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Search of human proteins with 4758216
BLASTP 2.2.11 [Jun-05-2005]
Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer,
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997),
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs", Nucleic Acids Res. 25:3389-3402.
Query= gi|4758216 dishevelled 2 [Homo sapiens]
(736 letters)
Database: hs.faa
37,866 sequences; 18,247,518 total letters
Searching..................................................done
Score E
Sequences producing significant alignments: (bits) Value
gi|4758216 dishevelled 2 [Homo sapiens] 1506 0.0
gi|41406097 dishevelled 3 [Homo sapiens] 946 0.0
gi|32479521 dishevelled 1 [Homo sapiens] 781 0.0
gi|39930479 DIX domain containing 1 isoform b [Homo sapiens] 77 6e-14
gi|83816971 DIX domain containing 1 isoform a [Homo sapiens] 77 6e-14
gi|117306167 proline-rich protein BstNI subfamily 3 precursor [H... 63 1e-09
gi|18375650 protein tyrosine phosphatase, non-receptor type 13 i... 61 3e-09
gi|18375646 protein tyrosine phosphatase, non-receptor type 13 i... 61 3e-09
gi|150417989 cyclin K isoform 1 [Homo sapiens] 60 9e-09
gi|149158690 HLA-B associated transcript-2 [Homo sapiens] 58 3e-08
gi|55750053 atrophin-1 [Homo sapiens] 57 8e-08
gi|55750041 atrophin-1 [Homo sapiens] 57 8e-08
gi|170650694 centaurin, gamma 1 isoform PIKE-L [Homo sapiens] 56 1e-07
gi|140972063 protein phosphatase 1, regulatory subunit 9B [Homo ... 56 1e-07
gi|21361831 partitioning-defective protein 3 homolog [Homo sapiens] 56 1e-07
gi|148833504 interleukin 16 isoform 2 [Homo sapiens] 56 1e-07
gi|24025688 ligand of numb-protein X 2 [Homo sapiens] 56 1e-07
gi|239751637 PREDICTED: hypothetical protein FLJ22184 [Homo sapi... 55 2e-07
gi|218156340 chapsyn-110 isoform 3 [Homo sapiens] 55 2e-07
gi|218156338 chapsyn-110 isoform 1 [Homo sapiens] 55 2e-07
gi|91199538 chapsyn-110 isoform 2 [Homo sapiens] 55 2e-07
gi|119943106 synapse-associated protein 102 isoform a [Homo sapi... 55 3e-07
gi|157388993 synaptojanin 2 binding protein [Homo sapiens] 55 3e-07
gi|87196343 PDZ domain containing 2 [Homo sapiens] 54 5e-07
gi|4557529 post-synaptic density protein 95 isoform 1 [Homo sapi... 54 7e-07
gi|90819237 myeloid/lymphoid or mixed-lineage leukemia (trithora... 54 7e-07
gi|90819233 myeloid/lymphoid or mixed-lineage leukemia (trithora... 54 7e-07
gi|90819231 myeloid/lymphoid or mixed-lineage leukemia (trithora... 54 7e-07
gi|192447426 post-synaptic density protein 95 isoform 2 [Homo sa... 54 7e-07
gi|112382257 InaD-like [Homo sapiens] 54 7e-07
>gi|4758216 dishevelled 2 [Homo sapiens]
Length = 736
Score = 1506 bits (3898), Expect = 0.0
Identities = 736/736 (100%), Positives = 736/736 (100%)
Query: 1 MAGSSTGGGGVGETKVIYHLDEEETPYLVKIPVPAERITLGDFKSVLQRPAGAKYFFKSM 60
MAGSSTGGGGVGETKVIYHLDEEETPYLVKIPVPAERITLGDFKSVLQRPAGAKYFFKSM
Sbjct: 1 MAGSSTGGGGVGETKVIYHLDEEETPYLVKIPVPAERITLGDFKSVLQRPAGAKYFFKSM 60
Query: 61 DQDFGVVKEEISDDNARLPCFNGRVVSWLVSSDNPQPEMAPPVHEPRAELAPPAPPLPPL 120
DQDFGVVKEEISDDNARLPCFNGRVVSWLVSSDNPQPEMAPPVHEPRAELAPPAPPLPPL
Sbjct: 61 DQDFGVVKEEISDDNARLPCFNGRVVSWLVSSDNPQPEMAPPVHEPRAELAPPAPPLPPL 120
Query: 121 PPERTSGIGDSRPPSFHPNVSSSHENLEPETETESVVSLRRERPRRRDSSEHGAGGHRTG 180
PPERTSGIGDSRPPSFHPNVSSSHENLEPETETESVVSLRRERPRRRDSSEHGAGGHRTG
Sbjct: 121 PPERTSGIGDSRPPSFHPNVSSSHENLEPETETESVVSLRRERPRRRDSSEHGAGGHRTG 180
Query: 181 GPSRLERHLAGYESSSTLMTSELESTSLGDSDEEDTMSRFSSSTEQSSASRLLKRHRRRR 240
GPSRLERHLAGYESSSTLMTSELESTSLGDSDEEDTMSRFSSSTEQSSASRLLKRHRRRR
Sbjct: 181 GPSRLERHLAGYESSSTLMTSELESTSLGDSDEEDTMSRFSSSTEQSSASRLLKRHRRRR 240
Query: 241 KQRPPRLERTSSFSSVTDSTMSLNIITVTLNMEKYNFLGISIVGQSNERGDGGIYIGSIM 300
KQRPPRLERTSSFSSVTDSTMSLNIITVTLNMEKYNFLGISIVGQSNERGDGGIYIGSIM
Sbjct: 241 KQRPPRLERTSSFSSVTDSTMSLNIITVTLNMEKYNFLGISIVGQSNERGDGGIYIGSIM 300
Query: 301 KGGAVAADGRIEPGDMLLQVNDMNFENMSNDDAVRVLRDIVHKPGPIVLTVAKCWDPSPQ 360
KGGAVAADGRIEPGDMLLQVNDMNFENMSNDDAVRVLRDIVHKPGPIVLTVAKCWDPSPQ
Sbjct: 301 KGGAVAADGRIEPGDMLLQVNDMNFENMSNDDAVRVLRDIVHKPGPIVLTVAKCWDPSPQ 360
Query: 361 AYFTLPRNEPIQPIDPAAWVSHSAALTGTFPAYPGSSSMSTITSGSSLPDGCEGRGLSVH 420
AYFTLPRNEPIQPIDPAAWVSHSAALTGTFPAYPGSSSMSTITSGSSLPDGCEGRGLSVH
Sbjct: 361 AYFTLPRNEPIQPIDPAAWVSHSAALTGTFPAYPGSSSMSTITSGSSLPDGCEGRGLSVH 420
Query: 421 TDMASVTKAMAAPESGLEVRDRMWLKITIPNAFLGSDVVDWLYHHVEGFPERREARKYAS 480
TDMASVTKAMAAPESGLEVRDRMWLKITIPNAFLGSDVVDWLYHHVEGFPERREARKYAS
Sbjct: 421 TDMASVTKAMAAPESGLEVRDRMWLKITIPNAFLGSDVVDWLYHHVEGFPERREARKYAS 480
Query: 481 GLLKAGLIRHTVNKITFSEQCYYVFGDLSGGCESYLVNLSLNDNDGSSGASDQDTLAPLP 540
GLLKAGLIRHTVNKITFSEQCYYVFGDLSGGCESYLVNLSLNDNDGSSGASDQDTLAPLP
Sbjct: 481 GLLKAGLIRHTVNKITFSEQCYYVFGDLSGGCESYLVNLSLNDNDGSSGASDQDTLAPLP 540
Query: 541 GATPWPLLPTFSYQYPAPHPYSPQPPPYHELSSYTYGGGSASSQHSEGSRSSGSTRSDGG 600
GATPWPLLPTFSYQYPAPHPYSPQPPPYHELSSYTYGGGSASSQHSEGSRSSGSTRSDGG
Sbjct: 541 GATPWPLLPTFSYQYPAPHPYSPQPPPYHELSSYTYGGGSASSQHSEGSRSSGSTRSDGG 600
Query: 601 AGRTGRPEERAPESKSGSGSESEPSSRGGSLRRGGEASGTSDGGPPPSRGSTGGAPNLRA 660
AGRTGRPEERAPESKSGSGSESEPSSRGGSLRRGGEASGTSDGGPPPSRGSTGGAPNLRA
Sbjct: 601 AGRTGRPEERAPESKSGSGSESEPSSRGGSLRRGGEASGTSDGGPPPSRGSTGGAPNLRA 660
Query: 661 HPGLHPYGPPPGMALPYNPMMVVMMPPPPPPVPPAVQPPGAPPVRDLGSVPPELTASRQS 720
HPGLHPYGPPPGMALPYNPMMVVMMPPPPPPVPPAVQPPGAPPVRDLGSVPPELTASRQS
Sbjct: 661 HPGLHPYGPPPGMALPYNPMMVVMMPPPPPPVPPAVQPPGAPPVRDLGSVPPELTASRQS 720
Query: 721 FHMAMGNPSEFFVDVM 736
FHMAMGNPSEFFVDVM
Sbjct: 721 FHMAMGNPSEFFVDVM 736
>gi|41406097 dishevelled 3 [Homo sapiens]
Length = 716
Score = 946 bits (2446), Expect = 0.0
Identities = 515/743 (69%), Positives = 588/743 (79%), Gaps = 44/743 (5%)
Query: 11 VGETKVIYHLDEEETPYLVKIPVPAERITLGDFKSVLQRPAGAKYFFKSMDQDFGVVKEE 70
+GETK+IYHLD +ETPYLVK+P+PAER+TL DFK VLQRP+ K+FFKSMD DFGVVKEE
Sbjct: 1 MGETKIIYHLDGQETPYLVKLPLPAERVTLADFKGVLQRPS-YKFFFKSMDDDFGVVKEE 59
Query: 71 ISDDNARLPCFNGRVVSWLVSSDNPQPEMAPPVHEPRAELAPPAPPLPPLPPERTSGIGD 130
ISDDNA+LPCFNGRVVSWLVS++ P+ AP + +EL PP ERT GIGD
Sbjct: 60 ISDDNAKLPCFNGRVVSWLVSAEGSHPDPAPFCADNPSELPPPM--------ERTGGIGD 111
Query: 131 SRPPSFHPNVSS-SHENLEPETETESVVSLRRERPRRRDSSEHGAGGHRTGGPSRLERHL 189
SRPPSFHP+ S ENL+ +TET+S+VS +RERPRRRD EH + T R R
Sbjct: 112 SRPPSFHPHAGGGSQENLDNDTETDSLVSAQRERPRRRDGPEHATRLNGTAKGER-RREP 170
Query: 190 AGYESSSTLMTSELESTSLGDSDEEDTMSRFSSSTEQSSASRLLKRH-RRRRKQRPPRLE 248
GY+SSSTLM+SELE+TS DSDE+D+ SRFSSSTEQSSASRL++RH RRRRKQ+ R+E
Sbjct: 171 GGYDSSSTLMSSELETTSFFDSDEDDSTSRFSSSTEQSSASRLMRRHKRRRRKQKVSRIE 230
Query: 249 RTSSFSSVTDSTMSLNIITVTLNMEKYNFLGISIVGQSNERGDGGIYIGSIMKGGAVAAD 308
R+SSFSS+TDSTMSLNIITVTLNMEKYNFLGISIVGQSNERGDGGIYIGSIMKGGAVAAD
Sbjct: 231 RSSSFSSITDSTMSLNIITVTLNMEKYNFLGISIVGQSNERGDGGIYIGSIMKGGAVAAD 290
Query: 309 GRIEPGDMLLQVNDMNFENMSNDDAVRVLRDIVHKPGPIVLTVAKCWDPSPQAYFTLPRN 368
GRIEPGDMLLQVN++NFENMSNDDAVRVLR+IVHKPGPI LTVAKCWDPSP+ FTLPR+
Sbjct: 291 GRIEPGDMLLQVNEINFENMSNDDAVRVLREIVHKPGPITLTVAKCWDPSPRGCFTLPRS 350
Query: 369 EPIQPIDPAAWVSHSAALTGTFPAYPGSSSMSTITS-----GSSLPD--GCEGRGLSVHT 421
EPI+PIDPAAWVSH+AA+TGTFPAY S S+STITS SS+PD + LS+H+
Sbjct: 351 EPIRPIDPAAWVSHTAAMTGTFPAYGMSPSLSTITSTSSSITSSIPDTERLDDFHLSIHS 410
Query: 422 DMASVTKAMAAPESGLEVRDRMWLKITIPNAFLGSDVVDWLYHHVEGFPERREARKYASG 481
DMA++ KAMA+PESGLEVRDRMWLKITIPNAF+GSDVVDWLYH+VEGF +RREARKYAS
Sbjct: 411 DMAAIVKAMASPESGLEVRDRMWLKITIPNAFIGSDVVDWLYHNVEGFTDRREARKYASN 470
Query: 482 LLKAGLIRHTVNKITFSEQCYYVFGDLSGGCESYLVNLSLNDNDGSSGASDQDTLAPL-- 539
LLKAG IRHTVNKITFSEQCYY+FGDL G + NLSL+D+DGSSGASDQDTLAPL
Sbjct: 471 LLKAGFIRHTVNKITFSEQCYYIFGDLCGN----MANLSLHDHDGSSGASDQDTLAPLPH 526
Query: 540 PGATPWPLLPTFSYQY-PAPHPYSPQPPPYHELSSYTYGGGSASSQHSEGSRSSGSTRSD 598
PGA PWP+ F YQY P PHPY+P P + EL Y+YGGGSASSQHSEGSRSSGS RS
Sbjct: 527 PGAAPWPM--AFPYQYPPPPHPYNPH-PGFPEL-GYSYGGGSASSQHSEGSRSSGSNRS- 581
Query: 599 GGAGRTGRPEERAPESKS-GSGSESEPSSRGGSLRRGGEASGTSDGGPPPS----RGSTG 653
G+ R + +A +SKS GSGSES+ ++R SLR E + + GP S R
Sbjct: 582 -GSDRRKEKDPKAGDSKSGGSGSESDHTTR-SSLRGPRERAPSERSGPAASEHSHRSHHS 639
Query: 654 GAPNLRAHPGLHPYGPPPGMALPYNPMMVVMMPPPPPPVPPAVQPPGAPPVRDLGSVPPE 713
A +LR+H HP PPG+ Y P M +MMPPP P A+ PPGAPP RDL SVPPE
Sbjct: 640 LASSLRSH-HTHPSYGPPGVPPLYGPPM-LMMPPP----PAAMGPPGAPPGRDLASVPPE 693
Query: 714 LTASRQSFHMAMGNPSEFFVDVM 736
LTASRQSF MAMGNPSEFFVDVM
Sbjct: 694 LTASRQSFRMAMGNPSEFFVDVM 716
>gi|32479521 dishevelled 1 [Homo sapiens]
Length = 670
Score = 781 bits (2017), Expect = 0.0
Identities = 431/737 (58%), Positives = 508/737 (68%), Gaps = 78/737 (10%)
Query: 11 VGETKVIYHLDEEETPYLVKIPVPAERITLGDFKSVLQ-RPAGA-KYFFKSMDQDFGVVK 68
+ ETK+IYH+DEEETPYLVK+PV ER+TL DFK+VL RP A K+FFKSMDQDFGVVK
Sbjct: 1 MAETKIIYHMDEEETPYLVKLPVAPERVTLADFKNVLSNRPVHAYKFFFKSMDQDFGVVK 60
Query: 69 EEISDDNARLPCFNGRVVSWLVSSDNPQPEMAPPVHEPRAELAPPAPPLPPLPPERTSGI 128
EEI DDNA+LPCFNGRVVSWLV ++ + + +L PP ERT GI
Sbjct: 61 EEIFDDNAKLPCFNGRVVSWLVLAEGAHSDAGSQGTDSHTDLPPPL--------ERTGGI 112
Query: 129 GDSRPPSFHPNVSSSHENLEPETETESVVSLRRERPRRRDSSEHGAGGHRTGGPSRLERH 188
GDSRPPSFHPNV+SS + ++ ET TES+VS RRER RRR+ E G R +
Sbjct: 113 GDSRPPSFHPNVASSRDGMDNETGTESMVSHRRERARRRNREEAARTNGHPRGDRRRDVG 172
Query: 189 LAGYESSSTLMTSELESTSLGDSDEEDTMSRFSSSTEQSSASRLLKRH-RRRRKQRPPRL 247
