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Search of human proteins with 4757960
BLASTP 2.2.11 [Jun-05-2005]
Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer,
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997),
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs", Nucleic Acids Res. 25:3389-3402.
Query= gi|4757960 cadherin 1, type 1 preproprotein [Homo sapiens]
(882 letters)
Database: hs.faa
37,866 sequences; 18,247,518 total letters
Searching..................................................done
Score E
Sequences producing significant alignments: (bits) Value
gi|4757960 cadherin 1, type 1 preproprotein [Homo sapiens] 1786 0.0
gi|14589891 cadherin 3, type 1 preproprotein [Homo sapiens] 922 0.0
gi|14589889 cadherin 2, type 1 preproprotein [Homo sapiens] 736 0.0
gi|14589893 cadherin 4, type 1 preproprotein [Homo sapiens] 712 0.0
gi|4826669 cadherin 15 preproprotein [Homo sapiens] 496 e-140
gi|16306487 cadherin 7, type 2 preproprotein [Homo sapiens] 405 e-113
gi|16306489 cadherin 7, type 2 preproprotein [Homo sapiens] 405 e-113
gi|4502719 cadherin 13 preproprotein [Homo sapiens] 396 e-110
gi|4826673 cadherin 6, type 2 preproprotein [Homo sapiens] 393 e-109
gi|16306530 cadherin 10, type 2 preproprotein [Homo sapiens] 389 e-108
gi|4826702 desmocollin 1 isoform Dsc1b preproprotein [Homo sapiens] 380 e-105
gi|13435361 desmocollin 1 isoform Dsc1a preproprotein [Homo sapi... 380 e-105
gi|16306539 cadherin 8, type 2 preproprotein [Homo sapiens] 376 e-104
gi|16306532 cadherin 11, type 2 preproprotein [Homo sapiens] 374 e-103
gi|4826671 cadherin 18, type 2 preproprotein [Homo sapiens] 373 e-103
gi|90193626 cadherin 9, type 2 preproprotein [Homo sapiens] 371 e-102
gi|16445393 cadherin 12, type 2 preproprotein [Homo sapiens] 370 e-102
gi|13435366 desmocollin 2 isoform Dsc2b preproprotein [Homo sapi... 355 1e-97
gi|13435364 desmocollin 2 isoform Dsc2a preproprotein [Homo sapi... 355 1e-97
gi|16306537 cadherin 20, type 2 preproprotein [Homo sapiens] 353 5e-97
gi|148539848 desmocollin 3 isoform Dsc3b preproprotein [Homo sap... 339 6e-93
gi|148539846 desmocollin 3 isoform Dsc3a preproprotein [Homo sap... 339 6e-93
gi|32880203 cadherin-like 24 isoform 2 [Homo sapiens] 330 4e-90
gi|32880206 cadherin-like 24 isoform 1 [Homo sapiens] 319 8e-87
gi|12656655 cadherin 19, type 2 preproprotein [Homo sapiens] 310 5e-84
gi|29570800 cadherin-like 26 isoform a [Homo sapiens] 307 2e-83
gi|166362713 cadherin 5, type 2 preproprotein [Homo sapiens] 306 4e-83
gi|16753221 cadherin 22 precursor [Homo sapiens] 303 5e-82
gi|29789445 desmoglein 4 isoform 2 [Homo sapiens] 295 1e-79
gi|116534898 desmoglein 2 preproprotein [Homo sapiens] 294 3e-79
>gi|4757960 cadherin 1, type 1 preproprotein [Homo sapiens]
Length = 882
Score = 1786 bits (4625), Expect = 0.0
Identities = 882/882 (100%), Positives = 882/882 (100%)
Query: 1 MGPWSRSLSALLLLLQVSSWLCQEPEPCHPGFDAESYTFTVPRRHLERGRVLGRVNFEDC 60
MGPWSRSLSALLLLLQVSSWLCQEPEPCHPGFDAESYTFTVPRRHLERGRVLGRVNFEDC
Sbjct: 1 MGPWSRSLSALLLLLQVSSWLCQEPEPCHPGFDAESYTFTVPRRHLERGRVLGRVNFEDC 60
Query: 61 TGRQRTAYFSLDTRFKVGTDGVITVKRPLRFHNPQIHFLVYAWDSTYRKFSTKVTLNTVG 120
TGRQRTAYFSLDTRFKVGTDGVITVKRPLRFHNPQIHFLVYAWDSTYRKFSTKVTLNTVG
Sbjct: 61 TGRQRTAYFSLDTRFKVGTDGVITVKRPLRFHNPQIHFLVYAWDSTYRKFSTKVTLNTVG 120
Query: 121 HHHRPPPHQASVSGIQAELLTFPNSSPGLRRQKRDWVIPPISCPENEKGPFPKNLVQIKS 180
HHHRPPPHQASVSGIQAELLTFPNSSPGLRRQKRDWVIPPISCPENEKGPFPKNLVQIKS
Sbjct: 121 HHHRPPPHQASVSGIQAELLTFPNSSPGLRRQKRDWVIPPISCPENEKGPFPKNLVQIKS 180
Query: 181 NKDKEGKVFYSITGQGADTPPVGVFIIERETGWLKVTEPLDRERIATYTLFSHAVSSNGN 240
NKDKEGKVFYSITGQGADTPPVGVFIIERETGWLKVTEPLDRERIATYTLFSHAVSSNGN
Sbjct: 181 NKDKEGKVFYSITGQGADTPPVGVFIIERETGWLKVTEPLDRERIATYTLFSHAVSSNGN 240
Query: 241 AVEDPMEILITVTDQNDNKPEFTQEVFKGSVMEGALPGTSVMEVTATDADDDVNTYNAAI 300
AVEDPMEILITVTDQNDNKPEFTQEVFKGSVMEGALPGTSVMEVTATDADDDVNTYNAAI
Sbjct: 241 AVEDPMEILITVTDQNDNKPEFTQEVFKGSVMEGALPGTSVMEVTATDADDDVNTYNAAI 300
Query: 301 AYTILSQDPELPDKNMFTINRNTGVISVVTTGLDRESFPTYTLVVQAADLQGEGLSTTAT 360
AYTILSQDPELPDKNMFTINRNTGVISVVTTGLDRESFPTYTLVVQAADLQGEGLSTTAT
Sbjct: 301 AYTILSQDPELPDKNMFTINRNTGVISVVTTGLDRESFPTYTLVVQAADLQGEGLSTTAT 360
Query: 361 AVITVTDTNDNPPIFNPTTYKGQVPENEANVVITTLKVTDADAPNTPAWEAVYTILNDDG 420
AVITVTDTNDNPPIFNPTTYKGQVPENEANVVITTLKVTDADAPNTPAWEAVYTILNDDG
Sbjct: 361 AVITVTDTNDNPPIFNPTTYKGQVPENEANVVITTLKVTDADAPNTPAWEAVYTILNDDG 420
Query: 421 GQFVVTTNPVNNDGILKTAKGLDFEAKQQYILHVAVTNVVPFEVSLTTSTATVTVDVLDV 480
GQFVVTTNPVNNDGILKTAKGLDFEAKQQYILHVAVTNVVPFEVSLTTSTATVTVDVLDV
Sbjct: 421 GQFVVTTNPVNNDGILKTAKGLDFEAKQQYILHVAVTNVVPFEVSLTTSTATVTVDVLDV 480
Query: 481 NEAPIFVPPEKRVEVSEDFGVGQEITSYTAQEPDTFMEQKITYRIWRDTANWLEINPDTG 540
NEAPIFVPPEKRVEVSEDFGVGQEITSYTAQEPDTFMEQKITYRIWRDTANWLEINPDTG
Sbjct: 481 NEAPIFVPPEKRVEVSEDFGVGQEITSYTAQEPDTFMEQKITYRIWRDTANWLEINPDTG 540
Query: 541 AISTRAELDREDFEHVKNSTYTALIIATDNGSPVATGTGTLLLILSDVNDNAPIPEPRTI 600
AISTRAELDREDFEHVKNSTYTALIIATDNGSPVATGTGTLLLILSDVNDNAPIPEPRTI
Sbjct: 541 AISTRAELDREDFEHVKNSTYTALIIATDNGSPVATGTGTLLLILSDVNDNAPIPEPRTI 600
Query: 601 FFCERNPKPQVINIIDADLPPNTSPFTAELTHGASANWTIQYNDPTQESIILKPKMALEV 660
FFCERNPKPQVINIIDADLPPNTSPFTAELTHGASANWTIQYNDPTQESIILKPKMALEV
Sbjct: 601 FFCERNPKPQVINIIDADLPPNTSPFTAELTHGASANWTIQYNDPTQESIILKPKMALEV 660
Query: 661 GDYKINLKLMDNQNKDQVTTLEVSVCDCEGAAGVCRKAQPVEAGLQIPAILGILGGILAL 720
GDYKINLKLMDNQNKDQVTTLEVSVCDCEGAAGVCRKAQPVEAGLQIPAILGILGGILAL
Sbjct: 661 GDYKINLKLMDNQNKDQVTTLEVSVCDCEGAAGVCRKAQPVEAGLQIPAILGILGGILAL 720
Query: 721 LILILLLLLFLRRRAVVKEPLLPPEDDTRDNVYYYDEEGGGEEDQDFDLSQLHRGLDARP 780
LILILLLLLFLRRRAVVKEPLLPPEDDTRDNVYYYDEEGGGEEDQDFDLSQLHRGLDARP
Sbjct: 721 LILILLLLLFLRRRAVVKEPLLPPEDDTRDNVYYYDEEGGGEEDQDFDLSQLHRGLDARP 780
Query: 781 EVTRNDVAPTLMSVPRYLPRPANPDEIGNFIDENLKAADTDPTAPPYDSLLVFDYEGSGS 840
EVTRNDVAPTLMSVPRYLPRPANPDEIGNFIDENLKAADTDPTAPPYDSLLVFDYEGSGS
Sbjct: 781 EVTRNDVAPTLMSVPRYLPRPANPDEIGNFIDENLKAADTDPTAPPYDSLLVFDYEGSGS 840
Query: 841 EAASLSSLNSSESDKDQDYDYLNEWGNRFKKLADMYGGGEDD 882
EAASLSSLNSSESDKDQDYDYLNEWGNRFKKLADMYGGGEDD
Sbjct: 841 EAASLSSLNSSESDKDQDYDYLNEWGNRFKKLADMYGGGEDD 882
>gi|14589891 cadherin 3, type 1 preproprotein [Homo sapiens]
Length = 829
Score = 922 bits (2384), Expect = 0.0
Identities = 477/875 (54%), Positives = 594/875 (67%), Gaps = 56/875 (6%)
Query: 10 ALLLLLQVSSWLCQEPEPCHPGFDAESYTFTVPRRHLERGRVLGRVNFEDCTGRQRTAYF 69
A LLLLQV C EPC F T E G+ LG+V F C G++ +
Sbjct: 9 ASLLLLQVCWLQCAASEPCRAVFREAEVTLEAGGAEQEPGQALGKV-FMGCPGQEPALFS 67
Query: 70 SLDTRFKVGTDGVITVKRPLRFHNPQIHFLVYAWDSTYRKFSTKVTLNTVGHHHRPPPHQ 129
+ + F V + +R L+ NP
Sbjct: 68 TDNDDFTVRNGETVQERRSLKERNP----------------------------------- 92
Query: 130 ASVSGIQAELLTFPNSSPGLRRQKRDWVIPPISCPENEKGPFPKNLVQIKSNKDKEGKVF 189
L FP S LRR KRDWV+ PIS PEN KGPFP+ L Q+KSNKD++ K+F
Sbjct: 93 ---------LKIFP-SKRILRRHKRDWVVAPISVPENGKGPFPQRLNQLKSNKDRDTKIF 142
Query: 190 YSITGQGADTPPVGVFIIERETGWLKVTEPLDRERIATYTLFSHAVSSNGNAVEDPMEIL 249
YSITG GAD+PP GVF +E+ETGWL + +PLDRE IA Y LF HAVS NG +VEDPM I
Sbjct: 143 YSITGPGADSPPEGVFAVEKETGWLLLNKPLDREEIAKYELFGHAVSENGASVEDPMNIS 202
Query: 250 ITVTDQNDNKPEFTQEVFKGSVMEGALPGTSVMEVTATDADDDVNTYNAAIAYTILSQDP 309
I VTDQND+KP+FTQ+ F+GSV+EG LPGTSVM+VTATD DD + TYN +AY+I SQ+P
Sbjct: 203 IIVTDQNDHKPKFTQDTFRGSVLEGVLPGTSVMQVTATDEDDAIYTYNGVVAYSIHSQEP 262
Query: 310 ELPDKNMFTINRNTGVISVVTTGLDRESFPTYTLVVQAADLQGEGLSTTATAVITVTDTN 369
+ P MFTI+R+TG ISV+++GLDRE P YTL +QA D+ G+G +TTA AV+ + D N
Sbjct: 263 KDPHDLMFTIHRSTGTISVISSGLDREKVPEYTLTIQATDMDGDGSTTTAVAVVEILDAN 322
Query: 370 DNPPIFNPTTYKGQVPENEANVVITTLKVTDADAPNTPAWEAVYTIL-NDDGGQFVVTTN 428
DN P+F+P Y+ VPEN + L VTD DAPN+PAW A Y I+ DDG F +TT+
Sbjct: 323 DNAPMFDPQKYEAHVPENAVGHEVQRLTVTDLDAPNSPAWRATYLIMGGDDGDHFTITTH 382
Query: 429 PVNNDGILKTAKGLDFEAKQQYILHVAVTNVVPFEVSLTTSTATVTVDVLDVNEAPIFVP 488
P +N GIL T KGLDFEAK Q+ L+V VTN PF + L TSTAT+ V V DVNEAP+FVP
Sbjct: 383 PESNQGILTTRKGLDFEAKNQHTLYVEVTNEAPFVLKLPTSTATIVVHVEDVNEAPVFVP 442
Query: 489 PEKRVEVSEDFGVGQEITSYTAQEPDTFMEQKITYRIWRDTANWLEINPDTGAISTRAEL 548
P K VEV E G+ + YTA++PD QKI+YRI RD A WL ++PD+G ++ L
Sbjct: 443 PSKVVEVQEGIPTGEPVCVYTAEDPDK-ENQKISYRILRDPAGWLAMDPDSGQVTAVGTL 501
Query: 549 DREDFEHVKNSTYTALIIATDNGSPVATGTGTLLLILSDVNDNAPIPEPRTIFFCERNPK 608
DRED + V+N+ Y +++A DNGSP TGTGTLLL L DVND+ P+PEPR I C ++P
Sbjct: 502 DREDEQFVRNNIYEVMVLAMDNGSPPTTGTGTLLLTLIDVNDHGPVPEPRQITICNQSPV 561
Query: 609 PQVINIIDADLPPNTSPFTAELTHGASANWTIQYNDPTQESIILKPKMALEVGDYKINLK 668
QV+NI D DL P+TSPF A+LT + WT + N+ ++++L K L+ Y ++L
Sbjct: 562 RQVLNITDKDLSPHTSPFQAQLTDDSDIYWTAEVNE-EGDTVVLSLKKFLKQDTYDVHLS 620
Query: 669 LMDNQNKDQVTTLEVSVCDCEGAAGVCRKAQPVEAGLQIPAILGILGGILALLILILLLL 728
L D+ NK+Q+T + +VCDC G C P + G IL +LG +LALL L+L+LL
Sbjct: 621 LSDHGNKEQLTVIRATVCDCHGHVETC--PGPWKGGF----ILPVLGAVLALLFLLLVLL 674
Query: 729 LFLRRRAVVKEPLLPPEDDTRDNVYYYDEEGGGEEDQDFDLSQLHRGLDARPEVT-RNDV 787
L +R++ +KEPLL PEDDTRDNV+YY EEGGGEEDQD+D++QLHRGL+ARPEV RNDV
Sbjct: 675 LLVRKKRKIKEPLLLPEDDTRDNVFYYGEEGGGEEDQDYDITQLHRGLEARPEVVLRNDV 734
Query: 788 APTLMSVPRYLPRPANPDEIGNFIDENLKAADTDPTAPPYDSLLVFDYEGSGSEAASLSS 847
APT++ P Y PRPANPDEIGNFI ENLKAA+TDPTAPPYD+LLVFDYEGSGS+AASLSS
Sbjct: 735 APTIIPTPMYRPRPANPDEIGNFIIENLKAANTDPTAPPYDTLLVFDYEGSGSDAASLSS 794
Query: 848 LNSSESDKDQDYDYLNEWGNRFKKLADMYGGGEDD 882
L SS SD+DQDYDYLNEWG+RFKKLADMYGGGEDD
Sbjct: 795 LTSSASDQDQDYDYLNEWGSRFKKLADMYGGGEDD 829
>gi|14589889 cadherin 2, type 1 preproprotein [Homo sapiens]
Length = 906
Score = 736 bits (1900), Expect = 0.0
Identities = 426/906 (47%), Positives = 555/906 (61%), Gaps = 43/906 (4%)
Query: 8 LSALLLLLQVSSWLCQEPEPCHPGFDAESYTFTVPRRHLERGRVLGRVNFEDCTGRQRTA 67
L L LLQ S E C GF + Y+ V + + G+ L V F +C G+++
Sbjct: 12 LPLLAALLQASVEASGEIALCKTGFPEDVYS-AVLSKDVHEGQPLLNVKFSNCNGKRKVQ 70
Query: 68 YFSLDTR-FKVGTDGVITVKRPLRFHNPQIHFLVYAWDS-TYRKFSTKVTLNTVGHHHRP 125
Y S + FKV DG++ R + FL+YA D T K+ V L+ +P
Sbjct: 71 YESSEPADFKVDEDGMVYAVRSFPLSSEHAKFLIYAQDKETQEKWQVAVKLSL-----KP 125
Query: 126 PPHQASVS-GIQAELLTFPNS----SPGLRRQKRDWVIPPISCPENEKGPFPKNLVQIKS 180
+ SV + E + FP S L+RQKRDWVIPPI+ PEN +GPFP+ LV+I+S
Sbjct: 126 TLTEESVKESAEVEEIVFPRQFSKHSGHLQRQKRDWVIPPINLPENSRGPFPQELVRIRS 185
Query: 181 NKDKEGKVFYSITGQGADTPPVGVFIIERETGWLKVTEPLDRERIATYTLFSHAVSSNGN 240
++DK + YS+TG GAD PP G+FII +G L VT+PLDRE+IA + L +HAV NGN
Sbjct: 186 DRDKNLSLRYSVTGPGADQPPTGIFIINPISGQLSVTKPLDREQIARFHLRAHAVDINGN 245
Query: 241 AVEDPMEILITVTDQNDNKPEFTQEVFKGSVMEGALPGTSVMEVTATDADDDVNTYNAAI 300
VE+P++I+I V D NDN+PEF +V+ G+V EG+ PGT VM VTA DADD N N +
Sbjct: 246 QVENPIDIVINVIDMNDNRPEFLHQVWNGTVPEGSKPGTYVMTVTAIDADDP-NALNGML 304
Query: 301 AYTILSQDPELPDKNMFTINRNTGVISVVTTGLDRESFPTYTLVVQAADLQGE---GLST 357
Y I+SQ P P NMFTIN TG I V GLDRE YTL++QA D++G GLS
Sbjct: 305 RYRIVSQAPSTPSPNMFTINNETGDIITVAAGLDREKVQQYTLIIQATDMEGNPTYGLSN 364
Query: 358 TATAVITVTDTNDNPPIFNPTTYKGQVPENEANVVITTLKVTDADAPNTPAWEAVYTIL- 416
TATAVITVTD NDNPP F T+ G+VPEN ++++ L VTD D P+TPAW AVY I
Sbjct: 365 TATAVITVTDVNDNPPEFTAMTFYGEVPENRVDIIVANLTVTDKDQPHTPAWNAVYRISG 424
Query: 417 NDDGGQFVVTTNPVNNDGILKTAKGLDFEAKQQYILHVAVTNVVPFEVSL---TTSTATV 473
D G+F + T+P +NDG++ K +DFE + ++L VA N VP + STATV
Sbjct: 425 GDPTGRFAIQTDPNSNDGLVTVVKPIDFETNRMFVLTVAAENQVPLAKGIQHPPQSTATV 484
Query: 474 TVDVLDVNEAPIFVPPEKRVEVSEDFGVGQEITSYTAQEPDTFMEQKITYRIWRDTANWL 533
