyme 2 isoform C preproprot...    78   2e-14
gi|19923395 beta-site APP-cleaving enzyme 2 isoform A preproprot...    77   3e-14
gi|21040362 beta-site APP-cleaving enzyme 2 isoform B preproprot...    77   3e-14
gi|169218035 PREDICTED: similar to pepsinogen 3, group I [Homo s...    67   3e-11
gi|6912266 beta-site APP-cleaving enzyme 1 isoform A preproprote...    66   7e-11
gi|21040366 beta-site APP-cleaving enzyme 1 isoform B preproprot...    61   2e-09
gi|21040364 beta-site APP-cleaving enzyme 1 isoform C preproprot...    50   4e-06
gi|21040368 beta-site APP-cleaving enzyme 1 isoform D preproprot...    48   2e-05
gi|26986534 Rho GTPase activating protein 12 [Homo sapiens]            31   2.4  
gi|11321593 insulin-like growth factor binding protein 6 [Homo s...    29   7.0  
gi|239753040 PREDICTED: hypothetical protein XP_002345331 [Homo ...    29   7.0  
gi|239747598 PREDICTED: hypothetical protein XP_002347782 [Homo ...    29   7.0  
gi|239741463 PREDICTED: hypothetical protein XP_002342210 [Homo ...    29   7.0  
gi|22507376 G-protein coupled receptor TG1019 [Homo sapiens]           29   9.1  

>gi|4758754 napsin A preproprotein [Homo sapiens]
          Length = 420

 Score =  866 bits (2237), Expect = 0.0
 Identities = 420/420 (100%), Positives = 420/420 (100%)

Query: 1   MSPPPLLQPLLLLLPLLNVEPSGATLIRIPLHRVQPGRRILNLLRGWREPAELPKLGAPS 60
           MSPPPLLQPLLLLLPLLNVEPSGATLIRIPLHRVQPGRRILNLLRGWREPAELPKLGAPS
Sbjct: 1   MSPPPLLQPLLLLLPLLNVEPSGATLIRIPLHRVQPGRRILNLLRGWREPAELPKLGAPS 60

Query: 61  PGDKPIFVPLSNYRDVQYFGEIGLGTPPQNFTVAFDTGSSNLWVPSRRCHFFSVPCWLHH 120
           PGDKPIFVPLSNYRDVQYFGEIGLGTPPQNFTVAFDTGSSNLWVPSRRCHFFSVPCWLHH
Sbjct: 61  PGDKPIFVPLSNYRDVQYFGEIGLGTPPQNFTVAFDTGSSNLWVPSRRCHFFSVPCWLHH 120

Query: 121 RFDPKASSSFQANGTKFAIQYGTGRVDGILSEDKLTIGGIKGASVIFGEALWEPSLVFAF 180
           RFDPKASSSFQANGTKFAIQYGTGRVDGILSEDKLTIGGIKGASVIFGEALWEPSLVFAF
Sbjct: 121 RFDPKASSSFQANGTKFAIQYGTGRVDGILSEDKLTIGGIKGASVIFGEALWEPSLVFAF 180

Query: 181 AHFDGILGLGFPILSVEGVRPPMDVLVEQGLLDKPVFSFYLNRDPEEPDGGELVLGGSDP 240
           AHFDGILGLGFPILSVEGVRPPMDVLVEQGLLDKPVFSFYLNRDPEEPDGGELVLGGSDP
Sbjct: 181 AHFDGILGLGFPILSVEGVRPPMDVLVEQGLLDKPVFSFYLNRDPEEPDGGELVLGGSDP 240

Query: 241 AHYIPPLTFVPVTVPAYWQIHMERVKVGPGLTLCAKGCAAILDTGTSLITGPTEEIRALH 300
           AHYIPPLTFVPVTVPAYWQIHMERVKVGPGLTLCAKGCAAILDTGTSLITGPTEEIRALH
Sbjct: 241 AHYIPPLTFVPVTVPAYWQIHMERVKVGPGLTLCAKGCAAILDTGTSLITGPTEEIRALH 300

Query: 301 AAIGGIPLLAGEYIILCSEIPKLPAVSFLLGGVWFNLTAHDYVIQTTRNGVRLCLSGFQA 360
           AAIGGIPLLAGEYIILCSEIPKLPAVSFLLGGVWFNLTAHDYVIQTTRNGVRLCLSGFQA
Sbjct: 301 AAIGGIPLLAGEYIILCSEIPKLPAVSFLLGGVWFNLTAHDYVIQTTRNGVRLCLSGFQA 360

Query: 361 LDVPPPAGPFWILGDVFLGTYVAVFDRGDMKSSARVGLARARTRGADLGWGETAQAQFPG 420
           LDVPPPAGPFWILGDVFLGTYVAVFDRGDMKSSARVGLARARTRGADLGWGETAQAQFPG
Sbjct: 361 LDVPPPAGPFWILGDVFLGTYVAVFDRGDMKSSARVGLARARTRGADLGWGETAQAQFPG 420


>gi|4503143 cathepsin D preproprotein [Homo sapiens]
          Length = 412

 Score =  386 bits (991), Expect = e-107
 Identities = 192/413 (46%), Positives = 265/413 (64%), Gaps = 22/413 (5%)

Query: 7   LQPLLLL-LPLLNVEPSGATLIRIPLHRVQPGRRILNLLRGWRE------PAELPKLGAP 59
           +QP  LL L L  +    + L+RIPLH+    RR ++ + G  E      P        P
Sbjct: 1   MQPSSLLPLALCLLAAPASALVRIPLHKFTSIRRTMSEVGGSVEDLIAKGPVSKYSQAVP 60

Query: 60  SPGDKPIFVPLSNYRDVQYFGEIGLGTPPQNFTVAFDTGSSNLWVPSRRCHFFSVPCWLH 119
           +  + PI   L NY D QY+GEIG+GTPPQ FTV FDTGSSNLWVPS  C    + CW+H
Sbjct: 61  AVTEGPIPEVLKNYMDAQYYGEIGIGTPPQCFTVVFDTGSSNLWVPSIHCKLLDIACWIH 120

Query: 120 HRFDPKASSSFQANGTKFAIQYGTGRVDGILSEDKLTI-----------GGIKGASVIFG 168
           H+++   SS++  NGT F I YG+G + G LS+D +++           GG+K    +FG
Sbjct: 121 HKYNSDKSSTYVKNGTSFDIHYGSGSLSGYLSQDTVSVPCQSASSASALGGVKVERQVFG 180

