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Search of human proteins with 47174859
BLASTP 2.2.11 [Jun-05-2005]
Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer,
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997),
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs", Nucleic Acids Res. 25:3389-3402.
Query= gi|47174859 tripartite motif-containing 46 [Homo sapiens]
(759 letters)
Database: hs.faa
37,866 sequences; 18,247,518 total letters
Searching..................................................done
Score E
Sequences producing significant alignments: (bits) Value
gi|47174859 tripartite motif-containing 46 [Homo sapiens] 1556 0.0
gi|62865606 tripartite motif-containing 36 isoform 1 [Homo sapiens] 619 e-177
gi|148833499 midline 1 [Homo sapiens] 213 7e-55
gi|4557753 midline 1 [Homo sapiens] 213 7e-55
gi|15451852 midline 1 [Homo sapiens] 213 7e-55
gi|223890259 midline 2 isoform 2 [Homo sapiens] 205 1e-52
gi|223890257 midline 2 isoform 1 [Homo sapiens] 196 5e-50
gi|190341104 tripartite motif protein 9 isoform 1 [Homo sapiens] 177 3e-44
gi|16519559 tripartite motif protein 9 isoform 2 [Homo sapiens] 171 2e-42
gi|134288906 tripartite motif-containing 67 [Homo sapiens] 159 9e-39
gi|19924163 muscle specific ring finger protein 1 [Homo sapiens] 150 4e-36
gi|78482626 ring finger protein 30 isoform 2 [Homo sapiens] 145 2e-34
gi|34878844 tripartite motif-containing 55 isoform 3 [Homo sapiens] 143 5e-34
gi|34878836 tripartite motif-containing 55 isoform 1 [Homo sapiens] 143 5e-34
gi|34878821 tripartite motif-containing 55 isoform 2 [Homo sapiens] 143 5e-34
gi|78482627 ring finger protein 30 isoform 1 [Homo sapiens] 124 2e-28
gi|89886468 fibronectin type III and SPRY domain containing 1-li... 119 8e-27
gi|223718222 fibronectin type III and SPRY domain containing 1-l... 118 2e-26
gi|13236585 fibronectin type III and SPRY domain containing 1 [H... 117 4e-26
gi|34878852 tripartite motif-containing 55 isoform 4 [Homo sapiens] 98 3e-20
gi|28195390 tripartite motif-containing 42 [Homo sapiens] 87 6e-17
gi|54792146 tripartite motif-containing 47 [Homo sapiens] 81 4e-15
gi|224548923 tripartite motif-containing 45 isoform 2 [Homo sapi... 78 3e-14
gi|224548921 tripartite motif-containing 45 isoform 1 [Homo sapi... 78 3e-14
gi|148596968 tripartite motif-containing 8 [Homo sapiens] 70 9e-12
gi|55741632 fibronectin type III and SPRY domain containing 2 [H... 69 1e-11
gi|47419911 transcriptional intermediary factor 1 alpha isoform ... 68 3e-11
gi|47419909 transcriptional intermediary factor 1 alpha isoform ... 68 3e-11
gi|27436877 tripartite motif-containing 59 [Homo sapiens] 66 1e-10
gi|149193331 tripartite motif protein 15 [Homo sapiens] 66 1e-10
>gi|47174859 tripartite motif-containing 46 [Homo sapiens]
Length = 759
Score = 1556 bits (4029), Expect = 0.0
Identities = 759/759 (100%), Positives = 759/759 (100%)
Query: 1 MAEGEDMQTFTSIMDALVRISTSMKNMEKELLCPVCQEMYKQPLVLPCTHNVCQACAREV 60
MAEGEDMQTFTSIMDALVRISTSMKNMEKELLCPVCQEMYKQPLVLPCTHNVCQACAREV
Sbjct: 1 MAEGEDMQTFTSIMDALVRISTSMKNMEKELLCPVCQEMYKQPLVLPCTHNVCQACAREV 60
Query: 61 LGQQGYIGHGGDPSSEPTSPASTPSTRSPRLSRRTLPKPDRLDRLLKSGFGTYPGRKRGA 120
LGQQGYIGHGGDPSSEPTSPASTPSTRSPRLSRRTLPKPDRLDRLLKSGFGTYPGRKRGA
Sbjct: 61 LGQQGYIGHGGDPSSEPTSPASTPSTRSPRLSRRTLPKPDRLDRLLKSGFGTYPGRKRGA 120
Query: 121 LHPQVIMFPCPACQGDVELGERGLAGLFRNLTLERVVERYRQSVSVGGAILCQLCKPPPL 180
LHPQVIMFPCPACQGDVELGERGLAGLFRNLTLERVVERYRQSVSVGGAILCQLCKPPPL
Sbjct: 121 LHPQVIMFPCPACQGDVELGERGLAGLFRNLTLERVVERYRQSVSVGGAILCQLCKPPPL 180
Query: 181 EATKGCTECRATFCNECFKLFHPWGTQKAQHEPTLPTLSFRPKGLMCPDHKEEVTHYCKT 240
EATKGCTECRATFCNECFKLFHPWGTQKAQHEPTLPTLSFRPKGLMCPDHKEEVTHYCKT
Sbjct: 181 EATKGCTECRATFCNECFKLFHPWGTQKAQHEPTLPTLSFRPKGLMCPDHKEEVTHYCKT 240
Query: 241 CQRLVCQLCRVRRTHSGHKITPVLSAYQALKDKLTKSLTYILGNQDTVQTQICELEEAVR 300
CQRLVCQLCRVRRTHSGHKITPVLSAYQALKDKLTKSLTYILGNQDTVQTQICELEEAVR
Sbjct: 241 CQRLVCQLCRVRRTHSGHKITPVLSAYQALKDKLTKSLTYILGNQDTVQTQICELEEAVR 300
Query: 301 HTEVSGQQAKEEVSQLVRGLGAVLEEKRASLLQAIEECQQERLARLSAQIQEHRSLLDGS 360
HTEVSGQQAKEEVSQLVRGLGAVLEEKRASLLQAIEECQQERLARLSAQIQEHRSLLDGS
Sbjct: 301 HTEVSGQQAKEEVSQLVRGLGAVLEEKRASLLQAIEECQQERLARLSAQIQEHRSLLDGS 360
Query: 361 GLVGYAQEVLKETDQPCFVQAAKQLHNRIARATEALQTFRPAASSSFRHCQLDVGREMKL 420
GLVGYAQEVLKETDQPCFVQAAKQLHNRIARATEALQTFRPAASSSFRHCQLDVGREMKL
Sbjct: 361 GLVGYAQEVLKETDQPCFVQAAKQLHNRIARATEALQTFRPAASSSFRHCQLDVGREMKL 420
Query: 421 LTELNFLRVPEAPVIDTQRTFAYDQIFLCWRLPPHSPPAWHYTVEFRRTDVPAQPGPTRW 480
LTELNFLRVPEAPVIDTQRTFAYDQIFLCWRLPPHSPPAWHYTVEFRRTDVPAQPGPTRW
Sbjct: 421 LTELNFLRVPEAPVIDTQRTFAYDQIFLCWRLPPHSPPAWHYTVEFRRTDVPAQPGPTRW 480
Query: 481 QRREEVRGTSALLENPDTGSVYVLRVRGCNKAGYGEYSEDVHLHTPPAPVLHFFLDSRWG 540
QRREEVRGTSALLENPDTGSVYVLRVRGCNKAGYGEYSEDVHLHTPPAPVLHFFLDSRWG
Sbjct: 481 QRREEVRGTSALLENPDTGSVYVLRVRGCNKAGYGEYSEDVHLHTPPAPVLHFFLDSRWG 540
Query: 541 ASRERLAISKDQRAVRSVPGLPLLLAADRLLTGCHLSVDVVLGDVAVTQGRSYWACAVDP 600
ASRERLAISKDQRAVRSVPGLPLLLAADRLLTGCHLSVDVVLGDVAVTQGRSYWACAVDP
Sbjct: 541 ASRERLAISKDQRAVRSVPGLPLLLAADRLLTGCHLSVDVVLGDVAVTQGRSYWACAVDP 600
Query: 601 ASYLVKVGVGLESKLQESFQGAPDVISPRYDPDSGHDSGAEDATVEASPPFAFLTIGMGK 660
ASYLVKVGVGLESKLQESFQGAPDVISPRYDPDSGHDSGAEDATVEASPPFAFLTIGMGK
Sbjct: 601 ASYLVKVGVGLESKLQESFQGAPDVISPRYDPDSGHDSGAEDATVEASPPFAFLTIGMGK 660
Query: 661 ILLGSGASSNAGLTGRDGPTAGCTVPLPPRLGICLDYERGRVSFLDAVSFRGLLECPLDC 720
ILLGSGASSNAGLTGRDGPTAGCTVPLPPRLGICLDYERGRVSFLDAVSFRGLLECPLDC
Sbjct: 661 ILLGSGASSNAGLTGRDGPTAGCTVPLPPRLGICLDYERGRVSFLDAVSFRGLLECPLDC 720
Query: 721 SGPVCPAFCFIGGGAVQLQEPVGTKPERKVTIGGFAKLD 759
SGPVCPAFCFIGGGAVQLQEPVGTKPERKVTIGGFAKLD
Sbjct: 721 SGPVCPAFCFIGGGAVQLQEPVGTKPERKVTIGGFAKLD 759
>gi|62865606 tripartite motif-containing 36 isoform 1 [Homo sapiens]
Length = 728
Score = 619 bits (1596), Expect = e-177
Identities = 318/749 (42%), Positives = 468/749 (62%), Gaps = 33/749 (4%)
Query: 1 MAEGEDMQTFTSIMDALVRISTSMKNMEKELLCPVCQEMYKQPLVLPCTHNVCQACAREV 60
M+E +M F IM+ + + ++KN+E+EL+CP C+E++ PL+LPC H++C C +E+
Sbjct: 1 MSESGEMSEFGYIMELIAKGKVTIKNIERELICPACKELFTHPLILPCQHSICHKCVKEL 60
Query: 61 LG--QQGYIGHGGDPSSEPTSPASTPSTRSPRLSRRTLPKPDRLDRLLKSGFGTYPGRKR 118
L + G D S++ SPRL R P D++DR+ + PG KR
Sbjct: 61 LLTLDDSFNDVGSDNSNQS----------SPRL-RLPSPSMDKIDRINR------PGWKR 103
Query: 119 GALHPQVIMFPCPACQGDVELGERGLAGLFRNLTLERVVERYRQSVSVGGAILCQLCKPP 178
+L P+ +FPCP C+ DV+LGERG+ GLFRN TLE +VERYRQ+ AI+C LCKPP
Sbjct: 104 NSLTPRTTVFPCPGCEHDVDLGERGINGLFRNFTLETIVERYRQAARAATAIMCDLCKPP 163
Query: 179 PLEATKGCTECRATFCNECFKLFHPWGTQKAQHEPTLPTLSFRPKGLMCPDHK-EEVTHY 237
P E+TK C +C A++CNECFK+ HPWGT KAQHE PT +FRPK LMCP+H+ E + Y
Sbjct: 164 PQESTKSCMDCSASYCNECFKIHHPWGTIKAQHEYVGPTTNFRPKILMCPEHETERINMY 223
Query: 238 CKTCQRLVCQLCRVRRTHSGHKITPVLSAYQALKDKLTKSLTYILGNQDTVQTQICELEE 297
C+ C+R VC LC++ H+ H++T + SAY+ LK+KL+K + Y++G + V++QI EL
Sbjct: 224 CELCRRPVCHLCKLGGNHANHRVTTMSSAYKTLKEKLSKDIDYLIGKESQVKSQISELNL 283
Query: 298 AVRHTEVSGQQAKEEVSQLVRGLGAVLEEKRASLLQAIEECQQERLARLSAQIQEHRSLL 357
++ TE +G++AKEE L VLEE+++S+L+AI+ ++ RL + Q++E++ LL
Sbjct: 284 LMKETECNGERAKEEAITHFEKLFEVLEERKSSVLKAIDSSKKLRLDKFQTQMEEYQGLL 343
Query: 358 DGSGLVGYAQEVLKETDQPCFVQAAKQLHNRIARATEALQTFRPAASSSFRHCQLDVGRE 417
+ +GLVGYAQEVLKETDQ CFVQ AKQLH RI +ATE+L++FRPAA +SF ++ ++
Sbjct: 344 ENNGLVGYAQEVLKETDQSCFVQTAKQLHLRIQKATESLKSFRPAAQTSFEDYVVNTSKQ 403
