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Search of human proteins with 47087157
BLASTP 2.2.11 [Jun-05-2005]
Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer,
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997),
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs", Nucleic Acids Res. 25:3389-3402.
Query= gi|47087157 nebulette non-muscle isoform [Homo sapiens]
(270 letters)
Database: hs.faa
37,866 sequences; 18,247,518 total letters
Searching..................................................done
Score E
Sequences producing significant alignments: (bits) Value
gi|47087157 nebulette non-muscle isoform [Homo sapiens] 570 e-163
gi|5453710 LIM and SH3 protein 1 [Homo sapiens] 340 8e-94
gi|5453758 nebulette sarcomeric isoform [Homo sapiens] 201 7e-52
gi|46049092 nebulin-related anchoring protein isoform C [Homo sa... 125 5e-29
gi|46049105 nebulin-related anchoring protein isoform S [Homo sa... 125 5e-29
gi|115527120 nebulin [Homo sapiens] 102 4e-22
gi|155030230 sorbin and SH3 domain containing 3 isoform 1 [Homo ... 63 3e-10
gi|65301112 sorbin and SH3 domain containing 3 isoform 2 [Homo s... 63 3e-10
gi|78000165 sorbin and SH3 domain containing 1 isoform 4 [Homo s... 63 3e-10
gi|78000163 sorbin and SH3 domain containing 1 isoform 3 [Homo s... 63 3e-10
gi|78000171 sorbin and SH3 domain containing 1 isoform 7 [Homo s... 62 5e-10
gi|78000169 sorbin and SH3 domain containing 1 isoform 6 [Homo s... 62 5e-10
gi|78000167 sorbin and SH3 domain containing 1 isoform 5 [Homo s... 62 5e-10
gi|7661700 sorbin and SH3 domain containing 1 isoform 2 [Homo sa... 62 5e-10
gi|78000160 sorbin and SH3 domain containing 1 isoform 1 [Homo s... 62 5e-10
gi|193083145 SH3 domain containing 19 isoform c [Homo sapiens] 60 2e-09
gi|193083143 SH3 domain containing 19 isoform b [Homo sapiens] 60 2e-09
gi|193083141 SH3 domain containing 19 isoform a [Homo sapiens] 60 2e-09
gi|20357552 cortactin isoform a [Homo sapiens] 59 4e-09
gi|20357556 cortactin isoform b [Homo sapiens] 59 4e-09
gi|4503047 cysteine-rich protein 1 (intestinal) [Homo sapiens] 58 1e-08
gi|150010572 SH3 domain containing ring finger 3 [Homo sapiens] 56 4e-08
gi|171906575 drebrin-like isoform c [Homo sapiens] 55 5e-08
gi|21361670 drebrin-like isoform a [Homo sapiens] 55 5e-08
gi|19224660 protein kinase C and casein kinase substrate in neur... 55 6e-08
gi|189083753 cysteine and glycine-rich protein 3 [Homo sapiens] 54 1e-07
gi|4502893 cysteine and glycine-rich protein 3 [Homo sapiens] 54 1e-07
gi|62198235 drebrin-like isoform b [Homo sapiens] 54 1e-07
gi|4503049 cysteine-rich protein 2 [Homo sapiens] 54 1e-07
gi|224586855 sorbin and SH3 domain containing 2 isoform 8 [Homo ... 54 2e-07
>gi|47087157 nebulette non-muscle isoform [Homo sapiens]
Length = 270
Score = 570 bits (1468), Expect = e-163
Identities = 270/270 (100%), Positives = 270/270 (100%)
Query: 1 MNPQCARCGKVVYPTEKVNCLDKYWHKGCFHCEVCKMALNMNNYKGYEKKPYCNAHYPKQ 60
MNPQCARCGKVVYPTEKVNCLDKYWHKGCFHCEVCKMALNMNNYKGYEKKPYCNAHYPKQ
Sbjct: 1 MNPQCARCGKVVYPTEKVNCLDKYWHKGCFHCEVCKMALNMNNYKGYEKKPYCNAHYPKQ 60
Query: 61 SFTTVADTPENLRLKQQSELQSQVKYKRDFEESKGRGFSIVTDTPELQRLKRTQEQISNV 120
SFTTVADTPENLRLKQQSELQSQVKYKRDFEESKGRGFSIVTDTPELQRLKRTQEQISNV
Sbjct: 61 SFTTVADTPENLRLKQQSELQSQVKYKRDFEESKGRGFSIVTDTPELQRLKRTQEQISNV 120
Query: 121 KYHEDFEKTKGRGFTPVVDDPVTERVRKNTQVVSDAAYKGVHPHIVEMDRRPGIIVAPVL 180
KYHEDFEKTKGRGFTPVVDDPVTERVRKNTQVVSDAAYKGVHPHIVEMDRRPGIIVAPVL
Sbjct: 121 KYHEDFEKTKGRGFTPVVDDPVTERVRKNTQVVSDAAYKGVHPHIVEMDRRPGIIVAPVL 180
Query: 181 PGAYQQSHSQGYGYMHQTSVSSMRSMQHSPNLRTYRAMYDYSAQDEDEVSFRDGDYIVNV 240
PGAYQQSHSQGYGYMHQTSVSSMRSMQHSPNLRTYRAMYDYSAQDEDEVSFRDGDYIVNV
Sbjct: 181 PGAYQQSHSQGYGYMHQTSVSSMRSMQHSPNLRTYRAMYDYSAQDEDEVSFRDGDYIVNV 240
Query: 241 QPIDDGWMYGTVQRTGRTGMLPANYIEFVN 270
QPIDDGWMYGTVQRTGRTGMLPANYIEFVN
Sbjct: 241 QPIDDGWMYGTVQRTGRTGMLPANYIEFVN 270
>gi|5453710 LIM and SH3 protein 1 [Homo sapiens]
Length = 261
Score = 340 bits (872), Expect = 8e-94
Identities = 170/277 (61%), Positives = 200/277 (72%), Gaps = 24/277 (8%)
Query: 1 MNPQCARCGKVVYPTEKVNCLDKYWHKGCFHCEVCKMALNMNNYKGYEKKPYCNAHYPKQ 60
MNP CARCGK+VYPTEKVNCLDK+WHK CFHCE CKM LNM NYKGYEKKPYCNAHYPKQ
Sbjct: 1 MNPNCARCGKIVYPTEKVNCLDKFWHKACFHCETCKMTLNMKNYKGYEKKPYCNAHYPKQ 60
Query: 61 SFTTVADTPENLRLKQQSELQSQVKYKRDFEESKGRGFSIVTDTPELQRLKRTQEQISNV 120
SFT VADTPENLRLKQQSELQSQV+YK +FE++KG+GFS+V DTPELQR+K+TQ+QISN+
Sbjct: 61 SFTMVADTPENLRLKQQSELQSQVRYKEEFEKNKGKGFSVVADTPELQRIKKTQDQISNI 120
Query: 121 KYHEDFEKTK-----GRGFTPVVDDPVTERVRKNTQVVSD--AAYKGVHPHIVEMDRRPG 173
KYHE+FEK++ G G P R+++Q S + PH +
Sbjct: 121 KYHEEFEKSRMGPSGGEGMEP---------ERRDSQDGSSYRRPLEQQQPHHIPTS---- 167
Query: 174 IIVAPVLPGAYQQSHSQGY-GYMHQTSVSSMRSMQHSPNLRTYRAMYDYSAQDEDEVSFR 232
APV QQ +Q Y GY + S++ + YRA+YDYSA DEDEVSF+
Sbjct: 168 ---APVYQQPQQQPVAQSYGGYKEPAAPVSIQRSAPGGGGKRYRAVYDYSAADEDEVSFQ 224
Query: 233 DGDYIVNVQPIDDGWMYGTVQRTGRTGMLPANYIEFV 269
DGD IVNVQ IDDGWMYGTV+RTG TGMLPANY+E +
Sbjct: 225 DGDTIVNVQQIDDGWMYGTVERTGDTGMLPANYVEAI 261
>gi|5453758 nebulette sarcomeric isoform [Homo sapiens]
Length = 1014
Score = 201 bits (510), Expect = 7e-52
Identities = 96/100 (96%), Positives = 96/100 (96%)
Query: 171 RPGIIVAPVLPGAYQQSHSQGYGYMHQTSVSSMRSMQHSPNLRTYRAMYDYSAQDEDEVS 230
RP APVLPGAYQQSHSQGYGYMHQTSVSSMRSMQHSPNLRTYRAMYDYSAQDEDEVS
Sbjct: 915 RPSDEGAPVLPGAYQQSHSQGYGYMHQTSVSSMRSMQHSPNLRTYRAMYDYSAQDEDEVS 974
Query: 231 FRDGDYIVNVQPIDDGWMYGTVQRTGRTGMLPANYIEFVN 270
FRDGDYIVNVQPIDDGWMYGTVQRTGRTGMLPANYIEFVN
Sbjct: 975 FRDGDYIVNVQPIDDGWMYGTVQRTGRTGMLPANYIEFVN 1014
Score = 162 bits (410), Expect = 3e-40
Identities = 85/130 (65%), Positives = 99/130 (76%), Gaps = 3/130 (2%)
Query: 49 KKPYCNAHYPKQ--SFTTVADTPENLRLKQQSELQSQVKYKRDFEESKGRGFSIVTDTPE 106
+K N +Y Q TT++ TPE R+K+ E S VKY +D ++ KGR S++ DTP
Sbjct: 711 QKNISNVYYRGQLGRATTLSVTPEMERVKKNQENISSVKYTQDHKQMKGRP-SLILDTPA 769
Query: 107 LQRLKRTQEQISNVKYHEDFEKTKGRGFTPVVDDPVTERVRKNTQVVSDAAYKGVHPHIV 166
++ +K Q IS VKYHEDFEKTKGRGFTPVVDDPVTERVRKNTQVVSDAAYKGVHPHIV
Sbjct: 770 MRHVKEAQNHISMVKYHEDFEKTKGRGFTPVVDDPVTERVRKNTQVVSDAAYKGVHPHIV 829
Query: 167 EMDRRPGIIV 176
EMDRRPGIIV
Sbjct: 830 EMDRRPGIIV 839
Score = 71.6 bits (174), Expect = 7e-13
Identities = 51/137 (37%), Positives = 68/137 (49%), Gaps = 8/137 (5%)
Query: 36 KMALNMNNYKGYEKKPYCNAHYPKQSFTTVADTPENLRLKQQSELQSQVKYKRDFEESKG 95
K A M + K Y+K + D P+ LR K+ SE+ SQ KYK + E+
Sbjct: 512 KKASEMASQKQYKKD--LENEIKGKGMQVSMDIPDILRAKRTSEIYSQRKYKDEAEKMLS 569
Query: 96 RGFSIVTDTPELQRLKRTQEQISNVKYHEDFEKTKGRGFTPVVDDPVTERVRKNTQVVSD 155
+S + DTPE+QR+K TQ+ IS V Y +K G G T V D P ERV+KN Q +S
Sbjct: 570 N-YSTIADTPEIQRIKTTQQNISAVFY----KKEVGAG-TAVKDSPEIERVKKNQQNISS 623
Query: 156 AAYKGVHPHIVEMDRRP 172
YK H + P
Sbjct: 624 VKYKEEIKHATAISDPP 640
Score = 64.7 bits (156), Expect = 8e-11
Identities = 38/98 (38%), Positives = 56/98 (57%), Gaps = 10/98 (10%)
Query: 63 TTVADTPENLRLKQQSELQSQVKYKRDFEESKGRGFSIVTDTPELQRLKRTQEQISNVKY 122
T V D+PE R+K+ + S VKYK + + + + ++D PEL+R+K Q+ ISN++Y
Sbjct: 603 TAVKDSPEIERVKKNQQNISSVKYKEEIKHA-----TAISDPPELKRVKENQKNISNLQY 657
Query: 123 HEDFEKTKGRGFTPVVDDPVTERVRKNTQVVSDAAYKG 160
E K TPV P ERVR+N + +S YKG
Sbjct: 658 KEQNYKA-----TPVSMTPEIERVRRNQEQLSAVKYKG 690
Score = 63.5 bits (153), Expect = 2e-10
Identities = 35/95 (36%), Positives = 54/95 (56%), Gaps = 2/95 (2%)
Query: 67 DTPENLRLKQQSELQSQVKYKRDFE-ESKGRGFSIVTDTPELQRLKRTQEQISNVKYHED 125
DT E K+ +E+ S+ YKRD E E KG+G + TDT ++QR K+ E S +Y +D
Sbjct: 467 DTLEMQHAKKAAEIASEKDYKRDLETEIKGKGMQVSTDTLDVQRAKKASEMASQKQYKKD 526
Query: 126 FE-KTKGRGFTPVVDDPVTERVRKNTQVVSDAAYK 159
E + KG+G +D P R ++ +++ S YK
Sbjct: 527 LENEIKGKGMQVSMDIPDILRAKRTSEIYSQRKYK 561
Score = 59.7 bits (143), Expect = 3e-09
Identities = 36/95 (37%), Positives = 50/95 (52%), Gaps = 1/95 (1%)
Query: 66 ADTPENLRLKQQSELQSQVKYKRDFEESKGRGFSIVTDTPELQRLKRTQEQISNVKYHED 125
AD E+L K + LQSQVKYK ++E++KG+ +TP Q K Q+ S Y ED
Sbjct: 319 ADAVEHLHHKGNAVLQSQVKYKEEYEKNKGKPMLEFVETPSYQASKEAQKMQSEKVYKED 378
Query: 126 FEK-TKGRGFTPVVDDPVTERVRKNTQVVSDAAYK 159
FEK KGR + P V+ T ++ + YK
Sbjct: 379 FEKEIKGRSSLDLDKTPEFLHVKYITNLLREKEYK 413
Score = 55.5 bits (132), Expect = 5e-08
Identities = 31/94 (32%), Positives = 50/94 (53%), Gaps = 2/94 (2%)
Query: 68 TPENLRLKQQSELQSQVKYKRDFE-ESKGRGFSIVTDTPELQRLKRTQEQISNVKYHEDF 126
TPE L +K + L + +YK+D E E KG+G + ++ ++QR KR E S +Y +D
Sbjct: 394 TPEFLHVKYITNLLREKEYKKDLENEIKGKGMELNSEVLDIQRAKRASEMASEKEYKKDL 453
Query: 127 EK-TKGRGFTPVVDDPVTERVRKNTQVVSDAAYK 159
E KG+G D + +K ++ S+ YK
Sbjct: 454 ESIIKGKGMQAGTDTLEMQHAKKAAEIASEKDYK 487
Score = 55.5 bits (132), Expect = 5e-08
Identities = 42/170 (24%), Positives = 80/170 (47%), Gaps = 29/170 (17%)
Query: 63 TTVADTPENLRLKQQSELQSQVKYKRDFEESKGRGFSIVTDTPELQRLKRTQEQISNVKY 122
T ++D PE R+K+ + S ++YK ++ + V+ TPE++R++R QEQ+S VKY
Sbjct: 634 TAISDPPELKRVKENQKNISNLQYKEQNYKA-----TPVSMTPEIERVRRNQEQLSAVKY 688
Query: 123 HEDFEKTKGRGFTPVVDDPVTERVRKNTQVVSDAAYKGVHPHIVEMDRRPGIIVAPVLPG 182
+ ++ T + D P +R ++N + +S+ Y+G ++ R + V P +
Sbjct: 689 KGELQRG-----TAISDPPELKRAKENQKNISNVYYRG------QLGRATTLSVTPEMER 737
Query: 183 A-----------YQQSHSQGYGYMHQTSVSSMRSMQHSPNLRTYRAMYDY 221
Y Q H Q G + + +M+H + + +M Y
Sbjct: 738 VKKNQENISSVKYTQDHKQMKG--RPSLILDTPAMRHVKEAQNHISMVKY 785
Score = 54.7 bits (130), Expect = 8e-08
Identities = 32/89 (35%), Positives = 47/89 (52%), Gaps = 2/89 (2%)
Query: 73 RLKQQSELQSQVKYKRDFEES-KGRGFSIVTDTPELQRLKRTQEQISNVKYHEDFE-KTK 130
R K+ SE+ S+ +YK+D E KG+G TDT E+Q K+ E S Y D E + K
Sbjct: 436 RAKRASEMASEKEYKKDLESIIKGKGMQAGTDTLEMQHAKKAAEIASEKDYKRDLETEIK 495
Query: 131 GRGFTPVVDDPVTERVRKNTQVVSDAAYK 159
G+G D +R +K +++ S YK
Sbjct: 496 GKGMQVSTDTLDVQRAKKASEMASQKQYK 524
Score = 47.0 bits (110), Expect = 2e-05
Identities = 38/172 (22%), Positives = 79/172 (45%), Gaps = 17/172 (9%)
Query: 44 YKGYEKKPYCNAHYPKQSFTTVADTPENLRLKQQSELQSQVKYKRDFEESKG-RGFSIVT 102
YKG K N+ Y + T +++ + ++LQS+V YK+ + +KG ++ +
Sbjct: 89 YKGTIKADLSNSLYKRMPATI-----DSVFAGEVTQLQSEVAYKQKHDAAKGFSDYAHMK 143
Query: 103 DTPELQRLKRTQEQISNVKYHEDFEKTKGRGFTPVVDDPVTERVRKNTQVVSDAAYK--- 159
+ PE++ + SN+ Y +D + T ++ +D P + + ++++S+A YK
Sbjct: 144 EPPEVKHAMEVNKHQSNISYRKDVQDT--HTYSAELDRPDIKMATQISKIISNAEYKKGQ 201
Query: 160 GVHPHIVEMDRRPGIIVAPVLPGAYQQSHSQGYGYMHQTSVSSMRSMQHSPN 211
G+ M++ P +I P A + S + + M+ +H N
Sbjct: 202 GI------MNKEPAVIGRPDFEHAVEASKLSSQIKYKEKFDNEMKDKKHHYN 247
Score = 46.6 bits (109), Expect = 2e-05
Identities = 37/177 (20%), Positives = 74/177 (41%), Gaps = 24/177 (13%)
Query: 62 FTTVADTPENLRLKQQSELQSQVKYKRDFEESKGRGFSIVTDTPELQRLKRTQEQISNVK 121
F + D E ++ ++ + QV YK E+ ++ ++ E IS+++
Sbjct: 6 FEDIKDETEEEKIGEEENEEDQVFYKPVIEDLS------------MELARKCTELISDIR 53
Query: 122 YHEDFEKTKGRGFTPVVDDPVTERVRKNTQVVSDAAYKGVHPHIV--EMDRRPGIIVAPV 179
Y E+F+K+K + T V D P+ V+ +S+A YKG + + +R + V
Sbjct: 54 YKEEFKKSKDK-CTFVTDSPMLNHVKNIGAFISEAKYKGTIKADLSNSLYKRMPATIDSV 112
Query: 180 LPG---------AYQQSHSQGYGYMHQTSVSSMRSMQHSPNLRTYRAMYDYSAQDED 227
G AY+Q H G+ + ++H+ + +++ Y +D
Sbjct: 113 FAGEVTQLQSEVAYKQKHDAAKGFSDYAHMKEPPEVKHAMEVNKHQSNISYRKDVQD 169
Score = 45.1 bits (105), Expect = 7e-05
Identities = 36/114 (31%), Positives = 54/114 (47%), Gaps = 10/114 (8%)
Query: 49 KKPYCNAHYPKQSFTTVADTPENLRLK---QQSELQSQVKYKRDFEESKGRGFSIVTDTP 105
KK N H P V+D P L L + S++ S +YK+ FEE+KG + D
Sbjct: 270 KKDIQNMHDP------VSDLPNLLFLDHVLKASKMLSGREYKKLFEENKGM-YHFDADAV 322
Query: 106 ELQRLKRTQEQISNVKYHEDFEKTKGRGFTPVVDDPVTERVRKNTQVVSDAAYK 159
E K S VKY E++EK KG+ V+ P + ++ ++ S+ YK
Sbjct: 323 EHLHHKGNAVLQSQVKYKEEYEKNKGKPMLEFVETPSYQASKEAQKMQSEKVYK 376
Score = 44.3 bits (103), Expect = 1e-04
Identities = 28/95 (29%), Positives = 48/95 (50%), Gaps = 2/95 (2%)
Query: 67 DTPENLRLKQQSELQSQVKYKRDFE-ESKGRGFSIVTDTPELQRLKRTQEQISNVKYHED 125
+TP K+ ++QS+ YK DFE E KGR + TPE +K + +Y +D
Sbjct: 356 ETPSYQASKEAQKMQSEKVYKEDFEKEIKGRSSLDLDKTPEFLHVKYITNLLREKEYKKD 415
Query: 126 FE-KTKGRGFTPVVDDPVTERVRKNTQVVSDAAYK 159
E + KG+G + +R ++ +++ S+ YK
Sbjct: 416 LENEIKGKGMELNSEVLDIQRAKRASEMASEKEYK 450
Score = 28.9 bits (63), Expect = 4.9
Identities = 31/116 (26%), Positives = 49/116 (42%), Gaps = 14/116 (12%)
Query: 54 NAHYPK-----QSFTTVADTPENLRLKQQSELQSQVKYKRDFE-ESKGRGFSI-VTDTPE 106
NA Y K V P+ + S+L SQ+KYK F+ E K + ++
Sbjct: 194 NAEYKKGQGIMNKEPAVIGRPDFEHAVEASKLSSQIKYKEKFDNEMKDKKHHYNPLESAS 253
Query: 107 LQRLKRTQEQISNVKYHEDFEKTKGRGFTPVVDDP---VTERVRKNTQVVSDAAYK 159
++ + SNVKY +D + PV D P + V K ++++S YK
Sbjct: 254 FRQNQLAATLASNVKYKKDIQNM----HDPVSDLPNLLFLDHVLKASKMLSGREYK 305
>gi|46049092 nebulin-related anchoring protein isoform C [Homo
sapiens]
Length = 1695
Score = 125 bits (313), Expect = 5e-29
Identities = 70/198 (35%), Positives = 103/198 (52%), Gaps = 37/198 (18%)
Query: 1 MNPQ-CARCGKVVYPTEKVNCLDKYWHKGCFHCEVCKMALNMNNYKGYEKKPYCNAHYPK 59
MN Q C+RCG VYP EK++C+D+ WHK CFHCEVCKM L++NN+ ++KKPYC+AH PK
Sbjct: 1 MNVQPCSRCGYGVYPAEKISCIDQIWHKACFHCEVCKMMLSVNNFVSHQKKPYCHAHNPK 60
Query: 60 -QSFTTVADTPENLRLKQQSELQSQVKYKRDFEESK------------------------ 94
+FT+V TP NL ++ E S + + D E+ K
Sbjct: 61 NNTFTSVYHTPLNLNVRTFPEAISGIHDQEDGEQCKSVFHWDMKSKDKEGAPNRQPLANE 120
Query: 95 -------GRGFSI---VTDTPELQRLKRTQEQISNVKYHEDFEKTKGRGFTPVVDDPVTE 144
G G + PE+ R+ ++ + +Y ED+E+ +G+G P + P +
Sbjct: 121 RAYWTGYGEGNAWCPGALPDPEIVRMVEARKSLGE-EYTEDYEQPRGKGSFPAMITPAYQ 179
Query: 145 RVRKNTQVVSDAAYKGVH 162
R +K Q+ S YK H
Sbjct: 180 RAKKANQLASQVEYKRGH 197