Query: 169 EALWEPSLVFAFAHFDGILGLGFPILSVEGVRPPMDVLVEQGLLDKPVFSFYLNRDPEEP 228
           EA  +P + F  A FDGILG+ +P +SV  V P  D L++Q L+D+ +FSFYL+RDP+  
Sbjct: 181 EATKQPGITFIAAKFDGILGMAYPRISVNNVLPVFDNLMQQKLVDQNIFSFYLSRDPDAQ 240

Query: 229 DGGELVLGGSDPAHYIPPLTFVPVTVPAYWQIHMERVKVGPGLTLCAKGCAAILDTGTSL 288
            GGEL+LGG+D  +Y   L+++ VT  AYWQ+H+++V+V  GLTLC +GC AI+DTGTSL
Sbjct: 241 PGGELMLGGTDSKYYKGSLSYLNVTRKAYWQVHLDQVEVASGLTLCKEGCEAIVDTGTSL 300

Query: 289 ITGPTEEIRALHAAIGGIPLLAGEYIILCSEIPKLPAVSFLLGGVWFNLTAHDYVIQTTR 348
           + GP +E+R L  AIG +PL+ GEY+I C ++  LPA++  LGG  + L+  DY ++ ++
Sbjct: 301 MVGPVDEVRELQKAIGAVPLIQGEYMIPCEKVSTLPAITLKLGGKGYKLSPEDYTLKVSQ 360

Query: 349 NGVRLCLSGFQALDVPPPAGPFWILGDVFLGTYVAVFDRGDMKSSARVGLARA 401
            G  LCLSGF  +D+PPP+GP WILGDVF+G Y  VFDR     + RVG A A
Sbjct: 361 AGKTLCLSGFMGMDIPPPSGPLWILGDVFIGRYYTVFDR----DNNRVGFAEA 409


>gi|4503145 cathepsin E isoform a preproprotein [Homo sapiens]
          Length = 396

 Score =  334 bits (856), Expect = 1e-91
 Identities = 179/397 (45%), Positives = 249/397 (62%), Gaps = 12/397 (3%)

Query: 10  LLLLLPLLNVEPSGATLIRIPLHRVQPGRRILN----LLRGWREP-AELPKLGAPSPGDK 64
           LLLLL LL +  +  +L R+PL R    ++ L     L   W+    ++ +       D+
Sbjct: 5   LLLLLVLLELGEAQGSLHRVPLRRHPSLKKKLRARSQLSEFWKSHNLDMIQFTESCSMDQ 64

Query: 65  PIFVPLSNYRDVQYFGEIGLGTPPQNFTVAFDTGSSNLWVPSRRCHFFSVPCWLHHRFDP 124
               PL NY D++YFG I +G+PPQNFTV FDTGSSNLWVPS  C   S  C  H RF P
Sbjct: 65  SAKEPLINYLDMEYFGTISIGSPPQNFTVIFDTGSSNLWVPSVYCT--SPACKTHSRFQP 122

Query: 125 KASSSFQANGTKFAIQYGTGRVDGILSEDKLTIGGIKGASVIFGEALWEPSLVFAFAHFD 184
             SS++   G  F+IQYGTG + GI+  D++++ G+      FGE++ EP   F  A FD
Sbjct: 123 SQSSTYSQPGQSFSIQYGTGSLSGIIGADQVSVEGLTVVGQQFGESVTEPGQTFVDAEFD 182

Query: 185 GILGLGFPILSVEGVRPPMDVLVEQGLLDKPVFSFYLNRDPEEPDGGELVLGGSDPAHYI 244
           GILGLG+P L+V GV P  D ++ Q L+D P+FS Y++ +PE   G EL+ GG D +H+ 
Sbjct: 183 GILGLGYPSLAVGGVTPVFDNMMAQNLVDLPMFSVYMSSNPEGGAGSELIFGGYDHSHFS 242

Query: 245 PPLTFVPVTVPAYWQIHMERVKVGPGLTLCAKGCAAILDTGTSLITGPTEEIRALHAAIG 304
             L +VPVT  AYWQI ++ ++VG  +  C++GC AI+DTGTSLITGP+++I+ L  AIG
Sbjct: 243 GSLNWVPVTKQAYWQIALDNIQVGGTVMFCSEGCQAIVDTGTSLITGPSDKIKQLQNAIG 302

Query: 305 GIPLLAGEYIILCSEIPKLPAVSFLLGGVWFNLTAHDYVIQTTRNGVRLCLSGFQALDVP 364
             P + GEY + C+ +  +P V+F + GV + L+   Y +    +G++ C SGFQ LD+ 
Sbjct: 303 AAP-VDGEYAVECANLNVMPDVTFTINGVPYTLSPTAYTLLDFVDGMQFCSSGFQGLDIH 361

Query: 365 PPAGPFWILGDVFLGTYVAVFDRGDMKSSARVGLARA 401
           PPAGP WILGDVF+  + +VFDRG    + RVGLA A
Sbjct: 362 PPAGPLWILGDVFIRQFYSVFDRG----NNRVGLAPA 394


>gi|4506475 renin preproprotein [Homo sapiens]
          Length = 406

 Score =  298 bits (763), Expect = 6e-81
 Identities = 157/358 (43%), Positives = 211/358 (58%), Gaps = 13/358 (3%)

Query: 47  WREPAELPKLGAPSPGDKPIFVPLSNYRDVQYFGEIGLGTPPQNFTVAFDTGSSNLWVPS 106
           W +P +   LG  +       V L+NY D QY+GEIG+GTPPQ F V FDTGSSN+WVPS
Sbjct: 60  WSQPMKRLTLGNTTSS-----VILTNYMDTQYYGEIGIGTPPQTFKVVFDTGSSNVWVPS 114

Query: 107 RRCHFFSVPCWLHHRFDPKASSSFQANGTKFAIQYGTGRVDGILSEDKLTIGGIKGASVI 166
            +C      C  H  FD   SSS++ NGT+  ++Y TG V G LS+D +T+GGI   + +
Sbjct: 115 SKCSRLYTACVYHKLFDASDSSSYKHNGTELTLRYSTGTVSGFLSQDIITVGGIT-VTQM 173

Query: 167 FGEALWEPSLVFAFAHFDGILGLGFPILSVEGVRPPMDVLVEQGLLDKPVFSFYLNRDPE 226
           FGE    P+L F  A FDG++G+GF   ++  V P  D ++ QG+L + VFSFY NRD E
Sbjct: 174 FGEVTEMPALPFMLAEFDGVVGMGFIEQAIGRVTPIFDNIISQGVLKEDVFSFYYNRDSE 233