Query: 418 MKLLTELNFLRVP-EAPVIDTQRTFAYDQIFLCWRLPPHSPPAWHYTVEFRRTDVPAQPG 476
+LL EL+F + P I+ +++ Y+ + W P A Y +E+R+ + +
Sbjct: 404 TELLGELSFFSSGIDVPEINEEQSKVYNNALINWH-HPEKDKADSYVLEYRKIN---RDD 459
Query: 477 PTRWQRREEVRGTSALLENPDTGSVYVLRVRGCNKAGYGEYSEDVHLHTPPAPVLHFFLD 536
W EV GTS ++++ + S Y RVR + S ++ LHTPPAPV F D
Sbjct: 460 EMSW-NEIEVCGTSKIIQDLENSSTYAFRVRAYKGSICSPCSRELILHTPPAPVFSFLFD 518
Query: 537 SRWGASRERLAISKDQRAVRSVPGLPLLLAADRLLTGCHLSVDVVLGDVAVTQGRSYWAC 596
+ G + E L ++ + V S G LLLAA+R+ G + S+D ++GD +T+G+ +WA
Sbjct: 519 EKCGYNNEHLLLNLKRDRVESRAGFNLLLAAERIQVGYYTSLDYIIGDTGITKGKHFWAF 578
Query: 597 AVDPASYLVKVGVGLESKLQESFQGAPDVISPRYDPDSGHDSGAEDATVEASPPFAFLTI 656
V+P SYLVKVGV KLQE + D +SPRY+ DSGHDSG+EDA ++S PF +TI
Sbjct: 579 RVEPYSYLVKVGVASSDKLQEWLRSPRDAVSPRYEQDSGHDSGSEDACFDSSQPFTLVTI 638
Query: 657 GMGKILLGSGASSNAGLTGRDGPTAGCTVPLPPRLGICLDYERGRVSFLDAVSFRGLLEC 716
GM K + +S+ R +P+P +GI LD ++G+V F D + L E
Sbjct: 639 GMQKFFIPKSPTSSNEPENR-------VLPMPTSIGIFLDCDKGKVDFYDMDQMKCLYER 691
Query: 717 PLDCSGPVCPAFCFIGGGAVQLQEPVGTK 745
+DCS + PAF +G G +QL+EP+ K
Sbjct: 692 QVDCSHTLYPAFALMGSGGIQLEEPITAK 720
>gi|148833499 midline 1 [Homo sapiens]
Length = 667
Score = 213 bits (541), Expect = 7e-55
Identities = 183/743 (24%), Positives = 311/743 (41%), Gaps = 140/743 (18%)
Query: 24 MKNMEKELLCPVCQEMYKQPLVLPCTHNVCQACAREVLGQQGYIGHGGDPSSEPTSPAST 83
M+ +E EL CP+C E+++ PL+LPC H++C CA +L + H A+
Sbjct: 1 METLESELTCPICLELFEDPLLLPCAHSLCFNCAHRIL-----VSHC----------ATN 45
Query: 84 PSTRSPRLSRRTLPKPDRLDRLLKSGFGTYPGRKRGALHPQVIMFPCPACQGDVELGERG 143
S S + F CP C+ + L +RG
Sbjct: 46 ESVES------------------------------------ITAFQCPTCRHVITLSQRG 69
Query: 144 LAGLFRNLTLERVVERYRQSVSVGGA----------------------ILCQLC-KPPPL 180
L GL RN+TL+ +++R+ Q SV G +LCQ C + P
Sbjct: 70 LDGLKRNVTLQNIIDRF-QKASVSGPNSPSETRRERAFDANTMTSAEKVLCQFCDQDPAQ 128
Query: 181 EATKGCTECRATFCNECFKLFHPWGTQKAQHEPTLPTLSFRPKGLMCPDHKEE-VTHYCK 239
+A K C C ++C+EC K HP H P +GLMC +H++E V YC
Sbjct: 129 DAVKTCVTCEVSYCDECLKATHPNKKPFTGHRLIEPIPDSHIRGLMCLEHEDEKVNMYCV 188
Query: 240 TCQRLVCQLCRVRRTHSGHKITPVLSAYQALKDKLTKSLTYILGNQDTVQTQICELEEAV 299
T +L+C LC++ H H++ + Y LK L +LT ++ ++T + +L +
Sbjct: 189 TDDQLICALCKLVGRHRDHQVAALSERYDKLKQNLESNLTNLIKRNTELETLLAKLIQTC 248
Query: 300 RHTEVSGQQAKEEVSQLVRGLGAVLEEKRASLLQAIEECQQERLARLSAQIQEHRSLLDG 359
+H EV+ + + ++++ L +++++R + I+E + RL +L+ QI + ++
Sbjct: 249 QHVEVNASRQEAKLTEECDLLIEIIQQRRQIIGTKIKEGKVMRLRKLAQQIANCKQCIER 308
Query: 360 S-GLVGYAQEVLKETDQPCFVQAAKQLHNRIARATEALQTFRPA--ASSSFRHCQLDVGR 416
S L+ A+ LKE D F+Q AK + R++ AT + Q P + +F LD R
Sbjct: 309 SASLISQAEHSLKENDHARFLQTAKNITERVSMATASSQVLIPEINLNDTFDTFALDFSR 368
Query: 417 EMKLLTELNFLRVPEAPVIDTQR-TFAYDQIFLCWRLPPHSPPAWH---YTVEFRRTDVP 472
E KLL L++L P P I + T +YD I + W + YT+ + +V
Sbjct: 369 EKKLLECLDYLTAPNPPTIREELCTASYDTITVHWTSDDEFSVVSYELQYTIFTGQANVV 428
Query: 473 AQ-PGPTRWQRREEVRGTSALLENPDTGSVYVLRVRGCNKAGYGEYSEDVHLHTPPAPVL 531
+ W ++ + +G+ Y+ V+ N+AG SE L T P
Sbjct: 429 SLCNSADSWMIVPNIKQNHYTVHGLQSGTKYIFMVKAINQAG-SRSSEPGKLKTNSQP-- 485
Query: 532 HFFLDSRWGASRERLAISKDQRAV-RSVPGLPLLLAADRLLTGCHLSVDVVLGDVAVTQG 590
F LD + ++ +L +S D V R +R + V G+V + G
Sbjct: 486 -FKLDPK--SAHRKLKVSHDNLTVERDESSSKKSHTPERFTSQGSYG---VAGNVFIDSG 539
Query: 591 RSYWACAVDPASYLVKVGVGLESKLQESFQGAPDVISPRYDPDSGHDSGAEDATVEASPP 650
R YW + +++ +G+ +S +P+++
Sbjct: 540 RHYWEVVISGSTWYA-IGLAYKS-------------APKHE------------------- 566
Query: 651 FAFLTIGMGKILLGSGASSNAGLTGRDGPTAGCTVPLPP-----RLGICLDYERGRVSFL 705
IG +N + + +P+ P R+GI LDY+ G ++F
Sbjct: 567 ----WIGKNSASWALCRCNNNWVVRHNSK----EIPIEPAPHLRRVGILLDYDNGSIAFY 618
Query: 706 DAVSFRGLLECPLDCSGPVCPAF 728
DA++ L + + PVCP F
Sbjct: 619 DALNSIHLYTFDVAFAQPVCPTF 641
>gi|4557753 midline 1 [Homo sapiens]
Length = 667
Score = 213 bits (541), Expect = 7e-55
Identities = 183/743 (24%), Positives = 311/743 (41%), Gaps = 140/743 (18%)
Query: 24 MKNMEKELLCPVCQEMYKQPLVLPCTHNVCQACAREVLGQQGYIGHGGDPSSEPTSPAST 83
M+ +E EL CP+C E+++ PL+LPC H++C CA +L + H A+
Sbjct: 1 METLESELTCPICLELFEDPLLLPCAHSLCFNCAHRIL-----VSHC----------ATN 45
Query: 84 PSTRSPRLSRRTLPKPDRLDRLLKSGFGTYPGRKRGALHPQVIMFPCPACQGDVELGERG 143
S S + F CP C+ + L +RG
Sbjct: 46 ESVES------------------------------------ITAFQCPTCRHVITLSQRG 69
Query: 144 LAGLFRNLTLERVVERYRQSVSVGGA----------------------ILCQLC-KPPPL 180
L GL RN+TL+ +++R+ Q SV G +LCQ C + P
Sbjct: 70 LDGLKRNVTLQNIIDRF-QKASVSGPNSPSETRRERAFDANTMTSAEKVLCQFCDQDPAQ 128
Query: 181 EATKGCTECRATFCNECFKLFHPWGTQKAQHEPTLPTLSFRPKGLMCPDHKEE-VTHYCK 239
+A K C C ++C+EC K HP H P +GLMC +H++E V YC
Sbjct: 129 DAVKTCVTCEVSYCDECLKATHPNKKPFTGHRLIEPIPDSHIRGLMCLEHEDEKVNMYCV 188
Query: 240 TCQRLVCQLCRVRRTHSGHKITPVLSAYQALKDKLTKSLTYILGNQDTVQTQICELEEAV 299
T +L+C LC++ H H++ + Y LK L +LT ++ ++T + +L +
Sbjct: 189 TDDQLICALCKLVGRHRDHQVAALSERYDKLKQNLESNLTNLIKRNTELETLLAKLIQTC 248
Query: 300 RHTEVSGQQAKEEVSQLVRGLGAVLEEKRASLLQAIEECQQERLARLSAQIQEHRSLLDG 359
+H EV+ + + ++++ L +++++R + I+E + RL +L+ QI + ++
Sbjct: 249 QHVEVNASRQEAKLTEECDLLIEIIQQRRQIIGTKIKEGKVMRLRKLAQQIANCKQCIER 308
Query: 360 S-GLVGYAQEVLKETDQPCFVQAAKQLHNRIARATEALQTFRPA--ASSSFRHCQLDVGR 416
S L+ A+ LKE D F+Q AK + R++ AT + Q P + +F LD R
Sbjct: 309 SASLISQAEHSLKENDHARFLQTAKNITERVSMATASSQVLIPEINLNDTFDTFALDFSR 368
Query: 417 EMKLLTELNFLRVPEAPVIDTQR-TFAYDQIFLCWRLPPHSPPAWH---YTVEFRRTDVP 472
E KLL L++L P P I + T +YD I + W + YT+ + +V
Sbjct: 369 EKKLLECLDYLTAPNPPTIREELCTASYDTITVHWTSDDEFSVVSYELQYTIFTGQANVV 428
Query: 473 AQ-PGPTRWQRREEVRGTSALLENPDTGSVYVLRVRGCNKAGYGEYSEDVHLHTPPAPVL 531
+ W ++ + +G+ Y+ V+ N+AG SE L T P
Sbjct: 429 SLCNSADSWMIVPNIKQNHYTVHGLQSGTKYIFMVKAINQAG-SRSSEPGKLKTNSQP-- 485
Query: 532 HFFLDSRWGASRERLAISKDQRAV-RSVPGLPLLLAADRLLTGCHLSVDVVLGDVAVTQG 590
F LD + ++ +L +S D V R +R + V G+V + G
Sbjct: 486 -FKLDPK--SAHRKLKVSHDNLTVERDESSSKKSHTPERFTSQGSYG---VAGNVFIDSG 539
Query: 591 RSYWACAVDPASYLVKVGVGLESKLQESFQGAPDVISPRYDPDSGHDSGAEDATVEASPP 650
R YW + +++ +G+ +S +P+++
Sbjct: 540 RHYWEVVISGSTWYA-IGLAYKS-------------APKHE------------------- 566
Query: 651 FAFLTIGMGKILLGSGASSNAGLTGRDGPTAGCTVPLPP-----RLGICLDYERGRVSFL 705
IG +N + + +P+ P R+GI LDY+ G ++F
Sbjct: 567 ----WIGKNSASWALCRCNNNWVVRHNSK----EIPIEPAPHLRRVGILLDYDNGSIAFY 618
Query: 706 DAVSFRGLLECPLDCSGPVCPAF 728
DA++ L + + PVCP F
Sbjct: 619 DALNSIHLYTFDVAFAQPVCPTF 641
>gi|15451852 midline 1 [Homo sapiens]
Length = 667
Score = 213 bits (541), Expect = 7e-55
Identities = 183/743 (24%), Positives = 311/743 (41%), Gaps = 140/743 (18%)
Query: 24 MKNMEKELLCPVCQEMYKQPLVLPCTHNVCQACAREVLGQQGYIGHGGDPSSEPTSPAST 83
M+ +E EL CP+C E+++ PL+LPC H++C CA +L + H A+
Sbjct: 1 METLESELTCPICLELFEDPLLLPCAHSLCFNCAHRIL-----VSHC----------ATN 45
Query: 84 PSTRSPRLSRRTLPKPDRLDRLLKSGFGTYPGRKRGALHPQVIMFPCPACQGDVELGERG 143
S S + F CP C+ + L +RG
Sbjct: 46 ESVES------------------------------------ITAFQCPTCRHVITLSQRG 69
Query: 144 LAGLFRNLTLERVVERYRQSVSVGGA----------------------ILCQLC-KPPPL 180
L GL RN+TL+ +++R+ Q SV G +LCQ C + P
Sbjct: 70 LDGLKRNVTLQNIIDRF-QKASVSGPNSPSETRRERAFDANTMTSAEKVLCQFCDQDPAQ 128
Query: 181 EATKGCTECRATFCNECFKLFHPWGTQKAQHEPTLPTLSFRPKGLMCPDHKEE-VTHYCK 239
+A K C C ++C+EC K HP H P +GLMC +H++E V YC
Sbjct: 129 DAVKTCVTCEVSYCDECLKATHPNKKPFTGHRLIEPIPDSHIRGLMCLEHEDEKVNMYCV 188
Query: 240 TCQRLVCQLCRVRRTHSGHKITPVLSAYQALKDKLTKSLTYILGNQDTVQTQICELEEAV 299
T +L+C LC++ H H++ + Y LK L +LT ++ ++T + +L +
Sbjct: 189 TDDQLICALCKLVGRHRDHQVAALSERYDKLKQNLESNLTNLIKRNTELETLLAKLIQTC 248
