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Search of human proteins with 4757934
BLASTP 2.2.11 [Jun-05-2005]
Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer,
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997),
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs", Nucleic Acids Res. 25:3389-3402.
Query= gi|4757934 cyclin G1 [Homo sapiens]
(295 letters)
Database: hs.faa
37,866 sequences; 18,247,518 total letters
Searching..................................................done
Score E
Sequences producing significant alignments: (bits) Value
gi|40805832 cyclin G1 [Homo sapiens] 588 e-168
gi|4757934 cyclin G1 [Homo sapiens] 588 e-168
gi|4757936 cyclin G2 [Homo sapiens] 295 3e-80
gi|5802992 cyclin I [Homo sapiens] 106 2e-23
gi|89886237 cyclin I family, member 2 [Homo sapiens] 84 1e-16
gi|16950655 cyclin D1 [Homo sapiens] 65 5e-11
gi|4502613 cyclin A [Homo sapiens] 63 4e-10
gi|161377472 cyclin A1 isoform c [Homo sapiens] 55 1e-07
gi|161377470 cyclin A1 isoform c [Homo sapiens] 55 1e-07
gi|161377468 cyclin A1 isoform b [Homo sapiens] 55 1e-07
gi|4502611 cyclin A1 isoform a [Homo sapiens] 55 1e-07
gi|4502617 cyclin D2 [Homo sapiens] 54 1e-07
gi|4502619 cyclin D3 isoform 2 [Homo sapiens] 52 5e-07
gi|90669307 cyclin B3 isoform 3 [Homo sapiens] 52 6e-07
gi|16306525 cyclin B3 isoform 1 [Homo sapiens] 50 2e-06
gi|242247025 cyclin N-terminal domain containing 2 isoform 2 [Ho... 49 5e-06
gi|197276676 cyclin J isoform 3 [Homo sapiens] 49 5e-06
gi|197276674 cyclin J isoform 1 [Homo sapiens] 49 5e-06
gi|40254889 cyclin J isoform 2 [Homo sapiens] 49 5e-06
gi|4757930 cyclin B2 [Homo sapiens] 48 9e-06
gi|153791755 cyclin domain containing [Homo sapiens] 48 1e-05
gi|17318565 cyclin E2 [Homo sapiens] 47 3e-05
gi|209862835 cyclin D3 isoform 1 [Homo sapiens] 44 2e-04
gi|14327896 cyclin B1 [Homo sapiens] 40 0.003
gi|17318559 cyclin E1 isoform 1 [Homo sapiens] 39 0.007
gi|17318561 cyclin E1 isoform 2 [Homo sapiens] 39 0.007
gi|118572588 cyclin F [Homo sapiens] 34 0.18
gi|22538387 A-kinase anchor protein 9 isoform 2 [Homo sapiens] 33 0.30
gi|22538393 A-kinase anchor protein 9 isoform 3 [Homo sapiens] 33 0.30
gi|76257392 ubiquitin specific protease 48 isoform b [Homo sapiens] 30 1.9
>gi|40805832 cyclin G1 [Homo sapiens]
Length = 295
Score = 588 bits (1515), Expect = e-168
Identities = 295/295 (100%), Positives = 295/295 (100%)
Query: 1 MIEVLTTTDSQKLLHQLNALLEQESRCQPKVCGLRLIESAHDNGLRMTARLRDFEVKDLL 60
MIEVLTTTDSQKLLHQLNALLEQESRCQPKVCGLRLIESAHDNGLRMTARLRDFEVKDLL
Sbjct: 1 MIEVLTTTDSQKLLHQLNALLEQESRCQPKVCGLRLIESAHDNGLRMTARLRDFEVKDLL 60
Query: 61 SLTQFFGFDTETFSLAVNLLDRFLSKMKVQPKHLGCVGLSCFYLAVKSIEEERNVPLATD 120
SLTQFFGFDTETFSLAVNLLDRFLSKMKVQPKHLGCVGLSCFYLAVKSIEEERNVPLATD
Sbjct: 61 SLTQFFGFDTETFSLAVNLLDRFLSKMKVQPKHLGCVGLSCFYLAVKSIEEERNVPLATD 120
Query: 121 LIRISQYRFTVSDLMRMEKIVLEKVCWKVKATTAFQFLQLYYSLLQENLPLERRNSINFE 180
LIRISQYRFTVSDLMRMEKIVLEKVCWKVKATTAFQFLQLYYSLLQENLPLERRNSINFE
Sbjct: 121 LIRISQYRFTVSDLMRMEKIVLEKVCWKVKATTAFQFLQLYYSLLQENLPLERRNSINFE 180
Query: 181 RLEAQLKACHCRIIFSKAKPSVLALSIIALEIQAQKCVELTEGIECLQKHSKINGRDLTF 240
RLEAQLKACHCRIIFSKAKPSVLALSIIALEIQAQKCVELTEGIECLQKHSKINGRDLTF
Sbjct: 181 RLEAQLKACHCRIIFSKAKPSVLALSIIALEIQAQKCVELTEGIECLQKHSKINGRDLTF 240
Query: 241 WQELVSKCLTEYSSNKCSKPNVQKLKWIVSGRTARQLKHSYYRITHLPTIPEMVP 295
WQELVSKCLTEYSSNKCSKPNVQKLKWIVSGRTARQLKHSYYRITHLPTIPEMVP