Query: 227 EPD--GGELVLGGSDPAHYIPPLTFVPVTVPAYWQIHMERVKVGPGLTLCAKGCAAILDT 284
                GG++VLGGSDP HY     ++ +     WQI M+ V VG    LC  GC A++DT
Sbjct: 234 NSQSLGGQIVLGGSDPQHYEGNFHYINLIKTGVWQIQMKGVSVGSSTLLCEDGCLALVDT 293

Query: 285 GTSLITGPTEEIRALHAAIGGIPLLAGEYIILCSEIPKLPAVSFLLGGVWFNLTAHDYVI 344
           G S I+G T  I  L  A+G    L  +Y++ C+E P LP +SF LGG  + LT+ DYV 
Sbjct: 294 GASYISGSTSSIEKLMEALGAKKRLF-DYVVKCNEGPTLPDISFHLGGKEYTLTSADYVF 352

Query: 345 QTTRNGVRLCLSGFQALDVPPPAGPFWILGDVFLGTYVAVFDRGDMKSSARVGLARAR 402
           Q + +  +LC     A+D+PPP GP W LG  F+  +   FDR     + R+G A AR
Sbjct: 353 QESYSSKKLCTLAIHAMDIPPPTGPTWALGATFIRKFYTEFDR----RNNRIGFALAR 406


>gi|23943854 pepsinogen 5, group I [Homo sapiens]
          Length = 388

 Score =  287 bits (735), Expect = 1e-77
 Identities = 165/399 (41%), Positives = 237/399 (59%), Gaps = 27/399 (6%)

Query: 11  LLLLPLLNVEPSGATLIRIPLHRVQPGRRILN---LLRGWREPAEL-------PKLGAPS 60
           LLLL L+ +  S   + ++PL R +  RR L+   LL+ + +   L       P+  AP+
Sbjct: 4   LLLLGLVAL--SECIMYKVPLIRKKSLRRTLSERGLLKDFLKKHNLNPARKYFPQWEAPT 61

Query: 61  PGDKPIFVPLSNYRDVQYFGEIGLGTPPQNFTVAFDTGSSNLWVPSRRCHFFSVPCWLHH 120
             D+    PL NY D++YFG IG+GTP Q+FTV FDTGSSNLWVPS  C   S+ C  H+
Sbjct: 62  LVDEQ---PLENYLDMEYFGTIGIGTPAQDFTVVFDTGSSNLWVPSVYCS--SLACTNHN 116

Query: 121 RFDPKASSSFQANGTKFAIQYGTGRVDGILSEDKLTIGGIKGASVIFGEALWEPSLVFAF 180
           RF+P+ SS++Q+     +I YGTG + GIL  D + +GGI   + IFG +  EP     +
Sbjct: 117 RFNPEDSSTYQSTSETVSITYGTGSMTGILGYDTVQVGGISDTNQIFGLSETEPGSFLYY 176

Query: 181 AHFDGILGLGFPILSVEGVRPPMDVLVEQGLLDKPVFSFYLNRDPEEPDGGELVLGGSDP 240
           A FDGILGL +P +S  G  P  D +  QGL+ + +FS YL+ D  +  G  ++ GG D 
Sbjct: 177 APFDGILGLAYPSISSSGATPVFDNIWNQGLVSQDLFSVYLSAD--DKSGSVVIFGGIDS 234

Query: 241 AHYIPPLTFVPVTVPAYWQIHMERVKVGPGLTLCAKGCAAILDTGTSLITGPTEEIRALH 300
           ++Y   L +VPVTV  YWQI ++ + +      CA+GC AI+DTGTSL+TGPT  I  + 
Sbjct: 235 SYYTGSLNWVPVTVEGYWQITVDSITMNGETIACAEGCQAIVDTGTSLLTGPTSPIANIQ 294

Query: 301 AAIGGIPLLAGEYIILCSEIPKLPAVSFLLGGVWFNLTAHDYVIQTTRNGVRLCLSGFQA 360
           + IG      G+ ++ CS I  LP + F + GV + +    Y++Q+  +    C+SGFQ 
Sbjct: 295 SDIGASENSDGDMVVSCSAISSLPDIVFTINGVQYPVPPSAYILQSEGS----CISGFQG 350

Query: 361 LDVPPPAGPFWILGDVFLGTYVAVFDRGDMKSSARVGLA 399
           ++VP  +G  WILGDVF+  Y  VFDR    ++ +VGLA
Sbjct: 351 MNVPTESGELWILGDVFIRQYFTVFDR----ANNQVGLA 385


>gi|119372302 pepsinogen 4, group I [Homo sapiens]
          Length = 388

 Score =  286 bits (732), Expect = 2e-77
 Identities = 164/399 (41%), Positives = 237/399 (59%), Gaps = 27/399 (6%)

Query: 11  LLLLPLLNVEPSGATLIRIPLHRVQPGRRILN---LLRGWREPAEL-------PKLGAPS 60
           LLLL L+ +  S   + ++PL R +  RR L+   LL+ + +   L       P+  AP+
Sbjct: 4   LLLLGLVAL--SECIMYKVPLIRKKSLRRTLSERGLLKDFLKKHNLNPARKYFPQWEAPT 61

Query: 61  PGDKPIFVPLSNYRDVQYFGEIGLGTPPQNFTVAFDTGSSNLWVPSRRCHFFSVPCWLHH 120
             D+    PL NY D++YFG IG+GTP Q+FTV FDTGSSNLWVPS  C   S+ C  H+
Sbjct: 62  LVDEQ---PLENYLDMEYFGTIGIGTPAQDFTVVFDTGSSNLWVPSVYCS--SLACTNHN 116

Query: 121 RFDPKASSSFQANGTKFAIQYGTGRVDGILSEDKLTIGGIKGASVIFGEALWEPSLVFAF 180
           RF+P+ SS++Q+     +I YGTG + GIL  D + +GGI   + IFG +  EP     +
Sbjct: 117 RFNPEDSSTYQSTSETVSITYGTGSMTGILGYDTVQVGGISDTNQIFGLSETEPGSFLYY 176

Query: 181 AHFDGILGLGFPILSVEGVRPPMDVLVEQGLLDKPVFSFYLNRDPEEPDGGELVLGGSDP 240
           A FDGILGL +P +S  G  P  D +  QGL+ + +FS YL+ D +   G  ++ GG D 
Sbjct: 177 APFDGILGLAYPSISSSGATPVFDNIWNQGLVSQDLFSVYLSADDQS--GSVVIFGGIDS 234