+V V+DVNE P F P K + E G +T++TAQ+PD +M+Q I Y D ANWL
Sbjct: 485 SVTVIDVNENPYFAPNPKIIRQEEGLHAGTMLTTFTAQDPDRYMQQNIRYTKLSDPANWL 544
Query: 534 EINPDTGAISTRAELDREDFEHVKNSTYTALIIATDNGSPVATGTGTLLLILSDVNDNAP 593
+I+P G I+T A LDRE +VKN+ Y A +A+DNG P +GTGTL + L D+NDNAP
Sbjct: 545 KIDPVNGQITTIAVLDRES-PNVKNNIYNATFLASDNGIPPMSGTGTLQIYLLDINDNAP 603
Query: 594 IPEPRTIFFCERNPKPQVINI--IDADLPPNTSPFTAELTHG---ASANWTIQYNDPTQE 648
P+ CE P P INI +D D+ PN PF +L NWTI +
Sbjct: 604 QVLPQEAETCE-TPDPNSINITALDYDIDPNAGPFAFDLPLSPVTIKRNWTITRLNGDFA 662
Query: 649 SIILKPKMALEVGDYKINLKLMDNQN--KDQVTTLEVSVCDCEGAAGVCRKAQPVEAGLQ 706
+ LK K LE G Y++ + + D+ N K ++ L V VC C+ + V AGL
Sbjct: 663 QLNLKIKF-LEAGIYEVPIIITDSGNPPKSNISILRVKVCQCDSNGDCTDVDRIVGAGLG 721
Query: 707 IPAILGILGGILALLILILLLLLFLRRR---AVVKEPLLPPEDDTRDNVYYYDEEGGGEE 763
AI+ IL I+ LLIL+L+ +++++RR K+ L+ PEDD RDN+ YDEEGGGEE
Sbjct: 722 TGAIIAILLCIIILLILVLMFVVWMKRRDKERQAKQLLIDPEDDVRDNILKYDEEGGGEE 781
Query: 764 DQDFDLSQLHRGLDARPE------VTRNDVAPTLMSVPRYLPRPA--NPDEIGNFIDENL 815
DQD+DLSQL + P+ + R D P + + P+Y R A +P +IG+FI+E L
Sbjct: 782 DQDYDLSQLQQPDTVEPDAIKPVGIRRMDERP-IHAEPQYPVRSAAPHPGDIGDFINEGL 840
Query: 816 KAADTDPTAPPYDSLLVFDYEGSGSEAASLSSLNSSESDKDQDYDYLNEWGNRFKKLADM 875
KAAD DPTAPPYDSLLVFDYEGSGS A SLSSLNSS S +QDYDYLN+WG RFKKLADM
Sbjct: 841 KAADNDPTAPPYDSLLVFDYEGSGSTAGSLSSLNSSSSGGEQDYDYLNDWGPRFKKLADM 900
Query: 876 YGGGED 881
YGGG+D
Sbjct: 901 YGGGDD 906
>gi|14589893 cadherin 4, type 1 preproprotein [Homo sapiens]
Length = 916
Score = 712 bits (1838), Expect = 0.0
Identities = 419/916 (45%), Positives = 553/916 (60%), Gaps = 51/916 (5%)
Query: 11 LLLLLQVSSWL------CQEPEPCHPGFDAESYTFTVPRRHLERGRVLGRVNFEDCTGRQ 64
LLLLL +S L E C GF + YT + + LE G L +V F C G +
Sbjct: 8 LLLLLSLSGALRAHNEDLTTRETCKAGFSEDDYTALISQNILE-GEKLLQVKFSSCVGTK 66
Query: 65 RTAYFSLDTRFKVGTDGVITVKRPLRFHNPQIHFLVYAWDS-TYRKFSTKVTL---NTVG 120
T Y + FKVG DG + R L+ + Q+ F V AWDS T K+ V L T
Sbjct: 67 GTQYETNSMDFKVGADGTVFATRELQVPSEQVAFTVTAWDSQTAEKWDAVVRLLVAQTSS 126
Query: 121 HH--HRPPPHQASVS-----GIQAELLTFPN--SSPGLRRQKRDWVIPPISCPENEKGPF 171
H H+P + V+ + LL +P ++ GLRR+KRDWVIPPI+ PEN +GPF
Sbjct: 127 PHSGHKPQKGKKVVALDPSPPPKDTLLPWPQHQNANGLRRRKRDWVIPPINVPENSRGPF 186
Query: 172 PKNLVQIKSNKDKEGKVFYSITGQGADTPPVGVFIIERETGWLKVTEPLDRERIATYTLF 231
P+ LV+I+S+KD + + YSITG GAD PP+ VF I+ +G + VT P+DRE A+Y L
Sbjct: 187 PQQLVRIRSDKDNDIPIRYSITGVGADQPPMEVFSIDSMSGRMYVTRPMDREEHASYHLR 246
Query: 232 SHAVSSNGNAVEDPMEILITVTDQNDNKPEFTQEVFKGSVMEGALPGTSVMEVTATDADD 291
+HAV NGN VE+P+++ I V D NDN+PEF +V+ GSV EG+ PGT VM VTA DADD
Sbjct: 247 AHAVDMNGNKVENPIDLYIYVIDMNDNRPEFINQVYNGSVDEGSKPGTYVMTVTANDADD 306
Query: 292 DVNTYNAAIAYTILSQDPELPDKNMFTINRNTGVISVVTTGLDRESFPTYTLVVQAADLQ 351
T N + Y I++Q P+ P +NMFTIN TG I V GLDRE YT++VQA D++
Sbjct: 307 S-TTANGMVRYRIVTQTPQSPSQNMFTINSETGDIVTVAAGLDREKVQQYTVIVQATDME 365
Query: 352 GE---GLSTTATAVITVTDTNDNPPIFNPTTYKGQVPENEANVVITTLKVTDADAPNTPA 408
G GLS TATA+ITVTD NDNPP F +T+ G+VPEN V+ L V D D P++P
Sbjct: 366 GNLNYGLSNTATAIITVTDVNDNPPEFTASTFAGEVPENRVETVVANLTVMDRDQPHSPN 425
Query: 409 WEAVYTILN-DDGGQFVVTTNPVNNDGILKTAKGLDFEAKQQYILHVAVTNVVPFEVSLT 467
W AVY I++ D G F V T+PV N+G++ K +D+E + ++L V V+N P +
Sbjct: 426 WNAVYRIISGDPSGHFSVRTDPVTNEGMVTVVKAVDYELNRAFMLTVMVSNQAPLASGIQ 485
Query: 468 ---TSTATVTVDVLDVNEAPIFVPPEKRVEVSEDFGVGQEITSYTAQEPDTFMEQKITYR 524
STA VT+ ++D+NEAP F K + + E G +T+++A +PD FM+Q + Y
Sbjct: 486 MSFQSTAGVTISIMDINEAPYFPSNHKLIRLEEGVPPGTVLTTFSAVDPDRFMQQAVRYS 545
Query: 525 IWRDTANWLEINPDTGAISTRAELDREDFEHVKNSTYTALIIATDNGSPVATGTGTLLLI 584
D A+WL IN G I+T A LDRE + KN+ Y A +A DNG P A+GTGTL +
Sbjct: 546 KLSDPASWLHINATNGQITTAAVLDRESL-YTKNNVYEATFLAADNGIPPASGTGTLQIY 604
Query: 585 LSDVNDNAPIPEPRTIFFCERNPKPQVINI--IDADLPPNTSPFTAELTHGASA---NWT 639
L D+NDNAP P+ CE+ P INI DAD+ PN P+ EL +A NWT
Sbjct: 605 LIDINDNAPELLPKEAQICEK-PNLNAINITAADADVDPNIGPYVFELPFVPAAVRKNWT 663
Query: 640 IQYNDPTQESIILKPKMALEVGDYKINLKLMDNQNK--DQVTTLEVSVCDCEGAAGVCRK 697
I + + L+ + LE G Y + + + D+ N + ++V VC C+
Sbjct: 664 ITRLNGDYAQLSLR-ILYLEAGMYDVPIIVTDSGNPPLSNTSIIKVKVCPCDDNGDCTTI 722
Query: 698 AQPVEAGLQIPAILGILGGILALLILILLLLLFLRRRAV---VKEPLLPPEDDTRDNVYY 754
AGL AI+ IL IL LL ++LL +++++RR K+ L+ PEDD RDN+
Sbjct: 723 GAVAAAGLGTGAIVAILICILILLTMVLLFVMWMKRREKERHTKQLLIDPEDDVRDNILK 782
Query: 755 YDEEGGGEEDQDFDLSQLHRG------LDARPEVTRNDVAPTLMSVPRYLPRP--ANPDE 806
YDEEGGGEEDQD+DLSQL + P V R D P + + P+Y RP +P +
Sbjct: 783 YDEEGGGEEDQDYDLSQLQQPEAMGHVPSKAPGVRRVDERP-VGAEPQYPIRPMVPHPGD 841
Query: 807 IGNFIDENLKAADTDPTAPPYDSLLVFDYEGSGSEAASLSSLNSSESDKDQDYDYLNEWG 866
IG+FI+E L+AAD DPTAPPYDSLLVFDYEGSGS A S+SSLNSS S DQDYDYLN+WG
Sbjct: 842 IGDFINEGLRAADNDPTAPPYDSLLVFDYEGSGSTAGSVSSLNSSSSG-DQDYDYLNDWG 900
Query: 867 NRFKKLADMYGGGEDD 882
RFKKLADMYGGGE+D
Sbjct: 901 PRFKKLADMYGGGEED 916
>gi|4826669 cadherin 15 preproprotein [Homo sapiens]
Length = 814
Score = 496 bits (1277), Expect = e-140
Identities = 309/761 (40%), Positives = 440/761 (57%), Gaps = 45/761 (5%)
Query: 146 SPGLRRQKRDWVIPPISCPENEKG-PFPKNLVQIKSNKDKEGKVFYSITGQGADTPPVGV 204
+P L R +R WVIPPIS EN K P+P LVQIKS+K + G V YSI G G D P GV
Sbjct: 37 APALSRVRRAWVIPPISVSENHKRLPYP--LVQIKSDKQQLGSVIYSIQGPGVDEEPRGV 94
Query: 205 FIIERETGWLKVTEPLDRERIATYTLFSHAVSSNGNAVEDPMEILITVTDQNDNKPEFTQ 264
F I++ TG + + LDRE+ + L + A+ G+ +EDP ++ I V DQNDN+P F Q
Sbjct: 95 FSIDKFTGKVFLNAMLDREKTDRFRLRAFALDLGGSTLEDPTDLEIVVVDQNDNRPAFLQ 154
Query: 265 EVFKGSVMEGALPGTSVMEVTATDADDDVNTYNAAIAYTILSQ-DPELPDKNMFTINRNT 323
E F G V+EGA+PGT V ATDADD T NAA+ ++IL Q PEL F+I+ T
Sbjct: 155 EAFTGRVLEGAVPGTYVTRAEATDADDP-ETDNAALRFSILQQGSPEL-----FSIDELT 208
Query: 324 GVISVVTTGLDRESFPTYTLVVQAADLQGEGLSTTATAVITVTDTNDNPPIFNPTTYKGQ 383
G I V GLDRE Y L +Q AD+ G+GL+ TA+A+IT+ D NDN P F + +
Sbjct: 209 GEIRTVQVGLDREVVAVYNLTLQVADMSGDGLTATASAIITLDDINDNAPEFTRDEFFME 268
Query: 384 VPENEANVVITTLKVTDADAPNTPAWEAVYTIL-NDDGGQFVVTTNPVNNDGILKTAKGL 442
E + V + L+V D D P +P W A +TIL D GQF + T+P N+G+L K L
Sbjct: 269 AIEAVSGVDVGRLEVEDRDLPGSPNWVARFTILEGDPDGQFTIRTDPKTNEGVLSIVKAL 328
Query: 443 DFEAKQQYILHVAVTNVVPFEVSLTTS---TATVTVDVLDVNEAPIFVPPEKRVEVSEDF 499
D+E+ + Y L V+V N P + + + A V V V D NE P+F R ++E
Sbjct: 329 DYESCEHYELKVSVQNEAPLQAAALRAERGQAKVRVHVQDTNEPPVFQENPLRTSLAEGA 388
Query: 500 GVGQEITSYTAQEPDTFMEQKITYRIWRDTANWLEINPDTGAISTRAELDREDFEHVKNS 559
G + +++A++PDT Q+++Y D +WL+++ TG I T+ L +K
Sbjct: 389 PPGTLVATFSARDPDTEQLQRLSYSKDYDPEDWLQVDAATGRIQTQHVLSPAS-PFLKGG 447
Query: 560 TYTALIIATDNGSPVATGTGTLLLILSDVNDNAPI--PEPRTIFFCERNPKP-QVINIID 616
Y A+++A D+ S T TGTL + + +VND+AP+ P P E + P ++ D
Sbjct: 448 WYRAIVLAQDDASQPRTATGTLSIEILEVNDHAPVLAPPPPGSLCSEPHQGPGLLLGATD 507
Query: 617 ADLPPNTSPFTAELT---HGASANWTIQYNDPTQESIILKPKMALEVGDYKINLKLMDN- 672
DLPP+ +PF +L+ NW++ + + L+P+ + G ++++L L D+
Sbjct: 508 EDLPPHGAPFHFQLSPRLPELGRNWSLSQVNVSHAR--LRPRHQVPEGLHRLSLLLRDSG 565
Query: 673 ---QNKDQVTTLEVSVCDCEGAAGVCRKAQPV----EAGLQIPAILGILGGILALLILIL 725
Q ++Q L V+VC C G GVC GL + A++ +L L LL+L+L
Sbjct: 566 QPPQQREQ--PLNVTVCRC-GKDGVCLPGAAALLAGGTGLSLGALVIVLASALLLLVLVL 622
Query: 726 LLLLFLR--RRAVVKEPLLPPEDDTRDNVYYYDEEGGGEEDQD-FDLSQLHR----GLDA 778
L+ L R +++ K L P+DD RDNV YDE+GGGEEDQD +D+SQL L
Sbjct: 623 LVALRARFWKQSRGKGLLHGPQDDLRDNVLNYDEQGGGEEDQDAYDISQLRHPTALSLPL 682
Query: 779 RPEVTRNDVAPTLM--SVPRYLPRPANPDEIGNFIDENLKAADTDPTAPPYDSLLVFDYE 836
P R D + PR L P +P +I +FI++ L+AAD+DP+ PPYD+ L++DYE
Sbjct: 683 GPPPLRRDAPQGRLHPQPPRVL--PTSPLDIADFINDGLEAADSDPSVPPYDTALIYDYE 740
Query: 837 GSGSEAASLSSLNSSESDKDQDYDYLNEWGNRFKKLADMYG 877
G GS A +LSS+ SS+ D+DQDYDYL +WG RF +LADMYG
Sbjct: 741 GDGSVAGTLSSILSSQGDEDQDYDYLRDWGPRFARLADMYG 781
>gi|16306487 cadherin 7, type 2 preproprotein [Homo sapiens]
Length = 785
Score = 405 bits (1042), Expect = e-113
Identities = 293/787 (37%), Positives = 423/787 (53%), Gaps = 65/787 (8%)
Query: 133 SGIQAELLTFPNSSP----GLRRQKRDWVIPPISCPENEKGPFPKNLVQIKSNKDK-EGK 187
SG+ L+ S P G R KR WV E G P + ++ S+ DK +G
Sbjct: 22 SGMSQAELSRSRSKPYFQSGRSRTKRSWVWNQFFVLEEYMGSDPLYVGKLHSDVDKGDGS 81
Query: 188 VFYSITGQGADTPPVGVFIIERETGWLKVTEPLDRERIATYTLFSHAVSSNGNA-VEDPM 246
+ Y ++G+GA + +FII+ TG + T+ LDRE A YTL + A+ N VE
Sbjct: 82 IKYILSGEGASS----IFIIDENTGDIHATKRLDREEQAYYTLRAQALDRLTNKPVEPES 137
Query: 247 EILITVTDQNDNKPEFTQEVFKGSVMEGALPGTSVMEVTATDADDDVNTYNAAIAYTILS 306
E +I + D NDN+P+F + V E + GTSV++VTATDADD +A + Y+IL
Sbjct: 138 EFVIKIQDINDNEPKFLDGPYTAGVPEMSPVGTSVVQVTATDADDPTYGNSARVVYSILQ 197
Query: 307 QDPELPDKNMFTINRNTGVISVVTTGLDRESFPTYTLVVQAADLQGE--GLSTTATAVIT 364
P F++ TGVI +DRE+ Y LV+QA D+ G+ GLS T + +T
Sbjct: 198 GQP------YFSVEPKTGVIKTALPNMDREAKDQYLLVIQAKDMVGQNGGLSGTTSVTVT 251
Query: 365 VTDTNDNPPIFNPTTYKGQVPEN-EANVVITTLKVTDADAPNTPAWEAVYTILNDDG-GQ 422
+TD NDNPP F +Y+ VPE+ V+ +K DAD E Y I++ DG G
Sbjct: 252 LTDVNDNPPRFPRRSYQYNVPESLPVASVVARIKAADADIGANAEME--YKIVDGDGLGI 309
Query: 423 FVVTTNPVNNDGILKTAKGLDFEAKQQYILHVAVTN--VVPFEVSLT--TSTATVTVDVL 478
F ++ + +GI+ K LDFEAK Y L + N P +SL + T TV + V
Sbjct: 310 FKISVDKETQEGIITIQKELDFEAKTSYTLRIEAANKDADPRFLSLGPFSDTTTVKIIVE 369
Query: 479 DVNEAPIFVPPEKRVEVSEDFGVGQEITSYTAQEPDTFMEQKITYRIWRDT--ANWLEIN 536
DV+E P+F P +EVSE VG I + A +PD+ + Y I R+T + I+
Sbjct: 370 DVDEPPVFSSPLYPMEVSEATQVGNIIGTVAAHDPDS-SNSPVRYSIDRNTDLERYFNID 428
Query: 537 PDTGAISTRAELDREDFEHVKNSTYTALIIATDNGSPVATGTGTLLLILSDVNDNAP--- 593
++G I+T LDRE N+ + ++A ++ +P G G + + + D+NDNAP
Sbjct: 429 ANSGVITTAKSLDRET-----NAIHNITVLAMESQNPSQVGRGYVAITILDINDNAPEFA 483
Query: 594 IPEPRTIFFCERNPKPQVI---NIIDADLPPNTSPFTAELTHGASAN--WTIQYNDPTQE 648
+ T+ CE QVI + +D D P N F LT A+ N ++++ N
Sbjct: 484 MDYETTV--CENAQPGQVIQKISAVDKDEPSNGHQFYFSLTTDATNNHNFSLKDNKDNTA 541
Query: 649 SIILKPK--MALEVGDYKINLKLMDNQNKD--QVTTLEVSVCDCE--GAAGVCR-KAQPV 701
SI+ + E Y + + ++D+ + TL + VCDC+ G A C +A +
Sbjct: 542 SILTRRNGFRRQEQSVYYLPIFIVDSGSPSLSSTNTLTIRVCDCDADGVAQTCNAEAYVL 601
Query: 702 EAGLQIPAILGILGGILALLILILLLLLFLRRRAVVKEPLLPPED-DTRDNVYYYDEEGG 760
AGL A++ IL +L LL+LILL++ RR+ KEPL+ E+ D R+N+ YD+EGG
Sbjct: 602 PAGLSTGALIAILACVLTLLVLILLIVTMRRRK---KEPLIFDEERDIRENIVRYDDEGG 658
Query: 761 GEEDQD-FDLSQLHRGLDARPEVTRNDVAPTLMSVPRYLPRPAN---PDEI--GNFIDEN 814
GEED + FD++ L R TR DV P + ++L RPA PD + FI E
Sbjct: 659 GEEDTEAFDMAALRNLNVIRDTKTRRDVTPEI----QFLSRPAFKSIPDNVIFREFIWER 714
Query: 815 LKAADTDPTAPPYDSLLVFDYEGSGSEAASLSSLNSSESDKDQDYDYLNEWGNRFKKLAD 874
LK AD DP APPYDSL + +EG+GS A SLSSL+S S+ DQ+YDYL++WG RFK+LAD
Sbjct: 715 LKEADVDPGAPPYDSLQTYAFEGNGSVAESLSSLDSISSNSDQNYDYLSDWGPRFKRLAD 774
Query: 875 MYGGGED 881
MYG G++
Sbjct: 775 MYGTGQE 781
>gi|16306489 cadherin 7, type 2 preproprotein [Homo sapiens]
Length = 785
Score = 405 bits (1042), Expect = e-113
Identities = 293/787 (37%), Positives = 423/787 (53%), Gaps = 65/787 (8%)
Query: 133 SGIQAELLTFPNSSP----GLRRQKRDWVIPPISCPENEKGPFPKNLVQIKSNKDK-EGK 187
SG+ L+ S P G R KR WV E G P + ++ S+ DK +G
Sbjct: 22 SGMSQAELSRSRSKPYFQSGRSRTKRSWVWNQFFVLEEYMGSDPLYVGKLHSDVDKGDGS 81
Query: 188 VFYSITGQGADTPPVGVFIIERETGWLKVTEPLDRERIATYTLFSHAVSSNGNA-VEDPM 246
+ Y ++G+GA + +FII+ TG + T+ LDRE A YTL + A+ N VE
Sbjct: 82 IKYILSGEGASS----IFIIDENTGDIHATKRLDREEQAYYTLRAQALDRLTNKPVEPES 137
Query: 247 EILITVTDQNDNKPEFTQEVFKGSVMEGALPGTSVMEVTATDADDDVNTYNAAIAYTILS 306
E +I + D NDN+P+F + V E + GTSV++VTATDADD +A + Y+IL
Sbjct: 138 EFVIKIQDINDNEPKFLDGPYTAGVPEMSPVGTSVVQVTATDADDPTYGNSARVVYSILQ 197