Score = 70.1 bits (170), Expect = 2e-12
Identities = 42/125 (33%), Positives = 64/125 (51%), Gaps = 1/125 (0%)
Query: 68 TPENLRLKQQSELQSQVKYKRDFEESKGRGFSIVTDTPELQRLKRTQEQISNVKYHEDFE 127
TP R K+ ++L SQV+YKR +E R FS V DTPEL R K + S+V+Y ED+E
Sbjct: 175 TPAYQRAKKANQLASQVEYKRGHDERISR-FSTVVDTPELLRSKAGAQLQSDVRYTEDYE 233
Query: 128 KTKGRGFTPVVDDPVTERVRKNTQVVSDAAYKGVHPHIVEMDRRPGIIVAPVLPGAYQQS 187
+ +G+G P + P + ++ ++ SD Y + + P I +L
Sbjct: 234 QQRGKGSFPAMITPAYQIAKRANELASDVRYHQQYQKEMRGMAGPAIGAEGILTRECADQ 293
Query: 188 HSQGY 192
+ QGY
Sbjct: 294 YGQGY 298
Score = 65.9 bits (159), Expect = 4e-11
Identities = 49/154 (31%), Positives = 75/154 (48%), Gaps = 10/154 (6%)
Query: 62 FTTVADTPENLRLKQQSELQSQVKYKRDFEESKGRGFSIVTDTPELQRLKRTQEQISNVK 121
F+TV DTPE LR K ++LQS V+Y D+E+ +G+G TP Q KR E S+V+
Sbjct: 204 FSTVVDTPELLRSKAGAQLQSDVRYTEDYEQQRGKGSFPAMITPAYQIAKRANELASDVR 263
Query: 122 YHEDFEKTKGRGFTPVVDDPVTERVRKNTQVVSDAAYKGVHPHIVEMDRRPGIIVAPVLP 181
YH+ ++K + RG P T+ +D +G +P E R G A + P
Sbjct: 264 YHQQYQK-EMRGMA----GPAIGAEGILTRECADQYGQG-YPEEYEEHRGKGSFPAMITP 317
Query: 182 GAYQ---QSHSQGYGYMHQTSVSSMRSMQHSPNL 212
AYQ ++H ++ + M+ H +L
Sbjct: 318 -AYQNAKKAHELASDIKYRQDFNKMKGAAHYHSL 350
Score = 65.5 bits (158), Expect = 5e-11
Identities = 35/91 (38%), Positives = 54/91 (59%), Gaps = 9/91 (9%)
Query: 43 NYKG-YEKKPYCNAHYPKQSFTTVADTPENLRLKQQSELQSQVKYKRDFEESKGRGFSIV 101
NY+ YEK K ++T D P+ ++ K ++L S+VKYK +E++KG+GF +
Sbjct: 476 NYRADYEKN--------KLNYTLPQDVPQLVKAKTNAKLFSEVKYKEGWEKTKGKGFEMK 527
Query: 102 TDTPELQRLKRTQEQISNVKYHEDFEKTKGR 132
D L K + E SN+KY E++EKTKG+
Sbjct: 528 LDAMSLLAAKASGELASNIKYKEEYEKTKGK 558
Score = 62.4 bits (150), Expect = 4e-10
Identities = 32/101 (31%), Positives = 58/101 (57%), Gaps = 1/101 (0%)
Query: 59 KQSFTTVADTPENLRLKQQSELQSQVKYKRDFEESKGRGFSIVTDTPELQRLKRTQEQIS 118
K +++V DTP+ ++ K ++ S V Y+ D+E++K +++ D P+L + K + S
Sbjct: 450 KLKYSSVTDTPQIVQAKINAQQLSHVNYRADYEKNK-LNYTLPQDVPQLVKAKTNAKLFS 508
Query: 119 NVKYHEDFEKTKGRGFTPVVDDPVTERVRKNTQVVSDAAYK 159
VKY E +EKTKG+GF +D + + ++ S+ YK
Sbjct: 509 EVKYKEGWEKTKGKGFEMKLDAMSLLAAKASGELASNIKYK 549
Score = 50.8 bits (120), Expect = 1e-06
Identities = 35/108 (32%), Positives = 49/108 (45%), Gaps = 2/108 (1%)
Query: 59 KQSFTTVADTPENLRLKQQSELQSQVKYKRDFEESKGRGFSIVTDTPELQRLKRTQEQIS 118
K +T AD PE L K + S+ +YK + + + G+ + D Q K + E IS
Sbjct: 967 KHHYTPTADLPEVLLAKLNAMNISETRYKESWSKLRDGGYKLRLDALPFQAAKASGEIIS 1026
Query: 119 NVKYHEDFEKTKGR--GFTPVVDDPVTERVRKNTQVVSDAAYKGVHPH 164
+ KY E FEK KG+ G + DD T + SD YK H
Sbjct: 1027 DYKYKEAFEKMKGQMLGSRSLEDDISLAHSVYATSLQSDVNYKKGFEH 1074
Score = 47.0 bits (110), Expect = 2e-05
Identities = 41/163 (25%), Positives = 68/163 (41%), Gaps = 12/163 (7%)
Query: 27 KGCFHCEVCKMALNMNNYKGYEKKPYCNAHYPKQSFTTVADTPENLRLKQQSELQSQVKY 86
+G + E K A + + K Y ++ + FT+V D+ + K+ ELQS V Y
Sbjct: 663 EGSLNLEQAKKAGQLVSEKNYRQR------VDELKFTSVTDSSQMEHAKKSQELQSGVAY 716
Query: 87 KRDFEESKGRGFSIVTDTPELQRLKRTQEQISNVKYHEDFEKTKGRGFTPVVDDPVTERV 146
K E+S + ++I D P + + +S Y +E K +GF +D
Sbjct: 717 KAGNEQSVHQ-YTISKDEPLFLQARANAANLSEKLYKSSWENQKAKGFELRLDSLTFLAA 775
Query: 147 RKNTQVVSDAAYKGVHPHIVEMDRRPGIIVAPVLPGAYQQSHS 189
+ + S+ YK + R +I A + G Q SHS
Sbjct: 776 KAKRDLASEVKYKEDYER-----SRGKLIGAKDVQGDSQMSHS 813
Score = 45.8 bits (107), Expect = 4e-05
Identities = 25/103 (24%), Positives = 47/103 (45%), Gaps = 2/103 (1%)
Query: 59 KQSFTTVADTPENLRLKQQSELQSQVKYKRDFEESKGRGFSIVTDTPELQRLKRTQEQIS 118
+ +T PE +R K + S +YK + + +G+ + + Q + + + S
Sbjct: 1210 RHEYTMTLGLPEFIRAKTNAANLSDARYKESWRNLRAQGYKLTIEALPFQAARASGDIAS 1269
Query: 119 NVKYHEDFEKTKGRGFTP--VVDDPVTERVRKNTQVVSDAAYK 159
+ Y DF K +G+ P V DDP + R+ Q+ S+ Y+
Sbjct: 1270 DFLYRHDFVKERGKLIGPQSVRDDPRIQHCRRMGQLQSELQYR 1312
Score = 45.4 bits (106), Expect = 5e-05
Identities = 39/165 (23%), Positives = 73/165 (44%), Gaps = 32/165 (19%)
Query: 33 EVCKMALNMNNYKGYEKKP--------YCNAHYPKQSFTTVADT------------PENL 72
++ KM+ + KG+E+ N + K++ T +D PE++
Sbjct: 572 QIAKMSSEVEYKKGFEESKTRFHLPMDMVNIRHAKKAQTLASDLDYRKKLHEYTVLPEDM 631
Query: 73 RL---KQQSELQSQVKYKRDFEESKGRGFSIVTDTPELQRLKRTQEQISNVKYHEDFEKT 129
+ K+ LQS+++YK D KG G+ + + L++ K+ + +S Y + ++
Sbjct: 632 KTQWAKKAYGLQSELQYKADLAWMKGVGW-LTEGSLNLEQAKKAGQLVSEKNYRQRVDEL 690
Query: 130 KGRGFTPVVDDPVTERVRKNTQVVSDAAYK-----GVHPHIVEMD 169
K FT V D E +K+ ++ S AYK VH + + D
Sbjct: 691 K---FTSVTDSSQMEHAKKSQELQSGVAYKAGNEQSVHQYTISKD 732
Score = 44.3 bits (103), Expect = 1e-04
Identities = 27/100 (27%), Positives = 48/100 (48%), Gaps = 2/100 (2%)
Query: 62 FTTVADTPENLRLKQQSELQSQVKYKRDFEESKGRGFSIVTDTPELQRLKRTQEQISNVK 121
+T D P L+ + + S+ YK +E K +GF + D+ K ++ S VK
Sbjct: 727 YTISKDEPLFLQARANAANLSEKLYKSSWENQKAKGFELRLDSLTFLAAKAKRDLASEVK 786
Query: 122 YHEDFEKTKGR--GFTPVVDDPVTERVRKNTQVVSDAAYK 159
Y ED+E+++G+ G V D + +++ S+ YK
Sbjct: 787 YKEDYERSRGKLIGAKDVQGDSQMSHSLQMSKLQSELEYK 826
Score = 43.5 bits (101), Expect = 2e-04
Identities = 28/132 (21%), Positives = 57/132 (43%), Gaps = 7/132 (5%)
Query: 28 GCFHCEVCKMALNMNNYKGYEKKPYCNAHYPKQSFTTVADTPENLRLKQQSELQSQVKYK 87
G E K A + + Y + P+ +T V DTP L K +++ ++ YK
Sbjct: 1150 GTLEIEGRKKASELISESKYRQHPH------SFKYTAVTDTPNLLHAKFSNQITNERLYK 1203
Query: 88 RDFEESKGRGFSIVTDTPELQRLKRTQEQISNVKYHEDFEKTKGRGFTPVVDDPVTERVR 147
E+++ +++ PE R K +S+ +Y E + + +G+ ++ + R
Sbjct: 1204 AAGEDAR-HEYTMTLGLPEFIRAKTNAANLSDARYKESWRNLRAQGYKLTIEALPFQAAR 1262
Query: 148 KNTQVVSDAAYK 159
+ + SD Y+
Sbjct: 1263 ASGDIASDFLYR 1274
Score = 43.5 bits (101), Expect = 2e-04
Identities = 28/94 (29%), Positives = 49/94 (52%), Gaps = 7/94 (7%)
Query: 69 PENLRL---KQQSELQSQVKYKRDFEESKGRGFSIVTDTPELQRLKRTQEQISNVKYHED 125
PE+L++ K+ LQS+++YK D KG G+ + +P+++ K+ E IS KY +
Sbjct: 1357 PEDLKMAWAKKAHALQSELRYKSDLIGMKGIGW-LALRSPQMESAKKAGELISETKYRKK 1415
Query: 126 FEKTKGRGFTPVVDDPVTERVRKNTQVVSDAAYK 159
+ K FT VVD P + + ++ Y+
Sbjct: 1416 PDSIK---FTTVVDSPDLVHAKNSYMHCNERMYR 1446
Score = 42.4 bits (98), Expect = 4e-04
Identities = 37/166 (22%), Positives = 76/166 (45%), Gaps = 25/166 (15%)
Query: 76 QQSELQSQVKYKRDFEESKGRGFSIVTDTPELQRLKRTQEQISNVKYHEDFEKTKGRGFT 135
Q +++ S+V+YK+ FEESK R F + D ++ K+ Q S++ Y + + +T
Sbjct: 572 QIAKMSSEVEYKKGFEESKTR-FHLPMDMVNIRHAKKAQTLASDLDYRKKLHE-----YT 625
Query: 136 PVVDDPVTERVRKNTQVVSDAAYKGVHPHI------------VEMDRRPGIIVAPVLPGA 183
+ +D T+ +K + S+ YK + +E ++ G +V+
Sbjct: 626 VLPEDMKTQWAKKAYGLQSELQYKADLAWMKGVGWLTEGSLNLEQAKKAGQLVS------ 679
Query: 184 YQQSHSQGYGYMHQTSVSSMRSMQHSPNLRTYRAMYDYSAQDEDEV 229
++++ Q + TSV+ M+H+ + ++ Y A +E V
Sbjct: 680 -EKNYRQRVDELKFTSVTDSSQMEHAKKSQELQSGVAYKAGNEQSV 724
Score = 42.4 bits (98), Expect = 4e-04
Identities = 32/132 (24%), Positives = 59/132 (44%), Gaps = 7/132 (5%)
Query: 28 GCFHCEVCKMALNMNNYKGYEKKPYCNAHYPKQSFTTVADTPENLRLKQQSELQSQVKYK 87
G + E K A + + K Y + P FT++ DTPE ++ + S Q+ +
Sbjct: 907 GSLNVEQAKKAGELISEKKYRQHP------DALKFTSIKDTPEMVQARI-SYTQAVDRLY 959
Query: 88 RDFEESKGRGFSIVTDTPELQRLKRTQEQISNVKYHEDFEKTKGRGFTPVVDDPVTERVR 147
R+ E+ ++ D PE+ K IS +Y E + K + G+ +D + +
Sbjct: 960 REQGENIKHHYTPTADLPEVLLAKLNAMNISETRYKESWSKLRDGGYKLRLDALPFQAAK 1019
Query: 148 KNTQVVSDAAYK 159
+ +++SD YK
Sbjct: 1020 ASGEIISDYKYK 1031
Score = 42.0 bits (97), Expect = 6e-04
Identities = 31/127 (24%), Positives = 56/127 (44%), Gaps = 7/127 (5%)
Query: 33 EVCKMALNMNNYKGYEKKPYCNAHYPKQSFTTVADTPENLRLKQQSELQSQVKYKRDFEE 92
E K A + + Y KKP FTTV D+P+ + K ++ Y+ E
Sbjct: 1398 ESAKKAGELISETKYRKKP------DSIKFTTVVDSPDLVHAKNSYMHCNERMYRSGDAE 1451
Query: 93 SKGRGFSIVTDTPELQRLKRTQEQISNVKYHEDFEKTKGRGFTPVVDDPVTERVRKNTQV 152
S R ++++ D P+ R + +S+ Y +E+T+ + +D + R + ++
Sbjct: 1452 SLHR-YTLIPDHPDFTRARLNALHLSDKVYRNSWEQTRAGSYDFRLDAIPFQTARASREI 1510
Query: 153 VSDAAYK 159
SD YK
Sbjct: 1511 ASDFRYK 1517
Score = 41.2 bits (95), Expect = 0.001
Identities = 31/112 (27%), Positives = 49/112 (43%), Gaps = 4/112 (3%)
Query: 56 HYPKQSFTTVADTPENLRLKQQSELQSQVKYKRDFEESKGRGFSI---VTDTPELQRLKR 112
H K SF + TP K+ EL S +KY++DF + KG D L++ +
Sbjct: 305 HRGKGSFPAMI-TPAYQNAKKAHELASDIKYRQDFNKMKGAAHYHSLPAQDNLVLKQAQS 363
Query: 113 TQEQISNVKYHEDFEKTKGRGFTPVVDDPVTERVRKNTQVVSDAAYKGVHPH 164
+ +S KY E+++ + V D T K + S+ AYK + H
Sbjct: 364 VNKLVSENKYKENYQNHMRGRYEGVGMDRRTLHAMKVGSLASNVAYKADYKH 415
Score = 41.2 bits (95), Expect = 0.001
Identities = 29/111 (26%), Positives = 49/111 (44%), Gaps = 3/111 (2%)
Query: 60 QSFTTVADTPENLRLKQQSELQSQVKYKRDFEESKGR--GFSIVTDTPELQRLKRTQEQI 117
+ F D+ L K + +L S+VKYK D+E S+G+ G V ++ + +
Sbjct: 761 KGFELRLDSLTFLAAKAKRDLASEVKYKEDYERSRGKLIGAKDVQGDSQMSHSLQMSKLQ 820
Query: 118 SNVKYHEDFEKTKGRGFTPVVDDPVTERVRKNTQVVSDAAYKGVHPHIVEM 168
S ++Y + FE TK + +D RK + +D YK H +
Sbjct: 821 SELEYKKGFEDTKSQCHVS-LDMVHLVHARKAQHLATDVGYKTAEHHFTAL 870
Score = 40.8 bits (94), Expect = 0.001
Identities = 35/126 (27%), Positives = 56/126 (44%), Gaps = 18/126 (14%)
Query: 62 FTTVADTPENLRLKQQSELQSQVKYKRDFEESKGRGFSIVTDTPELQRLKRTQEQISNVK 121
+ +V D P LQS +YK+DF +S+ + F TD P L + KR+Q+ S+V
Sbjct: 1530 YRSVDDDPRMKHFLNVGRLQSDNEYKKDFAKSRSQ-FHSSTDQPGLLQAKRSQQLASDVH 1588
Query: 122 YHEDFEKTKGRGFTPVVDDPV--TERVRKNTQVVSDAAYKGVHPHIVEMDRRPGIIVAPV 179
Y + + P D +K Q+ SD YK +++ G+ P
Sbjct: 1589 YRQPLPQ-------PTCDPEQLGLRHAQKAHQLQSDVKYKS------DLNLTRGVGWTP- 1634
Query: 180 LPGAYQ 185
PG+Y+
Sbjct: 1635 -PGSYK 1639
Score = 37.4 bits (85), Expect = 0.014
Identities = 22/83 (26%), Positives = 40/83 (48%), Gaps = 3/83 (3%)
Query: 79 ELQSQVKYKRDFEESKGR--GFSIVTDTPELQRLKRTQEQISNVKYHEDFEKTKGRGFTP 136
E+ S +YK F +G G+ V D P ++ S+ +Y +DF K++ + F
Sbjct: 1509 EIASDFRYKEAFLRDRGLQIGYRSVDDDPRMKHFLNVGRLQSDNEYKKDFAKSRSQ-FHS 1567
Query: 137 VVDDPVTERVRKNTQVVSDAAYK 159
D P + +++ Q+ SD Y+
Sbjct: 1568 STDQPGLLQAKRSQQLASDVHYR 1590
Score = 33.9 bits (76), Expect = 0.15
Identities = 36/160 (22%), Positives = 63/160 (39%), Gaps = 21/160 (13%)
Query: 78 SELQSQVKYKRDFEESKGRGFSIVTDTPELQRLKRTQEQISNVKYHEDFEKTKGRGFTPV 137
+ LQS V YK+ FE SK + F + D L K+ Q SN Y + +T +
Sbjct: 1060 TSLQSDVNYKKGFEHSKAQ-FHLPLDMAALVHAKKAQTLASNQDYKHPLPQ-----YTSL 1113
Query: 138 VDDPVTERVRKNTQVVSDAAYKG----------VHPHIVEMDRRPGIIVAPVLPGAYQQS 187
+D +K ++ S+ Y+ V P +E++ R + ++ + +
Sbjct: 1114 AEDLRLSCAKKAHKLQSENLYRSDLNFMRGVACVIPGTLEIEGRKK--ASELISESKYRQ 1171
Query: 188 HSQGYGYMHQTSVSSMRSMQHSPNLRTYRAMYDYSAQDED 227
H + Y T ++ + S + R Y A ED
Sbjct: 1172 HPHSFKYTAVTDTPNLLHAKFSNQITNERL---YKAAGED 1208
Score = 32.7 bits (73), Expect = 0.34
Identities = 24/96 (25%), Positives = 42/96 (43%), Gaps = 6/96 (6%)
Query: 64 TVADTPENLRLKQQSELQSQVKYKRDFEESKGRGFSIVTDTPELQRLKRTQEQISNVKYH 123
+V D P ++ +LQS+++Y+R S+ + F + D L K Q S+ Y
Sbjct: 1289 SVRDDPRIQHCRRMGQLQSELQYRRGATSSQAQ-FHLPMDMVHLVHAKNAQALASDHDYR 1347
Query: 124 EDFEKTKGRGFTPVVDDPVTERVRKNTQVVSDAAYK 159
+ K FT + +D +K + S+ YK
Sbjct: 1348 TQYHK-----FTALPEDLKMAWAKKAHALQSELRYK 1378
>gi|46049105 nebulin-related anchoring protein isoform S [Homo
sapiens]
Length = 1730
Score = 125 bits (313), Expect = 5e-29
Identities = 70/198 (35%), Positives = 103/198 (52%), Gaps = 37/198 (18%)
Query: 1 MNPQ-CARCGKVVYPTEKVNCLDKYWHKGCFHCEVCKMALNMNNYKGYEKKPYCNAHYPK 59
MN Q C+RCG VYP EK++C+D+ WHK CFHCEVCKM L++NN+ ++KKPYC+AH PK
Sbjct: 1 MNVQPCSRCGYGVYPAEKISCIDQIWHKACFHCEVCKMMLSVNNFVSHQKKPYCHAHNPK 60
Query: 60 -QSFTTVADTPENLRLKQQSELQSQVKYKRDFEESK------------------------ 94
+FT+V TP NL ++ E S + + D E+ K
Sbjct: 61 NNTFTSVYHTPLNLNVRTFPEAISGIHDQEDGEQCKSVFHWDMKSKDKEGAPNRQPLANE 120
Query: 95 -------GRGFSI---VTDTPELQRLKRTQEQISNVKYHEDFEKTKGRGFTPVVDDPVTE 144
G G + PE+ R+ ++ + +Y ED+E+ +G+G P + P +
Sbjct: 121 RAYWTGYGEGNAWCPGALPDPEIVRMVEARKSLGE-EYTEDYEQPRGKGSFPAMITPAYQ 179
Query: 145 RVRKNTQVVSDAAYKGVH 162
R +K Q+ S YK H
Sbjct: 180 RAKKANQLASQVEYKRGH 197
Score = 70.1 bits (170), Expect = 2e-12
Identities = 42/125 (33%), Positives = 64/125 (51%), Gaps = 1/125 (0%)
Query: 68 TPENLRLKQQSELQSQVKYKRDFEESKGRGFSIVTDTPELQRLKRTQEQISNVKYHEDFE 127
TP R K+ ++L SQV+YKR +E R FS V DTPEL R K + S+V+Y ED+E
Sbjct: 175 TPAYQRAKKANQLASQVEYKRGHDERISR-FSTVVDTPELLRSKAGAQLQSDVRYTEDYE 233
Query: 128 KTKGRGFTPVVDDPVTERVRKNTQVVSDAAYKGVHPHIVEMDRRPGIIVAPVLPGAYQQS 187
+ +G+G P + P + ++ ++ SD Y + + P I +L
Sbjct: 234 QQRGKGSFPAMITPAYQIAKRANELASDVRYHQQYQKEMRGMAGPAIGAEGILTRECADQ 293
Query: 188 HSQGY 192
+ QGY
Sbjct: 294 YGQGY 298
Score = 65.9 bits (159), Expect = 4e-11
Identities = 49/154 (31%), Positives = 75/154 (48%), Gaps = 10/154 (6%)
Query: 62 FTTVADTPENLRLKQQSELQSQVKYKRDFEESKGRGFSIVTDTPELQRLKRTQEQISNVK 121
F+TV DTPE LR K ++LQS V+Y D+E+ +G+G TP Q KR E S+V+
Sbjct: 204 FSTVVDTPELLRSKAGAQLQSDVRYTEDYEQQRGKGSFPAMITPAYQIAKRANELASDVR 263
Query: 122 YHEDFEKTKGRGFTPVVDDPVTERVRKNTQVVSDAAYKGVHPHIVEMDRRPGIIVAPVLP 181
YH+ ++K + RG P T+ +D +G +P E R G A + P
Sbjct: 264 YHQQYQK-EMRGMA----GPAIGAEGILTRECADQYGQG-YPEEYEEHRGKGSFPAMITP 317
Query: 182 GAYQ---QSHSQGYGYMHQTSVSSMRSMQHSPNL 212
AYQ ++H ++ + M+ H +L
Sbjct: 318 -AYQNAKKAHELASDIKYRQDFNKMKGAAHYHSL 350
Score = 65.5 bits (158), Expect = 5e-11
Identities = 35/91 (38%), Positives = 54/91 (59%), Gaps = 9/91 (9%)
Query: 43 NYKG-YEKKPYCNAHYPKQSFTTVADTPENLRLKQQSELQSQVKYKRDFEESKGRGFSIV 101
NY+ YEK K ++T D P+ ++ K ++L S+VKYK +E++KG+GF +
Sbjct: 511 NYRADYEKN--------KLNYTLPQDVPQLVKAKTNAKLFSEVKYKEGWEKTKGKGFEMK 562
Query: 102 TDTPELQRLKRTQEQISNVKYHEDFEKTKGR 132
D L K + E SN+KY E++EKTKG+
Sbjct: 563 LDAMSLLAAKASGELASNIKYKEEYEKTKGK 593
Score = 62.4 bits (150), Expect = 4e-10
Identities = 32/101 (31%), Positives = 58/101 (57%), Gaps = 1/101 (0%)
Query: 59 KQSFTTVADTPENLRLKQQSELQSQVKYKRDFEESKGRGFSIVTDTPELQRLKRTQEQIS 118