Query: 241 AHYIPPLTFVPVTVPAYWQIHMERVKVGPGLTLCAKGCAAILDTGTSLITGPTEEIRALH 300
           ++Y   L +VPVTV  YWQI ++ + +      CA+GC AI+DTGTSL+TGPT  I  + 
Sbjct: 235 SYYTGSLNWVPVTVEGYWQITVDSITMNGEAIACAEGCQAIVDTGTSLLTGPTSPIANIQ 294

Query: 301 AAIGGIPLLAGEYIILCSEIPKLPAVSFLLGGVWFNLTAHDYVIQTTRNGVRLCLSGFQA 360
           + IG      G+ ++ CS I  LP + F + GV + +    Y++Q+  +    C+SGFQ 
Sbjct: 295 SDIGASENSDGDMVVSCSAISSLPDIVFTINGVQYPVPPSAYILQSEGS----CISGFQG 350

Query: 361 LDVPPPAGPFWILGDVFLGTYVAVFDRGDMKSSARVGLA 399
           +++P  +G  WILGDVF+  Y  VFDR    ++ +VGLA
Sbjct: 351 MNLPTESGELWILGDVFIRQYFTVFDR----ANNQVGLA 385


>gi|119372298 pepsinogen 3, group I [Homo sapiens]
          Length = 388

 Score =  286 bits (732), Expect = 2e-77
 Identities = 164/399 (41%), Positives = 237/399 (59%), Gaps = 27/399 (6%)

Query: 11  LLLLPLLNVEPSGATLIRIPLHRVQPGRRILN---LLRGWREPAEL-------PKLGAPS 60
           LLLL L+ +  S   + ++PL R +  RR L+   LL+ + +   L       P+  AP+
Sbjct: 4   LLLLGLVAL--SECIMYKVPLIRKKSLRRTLSERGLLKDFLKKHNLNPARKYFPQWKAPT 61

Query: 61  PGDKPIFVPLSNYRDVQYFGEIGLGTPPQNFTVAFDTGSSNLWVPSRRCHFFSVPCWLHH 120
             D+    PL NY D++YFG IG+GTP Q+FTV FDTGSSNLWVPS  C   S+ C  H+
Sbjct: 62  LVDEQ---PLENYLDMEYFGTIGIGTPAQDFTVVFDTGSSNLWVPSVYCS--SLACTNHN 116

Query: 121 RFDPKASSSFQANGTKFAIQYGTGRVDGILSEDKLTIGGIKGASVIFGEALWEPSLVFAF 180
           RF+P+ SS++Q+     +I YGTG + GIL  D + +GGI   + IFG +  EP     +
Sbjct: 117 RFNPEDSSTYQSTSETVSITYGTGSMTGILGYDTVQVGGISDTNQIFGLSETEPGSFLYY 176

Query: 181 AHFDGILGLGFPILSVEGVRPPMDVLVEQGLLDKPVFSFYLNRDPEEPDGGELVLGGSDP 240
           A FDGILGL +P +S  G  P  D +  QGL+ + +FS YL+ D +   G  ++ GG D 
Sbjct: 177 APFDGILGLAYPSISSSGATPVFDNIWNQGLVSQDLFSVYLSADDQS--GSVVIFGGIDS 234

Query: 241 AHYIPPLTFVPVTVPAYWQIHMERVKVGPGLTLCAKGCAAILDTGTSLITGPTEEIRALH 300
           ++Y   L +VPVTV  YWQI ++ + +      CA+GC AI+DTGTSL+TGPT  I  + 
Sbjct: 235 SYYTGSLNWVPVTVEGYWQITVDSITMNGEAIACAEGCQAIVDTGTSLLTGPTSPIANIQ 294

Query: 301 AAIGGIPLLAGEYIILCSEIPKLPAVSFLLGGVWFNLTAHDYVIQTTRNGVRLCLSGFQA 360
           + IG      G+ ++ CS I  LP + F + GV + +    Y++Q+  +    C+SGFQ 
Sbjct: 295 SDIGASENSDGDMVVSCSAISSLPDIVFTINGVQYPVPPSAYILQSEGS----CISGFQG 350

Query: 361 LDVPPPAGPFWILGDVFLGTYVAVFDRGDMKSSARVGLA 399
           +++P  +G  WILGDVF+  Y  VFDR    ++ +VGLA
Sbjct: 351 MNLPTESGELWILGDVFIRQYFTVFDR----ANNQVGLA 385


>gi|4505757 progastricsin (pepsinogen C) [Homo sapiens]
          Length = 388

 Score =  250 bits (639), Expect = 1e-66
 Identities = 143/342 (41%), Positives = 198/342 (57%), Gaps = 13/342 (3%)

Query: 62  GDKPIFVPLSNYRDVQYFGEIGLGTPPQNFTVAFDTGSSNLWVPSRRCHFFSVPCWLHHR 121
           GD  +      Y D  YFGEI +GTPPQNF V FDTGSSNLWVPS  C   S  C  H R
Sbjct: 57  GDLSVTYEPMAYMDAAYFGEISIGTPPQNFLVLFDTGSSNLWVPSVYCQ--SQACTSHSR 114

Query: 122 FDPKASSSFQANGTKFAIQYGTGRVDGILSEDKLTIGGIKGASVIFGEALWEPSLVFAFA 181
           F+P  SS++  NG  F++QYG+G + G    D LT+  I+  +  FG +  EP   F +A
Sbjct: 115 FNPSESSTYSTNGQTFSLQYGSGSLTGFFGYDTLTVQSIQVPNQEFGLSENEPGTNFVYA 174

Query: 182 HFDGILGLGFPILSVEGVRPPMDVLVEQGLLDKPVFSFYLNRDPEEPDGGELVLGGSDPA 241
            FDGI+GL +P LSV+     M  +V++G L  PVFS YL+ + +   GG +V GG D +
Sbjct: 175 QFDGIMGLAYPALSVDEATTAMQGMVQEGALTSPVFSVYLS-NQQGSSGGAVVFGGVDSS 233

Query: 242 HYIPPLTFVPVTVPAYWQIHMERVKVGPGLT-LCAKGCAAILDTGTSLITGPTEEIRALH 300
            Y   + + PVT   YWQI +E   +G   +  C++GC AI+DTGTSL+T P + + AL 
Sbjct: 234 LYTGQIYWAPVTQELYWQIGIEEFLIGGQASGWCSEGCQAIVDTGTSLLTVPQQYMSALL 293