Query: 307 QDPELPDKNMFTINRNTGVISVVTTGLDRESFPTYTLVVQAADLQGE--GLSTTATAVIT 364
P F++ TGVI +DRE+ Y LV+QA D+ G+ GLS T + +T
Sbjct: 198 GQP------YFSVEPKTGVIKTALPNMDREAKDQYLLVIQAKDMVGQNGGLSGTTSVTVT 251
Query: 365 VTDTNDNPPIFNPTTYKGQVPEN-EANVVITTLKVTDADAPNTPAWEAVYTILNDDG-GQ 422
+TD NDNPP F +Y+ VPE+ V+ +K DAD E Y I++ DG G
Sbjct: 252 LTDVNDNPPRFPRRSYQYNVPESLPVASVVARIKAADADIGANAEME--YKIVDGDGLGI 309
Query: 423 FVVTTNPVNNDGILKTAKGLDFEAKQQYILHVAVTN--VVPFEVSLT--TSTATVTVDVL 478
F ++ + +GI+ K LDFEAK Y L + N P +SL + T TV + V
Sbjct: 310 FKISVDKETQEGIITIQKELDFEAKTSYTLRIEAANKDADPRFLSLGPFSDTTTVKIIVE 369
Query: 479 DVNEAPIFVPPEKRVEVSEDFGVGQEITSYTAQEPDTFMEQKITYRIWRDT--ANWLEIN 536
DV+E P+F P +EVSE VG I + A +PD+ + Y I R+T + I+
Sbjct: 370 DVDEPPVFSSPLYPMEVSEATQVGNIIGTVAAHDPDS-SNSPVRYSIDRNTDLERYFNID 428
Query: 537 PDTGAISTRAELDREDFEHVKNSTYTALIIATDNGSPVATGTGTLLLILSDVNDNAP--- 593
++G I+T LDRE N+ + ++A ++ +P G G + + + D+NDNAP
Sbjct: 429 ANSGVITTAKSLDRET-----NAIHNITVLAMESQNPSQVGRGYVAITILDINDNAPEFA 483
Query: 594 IPEPRTIFFCERNPKPQVI---NIIDADLPPNTSPFTAELTHGASAN--WTIQYNDPTQE 648
+ T+ CE QVI + +D D P N F LT A+ N ++++ N
Sbjct: 484 MDYETTV--CENAQPGQVIQKISAVDKDEPSNGHQFYFSLTTDATNNHNFSLKDNKDNTA 541
Query: 649 SIILKPK--MALEVGDYKINLKLMDNQNKD--QVTTLEVSVCDCE--GAAGVCR-KAQPV 701
SI+ + E Y + + ++D+ + TL + VCDC+ G A C +A +
Sbjct: 542 SILTRRNGFRRQEQSVYYLPIFIVDSGSPSLSSTNTLTIRVCDCDADGVAQTCNAEAYVL 601
Query: 702 EAGLQIPAILGILGGILALLILILLLLLFLRRRAVVKEPLLPPED-DTRDNVYYYDEEGG 760
AGL A++ IL +L LL+LILL++ RR+ KEPL+ E+ D R+N+ YD+EGG
Sbjct: 602 PAGLSTGALIAILACVLTLLVLILLIVTMRRRK---KEPLIFDEERDIRENIVRYDDEGG 658
Query: 761 GEEDQD-FDLSQLHRGLDARPEVTRNDVAPTLMSVPRYLPRPAN---PDEI--GNFIDEN 814
GEED + FD++ L R TR DV P + ++L RPA PD + FI E
Sbjct: 659 GEEDTEAFDMAALRNLNVIRDTKTRRDVTPEI----QFLSRPAFKSIPDNVIFREFIWER 714
Query: 815 LKAADTDPTAPPYDSLLVFDYEGSGSEAASLSSLNSSESDKDQDYDYLNEWGNRFKKLAD 874
LK AD DP APPYDSL + +EG+GS A SLSSL+S S+ DQ+YDYL++WG RFK+LAD
Sbjct: 715 LKEADVDPGAPPYDSLQTYAFEGNGSVAESLSSLDSISSNSDQNYDYLSDWGPRFKRLAD 774
Query: 875 MYGGGED 881
MYG G++
Sbjct: 775 MYGTGQE 781
>gi|4502719 cadherin 13 preproprotein [Homo sapiens]
Length = 713
Score = 396 bits (1018), Expect = e-110
Identities = 258/716 (36%), Positives = 366/716 (51%), Gaps = 39/716 (5%)
Query: 12 LLLLQVSSWLCQEPEPCHPGFDAESYTFTVPRRHLERGRVLGRVNFEDCTGRQRTAYFSL 71
+LL QV E C PGF + + P +E +L + F DC G + Y
Sbjct: 11 VLLSQVLLLTSAEDLDCTPGFQQKVFHINQPAEFIEDQSILN-LTFSDCKGNDKLRYEVS 69
Query: 72 DTRFKVGTDGVITVKRPLRFHNPQIHFLVYAWDSTYRKFSTKVTLNTVGHHHRPPPHQAS 131
FKV +DG + R + + V+A + V +
Sbjct: 70 SPYFKVNSDGGLVALRNITAVGKTL--FVHARTPHAEDMAELVIVGG-----------KD 116
Query: 132 VSGIQAELLTFPNSSPGLRRQKRDWVIPPISCPENEKGPFPKNLVQIKSNKDKEGKVFYS 191
+ G ++ F +SP + RQKR V+ PI PEN++ PFP+++ ++ + D+ + +
Sbjct: 117 IQGSLQDIFKFARTSP-VPRQKRSIVVSPILIPENQRQPFPRDVGKVVDS-DRPERSKFR 174
Query: 192 ITGQGADTPPVGVFIIERETGWLKVTEPLDRERIATYTLFSHAVSSNGNAVEDPMEILIT 251
+TG+G D P G+F I TG + VT LDRE IA Y LF NG +E P+ + +
Sbjct: 175 LTGKGVDQEPKGIFRINENTGSVSVTRTLDREVIAVYQLFVETTDVNGKTLEGPVPLEVI 234
Query: 252 VTDQNDNKPEFTQEVFKGSVMEGALPGTSVMEVTATDADDDVNTYNAAIAYTILSQDPEL 311
V DQNDN+P F + + G VMEG+ GT+VM +TA DADD T NA + Y I Q P+
Sbjct: 235 VIDQNDNRPIFREGPYIGHVMEGSPTGTTVMRMTAFDADDPA-TDNALLRYNIRQQTPDK 293
Query: 312 PDKNMFTINRNTG-VISVVTTG-LDRESF--PTYTLVVQAADLQG--EGLSTTATAVITV 365
P NMF I+ G +++VV+ LDRE+ P Y L+++A D+ G GL+ TATA I +
Sbjct: 294 PSPNMFYIDPEKGDIVTVVSPALLDRETLENPKYELIIEAQDMAGLDVGLTGTATATIMI 353
Query: 366 TDTNDNPPIFNPTTYKGQVPENEANVVITTLKVTDADAPNTPAWEAVYTILNDDGGQ-FV 424
D ND+ P F ++ V E V++ L V D D P T AW A YTI+N + GQ F
Sbjct: 354 DDKNDHSPKFTKKEFQATVEEGAVGVIV-NLTVEDKDDPTTGAWRAAYTIINGNPGQSFE 412
Query: 425 VTTNPVNNDGILKTAKGLDFEAKQQYILHVAVTNVVPFEVSLT---TSTATVTVDVLDVN 481
+ TNP N+G+L K LD+E + L + V N P ++ +STATV + VLDVN
Sbjct: 413 IHTNPQTNEGMLSVVKPLDYEISAFHTLLIKVENEDPLVPDVSYGPSSTATVHITVLDVN 472
Query: 482 EAPIFVPPEKRVEVSEDFGVGQEITSYTAQEPDTFMEQKITYRIWRDTANWLEINPDTGA 541
E P+F P V ED VG + + A +PD+ Q I Y +++D A WL INP G
Sbjct: 473 EGPVFYPDPMMVTRQEDLSVGSVLLTVNATDPDSLQHQTIRYSVYKDPAGWLNINPINGT 532
Query: 542 ISTRAELDREDFEHVKNSTYTALIIATDNGSPVATGTGTLLLILSDVNDNAPIPEPRTIF 601
+ T A LDRE V NS YTAL +A D+G+P ATGTGTLL+ L DVNDNAP P
Sbjct: 533 VDTTAVLDRES-PFVDNSVYTALFLAIDSGNPPATGTGTLLITLEDVNDNAPFIYPTVAE 591
Query: 602 FCE--RNPKPQVINIIDADLPPNTSPFTAELTHGASAN--WTIQYNDPTQESIILKPKMA 657
C+ +N ++ D DL PNT PF E+ A + W I + T + L
Sbjct: 592 VCDDAKNLSVVILGASDKDLHPNTDPFKFEIHKQAVPDKVWKISKINNTHALVSLLQN-- 649
Query: 658 LEVGDYKINLKLMDNQN--KDQVTTLEVSVCDCEGAAGVCRKAQPVEAGLQIPAIL 711
L +Y + + + D+ +T L V VC C + C A + +P++L
Sbjct: 650 LNKANYNLPIMVTDSGKPPMTNITDLRVQVCSCRNSKVDCNAAGALR--FSLPSVL 703
>gi|4826673 cadherin 6, type 2 preproprotein [Homo sapiens]
Length = 790
Score = 393 bits (1010), Expect = e-109
Identities = 289/814 (35%), Positives = 418/814 (51%), Gaps = 60/814 (7%)
Query: 97 HFLVYAW-DSTYRKFSTKVTLNTVGHHHRPPPHQA-SVSGIQAELLTFPNSSPGLRRQKR 154
+FL+ W Y ST ++ T G P +A +SG NS L R KR
Sbjct: 6 YFLLLFWVGQPYPTLSTPLSKRTSGF---PAKKRALELSG---------NSKNELNRSKR 53
Query: 155 DWVIPPISCPENEKGPFPKNLVQIKSNKDK-EGKVFYSITGQGADTPPVGVFIIERETGW 213
W+ E G + + ++ S++D+ +G + Y ++G GA +FII TG
Sbjct: 54 SWMWNQFFLLEEYTGSDYQYVGKLHSDQDRGDGSLKYILSGDGAGD----LFIINENTGD 109
Query: 214 LKVTEPLDRERIATYTLFSHAVSSN-GNAVEDPMEILITVTDQNDNKPEFTQEVFKGSVM 272
++ T+ LDRE Y L + A++ G VE E +I + D NDN+P FT+EV+ +V
Sbjct: 110 IQATKRLDREEKPVYILRAQAINRRTGRPVEPESEFIIKIHDINDNEPIFTKEVYTATVP 169
Query: 273 EGALPGTSVMEVTATDADDDVNTYNAAIAYTILSQDPELPDKNMFTINRNTGVISVVTTG 332
E + GT V++VTATDADD +A + Y+IL P F++ TG+I
Sbjct: 170 EMSDVGTFVVQVTATDADDPTYGNSAKVVYSILQGQP------YFSVESETGIIKTALLN 223
Query: 333 LDRESFPTYTLVVQAADLQGE--GLSTTATAVITVTDTNDNPPIFNPTTYKGQVPENEA- 389
+DRE+ Y +V+QA D+ G+ GLS T T IT+TD NDNPP F +TY+ + PE+
Sbjct: 224 MDRENREQYQVVIQAKDMGGQMGGLSGTTTVNITLTDVNDNPPRFPQSTYQFKTPESSPP 283
Query: 390 NVVITTLKVTDADAPNTPAWEAVYTILNDDG-GQFVVTTNPVNNDGILKTAKGLDFEAKQ 448
I +K +DAD E Y+I + +G F V T+ +GI+ K LDFE K+
Sbjct: 284 GTPIGRIKASDADVGENA--EIEYSITDGEGLDMFDVITDQETQEGIITVKKLLDFEKKK 341
Query: 449 QYILHVAVTN--VVPFEVSLTT--STATVTVDVLDVNEAPIFVPPEKRVEVSEDFGVGQE 504
Y L V +N V P + L +ATV + V DV+E P+F +++ ED +
Sbjct: 342 VYTLKVEASNPYVEPRFLYLGPFKDSATVRIVVEDVDEPPVFSKLAYILQIREDAQINTT 401
Query: 505 ITSYTAQEPDTFMEQKITYRIWR--DTANWLEINPDTGAISTRAELDREDFEHVKNSTYT 562
I S TAQ+PD + Y + R D I+ G+I T LDRE +
Sbjct: 402 IGSVTAQDPDA-ARNPVKYSVDRHTDMDRIFNIDSGNGSIFTSKLLDRETL-----LWHN 455
Query: 563 ALIIATDNGSPVATGTGTLLLILSDVNDNAP-IPEPRTIFFCERNPKPQVI---NIIDAD 618
+IAT+ +P + L + + DVNDNAP E F CE+ Q+I + +D D
Sbjct: 456 ITVIATEINNPKQSSRVPLYIKVLDVNDNAPEFAEFYETFVCEKAKADQLIQTLHAVDKD 515
Query: 619 LPPNTSPFTAELTHGASA--NWTIQYNDPTQESIILKPK--MALEVGDYKINLKLMDN-- 672
P + F+ L A++ N+TIQ N I+ + E+ Y + + + DN
Sbjct: 516 DPYSGHQFSFSLAPEAASGSNFTIQDNKDNTAGILTRKNGYNRHEMSTYLLPVVISDNDY 575
Query: 673 --QNKDQVTTLEVSVCDCEGAAGVCRKAQPVE-AGLQIPAILGILGGILALLILILLLLL 729
Q+ T+ V CD G C + GL A++ IL I+ LL+ ++L
Sbjct: 576 PVQSSTGTVTVRVCACDHHGNMQSCHAEALIHPTGLSTGALVAILLCIVILLVTVVLFAA 635
Query: 730 FLRRRAVVKEPLLPPEDDTRDNVYYYDEEGGGEED-QDFDLSQLHRGLDARPEVTRNDVA 788
R+R KEPL+ ++D RDN+ Y++EGGGEED Q FD+ L R D+
Sbjct: 636 LRRQRK--KEPLIISKEDIRDNIVSYNDEGGGEEDTQAFDIGTLRNPEAIEDNKLRRDIV 693
Query: 789 PTLMSVPRYLPRPANPDEIGNFIDENLKAADTDPTAPPYDSLLVFDYEGSGSEAASLSSL 848
P + +PR P + ++ +FI++ LK DTDPTAPPYDSL + YEG+GS A SLSSL
Sbjct: 694 PEALFLPRRTPTARDNTDVRDFINQRLKENDTDPTAPPYDSLATYAYEGTGSVADSLSSL 753
Query: 849 NSSESDKDQDYDYLNEWGNRFKKLADMYGGGEDD 882
S +D DQDYDYL++WG RFKKLADMYGG + D
Sbjct: 754 ESVTTDADQDYDYLSDWGPRFKKLADMYGGVDSD 787
>gi|16306530 cadherin 10, type 2 preproprotein [Homo sapiens]
Length = 788
Score = 389 bits (999), Expect = e-108
Identities = 270/759 (35%), Positives = 399/759 (52%), Gaps = 47/759 (6%)
Query: 149 LRRQKRDWVIPPISCPENEKGPFPKNLVQIKSNKDK-EGKVFYSITGQGADTPPVGVFII 207
L RQKR W+ E G + + ++ S++DK +G + Y ++G GA T +FII
Sbjct: 49 LHRQKRGWMWNQFFLLEEYTGSDYQYVGKLHSDQDKGDGSLKYILSGDGAGT----LFII 104
Query: 208 ERETGWLKVTEPLDRERIATYTLFSHAVSSNG-NAVEDPMEILITVTDQNDNKPEFTQEV 266
+ +TG + T +DRE A YTL + A++ VE E +I + D NDN+P F +E+
Sbjct: 105 DEKTGDIHATRRIDREEKAFYTLRAQAINRRTLRPVEPESEFVIKIHDINDNEPTFPEEI 164
Query: 267 FKGSVMEGALPGTSVMEVTATDADDDVNTYNAAIAYTILSQDPELPDKNMFTINRNTGVI 326
+ SV E ++ GTSV++VTATDADD +A + Y+IL P F++ TG+I
Sbjct: 165 YTASVPEMSVVGTSVVQVTATDADDPSYGNSARVIYSILQGQP------YFSVEPETGII 218
Query: 327 SVVTTGLDRESFPTYTLVVQAADLQGE--GLSTTATAVITVTDTNDNPPIFNPTTYKGQV 384
++RE+ Y +V+QA D+ G+ GLS T T IT+TD NDNPP F T +V
Sbjct: 219 RTALPNMNRENREQYQVVIQAKDMGGQMGGLSGTTTVNITLTDVNDNPPRFPQNTIHLRV 278
Query: 385 PENE-ANVVITTLKVTDADAPNTPAWEAVYTILNDDG-GQFVVTTNPVNNDGILKTAKGL 442
E+ I ++K TDAD E Y I++ DG F + T +GI+ K L
Sbjct: 279 LESSPVGTAIGSVKATDADTGKNA--EVEYRIIDGDGTDMFDIVTEKDTQEGIITVKKPL 336
Query: 443 DFEAKQQYILHVAV--TNVVP--FEVSLTTSTATVTVDVLDVNEAPIFVPPEKRVEVSED 498
D+E+++ Y L V T+V P + + T V + + DV+E P+F EV ED
Sbjct: 337 DYESRRLYTLKVEAENTHVDPRFYYLGPFKDTTIVKISIEDVDEPPVFSRSSYLFEVHED 396
Query: 499 FGVGQEITSYTAQEPDTFMEQKITYRIWR--DTANWLEINPDTGAISTRAELDREDFEHV 556
VG I + A++PD+ + I + + R D I+ G++ T LDRE
Sbjct: 397 IEVGTIIGTVMARDPDS-ISSPIRFSLDRHTDLDRIFNIHSGNGSLYTSKPLDRE----- 450
Query: 557 KNSTYTALIIATDNGSPVATGTGTLLLILSDVNDNAP-IPEPRTIFFCERNPKP----QV 611
+ + +IA + +P T + + + DVNDNAP F CE N +P Q
Sbjct: 451 LSQWHNLTVIAAEINNPKETTRVAVFVRILDVNDNAPQFAVFYDTFVCE-NARPGQLIQT 509
Query: 612 INIIDADLPPNTSPFTAELTHGASANWTIQYNDPTQESIILKPK--MALEVGDYKINLKL 669
I+ +D D P F L + N+T+Q N+ I+ + E+ Y + + +
Sbjct: 510 ISAVDKDDPLGGQKFFFSLA-AVNPNFTVQDNEDNTARILTRKNGFNRHEISTYLLPVVI 568
Query: 670 MDN----QNKDQVTTLEVSVCDCEGAAGVCR-KAQPVEAGLQIPAILGILGGILALLILI 724
DN Q+ T+ V CD +G C +A + AGL A++ IL I+ LL+++
Sbjct: 569 SDNDYPIQSSTGTLTIRVCACDSQGNMQSCSAEALLLPAGLSTGALIAILLCIIILLVIV 628
Query: 725 LLLLLFLRRRAVVKEPLLPPEDDTRDNVYYYDEEGGGEED-QDFDLSQLHRGLDARPEVT 783
+L R+R KEPL+ ++D RDN+ Y++EGGGEED Q FD+ L +
Sbjct: 629 VLFAALKRQRK--KEPLILSKEDIRDNIVSYNDEGGGEEDTQAFDIGTLRNPAAIEEKKL 686
Query: 784 RNDVAPTLMSVPRYLPRPANPDEIGNFIDENLKAADTDPTAPPYDSLLVFDYEGSGSEAA 843
R D+ P + +PR P + ++ +FI+E LK D DPTAPPYDSL + YEG+ S A
Sbjct: 687 RRDIIPETLFIPRRTPTAPDNTDVRDFINERLKEHDLDPTAPPYDSLATYAYEGNDSIAE 746
Query: 844 SLSSLNSSESDKDQDYDYLNEWGNRFKKLADMYGGGEDD 882
SLSSL S ++ DQ+YDYL EWG RF KLA+MYGGGE D
Sbjct: 747 SLSSLESGTTEGDQNYDYLREWGPRFNKLAEMYGGGESD 785
>gi|4826702 desmocollin 1 isoform Dsc1b preproprotein [Homo sapiens]
Length = 840
Score = 380 bits (976), Expect = e-105
Identities = 261/777 (33%), Positives = 389/777 (50%), Gaps = 56/777 (7%)
Query: 3 PWSRSLSALLLLLQVSSWLCQEPEPCHPGFDAESYTFTVPRRHLERGRVLGRVNFEDCTG 62
P S LL L V + LC DA + HL+ ++G+VN E+C
Sbjct: 8 PGSIFCKQLLFSLLVLTLLC----------DACQKVYLRVPSHLQAETLVGKVNLEECL- 56
Query: 63 RQRTAYFSLDTRFKVGTDGVITVKRPLRFHNPQIHFLVYAWDSTYRKFST-KVTLNTVGH 121
+ + S D F++ DG I L + + F ++ D R+ KV L+ +
Sbjct: 57 KSASLIRSSDPAFRILEDGSIYTTHDLILSSERKSFSIFLSDGQRREQQEIKVVLSAREN 116
Query: 122 HHRPPPHQASVSGIQAELLTFPNSSPGLRRQKRDWVIPPISCPENEKGPFPKNLVQIKSN 181
H + L+R KR W P S EN GPFP+++ QI+S+
Sbjct: 117 KSPKKRHTKDTA---------------LKRSKRRWAPIPASLMENSLGPFPQHVQQIQSD 161
Query: 182 KDKEGKVFYSITGQGADTPPVGVFIIERETGWLKVTEPLDRERIATYTLFSHAVSSNGNA 241