Query: 300 RHTEVSGQQAKEEVSQLVRGLGAVLEEKRASLLQAIEECQQERLARLSAQIQEHRSLLDG 359
+H EV+ + + ++++ L +++++R + I+E + RL +L+ QI + ++
Sbjct: 249 QHVEVNASRQEAKLTEECDLLIEIIQQRRQIIGTKIKEGKVMRLRKLAQQIANCKQCIER 308
Query: 360 S-GLVGYAQEVLKETDQPCFVQAAKQLHNRIARATEALQTFRPA--ASSSFRHCQLDVGR 416
S L+ A+ LKE D F+Q AK + R++ AT + Q P + +F LD R
Sbjct: 309 SASLISQAEHSLKENDHARFLQTAKNITERVSMATASSQVLIPEINLNDTFDTFALDFSR 368
Query: 417 EMKLLTELNFLRVPEAPVIDTQR-TFAYDQIFLCWRLPPHSPPAWH---YTVEFRRTDVP 472
E KLL L++L P P I + T +YD I + W + YT+ + +V
Sbjct: 369 EKKLLECLDYLTAPNPPTIREELCTASYDTITVHWTSDDEFSVVSYELQYTIFTGQANVV 428
Query: 473 AQ-PGPTRWQRREEVRGTSALLENPDTGSVYVLRVRGCNKAGYGEYSEDVHLHTPPAPVL 531
+ W ++ + +G+ Y+ V+ N+AG SE L T P
Sbjct: 429 SLCNSADSWMIVPNIKQNHYTVHGLQSGTKYIFMVKAINQAG-SRSSEPGKLKTNSQP-- 485
Query: 532 HFFLDSRWGASRERLAISKDQRAV-RSVPGLPLLLAADRLLTGCHLSVDVVLGDVAVTQG 590
F LD + ++ +L +S D V R +R + V G+V + G
Sbjct: 486 -FKLDPK--SAHRKLKVSHDNLTVERDESSSKKSHTPERFTSQGSYG---VAGNVFIDSG 539
Query: 591 RSYWACAVDPASYLVKVGVGLESKLQESFQGAPDVISPRYDPDSGHDSGAEDATVEASPP 650
R YW + +++ +G+ +S +P+++
Sbjct: 540 RHYWEVVISGSTWYA-IGLAYKS-------------APKHE------------------- 566
Query: 651 FAFLTIGMGKILLGSGASSNAGLTGRDGPTAGCTVPLPP-----RLGICLDYERGRVSFL 705
IG +N + + +P+ P R+GI LDY+ G ++F
Sbjct: 567 ----WIGKNSASWALCRCNNNWVVRHNSK----EIPIEPAPHLRRVGILLDYDNGSIAFY 618
Query: 706 DAVSFRGLLECPLDCSGPVCPAF 728
DA++ L + + PVCP F
Sbjct: 619 DALNSIHLYTFDVAFAQPVCPTF 641
>gi|223890259 midline 2 isoform 2 [Homo sapiens]
Length = 705
Score = 205 bits (522), Expect = 1e-52
Identities = 176/742 (23%), Positives = 306/742 (41%), Gaps = 132/742 (17%)
Query: 21 STSMKNMEKELLCPVCQEMYKQPLVLPCTHNVCQACAREVLGQQGYIGHGGDPSSEPTSP 80
S M+ +E EL CP+C E+++ PL+LPC H++C +CA +L G +P
Sbjct: 18 SLKMETLESELTCPICLELFEDPLLLPCAHSLCFSCAHRILVSSCSSGESIEP------- 70
Query: 81 ASTPSTRSPRLSRRTLPKPDRLDRLLKSGFGTYPGRKRGALHPQVIMFPCPACQGDVELG 140
+ F CP C+ + L
Sbjct: 71 --------------------------------------------ITAFQCPTCRYVISLN 86
Query: 141 ERGLAGLFRNLTLERVVERYRQSVSVGGA----------------------ILCQLCKP- 177
RGL GL RN+TL+ +++R+ Q SV G I CQ C+
Sbjct: 87 HRGLDGLKRNVTLQNIIDRF-QKASVSGPNSPSESRRERTYRPTTAMSSERIACQFCEQD 145
Query: 178 PPLEATKGCTECRATFCNECFKLFHPWGTQKAQHEPTLPTLSFRPKGLMCPDHK-EEVTH 236
PP +A K C C ++C+ C + HP H P +G+ C DH+ E+V
Sbjct: 146 PPRDAVKTCITCEVSYCDRCLRATHPNKKPFTSHRLVEPVPDTHLRGITCLDHENEKVNM 205
Query: 237 YCKTCQRLVCQLCRVRRTHSGHKITPVLSAYQALKDKLTKSLTYILGNQDTVQTQICELE 296
YC + +L+C LC++ H H++ + ++ LK L +LT ++ ++ Q+ +L
Sbjct: 206 YCVSDDQLICALCKLVGRHRDHQVASLNDRFEKLKQTLEMNLTNLVKRNSELENQMAKLI 265
Query: 297 EAVRHTEVSGQQAKEEVSQLVRGLGAVLEEKRASLLQAIEECQQERLARLSAQIQEHRSL 356
+ + EV+ + ++ + L ++++++ + I+E + +L +L+ Q+ R
Sbjct: 266 QICQQVEVNTAMHEAKLMEECDELVEIIQQRKQMIAVKIKETKVMKLRKLAQQVANCRQC 325
Query: 357 LDGSG-LVGYAQEVLKETDQPCFVQAAKQLHNRIARATEALQTFRPAA--SSSFRHCQLD 413
L+ S L+ A+ +LKE DQ F+Q+AK + R+A AT + Q P + +F + LD
Sbjct: 326 LERSTVLINQAEHILKENDQARFLQSAKNIAERVAMATASSQVLIPDINFNDAFENFALD 385
Query: 414 VGREMKLLTELNFLRVPEAPVIDTQR-TFAYDQIFLCWRLPPH---SPPAWHYTVEFRRT 469
RE KLL L++L P P I + T ++D I + W S YT+ +
Sbjct: 386 FSREKKLLEGLDYLTAPNPPSIREELCTASHDTITVHWISDDEFSISSYELQYTIFTGQA 445
Query: 470 D-VPAQPGPTRWQRREEVRGTSALLENPDTGSVYVLRVRGCNKAGYGEYSEDVHLHTPPA 528
+ + W ++ + +G+ Y+ V+ N+AG SE L T
Sbjct: 446 NFISLYNSVDSWMIVPNIKQNHYTVHGLQSGTRYIFIVKAINQAG-SRNSEPTRLKTNSQ 504
Query: 529 PVLHFFLDSRWGASRERLAISKD-QRAVRSVPGLPLLLAADRLL-TGCHLSVDVVLGDVA 586
P F LD + + ++L IS D + + L +R TGC+ + G++
Sbjct: 505 P---FKLDPK--MTHKKLKISNDGLQMEKDESSLKKSHTPERFSGTGCYGAA----GNIF 555
Query: 587 VTQGRSYWACAVDPASYLVKVGVGLESKLQESFQGAPDVISPRYDPDSGHDSGAEDATVE 646
+ G YW + +++ +G+ +S + + G +
Sbjct: 556 IDSGCHYWEVVMGSSTWYA-IGIAYKSAPKNEWIG------------------------K 590
Query: 647 ASPPFAFLTIGMGKILLGSGASSNAGLTGRDGPTAGCTVPLPPRLGICLDYERGRVSFLD 706
+ + F S +SN + + P RLG+ LDY+ +SF D
Sbjct: 591 NASSWVF-----------SRCNSNFVVRHNNKEMLVDVPPHLKRLGVLLDYDNNMLSFYD 639
Query: 707 AVSFRGLLECPLDCSGPVCPAF 728
+ L + PVCP F
Sbjct: 640 PANSLHLHTFDVTFILPVCPTF 661
>gi|223890257 midline 2 isoform 1 [Homo sapiens]
Length = 735
Score = 196 bits (499), Expect = 5e-50
Identities = 179/772 (23%), Positives = 307/772 (39%), Gaps = 162/772 (20%)
Query: 21 STSMKNMEKELLCPVCQEMYKQPLVLPCTHNVCQACAREVLGQQGYIGHGGDPSSEPTSP 80
S M+ +E EL CP+C E+++ PL+LPC H++C +CA +L G +P
Sbjct: 18 SLKMETLESELTCPICLELFEDPLLLPCAHSLCFSCAHRILVSSCSSGESIEP------- 70
Query: 81 ASTPSTRSPRLSRRTLPKPDRLDRLLKSGFGTYPGRKRGALHPQVIMFPCPACQGDVELG 140
+ F CP C+ + L
Sbjct: 71 --------------------------------------------ITAFQCPTCRYVISLN 86
Query: 141 ERGLAGLFRNLTLERVVERYRQSVSVGGA----------------------ILCQLCKP- 177
RGL GL RN+TL+ +++R+ Q SV G I CQ C+
Sbjct: 87 HRGLDGLKRNVTLQNIIDRF-QKASVSGPNSPSESRRERTYRPTTAMSSERIACQFCEQD 145
Query: 178 PPLEATKGCTECRATFCNECFKLFHPWGTQKAQHEPTLPTLSFRPKGLMCPDHK-EEVTH 236
PP +A K C C ++C+ C + HP H P +G+ C DH+ E+V
Sbjct: 146 PPRDAVKTCITCEVSYCDRCLRATHPNKKPFTSHRLVEPVPDTHLRGITCLDHENEKVNM 205
Query: 237 YCKTCQRLVCQLCRVRRTHSGHKITPVLSAYQALKDKLTKSLTYILGNQDTVQTQICELE 296
YC + +L+C LC++ H H++ + ++ LK L +LT ++ ++ Q+ +L
Sbjct: 206 YCVSDDQLICALCKLVGRHRDHQVASLNDRFEKLKQTLEMNLTNLVKRNSELENQMAKLI 265
Query: 297 EAVRHTEVSGQQAKEEVSQLVRGLGAVLEEKRASLLQAIEECQQERLARLSAQIQEHRSL 356
+ + EV+ + ++ + L ++++++ + I+E + +L +L+ Q+ R
Sbjct: 266 QICQQVEVNTAMHEAKLMEECDELVEIIQQRKQMIAVKIKETKVMKLRKLAQQVANCRQC 325
Query: 357 LDGSG-LVGYAQEVLKETDQPCFVQAAKQLHNRIARATEALQTFRPAA--SSSFRHCQLD 413
L+ S L+ A+ +LKE DQ F+Q+AK + R+A AT + Q P + +F + LD
Sbjct: 326 LERSTVLINQAEHILKENDQARFLQSAKNIAERVAMATASSQVLIPDINFNDAFENFALD 385
Query: 414 VGREMKLLTELNFLRVPEAPVIDTQR-TFAYDQIFLCW---------------------- 450
RE KLL L++L P P I + T ++D I + W
Sbjct: 386 FSREKKLLEGLDYLTAPNPPSIREELCTASHDTITVHWISDDEFSISSYELQYTIFTGQA 445
Query: 451 RLPPHSPPAWHYTVEFRR----TDVPAQPGPTR--------WQRREEVRGTSALLENPDT 498
S +W E R+ G R W ++ + +
Sbjct: 446 NFISKSWCSWGLWPEIRKCKEAVSCSRLAGAPRGLYNSVDSWMIVPNIKQNHYTVHGLQS 505
Query: 499 GSVYVLRVRGCNKAGYGEYSEDVHLHTPPAPVLHFFLDSRWGASRERLAISKD-QRAVRS 557
G+ Y+ V+ N+AG SE L T P F LD + + ++L IS D + +
Sbjct: 506 GTRYIFIVKAINQAG-SRNSEPTRLKTNSQP---FKLDPK--MTHKKLKISNDGLQMEKD 559
Query: 558 VPGLPLLLAADRLL-TGCHLSVDVVLGDVAVTQGRSYWACAVDPASYLVKVGVGLESKLQ 616
L +R TGC+ + G++ + G YW + +++ +G+ +S +
Sbjct: 560 ESSLKKSHTPERFSGTGCYGAA----GNIFIDSGCHYWEVVMGSSTWYA-IGIAYKSAPK 614
Query: 617 ESFQGAPDVISPRYDPDSGHDSGAEDATVEASPPFAFLTIGMGKILLGSGASSNAGLTGR 676
+ G + + + F S +SN +
Sbjct: 615 NEWIG------------------------KNASSWVF-----------SRCNSNFVVRHN 639
Query: 677 DGPTAGCTVPLPPRLGICLDYERGRVSFLDAVSFRGLLECPLDCSGPVCPAF 728
+ P RLG+ LDY+ +SF D + L + PVCP F
Sbjct: 640 NKEMLVDVPPHLKRLGVLLDYDNNMLSFYDPANSLHLHTFDVTFILPVCPTF 691
>gi|190341104 tripartite motif protein 9 isoform 1 [Homo sapiens]
Length = 710
Score = 177 bits (449), Expect = 3e-44
Identities = 171/634 (26%), Positives = 264/634 (41%), Gaps = 106/634 (16%)
Query: 24 MKNMEKELLCPVCQEMYKQPLVLPCTHNVCQACAREVLGQQGYIGHGGDPSSEPTSPAST 83
M+ ME+EL CPVC Y++P++LPC+HN+CQACAR +L Q P SE
Sbjct: 1 MEEMEEELKCPVCGSFYREPIILPCSHNLCQACARNILVQ--------TPESE------- 45
Query: 84 PSTRSPRLSRRTLPKPDRLD-------RLLKSGFGTYPGRKRGALHP------QVIMFP- 129
S +S R + + D LD SG+G+Y G P V +FP
Sbjct: 46 -SPQSHRAAGSGVSDYDYLDLDKMSLYSEADSGYGSYGGFASAPTTPCQKSPNGVRVFPP 104
Query: 130 -----------------------CPACQGDVELGERGLAGLFRNLTLERVVERYRQSVSV 166