Query: 301 AAIGGIPLLAGEYIILCSEIPKLPAVSFLLGGVWFNLTAHDYVIQTTRNGVRLCLSGFQA 360
            A G      G++++ C+ I  LP+++F++ GV F L    Y++  + NG   C  G + 
Sbjct: 294 QATGAQEDEYGQFLVNCNSIQNLPSLTFIINGVEFPLPPSSYIL--SNNG--YCTVGVEP 349

Query: 361 LDVPPPAG-PFWILGDVFLGTYVAVFDRGDMKSSARVGLARA 401
             +    G P WILGDVFL +Y +V+D G    + RVG A A
Sbjct: 350 TYLSSQNGQPLWILGDVFLRSYYSVYDLG----NNRVGFATA 387


>gi|23110952 cathepsin E isoform b preproprotein [Homo sapiens]
          Length = 363

 Score =  210 bits (535), Expect = 2e-54
 Identities = 118/271 (43%), Positives = 161/271 (59%), Gaps = 8/271 (2%)

Query: 10  LLLLLPLLNVEPSGATLIRIPLHRVQPGRRILN----LLRGWREP-AELPKLGAPSPGDK 64
           LLLLL LL +  +  +L R+PL R    ++ L     L   W+    ++ +       D+
Sbjct: 5   LLLLLVLLELGEAQGSLHRVPLRRHPSLKKKLRARSQLSEFWKSHNLDMIQFTESCSMDQ 64

Query: 65  PIFVPLSNYRDVQYFGEIGLGTPPQNFTVAFDTGSSNLWVPSRRCHFFSVPCWLHHRFDP 124
               PL NY D++YFG I +G+PPQNFTV FDTGSSNLWVPS  C   S  C  H RF P
Sbjct: 65  SAKEPLINYLDMEYFGTISIGSPPQNFTVIFDTGSSNLWVPSVYCT--SPACKTHSRFQP 122

Query: 125 KASSSFQANGTKFAIQYGTGRVDGILSEDKLTIGGIKGASVIFGEALWEPSLVFAFAHFD 184
             SS++   G  F+IQYGTG + GI+  D++++ G+      FGE++ EP   F  A FD
Sbjct: 123 SQSSTYSQPGQSFSIQYGTGSLSGIIGADQVSVEGLTVVGQQFGESVTEPGQTFVDAEFD 182

Query: 185 GILGLGFPILSVEGVRPPMDVLVEQGLLDKPVFSFYLNRDPEEPDGGELVLGGSDPAHYI 244
           GILGLG+P L+V GV P  D ++ Q L+D P+FS Y++ +PE   G EL+ GG D +H+ 
Sbjct: 183 GILGLGYPSLAVGGVTPVFDNMMAQNLVDLPMFSVYMSSNPEGGAGSELIFGGYDHSHFS 242

Query: 245 PPLTFVPVTVPAYWQIHMERVKVG-PGLTLC 274
             L +VPVT  AYWQI ++ +    P LT C
Sbjct: 243 GSLNWVPVTKQAYWQIALDNMLWSVPTLTSC 273


>gi|21040360 beta-site APP-cleaving enzyme 2 isoform C preproprotein
           [Homo sapiens]
          Length = 468

 Score = 77.8 bits (190), Expect = 2e-14
 Identities = 75/251 (29%), Positives = 121/251 (48%), Gaps = 32/251 (12%)

Query: 78  YFGEIGLGTPPQNFTVAFDTGSSNLWVPSRRCHFFSVPCWLHHRFDPKASSSFQANGTKF 137
           Y+ E+ +GTPPQ   +  DTGSSN  V        +   ++   FD + SS++++ G   
Sbjct: 92  YYLEMLIGTPPQKLQILVDTGSSNFAVAG------TPHSYIDTYFDTERSSTYRSKGFDV 145

Query: 138 AIQYGTGRVDGILSEDKLTIGGIKGASVIFGEALWEPSLVFAFAHF-------DGILGLG 190
            ++Y  G   G + ED +TI   KG +  F   L   + +F   +F       +GILGL 
Sbjct: 146 TVKYTQGSWTGFVGEDLVTIP--KGFNTSF---LVNIATIFESENFFLPGIKWNGILGLA 200

Query: 191 FPILSV--EGVRPPMDVLVEQGLLDKPVFSFY-----LNRDPEEPDGGELVLGGSDPAHY 243
           +  L+     +    D LV Q  +   VFS       L       +GG LVLGG +P+ Y
Sbjct: 201 YATLAKPSSSLETFFDSLVTQANIPN-VFSMQMCGAGLPVAGSGTNGGSLVLGGIEPSLY 259

Query: 244 IPPLTFVPVTVPAYWQIHMERVKVGPGLTL---CAKGCA--AILDTGTSLITGPTEEIRA 298
              + + P+    Y+QI + ++++G G +L   C +  A  AI+D+GT+L+  P +   A
Sbjct: 260 KGDIWYTPIKEEWYYQIEILKLEIG-GQSLNLDCREYNADKAIVDSGTTLLRLPQKVFDA 318

Query: 299 LHAAIGGIPLL 309
           +  A+    LL
Sbjct: 319 VVEAVARASLL 329


>gi|19923395 beta-site APP-cleaving enzyme 2 isoform A preproprotein
           [Homo sapiens]
          Length = 518

 Score = 77.0 bits (188), Expect = 3e-14
 Identities = 74/251 (29%), Positives = 121/251 (48%), Gaps = 32/251 (12%)

Query: 78  YFGEIGLGTPPQNFTVAFDTGSSNLWVPSRRCHFFSVPCWLHHRFDPKASSSFQANGTKF 137
           Y+ E+ +GTPPQ   +  DTGSSN  V        +   ++   FD + SS++++ G   
Sbjct: 92  YYLEMLIGTPPQKLQILVDTGSSNFAVAG------TPHSYIDTYFDTERSSTYRSKGFDV 145

Query: 138 AIQYGTGRVDGILSEDKLTIGGIKGASVIFGEALWEPSLVFAFAHF-------DGILGLG 190
            ++Y  G   G + ED +TI   KG +  F   L   + +F   +F       +GILGL 
Sbjct: 146 TVKYTQGSWTGFVGEDLVTIP--KGFNTSF---LVNIATIFESENFFLPGIKWNGILGLA 200

Query: 191 FPILSV--EGVRPPMDVLVEQGLLDKPVFSFY-----LNRDPEEPDGGELVLGGSDPAHY 243
           +  L+     +    D LV Q  +   VFS       L       +GG LVLGG +P+ Y
Sbjct: 201 YATLAKPSSSLETFFDSLVTQANIPN-VFSMQMCGAGLPVAGSGTNGGSLVLGGIEPSLY 259

