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Search of human proteins with 4758624
BLASTP 2.2.11 [Jun-05-2005]
Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer,
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997),
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs", Nucleic Acids Res. 25:3389-3402.
Query= gi|4758624 potassium channel, subfamily K, member 6 [Homo
sapiens]
(313 letters)
Database: hs.faa
37,866 sequences; 18,247,518 total letters
Searching..................................................done
Score E
Sequences producing significant alignments: (bits) Value
gi|4758624 potassium channel, subfamily K, member 6 [Homo sapiens] 620 e-178
gi|4504847 potassium channel, subfamily K, member 1 [Homo sapiens] 250 1e-66
gi|205360983 potassium channel, subfamily K, member 16 isoform 3... 154 1e-37
gi|14149764 potassium channel, subfamily K, member 16 isoform 2 ... 154 1e-37
gi|15718767 TRAAK [Homo sapiens] 150 1e-36
gi|16118231 potassium channel, subfamily K, member 7 isoform A [... 147 2e-35
gi|17025230 potassium channel, subfamily K, member 17 isoform 1 ... 136 2e-32
gi|205360973 potassium channel, subfamily K, member 16 isoform 4... 135 6e-32
gi|205360971 potassium channel, subfamily K, member 16 isoform 1... 134 8e-32
gi|14589851 potassium channel, subfamily K, member 2 isoform b [... 134 1e-31
gi|126365795 potassium channel, subfamily K, member 2 isoform c ... 134 1e-31
gi|62912487 potassium channel, subfamily K, member 2 isoform a [... 134 1e-31
gi|5031821 potassium channel, subfamily K, member 7 isoform C [H... 132 4e-31
gi|16118235 potassium channel, subfamily K, member 7 isoform B [... 132 4e-31
gi|16118233 potassium channel, subfamily K, member 7 isoform B [... 132 4e-31
gi|20143946 potassium channel, subfamily K, member 10 isoform 3 ... 129 3e-30
gi|20143944 potassium channel, subfamily K, member 10 isoform 2 ... 129 3e-30
gi|10863961 potassium channel, subfamily K, member 10 isoform 1 ... 129 3e-30
gi|4504851 potassium channel, subfamily K, member 5 [Homo sapiens] 127 1e-29
gi|205361107 potassium channel, subfamily K, member 17 isoform 2... 117 1e-26
gi|11545761 potassium channel, subfamily K, member 12 [Homo sapi... 115 7e-26
gi|7706135 potassium channel, subfamily K, member 9 [Homo sapiens] 108 8e-24
gi|4504849 potassium channel, subfamily K, member 3 [Homo sapiens] 106 3e-23
gi|11641275 potassium family, subfamily K, member 15 [Homo sapiens] 103 2e-22
gi|16306555 potassium channel, subfamily K, member 13 [Homo sapi... 95 7e-20
gi|32469495 potassium channel, subfamily K, member 18 [Homo sapi... 58 9e-09
gi|236462242 potassium voltage-gated channel, KQT-like subfamily... 43 4e-04
gi|236462079 potassium voltage-gated channel, KQT-like subfamily... 43 4e-04
gi|236461942 potassium voltage-gated channel, KQT-like subfamily... 43 4e-04
gi|236461719 potassium voltage-gated channel, KQT-like subfamily... 43 4e-04
>gi|4758624 potassium channel, subfamily K, member 6 [Homo sapiens]
Length = 313
Score = 620 bits (1600), Expect = e-178
Identities = 313/313 (100%), Positives = 313/313 (100%)
Query: 1 MRRGALLAGALAAYAAYLVLGALLVARLEGPHEARLRAELETLRAQLLQRSPCVAAPALD 60
MRRGALLAGALAAYAAYLVLGALLVARLEGPHEARLRAELETLRAQLLQRSPCVAAPALD
Sbjct: 1 MRRGALLAGALAAYAAYLVLGALLVARLEGPHEARLRAELETLRAQLLQRSPCVAAPALD 60
Query: 61 AFVERVLAAGRLGRVVLANASGSANASDPAWDFASALFFASTLITTVGYGYTTPLTDAGK 120
AFVERVLAAGRLGRVVLANASGSANASDPAWDFASALFFASTLITTVGYGYTTPLTDAGK
Sbjct: 61 AFVERVLAAGRLGRVVLANASGSANASDPAWDFASALFFASTLITTVGYGYTTPLTDAGK 120
Query: 121 AFSIAFALLGVPTTMLLLTASAQRLSLLLTHVPLSWLSMRWGWDPRRAACWHLVALLGVV 180
AFSIAFALLGVPTTMLLLTASAQRLSLLLTHVPLSWLSMRWGWDPRRAACWHLVALLGVV
Sbjct: 121 AFSIAFALLGVPTTMLLLTASAQRLSLLLTHVPLSWLSMRWGWDPRRAACWHLVALLGVV 180
Query: 181 VTVCFLVPAVIFAHLEEAWSFLDAFYFCFISLSTIGLGDYVPGEAPGQPYRALYKVLVTV 240
VTVCFLVPAVIFAHLEEAWSFLDAFYFCFISLSTIGLGDYVPGEAPGQPYRALYKVLVTV
Sbjct: 181 VTVCFLVPAVIFAHLEEAWSFLDAFYFCFISLSTIGLGDYVPGEAPGQPYRALYKVLVTV 240
Query: 241 YLFLGLVAMVLVLQTFRHVSDLHGLTELILLPPPCPASFNADEDDRVDILGPQPESHQQL 300
YLFLGLVAMVLVLQTFRHVSDLHGLTELILLPPPCPASFNADEDDRVDILGPQPESHQQL
Sbjct: 241 YLFLGLVAMVLVLQTFRHVSDLHGLTELILLPPPCPASFNADEDDRVDILGPQPESHQQL 300
Query: 301 SASSHTDYASIPR 313
SASSHTDYASIPR
Sbjct: 301 SASSHTDYASIPR 313
>gi|4504847 potassium channel, subfamily K, member 1 [Homo sapiens]
Length = 336
Score = 250 bits (638), Expect = 1e-66
