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Search of human proteins with 46249412
BLASTP 2.2.11 [Jun-05-2005]
Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer,
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997),
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs", Nucleic Acids Res. 25:3389-3402.
Query= gi|46249412 latent transforming growth factor beta binding
protein 1 isoform LTBP-1S [Homo sapiens]
(1396 letters)
Database: hs.faa
37,866 sequences; 18,247,518 total letters
Searching..................................................done
Score E
Sequences producing significant alignments: (bits) Value
gi|46249412 latent transforming growth factor beta binding prote... 3057 0.0
gi|46249414 latent transforming growth factor beta binding prote... 3021 0.0
gi|4557733 latent transforming growth factor beta binding protei... 1078 0.0
gi|110347437 latent transforming growth factor beta binding prot... 922 0.0
gi|110347412 latent transforming growth factor beta binding prot... 904 0.0
gi|110347431 latent transforming growth factor beta binding prot... 904 0.0
gi|18497288 latent transforming growth factor beta binding prote... 832 0.0
gi|194328809 latent transforming growth factor beta binding prot... 820 0.0
gi|24430141 fibrillin 1 precursor [Homo sapiens] 552 e-157
gi|56237021 fibrillin 3 precursor [Homo sapiens] 517 e-146
gi|66346695 fibrillin 2 precursor [Homo sapiens] 472 e-133
gi|51873053 fibulin 2 isoform a precursor [Homo sapiens] 283 6e-76
gi|34734064 fibulin 1 isoform B precursor [Homo sapiens] 256 8e-68
gi|34734068 fibulin 1 isoform A precursor [Homo sapiens] 256 8e-68
gi|34734066 fibulin 1 isoform D [Homo sapiens] 256 8e-68
gi|34734062 fibulin 1 isoform C precursor [Homo sapiens] 256 8e-68
gi|51873055 fibulin 2 isoform b precursor [Homo sapiens] 249 2e-65
gi|62548862 matrilin 2 isoform b precursor [Homo sapiens] 238 3e-62
gi|62548860 matrilin 2 isoform a precursor [Homo sapiens] 238 3e-62
gi|118572606 hemicentin 1 [Homo sapiens] 237 5e-62
gi|24041035 notch 2 preproprotein [Homo sapiens] 229 1e-59
gi|134244285 Notch homolog 3 [Homo sapiens] 229 2e-59
gi|148833508 notch1 preproprotein [Homo sapiens] 221 3e-57
gi|120587029 signal peptide, CUB domain, EGF-like 1 [Homo sapiens] 219 1e-56
gi|31377568 signal peptide, CUB domain, EGF-like 3 [Homo sapiens] 204 5e-52
gi|55770876 notch4 preproprotein [Homo sapiens] 203 8e-52
gi|169178458 PREDICTED: hemicentin 2 [Homo sapiens] 203 1e-51
gi|239749684 PREDICTED: hemicentin 2 [Homo sapiens] 203 1e-51
gi|169177000 PREDICTED: hemicentin 2 [Homo sapiens] 203 1e-51
gi|10190748 CEGP1 protein [Homo sapiens] 188 3e-47
>gi|46249412 latent transforming growth factor beta binding protein 1
isoform LTBP-1S [Homo sapiens]
Length = 1396
Score = 3057 bits (7926), Expect = 0.0
Identities = 1396/1396 (100%), Positives = 1396/1396 (100%)
Query: 1 MDTKLMCLLFFFSLPPLLVSNHTGRIKVVFTPSICKVTCTKGSCQNSCEKGNTTTLISEN 60
MDTKLMCLLFFFSLPPLLVSNHTGRIKVVFTPSICKVTCTKGSCQNSCEKGNTTTLISEN
Sbjct: 1 MDTKLMCLLFFFSLPPLLVSNHTGRIKVVFTPSICKVTCTKGSCQNSCEKGNTTTLISEN 60
Query: 61 GHAADTLTATNFRVVICHLPCMNGGQCSSRDKCQCPPNFTGKLCQIPVHGASVPKLYQHS 120
GHAADTLTATNFRVVICHLPCMNGGQCSSRDKCQCPPNFTGKLCQIPVHGASVPKLYQHS
Sbjct: 61 GHAADTLTATNFRVVICHLPCMNGGQCSSRDKCQCPPNFTGKLCQIPVHGASVPKLYQHS 120
Query: 121 QQPGKALGTHVIHSTHTLPLTVTSQQGVKVKFPPNIVNIHVKHPPEASVQIHQVSRIDGP 180
QQPGKALGTHVIHSTHTLPLTVTSQQGVKVKFPPNIVNIHVKHPPEASVQIHQVSRIDGP
Sbjct: 121 QQPGKALGTHVIHSTHTLPLTVTSQQGVKVKFPPNIVNIHVKHPPEASVQIHQVSRIDGP 180
Query: 181 TGQKTKEAQPGQSQVSYQGLPVQKTQTIHSTYSHQQVIPHVYPVAAKTQLGRCFQETIGS 240
TGQKTKEAQPGQSQVSYQGLPVQKTQTIHSTYSHQQVIPHVYPVAAKTQLGRCFQETIGS
Sbjct: 181 TGQKTKEAQPGQSQVSYQGLPVQKTQTIHSTYSHQQVIPHVYPVAAKTQLGRCFQETIGS 240
Query: 241 QCGKALPGLSKQEDCCGTVGTSWGFNKCQKCPKKPSYHGYNQMMECLPGYKRVNNTFCQD 300
QCGKALPGLSKQEDCCGTVGTSWGFNKCQKCPKKPSYHGYNQMMECLPGYKRVNNTFCQD
Sbjct: 241 QCGKALPGLSKQEDCCGTVGTSWGFNKCQKCPKKPSYHGYNQMMECLPGYKRVNNTFCQD 300
Query: 301 INECQLQGVCPNGECLNTMGSYRCTCKIGFGPDPTFSSCVPDPPVISEEKGPCYRLVSSG 360
INECQLQGVCPNGECLNTMGSYRCTCKIGFGPDPTFSSCVPDPPVISEEKGPCYRLVSSG
Sbjct: 301 INECQLQGVCPNGECLNTMGSYRCTCKIGFGPDPTFSSCVPDPPVISEEKGPCYRLVSSG 360
Query: 361 RQCMHPLSVHLTKQLCCCSVGKAWGPHCEKCPLPGTAAFKEICPGGMGYTVSGVHRRRPI 420
RQCMHPLSVHLTKQLCCCSVGKAWGPHCEKCPLPGTAAFKEICPGGMGYTVSGVHRRRPI
Sbjct: 361 RQCMHPLSVHLTKQLCCCSVGKAWGPHCEKCPLPGTAAFKEICPGGMGYTVSGVHRRRPI 420
Query: 421 HHHVGKGPVFVKPKNTQPVAKSTHPPPLPAKEEPVEALTFSREHGPGVAEPEVATAPPEK 480
HHHVGKGPVFVKPKNTQPVAKSTHPPPLPAKEEPVEALTFSREHGPGVAEPEVATAPPEK
Sbjct: 421 HHHVGKGPVFVKPKNTQPVAKSTHPPPLPAKEEPVEALTFSREHGPGVAEPEVATAPPEK 480
Query: 481 EIPSLDQEKTKLEPGQPQLSPGISTIHLHPQFPGIVIEKTSPPVPVEVAPEASTSSASQV 540
EIPSLDQEKTKLEPGQPQLSPGISTIHLHPQFPGIVIEKTSPPVPVEVAPEASTSSASQV
Sbjct: 481 EIPSLDQEKTKLEPGQPQLSPGISTIHLHPQFPGIVIEKTSPPVPVEVAPEASTSSASQV 540
Query: 541 IAPTQVTEINECTVNPDICGAGHCINLPVRYTCICYEGYRFSEQQRKCVDIDECTQVQHL 600
IAPTQVTEINECTVNPDICGAGHCINLPVRYTCICYEGYRFSEQQRKCVDIDECTQVQHL
Sbjct: 541 IAPTQVTEINECTVNPDICGAGHCINLPVRYTCICYEGYRFSEQQRKCVDIDECTQVQHL 600
Query: 601 CSQGRCENTEGSFLCICPAGFMASEEGTNCIDVDECLRPDVCGEGHCVNTVGAFRCEYCD 660
CSQGRCENTEGSFLCICPAGFMASEEGTNCIDVDECLRPDVCGEGHCVNTVGAFRCEYCD
Sbjct: 601 CSQGRCENTEGSFLCICPAGFMASEEGTNCIDVDECLRPDVCGEGHCVNTVGAFRCEYCD 660
Query: 661 SGYRMTQRGRCEDIDECLNPSTCPDEQCVNSPGSYQCVPCTEGFRGWNGQCLDVDECLEP 720
SGYRMTQRGRCEDIDECLNPSTCPDEQCVNSPGSYQCVPCTEGFRGWNGQCLDVDECLEP
Sbjct: 661 SGYRMTQRGRCEDIDECLNPSTCPDEQCVNSPGSYQCVPCTEGFRGWNGQCLDVDECLEP 720
Query: 721 NVCANGDCSNLEGSYMCSCHKGYTRTPDHKHCRDIDECQQGNLCVNGQCKNTEGSFRCTC 780
NVCANGDCSNLEGSYMCSCHKGYTRTPDHKHCRDIDECQQGNLCVNGQCKNTEGSFRCTC
Sbjct: 721 NVCANGDCSNLEGSYMCSCHKGYTRTPDHKHCRDIDECQQGNLCVNGQCKNTEGSFRCTC 780
Query: 781 GQGYQLSAAKDQCEDIDECQHRHLCAHGQCRNTEGSFQCVCDQGYRASGLGDHCEDINEC 840
GQGYQLSAAKDQCEDIDECQHRHLCAHGQCRNTEGSFQCVCDQGYRASGLGDHCEDINEC
Sbjct: 781 GQGYQLSAAKDQCEDIDECQHRHLCAHGQCRNTEGSFQCVCDQGYRASGLGDHCEDINEC 840
Query: 841 LEDKSVCQRGDCINTAGSYDCTCPDGFQLDDNKTCQDINECEHPGLCGPQGECLNTEGSF 900
LEDKSVCQRGDCINTAGSYDCTCPDGFQLDDNKTCQDINECEHPGLCGPQGECLNTEGSF
Sbjct: 841 LEDKSVCQRGDCINTAGSYDCTCPDGFQLDDNKTCQDINECEHPGLCGPQGECLNTEGSF 900
Query: 901 HCVCQQGFSISADGRTCEDIDECVNNTVCDSHGFCDNTAGSFRCLCYQGFQAPQDGQGCV 960
HCVCQQGFSISADGRTCEDIDECVNNTVCDSHGFCDNTAGSFRCLCYQGFQAPQDGQGCV
Sbjct: 901 HCVCQQGFSISADGRTCEDIDECVNNTVCDSHGFCDNTAGSFRCLCYQGFQAPQDGQGCV 960
Query: 961 DVNECELLSGVCGEAFCENVEGSFLCVCADENQEYSPMTGQCRSRTSTDLDVDVDQPKEE 1020
DVNECELLSGVCGEAFCENVEGSFLCVCADENQEYSPMTGQCRSRTSTDLDVDVDQPKEE
Sbjct: 961 DVNECELLSGVCGEAFCENVEGSFLCVCADENQEYSPMTGQCRSRTSTDLDVDVDQPKEE 1020
Query: 1021 KKECYYNLNDASLCDNVLAPNVTKQECCCTSGAGWGDNCEIFPCPVLGTAEFTEMCPKGK 1080
KKECYYNLNDASLCDNVLAPNVTKQECCCTSGAGWGDNCEIFPCPVLGTAEFTEMCPKGK
Sbjct: 1021 KKECYYNLNDASLCDNVLAPNVTKQECCCTSGAGWGDNCEIFPCPVLGTAEFTEMCPKGK 1080
Query: 1081 GFVPAGESSSEAGGENYKDADECLLFGQEICKNGFCLNTRPGYECYCKQGTYYDPVKLQC 1140
GFVPAGESSSEAGGENYKDADECLLFGQEICKNGFCLNTRPGYECYCKQGTYYDPVKLQC
Sbjct: 1081 GFVPAGESSSEAGGENYKDADECLLFGQEICKNGFCLNTRPGYECYCKQGTYYDPVKLQC 1140
Query: 1141 FDMDECQDPSSCIDGQCVNTEGSYNCFCTHPMVLDASEKRCIRPAESNEQIEETDVYQDL 1200
FDMDECQDPSSCIDGQCVNTEGSYNCFCTHPMVLDASEKRCIRPAESNEQIEETDVYQDL
Sbjct: 1141 FDMDECQDPSSCIDGQCVNTEGSYNCFCTHPMVLDASEKRCIRPAESNEQIEETDVYQDL 1200
Query: 1201 CWEHLSDEYVCSRPLVGKQTTYTECCCLYGEAWGMQCALCPLKDSDDYAQLCNIPVTGRR 1260
CWEHLSDEYVCSRPLVGKQTTYTECCCLYGEAWGMQCALCPLKDSDDYAQLCNIPVTGRR
Sbjct: 1201 CWEHLSDEYVCSRPLVGKQTTYTECCCLYGEAWGMQCALCPLKDSDDYAQLCNIPVTGRR 1260
Query: 1261 QPYGRDALVDFSEQYTPEADPYFIQDRFLNSFEELQAEECGILNGCENGRCVRVQEGYTC 1320
QPYGRDALVDFSEQYTPEADPYFIQDRFLNSFEELQAEECGILNGCENGRCVRVQEGYTC
Sbjct: 1261 QPYGRDALVDFSEQYTPEADPYFIQDRFLNSFEELQAEECGILNGCENGRCVRVQEGYTC 1320
Query: 1321 DCFDGYHLDTAKMTCVDVNECDELNNRMSLCKNAKCINTDGSYKCLCLPGYVPSDKPNYC 1380
DCFDGYHLDTAKMTCVDVNECDELNNRMSLCKNAKCINTDGSYKCLCLPGYVPSDKPNYC
Sbjct: 1321 DCFDGYHLDTAKMTCVDVNECDELNNRMSLCKNAKCINTDGSYKCLCLPGYVPSDKPNYC 1380
Query: 1381 TPLNTALNLEKDSDLE 1396
TPLNTALNLEKDSDLE
Sbjct: 1381 TPLNTALNLEKDSDLE 1396
>gi|46249414 latent transforming growth factor beta binding protein 1
isoform LTBP-1L [Homo sapiens]
Length = 1722
Score = 3021 bits (7833), Expect = 0.0
Identities = 1378/1381 (99%), Positives = 1379/1381 (99%)
Query: 16 PLLVSNHTGRIKVVFTPSICKVTCTKGSCQNSCEKGNTTTLISENGHAADTLTATNFRVV 75
P +SNHTGRIKVVFTPSICKVTCTKGSCQNSCEKGNTTTLISENGHAADTLTATNFRVV
Sbjct: 342 PFQLSNHTGRIKVVFTPSICKVTCTKGSCQNSCEKGNTTTLISENGHAADTLTATNFRVV 401
Query: 76 ICHLPCMNGGQCSSRDKCQCPPNFTGKLCQIPVHGASVPKLYQHSQQPGKALGTHVIHST 135
ICHLPCMNGGQCSSRDKCQCPPNFTGKLCQIPVHGASVPKLYQHSQQPGKALGTHVIHST
Sbjct: 402 ICHLPCMNGGQCSSRDKCQCPPNFTGKLCQIPVHGASVPKLYQHSQQPGKALGTHVIHST 461
Query: 136 HTLPLTVTSQQGVKVKFPPNIVNIHVKHPPEASVQIHQVSRIDGPTGQKTKEAQPGQSQV 195
HTLPLTVTSQQGVKVKFPPNIVNIHVKHPPEASVQIHQVSRIDGPTGQKTKEAQPGQSQV
Sbjct: 462 HTLPLTVTSQQGVKVKFPPNIVNIHVKHPPEASVQIHQVSRIDGPTGQKTKEAQPGQSQV 521
Query: 196 SYQGLPVQKTQTIHSTYSHQQVIPHVYPVAAKTQLGRCFQETIGSQCGKALPGLSKQEDC 255
SYQGLPVQKTQTIHSTYSHQQVIPHVYPVAAKTQLGRCFQETIGSQCGKALPGLSKQEDC
Sbjct: 522 SYQGLPVQKTQTIHSTYSHQQVIPHVYPVAAKTQLGRCFQETIGSQCGKALPGLSKQEDC 581
Query: 256 CGTVGTSWGFNKCQKCPKKPSYHGYNQMMECLPGYKRVNNTFCQDINECQLQGVCPNGEC 315
CGTVGTSWGFNKCQKCPKKPSYHGYNQMMECLPGYKRVNNTFCQDINECQLQGVCPNGEC
Sbjct: 582 CGTVGTSWGFNKCQKCPKKPSYHGYNQMMECLPGYKRVNNTFCQDINECQLQGVCPNGEC 641
Query: 316 LNTMGSYRCTCKIGFGPDPTFSSCVPDPPVISEEKGPCYRLVSSGRQCMHPLSVHLTKQL 375
LNTMGSYRCTCKIGFGPDPTFSSCVPDPPVISEEKGPCYRLVSSGRQCMHPLSVHLTKQL
Sbjct: 642 LNTMGSYRCTCKIGFGPDPTFSSCVPDPPVISEEKGPCYRLVSSGRQCMHPLSVHLTKQL 701
Query: 376 CCCSVGKAWGPHCEKCPLPGTAAFKEICPGGMGYTVSGVHRRRPIHHHVGKGPVFVKPKN 435
CCCSVGKAWGPHCEKCPLPGTAAFKEICPGGMGYTVSGVHRRRPIHHHVGKGPVFVKPKN
Sbjct: 702 CCCSVGKAWGPHCEKCPLPGTAAFKEICPGGMGYTVSGVHRRRPIHHHVGKGPVFVKPKN 761
Query: 436 TQPVAKSTHPPPLPAKEEPVEALTFSREHGPGVAEPEVATAPPEKEIPSLDQEKTKLEPG 495
TQPVAKSTHPPPLPAKEEPVEALTFSREHGPGVAEPEVATAPPEKEIPSLDQEKTKLEPG
Sbjct: 762 TQPVAKSTHPPPLPAKEEPVEALTFSREHGPGVAEPEVATAPPEKEIPSLDQEKTKLEPG 821
Query: 496 QPQLSPGISTIHLHPQFPGIVIEKTSPPVPVEVAPEASTSSASQVIAPTQVTEINECTVN 555
QPQLSPGISTIHLHPQFPGIVIEKTSPPVPVEVAPEASTSSASQVIAPTQVTEINECTVN
Sbjct: 822 QPQLSPGISTIHLHPQFPGIVIEKTSPPVPVEVAPEASTSSASQVIAPTQVTEINECTVN 881
Query: 556 PDICGAGHCINLPVRYTCICYEGYRFSEQQRKCVDIDECTQVQHLCSQGRCENTEGSFLC 615
PDICGAGHCINLPVRYTCICYEGYRFSEQQRKCVDIDECTQVQHLCSQGRCENTEGSFLC
Sbjct: 882 PDICGAGHCINLPVRYTCICYEGYRFSEQQRKCVDIDECTQVQHLCSQGRCENTEGSFLC 941
Query: 616 ICPAGFMASEEGTNCIDVDECLRPDVCGEGHCVNTVGAFRCEYCDSGYRMTQRGRCEDID 675
ICPAGFMASEEGTNCIDVDECLRPDVCGEGHCVNTVGAFRCEYCDSGYRMTQRGRCEDID
Sbjct: 942 ICPAGFMASEEGTNCIDVDECLRPDVCGEGHCVNTVGAFRCEYCDSGYRMTQRGRCEDID 1001
Query: 676 ECLNPSTCPDEQCVNSPGSYQCVPCTEGFRGWNGQCLDVDECLEPNVCANGDCSNLEGSY 735
ECLNPSTCPDEQCVNSPGSYQCVPCTEGFRGWNGQCLDVDECLEPNVCANGDCSNLEGSY
Sbjct: 1002 ECLNPSTCPDEQCVNSPGSYQCVPCTEGFRGWNGQCLDVDECLEPNVCANGDCSNLEGSY 1061
Query: 736 MCSCHKGYTRTPDHKHCRDIDECQQGNLCVNGQCKNTEGSFRCTCGQGYQLSAAKDQCED 795
MCSCHKGYTRTPDHKHCRDIDECQQGNLCVNGQCKNTEGSFRCTCGQGYQLSAAKDQCED
Sbjct: 1062 MCSCHKGYTRTPDHKHCRDIDECQQGNLCVNGQCKNTEGSFRCTCGQGYQLSAAKDQCED 1121
Query: 796 IDECQHRHLCAHGQCRNTEGSFQCVCDQGYRASGLGDHCEDINECLEDKSVCQRGDCINT 855
IDECQHRHLCAHGQCRNTEGSFQCVCDQGYRASGLGDHCEDINECLEDKSVCQRGDCINT
Sbjct: 1122 IDECQHRHLCAHGQCRNTEGSFQCVCDQGYRASGLGDHCEDINECLEDKSVCQRGDCINT 1181
Query: 856 AGSYDCTCPDGFQLDDNKTCQDINECEHPGLCGPQGECLNTEGSFHCVCQQGFSISADGR 915
AGSYDCTCPDGFQLDDNKTCQDINECEHPGLCGPQGECLNTEGSFHCVCQQGFSISADGR
Sbjct: 1182 AGSYDCTCPDGFQLDDNKTCQDINECEHPGLCGPQGECLNTEGSFHCVCQQGFSISADGR 1241
Query: 916 TCEDIDECVNNTVCDSHGFCDNTAGSFRCLCYQGFQAPQDGQGCVDVNECELLSGVCGEA 975
TCEDIDECVNNTVCDSHGFCDNTAGSFRCLCYQGFQAPQDGQGCVDVNECELLSGVCGEA
Sbjct: 1242 TCEDIDECVNNTVCDSHGFCDNTAGSFRCLCYQGFQAPQDGQGCVDVNECELLSGVCGEA 1301
Query: 976 FCENVEGSFLCVCADENQEYSPMTGQCRSRTSTDLDVDVDQPKEEKKECYYNLNDASLCD 1035
FCENVEGSFLCVCADENQEYSPMTGQCRSRTSTDLDVDVDQPKEEKKECYYNLNDASLCD
Sbjct: 1302 FCENVEGSFLCVCADENQEYSPMTGQCRSRTSTDLDVDVDQPKEEKKECYYNLNDASLCD 1361
Query: 1036 NVLAPNVTKQECCCTSGAGWGDNCEIFPCPVLGTAEFTEMCPKGKGFVPAGESSSEAGGE 1095
NVLAPNVTKQECCCTSGAGWGDNCEIFPCPVLGTAEFTEMCPKGKGFVPAGESSSEAGGE
Sbjct: 1362 NVLAPNVTKQECCCTSGAGWGDNCEIFPCPVLGTAEFTEMCPKGKGFVPAGESSSEAGGE 1421
Query: 1096 NYKDADECLLFGQEICKNGFCLNTRPGYECYCKQGTYYDPVKLQCFDMDECQDPSSCIDG 1155
NYKDADECLLFGQEICKNGFCLNTRPGYECYCKQGTYYDPVKLQCFDMDECQDPSSCIDG
Sbjct: 1422 NYKDADECLLFGQEICKNGFCLNTRPGYECYCKQGTYYDPVKLQCFDMDECQDPSSCIDG 1481
Query: 1156 QCVNTEGSYNCFCTHPMVLDASEKRCIRPAESNEQIEETDVYQDLCWEHLSDEYVCSRPL 1215
QCVNTEGSYNCFCTHPMVLDASEKRCIRPAESNEQIEETDVYQDLCWEHLSDEYVCSRPL
Sbjct: 1482 QCVNTEGSYNCFCTHPMVLDASEKRCIRPAESNEQIEETDVYQDLCWEHLSDEYVCSRPL 1541
Query: 1216 VGKQTTYTECCCLYGEAWGMQCALCPLKDSDDYAQLCNIPVTGRRQPYGRDALVDFSEQY 1275
VGKQTTYTECCCLYGEAWGMQCALCPLKDSDDYAQLCNIPVTGRRQPYGRDALVDFSEQY
Sbjct: 1542 VGKQTTYTECCCLYGEAWGMQCALCPLKDSDDYAQLCNIPVTGRRQPYGRDALVDFSEQY 1601
Query: 1276 TPEADPYFIQDRFLNSFEELQAEECGILNGCENGRCVRVQEGYTCDCFDGYHLDTAKMTC 1335
TPEADPYFIQDRFLNSFEELQAEECGILNGCENGRCVRVQEGYTCDCFDGYHLDTAKMTC
Sbjct: 1602 TPEADPYFIQDRFLNSFEELQAEECGILNGCENGRCVRVQEGYTCDCFDGYHLDTAKMTC 1661
Query: 1336 VDVNECDELNNRMSLCKNAKCINTDGSYKCLCLPGYVPSDKPNYCTPLNTALNLEKDSDL 1395
VDVNECDELNNRMSLCKNAKCINTDGSYKCLCLPGYVPSDKPNYCTPLNTALNLEKDSDL
Sbjct: 1662 VDVNECDELNNRMSLCKNAKCINTDGSYKCLCLPGYVPSDKPNYCTPLNTALNLEKDSDL 1721
Query: 1396 E 1396
E
Sbjct: 1722 E 1722
Score = 38.1 bits (87), Expect = 0.060
Identities = 32/110 (29%), Positives = 42/110 (38%), Gaps = 14/110 (12%)
Query: 77 CHLPCMNGGQCSSRDKCQCPPNFTGKLCQI--------PVHGASVPKLYQHSQQPGKALG 128
C PC NGG C C C P GK C+ PV G P P +A
Sbjct: 191 CVPPCQNGGMCLRPQLCVCKPGTKGKACETIAAQDTSSPVFGGQSPGAASSWGPPEQAAK 250
Query: 129 THVIHSTHTLP-LTVTSQQGVKVKFPPNI---VNIHVKHPP--EASVQIH 172
TLP ++ +Q + +K P++ IH + P SV IH
Sbjct: 251 HTSSKKADTLPRVSPVAQMTLTLKPKPSVGLPQQIHSQVTPLSSQSVVIH 300
>gi|4557733 latent transforming growth factor beta binding protein 2
[Homo sapiens]
Length = 1821
Score = 1078 bits (2788), Expect = 0.0
Identities = 610/1538 (39%), Positives = 799/1538 (51%), Gaps = 250/1538 (16%)
Query: 25 RIKVVFTPSICKVTCTKGSCQNSCEKGNTTTLISENGHAADTLTATNFRVVICHLPCMNG 84
+IK+VFTP+ICK TC +G C NSCE+G+TTTL S+ GH D + FR+ C +PC+NG
Sbjct: 350 KIKIVFTPTICKQTCARGHCANSCERGDTTTLYSQGGHGHDP--KSGFRIYFCQIPCLNG 407
Query: 85 GQCSSRDKCQCPPNFTGKLCQIPVHGASVPKLYQHSQQPGKALGTHVIHSTHTLPLTVTS 144
G+C RD+C CP N TGK C +P+ + S+ P L + ST TLPL S
Sbjct: 408 GRCIGRDECWCPANSTGKFCHLPIPQPDREPPGRGSR-PRALLEAPLKQSTFTLPL---S 463
Query: 145 QQGVKVKFPPNIVNIHVKHPPEASVQIHQVSRIDGPTGQKTKE------------AQPGQ 192
Q V P++V +H+ HPPEASVQIHQV+++ G + E A PG
Sbjct: 464 NQLASVN--PSLVKVHIHHPPEASVQIHQVAQVRGGVEEALVENSVETRPPPWLPASPGH 521
Query: 193 SQVSYQGLPVQKTQTIHSTYSHQQVIPHVYPVAA---KTQLGRCFQETIGSQCGKALPGL 249
S +P + + P P AA + LGRC+ T+ QC L L
Sbjct: 522 SLWDSNNIPARSGEP-----------PRPLPPAAPRPRGLLGRCYLNTVNGQCANPLLEL 570
Query: 250 SKQEDCCGTVGTSWGFNKCQKCPKKPSYHGY-NQMMECLPGYKRVNNTFCQDINECQLQG 308
+ QEDCCG+VG WG C CP +P+ N +EC GYKR+N T CQDINEC G
Sbjct: 571 TTQEDCCGSVGAFWGVTLCAPCPPRPASPVIENGQLECPQGYKRLNLTHCQDINECLTLG 630
Query: 309 VCPNGECLNTMGSYRCTCKIGFGPDPTFSSCVPDPPVISEEKGPCYRLVSSGRQCMHPLS 368
+C + EC+NT GSY CTC+ G DP+ S CV D IS +G CYR + G C PL+
Sbjct: 631 LCKDAECVNTRGSYLCTCRPGLMLDPSRSRCVSD-KAISMLQGLCYRSLGPG-TCTLPLA 688
Query: 369 VHLTKQLCCCS-VGKAWGPHCEKCPLPGTAAFKEICPGGMGYTVSGVHRRRPIHHHVGKG 427
+TKQ+CCCS VGKAWG CEKCPLPGT AF+EICP G GYT + R + +
Sbjct: 689 QRITKQICCCSRVGKAWGSECEKCPLPGTEAFREICPAGHGYTYASSDIR--LSMRKAEE 746
Query: 428 PVFVKPKNTQPVAKSTHPPPLPAKEEPVEALTFSREHGPGVAEPEVATAPPEKEIPSLDQ 487
+P Q +S+ P PA+ +P+ +T + E T P
Sbjct: 747 EELARPPREQG-QRSSGALPGPAERQPLRVVTDT--------WLEAGTIP---------- 787
Query: 488 EKTKLEPGQPQLSPGISTIHLHPQFPGIVIEKTSPPVP---VEVAPEASTSSASQVIAPT 544
+ G Q +++ P + + T+PP+P + E + ++ V+
Sbjct: 788 -----DKGDSQAGQVTTSVTHAPAW--VTGNATTPPMPEQGIAEIQEEQVTPSTDVLVTL 840
Query: 545 QVTEINECTVN-PDICGAGHCINLPVRYTCICYEGYRFSEQQRKCVDIDECTQVQHLCSQ 603
I+ C ++CG G C+NLP Y C+C GY+ Q C D +EC + +
Sbjct: 841 STPGIDRCAAGATNVCGPGTCVNLPDGYRCVCSPGYQLHPSQAYCTDDNECLR-DPCKGK 899
Query: 604 GRCENTEGSFLCICPAGFMASEEGT--NCIDVDECLRPDVCGEGHCVNTVGAFRCEYCDS 661
GRC N GS+ C C G+ + G C D++EC +P VC G C NT G++ CE CD
Sbjct: 900 GRCINRVGSYSCFCYPGYTLATSGATQECQDINECEQPGVCSGGQCTNTEGSYHCE-CDQ 958
Query: 662 GYRMTQRGRCEDIDECLNPSTCPDEQCVNSPGSYQCVPCTEGFRGWNGQCLDVDECLEPN 721
GY M ++G C+DI+EC +P TCPD +CVNSPGSY C+ C EG+RG +G C+DV+ECL P
Sbjct: 959 GYIMVRKGHCQDINECRHPGTCPDGRCVNSPGSYTCLACEEGYRGQSGSCVDVNECLTPG 1018
Query: 722 VCANGDCSNLEGSYMCSCHKGYTRTPDHKHCRDIDECQQGNLCVNGQCKNTEGSFRCT-C 780
VCA+G C+NLEGS+ CSC +GY T D K C+D+DEC C G C NTEGSF C+ C
Sbjct: 1019 VCAHGKCTNLEGSFRCSCEQGYEVTSDEKGCQDVDECASRASCPTGLCLNTEGSFACSAC 1078
Query: 781 GQGYQLSAAKDQCEDIDECQHRHLCAHGQCRNTEGSFQCV-CDQGYRASGLGDHCEDINE 839
GY ++ CED+DEC +C G C NT GSF C CD GYR S LGD CED++E
Sbjct: 1079 ENGYWVNEDGTACEDLDECAFPGVCPSGVCTNTAGSFSCKDCDGGYRPSPLGDSCEDVDE 1138
Query: 840 CLEDKSVCQRGDCINTAGSYDCTCPDGFQLDDNKTCQDINECEHPGLCGPQGECLNTEGS 899
C + +S C G+C NT GSY C CP GFQL + C+D+NEC C P GECLN+ GS
Sbjct: 1139 CEDPQSSCLGGECKNTVGSYQCLCPQGFQLANGTVCEDVNECMGEEHCAPHGECLNSHGS 1198
Query: 900 FHCVCQQGFSISADGRTCEDIDECVNNTVCDSHGFCDNTAGSFRCLCYQGFQAPQDGQGC 959
F C+C GF + G +C+D+DEC C G C NT GSF CLC GFQ + C
Sbjct: 1199 FFCLCAPGFVSAEGGTSCQDVDECATTDPCVG-GHCVNTEGSFNCLCETGFQPSPESGEC 1257
Query: 960 VDVNECELLSG-VCG-------------------------------------------EA 975
VD++ECE VCG
Sbjct: 1258 VDIDECEDYGDPVCGTWKCENSPGSYRCVLGCQPGFHMAPNGDCIDIDECANDTMCGSHG 1317
Query: 976 FCENVEGSFLCVCADENQEYSPMTGQCRSRTSTDLDVDVDQPKEEKKECYYNLNDASLCD 1035
FC+N +GSF C+C D+ E SP C VDV++ + C A+LC+
Sbjct: 1318 FCDNTDGSFRCLC-DQGFEISPSGWDC---------VDVNECELMLAVC-----GAALCE 1362
Query: 1036 NV-----------LAPNVTKQECCCTSGAG--------WGDNCEI-------------FP 1063
NV L ++ C GAG GD+ P
Sbjct: 1363 NVEGSFLCLCASDLEEYDAQEGHCRPRGAGGQSMSEAPTGDHAPAPTRMDCYSGQKGHAP 1422
Query: 1064 C-PVLG--TAEFTEMCPKGKGFVPA-----GESSSE-----AGGENYKDADECLLFGQE- 1109
C VLG T + C +G + A E S+E G+ Y + FGQ
Sbjct: 1423 CSSVLGRNTTQAECCCTQGASWGDACDLCPSEDSAEFSEICPSGKGYIPVEGAWTFGQTM 1482
Query: 1110 -------------ICKNGFCLNTRPGYECYCKQGTYYDPVKLQCFDMDECQDPSSCIDGQ 1156
+C NG CLNT PGY C C G +YD +C D DECQD +C +G+
Sbjct: 1483 YTDADECVIFGPGLCPNGRCLNTVPGYVCLCNPGFHYDASHKKCEDHDECQD-LACENGE 1541
Query: 1157 CVNTEGSYNCFCTHPMVLDASEKRCIRPAESNEQIEETDVYQDLCWEHLSDEYVCSRPLV 1216
CVNTEGS++CFC+ P+ LD S++RC+ S E + + D++ D+CW+ ++++ VCS PL
Sbjct: 1542 CVNTEGSFHCFCSPPLTLDLSQQRCMNSTSSTEDLPDHDIHMDICWKKVTND-VCSEPLR 1600
Query: 1217 GKQTTYTECCCLYGEAWGMQCALCPLKDSDDYAQLCNIP-VTGRRQP------------- 1262
G +TTYTECCC GEAW QCALCP + S+ YAQLCN+ + R+
Sbjct: 1601 GHRTTYTECCCQDGEAWSQQCALCPPRSSEVYAQLCNVARIEAEREAGVHFRPGYEYGPG 1660
Query: 1263 --------YGRDALVDFS----EQYTPE--------------------ADPYFIQDRFLN 1290
YG D ++ E PE P +Q ++
Sbjct: 1661 PDDLHYSIYGPDGAPFYNYLGPEDTVPEPAFPNTAGHSADRTPILESPLQPSELQPHYVA 1720
Query: 1291 S-------FEELQAEECGILNGCENGRCVRVQEGYTCDCFDGYHLDTAKMTCVDVNECDE 1343
S FE LQAEECGILNGCENGRCVRV+EGYTCDCF+G+ LD A M CVDVNECD+
Sbjct: 1721 SHPEPPAGFEGLQAEECGILNGCENGRCVRVREGYTCDCFEGFQLDAAHMACVDVNECDD 1780
Query: 1344 LNNRMSLCKNAKCINTDGSYKCLCLPGYVPSDKPNYCT 1381
LN LC + C NT+GSY+C C PGYV P +CT
Sbjct: 1781 LNGPAVLCVHGYCENTEGSYRCHCSPGYVAEAGPPHCT 1818
Score = 176 bits (445), Expect = 2e-43
Identities = 153/593 (25%), Positives = 222/593 (37%), Gaps = 152/593 (25%)
Query: 845 SVCQRGDCINTAGSYDCTCPDGFQLDDNKT-CQDINECEHPGLCGPQGECLNTEGSFHCV 903
+VC G C+N Y C C G+QL ++ C D NEC C +G C+N GS+ C
Sbjct: 854 NVCGPGTCVNLPDGYRCVCSPGYQLHPSQAYCTDDNECLRDP-CKGKGRCINRVGSYSCF 912
Query: 904 CQQGFSISADGRT--CEDIDECVNNTVCDSHGFCDNTAGSFRCLCYQGFQAPQDGQGCVD 961
C G++++ G T C+DI+EC VC S G C NT GS+ C C QG+ + G C D
Sbjct: 913 CYPGYTLATSGATQECQDINECEQPGVC-SGGQCTNTEGSYHCECDQGYIMVRKGH-CQD 970
Query: 962 VNECELLSGVCGEAFCENVEGSFLCVCADENQEYSPMTGQCRSRTSTDLDVDVDQPKEEK 1021
+NEC G C + C N GS+ C+ +E Y +G C VDV+
Sbjct: 971 INECRH-PGTCPDGRCVNSPGSYTCLACEEG--YRGQSGSC---------VDVN------ 1012
Query: 1022 KECYYNLNDASLCDNVLAPNVTKQECCCTSGAGWGDNCEIFPCPVLGTAEFTEMCPKGKG 1081
EC L P V C + +CE +G
Sbjct: 1013 -EC-------------LTPGVCAHGKCTNLEGSFRCSCE-------------------QG 1039
Query: 1082 FVPAGESSSEAGGENYKDADECLLFGQEICKNGFCLNTRPGYECY-CKQGTYYDPVKLQC 1140
+ E +S+ G +D DEC + C G CLNT + C C+ G + + C
Sbjct: 1040 Y----EVTSDEKG--CQDVDECA--SRASCPTGLCLNTEGSFACSACENGYWVNEDGTAC 1091
Query: 1141 FDMDECQDPSSCIDGQCVNTEGSYNCFCTHPMVLDASEKRC---IRPAESNEQIEETDVY 1197
D+DEC P C G C NT GS++C K C RP+ + E+ D
Sbjct: 1092 EDLDECAFPGVCPSGVCTNTAGSFSC------------KDCDGGYRPSPLGDSCEDVDEC 1139
Query: 1198 QDLCWEHLSDEYVCSRPLVGKQTTYTECCCLYGEAW---GMQCALCPLKDSDDYAQLCNI 1254
+D + CL GE G LCP +C
Sbjct: 1140 ED-----------------------PQSSCLGGECKNTVGSYQCLCPQGFQLANGTVCED 1176
Query: 1255 --PVTGRRQPYGRDALVDFSEQYTPEADPYFIQDRFLNSFEELQAEECGILNGCENGRCV 1312
G ++ + P F+ S +++ +EC + C G CV
Sbjct: 1177 VNECMGEEHCAPHGECLNSHGSFFCLCAPGFVSAEGGTSCQDV--DECATTDPCVGGHCV 1234
Query: 1313 RVQEGYTCDCFDGYHLDTAKMTCVDVNECDELNNRMS---LCKNAK-------------- 1355
+ + C C G+ CVD++EC++ + + C+N+
Sbjct: 1235 NTEGSFNCLCETGFQPSPESGECVDIDECEDYGDPVCGTWKCENSPGSYRCVLGCQPGFH 1294
Query: 1356 ------------------------CINTDGSYKCLCLPGYVPSDKPNYCTPLN 1384
C NTDGS++CLC G+ S C +N
Sbjct: 1295 MAPNGDCIDIDECANDTMCGSHGFCDNTDGSFRCLCDQGFEISPSGWDCVDVN 1347
Score = 130 bits (327), Expect = 9e-30
Identities = 186/772 (24%), Positives = 267/772 (34%), Gaps = 164/772 (21%)
Query: 659 CDSGYRMTQRGRCEDIDECLNPSTCPDEQCVNSPGSYQCVPCTEGFRGWNGQCLDVDE-- 716
C GY+ C+DI+ECL C D +CVN+ GSY C C G LD
Sbjct: 608 CPQGYKRLNLTHCQDINECLTLGLCKDAECVNTRGSYLCT-CRPGLM------LDPSRSR 660
Query: 717 CLEPNVCA--NGDCSNLEGSYMCSCHKGYTRTPDHKHCRDIDECQQGNLCVNGQCKNTEG 774
C+ + G C G C+ T C + + G+ C TE
Sbjct: 661 CVSDKAISMLQGLCYRSLGPGTCTLPLAQRITKQICCCSRVGKAW-GSECEKCPLPGTE- 718
Query: 775 SFR--CTCGQGYQLSAAKDQCEDIDECQHRHLCAHGQCRNTEGSFQCVCDQGYRASG-LG 831
+FR C G GY A+ D + + + L + +QG R+SG L
Sbjct: 719 AFREICPAGHGYTY-ASSDIRLSMRKAEEEELARPPR------------EQGQRSSGALP 765
Query: 832 DHCED------INECLEDKSVCQRGDC----INTAGSYDCTCPDGFQLDDNKTCQDINEC 881
E + LE ++ +GD + T+ ++ G Q I E
Sbjct: 766 GPAERQPLRVVTDTWLEAGTIPDKGDSQAGQVTTSVTHAPAWVTGNATTPPMPEQGIAEI 825
Query: 882 EHPGLCGPQGECLNTEGSFHCVCQQGFSISADGRTCEDIDECVNNT--VCDSHGFCDNTA 939
+ + P + L T +S G ID C VC G C N
Sbjct: 826 QEEQVT-PSTDVLVT-------------LSTPG-----IDRCAAGATNVCGP-GTCVNLP 865
Query: 940 GSFRCLCYQGFQAPQDGQGCVDVNECELLSGVC-GEAFCENVEGSFLCVCADENQEYSPM 998
+RC+C G+Q C D NEC L C G+ C N GS+ C C Y
Sbjct: 866 DGYRCVCSPGYQLHPSQAYCTDDNEC--LRDPCKGKGRCINRVGSYSCFC------YPGY 917
Query: 999 TGQCRSRTSTDLDVDVDQPKEEKKECYYNLNDASLCDNVLAPNVT-KQECCCTSG---AG 1054
T T D++ EC +C N C C G
Sbjct: 918 TLATSGATQECQDIN---------EC----EQPGVCSGGQCTNTEGSYHCECDQGYIMVR 964
Query: 1055 WGDNCEIFPCPVLGTAEFTEMCPKGKGFVPAGESSSEAGGENYK-------DADECLLFG 1107
G +I C GT CP G+ G + A E Y+ D +ECL G
Sbjct: 965 KGHCQDINECRHPGT------CPDGRCVNSPGSYTCLACEEGYRGQSGSCVDVNECLTPG 1018
Query: 1108 QEICKNGFCLNTRPGYECYCKQGTYYDPVKLQCFDMDECQDPSSCIDGQCVNTEGSYNCF 1167
+C +G C N + C C+QG + C D+DEC +SC G C+NTEGS+ C
Sbjct: 1019 --VCAHGKCTNLEGSFRCSCEQGYEVTSDEKGCQDVDECASRASCPTGLCLNTEGSFACS 1076
Query: 1168 -CTHPMVLDASEKRCIRPAESNEQIEETDVYQDLCWEHLSDEYVCSRPLVGKQTTYTECC 1226
C + ++ C E ++E C+ P V T
Sbjct: 1077 ACENGYWVNEDGTAC-------EDLDE-----------------CAFPGVCPSGVCTNT- 1111
Query: 1227 CLYGEAWGMQCALC-------PLKDSDDYAQLCNIPVTGRRQPYGRDALVDFSEQYTPEA 1279
A C C PL DS + C P + ++ + +
Sbjct: 1112 -----AGSFSCKDCDGGYRPSPLGDSCEDVDECEDPQSSCLGGECKNTVGSY-------- 1158
Query: 1280 DPYFIQDRFLNSFEELQAEECGILNGC-------ENGRCVRVQEGYTCDCFDGYHLDTAK 1332
Q F+ C +N C +G C+ + C C G+
Sbjct: 1159 -----QCLCPQGFQLANGTVCEDVNECMGEEHCAPHGECLNSHGSFFCLCAPGFVSAEGG 1213
Query: 1333 MTCVDVNECDELNNRMSLCKNAKCINTDGSYKCLCLPGYVPSDKPNYCTPLN 1384
+C DV+EC + C C+NT+GS+ CLC G+ PS + C ++
Sbjct: 1214 TSCQDVDECATTDP----CVGGHCVNTEGSFNCLCETGFQPSPESGECVDID 1261
Score = 36.2 bits (82), Expect = 0.23
Identities = 14/39 (35%), Positives = 19/39 (48%)
Query: 1349 SLCKNAKCINTDGSYKCLCLPGYVPSDKPNYCTPLNTAL 1387
++C C+N Y+C+C PGY YCT N L
Sbjct: 854 NVCGPGTCVNLPDGYRCVCSPGYQLHPSQAYCTDDNECL 892
Score = 33.9 bits (76), Expect = 1.1
Identities = 15/41 (36%), Positives = 19/41 (46%), Gaps = 1/41 (2%)
Query: 66 TLTATNFRVV-ICHLPCMNGGQCSSRDKCQCPPNFTGKLCQ 105
T +TN + +C PC N G CS C C F G C+
Sbjct: 179 TANSTNHCIKPVCEPPCQNRGSCSRPQLCVCRSGFRGARCE 219
>gi|110347437 latent transforming growth factor beta binding protein 4
isoform c [Homo sapiens]
Length = 1557
Score = 922 bits (2383), Expect = 0.0
Identities = 526/1355 (38%), Positives = 703/1355 (51%), Gaps = 173/1355 (12%)
Query: 25 RIKVVFTPSICKVTCTKGS----CQNSCEKGNTTTLIS-ENGHAADTLTATNFRVVICHL 79
R++V FTP +C + C G C +C N T++ S G AA FR +C L
Sbjct: 31 RLRVRFTPVVCGLRCVHGPTGSRCTPTCAPRNATSVDSGAPGGAAPG--GPGFRAFLCPL 88
Query: 80 PCMNGGQCSSRDKCQCPPNFTGKLCQIPVHGASVPKLYQHSQQPGKALGTHVIHSTHTLP 139
C NGG C D+C CPP+F GK CQ+ GA P PG + S +T+P
Sbjct: 89 ICHNGGVCVKPDRCLCPPDFAGKFCQLHSSGARPPA----PAVPG------LTRSVYTMP 138
Query: 140 LTV--TSQQGVKVKFPPNIVNIHVKHPPEASVQIHQVSRIDGPTGQKTKEAQPGQSQVSY 197
L + GV ++V++HV+HP EASV +HQV R+ GP + EA +
Sbjct: 139 LANHRDDEHGVA-----SMVSVHVEHPQEASVVVHQVERVSGPWEEADAEAVARAEAAAR 193
Query: 198 QGLPVQKTQTIHSTYSHQQVIPHVYPVAAKTQLGRCFQETIGSQCGKALPGLSKQEDCCG 257
T S P + + G CF+E G +C LPGL QE CC
Sbjct: 194 AEAAAPYTVLAQSA-------PREDGYSDASGFGYCFRELRGGECASPLPGLRTQEVCCR 246
Query: 258 TVGTSWGFNKCQKCPKKPSYHGYNQMME-----CLPGYKRVNNTFCQDINECQLQGVCPN 312
G +WG + CQ C ++ G ++ + C G++RVN + C+D++EC G C +
Sbjct: 247 GAGLAWGVHDCQLCSERL---GNSERVSAPDGPCPTGFERVNGS-CEDVDECATGGRCQH 302
Query: 313 GECLNTMGSYRCTCKIGFGPDPTFSSCVPDPPVISEEKGPCYRLVSSGRQCMHPLSVHLT 372
GEC NT G Y C C GF D + SSC+ VISE KGPC+R++ G C P+ ++T
Sbjct: 303 GECANTRGGYTCVCPDGFLLDSSRSSCISQH-VISEAKGPCFRVLRDGG-CSLPILRNIT 360
Query: 373 KQLCCCS-VGKAWGPHCEKCPLPGTAAFKEICPGGMGYTVSGVHRR---RPIHHH---VG 425
KQ+CCCS VGKAWG C+ CP G+ F+EICP G GY S R RP+ V
Sbjct: 361 KQICCCSRVGKAWGRGCQLCPPFGSEGFREICPAGPGYHYSASDLRYNTRPLGQEPPRVS 420
Query: 426 KGPVFVKPKNTQPVAK--STH---------PPPLPAKEEPVEALTFSR-----EHGP--G 467
P ++P A TH P P P E P+ ++ E GP G
Sbjct: 421 LSQPRTLPATSRPSAGFLPTHRLEPRPEPRPDPRPGPELPLPSIPAWTGPEIPESGPSSG 480
Query: 468 VAEPEVATAPPEKEI--PS-------------------LDQEKTK-----LEPGQPQLSP 501
+ + P + I PS +D ++ + PG+ + SP
Sbjct: 481 MCQRNPQVCGPGRCISRPSGYTCACDSGFRLSPQGTRCIDVDECRRVPPPCAPGRCENSP 540
Query: 502 GISTIHLHPQFPG--------IVIEKTSPPVPVEVAPEASTSSASQVIAPT--------- 544
G P F V E P P ++ +T + + P
Sbjct: 541 GSFRCVCGPGFRAGPRAAECLDVDECHRVPPPCDLGRCENTPGSFLCVCPAGYQAAPHGA 600
Query: 545 QVTEINECTVNPDICGAGHCINLPVRYTCICYEGYRFSEQQRKCVDIDECTQVQHLCSQG 604
+++ECT +P +CG G C NLP + C+C G+R S + D+DEC Q C G
Sbjct: 601 SCQDVDECTQSPGLCGRGACKNLPGSFRCVCPAGFRGSACEE---DVDECAQEPPPCGPG 657
Query: 605 RCENTEGSFLCICPAGFMASEEGTNCIDVDECLR-PDVCGEGHCVNTVGAFRCEYCDSGY 663
RC+NT GSF C CPAGF + G C DVDEC R P C G C NT G+F+C C G+
Sbjct: 658 RCDNTAGSFHCACPAGFRSRGPGAPCQDVDECARSPPPCTYGRCENTEGSFQC-VCPMGF 716
Query: 664 RMTQRG-RCEDIDECLNPSTCPDEQCVNSPGSYQCVPCTEGFRGWNGQCLDVDECLE--P 720
+ G CED+DEC N CP ++CVNSPGS+QC C G G+C DVDEC P
Sbjct: 717 QPNTAGSECEDVDECENHLACPGQECVNSPGSFQCRTCPSGHHLHRGRCTDVDECSSGAP 776
Query: 721 NVCANGDCSNLEGSYMCSCHKGYTRTPDHKH--CRDIDECQQGNLCV-NGQCKNTEGSFR 777
+G C+N EGS+ CSC GY R P + C D++EC +G+ C +G+C NT+GSF
Sbjct: 777 PCGPHGHCTNTEGSFRCSCAPGY-RAPSGRPGPCADVNECLEGDFCFPHGECLNTDGSFA 835
Query: 778 CTCGQGYQLSAAKDQCEDIDECQHRHLCAHGQCRNTEGSFQCVCDQGYRASGLGDHCEDI 837
CTC GY+ C D+DEC LC G C NT+GSF+C+C G+RA C D+
Sbjct: 836 CTCAPGYRPGPRGASCLDVDECSEEDLCQSGICTNTDGSFECICPPGHRAGPDLASCLDV 895
Query: 838 NECLE-DKSVCQRGDCINTAGSYDCT--CPDGFQLDDNKTCQDINECEH--PGLCGPQGE 892
+EC E ++C C N+ GSY C C G+ TC D++EC+ P +CG Q
Sbjct: 896 DECRERGPALCGSQRCENSPGSYRCVRDCDPGYHAGPEGTCDDVDECQEYGPEICGAQ-R 954
Query: 893 CLNTEGSFHCV--CQQGFSISADGRTCEDIDECVNNTVCDSHGFCDNTAGSFRCLCYQGF 950
C NT GS+ C C G+ + G C+D+DEC N + C +H C N GSF+CLC QG+
Sbjct: 955 CENTPGSYRCTPACDPGYQPTPGGG-CQDVDECRNRSFCGAHAVCQNLPGSFQCLCDQGY 1013
Query: 951 QAPQDGQGCVDVNECELLSGVCGEAFCENVEGSFLCVCADENQEYSPMTGQCRSRTSTDL 1010
+ +DG+ CVDVNECE L GVCG A CENVEGSFLCVC + +E+ PMTG+C ++
Sbjct: 1014 EGARDGRHCVDVNECETLQGVCGAALCENVEGSFLCVCPNSPEEFDPMTGRCVPPRTSAG 1073
Query: 1011 DVDVDQPKEE-----------------------------KKECYYNLNDASLCDNVLAPN 1041
QP+ ++ECY++ CDN+LA N
Sbjct: 1074 TFPGSQPQAPASPVLPARPPPPPLPRRPSTPRQGPVGSGRRECYFDTAAPDACDNILARN 1133
Query: 1042 VTKQECCCTSGAGWGDNCEIFPCPVLGTAEFTEMCPKGKGFV-PAGESSSEAGGENYKDA 1100
VT QECCCT G GWG C I CP TAE+ +CP G+G++ P+G+ S +D
Sbjct: 1134 VTWQECCCTVGEGWGSGCRIQQCPGTETAEYQSLCPHGRGYLAPSGDLSLR------RDV 1187
Query: 1101 DECLLFGQEICKNGFCLNTRPGYECYCKQGTYYDPVKLQCFDMDECQDPS-SCIDGQCVN 1159
DEC LF ++CK+G C+NT PGY CYC G YY +L+C D DEC D +C G+CVN
Sbjct: 1188 DECQLFRDQVCKSGVCVNTAPGYSCYCSNGYYYHTQRLECIDNDECADEEPACEGGRCVN 1247
Query: 1160 TEGSYNCFCTHPMVLDASEKRCIRPAESNEQIEETDVYQDLCWEHLSDEYVCSRPLVGKQ 1219
T GSY+C C P+VLD S++RC+ SNE + D +CW+ + + VCS P + +Q
Sbjct: 1248 TVGSYHCTCEPPLVLDGSQRRCV----SNES-QSLDDNLGVCWQEVGADLVCSHPRLDRQ 1302
Query: 1220 TTYTECCCLYGEAWGMQCALCPLKDSDDYAQLCNI 1254
TYTECCCLYGEAWGM CALCP +DSDD+ LCN+
Sbjct: 1303 ATYTECCCLYGEAWGMDCALCPAQDSDDFEALCNV 1337
Score = 257 bits (657), Expect = 5e-68
Identities = 205/647 (31%), Positives = 265/647 (40%), Gaps = 110/647 (17%)
Query: 758 CQQG-NLCVNGQCKNTEGSFRCTCGQGYQLSAAKDQCEDIDECQH-RHLCAHGQCRNTEG 815
CQ+ +C G+C + + C C G++LS +C D+DEC+ CA G+C N+ G
Sbjct: 482 CQRNPQVCGPGRCISRPSGYTCACDSGFRLSPQGTRCIDVDECRRVPPPCAPGRCENSPG 541
Query: 816 SFQCVCDQGYRASGLGDHCEDINECLEDKSVCQRGDCINTAGSYDCTCPDGFQLDDN-KT 874
SF+CVC G+RA C D++EC C G C NT GS+ C CP G+Q + +
Sbjct: 542 SFRCVCGPGFRAGPRAAECLDVDECHRVPPPCDLGRCENTPGSFLCVCPAGYQAAPHGAS 601
Query: 875 CQDINEC-EHPGLCGPQGECLNTEGSFHCVCQQGFSISADGRTCE-DIDECVNNTVCDSH 932
CQD++EC + PGLCG +G C N GSF CVC GF G CE D+DEC
Sbjct: 602 CQDVDECTQSPGLCG-RGACKNLPGSFRCVCPAGFR----GSACEEDVDECAQEPPPCGP 656
Query: 933 GFCDNTAGSFRCLCYQGFQAPQDGQGCVDVNECELLSGVCGEAFCENVEGSFLCVCADEN 992
G CDNTAGSF C C GF++ G C DV+EC C CEN EGSF CVC
Sbjct: 657 GRCDNTAGSFHCACPAGFRSRGPGAPCQDVDECARSPPPCTYGRCENTEGSFQCVC---- 712
Query: 993 QEYSPMTGQCRSRTSTDLDVDVDQPKEEKKECYYNLNDASLCDNVLAPNVTKQECCCTSG 1052
PM Q P EC D C+N LA QEC + G
Sbjct: 713 ----PMGFQ---------------PNTAGSEC----EDVDECENHLA--CPGQECVNSPG 747
Query: 1053 AGWGDNCEIFPCPVLGTAEFTEMCPKGKGFVPAGESSSEAGGENYKDADECLLFGQEICK 1112
+ F C CP G + G + D DEC
Sbjct: 748 S--------FQC---------RTCPSGH-HLHRGRCT---------DVDECSSGAPPCGP 780
Query: 1113 NGFCLNTRPGYECYCKQGTYYDPVKLQ--CFDMDECQDPSSCID-GQCVNTEGSYNCFCT 1169
+G C NT + C C G Y P C D++EC + C G+C+NT+GS+ C C
Sbjct: 781 HGHCTNTEGSFRCSCAPG-YRAPSGRPGPCADVNECLEGDFCFPHGECLNTDGSFACTCA 839
Query: 1170 HPMVLDASEKRCIRPAESNEQIEETDVYQDLCWEHLSDEYVCSRPLVGKQTTYTECCCLY 1229
RP + D S+E +C + EC C
Sbjct: 840 PGY----------RPGPRGASCLDVD--------ECSEEDLCQSGICTNTDGSFECICPP 881
Query: 1230 GEAWGMQCALCPLKDSDDYAQ----LCNIPVTGRRQPYGRDALVDFSEQYTPEADPYFIQ 1285
G G A C D D+ + LC P + D Y A P
Sbjct: 882 GHRAGPDLASC--LDVDECRERGPALCGSQRC-ENSPGSYRCVRDCDPGY--HAGPEGTC 936
Query: 1286 DRFLNSFEELQAEECGILNGCENGRCVRVQEGYTCD--CFDGYHLDTAKMTCVDVNECDE 1343
D ++ +E E CG RC Y C C GY T C DV+EC
Sbjct: 937 DD-VDECQEYGPEICGAQ------RCENTPGSYRCTPACDPGYQ-PTPGGGCQDVDEC-- 986
Query: 1344 LNNRMSLCKNAKCINTDGSYKCLCLPGYVPSDKPNYCTPLNTALNLE 1390
NR +A C N GS++CLC GY + +C +N L+
Sbjct: 987 -RNRSFCGAHAVCQNLPGSFQCLCDQGYEGARDGRHCVDVNECETLQ 1032
Score = 153 bits (386), Expect = 1e-36
Identities = 127/463 (27%), Positives = 176/463 (38%), Gaps = 93/463 (20%)
Query: 233 CFQETIGSQ-CGKALPGLSKQEDCCGTVGTSWGFN-KCQKCPKK---------PSYHGY- 280
C+ +T C L ++CC TVG WG + Q+CP P GY
Sbjct: 1116 CYFDTAAPDACDNILARNVTWQECCCTVGEGWGSGCRIQQCPGTETAEYQSLCPHGRGYL 1175
Query: 281 ---------NQMMEC----------------LPGYK---------RVNNTFCQDINEC-Q 305
+ EC PGY C D +EC
Sbjct: 1176 APSGDLSLRRDVDECQLFRDQVCKSGVCVNTAPGYSCYCSNGYYYHTQRLECIDNDECAD 1235
Query: 306 LQGVCPNGECLNTMGSYRCTCKIGFGPDPTFSSCVP-DPPVISEEKGPCYRLVSSGRQCM 364
+ C G C+NT+GSY CTC+ D + CV + + + G C++ V + C
Sbjct: 1236 EEPACEGGRCVNTVGSYHCTCEPPLVLDGSQRRCVSNESQSLDDNLGVCWQEVGADLVCS 1295
Query: 365 HP-LSVHLTKQLCCCSVGKAWGPHCEKCPLPGTAAFKEIC------------PGGMGYTV 411
HP L T CCC G+AWG C CP + F+ +C PGG G
Sbjct: 1296 HPRLDRQATYTECCCLYGEAWGMDCALCPAQDSDDFEALCNVLRPPAYSPPRPGGFGL-- 1353
Query: 412 SGVHRRRPIHHHVGKGPVFVKPKNTQPVAKSTHPPP-LPAKEEPVEALTFSREHGPGVAE 470
P + GP P P +PPP LP P F+R P A
Sbjct: 1354 -------PYEYGPDLGP----PYQGLPYGPELYPPPALPYDPYPPPPGPFARREAPYGA- 1401
Query: 471 PEVATAPPEKEIPSLDQEKTKLEPGQPQLSPGISTIHLHPQFPGIVIEKTSPPVPVEVAP 530
P ++P + + + PG T + + S P P E P
Sbjct: 1402 -------PRFDMPDFEDDGGPYGESEAPAPPGPGTRWPYRSRD----TRRSFPEPEE--P 1448
Query: 531 EASTSSASQVIAPTQVTEINECTVNPDICGAGHCINLPVRYTCICYEGYRFSEQQRKCVD 590
S A + P + E EC + D C G C+ +P +TC C++GYR + CVD
Sbjct: 1449 PEGGSYAGSLAEPYEELEAEECGIL-DGCTNGRCVRVPEGFTCRCFDGYRLDMTRMACVD 1507
Query: 591 IDECTQVQ---HLCSQGRCENTEGSFLCICPAGFMASEEGTNC 630
I+EC + + LC RC NT+GSF CIC GF + + +C
Sbjct: 1508 INECDEAEAASPLCVNARCLNTDGSFRCICRPGFAPTHQPHHC 1550
Score = 151 bits (381), Expect = 5e-36
Identities = 69/130 (53%), Positives = 86/130 (66%), Gaps = 4/130 (3%)
Query: 1255 PVTGRRQPY-GRDALVDFSE-QYTPEADPYFIQDRFLNSFEELQAEECGILNGCENGRCV 1312
P G R PY RD F E + PE Y +EEL+AEECGIL+GC NGRCV
Sbjct: 1425 PGPGTRWPYRSRDTRRSFPEPEEPPEGGSY--AGSLAEPYEELEAEECGILDGCTNGRCV 1482
Query: 1313 RVQEGYTCDCFDGYHLDTAKMTCVDVNECDELNNRMSLCKNAKCINTDGSYKCLCLPGYV 1372
RV EG+TC CFDGY LD +M CVD+NECDE LC NA+C+NTDGS++C+C PG+
Sbjct: 1483 RVPEGFTCRCFDGYRLDMTRMACVDINECDEAEAASPLCVNARCLNTDGSFRCICRPGFA 1542
Query: 1373 PSDKPNYCTP 1382
P+ +P++C P
Sbjct: 1543 PTHQPHHCAP 1552
Score = 110 bits (276), Expect = 7e-24
Identities = 84/308 (27%), Positives = 122/308 (39%), Gaps = 54/308 (17%)
Query: 1131 TYYDPVKLQCFDMDECQDPSSCIDGQCVNTEGSYNCFCTHPMVLDASEKRCIRPAESNEQ 1190
T ++ V C D+DEC C G+C NT G Y C C +LD+S CI S
Sbjct: 279 TGFERVNGSCEDVDECATGGRCQHGECANTRGGYTCVCPDGFLLDSSRSSCI----SQHV 334
Query: 1191 IEETDVYQDLCWEHLSDEYVCSRPLVGKQTTYTECCCLYGEAWGMQCALCPLKDSDDYAQ 1250
I E + C+ L D CS P++ T CC G+AWG C LCP S+ + +
Sbjct: 335 ISEA---KGPCFRVLRDGG-CSLPILRNITKQICCCSRVGKAWGRGCQLCPPFGSEGFRE 390
Query: 1251 LCNI---------PVTGRRQPYGRDA-LVDFSEQYT----------------------PE 1278
+C + +P G++ V S+ T P
Sbjct: 391 ICPAGPGYHYSASDLRYNTRPLGQEPPRVSLSQPRTLPATSRPSAGFLPTHRLEPRPEPR 450
Query: 1279 ADPYFIQDRFLNSFEEL---QAEECGILNG--------CENGRCVRVQEGYTCDCFDGYH 1327
DP + L S + E G +G C GRC+ GYTC C G+
Sbjct: 451 PDPRPGPELPLPSIPAWTGPEIPESGPSSGMCQRNPQVCGPGRCISRPSGYTCACDSGFR 510
Query: 1328 LDTAKMTCVDVNECDELNNRMSLCKNAKCINTDGSYKCLCLPGYVPSDKPNYCTPLNTAL 1387
L C+DV+EC + C +C N+ GS++C+C PG+ + C ++
Sbjct: 511 LSPQGTRCIDVDECRRVPPP---CAPGRCENSPGSFRCVCGPGFRAGPRAAECLDVDECH 567
Query: 1388 NLEKDSDL 1395
+ DL
Sbjct: 568 RVPPPCDL 575
Score = 69.7 bits (169), Expect = 2e-11
Identities = 30/85 (35%), Positives = 44/85 (51%), Gaps = 4/85 (4%)
Query: 754 DIDECQQGNLCVNGQCKNTEGSFRCTCGQGYQLSAAKDQCEDIDECQHRH----LCAHGQ 809
+ +EC + C NG+C F C C GY+L + C DI+EC LC + +
Sbjct: 1466 EAEECGILDGCTNGRCVRVPEGFTCRCFDGYRLDMTRMACVDINECDEAEAASPLCVNAR 1525
Query: 810 CRNTEGSFQCVCDQGYRASGLGDHC 834
C NT+GSF+C+C G+ + HC
Sbjct: 1526 CLNTDGSFRCICRPGFAPTHQPHHC 1550
Score = 66.6 bits (161), Expect = 2e-10
Identities = 31/86 (36%), Positives = 42/86 (48%), Gaps = 4/86 (4%)
Query: 712 LDVDECLEPNVCANGDCSNLEGSYMCSCHKGYTRTPDHKHCRDIDECQQGN----LCVNG 767
L+ +EC + C NG C + + C C GY C DI+EC + LCVN
Sbjct: 1465 LEAEECGILDGCTNGRCVRVPEGFTCRCFDGYRLDMTRMACVDINECDEAEAASPLCVNA 1524
Query: 768 QCKNTEGSFRCTCGQGYQLSAAKDQC 793
+C NT+GSFRC C G+ + C
Sbjct: 1525 RCLNTDGSFRCICRPGFAPTHQPHHC 1550
Score = 63.9 bits (154), Expect = 1e-09
Identities = 28/75 (37%), Positives = 39/75 (52%), Gaps = 4/75 (5%)
Query: 847 CQRGDCINTAGSYDCTCPDGFQLDDNK-TCQDINECEHPGLCGP---QGECLNTEGSFHC 902
C G C+ + C C DG++LD + C DINEC+ P CLNT+GSF C
Sbjct: 1476 CTNGRCVRVPEGFTCRCFDGYRLDMTRMACVDINECDEAEAASPLCVNARCLNTDGSFRC 1535
Query: 903 VCQQGFSISADGRTC 917
+C+ GF+ + C
Sbjct: 1536 ICRPGFAPTHQPHHC 1550
Score = 62.0 bits (149), Expect = 4e-09
Identities = 29/91 (31%), Positives = 50/91 (54%), Gaps = 8/91 (8%)
Query: 1084 PAGESSSEAGGENYKD--ADECLLFGQEICKNGFCLNTRPGYECYCKQGTYYDPVKLQCF 1141
P G S + + E Y++ A+EC + + C NG C+ G+ C C G D ++ C
Sbjct: 1449 PEGGSYAGSLAEPYEELEAEECGIL--DGCTNGRCVRVPEGFTCRCFDGYRLDMTRMACV 1506
Query: 1142 DMDECQDPSS----CIDGQCVNTEGSYNCFC 1168
D++EC + + C++ +C+NT+GS+ C C
Sbjct: 1507 DINECDEAEAASPLCVNARCLNTDGSFRCIC 1537
Score = 57.0 bits (136), Expect = 1e-07
Identities = 33/91 (36%), Positives = 43/91 (47%), Gaps = 4/91 (4%)
Query: 781 GQGYQLSAAKDQCE-DIDECQHRHLCAHGQCRNTEGSFQCVCDQGYRASGLGDHCEDINE 839
G Y S A+ E + +EC C +G+C F C C GYR C DINE
Sbjct: 1451 GGSYAGSLAEPYEELEAEECGILDGCTNGRCVRVPEGFTCRCFDGYRLDMTRMACVDINE 1510
Query: 840 CLEDKS---VCQRGDCINTAGSYDCTCPDGF 867
C E ++ +C C+NT GS+ C C GF
Sbjct: 1511 CDEAEAASPLCVNARCLNTDGSFRCICRPGF 1541
Score = 55.8 bits (133), Expect = 3e-07
Identities = 27/79 (34%), Positives = 36/79 (45%), Gaps = 10/79 (12%)
Query: 913 DGRTCEDIDECVNNTVCDSHGFCDNTAGSFRCLCYQGFQAPQDGQGCVDVNEC---ELLS 969
+ C +D C N G C F C C+ G++ CVD+NEC E S
Sbjct: 1466 EAEECGILDGCTN-------GRCVRVPEGFTCRCFDGYRLDMTRMACVDINECDEAEAAS 1518
Query: 970 GVCGEAFCENVEGSFLCVC 988
+C A C N +GSF C+C
Sbjct: 1519 PLCVNARCLNTDGSFRCIC 1537
Score = 52.0 bits (123), Expect = 4e-06
Identities = 26/64 (40%), Positives = 31/64 (48%), Gaps = 5/64 (7%)
Query: 286 CLPGYKR-VNNTFCQDINECQ----LQGVCPNGECLNTMGSYRCTCKIGFGPDPTFSSCV 340
C GY+ + C DINEC +C N CLNT GS+RC C+ GF P C
Sbjct: 1492 CFDGYRLDMTRMACVDINECDEAEAASPLCVNARCLNTDGSFRCICRPGFAPTHQPHHCA 1551
Query: 341 PDPP 344
P P
Sbjct: 1552 PARP 1555
Score = 50.8 bits (120), Expect = 9e-06
Identities = 28/79 (35%), Positives = 40/79 (50%), Gaps = 7/79 (8%)
Query: 631 IDVDECLRPDVCGEGHCVNTVGAFRCEYCDSGYRMTQ-RGRCEDIDECLNPST----CPD 685
++ +EC D C G CV F C C GYR+ R C DI+EC C +
Sbjct: 1465 LEAEECGILDGCTNGRCVRVPEGFTCR-CFDGYRLDMTRMACVDINECDEAEAASPLCVN 1523
Query: 686 EQCVNSPGSYQCVPCTEGF 704
+C+N+ GS++C+ C GF
Sbjct: 1524 ARCLNTDGSFRCI-CRPGF 1541
Score = 48.5 bits (114), Expect = 4e-05
Identities = 36/134 (26%), Positives = 55/134 (41%), Gaps = 28/134 (20%)
Query: 1211 CSRPLVGKQTTYTECCCLYGEAWGMQ-CALCPLKDSDDYAQLCNIPVTGRRQPYGRDALV 1269
C+ PL G +T CC G AWG+ C LC + G V
Sbjct: 231 CASPLPGLRTQEV-CCRGAGLAWGVHDCQLCS-------------------ERLGNSERV 270
Query: 1270 DFSEQYTPEADPYFIQDRFLNSFEELQAEECGILNGCENGRCVRVQEGYTCDCFDGYHLD 1329
+ P +R S E++ +EC C++G C + GYTC C DG+ LD
Sbjct: 271 SAPDGPCPTGF-----ERVNGSCEDV--DECATGGRCQHGECANTRGGYTCVCPDGFLLD 323
Query: 1330 TAKMTCVDVNECDE 1343
+++ +C+ + E
Sbjct: 324 SSRSSCISQHVISE 337
Score = 48.5 bits (114), Expect = 4e-05
Identities = 29/107 (27%), Positives = 46/107 (42%), Gaps = 12/107 (11%)
Query: 857 GSYDCTCPDGFQLDDNKTCQDINECEHPGLCGPQGECLNTEGSFHCVCQQGFSISADGRT 916
GSY + + ++ + + C ++ C + G C+ F C C G+ +
Sbjct: 1452 GSYAGSLAEPYEELEAEECGILDGCTN-------GRCVRVPEGFTCRCFDGYRLDMTRMA 1504
Query: 917 CEDIDEC----VNNTVCDSHGFCDNTAGSFRCLCYQGFQAPQDGQGC 959
C DI+EC + +C + C NT GSFRC+C GF C
Sbjct: 1505 CVDINECDEAEAASPLC-VNARCLNTDGSFRCICRPGFAPTHQPHHC 1550
>gi|110347412 latent transforming growth factor beta binding protein 4
isoform b [Homo sapiens]
Length = 1587
Score = 904 bits (2337), Expect = 0.0
Identities = 509/1300 (39%), Positives = 679/1300 (52%), Gaps = 166/1300 (12%)
Query: 75 VICHLPCMNGGQCSSRDKCQCPPNFTGKLCQIPVHGASVPKLYQHSQQPGKALGTHVIHS 134
V+C L C NGG C D+C CPP+F GK CQ+ GA P PG + S
Sbjct: 114 VLCPLICHNGGVCVKPDRCLCPPDFAGKFCQLHSSGARPPA----PAVPG------LTRS 163
Query: 135 THTLPLTV--TSQQGVKVKFPPNIVNIHVKHPPEASVQIHQVSRIDGPTGQKTKEAQPGQ 192
+T+PL + GV ++V++HV+HP EASV +HQV R+ GP + EA
Sbjct: 164 VYTMPLANHRDDEHGVA-----SMVSVHVEHPQEASVVVHQVERVSGPWEEADAEAVARA 218
Query: 193 SQVSYQGLPVQKTQTIHSTYSHQQVIPHVYPVAAKTQLGRCFQETIGSQCGKALPGLSKQ 252
+ T S P + + G CF+E G +C LPGL Q
Sbjct: 219 EAAARAEAAAPYTVLAQSA-------PREDGYSDASGFGYCFRELRGGECASPLPGLRTQ 271
Query: 253 EDCCGTVGTSWGFNKCQKCPKKPSYHGYNQMME-----CLPGYKRVNNTFCQDINECQLQ 307
E CC G +WG + CQ C ++ G ++ + C G++RVN + C+D++EC
Sbjct: 272 EVCCRGAGLAWGVHDCQLCSERL---GNSERVSAPDGPCPTGFERVNGS-CEDVDECATG 327
Query: 308 GVCPNGECLNTMGSYRCTCKIGFGPDPTFSSCVPDPPVISEEKGPCYRLVSSGRQCMHPL 367
G C +GEC NT G Y C C GF D + SSC+ VISE KGPC+R++ G C P+
Sbjct: 328 GRCQHGECANTRGGYTCVCPDGFLLDSSRSSCISQH-VISEAKGPCFRVLRDGG-CSLPI 385
Query: 368 SVHLTKQLCCCS-VGKAWGPHCEKCPLPGTAAFKEICPGGMGYTVSGVHRR---RPIHHH 423
++TKQ+CCCS VGKAWG C+ CP G+ F+EICP G GY S R RP+
Sbjct: 386 LRNITKQICCCSRVGKAWGRGCQLCPPFGSEGFREICPAGPGYHYSASDLRYNTRPLGQE 445
Query: 424 ---VGKGPVFVKPKNTQPVAK--STH---------PPPLPAKEEPVEALTFSR-----EH 464
V P ++P A TH P P P E P+ ++ E
Sbjct: 446 PPRVSLSQPRTLPATSRPSAGFLPTHRLEPRPEPRPDPRPGPELPLPSIPAWTGPEIPES 505
Query: 465 GP--GVAEPEVATAPPEKEI--PS-------------------LDQEKTK-----LEPGQ 496
GP G+ + P + I PS +D ++ + PG+
Sbjct: 506 GPSSGMCQRNPQVCGPGRCISRPSGYTCACDSGFRLSPQGTRCIDVDECRRVPPPCAPGR 565
Query: 497 PQLSPGISTIHLHPQFPG--------IVIEKTSPPVPVEVAPEASTSSASQVIAPT---- 544
+ SPG P F V E P P ++ +T + + P
Sbjct: 566 CENSPGSFRCVCGPGFRAGPRAAECLDVDECHRVPPPCDLGRCENTPGSFLCVCPAGYQA 625
Query: 545 -----QVTEINECTVNPDICGAGHCINLPVRYTCICYEGYRFSEQQRKCVDIDECTQVQH 599
+++ECT +P +CG G C NLP + C+C G+R S + D+DEC Q
Sbjct: 626 APHGASCQDVDECTQSPGLCGRGACKNLPGSFRCVCPAGFRGSACEE---DVDECAQEPP 682
Query: 600 LCSQGRCENTEGSFLCICPAGFMASEEGTNCIDVDECLR-PDVCGEGHCVNTVGAFRCEY 658
C GRC+NT GSF C CPAGF + G C DVDEC R P C G C NT G+F+C
Sbjct: 683 PCGPGRCDNTAGSFHCACPAGFRSRGPGAPCQDVDECARSPPPCTYGRCENTEGSFQC-V 741
Query: 659 CDSGYRMTQRG-RCEDIDECLNPSTCPDEQCVNSPGSYQCVPCTEGFRGWNGQCLDVDEC 717
C G++ G CED+DEC N CP ++CVNSPGS+QC C G G+C DVDEC
Sbjct: 742 CPMGFQPNTAGSECEDVDECENHLACPGQECVNSPGSFQCRTCPSGHHLHRGRCTDVDEC 801
Query: 718 LE--PNVCANGDCSNLEGSYMCSCHKGYTRTPDHKH--CRDIDECQQGNLCV-NGQCKNT 772
P +G C+N EGS+ CSC GY R P + C D++EC +G+ C +G+C NT
Sbjct: 802 SSGAPPCGPHGHCTNTEGSFRCSCAPGY-RAPSGRPGPCADVNECLEGDFCFPHGECLNT 860
Query: 773 EGSFRCTCGQGYQLSAAKDQCEDIDECQHRHLCAHGQCRNTEGSFQCVCDQGYRASGLGD 832
+GSF CTC GY+ C D+DEC LC G C NT+GSF+C+C G+RA
Sbjct: 861 DGSFACTCAPGYRPGPRGASCLDVDECSEEDLCQSGICTNTDGSFECICPPGHRAGPDLA 920
Query: 833 HCEDINECLE-DKSVCQRGDCINTAGSYDCT--CPDGFQLDDNKTCQDINECEH--PGLC 887
C D++EC E ++C C N+ GSY C C G+ TC D++EC+ P +C
Sbjct: 921 SCLDVDECRERGPALCGSQRCENSPGSYRCVRDCDPGYHAGPEGTCDDVDECQEYGPEIC 980
Query: 888 GPQGECLNTEGSFHCV--CQQGFSISADGRTCEDIDECVNNTVCDSHGFCDNTAGSFRCL 945
G Q C NT GS+ C C G+ + G C+D+DEC N + C +H C N GSF+CL
Sbjct: 981 GAQ-RCENTPGSYRCTPACDPGYQPTPGGG-CQDVDECRNRSFCGAHAVCQNLPGSFQCL 1038
Query: 946 CYQGFQAPQDGQGCVDVNECELLSGVCGEAFCENVEGSFLCVCADENQEYSPMTGQCRSR 1005
C QG++ +DG+ CVDVNECE L GVCG A CENVEGSFLCVC + +E+ PMTG+C
Sbjct: 1039 CDQGYEGARDGRHCVDVNECETLQGVCGAALCENVEGSFLCVCPNSPEEFDPMTGRCVPP 1098
Query: 1006 TSTDLDVDVDQPKEE-----------------------------KKECYYNLNDASLCDN 1036
++ QP+ ++ECY++ CDN
Sbjct: 1099 RTSAGTFPGSQPQAPASPVLPARPPPPPLPRRPSTPRQGPVGSGRRECYFDTAAPDACDN 1158
Query: 1037 VLAPNVTKQECCCTSGAGWGDNCEIFPCPVLGTAEFTEMCPKGKGFV-PAGESSSEAGGE 1095
+LA NVT QECCCT G GWG C I CP TAE+ +CP G+G++ P+G+ S
Sbjct: 1159 ILARNVTWQECCCTVGEGWGSGCRIQQCPGTETAEYQSLCPHGRGYLAPSGDLSLR---- 1214
Query: 1096 NYKDADECLLFGQEICKNGFCLNTRPGYECYCKQGTYYDPVKLQCFDMDECQDPS-SCID 1154
+D DEC LF ++CK+G C+NT PGY CYC G YY +L+C D DEC D +C
Sbjct: 1215 --RDVDECQLFRDQVCKSGVCVNTAPGYSCYCSNGYYYHTQRLECIDNDECADEEPACEG 1272
Query: 1155 GQCVNTEGSYNCFCTHPMVLDASEKRCIRPAESNEQIEETDVYQDLCWEHLSDEYVCSRP 1214
G+CVNT GSY+C C P+VLD S++RC+ SNE + D +CW+ + + VCS P
Sbjct: 1273 GRCVNTVGSYHCTCEPPLVLDGSQRRCV----SNES-QSLDDNLGVCWQEVGADLVCSHP 1327
Query: 1215 LVGKQTTYTECCCLYGEAWGMQCALCPLKDSDDYAQLCNI 1254
+ +Q TYTECCCLYGEAWGM CALCP +DSDD+ LCN+
Sbjct: 1328 RLDRQATYTECCCLYGEAWGMDCALCPAQDSDDFEALCNV 1367
Score = 257 bits (657), Expect = 5e-68
Identities = 205/647 (31%), Positives = 265/647 (40%), Gaps = 110/647 (17%)
Query: 758 CQQG-NLCVNGQCKNTEGSFRCTCGQGYQLSAAKDQCEDIDECQH-RHLCAHGQCRNTEG 815
CQ+ +C G+C + + C C G++LS +C D+DEC+ CA G+C N+ G
Sbjct: 512 CQRNPQVCGPGRCISRPSGYTCACDSGFRLSPQGTRCIDVDECRRVPPPCAPGRCENSPG 571
Query: 816 SFQCVCDQGYRASGLGDHCEDINECLEDKSVCQRGDCINTAGSYDCTCPDGFQLDDN-KT 874
SF+CVC G+RA C D++EC C G C NT GS+ C CP G+Q + +
Sbjct: 572 SFRCVCGPGFRAGPRAAECLDVDECHRVPPPCDLGRCENTPGSFLCVCPAGYQAAPHGAS 631
Query: 875 CQDINEC-EHPGLCGPQGECLNTEGSFHCVCQQGFSISADGRTCE-DIDECVNNTVCDSH 932
CQD++EC + PGLCG +G C N GSF CVC GF G CE D+DEC
Sbjct: 632 CQDVDECTQSPGLCG-RGACKNLPGSFRCVCPAGFR----GSACEEDVDECAQEPPPCGP 686
Query: 933 GFCDNTAGSFRCLCYQGFQAPQDGQGCVDVNECELLSGVCGEAFCENVEGSFLCVCADEN 992
G CDNTAGSF C C GF++ G C DV+EC C CEN EGSF CVC
Sbjct: 687 GRCDNTAGSFHCACPAGFRSRGPGAPCQDVDECARSPPPCTYGRCENTEGSFQCVC---- 742
Query: 993 QEYSPMTGQCRSRTSTDLDVDVDQPKEEKKECYYNLNDASLCDNVLAPNVTKQECCCTSG 1052
PM Q P EC D C+N LA QEC + G
Sbjct: 743 ----PMGFQ---------------PNTAGSEC----EDVDECENHLA--CPGQECVNSPG 777
Query: 1053 AGWGDNCEIFPCPVLGTAEFTEMCPKGKGFVPAGESSSEAGGENYKDADECLLFGQEICK 1112
+ F C CP G + G + D DEC
Sbjct: 778 S--------FQC---------RTCPSGH-HLHRGRCT---------DVDECSSGAPPCGP 810
Query: 1113 NGFCLNTRPGYECYCKQGTYYDPVKLQ--CFDMDECQDPSSCID-GQCVNTEGSYNCFCT 1169
+G C NT + C C G Y P C D++EC + C G+C+NT+GS+ C C
Sbjct: 811 HGHCTNTEGSFRCSCAPG-YRAPSGRPGPCADVNECLEGDFCFPHGECLNTDGSFACTCA 869
Query: 1170 HPMVLDASEKRCIRPAESNEQIEETDVYQDLCWEHLSDEYVCSRPLVGKQTTYTECCCLY 1229
RP + D S+E +C + EC C
Sbjct: 870 PGY----------RPGPRGASCLDVD--------ECSEEDLCQSGICTNTDGSFECICPP 911
Query: 1230 GEAWGMQCALCPLKDSDDYAQ----LCNIPVTGRRQPYGRDALVDFSEQYTPEADPYFIQ 1285
G G A C D D+ + LC P + D Y A P
Sbjct: 912 GHRAGPDLASC--LDVDECRERGPALCGSQRC-ENSPGSYRCVRDCDPGY--HAGPEGTC 966
Query: 1286 DRFLNSFEELQAEECGILNGCENGRCVRVQEGYTCD--CFDGYHLDTAKMTCVDVNECDE 1343
D ++ +E E CG RC Y C C GY T C DV+EC
Sbjct: 967 DD-VDECQEYGPEICGAQ------RCENTPGSYRCTPACDPGYQ-PTPGGGCQDVDEC-- 1016
Query: 1344 LNNRMSLCKNAKCINTDGSYKCLCLPGYVPSDKPNYCTPLNTALNLE 1390
NR +A C N GS++CLC GY + +C +N L+
Sbjct: 1017 -RNRSFCGAHAVCQNLPGSFQCLCDQGYEGARDGRHCVDVNECETLQ 1062
Score = 153 bits (386), Expect = 1e-36
Identities = 127/463 (27%), Positives = 176/463 (38%), Gaps = 93/463 (20%)
Query: 233 CFQETIGSQ-CGKALPGLSKQEDCCGTVGTSWGFN-KCQKCPKK---------PSYHGY- 280
C+ +T C L ++CC TVG WG + Q+CP P GY
Sbjct: 1146 CYFDTAAPDACDNILARNVTWQECCCTVGEGWGSGCRIQQCPGTETAEYQSLCPHGRGYL 1205
Query: 281 ---------NQMMEC----------------LPGYK---------RVNNTFCQDINEC-Q 305
+ EC PGY C D +EC
Sbjct: 1206 APSGDLSLRRDVDECQLFRDQVCKSGVCVNTAPGYSCYCSNGYYYHTQRLECIDNDECAD 1265
Query: 306 LQGVCPNGECLNTMGSYRCTCKIGFGPDPTFSSCVP-DPPVISEEKGPCYRLVSSGRQCM 364
+ C G C+NT+GSY CTC+ D + CV + + + G C++ V + C
Sbjct: 1266 EEPACEGGRCVNTVGSYHCTCEPPLVLDGSQRRCVSNESQSLDDNLGVCWQEVGADLVCS 1325
Query: 365 HP-LSVHLTKQLCCCSVGKAWGPHCEKCPLPGTAAFKEIC------------PGGMGYTV 411
HP L T CCC G+AWG C CP + F+ +C PGG G
Sbjct: 1326 HPRLDRQATYTECCCLYGEAWGMDCALCPAQDSDDFEALCNVLRPPAYSPPRPGGFGL-- 1383
Query: 412 SGVHRRRPIHHHVGKGPVFVKPKNTQPVAKSTHPPP-LPAKEEPVEALTFSREHGPGVAE 470
P + GP P P +PPP LP P F+R P A
Sbjct: 1384 -------PYEYGPDLGP----PYQGLPYGPELYPPPALPYDPYPPPPGPFARREAPYGA- 1431
Query: 471 PEVATAPPEKEIPSLDQEKTKLEPGQPQLSPGISTIHLHPQFPGIVIEKTSPPVPVEVAP 530
P ++P + + + PG T + + S P P E P
Sbjct: 1432 -------PRFDMPDFEDDGGPYGESEAPAPPGPGTRWPYRSRD----TRRSFPEPEE--P 1478
Query: 531 EASTSSASQVIAPTQVTEINECTVNPDICGAGHCINLPVRYTCICYEGYRFSEQQRKCVD 590
S A + P + E EC + D C G C+ +P +TC C++GYR + CVD
Sbjct: 1479 PEGGSYAGSLAEPYEELEAEECGIL-DGCTNGRCVRVPEGFTCRCFDGYRLDMTRMACVD 1537
Query: 591 IDECTQVQ---HLCSQGRCENTEGSFLCICPAGFMASEEGTNC 630
I+EC + + LC RC NT+GSF CIC GF + + +C
Sbjct: 1538 INECDEAEAASPLCVNARCLNTDGSFRCICRPGFAPTHQPHHC 1580
Score = 151 bits (381), Expect = 5e-36
Identities = 69/130 (53%), Positives = 86/130 (66%), Gaps = 4/130 (3%)
Query: 1255 PVTGRRQPY-GRDALVDFSE-QYTPEADPYFIQDRFLNSFEELQAEECGILNGCENGRCV 1312
P G R PY RD F E + PE Y +EEL+AEECGIL+GC NGRCV
Sbjct: 1455 PGPGTRWPYRSRDTRRSFPEPEEPPEGGSY--AGSLAEPYEELEAEECGILDGCTNGRCV 1512
Query: 1313 RVQEGYTCDCFDGYHLDTAKMTCVDVNECDELNNRMSLCKNAKCINTDGSYKCLCLPGYV 1372
RV EG+TC CFDGY LD +M CVD+NECDE LC NA+C+NTDGS++C+C PG+
Sbjct: 1513 RVPEGFTCRCFDGYRLDMTRMACVDINECDEAEAASPLCVNARCLNTDGSFRCICRPGFA 1572
Query: 1373 PSDKPNYCTP 1382
P+ +P++C P
Sbjct: 1573 PTHQPHHCAP 1582
Score = 110 bits (276), Expect = 7e-24
Identities = 84/308 (27%), Positives = 122/308 (39%), Gaps = 54/308 (17%)
Query: 1131 TYYDPVKLQCFDMDECQDPSSCIDGQCVNTEGSYNCFCTHPMVLDASEKRCIRPAESNEQ 1190
T ++ V C D+DEC C G+C NT G Y C C +LD+S CI S
Sbjct: 309 TGFERVNGSCEDVDECATGGRCQHGECANTRGGYTCVCPDGFLLDSSRSSCI----SQHV 364
Query: 1191 IEETDVYQDLCWEHLSDEYVCSRPLVGKQTTYTECCCLYGEAWGMQCALCPLKDSDDYAQ 1250
I E + C+ L D CS P++ T CC G+AWG C LCP S+ + +
Sbjct: 365 ISEA---KGPCFRVLRDGG-CSLPILRNITKQICCCSRVGKAWGRGCQLCPPFGSEGFRE 420
Query: 1251 LCNI---------PVTGRRQPYGRDA-LVDFSEQYT----------------------PE 1278
+C + +P G++ V S+ T P
Sbjct: 421 ICPAGPGYHYSASDLRYNTRPLGQEPPRVSLSQPRTLPATSRPSAGFLPTHRLEPRPEPR 480
Query: 1279 ADPYFIQDRFLNSFEEL---QAEECGILNG--------CENGRCVRVQEGYTCDCFDGYH 1327
DP + L S + E G +G C GRC+ GYTC C G+
Sbjct: 481 PDPRPGPELPLPSIPAWTGPEIPESGPSSGMCQRNPQVCGPGRCISRPSGYTCACDSGFR 540
Query: 1328 LDTAKMTCVDVNECDELNNRMSLCKNAKCINTDGSYKCLCLPGYVPSDKPNYCTPLNTAL 1387
L C+DV+EC + C +C N+ GS++C+C PG+ + C ++
Sbjct: 541 LSPQGTRCIDVDECRRVPPP---CAPGRCENSPGSFRCVCGPGFRAGPRAAECLDVDECH 597
Query: 1388 NLEKDSDL 1395
+ DL
Sbjct: 598 RVPPPCDL 605
Score = 69.7 bits (169), Expect = 2e-11
Identities = 30/85 (35%), Positives = 44/85 (51%), Gaps = 4/85 (4%)
Query: 754 DIDECQQGNLCVNGQCKNTEGSFRCTCGQGYQLSAAKDQCEDIDECQHRH----LCAHGQ 809
+ +EC + C NG+C F C C GY+L + C DI+EC LC + +
Sbjct: 1496 EAEECGILDGCTNGRCVRVPEGFTCRCFDGYRLDMTRMACVDINECDEAEAASPLCVNAR 1555
Query: 810 CRNTEGSFQCVCDQGYRASGLGDHC 834
C NT+GSF+C+C G+ + HC
Sbjct: 1556 CLNTDGSFRCICRPGFAPTHQPHHC 1580
Score = 66.6 bits (161), Expect = 2e-10
Identities = 31/86 (36%), Positives = 42/86 (48%), Gaps = 4/86 (4%)
Query: 712 LDVDECLEPNVCANGDCSNLEGSYMCSCHKGYTRTPDHKHCRDIDECQQGN----LCVNG 767
L+ +EC + C NG C + + C C GY C DI+EC + LCVN
Sbjct: 1495 LEAEECGILDGCTNGRCVRVPEGFTCRCFDGYRLDMTRMACVDINECDEAEAASPLCVNA 1554
Query: 768 QCKNTEGSFRCTCGQGYQLSAAKDQC 793
+C NT+GSFRC C G+ + C
Sbjct: 1555 RCLNTDGSFRCICRPGFAPTHQPHHC 1580
Score = 63.9 bits (154), Expect = 1e-09
Identities = 28/75 (37%), Positives = 39/75 (52%), Gaps = 4/75 (5%)
Query: 847 CQRGDCINTAGSYDCTCPDGFQLDDNK-TCQDINECEHPGLCGP---QGECLNTEGSFHC 902
C G C+ + C C DG++LD + C DINEC+ P CLNT+GSF C
Sbjct: 1506 CTNGRCVRVPEGFTCRCFDGYRLDMTRMACVDINECDEAEAASPLCVNARCLNTDGSFRC 1565
Query: 903 VCQQGFSISADGRTC 917
+C+ GF+ + C
Sbjct: 1566 ICRPGFAPTHQPHHC 1580
Score = 62.0 bits (149), Expect = 4e-09
Identities = 29/91 (31%), Positives = 50/91 (54%), Gaps = 8/91 (8%)
Query: 1084 PAGESSSEAGGENYKD--ADECLLFGQEICKNGFCLNTRPGYECYCKQGTYYDPVKLQCF 1141
P G S + + E Y++ A+EC + + C NG C+ G+ C C G D ++ C
Sbjct: 1479 PEGGSYAGSLAEPYEELEAEECGIL--DGCTNGRCVRVPEGFTCRCFDGYRLDMTRMACV 1536
Query: 1142 DMDECQDPSS----CIDGQCVNTEGSYNCFC 1168
D++EC + + C++ +C+NT+GS+ C C
Sbjct: 1537 DINECDEAEAASPLCVNARCLNTDGSFRCIC 1567
Score = 57.0 bits (136), Expect = 1e-07
Identities = 33/91 (36%), Positives = 43/91 (47%), Gaps = 4/91 (4%)
Query: 781 GQGYQLSAAKDQCE-DIDECQHRHLCAHGQCRNTEGSFQCVCDQGYRASGLGDHCEDINE 839
G Y S A+ E + +EC C +G+C F C C GYR C DINE
Sbjct: 1481 GGSYAGSLAEPYEELEAEECGILDGCTNGRCVRVPEGFTCRCFDGYRLDMTRMACVDINE 1540
Query: 840 CLEDKS---VCQRGDCINTAGSYDCTCPDGF 867
C E ++ +C C+NT GS+ C C GF
Sbjct: 1541 CDEAEAASPLCVNARCLNTDGSFRCICRPGF 1571
Score = 55.8 bits (133), Expect = 3e-07
Identities = 27/79 (34%), Positives = 36/79 (45%), Gaps = 10/79 (12%)
Query: 913 DGRTCEDIDECVNNTVCDSHGFCDNTAGSFRCLCYQGFQAPQDGQGCVDVNEC---ELLS 969
+ C +D C N G C F C C+ G++ CVD+NEC E S
Sbjct: 1496 EAEECGILDGCTN-------GRCVRVPEGFTCRCFDGYRLDMTRMACVDINECDEAEAAS 1548
Query: 970 GVCGEAFCENVEGSFLCVC 988
+C A C N +GSF C+C
Sbjct: 1549 PLCVNARCLNTDGSFRCIC 1567
Score = 52.0 bits (123), Expect = 4e-06
Identities = 26/64 (40%), Positives = 31/64 (48%), Gaps = 5/64 (7%)
Query: 286 CLPGYKR-VNNTFCQDINECQ----LQGVCPNGECLNTMGSYRCTCKIGFGPDPTFSSCV 340
C GY+ + C DINEC +C N CLNT GS+RC C+ GF P C
Sbjct: 1522 CFDGYRLDMTRMACVDINECDEAEAASPLCVNARCLNTDGSFRCICRPGFAPTHQPHHCA 1581
Query: 341 PDPP 344
P P
Sbjct: 1582 PARP 1585
Score = 50.8 bits (120), Expect = 9e-06
Identities = 28/79 (35%), Positives = 40/79 (50%), Gaps = 7/79 (8%)
Query: 631 IDVDECLRPDVCGEGHCVNTVGAFRCEYCDSGYRMTQ-RGRCEDIDECLNPST----CPD 685
++ +EC D C G CV F C C GYR+ R C DI+EC C +
Sbjct: 1495 LEAEECGILDGCTNGRCVRVPEGFTCR-CFDGYRLDMTRMACVDINECDEAEAASPLCVN 1553
Query: 686 EQCVNSPGSYQCVPCTEGF 704
+C+N+ GS++C+ C GF
Sbjct: 1554 ARCLNTDGSFRCI-CRPGF 1571
Score = 48.5 bits (114), Expect = 4e-05
Identities = 36/134 (26%), Positives = 55/134 (41%), Gaps = 28/134 (20%)
Query: 1211 CSRPLVGKQTTYTECCCLYGEAWGMQ-CALCPLKDSDDYAQLCNIPVTGRRQPYGRDALV 1269
C+ PL G +T CC G AWG+ C LC + G V
Sbjct: 261 CASPLPGLRTQEV-CCRGAGLAWGVHDCQLCS-------------------ERLGNSERV 300
Query: 1270 DFSEQYTPEADPYFIQDRFLNSFEELQAEECGILNGCENGRCVRVQEGYTCDCFDGYHLD 1329
+ P +R S E++ +EC C++G C + GYTC C DG+ LD
Sbjct: 301 SAPDGPCPTGF-----ERVNGSCEDV--DECATGGRCQHGECANTRGGYTCVCPDGFLLD 353
Query: 1330 TAKMTCVDVNECDE 1343
+++ +C+ + E
Sbjct: 354 SSRSSCISQHVISE 367
Score = 48.5 bits (114), Expect = 4e-05
Identities = 29/107 (27%), Positives = 46/107 (42%), Gaps = 12/107 (11%)
Query: 857 GSYDCTCPDGFQLDDNKTCQDINECEHPGLCGPQGECLNTEGSFHCVCQQGFSISADGRT 916
GSY + + ++ + + C ++ C + G C+ F C C G+ +
Sbjct: 1482 GSYAGSLAEPYEELEAEECGILDGCTN-------GRCVRVPEGFTCRCFDGYRLDMTRMA 1534
Query: 917 CEDIDEC----VNNTVCDSHGFCDNTAGSFRCLCYQGFQAPQDGQGC 959
C DI+EC + +C + C NT GSFRC+C GF C
Sbjct: 1535 CVDINECDEAEAASPLC-VNARCLNTDGSFRCICRPGFAPTHQPHHC 1580
>gi|110347431 latent transforming growth factor beta binding protein 4
isoform a [Homo sapiens]
Length = 1624
Score = 904 bits (2337), Expect = 0.0
Identities = 509/1300 (39%), Positives = 679/1300 (52%), Gaps = 166/1300 (12%)
Query: 75 VICHLPCMNGGQCSSRDKCQCPPNFTGKLCQIPVHGASVPKLYQHSQQPGKALGTHVIHS 134
V+C L C NGG C D+C CPP+F GK CQ+ GA P PG + S
Sbjct: 151 VLCPLICHNGGVCVKPDRCLCPPDFAGKFCQLHSSGARPPA----PAVPG------LTRS 200
Query: 135 THTLPLTV--TSQQGVKVKFPPNIVNIHVKHPPEASVQIHQVSRIDGPTGQKTKEAQPGQ 192
+T+PL + GV ++V++HV+HP EASV +HQV R+ GP + EA
Sbjct: 201 VYTMPLANHRDDEHGVA-----SMVSVHVEHPQEASVVVHQVERVSGPWEEADAEAVARA 255
Query: 193 SQVSYQGLPVQKTQTIHSTYSHQQVIPHVYPVAAKTQLGRCFQETIGSQCGKALPGLSKQ 252
+ T S P + + G CF+E G +C LPGL Q
Sbjct: 256 EAAARAEAAAPYTVLAQSA-------PREDGYSDASGFGYCFRELRGGECASPLPGLRTQ 308
Query: 253 EDCCGTVGTSWGFNKCQKCPKKPSYHGYNQMME-----CLPGYKRVNNTFCQDINECQLQ 307
E CC G +WG + CQ C ++ G ++ + C G++RVN + C+D++EC
Sbjct: 309 EVCCRGAGLAWGVHDCQLCSERL---GNSERVSAPDGPCPTGFERVNGS-CEDVDECATG 364
Query: 308 GVCPNGECLNTMGSYRCTCKIGFGPDPTFSSCVPDPPVISEEKGPCYRLVSSGRQCMHPL 367
G C +GEC NT G Y C C GF D + SSC+ VISE KGPC+R++ G C P+
Sbjct: 365 GRCQHGECANTRGGYTCVCPDGFLLDSSRSSCISQH-VISEAKGPCFRVLRDGG-CSLPI 422
Query: 368 SVHLTKQLCCCS-VGKAWGPHCEKCPLPGTAAFKEICPGGMGYTVSGVHRR---RPIHHH 423
++TKQ+CCCS VGKAWG C+ CP G+ F+EICP G GY S R RP+
Sbjct: 423 LRNITKQICCCSRVGKAWGRGCQLCPPFGSEGFREICPAGPGYHYSASDLRYNTRPLGQE 482
Query: 424 ---VGKGPVFVKPKNTQPVAK--STH---------PPPLPAKEEPVEALTFSR-----EH 464
V P ++P A TH P P P E P+ ++ E
Sbjct: 483 PPRVSLSQPRTLPATSRPSAGFLPTHRLEPRPEPRPDPRPGPELPLPSIPAWTGPEIPES 542
Query: 465 GP--GVAEPEVATAPPEKEI--PS-------------------LDQEKTK-----LEPGQ 496
GP G+ + P + I PS +D ++ + PG+
Sbjct: 543 GPSSGMCQRNPQVCGPGRCISRPSGYTCACDSGFRLSPQGTRCIDVDECRRVPPPCAPGR 602
Query: 497 PQLSPGISTIHLHPQFPG--------IVIEKTSPPVPVEVAPEASTSSASQVIAPT---- 544
+ SPG P F V E P P ++ +T + + P
Sbjct: 603 CENSPGSFRCVCGPGFRAGPRAAECLDVDECHRVPPPCDLGRCENTPGSFLCVCPAGYQA 662
Query: 545 -----QVTEINECTVNPDICGAGHCINLPVRYTCICYEGYRFSEQQRKCVDIDECTQVQH 599
+++ECT +P +CG G C NLP + C+C G+R S + D+DEC Q
Sbjct: 663 APHGASCQDVDECTQSPGLCGRGACKNLPGSFRCVCPAGFRGSACEE---DVDECAQEPP 719
Query: 600 LCSQGRCENTEGSFLCICPAGFMASEEGTNCIDVDECLR-PDVCGEGHCVNTVGAFRCEY 658
C GRC+NT GSF C CPAGF + G C DVDEC R P C G C NT G+F+C
Sbjct: 720 PCGPGRCDNTAGSFHCACPAGFRSRGPGAPCQDVDECARSPPPCTYGRCENTEGSFQC-V 778
Query: 659 CDSGYRMTQRG-RCEDIDECLNPSTCPDEQCVNSPGSYQCVPCTEGFRGWNGQCLDVDEC 717
C G++ G CED+DEC N CP ++CVNSPGS+QC C G G+C DVDEC
Sbjct: 779 CPMGFQPNTAGSECEDVDECENHLACPGQECVNSPGSFQCRTCPSGHHLHRGRCTDVDEC 838
Query: 718 LE--PNVCANGDCSNLEGSYMCSCHKGYTRTPDHKH--CRDIDECQQGNLCV-NGQCKNT 772
P +G C+N EGS+ CSC GY R P + C D++EC +G+ C +G+C NT
Sbjct: 839 SSGAPPCGPHGHCTNTEGSFRCSCAPGY-RAPSGRPGPCADVNECLEGDFCFPHGECLNT 897
Query: 773 EGSFRCTCGQGYQLSAAKDQCEDIDECQHRHLCAHGQCRNTEGSFQCVCDQGYRASGLGD 832
+GSF CTC GY+ C D+DEC LC G C NT+GSF+C+C G+RA
Sbjct: 898 DGSFACTCAPGYRPGPRGASCLDVDECSEEDLCQSGICTNTDGSFECICPPGHRAGPDLA 957
Query: 833 HCEDINECLE-DKSVCQRGDCINTAGSYDCT--CPDGFQLDDNKTCQDINECEH--PGLC 887
C D++EC E ++C C N+ GSY C C G+ TC D++EC+ P +C
Sbjct: 958 SCLDVDECRERGPALCGSQRCENSPGSYRCVRDCDPGYHAGPEGTCDDVDECQEYGPEIC 1017
Query: 888 GPQGECLNTEGSFHCV--CQQGFSISADGRTCEDIDECVNNTVCDSHGFCDNTAGSFRCL 945
G Q C NT GS+ C C G+ + G C+D+DEC N + C +H C N GSF+CL
Sbjct: 1018 GAQ-RCENTPGSYRCTPACDPGYQPTPGGG-CQDVDECRNRSFCGAHAVCQNLPGSFQCL 1075
Query: 946 CYQGFQAPQDGQGCVDVNECELLSGVCGEAFCENVEGSFLCVCADENQEYSPMTGQCRSR 1005
C QG++ +DG+ CVDVNECE L GVCG A CENVEGSFLCVC + +E+ PMTG+C
Sbjct: 1076 CDQGYEGARDGRHCVDVNECETLQGVCGAALCENVEGSFLCVCPNSPEEFDPMTGRCVPP 1135
Query: 1006 TSTDLDVDVDQPKEE-----------------------------KKECYYNLNDASLCDN 1036
++ QP+ ++ECY++ CDN
Sbjct: 1136 RTSAGTFPGSQPQAPASPVLPARPPPPPLPRRPSTPRQGPVGSGRRECYFDTAAPDACDN 1195
Query: 1037 VLAPNVTKQECCCTSGAGWGDNCEIFPCPVLGTAEFTEMCPKGKGFV-PAGESSSEAGGE 1095
+LA NVT QECCCT G GWG C I CP TAE+ +CP G+G++ P+G+ S
Sbjct: 1196 ILARNVTWQECCCTVGEGWGSGCRIQQCPGTETAEYQSLCPHGRGYLAPSGDLSLR---- 1251
Query: 1096 NYKDADECLLFGQEICKNGFCLNTRPGYECYCKQGTYYDPVKLQCFDMDECQDPS-SCID 1154
+D DEC LF ++CK+G C+NT PGY CYC G YY +L+C D DEC D +C
Sbjct: 1252 --RDVDECQLFRDQVCKSGVCVNTAPGYSCYCSNGYYYHTQRLECIDNDECADEEPACEG 1309
Query: 1155 GQCVNTEGSYNCFCTHPMVLDASEKRCIRPAESNEQIEETDVYQDLCWEHLSDEYVCSRP 1214
G+CVNT GSY+C C P+VLD S++RC+ SNE + D +CW+ + + VCS P
Sbjct: 1310 GRCVNTVGSYHCTCEPPLVLDGSQRRCV----SNES-QSLDDNLGVCWQEVGADLVCSHP 1364
Query: 1215 LVGKQTTYTECCCLYGEAWGMQCALCPLKDSDDYAQLCNI 1254
+ +Q TYTECCCLYGEAWGM CALCP +DSDD+ LCN+
Sbjct: 1365 RLDRQATYTECCCLYGEAWGMDCALCPAQDSDDFEALCNV 1404
Score = 257 bits (657), Expect = 5e-68
Identities = 205/647 (31%), Positives = 265/647 (40%), Gaps = 110/647 (17%)
Query: 758 CQQG-NLCVNGQCKNTEGSFRCTCGQGYQLSAAKDQCEDIDECQH-RHLCAHGQCRNTEG 815
CQ+ +C G+C + + C C G++LS +C D+DEC+ CA G+C N+ G
Sbjct: 549 CQRNPQVCGPGRCISRPSGYTCACDSGFRLSPQGTRCIDVDECRRVPPPCAPGRCENSPG 608
Query: 816 SFQCVCDQGYRASGLGDHCEDINECLEDKSVCQRGDCINTAGSYDCTCPDGFQLDDN-KT 874
SF+CVC G+RA C D++EC C G C NT GS+ C CP G+Q + +
Sbjct: 609 SFRCVCGPGFRAGPRAAECLDVDECHRVPPPCDLGRCENTPGSFLCVCPAGYQAAPHGAS 668
Query: 875 CQDINEC-EHPGLCGPQGECLNTEGSFHCVCQQGFSISADGRTCE-DIDECVNNTVCDSH 932
CQD++EC + PGLCG +G C N GSF CVC GF G CE D+DEC
Sbjct: 669 CQDVDECTQSPGLCG-RGACKNLPGSFRCVCPAGFR----GSACEEDVDECAQEPPPCGP 723
Query: 933 GFCDNTAGSFRCLCYQGFQAPQDGQGCVDVNECELLSGVCGEAFCENVEGSFLCVCADEN 992
G CDNTAGSF C C GF++ G C DV+EC C CEN EGSF CVC
Sbjct: 724 GRCDNTAGSFHCACPAGFRSRGPGAPCQDVDECARSPPPCTYGRCENTEGSFQCVC---- 779
Query: 993 QEYSPMTGQCRSRTSTDLDVDVDQPKEEKKECYYNLNDASLCDNVLAPNVTKQECCCTSG 1052
PM Q P EC D C+N LA QEC + G
Sbjct: 780 ----PMGFQ---------------PNTAGSEC----EDVDECENHLA--CPGQECVNSPG 814
Query: 1053 AGWGDNCEIFPCPVLGTAEFTEMCPKGKGFVPAGESSSEAGGENYKDADECLLFGQEICK 1112
+ F C CP G + G + D DEC
Sbjct: 815 S--------FQC---------RTCPSGH-HLHRGRCT---------DVDECSSGAPPCGP 847
Query: 1113 NGFCLNTRPGYECYCKQGTYYDPVKLQ--CFDMDECQDPSSCID-GQCVNTEGSYNCFCT 1169
+G C NT + C C G Y P C D++EC + C G+C+NT+GS+ C C
Sbjct: 848 HGHCTNTEGSFRCSCAPG-YRAPSGRPGPCADVNECLEGDFCFPHGECLNTDGSFACTCA 906
Query: 1170 HPMVLDASEKRCIRPAESNEQIEETDVYQDLCWEHLSDEYVCSRPLVGKQTTYTECCCLY 1229
RP + D S+E +C + EC C
Sbjct: 907 PGY----------RPGPRGASCLDVD--------ECSEEDLCQSGICTNTDGSFECICPP 948
Query: 1230 GEAWGMQCALCPLKDSDDYAQ----LCNIPVTGRRQPYGRDALVDFSEQYTPEADPYFIQ 1285
G G A C D D+ + LC P + D Y A P
Sbjct: 949 GHRAGPDLASC--LDVDECRERGPALCGSQRC-ENSPGSYRCVRDCDPGY--HAGPEGTC 1003
Query: 1286 DRFLNSFEELQAEECGILNGCENGRCVRVQEGYTCD--CFDGYHLDTAKMTCVDVNECDE 1343
D ++ +E E CG RC Y C C GY T C DV+EC
Sbjct: 1004 DD-VDECQEYGPEICGAQ------RCENTPGSYRCTPACDPGYQ-PTPGGGCQDVDEC-- 1053
Query: 1344 LNNRMSLCKNAKCINTDGSYKCLCLPGYVPSDKPNYCTPLNTALNLE 1390
NR +A C N GS++CLC GY + +C +N L+
Sbjct: 1054 -RNRSFCGAHAVCQNLPGSFQCLCDQGYEGARDGRHCVDVNECETLQ 1099
Score = 153 bits (386), Expect = 1e-36
Identities = 127/463 (27%), Positives = 176/463 (38%), Gaps = 93/463 (20%)
Query: 233 CFQETIGSQ-CGKALPGLSKQEDCCGTVGTSWGFN-KCQKCPKK---------PSYHGY- 280
C+ +T C L ++CC TVG WG + Q+CP P GY
Sbjct: 1183 CYFDTAAPDACDNILARNVTWQECCCTVGEGWGSGCRIQQCPGTETAEYQSLCPHGRGYL 1242
Query: 281 ---------NQMMEC----------------LPGYK---------RVNNTFCQDINEC-Q 305
+ EC PGY C D +EC
Sbjct: 1243 APSGDLSLRRDVDECQLFRDQVCKSGVCVNTAPGYSCYCSNGYYYHTQRLECIDNDECAD 1302
Query: 306 LQGVCPNGECLNTMGSYRCTCKIGFGPDPTFSSCVP-DPPVISEEKGPCYRLVSSGRQCM 364
+ C G C+NT+GSY CTC+ D + CV + + + G C++ V + C
Sbjct: 1303 EEPACEGGRCVNTVGSYHCTCEPPLVLDGSQRRCVSNESQSLDDNLGVCWQEVGADLVCS 1362
Query: 365 HP-LSVHLTKQLCCCSVGKAWGPHCEKCPLPGTAAFKEIC------------PGGMGYTV 411
HP L T CCC G+AWG C CP + F+ +C PGG G
Sbjct: 1363 HPRLDRQATYTECCCLYGEAWGMDCALCPAQDSDDFEALCNVLRPPAYSPPRPGGFGL-- 1420
Query: 412 SGVHRRRPIHHHVGKGPVFVKPKNTQPVAKSTHPPP-LPAKEEPVEALTFSREHGPGVAE 470
P + GP P P +PPP LP P F+R P A
Sbjct: 1421 -------PYEYGPDLGP----PYQGLPYGPELYPPPALPYDPYPPPPGPFARREAPYGA- 1468
Query: 471 PEVATAPPEKEIPSLDQEKTKLEPGQPQLSPGISTIHLHPQFPGIVIEKTSPPVPVEVAP 530
P ++P + + + PG T + + S P P E P
Sbjct: 1469 -------PRFDMPDFEDDGGPYGESEAPAPPGPGTRWPYRSRD----TRRSFPEPEE--P 1515
Query: 531 EASTSSASQVIAPTQVTEINECTVNPDICGAGHCINLPVRYTCICYEGYRFSEQQRKCVD 590
S A + P + E EC + D C G C+ +P +TC C++GYR + CVD
Sbjct: 1516 PEGGSYAGSLAEPYEELEAEECGIL-DGCTNGRCVRVPEGFTCRCFDGYRLDMTRMACVD 1574
Query: 591 IDECTQVQ---HLCSQGRCENTEGSFLCICPAGFMASEEGTNC 630
I+EC + + LC RC NT+GSF CIC GF + + +C
Sbjct: 1575 INECDEAEAASPLCVNARCLNTDGSFRCICRPGFAPTHQPHHC 1617
Score = 151 bits (381), Expect = 5e-36
Identities = 69/130 (53%), Positives = 86/130 (66%), Gaps = 4/130 (3%)
Query: 1255 PVTGRRQPY-GRDALVDFSE-QYTPEADPYFIQDRFLNSFEELQAEECGILNGCENGRCV 1312
P G R PY RD F E + PE Y +EEL+AEECGIL+GC NGRCV
Sbjct: 1492 PGPGTRWPYRSRDTRRSFPEPEEPPEGGSY--AGSLAEPYEELEAEECGILDGCTNGRCV 1549
Query: 1313 RVQEGYTCDCFDGYHLDTAKMTCVDVNECDELNNRMSLCKNAKCINTDGSYKCLCLPGYV 1372
RV EG+TC CFDGY LD +M CVD+NECDE LC NA+C+NTDGS++C+C PG+
Sbjct: 1550 RVPEGFTCRCFDGYRLDMTRMACVDINECDEAEAASPLCVNARCLNTDGSFRCICRPGFA 1609
Query: 1373 PSDKPNYCTP 1382
P+ +P++C P
Sbjct: 1610 PTHQPHHCAP 1619
Score = 110 bits (276), Expect = 7e-24
Identities = 84/308 (27%), Positives = 122/308 (39%), Gaps = 54/308 (17%)
Query: 1131 TYYDPVKLQCFDMDECQDPSSCIDGQCVNTEGSYNCFCTHPMVLDASEKRCIRPAESNEQ 1190
T ++ V C D+DEC C G+C NT G Y C C +LD+S CI S
Sbjct: 346 TGFERVNGSCEDVDECATGGRCQHGECANTRGGYTCVCPDGFLLDSSRSSCI----SQHV 401
Query: 1191 IEETDVYQDLCWEHLSDEYVCSRPLVGKQTTYTECCCLYGEAWGMQCALCPLKDSDDYAQ 1250
I E + C+ L D CS P++ T CC G+AWG C LCP S+ + +
Sbjct: 402 ISEA---KGPCFRVLRDGG-CSLPILRNITKQICCCSRVGKAWGRGCQLCPPFGSEGFRE 457
Query: 1251 LCNI---------PVTGRRQPYGRDA-LVDFSEQYT----------------------PE 1278
+C + +P G++ V S+ T P
Sbjct: 458 ICPAGPGYHYSASDLRYNTRPLGQEPPRVSLSQPRTLPATSRPSAGFLPTHRLEPRPEPR 517
Query: 1279 ADPYFIQDRFLNSFEEL---QAEECGILNG--------CENGRCVRVQEGYTCDCFDGYH 1327
DP + L S + E G +G C GRC+ GYTC C G+
Sbjct: 518 PDPRPGPELPLPSIPAWTGPEIPESGPSSGMCQRNPQVCGPGRCISRPSGYTCACDSGFR 577
Query: 1328 LDTAKMTCVDVNECDELNNRMSLCKNAKCINTDGSYKCLCLPGYVPSDKPNYCTPLNTAL 1387
L C+DV+EC + C +C N+ GS++C+C PG+ + C ++