Query: 244 IPPLTFVPVTVPAYWQIHMERVKVGPGLTL---CAKGCA--AILDTGTSLITGPTEEIRA 298
              + + P+    Y+QI + ++++G G +L   C +  A  AI+D+GT+L+  P +   A
Sbjct: 260 KGDIWYTPIKEEWYYQIEILKLEIG-GQSLNLDCREYNADKAIVDSGTTLLRLPQKVFDA 318

Query: 299 LHAAIGGIPLL 309
           +  A+    L+
Sbjct: 319 VVEAVARASLI 329


>gi|21040362 beta-site APP-cleaving enzyme 2 isoform B preproprotein
           [Homo sapiens]
          Length = 396

 Score = 77.0 bits (188), Expect = 3e-14
 Identities = 74/251 (29%), Positives = 121/251 (48%), Gaps = 32/251 (12%)

Query: 78  YFGEIGLGTPPQNFTVAFDTGSSNLWVPSRRCHFFSVPCWLHHRFDPKASSSFQANGTKF 137
           Y+ E+ +GTPPQ   +  DTGSSN  V        +   ++   FD + SS++++ G   
Sbjct: 92  YYLEMLIGTPPQKLQILVDTGSSNFAVAG------TPHSYIDTYFDTERSSTYRSKGFDV 145

Query: 138 AIQYGTGRVDGILSEDKLTIGGIKGASVIFGEALWEPSLVFAFAHF-------DGILGLG 190
            ++Y  G   G + ED +TI   KG +  F   L   + +F   +F       +GILGL 
Sbjct: 146 TVKYTQGSWTGFVGEDLVTIP--KGFNTSF---LVNIATIFESENFFLPGIKWNGILGLA 200

Query: 191 FPILSV--EGVRPPMDVLVEQGLLDKPVFSFY-----LNRDPEEPDGGELVLGGSDPAHY 243
           +  L+     +    D LV Q  +   VFS       L       +GG LVLGG +P+ Y
Sbjct: 201 YATLAKPSSSLETFFDSLVTQANIPN-VFSMQMCGAGLPVAGSGTNGGSLVLGGIEPSLY 259

Query: 244 IPPLTFVPVTVPAYWQIHMERVKVGPGLTL---CAKGCA--AILDTGTSLITGPTEEIRA 298
              + + P+    Y+QI + ++++G G +L   C +  A  AI+D+GT+L+  P +   A
Sbjct: 260 KGDIWYTPIKEEWYYQIEILKLEIG-GQSLNLDCREYNADKAIVDSGTTLLRLPQKVFDA 318

Query: 299 LHAAIGGIPLL 309
           +  A+    L+
Sbjct: 319 VVEAVARASLI 329


>gi|169218035 PREDICTED: similar to pepsinogen 3, group I [Homo
           sapiens]
          Length = 87

 Score = 67.0 bits (162), Expect = 3e-11
 Identities = 31/75 (41%), Positives = 45/75 (60%)

Query: 274 CAKGCAAILDTGTSLITGPTEEIRALHAAIGGIPLLAGEYIILCSEIPKLPAVSFLLGGV 333
           CA+GC AI+DTGTSL+TGPT  I  + + IG      G+ ++ CS I  LP + F + GV
Sbjct: 8   CAEGCQAIVDTGTSLLTGPTSPIANIQSDIGASENSDGDMVVSCSAISSLPDIVFTINGV 67

Query: 334 WFNLTAHDYVIQTTR 348
            + +    Y++Q  R
Sbjct: 68  QYPVPPSAYILQVRR 82


>gi|6912266 beta-site APP-cleaving enzyme 1 isoform A preproprotein
           [Homo sapiens]
          Length = 501

 Score = 65.9 bits (159), Expect = 7e-11
 Identities = 87/312 (27%), Positives = 142/312 (45%), Gaps = 35/312 (11%)

Query: 9   PLLLLLPLLNVEPSGATL--IRIPLHRVQPGRRILNLLRGWREPAELPKLGAPSPGDKPI 66
           P LLL     V P+  T   IR+PL     G  +   LR  RE  E P+     PG +  
Sbjct: 6   PWLLLWMGAGVLPAHGTQHGIRLPLRSGLGGAPLG--LRLPRETDEEPE----EPGRRGS 59

Query: 67  FVPL-SNYRDVQ---YFGEIGLGTPPQNFTVAFDTGSSNLWVPSRRCHFFSVPCWLHHRF 122
           FV +  N R      Y+ E+ +G+PPQ   +  DTGSSN  V +    F      LH  +
Sbjct: 60  FVEMVDNLRGKSGQGYYVEMTVGSPPQTLNILVDTGSSNFAVGAAPHPF------LHRYY 113

Query: 123 DPKASSSFQANGTKFAIQYGTGRVDGILSEDKLTIGGIKGASVIFGEALWEPSLVFAF-- 180
             + SS+++       + Y  G+ +G L  D ++I      +V    A    S  F    
Sbjct: 114 QRQLSSTYRDLRKGVYVPYTQGKWEGELGTDLVSIPHGPNVTVRANIAAITESDKFFING 173

Query: 181 AHFDGILGLGFPILS--VEGVRPPMDVLVEQGLLDKPVFS-------FYLNRDPEEPD-G 230
           ++++GILGL +  ++   + + P  D LV+Q  +   +FS       F LN+       G
Sbjct: 174 SNWEGILGLAYAEIARPDDSLEPFFDSLVKQTHVPN-LFSLQLCGAGFPLNQSEVLASVG 232

Query: 231 GELVLGGSDPAHYIPPLTFVPVTVPAYWQIHMERVKV-GPGLTLCAKGC---AAILDTGT 286
           G +++GG D + Y   L + P+    Y+++ + RV++ G  L +  K      +I+D+GT
Sbjct: 233 GSMIIGGIDHSLYTGSLWYTPIRREWYYEVIIVRVEINGQDLKMDCKEYNYDKSIVDSGT 292

Query: 287 SLITGPTEEIRA 298
           + +  P +   A
Sbjct: 293 TNLRLPKKVFEA 304


>gi|21040366 beta-site APP-cleaving enzyme 1 isoform B preproprotein
           [Homo sapiens]
          Length = 476

 Score = 60.8 bits (146), Expect = 2e-09
 Identities = 81/313 (25%), Positives = 127/313 (40%), Gaps = 62/313 (19%)

Query: 9   PLLLLLPLLNVEPSGATL--IRIPLHRVQPGRRILNLLRGWREPAELPKLGAPSPGDKPI 66
           P LLL     V P+  T   IR+PL     G  +   LR  RE  E P+     PG +  
Sbjct: 6   PWLLLWMGAGVLPAHGTQHGIRLPLRSGLGGAPLG--LRLPRETDEEPE----EPGRRGS 59