L +S+ST ++SELES+S DSDE+ + SR SSSTEQS++SRL+++H RRRRKQR +
Sbjct: 173 LPP-DSASTALSSELESSSFVDSDEDGSTSRLSSSTEQSTSSRLIRKHKRRRRKQRLRQA 231
Query: 248 ERTSSFSSVTDSTMSLNIITVTLNMEKYNFLGISIVGQSNERGDGGIYIGSIMKGGAVAA 307
+R SSFSS+TDSTMSLNI+TVTLNME+++FLGISIVGQSN+RGDGGIYIGSIMKGGAVAA
Sbjct: 232 DRASSFSSITDSTMSLNIVTVTLNMERHHFLGISIVGQSNDRGDGGIYIGSIMKGGAVAA 291
Query: 308 DGRIEPGDMLLQVNDMNFENMSNDDAVRVLRDIVHKPGPIVLTVAKCWDPSPQAYFTLPR 367
DGRIEPGDMLLQVND+NFENMSNDDAVRVLR+IV + GPI LTVAKCWDP+P++YFT+PR
Sbjct: 292 DGRIEPGDMLLQVNDVNFENMSNDDAVRVLREIVSQTGPISLTVAKCWDPTPRSYFTVPR 351
Query: 368 NEPIQPIDPAAWVSHSAALTGTFPAYPGSSSMSTITSGSSLPDGCEGRGLSVHTDMASVT 427
+P++PIDPAAW+SH+AALTG P Y E L+V +DM++V
Sbjct: 352 ADPVRPIDPAAWLSHTAALTGALPRYE-----------------LEEAPLTVKSDMSAVV 394
Query: 428 KAMAAPESGLEVRDRMWLKITIPNAFLGSDVVDWLYHHVEGFPERREARKYASGLLKAGL 487
+ M P+SGLE+RDRMWLKITI NA +G+DVVDWLY HVEGF ERREARKYAS LLK G
Sbjct: 395 RVMQLPDSGLEIRDRMWLKITIANAVIGADVVDWLYTHVEGFKERREARKYASSLLKHGF 454
Query: 488 IRHTVNKITFSEQCYYVFGDLSGGCESYLVNLSLNDNDGSSGASDQDTLAPLP-GATPWP 546
+RHTVNKITFSEQCYYVFGDL +LN N GSSG SDQDTLAPLP A PWP
Sbjct: 455 LRHTVNKITFSEQCYYVFGDLCSNL------ATLNLNSGSSGTSDQDTLAPLPHPAAPWP 508
Query: 547 LLPTFSYQYPAPHPYSPQPPPYHELSSYTYGGGSASSQHSEGSRSSGSTRSDGGAGRTGR 606
L + YQYP P P PP ++ ++YG GS SQ SEGS+SSGSTRS A GR
Sbjct: 509 LGQGYPYQYPGPPPCF---PPAYQDPGFSYGSGSTGSQQSEGSKSSGSTRSSRRA--PGR 563
Query: 607 PEERAPESKSGSGSESE---PSSRGGSLRRGGEASGTSDGGPPPSRGSTGGAPNLRAHPG 663
+ER GSGSES+ PS G S R +G G P ++ AP L
Sbjct: 564 EKERRAAGAGGSGSESDHTAPSGVGSSWRE--RPAGQLSRGSSPRSQASATAPGL----- 616
Query: 664 LHPYGPPPGMALPYNPMMVVMMPPPPPPVPPAVQ----PPGAPPVRDLGSVPPELTASRQ 719
PPP P A PPG PPVR+L +VPPELT SRQ
Sbjct: 617 -----------------------PPPHPTTKAYTVVGGPPGGPPVRELAAVPPELTGSRQ 653
Query: 720 SFHMAMGNPSEFFVDVM 736
SF AMGNP EFFVD+M
Sbjct: 654 SFQKAMGNPCEFFVDIM 670
>gi|39930479 DIX domain containing 1 isoform b [Homo sapiens]
Length = 472
Score = 77.0 bits (188), Expect = 6e-14
Identities = 33/76 (43%), Positives = 50/76 (65%)
Query: 14 TKVIYHLDEEETPYLVKIPVPAERITLGDFKSVLQRPAGAKYFFKSMDQDFGVVKEEISD 73
TKV+Y D TP++V IP E +TL DFK+ + R +Y FK++D +FG VKEEI
Sbjct: 390 TKVLYFTDRSLTPFMVNIPKRLEEVTLKDFKAAIDREGNHRYHFKALDPEFGTVKEEIFH 449
Query: 74 DNARLPCFNGRVVSWL 89
D+ +P + G++V+W+
Sbjct: 450 DDDAIPGWEGKIVAWV 465
>gi|83816971 DIX domain containing 1 isoform a [Homo sapiens]
Length = 683
Score = 77.0 bits (188), Expect = 6e-14
Identities = 33/76 (43%), Positives = 50/76 (65%)
Query: 14 TKVIYHLDEEETPYLVKIPVPAERITLGDFKSVLQRPAGAKYFFKSMDQDFGVVKEEISD 73
TKV+Y D TP++V IP E +TL DFK+ + R +Y FK++D +FG VKEEI
Sbjct: 601 TKVLYFTDRSLTPFMVNIPKRLEEVTLKDFKAAIDREGNHRYHFKALDPEFGTVKEEIFH 660
Query: 74 DNARLPCFNGRVVSWL 89
D+ +P + G++V+W+
Sbjct: 661 DDDAIPGWEGKIVAWV 676
>gi|117306167 proline-rich protein BstNI subfamily 3 precursor [Homo
sapiens]
Length = 309
Score = 62.8 bits (151), Expect = 1e-09
Identities = 49/162 (30%), Positives = 60/162 (37%), Gaps = 23/162 (14%)
Query: 554 QYPAPHPYSPQPPPYHELSSYTYGGGSASSQ-----HSEGSRSSGSTRSDGGAGRTGRPE 608
Q P P P P+ PP GG + EG G +S G R G+PE
Sbjct: 153 QGPPPRPGKPEGPP-------PQGGNQSQGPPPHPGKPEGPPPQGGNQSQGPPPRPGKPE 205
Query: 609 ERAPESKSGS-------GSESEPSSRGGSLRRGGEASGTSDGGPPPSRGSTGGAPNLRAH 661
P+ + S G P S+GG+ +G GPPP G+ P
Sbjct: 206 GPPPQGGNQSQGPPPRPGKPEGPPSQGGNKPQGPPPHPGKPQGPPPQEGNK---PQRPPP 262
Query: 662 PGLHPYGPPPGMALPYNPMMVVMMPPPPPPVPPAVQPPGAPP 703
PG P GPPP P P+ P PP PP P PP
Sbjct: 263 PG-RPQGPPPPGGNPQQPLPPPAGKPQGPPPPPQGGRPHRPP 303
Score = 60.8 bits (146), Expect = 4e-09
Identities = 48/162 (29%), Positives = 55/162 (33%), Gaps = 21/162 (12%)
Query: 554 QYPAPHPYSPQPPPYHELSSYTYGGGSASSQ-----HSEGSRSSGSTRSDGGAGRTGRPE 608
Q P P P P+ PP GG + EG G +S G G+PE
Sbjct: 132 QGPPPRPGKPEGPP-------PQGGNQSQGPPPRPGKPEGPPPQGGNQSQGPPPHPGKPE 184
Query: 609 ERAPESKSGSGSESEPSSRGGSLRRGGEASGTSDGGPPPSRGSTGGAPNLRAHPGLHPYG 668
P+ G P R G G GPPP G G P+ G P G
Sbjct: 185 GPPPQ---GGNQSQGPPPRPGKPEGPPPQGGNQSQGPPPRPGKPEGPPS---QGGNKPQG 238
Query: 669 PPPGMALPYNPMMV---VMMPPPPPPVPPAVQPPGAPPVRDL 707
PPP P P PPPP P PPG P + L
Sbjct: 239 PPPHPGKPQGPPPQEGNKPQRPPPPGRPQGPPPPGGNPQQPL 280
Score = 51.6 bits (122), Expect = 3e-06
Identities = 47/168 (27%), Positives = 52/168 (30%), Gaps = 21/168 (12%)
Query: 560 PYSPQPPPYHELSSYTYGGGSASSQ-----HSEGSRSSGSTRSDGGAGRTGRPEERAPES 614
P PPP GG + EG G +S G R G+PE + P+
Sbjct: 47 PQRTPPPPGKPEGRPPQGGNQSQGPPPRPGKPEGPPPQGGNQSQGPPPRPGKPEGQPPQ- 105
Query: 615 KSGSGSESEPSSRGGSLRRGGEASGTSDGGPPPSRGSTGGAPNLRAHPGLHPYGPPPGMA 674
G P R G G GPPP G G P G GPPP
Sbjct: 106 --GGNQSQGPPPRPGKPEGPPPQGGNQSQGPPPRPGKPEGPP---PQGGNQSQGPPPRPG 160
Query: 675 LPYNPMMV---VMMPPPPPPVPPAVQPP-------GAPPVRDLGSVPP 712
P P PPP P P PP G PP PP
Sbjct: 161 KPEGPPPQGGNQSQGPPPHPGKPEGPPPQGGNQSQGPPPRPGKPEGPP 208
Score = 47.4 bits (111), Expect = 5e-05
Identities = 42/143 (29%), Positives = 45/143 (31%), Gaps = 16/143 (11%)
Query: 580 SASSQHSEGSRSSGSTRSDGGAGRTGRPEERAPESKSGSGSESEPSSRGGSLRRGGEASG 639
S S EG R G + G+PE R P+ G P R G G
Sbjct: 30 SVISGKPEGRRPQGGNQPQRTPPPPGKPEGRPPQ---GGNQSQGPPPRPGKPEGPPPQGG 86
Query: 640 TSDGGPPPSRGSTGGAPNLRAHPGLHPYGPPPGMALPYNPMMV---VMMPPPPPPVPPAV 696
GPPP G G P G GPPP P P PPP P P
Sbjct: 87 NQSQGPPPRPGKPEGQP---PQGGNQSQGPPPRPGKPEGPPPQGGNQSQGPPPRPGKPEG 143
Query: 697 QPP-------GAPPVRDLGSVPP 712
PP G PP PP
Sbjct: 144 PPPQGGNQSQGPPPRPGKPEGPP 166
>gi|18375650 protein tyrosine phosphatase, non-receptor type 13
isoform 4 [Homo sapiens]
Length = 2490
Score = 61.2 bits (147), Expect = 3e-09
Identities = 72/334 (21%), Positives = 140/334 (41%), Gaps = 32/334 (9%)
Query: 121 PPERTSGIGDSRPPSFHPNVSSSHENLEPETETESVVSLRRERPRRRDSSEHGAGGHRTG 180
P E + D S +P+ + N+EP +T + + + R +E AG +
Sbjct: 963 PREMSKSYHDLSQASLYPHRKNVIVNMEPPPQTVAELVGKPSHQMSRSDAESLAGVTKLN 1022
Query: 181 GPSRLERHLAGYESSSTLMTSELESTSLGDSDEEDTMSRFSSSTEQSSASRLLKRHRRRR 240
+ +A S E +S+S+ D + + S+ SS+ LK +
Sbjct: 1023 N----SKSVASLNRSPERRKHESDSSSIEDPGQAYVLGMTMHSSGNSSSQVPLKENDVLH 1078
Query: 241 KQRPPRLERTSSFSSVTDSTMSLNIITVTLNMEKYNFLGISIVG-QSNERGDGGIYIGSI 299
K+ +S V+ + ++ + + KY LG I+G + R D GI+I S+
Sbjct: 1079 KR----------WSIVSSPEREITLVNLKKDA-KYG-LGFQIIGGEKMGRLDLGIFISSV 1126
Query: 300 MKGGAVAADGRIEPGDMLLQVNDMNFENMSNDDAVRVLRDIVHKPGPIVLTVAKCWD--- 356
GG DG ++PGD L+ VN ++ E +S+ A+ +L+ + P + L +++ +
Sbjct: 1127 APGGPADLDGCLKPGDRLISVNSVSLEGVSHHAAIEILQ---NAPEDVTLVISQPKEKIS 1183
Query: 357 --PSPQAYFTLPRNEPIQPIDPAAWVSHSAALTGTFPAYPGSSSMSTITSGSSLPDGCEG 414
PS + T NE + ++++ SA + + + ++ I+ S P G
Sbjct: 1184 KVPSTPVHLT---NEMKNYMKKSSYMQDSAIDSSSKDHHWSRGTLRHISENSFGPSGGLR 1240
Query: 415 RG----LSVHTDMASVTKAMAAPESGLEVRDRMW 444
G T+ AS++++ + D+ W
Sbjct: 1241 EGSLSSQDSRTESASLSQSQVNGFFASHLGDQTW 1274
Score = 52.0 bits (123), Expect = 2e-06
Identities = 68/285 (23%), Positives = 113/285 (39%), Gaps = 58/285 (20%)
Query: 95 PQPEMAPPVHEPRAELAPPAPPLPPLPPERTSGIGDSRPPSFHPNVSSSHENLEPETETE 154
P P + P + A L P P LP + DS PS +SS EN + +
Sbjct: 1593 PPPGVLPEIDT--ALLTPLQSPAQVLP----NSSKDSSQPSCVEQSTSSDENEMSDKSKK 1646
Query: 155 SVVSLRRERPRRRDSSEHGAGGHRTG---GPSRLERHLAGYESSSTL--MTSELESTSLG 209
S P RRDS +G P+ + TL M S+ +S
Sbjct: 1647 QCKS-----PSRRDSYSDSSGSGEDDLVTAPANISNSTWSSALHQTLSNMVSQAQSHHEA 1701
Query: 210 DSDEEDTM-------------------------------SRFSSSTEQSSASRLLKRHRR 238
+EDT+ + +E +S+S + K H
Sbjct: 1702 PKSQEDTICTMFYYPQKIPNKPEFEDSNPSPLPPDMAPGQSYQPQSESASSSSMDKYHIH 1761
Query: 239 RRKQRPPRLERTSSFSS-----VTDSTMSLNIITVTLNMEKYNFLGISIVGQSNERGDGG 293
+ P R E + + + D + + ++ + EK + LG ++ + N+R G
Sbjct: 1762 HISE-PTRQENWTPLKNDLENHLEDFELEVELLITLIKSEKGS-LGFTVT-KGNQRI--G 1816
Query: 294 IYIGSIMKGGAVAADGRIEPGDMLLQVNDMNFENMSNDDAVRVLR 338
Y+ +++ A +DGR++PGD L++VND + NM++ DAV +LR
Sbjct: 1817 CYVHDVIQDPA-KSDGRLKPGDRLIKVNDTDVTNMTHTDAVNLLR 1860
Score = 49.3 bits (116), Expect = 1e-05
Identities = 46/178 (25%), Positives = 79/178 (44%), Gaps = 17/178 (9%)
Query: 177 HRTGGPSRLERHLAGYESSSTLMTSELESTSLGDSDEEDTMSRFSSSTEQSSASRLLKRH 236
H + PS + + E + +++ ++ G SD D R S ++++ S +
Sbjct: 1279 HGSPSPSVISK---ATEKETFTDSNQSKTKKPGISDVTDYSDRGDSDMDEATYSS--SQD 1333
Query: 237 RRRRKQRPPRLERTSS---FSSVTDSTMSLNIITVTLNMEKYNFLGISIV------GQSN 287
+ KQ TS+ F + + S I + N LGIS+ G +
Sbjct: 1334 HQTPKQESSSSVNTSNKMNFKTFSSSPPKPGDIFEVELAKNDNSLGISVTVLFDKGGVNT 1393
Query: 288 ERGDGGIYIGSIMKGGAVAADGRIEPGDMLLQVNDMNFENMSNDDAVRVLRD---IVH 342
GGIY+ +++ GA +DGRI GD +L VN ++ E ++ AV LR+ +VH
Sbjct: 1394 SVRHGGIYVKAVIPQGAAESDGRIHKGDRVLAVNGVSLEGATHKQAVETLRNTGQVVH 1451
Score = 32.0 bits (71), Expect = 2.1
Identities = 27/104 (25%), Positives = 51/104 (49%), Gaps = 12/104 (11%)
Query: 242 QRPPRLERTSS---FSSVTDSTMSLNIITVTLNMEKYNFLGISIVGQSN---ERGDGGIY 295
Q P ++++T+ +S VT+ N V L + + LG S + N E+ + I
Sbjct: 1482 QGPEKVKKTTQVKDYSFVTEE----NTFEVKL-FKNSSGLGFSFSREDNLIPEQINASIV 1536
Query: 296 -IGSIMKGGAVAADGRIEPGDMLLQVNDMNFENMSNDDAVRVLR 338
+ + G A G+I+ GD++L+VN + + +S + + LR
Sbjct: 1537 RVKKLFPGQPAAESGKIDVGDVILKVNGASLKGLSQQEVISALR 1580
>gi|18375646 protein tyrosine phosphatase, non-receptor type 13
isoform 1 [Homo sapiens]
Length = 2485
Score = 61.2 bits (147), Expect = 3e-09