Sbjct: 241 WQELVSKCLTEYSSNKCSKPNVQKLKWIVSGRTARQLKHSYYRITHLPTIPEMVP 295
>gi|4757934 cyclin G1 [Homo sapiens]
Length = 295
Score = 588 bits (1515), Expect = e-168
Identities = 295/295 (100%), Positives = 295/295 (100%)
Query: 1 MIEVLTTTDSQKLLHQLNALLEQESRCQPKVCGLRLIESAHDNGLRMTARLRDFEVKDLL 60
MIEVLTTTDSQKLLHQLNALLEQESRCQPKVCGLRLIESAHDNGLRMTARLRDFEVKDLL
Sbjct: 1 MIEVLTTTDSQKLLHQLNALLEQESRCQPKVCGLRLIESAHDNGLRMTARLRDFEVKDLL 60
Query: 61 SLTQFFGFDTETFSLAVNLLDRFLSKMKVQPKHLGCVGLSCFYLAVKSIEEERNVPLATD 120
SLTQFFGFDTETFSLAVNLLDRFLSKMKVQPKHLGCVGLSCFYLAVKSIEEERNVPLATD
Sbjct: 61 SLTQFFGFDTETFSLAVNLLDRFLSKMKVQPKHLGCVGLSCFYLAVKSIEEERNVPLATD 120
Query: 121 LIRISQYRFTVSDLMRMEKIVLEKVCWKVKATTAFQFLQLYYSLLQENLPLERRNSINFE 180
LIRISQYRFTVSDLMRMEKIVLEKVCWKVKATTAFQFLQLYYSLLQENLPLERRNSINFE
Sbjct: 121 LIRISQYRFTVSDLMRMEKIVLEKVCWKVKATTAFQFLQLYYSLLQENLPLERRNSINFE 180
Query: 181 RLEAQLKACHCRIIFSKAKPSVLALSIIALEIQAQKCVELTEGIECLQKHSKINGRDLTF 240
RLEAQLKACHCRIIFSKAKPSVLALSIIALEIQAQKCVELTEGIECLQKHSKINGRDLTF
Sbjct: 181 RLEAQLKACHCRIIFSKAKPSVLALSIIALEIQAQKCVELTEGIECLQKHSKINGRDLTF 240
Query: 241 WQELVSKCLTEYSSNKCSKPNVQKLKWIVSGRTARQLKHSYYRITHLPTIPEMVP 295
WQELVSKCLTEYSSNKCSKPNVQKLKWIVSGRTARQLKHSYYRITHLPTIPEMVP
Sbjct: 241 WQELVSKCLTEYSSNKCSKPNVQKLKWIVSGRTARQLKHSYYRITHLPTIPEMVP 295
>gi|4757936 cyclin G2 [Homo sapiens]
Length = 344
Score = 295 bits (755), Expect = 3e-80
Identities = 153/290 (52%), Positives = 209/290 (72%), Gaps = 1/290 (0%)
Query: 3 EVLTTTDSQKLLHQLNALLEQESRCQPKVCGLRLIESAHDNGLRMTARLRDFEVKDLLSL 62
E L + +LL LN LEQE R QP+ GL LIE+ +N + LR+ +V+DL SL
Sbjct: 7 EHLAGHEGVQLLGLLNVYLEQEERFQPREKGLSLIEATPENDNTLCPGLRNAKVEDLRSL 66
Query: 63 TQFFGFDTETFSLAVNLLDRFLSKMKVQPKHLGCVGLSCFYLAVKSIEEERNVPLATDLI 122
FFG TETF LAVN+LDRFL+ MKV+PKHL C+G+ F LA + +EE+ N+P D+I
Sbjct: 67 ANFFGSCTETFVLAVNILDRFLALMKVKPKHLSCIGVCSFLLAARIVEEDCNIPSTHDVI 126
Query: 123 RISQYRFTVSDLMRMEKIVLEKVCWKVKATTAFQFLQLYYSLLQENLPLERRNSINFERL 182
RISQ + T SD+ RMEKI+ EK+ ++++ATTA FL LY++++ + ER+ ++ ++L
Sbjct: 127 RISQCKCTASDIKRMEKIISEKLHYELEATTALNFLHLYHTIILCHTS-ERKEILSLDKL 185
Query: 183 EAQLKACHCRIIFSKAKPSVLALSIIALEIQAQKCVELTEGIECLQKHSKINGRDLTFWQ 242
EAQLKAC+CR+IFSKAKPSVLAL ++ LE++ K VEL E + ++KHSKIN + +W+
Sbjct: 186 EAQLKACNCRLIFSKAKPSVLALCLLNLEVETLKSVELLEILLLVKKHSKINDTEFFYWR 245
Query: 243 ELVSKCLTEYSSNKCSKPNVQKLKWIVSGRTARQLKHSYYRITHLPTIPE 292
ELVSKCL EYSS +C KP+++KL WIVS RTA+ L +SYY + LPTIPE
Sbjct: 246 ELVSKCLAEYSSPECCKPDLKKLVWIVSRRTAQNLHNSYYSVPELPTIPE 295
>gi|5802992 cyclin I [Homo sapiens]
Length = 377
Score = 106 bits (265), Expect = 2e-23
Identities = 68/210 (32%), Positives = 117/210 (55%), Gaps = 7/210 (3%)
Query: 52 RDFEVKDLLSLTQFFGFDTETFSLAVNLLDRFLSKMKVQPKHLGCVGLSCFYLAVKSIEE 111
RD ++ L L F ETF+LA +LLDRFL+ +K PK+L C+ +SCF+LA K++EE
Sbjct: 45 RDEVIQWLAKLKYQFNLYPETFALASSLLDRFLATVKAHPKYLSCIAISCFFLAAKTVEE 104
Query: 112 ERNVPLATDLIRISQYRFTVSDLMRMEKIVLEKVCWKVKATTAFQFLQLYYSLLQENLPL 171
+ +P+ L R S + S+++RME+I+L+K+ W + T FL +++++ P
Sbjct: 105 DERIPVLKVLARDSFCGCSSSEILRMERIILDKLNWDLHTATPLDFLHIFHAIAVSTRPQ 164
Query: 172 ------ERRNSINFERLEAQLKACHCRIIFSKAKPSVLALSIIALEIQAQKCVELTEGIE 225
+ S + L QL C + + S+LAL++++LE++ L+ IE
Sbjct: 165 LLFSLPKLSPSQHLAVLTKQLLHCMACNQLLQFRGSMLALAMVSLEMEKLIPDWLSLTIE 224
Query: 226 CLQKHSKINGRDLTFWQELVSKCLTEYSSN 255
LQK ++++ L +ELV+ L+ S+
Sbjct: 225 LLQK-AQMDSSQLIHCRELVAHHLSTLQSS 253
>gi|89886237 cyclin I family, member 2 [Homo sapiens]