Identities = 133/297 (44%), Positives = 192/297 (64%), Gaps = 17/297 (5%)
Query: 14 YAAYLVLGALLVARLEGPHEARLRAELETLRAQLLQRSPCVAAPALDAFVERVLAAGRLG 73
Y YLV GA++ + +E P+E LR EL L+ + L+ C++ L+ F+ RVL A G
Sbjct: 30 YLLYLVFGAVVFSSVELPYEDLLRQELRKLKRRFLEEHECLSEQQLEQFLGRVLEASNYG 89
Query: 74 RVVLANASGSANASDPAWDFASALFFASTLITTVGYGYTTPLTDAGKAFSIAFALLGVPT 133
VL+NASG+ N WDF SALFFAST+++T GYG+T PL+D GKAF I ++++G+P
Sbjct: 90 VSVLSNASGNWN-----WDFTSALFFASTVLSTTGYGHTVPLSDGGKAFCIIYSVIGIPF 144
Query: 134 TMLLLTASAQRLSLLLTHVPLSWLSMRWGWDPRRAACWHLVALLGVVVTVCFLVPAVIFA 193
T+L LTA QR+++ +T P+ + +RWG+ + A H V L V V+ F +PA +F+
Sbjct: 145 TLLFLTAVVQRITVHVTRRPVLYFHIRWGFSKQVVAIVHAVLLGFVTVSCFFFIPAAVFS 204
Query: 194 HLEEAWSFLDAFYFCFISLSTIGLGDYVPGEAPGQPYRALYKVLVTVYLFLGLVAMVLVL 253
LE+ W+FL++FYFCFISLSTIGLGDYVPGE Q +R LYK+ +T YL LGL+AM++VL
Sbjct: 205 VLEDDWNFLESFYFCFISLSTIGLGDYVPGEGYNQKFRELYKIGITCYLLLGLIAMLVVL 264
Query: 254 QTFRHVSDLHGLTELILLPPPCPASFNADEDDRVDILGPQPESHQQLSASSHTDYAS 310
+TF + +L ++ + ++D+V I+ H QLS SS TD A+
Sbjct: 265 ETFCELHELKKFRKMFYVK-------KDKDEDQVHII-----EHDQLSFSSITDQAA 309
>gi|205360983 potassium channel, subfamily K, member 16 isoform 3
[Homo sapiens]
Length = 294
Score = 154 bits (389), Expect = 1e-37
Identities = 90/255 (35%), Positives = 140/255 (54%), Gaps = 19/255 (7%)
Query: 4 GALLAGALAAYAAYLVLGALLVARLEGPHEARLRAELETLRAQLLQRSPCVAAPALDAFV 63
G + L AY YL+LGA + LE EA+ R + + + + L+ C+ A++ FV
Sbjct: 11 GGRVLPLLLAYVCYLLLGATIFQLLERQAEAQSRDQFQLEKLRFLENYTCLDQWAMEQFV 70
Query: 64 ERVLAAGRLGRVVLANASGSANASDPAWDFASALFFASTLITTVGYGYTTPLTDAGKAFS 123
+ ++ A G N++ +N WDF S+ FFA T++TT+GYG P T+AG+ F
Sbjct: 71 QVIMEAWVKGVNPKGNSTNPSN-----WDFGSSFFFAGTVVTTIGYGNLAPSTEAGQVFC 125
Query: 124 IAFALLGVPTTMLLLTASAQRLSLLLTHVPLSWLSMRWGWDPRRAACWHLVAL-----LG 178
+ +ALLG+P ++ L L L + RW PRR+ ++ L LG
Sbjct: 126 VFYALLGIPLNVIFLNHLGTGLRAHLAAIE------RWEDRPRRSQVLQVLGLALFLTLG 179
Query: 179 VVVTVCFLVPAVIFAHLEEAWSFLDAFYFCFISLSTIGLGDYVPGEAPGQPYRALYKVLV 238
+V + F P ++F+H+E WSF + FYF FI+LSTIG GDYV G P + Y ++Y+ L
Sbjct: 180 TLVILIF--PPMVFSHVE-GWSFSEGFYFAFITLSTIGFGDYVVGTDPSKHYISVYRSLA 236
Query: 239 TVYLFLGLVAMVLVL 253
+++ LGL + L+L
Sbjct: 237 AIWILLGLAWLALIL 251
>gi|14149764 potassium channel, subfamily K, member 16 isoform 2
[Homo sapiens]
Length = 309
Score = 154 bits (389), Expect = 1e-37
Identities = 90/255 (35%), Positives = 140/255 (54%), Gaps = 19/255 (7%)
Query: 4 GALLAGALAAYAAYLVLGALLVARLEGPHEARLRAELETLRAQLLQRSPCVAAPALDAFV 63
G + L AY YL+LGA + LE EA+ R + + + + L+ C+ A++ FV
Sbjct: 11 GGRVLPLLLAYVCYLLLGATIFQLLERQAEAQSRDQFQLEKLRFLENYTCLDQWAMEQFV 70
Query: 64 ERVLAAGRLGRVVLANASGSANASDPAWDFASALFFASTLITTVGYGYTTPLTDAGKAFS 123
+ ++ A G N++ +N WDF S+ FFA T++TT+GYG P T+AG+ F
Sbjct: 71 QVIMEAWVKGVNPKGNSTNPSN-----WDFGSSFFFAGTVVTTIGYGNLAPSTEAGQVFC 125
Query: 124 IAFALLGVPTTMLLLTASAQRLSLLLTHVPLSWLSMRWGWDPRRAACWHLVAL-----LG 178
+ +ALLG+P ++ L L L + RW PRR+ ++ L LG
Sbjct: 126 VFYALLGIPLNVIFLNHLGTGLRAHLAAIE------RWEDRPRRSQVLQVLGLALFLTLG 179
Query: 179 VVVTVCFLVPAVIFAHLEEAWSFLDAFYFCFISLSTIGLGDYVPGEAPGQPYRALYKVLV 238
+V + F P ++F+H+E WSF + FYF FI+LSTIG GDYV G P + Y ++Y+ L
Sbjct: 180 TLVILIF--PPMVFSHVE-GWSFSEGFYFAFITLSTIGFGDYVVGTDPSKHYISVYRSLA 236
Query: 239 TVYLFLGLVAMVLVL 253
+++ LGL + L+L
Sbjct: 237 AIWILLGLAWLALIL 251
Score = 29.6 bits (65), Expect = 3.6
Identities = 25/82 (30%), Positives = 36/82 (43%), Gaps = 4/82 (4%)
Query: 91 WDFASALFFASTLITTVGYGYTTPLTDAGKAFSIAFALLGVPTTMLLLTASAQRLSL--L 148
W F+ +FA ++T+G+G TD K + + L +L L A L L L
Sbjct: 197 WSFSEGFYFAFITLSTIGFGDYVVGTDPSKHYISVYRSLAAIWILLGLAWLALILPLGPL 256
Query: 149 LTH--VPLSWLSMRWGWDPRRA 168
L H L LS+R G + A
Sbjct: 257 LLHRCCQLWLLSLRQGCGAKAA 278
>gi|15718767 TRAAK [Homo sapiens]
Length = 393
Score = 150 bits (379), Expect = 1e-36
Identities = 107/316 (33%), Positives = 152/316 (48%), Gaps = 47/316 (14%)
Query: 3 RGALLAGALAAYAAYLVLGALLVARLEGPHEARLRAELETLRAQLLQRSPCVAAPALDAF 62
R L LA YLV GAL+ LE PHE + + EL +R + L+ PCV+ L
Sbjct: 2 RSTTLLALLALVLLYLVSGALVFRALEQPHEQQAQRELGEVREKFLRAHPCVSDQELGLL 61
Query: 63 VERVLAAGRLGRVVLANASGSANASDPAWDFASALFFASTLITTVGYGYTTPLTDAGKAF 122
++ V A LG + ++N+S AWD SA FF+ T+ITT+GYG TDAG+ F
Sbjct: 62 IKEV--ADALGGGADPETNSTSNSSHSAWDLGSAFFFSGTIITTIGYGNVALRTDAGRLF 119
Query: 123 SIAFALLGVPTTMLLLTASAQRLSLLLTH--VPLSWLSMRWGWDPR--RAACWHLVALLG 178
I +AL+G+P +LL RL L H + + ++W P R L L+G
Sbjct: 120 CIFYALVGIPLFGILLAGVGDRLGSSLRHGIGHIEAIFLKWHVPPELVRVLSAMLFLLIG 179