Sbjct: 578 LSPQGTRCIDVDECRRVPPP---CAPGRCENSPGSFRCVCGPGFRAGPRAAECLDVDECH 634
Query: 1388 NLEKDSDL 1395
+ DL
Sbjct: 635 RVPPPCDL 642
Score = 69.7 bits (169), Expect = 2e-11
Identities = 30/85 (35%), Positives = 44/85 (51%), Gaps = 4/85 (4%)
Query: 754 DIDECQQGNLCVNGQCKNTEGSFRCTCGQGYQLSAAKDQCEDIDECQHRH----LCAHGQ 809
+ +EC + C NG+C F C C GY+L + C DI+EC LC + +
Sbjct: 1533 EAEECGILDGCTNGRCVRVPEGFTCRCFDGYRLDMTRMACVDINECDEAEAASPLCVNAR 1592
Query: 810 CRNTEGSFQCVCDQGYRASGLGDHC 834
C NT+GSF+C+C G+ + HC
Sbjct: 1593 CLNTDGSFRCICRPGFAPTHQPHHC 1617
Score = 66.6 bits (161), Expect = 2e-10
Identities = 31/86 (36%), Positives = 42/86 (48%), Gaps = 4/86 (4%)
Query: 712 LDVDECLEPNVCANGDCSNLEGSYMCSCHKGYTRTPDHKHCRDIDECQQGN----LCVNG 767
L+ +EC + C NG C + + C C GY C DI+EC + LCVN
Sbjct: 1532 LEAEECGILDGCTNGRCVRVPEGFTCRCFDGYRLDMTRMACVDINECDEAEAASPLCVNA 1591
Query: 768 QCKNTEGSFRCTCGQGYQLSAAKDQC 793
+C NT+GSFRC C G+ + C
Sbjct: 1592 RCLNTDGSFRCICRPGFAPTHQPHHC 1617
Score = 63.9 bits (154), Expect = 1e-09
Identities = 28/75 (37%), Positives = 39/75 (52%), Gaps = 4/75 (5%)
Query: 847 CQRGDCINTAGSYDCTCPDGFQLDDNK-TCQDINECEHPGLCGP---QGECLNTEGSFHC 902
C G C+ + C C DG++LD + C DINEC+ P CLNT+GSF C
Sbjct: 1543 CTNGRCVRVPEGFTCRCFDGYRLDMTRMACVDINECDEAEAASPLCVNARCLNTDGSFRC 1602
Query: 903 VCQQGFSISADGRTC 917
+C+ GF+ + C
Sbjct: 1603 ICRPGFAPTHQPHHC 1617
Score = 62.0 bits (149), Expect = 4e-09
Identities = 29/91 (31%), Positives = 50/91 (54%), Gaps = 8/91 (8%)
Query: 1084 PAGESSSEAGGENYKD--ADECLLFGQEICKNGFCLNTRPGYECYCKQGTYYDPVKLQCF 1141
P G S + + E Y++ A+EC + + C NG C+ G+ C C G D ++ C
Sbjct: 1516 PEGGSYAGSLAEPYEELEAEECGIL--DGCTNGRCVRVPEGFTCRCFDGYRLDMTRMACV 1573
Query: 1142 DMDECQDPSS----CIDGQCVNTEGSYNCFC 1168
D++EC + + C++ +C+NT+GS+ C C
Sbjct: 1574 DINECDEAEAASPLCVNARCLNTDGSFRCIC 1604
Score = 57.0 bits (136), Expect = 1e-07
Identities = 33/91 (36%), Positives = 43/91 (47%), Gaps = 4/91 (4%)
Query: 781 GQGYQLSAAKDQCE-DIDECQHRHLCAHGQCRNTEGSFQCVCDQGYRASGLGDHCEDINE 839
G Y S A+ E + +EC C +G+C F C C GYR C DINE
Sbjct: 1518 GGSYAGSLAEPYEELEAEECGILDGCTNGRCVRVPEGFTCRCFDGYRLDMTRMACVDINE 1577
Query: 840 CLEDKS---VCQRGDCINTAGSYDCTCPDGF 867
C E ++ +C C+NT GS+ C C GF
Sbjct: 1578 CDEAEAASPLCVNARCLNTDGSFRCICRPGF 1608
Score = 55.8 bits (133), Expect = 3e-07
Identities = 27/79 (34%), Positives = 36/79 (45%), Gaps = 10/79 (12%)
Query: 913 DGRTCEDIDECVNNTVCDSHGFCDNTAGSFRCLCYQGFQAPQDGQGCVDVNEC---ELLS 969
+ C +D C N G C F C C+ G++ CVD+NEC E S
Sbjct: 1533 EAEECGILDGCTN-------GRCVRVPEGFTCRCFDGYRLDMTRMACVDINECDEAEAAS 1585
Query: 970 GVCGEAFCENVEGSFLCVC 988
+C A C N +GSF C+C
Sbjct: 1586 PLCVNARCLNTDGSFRCIC 1604
Score = 52.0 bits (123), Expect = 4e-06
Identities = 26/64 (40%), Positives = 31/64 (48%), Gaps = 5/64 (7%)
Query: 286 CLPGYKR-VNNTFCQDINECQ----LQGVCPNGECLNTMGSYRCTCKIGFGPDPTFSSCV 340
C GY+ + C DINEC +C N CLNT GS+RC C+ GF P C
Sbjct: 1559 CFDGYRLDMTRMACVDINECDEAEAASPLCVNARCLNTDGSFRCICRPGFAPTHQPHHCA 1618
Query: 341 PDPP 344
P P
Sbjct: 1619 PARP 1622
Score = 50.8 bits (120), Expect = 9e-06
Identities = 28/79 (35%), Positives = 40/79 (50%), Gaps = 7/79 (8%)
Query: 631 IDVDECLRPDVCGEGHCVNTVGAFRCEYCDSGYRMTQ-RGRCEDIDECLNPST----CPD 685
++ +EC D C G CV F C C GYR+ R C DI+EC C +
Sbjct: 1532 LEAEECGILDGCTNGRCVRVPEGFTCR-CFDGYRLDMTRMACVDINECDEAEAASPLCVN 1590
Query: 686 EQCVNSPGSYQCVPCTEGF 704
+C+N+ GS++C+ C GF
Sbjct: 1591 ARCLNTDGSFRCI-CRPGF 1608
Score = 48.5 bits (114), Expect = 4e-05
Identities = 36/134 (26%), Positives = 55/134 (41%), Gaps = 28/134 (20%)
Query: 1211 CSRPLVGKQTTYTECCCLYGEAWGMQ-CALCPLKDSDDYAQLCNIPVTGRRQPYGRDALV 1269
C+ PL G +T CC G AWG+ C LC + G V
Sbjct: 298 CASPLPGLRTQEV-CCRGAGLAWGVHDCQLCS-------------------ERLGNSERV 337
Query: 1270 DFSEQYTPEADPYFIQDRFLNSFEELQAEECGILNGCENGRCVRVQEGYTCDCFDGYHLD 1329
+ P +R S E++ +EC C++G C + GYTC C DG+ LD
Sbjct: 338 SAPDGPCPTGF-----ERVNGSCEDV--DECATGGRCQHGECANTRGGYTCVCPDGFLLD 390
Query: 1330 TAKMTCVDVNECDE 1343
+++ +C+ + E
Sbjct: 391 SSRSSCISQHVISE 404
Score = 48.5 bits (114), Expect = 4e-05
Identities = 29/107 (27%), Positives = 46/107 (42%), Gaps = 12/107 (11%)
Query: 857 GSYDCTCPDGFQLDDNKTCQDINECEHPGLCGPQGECLNTEGSFHCVCQQGFSISADGRT 916
GSY + + ++ + + C ++ C + G C+ F C C G+ +
Sbjct: 1519 GSYAGSLAEPYEELEAEECGILDGCTN-------GRCVRVPEGFTCRCFDGYRLDMTRMA 1571
Query: 917 CEDIDEC----VNNTVCDSHGFCDNTAGSFRCLCYQGFQAPQDGQGC 959
C DI+EC + +C + C NT GSFRC+C GF C
Sbjct: 1572 CVDINECDEAEAASPLC-VNARCLNTDGSFRCICRPGFAPTHQPHHC 1617
>gi|18497288 latent transforming growth factor beta binding protein 3
isoform 2 [Homo sapiens]
Length = 1256
Score = 832 bits (2148), Expect = 0.0
Identities = 482/1265 (38%), Positives = 636/1265 (50%), Gaps = 209/1265 (16%)
Query: 25 RIKVVFTPSICKVTCTKGSCQNSCEKGNTTTLISENGHAADTLTATNFRVVICHLPCMNG 84
R KVVF P ICK TC KG C++SC++G+ TLI ENGH+ DTLT + FRVV+C LPCMNG
Sbjct: 61 RFKVVFAPVICKRTCLKGQCRDSCQQGSNMTLIGENGHSTDTLTGSGFRVVVCPLPCMNG 120
Query: 85 GQCSSRDKCQCPPNFTGKLCQIPVHGA--------------------SVPKLYQHSQQ-- 122
GQCSSR++C CPP+FTG+ CQ+P GA ++P L
Sbjct: 121 GQCSSRNQCLCPPDFTGRFCQVPAGGAGGGTGGSGPGLSRTGALSTGALPPLAPEGDSVA 180
Query: 123 --------------PGKALGTHVIHSTHTLPLTVTSQQGVKVKFPPNIVNIHVKHPPEAS 168
PG G H+ +PL Q +V+ PP +VN+ V HPPEAS
Sbjct: 181 SKHAIYAVQVIADPPGPGEGPPAQHAAFLVPLG-PGQISAEVQAPPPVVNVRVHHPPEAS 239
Query: 169 VQIHQVSRIDGPTGQKTKEAQPGQSQVSYQGLPVQKTQTIHSTYSHQQVIPHVYPVAAKT 228
VQ+H++ + + ++ P + S+ P QK
Sbjct: 240 VQVHRIESSNAESAAPSQHLLP-HPKPSHPRPPTQKP----------------------- 275
Query: 229 QLGRCFQETIGSQ-CGK-ALPGLSKQEDCCGTVGTSWGFNKCQKCPK-------KPSYHG 279
LGRCFQ+T+ Q CG LPGL+KQEDCCG++GT+WG +KC KCP+ KP
Sbjct: 276 -LGRCFQDTLPKQPCGSNPLPGLTKQEDCCGSIGTAWGQSKCHKCPQLQYTGVQKPGPVR 334
Query: 280 YNQMMECLPGYKRVNNTFCQDINECQLQGVCPNGECLNTMGSYRCTCKIGFGPDPTFSSC 339
+C GYKR+N+T CQDINEC + GVC +G+CLN GSYRC C G P+ + C
Sbjct: 335 GEVGADCPQGYKRLNSTHCQDINECAMPGVCRHGDCLNNPGSYRCVCPPGHSLGPSRTQC 394
Query: 340 VPDPPVISEEKGPCYRLVSSGRQCMHPLSVHLTKQLCCCSVGKAWGPHCEKCPLPGTAAF 399
+ D P EEK C+RLVS QC HPL+ LT+QLCCCSVGKAWG C++CP GTAAF
Sbjct: 395 IADKP---EEKSLCFRLVSPEHQCQHPLTTRLTRQLCCCSVGKAWGARCQRCPTDGTAAF 451
Query: 400 KEICPGGMGYTVSGVHRRRPIHHHVG-------KGPVFVKPKNTQ-PVAKSTHPPPLPAK 451
KEICP G GY + H+ I GP PK Q P + S PPP +
Sbjct: 452 KEICPAGKGYHILTSHQTLTIQGESDFSLFLHPDGP----PKPQQLPESPSQAPPPEDTE 507
Query: 452 EEPVEALTFSREHGPGVAEPEVATAPPEKEIPSLDQEKTKLEPGQPQLSPGISTIHLHPQ 511
EE V T P E S+ Q P +T P
Sbjct: 508 EER-----------------GVTTDSPVSEERSVQQSH-----------PTATTTPARP- 538
Query: 512 FPGIVIEKTSPPVPVEVAPEASTSSASQVIAPTQVTEINECTVNPDICGAGHCINLPVRY 571
+P + I + SPP P+ S ++ IAPTQVTE +EC +N +ICG G C+ P Y
Sbjct: 539 YPEL-ISRPSPPTMRWFLPDLPPSRSAVEIAPTQVTETDECRLNQNICGHGECVPGPPDY 597
Query: 572 TCICYEGYRFSEQQRKCVDIDECTQVQHLCSQGRCENTEGSFLCICPAGFM--ASEEGTN 629
+C C GYR Q R CVD++EC +G C NT GS+ C C G+ G +
Sbjct: 598 SCHCNPGYRSHPQHRYCVDVNECEAEPCGPGRGICMNTGGSYNCHCNRGYRLHVGAGGRS 657
Query: 630 CIDVDECLRPDVCGEG-HCVNTVGAFRCEYCDSGYRM--TQRGRCEDIDECLNPSTCPDE 686
C+D++EC +P +CG+G C+N G ++C C GYR+ ++ CEDIDEC +PS+CPD
Sbjct: 658 CVDLNECAKPHLCGDGGFCINFPGHYKCN-CYPGYRLKASRPPVCEDIDECRDPSSCPDG 716
Query: 687 QCVNSPGSYQCVPCTEGFRGWNG-QCLDVDECLEPNVCANGDCSNLEGSYMCSCHKGYTR 745
+C N PGS++C+ C G+R G C DV+EC E + C+ G C NL GS+ C+C +GY
Sbjct: 717 KCENKPGSFKCIACQPGYRSQGGGACRDVNECAEGSPCSPGWCENLPGSFRCTCAQGYAP 776
Query: 746 TPDHKHCRDIDECQQGNLCVNGQCKNTEGSFRCTCGQGYQLSAAKDQCEDIDECQHRHLC 805
PD + C D+DEC+ G++C NG C NT GSF+C C GY LS + CEDIDEC C
Sbjct: 777 APDGRSCLDVDECEAGDVCDNGICSNTPGSFQCQCLSGYHLSRDRSHCEDIDECDFPAAC 836
Query: 806 AHGQCRNTEGSFQCVCDQGYRASGLGDHCEDINECLEDKSVC-QRGDCINTAGSYDCTCP 864
G C NT GS++C+C QG+R G G C+DI+EC +D S+C G C N GSY C C
Sbjct: 837 IGGDCINTNGSYRCLCPQGHRLVG-GRKCQDIDECSQDPSLCLPHGACKNLQGSYVCVCD 895
Query: 865 DGF-QLDDNKTCQDINECEHPGLC-----------------GPQGECLNTEGS------- 899
+GF D C+++ + H C Q EC + G+
Sbjct: 896 EGFTPTQDQHGCEEVEQPHHKKECYLNFDDTVFCDSVLATNVTQQECCCSLGAGWGDHCE 955
Query: 900 -----------FHCVCQQGFSISADGRTC-------EDIDECV--NNTVCDSHGFCDNTA 939
FH +C G + D DIDEC+ + +C G C NT
Sbjct: 956 IYPCPVYSSAEFHSLCPDGKGYTQDNNIVNYGIPAHRDIDECMLFGSEIC-KEGKCVNTQ 1014
Query: 940 GSFRCLCYQGFQAPQDGQGCVDVNECELLSGVCGEAFCENVEGSFLCVCADENQEYSPMT 999
+ C C QGF + CVDV+EC L C CEN G + C C EYSP
Sbjct: 1015 PGYECYCKQGFYYDGNLLECVDVDEC-LDESNCRNGVCENTRGGYRCACTPP-AEYSPAQ 1072
Query: 1000 GQCRSRTSTDLDVDVDQPKEEKKECYYNLNDASLCDNVLA-PNVTKQECCCTSGAGWGDN 1058
QC S ++++ E + C+ + +C LA P +T +CCC G GWG
Sbjct: 1073 RQCLS------PEEMERAPERRDVCWSQRGEDGMCAGPLAGPALTFDDCCCRQGRGWGAQ 1126
Query: 1059 CEIFPCPVLGTA-----------EFTEMCPKGKGFVPAGESSSEAGGENYKDADECLLFG 1107
C PCP G F + P G P E SSE +D+DEC
Sbjct: 1127 CR--PCPPRGAGSHCPTSQSESNSFWDTSPLLLGKPPRDEDSSE------EDSDECR--- 1175
Query: 1108 QEICKNGFCLNTRPGYECYCKQGTYYDPVKLQCFDMDECQDPSS----CIDGQCVNTEGS 1163
C +G C+ G C C G D + +C D+DEC++ + C +CVNT GS
Sbjct: 1176 ---CVSGRCVPRPGGAVCECPGGFQLDASRARCVDIDECRELNQRGLLCKSERCVNTSGS 1232
Query: 1164 YNCFC 1168
+ C C
Sbjct: 1233 FRCVC 1237
Score = 563 bits (1451), Expect = e-160
Identities = 297/723 (41%), Positives = 405/723 (56%), Gaps = 57/723 (7%)
Query: 673 DIDEC-LNPSTCPDEQCVNSPGSYQCVPCTEGFRGW--NGQCLDVDEC-LEPNVCANGDC 728
+ DEC LN + C +CV P Y C C G+R + C+DV+EC EP G C
Sbjct: 574 ETDECRLNQNICGHGECVPGPPDYSC-HCNPGYRSHPQHRYCVDVNECEAEPCGPGRGIC 632
Query: 729 SNLEGSYMCSCHKGYTRT--PDHKHCRDIDECQQGNLCVNGQ-CKNTEGSFRCTCGQGYQ 785
N GSY C C++GY + C D++EC + +LC +G C N G ++C C GY+
Sbjct: 633 MNTGGSYNCHCNRGYRLHVGAGGRSCVDLNECAKPHLCGDGGFCINFPGHYKCNCYPGYR 692
Query: 786 LSAAKDQ-CEDIDECQHRHLCAHGQCRNTEGSFQCV-CDQGYRASGLGDHCEDINECLED 843
L A++ CEDIDEC+ C G+C N GSF+C+ C GYR+ G G C D+NEC E
Sbjct: 693 LKASRPPVCEDIDECRDPSSCPDGKCENKPGSFKCIACQPGYRSQG-GGACRDVNECAEG 751
Query: 844 KSVCQRGDCINTAGSYDCTCPDGFQ-LDDNKTCQDINECEHPGLCGPQGECLNTEGSFHC 902
S C G C N GS+ CTC G+ D ++C D++ECE +C G C NT GSF C
Sbjct: 752 -SPCSPGWCENLPGSFRCTCAQGYAPAPDGRSCLDVDECEAGDVCD-NGICSNTPGSFQC 809
Query: 903 VCQQGFSISADGRTCEDIDECVNNTVCDSHGFCDNTAGSFRCLCYQGFQAPQDGQGCVDV 962
C G+ +S D CEDIDEC C G C NT GS+RCLC QG + G+ C D+
Sbjct: 810 QCLSGYHLSRDRSHCEDIDECDFPAACIG-GDCINTNGSYRCLCPQGHRLV-GGRKCQDI 867
Query: 963 NECELLSGVC-GEAFCENVEGSFLCVCADENQEYSPMTGQCRSRTSTDLDVDVDQPKEEK 1021
+EC +C C+N++GS++CVC ++ ++P Q +V+QP K
Sbjct: 868 DECSQDPSLCLPHGACKNLQGSYVCVC---DEGFTPTQDQHGCE-------EVEQP-HHK 916
Query: 1022 KECYYNLNDASLCDNVLAPNVTKQECCCTSGAGWGDNCEIFPCPVLGTAEFTEMCPKGKG 1081
KECY N +D CD+VLA NVT+QECCC+ GAGWGD+CEI+PCPV +AEF +CP GKG
Sbjct: 917 KECYLNFDDTVFCDSVLATNVTQQECCCSLGAGWGDHCEIYPCPVYSSAEFHSLCPDGKG 976
Query: 1082 FVPAGESSSEAGGENYKDADECLLFGQEICKNGFCLNTRPGYECYCKQGTYYDPVKLQCF 1141
+ + G ++D DEC+LFG EICK G C+NT+PGYECYCKQG YYD L+C
Sbjct: 977 YTQ-DNNIVNYGIPAHRDIDECMLFGSEICKEGKCVNTQPGYECYCKQGFYYDGNLLECV 1035
Query: 1142 DMDECQDPSSCIDGQCVNTEGSYNCFCTHPMVLDASEKRCIRPAESNEQIEETDVYQDLC 1201
D+DEC D S+C +G C NT G Y C CT P ++++C+ P E++E +D+C
Sbjct: 1036 DVDECLDESNCRNGVCENTRGGYRCACTPPAEYSPAQRQCLSP----EEMERAPERRDVC 1091
Query: 1202 WEHLSDEYVCSRPLVGKQTTYTECCCLYGEAWGMQCALCPLKDSDDYAQLCNIPVTGRRQ 1261
W ++ +C+ PL G T+ +CCC G WG QC CP + + G
Sbjct: 1092 WSQRGEDGMCAGPLAGPALTFDDCCCRQGRGWGAQCRPCPPRGA------------GSHC 1139
Query: 1262 PYGRDALVDFSEQYTPEADPYFI--QDRFLNSFEELQAEECGILNGCENGRCVRVQEGYT 1319
P + F + P + R +S EE ++EC C +GRCV G
Sbjct: 1140 PTSQSESNSFWD-----TSPLLLGKPPRDEDSSEE-DSDECR----CVSGRCVPRPGGAV 1189
Query: 1320 CDCFDGYHLDTAKMTCVDVNECDELNNRMSLCKNAKCINTDGSYKCLCLPGYVPSDKPNY 1379
C+C G+ LD ++ CVD++EC ELN R LCK+ +C+NT GS++C+C G+ S
Sbjct: 1190 CECPGGFQLDASRARCVDIDECRELNQRGLLCKSERCVNTSGSFRCVCKAGFARSRPHGA 1249
Query: 1380 CTP 1382
C P
Sbjct: 1250 CVP 1252
Score = 180 bits (457), Expect = 7e-45
Identities = 152/575 (26%), Positives = 224/575 (38%), Gaps = 128/575 (22%)
Query: 836 DINECLEDKSVCQRGDCINTAGSYDCTCPDGFQLD-DNKTCQDINECEHPGLCGP-QGEC 893
+ +EC ++++C G+C+ Y C C G++ ++ C D+NECE CGP +G C
Sbjct: 574 ETDECRLNQNICGHGECVPGPPDYSCHCNPGYRSHPQHRYCVDVNECEAEP-CGPGRGIC 632
Query: 894 LNTEGSFHCVCQQGFS--ISADGRTCEDIDECVNNTVCDSHGFCDNTAGSFRCLCYQGFQ 951
+NT GS++C C +G+ + A GR+C D++EC +C GFC N G ++C CY G++
Sbjct: 633 MNTGGSYNCHCNRGYRLHVGAGGRSCVDLNECAKPHLCGDGGFCINFPGHYKCNCYPGYR 692
Query: 952 APQDGQG-CVDVNECELLSGVCGEAFCENVEGSFLCVCADENQEYSPMTGQCRSRTSTDL 1010
C D++EC S C + CEN GSF C+ S G CR
Sbjct: 693 LKASRPPVCEDIDECRDPSS-CPDGKCENKPGSFKCIACQPGYR-SQGGGACR------- 743
Query: 1011 DVDVDQPKEEKKECYYNLNDASLCDNVLAPNVTKQECCCTSGAGWGDNCEIFPCPVLGTA 1070
+ EC + S C GW CE P
Sbjct: 744 ---------DVNECA----EGSPCS-----------------PGW---CENLPGSF---- 766
Query: 1071 EFTEMCPKGKGFVPAGESSSEAGGENYKDADECLLFGQEICKNGFCLNTRPGYECYCKQG 1130
C +G+ PA + G + D DEC ++C NG C NT ++C C G
Sbjct: 767 ----RCTCAQGYAPAPD------GRSCLDVDECE--AGDVCDNGICSNTPGSFQCQCLSG 814
Query: 1131 TYYDPVKLQCFDMDECQDPSSCIDGQCVNTEGSYNCFCTHPMVLDASEKRCIRPAESNEQ 1190
+ + C D+DEC P++CI G C+NT GSY C C L K C +
Sbjct: 815 YHLSRDRSHCEDIDECDFPAACIGGDCINTNGSYRCLCPQGHRLVGGRK-C-------QD 866
Query: 1191 IEETDVYQDLCWEHLSDEYVCSRPLVGKQTTYTECCCLYGEAWGMQCALCPLKDSDDYAQ 1250
I+E LC H + + + Q +Y C C G P +D +
Sbjct: 867 IDECSQDPSLCLPHGACKNL--------QGSYV-CVCDEG--------FTPTQDQHGCEE 909
Query: 1251 LCNIPVTGRRQPYGRDALVDFSEQYTPEADPYFIQDRFLNSFEELQAEECGILNGCENGR 1310
+ QP+ + E Y D F + Q E C L
Sbjct: 910 V--------EQPHHK------KECYLNFDDTVFCDSVLATNVT--QQECCCSLGAGWGDH 953
Query: 1311 CVRVQEGYTCDCFD------------GYHLDTAKMTCV-----DVNECDELNNRMSLCKN 1353
C E Y C + GY D + D++EC + +CK
Sbjct: 954 C----EIYPCPVYSSAEFHSLCPDGKGYTQDNNIVNYGIPAHRDIDECMLFGSE--ICKE 1007
Query: 1354 AKCINTDGSYKCLCLPGYVPSDKPNYCTPLNTALN 1388
KC+NT Y+C C G+ C ++ L+
Sbjct: 1008 GKCVNTQPGYECYCKQGFYYDGNLLECVDVDECLD 1042
Score = 86.3 bits (212), Expect = 2e-16
Identities = 64/230 (27%), Positives = 90/230 (39%), Gaps = 54/230 (23%)
Query: 1024 CYYNLNDASLCDNVLAPNVTKQECCCTS-GAGWGDNCEIFPCPVLGTAEFTEMCPKGKGF 1082
C+ + C + P +TKQE CC S G WG + + CP L ++T G
Sbjct: 279 CFQDTLPKQPCGSNPLPGLTKQEDCCGSIGTAWGQS-KCHKCPQL---QYT-------GV 327
Query: 1083 VPAGESSSEAGGENYKDADECLLFGQEICKNGFCLNTRPGYECYCKQGTYYDPVKLQCFD 1142
G E G + C QG Y C D
Sbjct: 328 QKPGPVRGEVGAD-------------------------------CPQG-YKRLNSTHCQD 355
Query: 1143 MDECQDPSSCIDGQCVNTEGSYNCFCTHPMVLDASEKRCIRPAESNEQIEETDVYQDLCW 1202
++EC P C G C+N GSY C C L S +CI A+ E+ + LC+
Sbjct: 356 INECAMPGVCRHGDCLNNPGSYRCVCPPGHSLGPSRTQCI--ADKPEE-------KSLCF 406
Query: 1203 EHLSDEYVCSRPLVGKQTTYTECCCLYGEAWGMQCALCPLKDSDDYAQLC 1252
+S E+ C PL + T CCC G+AWG +C CP + + ++C
Sbjct: 407 RLVSPEHQCQHPLTTRLTRQL-CCCSVGKAWGARCQRCPTDGTAAFKEIC 455
Score = 67.8 bits (164), Expect = 7e-11
Identities = 30/76 (39%), Positives = 40/76 (52%), Gaps = 3/76 (3%)
Query: 559 CGAGHCINLPVRYTCICYEGYRFSEQQRKCVDIDECTQVQH---LCSQGRCENTEGSFLC 615
C +G C+ P C C G++ + +CVDIDEC ++ LC RC NT GSF C
Sbjct: 1176 CVSGRCVPRPGGAVCECPGGFQLDASRARCVDIDECRELNQRGLLCKSERCVNTSGSFRC 1235
Query: 616 ICPAGFMASEEGTNCI 631
+C AGF S C+
Sbjct: 1236 VCKAGFARSRPHGACV 1251
Score = 62.4 bits (150), Expect = 3e-09
Identities = 34/87 (39%), Positives = 41/87 (47%), Gaps = 11/87 (12%)
Query: 590 DIDECTQVQHLCSQGRCENTEGSFLCICPAGFMASEEGTNCIDVDECL----RPDVCGEG 645
D DEC C GRC G +C CP GF C+D+DEC R +C
Sbjct: 1170 DSDECR-----CVSGRCVPRPGGAVCECPGGFQLDASRARCVDIDECRELNQRGLLCKSE 1224
Query: 646 HCVNTVGAFRCEYCDSGY-RMTQRGRC 671
CVNT G+FRC C +G+ R G C
Sbjct: 1225 RCVNTSGSFRC-VCKAGFARSRPHGAC 1250
Score = 48.1 bits (113), Expect = 6e-05
Identities = 26/77 (33%), Positives = 38/77 (49%), Gaps = 9/77 (11%)
Query: 270 KCPKKPSYHGYNQMMECLPGYKR-VNNTFCQDINEC----QLQGVCPNGECLNTMGSYRC 324
+C +P + EC G++ + C DI+EC Q +C + C+NT GS+RC
Sbjct: 1180 RCVPRPG----GAVCECPGGFQLDASRARCVDIDECRELNQRGLLCKSERCVNTSGSFRC 1235
Query: 325 TCKIGFGPDPTFSSCVP 341
CK GF +CVP
Sbjct: 1236 VCKAGFARSRPHGACVP 1252
Score = 42.4 bits (98), Expect = 0.003
Identities = 20/52 (38%), Positives = 30/52 (57%), Gaps = 7/52 (13%)
Query: 1321 DCFDGY-HLDTAKMTCVDVNECDELNNRMSLCKNAKCINTDGSYKCLCLPGY 1371
DC GY L++ C D+NEC +C++ C+N GSY+C+C PG+
Sbjct: 340 DCPQGYKRLNSTH--CQDINECA----MPGVCRHGDCLNNPGSYRCVCPPGH 385
Score = 39.7 bits (91), Expect = 0.020
Identities = 35/140 (25%), Positives = 53/140 (37%), Gaps = 27/140 (19%)
Query: 1201 CWEHLSDEYVC-SRPLVGKQTTYTECCCLYGEAWGM-QCALCPLKDSDDYAQLCNIPVTG 1258
C++ + C S PL G T +CC G AWG +C CP + TG
Sbjct: 279 CFQDTLPKQPCGSNPLPGL-TKQEDCCGSIGTAWGQSKCHKCP-----------QLQYTG 326
Query: 1259 RRQP--YGRDALVDFSEQYTPEADPYFIQDRFLNSFEELQAEECGILNGCENGRCVRVQE 1316
++P + D + Y + LNS EC + C +G C+
Sbjct: 327 VQKPGPVRGEVGADCPQGY-----------KRLNSTHCQDINECAMPGVCRHGDCLNNPG 375
Query: 1317 GYTCDCFDGYHLDTAKMTCV 1336
Y C C G+ L ++ C+
Sbjct: 376 SYRCVCPPGHSLGPSRTQCI 395
Score = 37.7 bits (86), Expect = 0.078
Identities = 15/47 (31%), Positives = 22/47 (46%)
Query: 1338 VNECDELNNRMSLCKNAKCINTDGSYKCLCLPGYVPSDKPNYCTPLN 1384
V E DE ++C + +C+ Y C C PGY + YC +N
Sbjct: 572 VTETDECRLNQNICGHGECVPGPPDYSCHCNPGYRSHPQHRYCVDVN 618
>gi|194328809 latent transforming growth factor beta binding protein 3
isoform 1 [Homo sapiens]
Length = 1303
Score = 820 bits (2119), Expect = 0.0
Identities = 484/1306 (37%), Positives = 637/1306 (48%), Gaps = 244/1306 (18%)
Query: 25 RIKVVFTPSICKVTCTKGSCQNSCEKGNTTTLISENGHAADTLTATNFRVVICHLPCMNG 84
R KVVF P ICK TC KG C++SC++G+ TLI ENGH+ DTLT + FRVV+C LPCMNG
Sbjct: 61 RFKVVFAPVICKRTCLKGQCRDSCQQGSNMTLIGENGHSTDTLTGSGFRVVVCPLPCMNG 120
Query: 85 GQCSSRDKCQCPPNFTGKLCQIPVHGA--------------------SVPKLYQHSQQ-- 122
GQCSSR++C CPP+FTG+ CQ+P GA ++P L
Sbjct: 121 GQCSSRNQCLCPPDFTGRFCQVPAGGAGGGTGGSGPGLSRTGALSTGALPPLAPEGDSVA 180
Query: 123 --------------PGKALGTHVIHSTHTLPLTVTSQQGVKVKFPPNIVNIHVKHPPEAS 168
PG G H+ +PL Q +V+ PP +VN+ V HPPEAS
Sbjct: 181 SKHAIYAVQVIADPPGPGEGPPAQHAAFLVPLG-PGQISAEVQAPPPVVNVRVHHPPEAS 239
Query: 169 VQIHQVSRIDGPTGQKTKEAQPGQSQVSYQGLPVQKTQTIHSTYSHQQVIPHVYPVAAKT 228
VQ+H++ + + ++ P + S+ P QK
Sbjct: 240 VQVHRIESSNAESAAPSQHLLP-HPKPSHPRPPTQKP----------------------- 275
Query: 229 QLGRCFQETIGSQ-CGK-ALPGLSKQEDCCGTVGTSWGFNKCQKCPK-------KPSYHG 279
LGRCFQ+T+ Q CG LPGL+KQEDCCG++GT+WG +KC KCP+ KP
Sbjct: 276 -LGRCFQDTLPKQPCGSNPLPGLTKQEDCCGSIGTAWGQSKCHKCPQLQYTGVQKPGPVR 334
Query: 280 YNQMMECLPGYKRVNNTFCQDINECQLQGVCPNGECLNTMGSYRCTCKIGFGPDPTFSSC 339
+C GYKR+N+T CQDINEC + GVC +G+CLN GSYRC C G P+ + C
Sbjct: 335 GEVGADCPQGYKRLNSTHCQDINECAMPGVCRHGDCLNNPGSYRCVCPPGHSLGPSRTQC 394
Query: 340 VPDPPVISEEKGPCYRLVSSGRQCMHPLSVHLTKQLCCCSVGKAWGPHCEKCPLPGTAAF 399
+ D P EEK C+RLVS QC HPL+ LT+QLCCCSVGKAWG C++CP GTAAF
Sbjct: 395 IADKP---EEKSLCFRLVSPEHQCQHPLTTRLTRQLCCCSVGKAWGARCQRCPTDGTAAF 451
Query: 400 KEICPGGMGYTVSGVHRRRPIHHHVG-------KGPVFVKPKNTQ-PVAKSTHPPPLPAK 451
KEICP G GY + H+ I GP PK Q P + S PPP +
Sbjct: 452 KEICPAGKGYHILTSHQTLTIQGESDFSLFLHPDGP----PKPQQLPESPSQAPPPEDTE 507
Query: 452 EEPVEALTFSREHGPGVAEPEVATAPPEKEIPSLDQEKTKLEPGQPQLSPGISTIHLHPQ 511
EE V T P E S+ Q P +T P
Sbjct: 508 EER-----------------GVTTDSPVSEERSVQQSH-----------PTATTTPARP- 538
Query: 512 FPGIVIEKTSPPVPVEVAPEASTSSASQVIAPTQVTEINECTVNPDICGAGHCINLPVRY 571
+P + I + SPP P+ S ++ IAPTQVTE +EC +N +ICG G C+ P Y
Sbjct: 539 YPEL-ISRPSPPTMRWFLPDLPPSRSAVEIAPTQVTETDECRLNQNICGHGECVPGPPDY 597
Query: 572 TCICYEGYRFSEQQRKCVDIDECTQVQHLCSQGRCENTEGSFLCICPAGFM--ASEEGTN 629
+C C GYR Q R CVD++EC +G C NT GS+ C C G+ G +
Sbjct: 598 SCHCNPGYRSHPQHRYCVDVNECEAEPCGPGRGICMNTGGSYNCHCNRGYRLHVGAGGRS 657
Query: 630 CIDVDECLRPDVCGEG-HCVNTVGAFRCEYCDSGYRM--TQRGRCEDIDECLNPSTCPDE 686
C+D++EC +P +CG+G C+N G ++C C GYR+ ++ CEDIDEC +PS+CPD
Sbjct: 658 CVDLNECAKPHLCGDGGFCINFPGHYKCN-CYPGYRLKASRPPVCEDIDECRDPSSCPDG 716
Query: 687 QCVNSPGSYQCVPCTEGFRGWNG-QCLDVDECLEPNVCANGDCSNLEGSYMCSCHKGYTR 745
+C N PGS++C+ C G+R G C DV+EC E + C+ G C NL GS+ C+C +GY
Sbjct: 717 KCENKPGSFKCIACQPGYRSQGGGACRDVNECAEGSPCSPGWCENLPGSFRCTCAQGYAP 776
Query: 746 TPDHKHCRDIDECQQGNLCVNGQCKNTEGSFRCTCGQGYQLSAAKDQCEDIDECQHRHLC 805
PD + C D+DEC+ G++C NG C NT GSF+C C GY LS + CEDIDEC C
Sbjct: 777 APDGRSCLDVDECEAGDVCDNGICSNTPGSFQCQCLSGYHLSRDRSHCEDIDECDFPAAC 836
Query: 806 AHGQCRNTEGSFQCVCDQGYRASGLGDHCEDINECLEDKSVC-QRGDCINTAGSYDCTCP 864
G C NT GS++C+C QG+R G G C+DI+EC +D S+C G C N GSY C C
Sbjct: 837 IGGDCINTNGSYRCLCPQGHRLVG-GRKCQDIDECSQDPSLCLPHGACKNLQGSYVCVCD 895
Query: 865 DGF-QLDDNKTCQDINECEHPGLC-----------------GPQGECLNTEGS------- 899
+GF D C+++ + H C Q EC + G+
Sbjct: 896 EGFTPTQDQHGCEEVEQPHHKKECYLNFDDTVFCDSVLATNVTQQECCCSLGAGWGDHCE 955
Query: 900 -----------FHCVCQQGFSISADGRTC-------EDIDECV--NNTVCDSHGFCDNTA 939
FH +C G + D DIDEC+ + +C G C NT
Sbjct: 956 IYPCPVYSSAEFHSLCPDGKGYTQDNNIVNYGIPAHRDIDECMLFGSEIC-KEGKCVNTQ 1014
Query: 940 GSFRCLCYQGFQAPQDGQGCVDVNECELLSGVCGEAFCENVEGSFLCVCADENQEYSPMT 999
+ C C QGF + CVDV+EC L C CEN G + C C EYSP
Sbjct: 1015 PGYECYCKQGFYYDGNLLECVDVDEC-LDESNCRNGVCENTRGGYRCACTPP-AEYSPAQ 1072
Query: 1000 GQCRSRTSTDLD-----------------------------------------VDVDQPK 1018
QC S D+D ++
Sbjct: 1073 RQCLSPEEMDVDECQDPAACRPGRCVNLPGSYRCECRPPWVPGPSGRDCQLPESPAERAP 1132
Query: 1019 EEKKECYYNLNDASLCDNVLA-PNVTKQECCCTSGAGWGDNCEIFPCPVLGTA------- 1070
E + C+ + +C LA P +T +CCC G GWG C PCP G
Sbjct: 1133 ERRDVCWSQRGEDGMCAGPLAGPALTFDDCCCRQGRGWGAQCR--PCPPRGAGSHCPTSQ 1190
Query: 1071 ----EFTEMCPKGKGFVPAGESSSEAGGENYKDADECLLFGQEICKNGFCLNTRPGYECY 1126
F + P G P E SSE +D+DEC C +G C+ G C
Sbjct: 1191 SESNSFWDTSPLLLGKPPRDEDSSE------EDSDECR------CVSGRCVPRPGGAVCE 1238
Query: 1127 CKQGTYYDPVKLQCFDMDECQDPSS----CIDGQCVNTEGSYNCFC 1168
C G D + +C D+DEC++ + C +CVNT GS+ C C
Sbjct: 1239 CPGGFQLDASRARCVDIDECRELNQRGLLCKSERCVNTSGSFRCVC 1284
Score = 546 bits (1406), Expect = e-155
Identities = 297/766 (38%), Positives = 404/766 (52%), Gaps = 96/766 (12%)
Query: 673 DIDEC-LNPSTCPDEQCVNSPGSYQCVPCTEGFRGW--NGQCLDVDEC-LEPNVCANGDC 728
+ DEC LN + C +CV P Y C C G+R + C+DV+EC EP G C
Sbjct: 574 ETDECRLNQNICGHGECVPGPPDYSC-HCNPGYRSHPQHRYCVDVNECEAEPCGPGRGIC 632
Query: 729 SNLEGSYMCSCHKGYTRT--PDHKHCRDIDECQQGNLCVNGQ-CKNTEGSFRCTCGQGYQ 785
N GSY C C++GY + C D++EC + +LC +G C N G ++C C GY+
Sbjct: 633 MNTGGSYNCHCNRGYRLHVGAGGRSCVDLNECAKPHLCGDGGFCINFPGHYKCNCYPGYR 692
Query: 786 LSAAKDQ-CEDIDECQHRHLCAHGQCRNTEGSFQCV-CDQGYRASGLGDHCEDINECLED 843
L A++ CEDIDEC+ C G+C N GSF+C+ C GYR+ G G C D+NEC E
Sbjct: 693 LKASRPPVCEDIDECRDPSSCPDGKCENKPGSFKCIACQPGYRSQG-GGACRDVNECAEG 751
Query: 844 KSVCQRGDCINTAGSYDCTCPDGFQ-LDDNKTCQDINECEHPGLCGPQGECLNTEGSFHC 902
S C G C N GS+ CTC G+ D ++C D++ECE +C G C NT GSF C
Sbjct: 752 -SPCSPGWCENLPGSFRCTCAQGYAPAPDGRSCLDVDECEAGDVCD-NGICSNTPGSFQC 809
Query: 903 VCQQGFSISADGRTCEDIDECVNNTVCDSHGFCDNTAGSFRCLCYQGFQAPQDGQGCVDV 962
C G+ +S D CEDIDEC C G C NT GS+RCLC QG + G+ C D+
Sbjct: 810 QCLSGYHLSRDRSHCEDIDECDFPAACIG-GDCINTNGSYRCLCPQGHRLV-GGRKCQDI 867
Query: 963 NECELLSGVC-GEAFCENVEGSFLCVCADENQEYSPMTGQCRSRTSTDLDVDVDQPKEEK 1021
+EC +C C+N++GS++CVC ++ ++P Q +V+QP K
Sbjct: 868 DECSQDPSLCLPHGACKNLQGSYVCVC---DEGFTPTQDQHGCE-------EVEQP-HHK 916
Query: 1022 KECYYNLNDASLCDNVLAPNVTKQECCCTSGAGWGDNCEIFPCPVLGTAEFTEMCPKGKG 1081
KECY N +D CD+VLA NVT+QECCC+ GAGWGD+CEI+PCPV +AEF +CP GKG
Sbjct: 917 KECYLNFDDTVFCDSVLATNVTQQECCCSLGAGWGDHCEIYPCPVYSSAEFHSLCPDGKG 976
Query: 1082 FVPAGESSSEAGGENYKDADECLLFGQEICKNGFCLNTRPGYECYCKQGTYYDPVKLQCF 1141
+ + G ++D DEC+LFG EICK G C+NT+PGYECYCKQG YYD L+C
Sbjct: 977 YTQ-DNNIVNYGIPAHRDIDECMLFGSEICKEGKCVNTQPGYECYCKQGFYYDGNLLECV 1035
Query: 1142 DMDECQDPSSCIDGQCVNTEGSYNCFCTHPMVLDASEKRCIRPAESN------------- 1188
D+DEC D S+C +G C NT G Y C CT P ++++C+ P E +
Sbjct: 1036 DVDECLDESNCRNGVCENTRGGYRCACTPPAEYSPAQRQCLSPEEMDVDECQDPAACRPG 1095
Query: 1189 ------------------------------EQIEETDVYQDLCWEHLSDEYVCSRPLVGK 1218
E +D+CW ++ +C+ PL G
Sbjct: 1096 RCVNLPGSYRCECRPPWVPGPSGRDCQLPESPAERAPERRDVCWSQRGEDGMCAGPLAGP 1155
Query: 1219 QTTYTECCCLYGEAWGMQCALCPLKDSDDYAQLCNIPVTGRRQPYGRDALVDFSEQYTPE 1278
T+ +CCC G WG QC CP + + G P + F +
Sbjct: 1156 ALTFDDCCCRQGRGWGAQCRPCPPRGA------------GSHCPTSQSESNSFW-----D 1198
Query: 1279 ADPYFI--QDRFLNSFEELQAEECGILNGCENGRCVRVQEGYTCDCFDGYHLDTAKMTCV 1336
P + R +S EE ++EC C +GRCV G C+C G+ LD ++ CV
Sbjct: 1199 TSPLLLGKPPRDEDSSEE-DSDEC----RCVSGRCVPRPGGAVCECPGGFQLDASRARCV 1253
Query: 1337 DVNECDELNNRMSLCKNAKCINTDGSYKCLCLPGYVPSDKPNYCTP 1382
D++EC ELN R LCK+ +C+NT GS++C+C G+ S C P
Sbjct: 1254 DIDECRELNQRGLLCKSERCVNTSGSFRCVCKAGFARSRPHGACVP 1299
Score = 180 bits (457), Expect = 7e-45
Identities = 152/575 (26%), Positives = 224/575 (38%), Gaps = 128/575 (22%)
Query: 836 DINECLEDKSVCQRGDCINTAGSYDCTCPDGFQLD-DNKTCQDINECEHPGLCGP-QGEC 893
+ +EC ++++C G+C+ Y C C G++ ++ C D+NECE CGP +G C
Sbjct: 574 ETDECRLNQNICGHGECVPGPPDYSCHCNPGYRSHPQHRYCVDVNECEAEP-CGPGRGIC 632
Query: 894 LNTEGSFHCVCQQGFS--ISADGRTCEDIDECVNNTVCDSHGFCDNTAGSFRCLCYQGFQ 951
+NT GS++C C +G+ + A GR+C D++EC +C GFC N G ++C CY G++
Sbjct: 633 MNTGGSYNCHCNRGYRLHVGAGGRSCVDLNECAKPHLCGDGGFCINFPGHYKCNCYPGYR 692
Query: 952 APQDGQG-CVDVNECELLSGVCGEAFCENVEGSFLCVCADENQEYSPMTGQCRSRTSTDL 1010
C D++EC S C + CEN GSF C+ S G CR
Sbjct: 693 LKASRPPVCEDIDECRDPSS-CPDGKCENKPGSFKCIACQPGYR-SQGGGACR------- 743
Query: 1011 DVDVDQPKEEKKECYYNLNDASLCDNVLAPNVTKQECCCTSGAGWGDNCEIFPCPVLGTA 1070
+ EC + S C GW CE P
Sbjct: 744 ---------DVNECA----EGSPCS-----------------PGW---CENLPGSF---- 766
Query: 1071 EFTEMCPKGKGFVPAGESSSEAGGENYKDADECLLFGQEICKNGFCLNTRPGYECYCKQG 1130
C +G+ PA + G + D DEC ++C NG C NT ++C C G
Sbjct: 767 ----RCTCAQGYAPAPD------GRSCLDVDECE--AGDVCDNGICSNTPGSFQCQCLSG 814
Query: 1131 TYYDPVKLQCFDMDECQDPSSCIDGQCVNTEGSYNCFCTHPMVLDASEKRCIRPAESNEQ 1190
+ + C D+DEC P++CI G C+NT GSY C C L K C +
Sbjct: 815 YHLSRDRSHCEDIDECDFPAACIGGDCINTNGSYRCLCPQGHRLVGGRK-C-------QD 866
Query: 1191 IEETDVYQDLCWEHLSDEYVCSRPLVGKQTTYTECCCLYGEAWGMQCALCPLKDSDDYAQ 1250
I+E LC H + + + Q +Y C C G P +D +
Sbjct: 867 IDECSQDPSLCLPHGACKNL--------QGSYV-CVCDEG--------FTPTQDQHGCEE 909
Query: 1251 LCNIPVTGRRQPYGRDALVDFSEQYTPEADPYFIQDRFLNSFEELQAEECGILNGCENGR 1310
+ QP+ + E Y D F + Q E C L
Sbjct: 910 V--------EQPHHK------KECYLNFDDTVFCDSVLATNVT--QQECCCSLGAGWGDH 953
Query: 1311 CVRVQEGYTCDCFD------------GYHLDTAKMTCV-----DVNECDELNNRMSLCKN 1353
C E Y C + GY D + D++EC + +CK
Sbjct: 954 C----EIYPCPVYSSAEFHSLCPDGKGYTQDNNIVNYGIPAHRDIDECMLFGSE--ICKE 1007
Query: 1354 AKCINTDGSYKCLCLPGYVPSDKPNYCTPLNTALN 1388
KC+NT Y+C C G+ C ++ L+
Sbjct: 1008 GKCVNTQPGYECYCKQGFYYDGNLLECVDVDECLD 1042
Score = 173 bits (438), Expect = 1e-42
Identities = 136/452 (30%), Positives = 188/452 (41%), Gaps = 84/452 (18%)
Query: 539 QVIAPTQVTEINECTVNPDIC-GAGHCINLPVRYTCICYEGYRFSEQQRKCVDID----- 592
+++ + +I+EC+ +P +C G C NL Y C+C EG+ ++ Q C +++
Sbjct: 857 RLVGGRKCQDIDECSQDPSLCLPHGACKNLQGSYVCVCDEGFTPTQDQHGCEEVEQPHHK 916
Query: 593 -EC------------------TQVQHLCSQG-----RCE------NTEGSFLCICPAGFM 622
EC TQ + CS G CE + F +CP G
Sbjct: 917 KECYLNFDDTVFCDSVLATNVTQQECCCSLGAGWGDHCEIYPCPVYSSAEFHSLCPDGKG 976
Query: 623 ASEEGTNCI--------DVDECLR--PDVCGEGHCVNTVGAFRCEYCDSG-YRMTQRGRC 671
+++ N + D+DEC+ ++C EG CVNT + C YC G Y C
Sbjct: 977 YTQDN-NIVNYGIPAHRDIDECMLFGSEICKEGKCVNTQPGYEC-YCKQGFYYDGNLLEC 1034
Query: 672 EDIDECLNPSTCPDEQCVNSPGSYQCVPCTEG--FRGWNGQCL-----DVDECLEPNVCA 724
D+DECL+ S C + C N+ G Y+C CT + QCL DVDEC +P C
Sbjct: 1035 VDVDECLDESNCRNGVCENTRGGYRCA-CTPPAEYSPAQRQCLSPEEMDVDECQDPAACR 1093
Query: 725 NGDCSNLEGSYMCSCHKGYTRTPDHKHC-------------RDIDECQQG--NLCVNGQC 769
G C NL GSY C C + P + C RD+ Q+G +C
Sbjct: 1094 PGRCVNLPGSYRCECRPPWVPGPSGRDCQLPESPAERAPERRDVCWSQRGEDGMCAGPLA 1153
Query: 770 KNTEGSFRCTCGQGYQLSAAKDQCEDIDECQHRHLCAHGQCRNTEGSFQCVCDQGYRASG 829
C C QG A QC C R +H C ++ D G
Sbjct: 1154 GPALTFDDCCCRQGRGWGA---QCR---PCPPRGAGSH--CPTSQSESNSFWDTSPLLLG 1205
Query: 830 LGDHCEDINECLEDKSVCQRGDCINTAGSYDCTCPDGFQLDDNKT-CQDINEC---EHPG 885
ED +E D+ C G C+ G C CP GFQLD ++ C DI+EC G
Sbjct: 1206 KPPRDEDSSEEDSDECRCVSGRCVPRPGGAVCECPGGFQLDASRARCVDIDECRELNQRG 1265
Query: 886 LCGPQGECLNTEGSFHCVCQQGFSISADGRTC 917
L C+NT GSF CVC+ GF+ S C
Sbjct: 1266 LLCKSERCVNTSGSFRCVCKAGFARSRPHGAC 1297
Score = 94.4 bits (233), Expect = 7e-19
Identities = 80/295 (27%), Positives = 113/295 (38%), Gaps = 55/295 (18%)
Query: 1114 GFCLNTRPGYECYCKQG--TYYDPVKLQCFDMDECQDPSSCIDGQ-CVNTEGSYNCFCTH 1170
G C+NT Y C+C +G + C D++EC P C DG C+N G Y C C
Sbjct: 630 GICMNTGGSYNCHCNRGYRLHVGAGGRSCVDLNECAKPHLCGDGGFCINFPGHYKCNCYP 689
Query: 1171 PMVLDASEKRCIRP--AESNEQIEETDVYQDLCWEHLSDEYVCSRPLVGKQTTYTECCCL 1228
L AS RP E ++ + D E+ + C G ++ C
Sbjct: 690 GYRLKAS-----RPPVCEDIDECRDPSSCPDGKCENKPGSFKCIACQPGYRSQGGGACRD 744
Query: 1229 YGE-AWGMQCALCPLKDSDDYAQLCNIPVTGRRQPYGRDALVDFSEQYTPEADPYFIQDR 1287
E A G C S + + N+P + R ++ Y P D D
Sbjct: 745 VNECAEGSPC-------SPGWCE--NLPGSFR---------CTCAQGYAPAPDGRSCLD- 785
Query: 1288 FLNSFEELQAEECGILNGCENGRCVRVQEGYTCDCFDGYHLDTAKMTCVDVNECDELNNR 1347
+EC + C+NG C + C C GYHL + C D++ECD
Sbjct: 786 ---------VDECEAGDVCDNGICSNTPGSFQCQCLSGYHLSRDRSHCEDIDECD----F 832
Query: 1348 MSLCKNAKCINTDGSYKCLCLPGY------------VPSDKPNYCTPLNTALNLE 1390
+ C CINT+GSY+CLC G+ S P+ C P NL+
Sbjct: 833 PAACIGGDCINTNGSYRCLCPQGHRLVGGRKCQDIDECSQDPSLCLPHGACKNLQ 887
Score = 86.3 bits (212), Expect = 2e-16
Identities = 64/230 (27%), Positives = 90/230 (39%), Gaps = 54/230 (23%)
Query: 1024 CYYNLNDASLCDNVLAPNVTKQECCCTS-GAGWGDNCEIFPCPVLGTAEFTEMCPKGKGF 1082
C+ + C + P +TKQE CC S G WG + + CP L ++T G
Sbjct: 279 CFQDTLPKQPCGSNPLPGLTKQEDCCGSIGTAWGQS-KCHKCPQL---QYT-------GV 327
Query: 1083 VPAGESSSEAGGENYKDADECLLFGQEICKNGFCLNTRPGYECYCKQGTYYDPVKLQCFD 1142
G E G + C QG Y C D
Sbjct: 328 QKPGPVRGEVGAD-------------------------------CPQG-YKRLNSTHCQD 355
Query: 1143 MDECQDPSSCIDGQCVNTEGSYNCFCTHPMVLDASEKRCIRPAESNEQIEETDVYQDLCW 1202
++EC P C G C+N GSY C C L S +CI A+ E+ + LC+
Sbjct: 356 INECAMPGVCRHGDCLNNPGSYRCVCPPGHSLGPSRTQCI--ADKPEE-------KSLCF 406
Query: 1203 EHLSDEYVCSRPLVGKQTTYTECCCLYGEAWGMQCALCPLKDSDDYAQLC 1252
+S E+ C PL + T CCC G+AWG +C CP + + ++C
Sbjct: 407 RLVSPEHQCQHPLTTRLTRQL-CCCSVGKAWGARCQRCPTDGTAAFKEIC 455
Score = 67.8 bits (164), Expect = 7e-11
Identities = 30/76 (39%), Positives = 40/76 (52%), Gaps = 3/76 (3%)
Query: 559 CGAGHCINLPVRYTCICYEGYRFSEQQRKCVDIDECTQVQH---LCSQGRCENTEGSFLC 615
C +G C+ P C C G++ + +CVDIDEC ++ LC RC NT GSF C
Sbjct: 1223 CVSGRCVPRPGGAVCECPGGFQLDASRARCVDIDECRELNQRGLLCKSERCVNTSGSFRC 1282
Query: 616 ICPAGFMASEEGTNCI 631
+C AGF S C+
Sbjct: 1283 VCKAGFARSRPHGACV 1298
Score = 48.1 bits (113), Expect = 6e-05
Identities = 26/77 (33%), Positives = 38/77 (49%), Gaps = 9/77 (11%)
Query: 270 KCPKKPSYHGYNQMMECLPGYKR-VNNTFCQDINEC----QLQGVCPNGECLNTMGSYRC 324
+C +P + EC G++ + C DI+EC Q +C + C+NT GS+RC
Sbjct: 1227 RCVPRPG----GAVCECPGGFQLDASRARCVDIDECRELNQRGLLCKSERCVNTSGSFRC 1282
Query: 325 TCKIGFGPDPTFSSCVP 341
CK GF +CVP
Sbjct: 1283 VCKAGFARSRPHGACVP 1299
Score = 42.4 bits (98), Expect = 0.003
Identities = 20/52 (38%), Positives = 30/52 (57%), Gaps = 7/52 (13%)
Query: 1321 DCFDGY-HLDTAKMTCVDVNECDELNNRMSLCKNAKCINTDGSYKCLCLPGY 1371
DC GY L++ C D+NEC +C++ C+N GSY+C+C PG+
Sbjct: 340 DCPQGYKRLNSTH--CQDINECA----MPGVCRHGDCLNNPGSYRCVCPPGH 385
Score = 39.7 bits (91), Expect = 0.020
Identities = 35/140 (25%), Positives = 53/140 (37%), Gaps = 27/140 (19%)
Query: 1201 CWEHLSDEYVC-SRPLVGKQTTYTECCCLYGEAWGM-QCALCPLKDSDDYAQLCNIPVTG 1258
C++ + C S PL G T +CC G AWG +C CP + TG
Sbjct: 279 CFQDTLPKQPCGSNPLPGL-TKQEDCCGSIGTAWGQSKCHKCP-----------QLQYTG 326
Query: 1259 RRQP--YGRDALVDFSEQYTPEADPYFIQDRFLNSFEELQAEECGILNGCENGRCVRVQE 1316
++P + D + Y + LNS EC + C +G C+
Sbjct: 327 VQKPGPVRGEVGADCPQGY-----------KRLNSTHCQDINECAMPGVCRHGDCLNNPG 375
Query: 1317 GYTCDCFDGYHLDTAKMTCV 1336
Y C C G+ L ++ C+
Sbjct: 376 SYRCVCPPGHSLGPSRTQCI 395
Score = 38.9 bits (89), Expect = 0.035
Identities = 36/143 (25%), Positives = 53/143 (37%), Gaps = 25/143 (17%)
Query: 253 EDCCGTVGTSWGFNKCQKCPKK-------PSYHGYNQMMECLPGY----KRVNNTFCQDI 301
+DCC G WG +C+ CP + S N + P R ++ +D
Sbjct: 1160 DDCCCRQGRGWGA-QCRPCPPRGAGSHCPTSQSESNSFWDTSPLLLGKPPRDEDSSEEDS 1218
Query: 302 NECQLQGVCPNGECLNTMGSYRCTCKIGFGPDPTFSSCVPDPPVISEEKGPCYRLVSSGR 361
+EC+ C +G C+ G C C GF D + + CV + C L G
Sbjct: 1219 DECR----CVSGRCVPRPGGAVCECPGGFQLDASRARCV--------DIDECRELNQRGL 1266
Query: 362 QCMHPLSVHLTKQL-CCCSVGKA 383
C V+ + C C G A
Sbjct: 1267 LCKSERCVNTSGSFRCVCKAGFA 1289
Score = 37.7 bits (86), Expect = 0.078
Identities = 15/47 (31%), Positives = 22/47 (46%)
Query: 1338 VNECDELNNRMSLCKNAKCINTDGSYKCLCLPGYVPSDKPNYCTPLN 1384
V E DE ++C + +C+ Y C C PGY + YC +N
Sbjct: 572 VTETDECRLNQNICGHGECVPGPPDYSCHCNPGYRSHPQHRYCVDVN 618
>gi|24430141 fibrillin 1 precursor [Homo sapiens]
Length = 2871
Score = 552 bits (1422), Expect = e-157
Identities = 311/843 (36%), Positives = 428/843 (50%), Gaps = 90/843 (10%)
Query: 547 TEINECTVNPDICGAGHCINLPVRYTCICYEGYRFSEQQRK-CVDIDECTQVQHLCSQGR 605
T+I+EC ++PD+CG G C+N P + C C EGY K C+DIDEC + LC G
Sbjct: 1069 TDIDECRISPDLCGRGQCVNTPGDFECKCDEGYESGFMMMKNCMDIDECQRDPLLCRGGV 1128
Query: 606 CENTEGSFLCICPAGFMASEEGTNCIDVDEC-LRPDVCGEGHCVNTVGAFRCEYCDSGYR 664
C NTEGS+ C CP G S + CID++EC L +C G CVN +G ++C C+ GY
Sbjct: 1129 CHNTEGSYRCECPPGHQLSPNISACIDINECELSAHLCPNGRCVNLIGKYQCA-CNPGYH 1187
Query: 665 MT-QRGRCEDIDECLNPSTCPDEQCVNSPGSYQCVPCTEGFRGWNGQ--CLDVDECLE-P 720
T R C DIDEC + + C NS GSY+C C GF Q C D+DEC + P
Sbjct: 1188 STPDRLFCVDIDECSIMNGGCETFCTNSEGSYEC-SCQPGFALMPDQRSCTDIDECEDNP 1246
Query: 721 NVCANGDCSNLEGSYMCSCHKGYTRTPDHKHCRDIDECQQG-NLCVNGQCKNTEGSFRCT 779
N+C G C+N+ G Y C C+ G+ + D K C D++EC N+C++G C+NT+GSF C
Sbjct: 1247 NICDGGQCTNIPGEYRCLCYDGFMASEDMKTCVDVNECDLNPNICLSGTCENTKGSFICH 1306
Query: 780 CGQGYQLSAAKDQCEDIDECQ-HRHLCA-HGQCRNTEGSFQCVCDQGYRASGLGDHCEDI 837
C GY K C DI+EC+ H C H C NT GSF+C C G+ G+ C D+
Sbjct: 1307 CDMGYSGKKGKTGCTDINECEIGAHNCGKHAVCTNTAGSFKCSCSPGWIGDGI--KCTDL 1364
Query: 838 NECLEDKSVC-QRGDCINTAGSYDCTCPDGFQLDDNKTCQDINEC-EHPGLCGPQGECLN 895
+EC +C Q DC NT GSY C C +G+ D TC D++EC E+ LCG G+CLN
Sbjct: 1365 DECSNGTHMCSQHADCKNTMGSYRCLCKEGYT-GDGFTCTDLDECSENLNLCG-NGQCLN 1422
Query: 896 TEGSFHCVCQQGFSISADGRTCEDIDECVNNTVCDSHGFCDNTAGSFRCLCYQGFQAPQD 955
G + C C GF SADG+ CEDIDEC +C G C N G FRC C G++ +
Sbjct: 1423 APGGYRCECDMGFVPSADGKACEDIDECSLPNIC-VFGTCHNLPGLFRCECEIGYELDRS 1481
Query: 956 GQGCVDVNECELLSGVCGEAFCENVEGSFLCVCADENQEYSPMTGQCRSRTSTDLDVDVD 1015
G C DVNEC L C C N GS++C C + E +P C S + +D+
Sbjct: 1482 GGNCTDVNEC-LDPTTCISGNCVNTPGSYICDCPPDF-ELNPTRVGCVDTRSGNCYLDI- 1538
Query: 1016 QPKEEKKECYYNLNDASLCDNVLAPNVTKQECCCTSGAGWGDNCEIFPCPVLGTAEFTEM 1075
+P+ + N + C N + V+K CCC+ G WG CE+ CP + T+E+ +
Sbjct: 1539 RPRGD--------NGDTACSNEIGVGVSKASCCCSLGKAWGTPCEM--CPAVNTSEYKIL 1588
Query: 1076 CPKGKGFVPAGESSSEAGGENYKDADECLLFGQEI---CKNGFCLNTRPGYECYCKQGTY 1132
CP G+GF P + +D DEC QE+ C+ G C+NT ++C C G Y
Sbjct: 1589 CPGGEGFRPNPITVI------LEDIDEC----QELPGLCQGGKCINTFGSFQCRCPTGYY 1638
Query: 1133 YDPVKLQCFDMDECQDPSSCIDGQCVNTEGSYNCFCTHPMVLDASEKRCIRPAESNEQIE 1192
+ C D++EC+ P C G C NT G+Y C C + C+
Sbjct: 1639 LNEDTRVCDDVNECETPGICGPGTCYNTVGNYTCICPPDYMQVNGGNNCM---------- 1688
Query: 1193 ETDVYQDLCWE-HLSDEYVCSRPLVGKQTTYTECCCLY--GEAWGMQCALCPLKDSDDYA 1249
D+ + LC+ + +D C L+ T CCC Y G AW C CP+ +D++A
Sbjct: 1689 --DMRRSLCYRNYYADNQTCDGELLFNMTKKM-CCCSYNIGRAWNKPCEQCPIPSTDEFA 1745
Query: 1250 QLCNIPVTGRRQPYGRDALVDFSEQYTPEADPYFIQDRFLNSFEELQAEECGILNG-CEN 1308
LC P F+ D + + +EC + G CEN
Sbjct: 1746 TLCG------------------------SQRPGFVIDIYTGL--PVDIDECREIPGVCEN 1779
Query: 1309 GRCVRVQEGYTCDCFDGYHLDTAKMTCVDVNECDELNNRMSLCKNAKCINTDGSYKCLCL 1368
G C+ + + C+C G+ + + C D++EC N +NA+CINT GSY+C C
Sbjct: 1780 GVCINMVGSFRCECPVGFFYNDKLLVCEDIDEC---QNGPVCQRNAECINTAGSYRCDCK 1836
Query: 1369 PGY 1371
PGY
Sbjct: 1837 PGY 1839
Score = 480 bits (1236), Expect = e-135
Identities = 293/879 (33%), Positives = 417/879 (47%), Gaps = 113/879 (12%)
Query: 545 QVTEINECTVNPDICGAGHCINLPVRYTCICYEGYRFSEQQRKCVDIDECTQVQHLCSQG 604
Q + NEC P+IC G CI+ + C+C+ G++ ++ Q C+DI+EC + C G
Sbjct: 1846 QCNDRNECQEIPNICSHGQCIDTVGSFYCLCHTGFKTNDDQTMCLDINECER--DACGNG 1903
Query: 605 RCENTEGSFLCICPAGFMASEEGTNCIDVDECL--RPDVCGEGHCVNTVGAFRCEYCDSG 662
C NT GSF C C GF+ S +CIDVDEC ++C G C+NTVG+F+C+ C+ G
Sbjct: 1904 TCRNTIGSFNCRCNHGFILSHNN-DCIDVDECASGNGNLCRNGQCINTVGSFQCQ-CNEG 1961
Query: 663 YRMTQRGR-CEDIDECL-NPSTCPDEQCVNSPGSYQCVPCTEGFRGWNGQCLDVDECLE- 719
Y + GR C DI+ECL P C C N GSY+C+ C G+ N +C D+DEC+E
Sbjct: 1962 YEVAPDGRTCVDINECLLEPRKCAPGTCQNLDGSYRCI-CPPGYSLQNEKCEDIDECVEE 2020
Query: 720 PNVCANGDCSNLEGSYMCSCHKGYTRTPDHKHCRDI--DECQ---QGNLCVNGQCKN--- 771
P +CA G CSN EGS+ C C +G++ + + C+D+ C +G C + + +N
Sbjct: 2021 PEICALGTCSNTEGSFKCLCPEGFSLSSSGRRCQDLRMSYCYAKFEGGKCSSPKSRNHSK 2080
Query: 772 ----------------------TEGSFRCTCGQGYQLSAAKDQCE-DIDECQHRHLCAHG 808
+ +FR C G + D D+DEC+ +C HG
Sbjct: 2081 QECCCALKGEGWGDPCELCPTEPDEAFRQICPYGSGIIVGPDDSAVDMDECKEPDVCKHG 2140
Query: 809 QCRNTEGSFQCVCDQGYRASGLGDHCEDINECLEDKSVCQRGDCINTAGSYDCTCPDGFQ 868
QC NT+GS++C C GY +G + C D +EC C G C N G ++CTC +GF+
Sbjct: 2141 QCINTDGSYRCECPFGYILAG--NECVDTDECSVGNP-CGNGTCKNVIGGFECTCEEGFE 2197
Query: 869 LDDNKTCQDINEC-EHPGLCGPQGECLNTEGSFHCVCQQGFSISADGRTCEDIDECVN-- 925
TC+DINEC ++P LC + C+NT GS+ C C G+ + D R C+D DEC
Sbjct: 2198 PGPMMTCEDINECAQNPLLCAFR--CVNTYGSYECKCPVGYVLREDRRMCKDEDECEEGK 2255
Query: 926 NTVCDSHGFCDNTAGSFRCLCYQGFQAPQDGQGCVDVNECELLSGVCGEAFCENVEGSFL 985
+ + C N G++ C+C G+Q DG+GCVD NEC+ G+C C N GS+
Sbjct: 2256 HDCTEKQMECKNLIGTYMCICGPGYQRRPDGEGCVDENECQTKPGICENGRCLNTRGSYT 2315
Query: 986 CVCADENQEYSPMTGQCRSRTSTDLDVDVDQPKEEKKECYYNLNDASLCDNVLAPNVTKQ 1045
C C D SP +C +V Q C ++ + VTK
Sbjct: 2316 CECND-GFTASPNQDECLDNREGYCFTEVLQ-----NMCQIGSSNRN--------PVTKS 2361
Query: 1046 ECCCTSGAGWGDNCEIFPCPVLGTAEFTEMCPKGKGFVPAGESSSEAGGENYKDADECLL 1105
ECCC G GWG +CEI CP GT F ++CP G+GF+ G D DEC +
Sbjct: 2362 ECCCDGGRGWGPHCEI--CPFQGTVAFKKLCPHGRGFMTNG-----------ADIDECKV 2408
Query: 1106 FGQEICKNGFCLNTRPGYECYCKQGTYYDPVKLQCFDMDECQDPSSCIDGQCVNTEGSYN 1165
++C+NG C+N R Y C CK G D C D++EC + C NTEGSY
Sbjct: 2409 I-HDVCRNGECVNDRGSYHCICKTGYTPDITGTSCVDLNECNQAPKPCNFICKNTEGSYQ 2467
Query: 1166 CFCTHPMVLDASEKRCIRPAESNEQIEETDVYQDLCWEHLSDEYVCSRPLVGKQTTYTEC 1225
C C +L + C + ++E Q C +++C + G C
Sbjct: 2468 CSCPKGYILQEDGRSC-------KDLDECATKQHNC------QFLCVNTIGG-----FTC 2509
Query: 1226 CCLYGEAWGMQCALCPLKDSDDYAQLCNIPVTGRRQPYGRDALVDFSEQYTPEADPYFIQ 1285
C G + + + D LC + P +T E F
Sbjct: 2510 KCPPGFTQHHTSCIDNNECTSD-INLCGSKGICQNTP----------GSFTCECQRGFSL 2558
Query: 1286 DRFLNSFEELQAEECGILNGCENGRCVRVQEGYTCDCFDGYHLDTAKMTCVDVNECDELN 1345
D+ +S E++ +EC + C++G C + GY C C GY CVD NEC +
Sbjct: 2559 DQTGSSCEDV--DECEGNHRCQHG-CQNIIGGYRCSCPQGYLQHYQWNQCVDENECLSAH 2615
Query: 1346 NRMSLCKNAKCINTDGSYKCLCLPGYVPSDKPNYCTPLN 1384
+C A C NT GSYKC+C G+ C +N
Sbjct: 2616 ----ICGGASCHNTLGSYKCMCPAGFQYEQFSGGCQDIN 2650
Score = 466 bits (1198), Expect = e-131
Identities = 347/1220 (28%), Positives = 513/1220 (42%), Gaps = 187/1220 (15%)
Query: 231 GRCFQETIGSQCGKALPGLSKQED-CCGTVGTSWGFNKCQKCPKKPSYHGYNQMMECLPG 289
G CF C L G+ + CC TVG +WG + C+ CP +P C G
Sbjct: 184 GPCFTVISNQMCQGQLSGIVCTKTLCCATVGRAWG-HPCEMCPAQPH--------PCRRG 234
Query: 290 Y-KRVNNTFCQDINECQ-LQGVCPNGECLNTMGSYRCTCKIGFGPDPTFSSCVPDPPVIS 347
+ + CQD++ECQ + G+C G C+NT+GS+ C C G + C D S
Sbjct: 235 FIPNIRTGACQDVDECQAIPGLCQGGNCINTVGSFECKCPAGHKLNEVSQKC-EDIDECS 293
Query: 348 EEKGPCYRLVSSGRQCMHPLSVHLTKQLCCCSVGKAWGPHCEKCPLPGTAAFKEICPGGM 407
G C G +C + +S + C C G P +C ++ PG
Sbjct: 294 TIPGIC-----EGGECTNTVSSYF----CKCPPGFYTSPDGTRCI--------DVRPGYC 336
Query: 408 GYTVSGVHRRRPIHHHVGKGPVFVKPKNTQPVAKSTHPPPLPAKEEPVEALTFSREHGPG 467
++ + + K + P P + + +
Sbjct: 337 YTALTNGRCSNQLPQSITKMQCCCDAGRCWSPGVTVAPEMCPIRA--------TEDFNKL 388
Query: 468 VAEPEVATAPPEKEIPSLDQEKTKLEPGQPQLSPGISTIHLHPQFPGIVIEKTSPPVPVE 527
+ P V PE P L L P P PG PQ P P PVE
Sbjct: 389 CSVPMVIPGRPEYPPPPLGPIPPVL-PVPPGFPPG-------PQIP-------VPRPPVE 433
Query: 528 VAPEASTSSASQVIAPTQVTEINECTVNPDICGAGHCINLPVRYTCICYEGYRFSEQQRK 587
S + P VT+ C + +C G CI P C C +G++ + + +
Sbjct: 434 YL---YPSREPPRVLPVNVTDY--CQLVRYLCQNGRCIPTPGSCRCECNKGFQL-DLRGE 487
Query: 588 CVDIDECTQVQHLCSQGRCENTEGSFLCICPAGFMASEEGTNCIDVDECLRPD-VCGEGH 646
C+D+DEC ++ C+ G C N +GS+ C C AG+ ++ T C D+DECL+ +C G
Sbjct: 488 CIDVDECE--KNPCAGGECINNQGSYTCQCRAGYQSTLTRTECRDIDECLQNGRICNNGR 545
Query: 647 CVNTVGAFRCEYCDSGYRMTQRGR-CEDIDECLNPSTCPDEQCVNSPGSYQCVPCTEGFR 705
C+NT G+F C C++G+ +T+ G+ CED+DEC + C + C+N GS++C+ C GF+
Sbjct: 546 CINTDGSFHC-VCNAGFHVTRDGKNCEDMDECSIRNMCLNGMCINEDGSFKCI-CKPGFQ 603
Query: 706 -GWNGQ-CLDVDECLEPNVCANGDCSNLEGSYMCSCHKGYTRTPDHKHCRDI---DECQQ 760
+G+ C D++EC P +C NG C N +GSY C C G D + C D C
Sbjct: 604 LASDGRYCKDINECETPGICMNGRCVNTDGSYRCECFPGLAVGLDGRVCVDTHMRSTCYG 663
Query: 761 G---NLCVNGQ----------CKNTEGSF---------------RCTCGQGYQLSAAKDQ 792
G C+ C +TE +F + C G +++A
Sbjct: 664 GYKRGQCIKPLFGAVTKSECCCASTEYAFGEPCQPCPAQNSAEYQALCSSGPGMTSAG-- 721
Query: 793 CEDIDECQ-HRHLCAHGQCRNTEGSFQCVCDQGYRASGLGDHCEDINECLEDKSVCQRGD 851
DI+EC +C +G C N G+++C+C+ GY G +C DINEC+ + +C G
Sbjct: 722 -SDINECALDPDICPNGICENLRGTYKCICNSGYEVDSTGKNCVDINECVLNSLLCDNGQ 780
Query: 852 CINTAGSYDCTCPDGF-QLDDNKTCQDINECEHPGLCGPQGECLNTEGSFHCVCQQGFSI 910
C NT GS+ CTCP GF D KTC+DI+ECE G C N+ GSF C C ++
Sbjct: 781 CRNTPGSFVCTCPKGFIYKPDLKTCEDIDECESSPCI--NGVCKNSPGSFICECSSESTL 838
Query: 911 SADGRTC-EDIDECVNNTVCDSHGFCDNTAGSFRCLCYQGFQA------------PQDGQ 957
C E I TV D + + + C A P G+
Sbjct: 839 DPTKTICIETIKGTCWQTVIDGRCEININGATLKSQCCSSLGAAWGSPCTLCQVDPICGK 898
Query: 958 G--------CVDVNECELLSGVCGEAFCENVEGSFLCVCADENQEYSPMTGQCRSRTSTD 1009
G C D++ECE+ GVC C N GSF C C S MT R D
Sbjct: 899 GYSRIKGTQCEDIDECEVFPGVCKNGLCVNTRGSFKCQCP------SGMTLDATGRICLD 952
Query: 1010 LDVDVDQPKEEKKECYYNLNDASLCDNVLAPNVTKQECCCTSGAGWG-DNCEIFPCPVLG 1068
+ ++ C+ D C +A CCC+ GA WG + CE CP+
Sbjct: 953 IRLET---------CFLRYEDEE-CTLPIAGRHRMDACCCSVGAAWGTEECE--ECPMRN 1000
Query: 1069 TAEFTEMCPKGKGFVPAGESSSEAGGENYKDADECLLFGQEICKNGFCLNTRPGYECYCK 1128
T E+ E+CP+G GF ++ G +KD +EC + +C +G C NT ++C C
Sbjct: 1001 TPEYEELCPRGPGFATKEITN---GKPFFKDINECKMI-PSLCTHGKCRNTIGSFKCRCD 1056
Query: 1129 QGTYYDPVKLQCFDMDECQ-DPSSCIDGQCVNTEGSYNCFCTHPMVLDASEKRCIRPAES 1187
G D + C D+DEC+ P C GQCVNT G + C +C ES
Sbjct: 1057 SGFALDSEERNCTDIDECRISPDLCGRGQCVNTPGDFEC-------------KCDEGYES 1103
Query: 1188 NEQIEETDVYQDLCWEHLSDEYVCSRPLVGKQTTYTECCCLYGEAWGMQCALC-PLKDSD 1246
+ + + D C D +C + C C G + C + + +
Sbjct: 1104 GFMMMKNCMDIDECQR---DPLLCRGGVCHNTEGSYRCECPPGHQLSPNISACIDINECE 1160
Query: 1247 DYAQLCNIPVTGRRQPYGRDALVDFSEQYTPEADP--YFIQDRFLNSFEELQAEECGILN 1304
A LC P GR V+ +Y +P + DR + +EC I+N
Sbjct: 1161 LSAHLC---------PNGR--CVNLIGKYQCACNPGYHSTPDRLFC----VDIDECSIMN 1205
Query: 1305 GCENGRCVRVQEGYTCDCFDGYHLDTAKMTCVDVNECDELNNRMSLCKNAKCINTDGSYK 1364
G C + Y C C G+ L + +C D++EC++ N +C +C N G Y+
Sbjct: 1206 GGCETFCTNSEGSYECSCQPGFALMPDQRSCTDIDECEDNPN---ICDGGQCTNIPGEYR 1262
Query: 1365 CLCLPGYVPSDKPNYCTPLN 1384
CLC G++ S+ C +N
Sbjct: 1263 CLCYDGFMASEDMKTCVDVN 1282
Score = 447 bits (1150), Expect = e-125
Identities = 325/1064 (30%), Positives = 438/1064 (41%), Gaps = 266/1064 (25%)
Query: 523 PVPVEVAPEASTSSASQVIAPTQVTEINECTVNPDICGAGHCINLPVRYTCICYEGYRFS 582
P P + + E +S + ++INEC ++PDIC G C NL Y CIC GY
Sbjct: 698 PCPAQNSAEYQALCSSGPGMTSAGSDINECALDPDICPNGICENLRGTYKCICNSGYEVD 757
Query: 583 EQQRKCVDIDECTQVQHLCSQGRCENTEGSFLCICPAGFMASEEGTNCIDVDECLRPDVC 642
+ CVDI+EC LC G+C NT GSF+C CP GF+ + C D+DEC C
Sbjct: 758 STGKNCVDINECVLNSLLCDNGQCRNTPGSFVCTCPKGFIYKPDLKTCEDIDEC-ESSPC 816
Query: 643 GEGHCVNTVGAFRCEYCDSGYRM---------TQRGRCED--ID-EC---LNPSTCPDEQ 687
G C N+ G+F CE C S + T +G C ID C +N +T Q
Sbjct: 817 INGVCKNSPGSFICE-CSSESTLDPTKTICIETIKGTCWQTVIDGRCEININGATL-KSQ 874
Query: 688 CVNSPGSYQCVPCT---------EGFRGWNG-QCLDVDEC-LEPNVCANGDCSNLEGSYM 736
C +S G+ PCT +G+ G QC D+DEC + P VC NG C N GS+
Sbjct: 875 CCSSLGAAWGSPCTLCQVDPICGKGYSRIKGTQCEDIDECEVFPGVCKNGLCVNTRGSFK 934
Query: 737 CSCHKGYTRTPDHKHCRDI----------------------------------------D 756
C C G T + C DI +
Sbjct: 935 CQCPSGMTLDATGRICLDIRLETCFLRYEDEECTLPIAGRHRMDACCCSVGAAWGTEECE 994
Query: 757 ECQQGN------LCVNG-------------------QCKN-----TEGSFRCTCG----- 781
EC N LC G +CK T G R T G
Sbjct: 995 ECPMRNTPEYEELCPRGPGFATKEITNGKPFFKDINECKMIPSLCTHGKCRNTIGSFKCR 1054
Query: 782 --QGYQLSAAKDQCEDIDECQ-HRHLCAHGQCRNTEGSFQCVCDQGYRAS-GLGDHCEDI 837
G+ L + + C DIDEC+ LC GQC NT G F+C CD+GY + + +C DI
Sbjct: 1055 CDSGFALDSEERNCTDIDECRISPDLCGRGQCVNTPGDFECKCDEGYESGFMMMKNCMDI 1114
Query: 838 NECLEDKSVCQRGDCINTAGSYDCTCPDGFQLDDN-KTCQDINECEHPGLCGPQGECL-- 894
+EC D +C+ G C NT GSY C CP G QL N C DINECE P G C+
Sbjct: 1115 DECQRDPLLCRGGVCHNTEGSYRCECPPGHQLSPNISACIDINECELSAHLCPNGRCVNL 1174
Query: 895 ---------------------------------------NTEGSFHCVCQQGFSISADGR 915
N+EGS+ C CQ GF++ D R
Sbjct: 1175 IGKYQCACNPGYHSTPDRLFCVDIDECSIMNGGCETFCTNSEGSYECSCQPGFALMPDQR 1234
Query: 916 TCEDIDECVNN-TVCDSHGFCDNTAGSFRCLCYQGFQAPQDGQGCVDVNECELLSGVCGE 974
+C DIDEC +N +CD G C N G +RCLCY GF A +D + CVDVNEC+L +C
Sbjct: 1235 SCTDIDECEDNPNICDG-GQCTNIPGEYRCLCYDGFMASEDMKTCVDVNECDLNPNICLS 1293
Query: 975 AFCENVEGSFLCVCADENQEYSPMTGQCRSRTSTDLDV---------------------- 1012
CEN +GSF+C C + YS G+ + ++
Sbjct: 1294 GTCENTKGSFICHC---DMGYSGKKGKTGCTDINECEIGAHNCGKHAVCTNTAGSFKCSC 1350
Query: 1013 ------------DVDQPKEEKKECYYNLNDASLCDNVLAPNVTKQECCCTSG-AGWGDNC 1059
D+D+ C + + C N + C C G G G C
Sbjct: 1351 SPGWIGDGIKCTDLDECSNGTHMCSQHAD----CKNTMG----SYRCLCKEGYTGDGFTC 1402
Query: 1060 -EIFPCPVLGTAEFTEMCPKGK--------------GFVPAGESSSEAGGENYKDADECL 1104
++ C +E +C G+ GFVP+ A G+ +D DEC
Sbjct: 1403 TDLDEC-----SENLNLCGNGQCLNAPGGYRCECDMGFVPS------ADGKACEDIDECS 1451
Query: 1105 LFGQEICKNGFCLNTRPGYECYCKQGTYYDPVKLQCFDMDECQDPSSCIDGQCVNTEGSY 1164
L IC G C N + C C+ G D C D++EC DP++CI G CVNT GSY
Sbjct: 1452 L--PNICVFGTCHNLPGLFRCECEIGYELDRSGGNCTDVNECLDPTTCISGNCVNTPGSY 1509
Query: 1165 NCFCTHPMVLDASEKRCIRPAESNEQIEETDVYQDLCWEHLSDEYVCSRPLVGKQTTYTE 1224
C C L+ + C+ N Y D+ + + CS +G +
Sbjct: 1510 ICDCPPDFELNPTRVGCVDTRSGN-------CYLDIRPRGDNGDTACSNE-IGVGVSKAS 1561
Query: 1225 CCCLYGEAWGMQCALCPLKDSDDYAQLCNIPVTGRRQPYGRDALVDFSEQYTPEADPYFI 1284
CCC G+AWG C +CP ++ +Y LC P G E + P +
Sbjct: 1562 CCCSLGKAWGTPCEMCPAVNTSEYKILC---------PGG--------EGFRPNPITVIL 1604
Query: 1285 QDRFLNSFEELQAEECGILNG-CENGRCVRVQEGYTCDCFDGYHLDTAKMTCVDVNECDE 1343
+D +EC L G C+ G+C+ + C C GY+L+ C DVNEC+
Sbjct: 1605 ED----------IDECQELPGLCQGGKCINTFGSFQCRCPTGYYLNEDTRVCDDVNECE- 1653
Query: 1344 LNNRMSLCKNAKCINTDGSYKCLCLPGYVPSDKPNYCTPLNTAL 1387
+C C NT G+Y C+C P Y+ + N C + +L
Sbjct: 1654 ---TPGICGPGTCYNTVGNYTCICPPDYMQVNGGNNCMDMRRSL 1694
Score = 435 bits (1119), Expect = e-121
Identities = 298/931 (32%), Positives = 406/931 (43%), Gaps = 159/931 (17%)
Query: 577 EGYRFSEQQRKCVDIDECTQVQHLCSQGRCENTEGSFLCICPAGFMASEEGTNCIDVDEC 636
EG+R + DIDEC ++ LC G+C NT GSF C CP G+ +E+ C DV+EC
Sbjct: 1593 EGFRPNPITVILEDIDECQELPGLCQGGKCINTFGSFQCRCPTGYYLNEDTRVCDDVNEC 1652
Query: 637 LRPDVCGEGHCVNTVGAFRCEYCDSGYRMTQRGR-CEDIDECL-------NPSTCPDEQC 688
P +CG G C NTVG + C C Y G C D+ L + TC E
Sbjct: 1653 ETPGICGPGTCYNTVGNYTC-ICPPDYMQVNGGNNCMDMRRSLCYRNYYADNQTCDGELL 1711
Query: 689 VNSPGSYQCVPCTEGFRGWNGQC-------------------------------LDVDEC 717
N C G R WN C +D+DEC
Sbjct: 1712 FNMTKKMCCCSYNIG-RAWNKPCEQCPIPSTDEFATLCGSQRPGFVIDIYTGLPVDIDEC 1770
Query: 718 LE-PNVCANGDCSNLEGSYMCSCHKGYTRTPDHKHCRDIDECQQGNLCV-NGQCKNTEGS 775
E P VC NG C N+ GS+ C C G+ C DIDECQ G +C N +C NT GS
Sbjct: 1771 REIPGVCENGVCINMVGSFRCECPVGFFYNDKLLVCEDIDECQNGPVCQRNAECINTAGS 1830
Query: 776 FRCTCGQGYQLSAAKDQCEDIDECQH-RHLCAHGQCRNTEGSFQCVCDQGYRASGLGDHC 834
+RC C GY+ ++ QC D +ECQ ++C+HGQC +T GSF C+C G++ + C
Sbjct: 1831 YRCDCKPGYRFTST-GQCNDRNECQEIPNICSHGQCIDTVGSFYCLCHTGFKTNDDQTMC 1889
Query: 835 EDINECLEDKSVCQRGDCINTAGSYDCTCPDGFQLDDNKTCQDINECE--HPGLCGPQGE 892
DINEC ++ C G C NT GS++C C GF L N C D++EC + LC G+
Sbjct: 1890 LDINEC--ERDACGNGTCRNTIGSFNCRCNHGFILSHNNDCIDVDECASGNGNLCR-NGQ 1946
Query: 893 CLNTEGSFHCVCQQGFSISADGRTCEDIDECVNNTVCDSHGFCDNTAGSFRCLCYQGFQA 952
C+NT GSF C C +G+ ++ DGRTC DI+EC+ + G C N GS+RC+C G+
Sbjct: 1947 CINTVGSFQCQCNEGYEVAPDGRTCVDINECLLEPRKCAPGTCQNLDGSYRCICPPGYSL 2006
Query: 953 PQDGQGCVDVNECELLSGVCGEAFCENVEGSFLCVCADENQEYSPMTGQCRSRTSTDLDV 1012
+ C D++EC +C C N EGSF C+C E S +C+ DL +
Sbjct: 2007 --QNEKCEDIDECVEEPEICALGTCSNTEGSFKCLCP-EGFSLSSSGRRCQ-----DLRM 2058
Query: 1013 DVDQPKEEKKECYYNLNDASLCDNVLAPNVTKQECCCT-SGAGWGDNCEIFPCPVLGTAE 1071
CY + C + + N +KQECCC G GWGD CE+ CP
Sbjct: 2059 SY---------CYAKF-EGGKCSSPKSRNHSKQECCCALKGEGWGDPCEL--CPTEPDEA 2106
Query: 1072 FTEMCPKGKGFVPAGESSSEAGGENYKDADEC--------------------LLFGQEI- 1110
F ++CP G G + G S + K+ D C +L G E
Sbjct: 2107 FRQICPYGSGII-VGPDDSAVDMDECKEPDVCKHGQCINTDGSYRCECPFGYILAGNECV 2165
Query: 1111 ----------CKNGFCLNTRPGYECYCKQGTYYDPVKLQCFDMDEC-QDPSSCIDGQCVN 1159
C NG C N G+EC C++G P+ + C D++EC Q+P C +CVN
Sbjct: 2166 DTDECSVGNPCGNGTCKNVIGGFECTCEEGFEPGPM-MTCEDINECAQNPLLCAF-RCVN 2223
Query: 1160 TEGSYNCFCTHPMVLDASEKRCIRPAESNEQIEETDVYQDLCWEHLSDEYVC-------S 1212
T GSY C C VL + C E E + Q C ++L Y+C
Sbjct: 2224 TYGSYECKCPVGYVLREDRRMCKDEDECEEGKHDCTEKQMEC-KNLIGTYMCICGPGYQR 2282
Query: 1213 RPLVGKQTTYTECCCLYGEAWGMQCA------LCPLKD--------------------SD 1246
RP EC G +C C D ++
Sbjct: 2283 RPDGEGCVDENECQTKPGICENGRCLNTRGSYTCECNDGFTASPNQDECLDNREGYCFTE 2342
Query: 1247 DYAQLCNIPVTGRRQPYGRDALVDFSEQYTPEADPYFIQDRFLNSFEEL----------- 1295
+C I + R + D + P + Q +F++L
Sbjct: 2343 VLQNMCQIGSSNRNPVTKSECCCDGGRGWGPHCEICPFQGTV--AFKKLCPHGRGFMTNG 2400
Query: 1296 -QAEECGILNG-CENGRCVRVQEGYTCDCFDGYHLDTAKMTCVDVNECDELNNRMSLCKN 1353
+EC +++ C NG CV + Y C C GY D +CVD+NEC N C N
Sbjct: 2401 ADIDECKVIHDVCRNGECVNDRGSYHCICKTGYTPDITGTSCVDLNEC---NQAPKPC-N 2456
Query: 1354 AKCINTDGSYKCLCLPGYVPSDKPNYCTPLN 1384
C NT+GSY+C C GY+ + C L+
Sbjct: 2457 FICKNTEGSYQCSCPKGYILQEDGRSCKDLD 2487
Score = 408 bits (1048), Expect = e-113
Identities = 268/873 (30%), Positives = 375/873 (42%), Gaps = 153/873 (17%)
Query: 547 TEINECTVNPDICGAGHCINLPVRYTCICYEGYRFSEQQRKCVDIDECTQVQHLCSQGRC 606
T+I+EC NP+IC G C N+P Y C+CY+G+ SE + CVD++EC ++C G C
Sbjct: 1237 TDIDECEDNPNICDGGQCTNIPGEYRCLCYDGFMASEDMKTCVDVNECDLNPNICLSGTC 1296
Query: 607 ENTEGSFLCICPAGFMASEEGTNCIDVDEC-LRPDVCGE-GHCVNTVGAFRCEYCDSGYR 664
ENT+GSF+C C G+ + T C D++EC + CG+ C NT G+F+C C G+
Sbjct: 1297 ENTKGSFICHCDMGYSGKKGKTGCTDINECEIGAHNCGKHAVCTNTAGSFKCS-CSPGW- 1354
Query: 665 MTQRGRCEDIDECLNPSTCPDEQ--CVNSPGSYQCVPCTEGFRGWNGQCLDVDECLEP-N 721
+ +C D+DEC N + + C N+ GSY+C+ C EG+ G C D+DEC E N
Sbjct: 1355 IGDGIKCTDLDECSNGTHMCSQHADCKNTMGSYRCL-CKEGYTGDGFTCTDLDECSENLN 1413
Query: 722 VCANGDCSNLEGSYMCSCHKGYTRTPDHKHCRDIDECQQGNLCVNGQCKNTEGSFRCTCG 781
+C NG C N G Y C C G+ + D K C DIDEC N+CV G C N G FRC C
Sbjct: 1414 LCGNGQCLNAPGGYRCECDMGFVPSADGKACEDIDECSLPNICVFGTCHNLPGLFRCECE 1473
Query: 782 QGYQLSAAKDQCEDIDECQHRHLCAHGQCRNTEGSFQCVCDQGYRASGLGDHCEDINE-- 839
GY+L + C D++EC C G C NT GS+ C C + + C D
Sbjct: 1474 IGYELDRSGGNCTDVNECLDPTTCISGNCVNTPGSYICDCPPDFELNPTRVGCVDTRSGN 1533
Query: 840 ---------------CLEDKSV------------------CQRGDCINTAGSYDCTCPDG 866
C + V C+ +NT+ Y CP G
Sbjct: 1534 CYLDIRPRGDNGDTACSNEIGVGVSKASCCCSLGKAWGTPCEMCPAVNTS-EYKILCPGG 1592
Query: 867 FQLDDNK---TCQDINEC-EHPGLCGPQGECLNTEGSFHCVCQQGFSISADGRTCEDIDE 922
N +DI+EC E PGLC G+C+NT GSF C C G+ ++ D R C+D++E
Sbjct: 1593 EGFRPNPITVILEDIDECQELPGLC-QGGKCINTFGSFQCRCPTGYYLNEDTRVCDDVNE 1651
Query: 923 CVNNTVCDSHGFCDNTAGSFRCLCYQGFQAPQDGQGCVDVNECELLSGVCGEAFCENVEG 982
C +C G C NT G++ C+C + G C+D+
Sbjct: 1652 CETPGIC-GPGTCYNTVGNYTCICPPDYMQVNGGNNCMDMRRS----------------- 1693
Query: 983 SFLCVCADENQEYSPMTGQCRSRTSTDLDVDVDQPKEEKKECYYNLNDASLCDNVLAPNV 1042
LC + Y C E +N+ C
Sbjct: 1694 --LCY-----RNYYADNQTCDG------------------ELLFNMTKKMCC-------- 1720
Query: 1043 TKQECCCTSGAGWGDNCEIFPCPVLGTAEFTEMCPKGK-GFVPAGESSSEAGGENYKDAD 1101
C G W CE CP+ T EF +C + GFV + D D
Sbjct: 1721 ----CSYNIGRAWNKPCE--QCPIPSTDEFATLCGSQRPGFVIDIYTGLPV------DID 1768
Query: 1102 ECLLFGQEICKNGFCLNTRPGYECYCKQGTYYDPVKLQCFDMDECQDPSSC-IDGQCVNT 1160
EC +C+NG C+N + C C G +Y+ L C D+DECQ+ C + +C+NT
Sbjct: 1769 ECREI-PGVCENGVCINMVGSFRCECPVGFFYNDKLLVCEDIDECQNGPVCQRNAECINT 1827
Query: 1161 EGSYNCFCTHPMVLDASEKRCIRPAESNEQIEETDVYQDLCWEHLSDEYVCSRPLVGKQT 1220
GSY C C P S +C N++ E ++ +CS
Sbjct: 1828 AGSYRCDC-KPGYRFTSTGQC------NDRNECQEI-----------PNICSHGQCIDTV 1869
Query: 1221 TYTECCCLYGEAWGMQCALCPLKDSDDYAQLCNIPVTGRRQPYGRDALVDFSEQYTPEAD 1280
C C G K +DD +I R G + + +
Sbjct: 1870 GSFYCLCHTG-----------FKTNDDQTMCLDINEC-ERDACGNGTCRNTIGSFNCRCN 1917
Query: 1281 PYFIQDRFLNSFEELQAEECGILNG--CENGRCVRVQEGYTCDCFDGYHLDTAKMTCVDV 1338
FI ++ + + +EC NG C NG+C+ + C C +GY + TCVD+
Sbjct: 1918 HGFI---LSHNNDCIDVDECASGNGNLCRNGQCINTVGSFQCQCNEGYEVAPDGRTCVDI 1974
Query: 1339 NECDELNNRMSLCKNAKCINTDGSYKCLCLPGY 1371
NEC L R C C N DGSY+C+C PGY
Sbjct: 1975 NEC-LLEPRK--CAPGTCQNLDGSYRCICPPGY 2004
Score = 315 bits (808), Expect = 1e-85
Identities = 211/621 (33%), Positives = 276/621 (44%), Gaps = 113/621 (18%)
Query: 589 VDIDECTQVQHLCSQGRCENTEGSFLCICPAGFMASEEGTNCIDVDECLRPDVCGEGHCV 648
VD+DEC + +C G+C NT+GS+ C CP G++ + G C+D DEC + CG G C
Sbjct: 2126 VDMDECKEPD-VCKHGQCINTDGSYRCECPFGYILA--GNECVDTDECSVGNPCGNGTCK 2182
Query: 649 NTVGAFRCEYCDSGYRMTQRGRCEDIDECL-NPSTCPDEQCVNSPGSYQCVPCTEGF--R 705
N +G F C C+ G+ CEDI+EC NP C +CVN+ GSY+C C G+ R
Sbjct: 2183 NVIGGFECT-CEEGFEPGPMMTCEDINECAQNPLLCAF-RCVNTYGSYEC-KCPVGYVLR 2239
Query: 706 GWNGQCLDVDECLE-PNVCANG--DCSNLEGSYMCSCHKGYTRTPDHKHCRDIDECQ-QG 761
C D DEC E + C +C NL G+YMC C GY R PD + C D +ECQ +
Sbjct: 2240 EDRRMCKDEDECEEGKHDCTEKQMECKNLIGTYMCICGPGYQRRPDGEGCVDENECQTKP 2299
Query: 762 NLCVNGQCKNTEGSFRCTCGQGYQLSAAKDQCEDIDECQH-----RHLCAHGQC-RNTEG 815
+C NG+C NT GS+ C C G+ S +D+C D E +++C G RN
Sbjct: 2300 GICENGRCLNTRGSYTCECNDGFTASPNQDECLDNREGYCFTEVLQNMCQIGSSNRNPVT 2359
Query: 816 SFQCVCDQGYRASGLGDHCE-------------------------DINECLEDKSVCQRG 850
+C CD G G G HCE DI+EC VC+ G
Sbjct: 2360 KSECCCDGG---RGWGPHCEICPFQGTVAFKKLCPHGRGFMTNGADIDECKVIHDVCRNG 2416
Query: 851 DCINTAGSYDCTCPDGFQLDDNKT-CQDINECEH-PGLCGPQGECLNTEGSFHCVCQQGF 908
+C+N GSY C C G+ D T C D+NEC P C C NTEGS+ C C +G+
Sbjct: 2417 ECVNDRGSYHCICKTGYTPDITGTSCVDLNECNQAPKPCN--FICKNTEGSYQCSCPKGY 2474
Query: 909 SISADGRTCEDIDECVNNTVCDSHGFCDNTAGSFRCLCYQGFQAPQDGQGCVDVNECELL 968
+ DGR+C+D+DEC + C NT G F C C GF Q C+D NEC
Sbjct: 2475 ILQEDGRSCKDLDECATKQH-NCQFLCVNTIGGFTCKCPPGFT--QHHTSCIDNNECTSD 2531
Query: 969 SGVCG-EAFCENVEGSFLCVCADENQEYSPMTGQCRSRTSTDLDVDVDQPKEEKKECYYN 1027
+CG + C+N GSF C C G +T + + DVD EC N
Sbjct: 2532 INLCGSKGICQNTPGSFTCEC---------QRGFSLDQTGSSCE-DVD-------ECEGN 2574
Query: 1028 LNDASLCDNVLAPNVTKQECCCTSGAGWGDNCEIFPCPVLGTAEFTEMCPKGKGFVPAGE 1087
C N++ G C CP+G
Sbjct: 2575 HRCQHGCQNIIG----------------GYRCS---------------CPQGY------- 2596
Query: 1088 SSSEAGGENYKDADECLLFGQEICKNGFCLNTRPGYECYCKQGTYYDPVKLQCFDMDECQ 1147
D +ECL IC C NT Y+C C G Y+ C D++EC
Sbjct: 2597 -LQHYQWNQCVDENECL--SAHICGGASCHNTLGSYKCMCPAGFQYEQFSGGCQDINECG 2653
Query: 1148 DPSSCIDGQCVNTEGSYNCFC 1168
+ C NTEG Y C C
Sbjct: 2654 SAQAPCSYGCSNTEGGYLCGC 2674
Score = 309 bits (791), Expect = 1e-83
Identities = 283/988 (28%), Positives = 395/988 (39%), Gaps = 189/988 (19%)
Query: 247 PGLSKQEDCCGTVG------------TSWG-FNKCQKCPKKPSYHGYNQMME-------- 285
P + +C T G TS G N +C + P+ + Q ++
Sbjct: 1816 PVCQRNAECINTAGSYRCDCKPGYRFTSTGQCNDRNECQEIPNICSHGQCIDTVGSFYCL 1875
Query: 286 CLPGYKRVNN-TFCQDINECQLQGVCPNGECLNTMGSYRCTCKIGFGPDPTFSSCVPDPP 344
C G+K ++ T C DINEC+ + C NG C NT+GS+ C C GF + C+
Sbjct: 1876 CHTGFKTNDDQTMCLDINECE-RDACGNGTCRNTIGSFNCRCNHGFILSHN-NDCIDVDE 1933
Query: 345 VISEEKGPC-------------------YRLVSSGRQCMHPLSVHLTKQLCC-------- 377
S C Y + GR C+ L + C
Sbjct: 1934 CASGNGNLCRNGQCINTVGSFQCQCNEGYEVAPDGRTCVDINECLLEPRKCAPGTCQNLD 1993
Query: 378 ----CSVGKAWGPHCEKCP------------LPGT-----AAFKEICPGGMGYTVSGVHR 416
C + EKC GT +FK +CP G + SG R
Sbjct: 1994 GSYRCICPPGYSLQNEKCEDIDECVEEPEICALGTCSNTEGSFKCLCPEGFSLSSSG--R 2051
Query: 417 RRPIHHHVGKGPVFVKPKNTQPVAKSTHPPPLPAKEEPVEALTFSREHGPGVAEP-EVAT 475
R F K + P +++ +K+E AL G G +P E+
Sbjct: 2052 RCQDLRMSYCYAKFEGGKCSSPKSRN------HSKQECCCAL-----KGEGWGDPCELCP 2100
Query: 476 APPEKEIPSLDQEKTKLEPGQPQLSPGISTIHLHPQFPGIVIEKTSPPVPVEVAPEASTS 535
P++ Q+ P S I + P + +++ P + +T
Sbjct: 2101 TEPDEAF--------------RQICPYGSGIIVGPDDSAVDMDECKEPDVCKHGQCINTD 2146
Query: 536 SASQVIAPTQVTEINECTVNPDIC------GAGHCINLPVRYTCICYEGYRFSEQQRKCV 589
+ + P V+ D C G G C N+ + C C EG+ C
Sbjct: 2147 GSYRCECPFGYILAGNECVDTDECSVGNPCGNGTCKNVIGGFECTCEEGFE-PGPMMTCE 2205
Query: 590 DIDECTQVQHLCSQGRCENTEGSFLCICPAGFMASEEGTNCIDVDECLR-PDVCGEG--H 646
DI+EC Q LC+ RC NT GS+ C CP G++ E+ C D DEC C E
Sbjct: 2206 DINECAQNPLLCA-FRCVNTYGSYECKCPVGYVLREDRRMCKDEDECEEGKHDCTEKQME 2264
Query: 647 CVNTVGAFRCEYCDSGYRMTQRGR-CEDIDEC-LNPSTCPDEQCVNSPGSYQCVPCTEGF 704
C N +G + C C GY+ G C D +EC P C + +C+N+ GSY C C +GF
Sbjct: 2265 CKNLIGTYMC-ICGPGYQRRPDGEGCVDENECQTKPGICENGRCLNTRGSYTC-ECNDGF 2322
Query: 705 RGWNGQCLDVDECLE-----------PNVCANGDCS-NLEGSYMCSCHKGYTRTPDHKHC 752
Q DECL+ N+C G + N C C G P + C
Sbjct: 2323 TASPNQ----DECLDNREGYCFTEVLQNMCQIGSSNRNPVTKSECCCDGGRGWGPHCEIC 2378
Query: 753 ----------------------RDIDECQQ-GNLCVNGQCKNTEGSFRCTCGQGYQLSAA 789
DIDEC+ ++C NG+C N GS+ C C GY
Sbjct: 2379 PFQGTVAFKKLCPHGRGFMTNGADIDECKVIHDVCRNGECVNDRGSYHCICKTGYTPDIT 2438
Query: 790 KDQCEDIDECQHRHLCAHGQCRNTEGSFQCVCDQGYRASGLGDHCEDINECLEDKSVCQR 849
C D++EC + C+NTEGS+QC C +GY G C+D++EC + CQ
Sbjct: 2439 GTSCVDLNECNQAPKPCNFICKNTEGSYQCSCPKGYILQEDGRSCKDLDECATKQHNCQ- 2497
Query: 850 GDCINTAGSYDCTCPDGFQLDDNKTCQDINECEHP-GLCGPQGECLNTEGSFHCVCQQGF 908
C+NT G + C CP GF + +C D NEC LCG +G C NT GSF C CQ+GF
Sbjct: 2498 FLCVNTIGGFTCKCPPGF-TQHHTSCIDNNECTSDINLCGSKGICQNTPGSFTCECQRGF 2556
Query: 909 SISADGRTCEDIDECVNNTVCDSHGFCDNTAGSFRCLCYQGFQAPQDGQGCVDVNECELL 968
S+ G +CED+DEC N C HG C N G +RC C QG+ CVD NEC L
Sbjct: 2557 SLDQTGSSCEDVDECEGNHRC-QHG-CQNIIGGYRCSCPQGYLQHYQWNQCVDENEC-LS 2613
Query: 969 SGVCGEAFCENVEGSFLCVCADENQEYSPMTGQCRSRTSTDLDVDVDQPKEEKKECYY-- 1026
+ +CG A C N GS+ C+C +Y +G C+ D+++ + C Y
Sbjct: 2614 AHICGGASCHNTLGSYKCMC-PAGFQYEQFSGGCQ---------DINECGSAQAPCSYGC 2663
Query: 1027 -NLNDASLCDNVLAPNVTK-QECCCTSGAGWG-DNCEIFPCPVLGTAEFTEMCP------ 1077
N LC P + + C SG G G N E PV G + + P
Sbjct: 2664 SNTEGGYLCG--CPPGYFRIGQGHCVSGMGMGRGNPE---PPVSGEMDDNSLSPEACYEC 2718
Query: 1078 KGKGFVPAG---ESSSEAGGENYKDADE 1102
K G+ G S++E N +D E
Sbjct: 2719 KINGYPKRGRKRRSTNETDASNIEDQSE 2746
Score = 203 bits (517), Expect = 8e-52
Identities = 213/810 (26%), Positives = 303/810 (37%), Gaps = 196/810 (24%)
Query: 690 NSPGSYQCVPCTEGFRGWNGQCLDVDECLEP---NVCANGDCSNLEGSYMCSCHKGY--- 743
N GS C G++ G ++C+ P + C +G CS MC+C G
Sbjct: 57 NVCGSRYNAYCCPGWKTLPGG----NQCIVPICRHSCGDGFCSRPN---MCTCPSGQIAP 109
Query: 744 ---TRTPDHKHCRDIDECQQGNLCVNGQCKNTEGSFRCTCGQGYQLSAAKDQCEDIDECQ 800
+R+ H + R C G C + C +G CGQ + C + C
Sbjct: 110 SCGSRSIQHCNIR----CMNGGSCSDDHCLCQKGYIGTHCGQ----PVCESGCLNGGRC- 160
Query: 801 HRHLCAHGQCRNTEGSFQCVCDQGYRASGLGDHCEDINECLEDKS--VCQRGDCINTAG- 857
A +C T G C++ YR + C S VC + C T G
Sbjct: 161 ----VAPNRCACTYGFTGPQCERDYRTGPCFTVISN-QMCQGQLSGIVCTKTLCCATVGR 215
Query: 858 --SYDCT--------CPDGFQLDDNKT--CQDINECEH-PGLCGPQGECLNTEGSFHCVC 904
+ C C GF + + +T CQD++EC+ PGLC G C+NT GSF C C
Sbjct: 216 AWGHPCEMCPAQPHPCRRGF-IPNIRTGACQDVDECQAIPGLC-QGGNCINTVGSFECKC 273
Query: 905 QQGFSISADGRTCEDIDECVNNTVCDSHGFCDNTAGSFRCLCYQGFQAPQDGQGCVDVNE 964
G ++ + CEDIDEC G C NT S+ C C GF DG C+DV
Sbjct: 274 PAGHKLNEVSQKCEDIDECSTIPGICEGGECTNTVSSYFCKCPPGFYTSPDGTRCIDVRP 333
Query: 965 ----CELLSGVCGEAFCENVEGSFLCVCADENQEYSP----MTGQCRSRTSTDLD----- 1011
L +G C +++ + + C D + +SP C R + D +
Sbjct: 334 GYCYTALTNGRCSNQLPQSI--TKMQCCCDAGRCWSPGVTVAPEMCPIRATEDFNKLCSV 391
Query: 1012 ---------------------------------VDVDQP--------KEEKKECYYNLND 1030
+ V +P +E + N+ D
Sbjct: 392 PMVIPGRPEYPPPPLGPIPPVLPVPPGFPPGPQIPVPRPPVEYLYPSREPPRVLPVNVTD 451
Query: 1031 ASLCDNVLAPN----VTKQECCCTSGAGWG----------DNCEIFPCP----VLGTAEF 1072
L N T C C G+ D CE PC + +
Sbjct: 452 YCQLVRYLCQNGRCIPTPGSCRCECNKGFQLDLRGECIDVDECEKNPCAGGECINNQGSY 511
Query: 1073 TEMCPKGKGFVPAGESSSEAGGENYKDADECLLFGQEICKNGFCLNTRPGYECYCKQGTY 1132
T C G S +D DECL G+ IC NG C+NT + C C G +
Sbjct: 512 TCQCRAG--------YQSTLTRTECRDIDECLQNGR-ICNNGRCINTDGSFHCVCNAGFH 562
Query: 1133 YDPVKLQCFDMDECQDPSSCIDGQCVNTEGSYNCFCTHPMVLDASEKRC--IRPAES--- 1187
C DMDEC + C++G C+N +GS+ C C L + + C I E+
Sbjct: 563 VTRDGKNCEDMDECSIRNMCLNGMCINEDGSFKCICKPGFQLASDGRYCKDINECETPGI 622
Query: 1188 --NEQIEETD-VYQDLCWEHLS---------DEYV------------CSRPLVGKQTTYT 1223
N + TD Y+ C+ L+ D ++ C +PL G T +
Sbjct: 623 CMNGRCVNTDGSYRCECFPGLAVGLDGRVCVDTHMRSTCYGGYKRGQCIKPLFG-AVTKS 681
Query: 1224 ECCCLYGE-AWGMQCALCPLKDSDDYAQLCNIPVTGRRQPYGRDALVDFSEQYTPEADPY 1282
ECCC E A+G C CP ++S +Y LC+ P A D +E DP
Sbjct: 682 ECCCASTEYAFGEPCQPCPAQNSAEYQALCS------SGPGMTSAGSDINE---CALDP- 731
Query: 1283 FIQDRFLNSFEELQAEECGILNGCENGRCVRVQEGYTCDCFDGYHLDTAKMTCVDVNECD 1342
+ C NG C ++ Y C C GY +D+ CVD+NEC
Sbjct: 732 ---------------------DICPNGICENLRGTYKCICNSGYEVDSTGKNCVDINEC- 769
Query: 1343 ELNNRMSLCKNAKCINTDGSYKCLCLPGYV 1372
LN+ LC N +C NT GS+ C C G++
Sbjct: 770 VLNS--LLCDNGQCRNTPGSFVCTCPKGFI 797
Score = 149 bits (375), Expect = 2e-35
Identities = 143/557 (25%), Positives = 213/557 (38%), Gaps = 151/557 (27%)
Query: 861 CTCPDGFQLDDNKTCQDINECEHPGLCGPQGECLNTEGSFHCVCQQGFSISADGR-TCED 919
CTCP G Q+ + + I C + G G C + HC+CQ+G+ + G+ CE
Sbjct: 100 CTCPSG-QIAPSCGSRSIQHCNIRCMNG--GSCSDD----HCLCQKGYIGTHCGQPVCES 152
Query: 920 IDECVNNTVCDSHGFCDNTAGSFRCLCYQGFQAPQDGQGCVDVNECELLSGVCGEAFCEN 979
C+N C + RC C GF PQ CE
Sbjct: 153 --GCLNGGRCVAPN---------RCACTYGFTGPQ----------------------CE- 178
Query: 980 VEGSFLCVCADENQEYSPMTGQCRSRTSTDLDVDVDQPKEEKKECYYNLNDASLCDNVLA 1039
++Y TG C + + +C L+
Sbjct: 179 -------------RDYR--TGPC-----------------------FTVISNQMCQGQLS 200
Query: 1040 PNV-TKQECCCTSGAGWGDNCEIFPCPVLGTAEFTEMCPKGKGFVPAGESSSEAGGENYK 1098
V TK CC T G WG CE+ P + P +GF+P + + +
Sbjct: 201 GIVCTKTLCCATVGRAWGHPCEMCPA---------QPHPCRRGFIPNIRTGA------CQ 245
Query: 1099 DADECLLFGQEICKNGFCLNTRPGYECYCKQGTYYDPVKLQCFDMDECQD-PSSCIDGQC 1157
D DEC +C+ G C+NT +EC C G + V +C D+DEC P C G+C
Sbjct: 246 DVDECQAI-PGLCQGGNCINTVGSFECKCPAGHKLNEVSQKCEDIDECSTIPGICEGGEC 304
Query: 1158 VNTEGSYNCFCTHPMVLDASEKRCIRPAESNEQIEETDVYQDLCWEHLSDEYVCSRPLVG 1217
NT SY C C RCI DV C+ L++ CS L
Sbjct: 305 TNTVSSYFCKCPPGFYTSPDGTRCI------------DVRPGYCYTALTNGR-CSNQL-P 350
Query: 1218 KQTTYTECCCLYGEAW--GMQCA--LCPLKDSDDYAQLCNIP--VTGRRQ---------- 1261
+ T +CCC G W G+ A +CP++ ++D+ +LC++P + GR +
Sbjct: 351 QSITKMQCCCDAGRCWSPGVTVAPEMCPIRATEDFNKLCSVPMVIPGRPEYPPPPLGPIP 410
Query: 1262 ---------PYGRDALVDFS--EQYTPEADPYFIQDRFLNSFEELQAEECGILNGCENGR 1310
P G V E P +P + + + +L + C+NGR
Sbjct: 411 PVLPVPPGFPPGPQIPVPRPPVEYLYPSREPPRVLPVNVTDYCQL------VRYLCQNGR 464
Query: 1311 CVRVQEGYTCDCFDGYHLDTAKMTCVDVNECDELNNRMSLCKNAKCINTDGSYKCLCLPG 1370
C+ C+C G+ LD + C+DV+EC++ + C +CIN GSY C C G
Sbjct: 465 CIPTPGSCRCECNKGFQLD-LRGECIDVDECEK-----NPCAGGECINNQGSYTCQCRAG 518
Query: 1371 YVPSDKPNYCTPLNTAL 1387
Y + C ++ L
Sbjct: 519 YQSTLTRTECRDIDECL 535
Score = 125 bits (315), Expect = 2e-28
Identities = 66/216 (30%), Positives = 102/216 (47%), Gaps = 19/216 (8%)
Query: 213 SHQQVIPHVYPVAAKTQLGRCFQETIGSQCGKALPGLSKQEDCCGTVGTSWGFNKCQKCP 272
S + + + +T G C+Q I +C + G + + CC ++G +WG + C C
Sbjct: 833 SSESTLDPTKTICIETIKGTCWQTVIDGRCEININGATLKSQCCSSLGAAWG-SPCTLCQ 891
Query: 273 KKPSYHGYNQMMECLPGYKRVNNTFCQDINECQL-QGVCPNGECLNTMGSYRCTCKIGFG 331
P C GY R+ T C+DI+EC++ GVC NG C+NT GS++C C G
Sbjct: 892 VDPI---------CGKGYSRIKGTQCEDIDECEVFPGVCKNGLCVNTRGSFKCQCPSGMT 942
Query: 332 PDPTFSSCVPDPPVISEEKGPCYRLVSSGRQCMHPLSVHLTKQLCCCSVGKAWG-PHCEK 390
D T C + C+ L +C P++ CCCSVG AWG CE+
Sbjct: 943 LDATGRIC------LDIRLETCF-LRYEDEECTLPIAGRHRMDACCCSVGAAWGTEECEE 995
Query: 391 CPLPGTAAFKEICPGGMGYTVSGVHRRRPIHHHVGK 426
CP+ T ++E+CP G G+ + +P + +
Sbjct: 996 CPMRNTPEYEELCPRGPGFATKEITNGKPFFKDINE 1031
Score = 120 bits (300), Expect = 1e-26
Identities = 101/375 (26%), Positives = 138/375 (36%), Gaps = 90/375 (24%)
Query: 556 PDICGAGHCINLPVRYTCICYEGYRFSEQQRKCVDIDECTQVQHLCSQGRCENTEGSFLC 615
P++CG+ RY C G++ +C+ + C +H C G C +C