Length = 369
Score = 84.3 bits (207), Expect = 1e-16
Identities = 61/209 (29%), Positives = 105/209 (50%), Gaps = 13/209 (6%)
Query: 59 LLSLTQFFGFDTETFSLAVNLLDRFLSKMKVQPKHLGCVGLSCFYLAVKSIEEERNVPLA 118
LL L F F TF+LA+ + R L +KV+ K+L C ++ LA K EEE +P
Sbjct: 157 LLRLQNTFYFSQSTFNLALTIFGRLLISVKVKEKYLHCATITSLRLAAKVNEEEEFIPQV 216
Query: 119 TDLIRISQYRFTVSDLMRMEKIVLEKVCWKVKATTAFQFLQLYYSLLQENLP-----LER 173
D + ++ ++L+RME +L+++ W + T FL ++++L+ + P L +
Sbjct: 217 KDFTKHYGSDYSPNELLRMELAILDRLHWDLYIGTPLDFLTIFHALVVLSWPHVLELLPQ 276
Query: 174 RN-SINFERLEAQLKACHCRIIFSKAKPSVLALSIIALEIQAQK---CVELTEGIECLQK 229
RN S++ L QL+ C + K S LAL II LE++ C +++ L K
Sbjct: 277 RNPSLHVASLTRQLQHCMAGHQLLQFKGSTLALVIITLELERLMPGWCAPISD----LLK 332
Query: 230 HSKINGRDLTFWQELVSKCLTEYSSNKCS 258
+++ + +ELV + L S+ C+
Sbjct: 333 KAQVGDMQYSCCKELVMQQLRSLQSSSCT 361
>gi|16950655 cyclin D1 [Homo sapiens]
Length = 295
Score = 65.5 bits (158), Expect = 5e-11
Identities = 50/201 (24%), Positives = 93/201 (46%), Gaps = 19/201 (9%)
Query: 17 LNALLEQESRCQPKVCGLRLIESAHDNGLRMTARLRDFEVKDLLSLTQFFGFDTETFSLA 76
L A+L+ E C P V + ++ + +R +L + + + E F LA
Sbjct: 28 LRAMLKAEETCAPSVSYFKCVQK------EVLPSMRKIVATWMLEVCEEQKCEEEVFPLA 81
Query: 77 VNLLDRFLSKMKVQPKHLGCVGLSCFYLAVKSIEEERNVPLATDLIRI-SQYRFTVSDLM 135
+N LDRFLS V+ L +G +C ++A K E +PL + + I + +L+
Sbjct: 82 MNYLDRFLSLEPVKKSRLQLLGATCMFVASKMKE---TIPLTAEKLCIYTDNSIRPEELL 138
Query: 136 RMEKIVLEKVCWKVKATTAFQFLQLYYSLL---QENLPLERRNSINFERLEAQLKACHCR 192
+ME +++ K+ W + A T F++ + S + +EN + R+++ F L C
Sbjct: 139 QMELLLVNKLKWNLAAMTPHDFIEHFLSKMPEAEENKQIIRKHAQTFVAL------CATD 192
Query: 193 IIFSKAKPSVLALSIIALEIQ 213
+ F PS++A + +Q
Sbjct: 193 VKFISNPPSMVAAGSVVAAVQ 213
>gi|4502613 cyclin A [Homo sapiens]
Length = 432
Score = 62.8 bits (151), Expect = 4e-10
Identities = 46/143 (32%), Positives = 70/143 (48%), Gaps = 9/143 (6%)
Query: 20 LLEQESRCQPKVCGLRLIESAHDNGLRMTARLRDFEVKDLLSLTQFFGFDTETFSLAVNL 79
L E E +C+PKV ++ +T +R V L+ + + + ET LAVN
Sbjct: 186 LREMEVKCKPKVGYMKKQPD-------ITNSMRAILVDWLVEVGEEYKLQNETLHLAVNY 238
Query: 80 LDRFLSKMKVQPKHLGCVGLSCFYLAVKSIEEERNVPLATDLIRISQYRFTVSDLMRMEK 139
+DRFLS M V L VG + LA K EE P + + I+ +T ++RME
Sbjct: 239 IDRFLSSMSVLRGKLQLVGTAAMLLASKF--EEIYPPEVAEFVYITDDTYTKKQVLRMEH 296
Query: 140 IVLEKVCWKVKATTAFQFLQLYY 162
+VL+ + + + A T QFL Y+
Sbjct: 297 LVLKVLTFDLAAPTVNQFLTQYF 319
>gi|161377472 cyclin A1 isoform c [Homo sapiens]
Length = 421
Score = 54.7 bits (130), Expect = 1e-07
Identities = 58/208 (27%), Positives = 96/208 (46%), Gaps = 17/208 (8%)
Query: 3 EVLTTTDSQKLLHQLNALLEQESRCQPKVCGLRLIESAHDNGLRMTARLRDFEVKDLLSL 62
+V+ T+ + ++Q L E E R +PK ++ D +T +R V L+ +
Sbjct: 160 DVINVTEYAEEIYQY--LREAEIRHRPKA---HYMKKQPD----ITEGMRTILVDWLVEV 210
Query: 63 TQFFGFDTETFSLAVNLLDRFLSKMKVQPKHLGCVGLSCFYLAVKSIEEERNVPLATDLI 122
+ + ET LAVN LDRFLS M V L VG + LA K EE P + +
Sbjct: 211 GEEYKLRAETLYLAVNFLDRFLSCMSVLRGKLQLVGTAAMLLASK--YEEIYPPEVDEFV 268
Query: 123 RISQYRFTVSDLMRMEKIVLEKVCWKVKATTAFQFLQLYYSLLQENLPLERRNSINFERL 182
I+ +T L++ME ++L+ + + + T QFL Y L ++ + + N +
Sbjct: 269 YITDDTYTKRQLLKMEHLLLKVLAFDLTVPTTNQFLLQY--LRRQGVCVRTENLAKYVAE 326
Query: 183 EAQLKACHCRIIFSKAKPSVLALSIIAL 210
+ L+A F K PS++A + L
Sbjct: 327 LSLLEADP----FLKYLPSLIAAAAFCL 350
>gi|161377470 cyclin A1 isoform c [Homo sapiens]
Length = 421
Score = 54.7 bits (130), Expect = 1e-07