+ +FYSI+G G D P +F IE++TG + T +DRE+ + L+ +A +++G A
Sbjct: 162 AAQNYTIFYSISGPGVDKEPFNLFYIEKDTGDIFCTRSIDREKYEQFALYGYATTADGYA 221
Query: 242 VEDPMEILITVTDQNDNKPEFTQEVFKGSVMEGALPGTSVMEVTATDADDDVNTYNAAIA 301
E P+ ++I + D NDN P F V +V E GTSV +VTATD D+ +T + +
Sbjct: 222 PEYPLPLIIKIEDDNDNAPYFEHRVTIFTVPENCRSGTSVGKVTATDLDEP-DTLHTRLK 280
Query: 302 YTILSQDPELPDKNMFTINRNTGVISVVTTGLDRESFPTYTLVVQAADLQGE--GLSTTA 359
Y IL Q P+ P F+I+ +TGVI+ T LDRE TY L+++ D+ G+ GL T
Sbjct: 281 YKILQQIPDHP--KHFSIHPDTGVITTTTPFLDREKCDTYQLIMEVRDMGGQPFGLFNTG 338
Query: 360 TAVITVTDTNDNPPIFNPTTYKGQVPENEANVVITTLKVTDADAPNTPAWEAVYTIL-ND 418
T I++ D NDNPP F T+Y +V EN +V I +KV D D PNTP +AVY IL +
Sbjct: 339 TITISLEDENDNPPSFTETSYVTEVEENRIDVEILRMKVQDQDLPNTPHSKAVYKILQGN 398
Query: 419 DGGQFVVTTNPVNNDGILKTAKGLDFEAKQQYILHVAVTNVVPFEVSL-----TTSTATV 473
+ G F+++T+P N+G+L K L++E +Q IL V V N F + T T TV
Sbjct: 399 ENGNFIISTDPNTNEGVLCVVKPLNYEVNRQVILQVGVINEAQFSKAASSQTPTMCTTTV 458
Query: 474 TVDVLDVNEAPIFVPPEKRVEVSEDFGVGQEITSYTAQEPDTFMEQKITYRIWRDTANWL 533
TV ++D +E P PP K ++ + F GQE+ Y A +P+ + + Y+ D NW
Sbjct: 459 TVKIIDSDEGPECHPPVKVIQSQDGFPAGQELLGYKALDPEISSGEGLRYQKLGDEDNWF 518
Query: 534 EINPDTGAISTRAELDREDFEHVKNSTYTALIIATDNGSPVATGTGTLLLILSDVNDNAP 593
EIN TG + T LDRE + VKN+ Y ++A D + + TGTL++ L D ND+AP
Sbjct: 519 EINQHTGDLRTLKVLDRES-KFVKNNQYNISVVAVD--AVGRSCTGTLVVHLDDYNDHAP 575
Query: 594 IPEPRTIFFCERNPKPQVINIIDADLPPNTSPFTAELTHGASANWTIQYNDPTQESIILK 653
+ + + C+ N V+ +D D P N PF L + AS NW I+ D ++ IL+
Sbjct: 576 QID-KEVTICQNNEDFAVLKPVDPDGPENGPPFQFFLDNSASKNWNIEEKD--GKTAILR 632
Query: 654 PKMALEVGDYKINLKLMDNQNKDQVTTLEVSVCDCEGAAGVCRKAQPVEAGLQIPAILG- 712
+ L+ Y + +++ D L V VCDC CR ++ ILG
Sbjct: 633 QRQNLDYNYYSVPIQIKDRHGLVATHMLTVRVCDC-STPSECRMKDKSTRDVRPNVILGR 691
Query: 713 ------ILGGILALLILILLLLLFLRRRAVVKEPLLPPEDDTRDNVYYYDEEGGGEE 763
+LG +L L IL + +R VK+ PED + N+ + EG GEE
Sbjct: 692 WAILAMVLGSVLLLCILFTCFCVTAKR--TVKKCF--PEDIAQQNLIVSNTEGPGEE 744
>gi|13435361 desmocollin 1 isoform Dsc1a preproprotein [Homo
sapiens]
Length = 894
Score = 380 bits (976), Expect = e-105
Identities = 261/777 (33%), Positives = 389/777 (50%), Gaps = 56/777 (7%)
Query: 3 PWSRSLSALLLLLQVSSWLCQEPEPCHPGFDAESYTFTVPRRHLERGRVLGRVNFEDCTG 62
P S LL L V + LC DA + HL+ ++G+VN E+C
Sbjct: 8 PGSIFCKQLLFSLLVLTLLC----------DACQKVYLRVPSHLQAETLVGKVNLEECL- 56
Query: 63 RQRTAYFSLDTRFKVGTDGVITVKRPLRFHNPQIHFLVYAWDSTYRKFST-KVTLNTVGH 121
+ + S D F++ DG I L + + F ++ D R+ KV L+ +
Sbjct: 57 KSASLIRSSDPAFRILEDGSIYTTHDLILSSERKSFSIFLSDGQRREQQEIKVVLSAREN 116
Query: 122 HHRPPPHQASVSGIQAELLTFPNSSPGLRRQKRDWVIPPISCPENEKGPFPKNLVQIKSN 181
H + L+R KR W P S EN GPFP+++ QI+S+
Sbjct: 117 KSPKKRHTKDTA---------------LKRSKRRWAPIPASLMENSLGPFPQHVQQIQSD 161
Query: 182 KDKEGKVFYSITGQGADTPPVGVFIIERETGWLKVTEPLDRERIATYTLFSHAVSSNGNA 241
+ +FYSI+G G D P +F IE++TG + T +DRE+ + L+ +A +++G A
Sbjct: 162 AAQNYTIFYSISGPGVDKEPFNLFYIEKDTGDIFCTRSIDREKYEQFALYGYATTADGYA 221
Query: 242 VEDPMEILITVTDQNDNKPEFTQEVFKGSVMEGALPGTSVMEVTATDADDDVNTYNAAIA 301
E P+ ++I + D NDN P F V +V E GTSV +VTATD D+ +T + +
Sbjct: 222 PEYPLPLIIKIEDDNDNAPYFEHRVTIFTVPENCRSGTSVGKVTATDLDEP-DTLHTRLK 280
Query: 302 YTILSQDPELPDKNMFTINRNTGVISVVTTGLDRESFPTYTLVVQAADLQGE--GLSTTA 359
Y IL Q P+ P F+I+ +TGVI+ T LDRE TY L+++ D+ G+ GL T
Sbjct: 281 YKILQQIPDHP--KHFSIHPDTGVITTTTPFLDREKCDTYQLIMEVRDMGGQPFGLFNTG 338
Query: 360 TAVITVTDTNDNPPIFNPTTYKGQVPENEANVVITTLKVTDADAPNTPAWEAVYTIL-ND 418
T I++ D NDNPP F T+Y +V EN +V I +KV D D PNTP +AVY IL +
Sbjct: 339 TITISLEDENDNPPSFTETSYVTEVEENRIDVEILRMKVQDQDLPNTPHSKAVYKILQGN 398
Query: 419 DGGQFVVTTNPVNNDGILKTAKGLDFEAKQQYILHVAVTNVVPFEVSL-----TTSTATV 473
+ G F+++T+P N+G+L K L++E +Q IL V V N F + T T TV
Sbjct: 399 ENGNFIISTDPNTNEGVLCVVKPLNYEVNRQVILQVGVINEAQFSKAASSQTPTMCTTTV 458
Query: 474 TVDVLDVNEAPIFVPPEKRVEVSEDFGVGQEITSYTAQEPDTFMEQKITYRIWRDTANWL 533
TV ++D +E P PP K ++ + F GQE+ Y A +P+ + + Y+ D NW
Sbjct: 459 TVKIIDSDEGPECHPPVKVIQSQDGFPAGQELLGYKALDPEISSGEGLRYQKLGDEDNWF 518
Query: 534 EINPDTGAISTRAELDREDFEHVKNSTYTALIIATDNGSPVATGTGTLLLILSDVNDNAP 593
EIN TG + T LDRE + VKN+ Y ++A D + + TGTL++ L D ND+AP
Sbjct: 519 EINQHTGDLRTLKVLDRES-KFVKNNQYNISVVAVD--AVGRSCTGTLVVHLDDYNDHAP 575
Query: 594 IPEPRTIFFCERNPKPQVINIIDADLPPNTSPFTAELTHGASANWTIQYNDPTQESIILK 653
+ + + C+ N V+ +D D P N PF L + AS NW I+ D ++ IL+
Sbjct: 576 QID-KEVTICQNNEDFAVLKPVDPDGPENGPPFQFFLDNSASKNWNIEEKD--GKTAILR 632
Query: 654 PKMALEVGDYKINLKLMDNQNKDQVTTLEVSVCDCEGAAGVCRKAQPVEAGLQIPAILG- 712
+ L+ Y + +++ D L V VCDC CR ++ ILG
Sbjct: 633 QRQNLDYNYYSVPIQIKDRHGLVATHMLTVRVCDC-STPSECRMKDKSTRDVRPNVILGR 691
Query: 713 ------ILGGILALLILILLLLLFLRRRAVVKEPLLPPEDDTRDNVYYYDEEGGGEE 763
+LG +L L IL + +R VK+ PED + N+ + EG GEE
Sbjct: 692 WAILAMVLGSVLLLCILFTCFCVTAKR--TVKKCF--PEDIAQQNLIVSNTEGPGEE 744
>gi|16306539 cadherin 8, type 2 preproprotein [Homo sapiens]
Length = 799
Score = 376 bits (965), Expect = e-104
Identities = 279/788 (35%), Positives = 393/788 (49%), Gaps = 61/788 (7%)
Query: 129 QASVSGIQAELLTFPNSSPGLRRQKRDWVIPPISCPENEKGPFPKNLVQIKSNKDKEGK- 187
Q +SG EL + L R KR WV + E GP P + ++ ++ D K
Sbjct: 36 QVLMSGSPLELNSLGEEQRILNRSKRGWVWNQMFVLEEFSGPEPILVGRLHTDLDPGSKK 95
Query: 188 VFYSITGQGADTPPVGVFIIERETGWLKVTEPLDRERIATYTLFSHAVS-SNGNAVEDPM 246
+ Y ++G GA T +F I TG + + LDRE A YTL + AV +E P
Sbjct: 96 IKYILSGDGAGT----IFQINDVTGDIHAIKRLDREEKAEYTLTAQAVDWETSKPLEPPS 151
Query: 247 EILITVTDQNDNKPEFTQEVFKGSVMEGALPGTSVMEVTATDADDDVNTYNAAIAYTILS 306
E +I V D NDN PEF + +V E ++ GTSV VTATDADD V +A + Y+IL
Sbjct: 152 EFIIKVQDINDNAPEFLNGPYHATVPEMSILGTSVTNVTATDADDPVYGNSAKLVYSILE 211
Query: 307 QDPELPDKNMFTINRNTGVISVVTTGLDRESFPTYTLVVQAADLQGE--GLSTTATAVIT 364
P F+I T +I +DRE+ Y +V+QA D+ G GLS T T +T
Sbjct: 212 GQP------YFSIEPETAIIKTALPNMDREAKEEYLVVIQAKDMGGHSGGLSGTTTLTVT 265
Query: 365 VTDTNDNPPIFNPTTYKGQVPENEA-NVVITTLKVTDADAPNTPAWEAVYTILNDDG-GQ 422
+TD NDNPP F + Y VPE+ I +K D D ++ Y I++ DG
Sbjct: 266 LTDVNDNPPKFAQSLYHFSVPEDVVLGTAIGRVKANDQDIGENA--QSSYDIIDGDGTAL 323
Query: 423 FVVTTNPVNNDGILKTAKGLDFEAKQQYILHVAVTNVV---------PFEVSLTTSTATV 473
F +T++ DGI++ K LDFE K+ Y L V NV PF+ TATV
Sbjct: 324 FEITSDAQAQDGIIRLRKPLDFETKKSYTLKVEAANVHIDPRFSGRGPFK-----DTATV 378
Query: 474 TVDVLDVNEAPIFVPPEKRVEVSEDFGVGQEITSYTAQEPDTFMEQKITYRIWR--DTAN 531
+ V D +E P+F P +EV E+ + I TA++PD I + I R D
Sbjct: 379 KIVVEDADEPPVFSSPTYLLEVHENAALNSVIGQVTARDPD-ITSSPIRFSIDRHTDLER 437
Query: 532 WLEINPDTGAISTRAELDREDFEHVKNSTYTALIIATDNGSPVATGTGTLLLILSDVNDN 591
IN D G I+ LDRE + + IIAT+ + + + + DVNDN
Sbjct: 438 QFNINADDGKITLATPLDRE-----LSVWHNITIIATEIRNHSQISRVPVAIKVLDVNDN 492
Query: 592 AP-IPEPRTIFFCERNPKP----QVINIIDADLPPNTSPFTAELTHGA--SANWTIQYND 644
AP F CE N KP Q ++ +D D P N F L + N+TI+ N+
Sbjct: 493 APEFASEYEAFLCE-NGKPGQVIQTVSAMDKDDPKNGHYFLYSLLPEMVNNPNFTIKKNE 551
Query: 645 PTQESIILKP----KMALEVGDYKINLKLMDNQNKDQVTTLEVSVCDC--EGAAGVCR-K 697
SI+ K + EV I + N +TL + VC C +G C +
Sbjct: 552 DNSLSILAKHNGFNRQKQEVYLLPIIISDSGNPPLSSTSTLTIRVCGCSNDGVVQSCNVE 611
Query: 698 AQPVEAGLQIPAILGILGGILALLILILLLLLFLRRRAVVKEPLLPPED-DTRDNVYYYD 756
A + GL + A++ IL I+ LL++++L + R + EPL+ +D D R+N+ YD
Sbjct: 612 AYVLPIGLSMGALIAILACIILLLVIVVLFVTLRRHK---NEPLIIKDDEDVRENIIRYD 668
Query: 757 EEGGGEEDQD-FDLSQLHRGLDARPEVTRNDVAPTLMSVPRYLPRPA-NPDEIGNFIDEN 814
+EGGGEED + FD++ L + R D+ P L +PR P N ++ FI+
Sbjct: 669 DEGGGEEDTEAFDIATLQNPDGINGFLPRKDIKPDLQFMPRQGLAPVPNGVDVDEFINVR 728
Query: 815 LKAADTDPTAPPYDSLLVFDYEGSGSEAASLSSLNSSESDKDQDYDYLNEWGNRFKKLAD 874
L AD DPTAPPYDS+ ++ YEG GS A SLSSL S+ SD DQ++DYL++WG RFK+L +
Sbjct: 729 LHEADNDPTAPPYDSIQIYGYEGRGSVAGSLSSLESTTSDSDQNFDYLSDWGPRFKRLGE 788
Query: 875 MYGGGEDD 882
+Y GE D
Sbjct: 789 LYSVGESD 796
>gi|16306532 cadherin 11, type 2 preproprotein [Homo sapiens]
Length = 796
Score = 374 bits (961), Expect = e-103
Identities = 277/795 (34%), Positives = 402/795 (50%), Gaps = 76/795 (9%)
Query: 122 HHRPPPHQASVSGIQAELLTFPNSSPGLRRQKRDWVIPPISCPENEKGPFPKNLVQIKSN 181
H RP H G + ++L +R KR WV E GP P + ++ S+
Sbjct: 30 HLRPSFHGHHEKGKEGQVL---------QRSKRGWVWNQFFVIEEYTGPDPVLVGRLHSD 80
Query: 182 KDK-EGKVFYSITGQGADTPPVGVFIIERETGWLKVTEPLDRERIATYTLFSHAVSSNGN 240
D +G + Y ++G+GA T +F+I+ ++G + T+ LDRE A YTL + AV + N
Sbjct: 81 IDSGDGNIKYILSGEGAGT----IFVIDDKSGNIHATKTLDREERAQYTLMAQAVDRDTN 136
Query: 241 A-VEDPMEILITVTDQNDNKPEFTQEVFKGSVMEGALPGTSVMEVTATDADDDVNTYNAA 299
+E P E ++ V D NDN PEF E + +V E + GTSV++VTA+DADD +A
Sbjct: 137 RPLEPPSEFIVKVQDINDNPPEFLHETYHANVPERSNVGTSVIQVTASDADDPTYGNSAK 196
Query: 300 IAYTILSQDPELPDKNMFTINRNTGVISVVTTGLDRESFPTYTLVVQAADLQGE--GLST 357
+ Y+IL P F++ TG+I +DRE+ Y +V+QA D+ G GLS
Sbjct: 197 LVYSILEGQP------YFSVEAQTGIIRTALPNMDREAKEEYHVVIQAKDMGGHMGGLSG 250
Query: 358 TATAVITVTDTNDNPPIFNPTTYKGQVPENEA-NVVITTLKVTDADAPNTPAWEAVYTIL 416
T IT+TD NDNPP F + Y+ V E + +K D D Y I+
Sbjct: 251 TTKVTITLTDVNDNPPKFPQSVYQMSVSEAAVPGEEVGRVKAKDPDIGENGL--VTYNIV 308
Query: 417 NDDGGQ-FVVTTNPVNNDGILKTAKGLDFEAKQQYILHVAVTNVV---------PFEVSL 466
+ DG + F +TT+ +G++K K +DFE K+ Y L V NV PF+
Sbjct: 309 DGDGMESFEITTDYETQEGVIKLKKPVDFETKRAYSLKVEAANVHIDPKFISNGPFK--- 365
Query: 467 TTSTATVTVDVLDVNEAPIFVPPEKRVEVSEDFGVGQEITSYTAQEPDTFMEQKITYRIW 526
T TV + V D +E P+F+ P EV E+ G + A++PD I Y I
Sbjct: 366 --DTVTVKISVEDADEPPMFLAPSYIHEVQENAAAGTVVGRVHAKDPDA-ANSPIRYSID 422
Query: 527 R--DTANWLEINPDTGAISTRAELDREDFEHVKNSTYTALIIATDNGSPVATGTGTLLLI 584
R D + INP+ G I T LDRE+ + + + A I + V L
Sbjct: 423 RHTDLDRFFTINPEDGFIKTTKPLDREETAWLNITVFAAEIHNRHQEAKVPVAIRVL--- 479
Query: 585 LSDVNDNAP-IPEPRTIFFCERNP-KP---QVINIIDADLPPNTS-------PFTAELTH 632
DVNDNAP P F CE + KP Q I I AD +T+ E+ H
Sbjct: 480 --DVNDNAPKFAAPYEGFICESDQTKPLSNQPIVTISADDKDDTANGPRFIFSLPPEIIH 537
Query: 633 GASANWTIQYN-DPTQESIILKPKMALEVGD-YKINLKLMDN----QNKDQVTTLEVSVC 686
+ N+T++ N D T + + + D Y + + + D + T++V C
Sbjct: 538 --NPNFTVRDNRDNTAGVYARRGGFSRQKQDLYLLPIVISDGGIPPMSSTNTLTIKVCGC 595
Query: 687 DCEGAAGVCR-KAQPVEAGLQIPAILGILGGILALLILILLLLLFLRRRAVVKEPLLP-P 744
D GA C +A + AGL A++ IL I+ LL++++L + R++ KEPL+
Sbjct: 596 DVNGALLSCNAEAYILNAGLSTGALIAILACIVILLVIVVLFVTLRRQK---KEPLIVFE 652
Query: 745 EDDTRDNVYYYDEEGGGEEDQD-FDLSQLHRGLDARPEVTRNDVAPTLMSVPRYLPRPA- 802
E+D R+N+ YD+EGGGEED + FD++ L + R D+ P +PR RPA
Sbjct: 653 EEDVRENIITYDDEGGGEEDTEAFDIATLQNPDGINGFIPRKDIKPEYQYMPRPGLRPAP 712
Query: 803 NPDEIGNFIDENLKAADTDPTAPPYDSLLVFDYEGSGSEAASLSSLNSSESDKDQDYDYL 862
N ++ +FI+ ++ AD DPTAPPYDS+ ++ YEG GS A SLSSL S+ +D D DYDYL
Sbjct: 713 NSVDVDDFINTRIQEADNDPTAPPYDSIQIYGYEGRGSVAGSLSSLESATTDSDLDYDYL 772
Query: 863 NEWGNRFKKLADMYG 877
WG RFKKLAD+YG
Sbjct: 773 QNWGPRFKKLADLYG 787
>gi|4826671 cadherin 18, type 2 preproprotein [Homo sapiens]
Length = 790
Score = 373 bits (958), Expect = e-103
Identities = 271/783 (34%), Positives = 406/783 (51%), Gaps = 50/783 (6%)
Query: 128 HQASVSGIQAELLTFPNSSPGLRRQKRDWVIPPISCPENEKGPFPKNLVQIKSNKDK-EG 186
H +S+ ++ + + R KR WV E GP P+ + ++ SN DK +G
Sbjct: 27 HHSSIKVMRNQTKHIEGETEVHHRPKRGWVWNQFFVLEEHMGPDPQYVGKLHSNSDKGDG 86
Query: 187 KVFYSITGQGADTPPVGVFIIERETGWLKVTEPLDRERIATYTLFSHAVSSNGNAVEDP- 245
V Y +TG+GA T +FII+ TG + T+ LDRE+ Y L + A+ N +P
Sbjct: 87 SVKYILTGEGAGT----IFIIDDTTGDIHSTKSLDREQKTHYVLHAQAIDRRTNKPLEPE 142
Query: 246 MEILITVTDQNDNKPEFTQEVFKGSVMEGALPGTSVMEVTATDADDDVNTYNAAIAYTIL 305
E +I V D NDN P+FT + +V E + GTSV++VTATDADD +A + Y+IL