K +++V DTP+ ++ K ++ S V Y+ D+E++K +++ D P+L + K + S
Sbjct: 485 KLKYSSVTDTPQIVQAKINAQQLSHVNYRADYEKNK-LNYTLPQDVPQLVKAKTNAKLFS 543
Query: 119 NVKYHEDFEKTKGRGFTPVVDDPVTERVRKNTQVVSDAAYK 159
VKY E +EKTKG+GF +D + + ++ S+ YK
Sbjct: 544 EVKYKEGWEKTKGKGFEMKLDAMSLLAAKASGELASNIKYK 584
Score = 50.8 bits (120), Expect = 1e-06
Identities = 35/108 (32%), Positives = 49/108 (45%), Gaps = 2/108 (1%)
Query: 59 KQSFTTVADTPENLRLKQQSELQSQVKYKRDFEESKGRGFSIVTDTPELQRLKRTQEQIS 118
K +T AD PE L K + S+ +YK + + + G+ + D Q K + E IS
Sbjct: 1002 KHHYTPTADLPEVLLAKLNAMNISETRYKESWSKLRDGGYKLRLDALPFQAAKASGEIIS 1061
Query: 119 NVKYHEDFEKTKGR--GFTPVVDDPVTERVRKNTQVVSDAAYKGVHPH 164
+ KY E FEK KG+ G + DD T + SD YK H
Sbjct: 1062 DYKYKEAFEKMKGQMLGSRSLEDDISLAHSVYATSLQSDVNYKKGFEH 1109
Score = 47.0 bits (110), Expect = 2e-05
Identities = 41/163 (25%), Positives = 68/163 (41%), Gaps = 12/163 (7%)
Query: 27 KGCFHCEVCKMALNMNNYKGYEKKPYCNAHYPKQSFTTVADTPENLRLKQQSELQSQVKY 86
+G + E K A + + K Y ++ + FT+V D+ + K+ ELQS V Y
Sbjct: 698 EGSLNLEQAKKAGQLVSEKNYRQR------VDELKFTSVTDSSQMEHAKKSQELQSGVAY 751
Query: 87 KRDFEESKGRGFSIVTDTPELQRLKRTQEQISNVKYHEDFEKTKGRGFTPVVDDPVTERV 146
K E+S + ++I D P + + +S Y +E K +GF +D
Sbjct: 752 KAGNEQSVHQ-YTISKDEPLFLQARANAANLSEKLYKSSWENQKAKGFELRLDSLTFLAA 810
Query: 147 RKNTQVVSDAAYKGVHPHIVEMDRRPGIIVAPVLPGAYQQSHS 189
+ + S+ YK + R +I A + G Q SHS
Sbjct: 811 KAKRDLASEVKYKEDYER-----SRGKLIGAKDVQGDSQMSHS 848
Score = 45.8 bits (107), Expect = 4e-05
Identities = 25/103 (24%), Positives = 47/103 (45%), Gaps = 2/103 (1%)
Query: 59 KQSFTTVADTPENLRLKQQSELQSQVKYKRDFEESKGRGFSIVTDTPELQRLKRTQEQIS 118
+ +T PE +R K + S +YK + + +G+ + + Q + + + S
Sbjct: 1245 RHEYTMTLGLPEFIRAKTNAANLSDARYKESWRNLRAQGYKLTIEALPFQAARASGDIAS 1304
Query: 119 NVKYHEDFEKTKGRGFTP--VVDDPVTERVRKNTQVVSDAAYK 159
+ Y DF K +G+ P V DDP + R+ Q+ S+ Y+
Sbjct: 1305 DFLYRHDFVKERGKLIGPQSVRDDPRIQHCRRMGQLQSELQYR 1347
Score = 45.4 bits (106), Expect = 5e-05
Identities = 29/98 (29%), Positives = 51/98 (52%), Gaps = 4/98 (4%)
Query: 70 ENLRLKQQ---SELQSQVKYKRDFEESKGRGFSIVTDTPELQRLKRTQEQISNVKYHEDF 126
+NL LKQ ++L S+V+YK+D E S+G + +TP+ + + + + S+ KY E++
Sbjct: 354 DNLVLKQAQSVNKLVSEVEYKKDLESSRGHSINYC-ETPQFRNVSKISKFTSDNKYKENY 412
Query: 127 EKTKGRGFTPVVDDPVTERVRKNTQVVSDAAYKGVHPH 164
+ + V D T K + S+ AYK + H
Sbjct: 413 QNHMRGRYEGVGMDRRTLHAMKVGSLASNVAYKADYKH 450
Score = 45.4 bits (106), Expect = 5e-05
Identities = 39/165 (23%), Positives = 73/165 (44%), Gaps = 32/165 (19%)
Query: 33 EVCKMALNMNNYKGYEKKP--------YCNAHYPKQSFTTVADT------------PENL 72
++ KM+ + KG+E+ N + K++ T +D PE++
Sbjct: 607 QIAKMSSEVEYKKGFEESKTRFHLPMDMVNIRHAKKAQTLASDLDYRKKLHEYTVLPEDM 666
Query: 73 RL---KQQSELQSQVKYKRDFEESKGRGFSIVTDTPELQRLKRTQEQISNVKYHEDFEKT 129
+ K+ LQS+++YK D KG G+ + + L++ K+ + +S Y + ++
Sbjct: 667 KTQWAKKAYGLQSELQYKADLAWMKGVGW-LTEGSLNLEQAKKAGQLVSEKNYRQRVDEL 725
Query: 130 KGRGFTPVVDDPVTERVRKNTQVVSDAAYK-----GVHPHIVEMD 169
K FT V D E +K+ ++ S AYK VH + + D
Sbjct: 726 K---FTSVTDSSQMEHAKKSQELQSGVAYKAGNEQSVHQYTISKD 767
Score = 44.3 bits (103), Expect = 1e-04
Identities = 27/100 (27%), Positives = 48/100 (48%), Gaps = 2/100 (2%)
Query: 62 FTTVADTPENLRLKQQSELQSQVKYKRDFEESKGRGFSIVTDTPELQRLKRTQEQISNVK 121
+T D P L+ + + S+ YK +E K +GF + D+ K ++ S VK
Sbjct: 762 YTISKDEPLFLQARANAANLSEKLYKSSWENQKAKGFELRLDSLTFLAAKAKRDLASEVK 821
Query: 122 YHEDFEKTKGR--GFTPVVDDPVTERVRKNTQVVSDAAYK 159
Y ED+E+++G+ G V D + +++ S+ YK
Sbjct: 822 YKEDYERSRGKLIGAKDVQGDSQMSHSLQMSKLQSELEYK 861
Score = 43.5 bits (101), Expect = 2e-04
Identities = 28/132 (21%), Positives = 57/132 (43%), Gaps = 7/132 (5%)
Query: 28 GCFHCEVCKMALNMNNYKGYEKKPYCNAHYPKQSFTTVADTPENLRLKQQSELQSQVKYK 87
G E K A + + Y + P+ +T V DTP L K +++ ++ YK
Sbjct: 1185 GTLEIEGRKKASELISESKYRQHPH------SFKYTAVTDTPNLLHAKFSNQITNERLYK 1238
Query: 88 RDFEESKGRGFSIVTDTPELQRLKRTQEQISNVKYHEDFEKTKGRGFTPVVDDPVTERVR 147
E+++ +++ PE R K +S+ +Y E + + +G+ ++ + R
Sbjct: 1239 AAGEDAR-HEYTMTLGLPEFIRAKTNAANLSDARYKESWRNLRAQGYKLTIEALPFQAAR 1297
Query: 148 KNTQVVSDAAYK 159
+ + SD Y+
Sbjct: 1298 ASGDIASDFLYR 1309
Score = 43.5 bits (101), Expect = 2e-04
Identities = 28/94 (29%), Positives = 49/94 (52%), Gaps = 7/94 (7%)
Query: 69 PENLRL---KQQSELQSQVKYKRDFEESKGRGFSIVTDTPELQRLKRTQEQISNVKYHED 125
PE+L++ K+ LQS+++YK D KG G+ + +P+++ K+ E IS KY +
Sbjct: 1392 PEDLKMAWAKKAHALQSELRYKSDLIGMKGIGW-LALRSPQMESAKKAGELISETKYRKK 1450
Query: 126 FEKTKGRGFTPVVDDPVTERVRKNTQVVSDAAYK 159
+ K FT VVD P + + ++ Y+
Sbjct: 1451 PDSIK---FTTVVDSPDLVHAKNSYMHCNERMYR 1481
Score = 42.4 bits (98), Expect = 4e-04
Identities = 37/166 (22%), Positives = 76/166 (45%), Gaps = 25/166 (15%)
Query: 76 QQSELQSQVKYKRDFEESKGRGFSIVTDTPELQRLKRTQEQISNVKYHEDFEKTKGRGFT 135
Q +++ S+V+YK+ FEESK R F + D ++ K+ Q S++ Y + + +T
Sbjct: 607 QIAKMSSEVEYKKGFEESKTR-FHLPMDMVNIRHAKKAQTLASDLDYRKKLHE-----YT 660
Query: 136 PVVDDPVTERVRKNTQVVSDAAYKGVHPHI------------VEMDRRPGIIVAPVLPGA 183
+ +D T+ +K + S+ YK + +E ++ G +V+
Sbjct: 661 VLPEDMKTQWAKKAYGLQSELQYKADLAWMKGVGWLTEGSLNLEQAKKAGQLVS------ 714
Query: 184 YQQSHSQGYGYMHQTSVSSMRSMQHSPNLRTYRAMYDYSAQDEDEV 229
++++ Q + TSV+ M+H+ + ++ Y A +E V
Sbjct: 715 -EKNYRQRVDELKFTSVTDSSQMEHAKKSQELQSGVAYKAGNEQSV 759
Score = 42.4 bits (98), Expect = 4e-04
Identities = 32/132 (24%), Positives = 59/132 (44%), Gaps = 7/132 (5%)
Query: 28 GCFHCEVCKMALNMNNYKGYEKKPYCNAHYPKQSFTTVADTPENLRLKQQSELQSQVKYK 87
G + E K A + + K Y + P FT++ DTPE ++ + S Q+ +
Sbjct: 942 GSLNVEQAKKAGELISEKKYRQHP------DALKFTSIKDTPEMVQARI-SYTQAVDRLY 994
Query: 88 RDFEESKGRGFSIVTDTPELQRLKRTQEQISNVKYHEDFEKTKGRGFTPVVDDPVTERVR 147
R+ E+ ++ D PE+ K IS +Y E + K + G+ +D + +
Sbjct: 995 REQGENIKHHYTPTADLPEVLLAKLNAMNISETRYKESWSKLRDGGYKLRLDALPFQAAK 1054
Query: 148 KNTQVVSDAAYK 159
+ +++SD YK
Sbjct: 1055 ASGEIISDYKYK 1066
Score = 42.0 bits (97), Expect = 6e-04
Identities = 31/127 (24%), Positives = 56/127 (44%), Gaps = 7/127 (5%)
Query: 33 EVCKMALNMNNYKGYEKKPYCNAHYPKQSFTTVADTPENLRLKQQSELQSQVKYKRDFEE 92
E K A + + Y KKP FTTV D+P+ + K ++ Y+ E
Sbjct: 1433 ESAKKAGELISETKYRKKP------DSIKFTTVVDSPDLVHAKNSYMHCNERMYRSGDAE 1486
Query: 93 SKGRGFSIVTDTPELQRLKRTQEQISNVKYHEDFEKTKGRGFTPVVDDPVTERVRKNTQV 152
S R ++++ D P+ R + +S+ Y +E+T+ + +D + R + ++
Sbjct: 1487 SLHR-YTLIPDHPDFTRARLNALHLSDKVYRNSWEQTRAGSYDFRLDAIPFQTARASREI 1545
Query: 153 VSDAAYK 159
SD YK
Sbjct: 1546 ASDFRYK 1552
Score = 41.2 bits (95), Expect = 0.001
Identities = 29/111 (26%), Positives = 49/111 (44%), Gaps = 3/111 (2%)
Query: 60 QSFTTVADTPENLRLKQQSELQSQVKYKRDFEESKGR--GFSIVTDTPELQRLKRTQEQI 117
+ F D+ L K + +L S+VKYK D+E S+G+ G V ++ + +
Sbjct: 796 KGFELRLDSLTFLAAKAKRDLASEVKYKEDYERSRGKLIGAKDVQGDSQMSHSLQMSKLQ 855
Query: 118 SNVKYHEDFEKTKGRGFTPVVDDPVTERVRKNTQVVSDAAYKGVHPHIVEM 168
S ++Y + FE TK + +D RK + +D YK H +
Sbjct: 856 SELEYKKGFEDTKSQCHVS-LDMVHLVHARKAQHLATDVGYKTAEHHFTAL 905
Score = 40.8 bits (94), Expect = 0.001
Identities = 35/126 (27%), Positives = 56/126 (44%), Gaps = 18/126 (14%)
Query: 62 FTTVADTPENLRLKQQSELQSQVKYKRDFEESKGRGFSIVTDTPELQRLKRTQEQISNVK 121
+ +V D P LQS +YK+DF +S+ + F TD P L + KR+Q+ S+V
Sbjct: 1565 YRSVDDDPRMKHFLNVGRLQSDNEYKKDFAKSRSQ-FHSSTDQPGLLQAKRSQQLASDVH 1623
Query: 122 YHEDFEKTKGRGFTPVVDDPV--TERVRKNTQVVSDAAYKGVHPHIVEMDRRPGIIVAPV 179
Y + + P D +K Q+ SD YK +++ G+ P
Sbjct: 1624 YRQPLPQ-------PTCDPEQLGLRHAQKAHQLQSDVKYKS------DLNLTRGVGWTP- 1669
Query: 180 LPGAYQ 185
PG+Y+
Sbjct: 1670 -PGSYK 1674
Score = 37.4 bits (85), Expect = 0.014
Identities = 22/83 (26%), Positives = 40/83 (48%), Gaps = 3/83 (3%)
Query: 79 ELQSQVKYKRDFEESKGR--GFSIVTDTPELQRLKRTQEQISNVKYHEDFEKTKGRGFTP 136
E+ S +YK F +G G+ V D P ++ S+ +Y +DF K++ + F
Sbjct: 1544 EIASDFRYKEAFLRDRGLQIGYRSVDDDPRMKHFLNVGRLQSDNEYKKDFAKSRSQ-FHS 1602
Query: 137 VVDDPVTERVRKNTQVVSDAAYK 159
D P + +++ Q+ SD Y+
Sbjct: 1603 STDQPGLLQAKRSQQLASDVHYR 1625
Score = 33.9 bits (76), Expect = 0.15
Identities = 36/160 (22%), Positives = 63/160 (39%), Gaps = 21/160 (13%)
Query: 78 SELQSQVKYKRDFEESKGRGFSIVTDTPELQRLKRTQEQISNVKYHEDFEKTKGRGFTPV 137
+ LQS V YK+ FE SK + F + D L K+ Q SN Y + +T +
Sbjct: 1095 TSLQSDVNYKKGFEHSKAQ-FHLPLDMAALVHAKKAQTLASNQDYKHPLPQ-----YTSL 1148
Query: 138 VDDPVTERVRKNTQVVSDAAYKG----------VHPHIVEMDRRPGIIVAPVLPGAYQQS 187
+D +K ++ S+ Y+ V P +E++ R + ++ + +
Sbjct: 1149 AEDLRLSCAKKAHKLQSENLYRSDLNFMRGVACVIPGTLEIEGRKK--ASELISESKYRQ 1206
Query: 188 HSQGYGYMHQTSVSSMRSMQHSPNLRTYRAMYDYSAQDED 227
H + Y T ++ + S + R Y A ED
Sbjct: 1207 HPHSFKYTAVTDTPNLLHAKFSNQITNERL---YKAAGED 1243
Score = 32.7 bits (73), Expect = 0.34
Identities = 24/96 (25%), Positives = 42/96 (43%), Gaps = 6/96 (6%)
Query: 64 TVADTPENLRLKQQSELQSQVKYKRDFEESKGRGFSIVTDTPELQRLKRTQEQISNVKYH 123
+V D P ++ +LQS+++Y+R S+ + F + D L K Q S+ Y
Sbjct: 1324 SVRDDPRIQHCRRMGQLQSELQYRRGATSSQAQ-FHLPMDMVHLVHAKNAQALASDHDYR 1382
Query: 124 EDFEKTKGRGFTPVVDDPVTERVRKNTQVVSDAAYK 159
+ K FT + +D +K + S+ YK
Sbjct: 1383 TQYHK-----FTALPEDLKMAWAKKAHALQSELRYK 1413
>gi|115527120 nebulin [Homo sapiens]
Length = 6669
Score = 102 bits (254), Expect = 4e-22
Identities = 49/73 (67%), Positives = 59/73 (80%), Gaps = 1/73 (1%)
Query: 197 QTSVSSMRSMQHSPNLRTYRAMYDYSAQDEDEVSFRDGDYIVNVQPIDDGWMYGTVQRTG 256
QT+VSS+ S + + +RAMYDY A D DEVSF+DGD I+NVQ ID+GWMYGTVQRTG
Sbjct: 6598 QTTVSSIPSHPSTAG-KIFRAMYDYMAADADEVSFKDGDAIINVQAIDEGWMYGTVQRTG 6656
Query: 257 RTGMLPANYIEFV 269
RTGMLPANY+E +
Sbjct: 6657 RTGMLPANYVEAI 6669
Score = 99.0 bits (245), Expect = 4e-21
Identities = 52/104 (50%), Positives = 67/104 (64%), Gaps = 1/104 (0%)
Query: 68 TPENLRLKQQSELQSQVKYKRDFEESKGRGFSIVTDTPELQRLKRTQEQISNVKYHEDFE 127
TPE R K+ E S V Y F + + V DTPE++R++ TQ IS VKYHEDFE
Sbjct: 6384 TPEMERAKRNQENISSVLYSDSFRKQIQGKAAYVLDTPEMRRVRETQRHISTVKYHEDFE 6443
Query: 128 KTKGRGFTPVVDDPVTERVRKNTQVVSDAAYKGVHPHIVEMDRR 171
K KG FTPVV DP+TERV+KN Q SD Y+G+ +VEM+++
Sbjct: 6444 KHKG-CFTPVVTDPITERVKKNMQDFSDINYRGIQRKVVEMEQK 6486
Score = 78.2 bits (191), Expect = 7e-15
Identities = 42/115 (36%), Positives = 65/115 (56%), Gaps = 1/115 (0%)
Query: 48 EKKPYCNAHYPKQSFTTVADTPENLRLKQQSELQSQVKYKRDFEESKGRGFSIVTDTPEL 107
EKK + K + V D P +L K + SQ+KY++++E+SK + F+ + DTPE
Sbjct: 5403 EKKYRADYEQRKDKYHLVVDEPRHLLAKTAGDQISQIKYRKNYEKSKDK-FTSIVDTPEH 5461
Query: 108 QRLKRTQEQISNVKYHEDFEKTKGRGFTPVVDDPVTERVRKNTQVVSDAAYKGVH 162
R + +QIS++ Y ++ K K RG+T + D P+ VRK VSD YK V+
Sbjct: 5462 LRTTKVNKQISDILYKLEYNKAKPRGYTTIHDTPMLLHVRKVKDEVSDLKYKEVY 5516
Score = 73.9 bits (180), Expect = 1e-13
Identities = 42/106 (39%), Positives = 61/106 (57%), Gaps = 2/106 (1%)
Query: 54 NAHYPKQSFTTVADTPENLRLKQQSELQSQVKYKRDFEESKGRGFSIVTDTPELQRLKRT 113
+A K +FT+V DTPE + +Q L SQ KYK D E+S + V DTPE+QR++
Sbjct: 6052 SAEMEKANFTSVVDTPEIIHAQQVKNLSSQKKYKEDAEKSMSY-YETVLDTPEIQRVREN 6110
Query: 114 QEQISNVKYHEDFEKTKGRGFTPVVDDPVTERVRKNTQVVSDAAYK 159
Q+ S ++Y D + +KG+ T V D P RV++N + S YK
Sbjct: 6111 QKNFSLLQYQCDLKNSKGK-ITVVQDTPEILRVKENQKNFSSVLYK 6155
Score = 73.6 bits (179), Expect = 2e-13
Identities = 47/141 (33%), Positives = 70/141 (49%), Gaps = 5/141 (3%)
Query: 22 DKYWHKG--CFHCEVCKMALNMNNYKGYEKKPYCNA-HYPKQSFTTVADTPENLRLKQQS 78
D W KG C+ + L N Y K Y K F VAD+P N K +
Sbjct: 5339 DLTWLKGIGCYAYDTPDFTLAEKNKTLYSKYKYKEVFERTKSDFKYVADSPINRHFKYAT 5398
Query: 79 ELQSQVKYKRDFEESKGRGFSIVTDTPELQRLKRTQEQISNVKYHEDFEKTKGRGFTPVV 138
+L ++ KY+ D+E+ K + + +V D P K +QIS +KY +++EK+K + FT +V
Sbjct: 5399 QLMNEKKYRADYEQRKDK-YHLVVDEPRHLLAKTAGDQISQIKYRKNYEKSKDK-FTSIV 5456
Query: 139 DDPVTERVRKNTQVVSDAAYK 159
D P R K + +SD YK
Sbjct: 5457 DTPEHLRTTKVNKQISDILYK 5477
Score = 67.0 bits (162), Expect = 2e-11
Identities = 44/118 (37%), Positives = 61/118 (51%), Gaps = 11/118 (9%)
Query: 43 NYKGYEKKPY-CNAHYPKQSFTTVADTPENLRLKQQSELQSQVKYKRDFEESKGRGFSIV 101
N K + Y C+ K T V DTPE LR+K+ + S V YK D G
Sbjct: 6110 NQKNFSLLQYQCDLKNSKGKITVVQDTPEILRVKENQKNFSSVLYKEDVSPGTAIG---- 6165
Query: 102 TDTPELQRLKRTQEQISNVKYHEDFEKTKGRGFTPVVDDPVTERVRKNTQVVSDAAYK 159
TPE+ R+K+TQ+ IS+VKY E G+G TP+ D P +RV++ + +S YK
Sbjct: 6166 -KTPEMMRVKQTQDHISSVKYKEAI----GQG-TPIPDLPEVKRVKETQKHISSVMYK 6217
Score = 63.2 bits (152), Expect = 2e-10
Identities = 28/86 (32%), Positives = 54/86 (62%), Gaps = 8/86 (9%)
Query: 45 KGYEKKPYCNAHYPKQSFTTVADTPENLRLKQQSELQSQVKYKRDFEESKGRGFSIVTDT 104
K YEK K FT++ DTPE+LR + ++ S + YK ++ ++K RG++ + DT
Sbjct: 5443 KNYEKS--------KDKFTSIVDTPEHLRTTKVNKQISDILYKLEYNKAKPRGYTTIHDT 5494
Query: 105 PELQRLKRTQEQISNVKYHEDFEKTK 130
P L +++ ++++S++KY E +++ K
Sbjct: 5495 PMLLHVRKVKDEVSDLKYKEVYQRNK 5520
Score = 60.5 bits (145), Expect = 2e-09
Identities = 39/125 (31%), Positives = 65/125 (52%), Gaps = 10/125 (8%)
Query: 36 KMALNMNNYKGYEKKPYCNAHYPKQSFTTVADTPENLRLKQQSELQSQVKYKRDFEESKG 95
++A + K YEK K + T+ D E L LK+ +ELQS VKYK +E+ +G
Sbjct: 5860 QLASSYQYKKKYEKS--------KGHYHTIPDNLEQLHLKEATELQSIVKYKEKYEKERG 5911
Query: 96 RGFSIVTDTPELQRLKRTQEQISNVKYHEDFEKT-KGRGFTPVVDDPVTERVRKNTQVVS 154
+ + +TP K +Q+ S +Y +D+E++ KGR T + P V+ T++ S
Sbjct: 5912 KPM-LDFETPTYITAKESQQMQSGKEYRKDYEESIKGRNLTGLEVTPALLHVKYATKIAS 5970
Query: 155 DAAYK 159
+ Y+
Sbjct: 5971 EKEYR 5975
Score = 60.1 bits (144), Expect = 2e-09
Identities = 38/120 (31%), Positives = 64/120 (53%), Gaps = 10/120 (8%)
Query: 40 NMNNYKGYEKKPYCNAHYPKQSFTTVADTPENLRLKQQSELQSQVKYKRDFEESKGRGFS 99
N+++ K Y++ + Y + TV DTPE R+++ + S ++Y+ D + SKG+ +
Sbjct: 6077 NLSSQKKYKEDAEKSMSY----YETVLDTPEIQRVRENQKNFSLLQYQCDLKNSKGK-IT 6131
Query: 100 IVTDTPELQRLKRTQEQISNVKYHEDFEKTKGRGFTPVVDDPVTERVRKNTQVVSDAAYK 159