Identities = 58/208 (27%), Positives = 96/208 (46%), Gaps = 17/208 (8%)
Query: 3 EVLTTTDSQKLLHQLNALLEQESRCQPKVCGLRLIESAHDNGLRMTARLRDFEVKDLLSL 62
+V+ T+ + ++Q L E E R +PK ++ D +T +R V L+ +
Sbjct: 160 DVINVTEYAEEIYQY--LREAEIRHRPKA---HYMKKQPD----ITEGMRTILVDWLVEV 210
Query: 63 TQFFGFDTETFSLAVNLLDRFLSKMKVQPKHLGCVGLSCFYLAVKSIEEERNVPLATDLI 122
+ + ET LAVN LDRFLS M V L VG + LA K EE P + +
Sbjct: 211 GEEYKLRAETLYLAVNFLDRFLSCMSVLRGKLQLVGTAAMLLASK--YEEIYPPEVDEFV 268
Query: 123 RISQYRFTVSDLMRMEKIVLEKVCWKVKATTAFQFLQLYYSLLQENLPLERRNSINFERL 182
I+ +T L++ME ++L+ + + + T QFL Y L ++ + + N +
Sbjct: 269 YITDDTYTKRQLLKMEHLLLKVLAFDLTVPTTNQFLLQY--LRRQGVCVRTENLAKYVAE 326
Query: 183 EAQLKACHCRIIFSKAKPSVLALSIIAL 210
+ L+A F K PS++A + L
Sbjct: 327 LSLLEADP----FLKYLPSLIAAAAFCL 350
>gi|161377468 cyclin A1 isoform b [Homo sapiens]
Length = 464
Score = 54.7 bits (130), Expect = 1e-07
Identities = 58/208 (27%), Positives = 96/208 (46%), Gaps = 17/208 (8%)
Query: 3 EVLTTTDSQKLLHQLNALLEQESRCQPKVCGLRLIESAHDNGLRMTARLRDFEVKDLLSL 62
+V+ T+ + ++Q L E E R +PK ++ D +T +R V L+ +
Sbjct: 203 DVINVTEYAEEIYQY--LREAEIRHRPKA---HYMKKQPD----ITEGMRTILVDWLVEV 253
Query: 63 TQFFGFDTETFSLAVNLLDRFLSKMKVQPKHLGCVGLSCFYLAVKSIEEERNVPLATDLI 122
+ + ET LAVN LDRFLS M V L VG + LA K EE P + +
Sbjct: 254 GEEYKLRAETLYLAVNFLDRFLSCMSVLRGKLQLVGTAAMLLASK--YEEIYPPEVDEFV 311
Query: 123 RISQYRFTVSDLMRMEKIVLEKVCWKVKATTAFQFLQLYYSLLQENLPLERRNSINFERL 182
I+ +T L++ME ++L+ + + + T QFL Y L ++ + + N +
Sbjct: 312 YITDDTYTKRQLLKMEHLLLKVLAFDLTVPTTNQFLLQY--LRRQGVCVRTENLAKYVAE 369
Query: 183 EAQLKACHCRIIFSKAKPSVLALSIIAL 210
+ L+A F K PS++A + L
Sbjct: 370 LSLLEADP----FLKYLPSLIAAAAFCL 393
>gi|4502611 cyclin A1 isoform a [Homo sapiens]
Length = 465
Score = 54.7 bits (130), Expect = 1e-07
Identities = 58/208 (27%), Positives = 96/208 (46%), Gaps = 17/208 (8%)
Query: 3 EVLTTTDSQKLLHQLNALLEQESRCQPKVCGLRLIESAHDNGLRMTARLRDFEVKDLLSL 62
+V+ T+ + ++Q L E E R +PK ++ D +T +R V L+ +
Sbjct: 204 DVINVTEYAEEIYQY--LREAEIRHRPKA---HYMKKQPD----ITEGMRTILVDWLVEV 254
Query: 63 TQFFGFDTETFSLAVNLLDRFLSKMKVQPKHLGCVGLSCFYLAVKSIEEERNVPLATDLI 122
+ + ET LAVN LDRFLS M V L VG + LA K EE P + +
Sbjct: 255 GEEYKLRAETLYLAVNFLDRFLSCMSVLRGKLQLVGTAAMLLASK--YEEIYPPEVDEFV 312
Query: 123 RISQYRFTVSDLMRMEKIVLEKVCWKVKATTAFQFLQLYYSLLQENLPLERRNSINFERL 182
I+ +T L++ME ++L+ + + + T QFL Y L ++ + + N +
Sbjct: 313 YITDDTYTKRQLLKMEHLLLKVLAFDLTVPTTNQFLLQY--LRRQGVCVRTENLAKYVAE 370
Query: 183 EAQLKACHCRIIFSKAKPSVLALSIIAL 210
+ L+A F K PS++A + L
Sbjct: 371 LSLLEADP----FLKYLPSLIAAAAFCL 394
>gi|4502617 cyclin D2 [Homo sapiens]
Length = 289
Score = 54.3 bits (129), Expect = 1e-07
Identities = 46/166 (27%), Positives = 74/166 (44%), Gaps = 20/166 (12%)
Query: 69 DTETFSLAVNLLDRFLSKMKVQPKHLGCVGLSCFYLAVKSIEEERNVPLATDLIRI-SQY 127
+ E F LA+N LDRFL+ + HL +G C +LA K E PL + + I +
Sbjct: 73 EEEVFPLAMNYLDRFLAGVPTPKSHLQLLGAVCMFLASKLKETS---PLTAEKLCIYTDN 129
Query: 128 RFTVSDLMRMEKIVLEKVCWKVKATTAFQFLQLYYSLLQENLPLERRNSINFERLEAQ-- 185
+L+ E +VL K+ W + A T F++ + LP ++R ++ R AQ
Sbjct: 130 SIKPQELLEWELVVLGKLKWNLAAVTPHDFIE----HILRKLP-QQREKLSLIRKHAQTF 184
Query: 186 LKACHCRIIFSKAKPSVLALSIIAL---------EIQAQKCVELTE 222
+ C F+ PS++A + E+ + C LTE
Sbjct: 185 IALCATDFKFAMYPPSMIATGSVGAAICGLQQDEEVSSLTCDALTE 230
>gi|4502619 cyclin D3 isoform 2 [Homo sapiens]
Length = 292
Score = 52.4 bits (124), Expect = 5e-07
Identities = 59/239 (24%), Positives = 101/239 (42%), Gaps = 17/239 (7%)