Query: 179 VVVTVCFLVPAVIFAHLEEAWSFLDAFYFCFISLSTIGLGDYVPGEAPGQPYRALYKVLV 238
++ V L P +F ++E+ WS L+A YF ++L+T+G GDYV G P Q A Y+ LV
Sbjct: 180 CLLFV--LTPTFVFCYMED-WSKLEAIYFVIVTLTTVGFGDYVAGADPRQDSPA-YQPLV 235
Query: 239 TVYLFLGLVAMVLVLQTF---------RHVSDLHGLT----------------------- 266
++ LGL VL T R +++ GLT
Sbjct: 236 WFWILLGLAYFASVLTTIGNWLRVVSRRTRAEMGGLTAQAASWTGTVTARVTQRAGPAAP 295
Query: 267 -----ELILLPPPCPA 277
+ +L PPPCPA
Sbjct: 296 PPEKEQPLLPPPPCPA 311
>gi|16118231 potassium channel, subfamily K, member 7 isoform A
[Homo sapiens]
Length = 307
Score = 147 bits (370), Expect = 2e-35
Identities = 102/289 (35%), Positives = 150/289 (51%), Gaps = 25/289 (8%)
Query: 11 LAAYAAYLVLGALLVARLEGPHEARLRAELET-LRAQLLQRSPCVAAPALDAFVERVLAA 69
+ A+ L LGA++ LEGP RL+AEL L A + C+ AL+ + LA
Sbjct: 14 VVAHLLALGLGAVVFQALEGPPACRLQAELRAELAAFQAEHRACLPPGALEELLGTALAT 73
Query: 70 GRLGRVVLANASGSANASDPAWDFASALFFASTLITTVGYGYTTPLTDAGKAFSIAFALL 129
G L N+S WD SAL FA++++TT GYG+ PL+ GKAF + +A L
Sbjct: 74 QAHGVSTLGNSSEGRT-----WDLPSALLFAASILTTTGYGHMAPLSPGGKAFCMVYAAL 128
Query: 130 GVPTTMLLLTASAQRLSLLLTHVPLSWLSMRWGWDPRRAACWHLVALLGVVVTVCFLVPA 189
G+P + L L A+ + L + P +W+++ W P RAA VAL +V + L+PA
Sbjct: 129 GLPAS-LALVATLRHCLLPVLSRPRAWVAVHWQLSPARAALLQAVALGLLVASSFVLLPA 187
Query: 190 VIFAHLEEAWSFLDAFYFCFISLSTIGLGDYVPGEAPGQPYRALYKVLVTV-------YL 242
++ L+ S L A YFCF SLSTIGL D +PG R+L+ V+ + YL
Sbjct: 188 LVLWGLQGDCSLLGAVYFCFSSLSTIGLEDLLPGRG-----RSLHPVIYHLGQLALLGYL 242
Query: 243 FLGLVAMVLVLQTFRHVSDLHGLTELILLPPPCPASFNADEDDRVDILG 291
LGL+AM+L ++TF + + + + P A +D+ ILG
Sbjct: 243 LLGLLAMLLAVETFSELPQVRAMGKFFRPSGPVTA------EDQGGILG 285
>gi|17025230 potassium channel, subfamily K, member 17 isoform 1
[Homo sapiens]
Length = 332
Score = 136 bits (343), Expect = 2e-32
Identities = 84/248 (33%), Positives = 133/248 (53%), Gaps = 16/248 (6%)
Query: 11 LAAYAAYLVLGALLVARLEGPHEARLRAELETLRAQLLQRSPCVAAPALDAFVERVLAAG 70
L AY AYL LG + LEG + + +LLQ C+ PALD+ + V+ A
Sbjct: 26 LLAYLAYLALGTGVFWTLEGRAAQDSSRSFQRDKWELLQNFTCLDRPALDSLIRDVVQAY 85
Query: 71 RLGRVVLANASGSANASDPAWDFASALFFASTLITTVGYGYTTPLTDAGKAFSIAFALLG 130
+ G +L+N + W+ + FF+ + ITT+GYG +P T A + F I FAL+G
Sbjct: 86 KNGASLLSNTTSMGR-----WELVGSFFFSVSTITTIGYGNLSPNTMAARLFCIFFALVG 140
Query: 131 VPTTMLLLTASAQRLSLLLTHVPLSWLSMRWG-WDPRRAACWHLVALLGVVVT---VCFL 186
+P +++L RL L+ W S G W A W +A G +++ + L
Sbjct: 141 IPLNLVVLN----RLGHLMQQGVNHWASRLGGTWQDPDKARW--LAGSGALLSGLLLFLL 194
Query: 187 VPAVIFAHLEEAWSFLDAFYFCFISLSTIGLGDYVPGEAPGQPYRALYKVLVTVYLFLGL 246
+P ++F+H+E WS+ + FYF FI+LST+G GDYV G P Q Y YK +V++++ G+
Sbjct: 195 LPPLLFSHME-GWSYTEGFYFAFITLSTVGFGDYVIGMNPSQRYPLWYKNMVSLWILFGM 253
Query: 247 VAMVLVLQ 254
+ L+++
Sbjct: 254 AWLALIIK 261
>gi|205360973 potassium channel, subfamily K, member 16 isoform 4
[Homo sapiens]
Length = 262
Score = 135 bits (339), Expect = 6e-32
Identities = 82/229 (35%), Positives = 123/229 (53%), Gaps = 19/229 (8%)
Query: 4 GALLAGALAAYAAYLVLGALLVARLEGPHEARLRAELETLRAQLLQRSPCVAAPALDAFV 63
G + L AY YL+LGA + LE EA+ R + + + + L+ C+ A++ FV
Sbjct: 11 GGRVLPLLLAYVCYLLLGATIFQLLERQAEAQSRDQFQLEKLRFLENYTCLDQWAMEQFV 70
Query: 64 ERVLAAGRLGRVVLANASGSANASDPAWDFASALFFASTLITTVGYGYTTPLTDAGKAFS 123
+ ++ A G N++ +N WDF S+ FFA T++TT+GYG P T+AG+ F
Sbjct: 71 QVIMEAWVKGVNPKGNSTNPSN-----WDFGSSFFFAGTVVTTIGYGNLAPSTEAGQVFC 125
Query: 124 IAFALLGVPTTMLLLTASAQRLSLLLTHVPLSWLSMRWGWDPRRAACWHLVAL-----LG 178
+ +ALLG+P ++ L L L + RW PRR+ ++ L LG
Sbjct: 126 VFYALLGIPLNVIFLNHLGTGLRAHLAAIE------RWEDRPRRSQVLQVLGLALFLTLG 179
Query: 179 VVVTVCFLVPAVIFAHLEEAWSFLDAFYFCFISLSTIGLGDYVPGEAPG 227
+V + F P ++F+H+ E WSF + FYF FI+LSTIG GDYV G G
Sbjct: 180 TLVILIF--PPMVFSHV-EGWSFSEGFYFAFITLSTIGFGDYVVGLRQG 225
Score = 31.2 bits (69), Expect = 1.2
Identities = 13/39 (33%), Positives = 20/39 (51%)
Query: 199 WSFLDAFYFCFISLSTIGLGDYVPGEAPGQPYRALYKVL 237
W F +F+F ++TIG G+ P GQ + Y +L
Sbjct: 93 WDFGSSFFFAGTVVTTIGYGNLAPSTEAGQVFCVFYALL 131
>gi|205360971 potassium channel, subfamily K, member 16 isoform 1
[Homo sapiens]
Length = 322
Score = 134 bits (338), Expect = 8e-32
Identities = 81/225 (36%), Positives = 122/225 (54%), Gaps = 19/225 (8%)
Query: 4 GALLAGALAAYAAYLVLGALLVARLEGPHEARLRAELETLRAQLLQRSPCVAAPALDAFV 63
G + L AY YL+LGA + LE EA+ R + + + + L+ C+ A++ FV
Sbjct: 11 GGRVLPLLLAYVCYLLLGATIFQLLERQAEAQSRDQFQLEKLRFLENYTCLDQWAMEQFV 70
Query: 64 ERVLAAGRLGRVVLANASGSANASDPAWDFASALFFASTLITTVGYGYTTPLTDAGKAFS 123