Sbjct: 143 SEFIIKVQDINDNAPKFTDGPYIVTVPEMSDMGTSVLQVTATDADDPTYGNSARVVYSIL 202
Query: 306 SQDPELPDKNMFTINRNTGVISVVTTGLDRESFPTYTLVVQAADLQGE--GLSTTATAVI 363
P F+++ TGVI +DRE+ Y++V+QA D+ G+ GLS + T I
Sbjct: 203 QGQP------YFSVDPKTGVIRTALHNMDREAREHYSVVIQAKDMAGQVGGLSGSTTVNI 256
Query: 364 TVTDTNDNPPIFNPTTYKGQVPEN-EANVVITTLKVTDADAPNTPAWEAVYTILNDDG-G 421
T+TD NDNPP F Y+ VPE+ + + +K DAD + + Y+I+N DG G
Sbjct: 257 TLTDVNDNPPRFPQKHYQLYVPESAQVGSAVGKIKANDADTGSNA--DMTYSIINGDGMG 314
Query: 422 QFVVTTNPVNNDGILKTAKGLDFEAKQQYILHVAVTNV-VPFEVSLTTSTATVT---VDV 477
F ++T+ +GIL K L++E K+ Y L++ N + F S T + V
Sbjct: 315 IFSISTDKETREGILSLKKPLNYEKKKSYTLNIEGANTHLDFRFSHLGPFKDATMLKIIV 374
Query: 478 LDVNEAPIFVPPEKRVEVSEDFGVGQEITSYTAQEPDT---FMEQKITYRIWRDTANWLE 534
DV+E P+F P +EV E+ +G + + AQ+PD+ + I Y + D +
Sbjct: 375 GDVDEPPLFSMPSYLMEVYENAKIGTVVGTVLAQDPDSTNSLVRYFINYNVEDD--RFFN 432
Query: 535 INPDTGAISTRAELDREDFEHVKNSTYTALIIATDNGSPVATGTGTLLLILSDVNDNAP- 593
I+ +TG I T LDRE+ Y + A++ +P T+ + + DVNDN P
Sbjct: 433 IDANTGTIRTTKVLDREE-----TPWYNITVTASEIDNPDLLSHVTVGIRVLDVNDNPPE 487
Query: 594 IPEPRTIFFCERNPKPQVINII---DADLPPNTSPFTAELTHG--ASANWTIQYNDPTQE 648
+ I CE + QVI+ I D D N F L + N+T++ N+
Sbjct: 488 LAREYDIIVCENSKPGQVIHTISATDKDDFANGPRFNFFLDERLPVNPNFTLKDNEDNTA 547
Query: 649 SIILKPK-MALEVGD-YKINLKLMDN--QNKDQVTTLEVSVCDCE--GAAGVCR-KAQPV 701
SI+ + + + V D Y + + + D + +TL + VC CE G C +A
Sbjct: 548 SILTRRRRFSRTVQDVYYLPIMISDGGIPSLSSSSTLTIRVCACERDGRVRTCHAEAFLS 607
Query: 702 EAGLQIPAILGILGGILALLILILLLLLFLRRRAVVKEPLLPPEDDTRDNVYYYDEEGGG 761
AGL A++ IL L +LIL+ +++LF+ R KEPL+ E+D R+NV YD+EGGG
Sbjct: 608 SAGLSTGALIAIL---LCVLILLAIVVLFITLRRSKKEPLIISEEDVRENVVTYDDEGGG 664
Query: 762 EEDQD-FDLSQLHRGLDARPEVTRNDVAPTLMSVPRYLPRPANPD-EIGNFIDENLKAAD 819
EED + FD++ L A R D+ P + PR+ ++ FI + L AD
Sbjct: 665 EEDTEAFDITALRNPSAAEELKYRRDIRPEVKLTPRHQTSSTLESIDVQEFIKQRLAEAD 724
Query: 820 TDPTAPPYDSLLVFDYEGSGSEAASLSSLNSSESDKDQDYDYLNEWGNRFKKLADMYGGG 879
DP+ PPYDSL + YEG SEA S+SSL+S+ + DQDY YL +WG FKKLA++YG
Sbjct: 725 LDPSVPPYDSLQTYAYEGQRSEAGSISSLDSATTQSDQDYHYLGDWGPEFKKLAELYGEI 784
Query: 880 EDD 882
E +
Sbjct: 785 ESE 787
>gi|90193626 cadherin 9, type 2 preproprotein [Homo sapiens]
Length = 789
Score = 371 bits (953), Expect = e-102
Identities = 267/762 (35%), Positives = 391/762 (51%), Gaps = 50/762 (6%)
Query: 149 LRRQKRDWVIPPISCPENEKGPFPKNLVQIKSNKDK-EGKVFYSITGQGADTPPVGVFII 207
LRR KR W+ E G + + ++ +++DK +G + Y +TG GA + +F+I
Sbjct: 48 LRRTKRGWMWNQFFLLEEYTGTDTQYVGKLHTDQDKGDGNLKYILTGDGAGS----LFVI 103
Query: 208 ERETGWLKVTEPLDRERIATYTLFSHAVS-SNGNAVEDPMEILITVTDQNDNKPEFTQEV 266
+ TG + + LDRE + Y L + A+ G VE E +I + D NDN+P+FT+++
Sbjct: 104 DENTGDIHAAKKLDREEKSLYILRAKAIDRKTGRQVEPESEFIIKIHDINDNEPKFTKDL 163
Query: 267 FKGSVMEGALPGTSVMEVTATDADDDVNTYNAAIAYTILSQDPELPDKNMFTINRNTGVI 326
+ SV E + GTSV++VTATDADD +A + Y+IL P F+++ +G+I
Sbjct: 164 YTASVPEMSGVGTSVIQVTATDADDANYGNSAKVVYSILQGQP------YFSVDPESGII 217
Query: 327 SVVTTGLDRESFPTYTLVVQAADLQGE--GLSTTATAVITVTDTNDNPPIFNPTTYKGQV 384
+ RE+ Y +V+QA D+ G+ GLS T T IT+TD N+NPP F +TY+
Sbjct: 218 KTALPDMSRENREQYQVVIQAKDMGGQMGGLSGTTTVNITLTDVNNNPPRFPQSTYQFNS 277
Query: 385 PEN-EANVVITTLKVTDADAPNTPAWEAVYTILNDDGGQ-FVVTTNPVNNDGILKTAKGL 442
PE+ + +K D D E Y+I DG F V T+ +GI+ + L
Sbjct: 278 PESVPLGTHLGRIKANDPDVGENAEME--YSIAEGDGADMFDVITDKDTQEGIITVKQNL 335
Query: 443 DFEAKQQYILHVAVTNVVP----FEVSLTTSTATVTVDVLDVNEAPIFVPPEKRVEVSED 498
DFE + Y L V +N P + TA V + V D++E P+F +EV ED
Sbjct: 336 DFENQMLYTLRVDASNTHPDPRFLHLGPFKDTAVVKISVEDIDEPPVFTKVSYLIEVDED 395
Query: 499 FGVGQEITSYTAQEPDTFMEQKITYRIWR--DTANWLEINPDTGAISTRAELDREDFEHV 556
G I TA +PD I Y + R D I+ + G+I T LDRE
Sbjct: 396 VKEGSIIGQVTAYDPDA-RNNLIKYSVDRHTDMDRIFGIHSENGSIFTLKALDRES---- 450
Query: 557 KNSTYTALIIATDNGSPVATGTGTLLLILSDVNDNAP-IPEPRTIFFCERNPKP----QV 611
+ + + AT+ +P + + + + D+ND+AP F CE N KP Q
Sbjct: 451 -SPWHNITVTATEINNPKQSSHIPVFIRILDINDHAPEFAMYYETFVCE-NAKPGQLIQT 508
Query: 612 INIIDADLPPNTSPFTAELT--HGASANWTIQYNDPTQESIILKPK--MALEVGDYKINL 667
++++D D PP F E + N+TI N I+ + ++ Y + +
Sbjct: 509 VSVMDKDDPPRGHKFFFEPVPEFTLNPNFTIVDNKDNTAGIMTRKDGYSRNKMSTYLLPI 568
Query: 668 KLMDN----QNKDQVTTLEVSVCDCEGAAGVCR-KAQPVEAGLQIPAILGILGGILALLI 722
+ DN Q+ T+ V CD +G C +A + AGL A++ IL +L LLI
Sbjct: 569 LIFDNDYPIQSSTGTLTIRVCACDNQGNMQSCTAEALILSAGLSTGALVAILLCVLILLI 628
Query: 723 LILLLLLFLRRRAVVKEPLLPPEDDTRDNVYYYDEEGGGEED-QDFDLSQLHRGLDARPE 781
L++L R+R KEPL+ +DD RDN+ Y++EGGGEED Q FD+ L
Sbjct: 629 LVVLFAALKRQRK--KEPLIISKDDVRDNIVTYNDEGGGEEDTQAFDIGTLRNPEAREDS 686
Query: 782 VTRNDVAP-TLMSVPRYLPRPANPDEIGNFIDENLKAADTDPTAPPYDSLLVFDYEGSGS 840
R DV P T+ + R +P N D + +FI LK D DP+APPYDSL + YEG+ S
Sbjct: 687 KLRRDVMPETIFQIRRTVPLWENID-VQDFIHRRLKENDADPSAPPYDSLATYAYEGNDS 745
Query: 841 EAASLSSLNSSESDKDQDYDYLNEWGNRFKKLADMYGGGEDD 882
A SLSSL S +D +QDYDYL++WG RFKKLADMYGG + D
Sbjct: 746 IADSLSSLESLTADCNQDYDYLSDWGPRFKKLADMYGGDDSD 787
>gi|16445393 cadherin 12, type 2 preproprotein [Homo sapiens]
Length = 794
Score = 370 bits (951), Expect = e-102
Identities = 274/798 (34%), Positives = 400/798 (50%), Gaps = 76/798 (9%)
Query: 124 RPPPHQASVSGIQAELLTFPNSSPGLRRQKRDWVIPPISCPENEKGPFPKNLVQIKSNKD 183
+P P Q + + ++ P +R KR WV E G P+ + ++ S+ D
Sbjct: 24 QPQPQQTLATEPRENVIHLPGQRSHFQRVKRGWVWNQFFVLEEYVGSEPQYVGKLHSDLD 83
Query: 184 K-EGKVFYSITGQGADTPPVGVFIIERETGWLKVTEPLDRERIATYTLFSHAVS-SNGNA 241
K EG V Y+++G GA T VF I+ TG + LDRE YTL + AV
Sbjct: 84 KGEGTVKYTLSGDGAGT----VFTIDETTGDIHAIRSLDREEKPFYTLRAQAVDIETRKP 139
Query: 242 VEDPMEILITVTDQNDNKPEFTQEVFKGSVMEGALPGTSVMEVTATDADDDVNTYNAAIA 301
+E E +I V D NDN+P+F + +V E + G V++V ATDADD +A +
Sbjct: 140 LEPESEFIIKVQDINDNEPKFLDGPYVATVPEMSPVGAYVLQVKATDADDPTYGNSARVV 199
Query: 302 YTILSQDPELPDKNMFTINRNTGVISVVTTGLDRESFPTYTLVVQAADLQGE--GLSTTA 359
Y+IL P F+I+ TGVI +DRE Y +++QA D+ G+ GL+ T
Sbjct: 200 YSILQGQP------YFSIDPKTGVIRTALPNMDREVKEQYQVLIQAKDMGGQLGGLAGTT 253
Query: 360 TAVITVTDTNDNPPIFNPTTYKGQVPENEA-NVVITTLKVTDADAPNTPAWEAVYTILND 418
IT+TD NDNPP F + + +VPE+ I ++ D D E Y I+
Sbjct: 254 IVNITLTDVNDNPPRFPKSIFHLKVPESSPIGSAIGRIRAVDPDFGQNA--EIEYNIVPG 311
Query: 419 DGGQ-FVVTTNPVNNDGILKTAKGLDFEAKQQYILHVAVTNVV---------PFEVSLTT 468
DGG F + T+ +G++K K LDFE K+ Y V +N+ PF+
Sbjct: 312 DGGNLFDIVTDEDTQEGVIKLKKPLDFETKKAYTFKVEASNLHLDHRFHSAGPFK----- 366
Query: 469 STATVTVDVLDVNEAPIFVPPEKRVEVSEDFGVGQEITSYTAQEPDTFMEQKITYRIWR- 527
TATV + VLDV+E P+F P +EV ED VG I + TAQ+ D + W+
Sbjct: 367 DTATVKISVLDVDEPPVFSKPLYTMEVYEDTPVGTIIGAVTAQDLDVGSSAVRYFIDWKS 426
Query: 528 DTANWLEINPDTGAISTRAELDREDFEHVKNSTYTALIIATDNGSPVATGTGTLLLILSD 587
D ++ I+ + G I+T LDRE + Y IIA+ +P+ T +L+ + D
Sbjct: 427 DGDSYFTIDGNEGTIATNELLDRES-----TAQYNFSIIASKVSNPLLTSKVNILINVLD 481
Query: 588 VNDNAP-IPEPRTIFFCERNPKP----QVINIIDADLPPNTSPFTAELTHGASA--NWTI 640
VN+ P I P CE N KP Q+++ D DL P F+ L+ A+ N+T+
Sbjct: 482 VNEFPPEISVPYETAVCE-NAKPGQIIQIVSAADRDLSPAGQQFSFRLSPEAAIKPNFTV 540
Query: 641 Q---------------YNDPTQESIILKPKMALEVGDYKINLKLMDNQNKDQVTTLEVSV 685
+ Y+ QE L + +E Y + Q+ T+ V
Sbjct: 541 RDFRNNTAGIETRRNGYSRRQQELYFLP--VVIEDSSYPV-------QSSTNTMTIRVCR 591
Query: 686 CDCEGAAGVCR-KAQPVEAGLQIPAILGILGGILALLILILLLLLFLR-RRAVVKEPLLP 743
CD +G C +A + GL A++ IL L ++IL+ +++L++ RR K+ L+
Sbjct: 592 CDSDGTILSCNVEAIFLPVGLSTGALIAIL---LCIVILLAIVVLYVALRRQKKKDTLMT 648
Query: 744 PEDDTRDNVYYYDEEGGGEED-QDFDLSQLHRGLDARPEVTRNDVAPTLMSVPRYLPRPA 802
++D RDNV +YD+EGGGEED Q FD+ L R D+ P + +PR P
Sbjct: 649 SKEDIRDNVIHYDDEGGGEEDTQAFDIGALRNPKVIEENKIRRDIKPDSLCLPRQRPPME 708
Query: 803 NPDEIGNFIDENLKAADTDPTAPPYDSLLVFDYEGSGSEAASLSSLNSSESDKDQDYDYL 862
+ +I +FI + L+ D DPTAPPYDSL + YEGSGS A SLSS++S ++ DQDYDYL
Sbjct: 709 DNTDIRDFIHQRLQENDVDPTAPPYDSLATYAYEGSGSVAESLSSIDSLTTEADQDYDYL 768
Query: 863 NEWGNRFKKLADMYGGGE 880
+WG RFK LADM+G E
Sbjct: 769 TDWGPRFKVLADMFGEEE 786
>gi|13435366 desmocollin 2 isoform Dsc2b preproprotein [Homo
sapiens]
Length = 847
Score = 355 bits (911), Expect = 1e-97
Identities = 247/776 (31%), Positives = 381/776 (49%), Gaps = 49/776 (6%)
Query: 2 GPWSRSLSALLLLLQVSSWLCQEPEPCHPGFDAESYTFTVPRRHLERGRVLGRVNFEDCT 61
G W+ +L LLLL + L + C ++ T VP + L+ +++GRVN ++C
Sbjct: 8 GSWNGALCRLLLL--TLAILIFASDAC------KNVTLHVPSK-LDAEKLVGRVNLKECF 58
Query: 62 GRQRTAYFSLDTRFKVGTDGVITVKRPLRFHNPQIHFLVYAWDSTYRKFSTKVTLNTVGH 121
+ S D F++ DG + + + + F + +T + K+ +
Sbjct: 59 TAANLIHSS-DPDFQILEDGSVYTTNTILLSSEKRSFTILL-SNTENQEKKKIFVFL--- 113
Query: 122 HHRPPPHQASVSGIQAELLTFPNSSPGLRRQKRDWVIPPISCPENEKGPFPKNLVQIKSN 181
HQ V L LRR KR W P S EN GPFP L Q++S+
Sbjct: 114 -----EHQTKV------LKKRHTKEKVLRRAKRRWAPIPCSMLENSLGPFPLFLQQVQSD 162
Query: 182 KDKEGKVFYSITGQGADTPPVGVFIIERETGWLKVTEPLDRERIATYTLFSHAVSSNGNA 241
+ ++YSI G G D P +F +ER+TG L T P+DRE+ ++ + + A + +G
Sbjct: 163 TAQNYTIYYSIRGPGVDQEPRNLFYVERDTGNLYCTRPVDREQYESFEIIAFATTPDGYT 222
Query: 242 VEDPMEILITVTDQNDNKPEFTQEVFKGSVMEGALPGTSVMEVTATDADDDVNTYNAAIA 301
E P+ ++I + D+NDN P FT+E + ++ E GT+V +V ATD D+ +T + +
Sbjct: 223 PELPLPLIIKIEDENDNYPIFTEETYTFTIFENCRVGTTVGQVCATDKDEP-DTMHTRLK 281
Query: 302 YTILSQDPELPDKNMFTINRNTGVISVVTTGLDRESFPTYTLVVQAADLQGE--GLSTTA 359
Y+I+ Q P P +F+++ TGVI+ ++ LDRE Y L ++ D+ G+ GL TT+
Sbjct: 282 YSIIGQVP--PSPTLFSMHPTTGVITTTSSQLDRELIDKYQLKIKVQDMDGQYFGLQTTS 339
Query: 360 TAVITVTDTNDNPPIFNPTTYKGQVPENEANVVITTLKVTDADAPNTPAWEAVYTIL-ND 418
T +I + D ND+ P F T+Y V EN +V I + V D D NT W A YTIL +
Sbjct: 340 TCIINIDDVNDHLPTFTRTSYVTSVEENTVDVEILRVTVEDKDLVNTANWRANYTILKGN 399
Query: 419 DGGQFVVTTNPVNNDGILKTAKGLDFEAKQQYILHVAVTNVVPFEVSLT----TSTATVT 474
+ G F + T+ N+G+L K L++E KQQ IL + V N PF + STATVT
Sbjct: 400 ENGNFKIVTDAKTNEGVLCVVKPLNYEEKQQMILQIGVVNEAPFSREASPRSAMSTATVT 459
Query: 475 VDVLDVNEAPIFVPPEKRVEVSEDFGVGQEITSYTAQEPDTFMEQKITYRIWRDTANWLE 534
V+V D +E P PP + V + E+ VG Y A +P+T I Y+ D W+
Sbjct: 460 VNVEDQDEGPECNPPIQTVRMKENAEVGTTSNGYKAYDPETRSSSGIRYKKLTDPTGWVT 519
Query: 535 INPDTGAISTRAELDREDFEHVKNSTYTALIIATDNGSPVATGTGTLLLILSDVNDNAPI 594
I+ +TG+I LDRE E +KN Y ++A+D G T TGTL +IL DVNDN+P
Sbjct: 520 IDENTGSIKVFRSLDRE-AETIKNGIYNITVLASDQGG--RTCTGTLGIILQDVNDNSPF 576
Query: 595 PEPRTIFFCERNPKPQVINIIDADLPPNTSPFTAEL---THGASANWTIQYNDPTQESII 651
+T+ C+ I +D D P + PF L T W ++ + T +
Sbjct: 577 IPKKTVIICKPTMSSAEIVAVDPDEPIHGPPFDFSLESSTSEVQRMWRLKAINDTAARLS 636
Query: 652 LKPKMALEVGDYKINLKLMDNQNKDQVTTLEVSVCDCEGAAGVCRKAQPVEAGLQIP--- 708
+ G Y + + + D VT+L+V++CDC + P G +
Sbjct: 637 YQNDPPF--GSYVVPITVRDRLGMSSVTSLDVTLCDCITENDCTHRVDPRIGGGGVQLGK 694
Query: 709 -AILGILGGILALLILILLLLLFLRRRAVVKEPLLPPEDDTRDNVYYYDEEGGGEE 763
AIL IL GI L+ +L L K+P + P+D + N+ + E G++
Sbjct: 695 WAILAILLGI--ALLFCILFTLVCGASGTSKQPKVIPDDLAQQNLIVSNTEAPGDD 748
>gi|13435364 desmocollin 2 isoform Dsc2a preproprotein [Homo
sapiens]
Length = 901
Score = 355 bits (911), Expect = 1e-97
Identities = 247/776 (31%), Positives = 381/776 (49%), Gaps = 49/776 (6%)
Query: 2 GPWSRSLSALLLLLQVSSWLCQEPEPCHPGFDAESYTFTVPRRHLERGRVLGRVNFEDCT 61
G W+ +L LLLL + L + C ++ T VP + L+ +++GRVN ++C
Sbjct: 8 GSWNGALCRLLLL--TLAILIFASDAC------KNVTLHVPSK-LDAEKLVGRVNLKECF 58
Query: 62 GRQRTAYFSLDTRFKVGTDGVITVKRPLRFHNPQIHFLVYAWDSTYRKFSTKVTLNTVGH 121
+ S D F++ DG + + + + F + +T + K+ +
Sbjct: 59 TAANLIHSS-DPDFQILEDGSVYTTNTILLSSEKRSFTILL-SNTENQEKKKIFVFL--- 113
Query: 122 HHRPPPHQASVSGIQAELLTFPNSSPGLRRQKRDWVIPPISCPENEKGPFPKNLVQIKSN 181
HQ V L LRR KR W P S EN GPFP L Q++S+