+V DTPE+ R+K Q+ S+V Y ED G TP + RV++ +S YK
Sbjct: 6132 VVQDTPEILRVKENQKNFSSVLYKEDVSPGTAIGKTPEM-----MRVKQTQDHISSVKYK 6186
Score = 59.3 bits (142), Expect = 3e-09
Identities = 36/94 (38%), Positives = 53/94 (56%), Gaps = 5/94 (5%)
Query: 68 TPENLRLKQQSELQSQVKYKRDFEESKGRGFSIVTDTPELQRLKRTQEQISNVKYHEDFE 127
TP ++ +L S KYK FE++KG+ ++ TDTPEL+R+K+ Q+Q+S VKY D +
Sbjct: 83 TPYIAHSQKMQDLFSPNKYKEKFEKTKGQPYASTTDTPELRRIKKVQDQLSEVKYRMDGD 142
Query: 128 KTKGRGFTPVVDDPV--TERVRKNTQVVSDAAYK 159
K VD+ E +K +Q VS YK
Sbjct: 143 VAK---TICHVDEKAKDIEHAKKVSQQVSKVLYK 173
Score = 58.9 bits (141), Expect = 4e-09
Identities = 31/95 (32%), Positives = 56/95 (58%), Gaps = 2/95 (2%)
Query: 67 DTPENLRLKQQSELQSQVKYKRDFEES-KGRGFSIVTDTPELQRLKRTQEQISNVKYHED 125
+TP + K+ ++QS +Y++D+EES KGR + + TP L +K + S +Y +D
Sbjct: 5918 ETPTYITAKESQQMQSGKEYRKDYEESIKGRNLTGLEVTPALLHVKYATKIASEKEYRKD 5977
Query: 126 FEKT-KGRGFTPVVDDPVTERVRKNTQVVSDAAYK 159
E++ +G+G T + D P R + TQ++++ YK
Sbjct: 5978 LEESIRGKGLTEMEDTPDMLRAKNATQILNEKEYK 6012
Score = 58.2 bits (139), Expect = 8e-09
Identities = 34/102 (33%), Positives = 54/102 (52%), Gaps = 3/102 (2%)
Query: 60 QSFTTVADTPENLRLKQQSELQSQVKYKRDFE-ESKGRGF-SIVTDTPELQRLKRTQEQI 117
+ T + DTP+ LR K +++ ++ +YKRD E E KGRG ++ +TP+ R + +
Sbjct: 5985 KGLTEMEDTPDMLRAKNATQILNEKEYKRDLELEVKGRGLNAMANETPDFMRARNATDIA 6044
Query: 118 SNVKYHEDFEKTKGRGFTPVVDDPVTERVRKNTQVVSDAAYK 159
S +KY + E K FT VVD P ++ + S YK
Sbjct: 6045 SQIKYKQSAEMEKA-NFTSVVDTPEIIHAQQVKNLSSQKKYK 6085
Score = 57.8 bits (138), Expect = 1e-08
Identities = 42/160 (26%), Positives = 73/160 (45%), Gaps = 7/160 (4%)
Query: 59 KQSFTTVADTPENLRLKQQSELQSQVKYKRDFEESKGRGFSIVTDTPELQRLKRTQEQIS 118
K +T D P+ L+ K + S V YKRD+ + +G +++ D + K ++ S
Sbjct: 1269 KHKYTMSPDLPQFLQAKCNAYNISDVCYKRDWHDLIAKGNNVLGDAIPITAAKASRNIAS 1328
Query: 119 NVKYHEDFEKTKGR--GFTPVVDDPVTERVRKNTQVVSDAAYKGVHPHIVEMDRRPGIIV 176
+ KY E +EK+KG+ GF + DDP ++ SD YK + + PG +V
Sbjct: 1329 DYKYKEAYEKSKGKHVGFRSLQDDPKLVHYMNVAKLQSDREYKKNYENTKTSYHTPGDMV 1388
Query: 177 APVLPGAYQQSHSQGYGYM----HQTSVSSMRSMQHSPNL 212
+ + Q + Y H T + S++H+ N+
Sbjct: 1389 S-ITAAKMAQDVATNVNYKQPLHHYTYLPDAMSLEHTRNV 1427
Score = 57.4 bits (137), Expect = 1e-08
Identities = 38/141 (26%), Positives = 72/141 (51%), Gaps = 12/141 (8%)
Query: 42 NNYKGYEKKPYCNAHYPKQSFTTVADTPENLRLKQQSELQSQVKYKRDFEESKGR-GFSI 100
N YK + KK H + S+TT+ +T + + +K+ ++ S YK+ F + KG+ +SI
Sbjct: 5650 NKYKDHVKK-----HLAQGSYTTLPETRDTVHVKEVTKHVSDTNYKKKFVKEKGKSNYSI 5704
Query: 101 VTDTPELQRLKRTQEQISNVKYHEDFEKTKGRGFTPVVDDPVTERVRKNTQVVSDAAYKG 160
+ + PE++ ++ S+V Y +D + + +T V D P ++ + + S+ Y+
Sbjct: 5705 MLEPPEVKHAMEVAKKQSDVAYRKDAK--ENLHYTTVADRPDIKKATQAAKQASEVEYRA 5762
Query: 161 VH----PHIVEMDRRPGIIVA 177
H H + M RP I +A
Sbjct: 5763 KHRKEGSHGLSMLGRPDIEMA 5783
Score = 57.4 bits (137), Expect = 1e-08
Identities = 32/103 (31%), Positives = 58/103 (56%), Gaps = 3/103 (2%)
Query: 60 QSFTTVADTPENLRLKQQSELQSQVKYKRDFEES-KGRGFSIVTDTPELQRLKRTQEQIS 118
++ T + TP L +K +++ S+ +Y++D EES +G+G + + DTP++ R K + ++
Sbjct: 5948 RNLTGLEVTPALLHVKYATKIASEKEYRKDLEESIRGKGLTEMEDTPDMLRAKNATQILN 6007
Query: 119 NVKYHEDFE-KTKGRGFTPVVDD-PVTERVRKNTQVVSDAAYK 159
+Y D E + KGRG + ++ P R R T + S YK
Sbjct: 6008 EKEYKRDLELEVKGRGLNAMANETPDFMRARNATDIASQIKYK 6050
Score = 56.2 bits (134), Expect = 3e-08
Identities = 39/97 (40%), Positives = 52/97 (53%), Gaps = 10/97 (10%)
Query: 63 TTVADTPENLRLKQQSELQSQVKYKRDFEESKGRGFSIVTDTPELQRLKRTQEQISNVKY 122
T +A TPE R+K E S V YK E+ G+ + TPE+QR+KR QE IS+V Y
Sbjct: 6286 TPLAVTPEMERVKHNQENISSVLYK----ENVGKATATPV-TPEMQRVKRNQENISSVLY 6340
Query: 123 HEDFEKTKGRGFTPVVDDPVTERVRKNTQVVSDAAYK 159
E+ K FTP + ERV++N + S YK
Sbjct: 6341 KENLGKATPTPFTPEM-----ERVKRNQENFSSVLYK 6372
Score = 54.7 bits (130), Expect = 8e-08
Identities = 35/136 (25%), Positives = 65/136 (47%), Gaps = 3/136 (2%)
Query: 27 KGCFHCEVCKMALNMNNYKGYEKKPYCNA-HYPKQSFTTVADTPENLRLKQQSELQSQVK 85
K + + + ALN +N +K+ Y + K + + DTP+ L + S
Sbjct: 1724 KFTYAMDTMEQALNKSNKLNMDKRLYTEKWNKDKTTIHVMPDTPDILLSRVNQITMSDKL 1783
Query: 86 YKRDFEESKGRGFSIVTDTPELQRLKRTQEQISNVKYHEDFEKTKGR--GFTPVVDDPVT 143
YK +EE K +G+ + D ++ + +++ S+ KY + +E+ KG+ GF + DDP
Sbjct: 1784 YKAGWEEEKKKGYDLRPDAIAIKAARASRDIASDYKYKKAYEQAKGKHIGFRSLEDDPKL 1843
Query: 144 ERVRKNTQVVSDAAYK 159
+ ++ SD YK
Sbjct: 1844 VHFMQVAKMQSDREYK 1859
Score = 54.7 bits (130), Expect = 8e-08
Identities = 40/97 (41%), Positives = 54/97 (55%), Gaps = 12/97 (12%)
Query: 63 TTVADTPENLRLKQQSELQSQVKYKRDFEESKGRGFSIVTDTPELQRLKRTQEQISNVKY 122
TTV TPE R+K+ E S V YK E+ G+G TPE++R+KR QE S+V Y
Sbjct: 6226 TTV--TPEIERVKRNQENFSSVLYK----ENLGKGIPTPI-TPEMERVKRNQENFSSVLY 6278
Query: 123 HEDFEKTKGRGFTPVVDDPVTERVRKNTQVVSDAAYK 159
E+ G+G TP+ P ERV+ N + +S YK
Sbjct: 6279 KENM----GKG-TPLAVTPEMERVKHNQENISSVLYK 6310
Score = 54.3 bits (129), Expect = 1e-07
Identities = 38/119 (31%), Positives = 53/119 (44%), Gaps = 9/119 (7%)
Query: 43 NYKGYEKKPYCNAHYPKQSFTTVADTPENLRLKQQSELQSQVKYKRDFEESKGRGFSIVT 102
NYK + H P DTP ++ K + S YK+D+E+SK + F I
Sbjct: 525 NYKAKHESEKFKCHIPP-------DTPAFIQHKVNAYNLSDNLYKQDWEKSKAKKFDIKV 577
Query: 103 DTPELQRLKRTQEQISNVKYHEDFEKTKGR--GFTPVVDDPVTERVRKNTQVVSDAAYK 159
D L K + S+V Y +D+EK KG+ G + DDP K + SD YK
Sbjct: 578 DAIPLLAAKANTKNTSDVMYKKDYEKNKGKMIGVLSINDDPKMLHSLKVAKNQSDRLYK 636
Score = 53.9 bits (128), Expect = 1e-07
Identities = 38/98 (38%), Positives = 53/98 (54%), Gaps = 12/98 (12%)
Query: 63 TTVADTPENLRLKQQSELQSQVKYKRDFEESKGRGFSIVTDTPELQRLKRTQEQISNVKY 122
T + D PE R+K+ + S V YK E+ G G T TPE++R+KR QE S+V Y
Sbjct: 6193 TPIPDLPEVKRVKETQKHISSVMYK----ENLGTGIP-TTVTPEIERVKRNQENFSSVLY 6247
Query: 123 HEDFEKTKGRGF-TPVVDDPVTERVRKNTQVVSDAAYK 159
E+ G+G TP+ P ERV++N + S YK
Sbjct: 6248 KENL----GKGIPTPIT--PEMERVKRNQENFSSVLYK 6279
Score = 53.5 bits (127), Expect = 2e-07
Identities = 36/119 (30%), Positives = 55/119 (46%), Gaps = 9/119 (7%)
Query: 43 NYKGYEKKPYCNAHYPKQSFTTVADTPENLRLKQQSELQSQVKYKRDFEESKGRGFSIVT 102
NYK + H P AD P+ ++ + + S YK+D+E+SK + F I
Sbjct: 772 NYKAKHEGEKFKCHIP-------ADAPQFIQHRVNAYNLSDNVYKQDWEKSKAKKFDIKV 824
Query: 103 DTPELQRLKRTQEQISNVKYHEDFEKTKGR--GFTPVVDDPVTERVRKNTQVVSDAAYK 159
D L K + S+V Y +D+EK+KG+ G + DDP K + SD Y+
Sbjct: 825 DAIPLLAAKANTKNTSDVMYKKDYEKSKGKMIGALSINDDPKMLHSLKTAKNQSDREYR 883
Score = 53.1 bits (126), Expect = 2e-07
Identities = 28/95 (29%), Positives = 50/95 (52%), Gaps = 2/95 (2%)
Query: 67 DTPENLRLKQQSELQSQVKYKRDFEESKGRGFSIVTDTPELQRLKRTQEQISNVKYHEDF 126
D P+ ++ K + S+ YK D ++ +G+ + TD ++ K ++ S+V+Y +D+
Sbjct: 1033 DLPQFIQAKVNAYNISENMYKADLKDLSKKGYDLRTDAIPIRAAKAARQAASDVQYKKDY 1092
Query: 127 EKTKGR--GFTPVVDDPVTERVRKNTQVVSDAAYK 159
EK KG+ GF + DDP ++ SD YK
Sbjct: 1093 EKAKGKMVGFQSLQDDPKLVHYMNVAKIQSDREYK 1127
Score = 52.8 bits (125), Expect = 3e-07
Identities = 34/101 (33%), Positives = 50/101 (49%), Gaps = 2/101 (1%)
Query: 59 KQSFTTVADTPENLRLKQQSELQSQVKYKRDFEESKGRGFSIVTDTPELQRLKRTQEQIS 118
K FT+V DTP+ LR K+ +LQSQ Y + + T L+ K ++ +S
Sbjct: 5169 KSIFTSVPDTPDLLRAKRGQKLQSQYLYV-ELATKERPHHHAGNQTTALKHAKDVKDMVS 5227
Query: 119 NVKYHEDFEKTKGRGFTPVVDDPVTERVRKNTQVVSDAAYK 159
KY +EK K + +TPV D P+ R ++ SD YK
Sbjct: 5228 EKKYKIQYEKMKDK-YTPVPDTPILIRAKRAYWNASDLRYK 5267
Score = 52.4 bits (124), Expect = 4e-07
Identities = 31/99 (31%), Positives = 51/99 (51%), Gaps = 5/99 (5%)
Query: 66 ADTP--ENLRLKQQSELQSQVKYKRDFEESKGRGFSIVTDTPELQRLKRTQEQISNVKYH 123
++TP E + ++ S KY+ DFE K + + + T+TPE + K+ S VKY
Sbjct: 290 SETPCFEVANARMNADNISTRKYQEDFENMKDQIYFMQTETPEYKMNKKAGVAASKVKYK 349
Query: 124 EDFEKTKGR---GFTPVVDDPVTERVRKNTQVVSDAAYK 159
ED+EK KG+ P ++P +++ +SD YK
Sbjct: 350 EDYEKNKGKADYNVLPASENPQLRQLKAAGDALSDKLYK 388
Score = 52.4 bits (124), Expect = 4e-07
Identities = 33/111 (29%), Positives = 52/111 (46%), Gaps = 2/111 (1%)
Query: 54 NAHYPKQSFTTVADTPENLRLKQQSELQSQVKYKRDFEESKGRGFSIVTDTPELQRLKRT 113
N H K +TTV +T + R + L S YK ++ K + + + T L K
Sbjct: 4672 NYHQIKDKYTTVLETVDYDRTRNLKNLYSSNLYKEAWDRVKATSYILPSSTLSLTHAKNQ 4731
Query: 114 QEQISNVKYHEDFEKTKGRGFTP--VVDDPVTERVRKNTQVVSDAAYKGVH 162
+ S++KY E++EK K P V DDP T R + ++ D Y+ V+
Sbjct: 4732 KHLASHIKYREEYEKFKALYTLPRSVDDDPNTARCLRVGKLNIDRLYRSVY 4782
Score = 52.4 bits (124), Expect = 4e-07
Identities = 33/96 (34%), Positives = 47/96 (48%), Gaps = 10/96 (10%)
Query: 63 TTVADTPENLRLKQQSELQSQVKYKRDFEESKGRGFSIVTDTPELQRLKRTQEQISNVKY 122
T TPE R+K+ E S V YK + ++ F TPE++R+KR QE S+V Y
Sbjct: 6317 TATPVTPEMQRVKRNQENISSVLYKENLGKATPTPF-----TPEMERVKRNQENFSSVLY 6371
Query: 123 HEDFEKTKGRGFTPVVDDPVTERVRKNTQVVSDAAY 158
E+ K TP P ER ++N + +S Y
Sbjct: 6372 KENMRKA-----TPTPVTPEMERAKRNQENISSVLY 6402
Score = 52.0 bits (123), Expect = 5e-07
Identities = 31/103 (30%), Positives = 50/103 (48%), Gaps = 2/103 (1%)
Query: 59 KQSFTTVADTPENLRLKQQSELQSQVKYKRDFEESKGRGFSIVTDTPELQRLKRTQEQIS 118
K + DTP+ L+ KQ L SQ YK +EE+ +G+ + D +Q K +++ S
Sbjct: 2245 KTKIHVMPDTPDILQAKQNQTLYSQKLYKLGWEEALKKGYDLPVDAISVQLAKASRDIAS 2304
Query: 119 NVKYHEDFEKTKGR--GFTPVVDDPVTERVRKNTQVVSDAAYK 159
+ KY + + K G GF + DDP ++ S+ YK
Sbjct: 2305 DYKYKQGYRKQLGHHVGFRSLQDDPKLVLSMNVAKMQSEREYK 2347
Score = 52.0 bits (123), Expect = 5e-07
Identities = 30/96 (31%), Positives = 48/96 (50%), Gaps = 2/96 (2%)
Query: 64 TVADTPENLRLKQQSELQSQVKYKRDFEESKGRGFSIVTDTPELQRLKRTQEQISNVKYH 123
++ D PE+ + ++ S VKYK D KG G DTP+ ++ + S KY
Sbjct: 5314 SIPDRPEHFHHRAVTDTVSDVKYKEDLTWLKGIG-CYAYDTPDFTLAEKNKTLYSKYKYK 5372
Query: 124 EDFEKTKGRGFTPVVDDPVTERVRKNTQVVSDAAYK 159
E FE+TK F V D P+ + TQ++++ Y+
Sbjct: 5373 EVFERTKS-DFKYVADSPINRHFKYATQLMNEKKYR 5407
Score = 51.6 bits (122), Expect = 7e-07
Identities = 37/126 (29%), Positives = 58/126 (46%), Gaps = 3/126 (2%)
Query: 37 MALNMNNYKGYEKKPYCNA-HYPKQSFTTVADTPENLRLKQQSELQSQVKYKRDFEESKG 95
M L NN K + Y A K + D P+ + K + S YK EESK
Sbjct: 1978 MVLAQNNAKIMNEHLYKQAWEADKTKVHIMPDIPQIILAKANAINMSDKLYKLSLEESKK 2037
Query: 96 RGFSIVTDTPELQRLKRTQEQISNVKYHEDFEKTKGR--GFTPVVDDPVTERVRKNTQVV 153
+G+ + D ++ K +++ S+ KY ++EK KG+ GF + DDP + ++
Sbjct: 2038 KGYDLRPDAIPIKAAKASRDIASDYKYKYNYEKGKGKMVGFRSLEDDPKLVHSMQVAKMQ 2097
Query: 154 SDAAYK 159
SD YK
Sbjct: 2098 SDREYK 2103
Score = 50.8 bits (120), Expect = 1e-06
Identities = 37/158 (23%), Positives = 69/158 (43%), Gaps = 5/158 (3%)
Query: 59 KQSFTTVADTPENLRLKQQSELQSQVKYKRDFEESKGRGFSIVTDTPELQRLKRTQEQIS 118
K +T + P+ ++ K + S YK D++++ +G+ + D + K ++ S
Sbjct: 1513 KHKYTIDPELPQFIQAKVNALNMSDAHYKADWKKTIAKGYDLRPDAIPIVAAKSSRNIAS 1572
Query: 119 NVKYHEDFEKTKGR--GFTPVVDDPVTERVRKNTQVVSDAAYKGVHPHIVEMDRRPGIIV 176
+ KY E +EK KG+ GF + DDP ++ SD YK + P +V
Sbjct: 1573 DCKYKEAYEKAKGKQVGFLSLQDDPKLVHYMNVAKIQSDREYKKGYEASKTKYHTPLDMV 1632
Query: 177 APVLPGAYQQ---SHSQGYGYMHQTSVSSMRSMQHSPN 211
+ Q+ + + Y H T + +++HS N
Sbjct: 1633 SVTAAKKSQEVATNANYRQSYHHYTLLPDALNVEHSRN 1670
Score = 50.4 bits (119), Expect = 2e-06
Identities = 38/121 (31%), Positives = 56/121 (46%), Gaps = 6/121 (4%)
Query: 44 YKGYEKKPYCNAH----YP-KQSFTTVADTPENLRLKQQSELQSQVKYKRDFEESKGRGF 98
Y+ +K C H +P K FT V D+P L+ + S+ S + YK E K +
Sbjct: 479 YEAIKKLDQCKDHTYKVHPDKTKFTQVTDSPVLLQAQVNSKQLSDLNYKAKHESEKFK-C 537
Query: 99 SIVTDTPELQRLKRTQEQISNVKYHEDFEKTKGRGFTPVVDDPVTERVRKNTQVVSDAAY 158
I DTP + K +S+ Y +D+EK+K + F VD + NT+ SD Y
Sbjct: 538 HIPPDTPAFIQHKVNAYNLSDNLYKQDWEKSKAKKFDIKVDAIPLLAAKANTKNTSDVMY 597
Query: 159 K 159
K
Sbjct: 598 K 598
Score = 50.4 bits (119), Expect = 2e-06
Identities = 34/112 (30%), Positives = 54/112 (48%), Gaps = 2/112 (1%)
Query: 48 EKKPYCNAHYPKQSFTTVADTPENLRLKQQSELQSQVKYKRDFEESKGRGFSIVTDTPEL 107
EKK K +T V DTP +R K+ S ++YK F+++KG+ + V D ++
Sbjct: 5228 EKKYKIQYEKMKDKYTPVPDTPILIRAKRAYWNASDLRYKETFQKTKGK-YHTVKDALDI 5286
Query: 108 QRLKRTQEQISNVKYHEDFEKTKGRGFTPVVDDPVTERVRKNTQVVSDAAYK 159
++ + IS +KY E++ G + + D P R T VSD YK
Sbjct: 5287 VYHRKVTDDISKIKYKENYMSQLGI-WRSIPDRPEHFHHRAVTDTVSDVKYK 5337
Score = 50.1 bits (118), Expect = 2e-06
Identities = 37/127 (29%), Positives = 58/127 (45%), Gaps = 3/127 (2%)
Query: 36 KMALNMNNYKGYEKKPYCNA-HYPKQSFTTVADTPENLRLKQQSELQSQVKYKRDFEESK 94
++ L NN K Y A K S + DTP+ L K S SQ Y + ++ESK
Sbjct: 3679 EIVLAKNNALTMSKHLYTEAWDADKTSIHVMPDTPDILLAKSNSANISQKLYTKGWDESK 3738
Query: 95 GRGFSIVTDTPELQRLKRTQEQISNVKYHEDFEKTKGR--GFTPVVDDPVTERVRKNTQV 152
+ + + D ++ K +++ S+ KY E +EK KG G + DDP ++
Sbjct: 3739 MKDYDLRADAISIKSAKASRDIASDYKYKEAYEKQKGHHIGAQSIEDDPKIMCAIHAGKI 3798
Query: 153 VSDAAYK 159
S+ YK
Sbjct: 3799 QSEREYK 3805
Score = 50.1 bits (118), Expect = 2e-06
Identities = 37/105 (35%), Positives = 52/105 (49%), Gaps = 6/105 (5%)
Query: 31 HCEVCKMALNMNNYKGYEKKPYCNAHYPKQSFTTVADTPENLRLKQQSELQSQVKYKRDF 90
H V K M+ K Y+K N YP +F +V D PE + K S QS VKYK F
Sbjct: 4374 HVRVTKNQEMMSQIK-YKKNALEN--YP--NFRSVVDPPEIVLAKINSVNQSDVKYKETF 4428
Query: 91 EESKGRGFSIVTDTPELQRLKRTQEQISNVKYHEDFEKTKGRGFT 135
++KG+ ++ DTP + K + S + Y +E TK G+T
Sbjct: 4429 NKAKGK-YTFSPDTPHISHSKDMGKLYSTILYKGAWEGTKAYGYT 4472
Score = 49.3 bits (116), Expect = 4e-06
Identities = 25/76 (32%), Positives = 48/76 (63%), Gaps = 3/76 (3%)
Query: 60 QSFTTVADTPENLRLKQQSELQSQVKYKRDFEESKGRG-FSIV--TDTPELQRLKRTQEQ 116
Q + +TPE K+ S+VKYK D+E++KG+ ++++ ++ P+L++LK +
Sbjct: 322 QIYFMQTETPEYKMNKKAGVAASKVKYKEDYEKNKGKADYNVLPASENPQLRQLKAAGDA 381
Query: 117 ISNVKYHEDFEKTKGR 132
+S+ Y E++EKTK +
Sbjct: 382 LSDKLYKENYEKTKAK 397
Score = 49.3 bits (116), Expect = 4e-06
Identities = 31/94 (32%), Positives = 49/94 (52%), Gaps = 2/94 (2%)
Query: 67 DTPENLRLKQQSELQSQVKYKRDFEESKGRGFSIVTDTPELQRLKRTQEQISNVKYHEDF 126