Query: 17 LNALLEQESRCQPKVCGLRLIESAHDNGLRMTARLRDFEVKDLLSLTQFFGFDTETFSLA 76
L +LL E R P+ + ++ + +R +L + + + E F LA
Sbjct: 28 LQSLLRLEERYVPRASYFQCVQR------EIKPHMRKMLAYWMLEVCEEQRCEEEVFPLA 81
Query: 77 VNLLDRFLSKMKVQPKHLGCVGLSCFYLAVKSIEEERNVPLATDLIRI-SQYRFTVSDLM 135
+N LDR+LS + + L +G C LA K E PL + + I + + + L
Sbjct: 82 MNYLDRYLSCVPTRKAQLQLLGAVCMLLASKLRE---TTPLTIEKLCIYTDHAVSPRQLR 138
Query: 136 RMEKIVLEKVCWKVKATTAFQFLQLYYSLLQENLPLERRNSINFERLEAQLKACHCRIIF 195
E +VL K+ W + A A FL + L + +LP +R+ + + + L C F
Sbjct: 139 DWEVLVLGKLKWDLAAVIAHDFLA--FILHRLSLPRDRQALVK-KHAQTFLALCATDYTF 195
Query: 196 SKAKPSVLALSIIALEIQAQKCVELTEGIECLQKHSKINGRD---LTFWQELVSKCLTE 251
+ PS++A I +Q ++ G E + + I G + L QE + L E
Sbjct: 196 AMYPPSMIATGSIGAAVQGLGACSMS-GDELTELLAGITGTEVDCLRACQEQIEAALRE 253
>gi|90669307 cyclin B3 isoform 3 [Homo sapiens]
Length = 1395
Score = 52.0 bits (123), Expect = 6e-07
Identities = 57/244 (23%), Positives = 102/244 (41%), Gaps = 36/244 (14%)
Query: 45 LRMTARLRDFEVKDLLSLTQFFGFDTETFSLAVNLLDRFLSKMKVQPKHLGCVGLSCFYL 104
+ +T+ +R V L+ + F ET LAV L+D +L K + L +G + F +
Sbjct: 1154 IEITSDMRAILVDWLVEVQVSFEMTHETLYLAVKLVDLYLMKAVCKKDKLQLLGATAFMI 1213
Query: 105 AVKSIEEERNVPLATDLIRISQYRFTVSDLMRMEKIVLEKVCWKVKATTAFQFLQLYYSL 164
A K EE N P D + I + S+++ ME +L + + A+ FL+ Y
Sbjct: 1214 AAKF--EEHNSPRVDDFVYICDDNYQRSEVLSMEINILNVLKCDINIPIAYHFLRRYARC 1271
Query: 165 LQENLPLERRNSINFERLEAQLKACHCRIIFSKAKPSVLALSIIALEIQAQKCVELTEGI 224
+ N+ + +++ E L+ H + + K S LA + + L + +K
Sbjct: 1272 IHTNM---KTLTLSRYICEMTLQEYH----YVQEKASKLAAASLLLALYMKK-------- 1316
Query: 225 ECLQKHSKINGRDLTFWQELVSKCLTEYSSNKCSK--PNVQKLKWIVSGRTARQLKHSYY 282
L +W L YS S+ P V++L +++ + LK YY
Sbjct: 1317 -------------LGYWVPF----LEHYSGYSISELHPLVRQLNKLLTFSSYDSLKAVYY 1359
Query: 283 RITH 286
+ +H
Sbjct: 1360 KYSH 1363
>gi|16306525 cyclin B3 isoform 1 [Homo sapiens]
Length = 291
Score = 50.1 bits (118), Expect = 2e-06
Identities = 63/262 (24%), Positives = 110/262 (41%), Gaps = 41/262 (15%)
Query: 27 CQPKVCGLRLIESAHDNGLRMTARLRDFEVKDLLSLTQFFGFDTETFSLAVNLLDRFLSK 86
CQ K+ L ES + L+ + R +DL +++ F ET LAV L+D +L K
Sbjct: 37 CQTKISPSSLQESP--SSLQGALKKRS-AFEDLTNVS--FEMTHETLYLAVKLVDLYLMK 91
Query: 87 MKVQPKHLGCVGLSCFYLAVKSIEEERNVPLATDLIRISQYRFTVSDLMRMEKIVLEKVC 146
+ L +G + F +A K EE N P D + I + S+++ ME +L +
Sbjct: 92 AVCKKDKLQLLGATAFMIAAKF--EEHNSPRVDDFVYICDDNYQRSEVLSMEINILNVLK 149
Query: 147 WKVKATTAFQFLQLYYSLLQENLPLERRNSINFERLEAQLKACHCRIIFSKAKPSVLALS 206
+ A+ FL+ Y + N+ + +++ E L+ H + + K S LA +
Sbjct: 150 CDINIPIAYHFLRRYARCIHTNM---KTLTLSRYICEMTLQEYH----YVQEKASKLAAA 202
Query: 207 IIALEIQAQKCVELTEGIECLQKHSKINGRDLTFWQELVSKCLTEYSSNKCSK--PNVQK 264
+ L + +K L +W L YS S+ P V++
Sbjct: 203 SLLLALYMKK---------------------LGYWVPF----LEHYSGYSISELHPLVRQ 237
Query: 265 LKWIVSGRTARQLKHSYYRITH 286
L +++ + LK YY+ +H
Sbjct: 238 LNKLLTFSSYDSLKAVYYKYSH 259
>gi|242247025 cyclin N-terminal domain containing 2 isoform 2 [Homo
sapiens]
Length = 307
Score = 48.9 bits (115), Expect = 5e-06
Identities = 30/103 (29%), Positives = 59/103 (57%), Gaps = 2/103 (1%)
Query: 47 MTARLRDFEVKDLLSLTQFFGFDTETFSLAVNLLDRFLSKMKVQPKHLGCVGLSCFYLAV 106
+T +R V L+ + ++ G +T LAV+LLD +LS +V+ L +G++C ++A
Sbjct: 103 VTPEMRALVVDWLVQVHEYLGLAGDTLYLAVHLLDSYLSAGRVRLHRLQLLGVACLFVAC 162
Query: 107 KSIEEERNVPLATDLIRISQYRFTVSDLMRMEKIVLEKVCWKV 149
K EE +P L +S F+ ++L+R E+ +L ++ +++