Sbjct: 114 -----EHQTKV------LKKRHTKEKVLRRAKRRWAPIPCSMLENSLGPFPLFLQQVQSD 162
Query: 182 KDKEGKVFYSITGQGADTPPVGVFIIERETGWLKVTEPLDRERIATYTLFSHAVSSNGNA 241
+ ++YSI G G D P +F +ER+TG L T P+DRE+ ++ + + A + +G
Sbjct: 163 TAQNYTIYYSIRGPGVDQEPRNLFYVERDTGNLYCTRPVDREQYESFEIIAFATTPDGYT 222
Query: 242 VEDPMEILITVTDQNDNKPEFTQEVFKGSVMEGALPGTSVMEVTATDADDDVNTYNAAIA 301
E P+ ++I + D+NDN P FT+E + ++ E GT+V +V ATD D+ +T + +
Sbjct: 223 PELPLPLIIKIEDENDNYPIFTEETYTFTIFENCRVGTTVGQVCATDKDEP-DTMHTRLK 281
Query: 302 YTILSQDPELPDKNMFTINRNTGVISVVTTGLDRESFPTYTLVVQAADLQGE--GLSTTA 359
Y+I+ Q P P +F+++ TGVI+ ++ LDRE Y L ++ D+ G+ GL TT+
Sbjct: 282 YSIIGQVP--PSPTLFSMHPTTGVITTTSSQLDRELIDKYQLKIKVQDMDGQYFGLQTTS 339
Query: 360 TAVITVTDTNDNPPIFNPTTYKGQVPENEANVVITTLKVTDADAPNTPAWEAVYTIL-ND 418
T +I + D ND+ P F T+Y V EN +V I + V D D NT W A YTIL +
Sbjct: 340 TCIINIDDVNDHLPTFTRTSYVTSVEENTVDVEILRVTVEDKDLVNTANWRANYTILKGN 399
Query: 419 DGGQFVVTTNPVNNDGILKTAKGLDFEAKQQYILHVAVTNVVPFEVSLT----TSTATVT 474
+ G F + T+ N+G+L K L++E KQQ IL + V N PF + STATVT
Sbjct: 400 ENGNFKIVTDAKTNEGVLCVVKPLNYEEKQQMILQIGVVNEAPFSREASPRSAMSTATVT 459
Query: 475 VDVLDVNEAPIFVPPEKRVEVSEDFGVGQEITSYTAQEPDTFMEQKITYRIWRDTANWLE 534
V+V D +E P PP + V + E+ VG Y A +P+T I Y+ D W+
Sbjct: 460 VNVEDQDEGPECNPPIQTVRMKENAEVGTTSNGYKAYDPETRSSSGIRYKKLTDPTGWVT 519
Query: 535 INPDTGAISTRAELDREDFEHVKNSTYTALIIATDNGSPVATGTGTLLLILSDVNDNAPI 594
I+ +TG+I LDRE E +KN Y ++A+D G T TGTL +IL DVNDN+P
Sbjct: 520 IDENTGSIKVFRSLDRE-AETIKNGIYNITVLASDQGG--RTCTGTLGIILQDVNDNSPF 576
Query: 595 PEPRTIFFCERNPKPQVINIIDADLPPNTSPFTAEL---THGASANWTIQYNDPTQESII 651
+T+ C+ I +D D P + PF L T W ++ + T +
Sbjct: 577 IPKKTVIICKPTMSSAEIVAVDPDEPIHGPPFDFSLESSTSEVQRMWRLKAINDTAARLS 636
Query: 652 LKPKMALEVGDYKINLKLMDNQNKDQVTTLEVSVCDCEGAAGVCRKAQPVEAGLQIP--- 708
+ G Y + + + D VT+L+V++CDC + P G +
Sbjct: 637 YQNDPPF--GSYVVPITVRDRLGMSSVTSLDVTLCDCITENDCTHRVDPRIGGGGVQLGK 694
Query: 709 -AILGILGGILALLILILLLLLFLRRRAVVKEPLLPPEDDTRDNVYYYDEEGGGEE 763
AIL IL GI L+ +L L K+P + P+D + N+ + E G++
Sbjct: 695 WAILAILLGI--ALLFCILFTLVCGASGTSKQPKVIPDDLAQQNLIVSNTEAPGDD 748
Score = 30.0 bits (66), Expect = 9.9
Identities = 20/63 (31%), Positives = 32/63 (50%), Gaps = 10/63 (15%)
Query: 812 DENLKAADTDPTAPPYDSLLVFDYEGSGSEAASLSSLNSSESDKDQDYDYLNEWGNRFKK 871
DEN K A D +L ++YEG GS A S+ SE ++ ++L+ +F+
Sbjct: 844 DENHKHAQ--------DYVLTYNYEGRGSVAGSVGC--CSERQEEDGLEFLDNLEPKFRT 893
Query: 872 LAD 874
LA+
Sbjct: 894 LAE 896
>gi|16306537 cadherin 20, type 2 preproprotein [Homo sapiens]
Length = 801
Score = 353 bits (905), Expect = 5e-97
Identities = 263/781 (33%), Positives = 397/781 (50%), Gaps = 61/781 (7%)
Query: 136 QAELLTFPNSSP-GLRRQKRDWVIPPISCPENEKGPFPKNLVQIKSNKDK-EGKVFYSIT 193
Q EL + P +R KR WV E G P + ++ S+ D+ +G + Y ++
Sbjct: 40 QGELEALLSDKPQSHQRTKRSWVWNQFFVLEEYTGTDPLYVGKLHSDMDRGDGSIKYILS 99
Query: 194 GQGADTPPVGVFIIERETGWLKVTEPLDRERIATYTLFSHAVSSN-GNAVEDPMEILITV 252
G+GA VF I+ TG + + LDRE A YTL + A+ G +E E +I +
Sbjct: 100 GEGAGI----VFTIDDTTGDIHAIQRLDREERAQYTLRAQALDRRTGRPMEPESEFIIKI 155
Query: 253 TDQNDNKPEFTQEVFKGSVMEGALPGTSVMEVTATDADDDVNTYNAAIAYTILSQDPELP 312
D NDN+P+F + +V E + GTSV++VTATDADD +A + Y+IL P
Sbjct: 156 QDINDNEPKFLDGPYVATVPEMSPVGTSVIQVTATDADDPTYGNSARVVYSILQGQP--- 212
Query: 313 DKNMFTINRNTGVISVVTTGLDRESFPTYTLVVQAADLQGE--GLSTTATAVITVTDTND 370
F+++ TGVI +DRE+ Y +++QA D+ G+ GL+ T T IT++D ND
Sbjct: 213 ---YFSVDSKTGVIRTALMNMDREAKEYYEVIIQAKDMGGQLGGLAGTTTVNITLSDVND 269
Query: 371 NPPIFNPTTYKGQVPENEANVVITTLKVTDADAPNTPAWEAVYTILNDDGGQ-FVVTTNP 429
NPP F Y+ V E+ A + T +V D E YTI++ DG F ++T+P
Sbjct: 270 NPPRFPQKHYQMSVLES-APISSTVGRVFAKDLDEGINAEMKYTIVDGDGADAFDISTDP 328
Query: 430 VNNDGILKTAKGLDFEAKQQYILHVA---------VTNVVPFEVSLTTSTATVTVDVLDV 480
GI+ K L FE+K+ Y L V N+ PF+ T TV + V DV
Sbjct: 329 NFQVGIITVKKPLSFESKKSYTLKVEGANPHLEMRFLNLGPFQ-----DTTTVHISVEDV 383
Query: 481 NEAPIFVPPEKRVEVSEDFGVGQEITSYTAQEPDTFMEQKITYRIWR--DTANWLEINPD 538
+E P+F P VEV ED +G I +A++PD I Y I R D + ++
Sbjct: 384 DEPPVFEPGFYFVEVPEDVAIGTTIQIISAKDPDV-TNNSIRYSIDRSSDPGRFFYVDIT 442
Query: 539 TGAISTRAELDREDFEHVKNSTYTALIIATDNGSPVATGTGTLLLILSDVNDNAP-IPEP 597
TGA+ T LDRE+F S + ++A + +P G+ + + + DVNDNAP P
Sbjct: 443 TGALMTARPLDREEF-----SWHNITVLAMEMNNPSQVGSVPVTIKVLDVNDNAPEFPRF 497
Query: 598 RTIFFCERNPKPQVI---NIIDADLPPNTSPFTAELTHGAS--ANWTIQYNDPTQESIIL 652
F CE Q+I + +D D P N F L A+ N+TI+ N I+
Sbjct: 498 YEAFVCENAKAGQLIQTVSAVDQDDPRNGQHFYYSLAPEAANNPNFTIRDNQDNTARILT 557
Query: 653 KPKMALEVGDYKINLKLMDNQNKDQVT----TLEVSVCDCEGAAGVCR---KAQPVEAGL 705
+ + +L ++ + V TL + VC C+ V +A + L
Sbjct: 558 RRSGFRQQEQSVFHLPILIADSGQPVLSSTGTLTIQVCSCDDDGHVMSCSPEAYMLPVSL 617
Query: 706 QIPAILGILGGILALLILILLLLLFLRRRAVVKEP-LLPPEDDTRDNVYYYDEEGGGEED 764
A++ IL I LL+L+LL+L R R K+P ++ E++ +N+ YD+EGGGEED
Sbjct: 618 SRGALIAILACIFVLLVLVLLILSMRRHR---KQPYIIDDEENIHENIVRYDDEGGGEED 674
Query: 765 QD-FDLSQLHRGLDARPEV---TRNDVAPTLMSVPRYLPRP-ANPDEIGNFIDENLKAAD 819
+ FD++ + +A+ TR D+ P + S+ RY+P+ A + +++ L AD
Sbjct: 675 TEAFDIAAMWNPREAQAGAAPKTRQDMLPEIESLSRYVPQTCAVNSTVHSYVLAKLYEAD 734
Query: 820 TDPTAPPYDSLLVFDYEGSGSEAASLSSLNSSESDKDQDYDYLNEWGNRFKKLADMYGGG 879
D APP+DSL + +EG GS A SLSSL S+ SD +Q +D+L +WG RF+KLA++YG
Sbjct: 735 MDLWAPPFDSLQTYMFEGDGSVAGSLSSLQSATSDSEQSFDFLTDWGPRFRKLAELYGAS 794
Query: 880 E 880
E
Sbjct: 795 E 795
>gi|148539848 desmocollin 3 isoform Dsc3b preproprotein [Homo
sapiens]
Length = 839
Score = 339 bits (870), Expect = 6e-93
Identities = 238/728 (32%), Positives = 364/728 (50%), Gaps = 37/728 (5%)
Query: 46 LERGRVLGRVNFEDCTGRQRTAYFSLDTRFKVGTDGVITVKRPLRFHNPQIHFLVYAWDS 105
LE +++GRVN E+C R S D F+V DG + R + + + F + W S
Sbjct: 43 LEADKIIGRVNLEECF-RSADLIRSSDPDFRVLNDGSVYTARAVALSDKKRSFTI--WLS 99
Query: 106 TYRKFSTKVTLNTVGHHHRPPPHQASVSGIQAELLTFPNSSPGLRRQKRDWVIPPISCPE 165
RK + K + HQ VS + T LRR KR W P S E
Sbjct: 100 DKRKQTQKEVTVLL-------EHQKKVSKTRHTRETV------LRRAKRRWAPIPCSMQE 146
Query: 166 NEKGPFPKNLVQIKSNKDKEGKVFYSITGQGADTPPVGVFIIERETGWLKVTEPLDRERI 225
N GPFP L Q++S+ + VFYSI+G+G D P+ +F IER+TG L T P+DRE
Sbjct: 147 NSLGPFPLFLQQVESDAAQNYTVFYSISGRGVDKEPLNLFYIERDTGNLFCTRPVDREEY 206
Query: 226 ATYTLFSHAVSSNGNAVEDPMEILITVTDQNDNKPEFTQEVFKGSVMEGALPGTSVMEVT 285
+ L ++A +++G + + P+ + I V D+NDN P FT+ ++ V+E + PGT+V V
Sbjct: 207 DVFDLIAYASTADGYSADLPLPLPIRVEDENDNHPVFTEAIYNFEVLESSRPGTTVGVVC 266
Query: 286 ATDADDDVNTYNAAIAYTILSQDPELPDKNMFTINRNTGVISVVTTGLDRESFPTYTLVV 345
ATD D+ +T + + Y+IL Q P P +F+++ +TGVI+ V+ LDRE Y+L++
Sbjct: 267 ATDRDEP-DTMHTRLKYSILQQTPRSP--GLFSVHPSTGVITTVSHYLDREVVDKYSLIM 323
Query: 346 QAADLQGE--GLSTTATAVITVTDTNDNPPIFNPTTYKGQVPENEANVVITTLKVTDADA 403
+ D+ G+ GL T+T +ITVTD+NDN P F Y+ V EN NV I + + D D
Sbjct: 324 KVQDMDGQFFGLIGTSTCIITVTDSNDNAPTFRQNAYEAFVEENAFNVEILRIPIEDKDL 383
Query: 404 PNTPAWEAVYTIL-NDDGGQFVVTTNPVNNDGILKTAKGLDFEAKQQYILHVAVTNVVPF 462
NT W +TIL ++ G F ++T+ N+G+L K L++E +Q L + V N PF
Sbjct: 384 INTANWRVNFTILKGNENGHFKISTDKETNEGVLSVVKPLNYEENRQVNLEIGVNNEAPF 443
Query: 463 EVSLTTST----ATVTVDVLDVNEAPIFVPPEKRVEVSEDFGVGQEITSYTAQEPDTFME 518
+ T A VTV V D++E P P + V + E+ VG +I Y A +P+
Sbjct: 444 ARDIPRVTALNRALVTVHVRDLDEGPECTPAAQYVRIKENLAVGSKINGYKAYDPENRNG 503
Query: 519 QKITYRIWRDTANWLEINPDTGAISTRAELDREDFEHVKNSTYTALIIATDNGSPVATGT 578
+ Y+ D W+ I+ +G+I T LDRE E KN Y ++A D + T
Sbjct: 504 NGLRYKKLHDPKGWITIDEISGSIITSKILDRE-VETPKNELYNITVLAIDKDD--RSCT 560
Query: 579 GTLLLILSDVNDNAPIPEPRTIFFCERNPKPQVINIIDADLPPNTSPFTAELTHGA---S 635
GTL + + DVNDN P + C+ I +D D P + +PF L + + S
Sbjct: 561 GTLAVNIEDVNDNPPEILQEYVVICKPKMGYTDILAVDPDEPVHGAPFYFSLPNTSPEIS 620
Query: 636 ANWTIQYNDPTQESIILKPKMALEVGDYKINLKLMDNQNKDQVTTLEVSVCDCEGAAGVC 695
W++ + T + + + +Y I + + D + L V++C+C
Sbjct: 621 RLWSLTKVNDTAARLSYQKNAGFQ--EYTIPITVKDRAGQAATKLLRVNLCECTHPTQCR 678
Query: 696 RKAQPVEAGLQIPAILGILGGILALLILILLLLLFLRRRAVVKEPLLPPEDDTRDNVYYY 755
++ L AIL IL GI ALL +LL L+ A + PED + N+
Sbjct: 679 ATSRSTGVILGKWAILAILLGI-ALLFSVLLTLVCGVFGATKGKRF--PEDLAQQNLIIS 735
Query: 756 DEEGGGEE 763
+ E G++
Sbjct: 736 NTEAPGDD 743
>gi|148539846 desmocollin 3 isoform Dsc3a preproprotein [Homo
sapiens]
Length = 896
Score = 339 bits (870), Expect = 6e-93
Identities = 238/728 (32%), Positives = 364/728 (50%), Gaps = 37/728 (5%)
Query: 46 LERGRVLGRVNFEDCTGRQRTAYFSLDTRFKVGTDGVITVKRPLRFHNPQIHFLVYAWDS 105
LE +++GRVN E+C R S D F+V DG + R + + + F + W S
Sbjct: 43 LEADKIIGRVNLEECF-RSADLIRSSDPDFRVLNDGSVYTARAVALSDKKRSFTI--WLS 99
Query: 106 TYRKFSTKVTLNTVGHHHRPPPHQASVSGIQAELLTFPNSSPGLRRQKRDWVIPPISCPE 165
RK + K + HQ VS + T LRR KR W P S E
Sbjct: 100 DKRKQTQKEVTVLL-------EHQKKVSKTRHTRETV------LRRAKRRWAPIPCSMQE 146
Query: 166 NEKGPFPKNLVQIKSNKDKEGKVFYSITGQGADTPPVGVFIIERETGWLKVTEPLDRERI 225
N GPFP L Q++S+ + VFYSI+G+G D P+ +F IER+TG L T P+DRE
Sbjct: 147 NSLGPFPLFLQQVESDAAQNYTVFYSISGRGVDKEPLNLFYIERDTGNLFCTRPVDREEY 206
Query: 226 ATYTLFSHAVSSNGNAVEDPMEILITVTDQNDNKPEFTQEVFKGSVMEGALPGTSVMEVT 285
+ L ++A +++G + + P+ + I V D+NDN P FT+ ++ V+E + PGT+V V
Sbjct: 207 DVFDLIAYASTADGYSADLPLPLPIRVEDENDNHPVFTEAIYNFEVLESSRPGTTVGVVC 266
Query: 286 ATDADDDVNTYNAAIAYTILSQDPELPDKNMFTINRNTGVISVVTTGLDRESFPTYTLVV 345
ATD D+ +T + + Y+IL Q P P +F+++ +TGVI+ V+ LDRE Y+L++
Sbjct: 267 ATDRDEP-DTMHTRLKYSILQQTPRSP--GLFSVHPSTGVITTVSHYLDREVVDKYSLIM 323
Query: 346 QAADLQGE--GLSTTATAVITVTDTNDNPPIFNPTTYKGQVPENEANVVITTLKVTDADA 403
+ D+ G+ GL T+T +ITVTD+NDN P F Y+ V EN NV I + + D D
Sbjct: 324 KVQDMDGQFFGLIGTSTCIITVTDSNDNAPTFRQNAYEAFVEENAFNVEILRIPIEDKDL 383
Query: 404 PNTPAWEAVYTIL-NDDGGQFVVTTNPVNNDGILKTAKGLDFEAKQQYILHVAVTNVVPF 462
NT W +TIL ++ G F ++T+ N+G+L K L++E +Q L + V N PF
Sbjct: 384 INTANWRVNFTILKGNENGHFKISTDKETNEGVLSVVKPLNYEENRQVNLEIGVNNEAPF 443
Query: 463 EVSLTTST----ATVTVDVLDVNEAPIFVPPEKRVEVSEDFGVGQEITSYTAQEPDTFME 518
+ T A VTV V D++E P P + V + E+ VG +I Y A +P+
Sbjct: 444 ARDIPRVTALNRALVTVHVRDLDEGPECTPAAQYVRIKENLAVGSKINGYKAYDPENRNG 503
Query: 519 QKITYRIWRDTANWLEINPDTGAISTRAELDREDFEHVKNSTYTALIIATDNGSPVATGT 578
+ Y+ D W+ I+ +G+I T LDRE E KN Y ++A D + T
Sbjct: 504 NGLRYKKLHDPKGWITIDEISGSIITSKILDRE-VETPKNELYNITVLAIDKDD--RSCT 560
Query: 579 GTLLLILSDVNDNAPIPEPRTIFFCERNPKPQVINIIDADLPPNTSPFTAELTHGA---S 635
GTL + + DVNDN P + C+ I +D D P + +PF L + + S
Sbjct: 561 GTLAVNIEDVNDNPPEILQEYVVICKPKMGYTDILAVDPDEPVHGAPFYFSLPNTSPEIS 620
Query: 636 ANWTIQYNDPTQESIILKPKMALEVGDYKINLKLMDNQNKDQVTTLEVSVCDCEGAAGVC 695
W++ + T + + + +Y I + + D + L V++C+C
Sbjct: 621 RLWSLTKVNDTAARLSYQKNAGFQ--EYTIPITVKDRAGQAATKLLRVNLCECTHPTQCR 678
Query: 696 RKAQPVEAGLQIPAILGILGGILALLILILLLLLFLRRRAVVKEPLLPPEDDTRDNVYYY 755
++ L AIL IL GI ALL +LL L+ A + PED + N+
Sbjct: 679 ATSRSTGVILGKWAILAILLGI-ALLFSVLLTLVCGVFGATKGKRF--PEDLAQQNLIIS 735
Query: 756 DEEGGGEE 763
+ E G++
Sbjct: 736 NTEAPGDD 743
Score = 33.5 bits (75), Expect = 0.89
Identities = 18/50 (36%), Positives = 27/50 (54%), Gaps = 2/50 (4%)
Query: 825 PPYDSLLVFDYEGSGSEAASLSSLNSSESDKDQDYDYLNEWGNRFKKLAD 874
P D +L ++YEG GS A S+ SE ++ D+LN +F LA+
Sbjct: 844 PSQDYVLTYNYEGRGSPAGSVGC--CSEKQEEDGLDFLNNLEPKFITLAE 891
>gi|32880203 cadherin-like 24 isoform 2 [Homo sapiens]
Length = 781
Score = 330 bits (846), Expect = 4e-90
Identities = 254/763 (33%), Positives = 374/763 (49%), Gaps = 51/763 (6%)
Query: 147 PGLRRQKRDWVIPPISCPENEKGPFPKNLVQIKSNKDK-EGKVFYSITGQGADTPPVGVF 205
P L R +R WV E GP P + ++ S+ D+ EG+ Y +TG+GA T VF
Sbjct: 37 PALLRTRRSWVWNQFFVIEEYAGPEPVLIGKLHSDVDRGEGRTKYLLTGEGAGT----VF 92