+ ++ A G N++ +N WDF S+ FFA T++TT+GYG P T+AG+ F
Sbjct: 71 QVIMEAWVKGVNPKGNSTNPSN-----WDFGSSFFFAGTVVTTIGYGNLAPSTEAGQVFC 125
Query: 124 IAFALLGVPTTMLLLTASAQRLSLLLTHVPLSWLSMRWGWDPRRAACWHLVAL-----LG 178
+ +ALLG+P ++ L L L + RW PRR+ ++ L LG
Sbjct: 126 VFYALLGIPLNVIFLNHLGTGLRAHLAAIE------RWEDRPRRSQVLQVLGLALFLTLG 179
Query: 179 VVVTVCFLVPAVIFAHLEEAWSFLDAFYFCFISLSTIGLGDYVPG 223
+V + F P ++F+H+ E WSF + FYF FI+LSTIG GDYV G
Sbjct: 180 TLVILIF--PPMVFSHV-EGWSFSEGFYFAFITLSTIGFGDYVVG 221
Score = 31.2 bits (69), Expect = 1.2
Identities = 13/39 (33%), Positives = 20/39 (51%)
Query: 199 WSFLDAFYFCFISLSTIGLGDYVPGEAPGQPYRALYKVL 237
W F +F+F ++TIG G+ P GQ + Y +L
Sbjct: 93 WDFGSSFFFAGTVVTTIGYGNLAPSTEAGQVFCVFYALL 131
>gi|14589851 potassium channel, subfamily K, member 2 isoform b
[Homo sapiens]
Length = 411
Score = 134 bits (337), Expect = 1e-31
Identities = 83/241 (34%), Positives = 125/241 (51%), Gaps = 12/241 (4%)
Query: 17 YLVLGALLVARLEGPHEARLRAELETLRAQLLQRSPCVAAPALDAFVERVLAAGRLGRVV 76
YL++GA + LE PHE R + + + + CV + LD +++++AA G +
Sbjct: 57 YLIIGATVFKALEQPHEISQRTTIVIQKQTFISQHSCVNSTELDELIQQIVAAINAGIIP 116
Query: 77 LANASGSANASDPAWDFASALFFASTLITTVGYGYTTPLTDAGKAFSIAFALLGVPTTML 136
L N S + WD S+ FFA T+ITT+G+G +P T+ GK F I +ALLG+P
Sbjct: 117 LGNTSNQISH----WDLGSSFFFAGTVITTIGFGNISPRTEGGKIFCIIYALLGIPLFGF 172
Query: 137 LLTASAQRLSLL----LTHVPLSWLSMRWGWDPRRAACWHLVALLGVVVTVCFLVPAVIF 192
LL +L + + V +++ R + L G V+ V +PA+IF
Sbjct: 173 LLAGVGDQLGTIFGKGIAKVEDTFIKWNVSQTKIRIISTIIFILFGCVLFVA--LPAIIF 230
Query: 193 AHLEEAWSFLDAFYFCFISLSTIGLGDYVPGEAPGQPYRALYKVLVTVYLFLGLVAMVLV 252
H+ E WS LDA YF I+L+TIG GDYV G + + Y YK +V ++ +GL V
Sbjct: 231 KHI-EGWSALDAIYFVVITLTTIGFGDYVAGGSDIE-YLDFYKPVVWFWILVGLAYFAAV 288
Query: 253 L 253
L
Sbjct: 289 L 289
>gi|126365795 potassium channel, subfamily K, member 2 isoform c
[Homo sapiens]
Length = 426
Score = 134 bits (337), Expect = 1e-31
Identities = 83/241 (34%), Positives = 125/241 (51%), Gaps = 12/241 (4%)
Query: 17 YLVLGALLVARLEGPHEARLRAELETLRAQLLQRSPCVAAPALDAFVERVLAAGRLGRVV 76
YL++GA + LE PHE R + + + + CV + LD +++++AA G +
Sbjct: 72 YLIIGATVFKALEQPHEISQRTTIVIQKQTFISQHSCVNSTELDELIQQIVAAINAGIIP 131
Query: 77 LANASGSANASDPAWDFASALFFASTLITTVGYGYTTPLTDAGKAFSIAFALLGVPTTML 136
L N S + WD S+ FFA T+ITT+G+G +P T+ GK F I +ALLG+P
Sbjct: 132 LGNTSNQISH----WDLGSSFFFAGTVITTIGFGNISPRTEGGKIFCIIYALLGIPLFGF 187
Query: 137 LLTASAQRLSLL----LTHVPLSWLSMRWGWDPRRAACWHLVALLGVVVTVCFLVPAVIF 192
LL +L + + V +++ R + L G V+ V +PA+IF
Sbjct: 188 LLAGVGDQLGTIFGKGIAKVEDTFIKWNVSQTKIRIISTIIFILFGCVLFVA--LPAIIF 245
Query: 193 AHLEEAWSFLDAFYFCFISLSTIGLGDYVPGEAPGQPYRALYKVLVTVYLFLGLVAMVLV 252
H+ E WS LDA YF I+L+TIG GDYV G + + Y YK +V ++ +GL V
Sbjct: 246 KHI-EGWSALDAIYFVVITLTTIGFGDYVAGGSDIE-YLDFYKPVVWFWILVGLAYFAAV 303
Query: 253 L 253
L
Sbjct: 304 L 304
>gi|62912487 potassium channel, subfamily K, member 2 isoform a
[Homo sapiens]
Length = 422
Score = 134 bits (337), Expect = 1e-31
Identities = 83/241 (34%), Positives = 125/241 (51%), Gaps = 12/241 (4%)
Query: 17 YLVLGALLVARLEGPHEARLRAELETLRAQLLQRSPCVAAPALDAFVERVLAAGRLGRVV 76
YL++GA + LE PHE R + + + + CV + LD +++++AA G +
Sbjct: 68 YLIIGATVFKALEQPHEISQRTTIVIQKQTFISQHSCVNSTELDELIQQIVAAINAGIIP 127
Query: 77 LANASGSANASDPAWDFASALFFASTLITTVGYGYTTPLTDAGKAFSIAFALLGVPTTML 136
L N S + WD S+ FFA T+ITT+G+G +P T+ GK F I +ALLG+P
Sbjct: 128 LGNTSNQISH----WDLGSSFFFAGTVITTIGFGNISPRTEGGKIFCIIYALLGIPLFGF 183
Query: 137 LLTASAQRLSLL----LTHVPLSWLSMRWGWDPRRAACWHLVALLGVVVTVCFLVPAVIF 192
LL +L + + V +++ R + L G V+ V +PA+IF
Sbjct: 184 LLAGVGDQLGTIFGKGIAKVEDTFIKWNVSQTKIRIISTIIFILFGCVLFVA--LPAIIF 241
Query: 193 AHLEEAWSFLDAFYFCFISLSTIGLGDYVPGEAPGQPYRALYKVLVTVYLFLGLVAMVLV 252
H+ E WS LDA YF I+L+TIG GDYV G + + Y YK +V ++ +GL V
Sbjct: 242 KHI-EGWSALDAIYFVVITLTTIGFGDYVAGGSDIE-YLDFYKPVVWFWILVGLAYFAAV 299
Query: 253 L 253
L
Sbjct: 300 L 300
>gi|5031821 potassium channel, subfamily K, member 7 isoform C [Homo
sapiens]
Length = 257
Score = 132 bits (332), Expect = 4e-31
Identities = 86/228 (37%), Positives = 123/228 (53%), Gaps = 12/228 (5%)
Query: 11 LAAYAAYLVLGALLVARLEGPHEARLRAELET-LRAQLLQRSPCVAAPALDAFVERVLAA 69
+ A+ L LGA++ LEGP RL+AEL L A + C+ AL+ + LA
Sbjct: 14 VVAHLLALGLGAVVFQALEGPPACRLQAELRAELAAFQAEHRACLPPGALEELLGTALAT 73
Query: 70 GRLGRVVLANASGSANASDPAWDFASALFFASTLITTVGYGYTTPLTDAGKAFSIAFALL 129
G L N+S WD SAL FA++++TT GYG+ PL+ GKAF + +A L