CP C + L +RGL G +N LE V++RY+QS +
Sbjct: 105 AMPPPATHLSPALAPVPRNSCITCPQCHRSLILDDRGLRGFPKNRVLEGVIDRYQQSKA- 163
Query: 167 GGAILCQLCKPPPLEATKGCTECRATFCNECFKLFHPWGTQKAQHEPTLPT-------LS 219
A+ CQLC+ P EAT C +C +C+ C HP A+H P LS
Sbjct: 164 -AALKCQLCEKAPKEATVMCEQCDVFYCDPCRLRCHPPRGPLAKHRLVPPAQGRVSRRLS 222
Query: 220 FRPKGLMCPDHK-EEVTHYCKTCQRLVCQLCRVRRTHSGHKITPVLSAYQALKDKLTKSL 278
R K C DH+ E + YC C+ VC C HS H++ + + ++ K +L+++L
Sbjct: 223 PR-KVSTCTDHELENHSMYCVQCKMPVCYQCLEEGKHSSHEVKALGAMWKLHKSQLSQAL 281
Query: 279 TYILGNQDTVQTQICELEEAVRHTEVSGQQAKEEVSQLVRGLGAVLEEKRASLLQAIEEC 338
+ + + +L V+ + + + + + L L ++A LL + +
Sbjct: 282 NGLSDRAKEAKEFLVQLRNMVQQIQENSVEFEACLVAQCDALIDALNRRKAQLLARVNKE 341
Query: 339 QQERLARLSAQIQEHR-SLLDGSGLVGYAQEVLKETDQPCFVQAAKQLHNRIARATE--A 395
+ +L + QI L +GL+ Y EV+KE D F+Q + L R+ +
Sbjct: 342 HEHKLKVVRDQISHCTVKLRQTTGLMEYCLEVIKENDPSGFLQISDALIRRVHLTEDQWG 401
Query: 396 LQTFRPAASSSFRHCQLDVGREMKLLTELNFLR------VPEAPVIDTQRTFAY-DQIFL 448
T P ++ F LD ++ + +L+F++ VP P++ + + + L
Sbjct: 402 KGTLTPRMTTDF-DLSLDNSPLLQSIHQLDFVQVKASSPVPATPILQLEECCTHNNSATL 460
Query: 449 CWRLPPHSP-PAWHYTVEFRRTDVPAQPGPTRWQRREEVRG--TSALLENPDTGSVYVLR 505
W+ PP S PA Y +E Q RE G T ++ S Y R
Sbjct: 461 SWKQPPLSTVPADGYILEL--------DDGNGGQFREVYVGKETMCTVDGLHFNSTYNAR 512
Query: 506 VRGCNKAGYGEYSEDVHLHTPPAPVLHFFLDSRWGASRERLAISKDQRAVRSVPGLPLLL 565
V+ NK G YS+ + L T + V F D G++ + +S D V
Sbjct: 513 VKAFNKTGVSPYSKTLVLQT--SEVAWFAFDP--GSAHSDIILSNDNLTV---------- 558
Query: 566 AADRLLTGCHLSVDVVLGDVAVTQGRSYWACAVD 599
T VVLG ++G YW VD
Sbjct: 559 ------TCSSYDDRVVLGKTGFSKGIHYWELTVD 586
>gi|16519559 tripartite motif protein 9 isoform 2 [Homo sapiens]
Length = 550
Score = 171 bits (434), Expect = 2e-42
Identities = 156/573 (27%), Positives = 243/573 (42%), Gaps = 86/573 (15%)
Query: 24 MKNMEKELLCPVCQEMYKQPLVLPCTHNVCQACAREVLGQQGYIGHGGDPSSEPTSPAST 83
M+ ME+EL CPVC Y++P++LPC+HN+CQACAR +L Q P SE
Sbjct: 1 MEEMEEELKCPVCGSFYREPIILPCSHNLCQACARNILVQ--------TPESE------- 45
Query: 84 PSTRSPRLSRRTLPKPDRLD-------RLLKSGFGTYPGRKRGALHP------QVIMFP- 129
S +S R + + D LD SG+G+Y G P V +FP
Sbjct: 46 -SPQSHRAAGSGVSDYDYLDLDKMSLYSEADSGYGSYGGFASAPTTPCQKSPNGVRVFPP 104
Query: 130 -----------------------CPACQGDVELGERGLAGLFRNLTLERVVERYRQSVSV 166
CP C + L +RGL G +N LE V++RY+QS +
Sbjct: 105 AMPPPATHLSPALAPVPRNSCITCPQCHRSLILDDRGLRGFPKNRVLEGVIDRYQQSKA- 163
Query: 167 GGAILCQLCKPPPLEATKGCTECRATFCNECFKLFHPWGTQKAQHEPTLPT-------LS 219
A+ CQLC+ P EAT C +C +C+ C HP A+H P LS
Sbjct: 164 -AALKCQLCEKAPKEATVMCEQCDVFYCDPCRLRCHPPRGPLAKHRLVPPAQGRVSRRLS 222
Query: 220 FRPKGLMCPDHK-EEVTHYCKTCQRLVCQLCRVRRTHSGHKITPVLSAYQALKDKLTKSL 278
R K C DH+ E + YC C+ VC C HS H++ + + ++ K +L+++L
Sbjct: 223 PR-KVSTCTDHELENHSMYCVQCKMPVCYQCLEEGKHSSHEVKALGAMWKLHKSQLSQAL 281
Query: 279 TYILGNQDTVQTQICELEEAVRHTEVSGQQAKEEVSQLVRGLGAVLEEKRASLLQAIEEC 338
+ + + +L V+ + + + + + L L ++A LL + +
Sbjct: 282 NGLSDRAKEAKEFLVQLRNMVQQIQENSVEFEACLVAQCDALIDALNRRKAQLLARVNKE 341
Query: 339 QQERLARLSAQIQEHR-SLLDGSGLVGYAQEVLKETDQPCFVQAAKQLHNRIARATE--A 395
+ +L + QI L +GL+ Y EV+KE D F+Q + L R+ +
Sbjct: 342 HEHKLKVVRDQISHCTVKLRQTTGLMEYCLEVIKENDPSGFLQISDALIRRVHLTEDQWG 401
Query: 396 LQTFRPAASSSFRHCQLDVGREMKLLTELNFLR------VPEAPVIDTQRTFAY-DQIFL 448
T P ++ F LD ++ + +L+F++ VP P++ + + + L
Sbjct: 402 KGTLTPRMTTDF-DLSLDNSPLLQSIHQLDFVQVKASSPVPATPILQLEECCTHNNSATL 460
Query: 449 CWRLPPHSP-PAWHYTVEFRRTDVPAQPGPTRWQRREEVRG--TSALLENPDTGSVYVLR 505
W+ PP S PA Y +E Q RE G T ++ S Y R
Sbjct: 461 SWKQPPLSTVPADGYILEL--------DDGNGGQFREVYVGKETMCTVDGLHFNSTYNAR 512
Query: 506 VRGCNKAGYGEYSEDVHLHTPPAPVLHFFLDSR 538
V+ NK G YS+ + L T L + R
Sbjct: 513 VKAFNKTGVSPYSKTLVLQTSEGKALQQYPSER 545
>gi|134288906 tripartite motif-containing 67 [Homo sapiens]
Length = 783
Score = 159 bits (402), Expect = 9e-39
Identities = 166/687 (24%), Positives = 265/687 (38%), Gaps = 143/687 (20%)
Query: 27 MEKELLCPVCQEMYKQPLVLPCTHNVCQACAREVL------------------------- 61
ME+EL CPVC ++++P++LPC+HNVC CAR +
Sbjct: 1 MEEELKCPVCGSLFREPIILPCSHNVCLPCARTIAVQTPDGEQHLPQPLLLSRGSGLQAG 60
Query: 62 --------------------------GQQGYIGHGGDPSSEPTSPASTPSTRSPRLSRRT 95
G G G GGD + + + + T S
Sbjct: 61 AAAAASLEHDAAAGPACGGAGGSAAGGLGGGAGGGGDHADKLSLYSETDSGYGSYTPSLK 120
Query: 96 LPKPDRLDRLLKSGFGTYPGRKRGA----LHPQVIMFPCPACQGDVELGERGLAGLFRNL 151
P R+ ++ + G+ RGA L CP C L RGL G RN
Sbjct: 121 SPNGVRVLPMVPAPPGSSAAAARGAACSSLSSSSSSITCPQCHRSASLDHRGLRGFQRNR 180
Query: 152 TLERVVERYRQS------VSVGGAI-LCQLC-KPPPLEATKGCTECRATFCNECFKLFHP 203
LE +V+RY+Q S A+ +CQLC + PP A C +C +C+ C HP
Sbjct: 181 LLEAIVQRYQQGRGAVPGTSAAAAVAICQLCDRTPPEPAATLCEQCDVLYCSACQLKCHP 240
Query: 204 WGTQKAQHEPTLP----------------TLSFRPKG----------------------- 224
A+H P T P G
Sbjct: 241 SRGPFAKHRLVQPPPPPPPPAEAASGPTGTAQGAPSGGGGCKSPGGAGAGATGGSTARKF 300
Query: 225 LMCPDHK-EEVTHYCKTCQRLVCQLCRVRRTHSGHKITPVLSAYQALKDKLTKSLTYILG 283
CP+H+ E + YC +C+ VC LC H+ H++ P+ + ++ K +L+++L +
Sbjct: 301 PTCPEHEMENYSMYCVSCRTPVCYLCLEEGRHAKHEVKPLGAMWKQHKAQLSQALNGVSD 360
Query: 284 NQDTVQTQICELEEAVRHTEVSGQQAKEEVSQLVRGLGAVLEEKRASLLQAIEECQQERL 343
+ + +L+ ++ + +G + + L L ++A LL + + ++ +L
Sbjct: 361 KAKEAKEFLVQLKNILQQIQENGLDYEACLVAQCDALVDALTRQKAKLLTKVTKEREHKL 420
Query: 344 ARLSAQIQE-HRSLLDGSGLVGYAQEVLKETDQPCFVQAAKQLHNRIARATE--ALQTFR 400
+ QI L +GL+ Y EV+KE D F+Q + L R+ + E
Sbjct: 421 KMVWDQINHCTLKLRQSTGLMEYCLEVIKENDPSGFLQISDALIKRVQVSQEQWVKGALE 480
Query: 401 PAASSSFRHCQLDVGREMKLLTELNFL----RVPEAPVIDTQRTFA-YDQIFLCWRLPPH 455
P S+ F LD ++ + +L+F+ RVP P++ ++ + + L WR+PP
Sbjct: 481 PKVSAEF-DLTLDSEPLLQAIHQLDFIQMKCRVPPVPLLQLEKCCTRNNSVTLAWRMPPF 539
Query: 456 SPPAWHYTVEFRRTDVPAQPGPTRWQRREEVRGTSAL--LENPDTGSVYVLRVRGCNKAG 513
+ H V+ ++ G Q RE G L ++ S Y RV+ N +G
Sbjct: 540 T----HSPVDGYILELDDGAG---GQFREVYVGKETLCTIDGLHFNSTYNARVKAFNSSG 592
Query: 514 YGEYSEDVHLHTPPAPVLHFFLDSRWGASRERLAISKDQRAVRSVPGLPLLLAADRLLTG 573
G YS+ V L T + V F D G ++L+ D
Sbjct: 593 VGPYSKTVVLQT--SDVAWFTFDPNSGHR-------------------DIILSNDNQTAT 631
Query: 574 CHLSVD-VVLGDVAVTQGRSYWACAVD 599
C D VVLG A ++G YW VD
Sbjct: 632 CSSYDDRVVLGTAAFSKGVHYWELHVD 658
>gi|19924163 muscle specific ring finger protein 1 [Homo sapiens]
Length = 353
Score = 150 bits (379), Expect = 4e-36
Identities = 109/385 (28%), Positives = 175/385 (45%), Gaps = 99/385 (25%)
Query: 16 ALVRISTSMKNMEKELLCPVCQEMYKQPLV-LPCTHNVCQACAREVLGQQGYIGHGGDPS 74
+L++ M+N+EK+L+CP+C EM+ +P+V LPC HN+C+ CA ++
Sbjct: 6 SLIQDGNPMENLEKQLICPICLEMFTKPVVILPCQHNLCRKCANDIF------------- 52
Query: 75 SEPTSPASTPSTRSPRLSRRTLPKPDRLDRLLKSGFGTYPGRKRGALHPQVIMFPCPACQ 134
+ +P T S +S GR F CP C+
Sbjct: 53 -QAANPYWTSRGSSVSMSG---------------------GR-----------FRCPTCR 79
Query: 135 GDVELGERGLAGLFRNLTLERVVERYRQSVSVGGAILCQLCKPPPLEATKGCTECRATFC 194
+V + G+ GL RNL +E +++ Y+Q C PL
Sbjct: 80 HEVIMDRHGVYGLQRNLLVENIIDIYKQE-----------CSSRPL-------------- 114
Query: 195 NECFKLFHPWGTQKAQHEPTLPTLSFRPKGLMCPDHKEE-VTHYCKTCQRLVCQLCRVRR 253
QK H MC +H++E + YC TC+ C +C+V
Sbjct: 115 ------------QKGSHP-------------MCKEHEDEKINIYCLTCEVPTCSMCKVFG 149
Query: 254 THSGHKITPVLSAYQALKDKLTKSLTYILGNQDTVQTQICELEEAVRHTEVSGQQAKEEV 313
H ++ P+ S +Q K +L ++ ++ D VQT I +LE++ R T+ + Q KEE+
Sbjct: 150 IHKACEVAPLQSVFQGQKTELNNCISMLVAGNDRVQTIITQLEDSRRVTKENSHQVKEEL 209
Query: 314 SQLVRGLGAVLEEKRASLLQAIEECQQERLARLSAQIQEHRSLLDGS-GLVGYAQEVLKE 372
SQ L A+L+EK++ LLQ I + Q+++L+ + A IQ+++ LD S LV A + L E