Identities = 72/334 (21%), Positives = 140/334 (41%), Gaps = 32/334 (9%)
Query: 121 PPERTSGIGDSRPPSFHPNVSSSHENLEPETETESVVSLRRERPRRRDSSEHGAGGHRTG 180
P E + D S +P+ + N+EP +T + + + R +E AG +
Sbjct: 963 PREMSKSYHDLSQASLYPHRKNVIVNMEPPPQTVAELVGKPSHQMSRSDAESLAGVTKLN 1022
Query: 181 GPSRLERHLAGYESSSTLMTSELESTSLGDSDEEDTMSRFSSSTEQSSASRLLKRHRRRR 240
+ +A S E +S+S+ D + + S+ SS+ LK +
Sbjct: 1023 N----SKSVASLNRSPERRKHESDSSSIEDPGQAYVLGMTMHSSGNSSSQVPLKENDVLH 1078
Query: 241 KQRPPRLERTSSFSSVTDSTMSLNIITVTLNMEKYNFLGISIVG-QSNERGDGGIYIGSI 299
K+ +S V+ + ++ + + KY LG I+G + R D GI+I S+
Sbjct: 1079 KR----------WSIVSSPEREITLVNLKKDA-KYG-LGFQIIGGEKMGRLDLGIFISSV 1126
Query: 300 MKGGAVAADGRIEPGDMLLQVNDMNFENMSNDDAVRVLRDIVHKPGPIVLTVAKCWD--- 356
GG DG ++PGD L+ VN ++ E +S+ A+ +L+ + P + L +++ +
Sbjct: 1127 APGGPADLDGCLKPGDRLISVNSVSLEGVSHHAAIEILQ---NAPEDVTLVISQPKEKIS 1183
Query: 357 --PSPQAYFTLPRNEPIQPIDPAAWVSHSAALTGTFPAYPGSSSMSTITSGSSLPDGCEG 414
PS + T NE + ++++ SA + + + ++ I+ S P G
Sbjct: 1184 KVPSTPVHLT---NEMKNYMKKSSYMQDSAIDSSSKDHHWSRGTLRHISENSFGPSGGLR 1240
Query: 415 RG----LSVHTDMASVTKAMAAPESGLEVRDRMW 444
G T+ AS++++ + D+ W
Sbjct: 1241 EGSLSSQDSRTESASLSQSQVNGFFASHLGDQTW 1274
Score = 52.8 bits (125), Expect = 1e-06
Identities = 47/173 (27%), Positives = 79/173 (45%), Gaps = 12/173 (6%)
Query: 177 HRTGGPSRLERHLAGYESSSTLMTSELESTSLGDSDEEDTMSRFSSSTEQSSASRLLKRH 236
H + PS + + E + +++ ++ G SD D R S ++++ S +
Sbjct: 1279 HGSPSPSVISK---ATEKETFTDSNQSKTKKPGISDVTDYSDRGDSDMDEATYSS--SQD 1333
Query: 237 RRRRKQRPPRLERTSS---FSSVTDSTMSLNIITVTLNMEKYNFLGISIVGQSNER-GDG 292
+ KQ TS+ F + + S I + N LGIS+ G N G
Sbjct: 1334 HQTPKQESSSSVNTSNKMNFKTFSSSPPKPGDIFEVELAKNDNSLGISVTGGVNTSVRHG 1393
Query: 293 GIYIGSIMKGGAVAADGRIEPGDMLLQVNDMNFENMSNDDAVRVLRD---IVH 342
GIY+ +++ GA +DGRI GD +L VN ++ E ++ AV LR+ +VH
Sbjct: 1394 GIYVKAVIPQGAAESDGRIHKGDRVLAVNGVSLEGATHKQAVETLRNTGQVVH 1446
Score = 52.0 bits (123), Expect = 2e-06
Identities = 68/285 (23%), Positives = 113/285 (39%), Gaps = 58/285 (20%)
Query: 95 PQPEMAPPVHEPRAELAPPAPPLPPLPPERTSGIGDSRPPSFHPNVSSSHENLEPETETE 154
P P + P + A L P P LP + DS PS +SS EN + +
Sbjct: 1588 PPPGVLPEIDT--ALLTPLQSPAQVLP----NSSKDSSQPSCVEQSTSSDENEMSDKSKK 1641
Query: 155 SVVSLRRERPRRRDSSEHGAGGHRTG---GPSRLERHLAGYESSSTL--MTSELESTSLG 209
S P RRDS +G P+ + TL M S+ +S
Sbjct: 1642 QCKS-----PSRRDSYSDSSGSGEDDLVTAPANISNSTWSSALHQTLSNMVSQAQSHHEA 1696
Query: 210 DSDEEDTM-------------------------------SRFSSSTEQSSASRLLKRHRR 238
+EDT+ + +E +S+S + K H
Sbjct: 1697 PKSQEDTICTMFYYPQKIPNKPEFEDSNPSPLPPDMAPGQSYQPQSESASSSSMDKYHIH 1756
Query: 239 RRKQRPPRLERTSSFSS-----VTDSTMSLNIITVTLNMEKYNFLGISIVGQSNERGDGG 293
+ P R E + + + D + + ++ + EK + LG ++ + N+R G
Sbjct: 1757 HISE-PTRQENWTPLKNDLENHLEDFELEVELLITLIKSEKGS-LGFTVT-KGNQRI--G 1811
Query: 294 IYIGSIMKGGAVAADGRIEPGDMLLQVNDMNFENMSNDDAVRVLR 338
Y+ +++ A +DGR++PGD L++VND + NM++ DAV +LR
Sbjct: 1812 CYVHDVIQDPA-KSDGRLKPGDRLIKVNDTDVTNMTHTDAVNLLR 1855
Score = 32.0 bits (71), Expect = 2.1
Identities = 27/104 (25%), Positives = 51/104 (49%), Gaps = 12/104 (11%)
Query: 242 QRPPRLERTSS---FSSVTDSTMSLNIITVTLNMEKYNFLGISIVGQSN---ERGDGGIY 295
Q P ++++T+ +S VT+ N V L + + LG S + N E+ + I
Sbjct: 1477 QGPEKVKKTTQVKDYSFVTEE----NTFEVKL-FKNSSGLGFSFSREDNLIPEQINASIV 1531
Query: 296 -IGSIMKGGAVAADGRIEPGDMLLQVNDMNFENMSNDDAVRVLR 338
+ + G A G+I+ GD++L+VN + + +S + + LR
Sbjct: 1532 RVKKLFPGQPAAESGKIDVGDVILKVNGASLKGLSQQEVISALR 1575
>gi|150417989 cyclin K isoform 1 [Homo sapiens]
Length = 580
Score = 59.7 bits (143), Expect = 9e-09
Identities = 60/195 (30%), Positives = 73/195 (37%), Gaps = 21/195 (10%)
Query: 526 GSSGASDQDTLAPLPGATPWPLLPTFSYQYPAPHPYSPQPPPYHELSSYTYGGGSASSQH 585
G A+D + P A P P+ P P P+ P PPP SSY G + SS
Sbjct: 389 GPVDATDLPKVQIPPPAHPAPV------HQPPPLPHRPPPPPP---SSYMTGMSTTSSYM 439
Query: 586 S-EGSRSSGSTRSDGGAGRTGRPEERAPESKSGSGSESEPSSRGGSLRRGGEASGTSDGG 644
S EG +S S G P P + P + AS
Sbjct: 440 SGEGYQSLQSMMKTEGPSYGALPPAYGPPAHLPYHPHVYPPNPPPPPVPPPPASFPPPAI 499
Query: 645 PPPSRGSTGGAPNLRAH--------PGLH--PYGPPPGMALPYNPMMVVMMPPP-PPPVP 693
PPP+ G P + P H P PPPG+ LP +PP PPVP
Sbjct: 500 PPPTPGYPPPPPTYNPNFPPPPPRLPPTHAVPPHPPPGLGLPPASYPPPAVPPGGQPPVP 559
Query: 694 PAVQPPGAPPVRDLG 708
P + PPG PPV LG
Sbjct: 560 PPIPPPGMPPVGGLG 574
Score = 34.7 bits (78), Expect = 0.33
Identities = 42/164 (25%), Positives = 57/164 (34%), Gaps = 25/164 (15%)
Query: 554 QYPAPHPYSPQPPPYHELSSYTYGGGSASSQHSEGSRSSGSTRSDGGAGRTGRPEERAPE 613
Q P P+ Q PP L SQ S+ S S + D + + ++ A +
Sbjct: 264 QMPHHTPHQLQQPP--SLQPTPQVPQVQQSQPSQSSEPSQPQQKD--PQQPAQQQQPAQQ 319
Query: 614 SKSGSGSESEPSSRGGSLRRGGEASGTSDGGPPPSRGSTGGAPNLRA-HPGLHPYGPPP- 671
K S S P ++ + + PPP P + HP L P PPP
Sbjct: 320 PKKPSPQPSSPRQVKRAVVVSPKEENKAAEPPPPK------IPKIETTHPPLPPAHPPPD 373
Query: 672 ---------GMALPYNPMMVVMMP----PPPPPVPPAVQPPGAP 702
G A P P+ +P PPP P QPP P
Sbjct: 374 RKPPLAAALGEAEPPGPVDATDLPKVQIPPPAHPAPVHQPPPLP 417
Score = 33.5 bits (75), Expect = 0.73
Identities = 18/64 (28%), Positives = 30/64 (46%), Gaps = 2/64 (3%)
Query: 91 SSDNPQPEMAPPVHEPRAELAPPAPPLPPLPPERTSGIGDSRPPSFHPNVSSSHENLEPE 150
++D P+ ++ PP H PP P PP PP + G S S+ +++L+
Sbjct: 393 ATDLPKVQIPPPAHPAPVHQPPPLPHRPPPPPPSSYMTGMSTTSSYMS--GEGYQSLQSM 450
Query: 151 TETE 154
+TE
Sbjct: 451 MKTE 454
Score = 33.1 bits (74), Expect = 0.95
Identities = 20/64 (31%), Positives = 26/64 (40%), Gaps = 11/64 (17%)
Query: 97 PEMAPPVHEP-RAELAPPAPPLPPLPPERTSGIGDS----------RPPSFHPNVSSSHE 145
P PP H P + PP PP PP+PP S + PP+++PN
Sbjct: 463 PAYGPPAHLPYHPHVYPPNPPPPPVPPPPASFPPPAIPPPTPGYPPPPPTYNPNFPPPPP 522
Query: 146 NLEP 149
L P
Sbjct: 523 RLPP 526
Score = 30.4 bits (67), Expect = 6.2
Identities = 17/47 (36%), Positives = 21/47 (44%), Gaps = 5/47 (10%)
Query: 95 PQPEMAPPVHEPRAELAPPAPPLPP---LPPERTSGIGDSRPPSFHP 138
P P PP PP P LPP +PP G+G PP+ +P
Sbjct: 502 PTPGYPPPPPTYNPNFPPPPPRLPPTHAVPPHPPPGLG--LPPASYP 546
>gi|149158690 HLA-B associated transcript-2 [Homo sapiens]
Length = 2157
Score = 58.2 bits (139), Expect = 3e-08
Identities = 61/203 (30%), Positives = 75/203 (36%), Gaps = 28/203 (13%)
Query: 518 NLSLNDNDGSSGASDQDTLAPL---------PGATPWPLLPTFSYQYPAPHPYSPQPPPY 568
N+SL DG+ AS Q+ P P + P P T + P P +P+ P
Sbjct: 75 NVSLVPKDGTGWASKQEQSDPKSSDASTAQPPESQPLPASQTPASNQPKRPPAAPENTPL 134
Query: 569 -------HELSSYTYG----GGSASSQHSEGSRSSGSTRSDGGAGRTGRPEERAPESKSG 617
+S T+G GG ASS S SR T G E + E SG
Sbjct: 135 VPSGVKSWAQASVTHGAHGDGGRASSLLSRFSREEFPTLQAAGDQDKAAKERESAEQSSG 194
Query: 618 SGSESEPSSRGGSLRRGGEASGTSDGGPPPSRGSTGGAPNLRAHPGLHPYGPPPGMALPY 677
G P + + R G G + P S+ G P GL P GPP PY
Sbjct: 195 PGPSLRPQN--STTWRDGGGRGPDELEGPDSKLHHGHDPR----GGLQPSGPP--QFPPY 246
Query: 678 NPMMVVMMPPPPPPVPPAVQPPG 700
MM M PP P PP P G
Sbjct: 247 RGMMPPFMYPPYLPFPPPYGPQG 269
Score = 42.7 bits (99), Expect = 0.001
Identities = 54/190 (28%), Positives = 66/190 (34%), Gaps = 31/190 (16%)
Query: 536 LAPLPG----ATPWPLLPTFSYQYPAPHPYSPQPPPYHELSSYTYGGGSASSQHSEGSRS 591
LA PG P P + F + P P P P PP E++ E ++
Sbjct: 835 LASYPGFPENGAPGPPISRFPLEEPGPRPL-PWPPGSDEVAKIQTPPPKKEPPKEETAQL 893
Query: 592 SGSTRSDGGAGRTGRPEE-RAPESKSGSGSESEPSSRGGSLR--RGGEASGTSDGGPPPS 648
+G PE R P GSG + P R S R G G+S G PP
Sbjct: 894 TG-------------PEAGRKPARGVGSGGQGPPPPRRESRTETRWGPRPGSSRRGIPPE 940
Query: 649 RGSTGGAPNLRAHPGLHPYGPPPGMALPYNPM-MVVMMPPPPPPVPPAVQ------PPGA 701
GAP RA P P P LP P+ P PP P P + P
Sbjct: 941 EP---GAPPRRAGPIKKPPPPTKVEELPPKPLEQGDETPKPPKPDPLKITKGKLGGPKET 997
Query: 702 PPVRDLGSVP 711
PP +L P
Sbjct: 998 PPNGNLSPAP 1007
Score = 41.6 bits (96), Expect = 0.003
Identities = 50/190 (26%), Positives = 61/190 (32%), Gaps = 52/190 (27%)
Query: 547 LLPTFSYQYPAPHPYSPQPPPYHELSSYTY--GGGSASSQHSEGSRSSG----------- 593
++P F Y PY P PPPY Y Y G + G R SG
Sbjct: 249 MMPPFMYP-----PYLPFPPPYGPQGPYRYPTPDGPSRFPRVAGPRGSGPPMRLVEPVGR 303
Query: 594 ----------------STRSDGGAGRTGRPE--ERAPESKSGSGSESEPSSRGGSLRRGG 635
DG AG + E+ S G +S+ G R
Sbjct: 304 PSILKEDNLKEFDQLDQENDDGWAGAHEEVDYTEKLKFSDEEDGRDSDEEGAEGH-RDSQ 362
Query: 636 EASGTSDGGPPPSRGSTGGAPNLRAHPGLHPYGPPPGMALPYNPMMVVMMPPPPPPVPPA 695
ASG + PP + G G +PN PP P PP P PPA
Sbjct: 363 SASG--EERPPEADGKKGNSPN----------SEPP---TPKTAWAETSRPPETEPGPPA 407
Query: 696 VQPPGAPPVR 705
+PP PP R
Sbjct: 408 PKPPLPPPHR 417
Score = 38.1 bits (87), Expect = 0.029
Identities = 30/88 (34%), Positives = 36/88 (40%), Gaps = 12/88 (13%)
Query: 95 PQPEMAPPVHEPRAELAPPAPPLPPLPPERTSGIGDSRPPSFHPNVSSSH-ENLEPETET 153
P+ A P E PPAP PPLPP G+ PP +P+ + PE E
Sbjct: 388 PKTAWAETSRPPETEPGPPAPK-PPLPPPHRGPAGNWGPPGDYPDRGGPPCKPPAPEDED 446
Query: 154 E----------SVVSLRRERPRRRDSSE 171
E S +SL ER RRR E
Sbjct: 447 EAWRQRRKQSSSEISLAVERARRRREEE 474
Score = 33.5 bits (75), Expect = 0.73
Identities = 38/145 (26%), Positives = 54/145 (37%), Gaps = 24/145 (16%)
Query: 565 PPPYHELSSYTYGGGSASSQHSEGSRSSGS-TRSDGGAGRTGRPEERAPESKSGSGSE-- 621
P P +S T GS + + R GS T S+ ++ AP K G+ ++
Sbjct: 1077 PAPRGRTASETRSEGSEYEEIPKRRRQRGSETGSETHESDLAPSDKEAPTPKEGTLTQVP 1136
Query: 622 -------SEPSSRGGSLR-RGGEASGTSDGGPPPSRGSTGGAPNLRAHPGLHPYGPPPGM 673
+ PS RGG + G P RG GG P + PG + PP
Sbjct: 1137 LAPPPPGAPPSPAPARFTARGGRVF--TPRGVPSRRGRGGGRPPPQVCPG---WSPPAKS 1191