D+ +++R+ + E+ SQ+KYK++ E+ F V D PE+ K S+VKY E F
Sbjct: 4370 DSVDHVRVTKNQEMMSQIKYKKNALENY-PNFRSVVDPPEIVLAKINSVNQSDVKYKETF 4428
Query: 127 EKTKGRGFTPVVDDPVTERVRKNTQVVSDAAYKG 160
K KG+ +T D P + ++ S YKG
Sbjct: 4429 NKAKGK-YTFSPDTPHISHSKDMGKLYSTILYKG 4461
Score = 48.9 bits (115), Expect = 5e-06
Identities = 30/104 (28%), Positives = 54/104 (51%), Gaps = 3/104 (2%)
Query: 60 QSFTTVADTPENLRLKQQSELQSQVKYKRDFEESKGR--GFSIVTDTPELQRLKRTQEQI 117
+ F D L K ++ S V YK+D+E+SKG+ G + D P++ +T +
Sbjct: 818 KKFDIKVDAIPLLAAKANTKNTSDVMYKKDYEKSKGKMIGALSINDDPKMLHSLKTAKNQ 877
Query: 118 SNVKYHEDFEKTKGRGFTPVVDDPVTERVRKNTQVVSDAAYKGV 161
S+ +Y +D+EK+K +T +D + +K+ + SD YK +
Sbjct: 878 SDREYRKDYEKSK-TIYTAPLDMLQVTQAKKSQAIASDVDYKHI 920
Score = 48.5 bits (114), Expect = 6e-06
Identities = 29/81 (35%), Positives = 44/81 (54%), Gaps = 4/81 (4%)
Query: 82 SQVKYKRDFEESKGRGFSIVTDTPELQRLKRTQEQISNVKYHEDFEKTKGRGFTPVVDDP 141
S YK ++EE +G+GF T T E + +K+ +Q + Y +KTK FT V D P
Sbjct: 454 SDKNYKAEYEEDRGKGFFPQTITQEYEAIKKL-DQCKDHTYKVHPDKTK---FTQVTDSP 509
Query: 142 VTERVRKNTQVVSDAAYKGVH 162
V + + N++ +SD YK H
Sbjct: 510 VLLQAQVNSKQLSDLNYKAKH 530
Score = 48.1 bits (113), Expect = 8e-06
Identities = 29/99 (29%), Positives = 51/99 (51%), Gaps = 2/99 (2%)
Query: 60 QSFTTVADTPENLRLKQQSELQSQVKYKRDFEESKGRGFSIVTDTPELQRLKRTQEQISN 119
Q + + DTPE R+K+ + S+VKY+ D + +K + +++ K+ +Q+S
Sbjct: 111 QPYASTTDTPELRRIKKVQDQLSEVKYRMDGDVAK-TICHVDEKAKDIEHAKKVSQQVSK 169
Query: 120 VKYHEDFEKTKGRGFTPVVDDPVTERVRKNTQVVSDAAY 158
V Y +++E TK + P D P + KNT + S Y
Sbjct: 170 VLYKQNWEDTKDKYLLP-PDAPELVQAVKNTAMFSKKLY 207
Score = 48.1 bits (113), Expect = 8e-06
Identities = 37/126 (29%), Positives = 54/126 (42%), Gaps = 3/126 (2%)
Query: 37 MALNMNNYKGYEKKPYCNA-HYPKQSFTTVADTPENLRLKQQSELQSQVKYKRDFEESKG 95
M L NN + Y A K + + DTPE L KQ S+ YK EE+K
Sbjct: 2708 MVLAKNNAITMNHRLYTEAWDKDKTTVHIMPDTPEVLLAKQNKVNYSEKLYKLGLEEAKR 2767
Query: 96 RGFSIVTDTPELQRLKRTQEQISNVKYHEDFEKTKGR--GFTPVVDDPVTERVRKNTQVV 153
+G+ + D ++ K +++ S KY E + K G G + DDP ++
Sbjct: 2768 KGYDMRVDAIPIKAAKASRDIASEFKYKEGYRKQLGHHIGARAIRDDPKMMWSMHVAKIQ 2827
Query: 154 SDAAYK 159
SD YK
Sbjct: 2828 SDREYK 2833
Score = 48.1 bits (113), Expect = 8e-06
Identities = 35/127 (27%), Positives = 56/127 (44%), Gaps = 3/127 (2%)
Query: 36 KMALNMNNYKGYEKKPYCNA-HYPKQSFTTVADTPENLRLKQQSELQSQVKYKRDFEESK 94
+ L NN K+ Y A K + DTPE + +Q S+ YK EE+K
Sbjct: 2950 EQVLAKNNALNMNKRLYTEAWDKDKTQIHIMPDTPEIMLARQNKINYSETLYKLANEEAK 3009
Query: 95 GRGFSIVTDTPELQRLKRTQEQISNVKYHEDFEKTKGR--GFTPVVDDPVTERVRKNTQV 152
+G+ + +D + K +++ IS+ KY + + K G G + DDP ++
Sbjct: 3010 KKGYDLRSDAIPIVAAKASRDVISDYKYKDGYRKQLGHHIGARNIEDDPKMMWSMHVAKI 3069
Query: 153 VSDAAYK 159
SD YK
Sbjct: 3070 QSDREYK 3076
Score = 48.1 bits (113), Expect = 8e-06
Identities = 37/127 (29%), Positives = 61/127 (48%), Gaps = 9/127 (7%)
Query: 59 KQSFTTVADTPENLRLKQ---QSELQSQVKYKRDFEESKGRGFSIVTDTPELQRLKRTQE 115
K+ V D E+L + S+L S +YK+ +E+SKG + + D E LK E
Sbjct: 5837 KKLHKPVTDMKESLIMNHVLNTSQLASSYQYKKKYEKSKGH-YHTIPDNLEQLHLKEATE 5895
Query: 116 QISNVKYHEDFEKTKGRGFTPVVD--DPVTERVRKNTQVVSDAAYKGVHPHIVEMDRRPG 173
S VKY E +EK +G+ P++D P +++ Q+ S Y+ + ++ G
Sbjct: 5896 LQSIVKYKEKYEKERGK---PMLDFETPTYITAKESQQMQSGKEYRKDYEESIKGRNLTG 5952
Query: 174 IIVAPVL 180
+ V P L
Sbjct: 5953 LEVTPAL 5959
Score = 47.8 bits (112), Expect = 1e-05
Identities = 42/153 (27%), Positives = 67/153 (43%), Gaps = 11/153 (7%)
Query: 10 KVVYPTEKVNCLDKYWHKGCFHCEVCKMALNMNNYKGYEKKPYCNA-HYPKQSFTTVADT 68
KV+Y + DKY + ++ + N + KK Y K F D+
Sbjct: 169 KVLYKQNWEDTKDKY----LLPPDAPELVQAVKNTAMFSKKLYTEDWEADKSLFYPYNDS 224
Query: 69 PENLRLKQQSELQSQVKYKRDFEESKGRGFSIVTDTPELQRLKRTQEQISNVKYHEDFE- 127
PE R+ Q + S V YK+ E + + F+ + D P+++ K+ Q+S KY ED+E
Sbjct: 225 PELRRVAQAQKALSDVAYKKGLAEQQAQ-FTPLADPPDIEFAKKVTNQVSKQKYKEDYEN 283
Query: 128 KTKGR-GFTPVVDDPVTERVRKNTQVVSDAAYK 159
K KG+ TP + R N +S Y+
Sbjct: 284 KIKGKWSETPCFE---VANARMNADNISTRKYQ 313
Score = 47.8 bits (112), Expect = 1e-05
Identities = 37/127 (29%), Positives = 54/127 (42%), Gaps = 3/127 (2%)
Query: 36 KMALNMNNYKGYEKKPYCNA-HYPKQSFTTVADTPENLRLKQQSELQSQVKYKRDFEESK 94
+ L NN K+ Y A K++ + DTPE + K S YK EESK
Sbjct: 3436 EQVLAKNNALNMNKRLYTEAWDNDKKTIHVMPDTPEIMLAKLNRINYSDKLYKLALEESK 3495
Query: 95 GRGFSIVTDTPELQRLKRTQEQISNVKYHEDFEKTKGR--GFTPVVDDPVTERVRKNTQV 152
G+ + D +Q K +++ S+ KY E + K G G + DDP ++
Sbjct: 3496 KEGYDLRLDAIPIQAAKASRDIASDYKYKEGYRKQLGHHIGARNIKDDPKMMWSIHVAKI 3555
Query: 153 VSDAAYK 159
SD YK
Sbjct: 3556 QSDREYK 3562
Score = 47.0 bits (110), Expect = 2e-05
Identities = 30/96 (31%), Positives = 48/96 (50%), Gaps = 4/96 (4%)
Query: 67 DTPENLRLKQQSELQSQVKYKRDFEESKGRGFSIVTDTPELQRLKRTQEQISNVKYHEDF 126
+ P + + + S YK ++EE KG+ + T T E + +K+ +Q + Y
Sbjct: 686 EDPYHTHCMKVAAQNSDKSYKAEYEEDKGKCYFPQTITQEYEAIKKL-DQCKDHTYKVHP 744
Query: 127 EKTKGRGFTPVVDDPVTERVRKNTQVVSDAAYKGVH 162
+KTK FT V D PV + + NT+ +SD YK H
Sbjct: 745 DKTK---FTAVTDSPVLLQAQLNTKQLSDLNYKAKH 777
Score = 47.0 bits (110), Expect = 2e-05
Identities = 30/87 (34%), Positives = 47/87 (54%), Gaps = 3/87 (3%)
Query: 75 KQQSELQSQVKYKRDFEESKGR--GFSIVTDTPELQRLKRTQEQISNVKYHEDFEKTKGR 132
K + S V+YK+D+E++KG+ GF + D P+L + S+ +Y +D+EKTK +
Sbjct: 1077 KAARQAASDVQYKKDYEKAKGKMVGFQSLQDDPKLVHYMNVAKIQSDREYKKDYEKTKSK 1136
Query: 133 GFTPVVDDPVTERVRKNTQVVSDAAYK 159
TP D +K VVS+ YK
Sbjct: 1137 YNTP-HDMFNVVAAKKAQDVVSNVNYK 1162
Score = 46.6 bits (109), Expect = 2e-05
Identities = 30/95 (31%), Positives = 52/95 (54%), Gaps = 2/95 (2%)
Query: 65 VADTPENLRLKQQSELQSQVKYKRDFEESKGRGFSIVTDTPELQRLKRTQEQISNVKYHE 124
V DTP+ L K+ +LQSQ++Y +E+ + +++VTDTP ++ S VKY E
Sbjct: 4613 VWDTPQILHAKKSYDLQSQLQYTAAGKENL-QNYNLVTDTPLYVTAVQSGINASEVKYKE 4671
Query: 125 DFEKTKGRGFTPVVDDPVTERVRKNTQVVSDAAYK 159
++ + K + +T V++ +R R + S YK
Sbjct: 4672 NYHQIKDK-YTTVLETVDYDRTRNLKNLYSSNLYK 4705
Score = 46.2 bits (108), Expect = 3e-05
Identities = 30/107 (28%), Positives = 55/107 (51%), Gaps = 5/107 (4%)
Query: 54 NAHYPKQSFTTVADTPENLRLKQQSELQSQVKYKRDFEE-SKGRGFSIVTDTPELQRLKR 112
N + +T + D + K ++QS YK D+ KG G+ I + +++++K+
Sbjct: 1160 NYKHSLHHYTYLPDAMDLELSKNMMQIQSDNVYKEDYNNWMKGIGW-IPIGSLDVEKVKK 1218
Query: 113 TQEQISNVKYHEDFEKTKGRGFTPVVDDPVTERVRKNTQVVSDAAYK 159
+ ++ KY + + K FT +VD PV + ++NT+ VSD YK
Sbjct: 1219 AGDALNEKKYRQHPDTLK---FTSIVDSPVMVQAKQNTKQVSDILYK 1262
Score = 46.2 bits (108), Expect = 3e-05
Identities = 36/127 (28%), Positives = 55/127 (43%), Gaps = 3/127 (2%)
Query: 36 KMALNMNNYKGYEKKPYCNA-HYPKQSFTTVADTPENLRLKQQSELQSQVKYKRDFEESK 94
+ L NN K+ Y A K + DTPE + +Q S+ Y++ EE+K
Sbjct: 3193 EQVLAKNNALNMNKRLYTEAWDKDKTQVHIMPDTPEIMLARQNKINYSESLYRQAMEEAK 3252
Query: 95 GRGFSIVTDTPELQRLKRTQEQISNVKYHEDFEKTKGR--GFTPVVDDPVTERVRKNTQV 152
G+ + +D + K +++ S+ KY E + K G G V DDP +V
Sbjct: 3253 KEGYDLRSDAIPIVAAKASRDIASDYKYKEAYRKQLGHHIGARAVHDDPKIMWSLHIAKV 3312
Query: 153 VSDAAYK 159
SD YK
Sbjct: 3313 QSDREYK 3319
Score = 46.2 bits (108), Expect = 3e-05
Identities = 45/159 (28%), Positives = 68/159 (42%), Gaps = 10/159 (6%)
Query: 10 KVVYPTEKVNCLDKYWHKGCFHCEVCKMALNMNNYKGYEKKPYCNAHYPKQSFTTVADTP 69
K VY K NC + H + K A +N Y+K+ N K + D P
Sbjct: 5513 KEVYQRNKSNCTIE---PDAVHIKAAKDAYKVNTNLDYKKQYEAN----KAHWKWTPDRP 5565
Query: 70 ENLRLKQQSELQSQVKYKRDFEESKGRGFSIVTDTPELQRLKRTQEQISNVKYHEDFEKT 129
+ L+ + S QS +YK D E KG S+ D + L+ T + S++KY E K
Sbjct: 5566 DFLQAAKSSLQQSDFEYKLDREFLKGCKLSVTDDKNTVLALRNTLIE-SDLKYKEKHVKE 5624
Query: 130 KGRGFTPVVDDPVTERVRKNTQVVSDAAYKG-VHPHIVE 167
+G V D P + + +VS+ YK V H+ +
Sbjct: 5625 RGTCHA-VPDTPQILLAKTVSNLVSENKYKDHVKKHLAQ 5662
Score = 46.2 bits (108), Expect = 3e-05
Identities = 41/165 (24%), Positives = 75/165 (45%), Gaps = 8/165 (4%)
Query: 65 VADTPENLRLKQQSELQSQVKYKRDFEESKGRG-FSIVTDTPELQRLKRTQEQISNVKYH 123
V DTP+ L K S L S+ KYK ++ +G ++ + +T + +K + +S+ Y
Sbjct: 5631 VPDTPQILLAKTVSNLVSENKYKDHVKKHLAQGSYTTLPETRDTVHVKEVTKHVSDTNYK 5690
Query: 124 EDFEKTKGR-GFTPVVDDPVTERVRKNTQVVSDAAYK---GVHPHIVEMDRRPGIIVAPV 179
+ F K KG+ ++ +++ P + + + SD AY+ + H + RP I A
Sbjct: 5691 KKFVKEKGKSNYSIMLEPPEVKHAMEVAKKQSDVAYRKDAKENLHYTTVADRPDIKKA-- 5748
Query: 180 LPGAYQQSHSQGYGYMHQTSVSSMRSMQHSPNLRTYRAMYDYSAQ 224
A +Q+ Y H+ S SM P++ + S+Q
Sbjct: 5749 -TQAAKQASEVEYRAKHRKEGSHGLSMLGRPDIEMAKKAAKLSSQ 5792
Score = 45.8 bits (107), Expect = 4e-05
Identities = 29/113 (25%), Positives = 49/113 (43%), Gaps = 5/113 (4%)
Query: 67 DTPENLRLKQQSELQSQVKYKRDFEESKGRGFSIVTDTPELQRLKRTQEQISNVKYHEDF 126
DTP +K + S KYK +E +K G+++ ++R S Y E +
Sbjct: 4966 DTPHFKHIKDTRYMSSYFKYKEAYEHTKAYGYTLGPKDVPFVHVRRVNNVTSERLYRELY 5025
Query: 127 EKTKGRGFTPVVDDPVTERVRKNTQVVSDAAYKG----VHPHIVEMDRRPGII 175
K K + T D P +V+K + VS+ YK + H++ + P +I
Sbjct: 5026 HKLKDKIHT-TPDTPEIRQVKKTQEAVSELIYKSDFFKMQGHMISLPYTPQVI 5077
Score = 44.3 bits (103), Expect = 1e-04
Identities = 28/101 (27%), Positives = 50/101 (49%), Gaps = 2/101 (1%)
Query: 62 FTTVADTPENLRLKQQSELQSQVKYKRDFEESKGRGFSIVTDTPELQRLKRTQEQISNVK 121
+T++ DTPE + K +E S KY+ +++ K I+ DTPE+ + +SN
Sbjct: 3914 YTSIVDTPEVVLAKSNAENISIPKYREVWDKDK-TSIHIMPDTPEINLARANALNVSNKL 3972
Query: 122 YHEDFEKTKGRGFTPVVDDPVTERVRKNTQVVSDAAYKGVH 162
Y E +++ K G +D + + + ++ SD YK H
Sbjct: 3973 YREGWDEMKA-GCDVRLDAIPIQAAKASREIASDYKYKLDH 4012
Score = 44.3 bits (103), Expect = 1e-04
Identities = 23/58 (39%), Positives = 34/58 (58%), Gaps = 1/58 (1%)
Query: 65 VADTPENLRLKQQSELQSQVKYKRDFEESKGRGFSIVTDTPELQRLKRTQEQISNVKY 122
V DTPE R+++ S VKY DFE+ KG +VTD P +R+K+ + S++ Y
Sbjct: 6417 VLDTPEMRRVRETQRHISTVKYHEDFEKHKGCFTPVVTD-PITERVKKNMQDFSDINY 6473
Score = 43.9 bits (102), Expect = 1e-04
Identities = 27/102 (26%), Positives = 52/102 (50%), Gaps = 4/102 (3%)
Query: 57 YPKQSFTTVADTPENLRLKQQSELQSQVKYKRDFEESKGRGFSIVTDTPELQRLKRTQEQ 116
+P +T + D + ++ ++ +LQS YK D E +G G+ + + E++++KR E
Sbjct: 3598 HPLHEWTCLPDQNDVIQARKAYDLQSDAIYKSDLEWLRGIGW-VPIGSVEVEKVKRAGEI 3656
Query: 117 ISNVKYHEDFEKTKGRGFTPVVDDPVTERVRKNTQVVSDAAY 158
+S+ KY + ++ K FT + D P + N +S Y
Sbjct: 3657 LSDRKYRQPADQLK---FTCITDTPEIVLAKNNALTMSKHLY 3695
Score = 43.5 bits (101), Expect = 2e-04
Identities = 40/171 (23%), Positives = 69/171 (40%), Gaps = 19/171 (11%)
Query: 65 VADTPENLRLKQQSELQSQVKYKRDFEESKGRGFSIVTDTPELQRLKRTQEQISNVKYHE 124
V DTPE L K +L+ +KYK +++ + +VTDTP + ++ +Q+S+ YH
Sbjct: 4858 VWDTPEILHAKHAYDLRDDIKYKAHMLKTRN-DYKLVTDTPVYVQAVKSGKQLSDAVYHY 4916
Query: 125 DFEKTKGRGFTPVVDDPVTERVRKNTQVVSDAAYK-------------GVHPHIVEMDRR 171
D+ + P +R ++ S YK G PH +
Sbjct: 4917 DYVHSVRGKVAPTTKTVDLDRALHAYKLQSSNLYKTSLRTLPTGYRLPGDTPHFKHIKDT 4976
Query: 172 PGIIVAPVLPGAYQQSHSQGYGYM---HQTSVSSMRSMQHSPNLRTYRAMY 219
+ AY+ H++ YGY +R + + + R YR +Y
Sbjct: 4977 RYMSSYFKYKEAYE--HTKAYGYTLGPKDVPFVHVRRVNNVTSERLYRELY 5025
Score = 43.1 bits (100), Expect = 3e-04
Identities = 29/111 (26%), Positives = 52/111 (46%), Gaps = 6/111 (5%)
Query: 49 KKPYCNAHYPKQSFTTVADTPENLRLKQQSELQSQVKYKRDFEESKGRGFSIVTDTPELQ 108
KK Y A F ++ D P+ + +++QS +YK+D+E++K + ++ D +
Sbjct: 1089 KKDYEKAKGKMVGFQSLQDDPKLVHYMNVAKIQSDREYKKDYEKTKSK-YNTPHDMFNVV 1147
Query: 109 RLKRTQEQISNVKYHEDFEKTKGRGFTPVVDDPVTERVRKNTQVVSDAAYK 159
K+ Q+ +SNV Y +T + D E + Q+ SD YK
Sbjct: 1148 AAKKAQDVVSNVNYKHSLHH-----YTYLPDAMDLELSKNMMQIQSDNVYK 1193
Score = 43.1 bits (100), Expect = 3e-04
Identities = 29/103 (28%), Positives = 44/103 (42%), Gaps = 2/103 (1%)
Query: 59 KQSFTTVADTPENLRLKQQSELQSQVKYKRDFEESKGRGFSIVTDTPELQRLKRTQEQIS 118
K + DTP+ + K S Y+ +EE K +G+ + D ++ K ++E S
Sbjct: 2488 KTQIHIMPDTPDIVLAKANLINTSDKLYRMGYEELKRKGYDLPVDAIPIKAAKASREIAS 2547
Query: 119 NVKYHEDFEKTKGR--GFTPVVDDPVTERVRKNTQVVSDAAYK 159
KY E F K G G + DDP ++ SD YK
Sbjct: 2548 EYKYKEGFRKQLGHHIGARNIEDDPKMMWSMHVAKIQSDREYK 2590
Score = 43.1 bits (100), Expect = 3e-04
Identities = 26/102 (25%), Positives = 44/102 (43%), Gaps = 2/102 (1%)
Query: 61 SFTTVADTPENLRLKQQSELQSQVKYKRDFEESKGRGFSIVTDTPELQRLKRTQEQISNV 120
+FT V D + + KQ E+ +KY++D+ +K + +T+TP L + +
Sbjct: 4155 NFTPVDDRVDYVTAKQSGEILDDIKYRKDWNATKSK--YTLTETPLLHTAQEAARILDQY 4212
Query: 121 KYHEDFEKTKGRGFTPVVDDPVTERVRKNTQVVSDAAYKGVH 162
Y E +E+ K G+ D V S+ YK H
Sbjct: 4213 LYKEGWERQKATGYILPPDAVPFVHAHHCNDVQSELKYKAEH 4254
Score = 42.7 bits (99), Expect = 3e-04
Identities = 30/98 (30%), Positives = 46/98 (46%), Gaps = 1/98 (1%)
Query: 62 FTTVADTPENLRLKQQSELQSQVKYKRDFEESKGRGFSIVTDTPELQRLKRTQEQISNVK 121
FT +AD P+ K+ + S+ KYK D+E +K +G T E+ + + IS K
Sbjct: 253 FTPLADPPDIEFAKKVTNQVSKQKYKEDYE-NKIKGKWSETPCFEVANARMNADNISTRK 311
Query: 122 YHEDFEKTKGRGFTPVVDDPVTERVRKNTQVVSDAAYK 159
Y EDFE K + + + P + +K S YK
Sbjct: 312 YQEDFENMKDQIYFMQTETPEYKMNKKAGVAASKVKYK 349
Score = 42.7 bits (99), Expect = 3e-04
Identities = 30/99 (30%), Positives = 49/99 (49%), Gaps = 5/99 (5%)
Query: 75 KQQSELQSQVKYKRDFEE-SKGRGFSIVTDTPELQRLKRTQEQISNVKYHEDFEKTKGRG 133
K+ LQS V+YK D+ KG G+ + + E+++ KR + ++ KY + + K
Sbjct: 937 KKAYALQSDVEYKADYNSWMKGCGW-VPFGSLEMEKAKRASDILNEKKYRQHPDTLK--- 992
Query: 134 FTPVVDDPVTERVRKNTQVVSDAAYKGVHPHIVEMDRRP 172
FT + D P+T + + N SD AYK I+ P
Sbjct: 993 FTSIEDAPITVQSKINQAQRSDIAYKAKGEEIIHKYNLP 1031
Score = 42.7 bits (99), Expect = 3e-04
Identities = 35/138 (25%), Positives = 64/138 (46%), Gaps = 21/138 (15%)
Query: 36 KMALNMNNYKGYEKKPYCNAHYPKQSFTTVADTPENLRLKQQSELQSQVKYKRDFEESKG 95
K++L + KGY+ +P D K ++ S KYK ++E+ KG
Sbjct: 2029 KLSLEESKKKGYDLRP---------------DAIPIKAAKASRDIASDYKYKYNYEKGKG 2073
Query: 96 R--GFSIVTDTPELQRLKRTQEQISNVKYHEDFEKTKGRGFTPVVDDPVTERVRKNTQV- 152
+ GF + D P+L + + S+ +Y +++E TK TP D ++ K+ Q