Sbjct: 210 SQKFDTLYAILDEKKSELLQRITQEQEKKLSFIEALIQQYQEQLDKSTKLVETAIQSLDE 269
Query: 373 TDQPCFVQAAKQLHNRIARATEALQ 397
F+ AKQL I A++ Q
Sbjct: 270 PGGATFLLTAKQLIKSIVEASKGCQ 294
>gi|78482626 ring finger protein 30 isoform 2 [Homo sapiens]
Length = 358
Score = 145 bits (365), Expect = 2e-34
Identities = 108/395 (27%), Positives = 178/395 (45%), Gaps = 98/395 (24%)
Query: 10 FTSIMDALVRISTSMKNMEKELLCPVCQEMYKQPLV-LPCTHNVCQACAREVLGQQGYIG 68
FT L+ + SM N+EK+L+CP+C EM+ +P+V LPC HN+C+ CA +V
Sbjct: 3 FTVGFKPLLGDAHSMDNLEKQLICPICLEMFSKPVVILPCQHNLCRKCANDVF------- 55
Query: 69 HGGDPSSEPTSPASTPSTRSPRLSRRTLPKPDRLDRLLKSGFGTYPGRKRGALHPQVIMF 128
AS P +S R + SG GR F
Sbjct: 56 -----------QASNPLWQS------------RGSTTVSSG-----GR-----------F 76
Query: 129 PCPACQGDVELGERGLAGLFRNLTLERVVERYRQSVSVGGAILCQLCKPPPLEATKGCTE 188
CP+C+ +V L G+ GL RNL +E +++ Y+Q S
Sbjct: 77 RCPSCRHEVVLDRHGVYGLQRNLLVENIIDIYKQESS----------------------- 113
Query: 189 CRATFCNECFKLFHPWGTQKAQHEPTLPTLSFRPKGLMCPDHKEE-VTHYCKTCQRLVCQ 247
P ++ QH LMC +H+EE + YC +C+ C
Sbjct: 114 -------------RPLHSKAEQH-------------LMCEEHEEEKINIYCLSCEVPTCS 147
Query: 248 LCRVRRTHSGHKITPVLSAYQALKDKLTKSLTYILGNQDTVQTQICELEEAVRHTEVSGQ 307
LC+V H ++ P+ + Y+ K +L+ + ++ D VQ I ++EE + E + +
Sbjct: 148 LCKVFGAHKDCEVAPLPTIYKRQKSELSDGIAMLVAGNDRVQAVITQMEEVCQTIEDNSR 207
Query: 308 QAKEEVSQLVRGLGAVLEEKRASLLQAIEECQQERLARLSAQIQEHRSLLDGSG-LVGYA 366
+ K+ ++Q L AVLEE++ LLQA+ Q+E+L R+ I+++ L+ S LV A
Sbjct: 208 RQKQLLNQRFESLCAVLEERKGELLQALAREQEEKLQRVRGLIRQYGDHLEASSKLVESA 267
Query: 367 QEVLKETDQPCFVQAAKQLHNRIARATEALQTFRP 401
+ ++E ++Q AK+L N++ ++ RP
Sbjct: 268 IQSMEEPQMALYLQQAKELINKVGAMSKVELAGRP 302
>gi|34878844 tripartite motif-containing 55 isoform 3 [Homo sapiens]
Length = 452
Score = 143 bits (361), Expect = 5e-34
Identities = 108/413 (26%), Positives = 185/413 (44%), Gaps = 101/413 (24%)
Query: 23 SMKNMEKELLCPVCQEMYKQPLV-LPCTHNVCQACAREVLGQQGYIGHGGDPSSEPTSPA 81
+M N+EK+L+CP+C EM+ +P+V LPC HN+C+ CA ++ A
Sbjct: 16 TMDNLEKQLICPICLEMFTKPVVILPCQHNLCRKCASDIF------------------QA 57
Query: 82 STPSTRSPRLSRRTLPKPDRLDRLLKSGFGTYPGRKRGALHPQVIMFPCPACQGDVELGE 141
S P P R + SG GR F CP+C+ +V L
Sbjct: 58 SNPYL------------PTRGGTTMASG-----GR-----------FRCPSCRHEVVLDR 89
Query: 142 RGLAGLFRNLTLERVVERYRQSVSVGGAILCQLCKPPPLEATKGCTECRATFCNECFKLF 201
G+ GL RNL +E +++ Y+Q E+T+
Sbjct: 90 HGVYGLQRNLLVENIIDIYKQ------------------ESTR----------------- 114
Query: 202 HPWGTQKAQHEPTLPTLSFRPKGLMCPDHKEE-VTHYCKTCQRLVCQLCRVRRTHSGHKI 260
+K +P MC +H+EE + YC C+ C LC+V H ++
Sbjct: 115 ----PEKKSDQP------------MCEEHEEERINIYCLNCEVPTCSLCKVFGAHKDCQV 158
Query: 261 TPVLSAYQALKDKLTKSLTYILGNQDTVQTQICELEEAVRHTEVSGQQAKEEVSQLVRGL 320
P+ +Q K +L+ + ++G+ D VQ I +LE+ + E ++ K+E+ + L
Sbjct: 159 APLTHVFQRQKSELSDGIAILVGSNDRVQGVISQLEDTCKTIEECCRKQKQELCEKFDYL 218
Query: 321 GAVLEEKRASLLQAIEECQQERLARLSAQIQEHRSLLDG-SGLVGYAQEVLKETDQPCFV 379
+LEE++ + Q I Q+E+L + A I+++ L+ S LV + + E + F+
Sbjct: 219 YGILEERKNEMTQVITRTQEEKLEHVRALIKKYSDHLENVSKLVESGIQFMDEPEMAVFL 278
Query: 380 QAAKQLHNRIARATEALQTFR-PAASSSFRHCQLDVGREMKLLTELNFLRVPE 431
Q AK L +I+ A++A Q + + H +++ RE K++ E++F R E
Sbjct: 279 QNAKTLLKKISEASKAFQMEKIEHGYENMNHFTVNLNREEKIIREIDFYREDE 331
>gi|34878836 tripartite motif-containing 55 isoform 1 [Homo sapiens]
Length = 548
Score = 143 bits (361), Expect = 5e-34
Identities = 108/413 (26%), Positives = 185/413 (44%), Gaps = 101/413 (24%)
Query: 23 SMKNMEKELLCPVCQEMYKQPLV-LPCTHNVCQACAREVLGQQGYIGHGGDPSSEPTSPA 81
+M N+EK+L+CP+C EM+ +P+V LPC HN+C+ CA ++ A
Sbjct: 16 TMDNLEKQLICPICLEMFTKPVVILPCQHNLCRKCASDIF------------------QA 57
Query: 82 STPSTRSPRLSRRTLPKPDRLDRLLKSGFGTYPGRKRGALHPQVIMFPCPACQGDVELGE 141
S P P R + SG GR F CP+C+ +V L
Sbjct: 58 SNPYL------------PTRGGTTMASG-----GR-----------FRCPSCRHEVVLDR 89
Query: 142 RGLAGLFRNLTLERVVERYRQSVSVGGAILCQLCKPPPLEATKGCTECRATFCNECFKLF 201
G+ GL RNL +E +++ Y+Q E+T+
Sbjct: 90 HGVYGLQRNLLVENIIDIYKQ------------------ESTR----------------- 114
Query: 202 HPWGTQKAQHEPTLPTLSFRPKGLMCPDHKEE-VTHYCKTCQRLVCQLCRVRRTHSGHKI 260
+K +P MC +H+EE + YC C+ C LC+V H ++
Sbjct: 115 ----PEKKSDQP------------MCEEHEEERINIYCLNCEVPTCSLCKVFGAHKDCQV 158
Query: 261 TPVLSAYQALKDKLTKSLTYILGNQDTVQTQICELEEAVRHTEVSGQQAKEEVSQLVRGL 320
P+ +Q K +L+ + ++G+ D VQ I +LE+ + E ++ K+E+ + L
Sbjct: 159 APLTHVFQRQKSELSDGIAILVGSNDRVQGVISQLEDTCKTIEECCRKQKQELCEKFDYL 218
Query: 321 GAVLEEKRASLLQAIEECQQERLARLSAQIQEHRSLLDG-SGLVGYAQEVLKETDQPCFV 379
+LEE++ + Q I Q+E+L + A I+++ L+ S LV + + E + F+
Sbjct: 219 YGILEERKNEMTQVITRTQEEKLEHVRALIKKYSDHLENVSKLVESGIQFMDEPEMAVFL 278
Query: 380 QAAKQLHNRIARATEALQTFR-PAASSSFRHCQLDVGREMKLLTELNFLRVPE 431
Q AK L +I+ A++A Q + + H +++ RE K++ E++F R E
Sbjct: 279 QNAKTLLKKISEASKAFQMEKIEHGYENMNHFTVNLNREEKIIREIDFYREDE 331
>gi|34878821 tripartite motif-containing 55 isoform 2 [Homo sapiens]
Length = 540
Score = 143 bits (361), Expect = 5e-34
Identities = 108/413 (26%), Positives = 185/413 (44%), Gaps = 101/413 (24%)
Query: 23 SMKNMEKELLCPVCQEMYKQPLV-LPCTHNVCQACAREVLGQQGYIGHGGDPSSEPTSPA 81
+M N+EK+L+CP+C EM+ +P+V LPC HN+C+ CA ++ A
Sbjct: 16 TMDNLEKQLICPICLEMFTKPVVILPCQHNLCRKCASDIF------------------QA 57
Query: 82 STPSTRSPRLSRRTLPKPDRLDRLLKSGFGTYPGRKRGALHPQVIMFPCPACQGDVELGE 141
S P P R + SG GR F CP+C+ +V L
Sbjct: 58 SNPYL------------PTRGGTTMASG-----GR-----------FRCPSCRHEVVLDR 89
Query: 142 RGLAGLFRNLTLERVVERYRQSVSVGGAILCQLCKPPPLEATKGCTECRATFCNECFKLF 201
G+ GL RNL +E +++ Y+Q E+T+
Sbjct: 90 HGVYGLQRNLLVENIIDIYKQ------------------ESTR----------------- 114
Query: 202 HPWGTQKAQHEPTLPTLSFRPKGLMCPDHKEE-VTHYCKTCQRLVCQLCRVRRTHSGHKI 260
+K +P MC +H+EE + YC C+ C LC+V H ++
Sbjct: 115 ----PEKKSDQP------------MCEEHEEERINIYCLNCEVPTCSLCKVFGAHKDCQV 158
Query: 261 TPVLSAYQALKDKLTKSLTYILGNQDTVQTQICELEEAVRHTEVSGQQAKEEVSQLVRGL 320
P+ +Q K +L+ + ++G+ D VQ I +LE+ + E ++ K+E+ + L
Sbjct: 159 APLTHVFQRQKSELSDGIAILVGSNDRVQGVISQLEDTCKTIEECCRKQKQELCEKFDYL 218
Query: 321 GAVLEEKRASLLQAIEECQQERLARLSAQIQEHRSLLDG-SGLVGYAQEVLKETDQPCFV 379
+LEE++ + Q I Q+E+L + A I+++ L+ S LV + + E + F+
Sbjct: 219 YGILEERKNEMTQVITRTQEEKLEHVRALIKKYSDHLENVSKLVESGIQFMDEPEMAVFL 278
Query: 380 QAAKQLHNRIARATEALQTFR-PAASSSFRHCQLDVGREMKLLTELNFLRVPE 431
Q AK L +I+ A++A Q + + H +++ RE K++ E++F R E
Sbjct: 279 QNAKTLLKKISEASKAFQMEKIEHGYENMNHFTVNLNREEKIIREIDFYREDE 331
>gi|78482627 ring finger protein 30 isoform 1 [Homo sapiens]
Length = 400
Score = 124 bits (312), Expect = 2e-28
Identities = 108/437 (24%), Positives = 178/437 (40%), Gaps = 140/437 (32%)
Query: 10 FTSIMDALVRISTSMKNMEKELLCPVCQEMYKQPLV-LPCTHNVCQACAREVLGQQGYIG 68
FT L+ + SM N+EK+L+CP+C EM+ +P+V LPC HN+C+ CA +V
Sbjct: 3 FTVGFKPLLGDAHSMDNLEKQLICPICLEMFSKPVVILPCQHNLCRKCANDVF------- 55
Query: 69 HGGDPSSEPTSPASTPSTRSPRLSRRTLPKPDRLDRLLKSGFGTYPGRKRGALHPQVIMF 128
AS P +S R + SG GR F
Sbjct: 56 -----------QASNPLWQS------------RGSTTVSSG-----GR-----------F 76
Query: 129 PCPACQGDVELGERGLAGLFRNLTLERVVERYRQSVSVGGAILCQLCKPPPLEATKGCTE 188
CP+C+ +V L G+ GL RNL +E +++ Y+Q S
Sbjct: 77 RCPSCRHEVVLDRHGVYGLQRNLLVENIIDIYKQESS----------------------- 113
Query: 189 CRATFCNECFKLFHPWGTQKAQHEPTLPTLSFRPKGLMCPDHKEE-VTHYCKTCQRLVCQ 247
P ++ QH LMC +H+EE + YC +C+ C
Sbjct: 114 -------------RPLHSKAEQH-------------LMCEEHEEEKINIYCLSCEVPTCS 147
Query: 248 LCRVRRTHSGHKITPVLSAYQALK------------------------------------ 271
LC+V H ++ P+ + Y+ K
Sbjct: 148 LCKVFGAHKDCEVAPLPTIYKRQKKQDLTLLPRLECSGTNTTYCSLDLPSSSDPPILASQ 207