Query: 674 ALPYNPMMVVMMPPPPPPVPPAVQP 698
P PP P+PP+ +P
Sbjct: 1192 LAP--------KKPPTGPLPPSKEP 1208
Score = 32.7 bits (73), Expect = 1.2
Identities = 41/171 (23%), Positives = 57/171 (33%), Gaps = 25/171 (14%)
Query: 95 PQPEMAPPVHEPRAELAPPAPPLPPLPPERTSGIGDSRPPSFHPNVSSSHENLEPETETE 154
P P++ P P LAP PP PLPP + P P V+ N E
Sbjct: 1177 PPPQVCPGWSPPAKSLAPKKPPTGPLPPSKEPLKEKLIPGPLSP-VARGGSNGGSNVGME 1235
Query: 155 SVVSLRRERP------------RRRDSSEHGAGGHRTGGPS-RLERHLAGYESSSTLMT- 200
RR R RR A G PS L G E + T +T
Sbjct: 1236 DGERPRRRRHGRAQQQDKPPRFRRLKQERENAARGSEGKPSLTLPASAPGPEEALTTVTV 1295
Query: 201 ------SELESTSLGDSDEEDTMSRFSSSTEQSSASRLLKRHRRRRKQRPP 245
+ +S L + + + + +++E S RR K+ PP
Sbjct: 1296 APAPRRAAAKSPDLSNQNSDQANEEWETASESSD----FTSERRGDKEAPP 1342
Score = 32.3 bits (72), Expect = 1.6
Identities = 31/122 (25%), Positives = 42/122 (34%), Gaps = 12/122 (9%)
Query: 575 TYGGGSASSQHSEGSRSSGSTRSDGGAGRTGRPEERAPESKSGSGSESEPSSRGGSLRRG 634
T GGG G+ S S G + + + S G E + G + G
Sbjct: 1353 TPGGGGG------GAVPGISAMSRGDLSQRAKDLSKRSFSSQRPGMERQNRRPGPGGKAG 1406
Query: 635 GEASGTSDGGPPPSRGSTGGAPNLRAHPGLHPYGPPPGMALPYNPMMVVMMPPPPPPVPP 694
S + GG P + G + R+ P PP P P+ PPPPP
Sbjct: 1407 SSGSSSGGGGGGPGGRTGPGRGDKRSWPSPKNRSRPPEERPPGLPL------PPPPPSSS 1460
Query: 695 AV 696
AV
Sbjct: 1461 AV 1462
Score = 31.6 bits (70), Expect = 2.8
Identities = 48/191 (25%), Positives = 61/191 (31%), Gaps = 25/191 (13%)
Query: 537 APLPGATPWPLL-PTFSYQYPAPHPYSPQPPPYHELSSYTYGGGSASSQHSEGSRSSGST 595
AP P + P P P Q P P P P + GG ++S S GS +
Sbjct: 533 APPPASAPTPETEPEEPAQAP---PAQSTPTPGVAAAPTLVSGGGSTSSTSSGSFEASPV 589
Query: 596 RSDGGAGRTGRPEERAPESKSGSGSESEPSSRGGSLRRGGEASGTSDGGPP-----PSRG 650
+ P E P + + EP G R + G G P P R
Sbjct: 590 EPQLPSKEGPEPPEEVPPPTTPPVPKVEPKGDGIGPTRQPPSQGL--GYPKYQKSLPPRF 647
Query: 651 STGGAPNLRAHPGLHPYG--------PPPGMALPYNPMMVVMMPPPP-PPVPPAVQPPGA 701
L H + P P P P+ + +P P PP PP PGA
Sbjct: 648 QRQQQEQLLKQQQQHQWQQHQQGSAPPTPVPPSPPQPVTLGAVPAPQAPPPPPKALYPGA 707
Query: 702 PPVRDLGSVPP 712
LG PP
Sbjct: 708 -----LGRPPP 713
Score = 31.6 bits (70), Expect = 2.8
Identities = 29/92 (31%), Positives = 36/92 (39%), Gaps = 13/92 (14%)
Query: 631 LRRGGEASGTSDGGPP-----PSRGSTGGAPNLRAHPGLHPYGPPPGMALPYNPMMVVMM 685
L+ GG++ G P P S N + P P PPP LP P +
Sbjct: 1961 LQPGGQSGFLPSGAPAQQMLLPMVDSQLPVVNFGSLPPAPPPAPPPLSLLPVGPAL---- 2016
Query: 686 PPPPPPVPPAVQPPGAPPVRDLGSVPPELTAS 717
PP + AV+PP AP R L S AS
Sbjct: 2017 --QPPSL--AVRPPPAPATRVLPSPARPFPAS 2044
Score = 30.8 bits (68), Expect = 4.7
Identities = 51/213 (23%), Positives = 64/213 (30%), Gaps = 41/213 (19%)
Query: 525 DGSSGASDQDTLAPLPGATPWPLLPTFSYQYPAPHPYSPQPPPYHELSSYTYGGGSASSQ 584
D GA D+ A P P P P P PPP + T A +
Sbjct: 494 DEKFGAPDKRLKAEPAAPPAAPSTPAPPPAVPKELPAPPAPPPASAPTPETEPEEPAQAP 553
Query: 585 HSEGSRSSGSTRSDGGAGRTGRPEERAPESKSGSGSESEPSSRGGSLRRGGEASGTSDGG 644
++ ST + G A AP SG GS S SS + +G
Sbjct: 554 PAQ------STPTPGVAA--------APTLVSGGGSTSSTSSGSFEASPVEPQLPSKEGP 599
Query: 645 PPPSRGSTGGAPNL-RAHP---GLHPYGPPPGMALPYNPMMVVMMPP------------- 687
PP P + + P G+ P PP L Y P +PP
Sbjct: 600 EPPEEVPPPTTPPVPKVEPKGDGIGPTRQPPSQGLGY-PKYQKSLPPRFQRQQQEQLLKQ 658
Query: 688 ---------PPPPVPPAVQPPGAPPVRDLGSVP 711
PP PP P LG+VP
Sbjct: 659 QQQHQWQQHQQGSAPPTPVPPSPPQPVTLGAVP 691
Score = 30.8 bits (68), Expect = 4.7
Identities = 19/59 (32%), Positives = 22/59 (37%), Gaps = 2/59 (3%)
Query: 654 GAPNLRAHPGLHPYGPPPGMALPYNPMMVVMMPPPPPPVPPAVQPPGAPPVRDLGSVPP 712
GAP+ R P PP + P P V P PP PPA P + PP
Sbjct: 498 GAPDKRLKA--EPAAPPAAPSTPAPPPAVPKELPAPPAPPPASAPTPETEPEEPAQAPP 554
Score = 30.8 bits (68), Expect = 4.7
Identities = 30/126 (23%), Positives = 45/126 (35%), Gaps = 15/126 (11%)
Query: 607 PEERAPESKSGSGSESEPSSRGGSLRRGGEASGTSDGGPPPSRGSTGGAPNLRAHPGLHP 666
P AP S E+EP + +++ T P+ S GG+ + +
Sbjct: 529 PAPPAPPPASAPTPETEPEEPAQA--PPAQSTPTPGVAAAPTLVSGGGSTSSTSSGSFEA 586
Query: 667 YGPPPGMALPYNPMMVVMMPPPPPPVPPAVQPPG-------APPVRDLG------SVPPE 713
P + P +PPP P P V+P G PP + LG S+PP
Sbjct: 587 SPVEPQLPSKEGPEPPEEVPPPTTPPVPKVEPKGDGIGPTRQPPSQGLGYPKYQKSLPPR 646
Query: 714 LTASRQ 719
+Q
Sbjct: 647 FQRQQQ 652
Score = 30.8 bits (68), Expect = 4.7
Identities = 22/80 (27%), Positives = 30/80 (37%), Gaps = 2/80 (2%)
Query: 612 PESKSGSGSESEPSSRGGSLRRGGEASGTSDGGPPPSRGSTGGAPNLRAHPGLHPYGPPP 671
P+SK+ P R E S G P S +GGA + + HP + P
Sbjct: 1811 PQSKNLDSGHCVPEPSSSGQRLYPEVFYGSAG--PSSSQISGGAMDSQLHPNSGGFRPGT 1868
Query: 672 GMALPYNPMMVVMMPPPPPP 691
PY + + P P PP
Sbjct: 1869 PSLHPYRSQPLYLPPGPAPP 1888
Score = 30.0 bits (66), Expect = 8.0
Identities = 46/185 (24%), Positives = 61/185 (32%), Gaps = 44/185 (23%)
Query: 550 TFSYQYPAPHPYSPQPPPYHELSSYTYGGGSASSQHSEGSRSSGSTRSDGGAGRTGRPEE 609
+FS Q P + +P P GG A S GS S G GG GR ++
Sbjct: 1384 SFSSQRPGMERQNRRPGP----------GGKAGS---SGSSSGGGGGGPGGRTGPGRGDK 1430
Query: 610 RA-PESKSGSGSESE---------PSSRGGSLRRGGEASGTSDGGPPPSRGSTGGAPNLR 659
R+ P K+ S E P ++ R + ++ G +
Sbjct: 1431 RSWPSPKNRSRPPEERPPGLPLPPPPPSSSAVFRLDQVIHSNPAGIQQALAQLSSRQGSV 1490
Query: 660 AHPGLHPYGPPPGMALPYNPMMVVMMPPPPPPV-------------PPAVQPPGAPPVRD 706
PG HP P LP P P P PP P + PG P VR
Sbjct: 1491 TAPGGHPRHKP---GLPQAP----QGPSPRPPTRYEPQRVNSGLSSDPHFEEPG-PMVRG 1542
Query: 707 LGSVP 711
+G P
Sbjct: 1543 VGGTP 1547
>gi|55750053 atrophin-1 [Homo sapiens]
Length = 1190
Score = 56.6 bits (135), Expect = 8e-08
Identities = 58/208 (27%), Positives = 76/208 (36%), Gaps = 38/208 (18%)
Query: 527 SSGASDQDTLAPLPGATPW----PLLPTFSYQYPAPHPYSPQPPPYHELSSYTYGGGSAS 582
S+ + + P P TP P+ P S + AP PPP+ +L Y G G
Sbjct: 174 STPRQPEASFEPHPSVTPTGYHAPMEPPTSRMFQAP---PGAPPPHPQL--YPGGTGGVL 228
Query: 583 SQHSEGSRSSGSTRSDGGA-GRTGRPEERAPESKSGSGSESEPSSRGGSLRRGGEASGTS 641
S G + G+ S GG G P P S S SG+ P ++ + GG G
Sbjct: 229 SGPPMGPKGGGAASSVGGPNGGKQHPPPTTPISVSSSGASGAPPTKPPTTPVGG---GNL 285
Query: 642 DGGPPPSRGSTGGAPNLRAHPGLHPYG----PPPGMA--------------------LPY 677
PPP+ PNL P L P PPG+ LP
Sbjct: 286 PSAPPPAN-FPHVTPNLPPPPALRPLNNASASPPGLGAQPLPGHLPSPHAMGQGMGGLPP 344
Query: 678 NPMMVVMMPPPPPPVPPAVQPPGAPPVR 705
P + P P +PPA APP+R
Sbjct: 345 GPEKGPTLAPSPHSLPPASSSAPAPPMR 372
Score = 47.0 bits (110), Expect = 6e-05
Identities = 62/220 (28%), Positives = 78/220 (35%), Gaps = 54/220 (24%)
Query: 538 PLPGATPWPLLPTFSYQYPAPHPYSPQP---------------PPYHELSSYTYGGGS-- 580
P PGA P PL S+ HPY+ P PP H SY+ G +
Sbjct: 510 PPPGAFPHPLEGGSSHH---AHPYAMSPSLGSLRPYPPGPAHLPPPHSQVSYSQAGPNGP 566
Query: 581 --ASSQHSEGSRSSGS------TRSDGGAGRTGRPEERAPESKSGSGSESEPSSRGGSLR 632
+SS +S S S GS + S G G P P + S + S + S
Sbjct: 567 PVSSSSNSSSSTSQGSYPCSHPSPSQGPQGAP-YPFPPVPTVTTSSATLSTVIATVASSP 625
Query: 633 RGGEASGTSDGGPPP--SRGSTGGAPNLRAHPGLHPYGPP------------------PG 672
G + + S GPPP R + GA PG P PP PG
Sbjct: 626 AGYKTA--SPPGPPPYGKRAPSPGAYKTATPPGYKPGSPPSFRTGTPPGYRGTSPPAGPG 683
Query: 673 MALPYNPMMVVMMPPPPPPVPPAVQPPGAPPVRDLGSVPP 712
P +P + P P PP P+ P PP S PP
Sbjct: 684 TFKPGSP---TVGPGPLPPAGPSGLPSLPPPPAAPASGPP 720
Score = 37.0 bits (84), Expect = 0.066
Identities = 42/158 (26%), Positives = 54/158 (34%), Gaps = 13/158 (8%)
Query: 540 PGATPWPLLPTFSYQYPAPHPYSPQPPPYHELSSYTYGGGSASSQHS--EGSRSSGSTRS 597
P P P L + +P QP P H S + G G +G + S S
Sbjct: 299 PNLPPPPALRPLNNASASPPGLGAQPLPGHLPSPHAMGQGMGGLPPGPEKGPTLAPSPHS 358
Query: 598 DGGAGRTG-RPEERAPESKSGSGSESEPSSRGGSLRRGGEASGTSDGGPPPSRGSTGGAP 656
A + P R P S S S S + SS +S +S P P+ + P
Sbjct: 359 LPPASSSAPAPPMRFPYSSSSSSSAAASSS---------SSSSSSSASPFPASQALPSYP 409
Query: 657 NLRAHP-GLHPYGPPPGMALPYNPMMVVMMPPPPPPVP 693
+ P L PP P P V PPPP P
Sbjct: 410 HSFPPPTSLSVSNQPPKYTQPSLPSQAVWSQGPPPPPP 447
Score = 34.3 bits (77), Expect = 0.43
Identities = 37/142 (26%), Positives = 47/142 (33%), Gaps = 13/142 (9%)
Query: 540 PGATPWPLLPTFSYQYPAPHPYSPQPPPYHELSSYTYGGGSASSQHSEGSRSSGSTRSDG 599
PG P L + P +P PP + Y S+SS + S SS S+ +
Sbjct: 344 PGPEKGPTLAPSPHSLPPASSSAPAPP-----MRFPYSSSSSSSAAASSSSSSSSSSASP 398
Query: 600 GAGRTGRPE--ERAPESKSGSGSESEPSSRGGSLRRGGEASGTSDGGPPPSRGSTGGAPN 657
P P S S S P SL + GPPP N
Sbjct: 399 FPASQALPSYPHSFPPPTSLSVSNQPPKYTQPSL----PSQAVWSQGPPPPPPYGRLLAN 454
Query: 658 LRAHPGLHPYGPPPGMALPYNP 679
AHPG P+ P G +P
Sbjct: 455 SNAHPG--PFPPSTGAQSTAHP 474
Score = 33.9 bits (76), Expect = 0.56
Identities = 33/138 (23%), Positives = 51/138 (36%), Gaps = 12/138 (8%)
Query: 592 SGSTRSDGGAGRTGRPEERAPESKSGSGSESEPSSRGGSLRRGGEASGTSDGGPPPSRGS 651
S S + A + + E+ P +S S +S G SL G + S
Sbjct: 77 SESESEETNAPKKTKTEQELPRPQSPSDLDSLD---GRSLNDDGSSDPRDIDQDNRSTSP 133
Query: 652 TGGAPNLRAHPGLHPYGPPPGMALPYNPMMVVMMPPPPPPVPPAVQPPGAPPVRDLGSVP 711
+ +P + G G A PY+P PP PP+ QPP + P + S
Sbjct: 134 SIYSPGSVENDSDSSSGLSQGPARPYHP---------PPLFPPSPQPPDSTPRQPEASFE 184
Query: 712 PELTASRQSFHMAMGNPS 729
P + + +H M P+
Sbjct: 185 PHPSVTPTGYHAPMEPPT 202
>gi|55750041 atrophin-1 [Homo sapiens]
Length = 1190
Score = 56.6 bits (135), Expect = 8e-08
Identities = 58/208 (27%), Positives = 76/208 (36%), Gaps = 38/208 (18%)
Query: 527 SSGASDQDTLAPLPGATPW----PLLPTFSYQYPAPHPYSPQPPPYHELSSYTYGGGSAS 582
S+ + + P P TP P+ P S + AP PPP+ +L Y G G
Sbjct: 174 STPRQPEASFEPHPSVTPTGYHAPMEPPTSRMFQAP---PGAPPPHPQL--YPGGTGGVL 228