Sbjct: 2074 KMVGFRSLEDDPKLVHSMQVAKMQSDREYKKNYENTKTSYHTPA--DMLSVTAAKDAQAN 2131
Query: 153 VSDAAYKG-VHPHIVEMD 169
+++ YK +H +I+ D
Sbjct: 2132 ITNTNYKHLIHKYILLPD 2149
Score = 42.4 bits (98), Expect = 4e-04
Identities = 35/142 (24%), Positives = 54/142 (38%), Gaps = 14/142 (9%)
Query: 25 WHKGC-------FHCEVCKMALNMNNYKGYEKKPYCNAHYPKQSFTTVADTPENLRLKQQ 77
W KGC E K A ++ N K Y + P FT++ D P ++ K
Sbjct: 955 WMKGCGWVPFGSLEMEKAKRASDILNEKKYRQHP------DTLKFTSIEDAPITVQSKIN 1008
Query: 78 SELQSQVKYKRDFEESKGRGFSIVTDTPELQRLKRTQEQISNVKYHEDFEKTKGRGFTPV 137
+S + YK EE + +++ D P+ + K IS Y D + +G+
Sbjct: 1009 QAQRSDIAYKAKGEEIIHK-YNLPPDLPQFIQAKVNAYNISENMYKADLKDLSKKGYDLR 1067
Query: 138 VDDPVTERVRKNTQVVSDAAYK 159
D + Q SD YK
Sbjct: 1068 TDAIPIRAAKAARQAASDVQYK 1089
Score = 42.0 bits (97), Expect = 6e-04
Identities = 24/92 (26%), Positives = 48/92 (52%), Gaps = 2/92 (2%)
Query: 68 TPENLRLKQQSELQSQVKYKRDFEESKGRGFSIVTDTPELQRLKRTQEQISNVKYHEDFE 127
TP+ + + ++ S +KYK D + KG G + DTP++ R + ++ SN Y +
Sbjct: 5073 TPQVIHCRYVGDITSDIKYKEDLQVLKGFG-CFLYDTPDMVRSRHLRKLWSNYLYTDKAR 5131
Query: 128 KTKGRGFTPVVDDPVTERVRKNTQVVSDAAYK 159
K + + + V+D P +V++ +S+ Y+
Sbjct: 5132 KMRDK-YKVVLDTPEYRKVQELKTHLSELVYR 5162
Score = 41.6 bits (96), Expect = 7e-04
Identities = 29/107 (27%), Positives = 55/107 (51%), Gaps = 8/107 (7%)
Query: 60 QSFTTVADTPENLRLKQQSELQSQVKYKRDFEESKGR--GFSIVTDTPELQRLKRTQEQI 117
+ F D L K ++ S V YK+D+E++KG+ G + D P++ + +
Sbjct: 571 KKFDIKVDAIPLLAAKANTKNTSDVMYKKDYEKNKGKMIGVLSINDDPKMLHSLKVAKNQ 630
Query: 118 SNVKYHEDFEKTKGRGFTPVVDDPVTERVRKNTQV--VSDAAYKGVH 162
S+ Y E++EKTK + ++ T + + +TQ+ S+A YK ++
Sbjct: 631 SDRLYKENYEKTKAKS----MNYCETPKYQLDTQLKNFSEARYKDLY 673
Score = 41.2 bits (95), Expect = 0.001
Identities = 28/111 (25%), Positives = 51/111 (45%), Gaps = 6/111 (5%)
Query: 49 KKPYCNAHYPKQSFTTVADTPENLRLKQQSELQSQVKYKRDFEESKGRGFSIVTDTPELQ 108
K+ Y A + F ++ D P+ + +++QS +YK+ +E SK + + D +
Sbjct: 1577 KEAYEKAKGKQVGFLSLQDDPKLVHYMNVAKIQSDREYKKGYEASKTK-YHTPLDMVSVT 1635
Query: 109 RLKRTQEQISNVKYHEDFEKTKGRGFTPVVDDPVTERVRKNTQVVSDAAYK 159
K++QE +N Y + + +T + D E R Q+ SD YK
Sbjct: 1636 AAKKSQEVATNANYRQSYHH-----YTLLPDALNVEHSRNAMQIQSDNLYK 1681
Score = 40.8 bits (94), Expect = 0.001
Identities = 24/98 (24%), Positives = 46/98 (46%), Gaps = 1/98 (1%)
Query: 62 FTTVADTPENLRLKQQSELQSQVKYKRDFEESKGRGFSIVTDTPELQRLKRTQEQISNVK 121
FT++ DTPE + K + ++ Y ++ K + ++ DTPE+ K + S+
Sbjct: 3428 FTSITDTPEQVLAKNNALNMNKRLYTEAWDNDK-KTIHVMPDTPEIMLAKLNRINYSDKL 3486
Query: 122 YHEDFEKTKGRGFTPVVDDPVTERVRKNTQVVSDAAYK 159
Y E++K G+ +D + + + + SD YK
Sbjct: 3487 YKLALEESKKEGYDLRLDAIPIQAAKASRDIASDYKYK 3524
Score = 40.0 bits (92), Expect = 0.002
Identities = 30/98 (30%), Positives = 50/98 (51%), Gaps = 4/98 (4%)
Query: 62 FTTVADTPENLRLKQQSELQSQVKYKRDFEESKGRGFSIVTDTPELQRLKRTQEQISNVK 121
+T + D + ++ K+ ELQS+ YK D E +G G+S + + E ++ KR E IS K
Sbjct: 2388 WTCLPDQNDVVQAKKVYELQSENLYKSDLEWLRGIGWSPL-GSLEAEKNKRASEIISEKK 2446
Query: 122 YHEDFEKTKGRGFTPVVDDPVTERVRKNTQVVSDAAYK 159
Y + ++ K FT + D + N + SD Y+
Sbjct: 2447 YRQPPDRNK---FTSIPDAMDIVLAKTNAKNRSDRLYR 2481
Score = 40.0 bits (92), Expect = 0.002
Identities = 27/100 (27%), Positives = 47/100 (47%), Gaps = 4/100 (4%)
Query: 62 FTTVADTPENLRLKQQSELQSQVKYKRDFEESKGRGFSIVTDTPELQRLKRTQEQISNVK 121
+T + D + ++ K+ +LQS YK D E +G G+ + +PE+ R+K Q +
Sbjct: 3846 WTCMPDQNDIIQAKKAYDLQSDALYKADLEWLRGIGW-MPQGSPEVLRVKNAQNIFCDSV 3904
Query: 122 YHEDFEKTKGRGFTPVVDDPVTERVRKNTQVVSDAAYKGV 161
Y K +T +VD P + N + +S Y+ V
Sbjct: 3905 YRTPVVNLK---YTSIVDTPEVVLAKSNAENISIPKYREV 3941
Score = 39.7 bits (91), Expect = 0.003
Identities = 28/102 (27%), Positives = 47/102 (46%), Gaps = 4/102 (3%)
Query: 57 YPKQSFTTVADTPENLRLKQQSELQSQVKYKRDFEESKGRGFSIVTDTPELQRLKRTQEQ 116
+P + + D + + ++ +LQS YK D E KG G+ + D+ E+ R KR E
Sbjct: 3355 HPLHEWICLPDQNDIIHARKAYDLQSDNLYKSDLEWMKGIGW-VPIDSLEVVRAKRAGEL 3413
Query: 117 ISNVKYHEDFEKTKGRGFTPVVDDPVTERVRKNTQVVSDAAY 158
+S+ Y + E K FT + D P + N ++ Y
Sbjct: 3414 LSDTIYRQRPETLK---FTSITDTPEQVLAKNNALNMNKRLY 3452
Score = 39.3 bits (90), Expect = 0.004
Identities = 29/111 (26%), Positives = 48/111 (43%), Gaps = 6/111 (5%)
Query: 49 KKPYCNAHYPKQSFTTVADTPENLRLKQQSELQSQVKYKRDFEESKGRGFSIVTDTPELQ 108
KK Y A F ++ D P+ + Q +++QS +YK+ +E+SK F D +
Sbjct: 1821 KKAYEQAKGKHIGFRSLEDDPKLVHFMQVAKMQSDREYKKGYEKSK-TSFHTPVDMLSVV 1879
Query: 109 RLKRTQEQISNVKYHEDFEKTKGRGFTPVVDDPVTERVRKNTQVVSDAAYK 159
K++QE +N Y + + D E + Q+ SD YK
Sbjct: 1880 AAKKSQEVATNANYRNVIHT-----YNMLPDAMSFELAKNMMQIQSDNQYK 1925
Score = 39.3 bits (90), Expect = 0.004
Identities = 27/87 (31%), Positives = 42/87 (48%), Gaps = 3/87 (3%)
Query: 75 KQQSELQSQVKYKRDFEESKGR--GFSIVTDTPELQRLKRTQEQISNVKYHEDFEKTKGR 132
K ++ S KYK+ + + G GF + D P+L + S +Y +DFEK K +
Sbjct: 2297 KASRDIASDYKYKQGYRKQLGHHVGFRSLQDDPKLVLSMNVAKMQSEREYKKDFEKWKTK 2356
Query: 133 GFTPVVDDPVTERVRKNTQVVSDAAYK 159
F+ VD +K ++VSD YK
Sbjct: 2357 -FSSPVDMLGVVLAKKCQELVSDVDYK 2382
Score = 38.1 bits (87), Expect = 0.008
Identities = 27/111 (24%), Positives = 48/111 (43%), Gaps = 6/111 (5%)
Query: 49 KKPYCNAHYPKQSFTTVADTPENLRLKQQSELQSQVKYKRDFEESKGRGFSIVTDTPELQ 108
K+ Y + F ++ D P+ + ++LQS +YK+++E +K + D +
Sbjct: 1333 KEAYEKSKGKHVGFRSLQDDPKLVHYMNVAKLQSDREYKKNYENTK-TSYHTPGDMVSIT 1391
Query: 109 RLKRTQEQISNVKYHEDFEKTKGRGFTPVVDDPVTERVRKNTQVVSDAAYK 159
K Q+ +NV Y + +T + D E R Q+ SD YK
Sbjct: 1392 AAKMAQDVATNVNYKQPLHH-----YTYLPDAMSLEHTRNVNQIQSDNVYK 1437
Score = 38.1 bits (87), Expect = 0.008
Identities = 23/98 (23%), Positives = 44/98 (44%), Gaps = 1/98 (1%)
Query: 62 FTTVADTPENLRLKQQSELQSQVKYKRDFEESKGRGFSIVTDTPELQRLKRTQEQISNVK 121
FT + DTPE + K + S+ Y ++ K ++ DTP++ K IS
Sbjct: 3671 FTCITDTPEIVLAKNNALTMSKHLYTEAWDADK-TSIHVMPDTPDILLAKSNSANISQKL 3729
Query: 122 YHEDFEKTKGRGFTPVVDDPVTERVRKNTQVVSDAAYK 159
Y + ++++K + + D + + + + SD YK
Sbjct: 3730 YTKGWDESKMKDYDLRADAISIKSAKASRDIASDYKYK 3767
Score = 37.7 bits (86), Expect = 0.011
Identities = 25/92 (27%), Positives = 44/92 (47%), Gaps = 2/92 (2%)
Query: 69 PENLRLKQQSELQSQVKYKRDFEESKGRGFSIVTDTPELQR-LKRTQEQISNVKYHEDFE 127
P+ K+ ++L SQVKY+ +F++ KG+ +L + +K S VKY D +
Sbjct: 5778 PDIEMAKKAAKLSSQVKYRENFDKEKGKTPKYNPKDSQLYKVMKDANNLASEVKYKADLK 5837
Query: 128 KTKGRGFTPVVDDPVTERVRKNTQVVSDAAYK 159
K + T + + + V +Q+ S YK
Sbjct: 5838 KLH-KPVTDMKESLIMNHVLNTSQLASSYQYK 5868
Score = 37.0 bits (84), Expect = 0.018
Identities = 26/98 (26%), Positives = 45/98 (45%), Gaps = 4/98 (4%)
Query: 62 FTTVADTPENLRLKQQSELQSQVKYKRDFEESKGRGFSIVTDTPELQRLKRTQEQISNVK 121
+T + D + ++ K+ ELQS YK D E +G G+ + D+ + K + S K
Sbjct: 4088 WTCMPDQNDVIQAKKAYELQSDNVYKADLEWLRGIGW-MPNDSVSVNHAKHAADIFSEKK 4146
Query: 122 YHEDFEKTKGRGFTPVVDDPVTERVRKNTQVVSDAAYK 159
Y E FTPV D +++ +++ D Y+
Sbjct: 4147 YRTKIETL---NFTPVDDRVDYVTAKQSGEILDDIKYR 4181
Score = 36.6 bits (83), Expect = 0.024
Identities = 31/107 (28%), Positives = 48/107 (44%), Gaps = 5/107 (4%)
Query: 59 KQSFTTVADTPENLRLKQQSELQSQVKYKRDFEESKGR--GFSIVTDTPELQRLKRTQEQ 116
K+ + +D + K ++ S KYK + + G G V D P++ +
Sbjct: 3253 KEGYDLRSDAIPIVAAKASRDIASDYKYKEAYRKQLGHHIGARAVHDDPKIMWSLHIAKV 3312
Query: 117 ISNVKYHEDFEKTKGRGFTPVVDDPVTERVRKNTQVVSDAAYKGVHP 163
S+ +Y +DFEK K R +P VD +K +VSD YK HP
Sbjct: 3313 QSDREYKKDFEKYKTRYSSP-VDMLGIVLAKKCQTLVSDVDYK--HP 3356
Score = 36.2 bits (82), Expect = 0.031
Identities = 46/185 (24%), Positives = 78/185 (42%), Gaps = 12/185 (6%)
Query: 75 KQQSELQSQVKYKRDFEESKGRGFSIVTDTPELQ-RLKRTQEQISNVK-YHEDFEKTKGR 132
K E+ S KYK D E+ KG +T + + R +++ N + Y D+ K K +
Sbjct: 3997 KASREIASDYKYKLDHEKQKGHYVGTLTARDDNKIRWALIADKLQNEREYRLDWAKWKAK 4056
Query: 133 GFTPVVDDPVTERVRKNTQ-VVSDAAYKGVHPHIVEMDRRPGIIVAPVLPGAYQQSHSQG 191
+PV D ++ KN+Q +VSD Y+ M + +I A AY+
Sbjct: 4057 IQSPV--DMLSILHSKNSQALVSDMDYRNYLHQWTCMPDQNDVIQA---KKAYELQSDNV 4111
Query: 192 YGYMHQTSVSSMRSMQHSPNLRTYRAMYDYSAQDEDEVSFRDGDYIVNVQPIDDGWMYGT 251
Y + + +R + PN ++A E +R +N P+DD Y T
Sbjct: 4112 Y----KADLEWLRGIGWMPNDSVSVNHAKHAADIFSEKKYRTKIETLNFTPVDDRVDYVT 4167
Query: 252 VQRTG 256
+++G
Sbjct: 4168 AKQSG 4172
Score = 35.8 bits (81), Expect = 0.040
Identities = 27/92 (29%), Positives = 40/92 (43%), Gaps = 4/92 (4%)
Query: 68 TPENLRLKQQSELQSQVKYKRDFEESKGRGFSIVTDTPELQRLKRTQEQISNVKYHEDFE 127
+PE LR+K + Y+ K ++ + DTPE+ K E IS KY E ++
Sbjct: 3887 SPEVLRVKNAQNIFCDSVYRTPVVNLK---YTSIVDTPEVVLAKSNAENISIPKYREVWD 3943
Query: 128 KTKGRGFTPVVDDPVTERVRKNTQVVSDAAYK 159
K K + D P R N VS+ Y+
Sbjct: 3944 KDK-TSIHIMPDTPEINLARANALNVSNKLYR 3974
Score = 35.4 bits (80), Expect = 0.053
Identities = 27/98 (27%), Positives = 50/98 (51%), Gaps = 6/98 (6%)
Query: 62 FTTVADTPENLRLKQQSELQSQVKYKRDFEESKGRGFSIVTDTPELQRLKRTQEQISNVK 121
F ++ D P+ + +++QS+ +YK+DFE+ K + FS D + K+ QE +S+V
Sbjct: 2322 FRSLQDDPKLVLSMNVAKMQSEREYKKDFEKWKTK-FSSPVDMLGVVLAKKCQELVSDVD 2380
Query: 122 YHEDFEKTKGRGFTPVVDDPVTERVRKNTQVVSDAAYK 159
Y K +T + D + +K ++ S+ YK
Sbjct: 2381 Y-----KNYLHQWTCLPDQNDVVQAKKVYELQSENLYK 2413
Score = 35.4 bits (80), Expect = 0.053
Identities = 25/87 (28%), Positives = 41/87 (47%), Gaps = 3/87 (3%)
Query: 75 KQQSELQSQVKYKRDFEESKGR--GFSIVTDTPELQRLKRTQEQISNVKYHEDFEKTKGR 132
K ++ S+ KYK + + G G + D P++ + S+ +Y +DFEK K +
Sbjct: 2783 KASRDIASEFKYKEGYRKQLGHHIGARAIRDDPKMMWSMHVAKIQSDREYKKDFEKWKTK 2842
Query: 133 GFTPVVDDPVTERVRKNTQVVSDAAYK 159
F+ VD +K +VSD YK
Sbjct: 2843 -FSSPVDMLGVVLAKKCQTLVSDVDYK 2868
Score = 35.4 bits (80), Expect = 0.053
Identities = 26/85 (30%), Positives = 43/85 (50%), Gaps = 5/85 (5%)
Query: 78 SELQSQVKYKRDFEESKGR--GFSIVTDTPELQRLKRTQEQISNVKYHEDFEKTKGRGFT 135
+++QS++KYK + + KG G + D P+L + + + Y ED+ KTK +
Sbjct: 4242 NDVQSELKYKAEHVKQKGHYVGVPTMRDDPKLVWFEHAGQIQNERLYKEDYHKTKAKINI 4301
Query: 136 PVVDDPVTERVRKNTQ-VVSDAAYK 159
P D V+ K Q +VSD Y+
Sbjct: 4302 PA--DMVSVLAAKQGQTLVSDIDYR 4324
Score = 35.4 bits (80), Expect = 0.053
Identities = 27/113 (23%), Positives = 54/113 (47%), Gaps = 11/113 (9%)
Query: 47 YEKKPYCNAHYPKQSFTTVADTPENLRLKQQSELQSQVKYKRDFEESKGRGFSIVTDTPE 106
YEK+ HY + + + P + +++S + Y++ +E++K I D
Sbjct: 4499 YEKQ---KGHY--LAGKVIGEFPGVVHCLDFQKMRSALNYRKHYEDTKAN-VHIPNDMMN 4552
Query: 107 LQRLKRTQEQISNVKYHEDFEKTKGRGFTPVVDDPVTERVRKNTQVVSDAAYK 159
KR Q +S+++Y F + +T ++++P RVR +++SD YK
Sbjct: 4553 HVLAKRCQYILSDLEYRHYFHQ-----WTSLLEEPNVIRVRNAQEILSDNVYK 4600
Score = 34.3 bits (77), Expect = 0.12
Identities = 23/98 (23%), Positives = 39/98 (39%), Gaps = 2/98 (2%)
Query: 64 TVADTPENLRLKQQSELQSQVKYKRDFEESKGRGFSIVTDTPELQRLKRTQEQISNVKYH 123
T+ +TP ++ + + Q YK +E K G+ + D + S +KY
Sbjct: 4192 TLTETPLLHTAQEAARILDQYLYKEGWERQKATGYILPPDAVPFVHAHHCNDVQSELKYK 4251
Query: 124 EDFEKTKGR--GFTPVVDDPVTERVRKNTQVVSDAAYK 159
+ K KG G + DDP Q+ ++ YK
Sbjct: 4252 AEHVKQKGHYVGVPTMRDDPKLVWFEHAGQIQNERLYK 4289
Score = 34.3 bits (77), Expect = 0.12
Identities = 26/96 (27%), Positives = 45/96 (46%), Gaps = 6/96 (6%)
Query: 64 TVADTPENLRLKQQSELQSQVKYKRDFEESKGRGFSIVTDTPELQRLKRTQEQISNVKYH 123
+V D P R + +L Y+ +E++K + IV D E+ K +Q+++S + Y
Sbjct: 4756 SVDDDPNTARCLRVGKLNIDRLYRSVYEKNKMK-IHIVPDMVEMVTAKDSQKKVSEIDY- 4813
Query: 124 EDFEKTKGRGFTPVVDDPVTERVRKNTQVVSDAAYK 159
+ + + D V + VRK T +SD YK
Sbjct: 4814 ----RLRLHEWICHPDLQVNDHVRKVTDQISDIVYK 4845
Score = 33.5 bits (75), Expect = 0.20
Identities = 23/73 (31%), Positives = 34/73 (46%), Gaps = 1/73 (1%)
Query: 59 KQSFTTVADTPENLRLKQQSELQSQVKYKRDFEESKGRGFSIVTDTPELQRLKRTQEQIS 118
K S + DTPE + + S Y+ ++E K G + D +Q K ++E S
Sbjct: 3946 KTSIHIMPDTPEINLARANALNVSNKLYREGWDEMKA-GCDVRLDAIPIQAAKASREIAS 4004
Query: 119 NVKYHEDFEKTKG 131
+ KY D EK KG
Sbjct: 4005 DYKYKLDHEKQKG 4017
Score = 33.1 bits (74), Expect = 0.26
Identities = 24/104 (23%), Positives = 46/104 (44%), Gaps = 5/104 (4%)
Query: 75 KQQSELQSQVKYKRDFEESKGRGFS--IVTDTPELQRLKRTQEQISNVKYHEDFEKTKGR 132
K + S++KYK +E+ KG + ++ + P + Q+ S + Y + +E TK
Sbjct: 4484 KHADLVNSELKYKETYEKQKGHYLAGKVIGEFPGVVHCLDFQKMRSALNYRKHYEDTKAN 4543
Query: 133 GFTPVVDDPVTERVRKNTQ-VVSDAAYKGVHPHIVEMDRRPGII 175
P +D + + K Q ++SD Y+ + P +I
Sbjct: 4544 VHIP--NDMMNHVLAKRCQYILSDLEYRHYFHQWTSLLEEPNVI 4585
Score = 32.7 bits (73), Expect = 0.34
Identities = 25/95 (26%), Positives = 46/95 (48%), Gaps = 6/95 (6%)
Query: 65 VADTPENLRLKQQSELQSQVKYKRDFEESKGRGFSIVTDTPELQRLKRTQEQISNVKYHE 124
+ D P+ + +++QS +YK++FE+ K + FS D + K+ Q +S++ Y
Sbjct: 3540 IKDDPKMMWSIHVAKIQSDREYKKEFEKWKTK-FSSPVDMLGVVLAKKCQILVSDIDYKH 3598
Query: 125 DFEKTKGRGFTPVVDDPVTERVRKNTQVVSDAAYK 159
+ +T + D + RK + SDA YK
Sbjct: 3599 PLHE-----WTCLPDQNDVIQARKAYDLQSDAIYK 3628
Score = 32.3 bits (72), Expect = 0.45
Identities = 21/78 (26%), Positives = 41/78 (52%), Gaps = 4/78 (5%)
Query: 62 FTTVADTPENLRLKQQSELQSQVKYKRDFEESKGRGFSIVTDTPELQRLKRTQEQISNVK 121
+T + D + + +Q +LQS YK D + +G G+ + + ++++ KR E +S+
Sbjct: 2874 WTCLPDQSDVIHARQAYDLQSDNMYKSDLQWMRGIGW-VSIGSLDVEKCKRATEILSDKI 2932
Query: 122 YHEDFEKTKGRGFTPVVD 139
Y + ++ K FT V D
Sbjct: 2933 YRQPPDRFK---FTSVTD 2947
Score = 32.0 bits (71), Expect = 0.58
Identities = 28/115 (24%), Positives = 54/115 (46%), Gaps = 11/115 (9%)
Query: 45 KGYEKKPYCNAHYPKQSFTTVADTPENLRLKQQSELQSQVKYKRDFEESKGRGFSIVTDT 104
+ YEK+ H QS + D P+ + ++QS+ +YK++F++ K + FS D
Sbjct: 3768 EAYEKQK--GHHIGAQS---IEDDPKIMCAIHAGKIQSEREYKKEFQKWKTK-FSSPVDM 3821
Query: 105 PELQRLKRTQEQISNVKYHEDFEKTKGRGFTPVVDDPVTERVRKNTQVVSDAAYK 159
+ K+ Q ++++ Y + +T + D + +K + SDA YK
Sbjct: 3822 LSILLAKKCQTLVTDIDYRNYLHE-----WTCMPDQNDIIQAKKAYDLQSDALYK 3871
Score = 32.0 bits (71), Expect = 0.58
Identities = 34/160 (21%), Positives = 59/160 (36%), Gaps = 37/160 (23%)