Query: 67  FVPL-SNYRDVQ---YFGEIGLGTPPQNFTVAFDTGSSNLWVPSRRCHFFSVPCWLHHRF 122
           FV +  N R      Y+ E+ +G+PPQ   +  DTGSSN  V +    F      LH  +
Sbjct: 60  FVEMVDNLRGKSGQGYYVEMTVGSPPQTLNILVDTGSSNFAVGAAPHPF------LHRYY 113

Query: 123 DPKASSSFQANGTKFAIQYGTGRVDGILSEDKLTIGGIKGASV-------------IFGE 169
             + SS+++       + Y  G+ +G L  D ++I      +V                 
Sbjct: 114 QRQLSSTYRDLRKGVYVPYTQGKWEGELGTDLVSIPHGPNVTVRANIAAITESDKFFING 173

Query: 170 ALWEPSLVFAFAHFDGILGLGFPILSVEGVRPPMDVLVEQGLLDKPVFSFYLNRDPEEPD 229
           + WE  L  A+A    + G GFP+   E       VL                       
Sbjct: 174 SNWEGILGLAYAEIARLCGAGFPLNQSE-------VLASV-------------------- 206

Query: 230 GGELVLGGSDPAHYIPPLTFVPVTVPAYWQIHMERVKV-GPGLTLCAKGC---AAILDTG 285
           GG +++GG D + Y   L + P+    Y+++ + RV++ G  L +  K      +I+D+G
Sbjct: 207 GGSMIIGGIDHSLYTGSLWYTPIRREWYYEVIIVRVEINGQDLKMDCKEYNYDKSIVDSG 266

Query: 286 TSLITGPTEEIRA 298
           T+ +  P +   A
Sbjct: 267 TTNLRLPKKVFEA 279


>gi|21040364 beta-site APP-cleaving enzyme 1 isoform C preproprotein
           [Homo sapiens]
          Length = 457

 Score = 50.1 bits (118), Expect = 4e-06
 Identities = 83/308 (26%), Positives = 126/308 (40%), Gaps = 71/308 (23%)

Query: 9   PLLLLLPLLNVEPSGATL--IRIPLHRVQPGRRILNLLRGWREPAELPKLGAPSPGDKPI 66
           P LLL     V P+  T   IR+PL     G  +   LR  RE  E P+     PG +  
Sbjct: 6   PWLLLWMGAGVLPAHGTQHGIRLPLRSGLGGAPLG--LRLPRETDEEPE----EPGRRGS 59

Query: 67  FVPL-SNYRDVQ---YFGEIGLGTPPQNFTVAFDTGSSNLWVPSRRCHFFSVPCWLHHRF 122
           FV +  N R      Y+ E+ +G+PPQ   +  DTGSSN  V +    F      LH  +
Sbjct: 60  FVEMVDNLRGKSGQGYYVEMTVGSPPQTLNILVDTGSSNFAVGAAPHPF------LHRYY 113

Query: 123 DPKASSSFQANGTKFAIQYGTGRVDGILSEDKLTIGGIKGASVIFGEALWEPSLVFAFAH 182
             + SS+++                             KG  V + +  WE         
Sbjct: 114 QRQLSSTYRDLR--------------------------KGVYVPYTQGKWE--------- 138

Query: 183 FDGILGLGFPILSVEGVRPPMDVLVEQGLLDKPVFS-------FYLNRDPEEPD-GGELV 234
             G LG   P  S+E   P  D LV+Q  +   +FS       F LN+       GG ++
Sbjct: 139 --GELGTDLPDDSLE---PFFDSLVKQTHVPN-LFSLQLCGAGFPLNQSEVLASVGGSMI 192

Query: 235 LGGSDPAHYIPPLTFVPVTVPAYWQIHMERVKV-GPGLTLCAKGC---AAILDTGTSLIT 290
           +GG D + Y   L + P+    Y+++ + RV++ G  L +  K      +I+D+GT+ + 
Sbjct: 193 IGGIDHSLYTGSLWYTPIRREWYYEVIIVRVEINGQDLKMDCKEYNYDKSIVDSGTTNLR 252

Query: 291 GPTEEIRA 298
            P +   A
Sbjct: 253 LPKKVFEA 260


>gi|21040368 beta-site APP-cleaving enzyme 1 isoform D preproprotein
           [Homo sapiens]
          Length = 432

 Score = 47.8 bits (112), Expect = 2e-05
 Identities = 75/300 (25%), Positives = 115/300 (38%), Gaps = 80/300 (26%)

Query: 9   PLLLLLPLLNVEPSGATL--IRIPLHRVQPGRRILNLLRGWREPAELPKLGAPSPGDKPI 66
           P LLL     V P+  T   IR+PL     G  +   LR  RE  E P+     PG +  
Sbjct: 6   PWLLLWMGAGVLPAHGTQHGIRLPLRSGLGGAPLG--LRLPRETDEEPE----EPGRRGS 59

Query: 67  FVPL-SNYRDVQ---YFGEIGLGTPPQNFTVAFDTGSSNLWVPSRRCHFFSVPCWLHHRF 122
           FV +  N R      Y+ E+ +G+PPQ   +  DTGSSN  V +    F      LH  +
Sbjct: 60  FVEMVDNLRGKSGQGYYVEMTVGSPPQTLNILVDTGSSNFAVGAAPHPF------LHRYY 113

Query: 123 DPKASSSFQANGTKFAIQYGTGRVDGILSEDKLTIGGIKGASVIFGEALWEPSLVFAFAH 182
             + SS+++       + Y  G+ +G L  D L                           
Sbjct: 114 QRQLSSTYRDLRKGVYVPYTQGKWEGELGTDLL--------------------------- 146

Query: 183 FDGILGLGFPILSVEGVRPPMDVLVEQGLLDKPVFSFYLNRDPEEPDGGELVLGGSDPAH 242
                G GFP+   E       VL                       GG +++GG D + 
Sbjct: 147 ----CGAGFPLNQSE-------VLASV--------------------GGSMIIGGIDHSL 175

Query: 243 YIPPLTFVPVTVPAYWQIHMERVKV-GPGLTLCAKGC---AAILDTGTSLITGPTEEIRA 298
           Y   L + P+    Y+++ + RV++ G  L +  K      +I+D+GT+ +  P +   A
Sbjct: 176 YTGSLWYTPIRREWYYEVIIVRVEINGQDLKMDCKEYNYDKSIVDSGTTNLRLPKKVFEA 235