Query: 583 SQHSEGSRSSGSTRSDGGA-GRTGRPEERAPESKSGSGSESEPSSRGGSLRRGGEASGTS 641
S G + G+ S GG G P P S S SG+ P ++ + GG G
Sbjct: 229 SGPPMGPKGGGAASSVGGPNGGKQHPPPTTPISVSSSGASGAPPTKPPTTPVGG---GNL 285
Query: 642 DGGPPPSRGSTGGAPNLRAHPGLHPYG----PPPGMA--------------------LPY 677
PPP+ PNL P L P PPG+ LP
Sbjct: 286 PSAPPPAN-FPHVTPNLPPPPALRPLNNASASPPGLGAQPLPGHLPSPHAMGQGMGGLPP 344
Query: 678 NPMMVVMMPPPPPPVPPAVQPPGAPPVR 705
P + P P +PPA APP+R
Sbjct: 345 GPEKGPTLAPSPHSLPPASSSAPAPPMR 372
Score = 47.0 bits (110), Expect = 6e-05
Identities = 62/220 (28%), Positives = 78/220 (35%), Gaps = 54/220 (24%)
Query: 538 PLPGATPWPLLPTFSYQYPAPHPYSPQP---------------PPYHELSSYTYGGGS-- 580
P PGA P PL S+ HPY+ P PP H SY+ G +
Sbjct: 510 PPPGAFPHPLEGGSSHH---AHPYAMSPSLGSLRPYPPGPAHLPPPHSQVSYSQAGPNGP 566
Query: 581 --ASSQHSEGSRSSGS------TRSDGGAGRTGRPEERAPESKSGSGSESEPSSRGGSLR 632
+SS +S S S GS + S G G P P + S + S + S
Sbjct: 567 PVSSSSNSSSSTSQGSYPCSHPSPSQGPQGAP-YPFPPVPTVTTSSATLSTVIATVASSP 625
Query: 633 RGGEASGTSDGGPPP--SRGSTGGAPNLRAHPGLHPYGPP------------------PG 672
G + + S GPPP R + GA PG P PP PG
Sbjct: 626 AGYKTA--SPPGPPPYGKRAPSPGAYKTATPPGYKPGSPPSFRTGTPPGYRGTSPPAGPG 683
Query: 673 MALPYNPMMVVMMPPPPPPVPPAVQPPGAPPVRDLGSVPP 712
P +P + P P PP P+ P PP S PP
Sbjct: 684 TFKPGSP---TVGPGPLPPAGPSGLPSLPPPPAAPASGPP 720
Score = 37.0 bits (84), Expect = 0.066
Identities = 42/158 (26%), Positives = 54/158 (34%), Gaps = 13/158 (8%)
Query: 540 PGATPWPLLPTFSYQYPAPHPYSPQPPPYHELSSYTYGGGSASSQHS--EGSRSSGSTRS 597
P P P L + +P QP P H S + G G +G + S S
Sbjct: 299 PNLPPPPALRPLNNASASPPGLGAQPLPGHLPSPHAMGQGMGGLPPGPEKGPTLAPSPHS 358
Query: 598 DGGAGRTG-RPEERAPESKSGSGSESEPSSRGGSLRRGGEASGTSDGGPPPSRGSTGGAP 656
A + P R P S S S S + SS +S +S P P+ + P
Sbjct: 359 LPPASSSAPAPPMRFPYSSSSSSSAAASSS---------SSSSSSSASPFPASQALPSYP 409
Query: 657 NLRAHP-GLHPYGPPPGMALPYNPMMVVMMPPPPPPVP 693
+ P L PP P P V PPPP P
Sbjct: 410 HSFPPPTSLSVSNQPPKYTQPSLPSQAVWSQGPPPPPP 447
Score = 34.3 bits (77), Expect = 0.43
Identities = 37/142 (26%), Positives = 47/142 (33%), Gaps = 13/142 (9%)
Query: 540 PGATPWPLLPTFSYQYPAPHPYSPQPPPYHELSSYTYGGGSASSQHSEGSRSSGSTRSDG 599
PG P L + P +P PP + Y S+SS + S SS S+ +
Sbjct: 344 PGPEKGPTLAPSPHSLPPASSSAPAPP-----MRFPYSSSSSSSAAASSSSSSSSSSASP 398
Query: 600 GAGRTGRPE--ERAPESKSGSGSESEPSSRGGSLRRGGEASGTSDGGPPPSRGSTGGAPN 657
P P S S S P SL + GPPP N
Sbjct: 399 FPASQALPSYPHSFPPPTSLSVSNQPPKYTQPSL----PSQAVWSQGPPPPPPYGRLLAN 454
Query: 658 LRAHPGLHPYGPPPGMALPYNP 679
AHPG P+ P G +P
Sbjct: 455 SNAHPG--PFPPSTGAQSTAHP 474
Score = 33.9 bits (76), Expect = 0.56
Identities = 33/138 (23%), Positives = 51/138 (36%), Gaps = 12/138 (8%)
Query: 592 SGSTRSDGGAGRTGRPEERAPESKSGSGSESEPSSRGGSLRRGGEASGTSDGGPPPSRGS 651
S S + A + + E+ P +S S +S G SL G + S
Sbjct: 77 SESESEETNAPKKTKTEQELPRPQSPSDLDSLD---GRSLNDDGSSDPRDIDQDNRSTSP 133
Query: 652 TGGAPNLRAHPGLHPYGPPPGMALPYNPMMVVMMPPPPPPVPPAVQPPGAPPVRDLGSVP 711
+ +P + G G A PY+P PP PP+ QPP + P + S
Sbjct: 134 SIYSPGSVENDSDSSSGLSQGPARPYHP---------PPLFPPSPQPPDSTPRQPEASFE 184
Query: 712 PELTASRQSFHMAMGNPS 729
P + + +H M P+
Sbjct: 185 PHPSVTPTGYHAPMEPPT 202
>gi|170650694 centaurin, gamma 1 isoform PIKE-L [Homo sapiens]
Length = 1192
Score = 56.2 bits (134), Expect = 1e-07
Identities = 53/207 (25%), Positives = 74/207 (35%), Gaps = 47/207 (22%)
Query: 538 PLPGATPW----PLLPTFSYQYP--------------APHP--------YSPQPPPYHEL 571
P PG P PLL + S+ P +PHP +P PP
Sbjct: 131 PKPGGAPTSSRRPLLSSPSWGGPEPEGRAGGGIPGSSSPHPGTGSRRLKVAPPPPAPKPC 190
Query: 572 SSYTYGGGSASSQHSEGSRSSGSTRSDGGAGRTGRPEERAPESKSGSGSESEPSSRGGSL 631
+ T G A GSR S G+P + +S +G+G+ ++ +
Sbjct: 191 KTVTTSGAKAGGGKGAGSRLSWPESE-------GKPRVKGSKSSAGTGASVSAAATAAAA 243
Query: 632 RRGGEASGTSD---------GGPPPSRGSTGGAPNLRAHPGLHPYGPPPGMALPYNP--- 679
GG + TS G P +G + N HPG P G PP + LP P
Sbjct: 244 GGGGSTASTSGGVGAGAGARGKLSPRKGKSKTLDNSDLHPG-PPAGSPPPLTLPPTPSPA 302
Query: 680 -MMVVMMPPPPPPVPPAVQPPGAPPVR 705
+ PP P PP P AP ++
Sbjct: 303 TAVTAASAQPPGPAPPITLEPPAPGLK 329
Score = 30.4 bits (67), Expect = 6.2
Identities = 30/94 (31%), Positives = 39/94 (41%), Gaps = 4/94 (4%)
Query: 528 SGASDQDTLAPLPGATPWPLLPTFSYQYPAPHPYSPQPPPYHELSSYTYGGGSASSQHSE 587
+G+ TL P P +P + S Q P P P PP L GG +++
Sbjct: 287 AGSPPPLTLPPTP--SPATAVTAASAQPPGPAPPITLEPPAPGLKRGREGGRASTRDRKM 344
Query: 588 GSRSSGS-TRSDGGAGRTGRPEERAPESKSGSGS 620
SG T+S GG +G P P SGSGS
Sbjct: 345 LKFISGIFTKSTGGPPGSG-PLPGPPSLSSGSGS 377
>gi|140972063 protein phosphatase 1, regulatory subunit 9B [Homo
sapiens]
Length = 817
Score = 56.2 bits (134), Expect = 1e-07
Identities = 63/249 (25%), Positives = 102/249 (40%), Gaps = 26/249 (10%)
Query: 100 APPVHEPRAELAPPAPPLPPLPPERTSGIGDSRPPSFHPNVSSSHENLEPETETESVVSL 159
+P EP+A+ AP PPER G+G+ R P P + E +E + V
Sbjct: 340 SPAPEEPKAQAAPEKEAAAVAPPER--GVGNGRAPDVAPEEVDESKK-EDFSEADLV--- 393
Query: 160 RRERPRRRDSSEHGAGGHRTGGPSRLERHLAGYESSSTLMTSELESTSL-GDSDEEDTMS 218
D S + G + G + E E E + G S+EED
Sbjct: 394 --------DVSAYSGLGEDSAGSALEEDDEDDEEDGEPPYEPESGCVEIPGLSEEEDPAP 445
Query: 219 ----RFSSSTEQSSASRLLKRHRRRRKQRPPRLERTSSFSSVTDSTMSLNIITVTLNMEK 274
FS++ Q ++ + + RR + P S+ + L + V L +
Sbjct: 446 SRKIHFSTAPIQVFSTYSNEDYDRRNEDVDPMA--ASAEYELEKRVERLELFPVELEKDS 503
Query: 275 YNFLGISIVGQSNERGDG----GIYIGSIMKGGAVAADGRIEPGDMLLQVNDMNFENMSN 330
LGISI+G G GI++ ++ +GGA DGRI+ D+L++V+ + ++
Sbjct: 504 EG-LGISIIGMGAGADMGLEKLGIFVKTVTEGGAAHRDGRIQVNDLLVEVDGTSLVGVTQ 562
Query: 331 DDAVRVLRD 339
A VLR+
Sbjct: 563 SFAASVLRN 571
>gi|21361831 partitioning-defective protein 3 homolog [Homo sapiens]
Length = 1356
Score = 55.8 bits (133), Expect = 1e-07
Identities = 46/170 (27%), Positives = 74/170 (43%), Gaps = 18/170 (10%)
Query: 202 ELESTSLGDSDEEDTMSRFSSSTEQSSASRLLKR-----HRRRRKQRPPRLERTSSFSS- 255
E+ L +E+ +S S+ + + S L+ R H R P +++ +
Sbjct: 513 EVNGVDLVGKSQEEVVSLLRSTKMEGTVSLLVFRQEDAFHPRELNAEPSQMQIPKETKAE 572
Query: 256 ------VTDSTMSLNIITVTLNMEKYNFLGISIVGQSNERG--DGGIYIGSIMKGGAVAA 307
D T V LN LG+S+ G ++ D GI++ SI+ GGA +
Sbjct: 573 DEDIVLTPDGTREFLTFEVPLNDSGSAGLGVSVKGNRSKENHADLGIFVKSIINGGAASK 632
Query: 308 DGRIEPGDMLLQVNDMNFENMSNDDAVRVLRDIV----HKPGPIVLTVAK 353
DGR+ D L+ VN + +N DA+ LR + +K G I L VA+
Sbjct: 633 DGRLRVNDQLIAVNGESLLGKTNQDAMETLRRSMSTEGNKRGMIQLIVAR 682
Score = 42.7 bits (99), Expect = 0.001
Identities = 38/128 (29%), Positives = 59/128 (46%), Gaps = 10/128 (7%)
Query: 219 RFSSSTEQ-SSASRLLKRHRRRRKQRPPRLERTSS---FSSVTDSTMSLNIITVTLNMEK 274
R + EQ S SRL H +PP ++ FS+ S + I LN++
Sbjct: 407 RLNHPPEQIDSHSRL--PHSAHPSGKPPSAPASAPQNVFSTTVSSGYNTKKIGKRLNIQL 464
Query: 275 YNF---LGISIVGQS-NERGDGGIYIGSIMKGGAVAADGRIEPGDMLLQVNDMNFENMSN 330
LG SI + G IY+ +I+ GA DGR++ GD L++VN ++ S
Sbjct: 465 KKGTEGLGFSITSRDVTIGGSAPIYVKNILPRGAAIQDGRLKAGDRLIEVNGVDLVGKSQ 524
Query: 331 DDAVRVLR 338
++ V +LR
Sbjct: 525 EEVVSLLR 532
>gi|148833504 interleukin 16 isoform 2 [Homo sapiens]
Length = 1332
Score = 55.8 bits (133), Expect = 1e-07
Identities = 36/110 (32%), Positives = 57/110 (51%), Gaps = 3/110 (2%)
Query: 243 RPPRLERTSSFSSVTDSTMSLNIITVTLNMEKYNFLGISIVGQSNE-RGDGGIYIGSIMK 301
RP R T+ + + I + L + LG SIVG + G GIY+ +I
Sbjct: 192 RPTRSLSTAQLVQPSGGLQASVISNIVLMKGQAKGLGFSIVGGKDSIYGPIGIYVKTIFA 251
Query: 302 GGAVAADGRIEPGDMLLQVNDMNFENMSNDDAVRVLRDIVHKPGPIVLTV 351
GGA AADGR++ GD +L++N + +++ DA++ + K G + LTV
Sbjct: 252 GGAAAADGRLQEGDEILELNGESMAGLTHQDALQKFKQA--KKGLLTLTV 299
Score = 40.0 bits (92), Expect = 0.008
Identities = 26/93 (27%), Positives = 45/93 (48%), Gaps = 2/93 (2%)
Query: 258 DSTMSLNIITVTLNMEKYNFLGISIVG-QSNERGDGGIYIGSIMKGGAVAADGRIEPGDM 316
+ST + TVTL LG S+ G + + GD + I I KG A ++PGD
Sbjct: 1225 ESTAEATVCTVTLEKMSAG-LGFSLEGGKGSLHGDKPLTINRIFKGAASEQSETVQPGDE 1283
Query: 317 LLQVNDMNFENMSNDDAVRVLRDIVHKPGPIVL 349
+LQ+ + ++ +A +++ + P IV+
Sbjct: 1284 ILQLGGTAMQGLTRFEAWNIIKALPDGPVTIVI 1316
Score = 38.1 bits (87), Expect = 0.029
Identities = 36/177 (20%), Positives = 72/177 (40%), Gaps = 23/177 (12%)
Query: 202 ELESTSLGDSDEEDTMSRFSSSTEQ----SSASRLLKRHRRRRKQRPPRLERTSSFSSVT 257
EL S+ +D + +F + + + +RL PP SS + +T
Sbjct: 269 ELNGESMAGLTHQDALQKFKQAKKGLLTLTVRTRLTAPPSLCSHLSPPLCRSLSSSTCIT 328
Query: 258 --DSTMSLNIITVTLNMEKYNFLGISIVGQSNERGDG---------------GIYIGSIM 300
S+ +L + ++ K N+ + V E G G GI++ ++
Sbjct: 329 KDSSSFALESPSAPISTAKPNYRIMVEVSLQKEAGVGLGIGLCSVPYFQCISGIFVHTLS 388
Query: 301 KGGAVAADGRIEPGDMLLQVNDMNFENMSNDDAVRVLRDIVHKPGPIVLTVAKCWDP 357
G DGR+ GD +++++D ++ ++ +L PGP+ + V++ DP
Sbjct: 389 PGSVAHLDGRLRCGDEIVEISDSPVHCLTLNEVYTILSHC--DPGPVPIIVSRHPDP 443
Score = 32.7 bits (73), Expect = 1.2
Identities = 35/161 (21%), Positives = 71/161 (44%), Gaps = 12/161 (7%)
Query: 193 ESSSTLMTSELESTSLG--DSDEEDTMSRFSSSTEQSSASRLLKRHRRRRKQRPPRLERT 250
++ +L SEL + G ++ E+D S + QS S L ++ + L+
Sbjct: 1044 DTGFSLNLSELREYTEGLTEAKEDDDGDHSSLQSGQSVISLLSSEELKKLIEEVKVLDEA 1103
Query: 251 SSFSSVTDSTMSLNIITVT-LNMEKYNFLGISIVGQSNERGDGGIYIGSIMKGGAVAADG 309
+ L+ I VT L+ E+ LG S+ G ++ I + + G + +G
Sbjct: 1104 T--------LKQLDGIHVTILHKEEGAGLGFSLAGGADLENKV-ITVHRVFPNGLASQEG 1154
Query: 310 RIEPGDMLLQVNDMNFENMSNDDAVRVLRDIVHKPGPIVLT 350
I+ G+ +L +N + + ++ DA+ +LR +++T
Sbjct: 1155 TIQKGNEVLSINGKSLKGTTHHDALAILRQAREPRQAVIVT 1195