Query: 272 ------DKLTKSLTYILGNQDTVQTQICELEEAVRHTEVSGQQAKEEVSQLVRGLGAVLE 325
+L+ + ++ D VQ I ++EE + E + ++ K+ ++Q L AVLE
Sbjct: 208 NTKIIDSELSDGIAMLVAGNDRVQAVITQMEEVCQTIEDNSRRQKQLLNQRFESLCAVLE 267
Query: 326 EKRASLLQAIEECQQERLARLSAQIQEHRSLLDGSG-LVGYAQEVLKETDQPCFVQAAKQ 384
E++ LLQA+ Q+E+L R+ I+++ L+ S LV A + ++E ++Q AK+
Sbjct: 268 ERKGELLQALAREQEEKLQRVRGLIRQYGDHLEASSKLVESAIQSMEEPQMALYLQQAKE 327
Query: 385 LHNRIARATEALQTFRP 401
L N++ ++ RP
Sbjct: 328 LINKVGAMSKVELAGRP 344
>gi|89886468 fibronectin type III and SPRY domain containing 1-like
isoform 1 [Homo sapiens]
Length = 498
Score = 119 bits (299), Expect = 8e-27
Identities = 116/497 (23%), Positives = 201/497 (40%), Gaps = 72/497 (14%)
Query: 271 KDKLTKSLTYILGNQDTVQTQICELEEAVRHTEVSGQQAKEEVSQLVRGLGAVLEEKRAS 330
K+ L + ++ + D +Q I L ++ + + E+ + L ++L+E + S
Sbjct: 5 KEALQRIISTLANKNDEIQNFIDTLHHTLKGVQENSSNILSELDEEFDSLYSILDEVKES 64
Query: 331 LLQAIEECQQERLARLSAQIQEHRSLLDGSG-LVGYAQEVLKETDQPCFVQAAKQLHNRI 389
++ I++ Q + L +QI + + L+ S L+ +A L + F +AA+Q+ +R+
Sbjct: 65 MINCIKQEQARKSQELQSQISQCNNALENSEELLEFATRSLDIKEPEEFSKAARQIKDRV 124
Query: 390 ARATEALQTFRPAASSSFRHCQLDVGREMKLLTELNFLRVPEAPVIDTQRTFAYDQ-IFL 448
A+ + +P S + H +D +E ++L L FL VP+AP ID D + +
Sbjct: 125 TMASAFRLSLKPKVSDNMTHLMVDFSQERQMLQTLKFLPVPKAPEIDPVECLVADNSVTV 184
Query: 449 CWRLPPHSPPAWHYTVEFRRTD---VPAQPGPTRWQRREEVRGTSALLENPDTGSVYV-L 504
WR+P H+ +E R+T+ +P W+ + ++GT L S Y+
Sbjct: 185 AWRMPEEDNKIDHFILEHRKTNFDGLPRVKDERCWEIIDNIKGTEYTLSGLKFDSKYMNF 244
Query: 505 RVRGCNKAGYGEYSEDVHLHTPPAPVLHFFLDS--------------RW----GASRERL 546
RVR CNKA GEYS+ V L T L+F LD+ W G +E
Sbjct: 245 RVRACNKAVAGEYSDPVTLET---KALNFNLDNSSSHLNLKVEDTCVEWDPTGGKGQESK 301
Query: 547 AISKDQRAVRSVPG---------LPLLLAADRLLTGCHLSVDVVLGDVAVTQGRSYWACA 597
K+ + P P + + TG VLGD A+ G+ YW
Sbjct: 302 IKGKENKGRSGTPSPKRTSVGSRPPAVRGSRDRFTG---ESYTVLGDTAIESGQHYWEVK 358
Query: 598 VDPASYLVKVGVGLESKLQESFQGAPDVISPRYDPDSGHDSGAEDATVEASPPFAFLTIG 657
VGV ++ G D + + + I
Sbjct: 359 AQKDCKSYSVGVAYKT------------------------LGKFDQLGKTNTSWC---IH 391
Query: 658 MGKILLGSGASSNAGLTGRDGPTAGCTVPLPPRLGICLDYERGRVSFLDAVSFRGLLECP 717
+ L + A+ + + V +P ++G+ D++ G++SF DA S + L
Sbjct: 392 VNNWLQNTFAAKH------NNKVKALDVTVPEKIGVFCDFDGGQLSFYDANSKQLLYSFK 445
Query: 718 LDCSGPVCPAFCFIGGG 734
+ PV P F GG
Sbjct: 446 TKFTQPVLPGFMVWCGG 462
>gi|223718222 fibronectin type III and SPRY domain containing 1-like
isoform 3 [Homo sapiens]
Length = 530
Score = 118 bits (295), Expect = 2e-26
Identities = 115/497 (23%), Positives = 201/497 (40%), Gaps = 72/497 (14%)
Query: 271 KDKLTKSLTYILGNQDTVQTQICELEEAVRHTEVSGQQAKEEVSQLVRGLGAVLEEKRAS 330
++ L + ++ + D +Q I L ++ + + E+ + L ++L+E + S
Sbjct: 37 QEALQRIISTLANKNDEIQNFIDTLHHTLKGVQENSSNILSELDEEFDSLYSILDEVKES 96
Query: 331 LLQAIEECQQERLARLSAQIQEHRSLLDGSG-LVGYAQEVLKETDQPCFVQAAKQLHNRI 389
++ I++ Q + L +QI + + L+ S L+ +A L + F +AA+Q+ +R+
Sbjct: 97 MINCIKQEQARKSQELQSQISQCNNALENSEELLEFATRSLDIKEPEEFSKAARQIKDRV 156
Query: 390 ARATEALQTFRPAASSSFRHCQLDVGREMKLLTELNFLRVPEAPVIDTQRTFAYDQ-IFL 448
A+ + +P S + H +D +E ++L L FL VP+AP ID D + +
Sbjct: 157 TMASAFRLSLKPKVSDNMTHLMVDFSQERQMLQTLKFLPVPKAPEIDPVECLVADNSVTV 216
Query: 449 CWRLPPHSPPAWHYTVEFRRTD---VPAQPGPTRWQRREEVRGTSALLENPDTGSVYV-L 504
WR+P H+ +E R+T+ +P W+ + ++GT L S Y+
Sbjct: 217 AWRMPEEDNKIDHFILEHRKTNFDGLPRVKDERCWEIIDNIKGTEYTLSGLKFDSKYMNF 276
Query: 505 RVRGCNKAGYGEYSEDVHLHTPPAPVLHFFLDS--------------RW----GASRERL 546
RVR CNKA GEYS+ V L T L+F LD+ W G +E
Sbjct: 277 RVRACNKAVAGEYSDPVTLET---KALNFNLDNSSSHLNLKVEDTCVEWDPTGGKGQESK 333
Query: 547 AISKDQRAVRSVPG---------LPLLLAADRLLTGCHLSVDVVLGDVAVTQGRSYWACA 597
K+ + P P + + TG VLGD A+ G+ YW
Sbjct: 334 IKGKENKGRSGTPSPKRTSVGSRPPAVRGSRDRFTG---ESYTVLGDTAIESGQHYWEVK 390
Query: 598 VDPASYLVKVGVGLESKLQESFQGAPDVISPRYDPDSGHDSGAEDATVEASPPFAFLTIG 657
VGV ++ G D + + + I
Sbjct: 391 AQKDCKSYSVGVAYKT------------------------LGKFDQLGKTNTSWC---IH 423
Query: 658 MGKILLGSGASSNAGLTGRDGPTAGCTVPLPPRLGICLDYERGRVSFLDAVSFRGLLECP 717
+ L + A+ + + V +P ++G+ D++ G++SF DA S + L
Sbjct: 424 VNNWLQNTFAAKH------NNKVKALDVTVPEKIGVFCDFDGGQLSFYDANSKQLLYSFK 477
Query: 718 LDCSGPVCPAFCFIGGG 734
+ PV P F GG
Sbjct: 478 TKFTQPVLPGFMVWCGG 494
>gi|13236585 fibronectin type III and SPRY domain containing 1 [Homo
sapiens]
Length = 496
Score = 117 bits (293), Expect = 4e-26
Identities = 102/376 (27%), Positives = 161/376 (42%), Gaps = 36/376 (9%)
Query: 271 KDKLTKSLTYILGNQDTVQTQICELEEAVRHTEVSGQQAKEEVSQLVRGLGAVLEEKRAS 330
++ L K + + + +Q+ I L++ + + E + + +E++ + L ++LEE +
Sbjct: 5 REALRKIIKTLAVKNEEIQSFIYSLKQMLLNVEANSAKVQEDLEAEFQSLFSLLEELKEG 64
Query: 331 LLQAIEECQQERLARLSAQIQE-HRSLLDGSGLVGYAQEVLKETDQPCFVQAAKQLHNRI 389
+L I++ + R L Q+ R+L L+ A + L+ D F QAAKQ+ + +
Sbjct: 65 MLMKIKQDRASRTYELQNQLAACTRALESSEELLETANQTLQAMDSEDFPQAAKQIKDGV 124
Query: 390 ARATEALQTFRPAASSSFRHCQLDVGREMKLLTELNFLRVPEAPVIDTQRTFAYDQ-IFL 448
A + + S + H +D +E ++L L FL VP APVID + D + L
Sbjct: 125 TMAPAFRLSLKAKVSDNMSHLMVDFAQERQMLQALKFLPVPSAPVIDLAESLVADNCVTL 184
Query: 449 CWRLPPHSPPAWHYTVEFRRTDVPAQP---GPTRWQRREEVRGTSALLENPDTGSVYV-L 504
WR+P HY +E+RRT+ P W E +R T L Y+
Sbjct: 185 VWRMPDEDSKIDHYVLEYRRTNFEGPPRLKEDQPWMVIEGIRQTEYTLTGLKFDMKYMNF 244
Query: 505 RVRGCNKAGYGEYSEDVHLHTP------PAPVLHFFL---------DSRWGASRERLAIS 549
RV+ CNKA GE+SE V L TP A H L D+ G ++ A
Sbjct: 245 RVKACNKAVAGEFSEPVTLETPAFMFRLDASTSHQNLRVDDLSVEWDAMGGKVQDIKARE 304
Query: 550 KDQRAVRSVP------GLPLLLAADRLLTG------CHLSVDVVLGDVAVTQGRSYWACA 597
KD + + P G P + R+ +G VLGD + G YW
Sbjct: 305 KDGKGRTASPINSPARGTP---SPKRMPSGRGGRDRFTAESYTVLGDTLIDGGEHYWEVR 361
Query: 598 VDPASYLVKVGVGLES 613
+P S VGV S
Sbjct: 362 YEPDSKAFGVGVAYRS 377
>gi|34878852 tripartite motif-containing 55 isoform 4 [Homo sapiens]
Length = 241
Score = 97.8 bits (242), Expect = 3e-20
Identities = 73/284 (25%), Positives = 118/284 (41%), Gaps = 99/284 (34%)
Query: 23 SMKNMEKELLCPVCQEMYKQPLV-LPCTHNVCQACAREVLGQQGYIGHGGDPSSEPTSPA 81
+M N+EK+L+CP+C EM+ +P+V LPC HN+C+ CA ++ A
Sbjct: 16 TMDNLEKQLICPICLEMFTKPVVILPCQHNLCRKCASDIF------------------QA 57
Query: 82 STPSTRSPRLSRRTLPKPDRLDRLLKSGFGTYPGRKRGALHPQVIMFPCPACQGDVELGE 141
S P P R + SG GR F CP+C+ +V L
Sbjct: 58 SNPYL------------PTRGGTTMASG-----GR-----------FRCPSCRHEVVLDR 89
Query: 142 RGLAGLFRNLTLERVVERYRQSVSVGGAILCQLCKPPPLEATKGCTECRATFCNECFKLF 201
G+ GL RNL +E +++ Y+Q E+T+
Sbjct: 90 HGVYGLQRNLLVENIIDIYKQ------------------ESTR----------------- 114
Query: 202 HPWGTQKAQHEPTLPTLSFRPKGLMCPDHKEE-VTHYCKTCQRLVCQLCRVRRTHSGHKI 260
+K +P MC +H+EE + YC C+ C LC+V H ++
Sbjct: 115 ----PEKKSDQP------------MCEEHEEERINIYCLNCEVPTCSLCKVFGAHKDCQV 158
Query: 261 TPVLSAYQALKDKLTKSLTYILGNQDTVQTQICELEEAVRHTEV 304
P+ +Q K +L+ + ++G+ D VQ I +LE+ + E+
Sbjct: 159 APLTHVFQRQKSELSDGIAILVGSNDRVQGVISQLEDTCKTIEI 202
>gi|28195390 tripartite motif-containing 42 [Homo sapiens]
Length = 723
Score = 87.0 bits (214), Expect = 6e-17
Identities = 67/282 (23%), Positives = 115/282 (40%), Gaps = 16/282 (5%)
Query: 130 CPACQGDVELGERGLAGLFRNLTLERVVERYRQSVSV--------GGAILCQLCKPPPLE 181
CP C + L N R+ +RY Q G ILCQ+C+ +
Sbjct: 188 CPVCDRSHCMPYSNKMQLPENYLHGRLTKRYMQEHGYLKWRFDRSSGPILCQVCRNRRI- 246
Query: 182 ATKGCTECRATFCNECFKLFHPWGTQKAQHEPTLPTLSFRPKGLMCPDH-KEEVTHYCKT 240
A K C CR CN+C K FH Q + T + +C H + YC+
Sbjct: 247 AYKRCITCRLNLCNDCLKAFH--SDVAMQDHVFVDTSAEEQDEKICIHHPSSRIIEYCRN 304