Sbjct: 56 PNVCGS--------RYNAYCCPGWKTLPGGNQCI-VPIC---RHSCGDGFCSRPN---MC 100
Query: 616 ICPAGFMASEEGTNCIDVDE--CLRPDVCGEGHCVNTVGAFRCEYCDSGYRMTQRGRCED 673
CP+G +A G+ I C+ C + HC+ C GY T G+
Sbjct: 101 TCPSGQIAPSCGSRSIQHCNIRCMNGGSCSDDHCL----------CQKGYIGTHCGQPVC 150
Query: 674 IDECLNPSTC-PDEQCVNSPGSYQCVPCTEGFRGWNGQCLDVDECLEPNVCANGDCSNLE 732
CLN C +C CT GF G QC G C +
Sbjct: 151 ESGCLNGGRCVAPNRCA----------CTYGFTG--PQC--------ERDYRTGPCFTVI 190
Query: 733 GSYMCSCHKGYTRTPDHKHCRDIDECQQGNLCVNGQCKNTEG---SFRCT--------CG 781
+ MC G +C C T G C C
Sbjct: 191 SNQMCQGQLS------------------GIVCTKTLCCATVGRAWGHPCEMCPAQPHPCR 232
Query: 782 QGYQLSAAKDQCEDIDECQH-RHLCAHGQCRNTEGSFQCVCDQGYRASGLGDHCEDINEC 840
+G+ + C+D+DECQ LC G C NT GSF+C C G++ + + CEDI+EC
Sbjct: 233 RGFIPNIRTGACQDVDECQAIPGLCQGGNCINTVGSFECKCPAGHKLNEVSQKCEDIDEC 292
Query: 841 LEDKSVCQRGDCINTAGSYDCTCPDGFQLD-DNKTCQDINECEHPGLCG---PQGECLN- 895
+C+ G+C NT SY C CP GF D C D+ PG C G C N
Sbjct: 293 STIPGICEGGECTNTVSSYFCKCPPGFYTSPDGTRCIDV----RPGYCYTALTNGRCSNQ 348
Query: 896 ---TEGSFHCVCQQG 907
+ C C G
Sbjct: 349 LPQSITKMQCCCDAG 363
Score = 97.4 bits (241), Expect = 8e-20
Identities = 51/131 (38%), Positives = 67/131 (51%), Gaps = 12/131 (9%)
Query: 285 ECLPGYKRVNNTF-CQDINECQLQGVCPNGECLNTMGSYRCTCKIGFGPDPTFSSCVPDP 343
EC GY+ + C D+NEC C +G C+NT GSY C C F +PT CV
Sbjct: 1471 ECEIGYELDRSGGNCTDVNECLDPTTCISGNCVNTPGSYICDCPPDFELNPTRVGCV--- 1527
Query: 344 PVISEEKGPCY-----RLVSSGRQCMHPLSVHLTKQLCCCSVGKAWGPHCEKCPLPGTAA 398
G CY R + C + + V ++K CCCS+GKAWG CE CP T+
Sbjct: 1528 ---DTRSGNCYLDIRPRGDNGDTACSNEIGVGVSKASCCCSLGKAWGTPCEMCPAVNTSE 1584
Query: 399 FKEICPGGMGY 409
+K +CPGG G+
Sbjct: 1585 YKILCPGGEGF 1595
Score = 89.7 bits (221), Expect = 2e-17
Identities = 51/161 (31%), Positives = 75/161 (46%), Gaps = 28/161 (17%)
Query: 246 LPGLSKQEDCCGTVGTSWGFNKCQKCPKKPSYHGYNQMMECLPGYKRVNNTFCQDINECQ 305
LPGL + C T G+ +C +CP GY Y + C D+NEC+
Sbjct: 1613 LPGLCQGGKCINTFGSF----QC-RCPT-----GY---------YLNEDTRVCDDVNECE 1653
Query: 306 LQGVCPNGECLNTMGSYRCTCKIGFGPDPTFSSCVPDPPVISEEKGPCYR-LVSSGRQCM 364
G+C G C NT+G+Y C C P + + + CYR + + C
Sbjct: 1654 TPGICGPGTCYNTVGNYTCIC------PPDYMQVNGGNNCMDMRRSLCYRNYYADNQTCD 1707
Query: 365 HPLSVHLTKQLCCCS--VGKAWGPHCEKCPLPGTAAFKEIC 403
L ++TK++CCCS +G+AW CE+CP+P T F +C
Sbjct: 1708 GELLFNMTKKMCCCSYNIGRAWNKPCEQCPIPSTDEFATLC 1748
Score = 86.7 bits (213), Expect = 1e-16
Identities = 61/196 (31%), Positives = 84/196 (42%), Gaps = 34/196 (17%)
Query: 241 QCGKALPGLSKQEDCCGTVG-----------------TSWGFNKCQKCPKKPSYHGYNQM 283
+C L + C TVG T N+C P+K + G Q
Sbjct: 1933 ECASGNGNLCRNGQCINTVGSFQCQCNEGYEVAPDGRTCVDINECLLEPRKCA-PGTCQN 1991
Query: 284 ME------CLPGYKRVNNTFCQDINEC-QLQGVCPNGECLNTMGSYRCTCKIGFGPDPTF 336
++ C PGY + N C+DI+EC + +C G C NT GS++C C GF +
Sbjct: 1992 LDGSYRCICPPGYS-LQNEKCEDIDECVEEPEICALGTCSNTEGSFKCLCPEGFSLSSSG 2050
Query: 337 SSCVPDPPVISEEKGPCYRLVSSGRQCMHPLSVHLTKQLCCCSV-GKAWGPHCEKCPLPG 395
C CY G+ C P S + +KQ CCC++ G+ WG CE CP
Sbjct: 2051 RRCQ------DLRMSYCYAKFEGGK-CSSPKSRNHSKQECCCALKGEGWGDPCELCPTEP 2103
Query: 396 TAAFKEICPGGMGYTV 411
AF++ICP G G V
Sbjct: 2104 DEAFRQICPYGSGIIV 2119
Score = 78.2 bits (191), Expect = 5e-14
Identities = 38/116 (32%), Positives = 64/116 (55%), Gaps = 6/116 (5%)
Query: 229 QLGRCFQETIGSQCGKALPGLSKQEDCCGTVGTSWGFNKCQKCPKKPSYHGYNQMMECLP 288
+L CF +C + G + + CC +VG +WG +C++CP + + Y ++ P
Sbjct: 954 RLETCFLRYEDEECTLPIAGRHRMDACCCSVGAAWGTEECEECPMRNTPE-YEELCPRGP 1012
Query: 289 GY--KRVNN--TFCQDINECQ-LQGVCPNGECLNTMGSYRCTCKIGFGPDPTFSSC 339
G+ K + N F +DINEC+ + +C +G+C NT+GS++C C GF D +C
Sbjct: 1013 GFATKEITNGKPFFKDINECKMIPSLCTHGKCRNTIGSFKCRCDSGFALDSEERNC 1068
Score = 72.0 bits (175), Expect = 4e-12
Identities = 65/199 (32%), Positives = 85/199 (42%), Gaps = 39/199 (19%)
Query: 231 GRCFQETIGSQC--GKALPGLSKQEDCCGTVGTSWGFNKCQKCPKKPSYHGYNQMMECLP 288
G CF E + + C G + + +CC G WG + C+ CP + G + P
Sbjct: 2337 GYCFTEVLQNMCQIGSSNRNPVTKSECCCDGGRGWGPH-CEICP----FQGTVAFKKLCP 2391
Query: 289 GYKRVNNTFCQDINECQ-LQGVCPNGECLNTMGSYRCTCKIGFGPDPTFSSCVPDPPVIS 347
+ R T DI+EC+ + VC NGEC+N GSY C CK G+ PD T +SCV D +
Sbjct: 2392 -HGRGFMTNGADIDECKVIHDVCRNGECVNDRGSYHCICKTGYTPDITGTSCV-DLNECN 2449
Query: 348 EEKGPC------------------YRLVSSGRQCMHPLSVHLTKQ-----LCCCSVGKAW 384
+ PC Y L GR C L TKQ LC ++G
Sbjct: 2450 QAPKPCNFICKNTEGSYQCSCPKGYILQEDGRSC-KDLDECATKQHNCQFLCVNTIG--- 2505
Query: 385 GPHCEKCPLPGTAAFKEIC 403
G C KCP PG C
Sbjct: 2506 GFTC-KCP-PGFTQHHTSC 2522
Score = 68.9 bits (167), Expect = 3e-11
Identities = 39/102 (38%), Positives = 52/102 (50%), Gaps = 10/102 (9%)
Query: 1293 EELQAEECGILNGCENGRCVRVQEGYTCDCFDGYHLDTAKMTCVDVNECDELNNRMSLCK 1352
E + +EC N C G C+ Q YTC C GY + C D++EC + N R +C
Sbjct: 487 ECIDVDECE-KNPCAGGECINNQGSYTCQCRAGYQSTLTRTECRDIDECLQ-NGR--ICN 542
Query: 1353 NAKCINTDGSYKCLCLPGY-VPSDKPN-----YCTPLNTALN 1388
N +CINTDGS+ C+C G+ V D N C+ N LN
Sbjct: 543 NGRCINTDGSFHCVCNAGFHVTRDGKNCEDMDECSIRNMCLN 584
Score = 66.6 bits (161), Expect = 2e-10
Identities = 34/103 (33%), Positives = 52/103 (50%), Gaps = 3/103 (2%)
Query: 229 QLGRCFQETIGSQCGKALP-GLSKQEDCCGTVGTSWGFNKCQKCPKKPSYHGYNQMMECL 287
++ C+ + G +C SKQE CC G WG + C+ CP +P + Q+
Sbjct: 2057 RMSYCYAKFEGGKCSSPKSRNHSKQECCCALKGEGWG-DPCELCPTEPD-EAFRQICPYG 2114
Query: 288 PGYKRVNNTFCQDINECQLQGVCPNGECLNTMGSYRCTCKIGF 330
G + D++EC+ VC +G+C+NT GSYRC C G+
Sbjct: 2115 SGIIVGPDDSAVDMDECKEPDVCKHGQCINTDGSYRCECPFGY 2157
Score = 57.0 bits (136), Expect = 1e-07
Identities = 36/90 (40%), Positives = 46/90 (51%), Gaps = 15/90 (16%)
Query: 307 QGVCPNGECLN---TMGSYRCTCKIGFGPDPTFSSCVPDPPVISEEKGPCYRLVSSGRQC 363
Q VC +G CLN + RC C GF T C D GPC+ ++S+ + C
Sbjct: 147 QPVCESG-CLNGGRCVAPNRCACTYGF----TGPQCERD-----YRTGPCFTVISN-QMC 195
Query: 364 MHPLS-VHLTKQLCCCSVGKAWGPHCEKCP 392
LS + TK LCC +VG+AWG CE CP
Sbjct: 196 QGQLSGIVCTKTLCCATVGRAWGHPCEMCP 225
Score = 55.5 bits (132), Expect = 4e-07
Identities = 30/91 (32%), Positives = 48/91 (52%), Gaps = 4/91 (4%)
Query: 243 GKALPGLSKQEDCCG-TVGTSWGFNKCQKCPKKPSYHGYNQMMECLPGYK-RVNNTFCQD 300
G+ L ++K+ CC +G +W C++CP + PG+ + D
Sbjct: 1708 GELLFNMTKKMCCCSYNIGRAWN-KPCEQCPIPSTDEFATLCGSQRPGFVIDIYTGLPVD 1766
Query: 301 INEC-QLQGVCPNGECLNTMGSYRCTCKIGF 330
I+EC ++ GVC NG C+N +GS+RC C +GF
Sbjct: 1767 IDECREIPGVCENGVCINMVGSFRCECPVGF 1797
Score = 49.3 bits (116), Expect = 3e-05
Identities = 21/34 (61%), Positives = 25/34 (73%), Gaps = 1/34 (2%)
Query: 298 CQDINECQLQGVCP-NGECLNTMGSYRCTCKIGF 330
C+DI+ECQ VC N EC+NT GSYRC CK G+
Sbjct: 1806 CEDIDECQNGPVCQRNAECINTAGSYRCDCKPGY 1839
Score = 45.4 bits (106), Expect = 4e-04
Identities = 40/161 (24%), Positives = 57/161 (35%), Gaps = 11/161 (6%)
Query: 231 GRCFQETIGSQCGKALPGLSKQEDCCGTVGTSWGFNKCQKCPKKPSYHGYNQMMECLPGY 290
G+C +C + +C T S G N C K G+ C G+
Sbjct: 2140 GQCINTDGSYRCECPFGYILAGNECVDTDECSVG-NPCGNGTCKNVIGGFE--CTCEEGF 2196
Query: 291 KRVNNTFCQDINECQLQGVCPNGECLNTMGSYRCTCKIGFGPDPTFSSCVPDPPVISEEK 350
+ C+DINEC + C+NT GSY C C +G+ C D E K
Sbjct: 2197 EPGPMMTCEDINECAQNPLLCAFRCVNTYGSYECKCPVGYVLREDRRMC-KDEDECEEGK 2255
Query: 351 GPCYRLVSSGRQCMHPLSVHLTKQLCCCSVGKAWGPHCEKC 391
C +C + + + +C C G P E C
Sbjct: 2256 HDC---TEKQMECKNLIGTY----MCICGPGYQRRPDGEGC 2289
Score = 45.4 bits (106), Expect = 4e-04
Identities = 37/127 (29%), Positives = 49/127 (38%), Gaps = 17/127 (13%)
Query: 235 QETIGSQCGKALPGLSKQE--DCCGTVGTSWGFNKCQKCPKKPSYHGYNQMM-----ECL 287
Q T GS + G S + C V G ++CQ HG ++ C
Sbjct: 2542 QNTPGSFTCECQRGFSLDQTGSSCEDVDECEGNHRCQ--------HGCQNIIGGYRCSCP 2593
Query: 288 PGY-KRVNNTFCQDINECQLQGVCPNGECLNTMGSYRCTCKIGFGPDPTFSSCVPDPPVI 346
GY + C D NEC +C C NT+GSY+C C GF + FS D
Sbjct: 2594 QGYLQHYQWNQCVDENECLSAHICGGASCHNTLGSYKCMCPAGFQYE-QFSGGCQDINEC 2652
Query: 347 SEEKGPC 353
+ PC
Sbjct: 2653 GSAQAPC 2659
Score = 41.2 bits (95), Expect = 0.007
Identities = 17/43 (39%), Positives = 24/43 (55%), Gaps = 1/43 (2%)
Query: 298 CQDINECQLQ-GVCPNGECLNTMGSYRCTCKIGFGPDPTFSSC 339
C D+NEC L +C +G C NT GS+ C C +G+ + C
Sbjct: 1278 CVDVNECDLNPNICLSGTCENTKGSFICHCDMGYSGKKGKTGC 1320
Score = 39.3 bits (90), Expect = 0.027
Identities = 21/75 (28%), Positives = 32/75 (42%), Gaps = 19/75 (25%)
Query: 35 CKVTCTKG-SCQNS---CEKGNTTTLISENGHAADTLTATNFRVVICHLPCMNGGQCSSR 90
C + C G SC + C+KG T + +C C+NGG+C +
Sbjct: 119 CNIRCMNGGSCSDDHCLCQKGYIGTHCGQP---------------VCESGCLNGGRCVAP 163
Query: 91 DKCQCPPNFTGKLCQ 105
++C C FTG C+
Sbjct: 164 NRCACTYGFTGPQCE 178
Score = 37.4 bits (85), Expect = 0.10
Identities = 18/48 (37%), Positives = 26/48 (54%), Gaps = 3/48 (6%)
Query: 286 CLPGYK-RVNNTFCQDINECQL--QGVCPNGECLNTMGSYRCTCKIGF 330
C GY + T C DINEC++ + C NT GS++C+C G+
Sbjct: 1307 CDMGYSGKKGKTGCTDINECEIGAHNCGKHAVCTNTAGSFKCSCSPGW 1354
Score = 35.8 bits (81), Expect = 0.30
Identities = 25/73 (34%), Positives = 33/73 (45%), Gaps = 12/73 (16%)
Query: 32 PSICKVTC--TKGSCQNSCEKGNTTTLISENGHAADTLTATNFRVVICHLPCMN--GGQC 87
P C C T+GS Q SC KG ++ E+G + L + C C+N GG
Sbjct: 2452 PKPCNFICKNTEGSYQCSCPKGY---ILQEDGRSCKDLDECATKQHNCQFLCVNTIGGFT 2508
Query: 88 SSRDKCQCPPNFT 100
C+CPP FT
Sbjct: 2509 -----CKCPPGFT 2516
>gi|56237021 fibrillin 3 precursor [Homo sapiens]
Length = 2809
Score = 517 bits (1331), Expect = e-146
Identities = 310/890 (34%), Positives = 424/890 (47%), Gaps = 146/890 (16%)
Query: 548 EINECTVNPDICGAGHCINLPVRYTCICYEGYRFSEQQRKCVDIDECTQVQHLCSQGRCE 607
++NEC V P +C G C N + C C G+ Q+R C DIDEC LC QG C
Sbjct: 986 DVNECKVFPGLCTHGTCRNTVGSFHCACAGGFALDAQERNCTDIDECRISPDLCGQGTCV 1045
Query: 608 NTEGSFLCIC----PAGFMASEEGTNCIDVDECLR-PDVCGEGHCVNTVGAFRCEYCDSG 662
NT GSF C C +GFM + NC+DVDEC R P +C G C NT G+++C+ C G
Sbjct: 1046 NTPGSFECECFPGYESGFMLMK---NCMDVDECARDPLLCRGGTCTNTDGSYKCQ-CPPG 1101
Query: 663 YRMTQRG-RCEDIDEC-LNPSTCPDEQCVNSPGSYQCVPCTEGFRGWNGQ--CLDVDECL 718
+ +T +G CEDIDEC L+ CP QCVN G++QC C GF+ + C+D++EC
Sbjct: 1102 HELTAKGTACEDIDECSLSDGLCPHGQCVNVIGAFQC-SCHAGFQSTPDRQGCVDINECR 1160
Query: 719 EPNVCANGDCSNLEGSYMCSCHKGYTRTPDHKHCRDIDECQQG-NLCVNGQCKNTEGSFR 777
N + C N EGSY CSC +GY+ PD + C D+DEC++ +C G C N G R
Sbjct: 1161 VQNGGCDVHCINTEGSYRCSCGQGYSLMPDGRACADVDECEENPRVCDQGHCTNMPGGHR 1220
Query: 778 CTCGQGYQLSAAKDQCEDIDECQ-HRHLCAHGQCRNTEGSFQCVCDQGYR----ASGLGD 832
C C G+ + C D+DEC + H+C HG C NT+GSF C C GY A+G D
Sbjct: 1221 CLCYDGFMATPDMRTCVDVDECDLNPHICLHGDCENTKGSFVCHCQLGYMVRKGATGCSD 1280
Query: 833 -------------------------------------HCEDINECLEDKSVCQ-RGDCIN 854
C D++EC+ + C RGDC+N
Sbjct: 1281 VDECEVGGHNCDSHASCLNIPGSFSCRCLPGWVGDGFECHDLDECVSQEHRCSPRGDCLN 1340
Query: 855 TAGSYDCTCPDGFQLDDNKTCQDINEC-EHPGLCGPQGECLNTEGSFHCVCQQGFSISAD 913
GSY CTC GF D C+D +EC E+ LC G+CLN G + C C+ GF + D
Sbjct: 1341 VPGSYRCTCRQGF-AGDGFFCEDRDECAENVDLC-DNGQCLNAPGGYRCECEMGFDPTED 1398
Query: 914 GRTCEDIDECVNNTVCDSHGFCDNTAGSFRCLCYQGFQAPQDGQGCVDVNECELLSGVCG 973
R C+D+DEC +C + G C+N G FRC+C G++ + G C D+NEC C
Sbjct: 1399 HRACQDVDECAQGNLC-AFGSCENLPGMFRCICNGGYELDRGGGNCTDINECADPVN-CI 1456
Query: 974 EAFCENVEGSFLCVCADENQEYSPMTGQCRSRTSTDLDVDVDQPKEEKKECYYNLNDAS- 1032
C N GS+LC C ++ E +P C VD C+ +D
Sbjct: 1457 NGVCINTPGSYLCSC-PQDFELNPSGVGC---------VDT-----RAGNCFLETHDRGD 1501
Query: 1033 ---LCDNVLAPNVTKQECCCTSGAGWGDNCEIFPCPVLGTAEFTEMCPKGKGFVPAGESS 1089
C + VT+ CCC+ G WG+ CE+ CP+ T E+ +CP G+GF P +
Sbjct: 1502 SGISCSAEIGVGVTRASCCCSLGRAWGNPCEL--CPMANTTEYRTLCPGGEGFQPNRITV 1559
Query: 1090 SEAGGENYKDADECLLFGQE---ICKNGFCLNTRPGYECYCKQGTYYDPVKLQCFDMDEC 1146
+D DEC QE +C+ G C+NT ++C C G + C D+DEC
Sbjct: 1560 I------LEDIDEC----QELPGLCQGGDCVNTFGSFQCECPPGYHLSEHTRICEDIDEC 1609
Query: 1147 QDPSS-CIDGQCVNTEGSYNCFCTHPMVLDASEKRCIRPAESNEQIEETDVYQDLCWEHL 1205
S C G C NT G+Y C C + C+ D+ + +C+ H
Sbjct: 1610 STHSGICGPGTCYNTLGNYTCVCPAEYLQVNGGNNCM------------DMRKSVCFRHY 1657
Query: 1206 SDEYVCSRPLVGKQTTYTECCCLY--GEAWGMQCALCPLKDSDDYAQLCNIPVTGRRQPY 1263
+ C L T CCC Y G+AW C CP S DY LC
Sbjct: 1658 NG--TCQNEL-AFNVTRKMCCCSYNIGQAWNRPCEACPTPISPDYQILC----------- 1703
Query: 1264 GRDALVDFSEQYTPEADPYFIQDRFLNSFEELQAEECGILNG-CENGRCVRVQEGYTCDC 1322
G A P F+ D +++ + L +ECG + C NG C+ + C+C
Sbjct: 1704 GNQA-------------PGFLTD--IHTGKPLDIDECGEIPAICANGICINQIGSFRCEC 1748
Query: 1323 FDGYHLDTAKMTCVDVNECDELNNRMSLC-KNAKCINTDGSYKCLCLPGY 1371
G++ ++ + C DV+EC +R S C +NA CIN GSY+C C GY
Sbjct: 1749 PAGFNYNSILLACEDVDEC---GSRESPCQQNADCINIPGSYRCKCTRGY 1795
Score = 463 bits (1192), Expect = e-130
Identities = 361/1221 (29%), Positives = 512/1221 (41%), Gaps = 232/1221 (19%)
Query: 231 GRCFQETIGSQCGKALPGL-SKQEDCCGTVGTSWGFNKCQKCPKKPSYHGYNQMMECLPG 289
G CF + C L GL + CC TVG +WG C+ CP +P C G
Sbjct: 185 GPCFGQVGPEGCQHQLTGLVCTKALCCATVGRAWGL-PCELCPAQPH--------PCRRG 235
Query: 290 Y-KRVNNTFCQDINECQ-LQGVCPNGECLNTMGSYRCTCKIGFGPDPTFSSCVPDPPVIS 347
+ ++ CQD++ECQ + G+C G C+N +GS+ C C +G + ++C
Sbjct: 236 FIPNIHTGACQDVDECQAVPGLCQGGSCVNMVGSFHCRCPVGHRLSDSSAACE------D 289
Query: 348 EEKGPCYRLVSSGRQCMHPLSVHLTKQLCCCSVGKAW--GPHCEKCPLPGTAAFKEICPG 405
G C+ ++ GR C L+ H T++ CCC G+ W GP E CP G+ F+++C
Sbjct: 290 YRAGACFSVLFGGR-CAGDLAGHYTRRQCCCDRGRCWAAGPVPELCPPRGSNEFQQLC-- 346
Query: 406 GMGYTVSGVHRRRPIHHHVGKGPVFVKPKNTQPVAKSTHPPPLPAKEEPVEALTFSREHG 465
R + H G P + + PPL G
Sbjct: 347 --------AQRLPLLPGHPGLFPGLL------GFGSNGMGPPL----------------G 376
Query: 466 PGVAEPEVATAPPEKEIPSLDQEKTKLEPGQPQLSPGISTIHLHPQFPGIVIEKTSPPVP 525
P P + A + IPSL + + G L+ TI + F + + P P
Sbjct: 377 PARLNPHGSDA---RGIPSLGPGNSNI--GTATLN---QTIDICRHFTNLCLNGRCLPTP 428
Query: 526 VEVAPEASTSSASQVIAPTQVTEINECTVNPDICGAGHCINLPVRYTCICYEGYRFSEQQ 585
E + V + +++ECT +P C G C+N+P Y C CY G++ + +
Sbjct: 429 SSYRCECNVGYTQDVRG--ECIDVDECTSSP--CHHGDCVNIPGTYHCRCYPGFQATPTR 484
Query: 586 RKCVDIDECTQVQHLCSQGRCENTEGSFLCICPAGFMASEEGTNCIDVDECLRPDVCGEG 645
+ CVD+DEC LC GRC NTEGSF C+C AGF S +G NC+D +EC +C G
Sbjct: 485 QACVDVDECIVSGGLCHLGRCVNTEGSFQCVCNAGFELSPDGKNCVDHNECATSTMCVNG 544
Query: 646 HCVNTVGAFRCEYCDSGYRMTQRGR-CEDIDECLNPSTCPDEQCVNSPGSYQCVPCTEGF 704
C+N G+F C C G+ + G C DIDEC P C + C N+ GS++C C G
Sbjct: 545 VCLNEDGSFSC-LCKPGFLLAPGGHYCMDIDECQTPGICVNGHCTNTEGSFRC-QCLGGL 602
Query: 705 R-GWNGQ-CLDV------------DECLEP---------NVCANGDCSNLEGSYMCS--- 738
G +G+ C+D C P CAN D E +C
Sbjct: 603 AVGTDGRVCVDTHVRSTCYGAIEKGSCARPFPGTVTKSECCCANPDHGFGEPCQLCPAKD 662
Query: 739 -------CHKGYTRTPDHKHCRDIDECQ-QGNLCVNGQCKNTEGSFRCTCGQGYQLSAAK 790
C G T D RDI+EC +C NG C+N GS+RC C GY+ A+
Sbjct: 663 SAEFQALCSSGLGITTDG---RDINECALDPEVCANGVCENLRGSYRCVCNLGYEAGASG 719
Query: 791 DQCEDIDECQ-HRHLCAHGQCRNTEGSFQCVCDQGYRASGLGDHCEDINECLEDKSVCQR 849
C D+DEC + LC +G C+N+ GS+ C C G+ + C+D++ECL S C
Sbjct: 720 KDCTDVDECALNSLLCDNGWCQNSPGSYSCSCPPGFHFWQDTEICKDVDECL--SSPCVS 777
Query: 850 GDCINTAGSYDCTCPDGFQLDDNKT-CQDI-----------NECEHPGLCGP--QGECLN 895
G C N AGSY C C G +LD + T C D + CE L G + EC
Sbjct: 778 GVCRNLAGSYTCKCGPGSRLDPSGTFCLDSTKGTCWLKIQESRCE-VNLQGASLRSECCA 836
Query: 896 TEGS----------FHCVCQQGFSISADGRTCEDIDECVNNTVCDSHGFCDNTAGSFRCL 945
T G+ C +GF+ G TC+D++EC + +G C NTAGSFRC
Sbjct: 837 TLGAAWGSPCERCEIDPACARGFA-RMTGVTCDDVNECESFPGVCPNGRCVNTAGSFRCE 895
Query: 946 CYQGFQAPQDGQGCVDVNECELLSGVCGEAFCENVEGSFLCVCADENQEYSPMTGQCRSR 1005
C +G G+ CVDV +E FL
Sbjct: 896 CPEGLMLDASGRLCVDV----------------RLEPCFL-------------------- 919
Query: 1006 TSTDLDVDVDQPKEEKKECYYNLNDASLCDNVLAPNVTKQECCCTS-GAGWGDNCEIFPC 1064
+ ++ EC V P + + CC S GA WG CE C
Sbjct: 920 ------------RWDEDEC-----------GVTLPGKYRMDVCCCSIGAVWGVECE--AC 954
Query: 1065 PVLGTAEFTEMCPKGKGFVPAGESSSEAGGENYKDADECLLFGQEICKNGFCLNTRPGYE 1124
P + EF +CP+G GF S G YKD +EC +F +C +G C NT +
Sbjct: 955 PDPESLEFASLCPRGLGFASRDFLS---GRPFYKDVNECKVF-PGLCTHGTCRNTVGSFH 1010
Query: 1125 CYCKQGTYYDPVKLQCFDMDECQ-DPSSCIDGQCVNTEGSYNCFCTHPMVLDASEKRCIR 1183
C C G D + C D+DEC+ P C G CVNT GS+ C C
Sbjct: 1011 CACAGGFALDAQERNCTDIDECRISPDLCGQGTCVNTPGSFEC-------------ECFP 1057
Query: 1184 PAESNEQIEETDVYQDLCWEHLSDEYVCSRPLVGKQTTYTECCCLYGEAWGMQCALCPLK 1243
ES + + + D C D +C +C C G + C +
Sbjct: 1058 GYESGFMLMKNCMDVDEC---ARDPLLCRGGTCTNTDGSYKCQCPPGHELTAKGTAC--E 1112
Query: 1244 DSDDYAQLCNIPVTGRRQPYGRDALVDFSEQYTPEADPYFIQDRFLNSFEELQAEECGIL 1303
D D+ C++ + P+G+ V + Q + A DR + EC +
Sbjct: 1113 DIDE----CSL--SDGLCPHGQCVNVIGAFQCSCHAGFQSTPDR----QGCVDINECRVQ 1162
Query: 1304 NGCENGRCVRVQEGYTCDCFDGYHLDTAKMTCVDVNECDELNNRMSLCKNAKCINTDGSY 1363
NG + C+ + Y C C GY L C DV+EC+E N R +C C N G +
Sbjct: 1163 NGGCDVHCINTEGSYRCSCGQGYSLMPDGRACADVDECEE-NPR--VCDQGHCTNMPGGH 1219
Query: 1364 KCLCLPGYVPSDKPNYCTPLN 1384
+CLC G++ + C ++
Sbjct: 1220 RCLCYDGFMATPDMRTCVDVD 1240
Score = 448 bits (1152), Expect = e-125
Identities = 370/1326 (27%), Positives = 530/1326 (39%), Gaps = 276/1326 (20%)
Query: 243 GKALPGLSKQEDCCGTVGTSWGFNKC---QKCPKKPSYHGY------NQMMECLPGYKRV 293
G+ LP S C T +C +C P +HG C PG++
Sbjct: 422 GRCLPTPSSYRCECNVGYTQDVRGECIDVDECTSSPCHHGDCVNIPGTYHCRCYPGFQAT 481
Query: 294 -NNTFCQDINECQLQG-VCPNGECLNTMGSYRCTCKIGFGPDPTFSSCVPDPPVISEEKG 351
C D++EC + G +C G C+NT GS++C C GF P +CV +
Sbjct: 482 PTRQACVDVDECIVSGGLCHLGRCVNTEGSFQCVCNAGFELSPDGKNCV--------DHN 533
Query: 352 PCYRLVSSGRQCMHPLSVHLTKQLCC-CSVGKAWGP---HC---EKCPLPGTA------- 397
C ++ C++ + ++ C C G P +C ++C PG
Sbjct: 534 EC----ATSTMCVNGVCLNEDGSFSCLCKPGFLLAPGGHYCMDIDECQTPGICVNGHCTN 589
Query: 398 ---AFKEICPGGMGYTVSGVHRRRPIHHHVGKGPVFVKPKNTQPVAKSTHPPPLPAKEEP 454
+F+ C GG+ G R + HV + + K + P P
Sbjct: 590 TEGSFRCQCLGGLAVGTDG---RVCVDTHV-------RSTCYGAIEKGSCARPFPGTVTK 639
Query: 455 VEALTFSREHGPGVAEP-EVATAPPEKEIPSLDQEKTKL-----EPGQPQLSPGISTIHL 508
E + +HG G EP ++ A E +L + + + L P + +
Sbjct: 640 SECCCANPDHGFG--EPCQLCPAKDSAEFQALCSSGLGITTDGRDINECALDPEVCANGV 697
Query: 509 HPQFPGIVIEKTSPPVPVEVAPEASTSSASQVIAPTQVTEINECTVNPDICGAGHCINLP 568
G S + EA S T+++EC +N +C G C N P
Sbjct: 698 CENLRG------SYRCVCNLGYEAGASGKD-------CTDVDECALNSLLCDNGWCQNSP 744
Query: 569 VRYTCICYEGYRFSEQQRKCVDIDECTQVQHLCSQGRCENTEGSFLCICPAGFMASEEGT 628
Y+C C G+ F + C D+DEC + C G C N GS+ C C G GT
Sbjct: 745 GSYSCSCPPGFHFWQDTEICKDVDEC--LSSPCVSGVCRNLAGSYTCKCGPGSRLDPSGT 802
Query: 629 NCIDVDECL--------RPDVCGEG-----HCVNTVGAF------RCEY---CDSGYRMT 666
C+D + R +V +G C T+GA RCE C G+
Sbjct: 803 FCLDSTKGTCWLKIQESRCEVNLQGASLRSECCATLGAAWGSPCERCEIDPACARGFARM 862
Query: 667 QRGRCEDIDECLN-PSTCPDEQCVNSPGSYQCVPCTEGFR--GWNGQCLDV--------- 714
C+D++EC + P CP+ +CVN+ GS++C C EG C+DV
Sbjct: 863 TGVTCDDVNECESFPGVCPNGRCVNTAGSFRC-ECPEGLMLDASGRLCVDVRLEPCFLRW 921
Query: 715 --DEC---------LEPNVCANG-----------DCSNLEGSYMCSCHKGYTRTP---DH 749
DEC ++ C+ G D +LE + +C G+
Sbjct: 922 DEDECGVTLPGKYRMDVCCCSIGAVWGVECEACPDPESLEFASLCPRGLGFASRDFLSGR 981
Query: 750 KHCRDIDECQQ-GNLCVNGQCKNTEGSFRCTCGQGYQLSAAKDQCEDIDECQ-HRHLCAH 807
+D++EC+ LC +G C+NT GSF C C G+ L A + C DIDEC+ LC
Sbjct: 982 PFYKDVNECKVFPGLCTHGTCRNTVGSFHCACAGGFALDAQERNCTDIDECRISPDLCGQ 1041
Query: 808 GQCRNTEGSFQCVCDQGYRASG-LGDHCEDINECLEDKSVCQRGDCINTAGSYDCTCPDG 866
G C NT GSF+C C GY + L +C D++EC D +C+ G C NT GSY C CP G
Sbjct: 1042 GTCVNTPGSFECECFPGYESGFMLMKNCMDVDECARDPLLCRGGTCTNTDGSYKCQCPPG 1101
Query: 867 FQLDDNKT-CQDINECE-HPGLCGPQGECLNTEGSFHCVCQQGFSISADGRTCEDIDEC- 923
+L T C+DI+EC GLC P G+C+N G+F C C GF + D + C DI+EC
Sbjct: 1102 HELTAKGTACEDIDECSLSDGLC-PHGQCVNVIGAFQCSCHAGFQSTPDRQGCVDINECR 1160
Query: 924 VNNTVCDSHGFCDNTAGSFRCLCYQGFQAPQDGQGCVDVNECELLSGVCGEAFCENVEGS 983
V N CD H C NT GS+RC C QG+ DG+ C DV+ECE VC + C N+ G
Sbjct: 1161 VQNGGCDVH--CINTEGSYRCSCGQGYSLMPDGRACADVDECEENPRVCDQGHCTNMPGG 1218
Query: 984 FLCVCADENQEYSPMTGQCRSRTSTDLDVDVDQPKEEKKECYY----NLNDASLCDNVLA 1039
C+C D +P C VDVD+ C + N + +C L
Sbjct: 1219 HRCLCYDGFMA-TPDMRTC---------VDVDECDLNPHICLHGDCENTKGSFVCHCQLG 1268
Query: 1040 PNVTKQECCCT---SGAGWGDNCEIFPCPVLGTAEFTEMCPK---GKGF----------- 1082
V K C+ G NC+ + F+ C G GF
Sbjct: 1269 YMVRKGATGCSDVDECEVGGHNCDSHASCLNIPGSFSCRCLPGWVGDGFECHDLDECVSQ 1328
Query: 1083 ----VPAGESSSEAG-----------GENY--KDADECLLFGQEICKNGFCLNTRPGYEC 1125
P G+ + G G+ + +D DEC ++C NG CLN GY C
Sbjct: 1329 EHRCSPRGDCLNVPGSYRCTCRQGFAGDGFFCEDRDEC-AENVDLCDNGQCLNAPGGYRC 1387
Query: 1126 YCKQGTYYDPVK-------------------------------------------LQCFD 1142
C+ G +DP + C D
Sbjct: 1388 ECEMG--FDPTEDHRACQDVDECAQGNLCAFGSCENLPGMFRCICNGGYELDRGGGNCTD 1445
Query: 1143 MDECQDPSSCIDGQCVNTEGSYNCFCTHPMVLDASEKRCIRPAESNEQIEETDVYQDLCW 1202
++EC DP +CI+G C+NT GSY C C L+ S C+ N +E D
Sbjct: 1446 INECADPVNCINGVCINTPGSYLCSCPQDFELNPSGVGCVDTRAGNCFLETHD------- 1498
Query: 1203 EHLSDEYVCSRPLVGKQTTYTECCCLYGEAWGMQCALCPLKDSDDYAQLCNIPVTGRRQP 1262
D + +G T CCC G AWG C LCP+ ++ +Y LC P
Sbjct: 1499 --RGDSGISCSAEIGVGVTRASCCCSLGRAWGNPCELCPMANTTEYRTLC---------P 1547
Query: 1263 YGRDALVDFSEQYTPEADPYFIQDRFLNSFEELQAEECGILNG-CENGRCVRVQEGYTCD 1321
G E + P ++D +EC L G C+ G CV + C+
Sbjct: 1548 GG--------EGFQPNRITVILED----------IDECQELPGLCQGGDCVNTFGSFQCE 1589
Query: 1322 CFDGYHLDTAKMTCVDVNECDELNNRMSLCKNAKCINTDGSYKCLCLPGYVPSDKPNYCT 1381
C GYHL C D++EC + +C C NT G+Y C+C Y+ + N C
Sbjct: 1590 CPPGYHLSEHTRICEDIDEC---STHSGICGPGTCYNTLGNYTCVCPAEYLQVNGGNNCM 1646
Query: 1382 PLNTAL 1387
+ ++
Sbjct: 1647 DMRKSV 1652
Score = 408 bits (1048), Expect = e-113
Identities = 276/844 (32%), Positives = 382/844 (45%), Gaps = 104/844 (12%)
Query: 525 PVEVAPEASTSS------ASQVIAPTQVT----EINECTVNPDICGAGHCINLPVRYTCI 574
P E+ P A+T+ + P ++T +I+EC P +C G C+N + C
Sbjct: 1530 PCELCPMANTTEYRTLCPGGEGFQPNRITVILEDIDECQELPGLCQGGDCVNTFGSFQCE 1589
Query: 575 CYEGYRFSEQQRKCVDIDECTQVQHLCSQGRCENTEGSFLCICPAGFMASEEGTNCIDVD 634
C GY SE R C DIDEC+ +C G C NT G++ C+CPA ++ G NC+D
Sbjct: 1590 CPPGYHLSEHTRICEDIDECSTHSGICGPGTCYNTLGNYTCVCPAEYLQVNGGNNCMD-- 1647
Query: 635 ECLRPDVCGE---GHCVNTVGAFRC--EYCDSGYRMTQRGRCEDIDECLNPSTCPDEQ-- 687
+R VC G C N + AF + C Y + Q + C P + PD Q
Sbjct: 1648 --MRKSVCFRHYNGTCQNEL-AFNVTRKMCCCSYNIGQAWN-RPCEACPTPIS-PDYQIL 1702
Query: 688 CVN-SPGSYQCVPCTEGFRGWNGQCLDVDECLE-PNVCANGDCSNLEGSYMCSCHKGYTR 745
C N +PG + G+ LD+DEC E P +CANG C N GS+ C C G+
Sbjct: 1703 CGNQAPGFLTDIH--------TGKPLDIDECGEIPAICANGICINQIGSFRCECPAGFNY 1754
Query: 746 TPDHKHCRDIDEC--QQGNLCVNGQCKNTEGSFRCTCGQGYQLSAAKDQCEDIDECQH-R 802
C D+DEC ++ N C N GS+RC C +GY+LS C +EC+
Sbjct: 1755 NSILLACEDVDECGSRESPCQQNADCINIPGSYRCKCTRGYKLSPG-GACVGRNECREIP 1813
Query: 803 HLCAHGQCRNTEGSFQCVCDQGYRASGLGDHCEDINECLEDKSVCQRGDCINTAGSYDCT 862
++C+HG C +TEGS+ C+C +G++AS C DI+EC D+ C G C N GSY+C
Sbjct: 1814 NVCSHGDCMDTEGSYMCLCHRGFQASADQTLCMDIDEC--DRQPCGNGTCKNIIGSYNCL 1871
Query: 863 CPDGFQLDDNKTCQDINECEH-PGLCGPQGECLNTEGSFHCVCQQGFSISADGRTCEDID 921
C GF + N C D +EC G G CLNT GSFHC+CQ GF ++ADG+ C D +
Sbjct: 1872 CFPGFVVTHNGDCVDFDECTTLVGQVCRFGHCLNTAGSFHCLCQDGFELTADGKNCVDTN 1931
Query: 922 ECVNNTVCDSHGFCDNTAGSFRCLCYQGFQAPQDGQGCVDVNECELLSGVCGEAFCENVE 981
EC++ G C N GSFRC+C GFQ D C+D++EC +C C N
Sbjct: 1932 ECLSLAGTCLPGTCQNLEGSFRCICPPGFQVQSD--HCIDIDECSEEPNLCLFGTCTNSP 1989
Query: 982 GSFLCVCADENQEYSPMTGQCRSRTSTDLDVDVDQPKEEKKECYYNLNDASLCDNVLAPN 1041
GSF C+C L + + + ++ + +A C A N
Sbjct: 1990 GSFQCLCP----------------PGFVLSDNGHRCFDTRQSFCFTRFEAGKCSVPKAFN 2033
Query: 1042 VTKQECCCTS--GAGWGDNCEIFPCPVLGTAEFTEMCPKGKGFVPAGESSSEAGGENYKD 1099
TK CCC+ G GWGD CE+ CP G+A F E+CP G G VP + S E D
Sbjct: 2034 TTKTRCCCSKRPGEGWGDPCEL--CPQEGSAAFQELCPFGHGAVPGPDDSRE-------D 2084
Query: 1100 ADECLLFGQEICKNGFCLNTRPGYECYCKQGTYYDPVKLQCFDMDECQDPSSCIDGQCVN 1159
+EC +C NG C+NT + C C G D + C D DEC C G C N
Sbjct: 2085 VNEC-AENPGVCTNGVCVNTDGSFRCECPFGYSLDFTGINCVDTDECSVGHPCGQGTCTN 2143
Query: 1160 TEGSYNCFCTHPMVLDASEKRCIRPAESNEQIEETDVYQDLCWEHLSDEYVCSRPLVGKQ 1219
G + C C D E + E I+E + LC + C +
Sbjct: 2144 VIGGFECACA-----DGFEPGLMMTC---EDIDECSLNPLLC------AFRCH----NTE 2185
Query: 1220 TTYTECCCLYGEAWGMQCALCPLKDSDDYA---QLCNIPVTGRRQPYGRDALVDFSEQYT 1276
+Y C C G A+C +D D+ A Q C+ R ++ + F+
Sbjct: 2186 GSYL-CTCPAGYTLREDGAMC--RDVDECADGQQDCH-----ARGMECKNLIGTFACVCP 2237
Query: 1277 PEADPYFIQDRFLNSFEELQAEECGILNGCENGRCVRVQEGYTCDCFDGYHLDTAKMTCV 1336
P P E A+ + C NGRCV + CDC +G+ C
Sbjct: 2238 PGMRPLPGSGEGCTDDNECHAQP----DLCVNGRCVNTAGSFRCDCDEGFQPSPTLTECH 2293
Query: 1337 DVNE 1340
D+ +
Sbjct: 2294 DIRQ 2297
Score = 381 bits (979), Expect = e-105
Identities = 269/884 (30%), Positives = 394/884 (44%), Gaps = 169/884 (19%)
Query: 550 NECTVNPDICGAGHCINLPVRYTCICYEGYRFSEQQRKCVDIDECTQVQHLCSQGRCENT 609
NEC P++C G C++ Y C+C+ G++ S Q C+DIDEC + C G C+N
Sbjct: 1807 NECREIPNVCSHGDCMDTEGSYMCLCHRGFQASADQTLCMDIDECDRQP--CGNGTCKNI 1864
Query: 610 EGSFLCICPAGFMASEEGTNCIDVDEC--LRPDVCGEGHCVNTVGAFRCEYCDSGYRMTQ 667
GS+ C+C GF+ + G +C+D DEC L VC GHC+NT G+F C C G+ +T
Sbjct: 1865 IGSYNCLCFPGFVVTHNG-DCVDFDECTTLVGQVCRFGHCLNTAGSFHC-LCQDGFELTA 1922
Query: 668 RGR-CEDIDECLN-PSTCPDEQCVNSPGSYQCVPCTEGFRGWNGQCLDVDECLE-PNVCA 724
G+ C D +ECL+ TC C N GS++C+ C GF+ + C+D+DEC E PN+C
Sbjct: 1923 DGKNCVDTNECLSLAGTCLPGTCQNLEGSFRCI-CPPGFQVQSDHCIDIDECSEEPNLCL 1981
Query: 725 NGDCSNLEGSYMCSCHKGYTRTPDHKHCRDIDECQQGNLCVNGQCK-----NTEGSFRCT 779
G C+N GS+ C C G+ + + C D + G+C NT + RC
Sbjct: 1982 FGTCTNSPGSFQCLCPPGFVLSDNGHRCFDTRQSFCFTRFEAGKCSVPKAFNTTKT-RCC 2040
Query: 780 C----GQGY---------QLSAA---------------KDQCEDIDEC-QHRHLCAHGQC 810
C G+G+ + SAA D ED++EC ++ +C +G C
Sbjct: 2041 CSKRPGEGWGDPCELCPQEGSAAFQELCPFGHGAVPGPDDSREDVNECAENPGVCTNGVC 2100
Query: 811 RNTEGSFQCVCDQGYRASGLGDHCEDINECLEDKSVCQRGDCINTAGSYDCTCPDGFQLD 870
NT+GSF+C C GY G +C D +EC C +G C N G ++C C DGF+
Sbjct: 2101 VNTDGSFRCECPFGYSLDFTGINCVDTDECSVGHP-CGQGTCTNVIGGFECACADGFEPG 2159
Query: 871 DNKTCQDINECE-HPGLCGPQGECLNTEGSFHCVCQQGFSISADGRTCEDIDECVNNTV- 928
TC+DI+EC +P LC + C NTEGS+ C C G+++ DG C D+DEC +
Sbjct: 2160 LMMTCEDIDECSLNPLLCAFR--CHNTEGSYLCTCPAGYTLREDGAMCRDVDECADGQQD 2217
Query: 929 CDSHGF-CDNTAGSFRCLCYQGFQA-PQDGQGCVDVNECELLSGVCGEAFCENVEGSFLC 986
C + G C N G+F C+C G + P G+GC D NEC +C C N GSF C
Sbjct: 2218 CHARGMECKNLIGTFACVCPPGMRPLPGSGEGCTDDNECHAQPDLCVNGRCVNTAGSFRC 2277
Query: 987 VCADENQEYSPMTGQCRSRTSTDLDVDVDQPKEEKKECYYNLNDASLCDNVLAPN--VTK 1044
C DE + SP +C +V Q ++C ++ + + VT+
Sbjct: 2278 DC-DEGFQPSPTLTECHDIRQGPCFAEVLQ---------------TMCRSLSSSSEAVTR 2321
Query: 1045 QECCCTSGAGWGDNCEIFPCPVLGTAEFTEMCPKGKGFVPAGESSSEAGGENYKDADECL 1104
ECCC G GWG CE+ CP+ GT+ +
Sbjct: 2322 AECCCGGGRGWGPRCEL--CPLPGTSAY-------------------------------- 2347
Query: 1105 LFGQEICKNGFCLNTRPGYECYCKQGTYYDPVKLQCFDMDECQDPSS-CIDGQCVNTEGS 1163
+++C +G Y +G D+DEC+ + C G+C+N+ GS
Sbjct: 2348 ---RKLCPHG---------SGYTAEGR----------DVDECRMLAHLCAHGECINSLGS 2385
Query: 1164 YNCFCTHPMVLDASEKRCIRPAESNEQIEETDVYQDLCWEHLSDEYVCSRPLVGKQTTYT 1223
+ C C DA+ C+ E + Q+ + + LC ++ ++CS P
Sbjct: 2386 FRCHCQAGYTPDATATTCLDMDECS-QVPKPCTF--LC-KNTKGSFLCSCPRG------- 2434
Query: 1224 ECCCLYGEAWGMQCALCPLKDSDDYAQLCNIPVTGRRQPYGRDALVDFSEQYTPEADPYF 1283
E G C KD D+ RQ + V+ +T P F
Sbjct: 2435 ----YLLEEDGRTC-----KDLDECTS---------RQHNCQFLCVNTVGAFTCRCPPGF 2476
Query: 1284 IQDR---FLNSFEELQAEECGILNGCENGRCVRVQEGYTCDCFDGYHLDTAKMTCVDVNE 1340
Q F N Q CG +G C + C+C G+ L ++ C DVNE
Sbjct: 2477 TQHHQACFDNDECSAQPGPCGA-----HGHCHNTPGSFRCECHQGFTLVSSGHGCEDVNE 2531
Query: 1341 CDELNNRMSLCKNAKCINTDGSYKCLCLPGYVPSDKPNYCTPLN 1384
CD + C++ C N G Y+C C G+ + C N
Sbjct: 2532 CDGPHR----CQHG-CQNQLGGYRCSCPQGFTQHSQWAQCVDEN 2570
Score = 379 bits (974), Expect = e-105
Identities = 318/1012 (31%), Positives = 421/1012 (41%), Gaps = 208/1012 (20%)
Query: 547 TEINECTVNPDICGAGHCINLPVRYTCICYEGYRFSEQQRKCVDI--DEC---------- 594
T+INEC +P C G CIN P Y C C + + + CVD C
Sbjct: 1444 TDINECA-DPVNCINGVCINTPGSYLCSCPQDFELNPSGVGCVDTRAGNCFLETHDRGDS 1502
Query: 595 ------------TQVQHLCSQGR-----CE------NTEGSFLCICPAGFMASEEGTNCI 631
T+ CS GR CE TE LC GF +
Sbjct: 1503 GISCSAEIGVGVTRASCCCSLGRAWGNPCELCPMANTTEYRTLCPGGEGFQPNRITVILE 1562
Query: 632 DVDECLR-PDVCGEGHCVNTVGAFRCEYCDSGYRMTQRGR-CEDIDECLNPS-TCPDEQC 688
D+DEC P +C G CVNT G+F+CE C GY +++ R CEDIDEC S C C
Sbjct: 1563 DIDECQELPGLCQGGDCVNTFGSFQCE-CPPGYHLSEHTRICEDIDECSTHSGICGPGTC 1621
Query: 689 VNSPGSYQCVPCTEGFRGWNG--QCLDVDECLEPNVCA---NGDCSNLEGSY-----MCS 738
N+ G+Y CV C + NG C+D + +VC NG C N E ++ MC
Sbjct: 1622 YNTLGNYTCV-CPAEYLQVNGGNNCMD----MRKSVCFRHYNGTCQN-ELAFNVTRKMCC 1675
Query: 739 CH----KGYTR---------TPDHKHC-----------------RDIDECQQ-GNLCVNG 767
C + + R +PD++ DIDEC + +C NG
Sbjct: 1676 CSYNIGQAWNRPCEACPTPISPDYQILCGNQAPGFLTDIHTGKPLDIDECGEIPAICANG 1735
Query: 768 QCKNTEGSFRCTCGQGYQLSAAKDQCEDIDECQHRHLCA--HGQCRNTEGSFQCVCDQGY 825
C N GSFRC C G+ ++ CED+DEC R + C N GS++C C +GY
Sbjct: 1736 ICINQIGSFRCECPAGFNYNSILLACEDVDECGSRESPCQQNADCINIPGSYRCKCTRGY 1795
Query: 826 RASGLGDHCEDINECLEDKSVCQRGDCINTAGSYDCTCPDGFQLDDNKT-CQDINECEHP 884
+ S G C NEC E +VC GDC++T GSY C C GFQ ++T C DI+EC+
Sbjct: 1796 KLSP-GGACVGRNECREIPNVCSHGDCMDTEGSYMCLCHRGFQASADQTLCMDIDECDRQ 1854
Query: 885 GLCGPQGECLNTEGSFHCVCQQGFSISADGRTCEDIDECVN--NTVCDSHGFCDNTAGSF 942
CG G C N GS++C+C GF ++ +G C D DEC VC G C NTAGSF
Sbjct: 1855 P-CG-NGTCKNIIGSYNCLCFPGFVVTHNG-DCVDFDECTTLVGQVC-RFGHCLNTAGSF 1910
Query: 943 RCLCYQGFQAPQDGQGCVDVNECELLSGVCGEAFCENVEGSFLCVCA------------- 989
CLC GF+ DG+ CVD NEC L+G C C+N+EGSF C+C
Sbjct: 1911 HCLCQDGFELTADGKNCVDTNECLSLAGTCLPGTCQNLEGSFRCICPPGFQVQSDHCIDI 1970
Query: 990 DENQEY-----------SPMTGQCRSRTSTDLDVDVDQPKEEKKECYYNLNDASLCDNVL 1038
DE E SP + QC L + + + ++ + +A C
Sbjct: 1971 DECSEEPNLCLFGTCTNSPGSFQCLCPPGFVLSDNGHRCFDTRQSFCFTRFEAGKCSVPK 2030
Query: 1039 APNVTKQECCCTS--GAGWGDNCEIFPCPVLGTAEFTEMCPKGKGFVPAGESSSEAGGEN 1096
A N TK CCC+ G GWGD CE+ CP G+A F E+CP G G VP + S E
Sbjct: 2031 AFNTTKTRCCCSKRPGEGWGDPCEL--CPQEGSAAFQELCPFGHGAVPGPDDSRE----- 2083
Query: 1097 YKDADECLLFGQEICKNGFCLNTRPGYECYCKQGTYYDPVKLQCFDMDECQDPSSCIDGQ 1156
D +EC +C NG C+NT + C C G D + C D DEC C G
Sbjct: 2084 --DVNECAE-NPGVCTNGVCVNTDGSFRCECPFGYSLDFTGINCVDTDECSVGHPCGQGT 2140
Query: 1157 CVNTEGSYNCFCTHPMVLDASEKRCIRPAESNEQIEETDVYQDLC---WEHLSDEYVCSR 1213
C N G + C C D E + E I+E + LC + Y+C+
Sbjct: 2141 CTNVIGGFECACA-----DGFEPGLMMTCED---IDECSLNPLLCAFRCHNTEGSYLCTC 2192
Query: 1214 PLVGKQTTYTECC-----CLYGE----AWGMQC--------ALCP-------------LK 1243
P C C G+ A GM+C +CP
Sbjct: 2193 PAGYTLREDGAMCRDVDECADGQQDCHARGMECKNLIGTFACVCPPGMRPLPGSGEGCTD 2252
Query: 1244 DSDDYAQ--LCNIPVTGRRQPYGRDALVDFSEQYTPEADPYFIQD-RFLNSFEELQAEEC 1300
D++ +AQ LC V GR D E + P D R F E+ C
Sbjct: 2253 DNECHAQPDLC---VNGRCVNTAGSFRCDCDEGFQPSPTLTECHDIRQGPCFAEVLQTMC 2309
Query: 1301 GILNG-----------CENGRCVRVQEGYTCDCFDGYHLDTAKMTCV----------DVN 1339
L+ C GR G C+ + C DV+
Sbjct: 2310 RSLSSSSEAVTRAECCCGGGR----GWGPRCELCPLPGTSAYRKLCPHGSGYTAEGRDVD 2365
Query: 1340 ECDELNNRMSLCKNAKCINTDGSYKCLCLPGYVPSDKPNYCTPLNTALNLEK 1391
EC L + LC + +CIN+ GS++C C GY P C ++ + K
Sbjct: 2366 ECRMLAH---LCAHGECINSLGSFRCHCQAGYTPDATATTCLDMDECSQVPK 2414
Score = 377 bits (969), Expect = e-104
Identities = 269/844 (31%), Positives = 364/844 (43%), Gaps = 159/844 (18%)
Query: 587 KCVDIDECTQVQHLCSQGRCENTEGSFLCICPAGFMASEEGTNCIDVDEC-LRPDVCGEG 645
K +DIDEC ++ +C+ G C N GSF C CPAGF + C DVDEC R C +
Sbjct: 1718 KPLDIDECGEIPAICANGICINQIGSFRCECPAGFNYNSILLACEDVDECGSRESPCQQN 1777
Query: 646 -HCVNTVGAFRCEYCDSGYRMTQRGRCEDIDECLN-PSTCPDEQCVNSPGSYQCVPCTEG 703
C+N G++RC+ C GY+++ G C +EC P+ C C+++ GSY C+ C G
Sbjct: 1778 ADCINIPGSYRCK-CTRGYKLSPGGACVGRNECREIPNVCSHGDCMDTEGSYMCL-CHRG 1835
Query: 704 FRGWNGQ--CLDVDECLEPNVCANGDCSNLEGSYMCSCHKGYTRTPDHKHCRDIDECQQ- 760
F+ Q C+D+DEC + C NG C N+ GSY C C G+ T + C D DEC
Sbjct: 1836 FQASADQTLCMDIDEC-DRQPCGNGTCKNIIGSYNCLCFPGFVVT-HNGDCVDFDECTTL 1893
Query: 761 -GNLCVNGQCKNTEGSFRCTCGQGYQLSAAKDQCEDIDECQH-RHLCAHGQCRNTEGSFQ 818
G +C G C NT GSF C C G++L+A C D +EC C G C+N EGSF+
Sbjct: 1894 VGQVCRFGHCLNTAGSFHCLCQDGFELTADGKNCVDTNECLSLAGTCLPGTCQNLEGSFR 1953
Query: 819 CVCDQGYRASGLGDHCEDINECLEDKSVCQRGDCINTAGSYDCTCPDGFQLDDN-KTCQD 877
C+C G++ DHC DI+EC E+ ++C G C N+ GS+ C CP GF L DN C D
Sbjct: 1954 CICPPGFQVQS--DHCIDIDECSEEPNLCLFGTCTNSPGSFQCLCPPGFVLSDNGHRCFD 2011
Query: 878 INECE-----HPGLC-----------------------GPQGECLNTEGS--FHCVCQQG 907
+ G C G E EGS F +C G
Sbjct: 2012 TRQSFCFTRFEAGKCSVPKAFNTTKTRCCCSKRPGEGWGDPCELCPQEGSAAFQELCPFG 2071
Query: 908 F-SISADGRTCEDIDECVNNTVCDSHGFCDNTAGSFRCLCYQGFQAPQDGQGCVDVNECE 966
++ + ED++EC N ++G C NT GSFRC C G+ G CVD +EC
Sbjct: 2072 HGAVPGPDDSREDVNECAENPGVCTNGVCVNTDGSFRCECPFGYSLDFTGINCVDTDECS 2131
Query: 967 LLSGVCGEAFCENVEGSFLCVCADENQEYSPMTGQCRSRTSTDLDVDVDQPKEEKKECYY 1026
+ CG+ C NV G F C CAD + MT + D+D EC
Sbjct: 2132 V-GHPCGQGTCTNVIGGFECACADGFEPGLMMTCE-----------DID-------ECSL 2172
Query: 1027 N-LNDASLCDNVLAPNVTKQECCCTSGAGWGDNCEIFPCPVLGTAEFTEMCPKGKGFVPA 1085
N L A C N T+ CT AG+ E MC
Sbjct: 2173 NPLLCAFRCHN------TEGSYLCTCPAGYT------------LREDGAMC--------- 2205
Query: 1086 GESSSEAGGENYKDADECLLFGQEICKNGF-CLNTRPGYECYCKQGTYYDPVKLQ-CFDM 1143
+D DEC Q+ G C N + C C G P + C D
Sbjct: 2206 ------------RDVDECADGQQDCHARGMECKNLIGTFACVCPPGMRPLPGSGEGCTDD 2253
Query: 1144 DECQ-DPSSCIDGQCVNTEGSYNCFCTHPMVLDASEKRCIRPAESNEQIEETDVYQDLCW 1202
+EC P C++G+CVNT GS+ C C + C D+ Q C+
Sbjct: 2254 NECHAQPDLCVNGRCVNTAGSFRCDCDEGFQPSPTLTEC------------HDIRQGPCF 2301
Query: 1203 EHLSDEYVCSRPLVGKQTTYTECCCLYGEAWGMQCALCPLKDSDDYAQLCNIPVTGRRQP 1262
+ S + T ECCC G WG +C LCPL + Y +LC P
Sbjct: 2302 AEVLQTMCRSLSSSSEAVTRAECCCGGGRGWGPRCELCPLPGTSAYRKLC---------P 2352
Query: 1263 YGRDALVDFSEQYTPEADPYFIQDRFLNSFEELQAEECGIL-NGCENGRCVRVQEGYTCD 1321
+G YT E +EC +L + C +G C+ + C
Sbjct: 2353 HG--------SGYTAEG---------------RDVDECRMLAHLCAHGECINSLGSFRCH 2389
Query: 1322 CFDGYHLDTAKMTCVDVNECDELNNRMS-LCKNAKCINTDGSYKCLCLPGYVPSDKPNYC 1380
C GY D TC+D++EC ++ + LCKN K GS+ C C GY+ + C
Sbjct: 2390 CQAGYTPDATATTCLDMDECSQVPKPCTFLCKNTK-----GSFLCSCPRGYLLEEDGRTC 2444
Query: 1381 TPLN 1384
L+
Sbjct: 2445 KDLD 2448
Score = 376 bits (965), Expect = e-104
Identities = 277/872 (31%), Positives = 376/872 (43%), Gaps = 159/872 (18%)
Query: 544 TQVTEINECTVNPDICGAGHCINLPVRYTCICYEGYRFSEQQRKCVDIDECTQ-VQHLCS 602
T +I+EC P CG G C N+ Y C+C+ G+ + CVD DECT V +C
Sbjct: 1843 TLCMDIDECDRQP--CGNGTCKNIIGSYNCLCFPGFVVTHNG-DCVDFDECTTLVGQVCR 1899
Query: 603 QGRCENTEGSFLCICPAGFMASEEGTNCIDVDECLR-PDVCGEGHCVNTVGAFRCEYCDS 661
G C NT GSF C+C GF + +G NC+D +ECL C G C N G+FRC C
Sbjct: 1900 FGHCLNTAGSFHCLCQDGFELTADGKNCVDTNECLSLAGTCLPGTCQNLEGSFRC-ICPP 1958
Query: 662 GYRMTQRGRCEDIDECLN-PSTCPDEQCVNSPGSYQCVPCTEGF-RGWNG-QCLDVDE-- 716
G+++ Q C DIDEC P+ C C NSPGS+QC+ C GF NG +C D +
Sbjct: 1959 GFQV-QSDHCIDIDECSEEPNLCLFGTCTNSPGSFQCL-CPPGFVLSDNGHRCFDTRQSF 2016
Query: 717 ---------CLEPNV---------CAN------GDCSNL---EGSY----MCSCHKGYTR 745
C P C+ GD L EGS +C G
Sbjct: 2017 CFTRFEAGKCSVPKAFNTTKTRCCCSKRPGEGWGDPCELCPQEGSAAFQELCPFGHGAVP 2076
Query: 746 TPDHKHCRDIDECQQG-NLCVNGQCKNTEGSFRCTCGQGYQLSAAKDQCEDIDECQHRHL 804
PD D++EC + +C NG C NT+GSFRC C GY L C D DEC H
Sbjct: 2077 GPDDSR-EDVNECAENPGVCTNGVCVNTDGSFRCECPFGYSLDFTGINCVDTDECSVGHP 2135
Query: 805 CAHGQCRNTEGSFQCVCDQGYRASGLGDHCEDINECLEDKSVCQRGDCINTAGSYDCTCP 864
C G C N G F+C C G+ GL CEDI+EC + +C C NT GSY CTCP
Sbjct: 2136 CGQGTCTNVIGGFECACADGFE-PGLMMTCEDIDECSLNPLLC-AFRCHNTEGSYLCTCP 2193
Query: 865 DGFQL-DDNKTCQDINEC-EHPGLCGPQG-ECLNTEGSFHCVCQQGF-SISADGRTCEDI 920
G+ L +D C+D++EC + C +G EC N G+F CVC G + G C D
Sbjct: 2194 AGYTLREDGAMCRDVDECADGQQDCHARGMECKNLIGTFACVCPPGMRPLPGSGEGCTDD 2253
Query: 921 DECVNNTVCDSHGFCDNTAGSFRCLCYQGFQAPQDGQGCVDVNECELLSGVCGEAFCENV 980
+EC +G C NTAGSFRC C +GFQ C D+ + G F E +
Sbjct: 2254 NECHAQPDLCVNGRCVNTAGSFRCDCDEGFQPSPTLTECHDIRQ--------GPCFAEVL 2305
Query: 981 EGSFLCVCADENQEYSPMTGQCRSRTSTDLDVDVDQPKEEKKECYYNLNDASLCDNVLAP 1040
+ CRS +S+ +
Sbjct: 2306 Q------------------TMCRSLSSS------------------------------SE 2317
Query: 1041 NVTKQECCCTSGAGWGDNCEIFPCPVLGTAEFTEMCPKGKGFVPAGESSSEAGGENYKDA 1100
VT+ ECCC G GWG CE+ CP+ GT+ + ++CP G G+ G +D
Sbjct: 2318 AVTRAECCCGGGRGWGPRCEL--CPLPGTSAYRKLCPHGSGYTAEG-----------RDV 2364
Query: 1101 DECLLFGQEICKNGFCLNTRPGYECYCKQGTYYDPVKLQCFDMDECQDPSSCIDGQCVNT 1160
DEC + +C +G C+N+ + C+C+ G D C DMDEC C NT
Sbjct: 2365 DECRMLA-HLCAHGECINSLGSFRCHCQAGYTPDATATTCLDMDECSQVPKPCTFLCKNT 2423
Query: 1161 EGSYNCFCTHPMVLDASEKRCIRPAESNEQIEETDVYQDLCWEHLSDEYVCSRPLVGKQT 1220
+GS+ C C +L+ + C + ++E Q C +++C VG T
Sbjct: 2424 KGSFLCSCPRGYLLEEDGRTC-------KDLDECTSRQHNC------QFLCVN-TVGAFT 2469
Query: 1221 TYTECCCLYGEAWGMQCALCPLKDSDD-YAQLCNIPVTGRRQPYGRDALVDFSEQYTPEA 1279
C C G Q D+D+ AQ G + + +T +
Sbjct: 2470 ----CRCPPGFTQHHQACF----DNDECSAQPGPCGAHGHCHNTPGSFRCECHQGFTLVS 2521
Query: 1280 DPYFIQDRFLNSFEELQAEECGILNGCENGRCVRVQEGYTCDCFDGYHLDTAKMTCVDVN 1339
+ +D EC + C++G C GY C C G+ + CVD N
Sbjct: 2522 SGHGCED----------VNECDGPHRCQHG-CQNQLGGYRCSCPQGFTQHSQWAQCVDEN 2570
Query: 1340 ECDELNNRMSLCKNAKCINTDGSYKCLCLPGY 1371
EC C +A C NT G ++C+C G+
Sbjct: 2571 EC---ALSPPTCGSASCRNTLGGFRCVCPSGF 2599
Score = 365 bits (937), Expect = e-100
Identities = 279/946 (29%), Positives = 385/946 (40%), Gaps = 195/946 (20%)
Query: 550 NECTVNPDICGAGHCINLPVRYTCICYEGYRFSEQQRKCVDIDECTQVQHLCSQGRCENT 609
+EC N D+C G C+N P Y C C G+ +E R C D+DEC Q +LC+ G CEN
Sbjct: 1364 DECAENVDLCDNGQCLNAPGGYRCECEMGFDPTEDHRACQDVDECAQ-GNLCAFGSCENL 1422
Query: 610 EGSFLCICPAGFMASEEGTNCIDVDECLRPDVCGEGHCVNTVGAFRCEYCDSGYRM---- 665
G F CIC G+ G NC D++EC P C G C+NT G++ C C + +
Sbjct: 1423 PGMFRCICNGGYELDRGGGNCTDINECADPVNCINGVCINTPGSYLCS-CPQDFELNPSG 1481
Query: 666 -----TQRGRC--EDIDECLNPSTCPDEQCVNSPGSYQCVPCTEGFRGWNGQCL------ 712
T+ G C E D + +C E V + C C+ G R W C
Sbjct: 1482 VGCVDTRAGNCFLETHDRGDSGISCSAEIGVGVTRASCC--CSLG-RAWGNPCELCPMAN 1538
Query: 713 ------------------------DVDECLE-PNVCANGDCSNLEGSYMCSCHKGYTRTP 747
D+DEC E P +C GDC N GS+ C C GY +
Sbjct: 1539 TTEYRTLCPGGEGFQPNRITVILEDIDECQELPGLCQGGDCVNTFGSFQCECPPGYHLSE 1598
Query: 748 DHKHCRDIDECQ-QGNLCVNGQCKNTEGSFRCTCGQGYQLSAAKDQCEDIDE-------- 798
+ C DIDEC +C G C NT G++ C C Y + C D+ +
Sbjct: 1599 HTRICEDIDECSTHSGICGPGTCYNTLGNYTCVCPAEYLQVNGGNNCMDMRKSVCFRHYN 1658
Query: 799 --CQH-------RHLCAH----GQCRNT---------EGSFQCVCDQGYRASGLGDHCE- 835
CQ+ R +C GQ N +Q +C G +A G
Sbjct: 1659 GTCQNELAFNVTRKMCCCSYNIGQAWNRPCEACPTPISPDYQILC--GNQAPGFLTDIHT 1716
Query: 836 ----DINECLEDKSVCQRGDCINTAGSYDCTCPDGFQLDDNK-TCQDINEC---EHPGLC 887
DI+EC E ++C G CIN GS+ C CP GF + C+D++EC E P C
Sbjct: 1717 GKPLDIDECGEIPAICANGICINQIGSFRCECPAGFNYNSILLACEDVDECGSRESP--C 1774
Query: 888 GPQGECLNTEGSFHCVCQQGFSISADGRTCEDIDECVNNTVCDSHGFCDNTAGSFRCLCY 947
+C+N GS+ C C +G+ +S G C +EC SHG C +T GS+ CLC+
Sbjct: 1775 QQNADCINIPGSYRCKCTRGYKLSPGG-ACVGRNECREIPNVCSHGDCMDTEGSYMCLCH 1833
Query: 948 QGFQAPQDGQGCVDVNECELLSGVCGEAFCENVEGSFLCVCADENQEYSPMTGQCRSRTS 1007
+GFQA D C+D++EC+ CG C+N+ GS+ C+C G C
Sbjct: 1834 RGFQASADQTLCMDIDECDRQP--CGNGTCKNIIGSYNCLCFPGF--VVTHNGDC----- 1884
Query: 1008 TDLDVDVDQPKEEKKECYYNLNDASLCDNVLAPNVTKQECCCTSGAGWGDNCEIFPCPVL 1067
VD D+ C ++ C T+G+ F C
Sbjct: 1885 ----VDFDE-----------------CTTLVGQVCRFGHCLNTAGS--------FHCLCQ 1915
Query: 1068 GTAEFTEMCPKGKGFVPAGESSSEAGGENYKDADECLLFGQEICKNGFCLNTRPGYECYC 1127
E T A G+N D +ECL C G C N + C C
Sbjct: 1916 DGFELT------------------ADGKNCVDTNECLSLAGT-CLPGTCQNLEGSFRCIC 1956
Query: 1128 KQGTYYDPVKLQCFDMDEC-QDPSSCIDGQCVNTEGSYNCFCTHPMVLDASEKRCIRPAE 1186
G + C D+DEC ++P+ C+ G C N+ GS+ C C VL + RC
Sbjct: 1957 PPG--FQVQSDHCIDIDECSEEPNLCLFGTCTNSPGSFQCLCPPGFVLSDNGHRCF---- 2010
Query: 1187 SNEQIEETDVYQDLCWEHLSDEYVCSRPLVGKQTTYTECCCLY--GEAWGMQCALCPLKD 1244
D Q C+ + CS P TT T CCC GE WG C LCP +
Sbjct: 2011 --------DTRQSFCFTRF-EAGKCSVPKAFN-TTKTRCCCSKRPGEGWGDPCELCPQEG 2060
Query: 1245 SDDYAQLCNIPVTGRRQPYGRDALVDFSE------------------QYTPEADPYFIQD 1286
S + +LC P P D+ D +E + E + D
Sbjct: 2061 SAAFQELC--PFGHGAVPGPDDSREDVNECAENPGVCTNGVCVNTDGSFRCECPFGYSLD 2118
Query: 1287 RFLNSFEELQAEECGILNGCENGRCVRVQEGYTCDCFDGYHLDTAKMTCVDVNECDELNN 1346
+ +EC + + C G C V G+ C C DG+ MTC D++EC LN
Sbjct: 2119 --FTGINCVDTDECSVGHPCGQGTCTNVIGGFECACADGFE-PGLMMTCEDIDECS-LNP 2174
Query: 1347 RMSLCKNAKCINTDGSYKCLCLPGYVPSDKPNYCTPLNTALNLEKD 1392
LC +C NT+GSY C C GY + C ++ + ++D
Sbjct: 2175 L--LCA-FRCHNTEGSYLCTCPAGYTLREDGAMCRDVDECADGQQD 2217
Score = 304 bits (778), Expect = 4e-82
Identities = 223/720 (30%), Positives = 293/720 (40%), Gaps = 126/720 (17%)
Query: 548 EINECTVNPDICGAGHCINLPVRYTCICYEGYRFSEQQRKCVDIDECTQVQHLCSQGRCE 607
+ NEC C G C NL + CIC G F Q C+DIDEC++ +LC G C
Sbjct: 1929 DTNECLSLAGTCLPGTCQNLEGSFRCICPPG--FQVQSDHCIDIDECSEEPNLCLFGTCT 1986
Query: 608 NTEGSFLCICPAGFMASEEGTNCIDVDECLRPDVCGEGHCVNTVGAFR------------ 655
N+ GSF C+CP GF+ S+ G C D + G C + AF
Sbjct: 1987 NSPGSFQCLCPPGFVLSDNGHRCFDTRQSFCFTRFEAGKC-SVPKAFNTTKTRCCCSKRP 2045
Query: 656 -------CEYCDSGYRMTQRGRC--------------EDIDECL-NPSTCPDEQCVNSPG 693
CE C + C ED++EC NP C + CVN+ G
Sbjct: 2046 GEGWGDPCELCPQEGSAAFQELCPFGHGAVPGPDDSREDVNECAENPGVCTNGVCVNTDG 2105
Query: 694 SYQCVPCTEG----FRGWNGQCLDVDECLEPNVCANGDCSNLEGSYMCSCHKGYTRTPDH 749
S++C C G F G N C+D DEC + C G C+N+ G + C+C G+
Sbjct: 2106 SFRC-ECPFGYSLDFTGIN--CVDTDECSVGHPCGQGTCTNVIGGFECACADGF-EPGLM 2161
Query: 750 KHCRDIDECQQGNLCVNGQCKNTEGSFRCTCGQGYQLSAAKDQCEDIDECQHRHLCAHG- 808
C DIDEC L +C NTEGS+ CTC GY L C D+DEC H
Sbjct: 2162 MTCEDIDECSLNPLLCAFRCHNTEGSYLCTCPAGYTLREDGAMCRDVDECADGQQDCHAR 2221
Query: 809 --QCRNTEGSFQCVCDQGYRA-SGLGDHCEDINECLEDKSVCQRGDCINTAGSYDCTCPD 865
+C+N G+F CVC G R G G+ C D NEC +C G C+NTAGS+ C C +
Sbjct: 2222 GMECKNLIGTFACVCPPGMRPLPGSGEGCTDDNECHAQPDLCVNGRCVNTAGSFRCDCDE 2281
Query: 866 GFQLDDNKT-CQDINE----------------------------CEHPGLCGPQGECLNT 896
GFQ T C DI + C GP+ E
Sbjct: 2282 GFQPSPTLTECHDIRQGPCFAEVLQTMCRSLSSSSEAVTRAECCCGGGRGWGPRCELCPL 2341
Query: 897 EGS--FHCVCQQGFSISADGRTCEDIDECVNNTVCDSHGFCDNTAGSFRCLCYQGFQAPQ 954
G+ + +C G +A+GR D+DEC +HG C N+ GSFRC C G+
Sbjct: 2342 PGTSAYRKLCPHGSGYTAEGR---DVDECRMLAHLCAHGECINSLGSFRCHCQAGYTPDA 2398
Query: 955 DGQGCVDVNECELLSGVCGEAFCENVEGSFLCVCADENQEYSPMTGQCRSRTSTDLDVDV 1014
C+D++EC + C C+N +GSFLC C + RT DLD
Sbjct: 2399 TATTCLDMDECSQVPKPC-TFLCKNTKGSFLCSCP------RGYLLEEDGRTCKDLD--- 2448
Query: 1015 DQPKEEKKECYYNLNDASLCDNVLA-------PNVTKQECCCTSGAGWGDNCEIFP--CP 1065
+ + C + LC N + P T+ C D C P C
Sbjct: 2449 -ECTSRQHNCQF------LCVNTVGAFTCRCPPGFTQHHQACFDN----DECSAQPGPCG 2497
Query: 1066 VLGTAEFTE---MCPKGKGFVPAGESSSEAGGENYKDADECLLFGQEICKNGFCLNTRPG 1122
G T C +GF + G +D +EC G C++G C N G
Sbjct: 2498 AHGHCHNTPGSFRCECHQGFTLV------SSGHGCEDVNEC--DGPHRCQHG-CQNQLGG 2548
Query: 1123 YECYCKQGTYYDPVKLQCFDMDECQ-DPSSCIDGQCVNTEGSYNCFCTHPMVLDASEKRC 1181
Y C C QG QC D +EC P +C C NT G + C C D + C
Sbjct: 2549 YRCSCPQGFTQHSQWAQCVDENECALSPPTCGSASCRNTLGGFRCVCPSGFDFDQALGGC 2608
Score = 296 bits (758), Expect = 9e-80
Identities = 202/621 (32%), Positives = 269/621 (43%), Gaps = 110/621 (17%)
Query: 590 DIDECTQVQHLCSQGRCENTEGSFLCICPAGFMASEEGTNCIDVDECLRPDVCGEGHCVN 649
D++EC + +C+ G C NT+GSF C CP G+ G NC+D DEC CG+G C N
Sbjct: 2084 DVNECAENPGVCTNGVCVNTDGSFRCECPFGYSLDFTGINCVDTDECSVGHPCGQGTCTN 2143
Query: 650 TVGAFRCEYCDSGYRMTQRGRCEDIDEC-LNPSTCPDEQCVNSPGSYQCVPCTEGF--RG 706
+G F C C G+ CEDIDEC LNP C +C N+ GSY C C G+ R
Sbjct: 2144 VIGGFECA-CADGFEPGLMMTCEDIDECSLNPLLCAF-RCHNTEGSYLCT-CPAGYTLRE 2200
Query: 707 WNGQCLDVDECLE--PNVCANG-DCSNLEGSYMCSCHKGYTRTPDH-KHCRDIDECQ-QG 761
C DVDEC + + A G +C NL G++ C C G P + C D +EC Q
Sbjct: 2201 DGAMCRDVDECADGQQDCHARGMECKNLIGTFACVCPPGMRPLPGSGEGCTDDNECHAQP 2260
Query: 762 NLCVNGQCKNTEGSFRCTCGQGYQLSAAKDQCEDIDECQHRHLCAHGQCRNTEGSFQ--- 818
+LCVNG+C NT GSFRC C +G+Q S +C DI + CR+ S +
Sbjct: 2261 DLCVNGRCVNTAGSFRCDCDEGFQPSPTLTECHDIRQGPCFAEVLQTMCRSLSSSSEAVT 2320
Query: 819 ---CVCDQGYRASGLGDHCE-------------------------DINECLEDKSVCQRG 850
C C G G G CE D++EC +C G
Sbjct: 2321 RAECCCGGG---RGWGPRCELCPLPGTSAYRKLCPHGSGYTAEGRDVDECRMLAHLCAHG 2377
Query: 851 DCINTAGSYDCTCPDGFQLDDNKT-CQDINECEH-PGLCGPQGECLNTEGSFHCVCQQGF 908
+CIN+ GS+ C C G+ D T C D++EC P C C NT+GSF C C +G+
Sbjct: 2378 ECINSLGSFRCHCQAGYTPDATATTCLDMDECSQVPKPC--TFLCKNTKGSFLCSCPRGY 2435
Query: 909 SISADGRTCEDIDECVNNTVCDSHGFCDNTAGSFRCLCYQGFQAPQDGQGCVDVNECELL 968
+ DGRTC+D+DEC + + C NT G+F C C GF Q Q C D +EC
Sbjct: 2436 LLEEDGRTCKDLDECTSRQH-NCQFLCVNTVGAFTCRCPPGFT--QHHQACFDNDECSAQ 2492
Query: 969 SGVCG-EAFCENVEGSFLCVCADENQEYSPMTGQCRSRTSTDLDVDVDQPKEEKKECYYN 1027
G CG C N GSF C C +Q ++ ++ +
Sbjct: 2493 PGPCGAHGHCHNTPGSFRCEC---HQGFTLVSSG------------------------HG 2525
Query: 1028 LNDASLCDNVLAPNVTKQECCCTSGAGWGDNCEIFPCPVLGTAEFTEMCPKGKGFVPAGE 1087
D + CD P+ + C G G C CP+G
Sbjct: 2526 CEDVNECDG---PHRCQHGCQNQLG---GYRCS---------------CPQG-------- 2556
Query: 1088 SSSEAGGENYKDADECLLFGQEICKNGFCLNTRPGYECYCKQGTYYDPVKLQCFDMDECQ 1147
+ + D +EC L C + C NT G+ C C G +D C ++DEC
Sbjct: 2557 FTQHSQWAQCVDENECAL-SPPTCGSASCRNTLGGFRCVCPSGFDFDQALGGCQEVDECA 2615
Query: 1148 DPSSCIDGQCVNTEGSYNCFC 1168
C NT G + C C
Sbjct: 2616 GRRGPCSYSCANTPGGFLCGC 2636
Score = 290 bits (742), Expect = 7e-78
Identities = 173/478 (36%), Positives = 225/478 (47%), Gaps = 44/478 (9%)
Query: 548 EINECTVNPDICGAGHCINLPVRYTCICYEGYRFSEQQRKCVDIDECTQVQHLC-SQG-R 605
+I+EC++NP +C A C N Y C C GY E C D+DEC Q C ++G
Sbjct: 2166 DIDECSLNPLLC-AFRCHNTEGSYLCTCPAGYTLREDGAMCRDVDECADGQQDCHARGME 2224
Query: 606 CENTEGSFLCICPAGFMASE-EGTNCIDVDEC-LRPDVCGEGHCVNTVGAFRCEYCDSGY 663
C+N G+F C+CP G G C D +EC +PD+C G CVNT G+FRC+ CD G+
Sbjct: 2225 CKNLIGTFACVCPPGMRPLPGSGEGCTDDNECHAQPDLCVNGRCVNTAGSFRCD-CDEGF 2283
Query: 664 RMTQR-GRCEDIDECLNPSTCPDEQCVNSPGSYQCVP----CTEGFRGWNGQC------- 711
+ + C DI + + C + S + V C G RGW +C
Sbjct: 2284 QPSPTLTECHDIRQGPCFAEVLQTMCRSLSSSSEAVTRAECCCGGGRGWGPRCELCPLPG 2343
Query: 712 ------------------LDVDEC-LEPNVCANGDCSNLEGSYMCSCHKGYTRTPDHKHC 752
DVDEC + ++CA+G+C N GS+ C C GYT C
Sbjct: 2344 TSAYRKLCPHGSGYTAEGRDVDECRMLAHLCAHGECINSLGSFRCHCQAGYTPDATATTC 2403
Query: 753 RDIDECQQGNLCVNGQCKNTEGSFRCTCGQGYQLSAAKDQCEDIDECQHRHLCAHGQCRN 812
D+DEC Q CKNT+GSF C+C +GY L C+D+DEC R C N
Sbjct: 2404 LDMDECSQVPKPCTFLCKNTKGSFLCSCPRGYLLEEDGRTCKDLDECTSRQHNCQFLCVN 2463
Query: 813 TEGSFQCVCDQGYRASGLGDHCEDINECLEDKSVC-QRGDCINTAGSYDCTCPDGFQL-D 870
T G+F C C G+ C D +EC C G C NT GS+ C C GF L
Sbjct: 2464 TVGAFTCRCPPGFTQHHQA--CFDNDECSAQPGPCGAHGHCHNTPGSFRCECHQGFTLVS 2521
Query: 871 DNKTCQDINECEHPGLCGPQGECLNTEGSFHCVCQQGFSISADGRTCEDIDECVNNTVCD 930
C+D+NEC+ P C Q C N G + C C QGF+ + C D +EC +
Sbjct: 2522 SGHGCEDVNECDGPHRC--QHGCQNQLGGYRCSCPQGFTQHSQWAQCVDENECALSPPTC 2579
Query: 931 SHGFCDNTAGSFRCLCYQGFQAPQDGQGCVDVNECELLSGVCGEAFCENVEGSFLCVC 988
C NT G FRC+C GF Q GC +V+EC G C + C N G FLC C
Sbjct: 2580 GSASCRNTLGGFRCVCPSGFDFDQALGGCQEVDECAGRRGPCSYS-CANTPGGFLCGC 2636
Score = 286 bits (732), Expect = 1e-76
Identities = 211/661 (31%), Positives = 286/661 (43%), Gaps = 124/661 (18%)
Query: 525 PVEVAPEASTSSASQVIAP----------TQVTEINECTVNPDICGAGHCINLPVRYTCI 574
P E+ P+ S+A Q + P ++NEC NP +C G C+N + C
Sbjct: 2052 PCELCPQEG-SAAFQELCPFGHGAVPGPDDSREDVNECAENPGVCTNGVCVNTDGSFRCE 2110
Query: 575 CYEGYRFSEQQRKCVDIDECTQVQHLCSQGRCENTEGSFLCICPAGFMASEEGTNCIDVD 634
C GY CVD DEC+ V H C QG C N G F C C GF T C D+D
Sbjct: 2111 CPFGYSLDFTGINCVDTDECS-VGHPCGQGTCTNVIGGFECACADGFEPGLMMT-CEDID 2168
Query: 635 EC-LRPDVCGEGHCVNTVGAFRCEYCDSGYRMTQRGR-CEDIDECLNPST---CPDEQCV 689
EC L P +C C NT G++ C C +GY + + G C D+DEC + +C
Sbjct: 2169 ECSLNPLLCAF-RCHNTEGSYLCT-CPAGYTLREDGAMCRDVDECADGQQDCHARGMECK 2226
Query: 690 NSPGSYQCVPCTEGFRGWNGQ---CLDVDEC-LEPNVCANGDCSNLEGSYMCSCHKGYTR 745
N G++ CV C G R G C D +EC +P++C NG C N GS+ C C +G+
Sbjct: 2227 NLIGTFACV-CPPGMRPLPGSGEGCTDDNECHAQPDLCVNGRCVNTAGSFRCDCDEGFQP 2285
Query: 746 TPDHKHCRDIDECQQGNLCVNGQCKNTEGSFR------CTCGQGYQLSAAKDQC------ 793
+P C DI + + C++ S C CG G + C
Sbjct: 2286 SPTLTECHDIRQGPCFAEVLQTMCRSLSSSSEAVTRAECCCGGGRGWGPRCELCPLPGTS 2345
Query: 794 ----------------EDIDECQH-RHLCAHGQCRNTEGSFQCVCDQGYRASGLGDHCED 836
D+DEC+ HLCAHG+C N+ GSF+C C GY C D
Sbjct: 2346 AYRKLCPHGSGYTAEGRDVDECRMLAHLCAHGECINSLGSFRCHCQAGYTPDATATTCLD 2405
Query: 837 INECLEDKSVCQRGDCINTAGSYDCTCPDGFQLD-DNKTCQDINEC---EHPGLCGPQGE 892
++EC + C C NT GS+ C+CP G+ L+ D +TC+D++EC +H Q
Sbjct: 2406 MDECSQVPKPCTFL-CKNTKGSFLCSCPRGYLLEEDGRTCKDLDECTSRQH----NCQFL 2460
Query: 893 CLNTEGSFHCVCQQGFSISADGRTCEDIDEC-VNNTVCDSHGFCDNTAGSFRCLCYQGFQ 951
C+NT G+F C C GF+ + C D DEC C +HG C NT GSFRC C+QGF
Sbjct: 2461 CVNTVGAFTCRCPPGFT--QHHQACFDNDECSAQPGPCGAHGHCHNTPGSFRCECHQGFT 2518
Query: 952 APQDGQGCVDVNECELLSGVCGEAFCENVEGSFLCVCADENQEYSPMTGQCRSRTSTDLD 1011
G GC DVNEC+ + C+N G + C C ++S QC
Sbjct: 2519 LVSSGHGCEDVNECDGPHRC--QHGCQNQLGGYRCSCPQGFTQHSQWA-QC--------- 2566
Query: 1012 VDVDQPKEEKKECYYNLNDASLCDNVLAPNVTKQECCCTSGAGWGDNCEIFPCPVLGTAE 1071
++ EC L+P C + G F C
Sbjct: 2567 -------VDENEC------------ALSPPTCGSASCRNTLGG-------FRC------- 2593
Query: 1072 FTEMCPKGKGFVPAGESSSEAGGENYKDADECLLFGQEICKNGFCLNTRPGYECYCKQGT 1131
+CP G F A GG ++ DEC G+ + C NT G+ C C QG
Sbjct: 2594 ---VCPSGFDFDQA------LGG--CQEVDECA--GRRGPCSYSCANTPGGFLCGCPQGY 2640
Query: 1132 Y 1132
+
Sbjct: 2641 F 2641
Score = 267 bits (683), Expect = 5e-71
Identities = 242/922 (26%), Positives = 326/922 (35%), Gaps = 241/922 (26%)
Query: 559 CGAGHCINLPVRYTCICYEGY--------RFSEQQRKCVDIDECTQVQHLCSQGRCENTE 610
CG G C + C C +G R S C++ C LC +G
Sbjct: 90 CGEGFCSQPNL---CTCADGTLAPSCGVSRGSGCSVSCMNGGTCRGASCLCQKGYTGTVC 146
Query: 611 GSFLCICPAGFMASEEGTNCIDVDECLRPDVCG---------------EGHCVNTVGAFR 655
G +C C + C+ P+ C G C VG
Sbjct: 147 GQPIC-----------DRGCHNGGRCIGPNRCACVYGFMGPQCERDYRTGPCFGQVGPEG 195
Query: 656 CEYCDSGYRMTQRGRCEDIDECLNPSTCPDEQCVNSPGSYQCVPCTEGF--RGWNGQCLD 713
C++ +G T+ C + P E C P PC GF G C D
Sbjct: 196 CQHQLTGLVCTKALCCATVGRAWG---LPCELCPAQPH-----PCRRGFIPNIHTGACQD 247
Query: 714 VDECLE-PNVCANGDCSNLEGSYMCSCHKGYTRTPDHKHCRDIDECQQGNLCVNGQCK-N 771
VDEC P +C G C N+ GS+ C C G+ + C D ++ G+C +
Sbjct: 248 VDECQAVPGLCQGGSCVNMVGSFHCRCPVGHRLSDSSAACEDYRAGACFSVLFGGRCAGD 307
Query: 772 TEGSF---RCTCGQG--YQLSAAKDQCEDIDECQHRHLCAH------------------- 807
G + +C C +G + + C + + LCA
Sbjct: 308 LAGHYTRRQCCCDRGRCWAAGPVPELCPPRGSNEFQQLCAQRLPLLPGHPGLFPGLLGFG 367
Query: 808 --------GQCR-NTEGS-FQCVCDQGYRASGLGDHC--EDINECLEDKSVCQRGDCINT 855
G R N GS + + G S +G + I+ C ++C G C+ T
Sbjct: 368 SNGMGPPLGPARLNPHGSDARGIPSLGPGNSNIGTATLNQTIDICRHFTNLCLNGRCLPT 427
Query: 856 AGSYDCTCPDGFQLDDNKTCQDINECE----HPGLC-------------GPQ-------- 890
SY C C G+ D C D++EC H G C G Q
Sbjct: 428 PSSYRCECNVGYTQDVRGECIDVDECTSSPCHHGDCVNIPGTYHCRCYPGFQATPTRQAC 487
Query: 891 ---------------GECLNTEGSFHCVCQQGFSISADGRTCEDIDECVNNTVCDSHGFC 935
G C+NTEGSF CVC GF +S DG+ C D +EC +T+C +G C
Sbjct: 488 VDVDECIVSGGLCHLGRCVNTEGSFQCVCNAGFELSPDGKNCVDHNECATSTMC-VNGVC 546
Query: 936 DNTAGSFRCLCYQGFQAPQDGQGCVDVNECELLSGVCGEAFCENVEGSFLCVCADENQEY 995
N GSF CLC GF G C+D++EC+ G+C C N EGSF C
Sbjct: 547 LNEDGSFSCLCKPGFLLAPGGHYCMDIDECQ-TPGICVNGHCTNTEGSFRC--------- 596
Query: 996 SPMTGQCRSRTSTDLDVDVDQPKEEKKECYYNLNDASLCDNVLAPNVTKQECCCTS-GAG 1054
QC + D V + CY + S C VTK ECCC + G
Sbjct: 597 -----QCLGGLAVGTDGRVCVDTHVRSTCYGAIEKGS-CARPFPGTVTKSECCCANPDHG 650
Query: 1055 WGDNCEIFPCPVLGTAEFTEMCPKGKGFVPAGESSSE----------------------- 1091
+G+ C++ CP +AEF +C G G G +E
Sbjct: 651 FGEPCQL--CPAKDSAEFQALCSSGLGITTDGRDINECALDPEVCANGVCENLRGSYRCV 708
Query: 1092 --------AGGENYKDADECLLFGQEICKNGFCLNTRPGYECYCKQGTYYDPVKLQCFDM 1143
A G++ D DEC L +C NG+C N+ Y C C G ++ C D+
Sbjct: 709 CNLGYEAGASGKDCTDVDECAL-NSLLCDNGWCQNSPGSYSCSCPPGFHFWQDTEICKDV 767
Query: 1144 DECQDPSSCIDGQCVNTEGSYNCFCTHPMVLDASEKRCIRPAESNEQIEETDVYQDLCWE 1203
DEC S C+ G C N GSY C C LD S C+ D + CW
Sbjct: 768 DECLS-SPCVSGVCRNLAGSYTCKCGPGSRLDPSGTFCL------------DSTKGTCWL 814
Query: 1204 HLSDEYVCSRPLVGKQTTYTECCCLYGEAWGMQCALCPLKDSDDYAQLCNIPVTGRRQPY 1263
+ E C L G + +ECC G AWG C C
Sbjct: 815 KI-QESRCEVNLQG-ASLRSECCATLGAAWGSPCERC----------------------- 849
Query: 1264 GRDALVDFSEQYTPEADPYFIQDRFLNSFEELQAEECGILNGCE-------NGRCVRVQE 1316
E DP F + C +N CE NGRCV
Sbjct: 850 --------------EIDP-----ACARGFARMTGVTCDDVNECESFPGVCPNGRCVNTAG 890
Query: 1317 GYTCDCFDGYHLDTAKMTCVDV 1338
+ C+C +G LD + CVDV
Sbjct: 891 SFRCECPEGLMLDASGRLCVDV 912
Score = 228 bits (580), Expect = 4e-59
Identities = 141/407 (34%), Positives = 189/407 (46%), Gaps = 50/407 (12%)
Query: 547 TEINECTVNPDICGAGHCINLPVRYTCICYEGYRFSEQQRKCVDI--------------- 591
T+ NEC PD+C G C+N + C C EG++ S +C DI
Sbjct: 2251 TDDNECHAQPDLCVNGRCVNTAGSFRCDCDEGFQPSPTLTECHDIRQGPCFAEVLQTMCR 2310
Query: 592 ------DECTQVQHLCSQG-----RCE----NTEGSFLCICPAGFMASEEGTNCIDVDEC 636
+ T+ + C G RCE ++ +CP G + EG DVDEC
Sbjct: 2311 SLSSSSEAVTRAECCCGGGRGWGPRCELCPLPGTSAYRKLCPHGSGYTAEGR---DVDEC 2367
Query: 637 -LRPDVCGEGHCVNTVGAFRCEYCDSGYRMTQRG-RCEDIDECLN-PSTCPDEQCVNSPG 693
+ +C G C+N++G+FRC +C +GY C D+DEC P C C N+ G
Sbjct: 2368 RMLAHLCAHGECINSLGSFRC-HCQAGYTPDATATTCLDMDECSQVPKPC-TFLCKNTKG 2425
Query: 694 SYQCVPCTEGF--RGWNGQCLDVDECLEPNVCANGDCSNLEGSYMCSCHKGYTRTPDHKH 751
S+ C C G+ C D+DEC C N G++ C C G+T+ H+
Sbjct: 2426 SFLC-SCPRGYLLEEDGRTCKDLDECTSRQHNCQFLCVNTVGAFTCRCPPGFTQ--HHQA 2482
Query: 752 CRDIDEC--QQGNLCVNGQCKNTEGSFRCTCGQGYQLSAAKDQCEDIDECQHRHLCAHGQ 809
C D DEC Q G +G C NT GSFRC C QG+ L ++ CED++EC H C HG
Sbjct: 2483 CFDNDECSAQPGPCGAHGHCHNTPGSFRCECHQGFTLVSSGHGCEDVNECDGPHRCQHG- 2541
Query: 810 CRNTEGSFQCVCDQGYRASGLGDHCEDINECLEDKSVCQRGDCINTAGSYDCTCPDGFQL 869
C+N G ++C C QG+ C D NEC C C NT G + C CP GF
Sbjct: 2542 CQNQLGGYRCSCPQGFTQHSQWAQCVDENECALSPPTCGSASCRNTLGGFRCVCPSGFDF 2601
Query: 870 DDN-KTCQDINECEHPGLCGP-QGECLNTEGSFHCVCQQGFSISADG 914
D CQ+++EC G GP C NT G F C C QG+ + G
Sbjct: 2602 DQALGGCQEVDEC--AGRRGPCSYSCANTPGGFLCGCPQGYFRAGQG 2646
Score = 211 bits (538), Expect = 3e-54
Identities = 115/292 (39%), Positives = 152/292 (52%), Gaps = 11/292 (3%)
Query: 548 EINECTVNPDICGAGHCINLPVRYTCICYEGYRFSEQQRKCVDIDECTQVQHLCSQGRCE 607
+++EC + +C G CIN + C C GY C+D+DEC+QV C+ C+
Sbjct: 2363 DVDECRMLAHLCAHGECINSLGSFRCHCQAGYTPDATATTCLDMDECSQVPKPCTF-LCK 2421
Query: 608 NTEGSFLCICPAGFMASEEGTNCIDVDECLRPDVCGEGHCVNTVGAFRCEYCDSGYRMTQ 667
NT+GSFLC CP G++ E+G C D+DEC + CVNTVGAF C C G+
Sbjct: 2422 NTKGSFLCSCPRGYLLEEDGRTCKDLDECTSRQHNCQFLCVNTVGAFTCR-CPPGFTQHH 2480
Query: 668 RGRCEDIDEC-LNPSTCPDE-QCVNSPGSYQCVPCTEGFR--GWNGQCLDVDECLEPNVC 723
+ C D DEC P C C N+PGS++C C +GF C DV+EC P+ C
Sbjct: 2481 QA-CFDNDECSAQPGPCGAHGHCHNTPGSFRC-ECHQGFTLVSSGHGCEDVNECDGPHRC 2538
Query: 724 ANGDCSNLEGSYMCSCHKGYTRTPDHKHCRDIDECQQGN-LCVNGQCKNTEGSFRCTCGQ 782
+G C N G Y CSC +G+T+ C D +EC C + C+NT G FRC C
Sbjct: 2539 QHG-CQNQLGGYRCSCPQGFTQHSQWAQCVDENECALSPPTCGSASCRNTLGGFRCVCPS 2597
Query: 783 GYQLSAAKDQCEDIDECQHRHLCAHGQCRNTEGSFQCVCDQGYRASGLGDHC 834
G+ A C+++DEC R C NT G F C C QGY +G G HC
Sbjct: 2598 GFDFDQALGGCQEVDECAGRRGPCSYSCANTPGGFLCGCPQGYFRAGQG-HC 2648
Score = 125 bits (315), Expect = 2e-28
Identities = 64/167 (38%), Positives = 86/167 (51%), Gaps = 8/167 (4%)
Query: 550 NECTVNPDICGA-GHCINLPVRYTCICYEGYRFSEQQRKCVDIDECTQVQHLCSQGRCEN 608
+EC+ P CGA GHC N P + C C++G+ C D++EC H C G C+N
Sbjct: 2487 DECSAQPGPCGAHGHCHNTPGSFRCECHQGFTLVSSGHGCEDVNECDG-PHRCQHG-CQN 2544
Query: 609 TEGSFLCICPAGFMASEEGTNCIDVDEC-LRPDVCGEGHCVNTVGAFRCEYCDSGYRMTQ 667
G + C CP GF + C+D +EC L P CG C NT+G FRC C SG+ Q
Sbjct: 2545 QLGGYRCSCPQGFTQHSQWAQCVDENECALSPPTCGSASCRNTLGGFRC-VCPSGFDFDQ 2603
Query: 668 R-GRCEDIDECLNPSTCPDEQCVNSPGSYQCVPCTEG-FRGWNGQCL 712
G C+++DEC C N+PG + C C +G FR G C+
Sbjct: 2604 ALGGCQEVDECAGRRGPCSYSCANTPGGFLC-GCPQGYFRAGQGHCV 2649
Score = 116 bits (290), Expect = 2e-25
Identities = 149/644 (23%), Positives = 209/644 (32%), Gaps = 155/644 (24%)
Query: 768 QCKNTEGS-FRCTCGQGYQLSAAKDQCEDIDECQHRHLCAHGQCRNTEGSFQCVCDQGY- 825
Q N GS F C G++ + QC + C R C G C C C G
Sbjct: 55 QGPNVCGSRFHAYCCPGWRTFPGRSQCV-VPIC--RRACGEGFCSQPN---LCTCADGTL 108
Query: 826 -------RASGLGDHCEDINECLEDKSVCQRGDCINTAGSYDCTCPDGFQLDDNKTCQDI 878
R SG C + C +CQ+G G C ++ C +
Sbjct: 109 APSCGVSRGSGCSVSCMNGGTCRGASCLCQKGYTGTVCGQPIC----------DRGCHNG 158
Query: 879 NECEHPGLC-------GPQGEC-LNTEGSFHCVCQQGFSISADGRTCEDIDECVNNTVCD 930
C P C GPQ E T F V +G G C C TV
Sbjct: 159 GRCIGPNRCACVYGFMGPQCERDYRTGPCFGQVGPEGCQHQLTGLVCTKALCCA--TVGR 216
Query: 931 SHGFCDNTAGSFRCLCYQGFQAPQDGQGCVDVNECELLSGVCGEAFCENVEGSFLCVCAD 990
+ G + C +GF C DV+EC+ + G+C C N+ GSF C C
Sbjct: 217 AWGLPCELCPAQPHPCRRGFIPNIHTGACQDVDECQAVPGLCQGGSCVNMVGSFHCRC-P 275
Query: 991 ENQEYSPMTGQCRSRTSTDLDVDVDQPKEEKKECYYNLNDASLCDNVLAPNVTKQECCCT 1050
S + C ++ + +++ C LA + T+++CCC
Sbjct: 276 VGHRLSDSSAAC---------------EDYRAGACFSVLFGGRCAGDLAGHYTRRQCCCD 320
Query: 1051 SGAGWGDNCEIFPCPVLGTAEFTEMC---------------------------------- 1076
G W CP G+ EF ++C
Sbjct: 321 RGRCWAAGPVPELCPPRGSNEFQQLCAQRLPLLPGHPGLFPGLLGFGSNGMGPPLGPARL 380
Query: 1077 -PKG---KGFVPAGESSSEAGGENYKDADECLLFGQEICKNGFCLNTRPGYECYCKQGTY 1132
P G +G G +S G + +C NG CL T Y C C G Y
Sbjct: 381 NPHGSDARGIPSLGPGNSNIGTATLNQTIDICRHFTNLCLNGRCLPTPSSYRCECNVG-Y 439
Query: 1133 YDPVKLQCFDMDECQDPSSCIDGQCVNTEGSYNCFCTHPMVLDASEKRCIRPAESNEQIE 1192
V+ +C D+DEC S C G CVN G+Y+C C + + C+ ++
Sbjct: 440 TQDVRGECIDVDECTS-SPCHHGDCVNIPGTYHCRCYPGFQATPTRQACV-------DVD 491
Query: 1193 ETDVYQDLCWEHL--------SDEYVCS---------RPLVGKQTTYTECCCLYGEAWGM 1235
E V LC HL S + VC+ + V T C+ G
Sbjct: 492 ECIVSGGLC--HLGRCVNTEGSFQCVCNAGFELSPDGKNCVDHNECATSTMCVNG----- 544
Query: 1236 QCALCPLKDSDDYAQLCNIPVTGRRQPYGRDALVDFSEQYTPEADPYFIQDRFLNSFEEL 1295
+C L + ++ LC G G +D E TP
Sbjct: 545 ---VC-LNEDGSFSCLCK---PGFLLAPGGHYCMDIDECQTP------------------ 579
Query: 1296 QAEECGILNGCENGRCVRVQEGYTCDCFDGYHLDTAKMTCVDVN 1339
GI C NG C + + C C G + T CVD +
Sbjct: 580 -----GI---CVNGHCTNTEGSFRCQCLGGLAVGTDGRVCVDTH 615
Score = 115 bits (287), Expect = 4e-25
Identities = 54/132 (40%), Positives = 76/132 (57%), Gaps = 10/132 (7%)
Query: 286 CLPGYKRV--NNTFCQDINECQLQ-GVCPNGECLNTMGSYRCTCKIGFGPDPTFSSCVPD 342
C PG + + + C D NEC Q +C NG C+NT GS+RC C GF P PT + C
Sbjct: 2236 CPPGMRPLPGSGEGCTDDNECHAQPDLCVNGRCVNTAGSFRCDCDEGFQPSPTLTECH-- 2293
Query: 343 PPVISEEKGPCY-RLVSSGRQCMHPLSVHLTKQLCCCSVGKAWGPHCEKCPLPGTAAFKE 401
+GPC+ ++ + + + S +T+ CCC G+ WGP CE CPLPGT+A+++
Sbjct: 2294 ----DIRQGPCFAEVLQTMCRSLSSSSEAVTRAECCCGGGRGWGPRCELCPLPGTSAYRK 2349
Query: 402 ICPGGMGYTVSG 413
+CP G GYT G
Sbjct: 2350 LCPHGSGYTAEG 2361
Score = 101 bits (251), Expect = 6e-21
Identities = 128/550 (23%), Positives = 176/550 (32%), Gaps = 158/550 (28%)
Query: 884 PGLCGPQGECLNTEGSFHCVCQQGFSISADGRTCEDIDECVNNTVCD---SHGFCDNTAG 940
P +CG + FH C G+ RT +CV +C GFC
Sbjct: 57 PNVCGSR---------FHAYCCPGW------RTFPGRSQCVV-PICRRACGEGFCSQPN- 99
Query: 941 SFRCLCYQGFQAPQDGQG--------CVDVNECELLSGVCGEAFCENVEGSFLCVCADEN 992
C C G AP G C++ C S +C + + V G +C N
Sbjct: 100 --LCTCADGTLAPSCGVSRGSGCSVSCMNGGTCRGASCLCQKGYTGTVCGQPICDRGCHN 157
Query: 993 QEYSPMTGQCRSRTSTDLDVDVDQPKEEKK----ECYYNLNDASLCDNVLAPNVTKQECC 1048
G+C P+ E+ C+ + + TK CC
Sbjct: 158 G------GRCIGPNRCACVYGFMGPQCERDYRTGPCFGQVGPEGCQHQLTGLVCTKALCC 211
Query: 1049 CTSGAGWGDNCEIFPCPVLGTAEFTEMCPKGKGFVPAGESSSEAGGENYKDADECLLFGQ 1108
T G WG CE+ P
Sbjct: 212 ATVGRAWGLPCELCPAQ------------------------------------------P 229
Query: 1109 EICKNGFCLNTRPGYECYCKQGTYYDPVKLQCFDMDECQD-PSSCIDGQCVNTEGSYNCF 1167
C+ GF N G C D+DECQ P C G CVN GS++C
Sbjct: 230 HPCRRGFIPNIHTG----------------ACQDVDECQAVPGLCQGGSCVNMVGSFHCR 273
Query: 1168 CTHPMVLDASEKRCIRPAESNEQIEETDVYQDLCWEHLSDEYVCSRPLVGKQTTYTECCC 1227
C L S C D C+ L C+ L G T +CCC
Sbjct: 274 CPVGHRLSDSSAAC------------EDYRAGACFSVLFGGR-CAGDLAGHYTR-RQCCC 319
Query: 1228 LYGEAW--GMQCALCPLKDSDDYAQLC--NIPVT------------------------GR 1259
G W G LCP + S+++ QLC +P+ R
Sbjct: 320 DRGRCWAAGPVPELCPPRGSNEFQQLCAQRLPLLPGHPGLFPGLLGFGSNGMGPPLGPAR 379
Query: 1260 RQPYGRDALVDFSEQYTPEADP--YFIQDRFLNSFEELQAEECGILNGCENGRCVRVQEG 1317
P+G DA + P P I LN ++ N C NGRC+
Sbjct: 380 LNPHGSDA------RGIPSLGPGNSNIGTATLNQTIDICRH---FTNLCLNGRCLPTPSS 430
Query: 1318 YTCDCFDGYHLDTAKMTCVDVNECDELNNRMSLCKNAKCINTDGSYKCLCLPGYVPSDKP 1377
Y C+C GY D + C+DV+EC S C + C+N G+Y C C PG+ +
Sbjct: 431 YRCECNVGYTQDV-RGECIDVDECTS-----SPCHHGDCVNIPGTYHCRCYPGFQATPTR 484
Query: 1378 NYCTPLNTAL 1387
C ++ +
Sbjct: 485 QACVDVDECI 494
Score = 91.7 bits (226), Expect = 5e-18
Identities = 177/777 (22%), Positives = 239/777 (30%), Gaps = 210/777 (27%)
Query: 720 PNVCANGDCSNLEGSYMCSCHKGYTRTPDHKHC------RDIDE--CQQGNLCVNGQCKN 771
PNVC + + C G+ P C R E C Q NLC C
Sbjct: 57 PNVCGS--------RFHAYCCPGWRTFPGRSQCVVPICRRACGEGFCSQPNLCT---C-- 103
Query: 772 TEGSFRCTCGQGYQLSAAKDQCEDIDECQHRHLCAHGQCRNTEGSFQCVCDQGYRASGLG 831
+G+ +CG + S C + G CR C+C +GY + G
Sbjct: 104 ADGTLAPSCGVS-RGSGCSVSCMN-----------GGTCRGAS----CLCQKGYTGTVCG 147
Query: 832 DHCEDINECLEDKSVCQRGDCINTA---GSYDCTCPDGFQLD----DNKTCQDINE---- 880
+ +C RG C N G C C GF D +T +
Sbjct: 148 ------------QPICDRG-CHNGGRCIGPNRCACVYGFMGPQCERDYRTGPCFGQVGPE 194
Query: 881 -CEHP--GLCGPQGECLNTEG---SFHCV--------CQQGFSISADGRTCEDIDECVNN 926
C+H GL + C T G C C++GF + C+D+DEC
Sbjct: 195 GCQHQLTGLVCTKALCCATVGRAWGLPCELCPAQPHPCRRGFIPNIHTGACQDVDECQAV 254
Query: 927 TVCDSHGFCDNTAGSFRCLCYQGFQAPQDGQGCVDVNECELLSGVCGEAFCENVEGSFLC 986
G C N GSF C C G + C D S + G ++ G +
Sbjct: 255 PGLCQGGSCVNMVGSFHCRCPVGHRLSDSSAACEDYRAGACFSVLFGGRCAGDLAGHYTR 314
Query: 987 --VCADENQEYS--PMTGQCRSRTSTDLDVDVDQPKEEKKECYYNLNDASLCDNVLAPNV 1042
C D + ++ P+ C R S + LC L P +
Sbjct: 315 RQCCCDRGRCWAAGPVPELCPPRGSNEFQ--------------------QLCAQRL-PLL 353
Query: 1043 TKQECCCTSGAGWGDNCEIFPCPVLGTAEFTEMCPKGKGFVPAGESSSEAGGENYKDADE 1102
G+G N P LG A +G G +S G +
Sbjct: 354 PGHPGLFPGLLGFGSNGM---GPPLGPARLNPHGSDARGIPSLGPGNSNIGTATLNQTID 410
Query: 1103 CLLFGQEICKNGFCLNTRPGYECYCKQGTYYDPVKLQCFDMDECQDP------------- 1149
+C NG CL T Y C C G Y V+ +C D+DEC
Sbjct: 411 ICRHFTNLCLNGRCLPTPSSYRCECNVG-YTQDVRGECIDVDECTSSPCHHGDCVNIPGT 469
Query: 1150 ---------------SSCID-------------GQCVNTEGSYNCFCTHPMVLDASEKRC 1181
+C+D G+CVNTEGS+ C C L K C
Sbjct: 470 YHCRCYPGFQATPTRQACVDVDECIVSGGLCHLGRCVNTEGSFQCVCNAGFELSPDGKNC 529
Query: 1182 IRPAESNEQ--------IEETDVYQDLC---------WEHLSDEYVCSRP--LVGKQTTY 1222
+ E + E + LC + D C P V T
Sbjct: 530 VDHNECATSTMCVNGVCLNEDGSFSCLCKPGFLLAPGGHYCMDIDECQTPGICVNGHCTN 589
Query: 1223 TE----CCCLYGEAWGMQCALCPLKD--SDDYAQL----CNIPVTGRRQPYGRDALVDFS 1272
TE C CL G A G +C S Y + C P G V S
Sbjct: 590 TEGSFRCQCLGGLAVGTDGRVCVDTHVRSTCYGAIEKGSCARPFPGT---------VTKS 640
Query: 1273 EQYTPEADPYFIQDRFLNSFEELQAEECGILNGCENGRCVRVQEGYTCDCFDGYHLDTAK 1332
E D F E C + ++ + C G + T
Sbjct: 641 ECCCANPDHGF-------------GEPCQLCPAKDSAE-------FQALCSSGLGITTDG 680
Query: 1333 MTCVDVNECDELNNRMSLCKNAKCINTDGSYKCLCLPGYVPSDKPNYCTPLN-TALN 1388
D+NEC +C N C N GSY+C+C GY CT ++ ALN
Sbjct: 681 R---DINECAL---DPEVCANGVCENLRGSYRCVCNLGYEAGASGKDCTDVDECALN 731
Score = 91.3 bits (225), Expect = 6e-18
Identities = 64/237 (27%), Positives = 102/237 (43%), Gaps = 47/237 (19%)
Query: 228 TQLGRCFQET-----IGSQCGKALPGLSKQEDCCGTVGTSWGFNKCQKCPKKPSYHGYNQ 282
T+ G CF ET G C + + CC ++G +WG N C+ CP + Y
Sbjct: 1487 TRAGNCFLETHDRGDSGISCSAEIGVGVTRASCCCSLGRAWG-NPCELCPMANTTE-YRT 1544
Query: 283 MMECLPGYKRVNNT-FCQDINECQ-LQGVCPNGECLNTMGSYRCTCKIGFGPDPTFSSCV 340
+ G++ T +DI+ECQ L G+C G+C+NT GS++C C G+ C
Sbjct: 1545 LCPGGEGFQPNRITVILEDIDECQELPGLCQGGDCVNTFGSFQCECPPGYHLSEHTRIC- 1603
Query: 341 PDPPVISEEKGPC-------------------YRLVSSGRQCM----------------H 365
D S G C Y V+ G CM +
Sbjct: 1604 EDIDECSTHSGICGPGTCYNTLGNYTCVCPAEYLQVNGGNNCMDMRKSVCFRHYNGTCQN 1663
Query: 366 PLSVHLTKQLCCCS--VGKAWGPHCEKCPLPGTAAFKEICPGGMGYTVSGVHRRRPI 420
L+ ++T+++CCCS +G+AW CE CP P + ++ +C ++ +H +P+
Sbjct: 1664 ELAFNVTRKMCCCSYNIGQAWNRPCEACPTPISPDYQILCGNQAPGFLTDIHTGKPL 1720
Score = 87.8 bits (216), Expect = 7e-17
Identities = 54/153 (35%), Positives = 70/153 (45%), Gaps = 7/153 (4%)
Query: 548 EINECTVNPDICGAGHCINLPVRYTCICYEGYRFSEQQRKCVDIDECTQVQHLCSQGRCE 607
++NEC P C G C N Y C C +G+ Q +CVD +EC C C
Sbjct: 2528 DVNECD-GPHRCQHG-CQNQLGGYRCSCPQGFTQHSQWAQCVDENECALSPPTCGSASCR 2585
Query: 608 NTEGSFLCICPAGFMASEEGTNCIDVDECL-RPDVCGEGHCVNTVGAFRCEYCDSGYRMT 666
NT G F C+CP+GF + C +VDEC R C C NT G F C C GY
Sbjct: 2586 NTLGGFRCVCPSGFDFDQALGGCQEVDECAGRRGPCSYS-CANTPGGFLCG-CPQGYFRA 2643
Query: 667 QRGRC-EDIDECLNPSTCPD-EQCVNSPGSYQC 697
+G C + P PD E+ ++S Y+C
Sbjct: 2644 GQGHCVSGLGFSPGPQDTPDKEELLSSEACYEC 2676
Score = 83.6 bits (205), Expect = 1e-15
Identities = 46/126 (36%), Positives = 65/126 (51%), Gaps = 11/126 (8%)
Query: 286 CLPGYKRVNNTFCQDINECQLQ-GVCPNGECLNTMGSYRCTCKIGFGPDPTFSSCVPDPP 344
C PG++ V + C DI+EC + +C G C N+ GS++C C GF C
Sbjct: 1956 CPPGFQ-VQSDHCIDIDECSEEPNLCLFGTCTNSPGSFQCLCPPGFVLSDNGHRC----- 2009