Query: 206 IIERETGWLKVTEPLDRERIATYTLFSHAVSSNGNA-VEDPMEILITVTDQNDNKPEFTQ 264
+I+ TG + VT+ LDRE A Y L + AV N +E P E +I V D NDN P F
Sbjct: 93 VIDEATGNIHVTKSLDREEKAQYVLLAQAVDRASNRPLEPPSEFIIKVQDINDNPPIFPL 152
Query: 265 EVFKGSVMEGALPGTSVMEVTATDADDDVNTYNAAIAYTILSQDPELPDKNMFTINRNTG 324
+ +V E + GTSV++VTA DADD +A + YT+L P F+++ TG
Sbjct: 153 GPYHATVPEMSNVGTSVIQVTAHDADDPSYGNSAKLVYTVLDGLP------FFSVDPQTG 206
Query: 325 VISVVTTGLDRESFPTYTLVVQAADLQGE--GLSTTATAVITVTDTNDNPPIFNPTTYKG 382
V+ +DRE+ + +V+QA D+ G GLS + T +T++D NDNPP F + Y+
Sbjct: 207 VVRTAIPNMDRETQEEFLVVIQAKDMGGHMGGLSGSTTVTVTLSDVNDNPPKFPQSLYQF 266
Query: 383 QVPENEA-NVVITTLKVTDADAPNTPAWEAVYTILNDDGGQ-FVVTTNPVNNDGILKTAK 440
V E ++ L+ D D + Y+IL+ +G + F ++T+ DG+L K
Sbjct: 267 SVVETAGPGTLVGRLRAQDPDLGDNALM--AYSILDGEGSEAFSISTDLQGRDGLLTVRK 324
Query: 441 GLDFEAKQQYILHVAVTNVVPFEVSLTTS----TATVTVDVLDVNEAPIFVPPEKRVEVS 496
LDFE+++ Y V TN + L A+V V V D E P F + V
Sbjct: 325 PLDFESQRSYSFRVEATNTLIDPAYLRRGPFKDVASVRVAVQDAPEPPAFTQAAYHLTVP 384
Query: 497 EDFGVGQEITSYTAQEPDTFMEQKITYRIW--RDTANWLEINPDTGAISTRAELDREDFE 554
E+ G + +A + D+ I Y I D I P+ G I T A LDRE
Sbjct: 385 ENKAPGTLVGQISAADLDS-PASPIRYSILPHSDPERCFSIQPEEGTIHTAAPLDRE--- 440
Query: 555 HVKNSTYTALIIATDNGSPVATGTGTLLLILSDVNDNAP-IPEPRTIFFCERNPKPQVIN 613
+ + ++AT+ S + + D NDNAP + EP F C+ Q+I
Sbjct: 441 --ARAWHNLTVLATELDSSAQASRVQVAIQTLDENDNAPQLAEPYDTFVCDSAAPGQLIQ 498
Query: 614 II---DADLPPNTSPFTAELTHGASANWTIQYNDPTQESIILKPKMAL-EVGDYKINLKL 669
+I D D N+S + + G AN+T+Q N S++L + A Y + ++L
Sbjct: 499 VIRALDRDEVGNSSHVSFQGPLGPDANFTVQDNRDGSASLLLPSRPAPPRHAPYLVPIEL 558
Query: 670 MD--NQNKDQVTTLEVSVCDCE--GAAGVC-RKAQPVEAGLQIPAILGILGGILALLILI 724
D T+ VSVC C+ G+ C +A AGL A+L I+ + ALL L+
Sbjct: 559 WDWGQPALSSTATVTVSVCRCQPDGSVASCWPEAHLSAAGLSTGALLAIITCVGALLALV 618
Query: 725 LLLLLFLRRRAVVKEPLLPPEDDTRDNVYYYDEEGGGEEDQD-FDLSQLHRGLDARPEV- 782
+L + R++ + ++ E+D R+N+ YD+EGGGEED + FD++ L A P
Sbjct: 619 VLFVALRRQKQ--EALMVLEEEDVRENIITYDDEGGGEEDTEAFDITALQNPDGAAPPAP 676
Query: 783 ---TRNDVAPTLMSVPRYLPRPANPDEIGNFIDENLKAADTDPTAPPYDSLLVFDYEGSG 839
R DV P V R PRP P ++ + L+ AD DP PPYDS+ V+ YEG G
Sbjct: 677 GPPARRDVLPRAR-VSRQ-PRPPGPADVAQLLALRLREADEDPGVPPYDSVQVYGYEGRG 734
Query: 840 SEAASLSSLNSSE--SDKDQDYDYLNEWGNRFKKLADMYGGGE 880
S SLSSL S + L++WG F+ LA++YG E
Sbjct: 735 SSCGSLSSLGSGSEAGGAPGPAEPLDDWGPLFRTLAELYGAKE 777
>gi|32880206 cadherin-like 24 isoform 1 [Homo sapiens]
Length = 819
Score = 319 bits (817), Expect = 8e-87
Identities = 259/801 (32%), Positives = 378/801 (47%), Gaps = 89/801 (11%)
Query: 147 PGLRRQKRDWVIPPISCPENEKGPFPKNLVQIKSNKDK-EGKVFYSITGQGADTPPVGVF 205
P L R +R WV E GP P + ++ S+ D+ EG+ Y +TG+GA T VF
Sbjct: 37 PALLRTRRSWVWNQFFVIEEYAGPEPVLIGKLHSDVDRGEGRTKYLLTGEGAGT----VF 92
Query: 206 IIERETGWLKVTEPLDRERIATYTLFSHAVSSNGNA-VEDPMEILITVTDQNDNKPEFTQ 264
+I+ TG + VT+ LDRE A Y L + AV N +E P E +I V D NDN P F
Sbjct: 93 VIDEATGNIHVTKSLDREEKAQYVLLAQAVDRASNRPLEPPSEFIIKVQDINDNPPIFPL 152
Query: 265 EVFKGSVMEGALPGTSVMEVTATDADDDVNTYNAAIAYTILSQDPELPDKNMFTINRNTG 324
+ +V E + GTSV++VTA DADD +A + YT+L P F+++ TG
Sbjct: 153 GPYHATVPEMSNVGTSVIQVTAHDADDPSYGNSAKLVYTVLDGLP------FFSVDPQTG 206
Query: 325 VISVVTTGLDRESFPTYTLVVQAADLQGE--GLSTTATAVITVTDTNDNPPIFNPTTYKG 382
V+ +DRE+ + +V+QA D+ G GLS + T +T++D NDNPP F + Y+
Sbjct: 207 VVRTAIPNMDRETQEEFLVVIQAKDMGGHMGGLSGSTTVTVTLSDVNDNPPKFPQSLYQF 266
Query: 383 QVPENEA-NVVITTLKVTDADAPNTPAWEAVYTILNDDGGQ-FVVTTNPVNNDGILKTAK 440
V E ++ L+ D D + Y+IL+ +G + F ++T+ DG+L K
Sbjct: 267 SVVETAGPGTLVGRLRAQDPDLGDNAL--MAYSILDGEGSEAFSISTDLQGRDGLLTVRK 324
Query: 441 GLDFEAKQQYILHVAVTNVVPFEVSLT----TSTATVTVDVLDVNEAPIFVPPEKRVEVS 496
LDFE+++ Y V TN + L A+V V V D E P F + V
Sbjct: 325 PLDFESQRSYSFRVEATNTLIDPAYLRRGPFKDVASVRVAVQDAPEPPAFTQAAYHLTVP 384
Query: 497 EDFGVGQEITSYTAQEPDTFMEQKITYRI--WRDTANWLEINPDTGAISTRAELDREDFE 554
E+ G + +A + D+ I Y I D I P+ G I T A LDRE
Sbjct: 385 ENKAPGTLVGQISAADLDS-PASPIRYSILPHSDPERCFSIQPEEGTIHTAAPLDRE--- 440
Query: 555 HVKNSTYTALIIATDNG--------------------------SPVATGTG--------- 579
+ + ++AT+ G SPV + G
Sbjct: 441 --ARAWHNLTVLATELGWSWGPERGWVPLLVAEWSAPAAPPQRSPVGSAVGIPQDSSAQA 498
Query: 580 ---TLLLILSDVNDNAP-IPEPRTIFFCERNPKPQVINII---DADLPPNTSPFTAELTH 632
+ + D NDNAP + EP F C+ Q+I +I D D N+S + +
Sbjct: 499 SRVQVAIQTLDENDNAPQLAEPYDTFVCDSAAPGQLIQVIRALDRDEVGNSSHVSFQGPL 558
Query: 633 GASANWTIQYNDPTQESIILKPKMA-LEVGDYKINLKLMD--NQNKDQVTTLEVSVCDC- 688
G AN+T+Q N S++L + A Y + ++L D T+ VSVC C
Sbjct: 559 GPDANFTVQDNRDGSASLLLPSRPAPPRHAPYLVPIELWDWGQPALSSTATVTVSVCRCQ 618
Query: 689 -EGAAGVC-RKAQPVEAGLQIPAILGILGGILALLILILLLLLFLRRRAVVKEPLLPPED 746
+G+ C +A AGL A+L I+ + ALL L++L + RR + ++ E+
Sbjct: 619 PDGSVASCWPEAHLSAAGLSTGALLAIITCVGALLALVVLFVAL--RRQKQEALMVLEEE 676
Query: 747 DTRDNVYYYDEEGGGEEDQD-FDLSQLHRGLDARPEV----TRNDVAPTLMSVPRYLPRP 801
D R+N+ YD+EGGGEED + FD++ L A P R DV P V R PRP
Sbjct: 677 DVRENIITYDDEGGGEEDTEAFDITALQNPDGAAPPAPGPPARRDVLPR-ARVSRQ-PRP 734
Query: 802 ANPDEIGNFIDENLKAADTDPTAPPYDSLLVFDYEGSGSEAASLSSLNSSE--SDKDQDY 859
P ++ + L+ AD DP PPYDS+ V+ YEG GS SLSSL S
Sbjct: 735 PGPADVAQLLALRLREADEDPGVPPYDSVQVYGYEGRGSSCGSLSSLGSGSEAGGAPGPA 794
Query: 860 DYLNEWGNRFKKLADMYGGGE 880
+ L++WG F+ LA++YG E
Sbjct: 795 EPLDDWGPLFRTLAELYGAKE 815
>gi|12656655 cadherin 19, type 2 preproprotein [Homo sapiens]
Length = 772
Score = 310 bits (793), Expect = 5e-84
Identities = 249/754 (33%), Positives = 380/754 (50%), Gaps = 55/754 (7%)
Query: 151 RQKRDWVIPPISCPENEKGPFPKNLVQIKSNKDKEGKVF-YSITGQGADTPPVGVFIIER 209
R KR WV PE E ++ Q++S+ D F Y + G GA + FII+
Sbjct: 40 RVKRGWVWNQFFVPE-EMNTTSHHIGQLRSDLDNGNNSFQYKLLGAGAGS----TFIIDE 94
Query: 210 ETGWLKVTEPLDRERIATYTLFSHAVS-SNGNAVEDPMEILITVTDQNDNKPEFTQEVFK 268
TG + + LDRE + Y L + + + G AVE E +I V+D NDN+P+F E ++
Sbjct: 95 RTGDIYAIQKLDREERSLYILRAQVIDIATGRAVEPESEFVIKVSDINDNEPKFLDEPYE 154
Query: 269 GSVMEGALPGTSVMEVTATDADDDVNTYNAAIAYTILSQDPELPDKNMFTINRNTGVISV 328
V E + GT V++VTA+DADD + NA + Y++L P F++ TGVI +
Sbjct: 155 AIVPEMSPEGTLVIQVTASDADDPSSGNNARLLYSLLQGQP------YFSVEPTTGVIRI 208
Query: 329 VTTGLDRESFPTYTLVVQAADLQGE--GLSTTATAVITVTDTNDNPPIFNPTTYKGQVPE 386
++ +DRE Y +++QA D+ G+ LS T + +I ++D NDN PIF + Y+ V E
Sbjct: 209 -SSKMDRELQDEYWVIIQAKDMIGQPGALSGTTSVLIKLSDVNDNKPIFKESLYRLTVSE 267
Query: 387 NE-ANVVITTLKVTDADAPNTPAWEAVYTILNDDGGQFVVTTNPVNNDGILKTAKGLDFE 445
+ I T+ D D E Y+I DD F + TN +GI+ K +DFE
Sbjct: 268 SAPTGTSIGTIMAYDNDIGENA--EMDYSIEEDDSQTFDIITNHETQEGIVILKKKVDFE 325
Query: 446 AKQQYILHVAVTNV-VPFEVS---LTTSTATVTVDVLDVNEAPIFVPPEKRVEVSEDFGV 501
+ Y + V N VP ++ ST + + V DV+E P+F+ P EV E+
Sbjct: 326 HQNHYGIRAKVKNHHVPEQLMKYHTEASTTFIKIQVEDVDEPPLFLLPYYVFEVFEETPQ 385
Query: 502 GQEITSYTAQEPDTFMEQKITYRIWRDTANWLEINPDTGAISTRAELDREDFEHVKNSTY 561
G + +A +PD + I Y I R IN D G I+T LDRE ++ Y
Sbjct: 386 GSFVGVVSATDPDN-RKSPIRYSITRSKV--FNIN-DNGTITTSNSLDREI-----SAWY 436
Query: 562 TALIIATDNGSPVATGTGTLLLILSDVNDNAP-IPEPRTIFFCERNPKPQVINII----- 615
I AT+ + + L + + ++ND+AP + + CE QVI I
Sbjct: 437 NLSITATEKYNIEQISSIPLYVQVLNINDHAPEFSQYYETYVCENAGSGQVIQTISAVDR 496
Query: 616 DADLPPNTSPFTAELTHGASANWTIQYNDPTQESIILKPKMALEVGD---YKINLKLMDN 672
D + + F + ++++TI N ++IL + + + + I++ + DN
Sbjct: 497 DESIEEHHFYFNLSVEDTNNSSFTIIDNQDNT-AVILTNRTGFNLQEEPVFYISILIADN 555
Query: 673 --QNKDQVTTLEVSVCDC--EGAAGVCRKAQPV-EAGLQIPAILGILGGILALLILILLL 727
+ TL + VCDC G+ C+ + V G + I+ IL I+ + I L
Sbjct: 556 GIPSLTSTNTLTIHVCDCGDSGSTQTCQYQELVLSMGFKTEVIIAILICIMIIFGFIFLT 615
Query: 728 LLFLRRRAVVKEPLLPPE-DDTRDNVYYYDEEGGGEEDQD-FDLSQLHRGLDARPEVTRN 785
L +RR K+ L P + +D R+N++ YD+EGGGEED + FD+++L R TR
Sbjct: 616 LGLKQRR---KQILFPEKSEDFRENIFQYDDEGGGEEDTEAFDIAELRSSTIMRERKTRK 672
Query: 786 DVAPTLMSVPRYLPRPANPDE--IGNFIDENLKAADTDPTAPPYDSLLVFDYEGSGSEAA 843
+ + S+ R + PD FI E L+ A+TDP APP+DSL + +EG+GS A
Sbjct: 673 TTSAEIRSLYRQSLQ-VGPDSAIFRKFILEKLEEANTDPCAPPFDSLQTYAFEGTGSLAG 731
Query: 844 SLSSLNSSESDKDQDYDYLNEWGNRFKKLADMYG 877
SLSSL S+ SD+D+ YDYLNE G RFK+LA M+G
Sbjct: 732 SLSSLESAVSDQDESYDYLNELGPRFKRLACMFG 765
>gi|29570800 cadherin-like 26 isoform a [Homo sapiens]
Length = 832
Score = 307 bits (787), Expect = 2e-83
Identities = 212/641 (33%), Positives = 325/641 (50%), Gaps = 40/641 (6%)
Query: 149 LRRQKRDWVIPPISCPENEKGPFPKNLVQIKSNKDKEGKVFYSITGQGADT-PPVGVFII 207
LRR KR WVI + E + GPFPK + ++ +N + Y I+G G D P +G+F +
Sbjct: 49 LRRSKRRWVITTLELEEEDPGPFPKLIGELFNNMSYNMSLMYLISGPGVDEYPEIGLFSL 108
Query: 208 E-RETGWLKVTEPLDRERIATYTLFSHAVS-SNGNAVEDPMEILITVTDQNDNKPEFTQE 265
E E G + V P+DRE ++T++ V S G V+ + I ++D ND+ P+F ++
Sbjct: 109 EDHENGRIYVHRPVDREMTPSFTVYFDVVERSTGKIVDTSLIFNIRISDVNDHAPQFPEK 168
Query: 266 VFKGSVMEGALPGTSVMEVTATDADDDVNTYNAAIAYTILSQDPELPDKNMFTINRNTGV 325
F +V E G + ++ A D D++ NT N+ + Y ++SQ P L + F ++R +G
Sbjct: 169 EFNITVQENQSAGQPIFQMLAVDLDEE-NTPNSQVLYFLISQTPLLKESG-FRVDRLSGE 226
Query: 326 ISVVTTGLDRESFPTYTLVVQAADLQGEGLSTTATAVITVTDTNDNPPIFNPTTYKGQVP 385
I + + LD E+ P +TL+++A D LS+T T + V + N++ P F YK Q+P
Sbjct: 227 IRL-SGCLDYETAPQFTLLIRARDCGEPSLSSTTTVHVDVQEGNNHRPAFTQENYKVQIP 285
Query: 386 ENEANVVITTLKVTDADAPNTPAWEAVYTILN-DDGGQFVVTTNPVNNDGILKTAKGLDF 444
E A+ + L V D D+P T AW A + IL+ ++ G F ++T+P N+GIL K LD+
Sbjct: 286 EGRASQGVLRLLVQDRDSPFTSAWRAKFNILHGNEEGHFDISTDPETNEGILNVIKPLDY 345
Query: 445 EAKQQYILHVAVTNVVPF---------EVSLTTSTATVTVDVLDVNEAPIFVPPEKRVEV 495
E + L + V N ++ATV+V V D N+ P F P V
Sbjct: 346 ETRPAQSLIIVVENEERLVFCERGKLQPPRKAAASATVSVQVTDANDPPAFHPQSFIVNK 405
Query: 496 SEDFGVGQEITSYTAQEPDTFMEQKITYRIWRDTANWLEINPDTGAISTRAELDREDFEH 555
E G + ++ A +PD+ +I Y + D ANW+ ++ ++G + T +DRE H
Sbjct: 406 EEGARPGTLLGTFNAMDPDS----QIRYELVHDPANWVSVDKNSGVVITVEPIDRES-PH 460
Query: 556 VKNSTYTALIIATDNGSPVATGTGTLLLILSDVNDNAPIPEPRTIFF--CERN-PKPQVI 612
V NS Y +I A D+G P T TGTL+L LSD+NDN P PR+ + CE +P I
Sbjct: 461 VNNSFYVIIIHAVDDGFPPQTATGTLMLFLSDINDNVPTLRPRSRYMEVCESAVHEPLHI 520
Query: 613 NIIDADLPPNTSPFTAELTH---GASANWTIQYNDPTQESIILKPKMALEVGDYKINLKL 669
D DL P + PFT EL + A W + N +S+ L +L G+Y + L +
Sbjct: 521 EAEDPDLEPFSDPFTFELDNTWGNAEDTWKLGRN--WGQSVELLTLRSLPRGNYLVPLFI 578
Query: 670 MDNQNKDQVTTLEVSVCDCEGAAGV-CRKAQPVEAGLQIPAILGILGGILALLILILLLL 728
D Q Q T+ V +C C A+G+ C + E GL + A+ + +AL + L
Sbjct: 579 GDKQGLSQKQTVHVRICPC--ASGLTCVELADAEVGLHVGALFPVCAAFVALAV----AL 632
Query: 729 LFLRRRAVVKEP----LLPPEDDTRDNVYYYDEEGGGEEDQ 765
LFL R V EP D+ + Y+ E G Q
Sbjct: 633 LFLLRCYFVLEPKRHGCSVSNDEGHQTLVMYNAESKGTSAQ 673
>gi|166362713 cadherin 5, type 2 preproprotein [Homo sapiens]
Length = 784
Score = 306 bits (785), Expect = 4e-83
Identities = 261/773 (33%), Positives = 376/773 (48%), Gaps = 79/773 (10%)
Query: 147 PGLRRQKRDWVIPPISCPENEKGPFPKNLVQIKSNKDKEGKVFYSITGQGADTPPVGVFI 206
P RRQKRDW+ + E + P ++ +IKS+ ++ Y + G+ VF
Sbjct: 40 PTHRRQKRDWIWNQMHIDEEKNTSLPHHVGKIKSSVSRKNAK-YLLKGEYVGK----VFR 94
Query: 207 IERETGWLKVTEPLDRERIATYTLFSHAVSSN-GNAVEDPMEILITVTDQNDNKPEFTQE 265
++ ETG + E LDRE I+ Y L + V + G +E P I V D NDN P FT
Sbjct: 95 VDAETGDVFAIERLDRENISEYHLTAVIVDKDTGENLETPSSFTIKVHDVNDNWPVFTHR 154
Query: 266 VFKGSVMEGALPGTSVMEVTATDADDDVNTYNAAIAYTILSQDPELPDKNMFTINRNTGV 325
+F SV E + GTSV+ VTA DADD +A++ Y IL K F I+ N+G
Sbjct: 155 LFNASVPESSAVGTSVISVTAVDADDPTVGDHASVMYQILK------GKEYFAID-NSGR 207
Query: 326 ISVVTTGLDRESFPTYTLVVQAADLQG-EGLSTTATAVITVTDTNDNPPIFNPTTYKGQV 384