Query: 241 CQRLVCQLCRVRRTHSGHKITPVLSAYQALKDKLTKSLTYILGNQDTVQTQICELEEAVR 300
+L+C C+ H+GH ++ A L ++ + + + E
Sbjct: 305 DNKLLCTFCKFS-FHNGHDTISLIDACSERAASLFSAIAKFKAVRYEIDNDLMEFNILKN 363
Query: 301 HTEVSGQQAKEEVSQLVRGLGAVLEEKRASLLQAIEECQQERLARLSAQIQ-EHRSLLDG 359
+ + ++E+ L ++L+EK +++ IE + R + + + +
Sbjct: 364 SFKADKEAKRKEIRNGFLKLRSILQEKEKIIMEQIENLEVSRQKEIEKYVYVTTMKVNEM 423
Query: 360 SGLVGYAQEVLKETDQPCFVQAAKQLHNRIARATEALQTFRP 401
GL+ Y++E LKET Q F+Q+AK L ++I + T+RP
Sbjct: 424 DGLIAYSKEALKETGQVAFLQSAKILVDQIEDGIQT--TYRP 463
Score = 36.2 bits (82), Expect = 0.12
Identities = 11/35 (31%), Positives = 21/35 (60%)
Query: 26 NMEKELLCPVCQEMYKQPLVLPCTHNVCQACAREV 60
++ L CP+C + +LPC H++C+ C R++
Sbjct: 139 HLVNHLNCPMCSRLRLHSFMLPCNHSLCEKCLRQL 173
>gi|54792146 tripartite motif-containing 47 [Homo sapiens]
Length = 638
Score = 80.9 bits (198), Expect = 4e-15
Identities = 82/335 (24%), Positives = 127/335 (37%), Gaps = 39/335 (11%)
Query: 33 CPVCQEMYKQPLVLPCTHNVCQACAREVLGQQGYIGHGGDPSSEPTSPASTPSTRSPRLS 92
CP+C E ++P+ LPC HN C AC + +G G GG P A P + P
Sbjct: 9 CPICLEPLREPVTLPCGHNFCLACLGALWPHRGASGAGG-----PGGAARCPLCQEPFPD 63
Query: 93 RRTLPKPDRLDRLLKSGFGTYPGRKRGALHPQVIMFPCPACQGDVELGERGLAGLFRNLT 152
L K L LL+ G+ PG G P + P P+ + A
Sbjct: 64 GLQLRKNHTLSELLQLRQGSGPGSGPG---PAPALAPEPSAPSALPSVPEPSAPC----- 115
Query: 153 LERVVERYRQSVSVGGAILCQLC-KPPPLEATKGCTECRATFCNECFKLFHPWGTQKAQH 211
E + + C C + L A C C A+FC P +
Sbjct: 116 ---APEPWPAGEE---PVRCDACPEGAALPAALSCLSCLASFC--------PAHLGPHER 161
Query: 212 EPTL------PTLSFRPKGLMCPDHKEEVTHYCKTCQRLVCQLCRVRRTHSGHKITPVLS 265
P L P L R + +CP H + YC+ + +C+ C + H GH++ P+
Sbjct: 162 SPALRGHRLVPPLR-RLEESLCPRHLRPLERYCRAERVCLCEACAAQE-HRGHELVPLEQ 219
Query: 266 AYQALKDKLTKSLTYILGNQDTVQTQICELEEAVRHTEVSGQQAKEEVSQLVRGLGAVLE 325
+ + +K L+ + D + I + V + + +E VS+L A L+
Sbjct: 220 ERALQEAEQSKVLSAVEDRMDELGAGIAQSRRTVALIKSAAVAERERVSRLFADAAAALQ 279
Query: 326 EKRASLLQAIEECQQERLARLSAQI---QEHRSLL 357
+ +L IEE + L R + +E RS L
Sbjct: 280 GFQTQVLGFIEEGEAAMLGRSQGDLRRQEEQRSRL 314
>gi|224548923 tripartite motif-containing 45 isoform 2 [Homo
sapiens]
Length = 562
Score = 78.2 bits (191), Expect = 3e-14
Identities = 98/398 (24%), Positives = 153/398 (38%), Gaps = 71/398 (17%)
Query: 33 CPVCQEMYKQPLVLPCTHNVCQACAREVLGQQGYIGHGGDPSSEPTSPASTPSTRSPRLS 92
CP+C ++K P +LPC H VC C ++ GGD S+ +S S PR
Sbjct: 29 CPLCLGLFKAPRLLPCLHTVCTTCLEQLEPFSVVDIRGGD--SDTSSEGSIFQELKPRS- 85
Query: 93 RRTLPKPDRLDRLLKSGFGTYPGRKRGALHPQVIMFPCPACQGDVELGERGLAGL-FRNL 151
L+S G CP C V+L G+ L +L
Sbjct: 86 -------------LQSQIGIL----------------CPVCDAQVDLPMGGVKALTIDHL 116
Query: 152 TLERVV-ERYRQSVSVGGAILCQLCKPPPLEATKGCTECRATFCNECFKLFHPWGTQKAQ 210
+ V+ E R G ++C LC +E K C C+A C+ C + + Q
Sbjct: 117 AVNDVMLESLRGE---GQGLVCDLCNDREVE--KRCQTCKANLCHFCCQ------AHRRQ 165
Query: 211 HEPTLPTL---------SFRPKGLMCPDHK-EEVTHYCKTCQRLVCQLCRVRRTHSGHKI 260
+ T T+ S K ++CP H EE+ +C+ C R VCQ C V H H
Sbjct: 166 KKTTYHTMVDLKDLKGYSRIGKPILCPVHPAEELRLFCEFCDRPVCQDCVVGE-HREHPC 224
Query: 261 TPVLSAYQALKDKLTKSLTYILGNQDTVQTQICELEEAVRHTEVSG---QQAKEEVSQLV 317
+ D + + L G Q V+ LEEA+ + Q+ E V+ V
Sbjct: 225 DFTSNVIHKHGDSVWELLK---GTQPHVEA----LEEALAQIHIINSALQKRVEAVAADV 277
Query: 318 R----GLGAVLEEKRASLLQAIEECQQERLARLSAQ-IQEHRSLLDGSGLVGYAQEVLKE 372
R G +EE R LL+ +E+ + ++ L Q Q + L D V + + +L
Sbjct: 278 RTFSEGYIKAIEEHRDKLLKQLEDIRAQKENSLQLQKAQLEQLLADMRTGVEFTEHLLTS 337
Query: 373 TDQPCFVQAAKQLHNRIARATEALQTFRPAASSSFRHC 410
+ + + R+ + + + RP + R C
Sbjct: 338 GSDLEILITKRVVVERLRKLNKVQYSTRPGVNDKIRFC 375
>gi|224548921 tripartite motif-containing 45 isoform 1 [Homo
sapiens]
Length = 580
Score = 78.2 bits (191), Expect = 3e-14
Identities = 98/398 (24%), Positives = 153/398 (38%), Gaps = 71/398 (17%)
Query: 33 CPVCQEMYKQPLVLPCTHNVCQACAREVLGQQGYIGHGGDPSSEPTSPASTPSTRSPRLS 92
CP+C ++K P +LPC H VC C ++ GGD S+ +S S PR
Sbjct: 29 CPLCLGLFKAPRLLPCLHTVCTTCLEQLEPFSVVDIRGGD--SDTSSEGSIFQELKPRS- 85
Query: 93 RRTLPKPDRLDRLLKSGFGTYPGRKRGALHPQVIMFPCPACQGDVELGERGLAGL-FRNL 151
L+S G CP C V+L G+ L +L
Sbjct: 86 -------------LQSQIGIL----------------CPVCDAQVDLPMGGVKALTIDHL 116
Query: 152 TLERVV-ERYRQSVSVGGAILCQLCKPPPLEATKGCTECRATFCNECFKLFHPWGTQKAQ 210
+ V+ E R G ++C LC +E K C C+A C+ C + + Q
Sbjct: 117 AVNDVMLESLRGE---GQGLVCDLCNDREVE--KRCQTCKANLCHFCCQ------AHRRQ 165
Query: 211 HEPTLPTL---------SFRPKGLMCPDHK-EEVTHYCKTCQRLVCQLCRVRRTHSGHKI 260
+ T T+ S K ++CP H EE+ +C+ C R VCQ C V H H
Sbjct: 166 KKTTYHTMVDLKDLKGYSRIGKPILCPVHPAEELRLFCEFCDRPVCQDCVVGE-HREHPC 224
Query: 261 TPVLSAYQALKDKLTKSLTYILGNQDTVQTQICELEEAVRHTEVSG---QQAKEEVSQLV 317
+ D + + L G Q V+ LEEA+ + Q+ E V+ V
Sbjct: 225 DFTSNVIHKHGDSVWELLK---GTQPHVEA----LEEALAQIHIINSALQKRVEAVAADV 277
Query: 318 R----GLGAVLEEKRASLLQAIEECQQERLARLSAQ-IQEHRSLLDGSGLVGYAQEVLKE 372
R G +EE R LL+ +E+ + ++ L Q Q + L D V + + +L
Sbjct: 278 RTFSEGYIKAIEEHRDKLLKQLEDIRAQKENSLQLQKAQLEQLLADMRTGVEFTEHLLTS 337
Query: 373 TDQPCFVQAAKQLHNRIARATEALQTFRPAASSSFRHC 410
+ + + R+ + + + RP + R C
Sbjct: 338 GSDLEILITKRVVVERLRKLNKVQYSTRPGVNDKIRFC 375
>gi|148596968 tripartite motif-containing 8 [Homo sapiens]
Length = 551
Score = 69.7 bits (169), Expect = 9e-12
Identities = 79/360 (21%), Positives = 131/360 (36%), Gaps = 66/360 (18%)
Query: 28 EKELLCPVCQEMYKQPLVLPCTHNVCQACAREVLGQQGYIGHGGDPSSEPTSPASTPSTR 87
E+EL+CP+C ++ +P+ LPC HN C+ C E + + R
Sbjct: 10 EEELICPICLHVFVEPVQLPCKHNFCRGCIGEAWAKDSGL------------------VR 51
Query: 88 SPRLSRRTLPKPDRLDRLLKSGFGTYPGRKRGALHPQVIMFPCPACQGDVELGERGLAGL 147
P ++ KP L++ LK T K ALH VE L +
Sbjct: 52 CPECNQAYNQKPG-LEKNLKL---TNIVEKFNALH--------------VEKPPAALHCV 93
Query: 148 FRNLTLERVVERYRQSVSVGGAILCQLCKPPPLEATKGCTECRATFCNECFKLFHPWGTQ 207
F C+ P P A K C C A C + +
Sbjct: 94 F-----------------------CRRGPPLP--AQKVCLRCEAPCCQSHVQTHLQQPST 128
Query: 208 KAQHEPTLPTLSFRPKGLMCPDHKEEVTHYCKTCQRLVCQ-LCRVRRTHSGHKITPVLSA 266
H L + + CP H ++C+ Q VCQ C H GH + V
Sbjct: 129 ARGH---LLVEADDVRAWSCPQHNAYRLYHCEAEQVAVCQYCCYYSGAHQGHSVCDVEIR 185
Query: 267 YQALKDKLTKSLTYILGNQDTVQTQICELEEAVRHTEVSGQQAKEEVSQLVRGLGAVLEE 326
++ L K + + ++ Q+ +LE R E Q KEEV L +L+E
Sbjct: 186 RNEIRKMLMKQQDRLEEREQDIEDQLYKLESDKRLVEEKVNQLKEEVRLQYEKLHQLLDE 245
Query: 327 KRASLLQAIEECQQERLARLSAQ-IQEHRSLLDGSGLVGYAQEVLKETDQPCFVQAAKQL 385
++ +++ Q + + +AQ + + + L+G Q + +T+ F++ K +
Sbjct: 246 DLRQTVEVLDKAQAKFCSENAAQALHLGERMQEAKKLLGSLQLLFDKTEDVSFMKNTKSV 305
>gi|55741632 fibronectin type III and SPRY domain containing 2 [Homo
sapiens]
Length = 749
Score = 69.3 bits (168), Expect = 1e-11
Identities = 70/314 (22%), Positives = 126/314 (40%), Gaps = 26/314 (8%)
Query: 229 DHKEEVTHYCKTCQRLVCQLCRVRRTHSGHKITPVLSAYQALKDKLTKSLTYILGNQDTV 288
D +E +C TC+ + +V H H++ P+ A ++ KD++ K N +
Sbjct: 171 DEEEAADVFCVTCKTPIRAFQKVFDEHKEHEVIPLNEALESAKDEIHK-------NMYKL 223
Query: 289 QTQICELEEAVRHTE-----------VSGQQAKEEVSQLVRGLGAVLEEKRASLLQAIEE 337
+ QI E+E H E Q + ++++ L EEK +QA+ E
Sbjct: 224 EKQIIEMENFANHLEEVFITVEENFGKQEQNFESHYNEILETLAQKYEEK----IQALGE 279
Query: 338 CQQERLARLSAQIQEHRSLLDGSGLVGYAQEVLKETDQPCFVQAAKQLHNRIARATEALQ 397
++E+L L Q+ LD + E + ++ F++ A + +R+ + +
Sbjct: 280 KKKEKLEALYGQLVSCGENLDTCKELMETIEEMCHEEKVDFIKDAVAMADRLGKFLKTKT 339
Query: 398 TFRPAASSSFRHCQLDVGREMKLLTELNFLRVPEAPVIDTQ--RTFAYDQIFLCWRLPPH 455
+A F LD +L+ +N + P APVI+ Q + + +CW L
Sbjct: 340 DVEISAQPEFEDQTLDFSDVEQLMGSINTIPAPSAPVINPQVPNSATGSSVRVCWSL-YS 398