Query: 345 VISEEKGPCYRLVSSGRQCMHPLSVHLTKQLCCCSV--GKAWGPHCEKCPLPGTAAFKEI 402
+ C+ +G+ C P + + TK CCCS G+ WG CE CP G+AAF+E+
Sbjct: 2010 -FDTRQSFCFTRFEAGK-CSVPKAFNTTKTRCCCSKRPGEGWGDPCELCPQEGSAAFQEL 2067
Query: 403 CPGGMG 408
CP G G
Sbjct: 2068 CPFGHG 2073
Score = 73.9 bits (180), Expect = 1e-12
Identities = 42/127 (33%), Positives = 68/127 (53%), Gaps = 12/127 (9%)
Query: 231 GRCFQETIGSQC---GKALPGLSKQEDCCGTVGTSWGFNKCQKCPKKPSYHGYNQMMECL 287
G CF E + + C + +++ E CCG G WG +C+ CP P Y ++
Sbjct: 2298 GPCFAEVLQTMCRSLSSSSEAVTRAECCCGG-GRGWG-PRCELCPL-PGTSAYRKLCPHG 2354
Query: 288 PGYKRVNNTFCQDINECQ-LQGVCPNGECLNTMGSYRCTCKIGFGPDPTFSSCVPDPPVI 346
GY +D++EC+ L +C +GEC+N++GS+RC C+ G+ PD T ++C+ D
Sbjct: 2355 SGYTAEG----RDVDECRMLAHLCAHGECINSLGSFRCHCQAGYTPDATATTCL-DMDEC 2409
Query: 347 SEEKGPC 353
S+ PC
Sbjct: 2410 SQVPKPC 2416
Score = 71.6 bits (174), Expect = 5e-12
Identities = 61/219 (27%), Positives = 82/219 (37%), Gaps = 38/219 (17%)
Query: 692 PGSYQCV------PCTEGFRGWNGQCLDVDECLEPNV-----------CANGDCSNLEGS 734
PG QCV C EGF C D L P+ C NG
Sbjct: 76 PGRSQCVVPICRRACGEGFCSQPNLCTCADGTLAPSCGVSRGSGCSVSCMNGGTCR---G 132
Query: 735 YMCSCHKGYTRTPDHKHCRDIDECQQGNLCVN-GQCKNTEGSFRCTCGQGYQLSAAKDQC 793
C C KGYT T + D C G C+ +C G C + Y+ Q
Sbjct: 133 ASCLCQKGYTGTVCGQPICDRG-CHNGGRCIGPNRCACVYGFMGPQCERDYRTGPCFGQV 191
Query: 794 EDIDECQHRH---LCAHGQCRNTEG---SFQCV--------CDQGYRASGLGDHCEDINE 839
+ CQH+ +C C T G C C +G+ + C+D++E
Sbjct: 192 GP-EGCQHQLTGLVCTKALCCATVGRAWGLPCELCPAQPHPCRRGFIPNIHTGACQDVDE 250
Query: 840 CLEDKSVCQRGDCINTAGSYDCTCPDGFQLDDNK-TCQD 877
C +CQ G C+N GS+ C CP G +L D+ C+D
Sbjct: 251 CQAVPGLCQGGSCVNMVGSFHCRCPVGHRLSDSSAACED 289
Score = 71.6 bits (174), Expect = 5e-12
Identities = 35/108 (32%), Positives = 51/108 (47%), Gaps = 19/108 (17%)
Query: 545 QVTEINECTVNPDICGAGHCINLPVRYTCICYEGYRFSEQQRKCVDIDECTQVQHLCSQG 604
Q + NEC ++P CG+ C N + C+C G+ F + C ++DEC + CS
Sbjct: 2565 QCVDENECALSPPTCGSASCRNTLGGFRCVCPSGFDFDQALGGCQEVDECAGRRGPCSYS 2624
Query: 605 RCENTEGSFLCICPAGFMASEEGTNCIDVDECLRPDVCGEGHCVNTVG 652
C NT G FLC CP G+ + G+GHCV+ +G
Sbjct: 2625 -CANTPGGFLCGCPQGYFRA------------------GQGHCVSGLG 2653
Score = 70.5 bits (171), Expect = 1e-11
Identities = 38/115 (33%), Positives = 56/115 (48%), Gaps = 5/115 (4%)
Query: 229 QLGRCFQETIGSQCGKALPGLSKQEDCCGTVGTSWGFNKCQKCPKKPSYHGYNQMMECLP 288
+L CF +CG LPG + + CC ++G WG +C+ CP S + L
Sbjct: 913 RLEPCFLRWDEDECGVTLPGKYRMDVCCCSIGAVWGV-ECEACPDPESLEFASLCPRGLG 971
Query: 289 GYKR---VNNTFCQDINECQL-QGVCPNGECLNTMGSYRCTCKIGFGPDPTFSSC 339
R F +D+NEC++ G+C +G C NT+GS+ C C GF D +C
Sbjct: 972 FASRDFLSGRPFYKDVNECKVFPGLCTHGTCRNTVGSFHCACAGGFALDAQERNC 1026
Score = 58.2 bits (139), Expect = 6e-08
Identities = 86/370 (23%), Positives = 120/370 (32%), Gaps = 93/370 (25%)
Query: 32 PSICKVTCTKGSCQNSC--EKGNTTTLISENG---HAADTLTATNFRVVICHLP-----C 81
P++C TC G+ SC +G+ ++ NG A L + +C P C
Sbjct: 98 PNLC--TCADGTLAPSCGVSRGSGCSVSCMNGGTCRGASCLCQKGYTGTVCGQPICDRGC 155
Query: 82 MNGGQCSSRDKCQCPPNFTGKLCQI-----PVHGASVPKLYQHSQQPG----KALGTHVI 132
NGG+C ++C C F G C+ P G P+ QH Q G KAL +
Sbjct: 156 HNGGRCIGPNRCACVYGFMGPQCERDYRTGPCFGQVGPEGCQH-QLTGLVCTKALCCATV 214
Query: 133 HSTHTLPLTVTSQQGVKVK--FPPNIVNIHVKHPPEASVQIHQVSRIDGPTGQKTKEAQP 190
LP + Q + F PNI + E +A P
Sbjct: 215 GRAWGLPCELCPAQPHPCRRGFIPNIHTGACQDVDEC-------------------QAVP 255
Query: 191 GQSQVSYQGLPVQKTQTIHSTYSHQQVIPHVYPVAAKTQLGRCFQETIGSQCGKALPGLS 250
G Q G V + H + + G CF G +C L G
Sbjct: 256 GLCQ---GGSCVNMVGSFHCRCPVGHRLSDSSAACEDYRAGACFSVLFGGRCAGDLAGHY 312
Query: 251 KQEDCCGTVGTSWGFNKC-QKCPKKPSYHGYN---QMMECLPGY---------------- 290
+ CC G W + CP + S Q + LPG+
Sbjct: 313 TRRQCCCDRGRCWAAGPVPELCPPRGSNEFQQLCAQRLPLLPGHPGLFPGLLGFGSNGMG 372
Query: 291 -----KRVN---------------------NTFCQDINECQ-LQGVCPNGECLNTMGSYR 323
R+N T Q I+ C+ +C NG CL T SYR
Sbjct: 373 PPLGPARLNPHGSDARGIPSLGPGNSNIGTATLNQTIDICRHFTNLCLNGRCLPTPSSYR 432
Query: 324 CTCKIGFGPD 333
C C +G+ D
Sbjct: 433 CECNVGYTQD 442
Score = 58.2 bits (139), Expect = 6e-08
Identities = 39/117 (33%), Positives = 57/117 (48%), Gaps = 7/117 (5%)
Query: 228 TQLGRCFQETIGSQCG--KALPGLSKQEDCCGT-VGTSWGFNKCQKCPKKPSYHGYNQMM 284
T+ CF +C KA +K CC G WG + C+ CP++ S + ++
Sbjct: 2012 TRQSFCFTRFEAGKCSVPKAF-NTTKTRCCCSKRPGEGWG-DPCELCPQEGSA-AFQELC 2068
Query: 285 ECLPGYKRVNNTFCQDINEC-QLQGVCPNGECLNTMGSYRCTCKIGFGPDPTFSSCV 340
G + +D+NEC + GVC NG C+NT GS+RC C G+ D T +CV
Sbjct: 2069 PFGHGAVPGPDDSREDVNECAENPGVCTNGVCVNTDGSFRCECPFGYSLDFTGINCV 2125
Score = 52.8 bits (125), Expect = 2e-06
Identities = 33/124 (26%), Positives = 56/124 (45%), Gaps = 5/124 (4%)
Query: 233 CFQETIGSQCGKALPGLSKQEDCCG-TVGTSWGFNKCQKCPKKPSYHGYNQMMECLPGYK 291
CF+ G+ + ++++ CC +G +W C+ CP S PG+
Sbjct: 1653 CFRHYNGTCQNELAFNVTRKMCCCSYNIGQAWN-RPCEACPTPISPDYQILCGNQAPGFL 1711
Query: 292 R-VNNTFCQDINEC-QLQGVCPNGECLNTMGSYRCTCKIGFGPDPTFSSCVPDPPVISEE 349
++ DI+EC ++ +C NG C+N +GS+RC C GF + +C D
Sbjct: 1712 TDIHTGKPLDIDECGEIPAICANGICINQIGSFRCECPAGFNYNSILLAC-EDVDECGSR 1770
Query: 350 KGPC 353
+ PC
Sbjct: 1771 ESPC 1774
Score = 52.8 bits (125), Expect = 2e-06
Identities = 53/202 (26%), Positives = 80/202 (39%), Gaps = 37/202 (18%)
Query: 237 TIGSQCGKALPGLSKQEDCCGTVGTSWGFNKCQKCPKKPSYHGY------NQMMECLPGY 290
T+G+ + PG ++ C + ++C P HG+ + EC G+
Sbjct: 2464 TVGAFTCRCPPGFTQHHQAC------FDNDECSAQPGPCGAHGHCHNTPGSFRCECHQGF 2517
Query: 291 KRVNNTF-CQDINECQLQGVCPNGECLNTMGSYRCTCKIGFGPDPTFSSCVPD------P 343
V++ C+D+NEC C +G C N +G YRC+C GF ++ CV + P
Sbjct: 2518 TLVSSGHGCEDVNECDGPHRCQHG-CQNQLGGYRCSCPQGFTQHSQWAQCVDENECALSP 2576
Query: 344 PVISEEKGPCYRLVSSGRQCMHPLSVHLTKQLCCCS-----VGKAWGPHCEKCP-LPGTA 397
P R G +C+ P + L C G+ GP C PG
Sbjct: 2577 PTCGSAS---CRNTLGGFRCVCPSGFDFDQALGGCQEVDECAGRR-GPCSYSCANTPG-- 2630
Query: 398 AFKEICP-----GGMGYTVSGV 414
F CP G G+ VSG+
Sbjct: 2631 GFLCGCPQGYFRAGQGHCVSGL 2652
Score = 45.8 bits (107), Expect = 3e-04
Identities = 21/57 (36%), Positives = 30/57 (52%), Gaps = 1/57 (1%)
Query: 285 ECLPGYKRVNNTFCQDINEC-QLQGVCPNGECLNTMGSYRCTCKIGFGPDPTFSSCV 340
+C GYK C NEC ++ VC +G+C++T GSY C C GF + C+
Sbjct: 1790 KCTRGYKLSPGGACVGRNECREIPNVCSHGDCMDTEGSYMCLCHRGFQASADQTLCM 1846
Score = 41.2 bits (95), Expect = 0.007
Identities = 30/111 (27%), Positives = 46/111 (41%), Gaps = 16/111 (14%)
Query: 286 CLPGYKRVNNTFCQDINECQLQGVCPNGECLNTMGSYRCTCKIGFGPDPTFSSCVPDPPV 345
C G++ C+DI+EC L + C NT GSY CTC G+ + C D
Sbjct: 2152 CADGFEPGLMMTCEDIDECSLNPLLCAFRCHNTEGSYLCTCPAGYTLREDGAMC-RDVDE 2210
Query: 346 ISEEKGPCYRLVSSGRQCMHPLSVHLTKQLCCCSVGKAWGPHCEKCPLPGT 396
++ + C+ + G +C + + C C G PLPG+
Sbjct: 2211 CADGQQDCH---ARGMECKNLIGTF----ACVCPPGMR--------PLPGS 2246
Score = 41.2 bits (95), Expect = 0.007
Identities = 22/66 (33%), Positives = 29/66 (43%), Gaps = 4/66 (6%)
Query: 1306 CENGRCVRVQEGYTCDCFDGYHLDTAKMTCVDVNECDELNNRMSLCKNAKCINTDGSYKC 1365
C + C G+ C C G+ D A C +V+EC R C + C NT G + C
Sbjct: 2579 CGSASCRNTLGGFRCVCPSGFDFDQALGGCQEVDEC---AGRRGPC-SYSCANTPGGFLC 2634
Query: 1366 LCLPGY 1371
C GY
Sbjct: 2635 GCPQGY 2640
Score = 39.3 bits (90), Expect = 0.027
Identities = 18/49 (36%), Positives = 22/49 (44%), Gaps = 1/49 (2%)
Query: 285 ECLPGYKR-VNNTFCQDINECQLQGVCPNGECLNTMGSYRCTCKIGFGP 332
EC GY C D +EC + C G C N +G + C C GF P
Sbjct: 2110 ECPFGYSLDFTGINCVDTDECSVGHPCGQGTCTNVIGGFECACADGFEP 2158
Score = 39.3 bits (90), Expect = 0.027
Identities = 45/203 (22%), Positives = 68/203 (33%), Gaps = 51/203 (25%)
Query: 258 TVGTSWGFNKCQKCPKKPSYHGYNQ----MMECLPGYK-RVNNTFCQDINECQLQGVCPN 312
T T ++C + PK ++ N + C GY + C+D++EC +
Sbjct: 2399 TATTCLDMDECSQVPKPCTFLCKNTKGSFLCSCPRGYLLEEDGRTCKDLDECTSRQHNCQ 2458
Query: 313 GECLNTMGSYRCTCKIGF-----------------GPDPTFSSCVPDPPVISEEKGPCYR 355
C+NT+G++ C C GF GP C P E +
Sbjct: 2459 FLCVNTVGAFTCRCPPGFTQHHQACFDNDECSAQPGPCGAHGHCHNTPGSFRCECHQGFT 2518
Query: 356 LVSSG------------RQCMHPLSVHLTKQLCCCSVGKAWGPHCEKC----------PL 393
LVSSG +C H L C C G +C P
Sbjct: 2519 LVSSGHGCEDVNECDGPHRCQHGCQNQLGGYRCSCPQGFTQHSQWAQCVDENECALSPPT 2578
Query: 394 PGTAA-------FKEICPGGMGY 409
G+A+ F+ +CP G +
Sbjct: 2579 CGSASCRNTLGGFRCVCPSGFDF 2601
Score = 37.7 bits (86), Expect = 0.078
Identities = 26/96 (27%), Positives = 44/96 (45%), Gaps = 22/96 (22%)
Query: 241 QCGKALPGLSKQEDCCGTVGTSWGFNKCQKCPKKPSYHGYNQMMECLPGYKRVNNTFCQD 300
+CG+ +P + C +G+ +C+ CP + YN ++ C+D
Sbjct: 1724 ECGE-IPAICANGICINQIGSF----RCE-CP---AGFNYNSILLA-----------CED 1763
Query: 301 INEC-QLQGVCP-NGECLNTMGSYRCTCKIGFGPDP 334
++EC + C N +C+N GSYRC C G+ P
Sbjct: 1764 VDECGSRESPCQQNADCINIPGSYRCKCTRGYKLSP 1799
Score = 35.0 bits (79), Expect = 0.50
Identities = 24/71 (33%), Positives = 30/71 (42%), Gaps = 8/71 (11%)
Query: 32 PSICKVTC--TKGSCQNSCEKGNTTTLISENGHAADTLTATNFRVVICHLPCMNGGQCSS 89
P C C TKGS SC +G L+ E+G L R C C+N +
Sbjct: 2413 PKPCTFLCKNTKGSFLCSCPRGY---LLEEDGRTCKDLDECTSRQHNCQFLCVNTVGAFT 2469
Query: 90 RDKCQCPPNFT 100
C+CPP FT
Sbjct: 2470 ---CRCPPGFT 2477
>gi|66346695 fibrillin 2 precursor [Homo sapiens]
Length = 2912
Score = 472 bits (1215), Expect = e-133
Identities = 288/891 (32%), Positives = 411/891 (46%), Gaps = 128/891 (14%)
Query: 550 NECTVNPDICGAGHCINLPVRYTCICYEGYRFSEQQRKCVDIDECTQVQHLCSQGRCENT 609
NEC P++C G C++L Y CIC+ G++ S+ Q C+D+DEC + H C G C+NT
Sbjct: 1894 NECLEIPNVCSHGLCVDLQGSYQCICHNGFKASQDQTMCMDVDECER--HPCGNGTCKNT 1951
Query: 610 EGSFLCICPAGFMASEEGTNCIDVDECLR--PDVCGEGHCVNTVGAFRCEYCDSGYRMTQ 667
GS+ C+C GF + +C+D+DEC VC G C N +G+F+C C+ GY +T
Sbjct: 1952 VGSYNCLCYPGFELTHNN-DCLDIDECSSFFGQVCRNGRCFNEIGSFKC-LCNEGYELTP 2009
Query: 668 RGR-CEDIDECLN-PSTCPDEQCVNSPGSYQCVPCTEGFRGWNGQCLDVDECLE-PNVCA 724
G+ C D +EC+ P +C C N GS++C+ C G+ + C+D++EC E PN+C
Sbjct: 2010 DGKNCIDTNECVALPGSCSPGTCQNLEGSFRCI-CPPGYEVKSENCIDINECDEDPNICL 2068
Query: 725 NGDCSNLEGSYMCSCHKGYTRTPDHKHCRDIDECQQGNLCVNGQC--------------- 769
G C+N G + C C G+ + + + C D + NG+C
Sbjct: 2069 FGSCTNTPGGFQCLCPPGFVLSDNGRRCFDTRQSFCFTNFENGKCSVPKAFNTTKAKCCC 2128
Query: 770 ----------------KNTEGSFRCTCGQGY-QLSAAKDQCEDIDEC-QHRHLCAHGQCR 811
K+ E +F+ C G+ + + D ED++EC + +C++GQC
Sbjct: 2129 SKMPGEGWGDPCELCPKDDEVAFQDLCPYGHGTVPSLHDTREDVNECLESPGICSNGQCI 2188
Query: 812 NTEGSFQCVCDQGYRASGLGDHCEDINECLEDKSVCQRGDCINTAGSYDCTCPDGFQLDD 871
NT+GSF+C C GY G C D +EC + C G C N GS++C C +GF+
Sbjct: 2189 NTDGSFRCECPMGYNLDYTGVRCVDTDEC-SIGNPCGNGTCTNVIGSFECNCNEGFEPGP 2247
Query: 872 NKTCQDINEC-EHPGLCGPQGECLNTEGSFHCVCQQGFSISADGRTCEDIDECVNNTV-C 929
C+DINEC ++P LC + C+NT GS+ C C G+++ D + C+D+DEC C
Sbjct: 2248 MMNCEDINECAQNPLLCAFR--CMNTFGSYECTCPIGYALREDQKMCKDLDECAEGLHDC 2305
Query: 930 DSHGF-CDNTAGSFRCLCYQGFQAPQDGQGCVDVNECELLSGVCGEAFCENVEGSFLCVC 988
+S G C N G+F C+C G DG+GCVD NEC G+C C N+ GS+ C C
Sbjct: 2306 ESRGMMCKNLIGTFMCICPPGMARRPDGEGCVDENECRTKPGICENGRCVNIIGSYRCEC 2365
Query: 989 ADENQEYSPMTGQCRSRTSTDLDVDVDQPKEEKKECYYNLNDASLCDNVLAPNVTKQECC 1048
+ Q S T +C +V Q + NL VTK ECC
Sbjct: 2366 NEGFQSSSSGT-ECLDNRQGLCFAEVLQTICQMASSSRNL-------------VTKSECC 2411
Query: 1049 CTSGAGWGDNCEIFPCPVLGTAEFTEMCPKGKGFVPAGESSSEAGGENYKDADECLLFGQ 1108
C G GWG CE+ CP+ GTA++ ++CP G G+ G +D DEC +
Sbjct: 2412 CDGGRGWGHQCEL--CPLPGTAQYKKICPHGPGYTTDG-----------RDIDECKVM-P 2457
Query: 1109 EICKNGFCLNTRPGYECYCKQGTYYDPVKLQCFDMDEC-QDPSSCIDGQCVNTEGSYNCF 1167
+C NG C+NT + C+CK G D C D+DEC Q P C + C NTEGSY C
Sbjct: 2458 NLCTNGQCINTMGSFRCFCKVGYTTDISGTSCIDLDECSQSPKPC-NYICKNTEGSYQCS 2516
Query: 1168 CTHPMVLDASEKRCIRPAESNEQIEETDVYQDLCWEHLSDEYVCSRPLVGKQT------T 1221
C VL K C + ++E Q C +++C L G T
Sbjct: 2517 CPRGYVLQEDGKTC-------KDLDECQTKQHNC------QFLCVNTLGGFTCKCPPGFT 2563
Query: 1222 YTECCCLYGEAWGMQCALCPLKD---------SDDYAQLCNIPVTG------------RR 1260
C+ G Q +LC K S + + ++ TG R
Sbjct: 2564 QHHTACIDNNECGSQPSLCGAKGICQNTPGSFSCECQRGFSLDATGLNCEDVDECDGNHR 2623
Query: 1261 QPYGRDALVDFSEQYTPEADPYFIQDRFLNSFEELQAEECGILNGCENGRCVRVQEGYTC 1320
+G ++ P+ +IQ N + EC N C + C Y C
Sbjct: 2624 CQHGCQNILGGYRCGCPQG---YIQHYQWNQC--VDENECSNPNACGSASCYNTLGSYKC 2678
Query: 1321 DCFDGYHLDTAKMTCVDVNECDELNNRMSLCKNAKCINTDGSYKCLCLPGY 1371
C G+ D C DVNEC N N C NT+G Y C C PGY
Sbjct: 2679 ACPSGFSFDQFSSACHDVNECSSSKNPC----NYGCSNTEGGYLCGCPPGY 2725
Score = 437 bits (1123), Expect = e-122
Identities = 308/994 (30%), Positives = 419/994 (42%), Gaps = 232/994 (23%)
Query: 548 EINECTVNPDICGAGHCINLPVRYTCICYEGYRFSEQQRKCVDIDECTQ---VQHLCSQG 604
+I+EC VN +C G C N P Y+C C GY F + C DI+EC V C
Sbjct: 810 DIDECLVNRLLCDNGLCRNTPGSYSCTCPPGYVFRTETETCEDINECESNPCVNGACRNN 869
Query: 605 ----RCENTEGS------FLCI-------------------------------------- 616
CE + GS +CI
Sbjct: 870 LGSFNCECSPGSKLSSTGLICIDSLKGTCWLNIQDSRCEVNINGATLKSECCATLGAAWG 929
Query: 617 -----------CPAGFMASEEGTNCIDVDEC-LRPDVCGEGHCVNTVGAFRCEYCDSGYR 664
CP G +A +G C DV+EC + P VC G CVN+ G+F CE C G
Sbjct: 930 SPCERCELDTACPRG-LARIKGVTCEDVNECEVFPGVCPNGRCVNSKGSFHCE-CPEGLT 987
Query: 665 MTQRGR-CEDI-----------DECLNPSTCP---DEQC--VNSPGSYQCVPCTE-GFRG 706
+ GR C DI DEC++P D C V + +C C + G +
Sbjct: 988 LDGTGRVCLDIRMEQCYLKWDEDECIHPVPGKFRMDACCCAVGAAWGTECEECPKPGTKE 1047
Query: 707 WNGQC-------------------LDVDECLE-PNVCANGDCSNLEGSYMCSCHKGYTRT 746
+ C D++EC P +C G C N GS+ C C+ G+
Sbjct: 1048 YETLCPRGAGFANRGDVLTGRPFYKDINECKAFPGMCTYGKCRNTIGSFKCRCNSGFALD 1107
Query: 747 PDHKHCRDIDECQ-QGNLCVNGQCKNTEGSFRCTCGQGYQLS-AAKDQCEDIDECQHRHL 804
+ ++C DIDEC+ +LC +G C NT GSF C C +GY+ C DIDEC+ L
Sbjct: 1108 MEERNCTDIDECRISPDLCGSGICVNTPGSFECECFEGYESGFMMMKNCMDIDECERNPL 1167
Query: 805 -CAHGQCRNTEGSFQCVCDQGYRASGLGDHCEDINECLEDKSVCQRGDCINTAGSYDCTC 863
C G C NTEGSFQC C G+ S + C DINEC ++C+ G C+N G+Y C+C
Sbjct: 1168 LCRGGTCVNTEGSFQCDCPLGHELSPSREDCVDINECSLSDNLCRNGKCVNMIGTYQCSC 1227
Query: 864 PDGFQLD-DNKTCQDINECE-HPGLCGPQGECLNTEGSFHCVCQQGFSISADGRTCEDID 921
G+Q D + C DI+EC G C Q C N+EGS+ C C +G+++ DGR+C DID
Sbjct: 1228 NPGYQATPDRQGCTDIDECMIMNGGCDTQ--CTNSEGSYECSCSEGYALMPDGRSCADID 1285
Query: 922 ECVNNT-VCDSHGFCDNTAGSFRCLCYQGFQAPQDGQGCVDVNECELLSGVCGEAFCENV 980
EC NN +CD G C N G +RCLCY GF A D + C+DVNEC+L S +C CEN
Sbjct: 1286 ECENNPDICDG-GQCTNIPGEYRCLCYDGFMASMDMKTCIDVNECDLNSNICMFGECENT 1344
Query: 981 EGSFLCVCADENQEYSPMTGQCRSRTSTDLD----------------------------- 1011
+GSF+C C YS G + TD+D
Sbjct: 1345 KGSFICHC---QLGYSVKKG---TTGCTDVDECEIGAHNCDMHASCLNIPGSFKCSCREG 1398
Query: 1012 --------VDVDQPKEEKKECYYNLNDASLCDNVLAPNVTKQECCCTSG-AGWGDNC-EI 1061
+D+D+ +C N C N C C+ G G G C ++
Sbjct: 1399 WIGNGIKCIDLDECSNGTHQCSINAQ----CVNTPG----SYRCACSEGFTGDGFTCSDV 1450
Query: 1062 FPCPVLGTAEFTEMCPKGK--------------GFVPAGESSSEAGGENYKDADECLLFG 1107
C AE +C G+ GF PA +S S +D DEC
Sbjct: 1451 DEC-----AENINLCENGQCLNVPGAYRCECEMGFTPASDSRS------CQDIDECSF-- 1497
Query: 1108 QEICKNGFCLNTRPGYECYCKQGTYYDPVKLQCFDMDECQDPSSCIDGQCVNTEGSYNCF 1167
Q IC G C N + C C G D C D+DEC DP +C++G CVNT G Y C
Sbjct: 1498 QNICVFGTCNNLPGMFHCICDDGYELDRTGGNCTDIDECADPINCVNGLCVNTPGRYECN 1557
Query: 1168 CTHPMVLDASEKRCIRPAESNEQIEETDVYQDLCWEHLSDEYVCSRPLVGKQTTYTECCC 1227
C L+ + C+ N ++ + D + +G + + CCC
Sbjct: 1558 CPPDFQLNPTGVGCVDNRVGNCYLK---------FGPRGDGSLSCNTEIGVGVSRSSCCC 1608
Query: 1228 LYGEAWGMQCALCPLKDSDDYAQLCNIPVTGRRQPYGRDALVDFSEQYTPEADPYFIQDR 1287
G+AWG C CP +S +Y LC P G E + P ++D
Sbjct: 1609 SLGKAWGNPCETCPPVNSTEYYTLC---------PGG--------EGFRPNPITIILED- 1650
Query: 1288 FLNSFEELQAEECGILNG-CENGRCVRVQEGYTCDCFDGYHLDTAKMTCVDVNECDELNN 1346
+EC L G C+ G C+ + C+C GY+L C D++EC
Sbjct: 1651 ---------IDECQELPGLCQGGNCINTFGSFQCECPQGYYLSEDTRICEDIDECFA--- 1698
Query: 1347 RMSLCKNAKCINTDGSYKCLCLPGYVPSDKPNYC 1380
+C C NT G+Y C+C P Y+ + + C
Sbjct: 1699 HPGVCGPGTCYNTLGNYTCICPPEYMQVNGGHNC 1732
Score = 426 bits (1096), Expect = e-119
Identities = 283/884 (32%), Positives = 381/884 (43%), Gaps = 155/884 (17%)
Query: 548 EINECTVNPDICGAGHCINLPVRYTCICYEGYRFSEQQRKCVDIDECTQVQHLCSQGRCE 607
+I+EC NPDIC G C N+P Y C+CY+G+ S + C+D++EC ++C G CE
Sbjct: 1283 DIDECENNPDICDGGQCTNIPGEYRCLCYDGFMASMDMKTCIDVNECDLNSNICMFGECE 1342
Query: 608 NTEGSFLCICPAGFMASEEGTNCIDVDEC-LRPDVCG-EGHCVNTVGAFRCEYCDSGYRM 665
NT+GSF+C C G+ + T C DVDEC + C C+N G+F+C C G+ +
Sbjct: 1343 NTKGSFICHCQLGYSVKKGTTGCTDVDECEIGAHNCDMHASCLNIPGSFKCS-CREGW-I 1400
Query: 666 TQRGRCEDIDECLNPS-TCP-DEQCVNSPGSYQCVPCTEGFRGWNGQCLDVDECLEP-NV 722
+C D+DEC N + C + QCVN+PGSY+C C+EGF G C DVDEC E N+
Sbjct: 1401 GNGIKCIDLDECSNGTHQCSINAQCVNTPGSYRCA-CSEGFTGDGFTCSDVDECAENINL 1459
Query: 723 CANGDCSNLEGSYMCSCHKGYTRTPDHKHCRDIDECQQGNLCVNGQCKNTEGSFRCTCGQ 782
C NG C N+ G+Y C C G+T D + C+DIDEC N+CV G C N G F C C
Sbjct: 1460 CENGQCLNVPGAYRCECEMGFTPASDSRSCQDIDECSFQNICVFGTCNNLPGMFHCICDD 1519
Query: 783 GYQLSAAKDQCEDIDECQHRHLCAHGQCRNTEGSFQCVCDQGYRASGLGDHCED--INEC 840
GY+L C DIDEC C +G C NT G ++C C ++ + G C D + C
Sbjct: 1520 GYELDRTGGNCTDIDECADPINCVNGLCVNTPGRYECNCPPDFQLNPTGVGCVDNRVGNC 1579
Query: 841 L------EDKSV---------CQRGDCINTAG----------------SYDCTCPDGFQL 869
D S+ R C + G Y CP G
Sbjct: 1580 YLKFGPRGDGSLSCNTEIGVGVSRSSCCCSLGKAWGNPCETCPPVNSTEYYTLCPGGEGF 1639
Query: 870 DDNK---TCQDINEC-EHPGLCGPQGECLNTEGSFHCVCQQGFSISADGRTCEDIDECVN 925
N +DI+EC E PGLC G C+NT GSF C C QG+ +S D R CEDIDEC
Sbjct: 1640 RPNPITIILEDIDECQELPGLC-QGGNCINTFGSFQCECPQGYYLSEDTRICEDIDECFA 1698
Query: 926 NTVCDSHGFCDNTAGSFRCLCYQGFQAPQDGQGCVDVNECELLSGVCGEAFCENVEGSFL 985
+ G C NT G++ C+C + G C+D+ ++FC
Sbjct: 1699 HPGVCGPGTCYNTLGNYTCICPPEYMQVNGGHNCMDMR----------KSFCYRSYNGTT 1748
Query: 986 CVCADENQEYSPMTGQCRSRTSTDLDVDVDQPKEEKKECYYNLNDASLCDNVLAPNVTKQ 1045
C + E +N+ C
Sbjct: 1749 C----------------------------------ENELPFNVTKRMCC----------- 1763
Query: 1046 ECCCTSGAGWGDNCEIFPCPVLGTAEFTEMCPKGKGFVPAGESSSEAGGENYKDADECLL 1105
C G W CE PCP GTA+F +C G +P G D DEC
Sbjct: 1764 -CTYNVGKAWNKPCE--PCPTPGTADFKTIC----GNIPGFTFDIHTG--KAVDIDECKE 1814
Query: 1106 FGQEICKNGFCLNTRPGYECYCKQGTYYDPVKLQCFDMDECQDPSSCI--DGQCVNTEGS 1163
IC NG C+N + C C G Y+ + L C D+DEC + + + C+N+ GS
Sbjct: 1815 I-PGICANGVCINQIGSFRCECPTGFSYNDLLLVCEDIDECSNGDNLCQRNADCINSPGS 1873
Query: 1164 YNCFCTHPMVLDASEKRCIRPAESNEQIEETDVYQDLCWEHLSDEYVCSRPL-VGKQTTY 1222
Y C C L + C+ + NE +E + VCS L V Q +Y
Sbjct: 1874 YRCECAAGFKL-SPNGACV---DRNECLEIPN--------------VCSHGLCVDLQGSY 1915
Query: 1223 TECCCLYGEAWGMQCALCPLKDSDDYAQLCNIPVTGRRQPYGRDALVDFSEQYTPEADPY 1282
+C C G +C D D+ R P G + Y P
Sbjct: 1916 -QCICHNGFKASQDQTMC--MDVDEC----------ERHPCGNGTCKNTVGSYNCLCYPG 1962
Query: 1283 FIQDRFLNSFEELQAEECGILNG--CENGRCVRVQEGYTCDCFDGYHLDTAKMTCVDVNE 1340
F ++ + L +EC G C NGRC + C C +GY L C+D NE
Sbjct: 1963 F---ELTHNNDCLDIDECSSFFGQVCRNGRCFNEIGSFKCLCNEGYELTPDGKNCIDTNE 2019
Query: 1341 CDELNNRMSLCKNAKCINTDGSYKCLCLPGYVPSDKPNYCTPLN 1384
C L C C N +GS++C+C PGY K C +N
Sbjct: 2020 CVALPGS---CSPGTCQNLEGSFRCICPPGY--EVKSENCIDIN 2058
Score = 422 bits (1086), Expect = e-118
Identities = 293/903 (32%), Positives = 403/903 (44%), Gaps = 137/903 (15%)
Query: 549 INECTVNPDICGAGHCINLPVRYTCICYEGYRFSEQQRKCVDIDECTQVQHLCSQGRCEN 608
I+ C + ++C G CI Y C C GY+ + C+D+DECT + C+ G C N
Sbjct: 495 IDICKHHANLCLNGRCIPTVSSYRCECNMGYK-QDANGDCIDVDECT--SNPCTNGDCVN 551
Query: 609 TEGSFLCICPAGFMASEEGTNCIDVDECLRPDV-CGEGHCVNTVGAFRCEYCDSGYRMTQ 667
T GS+ C C AGF + CID+DEC++ V C G CVNT G+F+C C++G+ +T
Sbjct: 552 TPGSYYCKCHAGFQRTPTKQACIDIDECIQNGVLCKNGRCVNTDGSFQC-ICNAGFELTT 610
Query: 668 RGR-CEDIDECLNPSTCPDEQCVNSPGSYQCVPCTEGF-RGWNGQ-CLDVDECLEPNVCA 724
G+ C D DEC + C + C+N GS++C+ C GF NG+ C DVDEC P +C
Sbjct: 611 DGKNCVDHDECTTTNMCLNGMCINEDGSFKCI-CKPGFVLAPNGRYCTDVDECQTPGICM 669
Query: 725 NGDCSNLEGSYMCSCHKGYTRTPDHKHCRDI---DECQQG---NLCVN---GQCKNTEGS 775
NG C N EGS+ C C G D + C D C G +CV G +E
Sbjct: 670 NGHCINSEGSFRCDCPPGLAVGMDGRVCVDTHMRSTCYGGIKKGVCVRPFPGAVTKSE-- 727
Query: 776 FRCTC-------GQGYQLSAAKDQCE----------------DIDECQ-HRHLCAHGQCR 811
C C G+ Q AK+ E DI+EC +CA+G C
Sbjct: 728 --CCCANPDYGFGEPCQPCPAKNSAEFHGLCSSGVGITVDGRDINECALDPDICANGICE 785
Query: 812 NTEGSFQCVCDQGYRASGLGDHCEDINECLEDKSVCQRGDCINTAGSYDCTCPDGFQL-D 870
N GS++C C+ GY G +C DI+ECL ++ +C G C NT GSY CTCP G+
Sbjct: 786 NLRGSYRCNCNSGYEPDASGRNCIDIDECLVNRLLCDNGLCRNTPGSYSCTCPPGYVFRT 845
Query: 871 DNKTCQDINECE-HPGLCGPQGECLNTEGSFHCVCQQGFSISADGRTCEDI--------- 920
+ +TC+DINECE +P + G C N GSF+C C G +S+ G C D
Sbjct: 846 ETETCEDINECESNPCV---NGACRNNLGSFNCECSPGSKLSSTGLICIDSLKGTCWLNI 902
Query: 921 --DEC-VNNTVCDSHGFCDNTAGSF------RC----LCYQGFQAPQDGQGCVDVNECEL 967
C VN C T G+ RC C +G A G C DVNECE+
Sbjct: 903 QDSRCEVNINGATLKSECCATLGAAWGSPCERCELDTACPRGL-ARIKGVTCEDVNECEV 961
Query: 968 LSGVCGEAFCENVEGSFLCVCADENQEYSPMTGQCRSRTSTDLDVDVDQPKEEKKECYYN 1027
GVC C N +GSF C C + +T R D+ ++ +CY
Sbjct: 962 FPGVCPNGRCVNSKGSFHCECPE------GLTLDGTGRVCLDIRME---------QCYLK 1006
Query: 1028 LNDASLCDNVLAPNVTKQECCCTSGAGWGDNCEIFPCPVLGTAEFTEMCPKGKGFVPAGE 1087
D C + + CCC GA WG CE CP GT E+ +CP+G GF G+
Sbjct: 1007 W-DEDECIHPVPGKFRMDACCCAVGAAWGTECE--ECPKPGTKEYETLCPRGAGFANRGD 1063
Query: 1088 SSSEAGGENYKDADECLLFGQEICKNGFCLNTRPGYECYCKQGTYYDPVKLQCFDMDECQ 1147
+ G YKD +EC F +C G C NT ++C C G D + C D+DEC+
Sbjct: 1064 VLT--GRPFYKDINECKAF-PGMCTYGKCRNTIGSFKCRCNSGFALDMEERNCTDIDECR 1120
Query: 1148 -DPSSCIDGQCVNTEGSYNCFCTHPMVLD-ASEKRCIRPAESNEQIEETDVYQDLC---- 1201
P C G CVNT GS+ C C K C+ I+E + LC
Sbjct: 1121 ISPDLCGSGICVNTPGSFECECFEGYESGFMMMKNCM-------DIDECERNPLLCRGGT 1173
Query: 1202 WEHLSDEYVCSRPLVGKQTTYTECCCLYGEAWGMQCALCPLKDSDDYAQLCNIPVTGRRQ 1261
+ + C PL + + E C E C L D+ LC
Sbjct: 1174 CVNTEGSFQCDCPLGHELSPSREDCVDINE--------CSLSDN-----LCR-------- 1212
Query: 1262 PYGRDALVDFSEQYTPEADPYFIQDRFLNSFEELQAEECGILNGCENGRCVRVQEGYTCD 1321
V+ Y +P + ++ +EC I+NG + +C + Y C
Sbjct: 1213 ---NGKCVNMIGTYQCSCNPGYQATPDRQGCTDI--DECMIMNGGCDTQCTNSEGSYECS 1267
Query: 1322 CFDGYHLDTAKMTCVDVNECDELNNRMSLCKNAKCINTDGSYKCLCLPGYVPSDKPNYCT 1381
C +GY L +C D++EC+ N +C +C N G Y+CLC G++ S C
Sbjct: 1268 CSEGYALMPDGRSCADIDECE---NNPDICDGGQCTNIPGEYRCLCYDGFMASMDMKTCI 1324
Query: 1382 PLN 1384
+N
Sbjct: 1325 DVN 1327
Score = 414 bits (1064), Expect = e-115
Identities = 283/852 (33%), Positives = 384/852 (45%), Gaps = 158/852 (18%)
Query: 578 GYRFSEQQRKCVDIDECTQVQHLCSQGRCENTEGSFLCICPAGFMASEEGTNCIDVDECL 637
G+ F K VDIDEC ++ +C+ G C N GSF C CP GF ++ C D+DEC
Sbjct: 1796 GFTFDIHTGKAVDIDECKEIPGICANGVCINQIGSFRCECPTGFSYNDLLLVCEDIDECS 1855
Query: 638 RPD-VCGEG-HCVNTVGAFRCEYCDSGYRMTQRGRCEDIDECLN-PSTCPDEQCVNSPGS 694
D +C C+N+ G++RCE C +G++++ G C D +ECL P+ C CV+ GS
Sbjct: 1856 NGDNLCQRNADCINSPGSYRCE-CAAGFKLSPNGACVDRNECLEIPNVCSHGLCVDLQGS 1914
Query: 695 YQCVPCTEGFRGWNGQ--CLDVDECLEPNVCANGDCSNLEGSYMCSCHKGYTRTPDHKHC 752
YQC+ C GF+ Q C+DVDEC E + C NG C N GSY C C+ G+ T ++ C
Sbjct: 1915 YQCI-CHNGFKASQDQTMCMDVDEC-ERHPCGNGTCKNTVGSYNCLCYPGFELTHNND-C 1971
Query: 753 RDIDECQQ--GNLCVNGQCKNTEGSFRCTCGQGYQLSAAKDQCEDIDECQHRH-LCAHGQ 809
DIDEC G +C NG+C N GSF+C C +GY+L+ C D +EC C+ G
Sbjct: 1972 LDIDECSSFFGQVCRNGRCFNEIGSFKCLCNEGYELTPDGKNCIDTNECVALPGSCSPGT 2031
Query: 810 CRNTEGSFQCVCDQGYRASGLGDHCEDINECLEDKSVCQRGDCINTAGSYDCTCPDGFQL 869
C+N EGSF+C+C GY ++C DINEC ED ++C G C NT G + C CP GF L
Sbjct: 2032 CQNLEGSFRCICPPGYEVKS--ENCIDINECDEDPNICLFGSCTNTPGGFQCLCPPGFVL 2089
Query: 870 DDN-KTCQDINE-----------CEHP------------------GLCGPQGEC-LNTEG 898
DN + C D + C P G P C + E
Sbjct: 2090 SDNGRRCFDTRQSFCFTNFENGKCSVPKAFNTTKAKCCCSKMPGEGWGDPCELCPKDDEV 2149
Query: 899 SFHCVCQQGF-SISADGRTCEDIDECVNNTVCDSHGFCDNTAGSFRCLCYQGFQAPQDGQ 957
+F +C G ++ + T ED++EC+ + S+G C NT GSFRC C G+ G
Sbjct: 2150 AFQDLCPYGHGTVPSLHDTREDVNECLESPGICSNGQCINTDGSFRCECPMGYNLDYTGV 2209
Query: 958 GCVDVNECELLSGVCGEAFCENVEGSFLCVCADENQEYSPMTGQCRSRTSTDLDVDVDQP 1017
CVD +EC + CG C NV GSF C C +E E PM C
Sbjct: 2210 RCVDTDECSI-GNPCGNGTCTNVIGSFECNC-NEGFEPGPMMN-C--------------- 2251
Query: 1018 KEEKKECYYN-LNDASLCDNVLAPNVTKQECCCTSGAGWGDNCEIFPCPVLGTAEFTEMC 1076
E+ EC N L A C N EC C G E +MC
Sbjct: 2252 -EDINECAQNPLLCAFRCMNTFG----SYECTCPIG--------------YALREDQKMC 2292
Query: 1077 PKGKGFVPAGESSSEAGGENYKDADECLLFGQEICKNG--FCLNTRPGYECYCKQGTYYD 1134
KD DEC G C++ C N + C C G
Sbjct: 2293 ---------------------KDLDECAE-GLHDCESRGMMCKNLIGTFMCICPPGMARR 2330
Query: 1135 PVKLQCFDMDECQD-PSSCIDGQCVNTEGSYNCFCTHPMVLDASEKRCIRPAESNEQIEE 1193
P C D +EC+ P C +G+CVN GSY C C +S C+ ++ + +
Sbjct: 2331 PDGEGCVDENECRTKPGICENGRCVNIIGSYRCECNEGFQSSSSGTECL---DNRQGLCF 2387
Query: 1194 TDVYQDLCWEHLSDEYVCSRPLVGKQTTYTECCCLYGEAWGMQCALCPLKDSDDYAQLCN 1253
+V Q +C S SR LV K +ECCC G WG QC LCPL + Y ++C
Sbjct: 2388 AEVLQTICQMASS-----SRNLVTK----SECCCDGGRGWGHQCELCPLPGTAQYKKIC- 2437
Query: 1254 IPVTGRRQPYGRDALVDFSEQYTPEADPYFIQDRFLNSFEELQAEECGIL-NGCENGRCV 1312
P+G D + +EC ++ N C NG+C+
Sbjct: 2438 --------PHGPGYTTDGRD-----------------------IDECKVMPNLCTNGQCI 2466
Query: 1313 RVQEGYTCDCFDGYHLDTAKMTCVDVNECDELNNRMSLCKNAKCINTDGSYKCLCLPGYV 1372
+ C C GY D + +C+D++EC + N C NT+GSY+C C GYV
Sbjct: 2467 NTMGSFRCFCKVGYTTDISGTSCIDLDECSQSPKPC----NYICKNTEGSYQCSCPRGYV 2522
Query: 1373 PSDKPNYCTPLN 1384
+ C L+
Sbjct: 2523 LQEDGKTCKDLD 2534
Score = 409 bits (1051), Expect = e-113
Identities = 282/895 (31%), Positives = 384/895 (42%), Gaps = 164/895 (18%)
Query: 547 TEINECTVNPDICGAGHCINLPVRYTCICYEGYRFSEQQRKCVDIDECTQVQHLCSQGRC 606
T+I+EC + C C N Y C C EGY R C DIDEC +C G+C
Sbjct: 1241 TDIDECMIMNGGCDT-QCTNSEGSYECSCSEGYALMPDGRSCADIDECENNPDICDGGQC 1299
Query: 607 ENTEGSFLCICPAGFMASEEGTNCIDVDEC-LRPDVCGEGHCVNTVGAFRCEYCDSGYRM 665
N G + C+C GFMAS + CIDV+EC L ++C G C NT G+F C +C GY +
Sbjct: 1300 TNIPGEYRCLCYDGFMASMDMKTCIDVNECDLNSNICMFGECENTKGSFIC-HCQLGYSV 1358
Query: 666 TQRGR-CEDIDEC-LNPSTCP-DEQCVNSPGSYQCVPCTEGFRGWNGQCLDVDECLE-PN 721
+ C D+DEC + C C+N PGS++C C EG+ G +C+D+DEC +
Sbjct: 1359 KKGTTGCTDVDECEIGAHNCDMHASCLNIPGSFKC-SCREGWIGNGIKCIDLDECSNGTH 1417
Query: 722 VCA-NGDCSNLEGSYMCSCHKGYTRTPDHKHCRDIDECQQG-NLCVNGQCKNTEGSFRCT 779
C+ N C N GSY C+C +G+T D C D+DEC + NLC NGQC N G++RC
Sbjct: 1418 QCSINAQCVNTPGSYRCACSEGFTG--DGFTCSDVDECAENINLCENGQCLNVPGAYRCE 1475
Query: 780 CGQGYQLSAAKDQCEDIDECQHRHLCAHGQCRNTEGSFQCVCDQGYRASGLGDHCEDINE 839
C G+ ++ C+DIDEC +++C G C N G F C+CD GY G +C DI+E
Sbjct: 1476 CEMGFTPASDSRSCQDIDECSFQNICVFGTCNNLPGMFHCICDDGYELDRTGGNCTDIDE 1535
Query: 840 CLEDKSVCQRGDCINTAGSYDCTCPDGFQLDDNKT-CQDINECEHPGLC----GPQGE-- 892
C D C G C+NT G Y+C CP FQL+ C D G C GP+G+
Sbjct: 1536 CA-DPINCVNGLCVNTPGRYECNCPPDFQLNPTGVGCVD----NRVGNCYLKFGPRGDGS 1590
Query: 893 -CLNTE-----GSFHCVCQQGFSISADGRTC---------------------------ED 919
NTE C C G + TC ED
Sbjct: 1591 LSCNTEIGVGVSRSSCCCSLGKAWGNPCETCPPVNSTEYYTLCPGGEGFRPNPITIILED 1650
Query: 920 IDECVNNTVCDSHGFCDNTAGSFRCLCYQGFQAPQDGQGCVDVNECELLSGVCGEAFCEN 979
IDEC G C NT GSF+C C QG+ +D + C D++EC GVCG C N
Sbjct: 1651 IDECQELPGLCQGGNCINTFGSFQCECPQGYYLSEDTRICEDIDECFAHPGVCGPGTCYN 1710
Query: 980 VEGSFLCVCADENQEYSPMTGQCRSRTSTDLDVDVDQPKEEKKECYYNLNDASLCDNVLA 1039
G++ C+C E Y + G D+ K CY + N + C+N L
Sbjct: 1711 TLGNYTCICPPE---YMQVNG---GHNCMDM---------RKSFCYRSYNGTT-CENELP 1754
Query: 1040 PNVTKQECCCTSGAG--WGDNCEIFPCPVLGTAEFTEMCPKGKGFVPAGESSSEAGGENY 1097
NVTK+ CCCT G W CE PCP GTA+F +C G +P
Sbjct: 1755 FNVTKRMCCCTYNVGKAWNKPCE--PCPTPGTADFKTIC----GNIP------------- 1795
Query: 1098 KDADECLLFGQEICKNGFCLNTRPGYECYCKQGTYYDPVKLQCFDMDECQD-PSSCIDGQ 1156
GF + G + D+DEC++ P C +G
Sbjct: 1796 ----------------GFTFDIHTG----------------KAVDIDECKEIPGICANGV 1823
Query: 1157 CVNTEGSYNCFCTHPMVLDASEKRCIRPAESNEQIEETDVYQDLCWEHLSDEYVCSRPLV 1216
C+N GS+ C C + C E I+E +LC + +
Sbjct: 1824 CINQIGSFRCECPTGFSYNDLLLVC-------EDIDECSNGDNLCQRNAD--------CI 1868
Query: 1217 GKQTTYTECCCLYGEAWGMQCALCPLKDSDDYAQLCNIPVTGRRQPYGRDALVDFSEQYT 1276
+Y C C G A + + +C+ VD Y
Sbjct: 1869 NSPGSY-RCECAAGFKLSPNGACVDRNECLEIPNVCS-----------HGLCVDLQGSYQ 1916
Query: 1277 PEADPYF--IQDRFLNSFEELQAEECGILNGCENGRCVRVQEGYTCDCFDGYHLDTAKMT 1334
F QD+ + + +EC + C NG C Y C C+ G+ L T
Sbjct: 1917 CICHNGFKASQDQTMC----MDVDECE-RHPCGNGTCKNTVGSYNCLCYPGFEL-THNND 1970
Query: 1335 CVDVNECDELNNRMSLCKNAKCINTDGSYKCLCLPGYVPSDKPNYCTPLNTALNL 1389
C+D++EC ++ C+N +C N GS+KCLC GY + C N + L
Sbjct: 1971 CLDIDECSSFFGQV--CRNGRCFNEIGSFKCLCNEGYELTPDGKNCIDTNECVAL 2023
Score = 392 bits (1006), Expect = e-108
Identities = 278/918 (30%), Positives = 388/918 (42%), Gaps = 190/918 (20%)
Query: 547 TEINECTVNPDICGAGHCINLPVRYTCICYEGYRFSEQQRKCVDIDECTQVQHLCSQGRC 606
++++EC N ++C G C+N+P Y C C G+ + R C DIDEC+ Q++C G C
Sbjct: 1448 SDVDECAENINLCENGQCLNVPGAYRCECEMGFTPASDSRSCQDIDECS-FQNICVFGTC 1506
Query: 607 ENTEGSFLCICPAGFMASEEGTNCIDVDECLRPDVCGEGHCVNTVGAFRCEYCDSGYRMT 666
N G F CIC G+ G NC D+DEC P C G CVNT G + C C +++
Sbjct: 1507 NNLPGMFHCICDDGYELDRTGGNCTDIDECADPINCVNGLCVNTPGRYECN-CPPDFQLN 1565
Query: 667 QRG-RCED--IDEC---------------------LNPSTC----------PDEQC--VN 690
G C D + C ++ S+C P E C VN
Sbjct: 1566 PTGVGCVDNRVGNCYLKFGPRGDGSLSCNTEIGVGVSRSSCCCSLGKAWGNPCETCPPVN 1625
Query: 691 SPGSYQCVPCTEGFRGWNGQCL--DVDECLE-PNVCANGDCSNLEGSYMCSCHKGYTRTP 747
S Y P EGFR + D+DEC E P +C G+C N GS+ C C +GY +
Sbjct: 1626 STEYYTLCPGGEGFRPNPITIILEDIDECQELPGLCQGGNCINTFGSFQCECPQGYYLSE 1685
Query: 748 DHKHCRDIDEC-QQGNLCVNGQCKNTEGSFRCTCGQGYQLSAAKDQCEDIDE-------- 798
D + C DIDEC +C G C NT G++ C C Y C D+ +
Sbjct: 1686 DTRICEDIDECFAHPGVCGPGTCYNTLGNYTCICPPEYMQVNGGHNCMDMRKSFCYRSYN 1745
Query: 799 ---CQH-------RHLCAH----GQCRN-------TEGS--FQCVCDQ--GYRASGLGDH 833
C++ + +C G+ N T G+ F+ +C G+
Sbjct: 1746 GTTCENELPFNVTKRMCCCTYNVGKAWNKPCEPCPTPGTADFKTICGNIPGFTFDIHTGK 1805
Query: 834 CEDINECLEDKSVCQRGDCINTAGSYDCTCPDGFQLDDNK-TCQDINECEH-PGLCGPQG 891
DI+EC E +C G CIN GS+ C CP GF +D C+DI+EC + LC
Sbjct: 1806 AVDIDECKEIPGICANGVCINQIGSFRCECPTGFSYNDLLLVCEDIDECSNGDNLCQRNA 1865
Query: 892 ECLNTEGSFHCVCQQGFSISADGRTCEDIDECVNNTVCDSHGFCDNTAGSFRCLCYQGFQ 951
+C+N+ GS+ C C GF +S +G C D +EC+ SHG C + GS++C+C+ GF+
Sbjct: 1866 DCINSPGSYRCECAAGFKLSPNG-ACVDRNECLEIPNVCSHGLCVDLQGSYQCICHNGFK 1924
Query: 952 APQDGQGCVDVNECELLSGVCGEAFCENVEGSFLCVCADENQEYSPMTGQCRSRTSTDLD 1011
A QD C+DV+ECE CG C+N GS+ C+C G + + LD
Sbjct: 1925 ASQDQTMCMDVDECE--RHPCGNGTCKNTVGSYNCLC---------YPGFELTHNNDCLD 1973
Query: 1012 VDVDQPKEEKKECYYNLNDASLCDNVLAPN-VTKQECCCTSGAGWGDNCEIFPCPVLGTA 1070
+D EC +C N N + +C C G
Sbjct: 1974 ID---------ECSSFFGQ--VCRNGRCFNEIGSFKCLCNEGY----------------- 2005
Query: 1071 EFTEMCPKGKGFVPAGESSSEAGGENYKDADECLLFGQEICKNGFCLNTRPGYECYCKQG 1130
E+ P GK + D +EC+ C G C N + C C G
Sbjct: 2006 ---ELTPDGKNCI---------------DTNECVALPGS-CSPGTCQNLEGSFRCICPPG 2046
Query: 1131 TYYDPVKLQCFDMDEC-QDPSSCIDGQCVNTEGSYNCFCTHPMVLDASEKRCIRPAESNE 1189
Y+ C D++EC +DP+ C+ G C NT G + C C VL + +RC
Sbjct: 2047 --YEVKSENCIDINECDEDPNICLFGSCTNTPGGFQCLCPPGFVLSDNGRRCF------- 2097
Query: 1190 QIEETDVYQDLCWEHLSDEYVCSRPLVGKQTTYTECCC--LYGEAWGMQCALCPLKDSDD 1247
D Q C+ + + CS P TT +CCC + GE WG C LCP D
Sbjct: 2098 -----DTRQSFCFTNFENGK-CSVPKAFN-TTKAKCCCSKMPGEGWGDPCELCPKDDEVA 2150
Query: 1248 YAQLCNIPVTGRRQPYGRDALVDFSEQYTPEADPYFIQDRFLNSFEELQAEECGILNG-C 1306
+ LC PYG + + T E EC G C
Sbjct: 2151 FQDLC---------PYGHGTVPSLHD--TRE-----------------DVNECLESPGIC 2182
Query: 1307 ENGRCVRVQEGYTCDCFDGYHLDTAKMTCVDVNECDELNNRMSLCKNAKCINTDGSYKCL 1366
NG+C+ + C+C GY+LD + CVD +EC N C N C N GS++C
Sbjct: 2183 SNGQCINTDGSFRCECPMGYNLDYTGVRCVDTDECSIGNP----CGNGTCTNVIGSFECN 2238
Query: 1367 CLPGYVPSDKPNYCTPLN 1384
C G+ P N C +N
Sbjct: 2239 CNEGFEPGPMMN-CEDIN 2255
Score = 379 bits (973), Expect = e-104
Identities = 290/953 (30%), Positives = 404/953 (42%), Gaps = 173/953 (18%)
Query: 545 QVTEINECTVNPDICGAGHCINLPVRYTCICYEGYRFSEQQRKCVDIDECTQVQHLCSQG 604
+ +I+EC P IC G CIN + C C G+ +++ C DIDEC+ +LC +
Sbjct: 1805 KAVDIDECKEIPGICANGVCINQIGSFRCECPTGFSYNDLLLVCEDIDECSNGDNLCQRN 1864
Query: 605 R-CENTEGSFLCICPAGFMASEEGTNCIDVDECLR-PDVCGEGHCVNTVGAFRCEYCDSG 662
C N+ GS+ C C AGF S G C+D +ECL P+VC G CV+ G+++C C +G
Sbjct: 1865 ADCINSPGSYRCECAAGFKLSPNGA-CVDRNECLEIPNVCSHGLCVDLQGSYQC-ICHNG 1922
Query: 663 YRMTQ-RGRCEDIDECLNPSTCPDEQCVNSPGSYQCVPCTEGFR-GWNGQCLDVDECLE- 719
++ +Q + C D+DEC C + C N+ GSY C+ C GF N CLD+DEC
Sbjct: 1923 FKASQDQTMCMDVDEC-ERHPCGNGTCKNTVGSYNCL-CYPGFELTHNNDCLDIDECSSF 1980
Query: 720 -PNVCANGDCSNLEGSYMCSCHKGYTRTPDHKHCRDIDEC-QQGNLCVNGQCKNTEGSFR 777
VC NG C N GS+ C C++GY TPD K+C D +EC C G C+N EGSFR
Sbjct: 1981 FGQVCRNGRCFNEIGSFKCLCNEGYELTPDGKNCIDTNECVALPGSCSPGTCQNLEGSFR 2040
Query: 778 CTCGQGYQLSAAKDQCEDIDEC-QHRHLCAHGQCRNTEGSFQCVCDQGYRASGLGDHCED 836
C C GY++ + + C DI+EC + ++C G C NT G FQC+C G+ S G C D
Sbjct: 2041 CICPPGYEVKS--ENCIDINECDEDPNICLFGSCTNTPGGFQCLCPPGFVLSDNGRRCFD 2098
Query: 837 INE--CLE--DKSVCQRGDCINTAGSYDC--------------TCPDGFQLDDNKTC--- 875
+ C + C NT + C CP ++ C
Sbjct: 2099 TRQSFCFTNFENGKCSVPKAFNTTKAKCCCSKMPGEGWGDPCELCPKDDEVAFQDLCPYG 2158
Query: 876 -----------QDINEC-EHPGLCGPQGECLNTEGSFHCVCQQGFSISADGRTCEDIDEC 923
+D+NEC E PG+C G+C+NT+GSF C C G+++ G C D DEC
Sbjct: 2159 HGTVPSLHDTREDVNECLESPGICS-NGQCINTDGSFRCECPMGYNLDYTGVRCVDTDEC 2217
Query: 924 VNNTVCDSHGFCDNTAGSFRCLCYQGFQAPQDGQGCVDVNECELLSGVCGEAF-CENVEG 982
C +G C N GSF C C +GF+ P C D+NEC +C AF C N G
Sbjct: 2218 SIGNPC-GNGTCTNVIGSFECNCNEGFE-PGPMMNCEDINECAQNPLLC--AFRCMNTFG 2273
Query: 983 SFLCV-------------------CADENQEYSPMTGQCRSRTSTDLDV----DVDQPKE 1019
S+ C CA+ + C++ T + + +P
Sbjct: 2274 SYECTCPIGYALREDQKMCKDLDECAEGLHDCESRGMMCKNLIGTFMCICPPGMARRPDG 2333
Query: 1020 E----KKECYYNLNDASLCDNVLAPNVT-KQECCCTSG---AGWGDNC-----EIFPCPV 1066
E + EC +C+N N+ C C G + G C + V
Sbjct: 2334 EGCVDENEC---RTKPGICENGRCVNIIGSYRCECNEGFQSSSSGTECLDNRQGLCFAEV 2390
Query: 1067 LGTAEFTEMCPKGKGFVPAGESSSEAGGENYKDADECLLFG----QEICKNG-------- 1114
L T +M + V E + G + C L G ++IC +G
Sbjct: 2391 LQT--ICQMASSSRNLVTKSECCCDGGRGWGHQCELCPLPGTAQYKKICPHGPGYTTDGR 2448
Query: 1115 ---------------FCLNTRPGYECYCKQGTYYDPVKLQCFDMDEC-QDPSSCIDGQCV 1158
C+NT + C+CK G D C D+DEC Q P C + C
Sbjct: 2449 DIDECKVMPNLCTNGQCINTMGSFRCFCKVGYTTDISGTSCIDLDECSQSPKPC-NYICK 2507
Query: 1159 NTEGSYNCFCTHPMVLDASEKRCIRPAESNEQIEETDVYQDLCWEHLSDEYVCSRPLVG- 1217
NTEGSY C C VL K C + ++E Q C +++C L G
Sbjct: 2508 NTEGSYQCSCPRGYVLQEDGKTC-------KDLDECQTKQHNC------QFLCVNTLGGF 2554
Query: 1218 -----KQTTYTECCCLYGEAWGMQCALCPLKDSDDYAQLC-NIPVTGRRQPYGRDALVDF 1271
T C+ G Q +LC K +C N P
Sbjct: 2555 TCKCPPGFTQHHTACIDNNECGSQPSLCGAKG------ICQNTP---------------- 2592
Query: 1272 SEQYTPEADPYFIQDRFLNSFEELQAEECGILNGCENGRCVRVQEGYTCDCFDGYHLDTA 1331
++ E F D + E++ +EC + C++G C + GY C C GY
Sbjct: 2593 -GSFSCECQRGFSLDATGLNCEDV--DECDGNHRCQHG-CQNILGGYRCGCPQGYIQHYQ 2648
Query: 1332 KMTCVDVNECDELNNRMSLCKNAKCINTDGSYKCLCLPGYVPSDKPNYCTPLN 1384
CVD NEC N C +A C NT GSYKC C G+ + C +N
Sbjct: 2649 WNQCVDENECSNPN----ACGSASCYNTLGSYKCACPSGFSFDQFSSACHDVN 2697
Score = 363 bits (933), Expect = e-100
Identities = 253/816 (31%), Positives = 363/816 (44%), Gaps = 121/816 (14%)
Query: 640 DVCGEGHCVNTVGAFRCEYCDSGYRMTQRGRCEDIDECLNPSTCPDEQCVNSPGSYQCVP 699
++C G C+ TV ++RCE C+ GY+ G C D+DEC + + C + CVN+PGSY C
Sbjct: 503 NLCLNGRCIPTVSSYRCE-CNMGYKQDANGDCIDVDECTS-NPCTNGDCVNTPGSYYC-K 559
Query: 700 CTEGFRGWNGQ--CLDVDECLEPNV-CANGDCSNLEGSYMCSCHKGYTRTPDHKHCRDID 756
C GF+ + C+D+DEC++ V C NG C N +GS+ C C+ G+ T D K+C D D
Sbjct: 560 CHAGFQRTPTKQACIDIDECIQNGVLCKNGRCVNTDGSFQCICNAGFELTTDGKNCVDHD 619
Query: 757 ECQQGNLCVNGQCKNTEGSFRCTCGQGYQLSAAKDQCEDIDECQHRHLCAHGQCRNTEGS 816
EC N+C+NG C N +GSF+C C G+ L+ C D+DECQ +C +G C N+EGS
Sbjct: 620 ECTTTNMCLNGMCINEDGSFKCICKPGFVLAPNGRYCTDVDECQTPGICMNGHCINSEGS 679
Query: 817 FQCVCDQGYRASGLGDHCEDINECLEDKSVCQRGDCIN------TAGSYDCTCPD-GFQL 869
F+C C G G C D + ++G C+ T C PD GF
Sbjct: 680 FRCDCPPGLAVGMDGRVCVDTHMRSTCYGGIKKGVCVRPFPGAVTKSECCCANPDYGF-- 737
Query: 870 DDNKTCQ-------------------------DINECE-HPGLCGPQGECLNTEGSFHCV 903
+ CQ DINEC P +C G C N GS+ C
Sbjct: 738 --GEPCQPCPAKNSAEFHGLCSSGVGITVDGRDINECALDPDICA-NGICENLRGSYRCN 794
Query: 904 CQQGFSISADGRTCEDIDEC-VNNTVCDSHGFCDNTAGSFRCLCYQGFQAPQDGQGCVDV 962
C G+ A GR C DIDEC VN +CD+ G C NT GS+ C C G+ + + C D+
Sbjct: 795 CNSGYEPDASGRNCIDIDECLVNRLLCDN-GLCRNTPGSYSCTCPPGYVFRTETETCEDI 853
Query: 963 NECELLSGVCGEAFCENVEGSFLCVCADENQEYSPMTGQCRSRTSTDLDVDVDQPKEEKK 1022
NECE S C C N GSF C C+ ++ +ST L + +D K
Sbjct: 854 NECE--SNPCVNGACRNNLGSFNCECSPGSK-----------LSSTGL-ICIDSLKGT-- 897
Query: 1023 ECYYNLNDASLCDNVLAPNVTKQECCCTSGAGWGDNCEIFPCPVLGTAEFTEMCPKGKGF 1082
C+ N+ D S C+ + K ECC T GA WG CE E CP+G
Sbjct: 898 -CWLNIQD-SRCEVNINGATLKSECCATLGAAWGSPCE--------RCELDTACPRGLAR 947
Query: 1083 VPAGESSSEAGGENYKDADECLLFGQEICKNGFCLNTRPGYECYCKQGTYYDPVKLQCFD 1142
+ G +D +EC +F +C NG C+N++ + C C +G D C D
Sbjct: 948 IK---------GVTCEDVNECEVF-PGVCPNGRCVNSKGSFHCECPEGLTLDGTGRVCLD 997
Query: 1143 --MDECQ---DPSSCI---------DGQCVNTEGSYNCFCTHPMVLDASEKRCIRP---- 1184
M++C D CI D C ++ C E + P
Sbjct: 998 IRMEQCYLKWDEDECIHPVPGKFRMDACCCAVGAAWGTECEECPKPGTKEYETLCPRGAG 1057
Query: 1185 -AESNEQIEETDVYQDLCWEHLSDEYVCSRPLVGKQTTYTECCCLYGEAWGMQCALCPLK 1243
A + + Y+D+ E + +C+ +C C G A M+ C
Sbjct: 1058 FANRGDVLTGRPFYKDIN-ECKAFPGMCTYGKCRNTIGSFKCRCNSGFALDMEERNCT-- 1114
Query: 1244 DSDDYAQLCNIPVTGRRQPYGRDALVDFSEQYTPEADPYFIQDRFLNSFEELQAEECG-- 1301
D D+ C I G V+ + E + + F+ + +EC
Sbjct: 1115 DIDE----CRISP----DLCGSGICVNTPGSFECECFEGY-ESGFMMMKNCMDIDECERN 1165
Query: 1302 -ILNGCENGRCVRVQEGYTCDCFDGYHLDTAKMTCVDVNECDELNNRMSLCKNAKCINTD 1360
+L C G CV + + CDC G+ L ++ CVD+NEC +N LC+N KC+N
Sbjct: 1166 PLL--CRGGTCVNTEGSFQCDCPLGHELSPSREDCVDINECSLSDN---LCRNGKCVNMI 1220
Query: 1361 GSYKCLCLPGYVPSDKPNYCTPLNTALNLEKDSDLE 1396
G+Y+C C PGY + CT ++ + + D +
Sbjct: 1221 GTYQCSCNPGYQATPDRQGCTDIDECMIMNGGCDTQ 1256
Score = 352 bits (903), Expect = 1e-96
Identities = 248/827 (29%), Positives = 360/827 (43%), Gaps = 140/827 (16%)
Query: 548 EINECTVNPDICGAGHCINLPVRYTCICYEGYRFSEQQRKCVDIDECTQVQHLCSQGRCE 607
+++EC P IC G+CIN + C C G++ SE +KC DIDEC+ + +C G C
Sbjct: 276 DVDECQAIPGICQGGNCINTVGSFECRCPAGHKQSETTQKCEDIDECSIIPGICETGECS 335
Query: 608 NTEGSFLCICPAGFMASEEGTNCIDVDECLRPDVCGEGHCVNTVGAFRCEYCDSGYRMTQ 667
NT GS+ C+CP G++ S +G+ CID G C + + RC G RMT+
Sbjct: 336 NTVGSYFCVCPRGYVTSTDGSRCIDQ---------RTGMCFSGLVNGRCAQELPG-RMTK 385
Query: 668 RGRCEDIDECLNPSTCPDEQCVNSPGSYQ--C--------VPCTEGFR----GWNGQCLD 713
C + C T P+ V Y+ C +P + G R G NG
Sbjct: 386 MQCCCEPGRCWGIGTIPEACPVRGSEEYRRLCMDGLPMGGIPGSAGSRPGGTGGNGFAPS 445
Query: 714 VD--------ECLEPNVCANGDCSNLEGSYMCSCHKGYTRTPDHKHCRDIDECQ-QGNLC 764
+ P NG + G+ + + +G T + ID C+ NLC
Sbjct: 446 GNGNGYGPGGTGFIPIPGGNGFSPGVGGAGVGAGGQGPIITGLTILNQTIDICKHHANLC 505
Query: 765 VNGQCKNTEGSFRCTCGQGYQLSAAKDQCEDIDECQHRHLCAHGQCRNTEGSFQCVCDQG 824
+NG+C T S+RC C GY+ A D C D+DEC + C +G C NT GS+ C C G
Sbjct: 506 LNGRCIPTVSSYRCECNMGYKQDANGD-CIDVDECT-SNPCTNGDCVNTPGSYYCKCHAG 563
Query: 825 YRASGLGDHCEDINECLEDKSVCQRGDCINTAGSYDCTCPDGFQL-DDNKTCQDINECEH 883
++ + C DI+EC+++ +C+ G C+NT GS+ C C GF+L D K C D +EC
Sbjct: 564 FQRTPTKQACIDIDECIQNGVLCKNGRCVNTDGSFQCICNAGFELTTDGKNCVDHDECTT 623
Query: 884 PGLCGPQGECLNTEGSFHCVCQQGFSISADGRTCEDIDECVNNTVCDSHGFCDNTAGSFR 943
+C G C+N +GSF C+C+ GF ++ +GR C D+DEC +C +G C N+ GSFR
Sbjct: 624 TNMC-LNGMCINEDGSFKCICKPGFVLAPNGRYCTDVDECQTPGIC-MNGHCINSEGSFR 681
Query: 944 CLCYQGFQAPQDGQGCVDV---NEC--ELLSGVCGEAFCENVEGSFLCVCADENQEYSPM 998
C C G DG+ CVD + C + GVC F V S C CA+ + +
Sbjct: 682 CDCPPGLAVGMDGRVCVDTHMRSTCYGGIKKGVCVRPFPGAVTKS-ECCCANPDYGFGEP 740
Query: 999 TGQCRSRTSTDL------DVDVDQPKEEKKECYYNLNDASLCDNVLAPNVTKQECCCTSG 1052
C ++ S + V + + EC D +C N + N+ C
Sbjct: 741 CQPCPAKNSAEFHGLCSSGVGITVDGRDINECAL---DPDICANGICENLRGSYRC---- 793
Query: 1053 AGWGDNCEIFPCPVLGTAEFTEMCPKGKGFVPAGESSSEAGGENYKDADECLLFGQEICK 1112
NC G+ P +A G N D DECL+ + +C
Sbjct: 794 -----NC-------------------NSGYEP------DASGRNCIDIDECLV-NRLLCD 822
Query: 1113 NGFCLNTRPGYECYCKQGTYYDPVKLQCFDMDECQDPSSCIDGQCVNTEGSYNCFCTHPM 1172
NG C NT Y C C G + C D++EC+ + C++G C N GS+NC C+
Sbjct: 823 NGLCRNTPGSYSCTCPPGYVFRTETETCEDINECES-NPCVNGACRNNLGSFNCECSPGS 881
Query: 1173 VLDASEKRCIRPAESNEQIEETDVYQDLCWEHLSDEYVCSRPLVGKQTTYTECCCLYGEA 1232
L ++ CI D + CW ++ D C + G T +ECC G A
Sbjct: 882 KLSSTGLICI------------DSLKGTCWLNIQDSR-CEVNING-ATLKSECCATLGAA 927
Query: 1233 WGMQCALCPLKDSDDYAQLCNIPVTGRRQPYGRDALVDFSEQYTPEADPYFIQDRFLNSF 1292
WG C C L + C P G + + +
Sbjct: 928 WGSPCERCELDTA------C---------PRGLARIKGVTCE------------------ 954
Query: 1293 EELQAEECGILNG-CENGRCVRVQEGYTCDCFDGYHLDTAKMTCVDV 1338
EC + G C NGRCV + + C+C +G LD C+D+
Sbjct: 955 ---DVNECEVFPGVCPNGRCVNSKGSFHCECPEGLTLDGTGRVCLDI 998
Score = 320 bits (821), Expect = 5e-87
Identities = 190/521 (36%), Positives = 244/521 (46%), Gaps = 52/521 (9%)
Query: 548 EINECTVNPDICGAGHCINLPVRYTCICYEGYRFSEQQRKCVDIDECTQVQHLC-SQGR- 605
+INEC NP +C A C+N Y C C GY E Q+ C D+DEC + H C S+G
Sbjct: 2253 DINECAQNPLLC-AFRCMNTFGSYECTCPIGYALREDQKMCKDLDECAEGLHDCESRGMM 2311
Query: 606 CENTEGSFLCICPAGFMASEEGTNCIDVDEC-LRPDVCGEGHCVNTVGAFRCEYCDSGYR 664
C+N G+F+CICP G +G C+D +EC +P +C G CVN +G++RCE C+ G++
Sbjct: 2312 CKNLIGTFMCICPPGMARRPDGEGCVDENECRTKPGICENGRCVNIIGSYRCE-CNEGFQ 2370
Query: 665 MTQRG-RCEDIDECLNPSTCPDEQCVNSPGSYQCVP----CTEGFRGWNGQC-------- 711
+ G C D + L + C + S V C +G RGW QC
Sbjct: 2371 SSSSGTECLDNRQGLCFAEVLQTICQMASSSRNLVTKSECCCDGGRGWGHQCELCPLPGT 2430
Query: 712 -----------------LDVDEC-LEPNVCANGDCSNLEGSYMCSCHKGYTRTPDHKHCR 753
D+DEC + PN+C NG C N GS+ C C GYT C
Sbjct: 2431 AQYKKICPHGPGYTTDGRDIDECKVMPNLCTNGQCINTMGSFRCFCKVGYTTDISGTSCI 2490
Query: 754 DIDECQQGNLCVNGQCKNTEGSFRCTCGQGYQLSAAKDQCEDIDECQHRHLCAHGQCRNT 813
D+DEC Q N CKNTEGS++C+C +GY L C+D+DECQ + C NT
Sbjct: 2491 DLDECSQSPKPCNYICKNTEGSYQCSCPRGYVLQEDGKTCKDLDECQTKQHNCQFLCVNT 2550
Query: 814 EGSFQCVCDQGYRASGLGDHCEDINECLEDKSVC-QRGDCINTAGSYDCTCPDGFQLD-D 871
G F C C G+ C D NEC S+C +G C NT GS+ C C GF LD
Sbjct: 2551 LGGFTCKCPPGFTQHHTA--CIDNNECGSQPSLCGAKGICQNTPGSFSCECQRGFSLDAT 2608
Query: 872 NKTCQDINECEHPGLCGPQGECLNTEGSFHCVCQQGFSISADGRTCEDIDECVNNTVCDS 931
C+D++EC+ C Q C N G + C C QG+ C D +EC N C S
Sbjct: 2609 GLNCEDVDECDGNHRC--QHGCQNILGGYRCGCPQGYIQHYQWNQCVDENECSNPNACGS 2666
Query: 932 HGFCDNTAGSFRCLCYQGFQAPQDGQGCVDVNECELLSGVCGEAFCENVEGSFLCVCADE 991
C NT GS++C C GF Q C DVNEC C C N EG +LC C
Sbjct: 2667 -ASCYNTLGSYKCACPSGFSFDQFSSACHDVNECSSSKNPCNYG-CSNTEGGYLCGCPP- 2723
Query: 992 NQEYSPMTGQCRSRTS------TDLDVDVDQPKEEKKECYY 1026
Y G C S LD +VD+ E Y
Sbjct: 2724 -GYYRVGQGHCVSGMGFNKGQYLSLDTEVDEENALSPEACY 2763
Score = 211 bits (538), Expect = 3e-54
Identities = 122/349 (34%), Positives = 174/349 (49%), Gaps = 22/349 (6%)
Query: 544 TQVTEINECTVNPDICGAGHCINLPVRYTCICYEGYRFSEQQRKCVDIDECTQVQHLCSQ 603
T +I+EC V P++C G CIN + C C GY C+D+DEC+Q C+
Sbjct: 2445 TDGRDIDECKVMPNLCTNGQCINTMGSFRCFCKVGYTTDISGTSCIDLDECSQSPKPCNY 2504
Query: 604 GRCENTEGSFLCICPAGFMASEEGTNCIDVDECLRPDVCGEGHCVNTVGAFRCEYCDSGY 663
C+NTEGS+ C CP G++ E+G C D+DEC + CVNT+G F C+ C G+
Sbjct: 2505 -ICKNTEGSYQCSCPRGYVLQEDGKTCKDLDECQTKQHNCQFLCVNTLGGFTCK-CPPGF 2562
Query: 664 RMTQRGRCEDIDEC-LNPSTCPDEQ-CVNSPGSYQCVPCTEGF----RGWNGQCLDVDEC 717
C D +EC PS C + C N+PGS+ C C GF G N C DVDEC
Sbjct: 2563 TQ-HHTACIDNNECGSQPSLCGAKGICQNTPGSFSC-ECQRGFSLDATGLN--CEDVDEC 2618
Query: 718 LEPNVCANGDCSNLEGSYMCSCHKGYTRTPDHKHCRDIDECQQGNLCVNGQCKNTEGSFR 777
+ C +G C N+ G Y C C +GY + C D +EC N C + C NT GS++
Sbjct: 2619 DGNHRCQHG-CQNILGGYRCGCPQGYIQHYQWNQCVDENECSNPNACGSASCYNTLGSYK 2677
Query: 778 CTCGQGYQLSAAKDQCEDIDEC-QHRHLCAHGQCRNTEGSFQCVCDQGYRASGLGDHCE- 835
C C G+ C D++EC ++ C +G C NTEG + C C GY G G HC
Sbjct: 2678 CACPSGFSFDQFSSACHDVNECSSSKNPCNYG-CSNTEGGYLCGCPPGYYRVGQG-HCVS 2735
Query: 836 ----DINECLEDKSVCQRGDCINTAGSYDCTCPDGFQLDDNKTCQDINE 880
+ + L + + ++ Y+C +G+ D++ + I+E
Sbjct: 2736 GMGFNKGQYLSLDTEVDEENALSPEACYECKI-NGYSKKDSRQKRSIHE 2783
Score = 209 bits (533), Expect = 1e-53
Identities = 217/841 (25%), Positives = 301/841 (35%), Gaps = 202/841 (24%)
Query: 636 CLRPDVC--GEGHCVNTVGAFRCEYCDSGYRMTQRGRCEDIDECLNPSTCPDEQCVNSPG 693
C RP++C G +T G+ + C C+N TC D+ C G
Sbjct: 124 CSRPNMCTCSSGQISSTCGSKSIQQCSV--------------RCMNGGTCADDHCQCQKG 169
Query: 694 ---SYQCVPCTEGFRGWNGQCLDVDECLEPNVCANGDCSNLEGSYMCSCHKGYTRTPDHK 750
+Y P E NG C + C+ PN CA C + G C + Y P
Sbjct: 170 YIGTYCGQPVCE-----NG-CQNGGRCIGPNRCA---C--VYGFTGPQCERDYRTGPCFT 218
Query: 751 HCRDIDECQ---QGNLCVNGQCKNTEG---SFRCT--------CGQGYQLSAAKDQCEDI 796
+ CQ G +C C T G C C +G+ + C+D+
Sbjct: 219 QVNN-QMCQGQLTGIVCTKTLCCATIGRAWGHPCEMCPAQPQPCRRGFIPNIRTGACQDV 277
Query: 797 DECQH-RHLCAHGQCRNTEGSFQCVCDQGYRASGLGDHCEDINECLEDKSVCQRGDCINT 855
DECQ +C G C NT GSF+C C G++ S CEDI+EC +C+ G+C NT
Sbjct: 278 DECQAIPGICQGGNCINTVGSFECRCPAGHKQSETTQKCEDIDECSIIPGICETGECSNT 337
Query: 856 AGSYDCTCPDGFQLD-DNKTCQDINECEHPGLCGP---QGECL----NTEGSFHCVCQQG 907
GSY C CP G+ D C D + G+C G C C C+ G
Sbjct: 338 VGSYFCVCPRGYVTSTDGSRCID----QRTGMCFSGLVNGRCAQELPGRMTKMQCCCEPG 393
Query: 908 FSISADGRTCEDIDECVNNTVCDSHGFCDNTAGSFRCLCYQGFQAPQDGQGCVDVNECEL 967
C I C G + +R LC G G + +
Sbjct: 394 --------RCWGIGTIPE--ACPVRG-----SEEYRRLCMDGLP-----MGGIPGSAGSR 433
Query: 968 LSGVCGEAFCENVEGS--------FLCVCADENQEYSPMTGQCRSRTS---------TDL 1010
G G F + G+ F+ + +SP G T L
Sbjct: 434 PGGTGGNGFAPSGNGNGYGPGGTGFIPIPGGNG--FSPGVGGAGVGAGGQGPIITGLTIL 491
Query: 1011 DVDVDQPKEEKKECYYNLNDASLCDNVLAPNVTKQECCCTSGAGWG--------DNCEIF 1062
+ +D K C LN + P V+ C C G D C
Sbjct: 492 NQTIDICKHHANLC---LNGRCI------PTVSSYRCECNMGYKQDANGDCIDVDECTSN 542
Query: 1063 PCP----VLGTAEFTEMCPKGKGFVPAGESSSEAGGENYKDADECLLFGQEICKNGFCLN 1118
PC V + C G P ++ D DEC+ G +CKNG C+N
Sbjct: 543 PCTNGDCVNTPGSYYCKCHAGFQRTPTKQACI--------DIDECIQNG-VLCKNGRCVN 593
Query: 1119 TRPGYECYCKQGTYYDPVKLQCFDMDECQDPSSCIDGQCVNTEGSYNCFCTHPMVLDASE 1178
T ++C C G C D DEC + C++G C+N +GS+ C C VL +
Sbjct: 594 TDGSFQCICNAGFELTTDGKNCVDHDECTTTNMCLNGMCINEDGSFKCICKPGFVLAPNG 653
Query: 1179 KRCIRPAE--------SNEQIEETDVYQDLCWEHLS---------------------DEY 1209
+ C E + I ++ C L+ +
Sbjct: 654 RYCTDVDECQTPGICMNGHCINSEGSFRCDCPPGLAVGMDGRVCVDTHMRSTCYGGIKKG 713
Query: 1210 VCSRPLVGKQTTYTECCCLYGE-AWGMQCALCPLKDSDDYAQLCN----IPVTGRRQPYG 1264
VC RP G T +ECCC + +G C CP K+S ++ LC+ I V GR
Sbjct: 714 VCVRPFPG-AVTKSECCCANPDYGFGEPCQPCPAKNSAEFHGLCSSGVGITVDGR----- 767
Query: 1265 RDALVDFSEQYTPEADPYFIQDRFLNSFEELQAEECGI-LNGCENGRCVRVQEGYTCDCF 1323
EC + + C NG C ++ Y C+C
Sbjct: 768 -------------------------------DINECALDPDICANGICENLRGSYRCNCN 796
Query: 1324 DGYHLDTAKMTCVDVNECDELNNRMSLCKNAKCINTDGSYKCLCLPGYVPSDKPNYCTPL 1383
GY D + C+D++EC L NR+ LC N C NT GSY C C PGYV + C +
Sbjct: 797 SGYEPDASGRNCIDIDEC--LVNRL-LCDNGLCRNTPGSYSCTCPPGYVFRTETETCEDI 853
Query: 1384 N 1384
N
Sbjct: 854 N 854
Score = 159 bits (402), Expect = 2e-38
Identities = 178/745 (23%), Positives = 257/745 (34%), Gaps = 167/745 (22%)
Query: 657 EYCDSGYRMTQRGRCEDIDECLN-PSTCPDEQCVNSPGSYQCVPCTEGFRGWNGQCLDVD 715
EY + G + R R + L P+ C GS C G++ G +
Sbjct: 62 EYREEGAAVASRVRRRGQQDVLRGPNVC---------GSRFHSYCCPGWKTLPGG----N 108
Query: 716 ECLEP---NVCANGDCSNLEGSYMCSCHKGY-TRTPDHKHCRDID-ECQQGNLCVNGQCK 770
+C+ P N C +G CS MC+C G + T K + C G C + C+
Sbjct: 109 QCIVPICRNSCGDGFCSRPN---MCTCSSGQISSTCGSKSIQQCSVRCMNGGTCADDHCQ 165
Query: 771 NTEGSFRCTCGQGYQLSAAKDQCEDIDECQHRHLCAHGQCRNTEGSFQCVCDQGYRASGL 830
+G CGQ CE+ CQ+ C G +C C G+
Sbjct: 166 CQKGYIGTYCGQPV--------CEN--GCQNGGRCI--------GPNRCACVYGFT---- 203
Query: 831 GDHCEDINECLEDKSVCQRGDCINTAGSYDCTCP-DGFQLDDNKTCQDINEC-EHP-GLC 887
G CE + G C + C G C I HP +C
Sbjct: 204 GPQCE---------RDYRTGPCFTQVNNQMCQGQLTGIVCTKTLCCATIGRAWGHPCEMC 254
Query: 888 GPQGECLNTEGSFHCVCQQGFSISADGRTCEDIDECVNNTVCDSHGFCDNTAGSFRCLCY 947
Q + C++GF + C+D+DEC G C NT GSF C C
Sbjct: 255 PAQPQ----------PCRRGFIPNIRTGACQDVDECQAIPGICQGGNCINTVGSFECRCP 304
Query: 948 QGFQAPQDGQGCVDVNECELLSGVCGEAFCENVEGSFLCVCADENQEYSPMTGQCRSRTS 1007
G + + Q C D++EC ++ G+C C N GS+ CVC + Y TS
Sbjct: 305 AGHKQSETTQKCEDIDECSIIPGICETGECSNTVGSYFCVCP---RGYV---------TS 352
Query: 1008 TDLDVDVDQPKEEKKECYYNLNDASLCDNVLAPNVTKQECCCTSGAGWGDNCEIFPCPVL 1067
TD +DQ C+ L + C L +TK +CCC G WG CPV
Sbjct: 353 TDGSRCIDQ---RTGMCFSGLVNGR-CAQELPGRMTKMQCCCEPGRCWGIGTIPEACPVR 408
Query: 1068 GTAEFTEMC-----------------------------------PKGKGFVP-------- 1084
G+ E+ +C P G GF+P
Sbjct: 409 GSEEYRRLCMDGLPMGGIPGSAGSRPGGTGGNGFAPSGNGNGYGPGGTGFIPIPGGNGFS 468
Query: 1085 --AGESSSEAGGEN--------YKDADECLLFGQEICKNGFCLNTRPGYECYCKQGTYYD 1134
G + AGG+ + +C NG C+ T Y C C G Y
Sbjct: 469 PGVGGAGVGAGGQGPIITGLTILNQTIDICKHHANLCLNGRCIPTVSSYRCECNMG-YKQ 527
Query: 1135 PVKLQCFDMDECQDPSSCIDGQCVNTEGSYNCFCTHPMVLDASEKRCIRPAESNEQIEET 1194
C D+DEC + C +G CVNT GSY C C +++ CI + +E I+
Sbjct: 528 DANGDCIDVDECTS-NPCTNGDCVNTPGSYYCKCHAGFQRTPTKQACI---DIDECIQNG 583
Query: 1195 DVYQDLCWEHLSDEYVCSRPLVGKQTTYTECCCLYGEAWGMQCALCPLKDSDDYAQLCNI 1254
+ ++ + + C + TT + C + E L + ++D + C
Sbjct: 584 VLCKNGRCVNTDGSFQCICNAGFELTTDGKNCVDHDECTTTNMCLNGMCINEDGSFKCIC 643
Query: 1255 PVTGRRQPYGRDALVDFSEQYTPEADPYFIQDRFLNSFEELQAEECGILNGCENGRCVRV 1314
P GR Y + D EC C NG C+
Sbjct: 644 KPGFVLAPNGR---------YCTDVD------------------ECQTPGICMNGHCINS 676
Query: 1315 QEGYTCDCFDGYHLDTAKMTCVDVN 1339
+ + CDC G + CVD +
Sbjct: 677 EGSFRCDCPPGLAVGMDGRVCVDTH 701
Score = 152 bits (383), Expect = 3e-36
Identities = 145/561 (25%), Positives = 207/561 (36%), Gaps = 123/561 (21%)
Query: 884 PGLCGPQGECLNTEGSFHCVCQQGFSISADGRTCEDIDECVNNT---VCDSHGFCDNTAG 940
P +CG + FH C G+ G C + C N+ C C ++G
Sbjct: 86 PNVCGSR---------FHSYCCPGWKTLPGGNQCI-VPICRNSCGDGFCSRPNMCTCSSG 135
Query: 941 SFRCLCYQGFQAPQ-------DGQGCVDVNECELLSGV----CGEAFCEN-VEGSFLCVC 988
C G ++ Q +G C D + C+ G CG+ CEN + C+
Sbjct: 136 QISSTC--GSKSIQQCSVRCMNGGTCAD-DHCQCQKGYIGTYCGQPVCENGCQNGGRCIG 192
Query: 989 ADENQEYSPMTG-QCRSRTSTDLDVDVDQPKEEKKECYYNLNDASLCDNVLAPNV-TKQE 1046
+ TG QC T C+ +N+ +C L V TK
Sbjct: 193 PNRCACVYGFTGPQCERDYRTG-------------PCFTQVNN-QMCQGQLTGIVCTKTL 238
Query: 1047 CCCTSGAGWGDNCEIFPCPVLGTAEFTEMCPKGKGFVPAGESSSEAGGENYKDADECLLF 1106
CC T G WG CE+ P + P +GF+P + + +D DEC
Sbjct: 239 CCATIGRAWGHPCEMCPA---------QPQPCRRGFIPNIRTGA------CQDVDECQAI 283
Query: 1107 GQEICKNGFCLNTRPGYECYCKQGTYYDPVKLQCFDMDECQ-DPSSCIDGQCVNTEGSYN 1165
IC+ G C+NT +EC C G +C D+DEC P C G+C NT GSY
Sbjct: 284 -PGICQGGNCINTVGSFECRCPAGHKQSETTQKCEDIDECSIIPGICETGECSNTVGSYF 342
Query: 1166 CFCTHPMVLDASEKRCIRPAESNEQIEETDVYQDLCWEHLSDEYVCSRPLVGKQTTYTEC 1225
C C V RCI D +C+ L + C++ L G+ T +C
Sbjct: 343 CVCPRGYVTSTDGSRCI------------DQRTGMCFSGLVNGR-CAQELPGRMTK-MQC 388
Query: 1226 CCLYGEAWGMQC--ALCPLKDSDDYAQLC-------NIPVTGRRQPYGRD----ALVDFS 1272
CC G WG+ CP++ S++Y +LC IP + +P G A
Sbjct: 389 CCEPGRCWGIGTIPEACPVRGSEEYRRLCMDGLPMGGIPGSAGSRPGGTGGNGFAPSGNG 448
Query: 1273 EQYTPEA--------------------------DPYFIQDRFLNSFEELQAEECGILNGC 1306
Y P P LN ++ + C
Sbjct: 449 NGYGPGGTGFIPIPGGNGFSPGVGGAGVGAGGQGPIITGLTILNQTIDICKHHANL---C 505
Query: 1307 ENGRCVRVQEGYTCDCFDGYHLDTAKMTCVDVNECDELNNRMSLCKNAKCINTDGSYKCL 1366
NGRC+ Y C+C GY D A C+DV+EC + C N C+NT GSY C
Sbjct: 506 LNGRCIPTVSSYRCECNMGYKQD-ANGDCIDVDECTS-----NPCTNGDCVNTPGSYYCK 559
Query: 1367 CLPGYVPSDKPNYCTPLNTAL 1387
C G+ + C ++ +
Sbjct: 560 CHAGFQRTPTKQACIDIDECI 580
Score = 132 bits (333), Expect = 2e-30
Identities = 69/202 (34%), Positives = 103/202 (50%), Gaps = 19/202 (9%)
Query: 231 GRCFQETIGSQCGKALPGLSKQEDCCGTVGTSWGFNKCQKCPKKPSYHGYNQMMECLPGY 290
G C+ S+C + G + + +CC T+G +WG + C++C + C G
Sbjct: 896 GTCWLNIQDSRCEVNINGATLKSECCATLGAAWG-SPCERCELDTA---------CPRGL 945
Query: 291 KRVNNTFCQDINECQL-QGVCPNGECLNTMGSYRCTCKIGFGPDPTFSSCVPDPPVISEE 349
R+ C+D+NEC++ GVCPNG C+N+ GS+ C C G D T C+ I E
Sbjct: 946 ARIKGVTCEDVNECEVFPGVCPNGRCVNSKGSFHCECPEGLTLDGTGRVCLD----IRME 1001
Query: 350 KGPCYRLVSSGRQCMHPLSVHLTKQLCCCSVGKAWGPHCEKCPLPGTAAFKEICPGGMGY 409
+ CY L +C+HP+ CCC+VG AWG CE+CP PGT ++ +CP G G+
Sbjct: 1002 Q--CY-LKWDEDECIHPVPGKFRMDACCCAVGAAWGTECEECPKPGTKEYETLCPRGAGF 1058
Query: 410 TVSG-VHRRRPIHHHVGKGPVF 430
G V RP + + + F
Sbjct: 1059 ANRGDVLTGRPFYKDINECKAF 1080
Score = 108 bits (269), Expect = 5e-23
Identities = 57/134 (42%), Positives = 73/134 (54%), Gaps = 9/134 (6%)
Query: 283 MMECLPGY-KRVNNTFCQDINECQLQ-GVCPNGECLNTMGSYRCTCKIGFGPDPTFSSCV 340
M C PG +R + C D NEC+ + G+C NG C+N +GSYRC C GF + + C
Sbjct: 2320 MCICPPGMARRPDGEGCVDENECRTKPGICENGRCVNIIGSYRCECNEGFQSSSSGTEC- 2378
Query: 341 PDPPVISEEKGPCYRLVSSGRQCMHPLSVHL-TKQLCCCSVGKAWGPHCEKCPLPGTAAF 399
+ +G C+ V M S +L TK CCC G+ WG CE CPLPGTA +
Sbjct: 2379 -----LDNRQGLCFAEVLQTICQMASSSRNLVTKSECCCDGGRGWGHQCELCPLPGTAQY 2433
Query: 400 KEICPGGMGYTVSG 413
K+ICP G GYT G
Sbjct: 2434 KKICPHGPGYTTDG 2447
Score = 101 bits (252), Expect = 4e-21
Identities = 67/202 (33%), Positives = 93/202 (46%), Gaps = 49/202 (24%)
Query: 252 QEDCCGTVGTSWGFNKCQKCPKKPSYHGYNQMMECLPGYK--RVN--NTFCQDINECQ-L 306
+ CC ++G +WG N C+ CP S Y PG + R N +DI+ECQ L
Sbjct: 1603 RSSCCCSLGKAWG-NPCETCPPVNSTEYYT----LCPGGEGFRPNPITIILEDIDECQEL 1657
Query: 307 QGVCPNGECLNTMGSYRCTCKIGF----------------------GPDPTFS-----SC 339
G+C G C+NT GS++C C G+ GP ++ +C
Sbjct: 1658 PGLCQGGNCINTFGSFQCECPQGYYLSEDTRICEDIDECFAHPGVCGPGTCYNTLGNYTC 1717
Query: 340 VPDPPVISEEKGP---------CYRLVSSGRQCMHPLSVHLTKQLCCC--SVGKAWGPHC 388
+ P + G CYR +G C + L ++TK++CCC +VGKAW C
Sbjct: 1718 ICPPEYMQVNGGHNCMDMRKSFCYRSY-NGTTCENELPFNVTKRMCCCTYNVGKAWNKPC 1776
Query: 389 EKCPLPGTAAFKEICPGGMGYT 410
E CP PGTA FK IC G+T
Sbjct: 1777 EPCPTPGTADFKTICGNIPGFT 1798
Score = 96.3 bits (238), Expect = 2e-19
Identities = 58/218 (26%), Positives = 87/218 (39%), Gaps = 51/218 (23%)
Query: 231 GRCFQETIGSQCGKALPGLSKQED-CCGTVGTSWGFNKCQKCPKKPSYHGYNQMMECLPG 289
G CF + C L G+ + CC T+G +WG + C+ CP +P C G
Sbjct: 214 GPCFTQVNNQMCQGQLTGIVCTKTLCCATIGRAWG-HPCEMCPAQPQ--------PCRRG 264
Query: 290 Y-KRVNNTFCQDINECQ-LQGVCPNGECLNTMGSYRCTCKIGFGPDPTFSSC-------- 339
+ + CQD++ECQ + G+C G C+NT+GS+ C C G T C
Sbjct: 265 FIPNIRTGACQDVDECQAIPGICQGGNCINTVGSFECRCPAGHKQSETTQKCEDIDECSI 324
Query: 340 ----------------------------VPDPPVISEEKGPCYRLVSSGRQCMHPLSVHL 371
I + G C+ + +GR C L +
Sbjct: 325 IPGICETGECSNTVGSYFCVCPRGYVTSTDGSRCIDQRTGMCFSGLVNGR-CAQELPGRM 383
Query: 372 TKQLCCCSVGKAWGPHC--EKCPLPGTAAFKEICPGGM 407
TK CCC G+ WG E CP+ G+ ++ +C G+
Sbjct: 384 TKMQCCCEPGRCWGIGTIPEACPVRGSEEYRRLCMDGL 421
Score = 90.1 bits (222), Expect = 1e-17
Identities = 45/130 (34%), Positives = 64/130 (49%), Gaps = 8/130 (6%)
Query: 286 CLPGYKRV-NNTFCQDINECQLQGVCPNGECLNTMGSYRCTCKIGFGPDPTFSSCVPDPP 344
C PG+ N +C D++ECQ G+C NG C+N+ GS+RC C G CV
Sbjct: 643 CKPGFVLAPNGRYCTDVDECQTPGICMNGHCINSEGSFRCDCPPGLAVGMDGRVCVD--- 699
Query: 345 VISEEKGPCYRLVSSGRQCMHPLSVHLTKQLCCC-SVGKAWGPHCEKCPLPGTAAFKEIC 403
+ + CY + G C+ P +TK CCC + +G C+ CP +A F +C
Sbjct: 700 --THMRSTCYGGIKKG-VCVRPFPGAVTKSECCCANPDYGFGEPCQPCPAKNSAEFHGLC 756
Query: 404 PGGMGYTVSG 413
G+G TV G
Sbjct: 757 SSGVGITVDG 766
Score = 86.7 bits (213), Expect = 1e-16
Identities = 67/200 (33%), Positives = 88/200 (44%), Gaps = 30/200 (15%)
Query: 231 GRCFQETIGS---QCGKALPGLSKQEDCCGTVGTSWGFNKCQKCPKKPSYHGYNQMME-- 285
GRCF E IGS C + ++C T N+C P S G Q +E
Sbjct: 1988 GRCFNE-IGSFKCLCNEGYELTPDGKNCIDT-------NECVALPGSCS-PGTCQNLEGS 2038
Query: 286 ----CLPGYKRVNNTFCQDINECQLQ-GVCPNGECLNTMGSYRCTCKIGFGPDPTFSSCV 340
C PGY+ V + C DINEC +C G C NT G ++C C GF C
Sbjct: 2039 FRCICPPGYE-VKSENCIDINECDEDPNICLFGSCTNTPGGFQCLCPPGFVLSDNGRRC- 2096
Query: 341 PDPPVISEEKGPCYRLVSSGRQCMHPLSVHLTKQLCCCSV--GKAWGPHCEKCPLPGTAA 398
+ C+ +G+ C P + + TK CCCS G+ WG CE CP A
Sbjct: 2097 -----FDTRQSFCFTNFENGK-CSVPKAFNTTKAKCCCSKMPGEGWGDPCELCPKDDEVA 2150
Query: 399 FKEICPGGMGYTVSGVHRRR 418
F+++CP G G TV +H R
Sbjct: 2151 FQDLCPYGHG-TVPSLHDTR 2169
Score = 86.3 bits (212), Expect = 2e-16
Identities = 43/116 (37%), Positives = 56/116 (48%), Gaps = 10/116 (8%)
Query: 298 CQDINECQLQGVCPNGECLNTMGSYRCTCKIGFGPDPTFSSCVPDPPVISEEKGPCYRLV 357
C DI+EC C NG C+NT G Y C C F +PT CV + G CY
Sbjct: 1530 CTDIDECADPINCVNGLCVNTPGRYECNCPPDFQLNPTGVGCVDN------RVGNCYLKF 1583
Query: 358 S----SGRQCMHPLSVHLTKQLCCCSVGKAWGPHCEKCPLPGTAAFKEICPGGMGY 409
C + V +++ CCCS+GKAWG CE CP + + +CPGG G+
Sbjct: 1584 GPRGDGSLSCNTEIGVGVSRSSCCCSLGKAWGNPCETCPPVNSTEYYTLCPGGEGF 1639
Score = 80.1 bits (196), Expect = 1e-14
Identities = 46/126 (36%), Positives = 69/126 (54%), Gaps = 10/126 (7%)
Query: 231 GRCFQETIGSQCGKALPG--LSKQEDCCGTVGTSWGFNKCQKCPKKPSYHGYNQMMECLP 288
G CF E + + C A L + +CC G WG ++C+ CP P Y ++ P
Sbjct: 2384 GLCFAEVLQTICQMASSSRNLVTKSECCCDGGRGWG-HQCELCPL-PGTAQYKKICPHGP 2441
Query: 289 GYKRVNNTFCQDINECQLQ-GVCPNGECLNTMGSYRCTCKIGFGPDPTFSSCVPDPPVIS 347
GY T +DI+EC++ +C NG+C+NTMGS+RC CK+G+ D + +SC+ D S
Sbjct: 2442 GY----TTDGRDIDECKVMPNLCTNGQCINTMGSFRCFCKVGYTTDISGTSCI-DLDECS 2496
Query: 348 EEKGPC 353
+ PC
Sbjct: 2497 QSPKPC 2502
Score = 75.5 bits (184), Expect = 3e-13
Identities = 49/174 (28%), Positives = 78/174 (44%), Gaps = 13/174 (7%)
Query: 174 VSRIDGPTGQKTKEAQ--PGQSQVSYQGLPVQKTQTIHSTYSHQQVIPHVYPVAAKTQLG 231
++RI G T + E + PG V G V + H + V ++
Sbjct: 945 LARIKGVTCEDVNECEVFPG---VCPNGRCVNSKGSFHCECPEGLTLDGTGRVCLDIRME 1001
Query: 232 RCFQETIGSQCGKALPGLSKQEDCCGTVGTSWGFNKCQKCPKKPSYHGYNQMMECLPGYK 291
+C+ + +C +PG + + CC VG +WG +C++CPK P Y + G+
Sbjct: 1002 QCYLKWDEDECIHPVPGKFRMDACCCAVGAAWG-TECEECPK-PGTKEYETLCPRGAGFA 1059
Query: 292 R-----VNNTFCQDINECQ-LQGVCPNGECLNTMGSYRCTCKIGFGPDPTFSSC 339
F +DINEC+ G+C G+C NT+GS++C C GF D +C
Sbjct: 1060 NRGDVLTGRPFYKDINECKAFPGMCTYGKCRNTIGSFKCRCNSGFALDMEERNC 1113
Score = 64.3 bits (155), Expect = 8e-10
Identities = 62/239 (25%), Positives = 83/239 (34%), Gaps = 81/239 (33%)
Query: 242 CGKALPGLSKQEDCCGTVGTSWGFNK-CQKCPKKPS--YHGY------------------ 280
C + PG + +CC +GF + CQ CP K S +HG
Sbjct: 715 CVRPFPGAVTKSECC-CANPDYGFGEPCQPCPAKNSAEFHGLCSSGVGITVDGRDINECA 773
Query: 281 -------NQMMECLPGYKRVN----------NTFCQDINECQLQGV-CPNGECLNTMGSY 322
N + E L G R N C DI+EC + + C NG C NT GSY
Sbjct: 774 LDPDICANGICENLRGSYRCNCNSGYEPDASGRNCIDIDECLVNRLLCDNGLCRNTPGSY 833
Query: 323 RCTCKIGF------GPDPTFSSCVPDPPV----------------------------ISE 348
CTC G+ + C +P V I
Sbjct: 834 SCTCPPGYVFRTETETCEDINECESNPCVNGACRNNLGSFNCECSPGSKLSSTGLICIDS 893
Query: 349 EKGPCYRLVSSGRQCMHPLSVHLTKQLCCCSVGKAWGPHCEKCPLPGTAAFKEICPGGM 407
KG C+ + R C ++ K CC ++G AWG CE+C L CP G+
Sbjct: 894 LKGTCWLNIQDSR-CEVNINGATLKSECCATLGAAWGSPCERCEL------DTACPRGL 945
Score = 63.9 bits (154), Expect = 1e-09
Identities = 34/110 (30%), Positives = 54/110 (49%), Gaps = 4/110 (3%)
Query: 233 CFQETIGSQCGKALPGLSKQEDCCGTVGTSWGFNK-CQKCPKKPSYHGYNQMMECLPGYK 291
C++ G+ C LP + CC T +NK C+ CP P + + +PG+
Sbjct: 1740 CYRSYNGTTCENELPFNVTKRMCCCTYNVGKAWNKPCEPCPT-PGTADFKTICGNIPGFT 1798
Query: 292 -RVNNTFCQDINEC-QLQGVCPNGECLNTMGSYRCTCKIGFGPDPTFSSC 339
++ DI+EC ++ G+C NG C+N +GS+RC C GF + C
Sbjct: 1799 FDIHTGKAVDIDECKEIPGICANGVCINQIGSFRCECPTGFSYNDLLLVC 1848
Score = 60.8 bits (146), Expect = 9e-09
Identities = 52/201 (25%), Positives = 74/201 (36%), Gaps = 54/201 (26%)
Query: 285 ECLPGYKRVNNTFCQDINECQLQGVCPNGECLNTMGSYRCTCKIGFGPDPTFSSCVPDPP 344
EC GYK+ N C D++EC C NG+C+NT GSY C C GF PT +C+
Sbjct: 520 ECNMGYKQDANGDCIDVDECT-SNPCTNGDCVNTPGSYYCKCHAGFQRTPTKQACIDIDE 578
Query: 345 VISE----EKGPC--------------YRLVSSGRQCMHPLSVHLTKQL----------- 375
I + G C + L + G+ C+ T
Sbjct: 579 CIQNGVLCKNGRCVNTDGSFQCICNAGFELTTDGKNCVDHDECTTTNMCLNGMCINEDGS 638
Query: 376 --CCCSVGKAWGPH------CEKCPLPG----------TAAFKEICPGGMGYTVSG---- 413
C C G P+ ++C PG +F+ CP G+ + G
Sbjct: 639 FKCICKPGFVLAPNGRYCTDVDECQTPGICMNGHCINSEGSFRCDCPPGLAVGMDGRVCV 698
Query: 414 -VHRRRPIHHHVGKGPVFVKP 433
H R + + KG V V+P
Sbjct: 699 DTHMRSTCYGGIKKG-VCVRP 718
Score = 58.9 bits (141), Expect = 3e-08
Identities = 49/168 (29%), Positives = 69/168 (41%), Gaps = 28/168 (16%)
Query: 232 RCFQETIGSQCGKALPGLSKQEDCC-GTVGTSWGFNKCQKCPKKPSYHGY--NQMMECLP 288
+C + CG C G + ++ G Q+C + G + +C
Sbjct: 109 QCIVPICRNSCGDGFCSRPNMCTCSSGQISSTCGSKSIQQCSVRCMNGGTCADDHCQCQK 168
Query: 289 GYKRVNNTFCQDINECQLQGVCPNGECLN---TMGSYRCTCKIGFGPDPTFSSCVPDPPV 345
GY T+C Q VC NG C N +G RC C GF T C D
Sbjct: 169 GYI---GTYCG-------QPVCENG-CQNGGRCIGPNRCACVYGF----TGPQCERD--- 210
Query: 346 ISEEKGPCYRLVSSGRQCMHPLS-VHLTKQLCCCSVGKAWGPHCEKCP 392
GPC+ V++ + C L+ + TK LCC ++G+AWG CE CP
Sbjct: 211 --YRTGPCFTQVNN-QMCQGQLTGIVCTKTLCCATIGRAWGHPCEMCP 255
Score = 52.8 bits (125), Expect = 2e-06
Identities = 25/56 (44%), Positives = 28/56 (50%), Gaps = 1/56 (1%)
Query: 298 CQDINECQLQGVCPNGECLNTMGSYRCTCKIGFGPDPTFSSCVPDPPVISEEKGPC 353
C D NEC C + C NT+GSY+C C GF D FSS D S K PC
Sbjct: 2652 CVDENECSNPNACGSASCYNTLGSYKCACPSGFSFD-QFSSACHDVNECSSSKNPC 2706
Score = 51.6 bits (122), Expect = 5e-06
Identities = 32/94 (34%), Positives = 44/94 (46%), Gaps = 11/94 (11%)
Query: 264 GFNKCQK---CPKKPSYHGYNQMMECLPGYKRVNNTFCQDINEC-QLQGVCPNGECLNTM 319
G N CQ+ C P + EC G+K N C D NEC ++ VC +G C++
Sbjct: 1857 GDNLCQRNADCINSPGSY----RCECAAGFKLSPNGACVDRNECLEIPNVCSHGLCVDLQ 1912
Query: 320 GSYRCTCKIGFGPDPTFSSCVPDPPVISEEKGPC 353
GSY+C C GF + C+ V E+ PC
Sbjct: 1913 GSYQCICHNGFKASQDQTMCM---DVDECERHPC 1943
Score = 51.6 bits (122), Expect = 5e-06
Identities = 63/245 (25%), Positives = 86/245 (35%), Gaps = 69/245 (28%)
Query: 228 TQLGRCFQETIGSQCG--KALPGLSKQEDCCGTV-GTSWGFNKCQKCPKK---------- 274
T+ CF +C KA +K + CC + G WG + C+ CPK
Sbjct: 2099 TRQSFCFTNFENGKCSVPKAF-NTTKAKCCCSKMPGEGWG-DPCELCPKDDEVAFQDLCP 2156
Query: 275 ------PSYHGYNQMM------------------------ECLPGYKR-VNNTFCQDINE 303
PS H + + EC GY C D +E
Sbjct: 2157 YGHGTVPSLHDTREDVNECLESPGICSNGQCINTDGSFRCECPMGYNLDYTGVRCVDTDE 2216
Query: 304 CQLQGVCPNGECLNTMGSYRCTCKIGFGPDP-----TFSSCVPDPPVISEEKGPCYRLVS 358
C + C NG C N +GS+ C C GF P P + C +P + + C
Sbjct: 2217 CSIGNPCGNGTCTNVIGSFECNCNEGFEPGPMMNCEDINECAQNPLLCAFR---CMNTFG 2273
Query: 359 SGRQCMHPLSVHL------TKQLCCCSVG----KAWGPHCEKCPLPGTAAFKEICPGGMG 408
S +C P+ L K L C+ G ++ G C+ L GT F ICP GM
Sbjct: 2274 S-YECTCPIGYALREDQKMCKDLDECAEGLHDCESRGMMCKN--LIGT--FMCICPPGMA 2328
Query: 409 YTVSG 413
G
Sbjct: 2329 RRPDG 2333
Score = 50.1 bits (118), Expect = 2e-05
Identities = 20/43 (46%), Positives = 27/43 (62%), Gaps = 1/43 (2%)
Query: 298 CQDINECQLQ-GVCPNGECLNTMGSYRCTCKIGFGPDPTFSSC 339
C D++EC +C NG+CLN G+YRC C++GF P SC
Sbjct: 1447 CSDVDECAENINLCENGQCLNVPGAYRCECEMGFTPASDSRSC 1489
Score = 48.5 bits (114), Expect = 4e-05
Identities = 39/135 (28%), Positives = 58/135 (42%), Gaps = 27/135 (20%)
Query: 231 GRCFQETIGSQCGKALPGLSKQEDCCGTVGT-----SWGF---------NKCQKCPKKPS 276
GR F + I ++C KA PG+ C T+G+ + GF +C P
Sbjct: 1067 GRPFYKDI-NEC-KAFPGMCTYGKCRNTIGSFKCRCNSGFALDMEERNCTDIDECRISPD 1124
Query: 277 YHGYNQMM--------ECLPGYKR--VNNTFCQDINECQLQGV-CPNGECLNTMGSYRCT 325
G + EC GY+ + C DI+EC+ + C G C+NT GS++C
Sbjct: 1125 LCGSGICVNTPGSFECECFEGYESGFMMMKNCMDIDECERNPLLCRGGTCVNTEGSFQCD 1184
Query: 326 CKIGFGPDPTFSSCV 340
C +G P+ CV
Sbjct: 1185 CPLGHELSPSREDCV 1199
Score = 46.2 bits (108), Expect = 2e-04
Identities = 39/139 (28%), Positives = 59/139 (42%), Gaps = 29/139 (20%)
Query: 286 CLPGYKRVNN-TFCQDINECQLQGVCPNGECLNTMGSYRCTCKIGFGPDPTFSSCVPDPP 344
C G+K + T C D++EC+ + C NG C NT+GSY C C GF + T ++ D
Sbjct: 1919 CHNGFKASQDQTMCMDVDECE-RHPCGNGTCKNTVGSYNCLCYPGF--ELTHNNDCLD-- 1973
Query: 345 VISEEKGPCYRLVSSGRQCMHPLSVHLTKQLCCCSVGKAWGPHCEKC-------PLPGT- 396
+E + V +C + + C C+ G P + C LPG+
Sbjct: 1974 --IDECSSFFGQVCRNGRCFNEIG----SFKCLCNEGYELTPDGKNCIDTNECVALPGSC 2027
Query: 397 ---------AAFKEICPGG 406
+F+ ICP G
Sbjct: 2028 SPGTCQNLEGSFRCICPPG 2046
Score = 45.4 bits (106), Expect = 4e-04
Identities = 28/91 (30%), Positives = 40/91 (43%), Gaps = 7/91 (7%)
Query: 252 QEDCCGTVGTSWGFNKCQ--KCPKKPSYHGYNQMMECLPGYKRV-NNTFCQDINECQLQG 308
+EDC S N C+ KC + C PGY+ + C DI+EC +
Sbjct: 1195 REDCVDINECSLSDNLCRNGKCVNMIGTY----QCSCNPGYQATPDRQGCTDIDECMIMN 1250
Query: 309 VCPNGECLNTMGSYRCTCKIGFGPDPTFSSC 339
+ +C N+ GSY C+C G+ P SC
Sbjct: 1251 GGCDTQCTNSEGSYECSCSEGYALMPDGRSC 1281
Score = 45.1 bits (105), Expect = 5e-04
Identities = 36/134 (26%), Positives = 51/134 (38%), Gaps = 15/134 (11%)
Query: 285 ECLPGYKRVNNTFCQDINECQLQ-GVC-PNGECLNTMGSYRCTCKIGFGPDPTFSSCVPD 342
+C PG+ + ++T C D NEC Q +C G C NT GS+ C C+ GF D T +C
Sbjct: 2557 KCPPGFTQ-HHTACIDNNECGSQPSLCGAKGICQNTPGSFSCECQRGFSLDATGLNC--- 2612
Query: 343 PPVISEEKGPCYRLVSSGRQCMHPLSVHLTKQLCCCSVGKAWGPHCEKCPLPGTAAFKEI 402
E+ C +C H L C C G +C +
Sbjct: 2613 -----EDVDEC----DGNHRCQHGCQNILGGYRCGCPQGYIQHYQWNQCVDENECSNPNA 2663
Query: 403 CPGGMGYTVSGVHR 416
C Y G ++
Sbjct: 2664 CGSASCYNTLGSYK 2677
Score = 43.5 bits (101), Expect = 0.001
Identities = 18/43 (41%), Positives = 25/43 (58%), Gaps = 1/43 (2%)
Query: 298 CQDINECQLQG-VCPNGECLNTMGSYRCTCKIGFGPDPTFSSC 339
C D+NEC L +C GEC NT GS+ C C++G+ + C