Query: 31 HCEVCKMALNMNNYKGYEKKPYCNAHYPKQSFTTVADTPENLRLKQQSELQSQVKYKRDF 90
H C + YK K HY T+ D P+ + + ++Q++ YK D+
Sbjct: 4237 HAHHCNDVQSELKYKAEHVKQ--KGHYV--GVPTMRDDPKLVWFEHAGQIQNERLYKEDY 4292
Query: 91 EESKGRGFSIVTDTPELQRLKRTQEQISNVKYHE-------------------------- 124
++K + +I D + K+ Q +S++ Y
Sbjct: 4293 HKTKAK-INIPADMVSVLAAKQGQTLVSDIDYRNYLHQWMCHPDQNDVIQARKAYDLQSD 4351
Query: 125 -----DFEKTKGRGFTPVVDDPVTERVRKNTQVVSDAAYK 159
D E +G G+ P +D RV KN +++S YK
Sbjct: 4352 NVYRADLEWLRGIGWIP-LDSVDHVRVTKNQEMMSQIKYK 4390
Score = 31.6 bits (70), Expect = 0.76
Identities = 26/95 (27%), Positives = 44/95 (46%), Gaps = 6/95 (6%)
Query: 65 VADTPENLRLKQQSELQSQVKYKRDFEESKGRGFSIVTDTPELQRLKRTQEQISNVKYHE 124
+ D P+ + +++QS +YK+DFE+ K + FS D + K+ Q +S+V Y
Sbjct: 2568 IEDDPKMMWSMHVAKIQSDREYKKDFEKWKTK-FSSPVDMLGVVLAKKCQTLVSDVDY-- 2624
Query: 125 DFEKTKGRGFTPVVDDPVTERVRKNTQVVSDAAYK 159
K +T + D R+ + SD YK
Sbjct: 2625 ---KNYLHQWTCLPDQSDVIHARQAYDLQSDNLYK 2656
Score = 31.6 bits (70), Expect = 0.76
Identities = 26/95 (27%), Positives = 44/95 (46%), Gaps = 6/95 (6%)
Query: 65 VADTPENLRLKQQSELQSQVKYKRDFEESKGRGFSIVTDTPELQRLKRTQEQISNVKYHE 124
+ D P+ + +++QS +YK+DFE+ K + FS D + K+ Q +S+V Y
Sbjct: 2811 IRDDPKMMWSMHVAKIQSDREYKKDFEKWKTK-FSSPVDMLGVVLAKKCQTLVSDVDY-- 2867
Query: 125 DFEKTKGRGFTPVVDDPVTERVRKNTQVVSDAAYK 159
K +T + D R+ + SD YK
Sbjct: 2868 ---KNYLHQWTCLPDQSDVIHARQAYDLQSDNMYK 2899
Score = 31.2 bits (69), Expect = 1.00
Identities = 26/95 (27%), Positives = 44/95 (46%), Gaps = 6/95 (6%)
Query: 65 VADTPENLRLKQQSELQSQVKYKRDFEESKGRGFSIVTDTPELQRLKRTQEQISNVKYHE 124
+ D P+ + +++QS +YK+DFE+ K + FS D + K+ Q +S+V Y
Sbjct: 3054 IEDDPKMMWSMHVAKIQSDREYKKDFEKWKTK-FSSPVDMLGVVLAKKCQTLVSDVDY-- 3110
Query: 125 DFEKTKGRGFTPVVDDPVTERVRKNTQVVSDAAYK 159
K +T + D R+ + SD YK
Sbjct: 3111 ---KNYLHEWTCLPDQNDVIHARQAYDLQSDNIYK 3142
Score = 31.2 bits (69), Expect = 1.00
Identities = 22/86 (25%), Positives = 40/86 (46%), Gaps = 4/86 (4%)
Query: 73 RLKQQSELQSQVKYKRDFEESKGRGFSIVTDTPELQRLKRTQEQISNVKYHEDFEKTKGR 132
++K+ E+ S KY++ ++ K F+ +TDTPE+ K +S Y E ++ K
Sbjct: 3649 KVKRAGEILSDRKYRQPADQLK---FTCITDTPEIVLAKNNALTMSKHLYTEAWDADK-T 3704
Query: 133 GFTPVVDDPVTERVRKNTQVVSDAAY 158
+ D P + N+ +S Y
Sbjct: 3705 SIHVMPDTPDILLAKSNSANISQKLY 3730
Score = 30.8 bits (68), Expect = 1.3
Identities = 22/78 (28%), Positives = 40/78 (51%), Gaps = 4/78 (5%)
Query: 62 FTTVADTPENLRLKQQSELQSQVKYKRDFEESKGRGFSIVTDTPELQRLKRTQEQISNVK 121
+T + D + + +Q +LQS YK D + +G G+ + + ++ + KR E +S+
Sbjct: 3117 WTCLPDQNDVIHARQAYDLQSDNIYKSDLQWLRGIGW-VPIGSMDVVKCKRAAEILSDNI 3175
Query: 122 YHEDFEKTKGRGFTPVVD 139
Y + +K K FT V D
Sbjct: 3176 YRQPPDKLK---FTSVTD 3190
Score = 29.6 bits (65), Expect = 2.9
Identities = 19/74 (25%), Positives = 39/74 (52%), Gaps = 1/74 (1%)
Query: 49 KKPYCNAHYPKQSFTTVADTPENLRLKQQSELQSQVKYKRDFEESKGRGFSIVTDTPELQ 108
KK Y + ++ D P+ L + ++ QS +Y++D+E+SK ++ D ++
Sbjct: 845 KKDYEKSKGKMIGALSINDDPKMLHSLKTAKNQSDREYRKDYEKSK-TIYTAPLDMLQVT 903
Query: 109 RLKRTQEQISNVKY 122
+ K++Q S+V Y
Sbjct: 904 QAKKSQAIASDVDY 917
Score = 28.9 bits (63), Expect = 4.9
Identities = 26/97 (26%), Positives = 41/97 (42%), Gaps = 5/97 (5%)
Query: 70 ENLRLKQQSELQ---SQVKYKRDFEESKGRGFSIVTDTPELQRLKRTQEQISNVKYHEDF 126
E + K + LQ S KYK + + + + P + Q S+ Y ++
Sbjct: 403 ETPKFKLDTVLQNFSSDKKYKDSYLKDILGHYVGSFEDPYHSHCMKVTAQNSDKNYKAEY 462
Query: 127 EKTKGRGFTPVVDDPVTERVRKNTQVVSDAAYKGVHP 163
E+ +G+GF P E ++K Q D YK VHP
Sbjct: 463 EEDRGKGFFPQTITQEYEAIKKLDQ-CKDHTYK-VHP 497
Score = 28.5 bits (62), Expect = 6.5
Identities = 22/97 (22%), Positives = 47/97 (48%), Gaps = 4/97 (4%)
Query: 62 FTTVADTPENLRLKQQSELQSQVKYKRDFEESKGRGFSIVTDTPELQRLKRTQEQISNVK 121
+T + D + + +Q +LQS YK D + KG G+ + + + E ++ KR + +S+
Sbjct: 2631 WTCLPDQSDVIHARQAYDLQSDNLYKSDLQWLKGIGW-MTSGSLEDEKNKRATQILSDHV 2689
Query: 122 YHEDFEKTKGRGFTPVVDDPVTERVRKNTQVVSDAAY 158
Y + ++ K F+ ++D + N ++ Y
Sbjct: 2690 YRQHPDQFK---FSSLMDSIPMVLAKNNAITMNHRLY 2723
>gi|155030230 sorbin and SH3 domain containing 3 isoform 1 [Homo
sapiens]
Length = 671
Score = 62.8 bits (151), Expect = 3e-10
Identities = 32/80 (40%), Positives = 44/80 (55%), Gaps = 2/80 (2%)
Query: 187 SHSQGYGYMHQTSVSSMRSMQHSPNLRTYRAMYDYSAQDEDEVSFRDGDYIVNVQPIDDG 246
SHS+G + SS + Q + YRAMY Y Q+EDE+ R+GD + +Q DDG
Sbjct: 591 SHSRGPSHPLDLGTSSPNTSQI--HWTPYRAMYQYRPQNEDELELREGDRVDVMQQCDDG 648
Query: 247 WMYGTVQRTGRTGMLPANYI 266
W G +RT + G P NY+
Sbjct: 649 WFVGVSRRTQKFGTFPGNYV 668
Score = 46.6 bits (109), Expect = 2e-05
Identities = 18/51 (35%), Positives = 32/51 (62%)
Query: 217 AMYDYSAQDEDEVSFRDGDYIVNVQPIDDGWMYGTVQRTGRTGMLPANYIE 267
A Y + E E+SFR G++I ++ +++ W G + TGR G+ PA+Y++
Sbjct: 461 AQYTFKGDLEVELSFRKGEHICLIRKVNENWYEGRITGTGRQGIFPASYVQ 511
Score = 42.0 bits (97), Expect = 6e-04
Identities = 18/52 (34%), Positives = 30/52 (57%), Gaps = 2/52 (3%)
Query: 216 RAMYDYSAQDEDEVSFRDGDYIVNVQPIDDGWMYGTVQRTGRTGMLPANYIE 267
R +D+ AQ E++ + GD + + +D W+ G + GR G+ PANY+E
Sbjct: 386 RLKFDFQAQSPKELTLQKGDIVYIHKEVDKNWLEG--EHHGRLGIFPANYVE 435
>gi|65301112 sorbin and SH3 domain containing 3 isoform 2 [Homo
sapiens]
Length = 329
Score = 62.8 bits (151), Expect = 3e-10
Identities = 32/80 (40%), Positives = 44/80 (55%), Gaps = 2/80 (2%)
Query: 187 SHSQGYGYMHQTSVSSMRSMQHSPNLRTYRAMYDYSAQDEDEVSFRDGDYIVNVQPIDDG 246
SHS+G + SS + Q + YRAMY Y Q+EDE+ R+GD + +Q DDG
Sbjct: 249 SHSRGPSHPLDLGTSSPNTSQI--HWTPYRAMYQYRPQNEDELELREGDRVDVMQQCDDG 306
Query: 247 WMYGTVQRTGRTGMLPANYI 266
W G +RT + G P NY+
Sbjct: 307 WFVGVSRRTQKFGTFPGNYV 326
Score = 46.6 bits (109), Expect = 2e-05
Identities = 18/51 (35%), Positives = 32/51 (62%)
Query: 217 AMYDYSAQDEDEVSFRDGDYIVNVQPIDDGWMYGTVQRTGRTGMLPANYIE 267
A Y + E E+SFR G++I ++ +++ W G + TGR G+ PA+Y++
Sbjct: 119 AQYTFKGDLEVELSFRKGEHICLIRKVNENWYEGRITGTGRQGIFPASYVQ 169
Score = 42.0 bits (97), Expect = 6e-04
Identities = 18/52 (34%), Positives = 30/52 (57%), Gaps = 2/52 (3%)
Query: 216 RAMYDYSAQDEDEVSFRDGDYIVNVQPIDDGWMYGTVQRTGRTGMLPANYIE 267
R +D+ AQ E++ + GD + + +D W+ G + GR G+ PANY+E
Sbjct: 44 RLKFDFQAQSPKELTLQKGDIVYIHKEVDKNWLEG--EHHGRLGIFPANYVE 93
>gi|78000165 sorbin and SH3 domain containing 1 isoform 4 [Homo
sapiens]
Length = 1151
Score = 62.8 bits (151), Expect = 3e-10
Identities = 34/86 (39%), Positives = 50/86 (58%), Gaps = 7/86 (8%)
Query: 182 GAYQQSHSQGYGYMHQTSVSSMRSMQHSPNLRTYRAMYDYSAQDEDEVSFRDGDYIVNVQ 241
G QQ +Q Q V+ RS Q S +L +Y+A+Y Y Q++DE+ RDGD + ++
Sbjct: 1069 GGSQQPQAQ------QRRVTPDRS-QTSQDLFSYQALYSYIPQNDDELELRDGDIVDVME 1121
Query: 242 PIDDGWMYGTVQRTGRTGMLPANYIE 267
DDGW GT +RT + G P NY++
Sbjct: 1122 KCDDGWFVGTSRRTKQFGTFPGNYVK 1147
Score = 42.4 bits (98), Expect = 4e-04
Identities = 24/91 (26%), Positives = 43/91 (47%), Gaps = 4/91 (4%)
Query: 179 VLPGAYQQSHSQGYGYMHQTSVSSMRSMQHSPNLRTYRAMYDYSAQDEDEVSFRDGDYIV 238
V+P +Q ++ +G + ++ + +R RA +D+ AQ E+ + GD +
Sbjct: 786 VIPTHHQFITNERFGDL--LNIDDTAKRKSGSEMRPARAKFDFKAQTLKELPLQKGDIVY 843
Query: 239 NVQPIDDGWMYGTVQRTGRTGMLPANYIEFV 269
+ ID W G + GR G+ P YIE +
Sbjct: 844 IYKQIDQNWYEG--EHHGRVGIFPRTYIELL 872
Score = 42.0 bits (97), Expect = 6e-04
Identities = 15/53 (28%), Positives = 31/53 (58%)
Query: 217 AMYDYSAQDEDEVSFRDGDYIVNVQPIDDGWMYGTVQRTGRTGMLPANYIEFV 269
A ++++ + E+SFR G+ I ++ +D+ W G + T R G+ P Y++ +
Sbjct: 896 AKFNFNGDTQVEMSFRKGERITLLRQVDENWYEGRIPGTSRQGIFPITYVDVI 948
>gi|78000163 sorbin and SH3 domain containing 1 isoform 3 [Homo
sapiens]
Length = 1292
Score = 62.8 bits (151), Expect = 3e-10
Identities = 34/86 (39%), Positives = 50/86 (58%), Gaps = 7/86 (8%)
Query: 182 GAYQQSHSQGYGYMHQTSVSSMRSMQHSPNLRTYRAMYDYSAQDEDEVSFRDGDYIVNVQ 241
G QQ +Q Q V+ RS Q S +L +Y+A+Y Y Q++DE+ RDGD + ++
Sbjct: 1210 GGSQQPQAQ------QRRVTPDRS-QTSQDLFSYQALYSYIPQNDDELELRDGDIVDVME 1262
Query: 242 PIDDGWMYGTVQRTGRTGMLPANYIE 267
DDGW GT +RT + G P NY++
Sbjct: 1263 KCDDGWFVGTSRRTKQFGTFPGNYVK 1288
Score = 42.4 bits (98), Expect = 4e-04
Identities = 24/91 (26%), Positives = 43/91 (47%), Gaps = 4/91 (4%)
Query: 179 VLPGAYQQSHSQGYGYMHQTSVSSMRSMQHSPNLRTYRAMYDYSAQDEDEVSFRDGDYIV 238
V+P +Q ++ +G + ++ + +R RA +D+ AQ E+ + GD +
Sbjct: 764 VIPTHHQFITNERFGDL--LNIDDTAKRKSGSEMRPARAKFDFKAQTLKELPLQKGDIVY 821
Query: 239 NVQPIDDGWMYGTVQRTGRTGMLPANYIEFV 269
+ ID W G + GR G+ P YIE +
Sbjct: 822 IYKQIDQNWYEG--EHHGRVGIFPRTYIELL 850
Score = 42.0 bits (97), Expect = 6e-04
Identities = 15/53 (28%), Positives = 31/53 (58%)
Query: 217 AMYDYSAQDEDEVSFRDGDYIVNVQPIDDGWMYGTVQRTGRTGMLPANYIEFV 269
A ++++ + E+SFR G+ I ++ +D+ W G + T R G+ P Y++ +
Sbjct: 874 AKFNFNGDTQVEMSFRKGERITLLRQVDENWYEGRIPGTSRQGIFPITYVDVI 926
>gi|78000171 sorbin and SH3 domain containing 1 isoform 7 [Homo
sapiens]
Length = 740
Score = 62.0 bits (149), Expect = 5e-10
Identities = 30/71 (42%), Positives = 45/71 (63%), Gaps = 1/71 (1%)
Query: 197 QTSVSSMRSMQHSPNLRTYRAMYDYSAQDEDEVSFRDGDYIVNVQPIDDGWMYGTVQRTG 256
Q V+ RS Q S +L +Y+A+Y Y Q++DE+ RDGD + ++ DDGW GT +RT
Sbjct: 667 QRRVTPDRS-QTSQDLFSYQALYSYIPQNDDELELRDGDIVDVMEKCDDGWFVGTSRRTK 725
Query: 257 RTGMLPANYIE 267
+ G P NY++
Sbjct: 726 QFGTFPGNYVK 736
Score = 42.4 bits (98), Expect = 4e-04
Identities = 24/91 (26%), Positives = 43/91 (47%), Gaps = 4/91 (4%)
Query: 179 VLPGAYQQSHSQGYGYMHQTSVSSMRSMQHSPNLRTYRAMYDYSAQDEDEVSFRDGDYIV 238
V+P +Q ++ +G + ++ + +R RA +D+ AQ E+ + GD +
Sbjct: 470 VIPTHHQFITNERFGDL--LNIDDTAKRKSGSEMRPARAKFDFKAQTLKELPLQKGDIVY 527
Query: 239 NVQPIDDGWMYGTVQRTGRTGMLPANYIEFV 269
+ ID W G + GR G+ P YIE +
Sbjct: 528 IYKQIDQNWYEG--EHHGRVGIFPRTYIELL 556
Score = 42.0 bits (97), Expect = 6e-04
Identities = 15/53 (28%), Positives = 31/53 (58%)
Query: 217 AMYDYSAQDEDEVSFRDGDYIVNVQPIDDGWMYGTVQRTGRTGMLPANYIEFV 269
A ++++ + E+SFR G+ I ++ +D+ W G + T R G+ P Y++ +
Sbjct: 580 AKFNFNGDTQVEMSFRKGERITLLRQVDENWYEGRIPGTSRQGIFPITYVDVI 632
>gi|78000169 sorbin and SH3 domain containing 1 isoform 6 [Homo
sapiens]
Length = 781
Score = 62.0 bits (149), Expect = 5e-10
Identities = 30/71 (42%), Positives = 45/71 (63%), Gaps = 1/71 (1%)
Query: 197 QTSVSSMRSMQHSPNLRTYRAMYDYSAQDEDEVSFRDGDYIVNVQPIDDGWMYGTVQRTG 256
Q V+ RS Q S +L +Y+A+Y Y Q++DE+ RDGD + ++ DDGW GT +RT
Sbjct: 708 QRRVTPDRS-QTSQDLFSYQALYSYIPQNDDELELRDGDIVDVMEKCDDGWFVGTSRRTK 766
Query: 257 RTGMLPANYIE 267
+ G P NY++
Sbjct: 767 QFGTFPGNYVK 777
Score = 42.4 bits (98), Expect = 4e-04
Identities = 24/91 (26%), Positives = 43/91 (47%), Gaps = 4/91 (4%)
Query: 179 VLPGAYQQSHSQGYGYMHQTSVSSMRSMQHSPNLRTYRAMYDYSAQDEDEVSFRDGDYIV 238
V+P +Q ++ +G + ++ + +R RA +D+ AQ E+ + GD +
Sbjct: 511 VIPTHHQFITNERFGDL--LNIDDTAKRKSGSEMRPARAKFDFKAQTLKELPLQKGDIVY 568
Query: 239 NVQPIDDGWMYGTVQRTGRTGMLPANYIEFV 269
+ ID W G + GR G+ P YIE +
Sbjct: 569 IYKQIDQNWYEG--EHHGRVGIFPRTYIELL 597
Score = 42.0 bits (97), Expect = 6e-04
Identities = 15/53 (28%), Positives = 31/53 (58%)
Query: 217 AMYDYSAQDEDEVSFRDGDYIVNVQPIDDGWMYGTVQRTGRTGMLPANYIEFV 269
A ++++ + E+SFR G+ I ++ +D+ W G + T R G+ P Y++ +
Sbjct: 621 AKFNFNGDTQVEMSFRKGERITLLRQVDENWYEGRIPGTSRQGIFPITYVDVI 673
>gi|78000167 sorbin and SH3 domain containing 1 isoform 5 [Homo
sapiens]
Length = 905
Score = 62.0 bits (149), Expect = 5e-10
Identities = 30/71 (42%), Positives = 45/71 (63%), Gaps = 1/71 (1%)
Query: 197 QTSVSSMRSMQHSPNLRTYRAMYDYSAQDEDEVSFRDGDYIVNVQPIDDGWMYGTVQRTG 256
Q V+ RS Q S +L +Y+A+Y Y Q++DE+ RDGD + ++ DDGW GT +RT
Sbjct: 832 QRRVTPDRS-QTSQDLFSYQALYSYIPQNDDELELRDGDIVDVMEKCDDGWFVGTSRRTK 890
Query: 257 RTGMLPANYIE 267
+ G P NY++
Sbjct: 891 QFGTFPGNYVK 901
Score = 42.4 bits (98), Expect = 4e-04
Identities = 24/91 (26%), Positives = 43/91 (47%), Gaps = 4/91 (4%)
Query: 179 VLPGAYQQSHSQGYGYMHQTSVSSMRSMQHSPNLRTYRAMYDYSAQDEDEVSFRDGDYIV 238
V+P +Q ++ +G + ++ + +R RA +D+ AQ E+ + GD +
Sbjct: 615 VIPTHHQFITNERFGDL--LNIDDTAKRKSGSEMRPARAKFDFKAQTLKELPLQKGDIVY 672
Query: 239 NVQPIDDGWMYGTVQRTGRTGMLPANYIEFV 269
+ ID W G + GR G+ P YIE +
Sbjct: 673 IYKQIDQNWYEG--EHHGRVGIFPRTYIELL 701
Score = 42.0 bits (97), Expect = 6e-04
Identities = 15/53 (28%), Positives = 31/53 (58%)
Query: 217 AMYDYSAQDEDEVSFRDGDYIVNVQPIDDGWMYGTVQRTGRTGMLPANYIEFV 269
A ++++ + E+SFR G+ I ++ +D+ W G + T R G+ P Y++ +
Sbjct: 725 AKFNFNGDTQVEMSFRKGERITLLRQVDENWYEGRIPGTSRQGIFPITYVDVI 777
>gi|7661700 sorbin and SH3 domain containing 1 isoform 2 [Homo
sapiens]
Length = 816
Score = 62.0 bits (149), Expect = 5e-10
Identities = 30/71 (42%), Positives = 45/71 (63%), Gaps = 1/71 (1%)
Query: 197 QTSVSSMRSMQHSPNLRTYRAMYDYSAQDEDEVSFRDGDYIVNVQPIDDGWMYGTVQRTG 256
Q V+ RS Q S +L +Y+A+Y Y Q++DE+ RDGD + ++ DDGW GT +RT
Sbjct: 743 QRRVTPDRS-QTSQDLFSYQALYSYIPQNDDELELRDGDIVDVMEKCDDGWFVGTSRRTK 801
Query: 257 RTGMLPANYIE 267
+ G P NY++
Sbjct: 802 QFGTFPGNYVK 812
Score = 42.0 bits (97), Expect = 6e-04
Identities = 15/53 (28%), Positives = 31/53 (58%)
Query: 217 AMYDYSAQDEDEVSFRDGDYIVNVQPIDDGWMYGTVQRTGRTGMLPANYIEFV 269
A ++++ + E+SFR G+ I ++ +D+ W G + T R G+ P Y++ +
Sbjct: 656 AKFNFNGDTQVEMSFRKGERITLLRQVDENWYEGRIPGTSRQGIFPITYVDVI 708
Score = 41.6 bits (96), Expect = 7e-04
Identities = 21/67 (31%), Positives = 32/67 (47%), Gaps = 2/67 (2%)
Query: 203 MRSMQHSPNLRTYRAMYDYSAQDEDEVSFRDGDYIVNVQPIDDGWMYGTVQRTGRTGMLP 262
+R +R RA +D+ AQ E+ + GD + + ID W G + GR G+ P
Sbjct: 568 IRRRHDDKEMRPARAKFDFKAQTLKELPLQKGDIVYIYKQIDQNWYEG--EHHGRVGIFP 625
Query: 263 ANYIEFV 269
YIE +
Sbjct: 626 RTYIELL 632
>gi|78000160 sorbin and SH3 domain containing 1 isoform 1 [Homo
sapiens]
Length = 684
Score = 62.0 bits (149), Expect = 5e-10
Identities = 30/71 (42%), Positives = 45/71 (63%), Gaps = 1/71 (1%)