Sbjct: 74 QAHGVSTLGNSSEGRT-----WDLPSALLFAASILTTTGYGHMAPLSPGGKAFCMVYAAL 128
Query: 130 GVPTTMLLLTASAQRLSLLLTHVPLSWLSMRWGWDPRRAACWHLVALLGVVVTVCFLVPA 189
G+P + L L A+ + L + P +W+++ W P RAA VAL +V + L+PA
Sbjct: 129 GLPAS-LALVATLRHCLLPVLSRPRAWVAVHWQLSPARAALLQAVALGLLVASSFVLLPA 187
Query: 190 VIFAHLEEAWSFLDAFYFCFISLSTIGLGDYVPGEAPGQPYRALYKVL 237
++ L+ S L A YFCF SLSTIGL D +PG R+L+ V+
Sbjct: 188 LVLWGLQGDCSLLGAVYFCFSSLSTIGLEDLLPGRG-----RSLHPVI 230
Score = 28.5 bits (62), Expect = 8.0
Identities = 19/60 (31%), Positives = 23/60 (38%), Gaps = 7/60 (11%)
Query: 199 WSFLDAFYFCFISLSTIGLGDYVPGEAPGQPYRALYKVLVTVYLFLGLVAMVLVLQTFRH 258
W A F L+T G G P G K VY LGL A + ++ T RH
Sbjct: 90 WDLPSALLFAASILTTTGYGHMAPLSPGG-------KAFCMVYAALGLPASLALVATLRH 142
>gi|16118235 potassium channel, subfamily K, member 7 isoform B
[Homo sapiens]
Length = 252
Score = 132 bits (332), Expect = 4e-31
Identities = 86/228 (37%), Positives = 123/228 (53%), Gaps = 12/228 (5%)
Query: 11 LAAYAAYLVLGALLVARLEGPHEARLRAELET-LRAQLLQRSPCVAAPALDAFVERVLAA 69
+ A+ L LGA++ LEGP RL+AEL L A + C+ AL+ + LA
Sbjct: 14 VVAHLLALGLGAVVFQALEGPPACRLQAELRAELAAFQAEHRACLPPGALEELLGTALAT 73
Query: 70 GRLGRVVLANASGSANASDPAWDFASALFFASTLITTVGYGYTTPLTDAGKAFSIAFALL 129
G L N+S WD SAL FA++++TT GYG+ PL+ GKAF + +A L
Sbjct: 74 QAHGVSTLGNSSEGRT-----WDLPSALLFAASILTTTGYGHMAPLSPGGKAFCMVYAAL 128
Query: 130 GVPTTMLLLTASAQRLSLLLTHVPLSWLSMRWGWDPRRAACWHLVALLGVVVTVCFLVPA 189
G+P + L L A+ + L + P +W+++ W P RAA VAL +V + L+PA
Sbjct: 129 GLPAS-LALVATLRHCLLPVLSRPRAWVAVHWQLSPARAALLQAVALGLLVASSFVLLPA 187
Query: 190 VIFAHLEEAWSFLDAFYFCFISLSTIGLGDYVPGEAPGQPYRALYKVL 237
++ L+ S L A YFCF SLSTIGL D +PG R+L+ V+
Sbjct: 188 LVLWGLQGDCSLLGAVYFCFSSLSTIGLEDLLPGRG-----RSLHPVI 230
Score = 28.5 bits (62), Expect = 8.0
Identities = 19/60 (31%), Positives = 23/60 (38%), Gaps = 7/60 (11%)
Query: 199 WSFLDAFYFCFISLSTIGLGDYVPGEAPGQPYRALYKVLVTVYLFLGLVAMVLVLQTFRH 258
W A F L+T G G P G K VY LGL A + ++ T RH
Sbjct: 90 WDLPSALLFAASILTTTGYGHMAPLSPGG-------KAFCMVYAALGLPASLALVATLRH 142
>gi|16118233 potassium channel, subfamily K, member 7 isoform B
[Homo sapiens]
Length = 252
Score = 132 bits (332), Expect = 4e-31
Identities = 86/228 (37%), Positives = 123/228 (53%), Gaps = 12/228 (5%)
Query: 11 LAAYAAYLVLGALLVARLEGPHEARLRAELET-LRAQLLQRSPCVAAPALDAFVERVLAA 69
+ A+ L LGA++ LEGP RL+AEL L A + C+ AL+ + LA
Sbjct: 14 VVAHLLALGLGAVVFQALEGPPACRLQAELRAELAAFQAEHRACLPPGALEELLGTALAT 73
Query: 70 GRLGRVVLANASGSANASDPAWDFASALFFASTLITTVGYGYTTPLTDAGKAFSIAFALL 129
G L N+S WD SAL FA++++TT GYG+ PL+ GKAF + +A L
Sbjct: 74 QAHGVSTLGNSSEGRT-----WDLPSALLFAASILTTTGYGHMAPLSPGGKAFCMVYAAL 128
Query: 130 GVPTTMLLLTASAQRLSLLLTHVPLSWLSMRWGWDPRRAACWHLVALLGVVVTVCFLVPA 189
G+P + L L A+ + L + P +W+++ W P RAA VAL +V + L+PA
Sbjct: 129 GLPAS-LALVATLRHCLLPVLSRPRAWVAVHWQLSPARAALLQAVALGLLVASSFVLLPA 187
Query: 190 VIFAHLEEAWSFLDAFYFCFISLSTIGLGDYVPGEAPGQPYRALYKVL 237
++ L+ S L A YFCF SLSTIGL D +PG R+L+ V+
Sbjct: 188 LVLWGLQGDCSLLGAVYFCFSSLSTIGLEDLLPGRG-----RSLHPVI 230
Score = 28.5 bits (62), Expect = 8.0
Identities = 19/60 (31%), Positives = 23/60 (38%), Gaps = 7/60 (11%)
Query: 199 WSFLDAFYFCFISLSTIGLGDYVPGEAPGQPYRALYKVLVTVYLFLGLVAMVLVLQTFRH 258
W A F L+T G G P G K VY LGL A + ++ T RH
Sbjct: 90 WDLPSALLFAASILTTTGYGHMAPLSPGG-------KAFCMVYAALGLPASLALVATLRH 142
>gi|20143946 potassium channel, subfamily K, member 10 isoform 3
[Homo sapiens]
Length = 543
Score = 129 bits (324), Expect = 3e-30
Identities = 80/241 (33%), Positives = 122/241 (50%), Gaps = 11/241 (4%)
Query: 17 YLVLGALLVARLEGPHEARLRAELETLRAQLLQRSPCVAAPALDAFVERVLAAGRLGRVV 76
YLV G L+ LE P E+ + + +A+ L+ CV+ L+ ++ L A G
Sbjct: 87 YLVTGGLVFRALEQPFESSQKNTIALEKAEFLRDHVCVSPQELETLIQHALDADNAGVSP 146
Query: 77 LANASGSANASDPAWDFASALFFASTLITTVGYGYTTPLTDAGKAFSIAFALLGVPTTML 136
+ N+S +++ WD SA FFA T+ITT+GYG P T+ GK F I +A+ G+P
Sbjct: 147 IGNSSNNSSH----WDLGSAFFFAGTVITTIGYGNIAPSTEGGKIFCILYAIFGIPLFGF 202
Query: 137 LLTASAQRLSLL----LTHVPLSWLSMRWGWDPRRAACWHLVALLGVVVTVCFLVPAVIF 192
LL +L + + V + + R L L G +V V +PAVIF
Sbjct: 203 LLAGIGDQLGTIFGKSIARVEKVFRKKQVSQTKIRVISTILFILAGCIVFV--TIPAVIF 260
Query: 193 AHLEEAWSFLDAFYFCFISLSTIGLGDYVPGEAPGQPYRALYKVLVTVYLFLGLVAMVLV 252
++ E W+ L++ YF ++L+T+G GD+V G G YR YK LV ++ +GL V
Sbjct: 261 KYI-EGWTALESIYFVVVTLTTVGFGDFVAGGNAGINYREWYKPLVWFWILVGLAYFAAV 319
Query: 253 L 253
L
Sbjct: 320 L 320
>gi|20143944 potassium channel, subfamily K, member 10 isoform 2