Sbjct: 1323 CIDVNECDLNSNICMFGECENTKGSFICHCQLGYSVKKGTTGC 1365
Score = 43.1 bits (100), Expect = 0.002
Identities = 20/57 (35%), Positives = 28/57 (49%), Gaps = 2/57 (3%)
Query: 286 CLPGYKRV-NNTFCQDINECQLQ-GVCPNGECLNTMGSYRCTCKIGFGPDPTFSSCV 340
C GY + + C DI+EC+ +C G+C N G YRC C GF +C+
Sbjct: 1268 CSEGYALMPDGRSCADIDECENNPDICDGGQCTNIPGEYRCLCYDGFMASMDMKTCI 1324
Score = 42.4 bits (98), Expect = 0.003
Identities = 44/172 (25%), Positives = 65/172 (37%), Gaps = 31/172 (18%)
Query: 244 KALPGLSKQEDCCGTVGTSWGFNK-----------------CQKCPKKPSYHGYNQ---- 282
K +P L C T+G+ F K C + PK +Y N
Sbjct: 2454 KVMPNLCTNGQCINTMGSFRCFCKVGYTTDISGTSCIDLDECSQSPKPCNYICKNTEGSY 2513
Query: 283 MMECLPGYK-RVNNTFCQDINECQLQGVCPNGECLNTMGSYRCTCKIGFGPDPTFSSCVP 341
C GY + + C+D++ECQ + C+NT+G + C C GF T +C+
Sbjct: 2514 QCSCPRGYVLQEDGKTCKDLDECQTKQHNCQFLCVNTLGGFTCKCPPGFTQHHT--ACID 2571
Query: 342 D-----PPVISEEKGPCYRLVSS-GRQCMHPLSVHLTKQLCCCSVGKAWGPH 387
+ P + KG C S +C S+ T L C V + G H
Sbjct: 2572 NNECGSQPSLCGAKGICQNTPGSFSCECQRGFSLDAT-GLNCEDVDECDGNH 2622
Score = 41.2 bits (95), Expect = 0.007
Identities = 60/286 (20%), Positives = 92/286 (32%), Gaps = 56/286 (19%)
Query: 38 TCTKGSCQNSCEKGNTTTLISENGHAADTLTATNFRVVICHLPCMNGGQCSSRDKCQCPP 97
TC CQ C+KG T + +C C NGG+C ++C C
Sbjct: 158 TCADDHCQ--CQKGYIGTYCGQP---------------VCENGCQNGGRCIGPNRCACVY 200
Query: 98 NFTGKLCQIPVHGASVPKLYQHSQQPGKALGTHVIHST------------HTLPLTVTSQ 145
FTG C+ + P Q + Q + T ++ + H +
Sbjct: 201 GFTGPQCERDYR--TGPCFTQVNNQMCQGQLTGIVCTKTLCCATIGRAWGHPCEMCPAQP 258
Query: 146 QGVKVKFPPNIVNIHVKHPPEASV---------QIHQVSRID--GPTGQKTKEAQPGQSQ 194
Q + F PNI + E I+ V + P G K E
Sbjct: 259 QPCRRGFIPNIRTGACQDVDECQAIPGICQGGNCINTVGSFECRCPAGHKQSETTQKCED 318
Query: 195 VSYQGL---PVQKTQTIHSTYSHQQVIPHVYPVAAKTQLGRC--------FQETIGSQCG 243
+ + + + ++ S+ V P Y T RC F + +C
Sbjct: 319 IDECSIIPGICETGECSNTVGSYFCVCPRGY--VTSTDGSRCIDQRTGMCFSGLVNGRCA 376
Query: 244 KALPGLSKQEDCCGTVGTSWGFNKC-QKCPKKPSYHGYNQMMECLP 288
+ LPG + CC G WG + CP + S M+ LP
Sbjct: 377 QELPGRMTKMQCCCEPGRCWGIGTIPEACPVRGSEEYRRLCMDGLP 422
Score = 41.2 bits (95), Expect = 0.007
Identities = 34/123 (27%), Positives = 48/123 (39%), Gaps = 14/123 (11%)
Query: 294 NNTFCQDINECQ--LQGVCPNGECLNTMGSYRCTCKIGFGPDPTFSSCVPDPPVISEEKG 351
N C D++EC N +C+NT GSYRC C GF D S V +E
Sbjct: 1402 NGIKCIDLDECSNGTHQCSINAQCVNTPGSYRCACSEGFTGDGFTCSDV-------DECA 1454
Query: 352 PCYRLVSSGRQCMHPLSVHLTKQLCCCSVGKAWGPHCEKCPLPGTAAFKEICPGGMGYTV 411
L +G QC++ + C C +G C +F+ IC G +
Sbjct: 1455 ENINLCENG-QCLNVPGAY----RCECEMGFTPASDSRSCQDIDECSFQNICVFGTCNNL 1509
Query: 412 SGV 414
G+
Sbjct: 1510 PGM 1512
Score = 40.8 bits (94), Expect = 0.009
Identities = 23/73 (31%), Positives = 32/73 (43%), Gaps = 6/73 (8%)
Query: 39 CTKGSCQNSCEKG---NTTTLISENGHAADTLTATNFRVVICHLPCMNGGQCSSRDKCQC 95
C C+NSC G +G + T + + + C + CMNGG C+ D CQC
Sbjct: 110 CIVPICRNSCGDGFCSRPNMCTCSSGQISSTCGSKSIQQ--CSVRCMNGGTCAD-DHCQC 166
Query: 96 PPNFTGKLCQIPV 108
+ G C PV
Sbjct: 167 QKGYIGTYCGQPV 179
Score = 35.8 bits (81), Expect = 0.30
Identities = 15/36 (41%), Positives = 22/36 (61%), Gaps = 1/36 (2%)
Query: 299 QDINECQLQG-VCPNGECLNTMGSYRCTCKIGFGPD 333
Q I+ C+ +C NG C+ T+ SYRC C +G+ D
Sbjct: 493 QTIDICKHHANLCLNGRCIPTVSSYRCECNMGYKQD 528
Score = 35.8 bits (81), Expect = 0.30
Identities = 16/48 (33%), Positives = 27/48 (56%), Gaps = 3/48 (6%)
Query: 286 CLPGYK-RVNNTFCQDINECQL--QGVCPNGECLNTMGSYRCTCKIGF 330
C GY + T C D++EC++ + CLN GS++C+C+ G+
Sbjct: 1352 CQLGYSVKKGTTGCTDVDECEIGAHNCDMHASCLNIPGSFKCSCREGW 1399
Score = 34.7 bits (78), Expect = 0.66
Identities = 24/74 (32%), Positives = 33/74 (44%), Gaps = 12/74 (16%)
Query: 31 TPSICKVTC--TKGSCQNSCEKGNTTTLISENGHAADTLTATNFRVVICHLPCMN--GGQ 86
+P C C T+GS Q SC +G ++ E+G L + C C+N GG
Sbjct: 2498 SPKPCNYICKNTEGSYQCSCPRGY---VLQEDGKTCKDLDECQTKQHNCQFLCVNTLGGF 2554
Query: 87 CSSRDKCQCPPNFT 100
C+CPP FT
Sbjct: 2555 T-----CKCPPGFT 2563
Score = 33.1 bits (74), Expect = 1.9
Identities = 14/33 (42%), Positives = 16/33 (48%)
Query: 298 CQDINECQLQGVCPNGECLNTMGSYRCTCKIGF 330
C D+NEC N C NT G Y C C G+
Sbjct: 2693 CHDVNECSSSKNPCNYGCSNTEGGYLCGCPPGY 2725
>gi|51873053 fibulin 2 isoform a precursor [Homo sapiens]
Length = 1231
Score = 283 bits (725), Expect = 6e-76
Identities = 211/628 (33%), Positives = 294/628 (46%), Gaps = 85/628 (13%)
Query: 369 VHLTKQLC-CCSVG---KAWGPHCEKCPLPGTAAFKEICPGGMGYTVSGVHRRRPIHHHV 424
+ L KQ C CC +G +A G CE P +GY + V +
Sbjct: 512 ISLYKQCCDCCGLGLRVRAEGQSCESNP-------------NLGYPCNHVM----LSCCE 554
Query: 425 GKGPVFVKPKNTQPVAKSTHPPPLPAKEEPVEALTFSREHGPGVAEPEVATAPPEKEIPS 484
G+ P+ V P+ +P P P A EA RE E E+ + +P
Sbjct: 555 GEEPLIV-PEVRRP------PEPAAAPRRVSEAEMAGREALSLGTEAELPNS-----LPG 602
Query: 485 LDQEKTKLEPGQPQLSPGISTIHLH--PQFPGIVIEKTS--------PPVPVEVAPEAST 534
DQ++ L PG+ I+T+ + FPG ++ PP P A
Sbjct: 603 DDQDECLLLPGELCQHLCINTVGSYHCACFPGFSLQDDGRTCRPEGHPPQPEAPQEPALK 662
Query: 535 SSASQVIA---PTQVTEINECTVNPDICGAGHCINLPVRYTCICYEGYRFSEQQRKCVDI 591
S SQV + P + + N C N C + C C+ GY C D
Sbjct: 663 SEFSQVASNTIPLPLPQPNTCKDNGPCKQV--CSTVGGSAICSCFPGYAIMADGVSCEDQ 720
Query: 592 DECTQVQHLCSQGR-CENTEGSFLCI-----CPAGFMASEEGTNCIDVDECLRP-DVCGE 644
DEC H CS+ + C NT GSF C+ C G++ + C+D++EC+ C
Sbjct: 721 DECLMGAHDCSRRQFCVNTLGSFYCVNHTVLCADGYILNAH-RKCVDINECVTDLHTCSR 779
Query: 645 G-HCVNTVGAFRCE---YCDSGYRMTQRGRCEDIDEC-LNPSTC-PDEQCVNSPGSYQCV 698
G HCVNT+G+F C C+ GY + + G CED+DEC + TC P C N+ GS+ C
Sbjct: 780 GEHCVNTLGSFHCYKALTCEPGYAL-KDGECEDVDECAMGTHTCQPGFLCQNTKGSFYCQ 838
Query: 699 P---CTEGF-RGWNGQCLDVDECLE-PNVCANG-DCSNLEGSYMCS-----CHKGYTRTP 747
C +GF + G C+D++EC C G C N GSY C C +GY +
Sbjct: 839 ARQRCMDGFLQDPEGNCVDINECTSLSEPCRPGFSCINTVGSYTCQRNPLICARGYHASD 898
Query: 748 DHKHCRDIDECQQG-NLCVNGQ-CKNTEGSFRCTCGQGYQLSAAKDQCEDIDEC--QHRH 803
D C D++EC+ G + C GQ C N GS+RC C G+Q A C D++EC
Sbjct: 899 DGTKCVDVNECETGVHRCGEGQVCHNLPGSYRCDCKAGFQRDAFGRGCIDVNECWASPGR 958
Query: 804 LCAHGQCRNTEGSFQCVCDQGYRASGLGDHCEDINECLEDKSVCQRGDCINTAGSYDCTC 863
LC H C NT GS++C C G+ + G CED+NEC + C + +C N GSY C C
Sbjct: 959 LCQH-TCENTLGSYRCSCASGFLLAADGKRCEDVNEC--EAQRCSQ-ECANIYGSYQCYC 1014
Query: 864 PDGFQL-DDNKTCQDINECEHPGLCGPQGECLNTEGSFHCVC-QQGFSISADGRTCEDID 921
G+QL +D TC DI+EC CLN GS+ C C +QG++++A+GR+C+D+D
Sbjct: 1015 RQGYQLAEDGHTCTDIDECAQGAGILCTFRCLNVPGSYQCACPEQGYTMTANGRSCKDVD 1074
Query: 922 ECVNNT-VCDSHGFCDNTAGSFRCLCYQ 948
EC T C C N GSFRCL ++
Sbjct: 1075 ECALGTHNCSEAETCHNIQGSFRCLRFE 1102
Score = 239 bits (609), Expect = 2e-62
Identities = 175/513 (34%), Positives = 237/513 (46%), Gaps = 89/513 (17%)
Query: 590 DIDECTQVQHLCSQGRCENTEGSFLCICPAGFMASEEGTNC----------IDVDECLR- 638
D DEC + Q C NT GS+ C C GF ++G C + L+
Sbjct: 604 DQDECLLLPGELCQHLCINTVGSYHCACFPGFSLQDDGRTCRPEGHPPQPEAPQEPALKS 663
Query: 639 ----------------PDVCGE-GHC---VNTVGAFRCEYCDSGYRMTQRG-RCEDIDEC 677
P+ C + G C +TVG C GY + G CED DEC
Sbjct: 664 EFSQVASNTIPLPLPQPNTCKDNGPCKQVCSTVGGSAICSCFPGYAIMADGVSCEDQDEC 723
Query: 678 L-NPSTCPDEQ-CVNSPGSYQCVP----CTEGF-RGWNGQCLDVDECL-EPNVCANGD-C 728
L C Q CVN+ GS+ CV C +G+ + +C+D++EC+ + + C+ G+ C
Sbjct: 724 LMGAHDCSRRQFCVNTLGSFYCVNHTVLCADGYILNAHRKCVDINECVTDLHTCSRGEHC 783
Query: 729 SNLEGSYMC----SCHKGYTRTPDHKHCRDIDECQQG-NLCVNG-QCKNTEGSFRCT--- 779
N GS+ C +C GY C D+DEC G + C G C+NT+GSF C
Sbjct: 784 VNTLGSFHCYKALTCEPGYALKDGE--CEDVDECAMGTHTCQPGFLCQNTKGSFYCQARQ 841
Query: 780 -CGQGYQLSAAKDQCEDIDECQH-RHLCAHG-QCRNTEGSFQC-----VCDQGYRASGLG 831
C G+ L + C DI+EC C G C NT GS+ C +C +GY AS G
Sbjct: 842 RCMDGF-LQDPEGNCVDINECTSLSEPCRPGFSCINTVGSYTCQRNPLICARGYHASDDG 900
Query: 832 DHCEDINECLEDKSVCQRGD-CINTAGSYDCTCPDGFQLDD-NKTCQDINEC-EHPG-LC 887
C D+NEC C G C N GSY C C GFQ D + C D+NEC PG LC
Sbjct: 901 TKCVDVNECETGVHRCGEGQVCHNLPGSYRCDCKAGFQRDAFGRGCIDVNECWASPGRLC 960
Query: 888 GPQGECLNTEGSFHCVCQQGFSISADGRTCEDIDECVNNTVCDSHGFCDNTAGSFRCLCY 947
Q C NT GS+ C C GF ++ADG+ CED++EC C N GS++C C
Sbjct: 961 --QHTCENTLGSYRCSCASGFLLAADGKRCEDVNECEAQRCSQE---CANIYGSYQCYCR 1015
Query: 948 QGFQAPQDGQGCVDVNECELLSGVCGEAFCENVEGSFLCVCADENQEYSPMTGQCRSRTS 1007
QG+Q +DG C D++EC +G+ C NV GS+ C C ++ + C+
Sbjct: 1016 QGYQLAEDGHTCTDIDECAQGAGILCTFRCLNVPGSYQCACPEQGYTMTANGRSCK---- 1071
Query: 1008 TDLDVDVDQPKEEKKEC---YYNLNDASLCDNV 1037
DVD EC +N ++A C N+
Sbjct: 1072 ---DVD---------ECALGTHNCSEAETCHNI 1092
Score = 142 bits (358), Expect = 2e-33
Identities = 85/230 (36%), Positives = 118/230 (51%), Gaps = 17/230 (7%)
Query: 544 TQVTEINECTVNPDICGAGH-CINLPVRYTCICYEGYRFSEQQRKCVDIDECTQVQHLCS 602
T+ ++NEC CG G C NLP Y C C G++ R C+D++EC
Sbjct: 901 TKCVDVNECETGVHRCGEGQVCHNLPGSYRCDCKAGFQRDAFGRGCIDVNECWASPGRLC 960
Query: 603 QGRCENTEGSFLCICPAGFMASEEGTNCIDVDECLRPDVCGEGHCVNTVGAFRCEYCDSG 662
Q CENT GS+ C C +GF+ + +G C DV+EC C + C N G+++C YC G
Sbjct: 961 QHTCENTLGSYRCSCASGFLLAADGKRCEDVNEC-EAQRCSQ-ECANIYGSYQC-YCRQG 1017
Query: 663 YRMTQRGR-CEDIDECL-NPSTCPDEQCVNSPGSYQCVPCTEGF-RGWNGQ-CLDVDEC- 717
Y++ + G C DIDEC +C+N PGSYQC +G+ NG+ C DVDEC
Sbjct: 1018 YQLAEDGHTCTDIDECAQGAGILCTFRCLNVPGSYQCACPEQGYTMTANGRSCKDVDECA 1077
Query: 718 LEPNVCANGD-CSNLEGSYMC---SCHKGYTRTPDHK----HCRDIDECQ 759
L + C+ + C N++GS+ C C Y + K C D ECQ
Sbjct: 1078 LGTHNCSEAETCHNIQGSFRCLRFECPPNYVQVSKTKCERTTCHDFLECQ 1127
Score = 138 bits (347), Expect = 4e-32
Identities = 193/758 (25%), Positives = 254/758 (33%), Gaps = 190/758 (25%)
Query: 708 NGQCLDVDEC-LEPNVCANGDCSNLEGSYMC--SCHKGYTRTPDHKHC--RDIDECQQGN 762
N +CL++ E E NVC + SY+ SC G + + C D D C
Sbjct: 456 NDECLEIPESGTEDNVCRTAQ-RHCCVSYLQEKSCMAGVLGAKEGETCGAEDNDSC---G 511
Query: 763 LCVNGQCKNTEGSFRCTCGQGYQLSAAKDQCEDIDECQHRHLCAHGQCRNTEGSFQCVCD 822
+ + QC + CG G ++ A CE + C H EG +
Sbjct: 512 ISLYKQCCDC-------CGLGLRVRAEGQSCESNPNLGYP--CNHVMLSCCEGEEPLIVP 562
Query: 823 Q--------------------GYRASGLGDHCE--------DINECLEDKSVCQRGDCIN 854
+ G A LG E D +ECL + CIN
Sbjct: 563 EVRRPPEPAAAPRRVSEAEMAGREALSLGTEAELPNSLPGDDQDECLLLPGELCQHLCIN 622
Query: 855 TAGSYDCTCPDGFQL-DDNKTCQ---------------------------------DINE 880
T GSY C C GF L DD +TC+ N
Sbjct: 623 TVGSYHCACFPGFSLQDDGRTCRPEGHPPQPEAPQEPALKSEFSQVASNTIPLPLPQPNT 682
Query: 881 CEHPGLCGPQGECLNTEGSFHCVCQQGFSISADGRTCEDIDECVNNTV-CDSHGFCDNTA 939
C+ G C + C GS C C G++I ADG +CED DEC+ C FC NT
Sbjct: 683 CKDNGPC--KQVCSTVGGSAICSCFPGYAIMADGVSCEDQDECLMGAHDCSRRQFCVNTL 740
Query: 940 GSFRC-----LCYQGFQAPQDGQGCVDVNECELLSGVCGEA-FCENVEGSFLCVCADENQ 993
GSF C LC G+ + CVD+NEC C C N GSF C A +
Sbjct: 741 GSFYCVNHTVLCADGYILNAHRK-CVDINECVTDLHTCSRGEHCVNTLGSFHCYKALTCE 799
Query: 994 E-YSPMTGQCRSRTSTDLDVDVDQPK---EEKKECYYNLNDASLCDNVLAPN----VTKQ 1045
Y+ G+C + QP + K +Y D L V
Sbjct: 800 PGYALKDGECEDVDECAMGTHTCQPGFLCQNTKGSFYCQARQRCMDGFLQDPEGNCVDIN 859
Query: 1046 ECCCTSGAGWGDNCEI-FPCPVLGTAEFTEMCPKGKGFVPAGESSSEAGGENYKDADECL 1104
EC S + C F C + +T C + G +S+ G D +EC
Sbjct: 860 ECTSLS-----EPCRPGFSC-INTVGSYT--CQRNPLICARGYHASD-DGTKCVDVNECE 910
Query: 1105 LFGQEICKNGFCLNTRPG-YECYCKQGTYYDPVKLQCFDMDEC-QDPSSCIDGQCVNTEG 1162
G C G + PG Y C CK G D C D++EC P C NT G
Sbjct: 911 T-GVHRCGEGQVCHNLPGSYRCDCKAGFQRDAFGRGCIDVNECWASPGRLCQHTCENTLG 969
Query: 1163 SYNCFCTHPMVLDASEKRCIRPAESNEQIEETDVYQDLCWEHLSDEYVCSRPLVGKQTTY 1222
SY C C +L A KRC E + E + + CS+ +Y
Sbjct: 970 SYRCSCASGFLLAADGKRC-------EDVNECEAQR------------CSQECANIYGSY 1010
Query: 1223 TECCCLYGEAWGMQCALCPLKDSDDYAQLCNIPVTGRRQPYGRDALVDFSEQYTPEADPY 1282
+C C G C D D+ AQ I T R
Sbjct: 1011 -QCYCRQGYQLAEDGHTC--TDIDECAQGAGILCTFR----------------------- 1044
Query: 1283 FIQDRFLNSFEELQAEECGILNGCENGRCVRVQEGYTCDCFD-GYHLDTAKMTCVDVNEC 1341
C+ V Y C C + GY + +C DV+EC
Sbjct: 1045 ----------------------------CLNVPGSYQCACPEQGYTMTANGRSCKDVDEC 1076
Query: 1342 DELNNRMSLCKNAKCINTDGSYKCL---CLPGYVPSDK 1376
+ S + C N GS++CL C P YV K
Sbjct: 1077 ALGTHNCSEAET--CHNIQGSFRCLRFECPPNYVQVSK 1112
Score = 87.0 bits (214), Expect = 1e-16
Identities = 104/442 (23%), Positives = 170/442 (38%), Gaps = 71/442 (16%)
Query: 961 DVNECELLSGVCGEAFCENVEGSFLCVCADENQEYSPMTGQCRSRTSTDLDVDVDQPKEE 1020
D +EC LL G + C N GS+ C C + + Q RT + QP E
Sbjct: 604 DQDECLLLPGELCQHLCINTVGSYHCAC------FPGFSLQDDGRTCRP-EGHPPQP-EA 655
Query: 1021 KKECYYNLNDASLCDNVLAPNVTKQECCCTSGAGWGDNCEIFPCP-VLGTAEFTEMCPKG 1079
+E + + N + + + C +G PC V T + +C
Sbjct: 656 PQEPALKSEFSQVASNTIPLPLPQPNTCKDNG----------PCKQVCSTVGGSAICSCF 705
Query: 1080 KGFVPAGESSSEAGGENYKDADECLLFGQEICKNGFCLNTRPGYECY-----CKQGTYYD 1134
G+ + A G + +D DECL+ + + FC+NT + C C G Y
Sbjct: 706 PGY------AIMADGVSCEDQDECLMGAHDCSRRQFCVNTLGSFYCVNHTVLCADG-YIL 758
Query: 1135 PVKLQCFDMDEC-QDPSSCIDGQ-CVNTEGSYNCFCTHPMVLDASEKRCIRPAESNEQIE 1192
+C D++EC D +C G+ CVNT GS++C+ L ++ E E ++
Sbjct: 759 NAHRKCVDINECVTDLHTCSRGEHCVNTLGSFHCY----KALTCEPGYALKDGEC-EDVD 813
Query: 1193 ETDVYQDLCWEHLSDEYVCSRPLVGKQTTYTECC--CLYGEAWGMQCALCPLKDSDDYAQ 1250
E + C ++C K + Y + C+ G + + + ++
Sbjct: 814 ECAMGTHTC----QPGFLCQNT---KGSFYCQARQRCMDGFLQDPEGNCVDINECTSLSE 866
Query: 1251 LCNIPVTGRRQPYGRDALVDFSEQYTPEADPYFIQDRFLNSFEELQAEECGILNGCENGR 1310
C + ++ YT + +P + S + +C +N CE G
Sbjct: 867 PCRPGFS----------CINTVGSYTCQRNPLICARGYHASDD---GTKCVDVNECETGV 913
Query: 1311 --------CVRVQEGYTCDCFDGYHLDTAKMTCVDVNECDELNNRMSLCKNAKCINTDGS 1362
C + Y CDC G+ D C+DVNEC R LC++ C NT GS
Sbjct: 914 HRCGEGQVCHNLPGSYRCDCKAGFQRDAFGRGCIDVNECWASPGR--LCQHT-CENTLGS 970
Query: 1363 YKCLCLPGYVPSDKPNYCTPLN 1384
Y+C C G++ + C +N
Sbjct: 971 YRCSCASGFLLAADGKRCEDVN 992
Score = 55.8 bits (133), Expect = 3e-07
Identities = 50/150 (33%), Positives = 62/150 (41%), Gaps = 37/150 (24%)
Query: 247 PGLSKQEDCCGTVGTSWGFNKCQKCPKKPSYHGYNQMMECLPGYKRVNN-TFCQDINECQ 305
PG S C TVG+ CQ+ P + C GY ++ T C D+NEC+
Sbjct: 870 PGFS----CINTVGSY----TCQRNP-----------LICARGYHASDDGTKCVDVNECE 910
Query: 306 LQGV--CPNGE-CLNTMGSYRCTCKIGFGPDPTFSSCVPDPPVISEEKGPCYRLVSSGRQ 362
GV C G+ C N GSYRC CK GF D C+ + C+ S GR
Sbjct: 911 T-GVHRCGEGQVCHNLPGSYRCDCKAGFQRDAFGRGCI--------DVNECW--ASPGRL 959
Query: 363 CMHPLSVHLTKQLCCCSVG---KAWGPHCE 389
C H L C C+ G A G CE
Sbjct: 960 CQHTCENTLGSYRCSCASGFLLAADGKRCE 989
Score = 42.7 bits (99), Expect = 0.002
Identities = 37/119 (31%), Positives = 50/119 (42%), Gaps = 15/119 (12%)
Query: 237 TIGS-QCGKAL---PGLSKQEDCCGTVGT-SWGFNKCQK---CPKKPSYHGYNQMMECLP 288
T+GS C KAL PG + ++ C V + G + CQ C C+
Sbjct: 786 TLGSFHCYKALTCEPGYALKDGECEDVDECAMGTHTCQPGFLCQNTKGSFYCQARQRCMD 845
Query: 289 GYKRVNNTFCQDINEC-QLQGVC-PNGECLNTMGSYRC-----TCKIGFGPDPTFSSCV 340
G+ + C DINEC L C P C+NT+GSY C C G+ + CV
Sbjct: 846 GFLQDPEGNCVDINECTSLSEPCRPGFSCINTVGSYTCQRNPLICARGYHASDDGTKCV 904
Score = 40.8 bits (94), Expect = 0.009
Identities = 28/96 (29%), Positives = 42/96 (43%), Gaps = 21/96 (21%)
Query: 241 QCGKALPGLSKQEDCCGTVGTSWGFNKCQKCPKKPSYHGYNQMMECLPGYKRVNNTFCQD 300
+C S+++ C T+G S++ N + C GY + C D
Sbjct: 722 ECLMGAHDCSRRQFCVNTLG---------------SFYCVNHTVLCADGYILNAHRKCVD 766
Query: 301 INECQLQ-GVCPNGE-CLNTMGSYRC----TCKIGF 330
INEC C GE C+NT+GS+ C TC+ G+
Sbjct: 767 INECVTDLHTCSRGEHCVNTLGSFHCYKALTCEPGY 802
Score = 39.3 bits (90), Expect = 0.027
Identities = 30/111 (27%), Positives = 48/111 (43%), Gaps = 18/111 (16%)
Query: 236 ETIGSQCGKA-----LPGLSKQEDCCGTVGTSWG-----FNKCQKCPKKPSYHGYNQMM- 284
ET +CG+ LPG + + G ++G N+C P + H +
Sbjct: 910 ETGVHRCGEGQVCHNLPGSYRCDCKAGFQRDAFGRGCIDVNECWASPGRLCQHTCENTLG 969
Query: 285 ----ECLPGYK-RVNNTFCQDINECQLQGVCPNGECLNTMGSYRCTCKIGF 330
C G+ + C+D+NEC+ Q + EC N GSY+C C+ G+
Sbjct: 970 SYRCSCASGFLLAADGKRCEDVNECEAQRC--SQECANIYGSYQCYCRQGY 1018
Score = 37.4 bits (85), Expect = 0.10
Identities = 31/103 (30%), Positives = 45/103 (43%), Gaps = 21/103 (20%)
Query: 245 ALPGLSKQEDCCGTVGT-----SWGF------------NKC--QKCPKKPSYHGYNQMME 285
A PG Q C T+G+ + GF N+C Q+C ++ + +
Sbjct: 954 ASPGRLCQHTCENTLGSYRCSCASGFLLAADGKRCEDVNECEAQRCSQECANIYGSYQCY 1013
Query: 286 CLPGYKRVNNTF-CQDINEC-QLQGVCPNGECLNTMGSYRCTC 326
C GY+ + C DI+EC Q G+ CLN GSY+C C
Sbjct: 1014 CRQGYQLAEDGHTCTDIDECAQGAGILCTFRCLNVPGSYQCAC 1056
Score = 34.7 bits (78), Expect = 0.66
Identities = 31/109 (28%), Positives = 45/109 (41%), Gaps = 8/109 (7%)
Query: 300 DINECQL-QGVCPNGECLNTMGSYRCTCKIGFGPDPTFSSCVPD--PPVISEEKGPCYRL 356
D +EC L G C+NT+GSY C C GF +C P+ PP + P +
Sbjct: 604 DQDECLLLPGELCQHLCINTVGSYHCACFPGFSLQDDGRTCRPEGHPPQPEAPQEPALKS 663
Query: 357 VSSGRQCMHPLSVHLTKQLCCCSVGKAWGPHCEKCPLPGTAAFKEICPG 405
S + + + + L + C K GP + C G +A PG
Sbjct: 664 EFS-QVASNTIPLPLPQPNTC----KDNGPCKQVCSTVGGSAICSCFPG 707
>gi|34734064 fibulin 1 isoform B precursor [Homo sapiens]
Length = 601
Score = 256 bits (655), Expect = 8e-68
Identities = 151/377 (40%), Positives = 203/377 (53%), Gaps = 36/377 (9%)
Query: 601 CSQGRCENTEGSFLCICPAGFMASEEGTNCIDVDECLR-PDVCGEGH-CVNTVGAFRCE- 657
C Q +C +T +C C G+ +G +C DV+EC+ C G C+NTVG+FRC+
Sbjct: 186 CKQ-QCRDTGDEVVCSCFVGYQLLSDGVSCEDVNECITGSHSCRLGESCINTVGSFRCQR 244
Query: 658 --YCDSGYRMTQRGRCEDIDECLN--PSTCPDEQCVNSPGSYQCVP---CTEGF-RGWNG 709
C +GY +T+ C+DIDEC + + PD C N+ GS++C P C GF + G
Sbjct: 245 DSSCGTGYELTEDNSCKDIDECESGIHNCLPDFICQNTLGSFRCRPKLQCKSGFIQDALG 304
Query: 710 QCLDVDECLEPNV-CANG-DCSNLEGSYMC-----SCHKGYTRTPDHKHCRDIDEC-QQG 761
C+D++ECL + C G C N EGSY C +C +GY + C D+DEC
Sbjct: 305 NCIDINECLSISAPCPIGHTCINTEGSYTCQKNVPNCGRGYHLNEEGTRCVDVDECAPPA 364
Query: 762 NLCVNG-QCKNTEGSFRCTCGQGYQLSAAKDQCEDIDECQH--RHLCAHGQCRNTEGSFQ 818
C G +C N+ GSFRC C GY C D++ECQ LC H +C NT GS+
Sbjct: 365 EPCGKGHRCVNSPGSFRCECKTGYYFDGISRMCVDVNECQRYPGRLCGH-KCENTLGSYL 423
Query: 819 CVCDQGYRASGLGDHCEDINECLEDKSVCQRGDCINTAGSYDCTCPDGFQLD--DNKTCQ 876
C C G+R S G CEDINEC S C + +C N GSY C C G+QL D TC+
Sbjct: 424 CSCSVGFRLSVDGRSCEDINEC--SSSPCSQ-ECANVYGSYQCYCRRGYQLSDVDGVTCE 480
Query: 877 DINECEHP---GLCGPQGECLNTEGSFHCVC-QQGFSISADGRTCEDIDECVNNT-VCDS 931
DI+EC P +C + C+N GSF C C G+ ++ +GR C+DIDECV C
Sbjct: 481 DIDECALPTGGHICSYR--CINIPGSFQCSCPSSGYRLAPNGRNCQDIDECVTGIHNCSI 538
Query: 932 HGFCDNTAGSFRCLCYQ 948
+ C N G FRCL ++
Sbjct: 539 NETCFNIQGGFRCLAFE 555
Score = 223 bits (568), Expect = 1e-57
Identities = 152/412 (36%), Positives = 207/412 (50%), Gaps = 54/412 (13%)
Query: 545 QVTEINECTVNP---DICGAG-----HCINLPVRYTCICYEGYRFSEQQRKCVDIDECTQ 596
++ E+ E +P D C G C + C C+ GY+ C D++EC
Sbjct: 163 KIIEVEEEQEDPYLNDRCRGGGPCKQQCRDTGDEVVCSCFVGYQLLSDGVSCEDVNECIT 222
Query: 597 VQHLCSQGR-CENTEGSFLC----ICPAGFMASEEGTNCIDVDEC------LRPDVCGEG 645
H C G C NT GSF C C G+ +E+ +C D+DEC PD
Sbjct: 223 GSHSCRLGESCINTVGSFRCQRDSSCGTGYELTED-NSCKDIDECESGIHNCLPDFI--- 278
Query: 646 HCVNTVGAFRCE---YCDSGYRMTQRGRCEDIDECLNPST-CP-DEQCVNSPGSYQC--- 697
C NT+G+FRC C SG+ G C DI+ECL+ S CP C+N+ GSY C
Sbjct: 279 -CQNTLGSFRCRPKLQCKSGFIQDALGNCIDINECLSISAPCPIGHTCINTEGSYTCQKN 337
Query: 698 VP-CTEGF--RGWNGQCLDVDECLEP-NVCANGD-CSNLEGSYMCSCHKGYTRTPDHKHC 752
VP C G+ +C+DVDEC P C G C N GS+ C C GY + C
Sbjct: 338 VPNCGRGYHLNEEGTRCVDVDECAPPAEPCGKGHRCVNSPGSFRCECKTGYYFDGISRMC 397
Query: 753 RDIDECQQ--GNLCVNGQCKNTEGSFRCTCGQGYQLSAAKDQCEDIDECQHRHLCAHGQC 810
D++ECQ+ G LC +C+NT GS+ C+C G++LS CEDI+EC C+ +C
Sbjct: 398 VDVNECQRYPGRLC-GHKCENTLGSYLCSCSVGFRLSVDGRSCEDINECSSSP-CSQ-EC 454
Query: 811 RNTEGSFQCVCDQGYRASGL-GDHCEDINECL--EDKSVCQRGDCINTAGSYDCTCP-DG 866
N GS+QC C +GY+ S + G CEDI+EC +C CIN GS+ C+CP G
Sbjct: 455 ANVYGSYQCYCRRGYQLSDVDGVTCEDIDECALPTGGHICSY-RCINIPGSFQCSCPSSG 513
Query: 867 FQLDDN-KTCQDINECEHPGL--CGPQGECLNTEGSFHCV---CQQGFSISA 912
++L N + CQDI+EC G+ C C N +G F C+ C + + SA
Sbjct: 514 YRLAPNGRNCQDIDECV-TGIHNCSINETCFNIQGGFRCLAFECPENYRRSA 564
Score = 168 bits (425), Expect = 4e-41
Identities = 173/630 (27%), Positives = 239/630 (37%), Gaps = 133/630 (21%)
Query: 565 INLPVRYTCICYEGYRFSEQQRKC-----VDIDECTQVQHLCSQGRCENTEGSFLCICPA 619
++ V C +G+R + Q+ C + EC VQ C + E C
Sbjct: 27 VDADVLLEACCADGHRMATHQKDCSLPYATESKECRMVQEQCCHSQLEELH------CAT 80
Query: 620 GFMASEEGTNCIDVDECLRPDVCGEGHCVNTVGAFRCEYCDSGYRMTQRGRCEDIDECLN 679
G + E D C P G+ + RC +C R Q
Sbjct: 81 GISLANEQ------DRCATPH--GDNASLEATFVKRCCHCCLLGRAAQA----------Q 122
Query: 680 PSTCPDEQCVNSPGSYQCVPCTEGFRGWNGQCLDVDECLEPNVCANGDCSNLEGSYMCSC 739
+C V YQC + FR C++ + D L+ +
Sbjct: 123 GQSCEYSLMVG----YQC---GQVFRAC---------CVKSQETGDLDVGGLQET----- 161
Query: 740 HKGYTRTPDHKHCRDIDECQQGNLCVNGQCKNTEGSFRCTCGQGYQLSAAKDQCEDIDEC 799
K + + D C+ G C QC++T C+C GYQL + CED++EC
Sbjct: 162 DKIIEVEEEQEDPYLNDRCRGGGPCKQ-QCRDTGDEVVCSCFVGYQLLSDGVSCEDVNEC 220
Query: 800 -QHRHLCAHGQ-CRNTEGSFQCV----CDQGYRASGLGDHCEDINECLEDKSVCQRGD-C 852
H C G+ C NT GSF+C C GY + + C+DI+EC C C
Sbjct: 221 ITGSHSCRLGESCINTVGSFRCQRDSSCGTGYELTE-DNSCKDIDECESGIHNCLPDFIC 279
Query: 853 INTAGSYDCT----CPDGFQLDDNKTCQDINECEHPGLCGPQGE-CLNTEGSFHCV---- 903
NT GS+ C C GF D C DINEC P G C+NTEGS+ C
Sbjct: 280 QNTLGSFRCRPKLQCKSGFIQDALGNCIDINECLSISAPCPIGHTCINTEGSYTCQKNVP 339
Query: 904 -CQQGFSISADGRTCEDIDECVNNTV-CDSHGFCDNTAGSFRCLCYQGFQAPQDGQGCVD 961
C +G+ ++ +G C D+DEC C C N+ GSFRC C G+ + CVD
Sbjct: 340 NCGRGYHLNEEGTRCVDVDECAPPAEPCGKGHRCVNSPGSFRCECKTGYYFDGISRMCVD 399
Query: 962 VNECELLSG-VCGEAFCENVEGSFLCVCADENQEYSPMTGQCRSRTSTDLDVDVDQPKEE 1020
VNEC+ G +CG CEN GS+LC C+ L VD + E+
Sbjct: 400 VNECQRYPGRLCGHK-CENTLGSYLCSCS----------------VGFRLSVD-GRSCED 441
Query: 1021 KKECYYNLNDASLCDNVLAPNVTKQECCCTSGAGWGDNCEIFPCPVLGTAEFTEMCPKGK 1080
EC +S C QEC G+ + C
Sbjct: 442 INEC-----SSSPC---------SQECANVYGS--------YQC---------------- 463
Query: 1081 GFVPAGESSSEAGGENYKDADECLL-FGQEICKNGFCLNTRPGYECYCKQGTY-YDPVKL 1138
+ G S+ G +D DEC L G IC C+N ++C C Y P
Sbjct: 464 -YCRRGYQLSDVDGVTCEDIDECALPTGGHICSYR-CINIPGSFQCSCPSSGYRLAPNGR 521
Query: 1139 QCFDMDECQD--PSSCIDGQCVNTEGSYNC 1166
C D+DEC + I+ C N +G + C
Sbjct: 522 NCQDIDECVTGIHNCSINETCFNIQGGFRC 551
Score = 147 bits (370), Expect = 9e-35
Identities = 81/216 (37%), Positives = 118/216 (54%), Gaps = 17/216 (7%)
Query: 544 TQVTEINECTVNPDICGAGH-CINLPVRYTCICYEGYRFSEQQRKCVDIDECTQVQHLCS 602
T+ +++EC + CG GH C+N P + C C GY F R CVD++EC +
Sbjct: 352 TRCVDVDECAPPAEPCGKGHRCVNSPGSFRCECKTGYYFDGISRMCVDVNECQRYPGRLC 411
Query: 603 QGRCENTEGSFLCICPAGFMASEEGTNCIDVDECLRPDVCGEGHCVNTVGAFRCEYCDSG 662
+CENT GS+LC C GF S +G +C D++EC C + C N G+++C YC G
Sbjct: 412 GHKCENTLGSYLCSCSVGFRLSVDGRSCEDINEC-SSSPCSQ-ECANVYGSYQC-YCRRG 468
Query: 663 YRMTQRG--RCEDIDECLNPS---TCPDEQCVNSPGSYQCVPCTEGFR-GWNGQ-CLDVD 715
Y+++ CEDIDEC P+ C +C+N PGS+QC + G+R NG+ C D+D
Sbjct: 469 YQLSDVDGVTCEDIDECALPTGGHIC-SYRCINIPGSFQCSCPSSGYRLAPNGRNCQDID 527
Query: 716 ECLE--PNVCANGDCSNLEGSYMC---SCHKGYTRT 746
EC+ N N C N++G + C C + Y R+
Sbjct: 528 ECVTGIHNCSINETCFNIQGGFRCLAFECPENYRRS 563
Score = 101 bits (251), Expect = 6e-21
Identities = 115/426 (26%), Positives = 162/426 (38%), Gaps = 70/426 (16%)
Query: 921 DECVNNTVCDSHGFCDNTAGSFRCLCYQGFQAPQDGQGCVDVNECELLSGVC--GEAFCE 978
D C C C +T C C+ G+Q DG C DVNEC S C GE+ C
Sbjct: 178 DRCRGGGPCKQQ--CRDTGDEVVCSCFVGYQLLSDGVSCEDVNECITGSHSCRLGES-CI 234
Query: 979 NVEGSFLCVCADENQEYSPMTGQCRSRTSTDLDVDVDQPKEEKKECYYNLNDASLCDNVL 1038
N GSF C ++ S TG + ++ D+D E + +N +C N L
Sbjct: 235 NTVGSFRC-----QRDSSCGTGYELTEDNSCKDID------ECESGIHNCLPDFICQNTL 283
Query: 1039 APNVTKQECCCTSGA---GWGDNCEI-------FPCPVLGTAEFTE---MCPKGKGFVPA 1085
+ + C SG G+ +I PCP+ T TE C K
Sbjct: 284 GSFRCRPKLQCKSGFIQDALGNCIDINECLSISAPCPIGHTCINTEGSYTCQKNVPNCGR 343
Query: 1086 GESSSEAGGENYKDADECLLFGQEICKNGFCLNTRPGYECYCKQGTYYDPVKLQCFDMDE 1145
G +E G D DEC + K C+N+ + C CK G Y+D + C D++E
Sbjct: 344 GYHLNEEG-TRCVDVDECAPPAEPCGKGHRCVNSPGSFRCECKTGYYFDGISRMCVDVNE 402
Query: 1146 CQD-PSSCIDGQCVNTEGSYNCFCTHPMVLDASEKRCIRPAESNEQIEETDVYQDLCWEH 1204
CQ P +C NT GSY C C+ L + C E I E
Sbjct: 403 CQRYPGRLCGHKCENTLGSYLCSCSVGFRLSVDGRSC-------EDINE----------- 444
Query: 1205 LSDEYVCSRPLVGKQTTYTECCCLYG----EAWGMQCALCPLKDSDDYAQLCNIPVTGRR 1260
CS+ +Y +C C G + G+ C +D D+ C +P G
Sbjct: 445 -CSSSPCSQECANVYGSY-QCYCRRGYQLSDVDGVTC-----EDIDE----CALPTGGHI 493
Query: 1261 QPYGRDALVDFSEQYTPEADPYFIQDRFLNSFEELQAEEC--GILNGCENGRCVRVQEGY 1318
Y R + S Q + + Y + N + +EC GI N N C +Q G+
Sbjct: 494 CSY-RCINIPGSFQCSCPSSGYRLAPNGRNCQD---IDECVTGIHNCSINETCFNIQGGF 549
Query: 1319 TCDCFD 1324
C F+
Sbjct: 550 RCLAFE 555
Score = 66.2 bits (160), Expect = 2e-10
Identities = 80/293 (27%), Positives = 107/293 (36%), Gaps = 63/293 (21%)
Query: 1116 CLNTRPGYECYCKQGTYYDPVKLQCFDMDECQDPS-SCIDGQ-CVNTEGSYNCFCTHPMV 1173
C +T C C G + C D++EC S SC G+ C+NT GS+ C
Sbjct: 190 CRDTGDEVVCSCFVGYQLLSDGVSCEDVNECITGSHSCRLGESCINTVGSFRC------- 242
Query: 1174 LDASEKRCIRPAESNEQIEETDVYQDLCWEHLSD---EYVCSRPLVGKQTTYTECCCLYG 1230
+ C E E D+ D C + + +++C L G + C G
Sbjct: 243 --QRDSSCGTGYELTEDNSCKDI--DECESGIHNCLPDFICQNTL-GSFRCRPKLQCKSG 297
Query: 1231 ---EAWGM-----QC----ALCPL-----KDSDDYAQLCNIPVTGRRQPYGRDAL--VDF 1271
+A G +C A CP+ Y N+P GR + VD
Sbjct: 298 FIQDALGNCIDINECLSISAPCPIGHTCINTEGSYTCQKNVPNCGRGYHLNEEGTRCVDV 357
Query: 1272 SEQYTPEADPYFIQDRFLNSFEELQAEECGILNGCENGRCVRVQEGYTCDCFDGYHLDTA 1331
E P AE CG + RCV + C+C GY+ D
Sbjct: 358 DECAPP-------------------AEPCG-----KGHRCVNSPGSFRCECKTGYYFDGI 393
Query: 1332 KMTCVDVNECDELNNRMSLCKNAKCINTDGSYKCLCLPGYVPSDKPNYCTPLN 1384
CVDVNEC R LC + KC NT GSY C C G+ S C +N
Sbjct: 394 SRMCVDVNECQRYPGR--LCGH-KCENTLGSYLCSCSVGFRLSVDGRSCEDIN 443
Score = 60.5 bits (145), Expect = 1e-08
Identities = 133/557 (23%), Positives = 182/557 (32%), Gaps = 173/557 (31%)
Query: 860 DCTCPDGFQLDDNKTCQDINECEHPGLCGPQGECLNTEGSFHCVCQQGFSISADGRTCED 919
DC+ P ++K C+ + E C Q E L+ C G S++ + C
Sbjct: 49 DCSLP---YATESKECRMVQE----QCCHSQLEELH--------CATGISLANEQDRC-- 91
Query: 920 IDECVNNTVCDSHGFCDNTAGSF--RCL--CYQGFQAPQDGQGCVDVNECELLSGV-CGE 974
HG + +F RC C G A GQ C E L+ G CG+
Sbjct: 92 ---------ATPHGDNASLEATFVKRCCHCCLLGRAAQAQGQSC----EYSLMVGYQCGQ 138
Query: 975 AFCENVEGSFLCVCADENQEYSPMTGQCRSRTSTDLDVDVDQPKEEKKECYYNLNDASLC 1034
F C ++QE TG DLDV Q ++ E D L
Sbjct: 139 VFR---------ACCVKSQE----TG--------DLDVGGLQETDKIIEVEEEQEDPYLN 177
Query: 1035 DNVLAPNVTKQECCCTSGAGWGDNCEIFPCPVLGTAEFTEMCPKGKGFVPAGESSSEAGG 1094
D KQ+C T GD E C G + G S
Sbjct: 178 DRCRGGGPCKQQCRDT-----GD-------------EVVCSCFVGYQLLSDGVSC----- 214
Query: 1095 ENYKDADECLLFGQEICKNG-FCLNTRPGYECYCKQ--GTYYDPVK-LQCFDMDECQDP- 1149
+D +EC+ G C+ G C+NT + C GT Y+ + C D+DEC+
Sbjct: 215 ---EDVNECIT-GSHSCRLGESCINTVGSFRCQRDSSCGTGYELTEDNSCKDIDECESGI 270
Query: 1150 SSCI-DGQCVNTEGSYNCF----CTHPMVLDASEKRCIRPAESNEQIEETDVYQDLCWEH 1204
+C+ D C NT GS+ C C + DA
Sbjct: 271 HNCLPDFICQNTLGSFRCRPKLQCKSGFIQDA---------------------------- 302
Query: 1205 LSDEYVCSRPLVGKQTTYTECCCLYGEAWGMQCALCPL-----KDSDDYAQLCNIPVTGR 1259
+G EC + A CP+ Y N+P GR
Sbjct: 303 -----------LGNCIDINECLSI--------SAPCPIGHTCINTEGSYTCQKNVPNCGR 343
Query: 1260 RQPYGRDAL--VDFSEQYTPEADPYFIQDRFLNSFEELQAE------------ECGILNG 1305
+ VD E P A+P R +NS + E C +N
Sbjct: 344 GYHLNEEGTRCVDVDE-CAPPAEPCGKGHRCVNSPGSFRCECKTGYYFDGISRMCVDVNE 402
Query: 1306 CEN-------GRCVRVQEGYTCDCFDGYHLDTAKMTCVDVNECDELNNRMSLCKNAKCIN 1358
C+ +C Y C C G+ L +C D+NEC S C +C N
Sbjct: 403 CQRYPGRLCGHKCENTLGSYLCSCSVGFRLSVDGRSCEDINECSS-----SPCSQ-ECAN 456
Query: 1359 TDGSYKCLCLPGYVPSD 1375
GSY+C C GY SD
Sbjct: 457 VYGSYQCYCRRGYQLSD 473
Score = 50.1 bits (118), Expect = 2e-05
Identities = 37/109 (33%), Positives = 45/109 (41%), Gaps = 13/109 (11%)
Query: 276 SYHGYNQMMECLPGYK-RVNNTFCQDINECQLQGV-CPNGE-CLNTMGSYRCTCKIGFGP 332
SY + C GY T C D++EC C G C+N+ GS+RC CK G+
Sbjct: 331 SYTCQKNVPNCGRGYHLNEEGTRCVDVDECAPPAEPCGKGHRCVNSPGSFRCECKTGYYF 390
Query: 333 DPTFSSCVPDPPVISEEKGPCYRLVSSGRQCMHPLSVHLTKQLCCCSVG 381
D CV + C R GR C H L LC CSVG
Sbjct: 391 DGISRMCV--------DVNECQRY--PGRLCGHKCENTLGSYLCSCSVG 429
Score = 43.5 bits (101), Expect = 0.001
Identities = 29/94 (30%), Positives = 43/94 (45%), Gaps = 23/94 (24%)
Query: 253 EDCCGTVGTSWGFNKCQKCPKKPSYHGYNQMMECLPGYKRVNNTFCQDINECQ--LQGVC 310
E C TVG+ +C + S C GY+ + C+DI+EC+ +
Sbjct: 231 ESCINTVGSF-------RCQRDSS---------CGTGYELTEDNSCKDIDECESGIHNCL 274
Query: 311 PNGECLNTMGSYRC----TCKIGFGPDPTFSSCV 340
P+ C NT+GS+RC CK GF D +C+
Sbjct: 275 PDFICQNTLGSFRCRPKLQCKSGFIQD-ALGNCI 307
Score = 42.4 bits (98), Expect = 0.003
Identities = 23/57 (40%), Positives = 29/57 (50%), Gaps = 2/57 (3%)
Query: 285 ECLPGYKRVN-NTFCQDINECQ-LQGVCPNGECLNTMGSYRCTCKIGFGPDPTFSSC 339
EC GY + C D+NECQ G +C NT+GSY C+C +GF SC
Sbjct: 383 ECKTGYYFDGISRMCVDVNECQRYPGRLCGHKCENTLGSYLCSCSVGFRLSVDGRSC 439
Score = 42.4 bits (98), Expect = 0.003
Identities = 24/71 (33%), Positives = 35/71 (49%), Gaps = 8/71 (11%)
Query: 266 NKCQKCPKKPSYHGYNQMM-----ECLPGYK-RVNNTFCQDINECQLQGVCPNGECLNTM 319
N+CQ+ P + H + C G++ V+ C+DINEC C EC N
Sbjct: 401 NECQRYPGRLCGHKCENTLGSYLCSCSVGFRLSVDGRSCEDINECS-SSPCSQ-ECANVY 458
Query: 320 GSYRCTCKIGF 330
GSY+C C+ G+
Sbjct: 459 GSYQCYCRRGY 469
Score = 34.3 bits (77), Expect = 0.86
Identities = 20/59 (33%), Positives = 31/59 (52%), Gaps = 5/59 (8%)
Query: 286 CLPGYKR--VNNTFCQDINECQLQ--GVCPNGECLNTMGSYRCTC-KIGFGPDPTFSSC 339
C GY+ V+ C+DI+EC L G + C+N GS++C+C G+ P +C
Sbjct: 465 CRRGYQLSDVDGVTCEDIDECALPTGGHICSYRCINIPGSFQCSCPSSGYRLAPNGRNC 523
>gi|34734068 fibulin 1 isoform A precursor [Homo sapiens]
Length = 566
Score = 256 bits (655), Expect = 8e-68
Identities = 151/377 (40%), Positives = 203/377 (53%), Gaps = 36/377 (9%)
Query: 601 CSQGRCENTEGSFLCICPAGFMASEEGTNCIDVDECLR-PDVCGEGH-CVNTVGAFRCE- 657
C Q +C +T +C C G+ +G +C DV+EC+ C G C+NTVG+FRC+
Sbjct: 186 CKQ-QCRDTGDEVVCSCFVGYQLLSDGVSCEDVNECITGSHSCRLGESCINTVGSFRCQR 244
Query: 658 --YCDSGYRMTQRGRCEDIDECLN--PSTCPDEQCVNSPGSYQCVP---CTEGF-RGWNG 709
C +GY +T+ C+DIDEC + + PD C N+ GS++C P C GF + G
Sbjct: 245 DSSCGTGYELTEDNSCKDIDECESGIHNCLPDFICQNTLGSFRCRPKLQCKSGFIQDALG 304
Query: 710 QCLDVDECLEPNV-CANG-DCSNLEGSYMC-----SCHKGYTRTPDHKHCRDIDEC-QQG 761
C+D++ECL + C G C N EGSY C +C +GY + C D+DEC
Sbjct: 305 NCIDINECLSISAPCPIGHTCINTEGSYTCQKNVPNCGRGYHLNEEGTRCVDVDECAPPA 364
Query: 762 NLCVNG-QCKNTEGSFRCTCGQGYQLSAAKDQCEDIDECQH--RHLCAHGQCRNTEGSFQ 818
C G +C N+ GSFRC C GY C D++ECQ LC H +C NT GS+
Sbjct: 365 EPCGKGHRCVNSPGSFRCECKTGYYFDGISRMCVDVNECQRYPGRLCGH-KCENTLGSYL 423
Query: 819 CVCDQGYRASGLGDHCEDINECLEDKSVCQRGDCINTAGSYDCTCPDGFQLD--DNKTCQ 876
C C G+R S G CEDINEC S C + +C N GSY C C G+QL D TC+
Sbjct: 424 CSCSVGFRLSVDGRSCEDINEC--SSSPCSQ-ECANVYGSYQCYCRRGYQLSDVDGVTCE 480
Query: 877 DINECEHP---GLCGPQGECLNTEGSFHCVC-QQGFSISADGRTCEDIDECVNNT-VCDS 931
DI+EC P +C + C+N GSF C C G+ ++ +GR C+DIDECV C
Sbjct: 481 DIDECALPTGGHICSYR--CINIPGSFQCSCPSSGYRLAPNGRNCQDIDECVTGIHNCSI 538
Query: 932 HGFCDNTAGSFRCLCYQ 948
+ C N G FRCL ++
Sbjct: 539 NETCFNIQGGFRCLAFE 555
Score = 223 bits (568), Expect = 1e-57
Identities = 152/412 (36%), Positives = 207/412 (50%), Gaps = 54/412 (13%)
Query: 545 QVTEINECTVNP---DICGAG-----HCINLPVRYTCICYEGYRFSEQQRKCVDIDECTQ 596
++ E+ E +P D C G C + C C+ GY+ C D++EC
Sbjct: 163 KIIEVEEEQEDPYLNDRCRGGGPCKQQCRDTGDEVVCSCFVGYQLLSDGVSCEDVNECIT 222
Query: 597 VQHLCSQGR-CENTEGSFLC----ICPAGFMASEEGTNCIDVDEC------LRPDVCGEG 645
H C G C NT GSF C C G+ +E+ +C D+DEC PD
Sbjct: 223 GSHSCRLGESCINTVGSFRCQRDSSCGTGYELTED-NSCKDIDECESGIHNCLPDFI--- 278
Query: 646 HCVNTVGAFRCE---YCDSGYRMTQRGRCEDIDECLNPST-CP-DEQCVNSPGSYQC--- 697
C NT+G+FRC C SG+ G C DI+ECL+ S CP C+N+ GSY C
Sbjct: 279 -CQNTLGSFRCRPKLQCKSGFIQDALGNCIDINECLSISAPCPIGHTCINTEGSYTCQKN 337
Query: 698 VP-CTEGF--RGWNGQCLDVDECLEP-NVCANGD-CSNLEGSYMCSCHKGYTRTPDHKHC 752
VP C G+ +C+DVDEC P C G C N GS+ C C GY + C
Sbjct: 338 VPNCGRGYHLNEEGTRCVDVDECAPPAEPCGKGHRCVNSPGSFRCECKTGYYFDGISRMC 397
Query: 753 RDIDECQQ--GNLCVNGQCKNTEGSFRCTCGQGYQLSAAKDQCEDIDECQHRHLCAHGQC 810
D++ECQ+ G LC +C+NT GS+ C+C G++LS CEDI+EC C+ +C
Sbjct: 398 VDVNECQRYPGRLC-GHKCENTLGSYLCSCSVGFRLSVDGRSCEDINECSSSP-CSQ-EC 454
Query: 811 RNTEGSFQCVCDQGYRASGL-GDHCEDINECL--EDKSVCQRGDCINTAGSYDCTCP-DG 866
N GS+QC C +GY+ S + G CEDI+EC +C CIN GS+ C+CP G
Sbjct: 455 ANVYGSYQCYCRRGYQLSDVDGVTCEDIDECALPTGGHICSY-RCINIPGSFQCSCPSSG 513
Query: 867 FQLDDN-KTCQDINECEHPGL--CGPQGECLNTEGSFHCV---CQQGFSISA 912
++L N + CQDI+EC G+ C C N +G F C+ C + + SA
Sbjct: 514 YRLAPNGRNCQDIDECV-TGIHNCSINETCFNIQGGFRCLAFECPENYRRSA 564
Score = 168 bits (425), Expect = 4e-41
Identities = 173/630 (27%), Positives = 239/630 (37%), Gaps = 133/630 (21%)
Query: 565 INLPVRYTCICYEGYRFSEQQRKC-----VDIDECTQVQHLCSQGRCENTEGSFLCICPA 619
++ V C +G+R + Q+ C + EC VQ C + E C
Sbjct: 27 VDADVLLEACCADGHRMATHQKDCSLPYATESKECRMVQEQCCHSQLEELH------CAT 80
Query: 620 GFMASEEGTNCIDVDECLRPDVCGEGHCVNTVGAFRCEYCDSGYRMTQRGRCEDIDECLN 679
G + E D C P G+ + RC +C R Q
Sbjct: 81 GISLANEQ------DRCATPH--GDNASLEATFVKRCCHCCLLGRAAQA----------Q 122
Query: 680 PSTCPDEQCVNSPGSYQCVPCTEGFRGWNGQCLDVDECLEPNVCANGDCSNLEGSYMCSC 739
+C V YQC + FR C++ + D L+ +
Sbjct: 123 GQSCEYSLMVG----YQC---GQVFRAC---------CVKSQETGDLDVGGLQET----- 161
Query: 740 HKGYTRTPDHKHCRDIDECQQGNLCVNGQCKNTEGSFRCTCGQGYQLSAAKDQCEDIDEC 799
K + + D C+ G C QC++T C+C GYQL + CED++EC
Sbjct: 162 DKIIEVEEEQEDPYLNDRCRGGGPCKQ-QCRDTGDEVVCSCFVGYQLLSDGVSCEDVNEC 220
Query: 800 -QHRHLCAHGQ-CRNTEGSFQCV----CDQGYRASGLGDHCEDINECLEDKSVCQRGD-C 852
H C G+ C NT GSF+C C GY + + C+DI+EC C C
Sbjct: 221 ITGSHSCRLGESCINTVGSFRCQRDSSCGTGYELTE-DNSCKDIDECESGIHNCLPDFIC 279
Query: 853 INTAGSYDCT----CPDGFQLDDNKTCQDINECEHPGLCGPQGE-CLNTEGSFHCV---- 903
NT GS+ C C GF D C DINEC P G C+NTEGS+ C
Sbjct: 280 QNTLGSFRCRPKLQCKSGFIQDALGNCIDINECLSISAPCPIGHTCINTEGSYTCQKNVP 339
Query: 904 -CQQGFSISADGRTCEDIDECVNNTV-CDSHGFCDNTAGSFRCLCYQGFQAPQDGQGCVD 961
C +G+ ++ +G C D+DEC C C N+ GSFRC C G+ + CVD
Sbjct: 340 NCGRGYHLNEEGTRCVDVDECAPPAEPCGKGHRCVNSPGSFRCECKTGYYFDGISRMCVD 399
Query: 962 VNECELLSG-VCGEAFCENVEGSFLCVCADENQEYSPMTGQCRSRTSTDLDVDVDQPKEE 1020
VNEC+ G +CG CEN GS+LC C+ L VD + E+
Sbjct: 400 VNECQRYPGRLCGHK-CENTLGSYLCSCS----------------VGFRLSVD-GRSCED 441
Query: 1021 KKECYYNLNDASLCDNVLAPNVTKQECCCTSGAGWGDNCEIFPCPVLGTAEFTEMCPKGK 1080
EC +S C QEC G+ + C
Sbjct: 442 INEC-----SSSPC---------SQECANVYGS--------YQC---------------- 463
Query: 1081 GFVPAGESSSEAGGENYKDADECLL-FGQEICKNGFCLNTRPGYECYCKQGTY-YDPVKL 1138
+ G S+ G +D DEC L G IC C+N ++C C Y P
Sbjct: 464 -YCRRGYQLSDVDGVTCEDIDECALPTGGHICSYR-CINIPGSFQCSCPSSGYRLAPNGR 521
Query: 1139 QCFDMDECQD--PSSCIDGQCVNTEGSYNC 1166
C D+DEC + I+ C N +G + C
Sbjct: 522 NCQDIDECVTGIHNCSINETCFNIQGGFRC 551
Score = 147 bits (370), Expect = 9e-35
Identities = 81/216 (37%), Positives = 118/216 (54%), Gaps = 17/216 (7%)
Query: 544 TQVTEINECTVNPDICGAGH-CINLPVRYTCICYEGYRFSEQQRKCVDIDECTQVQHLCS 602
T+ +++EC + CG GH C+N P + C C GY F R CVD++EC +
Sbjct: 352 TRCVDVDECAPPAEPCGKGHRCVNSPGSFRCECKTGYYFDGISRMCVDVNECQRYPGRLC 411
Query: 603 QGRCENTEGSFLCICPAGFMASEEGTNCIDVDECLRPDVCGEGHCVNTVGAFRCEYCDSG 662
+CENT GS+LC C GF S +G +C D++EC C + C N G+++C YC G
Sbjct: 412 GHKCENTLGSYLCSCSVGFRLSVDGRSCEDINEC-SSSPCSQ-ECANVYGSYQC-YCRRG 468
Query: 663 YRMTQRG--RCEDIDECLNPS---TCPDEQCVNSPGSYQCVPCTEGFR-GWNGQ-CLDVD 715
Y+++ CEDIDEC P+ C +C+N PGS+QC + G+R NG+ C D+D
Sbjct: 469 YQLSDVDGVTCEDIDECALPTGGHIC-SYRCINIPGSFQCSCPSSGYRLAPNGRNCQDID 527
Query: 716 ECLE--PNVCANGDCSNLEGSYMC---SCHKGYTRT 746
EC+ N N C N++G + C C + Y R+
Sbjct: 528 ECVTGIHNCSINETCFNIQGGFRCLAFECPENYRRS 563
Score = 101 bits (251), Expect = 6e-21
Identities = 115/426 (26%), Positives = 162/426 (38%), Gaps = 70/426 (16%)
Query: 921 DECVNNTVCDSHGFCDNTAGSFRCLCYQGFQAPQDGQGCVDVNECELLSGVC--GEAFCE 978
D C C C +T C C+ G+Q DG C DVNEC S C GE+ C
Sbjct: 178 DRCRGGGPCKQQ--CRDTGDEVVCSCFVGYQLLSDGVSCEDVNECITGSHSCRLGES-CI 234
Query: 979 NVEGSFLCVCADENQEYSPMTGQCRSRTSTDLDVDVDQPKEEKKECYYNLNDASLCDNVL 1038
N GSF C ++ S TG + ++ D+D E + +N +C N L
Sbjct: 235 NTVGSFRC-----QRDSSCGTGYELTEDNSCKDID------ECESGIHNCLPDFICQNTL 283
Query: 1039 APNVTKQECCCTSGA---GWGDNCEI-------FPCPVLGTAEFTE---MCPKGKGFVPA 1085
+ + C SG G+ +I PCP+ T TE C K
Sbjct: 284 GSFRCRPKLQCKSGFIQDALGNCIDINECLSISAPCPIGHTCINTEGSYTCQKNVPNCGR 343
Query: 1086 GESSSEAGGENYKDADECLLFGQEICKNGFCLNTRPGYECYCKQGTYYDPVKLQCFDMDE 1145
G +E G D DEC + K C+N+ + C CK G Y+D + C D++E
Sbjct: 344 GYHLNEEG-TRCVDVDECAPPAEPCGKGHRCVNSPGSFRCECKTGYYFDGISRMCVDVNE 402
Query: 1146 CQD-PSSCIDGQCVNTEGSYNCFCTHPMVLDASEKRCIRPAESNEQIEETDVYQDLCWEH 1204
CQ P +C NT GSY C C+ L + C E I E
Sbjct: 403 CQRYPGRLCGHKCENTLGSYLCSCSVGFRLSVDGRSC-------EDINE----------- 444
Query: 1205 LSDEYVCSRPLVGKQTTYTECCCLYG----EAWGMQCALCPLKDSDDYAQLCNIPVTGRR 1260
CS+ +Y +C C G + G+ C +D D+ C +P G
Sbjct: 445 -CSSSPCSQECANVYGSY-QCYCRRGYQLSDVDGVTC-----EDIDE----CALPTGGHI 493
Query: 1261 QPYGRDALVDFSEQYTPEADPYFIQDRFLNSFEELQAEEC--GILNGCENGRCVRVQEGY 1318
Y R + S Q + + Y + N + +EC GI N N C +Q G+
Sbjct: 494 CSY-RCINIPGSFQCSCPSSGYRLAPNGRNCQD---IDECVTGIHNCSINETCFNIQGGF 549
Query: 1319 TCDCFD 1324
C F+
Sbjct: 550 RCLAFE 555
Score = 66.2 bits (160), Expect = 2e-10
Identities = 80/293 (27%), Positives = 107/293 (36%), Gaps = 63/293 (21%)
Query: 1116 CLNTRPGYECYCKQGTYYDPVKLQCFDMDECQDPS-SCIDGQ-CVNTEGSYNCFCTHPMV 1173
C +T C C G + C D++EC S SC G+ C+NT GS+ C
Sbjct: 190 CRDTGDEVVCSCFVGYQLLSDGVSCEDVNECITGSHSCRLGESCINTVGSFRC------- 242
Query: 1174 LDASEKRCIRPAESNEQIEETDVYQDLCWEHLSD---EYVCSRPLVGKQTTYTECCCLYG 1230
+ C E E D+ D C + + +++C L G + C G
Sbjct: 243 --QRDSSCGTGYELTEDNSCKDI--DECESGIHNCLPDFICQNTL-GSFRCRPKLQCKSG 297
Query: 1231 ---EAWGM-----QC----ALCPL-----KDSDDYAQLCNIPVTGRRQPYGRDAL--VDF 1271
+A G +C A CP+ Y N+P GR + VD
Sbjct: 298 FIQDALGNCIDINECLSISAPCPIGHTCINTEGSYTCQKNVPNCGRGYHLNEEGTRCVDV 357
Query: 1272 SEQYTPEADPYFIQDRFLNSFEELQAEECGILNGCENGRCVRVQEGYTCDCFDGYHLDTA 1331
E P AE CG + RCV + C+C GY+ D
Sbjct: 358 DECAPP-------------------AEPCG-----KGHRCVNSPGSFRCECKTGYYFDGI 393
Query: 1332 KMTCVDVNECDELNNRMSLCKNAKCINTDGSYKCLCLPGYVPSDKPNYCTPLN 1384
CVDVNEC R LC + KC NT GSY C C G+ S C +N
Sbjct: 394 SRMCVDVNECQRYPGR--LCGH-KCENTLGSYLCSCSVGFRLSVDGRSCEDIN 443
Score = 60.5 bits (145), Expect = 1e-08
Identities = 133/557 (23%), Positives = 182/557 (32%), Gaps = 173/557 (31%)
Query: 860 DCTCPDGFQLDDNKTCQDINECEHPGLCGPQGECLNTEGSFHCVCQQGFSISADGRTCED 919
DC+ P ++K C+ + E C Q E L+ C G S++ + C
Sbjct: 49 DCSLP---YATESKECRMVQE----QCCHSQLEELH--------CATGISLANEQDRC-- 91
Query: 920 IDECVNNTVCDSHGFCDNTAGSF--RCL--CYQGFQAPQDGQGCVDVNECELLSGV-CGE 974
HG + +F RC C G A GQ C E L+ G CG+
Sbjct: 92 ---------ATPHGDNASLEATFVKRCCHCCLLGRAAQAQGQSC----EYSLMVGYQCGQ 138
Query: 975 AFCENVEGSFLCVCADENQEYSPMTGQCRSRTSTDLDVDVDQPKEEKKECYYNLNDASLC 1034
F C ++QE TG DLDV Q ++ E D L
Sbjct: 139 VFR---------ACCVKSQE----TG--------DLDVGGLQETDKIIEVEEEQEDPYLN 177
Query: 1035 DNVLAPNVTKQECCCTSGAGWGDNCEIFPCPVLGTAEFTEMCPKGKGFVPAGESSSEAGG 1094
D KQ+C T GD E C G + G S
Sbjct: 178 DRCRGGGPCKQQCRDT-----GD-------------EVVCSCFVGYQLLSDGVSC----- 214
Query: 1095 ENYKDADECLLFGQEICKNG-FCLNTRPGYECYCKQ--GTYYDPVK-LQCFDMDECQDP- 1149
+D +EC+ G C+ G C+NT + C GT Y+ + C D+DEC+
Sbjct: 215 ---EDVNECIT-GSHSCRLGESCINTVGSFRCQRDSSCGTGYELTEDNSCKDIDECESGI 270
Query: 1150 SSCI-DGQCVNTEGSYNCF----CTHPMVLDASEKRCIRPAESNEQIEETDVYQDLCWEH 1204
+C+ D C NT GS+ C C + DA
Sbjct: 271 HNCLPDFICQNTLGSFRCRPKLQCKSGFIQDA---------------------------- 302
Query: 1205 LSDEYVCSRPLVGKQTTYTECCCLYGEAWGMQCALCPL-----KDSDDYAQLCNIPVTGR 1259
+G EC + A CP+ Y N+P GR
Sbjct: 303 -----------LGNCIDINECLSI--------SAPCPIGHTCINTEGSYTCQKNVPNCGR 343
Query: 1260 RQPYGRDAL--VDFSEQYTPEADPYFIQDRFLNSFEELQAE------------ECGILNG 1305
+ VD E P A+P R +NS + E C +N
Sbjct: 344 GYHLNEEGTRCVDVDE-CAPPAEPCGKGHRCVNSPGSFRCECKTGYYFDGISRMCVDVNE 402
Query: 1306 CEN-------GRCVRVQEGYTCDCFDGYHLDTAKMTCVDVNECDELNNRMSLCKNAKCIN 1358
C+ +C Y C C G+ L +C D+NEC S C +C N
Sbjct: 403 CQRYPGRLCGHKCENTLGSYLCSCSVGFRLSVDGRSCEDINECSS-----SPCSQ-ECAN 456
Query: 1359 TDGSYKCLCLPGYVPSD 1375
GSY+C C GY SD
Sbjct: 457 VYGSYQCYCRRGYQLSD 473
Score = 50.1 bits (118), Expect = 2e-05
Identities = 37/109 (33%), Positives = 45/109 (41%), Gaps = 13/109 (11%)
Query: 276 SYHGYNQMMECLPGYK-RVNNTFCQDINECQLQGV-CPNGE-CLNTMGSYRCTCKIGFGP 332
SY + C GY T C D++EC C G C+N+ GS+RC CK G+
Sbjct: 331 SYTCQKNVPNCGRGYHLNEEGTRCVDVDECAPPAEPCGKGHRCVNSPGSFRCECKTGYYF 390
Query: 333 DPTFSSCVPDPPVISEEKGPCYRLVSSGRQCMHPLSVHLTKQLCCCSVG 381
D CV + C R GR C H L LC CSVG
Sbjct: 391 DGISRMCV--------DVNECQRY--PGRLCGHKCENTLGSYLCSCSVG 429
Score = 43.5 bits (101), Expect = 0.001
Identities = 29/94 (30%), Positives = 43/94 (45%), Gaps = 23/94 (24%)
Query: 253 EDCCGTVGTSWGFNKCQKCPKKPSYHGYNQMMECLPGYKRVNNTFCQDINECQ--LQGVC 310
E C TVG+ +C + S C GY+ + C+DI+EC+ +
Sbjct: 231 ESCINTVGSF-------RCQRDSS---------CGTGYELTEDNSCKDIDECESGIHNCL 274
Query: 311 PNGECLNTMGSYRC----TCKIGFGPDPTFSSCV 340
P+ C NT+GS+RC CK GF D +C+
Sbjct: 275 PDFICQNTLGSFRCRPKLQCKSGFIQD-ALGNCI 307
Score = 42.4 bits (98), Expect = 0.003
Identities = 23/57 (40%), Positives = 29/57 (50%), Gaps = 2/57 (3%)
Query: 285 ECLPGYKRVN-NTFCQDINECQ-LQGVCPNGECLNTMGSYRCTCKIGFGPDPTFSSC 339
EC GY + C D+NECQ G +C NT+GSY C+C +GF SC
Sbjct: 383 ECKTGYYFDGISRMCVDVNECQRYPGRLCGHKCENTLGSYLCSCSVGFRLSVDGRSC 439
Score = 42.4 bits (98), Expect = 0.003
Identities = 24/71 (33%), Positives = 35/71 (49%), Gaps = 8/71 (11%)
Query: 266 NKCQKCPKKPSYHGYNQMM-----ECLPGYK-RVNNTFCQDINECQLQGVCPNGECLNTM 319
N+CQ+ P + H + C G++ V+ C+DINEC C EC N
Sbjct: 401 NECQRYPGRLCGHKCENTLGSYLCSCSVGFRLSVDGRSCEDINECS-SSPCSQ-ECANVY 458
Query: 320 GSYRCTCKIGF 330
GSY+C C+ G+
Sbjct: 459 GSYQCYCRRGY 469
Score = 34.3 bits (77), Expect = 0.86
Identities = 20/59 (33%), Positives = 31/59 (52%), Gaps = 5/59 (8%)
Query: 286 CLPGYKR--VNNTFCQDINECQLQ--GVCPNGECLNTMGSYRCTC-KIGFGPDPTFSSC 339
C GY+ V+ C+DI+EC L G + C+N GS++C+C G+ P +C
Sbjct: 465 CRRGYQLSDVDGVTCEDIDECALPTGGHICSYRCINIPGSFQCSCPSSGYRLAPNGRNC 523
>gi|34734066 fibulin 1 isoform D [Homo sapiens]
Length = 703
Score = 256 bits (655), Expect = 8e-68
Identities = 151/377 (40%), Positives = 203/377 (53%), Gaps = 36/377 (9%)
Query: 601 CSQGRCENTEGSFLCICPAGFMASEEGTNCIDVDECLR-PDVCGEGH-CVNTVGAFRCE- 657
C Q +C +T +C C G+ +G +C DV+EC+ C G C+NTVG+FRC+
Sbjct: 186 CKQ-QCRDTGDEVVCSCFVGYQLLSDGVSCEDVNECITGSHSCRLGESCINTVGSFRCQR 244
Query: 658 --YCDSGYRMTQRGRCEDIDECLN--PSTCPDEQCVNSPGSYQCVP---CTEGF-RGWNG 709
C +GY +T+ C+DIDEC + + PD C N+ GS++C P C GF + G
Sbjct: 245 DSSCGTGYELTEDNSCKDIDECESGIHNCLPDFICQNTLGSFRCRPKLQCKSGFIQDALG 304
Query: 710 QCLDVDECLEPNV-CANG-DCSNLEGSYMC-----SCHKGYTRTPDHKHCRDIDEC-QQG 761
C+D++ECL + C G C N EGSY C +C +GY + C D+DEC
Sbjct: 305 NCIDINECLSISAPCPIGHTCINTEGSYTCQKNVPNCGRGYHLNEEGTRCVDVDECAPPA 364
Query: 762 NLCVNG-QCKNTEGSFRCTCGQGYQLSAAKDQCEDIDECQH--RHLCAHGQCRNTEGSFQ 818
C G +C N+ GSFRC C GY C D++ECQ LC H +C NT GS+
Sbjct: 365 EPCGKGHRCVNSPGSFRCECKTGYYFDGISRMCVDVNECQRYPGRLCGH-KCENTLGSYL 423
Query: 819 CVCDQGYRASGLGDHCEDINECLEDKSVCQRGDCINTAGSYDCTCPDGFQLD--DNKTCQ 876
C C G+R S G CEDINEC S C + +C N GSY C C G+QL D TC+
Sbjct: 424 CSCSVGFRLSVDGRSCEDINEC--SSSPCSQ-ECANVYGSYQCYCRRGYQLSDVDGVTCE 480
Query: 877 DINECEHP---GLCGPQGECLNTEGSFHCVC-QQGFSISADGRTCEDIDECVNNT-VCDS 931
DI+EC P +C + C+N GSF C C G+ ++ +GR C+DIDECV C
Sbjct: 481 DIDECALPTGGHICSYR--CINIPGSFQCSCPSSGYRLAPNGRNCQDIDECVTGIHNCSI 538
Query: 932 HGFCDNTAGSFRCLCYQ 948
+ C N G FRCL ++
Sbjct: 539 NETCFNIQGGFRCLAFE 555
Score = 223 bits (568), Expect = 1e-57
Identities = 152/412 (36%), Positives = 207/412 (50%), Gaps = 54/412 (13%)
Query: 545 QVTEINECTVNP---DICGAG-----HCINLPVRYTCICYEGYRFSEQQRKCVDIDECTQ 596
++ E+ E +P D C G C + C C+ GY+ C D++EC
Sbjct: 163 KIIEVEEEQEDPYLNDRCRGGGPCKQQCRDTGDEVVCSCFVGYQLLSDGVSCEDVNECIT 222
Query: 597 VQHLCSQGR-CENTEGSFLC----ICPAGFMASEEGTNCIDVDEC------LRPDVCGEG 645
H C G C NT GSF C C G+ +E+ +C D+DEC PD
Sbjct: 223 GSHSCRLGESCINTVGSFRCQRDSSCGTGYELTED-NSCKDIDECESGIHNCLPDFI--- 278
Query: 646 HCVNTVGAFRCE---YCDSGYRMTQRGRCEDIDECLNPST-CP-DEQCVNSPGSYQC--- 697
C NT+G+FRC C SG+ G C DI+ECL+ S CP C+N+ GSY C
Sbjct: 279 -CQNTLGSFRCRPKLQCKSGFIQDALGNCIDINECLSISAPCPIGHTCINTEGSYTCQKN 337
Query: 698 VP-CTEGF--RGWNGQCLDVDECLEP-NVCANGD-CSNLEGSYMCSCHKGYTRTPDHKHC 752
VP C G+ +C+DVDEC P C G C N GS+ C C GY + C
Sbjct: 338 VPNCGRGYHLNEEGTRCVDVDECAPPAEPCGKGHRCVNSPGSFRCECKTGYYFDGISRMC 397
Query: 753 RDIDECQQ--GNLCVNGQCKNTEGSFRCTCGQGYQLSAAKDQCEDIDECQHRHLCAHGQC 810
D++ECQ+ G LC +C+NT GS+ C+C G++LS CEDI+EC C+ +C
Sbjct: 398 VDVNECQRYPGRLC-GHKCENTLGSYLCSCSVGFRLSVDGRSCEDINECSSSP-CSQ-EC 454
Query: 811 RNTEGSFQCVCDQGYRASGL-GDHCEDINECL--EDKSVCQRGDCINTAGSYDCTCP-DG 866
N GS+QC C +GY+ S + G CEDI+EC +C CIN GS+ C+CP G
Sbjct: 455 ANVYGSYQCYCRRGYQLSDVDGVTCEDIDECALPTGGHICSY-RCINIPGSFQCSCPSSG 513
Query: 867 FQLDDN-KTCQDINECEHPGL--CGPQGECLNTEGSFHCV---CQQGFSISA 912
++L N + CQDI+EC G+ C C N +G F C+ C + + SA
Sbjct: 514 YRLAPNGRNCQDIDECV-TGIHNCSINETCFNIQGGFRCLAFECPENYRRSA 564
Score = 168 bits (425), Expect = 4e-41
Identities = 173/630 (27%), Positives = 239/630 (37%), Gaps = 133/630 (21%)
Query: 565 INLPVRYTCICYEGYRFSEQQRKC-----VDIDECTQVQHLCSQGRCENTEGSFLCICPA 619
++ V C +G+R + Q+ C + EC VQ C + E C
Sbjct: 27 VDADVLLEACCADGHRMATHQKDCSLPYATESKECRMVQEQCCHSQLEELH------CAT 80
Query: 620 GFMASEEGTNCIDVDECLRPDVCGEGHCVNTVGAFRCEYCDSGYRMTQRGRCEDIDECLN 679
G + E D C P G+ + RC +C R Q
Sbjct: 81 GISLANEQ------DRCATPH--GDNASLEATFVKRCCHCCLLGRAAQA----------Q 122
Query: 680 PSTCPDEQCVNSPGSYQCVPCTEGFRGWNGQCLDVDECLEPNVCANGDCSNLEGSYMCSC 739
+C V YQC + FR C++ + D L+ +
Sbjct: 123 GQSCEYSLMVG----YQC---GQVFRAC---------CVKSQETGDLDVGGLQET----- 161
Query: 740 HKGYTRTPDHKHCRDIDECQQGNLCVNGQCKNTEGSFRCTCGQGYQLSAAKDQCEDIDEC 799
K + + D C+ G C QC++T C+C GYQL + CED++EC
Sbjct: 162 DKIIEVEEEQEDPYLNDRCRGGGPCKQ-QCRDTGDEVVCSCFVGYQLLSDGVSCEDVNEC 220
Query: 800 -QHRHLCAHGQ-CRNTEGSFQCV----CDQGYRASGLGDHCEDINECLEDKSVCQRGD-C 852
H C G+ C NT GSF+C C GY + + C+DI+EC C C
Sbjct: 221 ITGSHSCRLGESCINTVGSFRCQRDSSCGTGYELTE-DNSCKDIDECESGIHNCLPDFIC 279
Query: 853 INTAGSYDCT----CPDGFQLDDNKTCQDINECEHPGLCGPQGE-CLNTEGSFHCV---- 903
NT GS+ C C GF D C DINEC P G C+NTEGS+ C
Sbjct: 280 QNTLGSFRCRPKLQCKSGFIQDALGNCIDINECLSISAPCPIGHTCINTEGSYTCQKNVP 339
Query: 904 -CQQGFSISADGRTCEDIDECVNNTV-CDSHGFCDNTAGSFRCLCYQGFQAPQDGQGCVD 961
C +G+ ++ +G C D+DEC C C N+ GSFRC C G+ + CVD
Sbjct: 340 NCGRGYHLNEEGTRCVDVDECAPPAEPCGKGHRCVNSPGSFRCECKTGYYFDGISRMCVD 399
Query: 962 VNECELLSG-VCGEAFCENVEGSFLCVCADENQEYSPMTGQCRSRTSTDLDVDVDQPKEE 1020
VNEC+ G +CG CEN GS+LC C+ L VD + E+
Sbjct: 400 VNECQRYPGRLCGHK-CENTLGSYLCSCS----------------VGFRLSVD-GRSCED 441
Query: 1021 KKECYYNLNDASLCDNVLAPNVTKQECCCTSGAGWGDNCEIFPCPVLGTAEFTEMCPKGK 1080
EC +S C QEC G+ + C
Sbjct: 442 INEC-----SSSPC---------SQECANVYGS--------YQC---------------- 463
Query: 1081 GFVPAGESSSEAGGENYKDADECLL-FGQEICKNGFCLNTRPGYECYCKQGTY-YDPVKL 1138
+ G S+ G +D DEC L G IC C+N ++C C Y P
Sbjct: 464 -YCRRGYQLSDVDGVTCEDIDECALPTGGHICSYR-CINIPGSFQCSCPSSGYRLAPNGR 521
Query: 1139 QCFDMDECQD--PSSCIDGQCVNTEGSYNC 1166
C D+DEC + I+ C N +G + C
Sbjct: 522 NCQDIDECVTGIHNCSINETCFNIQGGFRC 551
Score = 147 bits (370), Expect = 9e-35
Identities = 81/216 (37%), Positives = 118/216 (54%), Gaps = 17/216 (7%)
Query: 544 TQVTEINECTVNPDICGAGH-CINLPVRYTCICYEGYRFSEQQRKCVDIDECTQVQHLCS 602
T+ +++EC + CG GH C+N P + C C GY F R CVD++EC +
Sbjct: 352 TRCVDVDECAPPAEPCGKGHRCVNSPGSFRCECKTGYYFDGISRMCVDVNECQRYPGRLC 411
Query: 603 QGRCENTEGSFLCICPAGFMASEEGTNCIDVDECLRPDVCGEGHCVNTVGAFRCEYCDSG 662
+CENT GS+LC C GF S +G +C D++EC C + C N G+++C YC G
Sbjct: 412 GHKCENTLGSYLCSCSVGFRLSVDGRSCEDINEC-SSSPCSQ-ECANVYGSYQC-YCRRG 468
Query: 663 YRMTQRG--RCEDIDECLNPS---TCPDEQCVNSPGSYQCVPCTEGFR-GWNGQ-CLDVD 715
Y+++ CEDIDEC P+ C +C+N PGS+QC + G+R NG+ C D+D
Sbjct: 469 YQLSDVDGVTCEDIDECALPTGGHIC-SYRCINIPGSFQCSCPSSGYRLAPNGRNCQDID 527
Query: 716 ECLE--PNVCANGDCSNLEGSYMC---SCHKGYTRT 746
EC+ N N C N++G + C C + Y R+
Sbjct: 528 ECVTGIHNCSINETCFNIQGGFRCLAFECPENYRRS 563
Score = 101 bits (252), Expect = 4e-21
Identities = 117/438 (26%), Positives = 166/438 (37%), Gaps = 73/438 (16%)
Query: 921 DECVNNTVCDSHGFCDNTAGSFRCLCYQGFQAPQDGQGCVDVNECELLSGVC--GEAFCE 978
D C C C +T C C+ G+Q DG C DVNEC S C GE+ C
Sbjct: 178 DRCRGGGPCKQQ--CRDTGDEVVCSCFVGYQLLSDGVSCEDVNECITGSHSCRLGES-CI 234
Query: 979 NVEGSFLCVCADENQEYSPMTGQCRSRTSTDLDVDVDQPKEEKKECYYNLNDASLCDNVL 1038
N GSF C ++ S TG + ++ D+D E + +N +C N L
Sbjct: 235 NTVGSFRC-----QRDSSCGTGYELTEDNSCKDID------ECESGIHNCLPDFICQNTL 283
Query: 1039 APNVTKQECCCTSGA---GWGDNCEI-------FPCPVLGTAEFTE---MCPKGKGFVPA 1085
+ + C SG G+ +I PCP+ T TE C K
Sbjct: 284 GSFRCRPKLQCKSGFIQDALGNCIDINECLSISAPCPIGHTCINTEGSYTCQKNVPNCGR 343
Query: 1086 GESSSEAGGENYKDADECLLFGQEICKNGFCLNTRPGYECYCKQGTYYDPVKLQCFDMDE 1145
G +E G D DEC + K C+N+ + C CK G Y+D + C D++E
Sbjct: 344 GYHLNEEG-TRCVDVDECAPPAEPCGKGHRCVNSPGSFRCECKTGYYFDGISRMCVDVNE 402
Query: 1146 CQD-PSSCIDGQCVNTEGSYNCFCTHPMVLDASEKRCIRPAESNEQIEETDVYQDLCWEH 1204
CQ P +C NT GSY C C+ L + C E I E
Sbjct: 403 CQRYPGRLCGHKCENTLGSYLCSCSVGFRLSVDGRSC-------EDINE----------- 444
Query: 1205 LSDEYVCSRPLVGKQTTYTECCCLYG----EAWGMQCALCPLKDSDDYAQLCNIPVTGRR 1260
CS+ +Y +C C G + G+ C +D D+ C +P G
Sbjct: 445 -CSSSPCSQECANVYGSY-QCYCRRGYQLSDVDGVTC-----EDIDE----CALPTGGHI 493
Query: 1261 QPYGRDALVDFSEQYTPEADPYFIQDRFLNSFEELQAEEC--GILNGCENGRCVRVQEGY 1318
Y R + S Q + + Y + N + +EC GI N N C +Q G+
Sbjct: 494 CSY-RCINIPGSFQCSCPSSGYRLAPNGRNCQD---IDECVTGIHNCSINETCFNIQGGF 549
Query: 1319 TC---DCFDGYHLDTAKM 1333
C +C + Y A +
Sbjct: 550 RCLAFECPENYRRSAATL 567
Score = 66.2 bits (160), Expect = 2e-10
Identities = 80/293 (27%), Positives = 107/293 (36%), Gaps = 63/293 (21%)
Query: 1116 CLNTRPGYECYCKQGTYYDPVKLQCFDMDECQDPS-SCIDGQ-CVNTEGSYNCFCTHPMV 1173
C +T C C G + C D++EC S SC G+ C+NT GS+ C
Sbjct: 190 CRDTGDEVVCSCFVGYQLLSDGVSCEDVNECITGSHSCRLGESCINTVGSFRC------- 242
Query: 1174 LDASEKRCIRPAESNEQIEETDVYQDLCWEHLSD---EYVCSRPLVGKQTTYTECCCLYG 1230
+ C E E D+ D C + + +++C L G + C G
Sbjct: 243 --QRDSSCGTGYELTEDNSCKDI--DECESGIHNCLPDFICQNTL-GSFRCRPKLQCKSG 297
Query: 1231 ---EAWGM-----QC----ALCPL-----KDSDDYAQLCNIPVTGRRQPYGRDAL--VDF 1271
+A G +C A CP+ Y N+P GR + VD
Sbjct: 298 FIQDALGNCIDINECLSISAPCPIGHTCINTEGSYTCQKNVPNCGRGYHLNEEGTRCVDV 357
Query: 1272 SEQYTPEADPYFIQDRFLNSFEELQAEECGILNGCENGRCVRVQEGYTCDCFDGYHLDTA 1331
E P AE CG + RCV + C+C GY+ D
Sbjct: 358 DECAPP-------------------AEPCG-----KGHRCVNSPGSFRCECKTGYYFDGI 393
Query: 1332 KMTCVDVNECDELNNRMSLCKNAKCINTDGSYKCLCLPGYVPSDKPNYCTPLN 1384
CVDVNEC R LC + KC NT GSY C C G+ S C +N
Sbjct: 394 SRMCVDVNECQRYPGR--LCGH-KCENTLGSYLCSCSVGFRLSVDGRSCEDIN 443
Score = 60.5 bits (145), Expect = 1e-08
Identities = 133/557 (23%), Positives = 182/557 (32%), Gaps = 173/557 (31%)
Query: 860 DCTCPDGFQLDDNKTCQDINECEHPGLCGPQGECLNTEGSFHCVCQQGFSISADGRTCED 919
DC+ P ++K C+ + E C Q E L+ C G S++ + C
Sbjct: 49 DCSLP---YATESKECRMVQE----QCCHSQLEELH--------CATGISLANEQDRC-- 91
Query: 920 IDECVNNTVCDSHGFCDNTAGSF--RCL--CYQGFQAPQDGQGCVDVNECELLSGV-CGE 974
HG + +F RC C G A GQ C E L+ G CG+
Sbjct: 92 ---------ATPHGDNASLEATFVKRCCHCCLLGRAAQAQGQSC----EYSLMVGYQCGQ 138
Query: 975 AFCENVEGSFLCVCADENQEYSPMTGQCRSRTSTDLDVDVDQPKEEKKECYYNLNDASLC 1034
F C ++QE TG DLDV Q ++ E D L
Sbjct: 139 VFR---------ACCVKSQE----TG--------DLDVGGLQETDKIIEVEEEQEDPYLN 177
Query: 1035 DNVLAPNVTKQECCCTSGAGWGDNCEIFPCPVLGTAEFTEMCPKGKGFVPAGESSSEAGG 1094
D KQ+C T GD E C G + G S
Sbjct: 178 DRCRGGGPCKQQCRDT-----GD-------------EVVCSCFVGYQLLSDGVSC----- 214
Query: 1095 ENYKDADECLLFGQEICKNG-FCLNTRPGYECYCKQ--GTYYDPVK-LQCFDMDECQDP- 1149
+D +EC+ G C+ G C+NT + C GT Y+ + C D+DEC+
Sbjct: 215 ---EDVNECIT-GSHSCRLGESCINTVGSFRCQRDSSCGTGYELTEDNSCKDIDECESGI 270
Query: 1150 SSCI-DGQCVNTEGSYNCF----CTHPMVLDASEKRCIRPAESNEQIEETDVYQDLCWEH 1204
+C+ D C NT GS+ C C + DA
Sbjct: 271 HNCLPDFICQNTLGSFRCRPKLQCKSGFIQDA---------------------------- 302
Query: 1205 LSDEYVCSRPLVGKQTTYTECCCLYGEAWGMQCALCPL-----KDSDDYAQLCNIPVTGR 1259
+G EC + A CP+ Y N+P GR
Sbjct: 303 -----------LGNCIDINECLSI--------SAPCPIGHTCINTEGSYTCQKNVPNCGR 343
Query: 1260 RQPYGRDAL--VDFSEQYTPEADPYFIQDRFLNSFEELQAE------------ECGILNG 1305
+ VD E P A+P R +NS + E C +N
Sbjct: 344 GYHLNEEGTRCVDVDE-CAPPAEPCGKGHRCVNSPGSFRCECKTGYYFDGISRMCVDVNE 402
Query: 1306 CEN-------GRCVRVQEGYTCDCFDGYHLDTAKMTCVDVNECDELNNRMSLCKNAKCIN 1358
C+ +C Y C C G+ L +C D+NEC S C +C N
Sbjct: 403 CQRYPGRLCGHKCENTLGSYLCSCSVGFRLSVDGRSCEDINECSS-----SPCSQ-ECAN 456
Query: 1359 TDGSYKCLCLPGYVPSD 1375
GSY+C C GY SD
Sbjct: 457 VYGSYQCYCRRGYQLSD 473
Score = 50.1 bits (118), Expect = 2e-05
Identities = 37/109 (33%), Positives = 45/109 (41%), Gaps = 13/109 (11%)
Query: 276 SYHGYNQMMECLPGYK-RVNNTFCQDINECQLQGV-CPNGE-CLNTMGSYRCTCKIGFGP 332
SY + C GY T C D++EC C G C+N+ GS+RC CK G+
Sbjct: 331 SYTCQKNVPNCGRGYHLNEEGTRCVDVDECAPPAEPCGKGHRCVNSPGSFRCECKTGYYF 390
Query: 333 DPTFSSCVPDPPVISEEKGPCYRLVSSGRQCMHPLSVHLTKQLCCCSVG 381
D CV + C R GR C H L LC CSVG
Sbjct: 391 DGISRMCV--------DVNECQRY--PGRLCGHKCENTLGSYLCSCSVG 429
Score = 43.5 bits (101), Expect = 0.001
Identities = 29/94 (30%), Positives = 43/94 (45%), Gaps = 23/94 (24%)
Query: 253 EDCCGTVGTSWGFNKCQKCPKKPSYHGYNQMMECLPGYKRVNNTFCQDINECQ--LQGVC 310
E C TVG+ +C + S C GY+ + C+DI+EC+ +
Sbjct: 231 ESCINTVGSF-------RCQRDSS---------CGTGYELTEDNSCKDIDECESGIHNCL 274
Query: 311 PNGECLNTMGSYRC----TCKIGFGPDPTFSSCV 340
P+ C NT+GS+RC CK GF D +C+
Sbjct: 275 PDFICQNTLGSFRCRPKLQCKSGFIQD-ALGNCI 307
Score = 42.4 bits (98), Expect = 0.003
Identities = 23/57 (40%), Positives = 29/57 (50%), Gaps = 2/57 (3%)
Query: 285 ECLPGYKRVN-NTFCQDINECQ-LQGVCPNGECLNTMGSYRCTCKIGFGPDPTFSSC 339
EC GY + C D+NECQ G +C NT+GSY C+C +GF SC
Sbjct: 383 ECKTGYYFDGISRMCVDVNECQRYPGRLCGHKCENTLGSYLCSCSVGFRLSVDGRSC 439
Score = 42.4 bits (98), Expect = 0.003
Identities = 24/71 (33%), Positives = 35/71 (49%), Gaps = 8/71 (11%)
Query: 266 NKCQKCPKKPSYHGYNQMM-----ECLPGYK-RVNNTFCQDINECQLQGVCPNGECLNTM 319
N+CQ+ P + H + C G++ V+ C+DINEC C EC N
Sbjct: 401 NECQRYPGRLCGHKCENTLGSYLCSCSVGFRLSVDGRSCEDINECS-SSPCSQ-ECANVY 458
Query: 320 GSYRCTCKIGF 330
GSY+C C+ G+
Sbjct: 459 GSYQCYCRRGY 469
Score = 34.3 bits (77), Expect = 0.86
Identities = 20/59 (33%), Positives = 31/59 (52%), Gaps = 5/59 (8%)
Query: 286 CLPGYKR--VNNTFCQDINECQLQ--GVCPNGECLNTMGSYRCTC-KIGFGPDPTFSSC 339
C GY+ V+ C+DI+EC L G + C+N GS++C+C G+ P +C
Sbjct: 465 CRRGYQLSDVDGVTCEDIDECALPTGGHICSYRCINIPGSFQCSCPSSGYRLAPNGRNC 523
>gi|34734062 fibulin 1 isoform C precursor [Homo sapiens]
Length = 683
Score = 256 bits (655), Expect = 8e-68
Identities = 151/377 (40%), Positives = 203/377 (53%), Gaps = 36/377 (9%)
Query: 601 CSQGRCENTEGSFLCICPAGFMASEEGTNCIDVDECLR-PDVCGEGH-CVNTVGAFRCE- 657
C Q +C +T +C C G+ +G +C DV+EC+ C G C+NTVG+FRC+
Sbjct: 186 CKQ-QCRDTGDEVVCSCFVGYQLLSDGVSCEDVNECITGSHSCRLGESCINTVGSFRCQR 244
Query: 658 --YCDSGYRMTQRGRCEDIDECLN--PSTCPDEQCVNSPGSYQCVP---CTEGF-RGWNG 709
C +GY +T+ C+DIDEC + + PD C N+ GS++C P C GF + G
Sbjct: 245 DSSCGTGYELTEDNSCKDIDECESGIHNCLPDFICQNTLGSFRCRPKLQCKSGFIQDALG 304
Query: 710 QCLDVDECLEPNV-CANG-DCSNLEGSYMC-----SCHKGYTRTPDHKHCRDIDEC-QQG 761
C+D++ECL + C G C N EGSY C +C +GY + C D+DEC
Sbjct: 305 NCIDINECLSISAPCPIGHTCINTEGSYTCQKNVPNCGRGYHLNEEGTRCVDVDECAPPA 364
Query: 762 NLCVNG-QCKNTEGSFRCTCGQGYQLSAAKDQCEDIDECQH--RHLCAHGQCRNTEGSFQ 818
C G +C N+ GSFRC C GY C D++ECQ LC H +C NT GS+
Sbjct: 365 EPCGKGHRCVNSPGSFRCECKTGYYFDGISRMCVDVNECQRYPGRLCGH-KCENTLGSYL 423
Query: 819 CVCDQGYRASGLGDHCEDINECLEDKSVCQRGDCINTAGSYDCTCPDGFQLD--DNKTCQ 876
C C G+R S G CEDINEC S C + +C N GSY C C G+QL D TC+
Sbjct: 424 CSCSVGFRLSVDGRSCEDINEC--SSSPCSQ-ECANVYGSYQCYCRRGYQLSDVDGVTCE 480
Query: 877 DINECEHP---GLCGPQGECLNTEGSFHCVC-QQGFSISADGRTCEDIDECVNNT-VCDS 931
DI+EC P +C + C+N GSF C C G+ ++ +GR C+DIDECV C
Sbjct: 481 DIDECALPTGGHICSYR--CINIPGSFQCSCPSSGYRLAPNGRNCQDIDECVTGIHNCSI 538
Query: 932 HGFCDNTAGSFRCLCYQ 948
+ C N G FRCL ++
Sbjct: 539 NETCFNIQGGFRCLAFE 555
Score = 226 bits (576), Expect = 1e-58
Identities = 158/429 (36%), Positives = 214/429 (49%), Gaps = 56/429 (13%)
Query: 545 QVTEINECTVNP---DICGAG-----HCINLPVRYTCICYEGYRFSEQQRKCVDIDECTQ 596
++ E+ E +P D C G C + C C+ GY+ C D++EC
Sbjct: 163 KIIEVEEEQEDPYLNDRCRGGGPCKQQCRDTGDEVVCSCFVGYQLLSDGVSCEDVNECIT 222
Query: 597 VQHLCSQGR-CENTEGSFLC----ICPAGFMASEEGTNCIDVDEC------LRPDVCGEG 645
H C G C NT GSF C C G+ +E+ +C D+DEC PD
Sbjct: 223 GSHSCRLGESCINTVGSFRCQRDSSCGTGYELTED-NSCKDIDECESGIHNCLPDFI--- 278
Query: 646 HCVNTVGAFRCE---YCDSGYRMTQRGRCEDIDECLNPST-CP-DEQCVNSPGSYQC--- 697
C NT+G+FRC C SG+ G C DI+ECL+ S CP C+N+ GSY C
Sbjct: 279 -CQNTLGSFRCRPKLQCKSGFIQDALGNCIDINECLSISAPCPIGHTCINTEGSYTCQKN 337
Query: 698 VP-CTEGF--RGWNGQCLDVDECLEP-NVCANGD-CSNLEGSYMCSCHKGYTRTPDHKHC 752
VP C G+ +C+DVDEC P C G C N GS+ C C GY + C
Sbjct: 338 VPNCGRGYHLNEEGTRCVDVDECAPPAEPCGKGHRCVNSPGSFRCECKTGYYFDGISRMC 397
Query: 753 RDIDECQQ--GNLCVNGQCKNTEGSFRCTCGQGYQLSAAKDQCEDIDECQHRHLCAHGQC 810
D++ECQ+ G LC +C+NT GS+ C+C G++LS CEDI+EC C+ +C
Sbjct: 398 VDVNECQRYPGRLC-GHKCENTLGSYLCSCSVGFRLSVDGRSCEDINECSSSP-CSQ-EC 454
Query: 811 RNTEGSFQCVCDQGYRASGL-GDHCEDINECL--EDKSVCQRGDCINTAGSYDCTCP-DG 866
N GS+QC C +GY+ S + G CEDI+EC +C CIN GS+ C+CP G
Sbjct: 455 ANVYGSYQCYCRRGYQLSDVDGVTCEDIDECALPTGGHICSY-RCINIPGSFQCSCPSSG 513
Query: 867 FQLDDN-KTCQDINECEHPGL--CGPQGECLNTEGSFHCV---CQQGFSISADGRTCEDI 920
++L N + CQDI+EC G+ C C N +G F C+ C + + SA R CE +
Sbjct: 514 YRLAPNGRNCQDIDECV-TGIHNCSINETCFNIQGGFRCLAFECPENYRRSAATR-CERL 571
Query: 921 DECVNNTVC 929
C N C
Sbjct: 572 -PCHENREC 579
Score = 168 bits (425), Expect = 4e-41
Identities = 173/630 (27%), Positives = 239/630 (37%), Gaps = 133/630 (21%)
Query: 565 INLPVRYTCICYEGYRFSEQQRKC-----VDIDECTQVQHLCSQGRCENTEGSFLCICPA 619
++ V C +G+R + Q+ C + EC VQ C + E C
Sbjct: 27 VDADVLLEACCADGHRMATHQKDCSLPYATESKECRMVQEQCCHSQLEELH------CAT 80
Query: 620 GFMASEEGTNCIDVDECLRPDVCGEGHCVNTVGAFRCEYCDSGYRMTQRGRCEDIDECLN 679
G + E D C P G+ + RC +C R Q
Sbjct: 81 GISLANEQ------DRCATPH--GDNASLEATFVKRCCHCCLLGRAAQA----------Q 122
Query: 680 PSTCPDEQCVNSPGSYQCVPCTEGFRGWNGQCLDVDECLEPNVCANGDCSNLEGSYMCSC 739
+C V YQC + FR C++ + D L+ +
Sbjct: 123 GQSCEYSLMVG----YQC---GQVFRAC---------CVKSQETGDLDVGGLQET----- 161
Query: 740 HKGYTRTPDHKHCRDIDECQQGNLCVNGQCKNTEGSFRCTCGQGYQLSAAKDQCEDIDEC 799
K + + D C+ G C QC++T C+C GYQL + CED++EC
Sbjct: 162 DKIIEVEEEQEDPYLNDRCRGGGPCKQ-QCRDTGDEVVCSCFVGYQLLSDGVSCEDVNEC 220
Query: 800 -QHRHLCAHGQ-CRNTEGSFQCV----CDQGYRASGLGDHCEDINECLEDKSVCQRGD-C 852
H C G+ C NT GSF+C C GY + + C+DI+EC C C
Sbjct: 221 ITGSHSCRLGESCINTVGSFRCQRDSSCGTGYELTE-DNSCKDIDECESGIHNCLPDFIC 279
Query: 853 INTAGSYDCT----CPDGFQLDDNKTCQDINECEHPGLCGPQGE-CLNTEGSFHCV---- 903
NT GS+ C C GF D C DINEC P G C+NTEGS+ C
Sbjct: 280 QNTLGSFRCRPKLQCKSGFIQDALGNCIDINECLSISAPCPIGHTCINTEGSYTCQKNVP 339
Query: 904 -CQQGFSISADGRTCEDIDECVNNTV-CDSHGFCDNTAGSFRCLCYQGFQAPQDGQGCVD 961
C +G+ ++ +G C D+DEC C C N+ GSFRC C G+ + CVD
Sbjct: 340 NCGRGYHLNEEGTRCVDVDECAPPAEPCGKGHRCVNSPGSFRCECKTGYYFDGISRMCVD 399
Query: 962 VNECELLSG-VCGEAFCENVEGSFLCVCADENQEYSPMTGQCRSRTSTDLDVDVDQPKEE 1020
VNEC+ G +CG CEN GS+LC C+ L VD + E+
Sbjct: 400 VNECQRYPGRLCGHK-CENTLGSYLCSCS----------------VGFRLSVD-GRSCED 441
Query: 1021 KKECYYNLNDASLCDNVLAPNVTKQECCCTSGAGWGDNCEIFPCPVLGTAEFTEMCPKGK 1080
EC +S C QEC G+ + C
Sbjct: 442 INEC-----SSSPC---------SQECANVYGS--------YQC---------------- 463
Query: 1081 GFVPAGESSSEAGGENYKDADECLL-FGQEICKNGFCLNTRPGYECYCKQGTY-YDPVKL 1138
+ G S+ G +D DEC L G IC C+N ++C C Y P
Sbjct: 464 -YCRRGYQLSDVDGVTCEDIDECALPTGGHICSYR-CINIPGSFQCSCPSSGYRLAPNGR 521
Query: 1139 QCFDMDECQD--PSSCIDGQCVNTEGSYNC 1166
C D+DEC + I+ C N +G + C
Sbjct: 522 NCQDIDECVTGIHNCSINETCFNIQGGFRC 551
Score = 148 bits (373), Expect = 4e-35
Identities = 84/234 (35%), Positives = 124/234 (52%), Gaps = 21/234 (8%)
Query: 544 TQVTEINECTVNPDICGAGH-CINLPVRYTCICYEGYRFSEQQRKCVDIDECTQVQHLCS 602
T+ +++EC + CG GH C+N P + C C GY F R CVD++EC +
Sbjct: 352 TRCVDVDECAPPAEPCGKGHRCVNSPGSFRCECKTGYYFDGISRMCVDVNECQRYPGRLC 411
Query: 603 QGRCENTEGSFLCICPAGFMASEEGTNCIDVDECLRPDVCGEGHCVNTVGAFRCEYCDSG 662
+CENT GS+LC C GF S +G +C D++EC C + C N G+++C YC G
Sbjct: 412 GHKCENTLGSYLCSCSVGFRLSVDGRSCEDINEC-SSSPCSQ-ECANVYGSYQC-YCRRG 468
Query: 663 YRMTQRG--RCEDIDECLNPS---TCPDEQCVNSPGSYQCVPCTEGFR-GWNGQ-CLDVD 715
Y+++ CEDIDEC P+ C +C+N PGS+QC + G+R NG+ C D+D
Sbjct: 469 YQLSDVDGVTCEDIDECALPTGGHIC-SYRCINIPGSFQCSCPSSGYRLAPNGRNCQDID 527
Query: 716 ECLE--PNVCANGDCSNLEGSYMC---SCHKGYTRTP----DHKHCRDIDECQQ 760
EC+ N N C N++G + C C + Y R+ + C + EC +
Sbjct: 528 ECVTGIHNCSINETCFNIQGGFRCLAFECPENYRRSAATRCERLPCHENRECSK 581
Score = 106 bits (265), Expect = 1e-22
Identities = 122/458 (26%), Positives = 176/458 (38%), Gaps = 77/458 (16%)
Query: 921 DECVNNTVCDSHGFCDNTAGSFRCLCYQGFQAPQDGQGCVDVNECELLSGVC--GEAFCE 978
D C C C +T C C+ G+Q DG C DVNEC S C GE+ C
Sbjct: 178 DRCRGGGPCKQQ--CRDTGDEVVCSCFVGYQLLSDGVSCEDVNECITGSHSCRLGES-CI 234
Query: 979 NVEGSFLCVCADENQEYSPMTGQCRSRTSTDLDVDVDQPKEEKKECYYNLNDASLCDNVL 1038
N GSF C ++ S TG + ++ D+D E + +N +C N L
Sbjct: 235 NTVGSFRC-----QRDSSCGTGYELTEDNSCKDID------ECESGIHNCLPDFICQNTL 283
Query: 1039 APNVTKQECCCTSGA---GWGDNCEI-------FPCPVLGTAEFTE---MCPKGKGFVPA 1085
+ + C SG G+ +I PCP+ T TE C K
Sbjct: 284 GSFRCRPKLQCKSGFIQDALGNCIDINECLSISAPCPIGHTCINTEGSYTCQKNVPNCGR 343
Query: 1086 GESSSEAGGENYKDADECLLFGQEICKNGFCLNTRPGYECYCKQGTYYDPVKLQCFDMDE 1145
G +E G D DEC + K C+N+ + C CK G Y+D + C D++E
Sbjct: 344 GYHLNEEG-TRCVDVDECAPPAEPCGKGHRCVNSPGSFRCECKTGYYFDGISRMCVDVNE 402
Query: 1146 CQD-PSSCIDGQCVNTEGSYNCFCTHPMVLDASEKRCIRPAESNEQIEETDVYQDLCWEH 1204
CQ P +C NT GSY C C+ L + C E I E
Sbjct: 403 CQRYPGRLCGHKCENTLGSYLCSCSVGFRLSVDGRSC-------EDINE----------- 444
Query: 1205 LSDEYVCSRPLVGKQTTYTECCCLYG----EAWGMQCALCPLKDSDDYAQLCNIPVTGRR 1260
CS+ +Y +C C G + G+ C +D D+ C +P G
Sbjct: 445 -CSSSPCSQECANVYGSY-QCYCRRGYQLSDVDGVTC-----EDIDE----CALPTGGHI 493
Query: 1261 QPYGRDALVDFSEQYTPEADPYFIQDRFLNSFEELQAEEC--GILNGCENGRCVRVQEGY 1318
Y R + S Q + + Y + N + +EC GI N N C +Q G+
Sbjct: 494 CSY-RCINIPGSFQCSCPSSGYRLAPNGRNCQD---IDECVTGIHNCSINETCFNIQGGF 549
Query: 1319 TC---DCFDGYHLDTA----KMTCVDVNECDELNNRMS 1349
C +C + Y A ++ C + EC +L R++
Sbjct: 550 RCLAFECPENYRRSAATRCERLPCHENRECSKLPLRIT 587
Score = 66.2 bits (160), Expect = 2e-10
Identities = 80/293 (27%), Positives = 107/293 (36%), Gaps = 63/293 (21%)
Query: 1116 CLNTRPGYECYCKQGTYYDPVKLQCFDMDECQDPS-SCIDGQ-CVNTEGSYNCFCTHPMV 1173
C +T C C G + C D++EC S SC G+ C+NT GS+ C
Sbjct: 190 CRDTGDEVVCSCFVGYQLLSDGVSCEDVNECITGSHSCRLGESCINTVGSFRC------- 242
Query: 1174 LDASEKRCIRPAESNEQIEETDVYQDLCWEHLSD---EYVCSRPLVGKQTTYTECCCLYG 1230
+ C E E D+ D C + + +++C L G + C G
Sbjct: 243 --QRDSSCGTGYELTEDNSCKDI--DECESGIHNCLPDFICQNTL-GSFRCRPKLQCKSG 297
Query: 1231 ---EAWGM-----QC----ALCPL-----KDSDDYAQLCNIPVTGRRQPYGRDAL--VDF 1271
+A G +C A CP+ Y N+P GR + VD
Sbjct: 298 FIQDALGNCIDINECLSISAPCPIGHTCINTEGSYTCQKNVPNCGRGYHLNEEGTRCVDV 357
Query: 1272 SEQYTPEADPYFIQDRFLNSFEELQAEECGILNGCENGRCVRVQEGYTCDCFDGYHLDTA 1331
E P AE CG + RCV + C+C GY+ D
Sbjct: 358 DECAPP-------------------AEPCG-----KGHRCVNSPGSFRCECKTGYYFDGI 393
Query: 1332 KMTCVDVNECDELNNRMSLCKNAKCINTDGSYKCLCLPGYVPSDKPNYCTPLN 1384
CVDVNEC R LC + KC NT GSY C C G+ S C +N
Sbjct: 394 SRMCVDVNECQRYPGR--LCGH-KCENTLGSYLCSCSVGFRLSVDGRSCEDIN 443
Score = 60.5 bits (145), Expect = 1e-08
Identities = 133/557 (23%), Positives = 182/557 (32%), Gaps = 173/557 (31%)
Query: 860 DCTCPDGFQLDDNKTCQDINECEHPGLCGPQGECLNTEGSFHCVCQQGFSISADGRTCED 919
DC+ P ++K C+ + E C Q E L+ C G S++ + C
Sbjct: 49 DCSLP---YATESKECRMVQE----QCCHSQLEELH--------CATGISLANEQDRC-- 91
Query: 920 IDECVNNTVCDSHGFCDNTAGSF--RCL--CYQGFQAPQDGQGCVDVNECELLSGV-CGE 974
HG + +F RC C G A GQ C E L+ G CG+
Sbjct: 92 ---------ATPHGDNASLEATFVKRCCHCCLLGRAAQAQGQSC----EYSLMVGYQCGQ 138
Query: 975 AFCENVEGSFLCVCADENQEYSPMTGQCRSRTSTDLDVDVDQPKEEKKECYYNLNDASLC 1034
F C ++QE TG DLDV Q ++ E D L
Sbjct: 139 VFR---------ACCVKSQE----TG--------DLDVGGLQETDKIIEVEEEQEDPYLN 177
Query: 1035 DNVLAPNVTKQECCCTSGAGWGDNCEIFPCPVLGTAEFTEMCPKGKGFVPAGESSSEAGG 1094
D KQ+C T GD E C G + G S
Sbjct: 178 DRCRGGGPCKQQCRDT-----GD-------------EVVCSCFVGYQLLSDGVSC----- 214
Query: 1095 ENYKDADECLLFGQEICKNG-FCLNTRPGYECYCKQ--GTYYDPVK-LQCFDMDECQDP- 1149
+D +EC+ G C+ G C+NT + C GT Y+ + C D+DEC+
Sbjct: 215 ---EDVNECIT-GSHSCRLGESCINTVGSFRCQRDSSCGTGYELTEDNSCKDIDECESGI 270
Query: 1150 SSCI-DGQCVNTEGSYNCF----CTHPMVLDASEKRCIRPAESNEQIEETDVYQDLCWEH 1204
+C+ D C NT GS+ C C + DA
Sbjct: 271 HNCLPDFICQNTLGSFRCRPKLQCKSGFIQDA---------------------------- 302
Query: 1205 LSDEYVCSRPLVGKQTTYTECCCLYGEAWGMQCALCPL-----KDSDDYAQLCNIPVTGR 1259
+G EC + A CP+ Y N+P GR
Sbjct: 303 -----------LGNCIDINECLSI--------SAPCPIGHTCINTEGSYTCQKNVPNCGR 343
Query: 1260 RQPYGRDAL--VDFSEQYTPEADPYFIQDRFLNSFEELQAE------------ECGILNG 1305