I +T LDRE Y +VV+A D QG G S TAT ++T+ D NDN P F T Y V
Sbjct: 208 IITITKSLDREKQARYEIVVEARDAQGLRGDSGTATVLVTLQDINDNFPFFTQTKYTFVV 267
Query: 385 PEN-EANVVITTLKVTDADAPNTPAWEAVYTILNDD-GGQFVVTTNPVNNDGILKTAKGL 442
PE+ + +L V D D P + Y+IL D F + TNP +N+GI+K K L
Sbjct: 268 PEDTRVGTSVGSLFVEDPDEPQNRMTK--YSILRGDYQDAFTIETNPAHNEGIIKPMKPL 325
Query: 443 DFEAKQQYILHVAVTNV---VPFEVSLTTSTATVTVDVLDVNEAPIFVPPEKRVEVSEDF 499
D+E QQY V T+ + + + A V +++ DV+E PIF P ++ E+
Sbjct: 326 DYEYIQQYSFIVEATDPTIDLRYMSPPAGNRAQVIINITDVDEPPIFQQPFYHFQLKEN- 384
Query: 500 GVGQEITSYTAQEPDTFMEQKITYRIWR--DTANWLEINPDTGAISTRAELDREDFEHVK 557
I + A +PD I Y I R D + + G I ELDRE +
Sbjct: 385 QKKPLIGTVLAMDPDA-ARHSIGYSIRRTSDKGQFFRVTKK-GDIYNEKELDREVYPWYN 442
Query: 558 NSTYTALIIATDNGSPVATGTGTLLLI---LSDVNDNAP-IPEPRTIFFCERNPKPQV-- 611
+ + +T G+P TG +++ + + D NDNAP +P CE Q+
Sbjct: 443 LTVEAKELDST--GTP--TGKESIVQVHIEVLDENDNAPEFAKPYQPKVCENAVHGQLVL 498
Query: 612 -INIIDADLPPNT----------SPFTAELTHGASANWTIQYNDPTQESIILKPKMALEV 660
I+ ID D+ P + FT H +AN T++Y +E +
Sbjct: 499 QISAIDKDITPRNVKFKFILNTENNFTLTDNHDNTANITVKYGQFDREHTKV-------- 550
Query: 661 GDYKINLKLMDN--QNKDQVTTLEVSVCDC--EGAAGVCRKAQPVEAGLQIPAILGILGG 716
+ + + + DN ++ +TL V+VC C +G C + G+ I A++ IL
Sbjct: 551 --HFLPVVISDNGMPSRTGTSTLTVAVCKCNEQGEFTFCED-MAAQVGVSIQAVVAIL-- 605
Query: 717 ILALLILILLLLLFLRRR----AVVKEPLLPPEDDTRDNVYYYDEEGGGEEDQ-DFDLSQ 771
+ L I ++ LL+FLRRR A +P + + + YDEEGGGE D +D+S
Sbjct: 606 LCILTITVITLLIFLRRRLRKQARAHGKSVP---EIHEQLVTYDEEGGGEMDTTSYDVSV 662
Query: 772 LH--RGLDARPEVTRNDVAPTLMSVPRYLPRPA-----NPDEIGNFIDENLKAADTDPTA 824
L+ R A+P D P+L + + PR A P E+ I+ AD D
Sbjct: 663 LNSVRRGGAKPPRPALDARPSLYAQVQKPPRHAPGAHGGPGEMAAMIEVKKDEADHDGDG 722
Query: 825 PPYDSLLVFDYEGSGSEAASLSSLNSSESDKDQDYDYLNEWGNRFKKLADMYG 877
PPYD+L ++ YEGS S A SLSSL + SD D DYD+LN+WG RFK LA++YG
Sbjct: 723 PPYDTLHIYGYEGSESIAESLSSLGTDSSDSDVDYDFLNDWGPRFKMLAELYG 775
>gi|16753221 cadherin 22 precursor [Homo sapiens]
Length = 828
Score = 303 bits (776), Expect = 5e-82
Identities = 261/796 (32%), Positives = 376/796 (47%), Gaps = 90/796 (11%)
Query: 148 GLRRQKRDWVIPPISCPENEKGPFPKNLVQIKSNKDK-EGKVFYSITGQGADTPPVGVFI 206
G R KR WV E G P + +I S+ D+ +G + Y+I+G+GA T +F+
Sbjct: 56 GAGRVKRGWVWNQFFVVEEYTGTEPLYVGKIHSDSDEGDGAIKYTISGEGAGT----IFL 111
Query: 207 IERETGWLKVTEPLDRERIATYTLFSHAVSSNGNAVEDP-MEILITVTDQNDNKPEFTQE 265
I+ TG + E LDRE+ YTL + A N + +P E +I V D ND++P F
Sbjct: 112 IDELTGDIHAMERLDREQKTFYTLRAQARDRATNRLLEPESEFIIKVQDINDSEPRFLHG 171
Query: 266 VFKGSVMEGALPGTSVMEVTATDADDDVNTYNAAIAYTILSQDPELPDKNMFTINRNTGV 325
+ GSV E + GTSVM+V A+DADD +A + Y++L ++ FT++ TGV
Sbjct: 172 PYIGSVAELSPTGTSVMQVMASDADDPTYGSSARLVYSVLD------GEHHFTVDPKTGV 225
Query: 326 ISVVTTGLDRESFPTYTLVVQAADLQGE--GLSTTATAVITVTDTNDNPPIFNPTTYKGQ 383
I LDRES Y +V+QA D+ G+ GLS + T I VTD NDNPP F Y+
Sbjct: 226 IRTAVPDLDRESQERYEVVIQATDMAGQLGGLSGSTTVTIVVTDVNDNPPRFPQKMYQFS 285
Query: 384 VPEN-EANVVITTLKVTDAD-APNTPAWEAVYTILNDDGGQFVVTTNPVNNDGILKTAKG 441
+ E+ + +K D+D NT + + G F VTT+ + I+ K
Sbjct: 286 IQESAPIGTAVGRVKAEDSDVGENTDMTYHLKDESSSGGDVFKVTTDSDTQEAIIVVQKR 345
Query: 442 LDFEAKQQYILHVAVTN--VVPFEVSLTT--STATVTVDVLDVNEAPIFVPPEKRVEVSE 497
LDFE++ + + + N V P L T A V V V DV+E P F PP +EV E
Sbjct: 346 LDFESQPVHTVILEALNKFVDPRFADLGTFRDQAIVRVAVTDVDEPPEFRPPSGLLEVQE 405
Query: 498 DFGVGQEITSYTAQEPDTFMEQKITYRIWR--DTANWLEINPDTGAISTRAELDREDFEH 555
D VG + TA++PD + + Y I R D +I+ DTGAI T LDRE
Sbjct: 406 DAQVGSLVGVVTARDPDA-ANRPVRYAIDRESDLDQIFDIDADTGAIVTGKGLDRET--- 461
Query: 556 VKNSTYTALIIATDNGSPVATGTGTLLLILSDVNDNAP-IPEPRTIFFCERNPKP----Q 610
T L + DN + ++ +L + + DVNDN P + P CE + KP Q
Sbjct: 462 AGWHNITVLAMEADNHAQLS--RASLRIRILDVNDNPPELATPYEAAVCE-DAKPGQLIQ 518
Query: 611 VINIIDADLPPNTSPFTAELTHGASAN-----WTIQYN-----------DPTQESIILKP 654
I+++D D P F L A +N IQ N + ++ + P
Sbjct: 519 TISVVDRDEPQGGHRFYFRLVPEAPSNPHFSLLDIQDNTAAVHTQHVGFNRQEQDVFFLP 578
Query: 655 KMALEVGDYKINLKLMDNQNKDQVTTLEVSVCDCEGAAGVCRKAQPVEAGLQIPAILGIL 714
+ ++ G + + T+ + CD G C V A P L L
Sbjct: 579 ILVVDSGPPTL--------SSTGTLTIRICGCDSSGTIQSCNTTAFVMAASLSPGALIAL 630
Query: 715 GGILALLILILLLLLFLRRRAVVKEPLLPPED-DTRDNVYYYDEEGGGEEDQD-FDLSQL 772
++ +LIL++L+LL L R K L ED D RDNV Y++EGGGE+D + +D+S L
Sbjct: 631 --LVCVLILVVLVLLILTLRRHHKSHLSSDEDEDMRDNVIKYNDEGGGEQDTEAYDMSAL 688
Query: 773 HRGLDARPEVTRND------------------------VAPTLMSVPRYLPRPANPD--E 806
R L E+ D + S+P+ P P PD
Sbjct: 689 -RSLYDFGELKGGDGGGSAGGGAGGGSGGGAGSPPQAHLPSERHSLPQGPPSP-EPDFSV 746
Query: 807 IGNFIDENLKAADTDPTAPPYDSLLVFDYEGSGSEAASLSSLNSSESDKDQDYDYLNEWG 866
+FI + AD D + PPYD+ + +EG+ S AASLSSL+S S +QD+ YL+ WG
Sbjct: 747 FRDFISRKVALADGDLSVPPYDAFQTYAFEGADSPAASLSSLHSGSSGSEQDFAYLSSWG 806
Query: 867 NRFKKLADMYGGGEDD 882
RF+ LA +Y G D
Sbjct: 807 PRFRPLAALYAGHRGD 822
>gi|29789445 desmoglein 4 isoform 2 [Homo sapiens]
Length = 1040
Score = 295 bits (756), Expect = 1e-79
Identities = 244/820 (29%), Positives = 378/820 (46%), Gaps = 110/820 (13%)
Query: 149 LRRQKRDWVIPPISCPENEKGPFPKNLVQIKSNKDKEGKVFYSITGQGADTPPVGVFIIE 208
+RRQKR+W+ +C E E + +I+S+ + K+ Y I+G G D PP GVF I
Sbjct: 44 VRRQKREWIKFAAACREGEDNSKRNPIAKIRSDCESNQKITYRISGVGIDRPPYGVFTIN 103
Query: 209 RETGWLKVTEPLDRERIATYTLFSHAVSSNGNAVEDPMEILITVTDQNDNKPEFTQEVFK 268
TG + +T +DRE + ++ A++S G +E P+E+ + V D NDN P F+Q V+
Sbjct: 104 PRTGEINITSVVDREITPLFLIYCRALNSRGEDLERPLELRVKVMDINDNAPVFSQSVYT 163
Query: 269 GSVMEGALPGTSVMEVTATDADDDVNTYNAAIAYTILSQDPELPDKNMFTINRNTGVISV 328
S+ E + T V+++ ATDAD++ N N+ IAY I+SQ+P MF +NR TG +
Sbjct: 164 ASIEENSDANTLVVKLCATDADEE-NHLNSKIAYKIVSQEPS--GAPMFILNRYTGEVCT 220
Query: 329 VTTGLDRESFPTYTLVVQAADLQG--EGLSTTATAVITVTDTNDNPPIFNPTTYKGQVPE 386
+++ LDRE Y LVV+ +D G +GLS+ I V D NDN P T+Y + E
Sbjct: 221 MSSFLDREQHSMYNLVVRGSDRDGAADGLSSECDCRIKVLDVNDNFPTLEKTSYSASIEE 280
Query: 387 NEANVVITTLKVTDADAPNTPAWEAVYTILN-DDGGQFVVTTNPVNNDGILKTAKGLDFE 445
N + + L+ D D T W A Y IL+ +DG F + T+P N+GILK K LD+E
Sbjct: 281 NCLSSELIRLQAIDLDEEGTDNWLAQYLILSGNDGNWFDIQTDPQTNEGILKVVKMLDYE 340
Query: 446 AKQQYILHVAVTNVVPFEVSLTTS----TATVTVDVLDVNEAPIFVPPEKRVEVSEDFG- 500
L + V N F S+ + V + V+DV E P F P V E
Sbjct: 341 QAPNIQLSIGVKNQADFHYSVASQFQMHPTPVRIQVVDVREGPAFHPSTMAFSVREGIKG 400
Query: 501 ---VGQEITSYTAQEPDT-FMEQKITYRIWRDTANWLEINPDTGAISTRAELDREDFEHV 556
+ + +YTA + DT + Y I D +WL+I+ TG I E D++ +++
Sbjct: 401 SSLLNYVLGTYTAIDLDTGNPATDVRYIIGHDAGSWLKIDSRTGEIQFSREFDKKS-KYI 459
Query: 557 KNSTYTALIIATDNGSPVATGTGTLLLILSDVNDNAP--IPEPRTIFFCERNPKPQVINI 614
N YTA I+A D+GS T TGT+ + + D+ND P PE RTI C +P +
Sbjct: 460 INGIYTAEILAIDDGSG-KTATGTICIEVPDINDYCPNIFPERRTI--CIDSPSV----L 512
Query: 615 IDADLPPNTSPFT---AELTHGASANWTIQYNDPTQESIILKPKMALEVGDYKINLKLMD 671
I + SPFT + G + W ++ + T S IL K L G Y+I + + D
Sbjct: 513 ISVNEHSYGSPFTFCVVDEPPGIADMWDVRSTNAT--SAILTAKQVLSPGFYEIPILVKD 570
Query: 672 NQNK--DQVTTLEVSVCDCE--------GAAGVCRK------AQPV---EAGLQI----P 708
+ N+ + +++ CDC+ GAAG+ + PV +AG+ P
Sbjct: 571 SYNRACELAQMVQLYACDCDDNHMCLDSGAAGIYTEDITGDTYGPVTEDQAGVSNVGLGP 630
Query: 709 AILGILGGILALLILILLLLLFLRRRAVVKEP------LLPPEDDTRDNVYYYDEEGGGE 762
A +G++ +L +L+LIL LL L ++P P + + + EG
Sbjct: 631 AGIGMM--VLGILLLILAPLLLLLCCCKQRQPEGLGTRFAPVPEGGEGVMQSWRIEGAHP 688
Query: 763 EDQD----------------FDLSQLHRGLDARPEVTRNDV------------------- 787
ED+D D S+++ A V
Sbjct: 689 EDRDVSNICAPMTASNTQDRMDSSEIYTNTYAAGGTVEGGVSGVELNTGMGTAVGLMAAG 748
Query: 788 -----------APTLMSVPRYLPRPANPDEIGNFIDENLKA-ADTDPTAPPYDSLLVFDY 835
+ T+ ++ Y N + ++ E A AD D P D LL++D+
Sbjct: 749 AAGASGAARKRSSTMGTLRDYADADINMAFLDSYFSEKAYAYADEDEGRPANDCLLIYDH 808
Query: 836 EGSGSEAASLSSLNSSESDKDQDYDYLNEWGNRFKKLADM 875
EG GS S+ + D D+ + +F+ LA++
Sbjct: 809 EGVGSPVGSIGCCSWIVDDLDE--SCMETLDPKFRTLAEI 846
>gi|116534898 desmoglein 2 preproprotein [Homo sapiens]
Length = 1118
Score = 294 bits (752), Expect = 3e-79
Identities = 217/661 (32%), Positives = 329/661 (49%), Gaps = 43/661 (6%)
Query: 133 SGIQAELLTFPNSS------PGLRRQKRDWVIPPISCPENEKGPFPKNLVQIKSNKDKEG 186
SG+ ++L+ N + P L RQKR W+ P++ E E + +I S+ +E
Sbjct: 22 SGLHLQVLSTRNENKLLPKHPHLVRQKRAWITAPVALREGEDLSKKNPIAKIHSDLAEER 81
Query: 187 --KVFYSITGQGADTPPVGVFIIERETGWLKVTEPLDRERIATYTLFSHAVSSNGNAVED 244
K+ Y TG+G PP G+F+ ++TG L VT LDRE + L +A+ + GN VE
Sbjct: 82 GLKITYKYTGKGITEPPFGIFVFNKDTGELNVTSILDREETPFFLLTGYALDARGNNVEK 141
Query: 245 PMEILITVTDQNDNKPEFTQEVFKGSVMEGALPGTSVMEVTATDADDDVNTYNAAIAYTI 304
P+E+ I V D NDN+P FTQ+VF GSV E + T VM++ ATDAD+ NT N+ I+Y I
Sbjct: 142 PLELRIKVLDINDNEPVFTQDVFVGSVEELSAAHTLVMKINATDADEP-NTLNSKISYRI 200
Query: 305 LSQDPELPDKNMFTINRNTGVISVVTTGLDRESFPTYTLVVQAADLQGEGLS---TTATA 361
+S +P P +F +N++TG I + LDRE +YTL V+A D GE A
Sbjct: 201 VSLEPAYPP--VFYLNKDTGEIYTTSVTLDREEHSSYTLTVEARDGNGEVTDKPVKQAQV 258
Query: 362 VITVTDTNDNPPIFNPTTYKGQVPENEANVVITTLKVTDADAPNTPAWEAVYTILN-DDG 420
I + D NDN P+ +G V EN+ NV +T +KV DAD + W A +T + ++G
Sbjct: 259 QIRILDVNDNIPVVENKVLEGMVEENQVNVEVTRIKVFDADEIGSDNWLANFTFASGNEG 318
Query: 421 GQFVVTTNPVNNDGILKTAKGLDFEAKQQYILHVAVTNVVPFEVSLTT----STATVTVD 476
G F + T+ N+GI+ K +D+E + V V N F S+ + + + V
Sbjct: 319 GYFHIETDAQTNEGIVTLIKEVDYEEMKNLDFSVIVANKAAFHKSIRSKYKPTPIPIKVK 378
Query: 477 VLDVNEAPIFVPPEKRVEVSEDF---GVGQEITSYTAQEPDTFMEQKITYRIWRDTANWL 533
V +V E F + VSE GQ I ++ A + DT + Y D NW+
Sbjct: 379 VKNVKEGIHFKSSVISIYVSESMDRSSKGQIIGNFQAFDEDTGLPAHARYVKLEDRDNWI 438
Query: 534 EINPDTGAISTRAELDREDFEHVKNSTYTALIIATDNGSPVATGTGTLLLILSDVNDNAP 593
++ T I A+L + +V+N TYT I+A P T TGT+L+ + D+NDN P
Sbjct: 439 SVDSVTSEIKL-AKLPDFESRYVQNGTYTVKIVAISEDYPRKTITGTVLINVEDINDNCP 497
Query: 594 IPEPRTIFFCERNPKPQVINIIDADLP--PNTSPFTAELTH---GASANWTIQYNDPTQE 648
C + +N+ DL PN+ PF+ + G + W I + T
Sbjct: 498 TLIEPVQTICH---DAEYVNVTAEDLDGHPNSGPFSFSVIDKPPGMAEKWKIARQESTS- 553
Query: 649 SIILKPKMALEVGDYKINLKLMDNQN----KDQVTTLEVSVCDCEGAAGVCRKAQPVEAG 704
+L + ++G +I + DNQ + QV TL +VC+C +G CR+AQ
Sbjct: 554 --VLLQQSEKKLGRSEIQFLISDNQGFSCPEKQVLTL--TVCECLHGSG-CREAQHDSYV 608
Query: 705 LQIPAILGILGGILALLILILLLLLFLRRRAVVKEPLLPPEDDTRDNVYYYDEEGGGEED 764
PA + ++ ILA L+L+L+ LL L P T + ++ ++ EG ED
Sbjct: 609 GLGPAAIALM--ILAFLLLLLVPLLLLMCHCGKGAKGFTPIPGTIEMLHPWNNEGAPPED 666
Query: 765 Q 765
+
Sbjct: 667 K 667
Database: hs.faa
Posted date: Aug 4, 2009 4:42 PM
Number of letters in database: 18,247,518
Number of sequences in database: 37,866
Lambda K H
0.315 0.134 0.396
Gapped
Lambda K H
0.267 0.0410 0.140
Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Hits to DB: 36,357,507
Number of Sequences: 37866
Number of extensions: 1764888
Number of successful extensions: 7681
Number of sequences better than 10.0: 30
Number of HSP's better than 10.0 without gapping: 205
Number of HSP's successfully gapped in prelim test: 33
Number of HSP's that attempted gapping in prelim test: 3562
Number of HSP's gapped (non-prelim): 972
length of query: 882
length of database: 18,247,518
effective HSP length: 111
effective length of query: 771
effective length of database: 14,044,392
effective search space: 10828226232
effective search space used: 10828226232
T: 11
A: 40
X1: 16 ( 7.3 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 42 (22.0 bits)
S2: 66 (30.0 bits)
Search results were obtained with NCBI BLAST and RefSeq entries.
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Guide to the Human Genome
Copyright © 2010 by Stewart Scherer. All rights reserved.