Query: 197 QTSVSSMRSMQHSPNLRTYRAMYDYSAQDEDEVSFRDGDYIVNVQPIDDGWMYGTVQRTG 256
Q V+ RS Q S +L +Y+A+Y Y Q++DE+ RDGD + ++ DDGW GT +RT
Sbjct: 611 QRRVTPDRS-QTSQDLFSYQALYSYIPQNDDELELRDGDIVDVMEKCDDGWFVGTSRRTK 669
Query: 257 RTGMLPANYIE 267
+ G P NY++
Sbjct: 670 QFGTFPGNYVK 680
Score = 42.0 bits (97), Expect = 6e-04
Identities = 15/53 (28%), Positives = 31/53 (58%)
Query: 217 AMYDYSAQDEDEVSFRDGDYIVNVQPIDDGWMYGTVQRTGRTGMLPANYIEFV 269
A ++++ + E+SFR G+ I ++ +D+ W G + T R G+ P Y++ +
Sbjct: 524 AKFNFNGDTQVEMSFRKGERITLLRQVDENWYEGRIPGTSRQGIFPITYVDVI 576
Score = 41.6 bits (96), Expect = 7e-04
Identities = 21/67 (31%), Positives = 32/67 (47%), Gaps = 2/67 (2%)
Query: 203 MRSMQHSPNLRTYRAMYDYSAQDEDEVSFRDGDYIVNVQPIDDGWMYGTVQRTGRTGMLP 262
+R +R RA +D+ AQ E+ + GD + + ID W G + GR G+ P
Sbjct: 436 IRRRHDDKEMRPARAKFDFKAQTLKELPLQKGDIVYIYKQIDQNWYEG--EHHGRVGIFP 493
Query: 263 ANYIEFV 269
YIE +
Sbjct: 494 RTYIELL 500
>gi|193083145 SH3 domain containing 19 isoform c [Homo sapiens]
Length = 731
Score = 60.1 bits (144), Expect = 2e-09
Identities = 25/60 (41%), Positives = 41/60 (68%), Gaps = 2/60 (3%)
Query: 210 PNLRTYRAMYDYSAQDEDEVSFRDGDYIVNVQPIDDGWMYGTVQRTGRTGMLPANYIEFV 269
P R +A+YD+ ++EDE+SF+ GD I ++ +DD WM G + G++G+ P NYI+F+
Sbjct: 671 PKGRKAKALYDFRGENEDELSFKAGDIITELESVDDDWMSGELM--GKSGIFPKNYIQFL 728
Score = 43.9 bits (102), Expect = 1e-04
Identities = 18/51 (35%), Positives = 34/51 (66%), Gaps = 2/51 (3%)
Query: 217 AMYDYSAQDEDEVSFRDGDYIVNVQPIDDGWMYGTVQRTGRTGMLPANYIE 267
A ++Y + +DE+SF +G+ I+ + +++ W G V+ GRTG+ P N++E
Sbjct: 519 ARFEYIGEQKDELSFSEGEIIILKEYVNEEWARGEVR--GRTGIFPLNFVE 567
>gi|193083143 SH3 domain containing 19 isoform b [Homo sapiens]
Length = 767
Score = 60.1 bits (144), Expect = 2e-09
Identities = 25/60 (41%), Positives = 41/60 (68%), Gaps = 2/60 (3%)
Query: 210 PNLRTYRAMYDYSAQDEDEVSFRDGDYIVNVQPIDDGWMYGTVQRTGRTGMLPANYIEFV 269
P R +A+YD+ ++EDE+SF+ GD I ++ +DD WM G + G++G+ P NYI+F+
Sbjct: 707 PKGRKAKALYDFRGENEDELSFKAGDIITELESVDDDWMSGELM--GKSGIFPKNYIQFL 764
Score = 43.9 bits (102), Expect = 1e-04
Identities = 18/51 (35%), Positives = 34/51 (66%), Gaps = 2/51 (3%)
Query: 217 AMYDYSAQDEDEVSFRDGDYIVNVQPIDDGWMYGTVQRTGRTGMLPANYIE 267
A ++Y + +DE+SF +G+ I+ + +++ W G V+ GRTG+ P N++E
Sbjct: 555 ARFEYIGEQKDELSFSEGEIIILKEYVNEEWARGEVR--GRTGIFPLNFVE 603
>gi|193083141 SH3 domain containing 19 isoform a [Homo sapiens]
Length = 790
Score = 60.1 bits (144), Expect = 2e-09
Identities = 25/60 (41%), Positives = 41/60 (68%), Gaps = 2/60 (3%)
Query: 210 PNLRTYRAMYDYSAQDEDEVSFRDGDYIVNVQPIDDGWMYGTVQRTGRTGMLPANYIEFV 269
P R +A+YD+ ++EDE+SF+ GD I ++ +DD WM G + G++G+ P NYI+F+
Sbjct: 730 PKGRKAKALYDFRGENEDELSFKAGDIITELESVDDDWMSGELM--GKSGIFPKNYIQFL 787
Score = 43.9 bits (102), Expect = 1e-04
Identities = 18/51 (35%), Positives = 34/51 (66%), Gaps = 2/51 (3%)
Query: 217 AMYDYSAQDEDEVSFRDGDYIVNVQPIDDGWMYGTVQRTGRTGMLPANYIE 267
A ++Y + +DE+SF +G+ I+ + +++ W G V+ GRTG+ P N++E
Sbjct: 578 ARFEYIGEQKDELSFSEGEIIILKEYVNEEWARGEVR--GRTGIFPLNFVE 626
>gi|20357552 cortactin isoform a [Homo sapiens]
Length = 550
Score = 58.9 bits (141), Expect = 4e-09
Identities = 35/95 (36%), Positives = 46/95 (48%), Gaps = 14/95 (14%)
Query: 185 QQSHSQGYGYMHQTSVSSMRSMQHSP-NLRTYR-----------AMYDYSAQDEDEVSFR 232
+ S QG Y + S + H P TY A+YDY A +DE+SF
Sbjct: 455 EASSQQGLAYATEAVYESAEAPGHYPAEDSTYDEYENDLGITAVALYDYQAAGDDEISFD 514
Query: 233 DGDYIVNVQPIDDGWMYGTVQRTGRTGMLPANYIE 267
D I N++ IDDGW G + GR G+ PANY+E
Sbjct: 515 PDDIITNIEMIDDGWWRGVCK--GRYGLFPANYVE 547
>gi|20357556 cortactin isoform b [Homo sapiens]
Length = 513
Score = 58.9 bits (141), Expect = 4e-09
Identities = 35/95 (36%), Positives = 46/95 (48%), Gaps = 14/95 (14%)
Query: 185 QQSHSQGYGYMHQTSVSSMRSMQHSP-NLRTYR-----------AMYDYSAQDEDEVSFR 232
+ S QG Y + S + H P TY A+YDY A +DE+SF
Sbjct: 418 EASSQQGLAYATEAVYESAEAPGHYPAEDSTYDEYENDLGITAVALYDYQAAGDDEISFD 477
Query: 233 DGDYIVNVQPIDDGWMYGTVQRTGRTGMLPANYIE 267
D I N++ IDDGW G + GR G+ PANY+E
Sbjct: 478 PDDIITNIEMIDDGWWRGVCK--GRYGLFPANYVE 510
>gi|4503047 cysteine-rich protein 1 (intestinal) [Homo sapiens]
Length = 77
Score = 57.8 bits (138), Expect = 1e-08
Identities = 23/52 (44%), Positives = 29/52 (55%)
Query: 3 PQCARCGKVVYPTEKVNCLDKYWHKGCFHCEVCKMALNMNNYKGYEKKPYCN 54
P+C +C K VY E+V L K WH+ C CE C L + +E KPYCN
Sbjct: 2 PKCPKCNKEVYFAERVTSLGKDWHRPCLKCEKCGKTLTSGGHAEHEGKPYCN 53
>gi|150010572 SH3 domain containing ring finger 3 [Homo sapiens]
Length = 882
Score = 55.8 bits (133), Expect = 4e-08
Identities = 25/69 (36%), Positives = 40/69 (57%), Gaps = 3/69 (4%)
Query: 202 SMRSMQHSPNL---RTYRAMYDYSAQDEDEVSFRDGDYIVNVQPIDDGWMYGTVQRTGRT 258
SM +++ P L YR + Y Q E E+ ++GD + + +DGW GT+QR GRT
Sbjct: 812 SMAAIRPEPKLLPRERYRVVVSYPPQSEAEIELKEGDIVFVHKKREDGWYKGTLQRNGRT 871
Query: 259 GMLPANYIE 267
G+ P +++E
Sbjct: 872 GLFPGSFVE 880
Score = 46.6 bits (109), Expect = 2e-05
Identities = 20/55 (36%), Positives = 28/55 (50%)
Query: 212 LRTYRAMYDYSAQDEDEVSFRDGDYIVNVQPIDDGWMYGTVQRTGRTGMLPANYI 266
L Y A+Y Y Q DE+ G+ ++ DGW G RTG +G+ P NY+
Sbjct: 466 LNVYLALYAYKPQKSDELELHKGEMYRVLEKCQDGWFKGASLRTGVSGVFPGNYV 520
Score = 44.7 bits (104), Expect = 9e-05
Identities = 23/78 (29%), Positives = 41/78 (52%), Gaps = 3/78 (3%)
Query: 193 GYMHQTSVSSMRSMQHSPNLRTY-RAMYDYSAQDEDEVSFRDGDYIVNVQPIDDGWMYGT 251
G + + + S +P L Y +A+Y Y ++ ++ F GD IV + +D+ W +G
Sbjct: 176 GSLRELATSRTAPAAKNPCLLPYGKALYSYEGKEPGDLKFNKGDIIVLRRKVDEQWYHGE 235
Query: 252 VQRTGRTGMLPANYIEFV 269
+ G G LPA+YI+ +
Sbjct: 236 LH--GTQGFLPASYIQCI 251
Score = 34.3 bits (77), Expect = 0.12
Identities = 21/116 (18%), Positives = 57/116 (49%), Gaps = 9/116 (7%)
Query: 157 AYKGVHPHIVEMDRRPGIIVAPVLPGAYQQSHSQG-YGYMHQTSVSSMRSMQHSPNLRTY 215
+Y+G P ++ ++ I++ + + G G++ + + ++ + H+P
Sbjct: 204 SYEGKEPGDLKFNKGDIIVLRRKVDEQWYHGELHGTQGFLPASYIQCIQPLPHAPPQG-- 261
Query: 216 RAMYDYSAQDEDE----VSFRDGDYIVNVQPIDDGWMYGTVQRTGRTGMLPANYIE 267
+A+YD+ +D+D+ ++F + + ++ +D+ W G + + G+ P Y+E
Sbjct: 262 KALYDFEMKDKDQDKDCLTFTKDEILTVLRRVDENWAEGML--GDKIGIFPLLYVE 315
>gi|171906575 drebrin-like isoform c [Homo sapiens]
Length = 439
Score = 55.5 bits (132), Expect = 5e-08
Identities = 49/198 (24%), Positives = 80/198 (40%), Gaps = 22/198 (11%)
Query: 78 SELQSQVKYKRDFEESKGRGFSIVT-DTPELQRLKRT--QEQISNVKYHEDFEKTKGRGF 134
+ LQ + R+ + K R S + +P+ +L+ Q+Q++ + H E
Sbjct: 257 ASLQESAVHPREIFKQKERAMSTTSISSPQPGKLRSPFLQKQLTQPETHFGREPAAAIS- 315
Query: 135 TPVVDDPVTERVRKNTQVVSDAAYKGVHPHIVEMD---RRPGIIVAPVLPGAYQQSHSQG 191
P D P E + A + V+ E + +P ++ + H QG
Sbjct: 316 RPRADLPAEEPAPSTPPCLVQAEEEAVYEEPPEQETFYEQPPLVQQQGAGSEHIDHHIQG 375
Query: 192 YGYMHQTSVSSMRSMQHSPNLRTYRAMYDYSAQDEDEVSFRDGDYIVNVQPIDDGWMYGT 251
G Q + RA+YDY A D+ E+SF + I ++ ID+GW G
Sbjct: 376 QGLSGQGLCA--------------RALYDYQAADDTEISFDPENLITGIEVIDEGWWRG- 420
Query: 252 VQRTGRTGMLPANYIEFV 269
G GM PANY+E +
Sbjct: 421 YGPDGHFGMFPANYVELI 438
>gi|21361670 drebrin-like isoform a [Homo sapiens]
Length = 431
Score = 55.5 bits (132), Expect = 5e-08
Identities = 52/215 (24%), Positives = 87/215 (40%), Gaps = 29/215 (13%)
Query: 68 TPENLRLKQQSEL-------QSQVKYKRDFEESKGRGFSIVT-DTPELQRLKRT--QEQI 117
+P++ +QQ E+ Q + R+ + K R S + +P+ +L+ Q+Q+
Sbjct: 232 SPQSRTWEQQQEVVSRNRNEQESAVHPREIFKQKERAMSTTSISSPQPGKLRSPFLQKQL 291
Query: 118 SNVKYHEDFEKTKGRGFTPVVDDPVTERVRKNTQVVSDAAYKGVHPHIVEMD---RRPGI 174
+ + H E P D P E + A + V+ E + +P +
Sbjct: 292 TQPETHFGREPAAAIS-RPRADLPAEEPAPSTPPCLVQAEEEAVYEEPPEQETFYEQPPL 350
Query: 175 IVAPVLPGAYQQSHSQGYGYMHQTSVSSMRSMQHSPNLRTYRAMYDYSAQDEDEVSFRDG 234
+ + H QG G Q + RA+YDY A D+ E+SF
Sbjct: 351 VQQQGAGSEHIDHHIQGQGLSGQGLCA--------------RALYDYQAADDTEISFDPE 396
Query: 235 DYIVNVQPIDDGWMYGTVQRTGRTGMLPANYIEFV 269
+ I ++ ID+GW G G GM PANY+E +
Sbjct: 397 NLITGIEVIDEGWWRG-YGPDGHFGMFPANYVELI 430
>gi|19224660 protein kinase C and casein kinase substrate in neurons
3 [Homo sapiens]
Length = 424
Score = 55.1 bits (131), Expect = 6e-08
Identities = 26/55 (47%), Positives = 39/55 (70%), Gaps = 2/55 (3%)
Query: 216 RAMYDYSAQDEDEVSFRDGDYIVNVQPIDD-GWMYGTVQRTGRTGMLPANYIEFV 269
RA+YDY+ Q+ DE+SFR G+ ++ + D+ GW G +Q +GR G+ PANY+E V
Sbjct: 369 RALYDYAGQEADELSFRAGEELLKMSEEDEQGWCQGQLQ-SGRIGLYPANYVECV 422
>gi|189083753 cysteine and glycine-rich protein 3 [Homo sapiens]
Length = 194
Score = 54.3 bits (129), Expect = 1e-07
Identities = 24/56 (42%), Positives = 29/56 (51%)
Query: 4 QCARCGKVVYPTEKVNCLDKYWHKGCFHCEVCKMALNMNNYKGYEKKPYCNAHYPK 59
+C RCGK VY EKV K WHK CF C +C +L N + + YC Y K
Sbjct: 119 KCPRCGKSVYAAEKVMGGGKPWHKTCFRCAICGKSLESTNVTDKDGELYCKVCYAK 174
Score = 53.9 bits (128), Expect = 1e-07
Identities = 20/57 (35%), Positives = 31/57 (54%)
Query: 4 QCARCGKVVYPTEKVNCLDKYWHKGCFHCEVCKMALNMNNYKGYEKKPYCNAHYPKQ 60
+C C K VY E++ C + +HK CFHC C+ AL+ +E + YC Y ++
Sbjct: 9 KCGACEKTVYHAEEIQCNGRSFHKTCFHCMACRKALDSTTVAAHESEIYCKVCYGRR 65
>gi|4502893 cysteine and glycine-rich protein 3 [Homo sapiens]
Length = 194
Score = 54.3 bits (129), Expect = 1e-07
Identities = 24/56 (42%), Positives = 29/56 (51%)
Query: 4 QCARCGKVVYPTEKVNCLDKYWHKGCFHCEVCKMALNMNNYKGYEKKPYCNAHYPK 59
+C RCGK VY EKV K WHK CF C +C +L N + + YC Y K
Sbjct: 119 KCPRCGKSVYAAEKVMGGGKPWHKTCFRCAICGKSLESTNVTDKDGELYCKVCYAK 174
Score = 53.9 bits (128), Expect = 1e-07
Identities = 20/57 (35%), Positives = 31/57 (54%)
Query: 4 QCARCGKVVYPTEKVNCLDKYWHKGCFHCEVCKMALNMNNYKGYEKKPYCNAHYPKQ 60
+C C K VY E++ C + +HK CFHC C+ AL+ +E + YC Y ++
Sbjct: 9 KCGACEKTVYHAEEIQCNGRSFHKTCFHCMACRKALDSTTVAAHESEIYCKVCYGRR 65
>gi|62198235 drebrin-like isoform b [Homo sapiens]
Length = 430
Score = 53.9 bits (128), Expect = 1e-07
Identities = 47/200 (23%), Positives = 82/200 (41%), Gaps = 21/200 (10%)
Query: 75 KQQSELQSQVKYKRDFEESKGRGFSIVTDTPELQRLKRT--QEQISNVKYHEDFEKTKGR 132
+ ++E +S V + F++ + + +P+ +L+ Q+Q++ + H E
Sbjct: 246 RNRNEQESAVHPREIFKQKERAMSTTSISSPQPGKLRSPFLQKQLTQPETHFGREPAAAI 305
Query: 133 GFTPVVDDPVTERVRKNTQVVSDAAYKGVHPHIVEMD---RRPGIIVAPVLPGAYQQSHS 189
P D P E + A + V+ E + +P ++ + H
Sbjct: 306 S-RPRADLPAEEPAPSTPPCLVQAEEEAVYEEPPEQETFYEQPPLVQQQGAGSEHIDHHI 364
Query: 190 QGYGYMHQTSVSSMRSMQHSPNLRTYRAMYDYSAQDEDEVSFRDGDYIVNVQPIDDGWMY 249
QG G Q + RA+YDY A D+ E+SF + I ++ ID+GW
Sbjct: 365 QGQGLSGQGLCA--------------RALYDYQAADDTEISFDPENLITGIEVIDEGWWR 410
Query: 250 GTVQRTGRTGMLPANYIEFV 269
G G GM PANY+E +
Sbjct: 411 G-YGPDGHFGMFPANYVELI 429
>gi|4503049 cysteine-rich protein 2 [Homo sapiens]
Length = 208
Score = 53.9 bits (128), Expect = 1e-07
Identities = 22/54 (40%), Positives = 30/54 (55%)
Query: 1 MNPQCARCGKVVYPTEKVNCLDKYWHKGCFHCEVCKMALNMNNYKGYEKKPYCN 54
M +C +C K VY EKV+ L K WHK C CE C L + ++ KP+C+
Sbjct: 1 MASKCPKCDKTVYFAEKVSSLGKDWHKFCLKCERCSKTLTPGGHAEHDGKPFCH 54
Score = 52.0 bits (123), Expect = 5e-07
Identities = 21/50 (42%), Positives = 27/50 (54%)
Query: 5 CARCGKVVYPTEKVNCLDKYWHKGCFHCEVCKMALNMNNYKGYEKKPYCN 54
C RC K VY EKV L K WH+ C CE C L + ++ +PYC+
Sbjct: 126 CPRCSKKVYFAEKVTSLGKDWHRPCLRCERCGKTLTPGGHAEHDGQPYCH 175
>gi|224586855 sorbin and SH3 domain containing 2 isoform 8 [Homo
sapiens]
Length = 492
Score = 53.5 bits (127), Expect = 2e-07
Identities = 39/146 (26%), Positives = 60/146 (41%), Gaps = 23/146 (15%)
Query: 122 YHEDFEKTKGRGFTPVVDDPVTERVRKNTQVVSDAAYKGVHPHIVEMDRRPGIIVAPVLP 181
Y T +G PV E V+KNT+ D + PH DR +
Sbjct: 368 YEGKIPGTNRQGIFPV---SYVEVVKKNTKGAEDYPDPPI-PHSYSSDRIHSLSSNKPQR 423
Query: 182 GAYQQSHSQGYGYMHQTSVSSMRSMQHSPNLRTYRAMYDYSAQDEDEVSFRDGDYIVNVQ 241
+ + QG G ++A+Y+Y+ ++EDE+ R+ D I ++
Sbjct: 424 PVFTHENIQGGG-------------------EPFQALYNYTPRNEDELELRESDVIDVME 464
Query: 242 PIDDGWMYGTVQRTGRTGMLPANYIE 267
DDGW GT +RT G P NY++
Sbjct: 465 KCDDGWFVGTSRRTKFFGTFPGNYVK 490
Score = 46.2 bits (108), Expect = 3e-05
Identities = 20/52 (38%), Positives = 32/52 (61%), Gaps = 2/52 (3%)
Query: 216 RAMYDYSAQDEDEVSFRDGDYIVNVQPIDDGWMYGTVQRTGRTGMLPANYIE 267
+A+YD+ AQ E+SF+ GD + ++ ID W G + GR G+ P +Y+E
Sbjct: 261 KAVYDFKAQTSKELSFKKGDTVYILRKIDQNWYEG--EHHGRVGIFPISYVE 310
Score = 45.4 bits (106), Expect = 5e-05
Identities = 18/53 (33%), Positives = 31/53 (58%)
Query: 217 AMYDYSAQDEDEVSFRDGDYIVNVQPIDDGWMYGTVQRTGRTGMLPANYIEFV 269
A Y+++A E+S R GD ++ ++ +D W G + T R G+ P +Y+E V
Sbjct: 337 AKYNFNADTNVELSLRKGDRVILLKRVDQNWYEGKIPGTNRQGIFPVSYVEVV 389
Database: hs.faa
Posted date: Aug 4, 2009 4:42 PM
Number of letters in database: 18,247,518
Number of sequences in database: 37,866
Lambda K H
0.317 0.133 0.407
Gapped
Lambda K H
0.267 0.0410 0.140
Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Hits to DB: 10,701,074
Number of Sequences: 37866
Number of extensions: 473117
Number of successful extensions: 2194
Number of sequences better than 10.0: 30
Number of HSP's better than 10.0 without gapping: 269
Number of HSP's successfully gapped in prelim test: 100
Number of HSP's that attempted gapping in prelim test: 1224
Number of HSP's gapped (non-prelim): 811
length of query: 270
length of database: 18,247,518
effective HSP length: 101
effective length of query: 169
effective length of database: 14,423,052
effective search space: 2437495788
effective search space used: 2437495788
T: 11
A: 40
X1: 16 ( 7.3 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 41 (21.7 bits)
S2: 61 (28.1 bits)
Search results were obtained with NCBI BLAST and RefSeq entries.
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Guide to the Human Genome
Copyright © 2010 by Stewart Scherer. All rights reserved.