+ VD E P A+P R +NS + E C +N
Sbjct: 344 GYHLNEEGTRCVDVDE-CAPPAEPCGKGHRCVNSPGSFRCECKTGYYFDGISRMCVDVNE 402
Query: 1306 CEN-------GRCVRVQEGYTCDCFDGYHLDTAKMTCVDVNECDELNNRMSLCKNAKCIN 1358
C+ +C Y C C G+ L +C D+NEC S C +C N
Sbjct: 403 CQRYPGRLCGHKCENTLGSYLCSCSVGFRLSVDGRSCEDINECSS-----SPCSQ-ECAN 456
Query: 1359 TDGSYKCLCLPGYVPSD 1375
GSY+C C GY SD
Sbjct: 457 VYGSYQCYCRRGYQLSD 473
Score = 50.1 bits (118), Expect = 2e-05
Identities = 37/109 (33%), Positives = 45/109 (41%), Gaps = 13/109 (11%)
Query: 276 SYHGYNQMMECLPGYK-RVNNTFCQDINECQLQGV-CPNGE-CLNTMGSYRCTCKIGFGP 332
SY + C GY T C D++EC C G C+N+ GS+RC CK G+
Sbjct: 331 SYTCQKNVPNCGRGYHLNEEGTRCVDVDECAPPAEPCGKGHRCVNSPGSFRCECKTGYYF 390
Query: 333 DPTFSSCVPDPPVISEEKGPCYRLVSSGRQCMHPLSVHLTKQLCCCSVG 381
D CV + C R GR C H L LC CSVG
Sbjct: 391 DGISRMCV--------DVNECQRY--PGRLCGHKCENTLGSYLCSCSVG 429
Score = 43.5 bits (101), Expect = 0.001
Identities = 29/94 (30%), Positives = 43/94 (45%), Gaps = 23/94 (24%)
Query: 253 EDCCGTVGTSWGFNKCQKCPKKPSYHGYNQMMECLPGYKRVNNTFCQDINECQ--LQGVC 310
E C TVG+ +C + S C GY+ + C+DI+EC+ +
Sbjct: 231 ESCINTVGSF-------RCQRDSS---------CGTGYELTEDNSCKDIDECESGIHNCL 274
Query: 311 PNGECLNTMGSYRC----TCKIGFGPDPTFSSCV 340
P+ C NT+GS+RC CK GF D +C+
Sbjct: 275 PDFICQNTLGSFRCRPKLQCKSGFIQD-ALGNCI 307
Score = 42.4 bits (98), Expect = 0.003
Identities = 23/57 (40%), Positives = 29/57 (50%), Gaps = 2/57 (3%)
Query: 285 ECLPGYKRVN-NTFCQDINECQ-LQGVCPNGECLNTMGSYRCTCKIGFGPDPTFSSC 339
EC GY + C D+NECQ G +C NT+GSY C+C +GF SC
Sbjct: 383 ECKTGYYFDGISRMCVDVNECQRYPGRLCGHKCENTLGSYLCSCSVGFRLSVDGRSC 439
Score = 42.4 bits (98), Expect = 0.003
Identities = 24/71 (33%), Positives = 35/71 (49%), Gaps = 8/71 (11%)
Query: 266 NKCQKCPKKPSYHGYNQMM-----ECLPGYK-RVNNTFCQDINECQLQGVCPNGECLNTM 319
N+CQ+ P + H + C G++ V+ C+DINEC C EC N
Sbjct: 401 NECQRYPGRLCGHKCENTLGSYLCSCSVGFRLSVDGRSCEDINECS-SSPCSQ-ECANVY 458
Query: 320 GSYRCTCKIGF 330
GSY+C C+ G+
Sbjct: 459 GSYQCYCRRGY 469
Score = 34.3 bits (77), Expect = 0.86
Identities = 20/59 (33%), Positives = 31/59 (52%), Gaps = 5/59 (8%)
Query: 286 CLPGYKR--VNNTFCQDINECQLQ--GVCPNGECLNTMGSYRCTC-KIGFGPDPTFSSC 339
C GY+ V+ C+DI+EC L G + C+N GS++C+C G+ P +C
Sbjct: 465 CRRGYQLSDVDGVTCEDIDECALPTGGHICSYRCINIPGSFQCSCPSSGYRLAPNGRNC 523
>gi|51873055 fibulin 2 isoform b precursor [Homo sapiens]
Length = 1184
Score = 249 bits (635), Expect = 2e-65
Identities = 197/614 (32%), Positives = 280/614 (45%), Gaps = 87/614 (14%)
Query: 369 VHLTKQLC-CCSVG---KAWGPHCEKCPLPGTAAFKEICPGGMGYTVSGVHRRRPIHHHV 424
+ L KQ C CC +G +A G CE P +GY + V +
Sbjct: 512 ISLYKQCCDCCGLGLRVRAEGQSCESNP-------------NLGYPCNHVM----LSCCE 554
Query: 425 GKGPVFVKPKNTQPVAKSTHPPPLPAKEEPVEALTFSREHGPGVAEPEVATAPPEKEIPS 484
G+ P+ V P+ +P P P A EA RE E E+ + +P
Sbjct: 555 GEEPLIV-PEVRRP------PEPAAAPRRVSEAEMAGREALSLGTEAELPNS-----LPG 602
Query: 485 LDQEKTKLEPGQPQLSPGISTIHLH--PQFPGIVIEKTS--------PPVPVEVAPEAST 534
DQ++ L PG+ I+T+ + FPG ++ PP P A
Sbjct: 603 DDQDECLLLPGELCQHLCINTVGSYHCACFPGFSLQDDGRTCRPEGHPPQPEAPQEPALK 662
Query: 535 SSASQVIA---PTQVTEINECTVNPDICGAGHCINLPVRYTCICYEGYRFSEQQRKCVDI 591
S SQV + P + + N C N C + C C+ GY C DI
Sbjct: 663 SEFSQVASNTIPLPLPQPNTCKDNGPCKQV--CSTVGGSAICSCFPGYAIMADGVSCEDI 720
Query: 592 DECTQVQHLCSQGR-CENTEGSFLCI----CPAGFMASEEGTNCIDVDEC-LRPDVCGEG 645
+EC H CS+G C NT GSF C C G+ A ++G C DVDEC + C G
Sbjct: 721 NECVTDLHTCSRGEHCVNTLGSFHCYKALTCEPGY-ALKDG-ECEDVDECAMGTHTCQPG 778
Query: 646 H-CVNTVGAFRCEY---CDSGYRMTQRGRCEDIDEC--LNPSTCPDEQCVNSPGSYQC-- 697
C NT G+F C+ C G+ G C DI+EC L+ P C+N+ GSY C
Sbjct: 779 FLCQNTKGSFYCQARQRCMDGFLQDPEGNCVDINECTSLSEPCRPGFSCINTVGSYTCQR 838
Query: 698 --VPCTEGFRGWNG--QCLDVDECLEPNV--CANGD-CSNLEGSYMCSCHKGYTRTPDHK 750
+ C G+ + +C+DV+EC E V C G C NL GSY C C G+ R +
Sbjct: 839 NPLICARGYHASDDGTKCVDVNEC-ETGVHRCGEGQVCHNLPGSYRCDCKAGFQRDAFGR 897
Query: 751 HCRDIDEC--QQGNLCVNGQCKNTEGSFRCTCGQGYQLSAAKDQCEDIDECQHRHLCAHG 808
C D++EC G LC + C+NT GS+RC+C G+ L+A +CED++EC+ + C+
Sbjct: 898 GCIDVNECWASPGRLCQH-TCENTLGSYRCSCASGFLLAADGKRCEDVNECEAQR-CSQ- 954
Query: 809 QCRNTEGSFQCVCDQGYRASGLGDHCEDINECLEDKSVCQRGDCINTAGSYDCTCPD-GF 867
+C N GS+QC C QGY+ + G C DI+EC + + C+N GSY C CP+ G+
Sbjct: 955 ECANIYGSYQCYCRQGYQLAEDGHTCTDIDECAQGAGILCTFRCLNVPGSYQCACPEQGY 1014
Query: 868 QLDDN-KTCQDINECE-HPGLCGPQGECLNTEGSFHCV---CQQGF----SISADGRTCE 918
+ N ++C+D++EC C C N +GSF C+ C + + TC
Sbjct: 1015 TMTANGRSCKDVDECALGTHNCSEAETCHNIQGSFRCLRFECPPNYVQVSKTKCERTTCH 1074
Query: 919 DIDECVNNTVCDSH 932
D EC N+ +H
Sbjct: 1075 DFLECQNSPARITH 1088
Score = 217 bits (553), Expect = 5e-56
Identities = 157/481 (32%), Positives = 216/481 (44%), Gaps = 72/481 (14%)
Query: 590 DIDECTQVQHLCSQGRCENTEGSFLCICPAGFMASEEGTNCIDVDECLRPDVCGEGHCVN 649
D DEC + Q C NT GS+ C C GF ++G C +P+ E
Sbjct: 604 DQDECLLLPGELCQHLCINTVGSYHCACFPGFSLQDDGRTCRPEGHPPQPEAPQEP---- 659
Query: 650 TVGAFRCEYCDSGYR-----MTQRGRCEDIDECLNPSTCPDEQCVNSPGSYQCVPCTEGF 704
A + E+ + Q C+D C +Q ++ G C G+
Sbjct: 660 ---ALKSEFSQVASNTIPLPLPQPNTCKDNGPC--------KQVCSTVGGSAICSCFPGY 708
Query: 705 R--GWNGQCLDVDECL-EPNVCANGD-CSNLEGSYMC----SCHKGYTRTPDHKHCRDID 756
C D++EC+ + + C+ G+ C N GS+ C +C GY C D+D
Sbjct: 709 AIMADGVSCEDINECVTDLHTCSRGEHCVNTLGSFHCYKALTCEPGYALKDGE--CEDVD 766
Query: 757 ECQQG-NLCVNG-QCKNTEGSFRCT----CGQGYQLSAAKDQCEDIDECQH-RHLCAHG- 808
EC G + C G C+NT+GSF C C G+ L + C DI+EC C G
Sbjct: 767 ECAMGTHTCQPGFLCQNTKGSFYCQARQRCMDGF-LQDPEGNCVDINECTSLSEPCRPGF 825
Query: 809 QCRNTEGSFQC-----VCDQGYRASGLGDHCEDINECLEDKSVCQRGD-CINTAGSYDCT 862
C NT GS+ C +C +GY AS G C D+NEC C G C N GSY C
Sbjct: 826 SCINTVGSYTCQRNPLICARGYHASDDGTKCVDVNECETGVHRCGEGQVCHNLPGSYRCD 885
Query: 863 CPDGFQLDD-NKTCQDINEC-EHPG-LCGPQGECLNTEGSFHCVCQQGFSISADGRTCED 919
C GFQ D + C D+NEC PG LC Q C NT GS+ C C GF ++ADG+ CED
Sbjct: 886 CKAGFQRDAFGRGCIDVNECWASPGRLC--QHTCENTLGSYRCSCASGFLLAADGKRCED 943
Query: 920 IDECVNNTVCDSHGFCDNTAGSFRCLCYQGFQAPQDGQGCVDVNECELLSGVCGEAFCEN 979
++EC C N GS++C C QG+Q +DG C D++EC +G+ C N
Sbjct: 944 VNECEAQRCSQE---CANIYGSYQCYCRQGYQLAEDGHTCTDIDECAQGAGILCTFRCLN 1000
Query: 980 VEGSFLCVCADENQEYSPMTGQCRSRTSTDLDVDVDQPKEEKKEC---YYNLNDASLCDN 1036
V GS+ C C ++ + C+ DVD EC +N ++A C N
Sbjct: 1001 VPGSYQCACPEQGYTMTANGRSCK-------DVD---------ECALGTHNCSEAETCHN 1044
Query: 1037 V 1037
+
Sbjct: 1045 I 1045
Score = 142 bits (359), Expect = 2e-33
Identities = 190/748 (25%), Positives = 256/748 (34%), Gaps = 217/748 (29%)
Query: 708 NGQCLDVDEC-LEPNVCANGDCSNLEGSYMC--SCHKGYTRTPDHKHC--RDIDECQQGN 762
N +CL++ E E NVC + SY+ SC G + + C D D C
Sbjct: 456 NDECLEIPESGTEDNVCRTAQ-RHCCVSYLQEKSCMAGVLGAKEGETCGAEDNDSC---G 511
Query: 763 LCVNGQCKNTEGSFRCTCGQGYQLSAAKDQCEDIDECQHRHLCAHGQCRNTEGSFQCVCD 822
+ + QC + CG G ++ A CE + C H EG +
Sbjct: 512 ISLYKQCCDC-------CGLGLRVRAEGQSCESNPNLGYP--CNHVMLSCCEGEEPLIVP 562
Query: 823 Q--------------------GYRASGLGDHCE--------DINECLEDKSVCQRGDCIN 854
+ G A LG E D +ECL + CIN
Sbjct: 563 EVRRPPEPAAAPRRVSEAEMAGREALSLGTEAELPNSLPGDDQDECLLLPGELCQHLCIN 622
Query: 855 TAGSYDCTCPDGFQL-DDNKTCQ---------------------------------DINE 880
T GSY C C GF L DD +TC+ N
Sbjct: 623 TVGSYHCACFPGFSLQDDGRTCRPEGHPPQPEAPQEPALKSEFSQVASNTIPLPLPQPNT 682
Query: 881 CEHPGLCGPQGECLNTEGSFHCVCQQGFSISADGRTCEDIDECVNNT-VCDSHGFCDNTA 939
C+ G C + C GS C C G++I ADG +CEDI+ECV + C C NT
Sbjct: 683 CKDNGPC--KQVCSTVGGSAICSCFPGYAIMADGVSCEDINECVTDLHTCSRGEHCVNTL 740
Query: 940 GSFRCL----CYQGFQAPQDGQGCVDVNECELLSGVCGEAF-CENVEGSFLCVCADENQE 994
GSF C C G+ A +DG+ C DV+EC + + C F C+N +GSF C
Sbjct: 741 GSFHCYKALTCEPGY-ALKDGE-CEDVDECAMGTHTCQPGFLCQNTKGSFYC-------- 790
Query: 995 YSPMTGQCRSRTSTDLDVDVDQPKEEKKECYYNLNDASLCDNVLAPNVTKQECCCTSGAG 1054
Q R R +D + P+ N D + C ++ P C T G+
Sbjct: 791 ------QARQRC---MDGFLQDPEG-------NCVDINECTSLSEPCRPGFSCINTVGSY 834
Query: 1055 WGDNCEIFPCPVLGTAEFTEMCPKGKGFVPAGESSSEAGGENYKDADECLLFGQEICKNG 1114
C+ P +C +G + G D +EC G C G
Sbjct: 835 ---TCQRNPL----------ICARGY--------HASDDGTKCVDVNECET-GVHRCGEG 872
Query: 1115 FCLNTRPG-YECYCKQGTYYDPVKLQCFDMDEC-QDPSSCIDGQCVNTEGSYNCFCTHPM 1172
+ PG Y C CK G D C D++EC P C NT GSY C C
Sbjct: 873 QVCHNLPGSYRCDCKAGFQRDAFGRGCIDVNECWASPGRLCQHTCENTLGSYRCSCASGF 932
Query: 1173 VLDASEKRCIRPAESNEQIEETDVYQDLCWEHLSDEYVCSRPLVGKQTTYTECCCLYGEA 1232
+L A KRC E + E + + CS+ +Y +C C G
Sbjct: 933 LLAADGKRC-------EDVNECEAQR------------CSQECANIYGSY-QCYCRQGYQ 972
Query: 1233 WGMQCALCPLKDSDDYAQLCNIPVTGRRQPYGRDALVDFSEQYTPEADPYFIQDRFLNSF 1292
C D D+ AQ I T R
Sbjct: 973 LAEDGHTC--TDIDECAQGAGILCTFR--------------------------------- 997
Query: 1293 EELQAEECGILNGCENGRCVRVQEGYTCDCFD-GYHLDTAKMTCVDVNECDELNNRMSLC 1351
C+ V Y C C + GY + +C DV+EC + S
Sbjct: 998 ------------------CLNVPGSYQCACPEQGYTMTANGRSCKDVDECALGTHNCSEA 1039
Query: 1352 KNAKCINTDGSYKCL---CLPGYVPSDK 1376
+ C N GS++CL C P YV K
Sbjct: 1040 ET--CHNIQGSFRCLRFECPPNYVQVSK 1065
Score = 69.7 bits (169), Expect = 2e-11
Identities = 105/444 (23%), Positives = 158/444 (35%), Gaps = 83/444 (18%)
Query: 961 DVNECELLSGVCGEAFCENVEGSFLCVCADENQEYSPMTGQCRSRTSTDLDVDVDQPKEE 1020
D +EC LL G + C N GS+ C C + + Q RT + QP E
Sbjct: 604 DQDECLLLPGELCQHLCINTVGSYHCAC------FPGFSLQDDGRTCRP-EGHPPQP-EA 655
Query: 1021 KKECYYNLNDASLCDNVLAPNVTKQECCCTSGAGWGDNCEIFPCP-VLGTAEFTEMCPKG 1079
+E + + N + + + C +G PC V T + +C
Sbjct: 656 PQEPALKSEFSQVASNTIPLPLPQPNTCKDNG----------PCKQVCSTVGGSAICSCF 705
Query: 1080 KGFVPAGESSSEAGGENYKDADECLLFGQEICKNGFCLNTRPGYECY----CKQGTYYDP 1135
G+ + A G + +D +EC+ + C+NT + CY C+ G Y
Sbjct: 706 PGY------AIMADGVSCEDINECVTDLHTCSRGEHCVNTLGSFHCYKALTCEPG--YAL 757
Query: 1136 VKLQCFDMDEC-QDPSSCIDG-QCVNTEGSYNCFCTHPMV---LDASEKRCIRPAESNEQ 1190
+C D+DEC +C G C NT+GS+ C + L E C+
Sbjct: 758 KDGECEDVDECAMGTHTCQPGFLCQNTKGSFYCQARQRCMDGFLQDPEGNCV-------D 810
Query: 1191 IEETDVYQDLCWEHLS-----DEYVCSR-PLVGKQTTYTECCCLYGEAWGMQCALCPLKD 1244
I E + C S Y C R PL+ C G
Sbjct: 811 INECTSLSEPCRPGFSCINTVGSYTCQRNPLI----------CARG-----------YHA 849
Query: 1245 SDDYAQLCNIPV--TGRRQPYGRDALVDFSEQYTPEADPYFIQDRFLNSFEELQAEECGI 1302
SDD + ++ TG + + Y + F +D F + EC
Sbjct: 850 SDDGTKCVDVNECETGVHRCGEGQVCHNLPGSYRCDCKAGFQRDAFGRGC--IDVNECWA 907
Query: 1303 LNG--CENGRCVRVQEGYTCDCFDGYHLDTAKMTCVDVNECDELNNRMSLCKNAKCINTD 1360
G C++ C Y C C G+ L C DVNEC+ C +C N
Sbjct: 908 SPGRLCQH-TCENTLGSYRCSCASGFLLAADGKRCEDVNECEAQR-----CSQ-ECANIY 960
Query: 1361 GSYKCLCLPGYVPSDKPNYCTPLN 1384
GSY+C C GY ++ + CT ++
Sbjct: 961 GSYQCYCRQGYQLAEDGHTCTDID 984
Score = 69.3 bits (168), Expect = 2e-11
Identities = 123/583 (21%), Positives = 193/583 (33%), Gaps = 113/583 (19%)
Query: 854 NTAGSYDCTCPDGFQLDDNKTCQ--------DINECEHPGLCGPQGECLNTEGSFHCV-- 903
N+ S + P+G D +TC D +EC G + T CV
Sbjct: 424 NSVHSIPRSSPEGSTKDLIETCCAAGQQWAIDNDECLEIPESGTEDNVCRTAQRHCCVSY 483
Query: 904 -----CQQGFSISADGRTC--EDIDEC---VNNTVCDSHGFCDNTAGSFRCLCYQGFQAP 953
C G + +G TC ED D C + CD C G +
Sbjct: 484 LQEKSCMAGVLGAKEGETCGAEDNDSCGISLYKQCCDC--------------CGLGLRVR 529
Query: 954 QDGQGCVDVNECELLSGVCGEAFCENVEGSFLCVCADENQEYSP-----------MTGQC 1002
+GQ C L C EG + + + P M G+
Sbjct: 530 AEGQSCESNPN---LGYPCNHVMLSCCEGEEPLIVPEVRRPPEPAAAPRRVSEAEMAGRE 586
Query: 1003 RSRTSTDLDVDVDQPKEEKKECYYNLNDASLCDNVLAPNVTKQECCCTSGAGWGDNCEIF 1062
T+ ++ P +++ EC L LC ++ V C C G D+
Sbjct: 587 ALSLGTEAELPNSLPGDDQDECL--LLPGELCQHLCINTVGSYHCACFPGFSLQDD---- 640
Query: 1063 PCPVLGTAEFTEMC-PKGKGFVPAGESSSEAGGENYKDADECL---LFGQEICKNG---- 1114
C P+G P E + A + L CK+
Sbjct: 641 ----------GRTCRPEGHPPQPEAPQEPALKSEFSQVASNTIPLPLPQPNTCKDNGPCK 690
Query: 1115 -FCLNTRPGYECYCKQGTYYDPVKLQCFDMDEC-QDPSSCIDGQ-CVNTEGSYNCFCTHP 1171
C C C G + C D++EC D +C G+ CVNT GS++C+
Sbjct: 691 QVCSTVGGSAICSCFPGYAIMADGVSCEDINECVTDLHTCSRGEHCVNTLGSFHCY---- 746
Query: 1172 MVLDASEKRCIRPAESNEQIEETDVYQDLCWEHLSDEYVCSRPLVGKQTTYTECC--CLY 1229
L ++ E E ++E + C ++C K + Y + C+
Sbjct: 747 KALTCEPGYALKDGEC-EDVDECAMGTHTC----QPGFLCQNT---KGSFYCQARQRCMD 798
Query: 1230 GEAWGMQCALCPLKDSDDYAQLCNIPVTGRRQPYGRDALVDFSEQYTPEADPYFIQDRFL 1289
G + + + ++ C + ++ YT + +P +
Sbjct: 799 GFLQDPEGNCVDINECTSLSEPCRPGFS----------CINTVGSYTCQRNPLICARGYH 848
Query: 1290 NSFEELQAEECGILNGCENGR--------CVRVQEGYTCDCFDGYHLDTAKMTCVDVNEC 1341
S + +C +N CE G C + Y CDC G+ D C+DVNEC
Sbjct: 849 ASDD---GTKCVDVNECETGVHRCGEGQVCHNLPGSYRCDCKAGFQRDAFGRGCIDVNEC 905
Query: 1342 DELNNRMSLCKNAKCINTDGSYKCLCLPGYVPSDKPNYCTPLN 1384
R LC++ C NT GSY+C C G++ + C +N
Sbjct: 906 WASPGR--LCQHT-CENTLGSYRCSCASGFLLAADGKRCEDVN 945
Score = 55.8 bits (133), Expect = 3e-07
Identities = 50/150 (33%), Positives = 62/150 (41%), Gaps = 37/150 (24%)
Query: 247 PGLSKQEDCCGTVGTSWGFNKCQKCPKKPSYHGYNQMMECLPGYKRVNN-TFCQDINECQ 305
PG S C TVG+ CQ+ P + C GY ++ T C D+NEC+
Sbjct: 823 PGFS----CINTVGSY----TCQRNP-----------LICARGYHASDDGTKCVDVNECE 863
Query: 306 LQGV--CPNGE-CLNTMGSYRCTCKIGFGPDPTFSSCVPDPPVISEEKGPCYRLVSSGRQ 362
GV C G+ C N GSYRC CK GF D C+ + C+ S GR
Sbjct: 864 T-GVHRCGEGQVCHNLPGSYRCDCKAGFQRDAFGRGCI--------DVNECW--ASPGRL 912
Query: 363 CMHPLSVHLTKQLCCCSVG---KAWGPHCE 389
C H L C C+ G A G CE
Sbjct: 913 CQHTCENTLGSYRCSCASGFLLAADGKRCE 942
Score = 43.9 bits (102), Expect = 0.001
Identities = 25/67 (37%), Positives = 35/67 (52%), Gaps = 7/67 (10%)
Query: 271 CPKKPSYHGYNQMMECLPGYK-RVNNTFCQDINECQLQ-GVCPNGE-CLNTMGSYRC--- 324
C + S G + + C PGY + C+DINEC C GE C+NT+GS+ C
Sbjct: 689 CKQVCSTVGGSAICSCFPGYAIMADGVSCEDINECVTDLHTCSRGEHCVNTLGSFHCYKA 748
Query: 325 -TCKIGF 330
TC+ G+
Sbjct: 749 LTCEPGY 755
Score = 42.7 bits (99), Expect = 0.002
Identities = 37/119 (31%), Positives = 50/119 (42%), Gaps = 15/119 (12%)
Query: 237 TIGS-QCGKAL---PGLSKQEDCCGTVGT-SWGFNKCQK---CPKKPSYHGYNQMMECLP 288
T+GS C KAL PG + ++ C V + G + CQ C C+
Sbjct: 739 TLGSFHCYKALTCEPGYALKDGECEDVDECAMGTHTCQPGFLCQNTKGSFYCQARQRCMD 798
Query: 289 GYKRVNNTFCQDINEC-QLQGVC-PNGECLNTMGSYRC-----TCKIGFGPDPTFSSCV 340
G+ + C DINEC L C P C+NT+GSY C C G+ + CV
Sbjct: 799 GFLQDPEGNCVDINECTSLSEPCRPGFSCINTVGSYTCQRNPLICARGYHASDDGTKCV 857
Score = 39.3 bits (90), Expect = 0.027
Identities = 30/111 (27%), Positives = 48/111 (43%), Gaps = 18/111 (16%)
Query: 236 ETIGSQCGKA-----LPGLSKQEDCCGTVGTSWG-----FNKCQKCPKKPSYHGYNQMM- 284
ET +CG+ LPG + + G ++G N+C P + H +
Sbjct: 863 ETGVHRCGEGQVCHNLPGSYRCDCKAGFQRDAFGRGCIDVNECWASPGRLCQHTCENTLG 922
Query: 285 ----ECLPGYK-RVNNTFCQDINECQLQGVCPNGECLNTMGSYRCTCKIGF 330
C G+ + C+D+NEC+ Q + EC N GSY+C C+ G+
Sbjct: 923 SYRCSCASGFLLAADGKRCEDVNECEAQRC--SQECANIYGSYQCYCRQGY 971
Score = 37.4 bits (85), Expect = 0.10
Identities = 31/103 (30%), Positives = 45/103 (43%), Gaps = 21/103 (20%)
Query: 245 ALPGLSKQEDCCGTVGT-----SWGF------------NKC--QKCPKKPSYHGYNQMME 285
A PG Q C T+G+ + GF N+C Q+C ++ + +
Sbjct: 907 ASPGRLCQHTCENTLGSYRCSCASGFLLAADGKRCEDVNECEAQRCSQECANIYGSYQCY 966
Query: 286 CLPGYKRVNNTF-CQDINEC-QLQGVCPNGECLNTMGSYRCTC 326
C GY+ + C DI+EC Q G+ CLN GSY+C C
Sbjct: 967 CRQGYQLAEDGHTCTDIDECAQGAGILCTFRCLNVPGSYQCAC 1009
Score = 34.7 bits (78), Expect = 0.66
Identities = 31/109 (28%), Positives = 45/109 (41%), Gaps = 8/109 (7%)
Query: 300 DINECQL-QGVCPNGECLNTMGSYRCTCKIGFGPDPTFSSCVPD--PPVISEEKGPCYRL 356
D +EC L G C+NT+GSY C C GF +C P+ PP + P +
Sbjct: 604 DQDECLLLPGELCQHLCINTVGSYHCACFPGFSLQDDGRTCRPEGHPPQPEAPQEPALKS 663
Query: 357 VSSGRQCMHPLSVHLTKQLCCCSVGKAWGPHCEKCPLPGTAAFKEICPG 405
S + + + + L + C K GP + C G +A PG
Sbjct: 664 EFS-QVASNTIPLPLPQPNTC----KDNGPCKQVCSTVGGSAICSCFPG 707
>gi|62548862 matrilin 2 isoform b precursor [Homo sapiens]
Length = 937
Score = 238 bits (607), Expect = 3e-62
Identities = 143/444 (32%), Positives = 212/444 (47%), Gaps = 32/444 (7%)
Query: 538 SQVIAPTQVTEINECTVNPDICG------AGHCINLPVRYTCICYEGYRFSEQQRKCVDI 591
SQ+ T V + CT + +C A CIN+P Y C C +GY + Q C
Sbjct: 223 SQIETLTSVFQKKLCTAH--MCSTLEHNCAHFCINIPGSYVCRCKQGYILNSDQTTCRIQ 280
Query: 592 DECTQVQHLCSQGRCENTEGSFLCICPAGFMASEEGTNCIDVDECLRPDVCGEGHCVNTV 651
D C H C Q C N GSF+C C +G+ +E+G C+ VD C + E CVN
Sbjct: 281 DLCAMEDHNCEQ-LCVNVPGSFVCQCYSGYALAEDGKRCVAVDYCASENHGCEHECVNAD 339
Query: 652 GAFRCEYCDSGYRMT-QRGRCEDIDECLNPSTCPDEQCVNSPGSYQCVPCTEGFRGWNGQ 710
G++ C+ C G+ + + C ID C + + +CVN+ SY C C +GF
Sbjct: 340 GSYLCQ-CHEGFALNPDKKTCTKIDYCASSNHGCQHECVNTDDSYSC-HCLKGF------ 391
Query: 711 CLDVDE--CLEPNVCA------NGDCSNLEGSYMCSCHKGYTRTPDHKHCRDIDECQQGN 762
L+ D+ C N CA +C N+E SY C CH+GYT P+ K C +D C Q +
Sbjct: 392 TLNPDKKTCRRINYCALNKPGCEHECVNMEESYYCRCHRGYTLDPNGKTCSRVDHCAQQD 451
Query: 763 LCVNGQCKNTEGSFRCTCGQGYQLSAAKDQCEDIDEC-QHRHLCAHGQCRNTEGSFQCVC 821
C NTE SF C C +G+ ++ C +D C H C + C N + SF C C
Sbjct: 452 HGCEQLCLNTEDSFVCQCSEGFLINEDLKTCSRVDYCLLSDHGCEY-SCVNMDRSFACQC 510
Query: 822 DQGYRASGLGDHCEDINECLEDKSVCQRGDCINTAGSYDCTCPDGFQL-DDNKTCQDINE 880
+G+ G C ++ C C+ C+++ S+ C C +G+ L +D KTC+ +
Sbjct: 511 PEGHVLRSDGKTCAKLDSCALGDHGCEH-SCVSSEDSFVCQCFEGYILREDGKTCRRKDV 569
Query: 881 CEHPGLCGPQGECLNTEGSFHCVCQQGFSISADGRTCEDIDECVNNTVCDSHGFCDNTAG 940
C+ G + C+N++ S+ C C +GF ++ DG+ C D C +T C N
Sbjct: 570 CQAID-HGCEHICVNSDDSYTCECLEGFRLAEDGKRCRRKDVC-KSTHHGCEHICVNNGN 627
Query: 941 SFRCLCYQGFQAPQDGQGCVDVNE 964
S+ C C +GF +DG+ C E
Sbjct: 628 SYICKCSEGFVLAEDGRRCKKCTE 651
Score = 237 bits (605), Expect = 5e-62
Identities = 137/413 (33%), Positives = 199/413 (48%), Gaps = 17/413 (4%)
Query: 585 QRKCVDIDECTQVQHLCSQGRCENTEGSFLCICPAGFMASEEGTNCIDVDECLRPDVCGE 644
Q+K C+ ++H C+ C N GS++C C G++ + + T C D C D E
Sbjct: 233 QKKLCTAHMCSTLEHNCAHF-CINIPGSYVCRCKQGYILNSDQTTCRIQDLCAMEDHNCE 291
Query: 645 GHCVNTVGAFRCEYCDSGYRMTQRG-RCEDIDECLNPSTCPDEQCVNSPGSYQCVPCTEG 703
CVN G+F C+ C SGY + + G RC +D C + + + +CVN+ GSY C C EG
Sbjct: 292 QLCVNVPGSFVCQ-CYSGYALAEDGKRCVAVDYCASENHGCEHECVNADGSYLC-QCHEG 349
Query: 704 F--RGWNGQCLDVDECLEPNVCANGDCSNLEGSYMCSCHKGYTRTPDHKHCRDIDECQQG 761
F C +D C N +C N + SY C C KG+T PD K CR I+ C
Sbjct: 350 FALNPDKKTCTKIDYCASSNHGCQHECVNTDDSYSCHCLKGFTLNPDKKTCRRINYCALN 409
Query: 762 NLCVNGQCKNTEGSFRCTCGQGYQLSAAKDQCEDIDECQHRHLCAHGQCRNTEGSFQCVC 821
+C N E S+ C C +GY L C +D C + C NTE SF C C
Sbjct: 410 KPGCEHECVNMEESYYCRCHRGYTLDPNGKTCSRVDHCAQQDHGCEQLCLNTEDSFVCQC 469
Query: 822 DQGYRASGLGDHCEDINECLEDKSVCQRGDCINTAGSYDCTCPDGFQL-DDNKTCQDINE 880
+G+ + C ++ CL C+ C+N S+ C CP+G L D KTC ++
Sbjct: 470 SEGFLINEDLKTCSRVDYCLLSDHGCEYS-CVNMDRSFACQCPEGHVLRSDGKTCAKLDS 528
Query: 881 CEHPGLCGPQGECLNTEGSFHCVCQQGFSISADGRTCEDIDECVNNTVCDSHG---FCDN 937
C G G + C+++E SF C C +G+ + DG+TC D C HG C N
Sbjct: 529 CAL-GDHGCEHSCVSSEDSFVCQCFEGYILREDGKTCRRKDVCQ----AIDHGCEHICVN 583
Query: 938 TAGSFRCLCYQGFQAPQDGQGCVDVNECELLSGVCGEAFCENVEGSFLCVCAD 990
+ S+ C C +GF+ +DG+ C + C+ C E C N S++C C++
Sbjct: 584 SDDSYTCECLEGFRLAEDGKRCRRKDVCKSTHHGC-EHICVNNGNSYICKCSE 635
Score = 190 bits (482), Expect = 9e-48
Identities = 133/466 (28%), Positives = 193/466 (41%), Gaps = 74/466 (15%)
Query: 728 CSNLEGSYMCSCHKGYTRTPDHKHCRDIDECQQGNLCVNGQCKNTEGSFRCTCGQGYQLS 787
C N+ GSY+C C +GY D CR D C + C N GSF C C GY L+
Sbjct: 253 CINIPGSYVCRCKQGYILNSDQTTCRIQDLCAMEDHNCEQLCVNVPGSFVCQCYSGYALA 312
Query: 788 AAKDQCEDIDEC-QHRHLCAHGQCRNTEGSFQCVCDQGYRASGLGDHCEDINECLEDKSV 846
+C +D C H C H +C N +GS+ C C +G+ + C I+ C
Sbjct: 313 EDGKRCVAVDYCASENHGCEH-ECVNADGSYLCQCHEGFALNPDKKTCTKIDYCASSNHG 371
Query: 847 CQRGDCINTAGSYDCTCPDGFQLD-DNKTCQDINEC--EHPGLCGPQGECLNTEGSFHCV 903
CQ +C+NT SY C C GF L+ D KTC+ IN C PG + EC+N E S++C
Sbjct: 372 CQH-ECVNTDDSYSCHCLKGFTLNPDKKTCRRINYCALNKPGC---EHECVNMEESYYCR 427
Query: 904 CQQGFSISADGRTCEDIDECVNNTVCDSHG---FCDNTAGSFRCLCYQGFQAPQDGQGCV 960
C +G+++ +G+TC +D C HG C NT SF C C +GF +D + C
Sbjct: 428 CHRGYTLDPNGKTCSRVDHCAQQ----DHGCEQLCLNTEDSFVCQCSEGFLINEDLKTCS 483
Query: 961 DVNECELLSGVCGEAFCENVEGSFLCVCADENQEYSPMTGQCRSRTSTDLDVDVDQPKEE 1020
V+ C L C E C N++ SF C C
Sbjct: 484 RVDYCLLSDHGC-EYSCVNMDRSFACQCP------------------------------- 511
Query: 1021 KKECYYNLNDASLCDNVLAPNVTKQECCCTSGAGWGDNCEIFPCPVLGTAEFTEMCPKGK 1080
E + +D C K + C G +C ++E + +C +
Sbjct: 512 --EGHVLRSDGKTC--------AKLDSCALGDHGCEHSCV--------SSEDSFVCQCFE 553
Query: 1081 GFVPAGESSSEAGGENYKDADECLLFGQEICKNGFCLNTRPGYECYCKQGTYYDPVKLQC 1140
G++ + G+ + D C C++ C+N+ Y C C +G +C
Sbjct: 554 GYILRED------GKTCRRKDVCQAIDHG-CEH-ICVNSDDSYTCECLEGFRLAEDGKRC 605
Query: 1141 FDMDECQDPSSCIDGQCVNTEGSYNCFCTHPMVLDASEKRCIRPAE 1186
D C+ + CVN SY C C+ VL +RC + E
Sbjct: 606 RRKDVCKSTHHGCEHICVNNGNSYICKCSEGFVLAEDGRRCKKCTE 651
Score = 120 bits (300), Expect = 1e-26
Identities = 121/496 (24%), Positives = 183/496 (36%), Gaps = 110/496 (22%)
Query: 893 CLNTEGSFHCVCQQGFSISADGRTCEDIDEC-VNNTVCDSHGFCDNTAGSFRCLCYQGFQ 951
C+N GS+ C C+QG+ +++D TC D C + + C+ C N GSF C CY G+
Sbjct: 253 CINIPGSYVCRCKQGYILNSDQTTCRIQDLCAMEDHNCEQ--LCVNVPGSFVCQCYSGYA 310
Query: 952 APQDGQGCVDVNECELLSGVCGEAFCENVEGSFLCVCADENQEYSPMTGQCRSRTSTDLD 1011
+DG+ CV V+ C + C E C N +GS+LC C E +P
Sbjct: 311 LAEDGKRCVAVDYCASENHGC-EHECVNADGSYLCQC-HEGFALNP-------------- 354
Query: 1012 VDVDQPKEEKKECYYNLNDASLCDNVLAPNVTKQECCCTSGAGWGDNCEIFPCPVLGTAE 1071
+KK C TK + C +S G C V
Sbjct: 355 --------DKKTC------------------TKIDYCASSNHGCQHEC------VNTDDS 382
Query: 1072 FTEMCPKGKGFVPAGESSSEAGGENYKDADECLLFGQEICKNGFCLNTRPGYECYCKQGT 1131
++ C KG P ++ NY C L + C++ C+N Y C C +G
Sbjct: 383 YSCHCLKGFTLNPDKKTCRRI---NY-----CAL-NKPGCEHE-CVNMEESYYCRCHRGY 432
Query: 1132 YYDPVKLQCFDMDECQDPSSCIDGQCVNTEGSYNCFCTHPMVLDASEKRCIRPAESNEQI 1191
DP C +D C + C+NTE S+ C C+ +++ K C R
Sbjct: 433 TLDPNGKTCSRVDHCAQQDHGCEQLCLNTEDSFVCQCSEGFLINEDLKTCSR-------- 484
Query: 1192 EETDVYQDLCWEHLSDEYVCSRPLVGKQTTYTECCCLYGEAWGMQCALCPLKDSDDYAQL 1251
D C L ++ C V ++ C C G C DS
Sbjct: 485 ------VDYC---LLSDHGCEYSCVNMDRSFA-CQCPEGHVLRSDGKTCAKLDS------ 528
Query: 1252 CNIPVTGRRQPYGRDALVDFSEQYTPEADPYFIQDRFLNSFEELQAEEC-------GILN 1304
C + G E ++ F+ F + C I +
Sbjct: 529 CALGDHG-------------CEHSCVSSEDSFVCQCFEGYILREDGKTCRRKDVCQAIDH 575
Query: 1305 GCENGRCVRVQEGYTCDCFDGYHLDTAKMTCVDVNECDELNNRMSLCKNAKCINTDGSYK 1364
GCE+ CV + YTC+C +G+ L C + C ++ C++ C+N SY
Sbjct: 576 GCEH-ICVNSDDSYTCECLEGFRLAEDGKRCRRKDVCKSTHHG---CEHI-CVNNGNSYI 630
Query: 1365 CLCLPGYVPSDKPNYC 1380
C C G+V ++ C
Sbjct: 631 CKCSEGFVLAEDGRRC 646
Score = 74.7 bits (182), Expect = 6e-13
Identities = 71/277 (25%), Positives = 104/277 (37%), Gaps = 43/277 (15%)
Query: 1115 FCLNTRPGYECYCKQGTYYDPVKLQCFDMDECQDPSSCIDGQCVNTEGSYNCFCTHPMVL 1174
FC+N Y C CKQG + + C D C + CVN GS+ C C L
Sbjct: 252 FCINIPGSYVCRCKQGYILNSDQTTCRIQDLCAMEDHNCEQLCVNVPGSFVCQCYSGYAL 311
Query: 1175 DASEKRCIRPAESNEQIEETDVYQDLCWEHLSDEYVCSRPLVGKQTTYTECCCLYGEAWG 1234
KRC+ D C S+ + C V +Y C C G A
Sbjct: 312 AEDGKRCVAV--------------DYC---ASENHGCEHECVNADGSYL-CQCHEGFALN 353
Query: 1235 MQCALCPLKD---SDDYAQLCNIPVTGRRQPYGRDALVDFSEQYTPEADPYFIQDRFLNS 1291
C D S ++ C Y L F+ +P R +N
Sbjct: 354 PDKKTCTKIDYCASSNHG--CQHECVNTDDSYSCHCLKGFT------LNPDKKTCRRINY 405
Query: 1292 FEELQAEECGILN-GCENGRCVRVQEGYTCDCFDGYHLDTAKMTCVDVNECDELNNRMSL 1350
C + GCE+ CV ++E Y C C GY LD TC V+ C + ++
Sbjct: 406 --------CALNKPGCEH-ECVNMEESYYCRCHRGYTLDPNGKTCSRVDHCAQQDHG--- 453
Query: 1351 CKNAKCINTDGSYKCLCLPGYVPSDKPNYCTPLNTAL 1387
C+ C+NT+ S+ C C G++ ++ C+ ++ L
Sbjct: 454 CEQL-CLNTEDSFVCQCSEGFLINEDLKTCSRVDYCL 489
Score = 62.8 bits (151), Expect = 2e-09
Identities = 59/211 (27%), Positives = 89/211 (42%), Gaps = 37/211 (17%)
Query: 1190 QIEE-TDVYQD-LCWEHLSD--EYVCSRPLVGKQTTYTECCCLYGEAWGMQCALCPLKD- 1244
QIE T V+Q LC H+ E+ C+ + +Y C C G C ++D
Sbjct: 224 QIETLTSVFQKKLCTAHMCSTLEHNCAHFCINIPGSYV-CRCKQGYILNSDQTTCRIQDL 282
Query: 1245 ----SDDYAQLC-NIPVTGRRQPYGRDALVDFSEQYTPEADPYFIQDRFLNSFEELQAEE 1299
+ QLC N+P + Q Y AL + ++ + +
Sbjct: 283 CAMEDHNCEQLCVNVPGSFVCQCYSGYALAEDGKRC-------------------VAVDY 323
Query: 1300 CGILN-GCENGRCVRVQEGYTCDCFDGYHLDTAKMTCVDVNECDELNNRMSLCKNAKCIN 1358
C N GCE+ CV Y C C +G+ L+ K TC ++ C N+ C++ +C+N
Sbjct: 324 CASENHGCEH-ECVNADGSYLCQCHEGFALNPDKKTCTKIDYCASSNHG---CQH-ECVN 378
Query: 1359 TDGSYKCLCLPGYVPSDKPNYCTPLN-TALN 1388
TD SY C CL G+ + C +N ALN
Sbjct: 379 TDDSYSCHCLKGFTLNPDKKTCRRINYCALN 409
Score = 37.0 bits (84), Expect = 0.13
Identities = 29/114 (25%), Positives = 45/114 (39%), Gaps = 12/114 (10%)
Query: 285 ECLPGYKRVNN-TFCQDINECQLQGVCPNGECLNTMGSYRCTCKIGFGPDPTFSSCVPDP 343
+C GY + C ++ C + EC+N GSY C C GF +P +C
Sbjct: 304 QCYSGYALAEDGKRCVAVDYCASENHGCEHECVNADGSYLCQCHEGFALNPDKKTCTKID 363
Query: 344 PVISEEKGPCYRLV----SSGRQCMHPLSVHLTKQLC----CCSVGKAWGPHCE 389
S G + V S C+ +++ K+ C C++ K P CE
Sbjct: 364 YCASSNHGCQHECVNTDDSYSCHCLKGFTLNPDKKTCRRINYCALNK---PGCE 414
Score = 36.2 bits (82), Expect = 0.23
Identities = 19/55 (34%), Positives = 25/55 (45%), Gaps = 1/55 (1%)
Query: 286 CLPGYK-RVNNTFCQDINECQLQGVCPNGECLNTMGSYRCTCKIGFGPDPTFSSC 339
CL G+ + C+ IN C L EC+N SY C C G+ DP +C
Sbjct: 387 CLKGFTLNPDKKTCRRINYCALNKPGCEHECVNMEESYYCRCHRGYTLDPNGKTC 441
Score = 31.6 bits (70), Expect = 5.6
Identities = 25/98 (25%), Positives = 33/98 (33%), Gaps = 17/98 (17%)
Query: 300 DINECQLQGVCPNGE------CLNTMGSYRCTCKIGFGPDPTFSSCVPDPPVISEEKGPC 353
D C++Q +C + C+N GS+ C C G+ CV SE G
Sbjct: 273 DQTTCRIQDLCAMEDHNCEQLCVNVPGSFVCQCYSGYALAEDGKRCVAVDYCASENHG-- 330
Query: 354 YRLVSSGRQCMHPLSVHLTKQLCCCSVGKAWGPHCEKC 391
C H LC C G A P + C
Sbjct: 331 ---------CEHECVNADGSYLCQCHEGFALNPDKKTC 359
>gi|62548860 matrilin 2 isoform a precursor [Homo sapiens]
Length = 956
Score = 238 bits (607), Expect = 3e-62
Identities = 143/444 (32%), Positives = 212/444 (47%), Gaps = 32/444 (7%)
Query: 538 SQVIAPTQVTEINECTVNPDICG------AGHCINLPVRYTCICYEGYRFSEQQRKCVDI 591
SQ+ T V + CT + +C A CIN+P Y C C +GY + Q C
Sbjct: 223 SQIETLTSVFQKKLCTAH--MCSTLEHNCAHFCINIPGSYVCRCKQGYILNSDQTTCRIQ 280
Query: 592 DECTQVQHLCSQGRCENTEGSFLCICPAGFMASEEGTNCIDVDECLRPDVCGEGHCVNTV 651
D C H C Q C N GSF+C C +G+ +E+G C+ VD C + E CVN
Sbjct: 281 DLCAMEDHNCEQ-LCVNVPGSFVCQCYSGYALAEDGKRCVAVDYCASENHGCEHECVNAD 339
Query: 652 GAFRCEYCDSGYRMT-QRGRCEDIDECLNPSTCPDEQCVNSPGSYQCVPCTEGFRGWNGQ 710
G++ C+ C G+ + + C ID C + + +CVN+ SY C C +GF
Sbjct: 340 GSYLCQ-CHEGFALNPDKKTCTKIDYCASSNHGCQHECVNTDDSYSC-HCLKGF------ 391
Query: 711 CLDVDE--CLEPNVCA------NGDCSNLEGSYMCSCHKGYTRTPDHKHCRDIDECQQGN 762
L+ D+ C N CA +C N+E SY C CH+GYT P+ K C +D C Q +
Sbjct: 392 TLNPDKKTCRRINYCALNKPGCEHECVNMEESYYCRCHRGYTLDPNGKTCSRVDHCAQQD 451
Query: 763 LCVNGQCKNTEGSFRCTCGQGYQLSAAKDQCEDIDEC-QHRHLCAHGQCRNTEGSFQCVC 821
C NTE SF C C +G+ ++ C +D C H C + C N + SF C C
Sbjct: 452 HGCEQLCLNTEDSFVCQCSEGFLINEDLKTCSRVDYCLLSDHGCEY-SCVNMDRSFACQC 510
Query: 822 DQGYRASGLGDHCEDINECLEDKSVCQRGDCINTAGSYDCTCPDGFQL-DDNKTCQDINE 880
+G+ G C ++ C C+ C+++ S+ C C +G+ L +D KTC+ +
Sbjct: 511 PEGHVLRSDGKTCAKLDSCALGDHGCEH-SCVSSEDSFVCQCFEGYILREDGKTCRRKDV 569
Query: 881 CEHPGLCGPQGECLNTEGSFHCVCQQGFSISADGRTCEDIDECVNNTVCDSHGFCDNTAG 940
C+ G + C+N++ S+ C C +GF ++ DG+ C D C +T C N
Sbjct: 570 CQAID-HGCEHICVNSDDSYTCECLEGFRLAEDGKRCRRKDVC-KSTHHGCEHICVNNGN 627
Query: 941 SFRCLCYQGFQAPQDGQGCVDVNE 964
S+ C C +GF +DG+ C E
Sbjct: 628 SYICKCSEGFVLAEDGRRCKKCTE 651
Score = 237 bits (605), Expect = 5e-62
Identities = 137/413 (33%), Positives = 199/413 (48%), Gaps = 17/413 (4%)
Query: 585 QRKCVDIDECTQVQHLCSQGRCENTEGSFLCICPAGFMASEEGTNCIDVDECLRPDVCGE 644
Q+K C+ ++H C+ C N GS++C C G++ + + T C D C D E
Sbjct: 233 QKKLCTAHMCSTLEHNCAHF-CINIPGSYVCRCKQGYILNSDQTTCRIQDLCAMEDHNCE 291
Query: 645 GHCVNTVGAFRCEYCDSGYRMTQRG-RCEDIDECLNPSTCPDEQCVNSPGSYQCVPCTEG 703
CVN G+F C+ C SGY + + G RC +D C + + + +CVN+ GSY C C EG
Sbjct: 292 QLCVNVPGSFVCQ-CYSGYALAEDGKRCVAVDYCASENHGCEHECVNADGSYLC-QCHEG 349
Query: 704 F--RGWNGQCLDVDECLEPNVCANGDCSNLEGSYMCSCHKGYTRTPDHKHCRDIDECQQG 761
F C +D C N +C N + SY C C KG+T PD K CR I+ C
Sbjct: 350 FALNPDKKTCTKIDYCASSNHGCQHECVNTDDSYSCHCLKGFTLNPDKKTCRRINYCALN 409
Query: 762 NLCVNGQCKNTEGSFRCTCGQGYQLSAAKDQCEDIDECQHRHLCAHGQCRNTEGSFQCVC 821
+C N E S+ C C +GY L C +D C + C NTE SF C C
Sbjct: 410 KPGCEHECVNMEESYYCRCHRGYTLDPNGKTCSRVDHCAQQDHGCEQLCLNTEDSFVCQC 469
Query: 822 DQGYRASGLGDHCEDINECLEDKSVCQRGDCINTAGSYDCTCPDGFQL-DDNKTCQDINE 880
+G+ + C ++ CL C+ C+N S+ C CP+G L D KTC ++
Sbjct: 470 SEGFLINEDLKTCSRVDYCLLSDHGCEYS-CVNMDRSFACQCPEGHVLRSDGKTCAKLDS 528
Query: 881 CEHPGLCGPQGECLNTEGSFHCVCQQGFSISADGRTCEDIDECVNNTVCDSHG---FCDN 937
C G G + C+++E SF C C +G+ + DG+TC D C HG C N
Sbjct: 529 CAL-GDHGCEHSCVSSEDSFVCQCFEGYILREDGKTCRRKDVCQ----AIDHGCEHICVN 583
Query: 938 TAGSFRCLCYQGFQAPQDGQGCVDVNECELLSGVCGEAFCENVEGSFLCVCAD 990
+ S+ C C +GF+ +DG+ C + C+ C E C N S++C C++
Sbjct: 584 SDDSYTCECLEGFRLAEDGKRCRRKDVCKSTHHGC-EHICVNNGNSYICKCSE 635
Score = 190 bits (482), Expect = 9e-48
Identities = 133/466 (28%), Positives = 193/466 (41%), Gaps = 74/466 (15%)
Query: 728 CSNLEGSYMCSCHKGYTRTPDHKHCRDIDECQQGNLCVNGQCKNTEGSFRCTCGQGYQLS 787
C N+ GSY+C C +GY D CR D C + C N GSF C C GY L+
Sbjct: 253 CINIPGSYVCRCKQGYILNSDQTTCRIQDLCAMEDHNCEQLCVNVPGSFVCQCYSGYALA 312
Query: 788 AAKDQCEDIDEC-QHRHLCAHGQCRNTEGSFQCVCDQGYRASGLGDHCEDINECLEDKSV 846
+C +D C H C H +C N +GS+ C C +G+ + C I+ C
Sbjct: 313 EDGKRCVAVDYCASENHGCEH-ECVNADGSYLCQCHEGFALNPDKKTCTKIDYCASSNHG 371
Query: 847 CQRGDCINTAGSYDCTCPDGFQLD-DNKTCQDINEC--EHPGLCGPQGECLNTEGSFHCV 903
CQ +C+NT SY C C GF L+ D KTC+ IN C PG + EC+N E S++C
Sbjct: 372 CQH-ECVNTDDSYSCHCLKGFTLNPDKKTCRRINYCALNKPGC---EHECVNMEESYYCR 427
Query: 904 CQQGFSISADGRTCEDIDECVNNTVCDSHG---FCDNTAGSFRCLCYQGFQAPQDGQGCV 960
C +G+++ +G+TC +D C HG C NT SF C C +GF +D + C
Sbjct: 428 CHRGYTLDPNGKTCSRVDHCAQQ----DHGCEQLCLNTEDSFVCQCSEGFLINEDLKTCS 483
Query: 961 DVNECELLSGVCGEAFCENVEGSFLCVCADENQEYSPMTGQCRSRTSTDLDVDVDQPKEE 1020
V+ C L C E C N++ SF C C
Sbjct: 484 RVDYCLLSDHGC-EYSCVNMDRSFACQCP------------------------------- 511
Query: 1021 KKECYYNLNDASLCDNVLAPNVTKQECCCTSGAGWGDNCEIFPCPVLGTAEFTEMCPKGK 1080
E + +D C K + C G +C ++E + +C +
Sbjct: 512 --EGHVLRSDGKTC--------AKLDSCALGDHGCEHSCV--------SSEDSFVCQCFE 553
Query: 1081 GFVPAGESSSEAGGENYKDADECLLFGQEICKNGFCLNTRPGYECYCKQGTYYDPVKLQC 1140
G++ + G+ + D C C++ C+N+ Y C C +G +C
Sbjct: 554 GYILRED------GKTCRRKDVCQAIDHG-CEH-ICVNSDDSYTCECLEGFRLAEDGKRC 605
Query: 1141 FDMDECQDPSSCIDGQCVNTEGSYNCFCTHPMVLDASEKRCIRPAE 1186
D C+ + CVN SY C C+ VL +RC + E
Sbjct: 606 RRKDVCKSTHHGCEHICVNNGNSYICKCSEGFVLAEDGRRCKKCTE 651
Score = 120 bits (300), Expect = 1e-26
Identities = 121/496 (24%), Positives = 183/496 (36%), Gaps = 110/496 (22%)
Query: 893 CLNTEGSFHCVCQQGFSISADGRTCEDIDEC-VNNTVCDSHGFCDNTAGSFRCLCYQGFQ 951
C+N GS+ C C+QG+ +++D TC D C + + C+ C N GSF C CY G+
Sbjct: 253 CINIPGSYVCRCKQGYILNSDQTTCRIQDLCAMEDHNCEQ--LCVNVPGSFVCQCYSGYA 310
Query: 952 APQDGQGCVDVNECELLSGVCGEAFCENVEGSFLCVCADENQEYSPMTGQCRSRTSTDLD 1011
+DG+ CV V+ C + C E C N +GS+LC C E +P
Sbjct: 311 LAEDGKRCVAVDYCASENHGC-EHECVNADGSYLCQC-HEGFALNP-------------- 354
Query: 1012 VDVDQPKEEKKECYYNLNDASLCDNVLAPNVTKQECCCTSGAGWGDNCEIFPCPVLGTAE 1071
+KK C TK + C +S G C V
Sbjct: 355 --------DKKTC------------------TKIDYCASSNHGCQHEC------VNTDDS 382
Query: 1072 FTEMCPKGKGFVPAGESSSEAGGENYKDADECLLFGQEICKNGFCLNTRPGYECYCKQGT 1131
++ C KG P ++ NY C L + C++ C+N Y C C +G
Sbjct: 383 YSCHCLKGFTLNPDKKTCRRI---NY-----CAL-NKPGCEHE-CVNMEESYYCRCHRGY 432
Query: 1132 YYDPVKLQCFDMDECQDPSSCIDGQCVNTEGSYNCFCTHPMVLDASEKRCIRPAESNEQI 1191
DP C +D C + C+NTE S+ C C+ +++ K C R
Sbjct: 433 TLDPNGKTCSRVDHCAQQDHGCEQLCLNTEDSFVCQCSEGFLINEDLKTCSR-------- 484
Query: 1192 EETDVYQDLCWEHLSDEYVCSRPLVGKQTTYTECCCLYGEAWGMQCALCPLKDSDDYAQL 1251
D C L ++ C V ++ C C G C DS
Sbjct: 485 ------VDYC---LLSDHGCEYSCVNMDRSFA-CQCPEGHVLRSDGKTCAKLDS------ 528
Query: 1252 CNIPVTGRRQPYGRDALVDFSEQYTPEADPYFIQDRFLNSFEELQAEEC-------GILN 1304
C + G E ++ F+ F + C I +
Sbjct: 529 CALGDHG-------------CEHSCVSSEDSFVCQCFEGYILREDGKTCRRKDVCQAIDH 575
Query: 1305 GCENGRCVRVQEGYTCDCFDGYHLDTAKMTCVDVNECDELNNRMSLCKNAKCINTDGSYK 1364
GCE+ CV + YTC+C +G+ L C + C ++ C++ C+N SY
Sbjct: 576 GCEH-ICVNSDDSYTCECLEGFRLAEDGKRCRRKDVCKSTHHG---CEHI-CVNNGNSYI 630
Query: 1365 CLCLPGYVPSDKPNYC 1380
C C G+V ++ C
Sbjct: 631 CKCSEGFVLAEDGRRC 646
Score = 74.7 bits (182), Expect = 6e-13
Identities = 71/277 (25%), Positives = 104/277 (37%), Gaps = 43/277 (15%)
Query: 1115 FCLNTRPGYECYCKQGTYYDPVKLQCFDMDECQDPSSCIDGQCVNTEGSYNCFCTHPMVL 1174
FC+N Y C CKQG + + C D C + CVN GS+ C C L
Sbjct: 252 FCINIPGSYVCRCKQGYILNSDQTTCRIQDLCAMEDHNCEQLCVNVPGSFVCQCYSGYAL 311
Query: 1175 DASEKRCIRPAESNEQIEETDVYQDLCWEHLSDEYVCSRPLVGKQTTYTECCCLYGEAWG 1234
KRC+ D C S+ + C V +Y C C G A
Sbjct: 312 AEDGKRCVAV--------------DYC---ASENHGCEHECVNADGSYL-CQCHEGFALN 353
Query: 1235 MQCALCPLKD---SDDYAQLCNIPVTGRRQPYGRDALVDFSEQYTPEADPYFIQDRFLNS 1291
C D S ++ C Y L F+ +P R +N
Sbjct: 354 PDKKTCTKIDYCASSNHG--CQHECVNTDDSYSCHCLKGFT------LNPDKKTCRRINY 405
Query: 1292 FEELQAEECGILN-GCENGRCVRVQEGYTCDCFDGYHLDTAKMTCVDVNECDELNNRMSL 1350
C + GCE+ CV ++E Y C C GY LD TC V+ C + ++
Sbjct: 406 --------CALNKPGCEH-ECVNMEESYYCRCHRGYTLDPNGKTCSRVDHCAQQDHG--- 453
Query: 1351 CKNAKCINTDGSYKCLCLPGYVPSDKPNYCTPLNTAL 1387
C+ C+NT+ S+ C C G++ ++ C+ ++ L
Sbjct: 454 CEQL-CLNTEDSFVCQCSEGFLINEDLKTCSRVDYCL 489
Score = 62.8 bits (151), Expect = 2e-09
Identities = 59/211 (27%), Positives = 89/211 (42%), Gaps = 37/211 (17%)
Query: 1190 QIEE-TDVYQD-LCWEHLSD--EYVCSRPLVGKQTTYTECCCLYGEAWGMQCALCPLKD- 1244
QIE T V+Q LC H+ E+ C+ + +Y C C G C ++D
Sbjct: 224 QIETLTSVFQKKLCTAHMCSTLEHNCAHFCINIPGSYV-CRCKQGYILNSDQTTCRIQDL 282
Query: 1245 ----SDDYAQLC-NIPVTGRRQPYGRDALVDFSEQYTPEADPYFIQDRFLNSFEELQAEE 1299
+ QLC N+P + Q Y AL + ++ + +
Sbjct: 283 CAMEDHNCEQLCVNVPGSFVCQCYSGYALAEDGKRC-------------------VAVDY 323
Query: 1300 CGILN-GCENGRCVRVQEGYTCDCFDGYHLDTAKMTCVDVNECDELNNRMSLCKNAKCIN 1358
C N GCE+ CV Y C C +G+ L+ K TC ++ C N+ C++ +C+N
Sbjct: 324 CASENHGCEH-ECVNADGSYLCQCHEGFALNPDKKTCTKIDYCASSNHG---CQH-ECVN 378
Query: 1359 TDGSYKCLCLPGYVPSDKPNYCTPLN-TALN 1388
TD SY C CL G+ + C +N ALN
Sbjct: 379 TDDSYSCHCLKGFTLNPDKKTCRRINYCALN 409
Score = 37.0 bits (84), Expect = 0.13
Identities = 29/114 (25%), Positives = 45/114 (39%), Gaps = 12/114 (10%)
Query: 285 ECLPGYKRVNN-TFCQDINECQLQGVCPNGECLNTMGSYRCTCKIGFGPDPTFSSCVPDP 343
+C GY + C ++ C + EC+N GSY C C GF +P +C
Sbjct: 304 QCYSGYALAEDGKRCVAVDYCASENHGCEHECVNADGSYLCQCHEGFALNPDKKTCTKID 363
Query: 344 PVISEEKGPCYRLV----SSGRQCMHPLSVHLTKQLC----CCSVGKAWGPHCE 389
S G + V S C+ +++ K+ C C++ K P CE
Sbjct: 364 YCASSNHGCQHECVNTDDSYSCHCLKGFTLNPDKKTCRRINYCALNK---PGCE 414
Score = 36.2 bits (82), Expect = 0.23
Identities = 19/55 (34%), Positives = 25/55 (45%), Gaps = 1/55 (1%)
Query: 286 CLPGYK-RVNNTFCQDINECQLQGVCPNGECLNTMGSYRCTCKIGFGPDPTFSSC 339
CL G+ + C+ IN C L EC+N SY C C G+ DP +C
Sbjct: 387 CLKGFTLNPDKKTCRRINYCALNKPGCEHECVNMEESYYCRCHRGYTLDPNGKTC 441
Score = 31.6 bits (70), Expect = 5.6
Identities = 25/98 (25%), Positives = 33/98 (33%), Gaps = 17/98 (17%)
Query: 300 DINECQLQGVCPNGE------CLNTMGSYRCTCKIGFGPDPTFSSCVPDPPVISEEKGPC 353
D C++Q +C + C+N GS+ C C G+ CV SE G
Sbjct: 273 DQTTCRIQDLCAMEDHNCEQLCVNVPGSFVCQCYSGYALAEDGKRCVAVDYCASENHG-- 330
Query: 354 YRLVSSGRQCMHPLSVHLTKQLCCCSVGKAWGPHCEKC 391
C H LC C G A P + C
Sbjct: 331 ---------CEHECVNADGSYLCQCHEGFALNPDKKTC 359
>gi|118572606 hemicentin 1 [Homo sapiens]
Length = 5635
Score = 237 bits (605), Expect = 5e-62
Identities = 148/418 (35%), Positives = 206/418 (49%), Gaps = 57/418 (13%)
Query: 575 CYEGYRFSEQQRKCVDIDECTQVQHLCSQGRCENTEGSFLCICPAGFMASEEGTNCIDVD 634
C G+ C D DEC + CS C N G++ C CP G + +G C D+D
Sbjct: 5092 CPSGFTLDSVGPFCADEDECA-AGNPCSHS-CHNAMGTYYCSCPKGLTIAADGRTCQDID 5149
Query: 635 EC-LRPDVCGEGH-CVNTVGAFRCEY-CDSGYRMTQRG-RCEDIDECLNPSTCPDEQCVN 690
EC L C G C NT+G++RC C SG+R T G C+DI+EC S C ++C N
Sbjct: 5150 ECALGRHTCHAGQDCDNTIGSYRCVVRCGSGFRRTSDGLSCQDINECQESSPC-HQRCFN 5208
Query: 691 SPGSYQCVPCTEGFRGWNGQCLDVDECLEPNVCA-NGDCSNLEGSYMCS--CHKGYTRTP 747
+ GS+ C C G++ +C+DV+EC + NVC + C N G Y C C G T+
Sbjct: 5209 AIGSFHC-GCEPGYQLKGRKCMDVNECRQ-NVCRPDQHCKNTRGGYKCIDLCPNGMTKA- 5265
Query: 748 DHKHCRDIDECQQG-NLCVNGQ-CKNTEGSFRCTCGQGYQLSAAKDQCEDIDECQH-RHL 804
++ C DIDEC+ G + C Q C+NT GS+RC C +GY+ C DI+EC+
Sbjct: 5266 ENGTCIDIDECKDGTHQCRYNQICENTRGSYRCVCPRGYRSQGVGRPCMDINECEQVPKP 5325
Query: 805 CAHGQCRNTEGSFQCVCDQGYRASGLGDHCEDI----------------------NECLE 842
CAH QC NT GSF+C+C G G G C + N
Sbjct: 5326 CAH-QCSNTPGSFKCICPPGQHLLGDGKSCAGLERLPNYGTQYSSYNLARFSPVRNNYQP 5384
Query: 843 DKSVCQ--------------RGDCINTAGSYDCTCPDGFQLDDNKTCQDINECEHPGLCG 888
+ Q R T + TCP+G + + TC DI+ECE+ C
Sbjct: 5385 QQHYRQYSHLYSSYSEYRNSRTSLSRTRRTIRKTCPEGSEA-SHDTCVDIDECENTDAC- 5442
Query: 889 PQGECLNTEGSFHCVCQQGFSISADGRTCEDIDECVNNTV-CDSHGFCDNTAGSFRCL 945
Q EC NT GS+ C+C G+ ++ +G+TC+DIDEC+ V C + C N GS++C+
Sbjct: 5443 -QHECKNTFGSYQCICPPGYQLTHNGKTCQDIDECLEQNVHCGPNRMCFNMRGSYQCI 5499
Score = 235 bits (600), Expect = 2e-61
Identities = 155/437 (35%), Positives = 206/437 (47%), Gaps = 63/437 (14%)
Query: 617 CPAGFMASEEGTNCIDVDECLRPDVCGEGHCVNTVGAFRCEYCDSGYRMTQRGR-CEDID 675
CP+GF G C D DEC + C C N +G + C C G + GR C+DID
Sbjct: 5092 CPSGFTLDSVGPFCADEDECAAGNPCSHS-CHNAMGTYYCS-CPKGLTIAADGRTCQDID 5149
Query: 676 EC-LNPSTC-PDEQCVNSPGSYQCVP-CTEGFRGWNG--QCLDVDECLEPNVCANGDCSN 730
EC L TC + C N+ GSY+CV C GFR + C D++EC E + C + C N
Sbjct: 5150 ECALGRHTCHAGQDCDNTIGSYRCVVRCGSGFRRTSDGLSCQDINECQESSPC-HQRCFN 5208
Query: 731 LEGSYMCSCHKGYTRTPDHKHCRDIDECQQGNLCVNGQ-CKNTEGSFRCT--CGQGYQLS 787
GS+ C C GY + C D++EC+Q N+C Q CKNT G ++C C G
Sbjct: 5209 AIGSFHCGCEPGYQLKG--RKCMDVNECRQ-NVCRPDQHCKNTRGGYKCIDLCPNG-MTK 5264
Query: 788 AAKDQCEDIDECQH-RHLCAHGQ-CRNTEGSFQCVCDQGYRASGLGDHCEDINECLEDKS 845
A C DIDEC+ H C + Q C NT GS++CVC +GYR+ G+G C DINEC +
Sbjct: 5265 AENGTCIDIDECKDGTHQCRYNQICENTRGSYRCVCPRGYRSQGVGRPCMDINECEQVPK 5324
Query: 846 VCQRGDCINTAGSYDCTCPDGFQL-DDNKTCQDINECEHPG------------------- 885
C C NT GS+ C CP G L D K+C + + G
Sbjct: 5325 PCAH-QCSNTPGSFKCICPPGQHLLGDGKSCAGLERLPNYGTQYSSYNLARFSPVRNNYQ 5383
Query: 886 ----------LCGPQGECLN-------TEGSFHCVCQQGFSISADGRTCEDIDECVNNTV 928
L E N T + C +G S D TC DIDEC N
Sbjct: 5384 PQQHYRQYSHLYSSYSEYRNSRTSLSRTRRTIRKTCPEGSEASHD--TCVDIDECENTDA 5441
Query: 929 CDSHGFCDNTAGSFRCLCYQGFQAPQDGQGCVDVNECELLSGVCG-EAFCENVEGSFLCV 987
C C NT GS++C+C G+Q +G+ C D++EC + CG C N+ GS+ C+
Sbjct: 5442 CQHE--CKNTFGSYQCICPPGYQLTHNGKTCQDIDECLEQNVHCGPNRMCFNMRGSYQCI 5499
Query: 988 --CADENQEYSPMTGQC 1002
N + P++G C
Sbjct: 5500 DTPCPPNYQRDPVSGFC 5516
Score = 234 bits (597), Expect = 4e-61
Identities = 142/398 (35%), Positives = 195/398 (48%), Gaps = 58/398 (14%)
Query: 557 DICGAGH-----CINLPVRYTCICYEGYRFSEQQRKCVDIDECTQVQHLCSQGR-CENTE 610
D C AG+ C N Y C C +G + R C DIDEC +H C G+ C+NT
Sbjct: 5109 DECAAGNPCSHSCHNAMGTYYCSCPKGLTIAADGRTCQDIDECALGRHTCHAGQDCDNTI 5168
Query: 611 GSFLCI--CPAGFMASEEGTNCIDVDECLRPDVCGEGHCVNTVGAFRCEYCDSGYRMTQR 668
GS+ C+ C +GF + +G +C D++EC C + C N +G+F C C+ GY++ R
Sbjct: 5169 GSYRCVVRCGSGFRRTSDGLSCQDINECQESSPCHQ-RCFNAIGSFHCG-CEPGYQLKGR 5226
Query: 669 GRCEDIDECLNPSTCPDEQCVNSPGSYQCVP-CTEGF-RGWNGQCLDVDECLE-PNVCA- 724
+C D++EC PD+ C N+ G Y+C+ C G + NG C+D+DEC + + C
Sbjct: 5227 -KCMDVNECRQNVCRPDQHCKNTRGGYKCIDLCPNGMTKAENGTCIDIDECKDGTHQCRY 5285
Query: 725 NGDCSNLEGSYMCSCHKGYTRTPDHKHCRDIDECQQGNLCVNGQCKNTEGSFRCTCGQGY 784
N C N GSY C C +GY + C DI+EC+Q QC NT GSF+C C G
Sbjct: 5286 NQICENTRGSYRCVCPRGYRSQGVGRPCMDINECEQVPKPCAHQCSNTPGSFKCICPPGQ 5345
Query: 785 QLSAAKDQCEDIDEC-----------------------------QHRHL-CAHGQCRN-- 812
L C ++ Q+ HL ++ + RN
Sbjct: 5346 HLLGDGKSCAGLERLPNYGTQYSSYNLARFSPVRNNYQPQQHYRQYSHLYSSYSEYRNSR 5405
Query: 813 -----TEGSFQCVCDQGYRASGLGDHCEDINECLEDKSVCQRGDCINTAGSYDCTCPDGF 867
T + + C +G AS D C DI+EC E+ CQ +C NT GSY C CP G+
Sbjct: 5406 TSLSRTRRTIRKTCPEGSEAS--HDTCVDIDEC-ENTDACQH-ECKNTFGSYQCICPPGY 5461
Query: 868 QLDDN-KTCQDINEC-EHPGLCGPQGECLNTEGSFHCV 903
QL N KTCQDI+EC E CGP C N GS+ C+
Sbjct: 5462 QLTHNGKTCQDIDECLEQNVHCGPNRMCFNMRGSYQCI 5499
Score = 221 bits (564), Expect = 3e-57
Identities = 156/456 (34%), Positives = 207/456 (45%), Gaps = 48/456 (10%)
Query: 724 ANGDCSNLEGSYMCSCHKGYTRTPDHKHCRDIDECQQGNLCVNGQCKNTEGSFRCTCGQG 783
+ GD SN C G+T C D DEC GN C + C N G++ C+C +G
Sbjct: 5084 SKGDRSN-------QCPSGFTLDSVGPFCADEDECAAGNPC-SHSCHNAMGTYYCSCPKG 5135
Query: 784 YQLSAAKDQCEDIDECQ-HRHLCAHGQ-CRNTEGSFQCV--CDQGYRASGLGDHCEDINE 839
++A C+DIDEC RH C GQ C NT GS++CV C G+R + G C+DINE
Sbjct: 5136 LTIAADGRTCQDIDECALGRHTCHAGQDCDNTIGSYRCVVRCGSGFRRTSDGLSCQDINE 5195
Query: 840 CLEDKSVCQRGDCINTAGSYDCTCPDGFQLDDNKTCQDINECEHPGLCGPQGECLNTEGS 899
C E QR C N GS+ C C G+QL K C D+NEC +C P C NT G
Sbjct: 5196 CQESSPCHQR--CFNAIGSFHCGCEPGYQLKGRK-CMDVNECRQ-NVCRPDQHCKNTRGG 5251
Query: 900 FHCV--CQQGFSISADGRTCEDIDECVNNT-VCDSHGFCDNTAGSFRCLCYQGFQAPQDG 956
+ C+ C G + A+ TC DIDEC + T C + C+NT GS+RC+C +G+++ G
Sbjct: 5252 YKCIDLCPNGMT-KAENGTCIDIDECKDGTHQCRYNQICENTRGSYRCVCPRGYRSQGVG 5310
Query: 957 QGCVDVNECELLSGVCGEAFCENVEGSFLCVCADENQEYSPMTGQCRSRTSTDLDVDVDQ 1016
+ C+D+NECE + C C N GSF C+C + G +S +
Sbjct: 5311 RPCMDINECEQVPKPCAHQ-CSNTPGSFKCICPPGQH----LLGDGKSCAGLE-----RL 5360
Query: 1017 PKEEKKECYYNLNDASLCDNVLAPNV-TKQECCCTSGAGWGDNCEIFPCPVLGTAEFTEM 1075
P + YNL S N P +Q S N T T
Sbjct: 5361 PNYGTQYSSYNLARFSPVRNNYQPQQHYRQYSHLYSSYSEYRNSRTSLSRTRRTIRKT-- 5418
Query: 1076 CPKGKGFVPAGESSSEAGGENYKDADECLLFGQEICKNGFCLNTRPGYECYCKQGTYYDP 1135
CP+G SEA + D DEC + C++ C NT Y+C C G
Sbjct: 5419 CPEG----------SEASHDTCVDIDEC--ENTDACQHE-CKNTFGSYQCICPPGYQLTH 5465
Query: 1136 VKLQCFDMDEC--QDPSSCIDGQCVNTEGSYNCFCT 1169
C D+DEC Q+ + C N GSY C T
Sbjct: 5466 NGKTCQDIDECLEQNVHCGPNRMCFNMRGSYQCIDT 5501
Score = 140 bits (354), Expect = 7e-33
Identities = 104/323 (32%), Positives = 134/323 (41%), Gaps = 64/323 (19%)
Query: 863 CPDGFQLDD-NKTCQDINECEHPGLCGPQGECLNTEGSFHCVCQQGFSISADGRTCEDID 921
CP GF LD C D +EC C C N G+++C C +G +I+ADGRTC+DID
Sbjct: 5092 CPSGFTLDSVGPFCADEDECAAGNPCSHS--CHNAMGTYYCSCPKGLTIAADGRTCQDID 5149
Query: 922 EC-VNNTVCDSHGFCDNTAGSFRCL--CYQGFQAPQDGQGCVDVNECELLSGVCGEAFCE 978
EC + C + CDNT GS+RC+ C GF+ DG C D+NEC+ S C + C
Sbjct: 5150 ECALGRHTCHAGQDCDNTIGSYRCVVRCGSGFRRTSDGLSCQDINECQE-SSPCHQR-CF 5207
Query: 979 NVEGSFLCVCADENQEYSPMTGQCRSRTSTDLDVDVDQPKEEKKECYYNLNDASLCDNVL 1038
N GSF C C Q + R D++ EC NV
Sbjct: 5208 NAIGSFHCGCEPGYQ--------LKGRKCMDVN-----------ECR---------QNVC 5239
Query: 1039 APNVTKQECCCTSGAGWGDNCEIFPCPVLGTAEFTEMCPKGKGFVPAGESSSEAGGENYK 1098
P+ Q C T G G C ++CP G ++A
Sbjct: 5240 RPD---QHCKNTRG---GYKC-------------IDLCPNGM---------TKAENGTCI 5271
Query: 1099 DADECLLFGQEICKNGFCLNTRPGYECYCKQGTYYDPVKLQCFDMDECQDPSSCIDGQCV 1158
D DEC + N C NTR Y C C +G V C D++EC+ QC
Sbjct: 5272 DIDECKDGTHQCRYNQICENTRGSYRCVCPRGYRSQGVGRPCMDINECEQVPKPCAHQCS 5331
Query: 1159 NTEGSYNCFCTHPMVLDASEKRC 1181
NT GS+ C C L K C
Sbjct: 5332 NTPGSFKCICPPGQHLLGDGKSC 5354
Score = 86.3 bits (212), Expect = 2e-16
Identities = 117/482 (24%), Positives = 161/482 (33%), Gaps = 104/482 (21%)
Query: 946 CYQGFQAPQDGQGCVDVNECELLSGVCGEAFCENVEGSFLCVCADENQEYSPMTGQCRSR 1005
C GF G C D +EC C + C N G++ C C +T R
Sbjct: 5092 CPSGFTLDSVGPFCADEDECAA-GNPCSHS-CHNAMGTYYCSCP------KGLTIAADGR 5143
Query: 1006 TSTDLDVDVDQPKEEKKECY---YNLNDASLCDNVLAPNVTKQECCCTSGAGWGDNCEIF 1062
T D+D EC + + CDN + C G+G+ +
Sbjct: 5144 TCQDID-----------ECALGRHTCHAGQDCDNTIG----SYRCVVRCGSGFRRTSDGL 5188
Query: 1063 PCPVLGTAEFTEMCPKG-----KGFVPAGESSSEAGGENYKDADECLLFGQEICK-NGFC 1116
C + + + C + F E + G D +EC Q +C+ + C
Sbjct: 5189 SCQDINECQESSPCHQRCFNAIGSFHCGCEPGYQLKGRKCMDVNECR---QNVCRPDQHC 5245
Query: 1117 LNTRPGYECY--CKQGTYYDPVKLQCFDMDECQDPS-SCIDGQ-CVNTEGSYNCFCTHPM 1172
NTR GY+C C G C D+DEC+D + C Q C NT GSY C C
Sbjct: 5246 KNTRGGYKCIDLCPNGMT-KAENGTCIDIDECKDGTHQCRYNQICENTRGSYRCVCPRGY 5304
Query: 1173 VLDASEKRCIRPAESNEQIEETDVYQDLCWEHLSDEYVCSRPLVGKQTTYTECCCLYGEA 1232
+ C+ E EQ+ + +Q CS +C C G+
Sbjct: 5305 RSQGVGRPCMDINEC-EQVPKPCAHQ------------CSNT-----PGSFKCICPPGQH 5346
Query: 1233 WGMQCALCPLKDSDDYAQLCNIPVTGRRQPYGRDALVDFS---------EQYTPEADPYF 1283
L D A L +P G + Y L FS + Y + Y
Sbjct: 5347 L--------LGDGKSCAGLERLPNYGTQ--YSSYNLARFSPVRNNYQPQQHYRQYSHLYS 5396
Query: 1284 IQDRFLNSFEELQAEECGILNGCENGR------CVRVQE----------------GYTCD 1321
+ NS L I C G CV + E Y C
Sbjct: 5397 SYSEYRNSRTSLSRTRRTIRKTCPEGSEASHDTCVDIDECENTDACQHECKNTFGSYQCI 5456
Query: 1322 CFDGYHLDTAKMTCVDVNECDELNNRMSLCKNAKCINTDGSYKCL---CLPGYVPSDKPN 1378
C GY L TC D++EC E N + N C N GSY+C+ C P Y
Sbjct: 5457 CPPGYQLTHNGKTCQDIDECLEQN--VHCGPNRMCFNMRGSYQCIDTPCPPNYQRDPVSG 5514
Query: 1379 YC 1380
+C
Sbjct: 5515 FC 5516
Score = 52.8 bits (125), Expect = 2e-06
Identities = 64/269 (23%), Positives = 97/269 (36%), Gaps = 40/269 (14%)
Query: 1127 CKQGTYYDPVKLQCFDMDECQDPSSCIDGQCVNTEGSYNCFCTHPMVLDASEKRCIRPAE 1186
C G D V C D DEC + C C N G+Y C C + + A + C
Sbjct: 5092 CPSGFTLDSVGPFCADEDECAAGNPC-SHSCHNAMGTYYCSCPKGLTIAADGRTC----- 5145
Query: 1187 SNEQIEETDVYQDLCWEHLSDEYVCSRPLVGKQTTYTECCCLYGEAW-GMQCA-LCPLKD 1244
+ I+E + + C H + C +G C + G+ C + ++
Sbjct: 5146 --QDIDECALGRHTC--HAGQD--CDNT-IGSYRCVVRCGSGFRRTSDGLSCQDINECQE 5198
Query: 1245 SDDYAQLCNIPVTGRRQPYGRDALVDFSEQYTPEADPYFIQDRFLNSFEELQAEECGILN 1304
S Q C +A+ F P Y ++ R E + C
Sbjct: 5199 SSPCHQRCF------------NAIGSFHCGCEPG---YQLKGRKCMDVNECRQNVCRPDQ 5243
Query: 1305 GCENGRCVRVQEGYTC-DCFDGYHLDTAKMTCVDVNECDELNNRMSLCK-NAKCINTDGS 1362
C+N R GY C D TC+D++EC + ++ C+ N C NT GS
Sbjct: 5244 HCKNTR-----GGYKCIDLCPNGMTKAENGTCIDIDECKDGTHQ---CRYNQICENTRGS 5295
Query: 1363 YKCLCLPGYVPSDKPNYCTPLNTALNLEK 1391
Y+C+C GY C +N + K
Sbjct: 5296 YRCVCPRGYRSQGVGRPCMDINECEQVPK 5324
Score = 49.3 bits (116), Expect = 3e-05
Identities = 47/166 (28%), Positives = 68/166 (40%), Gaps = 20/166 (12%)
Query: 191 GQSQVSYQGLPVQKTQTIHSTYSHQQVIPHVYPVAA-----KTQLGRCFQETIGSQCGKA 245
G SY + + H + H+Y + +T L R + TI C +
Sbjct: 5364 GTQYSSYNLARFSPVRNNYQPQQHYRQYSHLYSSYSEYRNSRTSLSRT-RRTIRKTCPE- 5421
Query: 246 LPGLSKQEDCCGTVGTSWGFNKCQ-KCPKKPSYHGYNQMMECLPGYKRVNN-TFCQDINE 303
G D C + + CQ +C K ++ Y + C PGY+ +N CQDI+E
Sbjct: 5422 --GSEASHDTCVDIDECENTDACQHEC--KNTFGSYQCI--CPPGYQLTHNGKTCQDIDE 5475
Query: 304 CQLQGV-C-PNGECLNTMGSYRC---TCKIGFGPDPTFSSCVPDPP 344
C Q V C PN C N GSY+C C + DP C+ + P
Sbjct: 5476 CLEQNVHCGPNRMCFNMRGSYQCIDTPCPPNYQRDPVSGFCLKNCP 5521
Score = 47.4 bits (111), Expect = 1e-04
Identities = 54/198 (27%), Positives = 67/198 (33%), Gaps = 56/198 (28%)
Query: 232 RCFQETIGSQCGKALPGLSKQEDCCGTVGTSWGFNKCQKCPKKPSYH------GYNQMME 285
RCF CG PG + C V N+C++ +P H GY +
Sbjct: 5205 RCFNAIGSFHCG-CEPGYQLKGRKCMDV------NECRQNVCRPDQHCKNTRGGYKCIDL 5257
Query: 286 CLPGYKRVNNTFCQDINECQ--LQGVCPNGECLNTMGSYRCTCKIGFGPDPTFSSCVPDP 343
C G + N C DI+EC+ N C NT GSYRC C G
Sbjct: 5258 CPNGMTKAENGTCIDIDECKDGTHQCRYNQICENTRGSYRCVCPRG-------------- 5303
Query: 344 PVISEEKGPCYRLVSSGRQCMHPLSVHLTKQLCCCSVGKAWGPHCEKCPLPGTAAFKEIC 403
YR GR CM C V K C P +FK IC
Sbjct: 5304 ----------YRSQGVGRPCMDINE--------CEQVPKPCAHQCSNTP----GSFKCIC 5341
Query: 404 PGGM-----GYTVSGVHR 416
P G G + +G+ R
Sbjct: 5342 PPGQHLLGDGKSCAGLER 5359
Score = 40.8 bits (94), Expect = 0.009
Identities = 38/134 (28%), Positives = 54/134 (40%), Gaps = 28/134 (20%)
Query: 298 CQDINECQL-QGVCPNGE-CLNTMGSYRCTCKIGFGPDPTFSSCVPDPPVISEEKGPCYR 355
CQDI+EC L + C G+ C NT+GSYRC + G G T +E PC++
Sbjct: 5145 CQDIDECALGRHTCHAGQDCDNTIGSYRCVVRCGSGFRRTSDGLSCQDINECQESSPCHQ 5204
Query: 356 LVSS----------------GRQCMHPLSVHLTKQLCCCSVGKAWGPHCEKCPLPGTAAF 399
+ GR+CM V+ +Q C HC+ G
Sbjct: 5205 RCFNAIGSFHCGCEPGYQLKGRKCM---DVNECRQNVCRP-----DQHCKN--TRGGYKC 5254
Query: 400 KEICPGGMGYTVSG 413
++CP GM +G
Sbjct: 5255 IDLCPNGMTKAENG 5268
Score = 32.7 bits (73), Expect = 2.5
Identities = 14/33 (42%), Positives = 18/33 (54%), Gaps = 1/33 (3%)
Query: 297 FCQDINECQLQGVCPNGECLNTMGSYRCTCKIG 329
FC D +EC C + C N MG+Y C+C G
Sbjct: 5104 FCADEDECAAGNPCSHS-CHNAMGTYYCSCPKG 5135
>gi|24041035 notch 2 preproprotein [Homo sapiens]
Length = 2471
Score = 229 bits (585), Expect = 1e-59
Identities = 242/885 (27%), Positives = 356/885 (40%), Gaps = 183/885 (20%)
Query: 548 EINECTVNPDICGAGHCINLPVRYTCICYEGYRFSEQQRKCVDIDECTQVQHLCSQGRCE 607
EINEC NP + G C++ R+ C+C G+ Q +DID+C+ L + +C
Sbjct: 494 EINECQSNPCV-NNGQCVDKVNRFQCLCPPGFTGPVCQ---IDIDDCSSTPCL-NGAKCI 548
Query: 608 NTEGSFLCICPAGFMASEEGTNCID-VDECLRPDVCGEGHCVNTVGAFRCEYCDSGYRMT 666
+ + C C GF G C + +D C PD C G C + + ++ C C+ GY
Sbjct: 549 DHPNGYECQCATGFT----GVLCEENIDNC-DPDPCHHGQCQDGIDSYTC-ICNPGY--- 599
Query: 667 QRGRCED-IDECLNPSTCPDEQCVNSPGSYQCVPCTEGFRGWNGQCLDVDECLEPNVCAN 725
C D IDEC + D +C++ YQC C G G N + ++ D+C N C +
Sbjct: 600 MGAICSDQIDECYSSPCLNDGRCIDLVNGYQC-NCQPGTSGVNCE-INFDDCAS-NPCIH 656
Query: 726 GDCSNLEGSYMCSCHKGYTRTPDHKHCR-DIDECQQGNLCVNGQCKNTEGSFRCTCGQGY 784
G C + Y C C G+T + C DIDEC C N FRC C +G
Sbjct: 657 GICMDGINRYSCVCSPGFTG----QRCNIDIDECASNPCRKGATCINGVNGFRCICPEGP 712
Query: 785 QLSAAKDQCEDIDECQHRHLCAHGQCRNTEGSFQCVCDQGYRASGLGDHCE-DINECLED 843
+ Q ++EC C HG C ++C+CD G+ +G +CE D NECL +
Sbjct: 713 HHPSCYSQ---VNECLSNP-CIHGNCTGGLSGYKCLCDAGW----VGINCEVDKNECLSN 764
Query: 844 KSVCQRGD-CINTAGSYDCTCPDGFQLDDNKTCQ-DINECEHPGLCGPQGECLNTEGSFH 901
CQ G C N Y CTC GF+ CQ +I+EC C QG C + +
Sbjct: 765 P--CQNGGTCDNLVNGYRCTCKKGFK---GYNCQVNIDECAS-NPCLNQGTCFDDISGYT 818
Query: 902 CVCQQGFSISADGRTCEDIDECVNNTVCDSHGFCDNTAG--SFRCLCYQGFQAPQDGQGC 959
C C ++ G+ C+ + + C++ C + S+ CLC G+Q GQ C
Sbjct: 819 CHCVLPYT----GKNCQTVLAPCSPNPCENAAVCKESPNFESYTCLCAPGWQ----GQRC 870
Query: 960 -VDVNECELLSGVC-GEAFCENVEGSFLCVCADENQEYSPMTGQCRSRTSTDLDVDVDQP 1017
+D++EC +S C C N +GS++C C +S M D + D+D
Sbjct: 871 TIDIDEC--ISKPCMNHGLCHNTQGSYMCECPPG---FSGM----------DCEEDID-- 913
Query: 1018 KEEKKECYYNLNDASLCDNVLAPNVTKQECCCTSGAGWGDNCEIFPCPVLGTAEFTEMCP 1077
+C N C +G D F C L
Sbjct: 914 -----DCLANP--------------------CQNGGSCMDGVNTFSCLCL---------- 938
Query: 1078 KGKGFVPAGESSSEAGGENYKDADECLLFGQEICKNG-FCLNTRPGYECYCKQGTYYDPV 1136
GF G + D +ECL E CKNG C + Y C C+ G +D V
Sbjct: 939 --PGFT---------GDKCQTDMNECL---SEPCKNGGTCSDYVNSYTCKCQAG--FDGV 982
Query: 1137 KLQCFDMDECQDPSSCIDGQCVNTEGSYNCFCTHPMVLDASEKRCIRPAESNEQIEETDV 1196
+ +++EC + S G CV+ S++C C P+ S C+ E NE +
Sbjct: 983 HCEN-NINECTESSCFNGGTCVDGINSFSCLC--PVGFTGSF--CLH--EINECSSHPCL 1035
Query: 1197 YQDLCWEHLSDEYVCSRPL--VGK--QTTYTECC---------CLYGEAWGMQCALCPLK 1243
+ C + L Y CS PL GK QT C C+ +A QC LCP
Sbjct: 1036 NEGTCVDGLGT-YRCSCPLGYTGKNCQTLVNLCSRSPCKNKGTCVQKKAES-QC-LCPSG 1092
Query: 1244 DSDDYAQLCNIP--VTGRRQPYGRDALVDFSEQYTPEADPYFIQDR--FLNSFEELQAEE 1299
+ Y + N+ + R+ + L S + ++ Q + S+ E Q +E
Sbjct: 1093 WAGAYCDVPNVSCDIAASRRGVLVEHLCQHSGVCINAGNTHYCQCPLGYTGSYCEEQLDE 1152
Query: 1300 CGILNGCENGR-CVRVQEGYTCDCFDGYHL--------DTAKMTCVDVNECDELNNRMS- 1349
C N C++G C GY C+C GY + C + C +L N
Sbjct: 1153 CAS-NPCQHGATCSDFIGGYRCECVPGYQGVNCEYEVDECQNQPCQNGGTCIDLVNHFKC 1211
Query: 1350 ---------LCKN--------------AKCINTDGSYKCLCLPGY 1371
LC+ +C++ G Y C CLPG+
Sbjct: 1212 SCPPGTRGLLCEENIDDCARGPHCLNGGQCMDRIGGYSCRCLPGF 1256
Score = 228 bits (582), Expect = 2e-59
Identities = 237/866 (27%), Positives = 348/866 (40%), Gaps = 146/866 (16%)
Query: 547 TEINECTVNPDICGAGHCINLPVRYTCICYEGYRFSEQQRKCVDIDECTQVQHLCSQGRC 606
T++NEC + G C+NLP Y C C +G+ + C + + G C
Sbjct: 181 TDVNECDIPGHCQHGGTCLNLPGSYQCQCPQGF----TGQYCDSLYVPCAPSPCVNGGTC 236
Query: 607 ENT-EGSFLCICPAGFMASEEGTNC-IDVDECLRPDVCGEGHCVNTVGAFRCEYCDSGYR 664
T + +F C C GF EG+ C ++D+C G CV+ V + C C +
Sbjct: 237 RQTGDFTFECNCLPGF----EGSTCERNIDDCPNHRCQNGGVCVDGVNTYNCR-CPP--Q 289
Query: 665 MTQRGRCEDIDEC-LNPSTCPD-EQCVNSPGSYQCVPCTEGFRGWNGQCLD-VDECLEPN 721
T + ED+DEC L P+ C + C N G Y CV C G+ G C + +D+C +
Sbjct: 290 WTGQFCTEDVDECLLQPNACQNGGTCANRNGGYGCV-CVNGWSG--DDCSENIDDCAFAS 346
Query: 722 VCANGDCSNLEGSYMCSCHKGYTRTPDHKHCRDI-DECQQGNLCVNGQCKNTEGSFRCTC 780
C + S+ C C +G H I + C +G LC G + CTC
Sbjct: 347 CTPGSTCIDRVASFSCMCPEGKAGLLCHLDDACISNPCHKGALC---DTNPLNGQYICTC 403
Query: 781 GQGYQLSAAKDQCEDIDEC--QHRHLCAH-GQCRNTEGSFQCVCDQGYRASGLGDHCE-D 836
QGY+ D ED+DEC + + C H G+C NT+G+F C C +GY G CE D
Sbjct: 404 PQGYK---GADCTEDVDECAMANSNPCEHAGKCVNTDGAFHCECLKGY----AGPRCEMD 456
Query: 837 INECLEDKSVCQR-GDCINTAGSYDCTCPDGFQLDDNKTCQ-DINECEHPGLCGPQGECL 894
INEC D CQ C++ G + C C GF+ C+ +INEC+ C G+C+
Sbjct: 457 INECHSDP--CQNDATCLDKIGGFTCLCMPGFK---GVHCELEINECQ-SNPCVNNGQCV 510
Query: 895 NTEGSFHCVCQQGFSISADGRTCE-DIDECVNNTVCDSHGFCDNTAGSFRCLCYQGFQAP 953
+ F C+C GF+ G C+ DID+C ++T C + C + + C C GF
Sbjct: 511 DKVNRFQCLCPPGFT----GPVCQIDIDDC-SSTPCLNGAKCIDHPNGYECQCATGF--- 562
Query: 954 QDGQGCVD-VNECELLSGVCGEAFCENVEGSFLCVCADENQEYSPMTGQCRSRTSTDLDV 1012
G C + ++ C+ C C++ S+ C+C N Y M C
Sbjct: 563 -TGVLCEENIDNCD--PDPCHHGQCQDGIDSYTCIC---NPGY--MGAIC---------- 604
Query: 1013 DVDQPKEEKKECYYN--LNDASLCDNVLAPNVTKQECCCTSGAGWGDNCEIFPCPVLGTA 1070
++ ECY + LND D V +C C G G NCEI
Sbjct: 605 -----SDQIDECYSSPCLNDGRCID-----LVNGYQCNCQPGTS-GVNCEINFDDCASNP 653
Query: 1071 EFTEMCPKGKGFVPAGESSSEAGGENYKDADECLLFGQEICKNG-FCLNTRPGYECYCKQ 1129
+C G S G D DEC C+ G C+N G+ C C +
Sbjct: 654 CIHGICMDGINRYSCVCSPGFTGQRCNIDIDEC---ASNPCRKGATCINGVNGFRCICPE 710
Query: 1130 GTYYDPVKLQCF-DMDECQDPSSCIDGQCVNTEGSYNCFCTHPMVLDASEKRCIRPAESN 1188
G ++ C+ ++EC + CI G C Y C C DA + N
Sbjct: 711 GPHHP----SCYSQVNECLS-NPCIHGNCTGGLSGYKCLC------DAGWVGINCEVDKN 759
Query: 1189 EQIEETDVYQDLCWEHLSDEYVCSRPLVGK----QTTYTEC----CCLYGEAWGMQCALC 1240
E + C ++L + Y C+ K Q EC C G +
Sbjct: 760 ECLSNPCQNGGTC-DNLVNGYRCTCKKGFKGYNCQVNIDECASNPCLNQGTCF------- 811
Query: 1241 PLKDSDDYAQLCNIPVTGRR----------QPYGRDALVDFS---EQYTPEADPYFIQDR 1287
D Y C +P TG+ P A+ S E YT P + R
Sbjct: 812 --DDISGYTCHCVLPYTGKNCQTVLAPCSPNPCENAAVCKESPNFESYTCLCAPGWQGQR 869
Query: 1288 FLNSFEELQAEECGILNGCENGRCVRVQEGYTCDCFDGYHLDTAKMTC-VDVNECDELNN 1346
+E ++ C +G C Q Y C+C G+ + M C D+++C
Sbjct: 870 CTIDIDECISKPC-----MNHGLCHNTQGSYMCECPPGF----SGMDCEEDIDDC----- 915
Query: 1347 RMSLCKN-AKCINTDGSYKCLCLPGY 1371
+ C+N C++ ++ CLCLPG+
Sbjct: 916 LANPCQNGGSCMDGVNTFSCLCLPGF 941
Score = 197 bits (502), Expect = 4e-50
Identities = 224/830 (26%), Positives = 327/830 (39%), Gaps = 160/830 (19%)
Query: 573 CICYEGYRFSEQQRKCVDIDECTQVQHLCSQGRCENTE--------GSFLCICPAGFMAS 624
C C EG+ + E Q + C + RC+N G C C +GF
Sbjct: 51 CKCPEGF-----------LGEYCQHRDPCEKNRCQNGGTCVAQAMLGKATCRCASGFTGE 99
Query: 625 E----EGTNCIDVDECLRPDVCGEGHCVNTVGAFRCEYCDSGYRMTQRGRCEDIDECLNP 680
+ C CL C H ++ + C C G+ + C+ D CL+
Sbjct: 100 DCQYSTSHPCFVSRPCLNGGTC---HMLSR-DTYECT-CQVGFTGKE---CQWTDACLSH 151
Query: 681 STCPDEQCVNSPGSYQCVPCTEGFRGWNGQCLDVDECLEPNVCANGD-CSNLEGSYMCSC 739
C + C C GF G + DV+EC P C +G C NL GSY C C
Sbjct: 152 PCANGSTCTTVANQFSC-KCLTGFTGQKCET-DVNECDIPGHCQHGGTCLNLPGSYQCQC 209
Query: 740 HKGYTRTPDHKHCRDIDECQQGNLCVNG-QCKNT-EGSFRCTCGQGYQLSAAKDQCEDID 797
+G+T ++C + + CVNG C+ T + +F C C G++ S + +ID
Sbjct: 210 PQGFTG----QYCDSLYVPCAPSPCVNGGTCRQTGDFTFECNCLPGFEGSTCE---RNID 262
Query: 798 ECQHRHLCAHGQCRNTEGSFQCVCDQGYRASGLGDHC-EDINECLEDKSVCQRGD-CINT 855
+C + G C + ++ C C + G C ED++ECL + CQ G C N
Sbjct: 263 DCPNHRCQNGGVCVDGVNTYNCRCPPQWT----GQFCTEDVDECLLQPNACQNGGTCANR 318
Query: 856 AGSYDCTCPDGFQLDDNKTCQDINECEHPGLCGPQGECLNTEGSFHCVCQQGFSISADGR 915
G Y C C +G+ DD ++I++C C P C++ SF C+C +G + G
Sbjct: 319 NGGYGCVCVNGWSGDD--CSENIDDCAFAS-CTPGSTCIDRVASFSCMCPEGKA----GL 371
Query: 916 TCEDIDECVNNTVCDSHGFCDNTA--GSFRCLCYQGFQAPQDGQGCV-DVNECELL-SGV 971
C D C++N C CD G + C C QG++ G C DV+EC + S
Sbjct: 372 LCHLDDACISNP-CHKGALCDTNPLNGQYICTCPQGYK----GADCTEDVDECAMANSNP 426
Query: 972 CGEAF-CENVEGSFLCVCADENQEYSPMTGQCRSRTSTDLDVDVDQPKEEKKECYYNLND 1030
C A C N +G+F C C + G R D++ P + ND
Sbjct: 427 CEHAGKCVNTDGAFHCEC---------LKGYAGPRCEMDINECHSDPCQ---------ND 468
Query: 1031 ASLCDNVLAPNVTKQECCCTSGAGWGDNCE--IFPC---PVLGTAEFTEMCPKGKGFVPA 1085
A+ D + C C G G +CE I C P + + + + + P
Sbjct: 469 ATCLDKIGGFT-----CLCMPGFK-GVHCELEINECQSNPCVNNGQCVDKVNRFQCLCPP 522
Query: 1086 GESSSEAGGENYKDADECLLFGQEICKNGF-CLNTRPGYECYCKQGTYYDPVKLQCFD-M 1143
G + G D D+C C NG C++ GYEC C G + C + +
Sbjct: 523 GFT----GPVCQIDIDDC---SSTPCLNGAKCIDHPNGYECQCATGF----TGVLCEENI 571
Query: 1144 DECQDPSSCIDGQCVNTEGSYNCFCTHPMVLDASEKRCIRPAESNEQIEETDVYQDLCWE 1203
D C DP C GQC + SY C C +P + A ++QI+E Y C
Sbjct: 572 DNC-DPDPCHHGQCQDGIDSYTCIC-NPGYMGAI---------CSDQIDEC--YSSPC-- 616
Query: 1204 HLSDEYVCSRPLVGKQTTYTECCCLYGEAWGMQCALCPLKDSDDYAQLCNIPVTGRRQPY 1263
L+D C + G Q C C G + G+ C + + DD A P
Sbjct: 617 -LNDGR-CIDLVNGYQ-----CNCQPGTS-GVNCEI----NFDDCAS----------NPC 654
Query: 1264 GRDALVDFSEQYTPEADPYFIQDRFLNSFEELQAEECGILNGCENGR-CVRVQEGYTCDC 1322
+D +Y+ P F R + +EC N C G C+ G+ C C
Sbjct: 655 IHGICMDGINRYSCVCSPGFTGQRC-----NIDIDECAS-NPCRKGATCINGVNGFRCIC 708
Query: 1323 FDGYHLDTAKMTCVDVNECDELNNRMSLCKNAKCINTDGSYKCLCLPGYV 1372
+G H + VNEC L+N C + C YKCLC G+V
Sbjct: 709 PEGPHHPSCYS---QVNEC--LSNP---CIHGNCTGGLSGYKCLCDAGWV 750
Score = 192 bits (487), Expect = 2e-48
Identities = 183/711 (25%), Positives = 276/711 (38%), Gaps = 136/711 (19%)
Query: 543 PTQVTEINECTVNPDICGAGHCINLPVRYTCICYEGYRFSEQQRKCVDIDECTQVQHLCS 602
P+ +++NEC NP C G+C Y C+C G+ + VD +EC + + C
Sbjct: 715 PSCYSQVNECLSNP--CIHGNCTGGLSGYKCLCDAGWVGINCE---VDKNEC--LSNPCQ 767
Query: 603 QG-RCENTEGSFLCICPAGFMASEEGTNC-IDVDECLRPDVCGEGHCVNTVGAFRCEYCD 660
G C+N + C C GF +G NC +++DEC +G C + + + C +C
Sbjct: 768 NGGTCDNLVNGYRCTCKKGF----KGYNCQVNIDECASNPCLNQGTCFDDISGYTC-HCV 822
Query: 661 SGYRMTQRGRCEDIDECLNPSTCPDEQ-CVNSPG--SYQCVPCTEGFRGWNGQ--CLDVD 715
Y C+ + +P+ C + C SP SY C+ C G W GQ +D+D
Sbjct: 823 LPYTGKN---CQTVLAPCSPNPCENAAVCKESPNFESYTCL-CAPG---WQGQRCTIDID 875
Query: 716 ECLEPNVCANGDCSNLEGSYMCSCHKGYTRTPDHKHCRDIDECQQGNLCVNG-QCKNTEG 774
EC+ +G C N +GSYMC C G++ + DID+C N C NG C +
Sbjct: 876 ECISKPCMNHGLCHNTQGSYMCECPPGFSGMDCEE---DIDDCL-ANPCQNGGSCMDGVN 931
Query: 775 SFRCTCGQGYQLSAAKDQCE-DIDECQHRHLCAHGQCRNTEGSFQCVCDQGYRASGLGDH 833
+F C C G+ D+C+ D++EC G C + S+ C C G+ G H
Sbjct: 932 TFSCLCLPGF----TGDKCQTDMNECLSEPCKNGGTCSDYVNSYTCKCQAGFD----GVH 983
Query: 834 CED-INECLEDKSVCQRGDCINTAGSYDCTCPDGFQLDDNKTCQDINECE-HPGLCGPQG 891
CE+ INEC E S G C++ S+ C CP GF + +INEC HP C +G
Sbjct: 984 CENNINECTES-SCFNGGTCVDGINSFSCLCPVGFT--GSFCLHEINECSSHP--CLNEG 1038
Query: 892 ECLNTEGSFHCVCQQGFSISADGRTCEDIDECVNNTVCDSHGFCDNTAGSFRCLCYQGFQ 951
C++ G++ C C G++ G+ C+ + + + C + G C +CLC G+
Sbjct: 1039 TCVDGLGTYRCSCPLGYT----GKNCQTLVNLCSRSPCKNKGTCVQKKAESQCLCPSGWA 1094
Query: 952 APQDGQGCVDVNECELLSGVCGEAFCENVEGSFLCVCADENQEYSPMTGQCRSRTSTDLD 1011
V + GV E C++ S +C+ A G S LD
Sbjct: 1095 GAYCDVPNVSCDIAASRRGVLVEHLCQH---SGVCINAGNTHYCQCPLGYTGSYCEEQLD 1151
Query: 1012 VDVDQPKEEKKEC--------------YYNLN---DASLCDNVLAPN-------VTKQEC 1047
P + C Y +N + C N N V +C
Sbjct: 1152 ECASNPCQHGATCSDFIGGYRCECVPGYQGVNCEYEVDECQNQPCQNGGTCIDLVNHFKC 1211
Query: 1048 CCTSGAGWGDNCEIFPCPVLGTAEFTEMCPKGKGFVPAGESSSEAGGENYK--------- 1098
C G G CE E + C +G + G+ GG + +
Sbjct: 1212 SCPPGTR-GLLCE----------ENIDDCARGPHCLNGGQCMDRIGGYSCRCLPGFAGER 1260
Query: 1099 ---DADECLLFGQEICKNGFCLNTRPGYECYCKQG-------TYYDPV-KLQCFDMDECQ 1147
D +ECL + C+ Y C C+ T+ D ++ C + C
Sbjct: 1261 CEGDINECLSNPCSSEGSLDCIQLTNDYLCVCRSAFTGRHCETFVDVCPQMPCLNGGTCA 1320
Query: 1148 DPSSCIDG---------------------------QCVNTEGSYNCFCTHP 1171
S+ DG QCV+T CFC P
Sbjct: 1321 VASNMPDGFICRCPPGFSGARCQSSCGQVKCRKGEQCVHTASGPRCFCPSP 1371
Score = 155 bits (391), Expect = 3e-37
Identities = 195/735 (26%), Positives = 281/735 (38%), Gaps = 174/735 (23%)
Query: 670 RCED-IDECLNPSTCPDEQCVNSPGSYQCVPCTEGFRGWNGQCLDVDECLEPNVCANGD- 727
+C D + C+N C G+ C C EGF G C D C E N C NG
Sbjct: 27 QCRDGYEPCVNEGMC----VTYHNGTGYC-KCPEGFLG--EYCQHRDPC-EKNRCQNGGT 78
Query: 728 --CSNLEGSYMCSCHKGYTRTPDHKHCRDIDECQQGNLCVNGQCKN--TEGSFRCTCGQG 783
+ G C C G+T D ++ C C+NG + + ++ CTC G
Sbjct: 79 CVAQAMLGKATCRCASGFTGE-DCQYSTS-HPCFVSRPCLNGGTCHMLSRDTYECTCQVG 136
Query: 784 YQLSAAKDQCEDIDECQHRHLCAHGQ-CRNTEGSFQCVCDQGYRASGLGDHCE-DINECL 841
+ +C+ D C H CA+G C F C C G+ G CE D+NEC
Sbjct: 137 F----TGKECQWTDACLS-HPCANGSTCTTVANQFSCKCLTGFT----GQKCETDVNEC- 186
Query: 842 EDKSVCQRGD-CINTAGSYDCTCPDGFQLDDNKTCQDINECEHPGLCGPQGECLNT-EGS 899
+ CQ G C+N GSY C CP GF + C + P C G C T + +
Sbjct: 187 DIPGHCQHGGTCLNLPGSYQCQCPQGFT---GQYCDSLYVPCAPSPCVNGGTCRQTGDFT 243
Query: 900 FHCVCQQGFSISADGRTCE-DIDECVNNTVCDSHGFCDNTAGSFRCLCYQGFQAPQ-DGQ 957
F C C GF +G TCE +ID+C N+ C + G C + ++ C C PQ GQ
Sbjct: 244 FECNCLPGF----EGSTCERNIDDCPNHR-CQNGGVCVDGVNTYNCRC-----PPQWTGQ 293
Query: 958 GCV-DVNECELLSGVCGEA-FCENVEGSFLCVCADENQEYSPMTGQCRSRTSTDLDVDVD 1015
C DV+EC L C C N G + CVC + S D
Sbjct: 294 FCTEDVDECLLQPNACQNGGTCANRNGGYGCVCVNG--------------WSGD------ 333
Query: 1016 QPKEEKKECYYNLNDASLCDNVLAPNVTKQECCCTSGAGWGDNCEIFPCPVLGTAEFTEM 1075
+C N++D + CT G+ D F C M
Sbjct: 334 -------DCSENIDDCAFAS-------------CTPGSTCIDRVASFSC----------M 363
Query: 1076 CPKGKGFVPAGESSSEAGGENYKDADECLLFGQEICKNGFCLNTRP---GYECYCKQGTY 1132
CP+GK AG + D D C+ C G +T P Y C C QG
Sbjct: 364 CPEGK-----------AGLLCHLD-DACI---SNPCHKGALCDTNPLNGQYICTCPQGYK 408
Query: 1133 YDPVKLQCF-DMDECQDPSS--CID-GQCVNTEGSYNCFCTHPMVLDASEKRCIRPAESN 1188
C D+DEC +S C G+CVNT+G+++C C + + RC
Sbjct: 409 ----GADCTEDVDECAMANSNPCEHAGKCVNTDGAFHCEC----LKGYAGPRC------- 453
Query: 1189 EQIEETDVYQDLCWEHLSDEYVCSRPLVGKQTTYTECCCLYGEAWGMQCALCPLKDSDDY 1248
+++ + + D C ++ C + G C C+ G G+ C L +
Sbjct: 454 -EMDINECHSDPC----QNDATCLDKIGG-----FTCLCMPGFK-GVHCEL-------EI 495
Query: 1249 AQLCNIPVTGRRQPYGRDALVDFSEQYTPEADPYFIQDRFLNSFEELQAEECGILNGCEN 1308
+ + P Q VD ++ P F ++ + C LNG
Sbjct: 496 NECQSNPCVNNGQ------CVDKVNRFQCLCPPGFTGPVCQIDIDDCSSTPC--LNGA-- 545
Query: 1309 GRCVRVQEGYTCDCFDGYHLDTAKMTCVDVNECDELNNRMSLCKNAKCINTDGSYKCLCL 1368
+C+ GY C C G+ T + +++ CD C + +C + SY C+C
Sbjct: 546 -KCIDHPNGYECQCATGF---TGVLCEENIDNCDP-----DPCHHGQCQDGIDSYTCICN 596
Query: 1369 PGY---VPSDKPNYC 1380
PGY + SD+ + C
Sbjct: 597 PGYMGAICSDQIDEC 611
Score = 150 bits (380), Expect = 6e-36
Identities = 168/723 (23%), Positives = 273/723 (37%), Gaps = 136/723 (18%)
Query: 710 QCLD-VDECLEPNVCANGDCSNLEGSYMCSCHKGYTRTPDHKHCRDIDECQQGNLCVNGQ 768
QC D + C+ +C G+ C C +G+ ++C+ D C++ N C NG
Sbjct: 27 QCRDGYEPCVNEGMCVTYH----NGTGYCKCPEGFLG----EYCQHRDPCEK-NRCQNGG 77
Query: 769 CKNTE---GSFRCTCGQGYQLSAAKDQCEDIDECQHRHLCAHGQCRN--TEGSFQCVCDQ 823
+ G C C G+ + Q C C +G + + +++C C
Sbjct: 78 TCVAQAMLGKATCRCASGF--TGEDCQYSTSHPCFVSRPCLNGGTCHMLSRDTYECTCQV 135
Query: 824 GYRASGLGDHCEDINECLEDKSVCQRGD-CINTAGSYDCTCPDGFQLDDNKTCQDINECE 882
G+ G C+ + CL C G C A + C C GF +T D+NEC+
Sbjct: 136 GFT----GKECQWTDACLSHP--CANGSTCTTVANQFSCKCLTGFTGQKCET--DVNECD 187
Query: 883 HPGLCGPQGECLNTEGSFHCVCQQGFS--------------------------------- 909
PG C G CLN GS+ C C QGF+
Sbjct: 188 IPGHCQHGGTCLNLPGSYQCQCPQGFTGQYCDSLYVPCAPSPCVNGGTCRQTGDFTFECN 247
Query: 910 --ISADGRTCE-DIDECVNNTVCDSHGFCDNTAGSFRCLCYQGFQAPQ-DGQGCV-DVNE 964
+G TCE +ID+C N+ C + G C + ++ C C PQ GQ C DV+E
Sbjct: 248 CLPGFEGSTCERNIDDCPNHR-CQNGGVCVDGVNTYNCRC-----PPQWTGQFCTEDVDE 301
Query: 965 CELLSGVC-GEAFCENVEGSFLCVCAD--ENQEYSPMTGQCRSRTSTDLDVDVDQPKEEK 1021
C L C C N G + CVC + + S C + T +D +
Sbjct: 302 CLLQPNACQNGGTCANRNGGYGCVCVNGWSGDDCSENIDDCAFASCTPGSTCID--RVAS 359
Query: 1022 KECYYNLNDASLCDNVLAPNVTKQECCCTSGAGWGDNCEIFPCPVLGTAEFTEMCPKGKG 1081
C A L ++ + C ++ G C+ P ++ CP+G
Sbjct: 360 FSCMCPEGKAGLLCHL-------DDACISNPCHKGALCDTNPL----NGQYICTCPQG-- 406
Query: 1082 FVPAGESSSEAGGENYKDADECLLFGQEICKN-GFCLNTRPGYECYCKQGTYYDPVKLQC 1140
G + +D DEC + C++ G C+NT + C C +G Y P +C
Sbjct: 407 ---------YKGADCTEDVDECAMANSNPCEHAGKCVNTDGAFHCECLKG-YAGP---RC 453
Query: 1141 -FDMDECQDPSSCIDGQCVNTEGSYNCFCTHPM-----VLDASEKRCIRPAESNEQIEET 1194
D++EC D C++ G + C C L+ +E + + + +++
Sbjct: 454 EMDINECHSDPCQNDATCLDKIGGFTCLCMPGFKGVHCELEINECQSNPCVNNGQCVDKV 513
Query: 1195 DVYQDLCWEHLSDEYVCSRPLVGKQTTYTEC-----CCLYGEAWGMQCALCPLKDSDDYA 1249
+ +Q LC + VC + + T C C + + QCA +
Sbjct: 514 NRFQCLCPPGFTGP-VCQIDI--DDCSSTPCLNGAKCIDHPNGYECQCA------TGFTG 564
Query: 1250 QLCNIPVTG-RRQPYGRDALVDFSEQYTPEADPYFIQDRFLNSFEELQAEECGILNGCEN 1308
LC + P D + YT +P ++ + +E + C +
Sbjct: 565 VLCEENIDNCDPDPCHHGQCQDGIDSYTCICNPGYMGAICSDQIDECYSSPC-----LND 619
Query: 1309 GRCVRVQEGYTCDCFDGYHLDTAKMTCVDVNECDELNNRMSLCKNAKCINTDGSYKCLCL 1368
GRC+ + GY C+C G T+ + C ++N D +N C + C++ Y C+C
Sbjct: 620 GRCIDLVNGYQCNCQPG----TSGVNC-EINFDDCASNP---CIHGICMDGINRYSCVCS 671
Query: 1369 PGY 1371
PG+
Sbjct: 672 PGF 674
Score = 100 bits (249), Expect = 1e-20
Identities = 93/322 (28%), Positives = 129/322 (40%), Gaps = 53/322 (16%)
Query: 561 AGHCINLPVRYTCICYEGYRFSEQQRKCVDIDECTQVQHLCSQGR-CENTEGSFLCICPA 619
+G CIN + C C GY S + + +DEC + C G C + G + C C