[Homo sapiens]
Length = 543
Score = 129 bits (324), Expect = 3e-30
Identities = 80/241 (33%), Positives = 122/241 (50%), Gaps = 11/241 (4%)
Query: 17 YLVLGALLVARLEGPHEARLRAELETLRAQLLQRSPCVAAPALDAFVERVLAAGRLGRVV 76
YLV G L+ LE P E+ + + +A+ L+ CV+ L+ ++ L A G
Sbjct: 87 YLVTGGLVFRALEQPFESSQKNTIALEKAEFLRDHVCVSPQELETLIQHALDADNAGVSP 146
Query: 77 LANASGSANASDPAWDFASALFFASTLITTVGYGYTTPLTDAGKAFSIAFALLGVPTTML 136
+ N+S +++ WD SA FFA T+ITT+GYG P T+ GK F I +A+ G+P
Sbjct: 147 IGNSSNNSSH----WDLGSAFFFAGTVITTIGYGNIAPSTEGGKIFCILYAIFGIPLFGF 202
Query: 137 LLTASAQRLSLL----LTHVPLSWLSMRWGWDPRRAACWHLVALLGVVVTVCFLVPAVIF 192
LL +L + + V + + R L L G +V V +PAVIF
Sbjct: 203 LLAGIGDQLGTIFGKSIARVEKVFRKKQVSQTKIRVISTILFILAGCIVFV--TIPAVIF 260
Query: 193 AHLEEAWSFLDAFYFCFISLSTIGLGDYVPGEAPGQPYRALYKVLVTVYLFLGLVAMVLV 252
++ E W+ L++ YF ++L+T+G GD+V G G YR YK LV ++ +GL V
Sbjct: 261 KYI-EGWTALESIYFVVVTLTTVGFGDFVAGGNAGINYREWYKPLVWFWILVGLAYFAAV 319
Query: 253 L 253
L
Sbjct: 320 L 320
>gi|10863961 potassium channel, subfamily K, member 10 isoform 1
[Homo sapiens]
Length = 538
Score = 129 bits (324), Expect = 3e-30
Identities = 80/241 (33%), Positives = 122/241 (50%), Gaps = 11/241 (4%)
Query: 17 YLVLGALLVARLEGPHEARLRAELETLRAQLLQRSPCVAAPALDAFVERVLAAGRLGRVV 76
YLV G L+ LE P E+ + + +A+ L+ CV+ L+ ++ L A G
Sbjct: 82 YLVTGGLVFRALEQPFESSQKNTIALEKAEFLRDHVCVSPQELETLIQHALDADNAGVSP 141
Query: 77 LANASGSANASDPAWDFASALFFASTLITTVGYGYTTPLTDAGKAFSIAFALLGVPTTML 136
+ N+S +++ WD SA FFA T+ITT+GYG P T+ GK F I +A+ G+P
Sbjct: 142 IGNSSNNSSH----WDLGSAFFFAGTVITTIGYGNIAPSTEGGKIFCILYAIFGIPLFGF 197
Query: 137 LLTASAQRLSLL----LTHVPLSWLSMRWGWDPRRAACWHLVALLGVVVTVCFLVPAVIF 192
LL +L + + V + + R L L G +V V +PAVIF
Sbjct: 198 LLAGIGDQLGTIFGKSIARVEKVFRKKQVSQTKIRVISTILFILAGCIVFV--TIPAVIF 255
Query: 193 AHLEEAWSFLDAFYFCFISLSTIGLGDYVPGEAPGQPYRALYKVLVTVYLFLGLVAMVLV 252
++ E W+ L++ YF ++L+T+G GD+V G G YR YK LV ++ +GL V
Sbjct: 256 KYI-EGWTALESIYFVVVTLTTVGFGDFVAGGNAGINYREWYKPLVWFWILVGLAYFAAV 314
Query: 253 L 253
L
Sbjct: 315 L 315
>gi|4504851 potassium channel, subfamily K, member 5 [Homo sapiens]
Length = 499
Score = 127 bits (320), Expect = 1e-29
Identities = 82/256 (32%), Positives = 128/256 (50%), Gaps = 26/256 (10%)
Query: 3 RGALLAGALAAYAAYLVLGALLVARLEGPHEARLRAELETLRAQLLQRSPCVAAPALDAF 62
RG LL A+ Y L +GA + LE PH + T + LL+ PC+ LD
Sbjct: 4 RGPLLTSAIIFY---LAIGAAIFEVLEEPHWKEAKKNYYTQKLHLLKEFPCLGQEGLDKI 60
Query: 63 VERVLAAGRLGRVVLANASGSANASDPAWDFASALFFASTLITTVGYGYTTPLTDAGKAF 122
+E V A G + N + + W++ +A+ FA+T+ITT+GYG P T AG+ F
Sbjct: 61 LEVVSDAAGQGVAITGNQTFNN------WNWPNAMIFAATVITTIGYGNVAPKTPAGRLF 114
Query: 123 SIAFALLGVPTTMLLLTA-------SAQRLSLLLTHVPLSWLSMRWGWDPRRAACWHLVA 175
+ + L GVP + ++A A+RL LT + G R+A V
Sbjct: 115 CVFYGLFGVPLCLTWISALGKFFGGRAKRLGQFLT---------KRGVSLRKAQITCTVI 165
Query: 176 LLGVVVTVCFLVPAVIFAHLEEAWSFLDAFYFCFISLSTIGLGDYVPGEAPGQPYRALYK 235
+ V V ++P +F + E W++++ Y+ FI++STIG GD+V G P Y ALY+
Sbjct: 166 FIVWGVLVHLVIPPFVFM-VTEGWNYIEGLYYSFITISTIGFGDFVAGVNPSANYHALYR 224
Query: 236 VLVTVYLFLGLVAMVL 251
V ++++LGL + L
Sbjct: 225 YFVELWIYLGLAWLSL 240
>gi|205361107 potassium channel, subfamily K, member 17 isoform 2
[Homo sapiens]
Length = 271
Score = 117 bits (294), Expect = 1e-26
Identities = 75/215 (34%), Positives = 114/215 (53%), Gaps = 16/215 (7%)
Query: 11 LAAYAAYLVLGALLVARLEGPHEARLRAELETLRAQLLQRSPCVAAPALDAFVERVLAAG 70
L AY AYL LG + LEG + + +LLQ C+ PALD+ + V+ A
Sbjct: 26 LLAYLAYLALGTGVFWTLEGRAAQDSSRSFQRDKWELLQNFTCLDRPALDSLIRDVVQAY 85
Query: 71 RLGRVVLANASGSANASDPAWDFASALFFASTLITTVGYGYTTPLTDAGKAFSIAFALLG 130
+ G +L+N + W+ + FF+ + ITT+GYG +P T A + F I FAL+G
Sbjct: 86 KNGASLLSNTTSMGR-----WELVGSFFFSVSTITTIGYGNLSPNTMAARLFCIFFALVG 140
Query: 131 VPTTMLLLTASAQRLSLLLTHVPLSWLSMRWG-WDPRRAACWHLVALLGVVVT---VCFL 186
+P +++L RL L+ W S G W A W +A G +++ + L
Sbjct: 141 IPLNLVVL----NRLGHLMQQGVNHWASRLGGTWQDPDKARW--LAGSGALLSGLLLFLL 194
Query: 187 VPAVIFAHLEEAWSFLDAFYFCFISLSTIGLGDYV 221
+P ++F+H+ E WS+ + FYF FI+LST+G GDYV
Sbjct: 195 LPPLLFSHM-EGWSYTEGFYFAFITLSTVGFGDYV 228
>gi|11545761 potassium channel, subfamily K, member 12 [Homo
sapiens]
Length = 430
Score = 115 bits (287), Expect = 7e-26
Identities = 80/259 (30%), Positives = 120/259 (46%), Gaps = 38/259 (14%)
Query: 12 AAYAAYLVLGALLVARLEGPHEARLRAEL-ETLRAQLLQRSPCVAAPALDAFVERVLAAG 70
A YLV GA + + LE P EA RA TLR + VA P L AF+ AA