>gi|24025688 ligand of numb-protein X 2 [Homo sapiens]
Length = 690
Score = 55.8 bits (133), Expect = 1e-07
Identities = 31/102 (30%), Positives = 58/102 (56%), Gaps = 2/102 (1%)
Query: 244 PPRLERTSSFSSVTDSTMSLNIITVTLNMEKYNFLGISIVG-QSNERGDGGIYIGSIMKG 302
PP R SS +T ++ +T+ E + LG+++ G + ++ G+ I++ S+
Sbjct: 446 PPYYSRPSSHKDLTQC-VTCQEKHITVKKEPHESLGMTVAGGRGSKSGELPIFVTSVPPH 504
Query: 303 GAVAADGRIEPGDMLLQVNDMNFENMSNDDAVRVLRDIVHKP 344
G +A DGRI+ GD+LL +N ++ N+S+ +AV +L+ P
Sbjct: 505 GCLARDGRIKRGDVLLNINGIDLTNLSHSEAVAMLKASAASP 546
Score = 49.7 bits (117), Expect = 1e-05
Identities = 42/131 (32%), Positives = 61/131 (46%), Gaps = 6/131 (4%)
Query: 211 SDEEDTMSRFSSSTEQSSASRLLKRHRRRRKQRPPRLERTSSFSSVTDSTMSL---NIIT 267
S E D + + E+ S L P E ++ + T +SL I T
Sbjct: 175 SPEADCLGTGAVPVERHLTSASLSTWSEEPGLDNPAFEESAG-ADTTQQPLSLPEGEITT 233
Query: 268 VTLNMEK-YNFLGISIVGQSNERGDGGIYIGSIMKGGAVAADGRIEPGDMLLQVNDMNFE 326
+ ++ Y LGISIVG NE I I + + G +A DGR+ GD +LQVN+ N
Sbjct: 234 IEIHRSNPYIQLGISIVG-GNETPLINIVIQEVYRDGVIARDGRLLAGDQILQVNNYNIS 292
Query: 327 NMSNDDAVRVL 337
N+S++ A VL
Sbjct: 293 NVSHNYARAVL 303
Score = 38.5 bits (88), Expect = 0.023
Identities = 28/81 (34%), Positives = 43/81 (53%), Gaps = 5/81 (6%)
Query: 279 GISIVGQSNERGDGG-IYIGSIMKGGAVAADGRIEPGDMLLQVNDMNFENMSNDDAVRVL 337
G SIVG E +I +I+ G DGR++ GDM++ VN ++ MS+ V +L
Sbjct: 612 GFSIVGGYEENHTNQPFFIKTIVLGTPAYYDGRLKCGDMIVAVNGLSTVGMSHSALVPML 671
Query: 338 RDIVHKPGPIVLTVAKCWDPS 358
++ +K + LTV CW S
Sbjct: 672 KEQRNK---VTLTVI-CWPGS 688
Score = 37.7 bits (86), Expect = 0.039
Identities = 22/82 (26%), Positives = 46/82 (56%), Gaps = 6/82 (7%)
Query: 278 LGISIVGQSNERGDGGIYIGSIMKGGAVAADGRIEPGDMLLQVNDMNFENMSNDDAVRVL 337
LGI +V +++E G ++I +++GG A DGR+ D +L +N + + + + A +++
Sbjct: 351 LGIKLVRRTDEPG---VFILDLLEGGLAAQDGRLSSNDRVLAINGHDLKYGTPELAAQII 407
Query: 338 RDIVHKPGPIVLTVAKCWDPSP 359
+ + + LT+A+ P P
Sbjct: 408 QASGER---VNLTIARPGKPQP 426
>gi|239751637 PREDICTED: hypothetical protein FLJ22184 [Homo
sapiens]
Length = 1124
Score = 55.5 bits (132), Expect = 2e-07
Identities = 61/223 (27%), Positives = 85/223 (38%), Gaps = 41/223 (18%)
Query: 528 SGASDQDTLAPLPGATPWPLLPTFSYQ------YPAPHPYS-PQPPPYHELSSYTYGGGS 580
S + +DT P PG TP P + S P P P + P+PP S S
Sbjct: 157 SAGARRDTSGPTPG-TPSPAMARRSRAAGTEVGLPRPAPSARPRPPTEGPRKSV-----S 210
Query: 581 ASSQHSEGSRSSGSTRSDGGAGRTGRPEERAPESKS---GSGSESEPSSRGGSLR----- 632
++S+HS S + R G RP R+ S + S + S PS+RG
Sbjct: 211 SASEHSTTEPSPAARRRPSAGGGLQRPASRSLSSSATPLSSPARSGPSARGTPRAPAHPS 270
Query: 633 ----RGGEASGTSDGGPP-----PSRGSTGGAPNLRAHPG---LHPYGPPPGMA------ 674
+G +A PP P+ G +P P P PP A
Sbjct: 271 QPKPKGLQALRPPQVTPPRKDAAPALGPLSSSPLATPSPSGTKARPVPPPDNAATPLPAT 330
Query: 675 LPYNPMMVVMMP--PPPPPVPPAVQPPGAPPVRDLGSVPPELT 715
LP +P + +P PP P PP++Q +PP PP +T
Sbjct: 331 LPPSPPLATPLPLAPPSPSAPPSLQTLPSPPATPPSQAPPSMT 373
Score = 40.4 bits (93), Expect = 0.006
Identities = 24/76 (31%), Positives = 33/76 (43%), Gaps = 10/76 (13%)
Query: 645 PPPSRGSTGGAPNLRAHPGLHPYGPPPGMALPYNPMMVVMMPPPP-------PPVPPAVQ 697
PPP S+ P +A P L PP LP P+ + PPP PP+
Sbjct: 579 PPPETPSSIATPPPQAPPAL---ASPPLQGLPSPPLSPLATPPPQAPPXLALPPLQAPPS 635
Query: 698 PPGAPPVRDLGSVPPE 713
PP +PP+ L + P+
Sbjct: 636 PPASPPLSPLATPSPQ 651
Score = 39.3 bits (90), Expect = 0.013
Identities = 51/196 (26%), Positives = 68/196 (34%), Gaps = 41/196 (20%)
Query: 556 PAPHPYSPQPPPYHELSSYTY---------------GGGSASSQHSEGSRSSGSTRSDGG 600
P P P SP+PPP ++ GG + E + +G TRS G
Sbjct: 27 PRP-PGSPRPPPPVTPAALRVLGAAGAVGRKPLAERAGGIGGATIPESAPRAGPTRSAGT 85
Query: 601 AGRTGRPEERAPESKSGSGSESEPSSRGGSLRRGGEASGTSDGGP------------PPS 648
+ R P R P S G + ++ G + G ASGT+ GP +
Sbjct: 86 SSRN--PASRPPASGRGERAPPAKNTSPGPVSSPGRASGTTRPGPLGQKGLRISAEETVA 143
Query: 649 RGSTGGAPN---LRAHPGLHPYGPPPGMALPYNPM------MVVMMPPPPPPVPPAVQPP 699
RG AP L A GP PG P V +P P P P +PP
Sbjct: 144 RGKATEAPKRSALSAGARRDTSGPTPGTPSPAMARRSRAAGTEVGLPRPAPSARP--RPP 201
Query: 700 GAPPVRDLGSVPPELT 715
P + + S T
Sbjct: 202 TEGPRKSVSSASEHST 217
Score = 38.9 bits (89), Expect = 0.017
Identities = 45/185 (24%), Positives = 67/185 (36%), Gaps = 21/185 (11%)
Query: 540 PGATPWPLLPTFSYQYPAPHPYSPQP-PPYHELSSYTYGGGSASSQH----------SEG 588
P ATP P P P P SP PP L++ + +A + H S
Sbjct: 613 PLATPPPQAPPXLALPPLQAPPSPPASPPLSPLATPSPQAPNALAVHLLQAPFSPPPSPP 672
Query: 589 SRSSGSTRSDGGAGRTGRPEERAPESKSGSGSESEPSSRGGSLRRGGEASGTSDGGPPPS 648
++ S + + P +AP S + + PS + PPP
Sbjct: 673 VQAPFSPPASPPVSPSATPPSQAPPSLAAPPLQVPPSPPASPPM-------SPSATPPPQ 725
Query: 649 RGSTGGAPNLRAHPGLHPYGPPPGMALPYNPMMVVMMPPPPPPVPPAVQPPGAPPVRDLG 708
AP L+ P P PP + P + ++ PP VPP+ PP + P+ L
Sbjct: 726 APPPLAAPPLQVPPS-PPASPPMSPSATPPPRVPPLLAAPPLQVPPS--PPASLPMSPLA 782
Query: 709 SVPPE 713
PP+
Sbjct: 783 KPPPQ 787
Score = 38.1 bits (87), Expect = 0.029
Identities = 33/107 (30%), Positives = 41/107 (38%), Gaps = 5/107 (4%)
Query: 610 RAPESKSGSGSESEPSSRGGSLRRGGEASGTSDGGPPPSRGSTGGAPNLRAHPGLHPYGP 669
+AP S S P S S A+ S P + P+ A P + P
Sbjct: 662 QAPFSPPPSPPVQAPFSPPASPPVSPSATPPSQAPPSLAAPPLQVPPSPPASPPMSPSAT 721
Query: 670 PPGMALPYNPMMVVMMPPPPPPVPPAVQPPGAPPVRDLGSVPPELTA 716
PP A P + +PP PP PP + P PP R VPP L A
Sbjct: 722 PPPQAPPPLAAPPLQVPPSPPASPP-MSPSATPPPR----VPPLLAA 763
Score = 37.4 bits (85), Expect = 0.050
Identities = 27/85 (31%), Positives = 32/85 (37%), Gaps = 13/85 (15%)
Query: 645 PPPSRGSTGGAPNLRAHPG------LHPYGPPPGMA---LPYNPMMVVMMPPPPPPVPPA 695
PPP P L+A P L P P A L + + PPP PPV
Sbjct: 617 PPPQAPPXLALPPLQAPPSPPASPPLSPLATPSPQAPNALAVHLLQAPFSPPPSPPVQAP 676
Query: 696 VQPPGAPPVRDLGS----VPPELTA 716
PP +PPV + PP L A
Sbjct: 677 FSPPASPPVSPSATPPSQAPPSLAA 701
Score = 33.9 bits (76), Expect = 0.56
Identities = 27/76 (35%), Positives = 32/76 (42%), Gaps = 13/76 (17%)
Query: 645 PPPSRGSTGGAPNLRAHPGLHPYGPPPGMALPYNPMMVVMMPP---PPPPVPPAVQPPGA 701
PPP P L+A P P PG A P++P + M P PPP PP + P
Sbjct: 784 PPPQAPPALATPPLQALPS--PPASFPGQA-PFSPSASLPMSPLATPPPQAPPVLAAP-- 838
Query: 702 PPVRDLGSVPPELTAS 717
L VPP AS
Sbjct: 839 -----LLQVPPSPPAS 849
Score = 33.1 bits (74), Expect = 0.95
Identities = 46/175 (26%), Positives = 63/175 (36%), Gaps = 17/175 (9%)
Query: 540 PGATPWPLLPTFSYQYPAPHPYSPQPPPYHELSSYTYGGGSASSQHSEGSRSSGSTRSDG 599
P ATP P P + P+SP P P + S + S++ S
Sbjct: 644 PLATPSPQAPNALAVHLLQAPFSPPPSPPVQAPFSPPASPPVSPSATPPSQAPPSL---- 699
Query: 600 GAGRTGRPEERAPESKSGSGSESEPSSRGGSLRRGG-EASGTSDGGPPPSRGSTGG--AP 656
A + P S S S + P L + + PP S +T P
Sbjct: 700 -AAPPLQVPPSPPASPPMSPSATPPPQAPPPLAAPPLQVPPSPPASPPMSPSATPPPRVP 758
Query: 657 NLRAHPGLHPYGPPPGMALPYNPMMVVMMPPPPPPVPPAVQPPGAPPVRDLGSVP 711
L A P L P P +LP +P + PPP PPA+ PP++ L S P
Sbjct: 759 PLLAAPPLQ-VPPSPPASLPMSP-----LAKPPPQAPPAL---ATPPLQALPSPP 804
Score = 32.7 bits (73), Expect = 1.2
Identities = 21/59 (35%), Positives = 25/59 (42%), Gaps = 5/59 (8%)
Query: 645 PPPSRGSTGGAPNLRAHPGLHPYGPPPGMALPYNPMMVVMMPPPPPPVPPAVQPPGAPP 703
PPP + T AP H P P + P +P+ PPP P A PP APP
Sbjct: 543 PPPLQ--TASAPLTTPHLETPPCPAPCPLQAPPSPLTT---PPPETPSSIATPPPQAPP 596
Score = 32.3 bits (72), Expect = 1.6
Identities = 35/113 (30%), Positives = 43/113 (38%), Gaps = 23/113 (20%)
Query: 97 PEMAPPVHEPRAELAPPAPPLPPLPPERTSGIGDSRPPSFHPNVSSSHENLEPETETESV 156
P APPV LA P +PP PP + RPP+ P+ S S L T ++
Sbjct: 828 PPQAPPV------LAAPLLQVPPSPPASPTLQAPRRPPTPGPDTSVSGPRL-----TLAL 876
Query: 157 VSLRRERPRRRDSSEHGAGGHRTGGPSRLERHLAGYESSSTLMTSELESTSLG 209
P R SS GP LAG+ SS+T EL G
Sbjct: 877 APGPPPPPSRSPSS-------TLSGPD-----LAGHSSSATSTPEELRGYDSG 917
Score = 31.2 bits (69), Expect = 3.6
Identities = 24/84 (28%), Positives = 34/84 (40%), Gaps = 6/84 (7%)
Query: 646 PPSRGSTGGAPNLRAHPGLHPYGPPPGMALPYNPMMVVMMPPPPPPVPPAVQPPGAPPVR 705
PPS + L + P P PP M P PM PP +PP +Q P +
Sbjct: 345 PPSPSAPPSLQTLPSPPATPPSQAPPSMTTP--PMQA---PPSLQTIPP-IQVPHSLTSP 398
Query: 706 DLGSVPPELTASRQSFHMAMGNPS 729
L + P L S ++G+P+
Sbjct: 399 SLQAPPSPLALSSLQATTSLGSPT 422
Score = 30.8 bits (68), Expect = 4.7
Identities = 12/34 (35%), Positives = 17/34 (50%)
Query: 92 SDNPQPEMAPPVHEPRAELAPPAPPLPPLPPERT 125
S P P+ PP+ P ++ P P PP+ P T
Sbjct: 719 SATPPPQAPPPLAAPPLQVPPSPPASPPMSPSAT 752
>gi|218156340 chapsyn-110 isoform 3 [Homo sapiens]
Length = 749
Score = 55.5 bits (132), Expect = 2e-07
Identities = 32/83 (38%), Positives = 48/83 (57%), Gaps = 10/83 (12%)
Query: 278 LGISI---VGQSNERGDGGIYIGSIMKGGAVAADGRIEPGDMLLQVNDMNFENMSNDDAV 334
LG SI VG + GD IY+ I+ GGA DGR++ GD LL VN+ + E +++++AV
Sbjct: 152 LGFSIAGGVGNQHIPGDNSIYVTKIIDGGAAQKDGRLQVGDRLLMVNNYSLEEVTHEEAV 211
Query: 335 RVLRDI-------VHKPGPIVLT 350
+L++ V KP I +T
Sbjct: 212 AILKNTSEVVYLKVGKPTTIYMT 234
Score = 48.5 bits (114), Expect = 2e-05
Identities = 30/86 (34%), Positives = 47/86 (54%), Gaps = 10/86 (11%)
Query: 278 LGISIVGQSNER---GDGGIYIGSIMKGGAVAADGRIEPGDMLLQVNDMNFENMSNDDAV 334
LG SI G ++ D GI+I I+ GGA A DGR+ D +L+VN+++ +S+ AV
Sbjct: 57 LGFSIAGGTDNPHIGDDPGIFITKIIPGGAAAEDGRLRVNDCILRVNEVDVSEVSHSKAV 116
Query: 335 RVLRD-------IVHKPGPIVLTVAK 353
L++ V + PI+ TV +
Sbjct: 117 EALKEAGSIVRLYVRRRRPILETVVE 142
Score = 39.3 bits (90), Expect = 0.013
Identities = 21/61 (34%), Positives = 34/61 (55%), Gaps = 3/61 (4%)
Query: 278 LGISIVGQSNERGDGGIYIGSIMKGGAVAADGRIEPGDMLLQVNDMNFENMSNDDAVRVL 337