Sbjct: 163 KM--EECVLPEPAFLCLLSADSFSRAELLRAERRILSRLDFRL 203
>gi|197276676 cyclin J isoform 3 [Homo sapiens]
Length = 371
Score = 48.9 bits (115), Expect = 5e-06
Identities = 32/94 (34%), Positives = 46/94 (48%), Gaps = 5/94 (5%)
Query: 75 LAVNLLDRFLSKMKVQPKHLGCVGLSCFYLAVKSIEEERNVPLATDLIRIS-----QYRF 129
LAV LLD F+ + + + L V LSC LA K E+E +VP L +
Sbjct: 63 LAVYLLDLFMDRYDISIQQLHLVALSCLLLASKFEEKEDSVPKLEQLNSLGCMTNMNLVL 122
Query: 130 TVSDLMRMEKIVLEKVCWKVKATTAFQFLQLYYS 163
T +L+ ME ++LE W + TA F++ Y S
Sbjct: 123 TKQNLLHMELLLLETFQWNLCLPTAAHFIEYYLS 156
>gi|197276674 cyclin J isoform 1 [Homo sapiens]
Length = 383
Score = 48.9 bits (115), Expect = 5e-06
Identities = 32/94 (34%), Positives = 46/94 (48%), Gaps = 5/94 (5%)
Query: 75 LAVNLLDRFLSKMKVQPKHLGCVGLSCFYLAVKSIEEERNVPLATDLIRIS-----QYRF 129
LAV LLD F+ + + + L V LSC LA K E+E +VP L +
Sbjct: 63 LAVYLLDLFMDRYDISIQQLHLVALSCLLLASKFEEKEDSVPKLEQLNSLGCMTNMNLVL 122
Query: 130 TVSDLMRMEKIVLEKVCWKVKATTAFQFLQLYYS 163
T +L+ ME ++LE W + TA F++ Y S
Sbjct: 123 TKQNLLHMELLLLETFQWNLCLPTAAHFIEYYLS 156
>gi|40254889 cyclin J isoform 2 [Homo sapiens]
Length = 372
Score = 48.9 bits (115), Expect = 5e-06
Identities = 32/94 (34%), Positives = 46/94 (48%), Gaps = 5/94 (5%)
Query: 75 LAVNLLDRFLSKMKVQPKHLGCVGLSCFYLAVKSIEEERNVPLATDLIRIS-----QYRF 129
LAV LLD F+ + + + L V LSC LA K E+E +VP L +
Sbjct: 63 LAVYLLDLFMDRYDISIQQLHLVALSCLLLASKFEEKEDSVPKLEQLNSLGCMTNMNLVL 122
Query: 130 TVSDLMRMEKIVLEKVCWKVKATTAFQFLQLYYS 163
T +L+ ME ++LE W + TA F++ Y S
Sbjct: 123 TKQNLLHMELLLLETFQWNLCLPTAAHFIEYYLS 156
>gi|4757930 cyclin B2 [Homo sapiens]
Length = 398
Score = 48.1 bits (113), Expect = 9e-06
Identities = 33/117 (28%), Positives = 56/117 (47%), Gaps = 2/117 (1%)
Query: 43 NGLRMTARLRDFEVKDLLSLTQFFGFDTETFSLAVNLLDRFLSKMKVQPKHLGCVGLSCF 102
+G + R+R V L+ + F ET + V ++DRFL V K L VG++
Sbjct: 157 DGRDINGRMRAILVDWLVQVHSKFRLLQETLYMCVGIMDRFLQVQPVSRKKLQLVGITAL 216
Query: 103 YLAVKSIEEERNVPLATDLIRISQYRFTVSDLMRMEKIVLEKVCWKVKATTAFQFLQ 159
LA K EE P D + I+ +T S + ME ++L+++ +++ FL+
Sbjct: 217 LLASK--YEEMFSPNIEDFVYITDNAYTSSQIREMETLILKELKFELGRPLPLHFLR 271
>gi|153791755 cyclin domain containing [Homo sapiens]
Length = 350
Score = 47.8 bits (112), Expect = 1e-05
Identities = 47/171 (27%), Positives = 77/171 (45%), Gaps = 13/171 (7%)
Query: 46 RMTARLRDFEVKDLLSLTQFFGFDTETFSLAVNLLDRFLSKMKVQPKHLGCVGLSCFYLA 105
++TA R + L+ + + FG E+ L VN LDRFL+ V +G++ +A
Sbjct: 127 QVTAESRCKLLSWLIPVHRQFGLSFESLCLTVNTLDRFLTTTPVAADCFQLLGVTSLLIA 186
Query: 106 VKSIEEERNVPLATDLIRISQYRFTVSDLMRMEKIVLEKVCWKVKATTAFQFLQLYYSLL 165
K +E + P L+ + F+ L +E IVL K+ + + A T FL+ +
Sbjct: 187 CKQVEV--HPPRVKQLLALCCGAFSRQQLCNLECIVLHKLHFTLGAPTISFFLEHF---- 240
Query: 166 QENLPLERRNSINFERLEAQLKA------CHCRIIFSKAKPSVLALSIIAL 210
+ +E + E LEAQ A F+ PS+LA+ +AL
Sbjct: 241 -THARVEAGQAEASEALEAQALARGVAELSLADYAFTSYSPSLLAICCLAL 290
>gi|17318565 cyclin E2 [Homo sapiens]
Length = 404
Score = 46.6 bits (109), Expect = 3e-05
Identities = 29/113 (25%), Positives = 56/113 (49%), Gaps = 3/113 (2%)
Query: 50 RLRDFEVKDLLSLTQFFGFDTETFSLAVNLLDRFLSKMK-VQPKHLGCVGLSCFYLAVKS 108
++R + LL + + + ETF LA + DRF+ K + L +G++ ++A K
Sbjct: 140 QMRSILLDWLLEVCEVYTLHRETFYLAQDFFDRFMLTQKDINKNMLQLIGITSLFIASKL 199
Query: 109 IEEERNVPLATDLIRISQYRFTVSDLMRMEKIVLEKVCWKVKATTAFQFLQLY 161
EE P + ++ + D++RME I+L+ + W++ T +L L+
Sbjct: 200 --EEIYAPKLQEFAYVTDGACSEEDILRMELIILKALKWELCPVTIISWLNLF 250