Sbjct: 44 ALIGLYLVAGATVFSALESPGEAEARARWGATLRN--FSAAHGVAEPELRAFLRHYEAA- 100
Query: 71 RLGRVVLANASGSANASDPAWDFASALFFASTLITTVGYGYTTPLTDAGKAFSIAFALLG 130
A A+A P WDF A +F T+++T+G+G TTP T GKAF IA+ L G
Sbjct: 101 -------LAAGVRADALRPRWDFPGAFYFVGTVVSTIGFGMTTPATVGGKAFLIAYGLFG 153
Query: 131 VPTTMLLLTASAQRLSLLLTHV-----------------------PLSWLSMRWGWDPRR 167
T+L +R+ LL + LS GW P
Sbjct: 154 CAGTILFFNLFLERIISLLAFIMRACRERQLRRSGLLPATFRRGSALSEADSLAGWKP-- 211
Query: 168 AACWHLVALLGVVVTVCFLVPAVIFAHLEEAWSFLDAFYFCFISLSTIGLGDYVPGEAPG 227
+ +H++ +LG+ + + ++ + E W ++D+ YFCF++ STIG GD V +
Sbjct: 212 -SVYHVLLILGLFAVLLSCCASAMYTSV-EGWDYVDSLYFCFVTFSTIGFGDLVSSQHAA 269
Query: 228 QPYRALYKVLVTVYLFLGL 246
+ LY++ +++ LG+
Sbjct: 270 YRNQGLYRLGNFLFILLGV 288
>gi|7706135 potassium channel, subfamily K, member 9 [Homo sapiens]
Length = 374
Score = 108 bits (269), Expect = 8e-24
Identities = 75/236 (31%), Positives = 124/236 (52%), Gaps = 21/236 (8%)
Query: 17 YLVLGALLVARLEGPHEARLRAELETLRAQLLQRSPCVAAPALDAFVERVLAAGRLGRVV 76
YL++GA + LE HE R E E L+A+ ++ + D +L V+
Sbjct: 18 YLLVGAAVFDALESDHEMR---EEEKLKAEEIRIKGKYNISSEDY--------RQLELVI 66
Query: 77 LANASGSANASDPAWDFASALFFASTLITTVGYGYTTPLTDAGKAFSIAFALLGVPTTML 136
L + A W FA + +FA T+ITT+GYG+ P TDAGKAF + +A+LG+P T++
Sbjct: 67 LQSEPHRAGVQ---WKFAGSFYFAITVITTIGYGHAAPGTDAGKAFCMFYAVLGIPLTLV 123
Query: 137 LLTASAQRLSLLLTHVPLSWLSMRWGWDPRRAACWHLVAL--LGVVVTVCFLVPAVIFAH 194
+ + +R++ + ++ L + G + ++V + + T+C + A F+
Sbjct: 124 MFQSLGERMNTFVRYL-LKRIKKCCGMRNTDVSMENMVTVGFFSCMGTLC--IGAAAFSQ 180
Query: 195 LEEAWSFLDAFYFCFISLSTIGLGDYVPGEAPGQ-PYRALYKVLVTVYLFLGLVAM 249
EE WSF A+Y+CFI+L+TIG GDYV + G + LY +Y+ +GL +
Sbjct: 181 CEE-WSFFHAYYYCFITLTTIGFGDYVALQTKGALQKKPLYVAFSFMYILVGLTVI 235
>gi|4504849 potassium channel, subfamily K, member 3 [Homo sapiens]
Length = 394
Score = 106 bits (264), Expect = 3e-23
Identities = 74/208 (35%), Positives = 106/208 (50%), Gaps = 22/208 (10%)
Query: 17 YLVLGALLVARLEGPHEARLRAELETLRAQLLQRSPCVAAPALDAFVERVLAAGRLGRVV 76
YL++GA + LE E R LE LR Q L+ ++ + L RVV
Sbjct: 18 YLLVGAAVFDALESEPELIERQRLE-LRQQELRARYNLSQGGYE----------ELERVV 66
Query: 77 LANASGSANASDPAWDFASALFFASTLITTVGYGYTTPLTDAGKAFSIAFALLGVPTTML 136
L A W FA + +FA T+ITT+GYG+ P TD GK F + +ALLG+P T++
Sbjct: 67 LRLKPHKAGVQ---WRFAGSFYFAITVITTIGYGHAAPSTDGGKVFCMFYALLGIPLTLV 123
Query: 137 LLTASAQRLSLL---LTHVPLSWLSMRWGWDPRRAACWHLVALLGVVVTVCFLVPAVIFA 193
+ + +R++ L L H L MR A L+ + T+C + A F+
Sbjct: 124 MFQSLGERINTLVRYLLHRAKKGLGMRRA--DVSMANMVLIGFFSCISTLC--IGAAAFS 179
Query: 194 HLEEAWSFLDAFYFCFISLSTIGLGDYV 221
H E W+F A+Y+CFI+L+TIG GDYV
Sbjct: 180 HYEH-WTFFQAYYYCFITLTTIGFGDYV 206
Score = 31.6 bits (70), Expect = 0.95
Identities = 16/51 (31%), Positives = 25/51 (49%), Gaps = 3/51 (5%)
Query: 199 WSFLDAFYFCFISLSTIGLGDYVPGEAPGQPYRALYKVL---VTVYLFLGL 246
W F +FYF ++TIG G P G+ + Y +L +T+ +F L
Sbjct: 78 WRFAGSFYFAITVITTIGYGHAAPSTDGGKVFCMFYALLGIPLTLVMFQSL 128
>gi|11641275 potassium family, subfamily K, member 15 [Homo sapiens]
Length = 330
Score = 103 bits (257), Expect = 2e-22
Identities = 77/254 (30%), Positives = 124/254 (48%), Gaps = 24/254 (9%)
Query: 1 MRRGAL-LAGALAAYAAYLVLGALLVARLEGPHEARLRAELETLRAQLLQRSPCVAAPAL 59
MRR ++ AG + YL++GA + LE +E E+ R +LL +
Sbjct: 1 MRRPSVRAAGLVLCTLCYLLVGAAVFDALE--------SEAESGRQRLLVQKRGALRRKF 52
Query: 60 DAFVERVLAAGRLGRVVLANASGSANASDPAWDFASALFFASTLITTVGYGYTTPLTDAG 119
E RL + +G W F + +FA T+ITT+GYG+ P TD+G
Sbjct: 53 GFSAEDYRELERLALQAEPHRAGRQ------WKFPGSFYFAITVITTIGYGHAAPGTDSG 106
Query: 120 KAFSIAFALLGVPTTMLLLTASAQRLSLLLTHVPLS---WLSMRWGWDPRRAACWHLVAL 176
K F + +ALLG+P T++ + +RL+ ++ + L+ L +RW + +LV
Sbjct: 107 KVFCMFYALLGIPLTLVTFQSLGERLNAVVRRLLLAAKCCLGLRW----TCVSTENLVVA 162
Query: 177 LGVVVTVCFLVPAVIFAHLEEAWSFLDAFYFCFISLSTIGLGDYVPGEAPGQPYRAL-YK 235
+ + AV F+H E W+F A+Y+CFI+L+TIG GD+V ++ R L Y
Sbjct: 163 GLLACAATLALGAVAFSHF-EGWTFFHAYYYCFITLTTIGFGDFVALQSGEALQRKLPYV 221
Query: 236 VLVTVYLFLGLVAM 249
+Y+ LGL +
Sbjct: 222 AFSFLYILLGLTVI 235
>gi|16306555 potassium channel, subfamily K, member 13 [Homo
sapiens]
Length = 408
Score = 95.1 bits (235), Expect = 7e-20
Identities = 66/258 (25%), Positives = 112/258 (43%), Gaps = 36/258 (13%)
Query: 12 AAYAAYLVLGALLVARLEGPHEARLRAELETLRAQLLQRSPCVAAPALDAFVERVLAAGR 71
A YL+ GA + + LE HE + + E A R ++ L F+ A R
Sbjct: 25 ALIVLYLLGGAAVFSALELAHERQAKQRWEERLANF-SRGHNLSRDELRGFLRHYEEATR 83
Query: 72 LGRVVLANASGSANASDPAWDFASALFFASTLITTVGYGYTTPLTDAGKAFSIAFALLGV 131