>gi|26986534 Rho GTPase activating protein 12 [Homo sapiens]
          Length = 846

 Score = 30.8 bits (68), Expect = 2.4
 Identities = 20/91 (21%), Positives = 36/91 (39%), Gaps = 6/91 (6%)

Query: 47  WREPAELPKLGAPSPGDKPIFVPLSNYRDVQYF-GEIGLGTPPQNFTVAFDTGSSNLWVP 105
           W   A + K    +PGD+ +     NY    Y   +   G+PP+ ++   D     L+  
Sbjct: 298 WTRDASISKGDFQNPGDQELLSSEENYYSTSYSQSDSQCGSPPRGWSEELDERGHTLYTS 357

Query: 106 SRRCHFFSVPCWLHHRFDPKASSSFQANGTK 136
                 ++   WL H  D      + A+G++
Sbjct: 358 D-----YTNEKWLKHVDDQGRQYYYSADGSR 383


>gi|11321593 insulin-like growth factor binding protein 6 [Homo
          sapiens]
          Length = 240

 Score = 29.3 bits (64), Expect = 7.0
 Identities = 16/30 (53%), Positives = 17/30 (56%)

Query: 1  MSPPPLLQPLLLLLPLLNVEPSGATLIRIP 30
          M+P  LL PLLLLL LL     G  L R P
Sbjct: 1  MTPHRLLPPLLLLLALLLAASPGGALARCP 30


>gi|239753040 PREDICTED: hypothetical protein XP_002345331 [Homo
           sapiens]
          Length = 244

 Score = 29.3 bits (64), Expect = 7.0
 Identities = 33/120 (27%), Positives = 48/120 (40%), Gaps = 11/120 (9%)

Query: 1   MSPPPLLQPLLLLLPLLNVEPSGATLIRI-PLHRVQPGRRILNLLRGWREPAELPKLGAP 59
           + PPPLL PL  LL ++    +GA +  +    R  P  R ++L    R+   L  L A 
Sbjct: 101 LPPPPLLPPLPALLAVMRAPVTGALITVVWCRERSLPSVRSVSLGAMSRDSESLLSLSA- 159

Query: 60  SPGDKPIFVPLSNYRDVQYFGEIGLGTPPQNFTVAFDTGSSNLWVPSRRCHFFSVPCWLH 119
           SP ++   +   +            G PP  F+ A  + S   W  S  C  F    W H
Sbjct: 160 SPSERLGLLSSCS--------PSAAGAPPDGFSPASLSLSFWAWA-SLECRHFIRRFWNH 210


>gi|239747598 PREDICTED: hypothetical protein XP_002347782 [Homo
           sapiens]
          Length = 244

 Score = 29.3 bits (64), Expect = 7.0
 Identities = 33/120 (27%), Positives = 48/120 (40%), Gaps = 11/120 (9%)

Query: 1   MSPPPLLQPLLLLLPLLNVEPSGATLIRI-PLHRVQPGRRILNLLRGWREPAELPKLGAP 59
           + PPPLL PL  LL ++    +GA +  +    R  P  R ++L    R+   L  L A 
Sbjct: 101 LPPPPLLPPLPALLAVMRAPVTGALITVVWCRERSLPSVRSVSLGAMSRDSESLLSLSA- 159

Query: 60  SPGDKPIFVPLSNYRDVQYFGEIGLGTPPQNFTVAFDTGSSNLWVPSRRCHFFSVPCWLH 119
           SP ++   +   +            G PP  F+ A  + S   W  S  C  F    W H
Sbjct: 160 SPSERLGLLSSCS--------PSAAGAPPDGFSPASLSLSFWAWA-SLECRHFIRRFWNH 210


>gi|239741463 PREDICTED: hypothetical protein XP_002342210 [Homo
           sapiens]
          Length = 244

 Score = 29.3 bits (64), Expect = 7.0
 Identities = 33/120 (27%), Positives = 48/120 (40%), Gaps = 11/120 (9%)

Query: 1   MSPPPLLQPLLLLLPLLNVEPSGATLIRI-PLHRVQPGRRILNLLRGWREPAELPKLGAP 59
           + PPPLL PL  LL ++    +GA +  +    R  P  R ++L    R+   L  L A 
Sbjct: 101 LPPPPLLPPLPALLAVMRAPVTGALITVVWCRERSLPSVRSVSLGAMSRDSESLLSLSA- 159

Query: 60  SPGDKPIFVPLSNYRDVQYFGEIGLGTPPQNFTVAFDTGSSNLWVPSRRCHFFSVPCWLH 119
           SP ++   +   +            G PP  F+ A  + S   W  S  C  F    W H
Sbjct: 160 SPSERLGLLSSCS--------PSAAGAPPDGFSPASLSLSFWAWA-SLECRHFIRRFWNH 210


>gi|22507376 G-protein coupled receptor TG1019 [Homo sapiens]
          Length = 423

 Score = 28.9 bits (63), Expect = 9.1
 Identities = 17/37 (45%), Positives = 22/37 (59%), Gaps = 2/37 (5%)

Query: 37 GRRILNLLRG-W-REPAELPKLGAPSPGDKPIFVPLS 71
          GRR+ NLL G W ++P EL  L +PSP      +P S
Sbjct: 24 GRRLQNLLSGPWPKQPMELHNLSSPSPSLSSSVLPPS 60


  Database: hs.faa
    Posted date:  Aug 4, 2009  4:42 PM
  Number of letters in database: 18,247,518
  Number of sequences in database:  37,866
  
Lambda     K      H
   0.323    0.144    0.459 

Gapped
Lambda     K      H
   0.267   0.0410    0.140 


Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Hits to DB: 19,099,087
Number of Sequences: 37866
Number of extensions: 987318
Number of successful extensions: 1773
Number of sequences better than 10.0: 23
Number of HSP's better than 10.0 without gapping: 18
Number of HSP's successfully gapped in prelim test: 5
Number of HSP's that attempted gapping in prelim test: 1718
Number of HSP's gapped (non-prelim): 25
length of query: 420
length of database: 18,247,518
effective HSP length: 105
effective length of query: 315
effective length of database: 14,271,588
effective search space: 4495550220
effective search space used: 4495550220
T: 11
A: 40
X1: 16 ( 7.4 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 41 (21.9 bits)
S2: 63 (28.9 bits)

Search results were obtained with NCBI BLAST and RefSeq entries.


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Guide to the Human Genome
Copyright © 2010 by Stewart Scherer. All rights reserved.

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