LG +IVG E G+G I++ I+ GG G ++ GD +L VN ++ S++ A L
Sbjct: 328 LGFNIVG--GEDGEG-IFVSFILAGGPADLSGELQRGDQILSVNGIDLRGASHEQAAAAL 384
Query: 338 R 338
+
Sbjct: 385 K 385
>gi|218156338 chapsyn-110 isoform 1 [Homo sapiens]
Length = 975
Score = 55.5 bits (132), Expect = 2e-07
Identities = 32/83 (38%), Positives = 48/83 (57%), Gaps = 10/83 (12%)
Query: 278 LGISI---VGQSNERGDGGIYIGSIMKGGAVAADGRIEPGDMLLQVNDMNFENMSNDDAV 334
LG SI VG + GD IY+ I+ GGA DGR++ GD LL VN+ + E +++++AV
Sbjct: 308 LGFSIAGGVGNQHIPGDNSIYVTKIIDGGAAQKDGRLQVGDRLLMVNNYSLEEVTHEEAV 367
Query: 335 RVLRDI-------VHKPGPIVLT 350
+L++ V KP I +T
Sbjct: 368 AILKNTSEVVYLKVGKPTTIYMT 390
Score = 48.5 bits (114), Expect = 2e-05
Identities = 30/86 (34%), Positives = 47/86 (54%), Gaps = 10/86 (11%)
Query: 278 LGISIVGQSNER---GDGGIYIGSIMKGGAVAADGRIEPGDMLLQVNDMNFENMSNDDAV 334
LG SI G ++ D GI+I I+ GGA A DGR+ D +L+VN+++ +S+ AV
Sbjct: 213 LGFSIAGGTDNPHIGDDPGIFITKIIPGGAAAEDGRLRVNDCILRVNEVDVSEVSHSKAV 272
Query: 335 RVLRD-------IVHKPGPIVLTVAK 353
L++ V + PI+ TV +
Sbjct: 273 EALKEAGSIVRLYVRRRRPILETVVE 298
Score = 39.3 bits (90), Expect = 0.013
Identities = 21/61 (34%), Positives = 34/61 (55%), Gaps = 3/61 (4%)
Query: 278 LGISIVGQSNERGDGGIYIGSIMKGGAVAADGRIEPGDMLLQVNDMNFENMSNDDAVRVL 337
LG +IVG E G+G I++ I+ GG G ++ GD +L VN ++ S++ A L
Sbjct: 536 LGFNIVG--GEDGEG-IFVSFILAGGPADLSGELQRGDQILSVNGIDLRGASHEQAAAAL 592
Query: 338 R 338
+
Sbjct: 593 K 593
>gi|91199538 chapsyn-110 isoform 2 [Homo sapiens]
Length = 870
Score = 55.5 bits (132), Expect = 2e-07
Identities = 32/83 (38%), Positives = 48/83 (57%), Gaps = 10/83 (12%)
Query: 278 LGISI---VGQSNERGDGGIYIGSIMKGGAVAADGRIEPGDMLLQVNDMNFENMSNDDAV 334
LG SI VG + GD IY+ I+ GGA DGR++ GD LL VN+ + E +++++AV
Sbjct: 203 LGFSIAGGVGNQHIPGDNSIYVTKIIDGGAAQKDGRLQVGDRLLMVNNYSLEEVTHEEAV 262
Query: 335 RVLRDI-------VHKPGPIVLT 350
+L++ V KP I +T
Sbjct: 263 AILKNTSEVVYLKVGKPTTIYMT 285
Score = 48.5 bits (114), Expect = 2e-05
Identities = 30/86 (34%), Positives = 47/86 (54%), Gaps = 10/86 (11%)
Query: 278 LGISIVGQSNER---GDGGIYIGSIMKGGAVAADGRIEPGDMLLQVNDMNFENMSNDDAV 334
LG SI G ++ D GI+I I+ GGA A DGR+ D +L+VN+++ +S+ AV
Sbjct: 108 LGFSIAGGTDNPHIGDDPGIFITKIIPGGAAAEDGRLRVNDCILRVNEVDVSEVSHSKAV 167
Query: 335 RVLRD-------IVHKPGPIVLTVAK 353
L++ V + PI+ TV +
Sbjct: 168 EALKEAGSIVRLYVRRRRPILETVVE 193
Score = 39.3 bits (90), Expect = 0.013
Identities = 21/61 (34%), Positives = 34/61 (55%), Gaps = 3/61 (4%)
Query: 278 LGISIVGQSNERGDGGIYIGSIMKGGAVAADGRIEPGDMLLQVNDMNFENMSNDDAVRVL 337
LG +IVG E G+G I++ I+ GG G ++ GD +L VN ++ S++ A L
Sbjct: 431 LGFNIVG--GEDGEG-IFVSFILAGGPADLSGELQRGDQILSVNGIDLRGASHEQAAAAL 487
Query: 338 R 338
+
Sbjct: 488 K 488
>gi|119943106 synapse-associated protein 102 isoform a [Homo
sapiens]
Length = 817
Score = 54.7 bits (130), Expect = 3e-07
Identities = 68/288 (23%), Positives = 116/288 (40%), Gaps = 63/288 (21%)
Query: 95 PQPEMAPPVHEPRAELAPPAPPLPPLPPERTSGIGDSR----PPSFHPNVSSSHENLEPE 150
P A P +A+L P + P+PP+ G + PS+ P + ++ + +
Sbjct: 60 PSQAGATPTPRTKAKLIPTGRDVGPVPPKPVPGKSTPKLNGSGPSWWPECTCTNRDWYEQ 119
Query: 151 TETESVVSLRRERPRRRDSSEHG---AGGHRT----------------GGPSRLERHLAG 191
+ E R +S G AGG GG + ++ L
Sbjct: 120 VNGSDGMFKYEEIVLERGNSGLGFSIAGGIDNPHVPDDPGIFITKIIPGGAAAMDGRLG- 178
Query: 192 YESSSTLMTSELESTSLGDSDEEDTMSRFSSSTEQSSASRLLKRHRRRRKQRPPRLERTS 251
+ L +E++ + + S + + E RL+ R R+Q PP
Sbjct: 179 -VNDCVLRVNEVDVSEVVHSRAVEALK------EAGPVVRLVVR----RRQPPP------ 221
Query: 252 SFSSVTDSTMSLNIITVTLNMEKYNFLGISI---VGQSNERGDGGIYIGSIMKGGAVAAD 308
++ M +N++ LG SI +G + GD IYI I++GGA D
Sbjct: 222 ------ETIMEVNLLKGPKG------LGFSIAGGIGNQHIPGDNSIYITKIIEGGAAQKD 269
Query: 309 GRIEPGDMLLQVNDMNFENMSNDDAVRVLRDI-------VHKPGPIVL 349
GR++ GD LL VN+ N +++ +++AV L++ V KPG + L
Sbjct: 270 GRLQIGDRLLAVNNTNLQDVRHEEAVASLKNTSDMVYLKVAKPGSLHL 317
Score = 49.3 bits (116), Expect = 1e-05
Identities = 30/86 (34%), Positives = 46/86 (53%), Gaps = 7/86 (8%)
Query: 278 LGISIVG---QSNERGDGGIYIGSIMKGGAVAADGRIEPGDMLLQVNDMNFENMSNDDAV 334
LG SI G + D GI+I I+ GGA A DGR+ D +L+VN+++ + + AV
Sbjct: 141 LGFSIAGGIDNPHVPDDPGIFITKIIPGGAAAMDGRLGVNDCVLRVNEVDVSEVVHSRAV 200
Query: 335 RVLRDIVHKPGPIVLTVAKCWDPSPQ 360
L++ GP+V V + P P+
Sbjct: 201 EALKE----AGPVVRLVVRRRQPPPE 222
Score = 41.2 bits (95), Expect = 0.003
Identities = 22/61 (36%), Positives = 34/61 (55%), Gaps = 3/61 (4%)
Query: 278 LGISIVGQSNERGDGGIYIGSIMKGGAVAADGRIEPGDMLLQVNDMNFENMSNDDAVRVL 337
LG +IVG E G+G I++ I+ GG G + GD +L VN +N N +++ A L
Sbjct: 396 LGFNIVG--GEDGEG-IFVSFILAGGPADLSGELRRGDRILSVNGVNLRNATHEQAAAAL 452
Query: 338 R 338
+
Sbjct: 453 K 453
>gi|157388993 synaptojanin 2 binding protein [Homo sapiens]
Length = 145
Score = 54.7 bits (130), Expect = 3e-07
Identities = 26/65 (40%), Positives = 42/65 (64%), Gaps = 3/65 (4%)
Query: 278 LGISIVGQSNER---GDGGIYIGSIMKGGAVAADGRIEPGDMLLQVNDMNFENMSNDDAV 334
LG +IVG ++++ D GIY+ I + GA A DGR++ GD +L VN + +N+ + DAV
Sbjct: 23 LGFNIVGGTDQQYVSNDSGIYVSRIKENGAAALDGRLQEGDKILSVNGQDLKNLLHQDAV 82
Query: 335 RVLRD 339
+ R+
Sbjct: 83 DLFRN 87
>gi|87196343 PDZ domain containing 2 [Homo sapiens]
Length = 2839
Score = 53.9 bits (128), Expect = 5e-07
Identities = 46/141 (32%), Positives = 68/141 (48%), Gaps = 22/141 (15%)
Query: 231 RLLKRHRRRRKQRPPRLERTSSFSS----VTDSTMSLN---------------IITVTLN 271
R+L+ R RK P+L +SS S V ST SL+ I + L
Sbjct: 531 RMLEVSRDGRKHSLPQLLDSSSASQEYHIVKKSTRSLSTTQVESPWRLIRPSVISIIGLY 590
Query: 272 MEKYNFLGISIVGQSN-ERGDGGIYIGSIMKGGAVAADGRIEPGDMLLQVNDMNFENMSN 330
EK LG SI G + RG GI++ +I G+ A DGR++ GD +L VN + + ++
Sbjct: 591 KEKGKGLGFSIAGGRDCIRGQMGIFVKTIFPNGSAAEDGRLKEGDEILDVNGIPIKGLTF 650
Query: 331 DDAVRVLRDIVHKPGPIVLTV 351
+A+ + I + G VLTV
Sbjct: 651 QEAIHTFKQI--RSGLFVLTV 669
Score = 45.4 bits (106), Expect = 2e-04
Identities = 31/111 (27%), Positives = 49/111 (44%), Gaps = 4/111 (3%)
Query: 250 TSSFSSVTDSTMSLNIITVTLNMEKYNFLGISIVGQSNERGDGGIYIGSIMKGGAVAADG 309
+SS T ++ VTLN E LGI + E GIYI S+ G +
Sbjct: 711 SSSLGRKTPGPKDRIVMEVTLNKEPRVGLGIGACCLALENSPPGIYIHSLAPGSVAKMES 770
Query: 310 RIEPGDMLLQVNDMNFENMSNDDAVRVLRDIVHKPGPIVLTVAKCWDPSPQ 360
+ GD +L+VN +N + + +L PGP+ L + + P+P+
Sbjct: 771 NLSRGDQILEVNSVNVRHAALSKVHAILSKC--PPGPVRLVIGR--HPNPK 817
Score = 44.3 bits (103), Expect = 4e-04
Identities = 26/77 (33%), Positives = 42/77 (54%), Gaps = 3/77 (3%)
Query: 278 LGISIVG-QSNERGDGGIYIGSIMKGGAVAADGRIEPGDMLLQVNDMNFENMSNDDAVRV 336
LG+S+ G +S+ GDG + I + KGGA G IE GD +L +N + + DA +
Sbjct: 2760 LGLSLDGGKSSVTGDGPLVIKRVYKGGAAEQAGIIEAGDEILAINGKPLVGLMHFDAWNI 2819
Query: 337 LRDIVHKPGPIVLTVAK 353
++ + GP+ L + K
Sbjct: 2820 MKSV--PEGPVQLLIRK 2834
Score = 42.7 bits (99), Expect = 0.001
Identities = 26/76 (34%), Positives = 41/76 (53%), Gaps = 4/76 (5%)
Query: 278 LGISIVG-QSNERGDGGIYIGSIMKGGAVAADGRIEPGDMLLQVNDMNFENMSNDDAVRV 336
LGI + G + ++R I + + +GGA DGR+ GD LL +N +S+++AV +
Sbjct: 344 LGIQVSGGRGSKRSPHAIVVTQVKEGGAAHRDGRLSLGDELLVINGHLLVGLSHEEAVAI 403
Query: 337 LRDIVHKPGPIVLTVA 352
LR G + L VA
Sbjct: 404 LRSAT---GMVQLVVA 416
>gi|4557529 post-synaptic density protein 95 isoform 1 [Homo
sapiens]
Length = 767
Score = 53.5 bits (127), Expect = 7e-07
Identities = 27/65 (41%), Positives = 41/65 (63%), Gaps = 3/65 (4%)
Query: 278 LGISI---VGQSNERGDGGIYIGSIMKGGAVAADGRIEPGDMLLQVNDMNFENMSNDDAV 334
LG SI VG + GD IY+ I++GGA DGR++ GD +L VN + E++ ++DAV
Sbjct: 213 LGFSIAGGVGNQHIPGDNSIYVTKIIEGGAAHKDGRLQIGDKILAVNSVGLEDVMHEDAV 272
Query: 335 RVLRD 339
L++
Sbjct: 273 AALKN 277
Score = 42.4 bits (98), Expect = 0.002
Identities = 23/65 (35%), Positives = 37/65 (56%), Gaps = 3/65 (4%)
Query: 278 LGISIVGQSNER---GDGGIYIGSIMKGGAVAADGRIEPGDMLLQVNDMNFENMSNDDAV 334
LG SI G ++ D I+I I+ GGA A DGR+ D +L VN+++ +++ AV
Sbjct: 118 LGFSIAGGTDNPHIGDDPSIFITKIIPGGAAAQDGRLRVNDSILFVNEVDVREVTHSAAV 177
Query: 335 RVLRD 339
L++
Sbjct: 178 EALKE 182
Score = 41.2 bits (95), Expect = 0.003
Identities = 23/62 (37%), Positives = 35/62 (56%), Gaps = 3/62 (4%)
Query: 278 LGISIVGQSNERGDGGIYIGSIMKGGAVAADGRIEPGDMLLQVNDMNFENMSNDDAVRVL 337
LG +IVG E G+G I+I I+ GG G + GD +L VN ++ N S++ A L
Sbjct: 366 LGFNIVG--GEDGEG-IFISFILAGGPADLSGELRKGDQILSVNGVDLRNASHEQAAIAL 422
Query: 338 RD 339
++
Sbjct: 423 KN 424
>gi|90819237 myeloid/lymphoid or mixed-lineage leukemia (trithorax
homolog, Drosophila); translocated to, 4 isoform 1 [Homo
sapiens]
Length = 1834
Score = 53.5 bits (127), Expect = 7e-07
Identities = 35/90 (38%), Positives = 49/90 (54%), Gaps = 6/90 (6%)
Query: 265 IITVTLNMEKYNFLGISIVGQSNERGDG-GIYIGSIMKGGAVAADGRIEPGDMLLQVNDM 323
IITVTL +K N +G+SIV D GIY+ S++KGGA DGR+ GD LL V+
Sbjct: 1006 IITVTL--KKQNGMGLSIVAAKGAGQDKLGIYVKSVVKGGAADVDGRLAAGDQLLSVDGR 1063
Query: 324 NFENMSNDDAVRVLRDIVHKPGPIVLTVAK 353
+ +S + A ++ + L VAK
Sbjct: 1064 SLVGLSQERAAELM---TRTSSVVTLEVAK 1090
Score = 34.3 bits (77), Expect = 0.43
Identities = 49/195 (25%), Positives = 67/195 (34%), Gaps = 17/195 (8%)
Query: 510 GGCESYLVNLSLNDNDGSSG--ASDQDTLAPLPGATPWPLLPTFSYQY---PAPHPYSPQ 564
GG +Y + S+G +++ T P P A P P T++ +Y PA
Sbjct: 1183 GGKSAYASGTTAKITSVSTGNLCTEEQTPPPRPEAYPIPT-QTYTREYFTFPASKSQDRM 1241