G V + P WDF A +F T+++T+G+G TTP T GK F I + L+G
Sbjct: 84 AGIRV--------DNVRPRWDFTGAFYFVGTVVSTIGFGMTTPATVGGKIFLIFYGLVGC 135
Query: 132 PTTMLLLTASAQRLSLLLTHVPLSW-----------------------LSMRWGWDPRRA 168
+T+L +RL ++ ++ S + GW P
Sbjct: 136 SSTILFFNLFLERLITIIAYIMKSCHQRQLRRRGALPQESLKDAGQCEVDSLAGWKPSVY 195
Query: 169 ACWHLVALLGVVVTVCFLVPAVIFAHLEEAWSFLDAFYFCFISLSTIGLGDYVPGEAPGQ 228
++ ++++ C + ++ + E WS+ D+ YFCF++ STIG GD V +
Sbjct: 196 YVMLILCTASILISCC---ASAMYTPI-EGWSYFDSLYFCFVAFSTIGFGDLVSSQNAHY 251
Query: 229 PYRALYKVLVTVYLFLGL 246
+ LY+ V++ +G+
Sbjct: 252 ESQGLYRFANFVFILMGV 269
Score = 31.2 bits (69), Expect = 1.2
Identities = 18/58 (31%), Positives = 24/58 (41%), Gaps = 7/58 (12%)
Query: 199 WSFLDAFYFCFISLSTIGLGDYVPGEAPGQPYRALYKVLVTVYLFLGLVAMVLVLQTF 256
W F AFYF +STIG G P G K+ + Y +G + +L F
Sbjct: 95 WDFTGAFYFVGTVVSTIGFGMTTPATVGG-------KIFLIFYGLVGCSSTILFFNLF 145
>gi|32469495 potassium channel, subfamily K, member 18 [Homo
sapiens]
Length = 384
Score = 58.2 bits (139), Expect = 9e-09
Identities = 26/60 (43%), Positives = 38/60 (63%)
Query: 91 WDFASALFFASTLITTVGYGYTTPLTDAGKAFSIAFALLGVPTTMLLLTASAQRLSLLLT 150
W F S+LFF T+ +TVGYGY P+T GK + +AL G+P L+LT + L+ +L+
Sbjct: 101 WSFLSSLFFCCTVFSTVGYGYIYPVTRLGKYLCMLYALFGIPLMFLVLTDTGDILATILS 160
Score = 38.9 bits (89), Expect = 0.006
Identities = 18/46 (39%), Positives = 26/46 (56%)
Query: 176 LLGVVVTVCFLVPAVIFAHLEEAWSFLDAFYFCFISLSTIGLGDYV 221
++ ++V A I E F +AFYFCF++L+TIG GD V
Sbjct: 285 IIALIVFAYISCAAAILPFWETQLDFENAFYFCFVTLTTIGFGDTV 330
Score = 35.8 bits (81), Expect = 0.050
Identities = 21/55 (38%), Positives = 27/55 (49%), Gaps = 7/55 (12%)
Query: 199 WSFLDAFYFCFISLSTIGLGDYVPGEAPGQPYRALYKVLVTVYLFLGLVAMVLVL 253
WSFL + +FC ST+G G Y+ P L K L +Y G+ M LVL
Sbjct: 101 WSFLSSLFFCCTVFSTVGYG-YI------YPVTRLGKYLCMLYALFGIPLMFLVL 148
>gi|236462242 potassium voltage-gated channel, KQT-like subfamily,
member 5 isoform 5 [Homo sapiens]
Length = 822
Score = 42.7 bits (99), Expect = 4e-04
Identities = 19/39 (48%), Positives = 27/39 (69%)
Query: 93 FASALFFASTLITTVGYGYTTPLTDAGKAFSIAFALLGV 131
+A AL++ + +TT+GYG TPLT G+ S FALLG+
Sbjct: 298 YADALWWGTITLTTIGYGDKTPLTWLGRLLSAGFALLGI 336
>gi|236462079 potassium voltage-gated channel, KQT-like subfamily,
member 5 isoform 4 [Homo sapiens]
Length = 951
Score = 42.7 bits (99), Expect = 4e-04
Identities = 19/39 (48%), Positives = 27/39 (69%)
Query: 93 FASALFFASTLITTVGYGYTTPLTDAGKAFSIAFALLGV 131
+A AL++ + +TT+GYG TPLT G+ S FALLG+
Sbjct: 298 YADALWWGTITLTTIGYGDKTPLTWLGRLLSAGFALLGI 336
>gi|236461942 potassium voltage-gated channel, KQT-like subfamily,
member 5 isoform 3 [Homo sapiens]
Length = 942
Score = 42.7 bits (99), Expect = 4e-04
Identities = 19/39 (48%), Positives = 27/39 (69%)
Query: 93 FASALFFASTLITTVGYGYTTPLTDAGKAFSIAFALLGV 131
+A AL++ + +TT+GYG TPLT G+ S FALLG+
Sbjct: 298 YADALWWGTITLTTIGYGDKTPLTWLGRLLSAGFALLGI 336
>gi|236461719 potassium voltage-gated channel, KQT-like subfamily,
member 5 isoform 2 [Homo sapiens]
Length = 923
Score = 42.7 bits (99), Expect = 4e-04
Identities = 19/39 (48%), Positives = 27/39 (69%)
Query: 93 FASALFFASTLITTVGYGYTTPLTDAGKAFSIAFALLGV 131
+A AL++ + +TT+GYG TPLT G+ S FALLG+
Sbjct: 298 YADALWWGTITLTTIGYGDKTPLTWLGRLLSAGFALLGI 336
Database: hs.faa
Posted date: Aug 4, 2009 4:42 PM
Number of letters in database: 18,247,518
Number of sequences in database: 37,866
Lambda K H
0.325 0.138 0.425
Gapped
Lambda K H
0.267 0.0410 0.140
Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Hits to DB: 11,649,989
Number of Sequences: 37866
Number of extensions: 498456
Number of successful extensions: 1960
Number of sequences better than 10.0: 30
Number of HSP's better than 10.0 without gapping: 85
Number of HSP's successfully gapped in prelim test: 8
Number of HSP's that attempted gapping in prelim test: 1711
Number of HSP's gapped (non-prelim): 169
length of query: 313
length of database: 18,247,518
effective HSP length: 102
effective length of query: 211
effective length of database: 14,385,186
effective search space: 3035274246
effective search space used: 3035274246
T: 11
A: 40
X1: 15 ( 7.0 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 40 (21.6 bits)
S2: 62 (28.5 bits)
Search results were obtained with NCBI BLAST and RefSeq entries.
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Guide to the Human Genome
Copyright © 2010 by Stewart Scherer. All rights reserved.