>gi|209862835 cyclin D3 isoform 1 [Homo sapiens]
Length = 211
Score = 43.9 bits (102), Expect = 2e-04
Identities = 47/179 (26%), Positives = 78/179 (43%), Gaps = 11/179 (6%)
Query: 77 VNLLDRFLSKMKVQPKHLGCVGLSCFYLAVKSIEEERNVPLATDLIRI-SQYRFTVSDLM 135
+N LDR+LS + + L +G C LA K E PL + + I + + + L
Sbjct: 1 MNYLDRYLSCVPTRKAQLQLLGAVCMLLASKLRE---TTPLTIEKLCIYTDHAVSPRQLR 57
Query: 136 RMEKIVLEKVCWKVKATTAFQFLQLYYSLLQENLPLERRNSINFERLEAQLKACHCRIIF 195
E +VL K+ W + A A FL + L + +LP +R+ + + + L C F
Sbjct: 58 DWEVLVLGKLKWDLAAVIAHDFLA--FILHRLSLPRDRQALVK-KHAQTFLALCATDYTF 114
Query: 196 SKAKPSVLALSIIALEIQAQKCVELTEGIECLQKHSKINGRD---LTFWQELVSKCLTE 251
+ PS++A I +Q ++ G E + + I G + L QE + L E
Sbjct: 115 AMYPPSMIATGSIGAAVQGLGACSMS-GDELTELLAGITGTEVDCLRACQEQIEAALRE 172
>gi|14327896 cyclin B1 [Homo sapiens]
Length = 433
Score = 39.7 bits (91), Expect = 0.003
Identities = 33/139 (23%), Positives = 59/139 (42%), Gaps = 12/139 (8%)
Query: 21 LEQESRCQPKVCGLRLIESAHDNGLRMTARLRDFEVKDLLSLTQFFGFDTETFSLAVNLL 80
LE+E +PK G +T +R + L+ + F ET + V+++
Sbjct: 181 LEEEQAVRPKYL----------LGREVTGNMRAILIDWLVQVQMKFRLLQETMYMTVSII 230
Query: 81 DRFLSKMKVQPKHLGCVGLSCFYLAVKSIEEERNVPLATDLIRISQYRFTVSDLMRMEKI 140
DRF+ V K L VG++ ++A K EE P D ++ +T + +ME
Sbjct: 231 DRFMQNNCVPKKMLQLVGVTAMFIASK--YEEMYPPEIGDFAFVTDNTYTKHQIRQMEMK 288
Query: 141 VLEKVCWKVKATTAFQFLQ 159
+L + + + FL+
Sbjct: 289 ILRALNFGLGRPLPLHFLR 307
>gi|17318559 cyclin E1 isoform 1 [Homo sapiens]
Length = 410
Score = 38.5 bits (88), Expect = 0.007
Identities = 28/124 (22%), Positives = 59/124 (47%), Gaps = 7/124 (5%)
Query: 46 RMTARLRDFEVKDLLSLTQFFGFDTETFSLAVNLLDRFLSKMK-VQPKHLGCVGLSCFYL 104
+M A L D+ L+ + + + ETF LA + DR+++ + V L +G+S ++
Sbjct: 143 KMRAILLDW----LMEVCEVYKLHRETFYLAQDFFDRYMATQENVVKTLLQLIGISSLFI 198
Query: 105 AVKSIEEERNVPLATDLIRISQYRFTVSDLMRMEKIVLEKVCWKVKATTAFQFLQLYYSL 164
A K EE P ++ + +++ ME ++++ + W++ T +L +Y +
Sbjct: 199 AAKL--EEIYPPKLHQFAYVTDGACSGDEILTMELMIMKALKWRLSPLTIVSWLNVYMQV 256
Query: 165 LQEN 168
N
Sbjct: 257 AYLN 260
>gi|17318561 cyclin E1 isoform 2 [Homo sapiens]
Length = 395
Score = 38.5 bits (88), Expect = 0.007
Identities = 28/124 (22%), Positives = 59/124 (47%), Gaps = 7/124 (5%)
Query: 46 RMTARLRDFEVKDLLSLTQFFGFDTETFSLAVNLLDRFLSKMK-VQPKHLGCVGLSCFYL 104
+M A L D+ L+ + + + ETF LA + DR+++ + V L +G+S ++
Sbjct: 128 KMRAILLDW----LMEVCEVYKLHRETFYLAQDFFDRYMATQENVVKTLLQLIGISSLFI 183
Query: 105 AVKSIEEERNVPLATDLIRISQYRFTVSDLMRMEKIVLEKVCWKVKATTAFQFLQLYYSL 164
A K EE P ++ + +++ ME ++++ + W++ T +L +Y +
Sbjct: 184 AAKL--EEIYPPKLHQFAYVTDGACSGDEILTMELMIMKALKWRLSPLTIVSWLNVYMQV 241
Query: 165 LQEN 168
N
Sbjct: 242 AYLN 245
>gi|118572588 cyclin F [Homo sapiens]
Length = 786
Score = 33.9 bits (76), Expect = 0.18
Identities = 21/111 (18%), Positives = 50/111 (45%), Gaps = 2/111 (1%)
Query: 59 LLSLTQFFGFDTETFSLAVNLLDRFLSKMKVQPKHLGCVGLSCFYLAVKSIEEERNVPLA 118
L+ + F + L V +DR+L + V L +G++C + + I +E +
Sbjct: 317 LVEVATMKDFTSLCLHLTVECVDRYLRRRLVPRYRLQLLGIACMVICTRFISKE--ILTI 374
Query: 119 TDLIRISQYRFTVSDLMRMEKIVLEKVCWKVKATTAFQFLQLYYSLLQENL 169
+ + ++ + DL+RM ++ + K++ T + ++ +L+ L
Sbjct: 375 REAVWLTDNTYKYEDLVRMMGEIVSALEGKIRVPTVVDYKEVLLTLVPVEL 425
>gi|22538387 A-kinase anchor protein 9 isoform 2 [Homo sapiens]
Length = 3907
Score = 33.1 bits (74), Expect = 0.30
Identities = 43/206 (20%), Positives = 83/206 (40%), Gaps = 37/206 (17%)