Sbjct: 1123 SGVCINAGNTHYCQCPLGYTGSYCEEQ---LDECAS--NPCQHGATCSDFIGGYRCECVP 1177
Query: 620 GFMASEEGTNC-IDVDECLRPDVCGEGHCVNTVGAFRCEYCDSGYRMTQRGRCED-IDEC 677
G+ +G NC +VDEC G C++ V F+C C G T+ CE+ ID+C
Sbjct: 1178 GY----QGVNCEYEVDECQNQPCQNGGTCIDLVNHFKCS-CPPG---TRGLLCEENIDDC 1229
Query: 678 LNPSTCPDE-QCVNSPGSYQCVPCTEGFRGWNGQCLDVDECLEPNVCANG--DCSNLEGS 734
C + QC++ G Y C C GF G + D++ECL + G DC L
Sbjct: 1230 ARGPHCLNGGQCMDRIGGYSC-RCLPGFAGERCEG-DINECLSNPCSSEGSLDCIQLTND 1287
Query: 735 YMCSCHKGYTRTPDHKHCRD-IDECQQGNLCVNGQC---KNTEGSFRCTCGQGYQLSAAK 790
Y+C C +T +HC +D C Q G C N F C C G+ + +
Sbjct: 1288 YLCVCRSAFT----GRHCETFVDVCPQMPCLNGGTCAVASNMPDGFICRCPPGFSGARCQ 1343
Query: 791 DQCEDIDECQHRHLCAHGQCRNTEGSFQCVCDQGYRASGLGDHCEDINECLED--KSVCQ 848
C + +CR E QCV + ASG C +C S CQ
Sbjct: 1344 SSCGQV------------KCRKGE---QCV----HTASGPRCFCPSPRDCESGCASSPCQ 1384
Query: 849 RGDCINTAGS---YDCTCPDGF 867
G + Y C C F
Sbjct: 1385 HGGSCHPQRQPPYYSCQCAPPF 1406
Score = 55.1 bits (131), Expect = 5e-07
Identities = 37/119 (31%), Positives = 51/119 (42%), Gaps = 13/119 (10%)
Query: 231 GRCFQETIGSQCGKALPGLSKQEDCCGTVGTSWGFNKCQK---CPKKPSYHGYNQMMECL 287
G CF + G C LP K C TV N C+ C + P++ Y + C
Sbjct: 808 GTCFDDISGYTCHCVLPYTGKN---CQTVLAPCSPNPCENAAVCKESPNFESYTCL--CA 862
Query: 288 PGYKRVNNTFCQDINECQLQGVCPNGECLNTMGSYRCTCKIGFGP---DPTFSSCVPDP 343
PG++ T DI+EC + +G C NT GSY C C GF + C+ +P
Sbjct: 863 PGWQGQRCTI--DIDECISKPCMNHGLCHNTQGSYMCECPPGFSGMDCEEDIDDCLANP 919
Score = 45.8 bits (107), Expect = 3e-04
Identities = 26/66 (39%), Positives = 34/66 (51%), Gaps = 8/66 (12%)
Query: 285 ECLPGYKRVNNTFCQ-DINECQLQGVCPNG-ECLNTMGSYRCTCKIGFGP---DPTFSSC 339
+CL G+ C+ D+NEC + G C +G CLN GSY+C C GF D + C
Sbjct: 169 KCLTGF---TGQKCETDVNECDIPGHCQHGGTCLNLPGSYQCQCPQGFTGQYCDSLYVPC 225
Query: 340 VPDPPV 345
P P V
Sbjct: 226 APSPCV 231
Score = 45.8 bits (107), Expect = 3e-04
Identities = 36/112 (32%), Positives = 44/112 (39%), Gaps = 24/112 (21%)
Query: 22 HTGRIKVVFTPSICKVTCTKGSCQNSCEKG----------NTTTLISENGHAADTLTATN 71
H G K V T C KG CE N T + + G L
Sbjct: 429 HAG--KCVNTDGAFHCECLKGYAGPRCEMDINECHSDPCQNDATCLDKIG-GFTCLCMPG 485
Query: 72 FRVVICHL--------PCMNGGQCS---SRDKCQCPPNFTGKLCQIPVHGAS 112
F+ V C L PC+N GQC +R +C CPP FTG +CQI + S
Sbjct: 486 FKGVHCELEINECQSNPCVNNGQCVDKVNRFQCLCPPGFTGPVCQIDIDDCS 537
Score = 45.4 bits (106), Expect = 4e-04
Identities = 82/359 (22%), Positives = 126/359 (35%), Gaps = 80/359 (22%)
Query: 81 CMNGGQCS---SRDKCQCPPNFTGKLCQIPVHGASV-PKLYQHSQQPGKALGTHVIHSTH 136
C NGG C + C CP FTG C ++ S P L + + G LGT+
Sbjct: 996 CFNGGTCVDGINSFSCLCPVGFTGSFCLHEINECSSHPCLNEGTCVDG--LGTYRC---- 1049
Query: 137 TLPLTVTSQQGVKVKFPPNIVNIHVKHPPE---ASVQIHQVSRIDGPTGQKTKEAQPGQS 193
+ PL T K +VN+ + P + VQ S+ P+G A
Sbjct: 1050 SCPLGYTG------KNCQTLVNLCSRSPCKNKGTCVQKKAESQCLCPSGWAG--AYCDVP 1101
Query: 194 QVSYQGLPVQKTQTIHSTYSHQQVIPHVYPVAAKTQLGRCFQETIGSQCGKALPGLSKQE 253
VS ++ + H V + A T +C GS C + L +
Sbjct: 1102 NVSCDIAASRRGVLVEHLCQHSGVCIN----AGNTHYCQCPLGYTGSYCEEQL------D 1151
Query: 254 DCCGTVGTSWGFNKCQKCPKKPSYHGYNQMMECLPGYKRVNNTFCQDINECQLQGVCPNG 313
+C N CQ + G EC+PGY+ VN + +++ECQ Q G
Sbjct: 1152 ECAS--------NPCQHGATCSDFIG-GYRCECVPGYQGVNCEY--EVDECQNQPCQNGG 1200
Query: 314 ECLNTMGSYRCTCKIGFGP---DPTFSSCVPDPPVISEEKGPCYRLVS----------SG 360
C++ + ++C+C G + C P ++ G C + +G
Sbjct: 1201 TCIDLVNHFKCSCPPGTRGLLCEENIDDCARGPHCLN--GGQCMDRIGGYSCRCLPGFAG 1258
Query: 361 RQC--------MHPLS-------VHLTKQLCCCSVGKAWGPHCEKCPLPGTAAFKEICP 404
+C +P S + LT C G HCE F ++CP
Sbjct: 1259 ERCEGDINECLSNPCSSEGSLDCIQLTNDYLCVCRSAFTGRHCE--------TFVDVCP 1309
Score = 42.0 bits (97), Expect = 0.004
Identities = 20/49 (40%), Positives = 31/49 (63%), Gaps = 5/49 (10%)
Query: 286 CLPGYKRVNNTFCQ-DINECQLQGVCPNGECLNTMGSYRCTCKIGF-GP 332
C+PG+K V+ C+ +INECQ NG+C++ + ++C C GF GP
Sbjct: 482 CMPGFKGVH---CELEINECQSNPCVNNGQCVDKVNRFQCLCPPGFTGP 527
Score = 40.8 bits (94), Expect = 0.009
Identities = 38/148 (25%), Positives = 56/148 (37%), Gaps = 22/148 (14%)
Query: 271 CPKKPSYHGYNQ------MMECLPGYKRVNNTFCQD-INECQLQGVCPNGECLNTMGSYR 323
C P +HG Q C PGY C D I+EC +G C++ + Y+
Sbjct: 574 CDPDPCHHGQCQDGIDSYTCICNPGYM---GAICSDQIDECYSSPCLNDGRCIDLVNGYQ 630
Query: 324 CTCK---IGFGPDPTFSSCVPDPPVISEEKGPCYRLVSSGRQCMHPLSVHLTKQLCCCSV 380
C C+ G + F C +P + G C ++ C+ S T Q C +
Sbjct: 631 CNCQPGTSGVNCEINFDDCASNPCI----HGICMDGINR-YSCV--CSPGFTGQRCNIDI 683
Query: 381 GKAWGPHCEK--CPLPGTAAFKEICPGG 406
+ C K + G F+ ICP G
Sbjct: 684 DECASNPCRKGATCINGVNGFRCICPEG 711
Score = 39.7 bits (91), Expect = 0.020
Identities = 82/350 (23%), Positives = 118/350 (33%), Gaps = 78/350 (22%)
Query: 1057 DNCEIFPCPVLGTAEFTEMCPKGKGFVPAGESSSEAGGENYKDADECLLFGQEICKNGFC 1116
D CE C GT M K +G + + Y + C F C NG
Sbjct: 66 DPCEKNRCQNGGTCVAQAMLGKATCRCASGFTGEDC---QYSTSHPC--FVSRPCLNGGT 120
Query: 1117 LN--TRPGYECYCKQGTYYDPVKLQCFDMDECQDPSSCIDGQCVN------TEGSYNCFC 1168
+ +R YEC C+ G F ECQ +C+ C N ++C C
Sbjct: 121 CHMLSRDTYECTCQVG----------FTGKECQWTDACLSHPCANGSTCTTVANQFSCKC 170
Query: 1169 THPMVLDASEKRCIRPAESNEQIEETDVYQDLCWEHLSDEYVCSRPLVGKQTTYTECCCL 1228
+ + ++C ETDV + C P G C L
Sbjct: 171 ----LTGFTGQKC-----------ETDVNE------------CDIP--GHCQHGGTCLNL 201
Query: 1229 YGEAWGMQCALCPLKDSDDYAQLCNIPVTGRRQPYGRDALVDFSEQYTPEADPYFIQDRF 1288
G QC CP + Y +P P + +T E + F
Sbjct: 202 PGS---YQCQ-CPQGFTGQYCDSLYVPCAP--SPCVNGGTCRQTGDFTFECN---CLPGF 252
Query: 1289 LNSFEELQAEECGILNGCENGR-CVRVQEGYTCDCFDGYHLDTAKMTCVDVNECDELNNR 1347
S E ++C + C+NG CV Y C C + T + DV+EC N
Sbjct: 253 EGSTCERNIDDCPN-HRCQNGGVCVDGVNTYNCRCPPQW---TGQFCTEDVDECLLQPNA 308
Query: 1348 MSLCKNA-KCINTDGSYKCLCLPGYVPSDKPN--------YCTPLNTALN 1388
C+N C N +G Y C+C+ G+ D CTP +T ++
Sbjct: 309 ---CQNGGTCANRNGGYGCVCVNGWSGDDCSENIDDCAFASCTPGSTCID 355
Score = 38.9 bits (89), Expect = 0.035
Identities = 28/87 (32%), Positives = 41/87 (47%), Gaps = 13/87 (14%)
Query: 266 NKCQK---CPKKPSYHGYNQMMECLPGYKRVNNTFCQDINECQLQGVCP---NGECLNTM 319
N C K C P Y + C GYK + T +D++EC + P G+C+NT
Sbjct: 382 NPCHKGALCDTNPLNGQY--ICTCPQGYKGADCT--EDVDECAMANSNPCEHAGKCVNTD 437
Query: 320 GSYRCTCKIGF-GP--DPTFSSCVPDP 343
G++ C C G+ GP + + C DP
Sbjct: 438 GAFHCECLKGYAGPRCEMDINECHSDP 464
Score = 38.5 bits (88), Expect = 0.046
Identities = 56/257 (21%), Positives = 94/257 (36%), Gaps = 48/257 (18%)
Query: 80 PCMNGGQCSS---RDKCQCPPNFTGKLCQIPVHGASVPKLYQHSQQPGKALGTHVIHSTH 136
PC NG C++ + C+C FTG+ C+ V+ +P H Q G L
Sbjct: 152 PCANGSTCTTVANQFSCKCLTGFTGQKCETDVNECDIP---GHCQHGGTCL--------- 199
Query: 137 TLPLTVTSQ--QGVKVKFPPNIVNIHVKHPPEASVQIHQVSRIDGPTGQKTKEAQ--PGQ 192
LP + Q QG ++ +++V P V + TG T E PG
Sbjct: 200 NLPGSYQCQCPQGFTGQY---CDSLYVPCAPSPCVNGGTCRQ----TGDFTFECNCLPG- 251
Query: 193 SQVSYQGLPVQKTQTIHSTYSHQQVIPHVYPVAAKTQLGRCFQETIGSQCGKALPGLSKQ 252
++G ++ I +H+ V T RC + G C + + Q
Sbjct: 252 ----FEGSTCER--NIDDCPNHRCQNGGVCVDGVNTYNCRCPPQWTGQFCTEDVDECLLQ 305
Query: 253 EDCCGTVGTSWGFNKCQKCPKKPSYHGYNQMMECLPGYKRVNNTFCQDINECQLQGVCPN 312
+ C GT C + +G C+ G+ + ++I++C P
Sbjct: 306 PNACQNGGT---------CANRNGGYG----CVCVNGWS--GDDCSENIDDCAFASCTPG 350
Query: 313 GECLNTMGSYRCTCKIG 329
C++ + S+ C C G
Sbjct: 351 STCIDRVASFSCMCPEG 367
Score = 38.5 bits (88), Expect = 0.046
Identities = 42/129 (32%), Positives = 50/129 (38%), Gaps = 31/129 (24%)
Query: 297 FC-QDINECQLQ-GVCPNG-ECLNTMGSYRCTCKIGFGPDP--------TFSSCVPDPPV 345
FC +D++EC LQ C NG C N G Y C C G+ D F+SC P
Sbjct: 294 FCTEDVDECLLQPNACQNGGTCANRNGGYGCVCVNGWSGDDCSENIDDCAFASCTPG--- 350
Query: 346 ISEEKGPCYRLVSSGRQCMHP-----LSVHLTKQLCCCSVGKAWGPHCEKCPLPGTAAFK 400
C V+S CM P L HL C S G C+ PL G +
Sbjct: 351 -----STCIDRVAS-FSCMCPEGKAGLLCHLDD--ACISNPCHKGALCDTNPLNG----Q 398
Query: 401 EICPGGMGY 409
IC GY
Sbjct: 399 YICTCPQGY 407
Score = 38.5 bits (88), Expect = 0.046
Identities = 30/81 (37%), Positives = 38/81 (46%), Gaps = 22/81 (27%)
Query: 271 CPKKPSYHG-YNQMMECLP-------------GYKRVNNTF-----CQ-DINECQLQGVC 310
CP+ P + Y+Q+ ECL GYK + + C+ D NEC L C
Sbjct: 708 CPEGPHHPSCYSQVNECLSNPCIHGNCTGGLSGYKCLCDAGWVGINCEVDKNEC-LSNPC 766
Query: 311 PNG-ECLNTMGSYRCTCKIGF 330
NG C N + YRCTCK GF
Sbjct: 767 QNGGTCDNLVNGYRCTCKKGF 787
Score = 38.5 bits (88), Expect = 0.046
Identities = 82/349 (23%), Positives = 117/349 (33%), Gaps = 75/349 (21%)
Query: 80 PCMNGGQCSSRD---KCQCPPNFTGKLCQIPVHG-ASVPKLYQHSQQPGKALGTHVIHST 135
PC NGG C + +C C F G CQ+ + AS P L Q G ++
Sbjct: 765 PCQNGGTCDNLVNGYRCTCKKGFKGYNCQVNIDECASNPCLNQ-----GTCFDDISGYTC 819
Query: 136 H-TLPLTVTSQQGVKVKFPPNIVNIHVKHPPEASVQIHQVSRIDGPTGQK-TKEAQPGQS 193
H LP T + Q V PN + + + G GQ+ T + S
Sbjct: 820 HCVLPYTGKNCQTVLAPCSPNPCENAAVCKESPNFESYTCLCAPGWQGQRCTIDIDECIS 879
Query: 194 QVSYQGLPVQKTQTIHSTYSHQQVIPHVYPVAAKTQLGRCFQETIGSQCGKALPGLSKQE 253
+ P H+T Q + +C G+ +E
Sbjct: 880 K------PCMNHGLCHNT-----------------------QGSYMCECPPGFSGMDCEE 910
Query: 254 DCCGTVGTSWGFNKCQKCPKKPSYHGYNQMM-ECLPGYKRVNNTFCQ-DINECQLQGVCP 311
D + N CQ G N CLPG+ CQ D+NEC +
Sbjct: 911 DIDDCLA-----NPCQNGGS--CMDGVNTFSCLCLPGF---TGDKCQTDMNECLSEPCKN 960
Query: 312 NGECLNTMGSYRCTCKIGFG--------PDPTFSSCVPDPPVISEEKGPCYRLVSSGRQC 363
G C + + SY C C+ GF + T SSC G C ++S C
Sbjct: 961 GGTCSDYVNSYTCKCQAGFDGVHCENNINECTESSCF--------NGGTCVDGINS-FSC 1011
Query: 364 MHPLSVHLTKQLCCCSVGKAWGPHC--EKCPLPGTAAFKEICPGGMGYT 410
+ P V T C + + C E + G ++ CP +GYT
Sbjct: 1012 LCP--VGFTGSFCLHEINECSSHPCLNEGTCVDGLGTYRCSCP--LGYT 1056
Score = 37.7 bits (86), Expect = 0.078
Identities = 26/77 (33%), Positives = 32/77 (41%), Gaps = 11/77 (14%)
Query: 39 CTKGSCQNS------CEKGNTTTLISENGHAADTLTATNFRVVICHLPCMNGGQCS--SR 90
C K CQN G T + D +T+ + PC+NGG C SR
Sbjct: 68 CEKNRCQNGGTCVAQAMLGKATCRCASGFTGEDCQYSTSHPCFVSR-PCLNGGTCHMLSR 126
Query: 91 D--KCQCPPNFTGKLCQ 105
D +C C FTGK CQ
Sbjct: 127 DTYECTCQVGFTGKECQ 143
Score = 37.4 bits (85), Expect = 0.10
Identities = 16/39 (41%), Positives = 22/39 (56%), Gaps = 7/39 (17%)
Query: 74 VVIC-HLPCMNGGQCSSRDK------CQCPPNFTGKLCQ 105
V +C +PC+NGG C+ C+CPP F+G CQ
Sbjct: 1305 VDVCPQMPCLNGGTCAVASNMPDGFICRCPPGFSGARCQ 1343
Score = 36.6 bits (83), Expect = 0.17
Identities = 27/87 (31%), Positives = 39/87 (44%), Gaps = 18/87 (20%)
Query: 35 CKVTCTKGSCQ-------NSCEKGNTTTLISENGHAADTLTATNFR-----VVICHLP-- 80
C+V T CQ + C G+T T ++ N + LT + V C +P
Sbjct: 133 CQVGFTGKECQWTDACLSHPCANGSTCTTVA-NQFSCKCLTGFTGQKCETDVNECDIPGH 191
Query: 81 CMNGGQCSSRD---KCQCPPNFTGKLC 104
C +GG C + +CQCP FTG+ C
Sbjct: 192 CQHGGTCLNLPGSYQCQCPQGFTGQYC 218
Score = 35.4 bits (80), Expect = 0.39
Identities = 26/103 (25%), Positives = 44/103 (42%), Gaps = 23/103 (22%)
Query: 19 VSNHTGRIKVVFTPSICKVT---CTKGSCQNS--CEKGNTTTLISENGHAADTLTATNFR 73
+S +T + +T C+ C+ C+N+ C++ S N + L A ++
Sbjct: 814 ISGYTCHCVLPYTGKNCQTVLAPCSPNPCENAAVCKE-------SPNFESYTCLCAPGWQ 866
Query: 74 VVICHL--------PCMNGGQCSSRD---KCQCPPNFTGKLCQ 105
C + PCMN G C + C+CPP F+G C+
Sbjct: 867 GQRCTIDIDECISKPCMNHGLCHNTQGSYMCECPPGFSGMDCE 909
Score = 34.3 bits (77), Expect = 0.86
Identities = 18/47 (38%), Positives = 23/47 (48%), Gaps = 4/47 (8%)
Query: 285 ECLPGYKRVNNTFCQ-DINECQLQGVCPNGECLNTMGSYRCTCKIGF 330
ECL GY C+ DINEC + CL+ +G + C C GF
Sbjct: 443 ECLKGYAGPR---CEMDINECHSDPCQNDATCLDKIGGFTCLCMPGF 486
Score = 34.3 bits (77), Expect = 0.86
Identities = 14/29 (48%), Positives = 16/29 (55%), Gaps = 3/29 (10%)
Query: 80 PCMNGGQCS---SRDKCQCPPNFTGKLCQ 105
PC NGG C + KC CPP G LC+
Sbjct: 1195 PCQNGGTCIDLVNHFKCSCPPGTRGLLCE 1223
Score = 33.5 bits (75), Expect = 1.5
Identities = 13/29 (44%), Positives = 17/29 (58%), Gaps = 3/29 (10%)
Query: 80 PCMNGGQCSSRD---KCQCPPNFTGKLCQ 105
PC+NG +C +CQC FTG LC+
Sbjct: 540 PCLNGAKCIDHPNGYECQCATGFTGVLCE 568
Score = 33.1 bits (74), Expect = 1.9
Identities = 18/62 (29%), Positives = 26/62 (41%), Gaps = 7/62 (11%)
Query: 286 CLPGYKRVNNTFCQ-DINECQLQGVCPNGECLNTMGSYRCTCKIGFGP---DPTFSSCVP 341
C PG+ CQ DI++C +C++ Y C C GF + +C P
Sbjct: 520 CPPGF---TGPVCQIDIDDCSSTPCLNGAKCIDHPNGYECQCATGFTGVLCEENIDNCDP 576
Query: 342 DP 343
DP
Sbjct: 577 DP 578
Score = 33.1 bits (74), Expect = 1.9
Identities = 14/40 (35%), Positives = 20/40 (50%), Gaps = 5/40 (12%)
Query: 80 PCMNGGQCSSRDK-----CQCPPNFTGKLCQIPVHGASVP 114
PC +GG C + + CQC P F+G C++ S P
Sbjct: 1382 PCQHGGSCHPQRQPPYYSCQCAPPFSGSRCELYTAPPSTP 1421
Score = 32.7 bits (73), Expect = 2.5
Identities = 32/123 (26%), Positives = 47/123 (38%), Gaps = 19/123 (15%)
Query: 236 ETIGSQC--GKALPGLSKQEDCC--GTVGTSWGFNKCQKCPKKPSYHG-------YNQMM 284
E + + C G GLS + C G VG + +K +C P +G
Sbjct: 723 ECLSNPCIHGNCTGGLSGYKCLCDAGWVGINCEVDK-NECLSNPCQNGGTCDNLVNGYRC 781
Query: 285 ECLPGYKRVNNTFCQ-DINECQLQGVCPNGECLNTMGSYRCTCKI---GFGPDPTFSSCV 340
C G+K N CQ +I+EC G C + + Y C C + G + C
Sbjct: 782 TCKKGFKGYN---CQVNIDECASNPCLNQGTCFDDISGYTCHCVLPYTGKNCQTVLAPCS 838
Query: 341 PDP 343
P+P
Sbjct: 839 PNP 841
Score = 32.3 bits (72), Expect = 3.3
Identities = 22/68 (32%), Positives = 27/68 (39%), Gaps = 16/68 (23%)
Query: 42 GSCQNSCEKGNTTTLISENGHAADTLTATNFRVVICHLPCMNGGQCSSRD----KCQCPP 97
GS Q C +G T G D+L V PC+NGG C +C C P
Sbjct: 203 GSYQCQCPQGFT-------GQYCDSLY-----VPCAPSPCVNGGTCRQTGDFTFECNCLP 250
Query: 98 NFTGKLCQ 105
F G C+
Sbjct: 251 GFEGSTCE 258
Score = 32.0 bits (71), Expect = 4.3
Identities = 20/63 (31%), Positives = 24/63 (38%), Gaps = 12/63 (19%)
Query: 80 PCMNGGQC---SSRDKCQCPPNFTGKLCQIP---------VHGASVPKLYQHSQQPGKAL 127
PC N G C + +C CP + G C +P G V L QHS A
Sbjct: 1071 PCKNKGTCVQKKAESQCLCPSGWAGAYCDVPNVSCDIAASRRGVLVEHLCQHSGVCINAG 1130
Query: 128 GTH 130
TH
Sbjct: 1131 NTH 1133
Score = 30.8 bits (68), Expect = 9.5
Identities = 12/30 (40%), Positives = 16/30 (53%), Gaps = 4/30 (13%)
Query: 80 PCMNGGQC----SSRDKCQCPPNFTGKLCQ 105
PC+N G C + C+CP F G+ CQ
Sbjct: 34 PCVNEGMCVTYHNGTGYCKCPEGFLGEYCQ 63
>gi|134244285 Notch homolog 3 [Homo sapiens]
Length = 2321
Score = 229 bits (583), Expect = 2e-59
Identities = 242/909 (26%), Positives = 346/909 (38%), Gaps = 176/909 (19%)
Query: 543 PTQVTEINECTVNPDIC-GAGHCINLPVRYTCICYEGYRFSEQQRKCVDIDECTQVQHLC 601
P T++NEC P C C++ ++TCIC G+ + + VDIDEC Q
Sbjct: 426 PRCETDVNECLSGP--CRNQATCLDRIGQFTCICMAGFTGTYCE---VDIDEC-QSSPCV 479
Query: 602 SQGRCENTEGSFLCICPAGFMAS--------------EEGTNCID--------------- 632
+ G C++ F C CP+GF S G C+D
Sbjct: 480 NGGVCKDRVNGFSCTCPSGFSGSTCQLDVDECASTPCRNGAKCVDQPDGYECRCAEGFEG 539
Query: 633 ------VDECLRPDVCGEGHCVNTVGAFRCEYCDSGYRMTQRGRCED-IDECLNPSTCPD 685
VD+C PD C G CV+ + +F C C GY T RCE +DEC +
Sbjct: 540 TLCDRNVDDC-SPDPCHHGRCVDGIASFSCA-CAPGYTGT---RCESQVDECRSQPCRHG 594
Query: 686 EQCVNSPGSYQCVPCTEGFRGWNGQCLDVDECLEPNVCANGDCSNLEGSYMCSCHKGYTR 745
+C++ Y C C G G N + +++D+C N C G C + Y C C G+T
Sbjct: 595 GKCLDLVDKYLC-RCPSGTTGVNCE-VNIDDCAS-NPCTFGVCRDGINRYDCVCQPGFTG 651
Query: 746 TPDHKHCRDIDECQQGNLCVNGQCKNTEGSFRCTCGQGYQLSAAKDQCEDIDECQHRHLC 805
+ +I+EC G C + E FRC C G S C H C
Sbjct: 652 PLCNV---EINECASSPCGEGGSCVDGENGFRCLCPPG---SLPPLCLPPSHPCAHEP-C 704
Query: 806 AHGQCRNTEGSFQCVCDQGYRASGLGDHCED--INECLEDKSVCQRGDCINTAGSYDCTC 863
+HG C + G F+CVC+ G+ G C + E + G C + + CTC
Sbjct: 705 SHGICYDAPGGFRCVCEPGWS----GPRCSQSLARDACESQPCRAGGTCSSDGMGFHCTC 760
Query: 864 PDGFQLDDNKTCQDINECEHPGLCGPQGECLNTEGSFH-CVCQQGFSISADGRTCE-DID 921
P G Q + C+ ++ C P C G C + G C C QG+ G C+ D+D
Sbjct: 761 PPGVQ---GRQCELLSPCT-PNPCEHGGRCESAPGQLPVCSCPQGWQ----GPRCQQDVD 812
Query: 922 ECVNNTVCDSHGFCDNTAGSFRCLCYQGFQAPQDGQGCVDVNECELLSGVCGEAFCENVE 981
EC C HG C N AGSF C C+ G+ P Q D+N+C+ + G + C++
Sbjct: 813 ECAGPAPCGPHGICTNLAGSFSCTCHGGYTGPSCDQ---DINDCDPNPCLNGGS-CQDGV 868
Query: 982 GSFLCVCADENQEYSPMTGQCRSRTSTDLDVDVDQPKEEKKECYYNLNDASLCDNVLAPN 1041
GSF C C + G R + D+D EC N C + +
Sbjct: 869 GSFSCSC---------LPGFAGPRCARDVD-----------ECLSNPCGPGTCTD----H 904
Query: 1042 VTKQECCCTSGAGWGDNCE--IFPCP----------VLGTAEFTEMCPKGKGFVPAGESS 1089
V C C G G G +CE + C V G F+ +C G
Sbjct: 905 VASFTCTCPPGYG-GFHCEQDLPDCSPSSCFNGGTCVDGVNSFSCLCRPG---------- 953
Query: 1090 SEAGGENYKDADECLLFGQEICKNGFCLNTRPGYECYCKQGTYYDPVKLQCFDM-DECQD 1148
G +AD CL + G C PG+ C C + ++ P QC + D C
Sbjct: 954 -YTGAHCQHEADPCL--SRPCLHGGVCSAAHPGFRCTCLE-SFTGP---QCQTLVDWCSR 1006
Query: 1149 PSSCIDGQCVNTEGSYNCFCTHPMVLDASEKRCIRPAESNEQI----EETDVYQDLCWEH 1204
G+CV T G+Y C C + R + E+ QI E+ C +
Sbjct: 1007 QPCQNGGRCVQT-GAY-CLCPPGWSGRLCDIRSLPCREAAAQIGVRLEQLCQAGGQCVDE 1064
Query: 1205 LSDEY-VCSRPLVGKQTTYTECCCL----------YGEAWGMQCALCPLKDSDDYAQLCN 1253
S Y VC G CL G G C P + D+ +
Sbjct: 1065 DSSHYCVCPEGRTGSHCEQEVDPCLAQPCQHGGTCRGYMGGYMCECLPGYNGDNCED--D 1122
Query: 1254 IPVTGRRQPYGRDALVDFSEQYTPEADPYFIQDRFLNSFEELQAEECG----ILNG---C 1306
+ + + +D +Y P L E+ ++CG + +G
Sbjct: 1123 VDECASQPCQHGGSCIDLVARYLCSCPP-----GTLGVLCEINEDDCGPGPPLDSGPRCL 1177
Query: 1307 ENGRCVRVQEGYTCDCFDGYHLDTAKMTCVDVNECDELNNRMSLCKNA---KCI-NTDGS 1362
NG CV + G+ C C GY T D+NEC R C A C+ + G
Sbjct: 1178 HNGTCVDLVGGFRCTCPPGY---TGLRCEADINEC-----RSGACHAAHTRDCLQDPGGG 1229
Query: 1363 YKCLCLPGY 1371
++CLC G+
Sbjct: 1230 FRCLCHAGF 1238
Score = 207 bits (527), Expect = 6e-53
Identities = 278/1059 (26%), Positives = 387/1059 (36%), Gaps = 249/1059 (23%)
Query: 442 STHPPPLPAKEEPVEALTFSREHGPGVAEPEVATAPPEKEIPSLDQEKTKLEPGQPQLSP 501
S PPP P + P+ L GPG A P P LD G+ P
Sbjct: 16 SPPPPPPPVRALPLLLLLA----GPGAAAP-----------PCLDGSPCA-NGGRCTQLP 59
Query: 502 GISTIHLHPQFPGIVIEKTSPPVPVEVAPEASTSSA-SQVIAPTQVTEIN--------EC 552
L P PG V E+ P P A S V+A T +C
Sbjct: 60 SREAACLCP--PGWVGERCQLEDPCHSGPCAGRGVCQSSVVAGTARFSCRCPRGFRGPDC 117
Query: 553 TVNPDICGAGHC-------INLPVRYTCICYEGYRFSEQQRKC-VDIDECTQVQHLCSQG 604
++ PD C + C + R+ C C GY Q R C D+DEC + G
Sbjct: 118 SL-PDPCLSSPCAHGARCSVGPDGRFLCSCPPGY----QGRSCRSDVDECRVGEPCRHGG 172
Query: 605 RCENTEGSFLCICPAGF-----------------------------------MASEEGTN 629
C NT GSF C CPAG+ + EG N
Sbjct: 173 TCLNTPGSFRCQCPAGYTGPLCENPAVPCAPSPCRNGGTCRQSGDLTYDCACLPGFEGQN 232
Query: 630 C-IDVDECLRPDVCGEGHCVNTVGAFRCEYCDSGYRMTQRGRCEDIDEC-LNPSTCPD-E 686
C ++VD+C G CV+ V + C+ C + T + ED+DEC L P+ C +
Sbjct: 233 CEVNVDDCPGHRCLNGGTCVDGVNTYNCQ-CPPEW--TGQFCTEDVDECQLQPNACHNGG 289
Query: 687 QCVNSPGSYQCVPCTEGFRGWNGQCL--DVDECLEPNVCANG-DCSNLEGSYMCSCHKGY 743
C N+ G + CV C GW G+ ++D+C VC +G C + S+ C+C G
Sbjct: 290 TCFNTLGGHSCV-CV---NGWTGESCSQNIDDCATA-VCFHGATCHDRVASFYCACPMGK 344
Query: 744 TRTPDHKHCRDIDECQQGNLCVNGQCKNT---EGSFRCTCGQGYQLSAAKDQCEDIDECQ 800
T H +D+ N C +T G CTC G+ A +D+DEC
Sbjct: 345 TGLLCH-----LDDACVSNPCHEDAICDTNPVNGRAICTCPPGFTGGACD---QDVDECS 396
Query: 801 -HRHLCAH-GQCRNTEGSFQCVCDQGYRASGLGDHCE-DINECLEDKSVCQ-RGDCINTA 856
+ C H G+C NT+GSF C C +GY G CE D+NECL C+ + C++
Sbjct: 397 IGANPCEHLGRCVNTQGSFLCQCGRGY----TGPRCETDVNECL--SGPCRNQATCLDRI 450
Query: 857 GSYDCTCPDGFQLDDNKTCQ-DINECEHPGLCGPQGECLNTEGSFHCVCQQGFSISADGR 915
G + C C GF C+ DI+EC+ C G C + F C C GFS G
Sbjct: 451 GQFTCICMAGF---TGTYCEVDIDECQ-SSPCVNGGVCKDRVNGFSCTCPSGFS----GS 502
Query: 916 TCE-DIDECVNNTVCDSHGFCDNTAGSFRCLCYQGFQAPQDGQGCVDVNECELLSGVCGE 974
TC+ D+DEC +T C + C + + C C +GF +G C D N + C
Sbjct: 503 TCQLDVDECA-STPCRNGAKCVDQPDGYECRCAEGF----EGTLC-DRNVDDCSPDPCHH 556
Query: 975 AFCENVEGSFLCVCADENQEYSPMTGQCRSRTSTDLDVDVDQPKEEKKECYYNLNDASLC 1034
C + SF C CA G +R + +D QP +C L
Sbjct: 557 GRCVDGIASFSCACA---------PGYTGTRCESQVDECRSQPCRHGGKC------LDLV 601
Query: 1035 DNVLAPNVTKQECCCTSGAGWGDNCEI-------FPCPV----LGTAEFTEMCPKG---- 1079
D L C C SG G NCE+ PC G + +C G
Sbjct: 602 DKYL--------CRCPSGT-TGVNCEVNIDDCASNPCTFGVCRDGINRYDCVCQPGFTGP 652
Query: 1080 --------KGFVPAGESSSEAGGENYKDADECLL---------------FGQEICKNGFC 1116
P GE S GEN CL E C +G C
Sbjct: 653 LCNVEINECASSPCGEGGSCVDGEN---GFRCLCPPGSLPPLCLPPSHPCAHEPCSHGIC 709
Query: 1117 LNTRPGYECYCKQGTYYDPVKLQCFDMDECQDPSSCIDGQCVNTEGSYNCFCTHPMVLDA 1176
+ G+ C C+ G + P Q D C+ G C + ++C C P +
Sbjct: 710 YDAPGGFRCVCEPG-WSGPRCSQSLARDACESQPCRAGGTCSSDGMGFHCTC--PPGVQG 766
Query: 1177 SEKRCI-----RPAESNEQIEETDVYQDLC-----WEH---LSDEYVCSRPL------VG 1217
+ + P E + E +C W+ D C+ P +
Sbjct: 767 RQCELLSPCTPNPCEHGGRCESAPGQLPVCSCPQGWQGPRCQQDVDECAGPAPCGPHGIC 826
Query: 1218 KQTTYTECCCLYGEAWGMQCALCPLKDSDDYAQLCNIPVTGRRQPYGRDALVDFSEQYTP 1277
+ C +G G C +D +D C+ P +D + FS P
Sbjct: 827 TNLAGSFSCTCHGGYTGPSCD----QDIND----CD-PNPCLNGGSCQDGVGSFSCSCLP 877
Query: 1278 E-ADPYFIQDRFLNSFEELQAEECGILNGCENGRCVRVQEGYTCDC---FDGYHLDTAKM 1333
A P +D +EC + N C G C +TC C + G+H +
Sbjct: 878 GFAGPRCARD----------VDEC-LSNPCGPGTCTDHVASFTCTCPPGYGGFHCEQ--- 923
Query: 1334 TCVDVNECDELNNRMSLCKN-AKCINTDGSYKCLCLPGY 1371
D+ +C S C N C++ S+ CLC PGY
Sbjct: 924 ---DLPDCSP-----SSCFNGGTCVDGVNSFSCLCRPGY 954
Score = 169 bits (429), Expect = 1e-41
Identities = 204/808 (25%), Positives = 299/808 (37%), Gaps = 167/808 (20%)
Query: 271 CPKKPSYHGY------NQMMECLPGYKRVNNTFCQD-INECQLQGVCPNGECLNTMGSYR 323
C P +HG + C PGY T C+ ++EC+ Q G+CL+ + Y
Sbjct: 549 CSPDPCHHGRCVDGIASFSCACAPGY---TGTRCESQVDECRSQPCRHGGKCLDLVDKYL 605
Query: 324 CTCK---IGFGPDPTFSSCVPDPPVISEEKGPCYRLVSSGRQCMHPLSVHLTKQLCCCSV 380
C C G + C +P G C ++ P T LC +
Sbjct: 606 CRCPSGTTGVNCEVNIDDCASNPCTF----GVCRDGINRYDCVCQP---GFTGPLCNVEI 658
Query: 381 GKAWGPHCEK---CPLPGTAAFKEICPGGMGYTVSGVHRRRPIHHHVGKGPVFVKPKNTQ 437
+ C + C + G F+ +CP G + H G + P +
Sbjct: 659 NECASSPCGEGGSC-VDGENGFRCLCPPGSLPPLCLPPSHPCAHEPCSHGICYDAPGGFR 717
Query: 438 PVAKSTHPPPLPAKEEPVEALTFSREHGPGVAEPEV----ATAPPEKEIPSLDQEKTKLE 493
V + P ++ +A G + T PP + ++ L
Sbjct: 718 CVCEPGWSGPRCSQSLARDACESQPCRAGGTCSSDGMGFHCTCPPGVQ----GRQCELLS 773
Query: 494 PGQPQLSPGISTIHLHPQFPGIVIEKTSPPVPVEVAPEASTSSASQVIAPTQVTEINECT 553
P P +P G E +PV P+ Q +++EC
Sbjct: 774 PCTP-----------NPCEHGGRCESAPGQLPVCSCPQGWQGPRCQ-------QDVDECA 815
Query: 554 VNPDICGA-GHCINLPVRYTCICYEGYRFSEQQRKCVDIDECTQVQHLCSQGRCENTEGS 612
P CG G C NL ++C C+ GY + DI++C L + G C++ GS
Sbjct: 816 -GPAPCGPHGICTNLAGSFSCTCHGGYTGPSCDQ---DINDCDPNPCL-NGGSCQDGVGS 870
Query: 613 FLCICPAGFMASEEGTNCI-DVDECLRPDVCGEGHCVNTVGAFRCEYCDSGYRMTQRGRC 671
F C C GF G C DVDECL + CG G C + V +F C C GY C
Sbjct: 871 FSCSCLPGFA----GPRCARDVDECLS-NPCGPGTCTDHVASFTCT-CPPGYGGFH---C 921
Query: 672 E-DIDECLNPSTCPDE-QCVNSPGSYQCVPCTEGFRGWNGQCLDVDECLEPNVCANGDCS 729
E D+ +C +PS+C + CV+ S+ C+ C G+ G + Q + D CL G CS
Sbjct: 922 EQDLPDC-SPSSCFNGGTCVDGVNSFSCL-CRPGYTGAHCQH-EADPCLSRPCLHGGVCS 978
Query: 730 NLEGSYMCSCHKGYTRTP--------DHKHCRDIDECQQ------------GNLC----- 764
+ C+C + +T + C++ C Q G LC
Sbjct: 979 AAHPGFRCTCLESFTGPQCQTLVDWCSRQPCQNGGRCVQTGAYCLCPPGWSGRLCDIRSL 1038
Query: 765 ------------------VNGQCKNTEGSFRCTCGQGYQLSAAKDQCEDIDECQHRHLCA 806
GQC + + S C C +G S + +++D C +
Sbjct: 1039 PCREAAAQIGVRLEQLCQAGGQCVDEDSSHYCVCPEGRTGSHCE---QEVDPCLAQPCQH 1095
Query: 807 HGQCRNTEGSFQCVCDQGYRASGLGDHCED-INECLEDKSVCQRG-DCINTAGSYDCTCP 864
G CR G + C C GY GD+CED ++EC CQ G CI+ Y C+CP
Sbjct: 1096 GGTCRGYMGGYMCECLPGYN----GDNCEDDVDECASQP--CQHGGSCIDLVARYLCSCP 1149
Query: 865 DGFQLDDNKTCQDINECEHPGLCGP------------QGECLNTEGSFHCVCQQGFSISA 912
G C+ INE + CGP G C++ G F C C G++
Sbjct: 1150 PGTL---GVLCE-INEDD----CGPGPPLDSGPRCLHNGTCVDLVGGFRCTCPPGYT--- 1198
Query: 913 DGRTCE-DIDECVNNTVCDSH--GFCDNTAGSFRCLCYQGFQAPQ--------DGQGCVD 961
G CE DI+EC + +H + G FRCLC+ GF P+ + Q C
Sbjct: 1199 -GLRCEADINECRSGACHAAHTRDCLQDPGGGFRCLCHAGFSGPRCQTVLSPCESQPCQH 1257
Query: 962 VNECELLSGVCGEAFCENVEGSFLCVCA 989
+C G G +F C CA
Sbjct: 1258 GGQCRPSPGPGGGL-------TFTCHCA 1278
Score = 156 bits (395), Expect = 1e-37
Identities = 197/738 (26%), Positives = 288/738 (39%), Gaps = 132/738 (17%)
Query: 677 CLNPSTCPDE-QCVNSPGSYQCVPCTEGFRGWNGQCLDVDECLEPNVCANGDCSNL---- 731
CL+ S C + +C P C G+ G +C D C G C +
Sbjct: 43 CLDGSPCANGGRCTQLPSREAACLCPPGWVG--ERCQLEDPCHSGPCAGRGVCQSSVVAG 100
Query: 732 EGSYMCSCHKGYTRTPDHKHCRDIDECQQGNLCVNGQCK-NTEGSFRCTCGQGYQLSAAK 790
+ C C +G+ R PD C D C +C +G F C+C GYQ + +
Sbjct: 101 TARFSCRCPRGF-RGPD---CSLPDPCLSSPCAHGARCSVGPDGRFLCSCPPGYQGRSCR 156
Query: 791 DQCEDIDECQHRHLCAHG-QCRNTEGSFQCVCDQGYRASGLGDHCED-INECLEDKSVCQ 848
D+DEC+ C HG C NT GSF+C C GY G CE+ C S C+
Sbjct: 157 S---DVDECRVGEPCRHGGTCLNTPGSFRCQCPAGYT----GPLCENPAVPCAP--SPCR 207
Query: 849 RGDCINTAG--SYDCTCPDGFQLDDNKTCQDINECEHPG-LCGPQGECLNTEGSFHCVCQ 905
G +G +YDC C GF+ + C+ +N + PG C G C++ +++C C
Sbjct: 208 NGGTCRQSGDLTYDCACLPGFE---GQNCE-VNVDDCPGHRCLNGGTCVDGVNTYNCQCP 263
Query: 906 QGFSISADGRTC-EDIDEC-VNNTVCDSHGFCDNTAGSFRCLCYQGFQAPQDGQGCV-DV 962
++ G+ C ED+DEC + C + G C NT G C+C G+ G+ C ++
Sbjct: 264 PEWT----GQFCTEDVDECQLQPNACHNGGTCFNTLGGHSCVCVNGWT----GESCSQNI 315
Query: 963 NECELLSGVCGE-AFCENVEGSFLCVCADENQEYSPMTGQCRSRTSTDLDVDVDQPKEEK 1021
++C + VC A C + SF C C PM G+ D D V P E
Sbjct: 316 DDCA--TAVCFHGATCHDRVASFYCAC--------PM-GKTGLLCHLD-DACVSNPCHED 363
Query: 1022 KECYYN-LNDASLCDNVLAPNVTKQECC-----CTSGAGWGDNCEIFPCPVLGTAEFTE- 1074
C N +N ++C P T C C+ GA PC LG T+
Sbjct: 364 AICDTNPVNGRAIC--TCPPGFTGGACDQDVDECSIGAN--------PCEHLGRCVNTQG 413
Query: 1075 --MCPKGKGFVPAGESSSEAGGENYKDADECLLFGQEICKN-GFCLNTRPGYECYCKQG- 1130
+C G+G+ G D +ECL C+N CL+ + C C G
Sbjct: 414 SFLCQCGRGYT---------GPRCETDVNECL---SGPCRNQATCLDRIGQFTCICMAGF 461
Query: 1131 --TYYDPVKLQCFDMDECQDPSSCIDGQCVNTEGSYNCFCTHPMV-----LDASEKRCIR 1183
TY + D+DECQ G C + ++C C LD E
Sbjct: 462 TGTYCE------VDIDECQSSPCVNGGVCKDRVNGFSCTCPSGFSGSTCQLDVDECASTP 515
Query: 1184 PAESNEQIEETDVYQDLCWEHLSDEYVCSRPLVGKQTTYTECC----CLYGEAWGMQCAL 1239
+ +++ D Y+ C E +C R + + C C+ G A CA
Sbjct: 516 CRNGAKCVDQPDGYECRCAEGFEGT-LCDRNV---DDCSPDPCHHGRCVDGIA-SFSCAC 570
Query: 1240 CPLKDSDDYAQLCNIPVTG-RRQP--YGRDALVDFSEQYTPEADPYFIQDRFLNSFEELQ 1296
P C V R QP +G L D ++Y +N E+
Sbjct: 571 AP----GYTGTRCESQVDECRSQPCRHGGKCL-DLVDKYLCRCPS---GTTGVNC--EVN 620
Query: 1297 AEECGILNGCENGRCVRVQEGYTCDCFDGYHLDTAKMTCVDVNECDELNNRMSLC-KNAK 1355
++C N C G C Y C C G+ T + V++NEC S C +
Sbjct: 621 IDDCAS-NPCTFGVCRDGINRYDCVCQPGF---TGPLCNVEINECAS-----SPCGEGGS 671
Query: 1356 CINTDGSYKCLCLPGYVP 1373
C++ + ++CLC PG +P
Sbjct: 672 CVDGENGFRCLCPPGSLP 689
Score = 128 bits (322), Expect = 3e-29
Identities = 182/755 (24%), Positives = 244/755 (32%), Gaps = 164/755 (21%)
Query: 286 CLPGYKRVNNTFCQ-DINECQLQGVCPNGECLNTMGSYRCTCKIGFGPD---PTFSSCVP 341
C PG+ C +INEC G C++ +RC C G P P C
Sbjct: 645 CQPGF---TGPLCNVEINECASSPCGEGGSCVDGENGFRCLCPPGSLPPLCLPPSHPCAH 701
Query: 342 DPPVISEEKGPCYRLVSSGRQCMHPLSVHLTKQLCCCSVGKAWGPHCEK------CPLPG 395
+P G CY R C C G + GP C + C
Sbjct: 702 EPC----SHGICYDAPGGFR--------------CVCEPGWS-GPRCSQSLARDACESQP 742
Query: 396 TAAFKEICPGGMGYTVS---GVHRRR----------PIHHHVGKGPVFVKPKNTQPVAKS 442
A GMG+ + GV R+ P H G PV
Sbjct: 743 CRAGGTCSSDGMGFHCTCPPGVQGRQCELLSPCTPNPCEH----GGRCESAPGQLPVCSC 798
Query: 443 THPPPLPAKEEPVEALTFSREHGP-----GVAEPEVATAPPEKEIPSLDQEKTKLEPGQP 497
P ++ V+ GP +A T PS DQ+ +P P
Sbjct: 799 PQGWQGPRCQQDVDECAGPAPCGPHGICTNLAGSFSCTCHGGYTGPSCDQDINDCDPN-P 857
Query: 498 QLSPGISTIHLHPQFPGIVIEKTSPPVPVEVAPEASTSSASQVIAPTQVTEINECTVNPD 557
L+ G + S S P +++EC NP
Sbjct: 858 CLNGGSCQ---------------------DGVGSFSCSCLPGFAGPRCARDVDECLSNP- 895
Query: 558 ICGAGHCINLPVRYTCICYEGYRFSEQQRKCVDIDECTQVQHLCSQGRCENTEGSFLCIC 617
CG G C + +TC C GY ++ D+ +C+ + G C + SF C+C
Sbjct: 896 -CGPGTCTDHVASFTCTCPPGYGGFHCEQ---DLPDCSP-SSCFNGGTCVDGVNSFSCLC 950
Query: 618 PAGFMASE---EGTNCIDVDECLRPDVCGEGH------CVNTVGAFRCEY---------C 659
G+ + E C+ CL VC H C+ + +C+ C
Sbjct: 951 RPGYTGAHCQHEADPCLS-RPCLHGGVCSAAHPGFRCTCLESFTGPQCQTLVDWCSRQPC 1009
Query: 660 DSGYRMTQRGR-------------------CED----IDECLNPSTCPDEQCVNSPGSYQ 696
+G R Q G C + I L QCV+ S+
Sbjct: 1010 QNGGRCVQTGAYCLCPPGWSGRLCDIRSLPCREAAAQIGVRLEQLCQAGGQCVDEDSSHY 1069
Query: 697 CVPCTEGFRGWNGQCLDVDECLEPNVCANGDCSNLEGSYMCSCHKGYTRTPDHKHCR-DI 755
CV C EG G + + +VD CL G C G YMC C GY + +C D+
Sbjct: 1070 CV-CPEGRTGSHCE-QEVDPCLAQPCQHGGTCRGYMGGYMCECLPGY----NGDNCEDDV 1123
Query: 756 DECQQGNLCVNGQCKNTEGSFRCTCGQ---GYQLSAAKDQCEDIDECQHRHLCAH-GQCR 811
DEC G C + + C+C G +D C C H G C
Sbjct: 1124 DECASQPCQHGGSCIDLVARYLCSCPPGTLGVLCEINEDDCGPGPPLDSGPRCLHNGTCV 1183
Query: 812 NTEGSFQCVCDQGYRASGLGDHCE-DINECLEDK-SVCQRGDCI-NTAGSYDCTCPDGFQ 868
+ G F+C C GY G CE DINEC DC+ + G + C C GF
Sbjct: 1184 DLVGGFRCTCPPGY----TGLRCEADINECRSGACHAAHTRDCLQDPGGGFRCLCHAGF- 1238
Query: 869 LDDNKTCQDI------NECEHPGLC----GPQGECLNTEGSFHCVCQQGFSISADGRTCE 918
CQ + C+H G C GP G +F C C Q F G CE
Sbjct: 1239 --SGPRCQTVLSPCESQPCQHGGQCRPSPGPGGGL-----TFTCHCAQPFW----GPRCE 1287
Query: 919 DIDECVNNTVCDSHGFCDNTAGSFRCLCYQGFQAP 953
+ C C T RC C G P
Sbjct: 1288 RVARSCRELQCPVGVPCQQTPRGPRCACPPGLSGP 1322
Score = 50.4 bits (119), Expect = 1e-05
Identities = 42/151 (27%), Positives = 59/151 (39%), Gaps = 17/151 (11%)
Query: 269 QKCPKKPSYHGY--NQMMECLPGYKRVNNTFCQ-DINECQLQGVCPNGECLNTMGSYRCT 325
Q C + GY M ECLPGY N C+ D++EC Q G C++ + Y C+
Sbjct: 1091 QPCQHGGTCRGYMGGYMCECLPGY---NGDNCEDDVDECASQPCQHGGSCIDLVARYLCS 1147
Query: 326 C---KIGFGPDPTFSSCVPDPPVISEEK----GPCYRLVSSGRQCMHP---LSVHLTKQL 375
C +G + C P PP+ S + G C LV G +C P + +
Sbjct: 1148 CPPGTLGVLCEINEDDCGPGPPLDSGPRCLHNGTCVDLV-GGFRCTCPPGYTGLRCEADI 1206
Query: 376 CCCSVGKAWGPHCEKCPLPGTAAFKEICPGG 406
C G H C F+ +C G
Sbjct: 1207 NECRSGACHAAHTRDCLQDPGGGFRCLCHAG 1237
Score = 45.4 bits (106), Expect = 4e-04
Identities = 95/370 (25%), Positives = 136/370 (36%), Gaps = 83/370 (22%)
Query: 80 PCMNGGQCSSR-DK--CQCPPNFTGKLCQIPVHG-ASVP----------KLYQHSQQPGK 125
PC +GG+C DK C+CP TG C++ + AS P Y QPG
Sbjct: 590 PCRHGGKCLDLVDKYLCRCPSGTTGVNCEVNIDDCASNPCTFGVCRDGINRYDCVCQPGF 649
Query: 126 A--LGTHVIHSTHTLPL-----TVTSQQGVKVKFPPNIVN---IHVKHPPEASVQIHQVS 175
L I+ + P V + G + PP + + HP H +
Sbjct: 650 TGPLCNVEINECASSPCGEGGSCVDGENGFRCLCPPGSLPPLCLPPSHPCAHEPCSHGIC 709
Query: 176 RIDGPTGQKTKEAQPGQSQVSYQGLPVQKTQTIHSTYSHQQVIPHVYPVAAKTQLGRCFQ 235
D P G + +PG S + +Q++ Q P A G C
Sbjct: 710 -YDAPGGFRCV-CEPGWSGP-------RCSQSLARDACESQ------PCRAG---GTCSS 751
Query: 236 ETIGSQCGKALPGLSKQEDCCGTVGTSWGFNKCQKCPKKPSYHGYNQMMECLPGYKRVNN 295
+ +G C PG+ ++ C + N C+ + S G + C G++
Sbjct: 752 DGMGFHC-TCPPGVQGRQ--CELLSPCTP-NPCEHGGRCESAPGQLPVCSCPQGWQGPRC 807
Query: 296 TFCQDINECQLQGVC-PNGECLNTMGSYRCTCKIGF-GP--DPTFSSCVPDPPVISEEKG 351
QD++EC C P+G C N GS+ CTC G+ GP D + C P+P + G
Sbjct: 808 Q--QDVDECAGPAPCGPHGICTNLAGSFSCTCHGGYTGPSCDQDINDCDPNPCL---NGG 862
Query: 352 PCYRLVSSGRQCMHPLSVHLTKQLCCCSVGKAWGPHC----EKCPL----PGT-----AA 398
C V S C C G A GP C ++C PGT A+
Sbjct: 863 SCQDGVGSFS--------------CSCLPGFA-GPRCARDVDECLSNPCGPGTCTDHVAS 907
Query: 399 FKEICPGGMG 408
F CP G G
Sbjct: 908 FTCTCPPGYG 917
Score = 44.7 bits (104), Expect = 6e-04
Identities = 24/72 (33%), Positives = 35/72 (48%), Gaps = 3/72 (4%)
Query: 283 MMECLPGYKRVNNTFCQDINECQLQGVCPNG-ECLNTMGSYRCTCKIGFGPDPTFSSCVP 341
+ C PGY+ + D++EC++ C +G CLNT GS+RC C G+ + VP
Sbjct: 143 LCSCPPGYQ--GRSCRSDVDECRVGEPCRHGGTCLNTPGSFRCQCPAGYTGPLCENPAVP 200
Query: 342 DPPVISEEKGPC 353
P G C
Sbjct: 201 CAPSPCRNGGTC 212
Score = 42.0 bits (97), Expect = 0.004
Identities = 31/91 (34%), Positives = 41/91 (45%), Gaps = 21/91 (23%)
Query: 297 FC-QDINECQLQ-GVCPNG-ECLNTMGSYRCTCKIGFGPDPTFSSCVPDPPVISEEKGPC 353
FC +D++ECQLQ C NG C NT+G + C C G+ T SC S+ C
Sbjct: 270 FCTEDVDECQLQPNACHNGGTCFNTLGGHSCVCVNGW----TGESC-------SQNIDDC 318
Query: 354 YRLVSSGRQCMHPLSVH--LTKQLCCCSVGK 382
V C H + H + C C +GK
Sbjct: 319 ATAV-----CFHGATCHDRVASFYCACPMGK 344
Score = 38.1 bits (87), Expect = 0.060
Identities = 31/109 (28%), Positives = 47/109 (43%), Gaps = 22/109 (20%)
Query: 230 LGRCFQETIGS---QCGKALPGLSKQEDCCGTVGTSWGFNKCQKCPKKPSYHGYNQMME- 285
LGRC T GS QCG+ G + D N+C P + +++ +
Sbjct: 405 LGRCVN-TQGSFLCQCGRGYTGPRCETDV----------NECLSGPCRNQATCLDRIGQF 453
Query: 286 ---CLPGYKRVNNTFCQ-DINECQLQGVCPNGECLNTMGSYRCTCKIGF 330
C+ G+ T+C+ DI+ECQ G C + + + CTC GF
Sbjct: 454 TCICMAGF---TGTYCEVDIDECQSSPCVNGGVCKDRVNGFSCTCPSGF 499
Score = 37.0 bits (84), Expect = 0.13
Identities = 15/32 (46%), Positives = 18/32 (56%), Gaps = 3/32 (9%)
Query: 80 PCMNGGQCSSRDK---CQCPPNFTGKLCQIPV 108
PC+NGG C R C CP F+G CQ+ V
Sbjct: 477 PCVNGGVCKDRVNGFSCTCPSGFSGSTCQLDV 508
Score = 37.0 bits (84), Expect = 0.13
Identities = 14/28 (50%), Positives = 18/28 (64%), Gaps = 1/28 (3%)
Query: 80 PCMNGGQCSSRDK-CQCPPNFTGKLCQI 106
PC NGG+C C CPP ++G+LC I
Sbjct: 1008 PCQNGGRCVQTGAYCLCPPGWSGRLCDI 1035
Score = 36.2 bits (82), Expect = 0.23
Identities = 14/31 (45%), Positives = 19/31 (61%), Gaps = 3/31 (9%)
Query: 80 PCMNGGQCSSRD---KCQCPPNFTGKLCQIP 107
PC +GG C + +CQCP +TG LC+ P
Sbjct: 167 PCRHGGTCLNTPGSFRCQCPAGYTGPLCENP 197
Score = 35.8 bits (81), Expect = 0.30
Identities = 17/36 (47%), Positives = 23/36 (63%), Gaps = 6/36 (16%)
Query: 80 PCMNGGQCS---SRDK-CQCPPNFTGKLCQI--PVH 109
PC NGG+C+ SR+ C CPP + G+ CQ+ P H
Sbjct: 48 PCANGGRCTQLPSREAACLCPPGWVGERCQLEDPCH 83
Score = 34.7 bits (78), Expect = 0.66
Identities = 24/86 (27%), Positives = 36/86 (41%), Gaps = 14/86 (16%)
Query: 30 FTPSICK---VTCTKGSCQN--SCEKGNTTTLISENGHAADTLTATNFRVVICHLP---C 81
+T +C+ V C C+N +C + T + N V + P C
Sbjct: 189 YTGPLCENPAVPCAPSPCRNGGTCRQSGDLTY---DCACLPGFEGQNCEVNVDDCPGHRC 245
Query: 82 MNGGQCS---SRDKCQCPPNFTGKLC 104
+NGG C + CQCPP +TG+ C
Sbjct: 246 LNGGTCVDGVNTYNCQCPPEWTGQFC 271
Score = 33.5 bits (75), Expect = 1.5
Identities = 15/44 (34%), Positives = 22/44 (50%), Gaps = 4/44 (9%)
Query: 80 PCMNGGQCS----SRDKCQCPPNFTGKLCQIPVHGASVPKLYQH 119
PC +G +CS R C CPP + G+ C+ V V + +H
Sbjct: 127 PCAHGARCSVGPDGRFLCSCPPGYQGRSCRSDVDECRVGEPCRH 170
Score = 33.5 bits (75), Expect = 1.5
Identities = 24/97 (24%), Positives = 40/97 (41%), Gaps = 16/97 (16%)
Query: 286 CLPGYKRVNNTFCQ-DINECQLQGVCPNGECLNTMGSYRCTCKIGFGPDPTFSSCVPDPP 344
CLPG++ N C+ ++++C G C++ + +Y C C P+ T C D
Sbjct: 224 CLPGFEGQN---CEVNVDDCPGHRCLNGGTCVDGVNTYNCQCP----PEWTGQFCTEDVD 276
Query: 345 VISEEKGPCYRLVSSGRQCMHPLSVHLTKQLCCCSVG 381
+ C+ +G C + L H C C G
Sbjct: 277 ECQLQPNACH----NGGTCFNTLGGH----SCVCVNG 305
Score = 33.5 bits (75), Expect = 1.5
Identities = 36/139 (25%), Positives = 52/139 (37%), Gaps = 31/139 (22%)
Query: 231 GRCFQETIGSQCGKALPGLSKQEDCCGTVGTSWGFNKCQKCPKKPSY---HGYNQMMECL 287
G C Q+ +GS LPG + C V ++C P P H + C
Sbjct: 862 GSC-QDGVGSFSCSCLPGFAGPR-CARDV------DECLSNPCGPGTCTDHVASFTCTCP 913
Query: 288 PGYKRVNNTFC-QDINECQLQGVCPNGECLNTMGSYRCTCKIGFGPDPTFSSCVPDPPVI 346
PGY C QD+ +C G C++ + S+ C C+ G+ T + C
Sbjct: 914 PGY---GGFHCEQDLPDCSPSSCFNGGTCVDGVNSFSCLCRPGY----TGAHC------- 959
Query: 347 SEEKGPCYRLVSSGRQCMH 365
E PC R C+H
Sbjct: 960 QHEADPCL-----SRPCLH 973
Score = 33.5 bits (75), Expect = 1.5
Identities = 14/30 (46%), Positives = 17/30 (56%), Gaps = 3/30 (10%)
Query: 80 PCMNGGQCS---SRDKCQCPPNFTGKLCQI 106
PC +GG C +R C CPP G LC+I
Sbjct: 1130 PCQHGGSCIDLVARYLCSCPPGTLGVLCEI 1159
Score = 31.6 bits (70), Expect = 5.6
Identities = 24/77 (31%), Positives = 28/77 (36%), Gaps = 18/77 (23%)
Query: 38 TC--TKGSCQNSCEKGNTTTLISENGHAADTLTATNFRVVICHLPCMNGGQCSSRDK--- 92
TC T GS + C G T L N V PC NGG C
Sbjct: 173 TCLNTPGSFRCQCPAGYTGPLCE------------NPAVPCAPSPCRNGGTCRQSGDLTY 220
Query: 93 -CQCPPNFTGKLCQIPV 108
C C P F G+ C++ V
Sbjct: 221 DCACLPGFEGQNCEVNV 237
Score = 30.8 bits (68), Expect = 9.5
Identities = 17/51 (33%), Positives = 21/51 (41%), Gaps = 12/51 (23%)
Query: 75 VICHL-------PCMNGGQCSS-----RDKCQCPPNFTGKLCQIPVHGASV 113
++CHL PC C + R C CPP FTG C V S+
Sbjct: 347 LLCHLDDACVSNPCHEDAICDTNPVNGRAICTCPPGFTGGACDQDVDECSI 397
Score = 30.8 bits (68), Expect = 9.5
Identities = 15/52 (28%), Positives = 25/52 (48%), Gaps = 8/52 (15%)
Query: 80 PCMNGGQCSSRD-----KCQCPPNFTGKLCQIPVHGASVPKLYQHSQQPGKA 126
PC++GG C +C C +TG C+ P A+ P++ + + P A
Sbjct: 1343 PCLHGGSCRPAPLAPFFRCACAQGWTGPRCEAP---AAAPEVSEEPRCPRAA 1391
>gi|148833508 notch1 preproprotein [Homo sapiens]
Length = 2555
Score = 221 bits (564), Expect = 3e-57
Identities = 243/977 (24%), Positives = 367/977 (37%), Gaps = 246/977 (25%)
Query: 531 EASTSSASQVIAPTQVTEINECTVNPDICG-AGHCINLPVRYTCICYEGYRFSEQQRKCV 589
+A + S P +++EC++ + C AG CIN + C C +GY R +
Sbjct: 395 KAICTCPSGYTGPACSQDVDECSLGANPCEHAGKCINTLGSFECQCLQGY---TGPRCEI 451
Query: 590 DIDECTQVQHLC-SQGRCENTEGSFLCICPAGFMASEEGTNC-IDVDECLRPDVCGEGHC 647
D++EC V + C + C + G F CIC G+ EG +C ++ DEC G C
Sbjct: 452 DVNEC--VSNPCQNDATCLDQIGEFQCICMPGY----EGVHCEVNTDECASSPCLHNGRC 505
Query: 648 VNTVGAFRCEYCDSGYRMTQRGRCEDIDECLNPSTCPDEQCVNSPGSYQCVPCTEGFRGW 707
++ + F+CE C +G+ T D+DEC + +C++ P +Y CV CTEG+ G
Sbjct: 506 LDKINEFQCE-CPTGF--TGHLCQYDVDECASTPCKNGAKCLDGPNTYTCV-CTEGYTGT 561
Query: 708 NGQCLDVDECLEPNVCANGDCSNLEGSYMCSCHKGYTRTPDHKHCR-DIDECQQGNLCVN 766
+ + +D+DEC +P+ C G C + ++ C C GYT HC +I+EC
Sbjct: 562 HCE-VDIDEC-DPDPCHYGSCKDGVATFTCLCRPGYT----GHHCETNINECSSQPCRHG 615
Query: 767 GQCKNTEGSFRCTCGQGYQLSAAKDQCE-DIDECQHRHLCAHGQCRNTEGSFQCVCDQGY 825
G C++ + ++ C C +G CE ++D+C C G C + ++C C+ GY
Sbjct: 616 GTCQDRDNAYLCFCLKG----TTGPNCEINLDDCASSP-CDSGTCLDKIDGYECACEPGY 670
Query: 826 RASGL--------------GDHCED---------------------INECLEDKSVCQRG 850
S G CED +NEC + + C G
Sbjct: 671 TGSMCNINIDECAGNPCHNGGTCEDGINGFTCRCPEGYHDPTCLSEVNEC--NSNPCVHG 728
Query: 851 DCINTAGSYDCTCPDGFQLDDNKTCQ-DINECEHPGLCGPQGECLNTEGSFHCVCQQGFS 909
C ++ Y C C G+ C + NECE C G C + + C C++GFS
Sbjct: 729 ACRDSLNGYKCDCDPGW---SGTNCDINNNECE-SNPCVNGGTCKDMTSGYVCTCREGFS 784
Query: 910 ISADGRTCE-DIDECVNNTVCDSHGFC-DNTAG--------------------------- 940
G C+ +I+EC +N C + G C D+ AG
Sbjct: 785 ----GPNCQTNINECASNP-CLNQGTCIDDVAGYKCNCLLPYTGATCEVVLAPCAPSPCR 839
Query: 941 ------------SFRCLCYQGFQAPQDGQGC-VDVNECELLSGVCGEAFCENVEGSFLCV 987
SF C+C G+Q GQ C VD+NEC +LS A C+N G + C
Sbjct: 840 NGGECRQSEDYESFSCVCPTGWQ----GQTCEVDINEC-VLSPCRHGASCQNTHGGYRCH 894
Query: 988 CADENQEYSPMTGQCRSRTSTDLDVDVDQPKEEKKECYYNLNDASLCDNVLAPNVT---- 1043
C G TD+D P C +N A CD + T
Sbjct: 895 C---------QAGYSGRNCETDIDDCRPNPCHNGGSCTDGINTA-FCDCLPGFRGTFCEE 944
Query: 1044 -KQECC---CTSGAGWGDNCEIFPCPVLGTAEFTEMCPKGKGFVPAGESSSEAGGENYKD 1099
EC C +GA D + + C CP G + N D
Sbjct: 945 DINECASDPCRNGANCTDCVDSYTC----------TCPAGFSGIHC--------ENNTPD 986
Query: 1100 ADECLLFGQEICKNGFCLNTRPGYECYCKQGTYYDPVKLQCFDMDECQDPSSCIDGQCVN 1159
E F G C++ + C C G + D++EC G C +
Sbjct: 987 CTESSCF-----NGGTCVDGINSFTCLCPPGFTGSYCQ---HDVNECDSQPCLHGGTCQD 1038
Query: 1160 TEGSYNCFC----THPMVLDASEKRCIRPAESNEQIEETDVYQDLCWEHLSDEYVCSRPL 1215
GSY C C T P + P ++ + CW+ +Y C P
Sbjct: 1039 GCGSYRCTCPQGYTGPNCQNLVHWCDSSPCKNGGK----------CWQ-THTQYRCECP- 1086
Query: 1216 VGKQTTYTECCCLYGEAWGMQCALCPLKDSDDYAQLCNIPVTGRRQPYGRDALVDFSEQY 1275
+ LY + + C + + D A+LC +G VD +
Sbjct: 1087 -------SGWTGLYCDVPSVSCEVAAQRQGVDVARLCQ---------HG-GLCVDAGNTH 1129
Query: 1276 TPEADPYFIQDRFLNSFEELQAEECGILNGCENG-RCVRVQEGYTCDCFDGYH------- 1327
Q + S+ E +EC + C+NG C GY+C C GYH
Sbjct: 1130 HCRC-----QAGYTGSYCEDLVDECS-PSPCQNGATCTDYLGGYSCKCVAGYHGVNCSEE 1183
Query: 1328 ---------------LD---TAKMTC----------VDVNEC----DELNNRMSLCKNAK 1355
LD T K +C ++V++C D ++ N
Sbjct: 1184 IDECLSHPCQNGGTCLDLPNTYKCSCPRGTQGVHCEINVDDCNPPVDPVSRSPKCFNNGT 1243
Query: 1356 CINTDGSYKCLCLPGYV 1372
C++ G Y C C PG+V
Sbjct: 1244 CVDQVGGYSCTCPPGFV 1260
Score = 209 bits (531), Expect = 2e-53
Identities = 232/877 (26%), Positives = 345/877 (39%), Gaps = 147/877 (16%)
Query: 552 CTVNPDICGAG-HCINLPV--RYTCICYEGYRFSEQQRKCVDIDECTQVQHLCSQ-GRCE 607
C NP C G +C PV + C C GY + D+DEC+ + C G+C
Sbjct: 376 CISNP--CNEGSNCDTNPVNGKAICTCPSGYTGPACSQ---DVDECSLGANPCEHAGKCI 430
Query: 608 NTEGSFLCICPAGFMASEEGTNC-IDVDECLRPDVCGEGHCVNTVGAFRCEYCDSGYRMT 666
NT GSF C C G+ G C IDV+EC+ + C++ +G F+C C GY
Sbjct: 431 NTLGSFECQCLQGYT----GPRCEIDVNECVSNPCQNDATCLDQIGEFQC-ICMPGYEGV 485
Query: 667 QRGRCE-DIDECLNPSTCPDEQCVNSPGSYQCVPCTEGFRGWNGQCLDVDECLEPNVCAN 725
CE + DEC + + +C++ +QC C GF G Q DVDEC C N
Sbjct: 486 H---CEVNTDECASSPCLHNGRCLDKINEFQC-ECPTGFTGHLCQ-YDVDECAS-TPCKN 539
Query: 726 G-DCSNLEGSYMCSCHKGYTRTPDHKHCR-DIDECQQGNLCVNGQCKNTEGSFRCTCGQG 783
G C + +Y C C +GYT T HC DIDEC + C G CK+ +F C C G
Sbjct: 540 GAKCLDGPNTYTCVCTEGYTGT----HCEVDIDECDP-DPCHYGSCKDGVATFTCLCRPG 594
Query: 784 YQLSAAKDQCE-DIDECQHRHLCAHGQCRNTEGSFQCVCDQGYRASGLGDHCE-DINECL 841
Y CE +I+EC + G C++ + ++ C C +G G +CE ++++C
Sbjct: 595 Y----TGHHCETNINECSSQPCRHGGTCQDRDNAYLCFCLKGTT----GPNCEINLDDCA 646
Query: 842 EDKSVCQRGDCINTAGSYDCTCPDGFQLDDNKTCQ-DINECEHPGLCGPQGECLNTEGSF 900
S C G C++ Y+C C G+ C +I+EC C G C + F
Sbjct: 647 S--SPCDSGTCLDKIDGYECACEPGYT---GSMCNINIDECAG-NPCHNGGTCEDGINGF 700
Query: 901 HCVCQQGFSISADGRTCEDIDECVNNTVCDSHGFCDNTAGSFRCLCYQGFQAPQDGQGC- 959
C C +G+ D +++EC +N HG C ++ ++C C G+ G C
Sbjct: 701 TCRCPEGYH---DPTCLSEVNECNSNPCV--HGACRDSLNGYKCDCDPGWS----GTNCD 751
Query: 960 VDVNECELLSGVCGEAFCENVEGSFLCVCADENQEYSPMTG--QCRSRTSTDLDVDVDQP 1017
++ NECE V G C+++ ++C C + + T +C S + +D
Sbjct: 752 INNNECESNPCVNGGT-CKDMTSGYVCTCREGFSGPNCQTNINECASNPCLNQGTCIDDV 810
Query: 1018 KEEKKECYYNLNDASLCDNVLAPNVTKQECCCTSGAGWGDNC------EIFPCPVLGTAE 1071
K C A+ C+ VLAP C S G C E F C
Sbjct: 811 AGYKCNCLLPYTGAT-CEVVLAP-------CAPSPCRNGGECRQSEDYESFSC------- 855
Query: 1072 FTEMCPKGKGFVPAGESSSEAGGENYKDADECLLFGQEICKNGF-CLNTRPGYECYCKQG 1130
+CP G G D +EC+L C++G C NT GY C+C+ G
Sbjct: 856 ---VCPTGW-----------QGQTCEVDINECVL---SPCRHGASCQNTHGGYRCHCQAG 898
Query: 1131 TYYDPVKLQCFDMDECQDPSSCIDGQCVNTEGSYNCFCTHPMVLDASEKRCI---RPAES 1187
Y + D+D+C+ P+ C +G T+G FC C+ R
Sbjct: 899 --YSGRNCET-DIDDCR-PNPCHNGGSC-TDGINTAFCD-----------CLPGFRGTFC 942
Query: 1188 NEQIEETDVYQDLCWEHLS-----DEYVCSRPL-------VGKQTTYTECCCLYG----E 1231
E I E D C + D Y C+ P TE C G +
Sbjct: 943 EEDINECA--SDPCRNGANCTDCVDSYTCTCPAGFSGIHCENNTPDCTESSCFNGGTCVD 1000
Query: 1232 AWGMQCALCPLKDSDDYAQLCNIPVTGRRQPYGRDALVDFSEQYTPEADPYFIQDRFLNS 1291
LCP + Y Q + +G D Y + N
Sbjct: 1001 GINSFTCLCPPGFTGSYCQHDVNECDSQPCLHG-GTCQDGCGSYRCTCPQGYTGPNCQNL 1059
Query: 1292 FEELQAEECGILNGCENGRCVRVQEGYTCDC---FDGYHLDTAKMTCVDVNECDELNNRM 1348
+ C NG G+C + Y C+C + G + D ++C + ++
Sbjct: 1060 VHWCDSSPCK--NG---GKCWQTHTQYRCECPSGWTGLYCDVPSVSCEVAAQRQGVDVAR 1114
Query: 1349 SLCKNAKCINTDGSYKCLCLPGYVPS---DKPNYCTP 1382
C++ ++ C C GY S D + C+P
Sbjct: 1115 LCQHGGLCVDAGNTHHCRCQAGYTGSYCEDLVDECSP 1151
Score = 208 bits (529), Expect = 3e-53
Identities = 237/882 (26%), Positives = 345/882 (39%), Gaps = 182/882 (20%)
Query: 543 PTQVTEINECTVNPDIC-GAGHCINLPVRYTCICYEGYRFSEQQRKCVDIDECTQVQHLC 601
PT ++NEC P +C G C N Y C+C + +R V C
Sbjct: 173 PTCRQDVNECGQKPGLCRHGGTCHNEVGSYRCVCRATHTGPNCERPYVP----------C 222
Query: 602 SQGRCEN-------TEGSFLCICPAGFMASEEGTNCID-VDECLRPDVCGEGHCVNTVGA 653
S C+N + + C C GF G NC + +D+C + G CV+ V
Sbjct: 223 SPSPCQNGGTCRPTGDVTHECACLPGF----TGQNCEENIDDCPGNNCKNGGACVDGVNT 278
Query: 654 FRCEYCDSGYRMTQRGRCEDIDEC-LNPSTCPD-EQCVNSPGSYQCVPCTEGFRGWNGQ- 710
+ C C + T + ED+DEC L P+ C + C N+ G Y CV C GW G+
Sbjct: 279 YNCR-CPPEW--TGQYCTEDVDECQLMPNACQNGGTCHNTHGGYNCV-CV---NGWTGED 331
Query: 711 CLD-VDECLEPNVCANGDCSNLEGSYMCSCHKGYTRTPDHKHCRDI-DECQQGNLCVNGQ 768
C + +D+C C + S+ C C G T H + I + C +G+ C
Sbjct: 332 CSENIDDCASAACFHGATCHDRVASFYCECPHGRTGLLCHLNDACISNPCNEGSNC---D 388
Query: 769 CKNTEGSFRCTCGQGYQLSAAKDQCEDIDECQ-HRHLCAH-GQCRNTEGSFQCVCDQGYR 826
G CTC GY A +D+DEC + C H G+C NT GSF+C C QGY
Sbjct: 389 TNPVNGKAICTCPSGYTGPACS---QDVDECSLGANPCEHAGKCINTLGSFECQCLQGY- 444
Query: 827 ASGLGDHCE-DINECLEDKSVCQR-GDCINTAGSYDCTCPDGFQLDDNKTCQ-DINECEH 883
G CE D+NEC+ + CQ C++ G + C C G+ + C+ + +EC
Sbjct: 445 ---TGPRCEIDVNECVSNP--CQNDATCLDQIGEFQCICMPGY---EGVHCEVNTDECA- 495
Query: 884 PGLCGPQGECLNTEGSFHCVCQQGFSISADGRTCE-DIDECVNNTVCDSHGFCDNTAGSF 942
C G CL+ F C C GF+ G C+ D+DEC +T C + C + ++
Sbjct: 496 SSPCLHNGRCLDKINEFQCECPTGFT----GHLCQYDVDECA-STPCKNGAKCLDGPNTY 550
Query: 943 RCLCYQGFQAPQDGQGC-VDVNECELLSGVCGEAFCENVEGSFLCVCADENQEYSPMTGQ 1001
C+C +G+ G C VD++EC+ C C++ +F C+C G
Sbjct: 551 TCVCTEGY----TGTHCEVDIDECD--PDPCHYGSCKDGVATFTCLC---------RPGY 595
Query: 1002 CRSRTSTDLDVDVDQPKEEKKECYYNLNDASLCDNVLAPNVTKQECCCTSGAGWGDNCEI 1061
T+++ QP C + ++A L C C G G NCEI
Sbjct: 596 TGHHCETNINECSSQPCRHGGTC-QDRDNAYL-------------CFCLKGT-TGPNCEI 640
Query: 1062 FPCPVLGTAEFTEMC-PKGKGFVPAGESSSEAGGENYKDADECLLFGQEICKNGFCLNTR 1120
+ + C K G+ A E N + DEC G G C +
Sbjct: 641 NLDDCASSPCDSGTCLDKIDGYECACEPGYTGSMCNI-NIDECA--GNPCHNGGTCEDGI 697
Query: 1121 PGYECYCKQGTYYDPVKLQCFDMDECQDPSSCIDGQCVNTEGSYNCFCTHPMVLDASEKR 1180
G+ C C +G Y+DP L +++EC + + C+ G C ++ Y C C S
Sbjct: 698 NGFTCRCPEG-YHDPTCLS--EVNEC-NSNPCVHGACRDSLNGYKCDCDPGW----SGTN 749
Query: 1181 CIRPAESNEQIEETDVYQDLCWEHLSDEYVC------SRPLVGKQTTYTEC----CCLYG 1230
C +N + E + ++ YVC S P QT EC C G
Sbjct: 750 C---DINNNECESNPCVNGGTCKDMTSGYVCTCREGFSGP--NCQTNINECASNPCLNQG 804
Query: 1231 EAWGMQCALCPLKDSDDYAQLCNIPVTGRRQPYGRDALVDFSEQYTPEADPYFIQDRFLN 1290
+ D Y C +P TG
Sbjct: 805 TC---------IDDVAGYKCNCLLPYTG-------------------------------- 823
Query: 1291 SFEELQAEECGILNGCENGRCVRVQEGY---TCDCFDGYHLDTAKMTCVDVNECDELNNR 1347
+ E+ C + C NG R E Y +C C G+ T + VD+NEC
Sbjct: 824 ATCEVVLAPCA-PSPCRNGGECRQSEDYESFSCVCPTGWQGQTCE---VDINEC-----V 874
Query: 1348 MSLCKN-AKCINTDGSYKCLCLPGY--------VPSDKPNYC 1380
+S C++ A C NT G Y+C C GY + +PN C
Sbjct: 875 LSPCRHGASCQNTHGGYRCHCQAGYSGRNCETDIDDCRPNPC 916
Score = 187 bits (474), Expect = 8e-47
Identities = 224/847 (26%), Positives = 312/847 (36%), Gaps = 194/847 (22%)
Query: 594 CTQVQHLC-SQGRCENTEGSFLCICPAGFMASEEGTNCIDVDECLRPDVCGEGHC----V 648
C+Q C + G+CE G+ C+C F+ G C D + CL G C
Sbjct: 24 CSQPGETCLNGGKCEAANGTEACVCGGAFV----GPRCQDPNPCLSTPCKNAGTCHVVDR 79
Query: 649 NTVGAFRCEYCDSGYR----MTQRGRCEDIDECLNPSTCPDEQCVNSPGSYQCVPCTEGF 704
V + C C G+ +T + C N TC + + +C P
Sbjct: 80 RGVADYACS-CALGFSGPLCLTPLDNACLTNPCRNGGTC--DLLTLTEYKCRCPP----- 131
Query: 705 RGWNGQ-CLDVDECLEPNVCAN-GDCSNLEGSYMCSCHKGYTRTPDHKHCR-DIDEC-QQ 760
GW+G+ C D C N CAN G C E SY+C C + CR D++EC Q+
Sbjct: 132 -GWSGKSCQQADPCAS-NPCANGGQCLPFEASYICHCPPSF----HGPTCRQDVNECGQK 185
Query: 761 GNLCVN-GQCKNTEGSFRCTC------------------------GQGYQLSAAKDQC-- 793
LC + G C N GS+RC C G +C
Sbjct: 186 PGLCRHGGTCHNEVGSYRCVCRATHTGPNCERPYVPCSPSPCQNGGTCRPTGDVTHECAC 245
Query: 794 ----------EDIDECQHRHLCAHGQCRNTEGSFQCVCDQGYRASGLGDHC-EDINECLE 842
E+ID+C + G C + ++ C C + G +C ED++EC
Sbjct: 246 LPGFTGQNCEENIDDCPGNNCKNGGACVDGVNTYNCRCPPEW----TGQYCTEDVDECQL 301
Query: 843 DKSVCQR-GDCINTAGSYDCTCPDGFQLDDNKTCQDINECEHPGLCGPQGECLNTEGSFH 901
+ CQ G C NT G Y+C C +G+ +D ++I++C C C + SF+
Sbjct: 302 MPNACQNGGTCHNTHGGYNCVCVNGWTGED--CSENIDDCA-SAACFHGATCHDRVASFY 358
Query: 902 CVCQQGFSISADGRTCEDIDECVNNTVCDSHGFCDNTA--GSFRCLCYQGFQAPQDGQGC 959
C C G G C D C++N C+ CD G C C G+ P Q
Sbjct: 359 CECPHG----RTGLLCHLNDACISNP-CNEGSNCDTNPVNGKAICTCPSGYTGPACSQ-- 411
Query: 960 VDVNECELLSGVCGEA-FCENVEGSFLCVCADENQEYSPMTGQCRSRTSTDLDVDVDQPK 1018
DV+EC L + C A C N GSF C C + G R D++ V P
Sbjct: 412 -DVDECSLGANPCEHAGKCINTLGSFECQC---------LQGYTGPRCEIDVNECVSNPC 461
Query: 1019 EEKKECYYNLNDASLCDNVLAPNVTKQECCCTSGAGW------GDNCEIFPCPVLGTA-- 1070
+ NDA+ D + + +C C G D C PC G
Sbjct: 462 Q---------NDATCLD-----QIGEFQCICMPGYEGVHCEVNTDECASSPCLHNGRCLD 507
Query: 1071 ---EFTEMCPKGKGFVPAGESSSEAGGENYKDADECLLFGQEICKNGF-CLNTRPGYECY 1126
EF CP G G D DEC CKNG CL+ Y C
Sbjct: 508 KINEFQCECPTG-----------FTGHLCQYDVDEC---ASTPCKNGAKCLDGPNTYTCV 553
Query: 1127 CKQGTYYDPVKLQCFDMDECQDPSSCIDGQCVNTEGSYNCFCTHPMVLDASEKRCIRPAE 1186
C +G Y + D+DEC DP C G C + ++ C C RP
Sbjct: 554 CTEG--YTGTHCE-VDIDEC-DPDPCHYGSCKDGVATFTCLC--------------RPGY 595
Query: 1187 SNEQIEETDVYQDLCWEHLSDEYVCSRPLVGKQTTYTECCCLYGEAWGMQCALCPLKDSD 1246
+ ET++ E S + Y C CL G G C + + D
Sbjct: 596 TGHHC-ETNIN-----ECSSQPCRHGGTCQDRDNAYL-CFCLKGTT-GPNCEI----NLD 643
Query: 1247 DYAQLCNIPVTGRRQPYGRDALVDFSEQYTPEADPYFIQDRFLNSFEELQAEECGILNGC 1306
D A P +D + Y +P + S + +EC N C
Sbjct: 644 DCAS----------SPCDSGTCLDKIDGYECACEP-----GYTGSMCNINIDECA-GNPC 687
Query: 1307 EN-GRCVRVQEGYTCDCFDGYHLDTAKMTCV-DVNECDELNNRMSLCKNAKCINTDGSYK 1364
N G C G+TC C +GYH TC+ +VNEC+ + C + C ++ YK
Sbjct: 688 HNGGTCEDGINGFTCRCPEGYH----DPTCLSEVNECNS-----NPCVHGACRDSLNGYK 738
Query: 1365 CLCLPGY 1371
C C PG+
Sbjct: 739 CDCDPGW 745
Score = 174 bits (440), Expect = 7e-43
Identities = 214/823 (26%), Positives = 308/823 (37%), Gaps = 147/823 (17%)
Query: 595 TQVQHLCSQGRCEN-------TEGSFLCICPAGFMASEEGTNCIDVDECLRPDVCGEGHC 647
T + + C C N T + C CP G+ G +C D C G C
Sbjct: 100 TPLDNACLTNPCRNGGTCDLLTLTEYKCRCPPGW----SGKSCQQADPCASNPCANGGQC 155
Query: 648 VNTVGAFRCEYCDSGYRMTQRGRCEDIDEC-LNPSTCPDE-QCVNSPGSYQCVPCTEGFR 705
+ ++ C S + T R +D++EC P C C N GSY+CV C
Sbjct: 156 LPFEASYICHCPPSFHGPTCR---QDVNECGQKPGLCRHGGTCHNEVGSYRCV-CRATHT 211
Query: 706 GWNGQCLDVDECLEPNVCANGDCSNLEG--SYMCSCHKGYTRTPDHKHCRD-IDECQQGN 762
G N C P+ C NG G ++ C+C G+T ++C + ID+C GN
Sbjct: 212 GPN--CERPYVPCSPSPCQNGGTCRPTGDVTHECACLPGFTG----QNCEENIDDCP-GN 264
Query: 763 LCVNG-QCKNTEGSFRCTCGQGYQLSAAKDQCEDIDECQHR-HLCAHG-QCRNTEGSFQC 819
C NG C + ++ C C + + ED+DECQ + C +G C NT G + C
Sbjct: 265 NCKNGGACVDGVNTYNCRCPPEW---TGQYCTEDVDECQLMPNACQNGGTCHNTHGGYNC 321
Query: 820 VCDQGYRASGLGDHC-EDINECLEDKSVCQRG-DCINTAGSYDCTCPDG---FQLDDNKT 874
VC G+ G+ C E+I++C + C G C + S+ C CP G N
Sbjct: 322 VCVNGWT----GEDCSENIDDCAS--AACFHGATCHDRVASFYCECPHGRTGLLCHLNDA 375
Query: 875 CQDINECEHPGLCGPQGECLNTEGSFHCVCQQGFSISADGRTC-EDIDEC-VNNTVCDSH 932
C N C C G C C G++ G C +D+DEC + C+
Sbjct: 376 CIS-NPCNEGSNCDTNP----VNGKAICTCPSGYT----GPACSQDVDECSLGANPCEHA 426
Query: 933 GFCDNTAGSFRCLCYQGFQAPQDGQGC-VDVNECELLSGVC-GEAFCENVEGSFLCVCAD 990
G C NT GSF C C QG+ P+ C +DVNEC +S C +A C + G F C+C
Sbjct: 427 GKCINTLGSFECQCLQGYTGPR----CEIDVNEC--VSNPCQNDATCLDQIGEFQCICMP 480
Query: 991 --ENQEYSPMTGQCRSRTSTDLDVDVDQPKEEKKECYYNLNDASLCDNVLAPNVTKQECC 1048
E T +C S +D+ E + EC LC EC
Sbjct: 481 GYEGVHCEVNTDECASSPCLHNGRCLDKINEFQCECPTGFT-GHLC------QYDVDECA 533
Query: 1049 ---CTSGAGWGDNCEIFPCPVLGTAEFTEMCPKGKGFVPAGESSSEAGGENYKDADECLL 1105
C +GA D + C +C +G G D DEC
Sbjct: 534 STPCKNGAKCLDGPNTYTC----------VCTEG-----------YTGTHCEVDIDEC-- 570
Query: 1106 FGQEICKNGFCLNTRPGYECYCKQGTYYDPVKLQCFDMDECQDPSSCIDGQCVNTEGSYN 1165
+ C G C + + C C+ G + +++EC G C + + +Y
Sbjct: 571 -DPDPCHYGSCKDGVATFTCLCRPGYTGHHCET---NINECSSQPCRHGGTCQDRDNAYL 626
Query: 1166 CFC----THPMVLDASEKRCIRPAESNEQIEETDVYQDLCWEHLSDEYVCSRPLVGKQTT 1221
CFC T P + P +S +++ D Y+ C + +C+
Sbjct: 627 CFCLKGTTGPNCEINLDDCASSPCDSGTCLDKIDGYECACEPGYTGS-MCN-------IN 678
Query: 1222 YTECC---CLYGEAW-----GMQCALCPLKDSD----DYAQLCNIPVTGRRQPYGRDALV 1269
EC C G G C CP D CN P A
Sbjct: 679 IDECAGNPCHNGGTCEDGINGFTCR-CPEGYHDPTCLSEVNECN------SNPCVHGACR 731
Query: 1270 DFSEQYTPEADPYFIQDRFLNSFEELQAEECGILNGCENGRCVRVQEGYTCDCFDGYHLD 1329
D Y + DP + + E ++ C +NG G C + GY C C +G+
Sbjct: 732 DSLNGYKCDCDPGWSGTNCDINNNECESNPC--VNG---GTCKDMTSGYVCTCREGFSGP 786
Query: 1330 TAKMTCVDVNECDELNNRMSLCKN-AKCINTDGSYKCLCLPGY 1371
+ ++NEC + C N CI+ YKC CL Y
Sbjct: 787 NCQ---TNINEC-----ASNPCLNQGTCIDDVAGYKCNCLLPY 821
Score = 165 bits (417), Expect = 3e-40
Identities = 181/654 (27%), Positives = 270/654 (41%), Gaps = 121/654 (18%)
Query: 571 YTCICYEGYRFSEQQRKC-VDIDECTQVQHLCSQGR-CENTEGSFLCICPAGFMASEEGT 628
++C+C G+ Q + C VDI+EC V C G C+NT G + C C AG+ G
Sbjct: 853 FSCVCPTGW----QGQTCEVDINEC--VLSPCRHGASCQNTHGGYRCHCQAGY----SGR 902
Query: 629 NC-IDVDECLRPDVCGEG-HCVNTVGAFRCEYCDSGYRMTQRGRCE-DIDECLNPSTCPD 685
NC D+D+C RP+ C G C + + C+ C G+R T CE DI+EC +
Sbjct: 903 NCETDIDDC-RPNPCHNGGSCTDGINTAFCD-CLPGFRGTF---CEEDINECASDPCRNG 957
Query: 686 EQCVNSPGSYQCVPCTEGFRGWNGQCLDVDECLEPNVCANGDCSNLEGSYMCSCHKGYTR 745
C + SY C C GF G + + + +C E + G C + S+ C C G+T
Sbjct: 958 ANCTDCVDSYTCT-CPAGFSGIHCEN-NTPDCTESSCFNGGTCVDGINSFTCLCPPGFTG 1015
Query: 746 TPDHKHCR-DIDECQQGNLCVNGQCKNTEGSFRCTCGQGYQLSAAKDQCEDIDECQHRHL 804
+ +C+ D++EC G C++ GS+RCTC QGY C+++
Sbjct: 1016 S----YCQHDVNECDSQPCLHGGTCQDGCGSYRCTCPQGY----TGPNCQNLVHWCDSSP 1067
Query: 805 CAH-GQCRNTEGSFQCVCDQGYRASGL-----GDHCEDI--NECLEDKSVCQRGD-CINT 855
C + G+C T ++C C G+ +GL CE + ++ +CQ G C++
Sbjct: 1068 CKNGGKCWQTHTQYRCECPSGW--TGLYCDVPSVSCEVAAQRQGVDVARLCQHGGLCVDA 1125
Query: 856 AGSYDCTCPDGFQLDDNKTCQD-INECEHPGLCGPQGECLNTEGSFHCVCQQGFSISADG 914
++ C C G+ C+D ++EC P C C + G + C C G+ G
Sbjct: 1126 GNTHHCRCQAGY---TGSYCEDLVDECS-PSPCQNGATCTDYLGGYSCKCVAGY----HG 1177
Query: 915 RTC-EDIDECVNNTVCDSHGFCDNTAGSFRCLCYQGFQAPQDGQGC-VDVNECE------ 966
C E+IDEC+++ C + G C + +++C C +G Q G C ++V++C
Sbjct: 1178 VNCSEEIDECLSHP-CQNGGTCLDLPNTYKCSCPRGTQ----GVHCEINVDDCNPPVDPV 1232
Query: 967 LLSGVC-GEAFCENVEGSFLCVCADENQEYSPMTGQCRSRTSTDLDVDVDQPKEEKKECY 1025
S C C + G + C C G R D++ EC
Sbjct: 1233 SRSPKCFNNGTCVDQVGGYSCTCP---------PGFVGERCEGDVN-----------ECL 1272
Query: 1026 YNLNDASLCDNVLAPNVTKQECCCTSGAGWGDNCEIF-------PCPVLGTAEFTEMCPK 1078
N DA N + V C C +G G CE PC GT
Sbjct: 1273 SNPCDARGTQNCV-QRVNDFHCECRAG-HTGRRCESVINGCKGKPCKNGGTCAVAS--NT 1328
Query: 1079 GKGFV---PAGESSSEAGGENYKDADECLLFGQEICKN-GFCLNTRPGYECYCKQGTYYD 1134
+GF+ PAG G DA C G C N G C++ C C
Sbjct: 1329 ARGFICKCPAGFE----GATCENDARTC---GSLRCLNGGTCISGPRSPTCLC------- 1374
Query: 1135 PVKLQCFDMDECQDPSSCIDGQCVNTEGSYNCFCTHPMVLDASEKRCIRPAESN 1188
L F ECQ P+S C+ YN P ++ RC+ PA+ N
Sbjct: 1375 ---LGPFTGPECQFPAS---SPCLGGNPCYNQGTCEP-TSESPFYRCLCPAKFN 1421
Score = 162 bits (411), Expect = 2e-39
Identities = 189/750 (25%), Positives = 278/750 (37%), Gaps = 144/750 (19%)
Query: 670 RCEDIDE-CLNPSTCPDEQCVNSPGSYQCVPCTEGFRGWNGQCLDVDECLEPNVCANGDC 728
RC E CLN C + N G+ CV C F G C +PN C + C
Sbjct: 23 RCSQPGETCLNGGKC---EAAN--GTEACV-CGGAFVG--------PRCQDPNPCLSTPC 68
Query: 729 SNLE----------GSYMCSCHKGYTR----TPDHKHCRDIDECQQGNLCVNGQCKNTEG 774
N Y CSC G++ TP C + C+ G C T
Sbjct: 69 KNAGTCHVVDRRGVADYACSCALGFSGPLCLTPLDNACLT-NPCRNGGTCD----LLTLT 123
Query: 775 SFRCTCGQGYQLSAAKDQCEDIDECQHRHLCAHGQCRNTEGSFQCVCDQGYRASGLGDHC 834
++C C G+ + C+ D C GQC E S+ C C + G C
Sbjct: 124 EYKCRCPPGW----SGKSCQQADPCASNPCANGGQCLPFEASYICHCPPSFH----GPTC 175
Query: 835 -EDINECLEDKSVCQRGD-CINTAGSYDCTCP---DGFQLDDNKTCQDINECEHPGLCGP 889
+D+NEC + +C+ G C N GSY C C G + + C++ G C P
Sbjct: 176 RQDVNECGQKPGLCRHGGTCHNEVGSYRCVCRATHTGPNCERPYVPCSPSPCQNGGTCRP 235
Query: 890 QGECLNTEGSFHCVCQQGFSISADGRTCED-IDECVNNTVCDSHGFCDNTAGSFRCLCYQ 948
G+ + C C GF+ G+ CE+ ID+C N C + G C + ++ C C
Sbjct: 236 TGDVTH-----ECACLPGFT----GQNCEENIDDCPGNN-CKNGGACVDGVNTYNCRCPP 285
Query: 949 GFQAPQDGQGCV-DVNECELLSGVCGEA-FCENVEGSFLCVCAD--ENQEYSPMTGQCRS 1004
+ GQ C DV+EC+L+ C C N G + CVC + ++ S C S
Sbjct: 286 EWT----GQYCTEDVDECQLMPNACQNGGTCHNTHGGYNCVCVNGWTGEDCSENIDDCAS 341
Query: 1005 RTSTDLDVDVDQPKEEKKECYYNLNDASLCDNVLAPNVTKQECCCTSGAGWGDNCEIFPC 1064
D+ EC + LC + C ++ G NC+ P
Sbjct: 342 AACFHGATCHDRVASFYCECPHG-RTGLLCH--------LNDACISNPCNEGSNCDTNP- 391
Query: 1065 PVLGTAEFTEMCPKGKGFVPAGESSSEAGGENYKDADECLLFGQEICKN-GFCLNTRPGY 1123
V G A T CP G G + S+ D DEC L G C++ G C+NT +
Sbjct: 392 -VNGKAICT--CPSGY----TGPACSQ-------DVDECSL-GANPCEHAGKCINTLGSF 436
Query: 1124 ECYCKQGTYYDPVKLQC-FDMDECQDPSSCIDGQCVNTEGSYNCFCTHPMVLDASEKRCI 1182
EC C QG Y P +C D++EC D C++ G + C C + C
Sbjct: 437 ECQCLQG-YTGP---RCEIDVNECVSNPCQNDATCLDQIGEFQCIC----MPGYEGVHC- 487
Query: 1183 RPAESNEQIEETDVYQDLCWEHLSDEYVCSRPLVGKQTTYTECCCLYGEAWGMQCALCPL 1242
++E ++ C + ++ E+ C P T +T C Y +CA P
Sbjct: 488 -EVNTDECASSPCLHNGRCLDKIN-EFQCECP-----TGFTGHLCQYDVD---ECASTPC 537
Query: 1243 KDS-------DDYAQLCNIPVTGRR----------QPYGRDALVDFSEQYTPEADPYFIQ 1285
K+ + Y +C TG P + D +T P +
Sbjct: 538 KNGAKCLDGPNTYTCVCTEGYTGTHCEVDIDECDPDPCHYGSCKDGVATFTCLCRPGYTG 597
Query: 1286 DRFLNSFEELQAEECGILNGCENGRCVRVQEGYTCDCFDGYHLDTAKMTC-VDVNECDEL 1344
+ E ++ C G C Y C C G T C +++++C
Sbjct: 598 HHCETNINECSSQPCR-----HGGTCQDRDNAYLCFCLKG----TTGPNCEINLDDCAS- 647
Query: 1345 NNRMSLCKNAKCINTDGSYKCLCLPGYVPS 1374
S C + C++ Y+C C PGY S
Sbjct: 648 ----SPCDSGTCLDKIDGYECACEPGYTGS 673
Score = 68.2 bits (165), Expect = 5e-11
Identities = 155/661 (23%), Positives = 215/661 (32%), Gaps = 170/661 (25%)
Query: 286 CLPGYKRVNNTFCQ-DINECQLQGVCPNGECLNTMGSYRCTCKIGFGPDPTFSSCVPDPP 344
C PG+ ++CQ D+NEC Q G C + GSYRCTC G+
Sbjct: 1009 CPPGF---TGSYCQHDVNECDSQPCLHGGTCQDGCGSYRCTCPQGY-------------- 1051
Query: 345 VISEEKGPCYRLVSSGRQCMHPLSVHLTKQLCCCSVGKAWGPHCE---KCPLPGTAAFKE 401
+G C + VH C + GK W H + +CP T + +
Sbjct: 1052 --------------TGPNCQN--LVHWCDSSPCKNGGKCWQTHTQYRCECPSGWTGLYCD 1095
Query: 402 ICPGGMGYTVSGVHRRRPIHHHVGKGPVFVKPKNT--------------QPVAKSTHPPP 447
+ + V+ + + G + V NT + + P P
Sbjct: 1096 V--PSVSCEVAAQRQGVDVARLCQHGGLCVDAGNTHHCRCQAGYTGSYCEDLVDECSPSP 1153
Query: 448 LPAKEEPVEAL------TFSREHGPGVAE--PEVATAPPEKEIPSLDQEKTKLEPGQPQL 499
+ L + HG +E E + P + LD T +
Sbjct: 1154 CQNGATCTDYLGGYSCKCVAGYHGVNCSEEIDECLSHPCQNGGTCLDLPNTY----KCSC 1209
Query: 500 SPGISTIHLHPQFPGIVIEKTSPPV-PVEVAPEASTSSA--------SQVIAPTQVTE-- 548
G +H I ++ +PPV PV +P+ + S P V E
Sbjct: 1210 PRGTQGVHCE-----INVDDCNPPVDPVSRSPKCFNNGTCVDQVGGYSCTCPPGFVGERC 1264
Query: 549 ---INECTVNP-DICGAGHCINLPVRYTCICYEGYRFSEQQRKCVDIDECTQVQHLCSQG 604
+NEC NP D G +C+ + C C G+ R+C + + + + G
Sbjct: 1265 EGDVNECLSNPCDARGTQNCVQRVNDFHCECRAGH----TGRRCESVINGCKGKPCKNGG 1320
Query: 605 RC---ENTEGSFLCICPAGFMASEEGTNCIDVDECLRPDVCGEGHCVNTVGAFRCEYCDS 661
C NT F+C CPAGF EG C + T G+ R
Sbjct: 1321 TCAVASNTARGFICKCPAGF----EGATC--------------ENDARTCGSLR------ 1356
Query: 662 GYRMTQRGRCEDIDECLNPSTCPDEQCVNSPGSYQCVPCTEGFRGWNGQCLDVDECLEPN 721
CLN T C++ P S C+ C F G Q CL N
Sbjct: 1357 ---------------CLNGGT-----CISGPRSPTCL-CLGPFTGPECQFPASSPCLGGN 1395
Query: 722 VCAN-GDCSNLEGS--YMCSCHKGYTRTPDH--------KHCRDIDECQQGNLCVNGQCK 770
C N G C S Y C C + H RDI C +C+
Sbjct: 1396 PCYNQGTCEPTSESPFYRCLCPAKFNGLLCHILDYSFGGGAGRDIPPPLIEEACELPECQ 1455
Query: 771 NTEGSFRCTCGQGYQLSAAKDQCE-DIDECQHRHLCAHGQCRNTEGSFQCVCDQGYRASG 829
G+ C+ L C D +C L + +N S QC Y + G
Sbjct: 1456 EDAGNKVCS------LQCNNHACGWDGGDCS---LNFNDPWKNCTQSLQC---WKYFSDG 1503
Query: 830 LGDHCEDINECLEDKSVCQR--GDCINTAGSYDCTCPDGFQLDDNKTCQDIN--ECEHPG 885
D + CL D CQR G C YD C D F D Q N ECE G
Sbjct: 1504 HCDSQCNSAGCLFDGFDCQRAEGQC---NPLYDQYCKDHF--SDGHCDQGCNSAECEWDG 1558
Query: 886 L 886
L
Sbjct: 1559 L 1559
Score = 50.8 bits (120), Expect = 9e-06
Identities = 85/344 (24%), Positives = 126/344 (36%), Gaps = 61/344 (17%)
Query: 80 PCMNGGQCS----SRDKCQCPPNFTGKLCQIPVHGASVPKLYQHSQQPGKALGTHVIHST 135
PC NGG C + KC+CPP ++GK CQ AS P G+ L +
Sbjct: 110 PCRNGGTCDLLTLTEYKCRCPPGWSGKSCQQADPCASNP-----CANGGQCLPFEASYIC 164
Query: 136 HTLPLTVTSQQGVKVKFPPNIVNIHVKHPPEASVQIHQVSRIDGPTGQKTKEAQPGQSQV 195
H PP+ H P +++ GQK + G +
Sbjct: 165 HC---------------PPSF------HGPTCRQDVNEC-------GQKPGLCRHGGTCH 196
Query: 196 SYQGLPVQKTQTIHSTYSHQQVIPHVYPVAAKTQLGRCFQET--IGSQCGKALPGLSKQE 253
+ G + H+ + ++ P+V + Q G + T + +C LPG + Q
Sbjct: 197 NEVGSYRCVCRATHTGPNCER--PYVPCSPSPCQNGGTCRPTGDVTHECA-CLPGFTGQ- 252
Query: 254 DCCGTVGTSWGFNKCQKCPKKPSYHGYNQMMECLPGYKRVNNTFC-QDINECQLQ-GVCP 311
+C + G N + YN C P + +C +D++ECQL C
Sbjct: 253 NCEENIDDCPGNNCKNGGACVDGVNTYN--CRCPPEW---TGQYCTEDVDECQLMPNACQ 307
Query: 312 NG-ECLNTMGSYRCTCKIGFGPDPTFSSCVPDPPVISEEKGPCY-RLVSSGRQCMH---P 366
NG C NT G Y C C G+ + + C+ R+ S +C H
Sbjct: 308 NGGTCHNTHGGYNCVCVNGWTGEDCSENIDDCASAACFHGATCHDRVASFYCECPHGRTG 367
Query: 367 LSVHLTKQLCCCSVGKAWGPHCEKCPLPGTAAFKEICPGGMGYT 410
L HL C S G +C+ P+ G K IC GYT
Sbjct: 368 LLCHLND--ACISNPCNEGSNCDTNPVNG----KAICTCPSGYT 405
Score = 47.4 bits (111), Expect = 1e-04
Identities = 29/65 (44%), Positives = 35/65 (53%), Gaps = 14/65 (21%)
Query: 285 ECLPGYKRVNNTFCQ-DINECQLQGVCPNG-ECLNTMGSYRCTCKIGFG--------PDP 334
+CLPG++ TFC+ DINEC C NG C + + SY CTC GF PD
Sbjct: 932 DCLPGFR---GTFCEEDINECA-SDPCRNGANCTDCVDSYTCTCPAGFSGIHCENNTPDC 987
Query: 335 TFSSC 339
T SSC
Sbjct: 988 TESSC 992
Score = 43.9 bits (102), Expect = 0.001
Identities = 76/321 (23%), Positives = 116/321 (36%), Gaps = 67/321 (20%)
Query: 80 PCMNGGQCSSRDK---CQCPPNFTGKLCQIPVHG-ASVPKLYQHSQQPGKALGTH--VIH 133
PC NGGQC + C CPP+F G C+ V+ P L +H +G++ V
Sbjct: 148 PCANGGQCLPFEASYICHCPPSFHGPTCRQDVNECGQKPGLCRHGGTCHNEVGSYRCVCR 207
Query: 134 STHTLPLTVTSQQGVKVKFPPNIVNIHVKHPPEASVQIHQVSRIDGPTGQKTKE---AQP 190
+THT P + + V P+ P V H+ + + G TGQ +E P
Sbjct: 208 ATHTGP----NCERPYVPCSPSPCQNGGTCRPTGDV-THECACLPGFTGQNCEENIDDCP 262
Query: 191 GQSQVSYQGLPVQKTQTIHSTYSHQQVIPHVYPVAAKTQLGRCFQETIGSQCGKALPGLS 250
G + G V T + RC E G C + +
Sbjct: 263 G-NNCKNGGACVDGVNTYNC---------------------RCPPEWTGQYCTEDVDECQ 300
Query: 251 KQEDCCGTVGTSWGFNKCQKCPKKPSYHGYNQMMECLPGYKRVNNTFCQDINECQLQGVC 310
+ C GT C ++ GYN + C+ G+ ++I++C
Sbjct: 301 LMPNACQNGGT------CHN-----THGGYNCV--CVNGW--TGEDCSENIDDCASAACF 345
Query: 311 PNGECLNTMGSYRCTCKIGFGPDPTFSSCVPDPPVISEEKGPCYRLVSSGRQC-MHPLSV 369
C + + S+ C C G T C + IS PC + G C +P++
Sbjct: 346 HGATCHDRVASFYCECPHG----RTGLLCHLNDACIS---NPC----NEGSNCDTNPVN- 393
Query: 370 HLTKQLCCCSVGKAWGPHCEK 390
K +C C G GP C +
Sbjct: 394 --GKAICTCPSGYT-GPACSQ 411
Score = 43.9 bits (102), Expect = 0.001
Identities = 32/119 (26%), Positives = 47/119 (39%), Gaps = 13/119 (10%)
Query: 231 GRCFQETIGSQCGKALPGLSKQEDCCGTVGTSWGFNKCQ---KCPKKPSYHGYNQMMECL 287
G C + G +C LP C V + C+ +C + Y ++ + C
Sbjct: 804 GTCIDDVAGYKCNCLLPYTGAT---CEVVLAPCAPSPCRNGGECRQSEDYESFSCV--CP 858
Query: 288 PGYKRVNNTFCQDINECQLQGVCPNGECLNTMGSYRCTCKIGFGP---DPTFSSCVPDP 343
G++ T DINEC L C NT G YRC C+ G+ + C P+P
Sbjct: 859 TGWQ--GQTCEVDINECVLSPCRHGASCQNTHGGYRCHCQAGYSGRNCETDIDDCRPNP 915
Score = 40.4 bits (93), Expect = 0.012
Identities = 67/257 (26%), Positives = 93/257 (36%), Gaps = 44/257 (17%)
Query: 81 CMNGGQCS---SRDKCQCPPNFTGKLCQIPVHGA-SVPKLYQHSQQPGKALGTHVIHSTH 136
C NGG C + C CPP FTG CQ V+ S P L+ + Q G G++
Sbjct: 992 CFNGGTCVDGINSFTCLCPPGFTGSYCQHDVNECDSQPCLHGGTCQDG--CGSY------ 1043
Query: 137 TLPLTVTSQQGVKVKFPPNIVNIHVKHPPE---ASVQIHQVSRIDGPTGQKTKEAQPGQS 193
T QG N+V+ P + Q H R + P+G
Sbjct: 1044 ----RCTCPQGYTGPNCQNLVHWCDSSPCKNGGKCWQTHTQYRCECPSGWTGLYCD--VP 1097
Query: 194 QVSYQGLPVQKTQTIHSTYSHQQVIPHVYPVAAKTQLGRCFQETIGSQCGKALPGLSKQE 253
VS + ++ + H + A T RC GS C E
Sbjct: 1098 SVSCEVAAQRQGVDVARLCQHGGLCVD----AGNTHHCRCQAGYTGSYC----------E 1143
Query: 254 DCCGTVGTSWGFNKCQKCPKKPSYHGYNQMMECLPGYKRVNNTFCQDINECQLQGVCPN- 312
D S CQ Y G +C+ GY VN + ++I+EC L C N
Sbjct: 1144 DLVDECSPS----PCQNGATCTDYLG-GYSCKCVAGYHGVNCS--EEIDEC-LSHPCQNG 1195
Query: 313 GECLNTMGSYRCTCKIG 329
G CL+ +Y+C+C G
Sbjct: 1196 GTCLDLPNTYKCSCPRG 1212
Score = 39.7 bits (91), Expect = 0.020
Identities = 30/102 (29%), Positives = 40/102 (39%), Gaps = 19/102 (18%)
Query: 42 GSCQNSCEKGNTTTLISENGHAADTLTATNFRVVICHL-PCMNGGQC---SSRDKCQCPP 97
G+CQ+ C T G L V C PC NGG+C ++ +C+CP
Sbjct: 1034 GTCQDGCGSYRCTCPQGYTGPNCQNL------VHWCDSSPCKNGGKCWQTHTQYRCECPS 1087
Query: 98 NFTGKLCQIPV---------HGASVPKLYQHSQQPGKALGTH 130
+TG C +P G V +L QH A TH
Sbjct: 1088 GWTGLYCDVPSVSCEVAAQRQGVDVARLCQHGGLCVDAGNTH 1129
Score = 37.7 bits (86), Expect = 0.078
Identities = 21/51 (41%), Positives = 31/51 (60%), Gaps = 7/51 (13%)
Query: 299 QDINECQLQGVCP---NGECLNTMGSYRCTCKIGF-GP--DPTFSSCVPDP 343
QD++EC L G P G+C+NT+GS+ C C G+ GP + + CV +P
Sbjct: 411 QDVDECSL-GANPCEHAGKCINTLGSFECQCLQGYTGPRCEIDVNECVSNP 460
Score = 36.6 bits (83), Expect = 0.17
Identities = 43/167 (25%), Positives = 64/167 (38%), Gaps = 23/167 (13%)
Query: 247 PGLSKQEDCCGTVGTSWGFNKCQKCPKKPSYHGYNQMMECLPGYKRVNNTFCQ-DINECQ 305
P S+ D C S G N C+ K + G + +CL GY C+ D+NEC
Sbjct: 407 PACSQDVDEC-----SLGANPCEHAGKCINTLGSFEC-QCLQGY---TGPRCEIDVNECV 457
Query: 306 LQGVCPNGECLNTMGSYRCTCKIGFGP---DPTFSSCVPDPPVISEEKGPCYRLVSSGRQ 362
+ CL+ +G ++C C G+ + C P + G C ++ Q
Sbjct: 458 SNPCQNDATCLDQIGEFQCICMPGYEGVHCEVNTDECASSPCL---HNGRCLDKINE-FQ 513
Query: 363 CMHPLSVHLTKQLCCCSVGKAWGPHCE---KCPLPGTAAFKEICPGG 406
C P T LC V + C+ KC L G + +C G
Sbjct: 514 CECPTG--FTGHLCQYDVDECASTPCKNGAKC-LDGPNTYTCVCTEG 557
Score = 36.6 bits (83), Expect = 0.17
Identities = 24/81 (29%), Positives = 35/81 (43%), Gaps = 7/81 (8%)
Query: 266 NKCQKCPKKPSYHGYNQMMECLPGYKRVNNTFCQDINECQLQGVCPNGECLNTMGSYRCT 325
N C + S +GY +C PG+ N + NEC+ G C + Y CT
Sbjct: 723 NPCVHGACRDSLNGYK--CDCDPGWSGTNCDI--NNNECESNPCVNGGTCKDMTSGYVCT 778
Query: 326 CKIGF-GPD--PTFSSCVPDP 343
C+ GF GP+ + C +P
Sbjct: 779 CREGFSGPNCQTNINECASNP 799
Score = 35.8 bits (81), Expect = 0.30
Identities = 25/88 (28%), Positives = 36/88 (40%), Gaps = 17/88 (19%)
Query: 34 ICKVTCTKGSCQ--------NSCEKGNTTTLISENGHAADTL---TATNFRVVICHLP-- 80
+C+ T T +C+ + C+ G T + H L T N I P
Sbjct: 205 VCRATHTGPNCERPYVPCSPSPCQNGGTCRPTGDVTHECACLPGFTGQNCEENIDDCPGN 264
Query: 81 -CMNGGQCS---SRDKCQCPPNFTGKLC 104
C NGG C + C+CPP +TG+ C
Sbjct: 265 NCKNGGACVDGVNTYNCRCPPEWTGQYC 292
Score = 35.8 bits (81), Expect = 0.30
Identities = 14/32 (43%), Positives = 20/32 (62%), Gaps = 3/32 (9%)
