Guide to the Human Genome
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Name: HFE2 Sequence: fasta or formatted (426aa) NCBI GI: 47458048
Description:

hemojuvelin isoform a precursor

Referenced in:

Iron, Copper, and Arsenic Metabolism

Other entries for this name:
alt prot [200aa] hemojuvelin isoform c
alt prot [313aa] hemojuvelin isoform b
alt prot [200aa] hemojuvelin isoform c
Composition:

amino acid map
 Amino acid        Percentage    Count  Longest homopolymer
 A alanine             9.6         41           2
 C cysteine            3.8         16           1
 D aspartate           4.7         20           1
 E glutamate           3.5         15           1
 F phenylalanine       4.2         18           1
 G glycine            11.3         48           6
 H histidine           3.8         16           3
 I isoleucine          4.2         18           3
 K lysine              1.6          7           1
 L leucine            11.0         47           5
 M methionine          1.2          5           1
 N asparagine          2.6         11           1
 P proline             7.3         31           4
 Q glutamine           4.2         18           1
 R arginine            6.8         29           2
 S serine              8.9         38           2
 T threonine           4.9         21           2
 V valine              4.5         19           1
 W tryptophan          0.5          2           1
 Y tyrosine            1.4          6           1
Comparative genomics:

Search single species RefSeq proteins at NCBI
   H. sapiens
   M. musculus
   D. rerio
   C. intestinalis
   S. purpuratus
   D. melanogaster
   C. elegans
   A. thaliana
   S. cerevisiae
   E. coli W3110
   A. pernix K1

Search summary

comparative genomics plot

   Figure data

Additional searches of
RefSeq proteins at NCBI

   All
   Eukaryotes
   Bacteria
   Archaea
   Viruses
   Primates
   Mammals
   Vertebrates

Related human proteins:
Protein          Relative score         Description

Self-match            1.000   hemojuvelin isoform a precursor 
HFE2                  0.728   hemojuvelin isoform b 
HFE2                  0.440   hemojuvelin isoform c 
HFE2                  0.440   hemojuvelin isoform c 
RGMA                  0.401   RGM domain family, member A 
RGMB                  0.358   RGM domain family, member B 
EVX2                  0.020   even-skipped homeobox 2 
SHANK1                0.019   SH3 and multiple ankyrin repeat domains 1 
FAM98B                0.016   family with sequence similarity 98, member B isofor...
RFX1                  0.015   regulatory factor X1 
SLC4A5                0.015   sodium bicarbonate transporter 4 isoform a 
SLC4A5                0.015   sodium bicarbonate transporter 4 isoform c 
SHOX2                 0.015   short stature homeobox 2 isoform a 
GAR1                  0.015   nucleolar protein family A, member 1 
GAR1                  0.015   nucleolar protein family A, member 1 
CACNG8                0.015   voltage-dependent calcium channel gamma-8 subunit [H...
TMEM163               0.015   transmembrane protein 163 
FBL                   0.014   fibrillarin 
ANKS1A                0.014   ankyrin repeat and sterile alpha motif domain conta...
ZFHX3                 0.014   AT-binding transcription factor 1 
LRCH2                 0.014   leucine-rich repeats and calponin homology (CH) dom...
SRP68                 0.014   signal recognition particle 68kDa 
HOXB3                 0.014   homeobox B3 
AR                    0.014   androgen receptor isoform 1 
FLJ31945              0.014   PREDICTED: hypothetical protein 
FLJ31945              0.014   PREDICTED: hypothetical protein 
FLJ31945              0.014   PREDICTED: hypothetical protein 
FIZ1                  0.014   FLT3-interacting zinc finger 1 
ARID1B                0.014   AT rich interactive domain 1B (SWI1-like) isoform 2 ...
ARID1B                0.014   AT rich interactive domain 1B (SWI1-like) isoform 1 ...
Human BLASTP results (used to prepare the table)

Gene descriptions are from NCBI RefSeq. Search results were obtained with NCBI BLAST and RefSeq entries. When identical proteins are present, the self-match may not be listed first in BLASTP output. In such cases, the table above has been reordered to place it first.

See About the Figures for the scoring system used in the figure above right. The same scoring system was used in the table of BLASTP results.


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Guide to the Human Genome
Copyright © 2010 by Stewart Scherer. All rights reserved.

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