Query: 456 SPPAWHYTVEFRRTDVPAQPGPTRWQRREEVRGTSALLENPDTGSVYVLRVRGCNKAGYG 515
Y + +R + PG + + V+ T + N + Y V N+AG
Sbjct: 399 DDTVESYQLSYRPVQ-DSSPGTDQAEFTVTVKETYCSVTNLVPNTQYEFWVTAHNRAGPS 457
Query: 516 EYSEDVHLHTPPAP 529
SE T P+P
Sbjct: 458 PSSERAVYMTAPSP 471
Score = 49.3 bits (116), Expect = 1e-05
Identities = 75/287 (26%), Positives = 107/287 (37%), Gaps = 53/287 (18%)
Query: 426 FLRVPEAPVIDTQRTFAYDQ-IFLCWRLPPHSPPAWHYTVEFRRTDVPAQPGPTRWQRRE 484
++ P P+I T+ + ++ + +CW + P YTVE + + P G T E
Sbjct: 465 YMTAPSPPIIKTKEIRSCEEAVLICWE-SGNLNPVDSYTVELTQAESPEASGVT-----E 518
Query: 485 EVRG--TSALLENPDTGSVYVLRVRGCNKAGYGEYSEDVHLHTPPAPVLHFFLDSRWGAS 542
V G T + G Y++ VR N G SE +HT + +F L+
Sbjct: 519 SVVGIPTCESVVQLQPGRSYIIYVRALNMGGPSVRSEPATVHTIGS---YFRLNK--DTC 573
Query: 543 RERLAISKD-QRAVRSVPGLPL--LLAADRLLTGCHLSVDVVLGDVAVTQGRSYWACAVD 599
L IS+D AVRS P L +D T C V+G++ +G YW VD
Sbjct: 574 HPWLTISEDGLTAVRSERRTPARELSPSDTHFTRC----VAVMGNLIPVRGHHYWEVEVD 629
Query: 600 PASYLVKVGVGLESKLQESFQGAPDVISPRYDPDSGHDSGAEDATVEASPPFAFLTIGMG 659
+VGV D D GA + FA
Sbjct: 630 -EHLDYRVGVAFA------------------DVRKQEDLGANCLSWCMRHTFA------- 663
Query: 660 KILLGSGASSNAGLTGRDGPTAGCTVPLPPRLGICLDYERGRVSFLD 706
S L R P TVP P ++GI LDYE ++SF +
Sbjct: 664 -----SSRHKYEFLHNRTTPDIRITVP-PKKIGILLDYEHSKLSFFN 704
>gi|47419911 transcriptional intermediary factor 1 alpha isoform a
[Homo sapiens]
Length = 1050
Score = 68.2 bits (165), Expect = 3e-11
Identities = 81/338 (23%), Positives = 128/338 (37%), Gaps = 63/338 (18%)
Query: 33 CPVCQE--MYKQPLVLPCTHNVCQACAREVLGQQGYIGHGGDPSSEPTSPASTPSTRSPR 90
C VC + + P +LPC H+ CQ C + Q Y+ +P P+ SP
Sbjct: 56 CAVCHQNIQSRAPKLLPCLHSFCQRC---LPAPQRYLMLPAPMLGSAETPPPVPAPGSPV 112
Query: 91 LSRRTLPKPDRLDRLLKSGFGTYPGRKRGALHPQVIMFPCPACQGDVELGERGLAGLFRN 150
S F T QV + CP C E ER + N
Sbjct: 113 SG--------------SSPFAT-----------QVGVIRCPVCSQ--ECAERHIID---N 142
Query: 151 LTLERVVERYRQSVSVGGAILCQLCKPPPLEATKGCTECRATFCNECFKLFHPWGTQK-- 208
++ E +V + C C+ EA C EC C C + K
Sbjct: 143 FFVKDTTEVPSSTVEKSNQV-CTSCEDNA-EANGFCVECVEWLCKTCIRAHQRVKFTKDH 200
Query: 209 --AQHEPTLP----TLSFRPKGLMCPDHK-EEVTHYCKTCQRLVCQLCRVRRTHSGHKIT 261
Q E P S RP + CP HK E++ YC+TC +L C+ C++ H H+
Sbjct: 201 TVRQKEEVSPEAVGVTSQRP--VFCPFHKKEQLKLYCETCDKLTCRDCQLLE-HKEHRYQ 257
Query: 262 PVLSAYQ-------ALKDKLTKSLTYILGNQDTVQTQICELEEAVRHTEVSGQQAKEEVS 314
+ A+Q L KL + YI + +Q +I E+ + + +Q ++++
Sbjct: 258 FIEEAFQNQKVIIDTLITKLMEKTKYIKFTGNQIQNRIIEVNQ-------NQKQVEQDIK 310
Query: 315 QLVRGLGAVLEEKRASLLQAIEECQQERLARLSAQIQE 352
+ L + +K +LL +E ++ +L Q QE
Sbjct: 311 VAIFTLMVEINKKGKALLHQLESLAKDHRMKLMQQQQE 348
>gi|47419909 transcriptional intermediary factor 1 alpha isoform b
[Homo sapiens]
Length = 1016
Score = 68.2 bits (165), Expect = 3e-11
Identities = 81/338 (23%), Positives = 128/338 (37%), Gaps = 63/338 (18%)
Query: 33 CPVCQE--MYKQPLVLPCTHNVCQACAREVLGQQGYIGHGGDPSSEPTSPASTPSTRSPR 90
C VC + + P +LPC H+ CQ C + Q Y+ +P P+ SP
Sbjct: 56 CAVCHQNIQSRAPKLLPCLHSFCQRC---LPAPQRYLMLPAPMLGSAETPPPVPAPGSPV 112
Query: 91 LSRRTLPKPDRLDRLLKSGFGTYPGRKRGALHPQVIMFPCPACQGDVELGERGLAGLFRN 150
S F T QV + CP C E ER + N
Sbjct: 113 SG--------------SSPFAT-----------QVGVIRCPVCSQ--ECAERHIID---N 142
Query: 151 LTLERVVERYRQSVSVGGAILCQLCKPPPLEATKGCTECRATFCNECFKLFHPWGTQK-- 208
++ E +V + C C+ EA C EC C C + K
Sbjct: 143 FFVKDTTEVPSSTVEKSNQV-CTSCEDNA-EANGFCVECVEWLCKTCIRAHQRVKFTKDH 200
Query: 209 --AQHEPTLP----TLSFRPKGLMCPDHK-EEVTHYCKTCQRLVCQLCRVRRTHSGHKIT 261
Q E P S RP + CP HK E++ YC+TC +L C+ C++ H H+
Sbjct: 201 TVRQKEEVSPEAVGVTSQRP--VFCPFHKKEQLKLYCETCDKLTCRDCQLLE-HKEHRYQ 257
Query: 262 PVLSAYQ-------ALKDKLTKSLTYILGNQDTVQTQICELEEAVRHTEVSGQQAKEEVS 314
+ A+Q L KL + YI + +Q +I E+ + + +Q ++++
Sbjct: 258 FIEEAFQNQKVIIDTLITKLMEKTKYIKFTGNQIQNRIIEVNQ-------NQKQVEQDIK 310
Query: 315 QLVRGLGAVLEEKRASLLQAIEECQQERLARLSAQIQE 352
+ L + +K +LL +E ++ +L Q QE
Sbjct: 311 VAIFTLMVEINKKGKALLHQLESLAKDHRMKLMQQQQE 348
>gi|27436877 tripartite motif-containing 59 [Homo sapiens]
Length = 403
Score = 66.2 bits (160), Expect = 1e-10
Identities = 73/313 (23%), Positives = 105/313 (33%), Gaps = 107/313 (34%)
Query: 24 MKNMEKELLCPVCQEMYKQPLVLPCTHNVCQACAREVLGQQGYIGHGGDPSSEPTSPAST 83
M N E+EL CP+C +++ P VLPC+H C+ C
Sbjct: 1 MHNFEEELTCPICYSIFEDPRVLPCSHTFCRNC--------------------------- 33
Query: 84 PSTRSPRLSRRTLPKPDRLDRLLKSGFGTYPGRKRGALHPQVIMFPCPACQGDVELGERG 143
L+ +L++ Y R P I CP C+ E+ G
Sbjct: 34 ------------------LENILQASGNFYIWR------PLRIPLKCPNCRSITEIAPTG 69
Query: 144 LAGLFRNLTLERVVERYRQSVSVGGAILCQLCKPPPLEATKGCTECRATFCNECFKLFHP 203
+ L N L ++E+Y+Q HP
Sbjct: 70 IESLPVNFALRAIIEKYQQE-------------------------------------DHP 92
Query: 204 WGTQKAQHEPTLPTLSFRPKGLMCPDHKEEVTHYCKTCQRLVCQLCRVRRTHSGHKITPV 263
T P +P + C K+ V +C T + H GH I +
Sbjct: 93 -------DIVTCPEHYRQPLNVYCLLDKKLVCGHCLTIGQ-----------HHGHPIDDL 134
Query: 264 LSAYQALKDKLTKSLTYILGNQDTVQTQICE-LEEAVRHTEVSGQQAKEEVSQLVRGLGA 322
SAY KD K L + T T + E L+E H+E Q KE V Q + L
Sbjct: 135 QSAYLKEKDTPQKLLEQLTDTHWTDLTHLIEKLKEQKSHSEKMIQGDKEAVLQYFKELND 194
Query: 323 VLEEKRASLLQAI 335
LE+K+ S L A+
Sbjct: 195 TLEQKKKSFLTAL 207
>gi|149193331 tripartite motif protein 15 [Homo sapiens]
Length = 465
Score = 65.9 bits (159), Expect = 1e-10
Identities = 62/284 (21%), Positives = 106/284 (37%), Gaps = 45/284 (15%)
Query: 172 CQLCKPPPLEATKGCTECRATFCNECFKLFHPWGTQKA-------------QHEPTLPTL 218
C LC P +A C TFC C G Q + Q E + +
Sbjct: 16 CTLCAGPLEDAVT--IPCGHTFCRLCLPALSQMGAQSSGKILLCPLCQEEEQAETPMAPV 73
Query: 219 SFRPKG-LMCPDHKEEVTHYCKTCQRLVCQLCRVRRTHSGHKITPVLSAYQALKDKLTKS 277
P G C +H E++ +C+ +C CR TH H + + A Q +D+L
Sbjct: 74 PLGPLGETYCEEHGEKIYFFCENDAEFLCVFCREGPTHQAHTVGFLDEAIQPYRDRLRSR 133
Query: 278 LTYILGNQDTVQTQICELEEAVRHTEVSGQQAKEEVSQLVRGLGAVLEEKRASLLQAIEE 337
L + +D ++ C+ ++ ++ + K +V L LE++R LL + E
Sbjct: 134 LEALSTERDEIEDVKCQEDQKLQVLLTQIESKKHQVETAFERLQQELEQQRCLLLARLRE 193
Query: 338 CQQ--------------ERLARLSAQIQ--EHRSLLDGSGLVGYAQE----------VLK 371
+Q E + RL AQ++ E + S L+ + V
Sbjct: 194 LEQQIWKERDEYITKVSEEVTRLGAQVKELEEKCQQPASELLQDVRVNQSRCEMKTFVSP 253
Query: 372 ETDQPCFVQAAKQLHNRIARATEALQTFRPAASSSFRHCQLDVG 415
E P V+ + H +I E ++ F + + H ++D G
Sbjct: 254 EAISPDLVKKIRDFHRKILTLPEMMRMF---SENLAHHLEIDSG 294
Database: hs.faa
Posted date: Aug 4, 2009 4:42 PM
Number of letters in database: 18,247,518
Number of sequences in database: 37,866
Lambda K H
0.320 0.136 0.422
Gapped
Lambda K H
0.267 0.0410 0.140
Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Hits to DB: 32,440,825
Number of Sequences: 37866
Number of extensions: 1639389
Number of successful extensions: 7412
Number of sequences better than 10.0: 30
Number of HSP's better than 10.0 without gapping: 206
Number of HSP's successfully gapped in prelim test: 148
Number of HSP's that attempted gapping in prelim test: 6518
Number of HSP's gapped (non-prelim): 945
length of query: 759
length of database: 18,247,518
effective HSP length: 110
effective length of query: 649
effective length of database: 14,082,258
effective search space: 9139385442
effective search space used: 9139385442
T: 11
A: 40
X1: 16 ( 7.4 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 41 (21.8 bits)
S2: 66 (30.0 bits)
Search results were obtained with NCBI BLAST and RefSeq entries.
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Guide to the Human Genome
Copyright © 2010 by Stewart Scherer. All rights reserved.