Query: 51 LRDFEVKDLLSLTQFFGFDTETFSLAVNLLDRFLS-KMKVQPKHLGCVGLSCFYLAVKSI 109
L + +K L + T F F+ +NL R L + V K L L+ Y +K +
Sbjct: 2469 LTEDALKSLENQTYFKSFEENGKGSIINLETRLLQLESTVSAKDLE---LTQCYKQIKDM 2525
Query: 110 EEERNVPLATDLIRISQYRFTVSDLMRMEKIVLEKVCWKVKATTAFQFLQLYYSLLQENL 169
+E+ T++++ ++ ++KIV EKV + + + +Q Y Q+N
Sbjct: 2526 QEQGQ--FETEMLQ--------KKIVNLQKIVEEKVAAALVSQIQLEAVQEYAKFCQDNQ 2575
Query: 170 PL----ERRN-------------------SINFERLEAQLKACHCRIIFSKAKPSVLALS 206
+ ER N ++ LE+Q+ H +I K + + +
Sbjct: 2576 TISSEPERTNIQNLNQLREDELGSDISALTLRISELESQVVEMHTSLILEKEQVEIAEKN 2635
Query: 207 IIALEIQAQKCVELTEGIECLQKHSK 232
++ E + + +L EG E Q+ +
Sbjct: 2636 VLEKEKKLLELQKLLEGNEKKQREKE 2661
>gi|22538393 A-kinase anchor protein 9 isoform 3 [Homo sapiens]
Length = 3899
Score = 33.1 bits (74), Expect = 0.30
Identities = 43/206 (20%), Positives = 83/206 (40%), Gaps = 37/206 (17%)
Query: 51 LRDFEVKDLLSLTQFFGFDTETFSLAVNLLDRFLS-KMKVQPKHLGCVGLSCFYLAVKSI 109
L + +K L + T F F+ +NL R L + V K L L+ Y +K +
Sbjct: 2461 LTEDALKSLENQTYFKSFEENGKGSIINLETRLLQLESTVSAKDLE---LTQCYKQIKDM 2517
Query: 110 EEERNVPLATDLIRISQYRFTVSDLMRMEKIVLEKVCWKVKATTAFQFLQLYYSLLQENL 169
+E+ T++++ ++ ++KIV EKV + + + +Q Y Q+N
Sbjct: 2518 QEQGQ--FETEMLQ--------KKIVNLQKIVEEKVAAALVSQIQLEAVQEYAKFCQDNQ 2567
Query: 170 PL----ERRN-------------------SINFERLEAQLKACHCRIIFSKAKPSVLALS 206
+ ER N ++ LE+Q+ H +I K + + +
Sbjct: 2568 TISSEPERTNIQNLNQLREDELGSDISALTLRISELESQVVEMHTSLILEKEQVEIAEKN 2627
Query: 207 IIALEIQAQKCVELTEGIECLQKHSK 232
++ E + + +L EG E Q+ +
Sbjct: 2628 VLEKEKKLLELQKLLEGNEKKQREKE 2653
>gi|76257392 ubiquitin specific protease 48 isoform b [Homo sapiens]
Length = 485
Score = 30.4 bits (67), Expect = 1.9
Identities = 29/133 (21%), Positives = 57/133 (42%), Gaps = 4/133 (3%)
Query: 154 AFQFLQLYYSLLQENLPLERRNSI-NFERLEAQLKACHCRIIFSKAKPSVLALSIIALEI 212
A +F +L+ SLL++ L ++ + N + + + + + + S L LE+
Sbjct: 182 AQEFSKLFMSLLEDTLSKQKNPDVRNIVQQQFCGEYAYVTVCNQCGRESKLLSKFYELEL 241
Query: 213 QAQKCVELTEGIECLQKHSKINGRDLTFWQELVSKCLTEYSSNKCSKP---NVQKLKWIV 269
Q +LT+ I K K+ G + F + SK S P N+Q ++++
Sbjct: 242 NIQGHKQLTDCISEFLKEEKLEGDNRYFCENCQSKQNATRKIRLLSLPCTLNLQLMRFVF 301
Query: 270 SGRTARQLKHSYY 282
+T + K + Y
Sbjct: 302 DRQTGHKKKLNTY 314
Database: hs.faa
Posted date: Aug 4, 2009 4:42 PM
Number of letters in database: 18,247,518
Number of sequences in database: 37,866
Lambda K H
0.323 0.135 0.398
Gapped
Lambda K H
0.267 0.0410 0.140
Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Hits to DB: 9,958,445
Number of Sequences: 37866
Number of extensions: 392312
Number of successful extensions: 1295
Number of sequences better than 10.0: 30
Number of HSP's better than 10.0 without gapping: 23
Number of HSP's successfully gapped in prelim test: 13
Number of HSP's that attempted gapping in prelim test: 1258
Number of HSP's gapped (non-prelim): 37
length of query: 295
length of database: 18,247,518
effective HSP length: 102
effective length of query: 193
effective length of database: 14,385,186
effective search space: 2776340898
effective search space used: 2776340898
T: 11
A: 40
X1: 16 ( 7.5 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 40 (21.5 bits)
S2: 61 (28.1 bits)
Search results were obtained with NCBI BLAST and RefSeq entries.
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Guide to the Human Genome
Copyright © 2010 by Stewart Scherer. All rights reserved.