Query: 565 PPPYHELSSYTYGGGS-ASSQHSE-----GSRSSGSTRSDGGAGRTGRPEERAPESKSGS 618
PP ++ +Y S HS +RS R D E A + KS S
Sbjct: 1242 APPQNQWPNYEEKPHMHTDSNHSSIAIQRVTRSQEELREDKAYQLERHRIEAAMDRKSDS 1301
Query: 619 GSESEPSSRGGSLRRGGEASGTSDGGPPPSRGSTGGAPNLRAHPGLHPYGPPPGMALPYN 678
SS S E S P+ T P P P P ++ P
Sbjct: 1302 DMWINQSSSLDSSTSSQEHLNHSSKSVTPASTLTKSGPGRWKTPAAIP-ATPVAVSQPIR 1360
Query: 679 PMMVVMMPPPPPPVP 693
+PPPPPP P
Sbjct: 1361 ----TDLPPPPPPPP 1371
>gi|90819233 myeloid/lymphoid or mixed-lineage leukemia (trithorax
homolog, Drosophila); translocated to, 4 isoform 2 [Homo
sapiens]
Length = 1651
Score = 53.5 bits (127), Expect = 7e-07
Identities = 35/90 (38%), Positives = 49/90 (54%), Gaps = 6/90 (6%)
Query: 265 IITVTLNMEKYNFLGISIVGQSNERGDG-GIYIGSIMKGGAVAADGRIEPGDMLLQVNDM 323
IITVTL +K N +G+SIV D GIY+ S++KGGA DGR+ GD LL V+
Sbjct: 1007 IITVTL--KKQNGMGLSIVAAKGAGQDKLGIYVKSVVKGGAADVDGRLAAGDQLLSVDGR 1064
Query: 324 NFENMSNDDAVRVLRDIVHKPGPIVLTVAK 353
+ +S + A ++ + L VAK
Sbjct: 1065 SLVGLSQERAAELM---TRTSSVVTLEVAK 1091
Score = 34.3 bits (77), Expect = 0.43
Identities = 49/195 (25%), Positives = 67/195 (34%), Gaps = 17/195 (8%)
Query: 510 GGCESYLVNLSLNDNDGSSG--ASDQDTLAPLPGATPWPLLPTFSYQY---PAPHPYSPQ 564
GG +Y + S+G +++ T P P A P P T++ +Y PA
Sbjct: 1184 GGKSAYASGTTAKITSVSTGNLCTEEQTPPPRPEAYPIPT-QTYTREYFTFPASKSQDRM 1242
Query: 565 PPPYHELSSYTYGGGS-ASSQHSE-----GSRSSGSTRSDGGAGRTGRPEERAPESKSGS 618
PP ++ +Y S HS +RS R D E A + KS S
Sbjct: 1243 APPQNQWPNYEEKPHMHTDSNHSSIAIQRVTRSQEELREDKAYQLERHRIEAAMDRKSDS 1302
Query: 619 GSESEPSSRGGSLRRGGEASGTSDGGPPPSRGSTGGAPNLRAHPGLHPYGPPPGMALPYN 678
SS S E S P+ T P P P P ++ P
Sbjct: 1303 DMWINQSSSLDSSTSSQEHLNHSSKSVTPASTLTKSGPGRWKTPAAIP-ATPVAVSQPIR 1361
Query: 679 PMMVVMMPPPPPPVP 693
+PPPPPP P
Sbjct: 1362 ----TDLPPPPPPPP 1372
>gi|90819231 myeloid/lymphoid or mixed-lineage leukemia (trithorax
homolog, Drosophila); translocated to, 4 isoform 3 [Homo
sapiens]
Length = 1612
Score = 53.5 bits (127), Expect = 7e-07
Identities = 35/90 (38%), Positives = 49/90 (54%), Gaps = 6/90 (6%)
Query: 265 IITVTLNMEKYNFLGISIVGQSNERGDG-GIYIGSIMKGGAVAADGRIEPGDMLLQVNDM 323
IITVTL +K N +G+SIV D GIY+ S++KGGA DGR+ GD LL V+
Sbjct: 991 IITVTL--KKQNGMGLSIVAAKGAGQDKLGIYVKSVVKGGAADVDGRLAAGDQLLSVDGR 1048
Query: 324 NFENMSNDDAVRVLRDIVHKPGPIVLTVAK 353
+ +S + A ++ + L VAK
Sbjct: 1049 SLVGLSQERAAELM---TRTSSVVTLEVAK 1075
Score = 34.3 bits (77), Expect = 0.43
Identities = 49/195 (25%), Positives = 67/195 (34%), Gaps = 17/195 (8%)
Query: 510 GGCESYLVNLSLNDNDGSSG--ASDQDTLAPLPGATPWPLLPTFSYQY---PAPHPYSPQ 564
GG +Y + S+G +++ T P P A P P T++ +Y PA
Sbjct: 1168 GGKSAYASGTTAKITSVSTGNLCTEEQTPPPRPEAYPIPT-QTYTREYFTFPASKSQDRM 1226
Query: 565 PPPYHELSSYTYGGGS-ASSQHSE-----GSRSSGSTRSDGGAGRTGRPEERAPESKSGS 618
PP ++ +Y S HS +RS R D E A + KS S
Sbjct: 1227 APPQNQWPNYEEKPHMHTDSNHSSIAIQRVTRSQEELREDKAYQLERHRIEAAMDRKSDS 1286
Query: 619 GSESEPSSRGGSLRRGGEASGTSDGGPPPSRGSTGGAPNLRAHPGLHPYGPPPGMALPYN 678
SS S E S P+ T P P P P ++ P
Sbjct: 1287 DMWINQSSSLDSSTSSQEHLNHSSKSVTPASTLTKSGPGRWKTPAAIP-ATPVAVSQPIR 1345
Query: 679 PMMVVMMPPPPPPVP 693
+PPPPPP P
Sbjct: 1346 ----TDLPPPPPPPP 1356
>gi|192447426 post-synaptic density protein 95 isoform 2 [Homo
sapiens]
Length = 721
Score = 53.5 bits (127), Expect = 7e-07
Identities = 27/65 (41%), Positives = 41/65 (63%), Gaps = 3/65 (4%)
Query: 278 LGISI---VGQSNERGDGGIYIGSIMKGGAVAADGRIEPGDMLLQVNDMNFENMSNDDAV 334
LG SI VG + GD IY+ I++GGA DGR++ GD +L VN + E++ ++DAV
Sbjct: 167 LGFSIAGGVGNQHIPGDNSIYVTKIIEGGAAHKDGRLQIGDKILAVNSVGLEDVMHEDAV 226
Query: 335 RVLRD 339
L++
Sbjct: 227 AALKN 231
Score = 43.1 bits (100), Expect = 0.001
Identities = 33/113 (29%), Positives = 54/113 (47%), Gaps = 13/113 (11%)
Query: 236 HRRRRKQRPPRLERTSSFSSV-----TDSTMSLNIITVTLNMEKYNF-LGISIVGQSNER 289
H + PP + T + + T+ M IT +E+ N LG SI G ++
Sbjct: 28 HLPNQANSPPVIVNTDTLEAPGYVNGTEGEMEYEEIT----LERGNSGLGFSIAGGTDNP 83
Query: 290 ---GDGGIYIGSIMKGGAVAADGRIEPGDMLLQVNDMNFENMSNDDAVRVLRD 339
D I+I I+ GGA A DGR+ D +L VN+++ +++ AV L++
Sbjct: 84 HIGDDPSIFITKIIPGGAAAQDGRLRVNDSILFVNEVDVREVTHSAAVEALKE 136
Score = 41.2 bits (95), Expect = 0.003
Identities = 23/62 (37%), Positives = 35/62 (56%), Gaps = 3/62 (4%)
Query: 278 LGISIVGQSNERGDGGIYIGSIMKGGAVAADGRIEPGDMLLQVNDMNFENMSNDDAVRVL 337
LG +IVG E G+G I+I I+ GG G + GD +L VN ++ N S++ A L
Sbjct: 320 LGFNIVG--GEDGEG-IFISFILAGGPADLSGELRKGDQILSVNGVDLRNASHEQAAIAL 376
Query: 338 RD 339
++
Sbjct: 377 KN 378
>gi|112382257 InaD-like [Homo sapiens]
Length = 1801
Score = 53.5 bits (127), Expect = 7e-07
Identities = 29/77 (37%), Positives = 42/77 (54%), Gaps = 3/77 (3%)
Query: 262 SLNIITVTLNMEKYNFLGISIVGQSNERGDGGIYIGSIMKGGAVAADGRIEPGDMLLQVN 321
+L I V L + LG+SIVG+ N G++I I+KGGA DGR+ GD +L VN
Sbjct: 1528 NLEIFPVDLQKKAGRGLGLSIVGKRN---GSGVFISDIVKGGAADLDGRLIQGDQILSVN 1584
Query: 322 DMNFENMSNDDAVRVLR 338
+ N S + +L+
Sbjct: 1585 GEDMRNASQETVATILK 1601
Score = 47.4 bits (111), Expect = 5e-05
Identities = 45/154 (29%), Positives = 68/154 (44%), Gaps = 15/154 (9%)
Query: 244 PPRLERTSSFSSVTDSTMSLNIITVTLNMEKYNFLGISIVGQSNERGDG---GIYIGSIM 300
P L +S +DS++ V L + LGI IVG G GIY+ SI+
Sbjct: 343 PVALPTVASKGPGSDSSL-FETYNVELVRKDGQSLGIRIVGYVGTSHTGEASGIYVKSII 401
Query: 301 KGGAVAADGRIEPGDMLLQVNDMNFENMSNDDAVRVLRD---IVHKPGPIVLTVAKCWDP 357
G A +G I+ D ++ V+ +N + +N D V VLR+ +VH LT+ +
Sbjct: 402 PGSAAYHNGHIQVNDKIVAVDGVNIQGFANHDVVEVLRNAGQVVH------LTLVRRKTS 455
Query: 358 SPQAYFTLP--RNEPIQPIDPAAWVSHSAALTGT 389
S + P R ++P+ P A A T T
Sbjct: 456 SSTSPLEPPSDRGTVVEPLKPPALFLTGAVETET 489
Score = 47.4 bits (111), Expect = 5e-05
Identities = 31/98 (31%), Positives = 49/98 (50%), Gaps = 9/98 (9%)
Query: 278 LGISIVGQSNERGDGGIYIGSIMKGGAVAADGRIEPGDMLLQVNDMNFENMSNDDAVRVL 337
LG+SIVG + I I + + GA A DGR+ GD +L+VN ++ N S+++A+ L
Sbjct: 1447 LGLSIVG-GKDTPLNAIVIHEVYEEGAAARDGRLWAGDQILEVNGVDLRNSSHEEAITAL 1505
Query: 338 RDIVHKPGPIVLTVAKCWDPSPQAYFTLPRNEPIQPID 375
R K +V +A++ N I P+D
Sbjct: 1506 RQTPQKVRLVVY--------RDEAHYRDEENLEIFPVD 1535
Score = 44.7 bits (104), Expect = 3e-04
Identities = 27/101 (26%), Positives = 52/101 (51%), Gaps = 8/101 (7%)
Query: 243 RPPRLERTSSFSSVTDSTMSLNI----ITVTLNMEKYNFLGISIVGQSNERGDGGIYIGS 298
R P ++S+ SS+ D+T+ + + + + LG IVG G+ + +
Sbjct: 219 REPVHTKSSTSSSLNDTTLPETVCWGHVEEVELINDGSGLGFGIVGGKTS----GVVVRT 274
Query: 299 IMKGGAVAADGRIEPGDMLLQVNDMNFENMSNDDAVRVLRD 339
I+ GG DGR++ GD +L++ N + M+++ +VLR+
Sbjct: 275 IVPGGLADRDGRLQTGDHILKIGGTNVQGMTSEQVAQVLRN 315
Score = 42.4 bits (98), Expect = 0.002
Identities = 24/63 (38%), Positives = 33/63 (52%), Gaps = 3/63 (4%)
Query: 291 DGGIYIGSIMKGGAVAADGRIEPGDMLLQVNDMNFENMSNDDAVRVLRDIVHKPGPIVLT 350
DG YI SI+ GG V G ++P D LL+VN M S +AV L+++ P P L
Sbjct: 578 DGHHYISSIVSGGPVDTLGLLQPEDELLEVNGMQLYGKSRREAVSFLKEV---PPPFTLV 634
Query: 351 VAK 353
+
Sbjct: 635 CCR 637
Score = 39.7 bits (91), Expect = 0.010
Identities = 25/95 (26%), Positives = 45/95 (47%), Gaps = 1/95 (1%)
Query: 276 NFLGISIVGQSNERGDGGIYIGSIMKGGAVAADGRIEPGDMLLQVNDMNFENMSNDDAVR 335
N LG+S+ G + +R I++ I G AADGR+ GD LL++N+ S+ +A
Sbjct: 1247 NGLGLSLAG-NKDRSRMSIFVVGINPEGPAAADGRMRIGDELLEINNQILYGRSHQNASA 1305
Query: 336 VLRDIVHKPGPIVLTVAKCWDPSPQAYFTLPRNEP 370
+++ K + + + F +P + P
Sbjct: 1306 IIKTAPSKVKLVFIRNEDAVNQMAVTPFPVPSSSP 1340
Score = 35.4 bits (80), Expect = 0.19
Identities = 20/60 (33%), Positives = 32/60 (53%), Gaps = 2/60 (3%)
Query: 294 IYIGSIMKGGAVAADGRIEPGDMLLQVNDMNFENMSNDDAVRVLRDIVHKPGPIVLTVAK 353
I I S++ G G + PGD L+ VN+ +N S +AV +L+ + PG + L + K
Sbjct: 714 IVIRSLVADGVAERSGGLLPGDRLVSVNEYCLDNTSLAEAVEILKAV--PPGLVHLGICK 771
Score = 34.7 bits (78), Expect = 0.33
Identities = 19/69 (27%), Positives = 38/69 (55%), Gaps = 7/69 (10%)
Query: 278 LGISIVGQSN-----ERGDG--GIYIGSIMKGGAVAADGRIEPGDMLLQVNDMNFENMSN 330
LGISIVG + G+ GI+I +++ ++ GD +L+V+ ++ +N S+
Sbjct: 1079 LGISIVGGQTVIKRLKNGEELKGIFIKQVLEDSPAGKTNALKTGDKILEVSGVDLQNASH 1138
Query: 331 DDAVRVLRD 339
+AV +++
Sbjct: 1139 SEAVEAIKN 1147
Database: hs.faa
Posted date: Aug 4, 2009 4:42 PM
Number of letters in database: 18,247,518
Number of sequences in database: 37,866
Lambda K H
0.312 0.132 0.395
Gapped
Lambda K H
0.267 0.0410 0.140
Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Hits to DB: 37,728,528
Number of Sequences: 37866
Number of extensions: 2441386
Number of successful extensions: 38304
Number of sequences better than 10.0: 30
Number of HSP's better than 10.0 without gapping: 560
Number of HSP's successfully gapped in prelim test: 1445
Number of HSP's that attempted gapping in prelim test: 16349
Number of HSP's gapped (non-prelim): 14989
length of query: 736
length of database: 18,247,518
effective HSP length: 110
effective length of query: 626
effective length of database: 14,082,258
effective search space: 8815493508
effective search space used: 8815493508
T: 11
A: 40
X1: 16 ( 7.2 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 42 (21.8 bits)
S2: 66 (30.0 bits)
Search results were obtained with NCBI BLAST and RefSeq entries.
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Guide to the Human Genome
Copyright © 2010 by Stewart Scherer. All rights reserved.