Query: 80 PCMNGGQCSSRD---KCQCPPNFTGKLCQIPV 108
PC++ G+C + +C+CP FTG LCQ V
Sbjct: 498 PCLHNGRCLDKINEFQCECPTGFTGHLCQYDV 529
Score = 34.3 bits (77), Expect = 0.86
Identities = 25/98 (25%), Positives = 38/98 (38%), Gaps = 15/98 (15%)
Query: 257 GTVGTSWGFNKCQKCPKKPSYHG-------YNQMMECLPGYKRVNNTFCQ-DINECQLQG 308
G GT+ N +C P +G + C G+ N CQ +INEC
Sbjct: 744 GWSGTNCDINN-NECESNPCVNGGTCKDMTSGYVCTCREGFSGPN---CQTNINECASNP 799
Query: 309 VCPNGECLNTMGSYRCTCKI---GFGPDPTFSSCVPDP 343
G C++ + Y+C C + G + + C P P
Sbjct: 800 CLNQGTCIDDVAGYKCNCLLPYTGATCEVVLAPCAPSP 837
Score = 33.5 bits (75), Expect = 1.5
Identities = 21/71 (29%), Positives = 25/71 (35%), Gaps = 11/71 (15%)
Query: 48 CEKGNTTTLISENGHAADTLTATNFRVVICH--------LPCMNGGQCSSRDK---CQCP 96
C+ G T + S F C L C+NGG C S + C C
Sbjct: 1316 CKNGGTCAVASNTARGFICKCPAGFEGATCENDARTCGSLRCLNGGTCISGPRSPTCLCL 1375
Query: 97 PNFTGKLCQIP 107
FTG CQ P
Sbjct: 1376 GPFTGPECQFP 1386
Score = 33.1 bits (74), Expect = 1.9
Identities = 15/47 (31%), Positives = 22/47 (46%), Gaps = 14/47 (29%)
Query: 80 PCMNGGQCSSRD-----KCQCPPNFTGKLCQIPV---------HGAS 112
PC NGG+C + C CP + G+ C++ + HGAS
Sbjct: 837 PCRNGGECRQSEDYESFSCVCPTGWQGQTCEVDINECVLSPCRHGAS 883
Score = 32.7 bits (73), Expect = 2.5
Identities = 36/130 (27%), Positives = 47/130 (36%), Gaps = 20/130 (15%)
Query: 270 KCPKKPSYHGY-------NQMMECLPGYKRVNNTFCQDINECQLQGVCPNG-ECLNTMGS 321
+C +P HG + C GY N CQ++ C NG +C T
Sbjct: 1024 ECDSQPCLHGGTCQDGCGSYRCTCPQGYTGPN---CQNLVHWCDSSPCKNGGKCWQTHTQ 1080
Query: 322 YRCTCKIGFGPDPTFSSCVPDPPVISEEKGPCYRLVSSGRQCMH-PLSVHL-TKQLCCCS 379
YRC C G ++ D P +S E + V R C H L V C C
Sbjct: 1081 YRCECPSG------WTGLYCDVPSVSCEVAAQRQGVDVARLCQHGGLCVDAGNTHHCRCQ 1134
Query: 380 VGKAWGPHCE 389
G G +CE
Sbjct: 1135 AGYT-GSYCE 1143
Score = 32.0 bits (71), Expect = 4.3
Identities = 26/91 (28%), Positives = 39/91 (42%), Gaps = 23/91 (25%)
Query: 39 CTKGSCQNS-------CEKGNTTTLISENGHAADTLTATNFRVVICHLPCMNGGQC---S 88
C G+C++S C+ G + T N + ++ PC+NGG C +
Sbjct: 725 CVHGACRDSLNGYKCDCDPGWSGTNCDINNNECESN------------PCVNGGTCKDMT 772
Query: 89 SRDKCQCPPNFTGKLCQIPVHG-ASVPKLYQ 118
S C C F+G CQ ++ AS P L Q
Sbjct: 773 SGYVCTCREGFSGPNCQTNINECASNPCLNQ 803
Score = 32.0 bits (71), Expect = 4.3
Identities = 15/38 (39%), Positives = 18/38 (47%), Gaps = 3/38 (7%)
Query: 80 PCMNGGQC---SSRDKCQCPPNFTGKLCQIPVHGASVP 114
PC NGG C + KC CP G C+I V + P
Sbjct: 1191 PCQNGGTCLDLPNTYKCSCPRGTQGVHCEINVDDCNPP 1228
Score = 31.6 bits (70), Expect = 5.6
Identities = 30/105 (28%), Positives = 43/105 (40%), Gaps = 20/105 (19%)
Query: 286 CLPGYKRVNNTFCQ-DINECQLQGVCPNGECLNTMGSYRCTCKIGFGPDPTFSSCVPDPP 344
C GY T C+ DI+EC C G C + + ++ C C+ G+ T C +
Sbjct: 554 CTEGY---TGTHCEVDIDECD-PDPCHYGSCKDGVATFTCLCRPGY----TGHHCETNIN 605
Query: 345 VISEEKGPCYRLVSSGRQCMHPLSVHLTKQLCCCSVGKAWGPHCE 389
S + PC G C + + LC C G GP+CE
Sbjct: 606 ECSSQ--PC----RHGGTCQDRDNAY----LCFCLKGTT-GPNCE 639
Score = 31.6 bits (70), Expect = 5.6
Identities = 29/116 (25%), Positives = 42/116 (36%), Gaps = 27/116 (23%)
Query: 279 GYNQMMECLPGYKRVNNTFCQD-INECQLQGVCPNGE-CLNTMGSYRCTCKIGF---GPD 333
G C GY ++C+D ++EC C NG C + +G Y C C G+
Sbjct: 1126 GNTHHCRCQAGY---TGSYCEDLVDECS-PSPCQNGATCTDYLGGYSCKCVAGYHGVNCS 1181
Query: 334 PTFSSCVPDPPVISEEKGPCYRLVSSGRQCMHPLSVHLTKQLCCCSVGKAWGPHCE 389
C+ P + G C L ++ + C C G G HCE
Sbjct: 1182 EEIDECLSHP---CQNGGTCLDLPNTYK--------------CSCPRG-TQGVHCE 1219
Score = 31.2 bits (69), Expect = 7.3
Identities = 26/87 (29%), Positives = 37/87 (42%), Gaps = 14/87 (16%)
Query: 30 FTPSICKVT---CTKGSCQN--SCEKG--NTTTLISENGHAADTLTATNFRVVICHL-PC 81
+T S+C + C C N +CE G T E H L+ N C+ PC
Sbjct: 670 YTGSMCNINIDECAGNPCHNGGTCEDGINGFTCRCPEGYHDPTCLSEVNE----CNSNPC 725
Query: 82 MNGGQCSSRD--KCQCPPNFTGKLCQI 106
++G S + KC C P ++G C I
Sbjct: 726 VHGACRDSLNGYKCDCDPGWSGTNCDI 752
Score = 30.8 bits (68), Expect = 9.5
Identities = 21/64 (32%), Positives = 29/64 (45%), Gaps = 9/64 (14%)
Query: 285 ECLPGYKRVNNTFCQ-DINECQLQGVCPNG-ECLNTMGSYRCTCKIGFGP---DPTFSSC 339
EC G+ CQ D++EC C NG +CL+ +Y C C G+ + C
Sbjct: 515 ECPTGF---TGHLCQYDVDECA-STPCKNGAKCLDGPNTYTCVCTEGYTGTHCEVDIDEC 570
Query: 340 VPDP 343
PDP
Sbjct: 571 DPDP 574
>gi|120587029 signal peptide, CUB domain, EGF-like 1 [Homo sapiens]
Length = 988
Score = 219 bits (559), Expect = 1e-56
Identities = 148/401 (36%), Positives = 198/401 (49%), Gaps = 42/401 (10%)
Query: 631 IDVDECLR-PDVCG-EGHCVNTVGAFRCEYCDSGYRMTQRGRCEDIDECLNP---STCPD 685
+DVDEC D C + C NT +++C C GY+ + +CEDIDEC N C
Sbjct: 32 VDVDECSEGTDDCHIDAICQNTPKSYKC-LCKPGYKGEGK-QCEDIDECENDYYNGGCVH 89
Query: 686 EQCVNSPGSYQCVPCTEGFR----GWNGQCLDVDECLEPNVCANGDCSNLEGSYMCSCHK 741
E C+N PG+Y+C C +GF G N CLDVDEC + N C N GSY C CH
Sbjct: 90 E-CINIPGNYRCT-CFDGFMLAHDGHN--CLDVDECQDNNGGCQQICVNAMGSYECQCHS 145
Query: 742 GYTRTPDHKHCRDIDECQQGNLCVNGQ------CKNT-EGSFRCTCGQGYQLSAAKDQCE 794
G+ + + C I +G C+N C+ T +G C C G+ L+ + C
Sbjct: 146 GFFLSDNQHTC--IHRSNEGMNCMNKDHGCAHICRETPKGGVACDCRPGFDLAQNQKDCT 203
Query: 795 DIDECQHRHLCAHGQCRNTEGSFQCVCDQGYRASGLGDHCEDINECLEDKSVCQRGDCIN 854
C + + C +T+ C C Q Y G C I C + C R C +
Sbjct: 204 LT--CNYGNGGCQHSCEDTDTGPTCGCHQKYALHSDGRTC--IETCAVNNGGCDR-TCKD 258
Query: 855 TAGSYDCTCPDGFQLD-DNKTCQDINEC-EHPGLCGPQGECLNTEGSFHCVCQQGFSISA 912
TA C+CP GF L D KTC+DINEC + G C C NT GSF C C++G+ +
Sbjct: 259 TATGVRCSCPVGFTLQPDGKTCKDINECLVNNGGC--DHFCRNTVGSFECGCRKGYKLLT 316
Query: 913 DGRTCEDIDECVNNTVCDSHGFCDNTAGSFRCLCYQGFQAPQDGQGCVDVNECELLSGVC 972
D RTC+DIDEC CD C N+ GSF+CLC++G+ C DV+EC + +G C
Sbjct: 317 DERTCQDIDECSFERTCDH--ICINSPGSFQCLCHRGY-ILYGTTHCGDVDECSMSNGSC 373
Query: 973 GEAFCENVEGSFLCVCADE-----NQEYSPMTGQCRSRTST 1008
+ C N +GS+ CVC N + TG+C SR T
Sbjct: 374 DQG-CVNTKGSYECVCPPGRRLHWNGKDCVETGKCLSRAKT 413
Score = 205 bits (522), Expect = 2e-52
Identities = 132/405 (32%), Positives = 182/405 (44%), Gaps = 57/405 (14%)
Query: 548 EINECTVNPDICGAGH-CINLPVRYTCICYEGYRFSEQQRKCVDIDECTQVQHL--CSQG 604
+++EC+ D C C N P Y C+C GY+ +Q C DIDEC + C
Sbjct: 33 DVDECSEGTDDCHIDAICQNTPKSYKCLCKPGYKGEGKQ--CEDIDECENDYYNGGCVH- 89
Query: 605 RCENTEGSFLCICPAGFMASEEGTNCIDVDECLRPDVCGEGHCVNTVGAFRCEYCDSGYR 664
C N G++ C C GFM + +G NC+DVDEC + + CVN +G++ C+ C SG+
Sbjct: 90 ECINIPGNYRCTCFDGFMLAHDGHNCLDVDECQDNNGGCQQICVNAMGSYECQ-CHSGFF 148
Query: 665 MTQRG-----RCEDIDECLNPSTCPDEQCVNSP-GSYQC----------------VPCTE 702
++ R + C+N C +P G C + C
Sbjct: 149 LSDNQHTCIHRSNEGMNCMNKDHGCAHICRETPKGGVACDCRPGFDLAQNQKDCTLTCNY 208
Query: 703 GFRGWNGQCLDVDE------------------CLEPNVCANGDCS----NLEGSYMCSCH 740
G G C D D C+E NG C + CSC
Sbjct: 209 GNGGCQHSCEDTDTGPTCGCHQKYALHSDGRTCIETCAVNNGGCDRTCKDTATGVRCSCP 268
Query: 741 KGYTRTPDHKHCRDIDECQQGNLCVNGQCKNTEGSFRCTCGQGYQLSAAKDQCEDIDECQ 800
G+T PD K C+DI+EC N + C+NT GSF C C +GY+L + C+DIDEC
Sbjct: 269 VGFTLQPDGKTCKDINECLVNNGGCDHFCRNTVGSFECGCRKGYKLLTDERTCQDIDECS 328
Query: 801 HRHLCAHGQCRNTEGSFQCVCDQGYRASGLGDHCEDINECLEDKSVCQRGDCINTAGSYD 860
C H C N+ GSFQC+C +GY G HC D++EC C +G C+NT GSY+
Sbjct: 329 FERTCDH-ICINSPGSFQCLCHRGYILYGT-THCGDVDECSMSNGSCDQG-CVNTKGSYE 385
Query: 861 CTCPDGFQLDDN-KTCQDINECEHPGLCGPQGE--CLNTEGSFHC 902
C CP G +L N K C + +C P+ + C G C
Sbjct: 386 CVCPPGRRLHWNGKDCVETGKCLSRAKTSPRAQLSCSKAGGVESC 430
Score = 128 bits (321), Expect = 4e-29
Identities = 103/379 (27%), Positives = 149/379 (39%), Gaps = 41/379 (10%)
Query: 836 DINECLEDKSVCQ-RGDCINTAGSYDCTCPDGFQLDDNKTCQDINECEHPGLCGP-QGEC 893
D++EC E C C NT SY C C G++ + K C+DI+ECE+ G EC
Sbjct: 33 DVDECSEGTDDCHIDAICQNTPKSYKCLCKPGYK-GEGKQCEDIDECENDYYNGGCVHEC 91
Query: 894 LNTEGSFHCVCQQGFSISADGRTCEDIDECV-NNTVCDSHGFCDNTAGSFRCLCYQGFQA 952
+N G++ C C GF ++ DG C D+DEC NN C C N GS+ C C+ GF
Sbjct: 92 INIPGNYRCTCFDGFMLAHDGHNCLDVDECQDNNGGCQQ--ICVNAMGSYECQCHSGFFL 149
Query: 953 PQDGQGCVDVNE----CELLSGVCGEAFCENVEGSFLCVCAD-----ENQEYSPMT---- 999
+ C+ + C C E +G C C +NQ+ +T
Sbjct: 150 SDNQHTCIHRSNEGMNCMNKDHGCAHICRETPKGGVACDCRPGFDLAQNQKDCTLTCNYG 209
Query: 1000 -GQCRSRTSTDLDVDVDQPKEEKKECYYN---------LNDASLCDNVLAPNVTKQECCC 1049
G C+ + D D +K + + +N+ CD T C C
Sbjct: 210 NGGCQ-HSCEDTDTGPTCGCHQKYALHSDGRTCIETCAVNNGG-CDRTCKDTATGVRCSC 267
Query: 1050 TSGAGW---GDNCEIFPCPVLGTAEFTEMCPKGKGFVPAGESSSE---AGGENYKDADEC 1103
G G C+ ++ C G G +D DEC
Sbjct: 268 PVGFTLQPDGKTCKDINECLVNNGGCDHFCRNTVGSFECGCRKGYKLLTDERTCQDIDEC 327
Query: 1104 LLFGQEICKNGFCLNTRPGYECYCKQGTYYDPVKLQCFDMDECQDPSSCIDGQCVNTEGS 1163
+ C + C+N+ ++C C +G Y C D+DEC + D CVNT+GS
Sbjct: 328 SF--ERTCDH-ICINSPGSFQCLCHRG-YILYGTTHCGDVDECSMSNGSCDQGCVNTKGS 383
Query: 1164 YNCFCTHPMVLDASEKRCI 1182
Y C C L + K C+
Sbjct: 384 YECVCPPGRRLHWNGKDCV 402
Score = 78.2 bits (191), Expect = 5e-14
Identities = 81/315 (25%), Positives = 113/315 (35%), Gaps = 51/315 (16%)
Query: 1086 GESSSEAGGENYKDADECLLFGQEICKNGFCLNTRPGYECYCKQGTYYDPVKLQCFDMDE 1145
G + +G D DEC + + C NT Y+C CK G Y QC D+DE
Sbjct: 20 GRLAGGSGLPGSVDVDECSEGTDDCHIDAICQNTPKSYKCLCKPG--YKGEGKQCEDIDE 77
Query: 1146 CQDP---SSCIDGQCVNTEGSYNCFCTHPMVLDASEKRCIRPAESNEQIEETDVYQDLCW 1202
C++ C+ +C+N G+Y C C +L C+ + +E + Q +C
Sbjct: 78 CENDYYNGGCVH-ECINIPGNYRCTCFDGFMLAHDGHNCL---DVDECQDNNGGCQQICV 133
Query: 1203 EHL-SDEYVCSRPLVGKQTTYTECCCLYGEAWGMQC------------------ALCPLK 1243
+ S E C +T C++ GM C C +
Sbjct: 134 NAMGSYECQCHSGFFLSDNQHT---CIHRSNEGMNCMNKDHGCAHICRETPKGGVACDCR 190
Query: 1244 DSDDYAQ-------LCNIPVTGRRQPYGRDALVDFSEQYTPEADPYFIQDRFLNSFEELQ 1296
D AQ CN YG E Q L+S
Sbjct: 191 PGFDLAQNQKDCTLTCN---------YGNGGCQHSCEDTDTGPTCGCHQKYALHSDGRTC 241
Query: 1297 AEECGILNGCENGRCVRVQEGYTCDCFDGYHLDTAKMTCVDVNECDELNNRMSLCKNAKC 1356
E C + NG + C G C C G+ L TC D+NEC +NN C + C
Sbjct: 242 IETCAVNNGGCDRTCKDTATGVRCSCPVGFTLQPDGKTCKDINEC-LVNN--GGCDHF-C 297
Query: 1357 INTDGSYKCLCLPGY 1371
NT GS++C C GY
Sbjct: 298 RNTVGSFECGCRKGY 312
Score = 76.3 bits (186), Expect = 2e-13
Identities = 80/314 (25%), Positives = 110/314 (35%), Gaps = 64/314 (20%)
Query: 1094 GENYKDADECLLFGQEICKNGFC----LNTRPGYECYCKQGTYYDPVKLQCFDMDECQDP 1149
G+ +D DEC + NG C +N Y C C G C D+DECQD
Sbjct: 69 GKQCEDIDEC----ENDYYNGGCVHECINIPGNYRCTCFDGFMLAHDGHNCLDVDECQDN 124
Query: 1150 SSCIDGQCVNTEGSYNCFCTHPMVLDASEKRCI-RPAESNEQIEETDVYQDLCWEHLSDE 1208
+ CVN GSY C C L ++ CI R E + + +C E
Sbjct: 125 NGGCQQICVNAMGSYECQCHSGFFLSDNQHTCIHRSNEGMNCMNKDHGCAHICRETPKGG 184
Query: 1209 YVCS-RPLVGKQTTYTECC--CLYGEAW-------------------------GMQCALC 1240
C RP +C C YG G C
Sbjct: 185 VACDCRPGFDLAQNQKDCTLTCNYGNGGCQHSCEDTDTGPTCGCHQKYALHSDGRTCIET 244
Query: 1241 PLKDSDDYAQLCNIPVTGRRQ--PYGRDALVDFSEQYTPEADPYFIQDRFLNSFEELQAE 1298
++ + C TG R P G +T + D +D
Sbjct: 245 CAVNNGGCDRTCKDTATGVRCSCPVG----------FTLQPDGKTCKD----------IN 284
Query: 1299 ECGILNGCENGRCVRVQEGYTCDCFDGYHLDTAKMTCVDVNECDELNNRMSLCKNAKCIN 1358
EC + NG + C + C C GY L T + TC D++EC + C + CIN
Sbjct: 285 ECLVNNGGCDHFCRNTVGSFECGCRKGYKLLTDERTCQDIDEC----SFERTCDHI-CIN 339
Query: 1359 TDGSYKCLCLPGYV 1372
+ GS++CLC GY+
Sbjct: 340 SPGSFQCLCHRGYI 353
Score = 60.8 bits (146), Expect = 9e-09
Identities = 30/93 (32%), Positives = 46/93 (49%), Gaps = 12/93 (12%)
Query: 1296 QAEECGILNGCENG--------RCVRVQEGYTCDCFDGYHLDTAKMTCVDVNECDELNNR 1347
+ ++C ++ CEN C+ + Y C CFDG+ L C+DV+EC + N
Sbjct: 68 EGKQCEDIDECENDYYNGGCVHECINIPGNYRCTCFDGFMLAHDGHNCLDVDECQDNNGG 127
Query: 1348 MSLCKNAKCINTDGSYKCLCLPGYVPSDKPNYC 1380
C+ C+N GSY+C C G+ SD + C
Sbjct: 128 ---CQQI-CVNAMGSYECQCHSGFFLSDNQHTC 156
Score = 48.5 bits (114), Expect = 4e-05
Identities = 37/117 (31%), Positives = 51/117 (43%), Gaps = 13/117 (11%)
Query: 243 GKALPGLSKQEDCCGTVGTSWGFNKCQKCPKKPSYHGYNQMMECLPGYKRVNNTFCQDIN 302
G LPG ++C CQ PK Y + C PGYK C+DI+
Sbjct: 25 GSGLPGSVDVDECSEGTDDCHIDAICQNTPKS-----YKCL--CKPGYKGEGKQ-CEDID 76
Query: 303 ECQ---LQGVCPNGECLNTMGSYRCTCKIGFGPDPTFSSCVPDPPVISEEKGPCYRL 356
EC+ G C + EC+N G+YRCTC GF +C+ D + G C ++
Sbjct: 77 ECENDYYNGGCVH-ECINIPGNYRCTCFDGFMLAHDGHNCL-DVDECQDNNGGCQQI 131
Score = 43.1 bits (100), Expect = 0.002
Identities = 24/66 (36%), Positives = 29/66 (43%), Gaps = 2/66 (3%)
Query: 286 CLPGYKRVNNTFCQDINECQLQ-GVCPNGECLNTMGSYRCTCKIGFGPDPTFSSCVPDPP 344
C GY T C D++EC + G C G C+NT GSY C C G CV
Sbjct: 348 CHRGYILYGTTHCGDVDECSMSNGSCDQG-CVNTKGSYECVCPPGRRLHWNGKDCVETGK 406
Query: 345 VISEEK 350
+S K
Sbjct: 407 CLSRAK 412
Score = 40.8 bits (94), Expect = 0.009
Identities = 18/46 (39%), Positives = 28/46 (60%), Gaps = 2/46 (4%)
Query: 286 CLPGYKRVNNT-FCQDINECQLQGVCPNGECLNTMGSYRCTCKIGF 330
C GYK + + CQDI+EC + C + C+N+ GS++C C G+
Sbjct: 308 CRKGYKLLTDERTCQDIDECSFERTCDH-ICINSPGSFQCLCHRGY 352
Score = 40.0 bits (92), Expect = 0.016
Identities = 25/88 (28%), Positives = 33/88 (37%), Gaps = 1/88 (1%)
Query: 1295 LQAEECGILNGCENGRCVRVQEGYTCDCFDGYHLDTAKMTCVD-VNECDELNNRMSLCKN 1353
L +EC NG CV Y C C G+ L + TC+ NE N+ C +
Sbjct: 116 LDVDECQDNNGGCQQICVNAMGSYECQCHSGFFLSDNQHTCIHRSNEGMNCMNKDHGCAH 175
Query: 1354 AKCINTDGSYKCLCLPGYVPSDKPNYCT 1381
G C C PG+ + CT
Sbjct: 176 ICRETPKGGVACDCRPGFDLAQNQKDCT 203
Score = 39.3 bits (90), Expect = 0.027
Identities = 20/70 (28%), Positives = 35/70 (50%), Gaps = 4/70 (5%)
Query: 1311 CVRVQEGYTCDCFDGYHLDTAKMTCVDVNECDELNNRMSLCKNAKCINTDGSYKCLCLPG 1370
C + Y C C GY + + C D++EC+ N+ + +CIN G+Y+C C G
Sbjct: 50 CQNTPKSYKCLCKPGYKGEGKQ--CEDIDECE--NDYYNGGCVHECINIPGNYRCTCFDG 105
Query: 1371 YVPSDKPNYC 1380
++ + + C
Sbjct: 106 FMLAHDGHNC 115
Score = 36.2 bits (82), Expect = 0.23
Identities = 14/33 (42%), Positives = 21/33 (63%)
Query: 298 CQDINECQLQGVCPNGECLNTMGSYRCTCKIGF 330
C+DINEC + + C NT+GS+ C C+ G+
Sbjct: 280 CKDINECLVNNGGCDHFCRNTVGSFECGCRKGY 312
>gi|31377568 signal peptide, CUB domain, EGF-like 3 [Homo sapiens]
Length = 993
Score = 204 bits (519), Expect = 5e-52
Identities = 121/364 (33%), Positives = 171/364 (46%), Gaps = 51/364 (14%)
Query: 548 EINECTVNPDICGAGH-CINLPVRYTCICYEGYRFSEQQRKCVDIDECTQVQHLCSQGRC 606
+++EC D C C N P Y CIC GY + + C D+DEC + + C
Sbjct: 29 DVDECVEGTDNCHIDAICQNTPRSYKCICKSGY--TGDGKHCKDVDECEREDNAGCVHDC 86
Query: 607 ENTEGSFLCICPAGFMASEEGTNCIDVDECLRPDVCGEGHCVNTVGAFRCEYCDSGYRMT 666
N G++ C C GF + +G NC+DVDEC + + CVN +G++ C +C G+ ++
Sbjct: 87 VNIPGNYRCTCYDGFHLAHDGHNCLDVDECAEGNGGCQQSCVNMMGSYEC-HCREGFFLS 145
Query: 667 QRG-----RCEDIDECLNPSTCPDEQCVNSP-GSYQC----------------VPCTEGF 704
R E+ C+N + C +P G C + C G
Sbjct: 146 DNQHTCIQRPEEGMNCMNKNHGCAHICRETPKGGIACECRPGFELTKNQRDCKLTCNYGN 205
Query: 705 RGWNGQCLDVDE------------------CLEPNVCANGDCSN----LEGSYMCSCHKG 742
G C D ++ C+E NG C + C+C G
Sbjct: 206 GGCQHTCDDTEQGPRCGCHIKFVLHTDGKTCIETCAVNNGGCDSKCHDAATGVHCTCPVG 265
Query: 743 YTRTPDHKHCRDIDECQQGNLCVNGQCKNTEGSFRCTCGQGYQLSAAKDQCEDIDECQHR 802
+ PD K C+DIDEC+ N + C+NT GSF C+C +GY+L + C+DIDEC
Sbjct: 266 FMLQPDRKTCKDIDECRLNNGGCDHICRNTVGSFECSCKKGYKLLINERNCQDIDECSFD 325
Query: 803 HLCAHGQCRNTEGSFQCVCDQGYRASGLGDHCEDINECLEDKSVCQRGDCINTAGSYDCT 862
C H C NT GSFQC+C +GY G+ HC D++EC ++ C+ G CINT GSY CT
Sbjct: 326 RTCDH-ICVNTPGSFQCLCHRGYLLYGI-THCGDVDECSINRGGCRFG-CINTPGSYQCT 382
Query: 863 CPDG 866
CP G
Sbjct: 383 CPAG 386
Score = 202 bits (515), Expect = 1e-51
Identities = 129/364 (35%), Positives = 177/364 (48%), Gaps = 55/364 (15%)
Query: 672 EDIDECLNPS-TCP-DEQCVNSPGSYQCVPCTEGFRGWNGQCLDVDEC-LEPNVCANGDC 728
+D+DEC+ + C D C N+P SY+C+ C G+ G C DVDEC E N DC
Sbjct: 28 QDVDECVEGTDNCHIDAICQNTPRSYKCI-CKSGYTGDGKHCKDVDECEREDNAGCVHDC 86
Query: 729 SNLEGSYMCSCHKGYTRTPDHKHCRDIDECQQGNLCVNGQCKNTEGSFRCTCGQGYQLSA 788
N+ G+Y C+C+ G+ D +C D+DEC +GN C N GS+ C C +G+ LS
Sbjct: 87 VNIPGNYRCTCYDGFHLAHDGHNCLDVDECAEGNGGCQQSCVNMMGSYECHCREGFFLSD 146
Query: 789 AKDQC----EDIDECQHR-HLCAHGQCRNT-EGSFQCVCDQGYRAS-------------- 828
+ C E+ C ++ H CAH CR T +G C C G+ +
Sbjct: 147 NQHTCIQRPEEGMNCMNKNHGCAH-ICRETPKGGIACECRPGFELTKNQRDCKLTCNYGN 205
Query: 829 -GLGDHCEDINE------------------CLEDKSVCQRG---DCINTAGSYDCTCPDG 866
G C+D + C+E +V G C + A CTCP G
Sbjct: 206 GGCQHTCDDTEQGPRCGCHIKFVLHTDGKTCIETCAVNNGGCDSKCHDAATGVHCTCPVG 265
Query: 867 FQLD-DNKTCQDINECE-HPGLCGPQGECLNTEGSFHCVCQQGFSISADGRTCEDIDECV 924
F L D KTC+DI+EC + G C C NT GSF C C++G+ + + R C+DIDEC
Sbjct: 266 FMLQPDRKTCKDIDECRLNNGGC--DHICRNTVGSFECSCKKGYKLLINERNCQDIDECS 323
Query: 925 NNTVCDSHGFCDNTAGSFRCLCYQGFQAPQDGQGCVDVNECELLSGVCGEAFCENVEGSF 984
+ CD C NT GSF+CLC++G+ C DV+EC + G C C N GS+
Sbjct: 324 FDRTCDH--ICVNTPGSFQCLCHRGYLL-YGITHCGDVDECSINRGGC-RFGCINTPGSY 379
Query: 985 LCVC 988
C C
Sbjct: 380 QCTC 383
Score = 196 bits (498), Expect = 1e-49
Identities = 130/399 (32%), Positives = 188/399 (47%), Gaps = 25/399 (6%)
Query: 580 RFSEQQRKCVDIDECTQVQHLCS-QGRCENTEGSFLCICPAGFMASEEGTNCIDVDECLR 638
R ++ + D+DEC + C C+NT S+ CIC +G+ +G +C DVDEC R
Sbjct: 19 RAAQYSKAAQDVDECVEGTDNCHIDAICQNTPRSYKCICKSGYTG--DGKHCKDVDECER 76
Query: 639 PDVCGEGH-CVNTVGAFRCEYCDSGYRMTQRGR-CEDIDECLNPSTCPDEQCVNSPGSYQ 696
D G H CVN G +RC C G+ + G C D+DEC + + CVN GSY+
Sbjct: 77 EDNAGCVHDCVNIPGNYRCT-CYDGFHLAHDGHNCLDVDECAEGNGGCQQSCVNMMGSYE 135
Query: 697 CVPCTEGFRGWNGQ--CLDVDE----CLEPNV-CANGDCSNLEGSYMCSCHKGYTRTPDH 749
C C EGF + Q C+ E C+ N CA+ +G C C G+ T +
Sbjct: 136 C-HCREGFFLSDNQHTCIQRPEEGMNCMNKNHGCAHICRETPKGGIACECRPGFELTKNQ 194
Query: 750 KHCRDIDECQQGNLCVNGQCKNTEGSFRCTCGQGYQLSAAKDQCEDIDECQHRHLCAHGQ 809
+ C+ C GN C +TE RC C + L C I+ C + +
Sbjct: 195 RDCKLT--CNYGNGGCQHTCDDTEQGPRCGCHIKFVLHTDGKTC--IETCAVNNGGCDSK 250
Query: 810 CRNTEGSFQCVCDQGYRASGLGDHCEDINECLEDKSVCQRGDCINTAGSYDCTCPDGFQL 869
C + C C G+ C+DI+EC + C C NT GS++C+C G++L
Sbjct: 251 CHDAATGVHCTCPVGFMLQPDRKTCKDIDECRLNNGGCDH-ICRNTVGSFECSCKKGYKL 309
Query: 870 DDN-KTCQDINECEHPGLCGPQGECLNTEGSFHCVCQQGFSISADGRTCEDIDECVNNTV 928
N + CQDI+EC C C+NT GSF C+C +G+ + C D+DEC N
Sbjct: 310 LINERNCQDIDECSFDRTC--DHICVNTPGSFQCLCHRGYLLYGITH-CGDVDECSINRG 366
Query: 929 CDSHGFCDNTAGSFRCLCYQG-FQAPQDGQGCVDVNECE 966
G C NT GS++C C G + +G+ C + +C+
Sbjct: 367 GCRFG-CINTPGSYQCTCPAGQGRLHWNGKDCTEPLKCQ 404
Score = 151 bits (382), Expect = 4e-36
Identities = 125/430 (29%), Positives = 178/430 (41%), Gaps = 117/430 (27%)
Query: 750 KHCRDIDECQQG--NLCVNGQCKNTEGSFRCTCGQGYQLSAAKDQCEDIDECQHRHL--C 805
K +D+DEC +G N ++ C+NT S++C C GY + C+D+DEC+ C
Sbjct: 25 KAAQDVDECVEGTDNCHIDAICQNTPRSYKCICKSGY--TGDGKHCKDVDECEREDNAGC 82
Query: 806 AHGQCRNTEGSFQCVCDQGYRASGLGDHCEDINECLEDKSVCQRGDCINTAGSYDCTCPD 865
H C N G+++C C G+ + G +C D++EC E CQ+ C+N GSY+C C +
Sbjct: 83 VH-DCVNIPGNYRCTCYDGFHLAHDGHNCLDVDECAEGNGGCQQS-CVNMMGSYECHCRE 140
Query: 866 GFQLDDNK-----------TCQDINE-CEH---------------PGL------------ 886
GF L DN+ C + N C H PG
Sbjct: 141 GFFLSDNQHTCIQRPEEGMNCMNKNHGCAHICRETPKGGIACECRPGFELTKNQRDCKLT 200
Query: 887 C-----GPQGECLNTEGSFHCVCQQGFSISADGRTCEDIDEC-VNNTVCDSHGFCDNTAG 940
C G Q C +TE C C F + DG+TC I+ C VNN CDS C + A
Sbjct: 201 CNYGNGGCQHTCDDTEQGPRCGCHIKFVLHTDGKTC--IETCAVNNGGCDSK--CHDAAT 256
Query: 941 SFRCLCYQGFQAPQDGQGCVDVNECELLSGVCGEAFCENVEGSFLCVCADENQEYSPMTG 1000
C C GF D + C D++EC L +G C + C N GSF C C + Y +
Sbjct: 257 GVHCTCPVGFMLQPDRKTCKDIDECRLNNGGC-DHICRNTVGSFECSC---KKGYKLLIN 312
Query: 1001 QCRSRTSTDLDVDVDQPKEEKKECYYNLNDASLCDNVLAPNVTKQECCCTSGAGWGDNCE 1060
+ R D+D EC ++ CD++ C T G+
Sbjct: 313 E---RNCQDID-----------ECSFDRT----CDHI---------CVNTPGS------- 338
Query: 1061 IFPCPVLGTAEFTEMCPKGKGFVPAGESSSEAGGENYKDADECLLFGQEICKNGFCLNTR 1120
F C +C +G G + D DEC + + C+ G C+NT
Sbjct: 339 -FQC----------LCHRGYLLY---------GITHCGDVDECSI-NRGGCRFG-CINTP 376
Query: 1121 PGYECYCKQG 1130
Y+C C G
Sbjct: 377 GSYQCTCPAG 386
Score = 137 bits (345), Expect = 7e-32
Identities = 109/369 (29%), Positives = 147/369 (39%), Gaps = 70/369 (18%)
Query: 826 RASGLGDHCEDINECLEDKSVCQ-RGDCINTAGSYDCTCPDGFQLDDNKTCQDINECEHP 884
RA+ +D++EC+E C C NT SY C C G+ D K C+D++ECE
Sbjct: 19 RAAQYSKAAQDVDECVEGTDNCHIDAICQNTPRSYKCICKSGYT-GDGKHCKDVDECERE 77
Query: 885 GLCGPQGECLNTEGSFHCVCQQGFSISADGRTCEDIDECV-NNTVCDSHGFCDNTAGSFR 943
G +C+N G++ C C GF ++ DG C D+DEC N C C N GS+
Sbjct: 78 DNAGCVHDCVNIPGNYRCTCYDGFHLAHDGHNCLDVDECAEGNGGCQQS--CVNMMGSYE 135
Query: 944 CLCYQGF----------QAPQDGQGCVDVNECELLSGVCGEAFCENVEGSFLCVC----- 988
C C +GF Q P++G C++ N C E +G C C
Sbjct: 136 CHCREGFFLSDNQHTCIQRPEEGMNCMNKNH------GCAHICRETPKGGIACECRPGFE 189
Query: 989 ADENQEYSPMT-----GQCRSRTSTDLDVDVDQPKEEKKECYYNLNDASLCDNVLAPNVT 1043
+NQ +T G C+ T D E+ C ++ D T
Sbjct: 190 LTKNQRDCKLTCNYGNGGCQ-HTCDD--------TEQGPRCGCHIKFVLHTD-----GKT 235
Query: 1044 KQECCCTSGAGWGDNCEIFPCPVLGTAEFTEMCPKGKGFVPAGESSSEAGGENYKDADEC 1103
E C + G C V T CP G P ++ KD DEC
Sbjct: 236 CIETCAVNNGGCDSKCHDAATGVHCT------CPVGFMLQPDRKTC--------KDIDEC 281
Query: 1104 LLFGQEICKNG----FCLNTRPGYECYCKQGTYYDPVKLQCFDMDECQDPSSCIDGQCVN 1159
L NG C NT +EC CK+G + C D+DEC +C D CVN
Sbjct: 282 RL------NNGGCDHICRNTVGSFECSCKKGYKLLINERNCQDIDECSFDRTC-DHICVN 334
Query: 1160 TEGSYNCFC 1168
T GS+ C C
Sbjct: 335 TPGSFQCLC 343
Score = 115 bits (287), Expect = 4e-25
Identities = 90/327 (27%), Positives = 134/327 (40%), Gaps = 51/327 (15%)
Query: 872 NKTCQDINEC-EHPGLCGPQGECLNTEGSFHCVCQQGFSISADGRTCEDIDECVNNTVCD 930
+K QD++EC E C C NT S+ C+C+ G++ DG+ C+D+DEC
Sbjct: 24 SKAAQDVDECVEGTDNCHIDAICQNTPRSYKCICKSGYT--GDGKHCKDVDECEREDNAG 81
Query: 931 SHGFCDNTAGSFRCLCYQGFQAPQDGQGCVDVNECELLSGVCGEAFCENVEGSFLCVCAD 990
C N G++RC CY GF DG C+DV+EC +G C ++ C N+ GS+ C C +
Sbjct: 82 CVHDCVNIPGNYRCTCYDGFHLAHDGHNCLDVDECAEGNGGCQQS-CVNMMGSYECHCRE 140
Query: 991 -----ENQE---YSPMTGQ-CRSRTSTDLDVDVDQPKEEKKECYYNLNDASLCDNVLAPN 1041
+NQ P G C ++ + + PK C+
Sbjct: 141 GFFLSDNQHTCIQRPEEGMNCMNKNHGCAHICRETPK-----------GGIACECRPGFE 189
Query: 1042 VTKQECCCTSGAGWGDN-CEIFPCPVLGTAEFTEMCPKGKGFVPAGESSSEAGGENYKDA 1100
+TK + C +G+ C+ T + TE P+ + D
Sbjct: 190 LTKNQRDCKLTCNYGNGGCQ-------HTCDDTEQGPR---------CGCHIKFVLHTDG 233
Query: 1101 DECLLFGQEIC--KNGFC----LNTRPGYECYCKQGTYYDPVKLQCFDMDECQDPSSCID 1154
C+ E C NG C + G C C G P + C D+DEC+ + D
Sbjct: 234 KTCI----ETCAVNNGGCDSKCHDAATGVHCTCPVGFMLQPDRKTCKDIDECRLNNGGCD 289
Query: 1155 GQCVNTEGSYNCFCTHPMVLDASEKRC 1181
C NT GS+ C C L +E+ C
Sbjct: 290 HICRNTVGSFECSCKKGYKLLINERNC 316
Score = 85.5 bits (210), Expect = 3e-16
Identities = 75/289 (25%), Positives = 104/289 (35%), Gaps = 43/289 (14%)
Query: 1087 ESSSEAGGENYKDADECLLFGQEICKNGFCLNTRPGYECYCKQGTYYDPVKLQCFDMDEC 1146
+S G++ KD DEC C + C+N Y C C G + C D+DEC
Sbjct: 58 KSGYTGDGKHCKDVDECEREDNAGCVHD-CVNIPGNYRCTCYDGFHLAHDGHNCLDVDEC 116
Query: 1147 QDPSSCIDGQCVNTEGSYNCFCTHPMVLDASEKRCI-RPAESNEQIEETDVYQDLCWEHL 1205
+ + CVN GSY C C L ++ CI RP E + + +C E
Sbjct: 117 AEGNGGCQQSCVNMMGSYECHCREGFFLSDNQHTCIQRPEEGMNCMNKNHGCAHICRETP 176
Query: 1206 SDEYVCS-RPLVGKQTTYTEC--CCLYGEAWGMQCALCPLKDSDDYAQLCNIPVTGRRQP 1262
C RP +C C YG G Q D + C +
Sbjct: 177 KGGIACECRPGFELTKNQRDCKLTCNYGNG-GCQHTC----DDTEQGPRCGCHIKFVLHT 231
Query: 1263 YGRDALVDFSEQYTPEADPYFIQDRFLNSFEELQAEECGILNGCENGRCVRVQEGYTCDC 1322
G+ + E C + NG + +C G C C
Sbjct: 232 DGKTCI-----------------------------ETCAVNNGGCDSKCHDAATGVHCTC 262
Query: 1323 FDGYHLDTAKMTCVDVNECDELNNRMSLCKNAKCINTDGSYKCLCLPGY 1371
G+ L + TC D++EC LNN C + C NT GS++C C GY
Sbjct: 263 PVGFMLQPDRKTCKDIDEC-RLNN--GGCDHI-CRNTVGSFECSCKKGY 307
Score = 80.5 bits (197), Expect = 1e-14
Identities = 114/458 (24%), Positives = 155/458 (33%), Gaps = 98/458 (21%)
Query: 915 RTCEDIDECVNNTV-CDSHGFCDNTAGSFRCLCYQGFQAPQDGQGCVDVNECELLSGVCG 973
+ +D+DECV T C C NT S++C+C G+ DG+ C DV+ECE
Sbjct: 25 KAAQDVDECVEGTDNCHIDAICQNTPRSYKCICKSGYTG--DGKHCKDVDECEREDNAGC 82
Query: 974 EAFCENVEGSFLCVCADENQEYSPMTGQCRSRTSTDLDVDVDQPKEEKKECYYNLNDASL 1033
C N+ G++ C C D + C +DVD+ E C +
Sbjct: 83 VHDCVNIPGNYRCTCYD-GFHLAHDGHNC---------LDVDECAEGNGGCQQS------ 126
Query: 1034 CDNVLAPNVTKQECCCTSGAGWGDNCEIFPCPVLGTAEFTEMCPKGKGFVPAGESSSEAG 1093
C N++ EC C G DN C + E
Sbjct: 127 CVNMMG----SYECHCREGFFLSDN--------------QHTC------IQRPEEGMNCM 162
Query: 1094 GENYKDADECLLFGQEICKNGFCLNTRPGYECYCKQGTYYDPVKLQC-FDMDECQDPSSC 1152
+N+ A C +E K G RPG+E Q KL C + CQ
Sbjct: 163 NKNHGCAHIC----RETPKGGIACECRPGFELTKNQRD----CKLTCNYGNGGCQHT--- 211
Query: 1153 IDGQCVNTEGSYNCFCTHPMVLDASEKRCIRPAESNEQIEETDVYQDLCWEHLSDEYVCS 1212
C +TE C C VL K CI N ++ +
Sbjct: 212 ----CDDTEQGPRCGCHIKFVLHTDGKTCIETCAVNNGGCDSKCHD-------------- 253
Query: 1213 RPLVGKQTTYTECCCLYGEAWGMQCALCPLKDSDDYAQLCNIPVTGRRQPYGRDALVDFS 1272
T C C G C KD D+ C + G R+ + F
Sbjct: 254 ------AATGVHCTCPVGFMLQPDRKTC--KDIDE----CRLN-NGGCDHICRNTVGSF- 299
Query: 1273 EQYTPEADPYFIQDRFLNSFEELQAEECGILNGCENGRCVRVQEGYTCDCFDGYHLDTAK 1332
E + I +R +EC C++ CV + C C GY L
Sbjct: 300 ECSCKKGYKLLINERNCQDI-----DECSFDRTCDH-ICVNTPGSFQCLCHRGYLL-YGI 352
Query: 1333 MTCVDVNECDELNNRMSLCKNAKCINTDGSYKCLCLPG 1370
C DV+EC NR C+ CINT GSY+C C G
Sbjct: 353 THCGDVDECS--INRGG-CRFG-CINTPGSYQCTCPAG 386
Score = 60.8 bits (146), Expect = 9e-09
Identities = 30/76 (39%), Positives = 42/76 (55%), Gaps = 5/76 (6%)
Query: 1305 GCENGRCVRVQEGYTCDCFDGYHLDTAKMTCVDVNECDELNNRMSLCKNAKCINTDGSYK 1364
GC + CV + Y C C+DG+HL C+DV+EC E N C+ + C+N GSY+
Sbjct: 81 GCVHD-CVNIPGNYRCTCYDGFHLAHDGHNCLDVDECAEGNGG---CQQS-CVNMMGSYE 135
Query: 1365 CLCLPGYVPSDKPNYC 1380
C C G+ SD + C
Sbjct: 136 CHCREGFFLSDNQHTC 151
Score = 44.7 bits (104), Expect = 6e-04
Identities = 22/47 (46%), Positives = 28/47 (59%), Gaps = 2/47 (4%)
Query: 286 CLPGYKRVNNTFCQDINECQL-QGVCPNGECLNTMGSYRCTCKIGFG 331
C GY T C D++EC + +G C G C+NT GSY+CTC G G
Sbjct: 343 CHRGYLLYGITHCGDVDECSINRGGCRFG-CINTPGSYQCTCPAGQG 388
Score = 43.5 bits (101), Expect = 0.001
Identities = 20/46 (43%), Positives = 27/46 (58%), Gaps = 2/46 (4%)
Query: 286 CLPGYKR-VNNTFCQDINECQLQGVCPNGECLNTMGSYRCTCKIGF 330
C GYK +N CQDI+EC C + C+NT GS++C C G+
Sbjct: 303 CKKGYKLLINERNCQDIDECSFDRTCDH-ICVNTPGSFQCLCHRGY 347
Score = 38.9 bits (89), Expect = 0.035
Identities = 15/33 (45%), Positives = 23/33 (69%)
Query: 298 CQDINECQLQGVCPNGECLNTMGSYRCTCKIGF 330
C+DI+EC+L + C NT+GS+ C+CK G+
Sbjct: 275 CKDIDECRLNNGGCDHICRNTVGSFECSCKKGY 307
Score = 38.5 bits (88), Expect = 0.046
Identities = 21/65 (32%), Positives = 31/65 (47%), Gaps = 3/65 (4%)
Query: 281 NQMMECLPGYKRVNNTF-CQDINEC-QLQGVCPNGECLNTMGSYRCTCKIGFGPDPTFSS 338
N C G+ ++ C D++EC + G C C+N MGSY C C+ GF +
Sbjct: 92 NYRCTCYDGFHLAHDGHNCLDVDECAEGNGGCQQS-CVNMMGSYECHCREGFFLSDNQHT 150
Query: 339 CVPDP 343
C+ P
Sbjct: 151 CIQRP 155
Score = 37.4 bits (85), Expect = 0.10
Identities = 23/70 (32%), Positives = 36/70 (51%), Gaps = 5/70 (7%)
Query: 286 CLPGYKRVNNTFCQDINECQLQ--GVCPNGECLNTMGSYRCTCKIGFGPDPTFSSCVPDP 343
C GY + C+D++EC+ + C + +C+N G+YRCTC GF +C+ D
Sbjct: 57 CKSGYTG-DGKHCKDVDECEREDNAGCVH-DCVNIPGNYRCTCYDGFHLAHDGHNCL-DV 113
Query: 344 PVISEEKGPC 353
+E G C
Sbjct: 114 DECAEGNGGC 123
Score = 33.5 bits (75), Expect = 1.5
Identities = 17/40 (42%), Positives = 22/40 (55%), Gaps = 2/40 (5%)
Query: 1337 DVNECDELNNRMSLCKNAKCINTDGSYKCLCLPGYVPSDK 1376
DV+EC E + + +A C NT SYKC+C GY K
Sbjct: 29 DVDECVEGTDNCHI--DAICQNTPRSYKCICKSGYTGDGK 66
>gi|55770876 notch4 preproprotein [Homo sapiens]
Length = 2003
Score = 203 bits (517), Expect = 8e-52
Identities = 257/959 (26%), Positives = 345/959 (35%), Gaps = 219/959 (22%)
Query: 552 CTVNPDICGAGHCINLPVRYTCICYEGYRFSEQQRKCVDIDECTQVQHLCSQGR-CENTE 610
C+ NP + G G C+ + C C G+ +R D++EC Q C +G C NT
Sbjct: 160 CSANPCVNG-GVCLATYPQIQCHCPPGFEGHACER---DVNECFQDPGPCPKGTSCHNTL 215
Query: 611 GSFLCICPAGFMASEEGTNC-IDVDECLRPDVCGEGHCVNTV----GAFRCEYCDSGYRM 665
GSF C+CP G +EG C + C P C G + F C G+
Sbjct: 216 GSFQCLCPVG----QEGPRCELRAGPC-PPRGCSNGGTCQLMPEKDSTFHLCLCPPGFIG 270
Query: 666 TQRGRCEDIDECLNPSTCPDEQCVNSP------GSYQCVPCTEGFRGWNGQCLDVDECLE 719
CE +NP C QC N +Y C+ C E + GW+ DVDEC
Sbjct: 271 PD---CE-----VNPDNCVSHQCQNGGTCQDGLDTYTCL-CPETWTGWDCS-EDVDECET 320
Query: 720 --PNVCANGD-CSNLEGSYMCSCHKGYTRTPDHKHCRDIDECQQGNLCVNGQCKNTEGSF 776
P C NG C N GS+ C C G+ T ++ +D+C C + GSF
Sbjct: 321 QGPPHCRNGGTCQNSAGSFHCVCVSGWGGTSCEEN---LDDCIAATCAPGSTCIDRVGSF 377
Query: 777 RCTCGQGYQ--LSAAKDQC----------------------------------EDIDEC- 799
C C G L +D C +D+DEC
Sbjct: 378 SCLCPPGRTGLLCHLEDMCLSQPCHGDAQCSTNPLTGSTLCLCQPGYSGPTCHQDLDECL 437
Query: 800 ---QHRHLCAHG-QCRNTEGSFQCVCDQGYRASGLGDHCE-DINECLEDKSVCQRGD-CI 853
Q C HG C NT GSF C+C GY G CE D NECL C G C+
Sbjct: 438 MAQQGPSPCEHGGSCLNTPGSFNCLCPPGYT----GSRCEADHNECLSQP--CHPGSTCL 491
Query: 854 NTAGSYDCTCPDGFQLDDNKTCQ-DINECEHPGLCGPQGECLNTEGSFHCVCQQGFSISA 912
+ ++ C CP G + + C+ + NEC C +C + F C+C GFS
Sbjct: 492 DLLATFHCLCPPGLE---GQLCEVETNECASAP-CLNHADCHDLLNGFQCICLPGFS--- 544
Query: 913 DGRTCE-DIDECVNNTVCDSHGFCDNTAGSFRCLCYQGFQAPQDGQGC-VDVNECELLSG 970
G CE DIDEC ++ C + G C + G+F C C GF+ P+ C +V+EC LS
Sbjct: 545 -GTRCEEDIDEC-RSSPCANGGQCQDQPGAFHCKCLPGFEGPR----CQTEVDEC--LSD 596
Query: 971 VCGE-AFCENVEGSFLCVCADENQEYSPMTGQ------CRSRTSTDLDVDVDQPKEEKKE 1023
C A C ++ G+F C+C S TGQ C + DQ ++K
Sbjct: 597 PCPVGASCLDLPGAFFCLCP------SGFTGQLCEVPLCAPNLCQPKQICKDQ--KDKAN 648
Query: 1024 CYYNLNDASLC---DNVLAPNVTKQECCCTSGAGW-GDNCEI-------FPCPVLGTAEF 1072
C DN + Q C GW G CE PC GT
Sbjct: 649 CLCPDGSPGCAPPEDNCTCHHGHCQRSSCVCDVGWTGPECEAELGGCISAPCAHGGTCY- 707
Query: 1073 TEMCPKGKGFVPAGESSSEAGGENYKDADECLLFGQEICKNGFCLNTRPG-YECYCKQGT 1131
P+ G+ + G ++E C NG N PG Y C C +
Sbjct: 708 ----PQPSGY----NCTCPTGYTGPTCSEEMTACHSGPCLNGGSCNPSPGGYYCTCPP-S 758
Query: 1132 YYDPVKLQC-FDMDECQDPSSCIDGQCVNTEGSYNCFCTHPMVLDASEKRC---IRPAES 1187
+ P QC D C G CVN G+++C C + RC +RP+ +
Sbjct: 759 HTGP---QCQTSTDYCVSAPCFNGGTCVNRPGTFSCLCA----MGFQGPRCEGKLRPSCA 811
Query: 1188 NEQIEETDVYQD-------LC-----------WEHLSDEYVCSRPLVGKQTTYT-ECCCL 1228
+ QD LC L + C R QT + C CL
Sbjct: 812 DSPCRNRATCQDSPQGPRCLCPTGYTGGSCQTLMDLCAQKPCPRNSHCLQTGPSFHCLCL 871
Query: 1229 YGEAWGMQCALCPLKDSDDYAQLCNIPVTGRRQPYGRDALVDFSEQYTPEADPYFIQDRF 1288
G W PL A I V+ G VD Y P F
Sbjct: 872 QG--WTGPLCNLPLSSCQKAALSQGIDVSSLCHNGG--LCVDSGPSYFCHCPPGFQGSLC 927
Query: 1289 LNSFEELQAEECGILNGCENGR-CVRVQEGYTCDCFDGY-------HLDTAKM------- 1333
+ ++ C +NG C+ GY C C GY LD +
Sbjct: 928 QDHVNPCESRPC------QNGATCMAQPSGYLCQCAPGYDGQNCSKELDACQSQPCHNHG 981
Query: 1334 TCV---------------------DVNECDELNNRMSLCKNAKCINTDGSYKCLCLPGY 1371
TC DV+EC L+ A C + ++ C CLPG+
Sbjct: 982 TCTPKPGGFHCACPPGFVGLRCEGDVDEC--LDQPCHPTGTAACHSLANAFYCQCLPGH 1038
Score = 187 bits (476), Expect = 5e-47
Identities = 228/860 (26%), Positives = 308/860 (35%), Gaps = 170/860 (19%)
Query: 551 ECTVNPDICGAGHCINLPV------RYTCICYE---GYRFSEQQRKCVDIDEC-TQ-VQH 599
+C VNPD C + C N YTC+C E G+ SE D+DEC TQ H
Sbjct: 272 DCEVNPDNCVSHQCQNGGTCQDGLDTYTCLCPETWTGWDCSE------DVDECETQGPPH 325
Query: 600 LCSQGRCENTEGSFLCICPAGFMASEEGTNCID-VDECLRPDVCGEGHCVNTVGAFRCEY 658
+ G C+N+ GSF C+C +G+ GT+C + +D+C+ C++ VG+F C
Sbjct: 326 CRNGGTCQNSAGSFHCVCVSGW----GGTSCEENLDDCIAATCAPGSTCIDRVGSFSC-L 380
Query: 659 CDSGYRMTQRGRCEDIDECLNPSTCPDEQCVNSP--GSYQCVPCTEGFRGWNGQCLDVDE 716
C G C D CL+ D QC +P GS C+ C G+ G D+DE
Sbjct: 381 CPPGRTGL---LCHLEDMCLSQPCHGDAQCSTNPLTGSTLCL-CQPGYSGPTCH-QDLDE 435
Query: 717 CL----EPNVCAN-GDCSNLEGSYMCSCHKGYTRT---PDHKHCRDIDECQQGNLCVNGQ 768
CL P+ C + G C N GS+ C C GYT + DH C C G+ C+
Sbjct: 436 CLMAQQGPSPCEHGGSCLNTPGSFNCLCPPGYTGSRCEADHNECLS-QPCHPGSTCL--- 491
Query: 769 CKNTEGSFRCTCGQGYQLSAAKDQCE-DIDECQHRHLCAHGQCRNTEGSFQCVCDQGYRA 827
+ +F C C G + CE + +EC H C + FQC+C G+
Sbjct: 492 --DLLATFHCLCPPGLE----GQLCEVETNECASAPCLNHADCHDLLNGFQCICLPGFS- 544
Query: 828 SGLGDHC-EDINECLEDKSVCQRGDCINTAGSYDCTCPDGFQLDDNKTCQ-DINEC-EHP 884
G C EDI+EC G C + G++ C C GF + CQ +++EC P
Sbjct: 545 ---GTRCEEDIDEC-RSSPCANGGQCQDQPGAFHCKCLPGF---EGPRCQTEVDECLSDP 597
Query: 885 GLCGPQGECLNTEGSFHCVCQQGFSISADGRTCEDIDECVNNTVCDSHGFCDNTAGSFRC 944
C CL+ G+F C+C GF+ G+ CE + C N +C C + C
Sbjct: 598 --CPVGASCLDLPGAFFCLCPSGFT----GQLCE-VPLCAPN-LCQPKQICKDQKDKANC 649
Query: 945 LCYQGFQAPQDGQGCVDVNE-CELLSGVCGEAFCENVEGSFLCVCADENQEYSPMTGQCR 1003
LC P GC + C G C + C +C E G C
Sbjct: 650 LC------PDGSPGCAPPEDNCTCHHGHCQRSSC-------VCDVGWTGPECEAELGGCI 696
Query: 1004 SRTSTDLDVDVDQPKEEKKECYYNLNDASLCDNVLAPNVTKQECCCTSGAGWGDNCEIFP 1063
S QP C P +++ C SG P
Sbjct: 697 SAPCAHGGTCYPQPSGYNCTC---------PTGYTGPTCSEEMTACHSG----------P 737
Query: 1064 CPVLGTAEFTEMCPKGKGFVPAGESSSEAGGENYKDADECLLFGQEICKNGFCLNTRPG- 1122
C G+ C G S G + D C+ C NG RPG
Sbjct: 738 CLNGGS------CNPSPGGYYCTCPPSHTGPQCQTSTDYCV---SAPCFNGGTCVNRPGT 788
Query: 1123 YECYCKQGTYYDPVKLQCFDMDECQDP--SSCIDGQCVNTEGSYNCFCTHPMVLDASEKR 1180
+ C C G F C+ SC D C N + R
Sbjct: 789 FSCLCAMG----------FQGPRCEGKLRPSCADSPCRNRATCQD---------SPQGPR 829
Query: 1181 CIRPAESNEQIEETDVYQDLCWEHLSDEYVCSRPLVGKQTTYT-ECCCLYGEAWGMQCAL 1239
C+ P +T DLC + C R QT + C CL G W
Sbjct: 830 CLCPTGYTGGSCQT--LMDLC-----AQKPCPRNSHCLQTGPSFHCLCLQG--WTGPLCN 880
Query: 1240 CPLKDSDDYAQLCNIPVTGRRQPYGRDALVDFSEQYTPEADPYFIQDRFLNSFEELQAEE 1299
PL A I V+ G VD Y P F S +
Sbjct: 881 LPLSSCQKAALSQGIDVSSLCHNGG--LCVDSGPSYFCHCPP-----GFQGSLCQDHVNP 933
Query: 1300 CGILNGCENG-RCVRVQEGYTCDCFDGYHLDTAKMTCVDVNECDELNNRMSLCKNAKCIN 1358
C C+NG C+ GY C C GY D C + + C++ C N
Sbjct: 934 CE-SRPCQNGATCMAQPSGYLCQCAPGY----------DGQNC---SKELDACQSQPCHN 979
Query: 1359 ------TDGSYKCLCLPGYV 1372
G + C C PG+V
Sbjct: 980 HGTCTPKPGGFHCACPPGFV 999
Score = 185 bits (469), Expect = 3e-46
Identities = 175/646 (27%), Positives = 247/646 (38%), Gaps = 98/646 (15%)
Query: 543 PTQVTEINECTV---NPDICG-AGHCINLPVRYTCICYEGYRFSEQQRKCVDIDECTQVQ 598
PT +++EC + P C G C+N P + C+C GY S + D +EC +
Sbjct: 427 PTCHQDLDECLMAQQGPSPCEHGGSCLNTPGSFNCLCPPGYTGSRCE---ADHNEC--LS 481
Query: 599 HLCSQGR-CENTEGSFLCICPAGFMASEEGTNC-IDVDECLRPDVCGEGHCVNTVGAFRC 656
C G C + +F C+CP G EG C ++ +EC C + + F+C
Sbjct: 482 QPCHPGSTCLDLLATFHCLCPPGL----EGQLCEVETNECASAPCLNHADCHDLLNGFQC 537
Query: 657 EYCDSGYRMTQRGRCE-DIDECLNPSTCPDEQCVNSPGSYQCVPCTEGFRGWNGQCLDVD 715
C G+ T RCE DIDEC + QC + PG++ C C GF G Q +VD
Sbjct: 538 -ICLPGFSGT---RCEEDIDECRSSPCANGGQCQDQPGAFHC-KCLPGFEGPRCQT-EVD 591
Query: 716 ECLEPNVCANGDCSNLEGSYMCSCHKGYTRTPDHKHCRDIDECQQGNLCVNGQ-CKNTEG 774
ECL C +L G++ C C G+T ++ C NLC Q CK+ +
Sbjct: 592 ECLSDPCPVGASCLDLPGAFFCLCPSGFTG-----QLCEVPLCAP-NLCQPKQICKDQKD 645
Query: 775 SFRCTCGQGYQLSAAKDQCEDIDECQHRHLCAHGQCRNTEGSFQCVCDQGYRASGLGDHC 834
C C G A + D C C HG C+ + CVCD G+ G C
Sbjct: 646 KANCLCPDGSPGCAPPE-----DNCT----CHHGHCQRSS----CVCDVGWT----GPEC 688
Query: 835 E-DINECLEDKSVCQRGDCINTAGSYDCTCPDGFQLDDNKTCQDINECEHPGLCGPQGEC 893
E ++ C+ G C Y+CTCP G+ TC + H G C G C
Sbjct: 689 EAELGGCIS-APCAHGGTCYPQPSGYNCTCPTGYT---GPTCSEEMTACHSGPCLNGGSC 744
Query: 894 LNTEGSFHCVCQQGFSISADGRTCEDIDECVNNTVCDSHGFCDNTAGSFRCLCYQGFQAP 953
+ G ++C C S G C+ + + C + G C N G+F CLC GFQ P
Sbjct: 745 NPSPGGYYCTCPP----SHTGPQCQTSTDYCVSAPCFNGGTCVNRPGTFSCLCAMGFQGP 800
Query: 954 QDGQGCVDVNECE-LLSGVCGEAFCENVEGSFLCVCADENQEYSPM--TGQCRSRTSTDL 1010
+ CE L C ++ C N C D Q + TG T +
Sbjct: 801 R----------CEGKLRPSCADSPCRN-----RATCQDSPQGPRCLCPTGYTGGSCQTLM 845
Query: 1011 DVDVDQPKEEKKECYYNLNDASLCDNVLAPNVTKQECCCTSG-AGWGDNCEIFPCPVLGT 1069
D+ +P C P+ C C G G N + C
Sbjct: 846 DLCAQKPCPRNSHCLQT-----------GPSF---HCLCLQGWTGPLCNLPLSSCQKAAL 891
Query: 1070 A---EFTEMCPKGKGFVPAGES---SSEAGGENYKDADECLLFGQEICKNG-FCLNTRPG 1122
+ + + +C G V +G S G + D C+NG C+ G
Sbjct: 892 SQGIDVSSLCHNGGLCVDSGPSYFCHCPPGFQGSLCQDHVNPCESRPCQNGATCMAQPSG 951
Query: 1123 YECYCKQGTYYDPVKLQCFDMDECQDPSSCIDGQCVNTEGSYNCFC 1168
Y C C G YD ++D CQ G C G ++C C
Sbjct: 952 YLCQCAPG--YDGQNCS-KELDACQSQPCHNHGTCTPKPGGFHCAC 994
Score = 161 bits (407), Expect = 5e-39
Identities = 307/1285 (23%), Positives = 438/1285 (34%), Gaps = 325/1285 (25%)
Query: 80 PCMNGGQCSS----RDKCQCPPNFTGKLCQIPVHGASVPKLYQHSQQPGKALGTHVIHST 135
PC NGG C S + CQC P F G+ CQ P +L Q+ L + +
Sbjct: 34 PCANGGTCLSLSLGQGTCQCAPGFLGETCQFP-DPCQNAQLCQNGGSCQALLPAPLGLPS 92
Query: 136 HTLPLTVT-------------SQQGVKVKFPPNIVNIHVKHPPEASVQIHQVSRIDGPTG 182
PLT + Q ++ PP+ + + +AS + Q S + G TG
Sbjct: 93 SPSPLTPSFLCTCLPGFTGERCQAKLEDPCPPSFCSKRGRCHIQASGR-PQCSCMPGWTG 151
Query: 183 QKTKEAQPGQSQVSYQGLPVQKTQTIHSTYSHQQ--VIPHVYPVAAKTQLGRCFQE---- 236
++ Q + P +TY Q P A + + CFQ+
Sbjct: 152 EQC------QLRDFCSANPCVNGGVCLATYPQIQCHCPPGFEGHACERDVNECFQDPGPC 205
Query: 237 --------TIGS-QC----GKALPGLSKQEDCCGTVGTSWGFNKCQKCPKKPS-YHGYNQ 282
T+GS QC G+ P + C G S G CQ P+K S +H
Sbjct: 206 PKGTSCHNTLGSFQCLCPVGQEGPRCELRAGPCPPRGCSNG-GTCQLMPEKDSTFH---- 260
Query: 283 MMECLPGY---------------KRVNNTFCQ---------------------DINECQL 306
+ C PG+ + N CQ D++EC+
Sbjct: 261 LCLCPPGFIGPDCEVNPDNCVSHQCQNGGTCQDGLDTYTCLCPETWTGWDCSEDVDECET 320
Query: 307 QGV--CPN-GECLNTMGSYRCTCKIGFG--------PDPTFSSCVPDPPVISEEKGPCYR 355
QG C N G C N+ GS+ C C G+G D ++C P I + G
Sbjct: 321 QGPPHCRNGGTCQNSAGSFHCVCVSGWGGTSCEENLDDCIAATCAPGSTCI-DRVGSFSC 379
Query: 356 LVSSGRQCMHPLSVHLTKQLCCCSVGKAWGPHCEKCPLPGTAAFKEICPGGMGYTVSGVH 415
L GR L HL C S C PL G+ +C GY+ H
Sbjct: 380 LCPPGRT---GLLCHLEDM--CLSQPCHGDAQCSTNPLTGST----LCLCQPGYSGPTCH 430
Query: 416 RRRPIHHHVGKGPVFVKP----KNTQPVAKSTHPPPLPAKE-EPVEALTFSREHGPGVAE 470
+ +GP + NT PP E S+ PG
Sbjct: 431 QDLDECLMAQQGPSPCEHGGSCLNTPGSFNCLCPPGYTGSRCEADHNECLSQPCHPGSTC 490
Query: 471 PEVATAPPEKEIPSLDQEKTKLEPGQPQLSPGISTIHLHPQFPG---IVIEKTSPPVPVE 527
++ P L+ + ++E + +P ++ H G I + S E
Sbjct: 491 LDLLATFHCLCPPGLEGQLCEVETNECASAPCLNHADCHDLLNGFQCICLPGFSGTRCEE 550
Query: 528 VAPEASTSSASQVIAPTQVTEINECTVNPDICGAGHCINLPVRYTCICYEGYRFSEQQRK 587
E +S + +C P GA HC LP +EG R
Sbjct: 551 DIDECRSSPCANG---------GQCQDQP---GAFHCKCLP------GFEGPRCQ----- 587
Query: 588 CVDIDECTQVQHLCSQG-RCENTEGSFLCICPAGFMA---------------------SE 625
++DEC + C G C + G+F C+CP+GF +
Sbjct: 588 -TEVDEC--LSDPCPVGASCLDLPGAFFCLCPSGFTGQLCEVPLCAPNLCQPKQICKDQK 644
Query: 626 EGTNCIDVD---ECLRPD---VCGEGHCVNTVGAFRCEYCDSGYRMTQRGRCE-DIDECL 678
+ NC+ D C P+ C GHC + C CD G+ + CE ++ C+
Sbjct: 645 DKANCLCPDGSPGCAPPEDNCTCHHGHCQRS----SC-VCDVGWTGPE---CEAELGGCI 696
Query: 679 NPSTCPDEQCVNSPGSYQCVPCTEGFRGWNGQCLDVDECLEPNVCAN-GDCSNLEGSYMC 737
+ C P Y C C G+ G C + C N G C+ G Y C
Sbjct: 697 SAPCAHGGTCYPQPSGYNCT-CPTGYTG--PTCSEEMTACHSGPCLNGGSCNPSPGGYYC 753
Query: 738 SCHKGYTRTPDHKHCR-DIDECQQGNLCVNGQCKNTEGSFRCTCGQGYQ---------LS 787
+C +T C+ D C G C N G+F C C G+Q S
Sbjct: 754 TCPPSHT----GPQCQTSTDYCVSAPCFNGGTCVNRPGTFSCLCAMGFQGPRCEGKLRPS 809
Query: 788 AAKDQCEDIDECQH-----RHLCAHG----------------------QCRNTEGSFQCV 820
A C + CQ R LC G C T SF C+
Sbjct: 810 CADSPCRNRATCQDSPQGPRCLCPTGYTGGSCQTLMDLCAQKPCPRNSHCLQTGPSFHCL 869
Query: 821 CDQGYRASGLG---DHCED--INECLEDKSVCQRGD-CINTAGSYDCTCPDGFQLDDNKT 874
C QG+ C+ +++ ++ S+C G C+++ SY C CP GFQ
Sbjct: 870 CLQGWTGPLCNLPLSSCQKAALSQGIDVSSLCHNGGLCVDSGPSYFCHCPPGFQ---GSL 926
Query: 875 CQD-INECEHPGLCGPQGECLNTEGSFHCVCQQGFSISADGRTC-EDIDECVNNTVCDSH 932
CQD +N CE C C+ + C C G+ DG+ C +++D C + C +H
Sbjct: 927 CQDHVNPCESRP-CQNGATCMAQPSGYLCQCAPGY----DGQNCSKELDAC-QSQPCHNH 980
Query: 933 GFCDNTAGSFRCLCYQGFQAPQDGQGCV-DVNECELLSGVC---GEAFCENVEGSFLCVC 988
G C G F C C GF G C DV+EC L C G A C ++ +F C C
Sbjct: 981 GTCTPKPGGFHCACPPGFV----GLRCEGDVDEC--LDQPCHPTGTAACHSLANAFYCQC 1034
Query: 989 ADENQEYSPMTGQCRSRTSTDLDVDVDQPKEEKKECYYNLNDASLCDNVLAPNVTKQECC 1048
+ G ++D QP C++ C
Sbjct: 1035 ---------LPGHTGQWCEVEIDPCHSQP------CFHG-----------------GTCE 1062
Query: 1049 CTSGAGWGDNCEIFPCPVLGTAEFTEMCPKGKGFVPAGESSSEAGGENYKDADECLLFGQ 1108
T+G+ G C CPKG G + S A C G
Sbjct: 1063 ATAGSPLGFICH---------------CPKGF----EGPTCSHR-------APSC---GF 1093
Query: 1109 EICKN-GFCL-NTRPGY--ECYCKQGTYYDPVKLQCFDMDECQDPSSCI-DGQCVNTEG- 1162
C + G CL + +PG+ C C G Y P L C PS C+ +G C T G
Sbjct: 1094 HHCHHGGLCLPSPKPGFPPRCACLSG-YGGPDCLTPPAPKGCGPPSPCLYNGSCSETTGL 1152
Query: 1163 ---SYNCFCTHPMVLDASEKRCIRP 1184
+ C C H + RC +P
Sbjct: 1153 GGPGFRCSCPH----SSPGPRCQKP 1173
Score = 143 bits (361), Expect = 1e-33
Identities = 222/892 (24%), Positives = 310/892 (34%), Gaps = 232/892 (26%)
Query: 552 CTVNPDICG-AGHCINLPV-RYTCICYEGYRFSEQQRKCVDIDECTQVQHLCSQGRCENT 609
C P+ C G C++L + + TC C G+ C D C Q + G C+
Sbjct: 28 CGSFPEPCANGGTCLSLSLGQGTCQCAPGFL----GETCQFPDPCQNAQLCQNGGSCQAL 83
Query: 610 --------------EGSFLCICPAGFMASEEGTNCIDVDECLRPDVCGEGHCVNTVGAFR 655
SFLC C GF G C + D C C
Sbjct: 84 LPAPLGLPSSPSPLTPSFLCTCLPGFT----GERC----QAKLEDPCPPSFC-------- 127
Query: 656 CEYCDSGYRMTQRGRCEDIDECLNPSTCPDEQCVNSPGSYQCVPCTEGFRGWNGQCLDVD 715
++RGRC + S P QC C+P GW G+ +
Sbjct: 128 ----------SKRGRCH-----IQASGRP--QC-------SCMP------GWTGEQCQLR 157
Query: 716 ECLEPNVCANGD-CSNLEGSYMCSCHKGYTRTPDHKHCRDIDEC-QQGNLCVNG-QCKNT 772
+ N C NG C C C G+ H RD++EC Q C G C NT
Sbjct: 158 DFCSANPCVNGGVCLATYPQIQCHCPPGFE---GHACERDVNECFQDPGPCPKGTSCHNT 214
Query: 773 EGSFRCTCGQGYQLSAAKDQCE-DIDECQHRHLCAHGQCR---NTEGSFQ-CVCDQGYRA 827
GSF+C C G + +CE C R G C+ + +F C+C G+
Sbjct: 215 LGSFQCLCPVGQE----GPRCELRAGPCPPRGCSNGGTCQLMPEKDSTFHLCLCPPGF-- 268
Query: 828 SGLGDHCE-DINECLEDKSVCQRGD-CINTAGSYDCTCPDGFQLDDNKTCQDINECEHPG 885
+G CE + + C+ + CQ G C + +Y C CP+ + D +D++ECE G
Sbjct: 269 --IGPDCEVNPDNCVSHQ--CQNGGTCQDGLDTYTCLCPETWTGWD--CSEDVDECETQG 322
Query: 886 L--CGPQGECLNTEGSFHCVCQQGFSISADGRTCED-IDECVNNTVCDSHGFCDNTAGSF 942
C G C N+ GSFHCVC G+ G +CE+ +D+C+ T C C + GSF
Sbjct: 323 PPHCRNGGTCQNSAGSFHCVCVSGWG----GTSCEENLDDCIAAT-CAPGSTCIDRVGSF 377
Query: 943 RCLCYQGFQAPQDGQGCVDVNECELLSGVC-GEAFCEN--VEGSFLCVCADENQEYSPMT 999
CLC G + G C + C LS C G+A C + GS LC+C
Sbjct: 378 SCLCPPG----RTGLLCHLEDMC--LSQPCHGDAQCSTNPLTGSTLCLC---------QP 422
Query: 1000 GQCRSRTSTDLDVDV-----DQPKEEKKECYYNLNDASLCDNVLAPNVTKQECCCTSGAG 1054
G DLD + P E C LN + + P T C
Sbjct: 423 GYSGPTCHQDLDECLMAQQGPSPCEHGGSC---LNTPGSFNCLCPPGYTGSRCEADH--- 476
Query: 1055 WGDNCEIFPCPVLGT-----AEFTEMCPKG-KGFVPAGESSSEAGGENYKDADECLLFGQ 1108
+ C PC T A F +CP G +G + E++ A AD
Sbjct: 477 --NECLSQPCHPGSTCLDLLATFHCLCPPGLEGQLCEVETNECASAPCLNHAD------- 527
Query: 1109 EICKNGFCLNTRPGYECYCKQGTYYDPVKLQCFDMDECQDPSSCIDGQCVNTEGSYNCFC 1168
C + G++C C G + + + D+DEC+ GQC + G+++C C
Sbjct: 528 -------CHDLLNGFQCICLPG--FSGTRCE-EDIDECRSSPCANGGQCQDQPGAFHCKC 577
Query: 1169 THPMVLDASEKRCIRPAESNEQIEETDVYQDLCWEHLSDEYVCSRPLVGKQTTYTECCCL 1228
+ RC Q E + D C C L
Sbjct: 578 ----LPGFEGPRC--------QTEVDECLSDPC------------------PVGASCLDL 607
Query: 1229 YGEAWGMQCALCPLKDSDDYAQLCNIPVTGRRQPYGRDALVDFSEQ---YTPEADPYFI- 1284
G + LCP S QLC +P+ + D ++ P+ P
Sbjct: 608 PGAFF----CLCP---SGFTGQLCEVPLCAPNLCQPKQICKDQKDKANCLCPDGSPGCAP 660
Query: 1285 -QDRFLNSFEELQAEEC------------GILNGC------ENGRCVRVQEGYTCDCFDG 1325
+D Q C L GC G C GY C C G
Sbjct: 661 PEDNCTCHHGHCQRSSCVCDVGWTGPECEAELGGCISAPCAHGGTCYPQPSGYNCTCPTG 720
Query: 1326 YHLDTAKMTCVDVNECDELNNRMSLCKNAKCIN------TDGSYKCLCLPGY 1371
Y T C E M+ C + C+N + G Y C C P +
Sbjct: 721 YTGPT----------CSE---EMTACHSGPCLNGGSCNPSPGGYYCTCPPSH 759
Score = 130 bits (328), Expect = 7e-30
Identities = 180/715 (25%), Positives = 257/715 (35%), Gaps = 162/715 (22%)
Query: 720 PNVCANGD-CSNLE-GSYMCSCHKGYTRTPDHKHCRDIDECQQGNLCVNG-QCKNT---- 772
P CANG C +L G C C G+ + C+ D CQ LC NG C+
Sbjct: 32 PEPCANGGTCLSLSLGQGTCQCAPGFLG----ETCQFPDPCQNAQLCQNGGSCQALLPAP 87
Query: 773 ----------EGSFRCTCGQGYQLSAAKDQCEDIDECQHRHLCAHGQCR-NTEGSFQCVC 821
SF CTC G+ + + ED C G+C G QC C
Sbjct: 88 LGLPSSPSPLTPSFLCTCLPGFTGERCQAKLED--PCPPSFCSKRGRCHIQASGRPQCSC 145
Query: 822 DQGYRASGLGDHCEDINECLEDKSVCQRGDCINTAGSYDCTCPDGFQLDDNKTCQ-DINE 880
G+ G+ C+ + C + V G C+ T C CP GF+ C+ D+NE
Sbjct: 146 MPGWT----GEQCQLRDFCSANPCV-NGGVCLATYPQIQCHCPPGFE---GHACERDVNE 197
Query: 881 C-EHPGLCGPQGECLNTEGSFHCVCQQGFSISADGRTCEDIDECVNNTVCDSHGFC---- 935
C + PG C C NT GSF C+C G +G CE C + G C
Sbjct: 198 CFQDPGPCPKGTSCHNTLGSFQCLCPVG----QEGPRCELRAGPCPPRGCSNGGTCQLMP 253
Query: 936 DNTAGSFRCLCYQGFQAPQDGQGCVDVNECELLSGVCGEA-FCENVEGSFLCVCADENQE 994
+ + CLC GF P +VN +S C C++ ++ C+C +
Sbjct: 254 EKDSTFHLCLCPPGFIGPD-----CEVNPDNCVSHQCQNGGTCQDGLDTYTCLCPE---- 304
Query: 995 YSPMTGQCRSRTSTDLDVDVDQPKEEKKECYYNLNDASLCDNVLAPNVTKQECCCTSGAG 1054
+ T D DVD+ + + + + C N + C C SG
Sbjct: 305 ---------TWTGWDCSEDVDECETQGPP---HCRNGGTCQN----SAGSFHCVCVSG-- 346
Query: 1055 WG--------DNCEIFPCPVLGTA-----EFTEMCPKGKGFVPAGESSSEAGGENYKDAD 1101
WG D+C C T F+ +CP G+ G D
Sbjct: 347 WGGTSCEENLDDCIAATCAPGSTCIDRVGSFSCLCPPGRT------------GLLCHLED 394
Query: 1102 ECLLFGQEICKNGFCLNTRP---GYECYCKQGTYYDPVKLQCFDMDEC----QDPSSCID 1154
CL + C +T P C C+ G Y P Q D+DEC Q PS C
Sbjct: 395 MCL---SQPCHGDAQCSTNPLTGSTLCLCQPG-YSGPTCHQ--DLDECLMAQQGPSPCEH 448
Query: 1155 G-QCVNTEGSYNCFCTHPMVLDASEKRCIRPAESNEQIEETDVYQDLCWEHLSDEYVCSR 1213
G C+NT GS+NC C + RC A+ NE + + C + L+ +
Sbjct: 449 GGSCLNTPGSFNCLCPPGY----TGSRC--EADHNECLSQPCHPGSTCLDLLATFHCLCP 502
Query: 1214 PLVGKQTTYTECCCLYGEAWGMQCALCPLKDSDDYAQLCNIPVTGRRQPYGRDALVDFSE 1273
P + Q E +CA P + D L N
Sbjct: 503 PGLEGQLCEVET---------NECASAPCLNHADCHDLLN-------------------- 533
Query: 1274 QYTPEADPYFIQDRFLNSFEELQAEECGILNGCENGRCVRVQEGYTCDCFDGYHLDTAKM 1333
+ P F R +E ++ C NG G+C + C C G+ +
Sbjct: 534 GFQCICLPGFSGTRCEEDIDECRSSPCA--NG---GQCQDQPGAFHCKCLPGFEGPRCQ- 587
Query: 1334 TCVDVNECDELNNRMSLCKNAKCINTDGSYKCLCLPGY------VPSDKPNYCTP 1382
+V+EC L++ + A C++ G++ CLC G+ VP PN C P
Sbjct: 588 --TEVDEC--LSDPCPV--GASCLDLPGAFFCLCPSGFTGQLCEVPLCAPNLCQP 636
Score = 36.6 bits (83), Expect = 0.17
Identities = 16/33 (48%), Positives = 19/33 (57%), Gaps = 4/33 (12%)
Query: 77 CHL-PCMNGGQCSSRDK---CQCPPNFTGKLCQ 105
CH PC+NGG C+ C CPP+ TG CQ
Sbjct: 733 CHSGPCLNGGSCNPSPGGYYCTCPPSHTGPQCQ 765
Score = 31.2 bits (69), Expect = 7.3
Identities = 28/86 (32%), Positives = 31/86 (36%), Gaps = 29/86 (33%)
Query: 42 GSCQNS-------CEKGNTTTLISENGHAADTLTATNFRVVICHLPCMNGGQCSSRD--- 91
G+CQNS C G T EN D + AT C G C R
Sbjct: 330 GTCQNSAGSFHCVCVSGWGGTSCEEN--LDDCIAAT----------CAPGSTCIDRVGSF 377
Query: 92 KCQCPPNFTGKLCQI-------PVHG 110
C CPP TG LC + P HG
Sbjct: 378 SCLCPPGRTGLLCHLEDMCLSQPCHG 403
>gi|169178458 PREDICTED: hemicentin 2 [Homo sapiens]
Length = 3874
Score = 203 bits (516), Expect = 1e-51
Identities = 129/329 (39%), Positives = 161/329 (48%), Gaps = 45/329 (13%)
Query: 575 CYEGYRFSEQQRKCVDIDECTQVQHLCSQGRCENTEGSFLCICPAGFMASEEGTNCIDVD 634
C EG+ Q CVD DEC+ CS C N G F C CP GF + + NC DVD
Sbjct: 3428 CPEGFELDSQGAFCVDRDECSGGPSPCSHA-CLNAPGRFSCTCPTGFALAWDDRNCRDVD 3486
Query: 635 ECL-RPDVCGEG-HCVNTVGAFRC-EYCDSGYRMTQRGRCEDIDECLNP-STCPDEQ-CV 689
EC +C EG CVN +G++RC C G+R+ CED+DECL C Q C
Sbjct: 3487 ECAWDAHLCREGQRCVNLLGSYRCLPDCGPGFRVADGAGCEDVDECLEGLDDCHYNQLCE 3546
Query: 690 NSPGSYQCVPCTEGFR--GWNGQCLDVDECLE-PNVCANGDCSNLEGSYMCSCHKGYTRT 746
N+PG ++C C G+R G + CLDV+ECL+ P CA C NL+GSY C C G T
Sbjct: 3547 NTPGGHRC-SCPRGYRMQGPSLPCLDVNECLQLPKACAY-QCHNLQGSYRCLCPPGQTLL 3604
Query: 747 PDHKHCRDIDECQQGNLCVN----------------GQCKNTEGSF-----------RCT 779
D K C ++ Q V+ G + S R
Sbjct: 3605 RDGKACTSLERNGQNVTTVSHRGPLLPWLRPWASIPGTSYHAWVSLRPGPMALSSVGRAW 3664
Query: 780 CGQGYQLSAAKDQCEDIDECQHRHLCAHGQCRNTEGSFQCVCDQGYRASGLGDHCEDINE 839
C G+ C D+DEC+ R+LC H CRNTEGS+QC+C GYR G +C+DINE
Sbjct: 3665 CPPGF--IRQNGVCTDLDECRVRNLCQHA-CRNTEGSYQCLCPAGYRLLPSGKNCQDINE 3721
Query: 840 CLEDKSVCQRGD-CINTAGSYDCT---CP 864
C E+ C G C NT GSY C CP
Sbjct: 3722 CEEESIECGPGQMCFNTRGSYQCVDTPCP 3750
Score = 177 bits (448), Expect = 8e-44
Identities = 125/353 (35%), Positives = 162/353 (45%), Gaps = 50/353 (14%)
Query: 698 VPCTEGFR--GWNGQCLDVDECLE-PNVCANGDCSNLEGSYMCSCHKGYTRTPDHKHCRD 754
V C EGF C+D DEC P+ C++ C N G + C+C G+ D ++CRD
Sbjct: 3426 VGCPEGFELDSQGAFCVDRDECSGGPSPCSHA-CLNAPGRFSCTCPTGFALAWDDRNCRD 3484
Query: 755 IDECQ-QGNLCVNGQ-CKNTEGSFRCT--CGQGYQLSAAKDQCEDIDEC-QHRHLCAHGQ 809
+DEC +LC GQ C N GS+RC CG G++++ CED+DEC + C + Q
Sbjct: 3485 VDECAWDAHLCREGQRCVNLLGSYRCLPDCGPGFRVADGAG-CEDVDECLEGLDDCHYNQ 3543
Query: 810 -CRNTEGSFQCVCDQGYRASGLGDHCEDINECLEDKSVCQRGDCINTAGSYDCTCPDGFQ 868
C NT G +C C +GYR G C D+NECL+ C C N GSY C CP G
Sbjct: 3544 LCENTPGGHRCSCPRGYRMQGPSLPCLDVNECLQLPKACAY-QCHNLQGSYRCLCPPGQT 3602
Query: 869 L-DDNKTC-------QDINECEHPG---------------------LCGPQGECLNTEGS 899
L D K C Q++ H G P L++ G
Sbjct: 3603 LLRDGKACTSLERNGQNVTTVSHRGPLLPWLRPWASIPGTSYHAWVSLRPGPMALSSVG- 3661
Query: 900 FHCVCQQGFSISADGRTCEDIDECVNNTVCDSHGFCDNTAGSFRCLCYQGFQAPQDGQGC 959
C GF I +G C D+DEC +C C NT GS++CLC G++ G+ C
Sbjct: 3662 -RAWCPPGF-IRQNG-VCTDLDECRVRNLCQHA--CRNTEGSYQCLCPAGYRLLPSGKNC 3716
Query: 960 VDVNECELLSGVCGEA-FCENVEGSFLCVCADENQEY--SPMTGQCRSRTSTD 1009
D+NECE S CG C N GS+ CV Y P G C R S D
Sbjct: 3717 QDINECEEESIECGPGQMCFNTRGSYQCVDTPCPATYRQGPSPGTCFRRCSQD 3769
Score = 172 bits (436), Expect = 2e-42
Identities = 111/325 (34%), Positives = 158/325 (48%), Gaps = 45/325 (13%)
Query: 659 CDSGYRMTQRGR-CEDIDECLN-PSTCPDEQCVNSPGSYQCVPCTEGFR-GWNGQ-CLDV 714
C G+ + +G C D DEC PS C C+N+PG + C C GF W+ + C DV
Sbjct: 3428 CPEGFELDSQGAFCVDRDECSGGPSPC-SHACLNAPGRFSCT-CPTGFALAWDDRNCRDV 3485
Query: 715 DECL-EPNVCANGD-CSNLEGSYMC--SCHKGYTRTPDHKHCRDIDECQQG--NLCVNGQ 768
DEC + ++C G C NL GSY C C G+ R D C D+DEC +G + N
Sbjct: 3486 DECAWDAHLCREGQRCVNLLGSYRCLPDCGPGF-RVADGAGCEDVDECLEGLDDCHYNQL 3544
Query: 769 CKNTEGSFRCTCGQGYQLSAAKDQCEDIDEC-QHRHLCAHGQCRNTEGSFQCVCDQGYRA 827
C+NT G RC+C +GY++ C D++EC Q CA+ QC N +GS++C+C G
Sbjct: 3545 CENTPGGHRCSCPRGYRMQGPSLPCLDVNECLQLPKACAY-QCHNLQGSYRCLCPPGQTL 3603
Query: 828 SGLGDHCEDINECLED-KSVCQRGDCIN--------TAGSYDCT---------------- 862
G C + ++ +V RG + SY
Sbjct: 3604 LRDGKACTSLERNGQNVTTVSHRGPLLPWLRPWASIPGTSYHAWVSLRPGPMALSSVGRA 3663
Query: 863 -CPDGFQLDDNKTCQDINECEHPGLCGPQGECLNTEGSFHCVCQQGFSISADGRTCEDID 921
CP GF + N C D++EC LC Q C NTEGS+ C+C G+ + G+ C+DI+
Sbjct: 3664 WCPPGF-IRQNGVCTDLDECRVRNLC--QHACRNTEGSYQCLCPAGYRLLPSGKNCQDIN 3720
Query: 922 ECVNNTV-CDSHGFCDNTAGSFRCL 945
EC ++ C C NT GS++C+
Sbjct: 3721 ECEEESIECGPGQMCFNTRGSYQCV 3745
Score = 172 bits (435), Expect = 3e-42
Identities = 117/325 (36%), Positives = 152/325 (46%), Gaps = 45/325 (13%)
Query: 617 CPAGFMASEEGTNCIDVDECLR-PDVCGEGHCVNTVGAFRCEYCDSGYRMTQRGR-CEDI 674
CP GF +G C+D DEC P C C+N G F C C +G+ + R C D+
Sbjct: 3428 CPEGFELDSQGAFCVDRDECSGGPSPCSHA-CLNAPGRFSCT-CPTGFALAWDDRNCRDV 3485
Query: 675 DECL-NPSTCPDEQ-CVNSPGSYQCVP-CTEGFRGWNGQ-CLDVDECLE--PNVCANGDC 728
DEC + C + Q CVN GSY+C+P C GFR +G C DVDECLE + N C
Sbjct: 3486 DECAWDAHLCREGQRCVNLLGSYRCLPDCGPGFRVADGAGCEDVDECLEGLDDCHYNQLC 3545
Query: 729 SNLEGSYMCSCHKGYTRTPDHKHCRDIDECQQGNLCVNGQCKNTEGSFRCTCGQGYQLSA 788
N G + CSC +GY C D++EC Q QC N +GS+RC C G L
Sbjct: 3546 ENTPGGHRCSCPRGYRMQGPSLPCLDVNECLQLPKACAYQCHNLQGSYRCLCPPGQTLLR 3605
Query: 789 AKDQC-------EDIDECQHRH--------------LCAHGQCRNTEGSF------QCVC 821
C +++ HR H G + C
Sbjct: 3606 DGKACTSLERNGQNVTTVSHRGPLLPWLRPWASIPGTSYHAWVSLRPGPMALSSVGRAWC 3665
Query: 822 DQGY-RASGLGDHCEDINECLEDKSVCQRGDCINTAGSYDCTCPDGFQ-LDDNKTCQDIN 879
G+ R +G+ C D++EC +++CQ C NT GSY C CP G++ L K CQDIN
Sbjct: 3666 PPGFIRQNGV---CTDLDEC-RVRNLCQHA-CRNTEGSYQCLCPAGYRLLPSGKNCQDIN 3720
Query: 880 ECEHPGL-CGPQGECLNTEGSFHCV 903
ECE + CGP C NT GS+ CV
Sbjct: 3721 ECEEESIECGPGQMCFNTRGSYQCV 3745
Score = 161 bits (408), Expect = 4e-39
Identities = 119/336 (35%), Positives = 157/336 (46%), Gaps = 53/336 (15%)
Query: 550 NECTVNPDICGAGHCINLPVRYTCICYEGYRFSEQQRKCVDIDECTQVQHLCSQG-RCEN 608
+EC+ P C C+N P R++C C G+ + R C D+DEC HLC +G RC N
Sbjct: 3445 DECSGGPSPCSHA-CLNAPGRFSCTCPTGFALAWDDRNCRDVDECAWDAHLCREGQRCVN 3503
Query: 609 TEGSFLCI--CPAGFMASEEGTNCIDVDECLRP-DVCGEGH-CVNTVGAFRCEYCDSGYR 664
GS+ C+ C GF + +G C DVDECL D C C NT G RC C GYR
Sbjct: 3504 LLGSYRCLPDCGPGFRVA-DGAGCEDVDECLEGLDDCHYNQLCENTPGGHRCS-CPRGYR 3561
Query: 665 MTQRG-RCEDIDECLN-PSTCPDEQCVNSPGSYQCV------------PCTEGFRGWNGQ 710
M C D++ECL P C QC N GSY+C+ CT R NGQ
Sbjct: 3562 MQGPSLPCLDVNECLQLPKACA-YQCHNLQGSYRCLCPPGQTLLRDGKACTSLER--NGQ 3618
Query: 711 CLDVDECLEPNVCANGDCSNLEG-SY-----------------MCSCHKGYTRTPDHKHC 752
+ P + +++ G SY C G+ R + C
Sbjct: 3619 NVTTVSHRGPLLPWLRPWASIPGTSYHAWVSLRPGPMALSSVGRAWCPPGFIR--QNGVC 3676
Query: 753 RDIDECQQGNLCVNGQCKNTEGSFRCTCGQGYQLSAAKDQCEDIDECQHRHL-CAHGQ-C 810
D+DEC+ NLC + C+NTEGS++C C GY+L + C+DI+EC+ + C GQ C
Sbjct: 3677 TDLDECRVRNLCQHA-CRNTEGSYQCLCPAGYRLLPSGKNCQDINECEEESIECGPGQMC 3735
Query: 811 RNTEGSFQCV---CDQGYRASGLGDHCEDINECLED 843
NT GS+QCV C YR C C +D
Sbjct: 3736 FNTRGSYQCVDTPCPATYRQGPSPGTC--FRRCSQD 3769
Score = 144 bits (363), Expect = 6e-34
Identities = 100/319 (31%), Positives = 143/319 (44%), Gaps = 50/319 (15%)
Query: 739 CHKGYTRTPDHKHCRDIDECQQGNLCVNGQCKNTEGSFRCTCGQGYQLSAAKDQCEDIDE 798
C +G+ C D DEC G + C N G F CTC G+ L+ C D+DE
Sbjct: 3428 CPEGFELDSQGAFCVDRDECSGGPSPCSHACLNAPGRFSCTCPTGFALAWDDRNCRDVDE 3487
Query: 799 CQ-HRHLCAHGQ-CRNTEGSFQCV--CDQGYRASGLGDHCEDINECLEDKSVCQRGD-CI 853
C HLC GQ C N GS++C+ C G+R + G CED++ECLE C C
Sbjct: 3488 CAWDAHLCREGQRCVNLLGSYRCLPDCGPGFRVAD-GAGCEDVDECLEGLDDCHYNQLCE 3546
Query: 854 NTAGSYDCTCPDGFQLDD-NKTCQDINEC-EHPGLCGPQGECLNTEGSFHCVCQQGFSIS 911
NT G + C+CP G+++ + C D+NEC + P C Q C N +GS+ C+C G ++
Sbjct: 3547 NTPGGHRCSCPRGYRMQGPSLPCLDVNECLQLPKACAYQ--CHNLQGSYRCLCPPGQTLL 3604
Query: 912 ADGRTCEDIDECVNNTVCDSH---------GFCDNTAGSF-----------------RCL 945
DG+ C ++ N SH + S+ R
Sbjct: 3605 RDGKACTSLERNGQNVTTVSHRGPLLPWLRPWASIPGTSYHAWVSLRPGPMALSSVGRAW 3664
Query: 946 CYQGFQAPQDGQGCVDVNECELLSGVCGEAFCENVEGSFLCVCADENQEYSPMTGQCRSR 1005
C GF Q+G C D++EC + +C A C N EGS+ C+C P C+
Sbjct: 3665 CPPGF-IRQNGV-CTDLDECR-VRNLCQHA-CRNTEGSYQCLC-PAGYRLLPSGKNCQ-- 3717
Query: 1006 TSTDLDVDVDQPKEEKKEC 1024
D+++ +EE EC
Sbjct: 3718 -------DINECEEESIEC 3729
Score = 125 bits (313), Expect = 4e-28
Identities = 104/333 (31%), Positives = 141/333 (42%), Gaps = 39/333 (11%)
Query: 863 CPDGFQLDDNKT-CQDINECEH-PGLCGPQGECLNTEGSFHCVCQQGFSISADGRTCEDI 920
CP+GF+LD C D +EC P C CLN G F C C GF+++ D R C D+
Sbjct: 3428 CPEGFELDSQGAFCVDRDECSGGPSPCSHA--CLNAPGRFSCTCPTGFALAWDDRNCRDV 3485
Query: 921 DECVNNT-VCDSHGFCDNTAGSFRCL--CYQGFQAPQDGQGCVDVNEC-ELLSGVCGEAF 976
DEC + +C C N GS+RCL C GF+ DG GC DV+EC E L
Sbjct: 3486 DECAWDAHLCREGQRCVNLLGSYRCLPDCGPGFRVA-DGAGCEDVDECLEGLDDCHYNQL 3544
Query: 977 CENVEGSFLCVCADENQEYSPMTGQCRSRTSTDLDVDVDQPKEEKKECYYNLNDASLCDN 1036
CEN G C C + P S D++ + PK +C+ NL + C
Sbjct: 3545 CENTPGGHRCSCPRGYRMQGP------SLPCLDVNECLQLPKACAYQCH-NLQGSYRCLC 3597
Query: 1037 VLAPNVTKQECCCTSGAGWGDNCE-------IFP-----CPVLGTA--EFTEMCPKGKGF 1082
+ + CTS G N + P + GT+ + + P
Sbjct: 3598 PPGQTLLRDGKACTSLERNGQNVTTVSHRGPLLPWLRPWASIPGTSYHAWVSLRPGPMAL 3657
Query: 1083 VPAGESSSEAGGENYK----DADECLLFGQEICKNGFCLNTRPGYECYCKQGTYYDPVKL 1138
G + G D DEC + + +C++ C NT Y+C C G P
Sbjct: 3658 SSVGRAWCPPGFIRQNGVCTDLDECRV--RNLCQHA-CRNTEGSYQCLCPAGYRLLPSGK 3714
Query: 1139 QCFDMDECQDPS-SCIDGQ-CVNTEGSYNCFCT 1169
C D++EC++ S C GQ C NT GSY C T
Sbjct: 3715 NCQDINECEEESIECGPGQMCFNTRGSYQCVDT 3747
Score = 100 bits (248), Expect = 1e-20
Identities = 76/255 (29%), Positives = 111/255 (43%), Gaps = 50/255 (19%)
Query: 548 EINECTVNPDICGAGH-CINLPVRYTCICYEGYRFSEQQRKCVDIDECTQVQHLCSQGRC 606
+++EC D C C N P + C C GYR C+D++EC Q+ C+ +C
Sbjct: 3528 DVDECLEGLDDCHYNQLCENTPGGHRCSCPRGYRMQGPSLPCLDVNECLQLPKACAY-QC 3586
Query: 607 ENTEGSFLCICPAGFMASEEGTNCIDVDE----------------CLRP--DVCGEGH-- 646
N +GS+ C+CP G +G C ++ LRP + G +
Sbjct: 3587 HNLQGSYRCLCPPGQTLLRDGKACTSLERNGQNVTTVSHRGPLLPWLRPWASIPGTSYHA 3646
Query: 647 ---------CVNTVGAFRCEYCDSGYRMTQRGRCEDIDECLNPSTCPDEQCVNSPGSYQC 697
+++VG +C G+ + Q G C D+DEC + C C N+ GSYQC
Sbjct: 3647 WVSLRPGPMALSSVGR---AWCPPGF-IRQNGVCTDLDECRVRNLC-QHACRNTEGSYQC 3701
Query: 698 VPCTEGFR----GWNGQCLDVDECLEPNV-CANGD-CSNLEGSYMC---SCHKGYTRTPD 748
+ C G+R G N C D++EC E ++ C G C N GSY C C Y + P
Sbjct: 3702 L-CPAGYRLLPSGKN--CQDINECEEESIECGPGQMCFNTRGSYQCVDTPCPATYRQGPS 3758
Query: 749 HKHC--RDIDECQQG 761
C R +C G
Sbjct: 3759 PGTCFRRCSQDCGTG 3773
Score = 71.2 bits (173), Expect = 6e-12
Identities = 69/237 (29%), Positives = 85/237 (35%), Gaps = 55/237 (23%)
Query: 946 CYQGFQAPQDGQGCVDVNECELLSGVCGEAFCENVEGSFLCVCADENQEYSPMTGQCRSR 1005
C +GF+ G CVD +EC C A C N G F C C
Sbjct: 3428 CPEGFELDSQGAFCVDRDECSGGPSPCSHA-CLNAPGRFSCTCP---------------- 3470
Query: 1006 TSTDLDVDVDQPKEEKKECYYNLNDASLCDNVLAPNVTKQECCCTSGAGWGDNCEIFPCP 1065
T L D D+ + EC + DA LC G C
Sbjct: 3471 TGFALAWD-DRNCRDVDECAW---DAHLCRE-------------------GQRC----VN 3503
Query: 1066 VLGTAEFTEMCPKGKGFVPAGESSSEAGGENYKDADECLLFGQEICKNGFCLNTRPGYEC 1125
+LG+ C G GF A G +D DECL + N C NT G+ C
Sbjct: 3504 LLGSYRCLPDC--GPGF-------RVADGAGCEDVDECLEGLDDCHYNQLCENTPGGHRC 3554
Query: 1126 YCKQGTYYDPVKLQCFDMDEC-QDPSSCIDGQCVNTEGSYNCFCTHPMVLDASEKRC 1181
C +G L C D++EC Q P +C QC N +GSY C C L K C
Sbjct: 3555 SCPRGYRMQGPSLPCLDVNECLQLPKACAY-QCHNLQGSYRCLCPPGQTLLRDGKAC 3610
Score = 68.2 bits (165), Expect = 5e-11
Identities = 90/334 (26%), Positives = 118/334 (35%), Gaps = 66/334 (19%)
Query: 1099 DADECLLFGQEICKNGFCLNTRPGYECYCKQGTYYDPVKLQCFDMDECQ-DPSSCIDGQ- 1156
D DEC G C + CLN + C C G C D+DEC D C +GQ
Sbjct: 3443 DRDECS-GGPSPCSHA-CLNAPGRFSCTCPTGFALAWDDRNCRDVDECAWDAHLCREGQR 3500
Query: 1157 CVNTEGSYNCFCT-HPMVLDASEKRCIRPAESNEQIEETDVYQDLCWEHLSDEYVCSRPL 1215
CVN GSY C P A C E E +++ Y LC E+ + CS P
Sbjct: 3501 CVNLLGSYRCLPDCGPGFRVADGAGCEDVDECLEGLDDCH-YNQLC-ENTPGGHRCSCPR 3558
Query: 1216 VGK-QTTYTEC-----CCLYGEAWGMQC--------ALCP-----LKDSDDYAQL----C 1252
+ Q C C +A QC LCP L+D L
Sbjct: 3559 GYRMQGPSLPCLDVNECLQLPKACAYQCHNLQGSYRCLCPPGQTLLRDGKACTSLERNGQ 3618
Query: 1253 NIPVTGRRQPY-----------------------GRDALVDFSEQYTPEADPYFIQDRFL 1289
N+ R P G AL + P P FI+ +
Sbjct: 3619 NVTTVSHRGPLLPWLRPWASIPGTSYHAWVSLRPGPMALSSVGRAWCP---PGFIRQNGV 3675
Query: 1290 NSFEELQAEECGILNGCENGRCVRVQEGYTCDCFDGYHLDTAKMTCVDVNECDELNNRMS 1349
+ +EC + N C++ C + Y C C GY L + C D+NEC+E +
Sbjct: 3676 CT----DLDECRVRNLCQHA-CRNTEGSYQCLCPAGYRLLPSGKNCQDINECEE--ESIE 3728
Query: 1350 LCKNAKCINTDGSYKCL---CLPGYVPSDKPNYC 1380
C NT GSY+C+ C Y P C
Sbjct: 3729 CGPGQMCFNTRGSYQCVDTPCPATYRQGPSPGTC 3762
Score = 55.1 bits (131), Expect = 5e-07
Identities = 30/88 (34%), Positives = 43/88 (48%), Gaps = 6/88 (6%)
Query: 547 TEINECTVNPDICGAGHCINLPVRYTCICYEGYRFSEQQRKCVDIDECTQVQHLCSQGR- 605
T+++EC V ++C C N Y C+C GYR + C DI+EC + C G+
Sbjct: 3677 TDLDECRVR-NLCQHA-CRNTEGSYQCLCPAGYRLLPSGKNCQDINECEEESIECGPGQM 3734
Query: 606 CENTEGSFLCI---CPAGFMASEEGTNC 630
C NT GS+ C+ CPA + C
Sbjct: 3735 CFNTRGSYQCVDTPCPATYRQGPSPGTC 3762
Score = 54.3 bits (129), Expect = 8e-07
Identities = 29/82 (35%), Positives = 38/82 (46%), Gaps = 5/82 (6%)
Query: 1303 LNGCE-NGRCVRVQEGYTCDCFDGYHLDTAKMTCVDVNECDELNNRMSLCKNAKCINTDG 1361
L+ C N C G+ C C GY + + C+DVNEC +L + +C N G
Sbjct: 3536 LDDCHYNQLCENTPGGHRCSCPRGYRMQGPSLPCLDVNECLQLPKACAY----QCHNLQG 3591
Query: 1362 SYKCLCLPGYVPSDKPNYCTPL 1383
SY+CLC PG CT L
Sbjct: 3592 SYRCLCPPGQTLLRDGKACTSL 3613
Score = 48.9 bits (115), Expect = 3e-05
Identities = 46/181 (25%), Positives = 73/181 (40%), Gaps = 23/181 (12%)
Query: 286 CLPGYKRVNNTFCQDINECQLQGVCPNGECLNTMGSYRCTCKIGFGPDPTFSSCVPDPPV 345
C PG+ R N C D++EC+++ +C + C NT GSY+C C G+ P+ +C D
Sbjct: 3665 CPPGFIRQNGV-CTDLDECRVRNLCQHA-CRNTEGSYQCLCPAGYRLLPSGKNC-QDINE 3721
Query: 346 ISEEKGPCYRLVSSGRQCMHPLSVHLTKQLCCCSVGKAWGPHCEKCPLPGTAAFKEICPG 405
EE C G+ C + + C + + + P PGT +
Sbjct: 3722 CEEESIEC----GPGQMCFNTRGSYQCVDTPCPATYR-------QGPSPGTCFRRCSQDC 3770
Query: 406 GMGYTVSGVHRRRPI------HHHVGKGPVFVK---PKNTQPVAKSTHPPPLPAKEEPVE 456
G G + +R P+ HH V + F + P N ++ P P P+
Sbjct: 3771 GTGGPSTLQYRLLPLPLGVRAHHDVARLTAFSEVGVPANRTELSMLEPDPRSPFALRPLR 3830
Query: 457 A 457
A
Sbjct: 3831 A 3831
Score = 42.7 bits (99), Expect = 0.002
Identities = 32/125 (25%), Positives = 57/125 (45%), Gaps = 9/125 (7%)
Query: 262 SWGFNKCQKCPKKPSYHG-YNQMMECLPGYKRVNNTFCQDINECQLQGVCP---NGECLN 317
+W + C++ + + G Y + +C PG++ + C+D++EC L+G+ N C N
Sbjct: 3489 AWDAHLCREGQRCVNLLGSYRCLPDCGPGFRVADGAGCEDVDEC-LEGLDDCHYNQLCEN 3547
Query: 318 TMGSYRCTCKIGFGPDPTFSSCVPDPPVISEEKG---PCYRLVSSGRQCMHPLSVHLTKQ 374
T G +RC+C G+ C+ + K C+ L S R C+ P L +
Sbjct: 3548 TPGGHRCSCPRGYRMQGPSLPCLDVNECLQLPKACAYQCHNLQGSYR-CLCPPGQTLLRD 3606
Query: 375 LCCCS 379
C+
Sbjct: 3607 GKACT 3611
Score = 42.7 bits (99), Expect = 0.002
Identities = 29/87 (33%), Positives = 36/87 (41%), Gaps = 5/87 (5%)
Query: 1307 ENGRCVRVQEGYTC--DCFDGYHLDTAKMTCVDVNECDELNNRMSLCKNAKCINTDGSYK 1364
E RCV + Y C DC G+ + C DV+EC L N C NT G ++
Sbjct: 3497 EGQRCVNLLGSYRCLPDCGPGFRVADGA-GCEDVDEC--LEGLDDCHYNQLCENTPGGHR 3553
Query: 1365 CLCLPGYVPSDKPNYCTPLNTALNLEK 1391
C C GY C +N L L K
Sbjct: 3554 CSCPRGYRMQGPSLPCLDVNECLQLPK 3580
Score = 37.0 bits (84), Expect = 0.13
Identities = 18/50 (36%), Positives = 27/50 (54%), Gaps = 4/50 (8%)
Query: 1322 CFDGYHLDTAKMTCVDVNECDELNNRMSLCKNAKCINTDGSYKCLCLPGY 1371
C +G+ LD+ CVD +EC + S C +A C+N G + C C G+
Sbjct: 3428 CPEGFELDSQGAFCVDRDEC---SGGPSPCSHA-CLNAPGRFSCTCPTGF 3473
>gi|239749684 PREDICTED: hemicentin 2 [Homo sapiens]
Length = 5065
Score = 203 bits (516), Expect = 1e-51
Identities = 129/329 (39%), Positives = 161/329 (48%), Gaps = 45/329 (13%)
Query: 575 CYEGYRFSEQQRKCVDIDECTQVQHLCSQGRCENTEGSFLCICPAGFMASEEGTNCIDVD 634
C EG+ Q CVD DEC+ CS C N G F C CP GF + + NC DVD
Sbjct: 4619 CPEGFELDSQGAFCVDRDECSGGPSPCSHA-CLNAPGRFSCTCPTGFALAWDDRNCRDVD 4677
Query: 635 ECL-RPDVCGEG-HCVNTVGAFRC-EYCDSGYRMTQRGRCEDIDECLNP-STCPDEQ-CV 689
EC +C EG CVN +G++RC C G+R+ CED+DECL C Q C
Sbjct: 4678 ECAWDAHLCREGQRCVNLLGSYRCLPDCGPGFRVADGAGCEDVDECLEGLDDCHYNQLCE 4737
Query: 690 NSPGSYQCVPCTEGFR--GWNGQCLDVDECLE-PNVCANGDCSNLEGSYMCSCHKGYTRT 746
N+PG ++C C G+R G + CLDV+ECL+ P CA C NL+GSY C C G T
Sbjct: 4738 NTPGGHRC-SCPRGYRMQGPSLPCLDVNECLQLPKACAY-QCHNLQGSYRCLCPPGQTLL 4795
Query: 747 PDHKHCRDIDECQQGNLCVN----------------GQCKNTEGSF-----------RCT 779
D K C ++ Q V+ G + S R
Sbjct: 4796 RDGKACTSLERNGQNVTTVSHRGPLLPWLRPWASIPGTSYHAWVSLRPGPMALSSVGRAW 4855
Query: 780 CGQGYQLSAAKDQCEDIDECQHRHLCAHGQCRNTEGSFQCVCDQGYRASGLGDHCEDINE 839
C G+ C D+DEC+ R+LC H CRNTEGS+QC+C GYR G +C+DINE
Sbjct: 4856 CPPGF--IRQNGVCTDLDECRVRNLCQHA-CRNTEGSYQCLCPAGYRLLPSGKNCQDINE 4912
Query: 840 CLEDKSVCQRGD-CINTAGSYDCT---CP 864
C E+ C G C NT GSY C CP
Sbjct: 4913 CEEESIECGPGQMCFNTRGSYQCVDTPCP 4941
Score = 177 bits (448), Expect = 8e-44
Identities = 125/353 (35%), Positives = 162/353 (45%), Gaps = 50/353 (14%)
Query: 698 VPCTEGFR--GWNGQCLDVDECLE-PNVCANGDCSNLEGSYMCSCHKGYTRTPDHKHCRD 754
V C EGF C+D DEC P+ C++ C N G + C+C G+ D ++CRD
Sbjct: 4617 VGCPEGFELDSQGAFCVDRDECSGGPSPCSHA-CLNAPGRFSCTCPTGFALAWDDRNCRD 4675
Query: 755 IDECQ-QGNLCVNGQ-CKNTEGSFRCT--CGQGYQLSAAKDQCEDIDEC-QHRHLCAHGQ 809
+DEC +LC GQ C N GS+RC CG G++++ CED+DEC + C + Q
Sbjct: 4676 VDECAWDAHLCREGQRCVNLLGSYRCLPDCGPGFRVADGAG-CEDVDECLEGLDDCHYNQ 4734
Query: 810 -CRNTEGSFQCVCDQGYRASGLGDHCEDINECLEDKSVCQRGDCINTAGSYDCTCPDGFQ 868
C NT G +C C +GYR G C D+NECL+ C C N GSY C CP G
Sbjct: 4735 LCENTPGGHRCSCPRGYRMQGPSLPCLDVNECLQLPKACAY-QCHNLQGSYRCLCPPGQT 4793
Query: 869 L-DDNKTC-------QDINECEHPG---------------------LCGPQGECLNTEGS 899
L D K C Q++ H G P L++ G
Sbjct: 4794 LLRDGKACTSLERNGQNVTTVSHRGPLLPWLRPWASIPGTSYHAWVSLRPGPMALSSVG- 4852
Query: 900 FHCVCQQGFSISADGRTCEDIDECVNNTVCDSHGFCDNTAGSFRCLCYQGFQAPQDGQGC 959
C GF I +G C D+DEC +C C NT GS++CLC G++ G+ C
Sbjct: 4853 -RAWCPPGF-IRQNG-VCTDLDECRVRNLCQHA--CRNTEGSYQCLCPAGYRLLPSGKNC 4907
Query: 960 VDVNECELLSGVCGEA-FCENVEGSFLCVCADENQEY--SPMTGQCRSRTSTD 1009
D+NECE S CG C N GS+ CV Y P G C R S D
Sbjct: 4908 QDINECEEESIECGPGQMCFNTRGSYQCVDTPCPATYRQGPSPGTCFRRCSQD 4960
Score = 172 bits (436), Expect = 2e-42
Identities = 111/325 (34%), Positives = 158/325 (48%), Gaps = 45/325 (13%)
Query: 659 CDSGYRMTQRGR-CEDIDECLN-PSTCPDEQCVNSPGSYQCVPCTEGFR-GWNGQ-CLDV 714
C G+ + +G C D DEC PS C C+N+PG + C C GF W+ + C DV
Sbjct: 4619 CPEGFELDSQGAFCVDRDECSGGPSPC-SHACLNAPGRFSCT-CPTGFALAWDDRNCRDV 4676
Query: 715 DECL-EPNVCANGD-CSNLEGSYMC--SCHKGYTRTPDHKHCRDIDECQQG--NLCVNGQ 768
DEC + ++C G C NL GSY C C G+ R D C D+DEC +G + N
Sbjct: 4677 DECAWDAHLCREGQRCVNLLGSYRCLPDCGPGF-RVADGAGCEDVDECLEGLDDCHYNQL 4735
Query: 769 CKNTEGSFRCTCGQGYQLSAAKDQCEDIDEC-QHRHLCAHGQCRNTEGSFQCVCDQGYRA 827
C+NT G RC+C +GY++ C D++EC Q CA+ QC N +GS++C+C G
Sbjct: 4736 CENTPGGHRCSCPRGYRMQGPSLPCLDVNECLQLPKACAY-QCHNLQGSYRCLCPPGQTL 4794
Query: 828 SGLGDHCEDINECLED-KSVCQRGDCIN--------TAGSYDCT---------------- 862
G C + ++ +V RG + SY
Sbjct: 4795 LRDGKACTSLERNGQNVTTVSHRGPLLPWLRPWASIPGTSYHAWVSLRPGPMALSSVGRA 4854
Query: 863 -CPDGFQLDDNKTCQDINECEHPGLCGPQGECLNTEGSFHCVCQQGFSISADGRTCEDID 921
CP GF + N C D++EC LC Q C NTEGS+ C+C G+ + G+ C+DI+
Sbjct: 4855 WCPPGF-IRQNGVCTDLDECRVRNLC--QHACRNTEGSYQCLCPAGYRLLPSGKNCQDIN 4911
Query: 922 ECVNNTV-CDSHGFCDNTAGSFRCL 945
EC ++ C C NT GS++C+
Sbjct: 4912 ECEEESIECGPGQMCFNTRGSYQCV 4936
Score = 172 bits (435), Expect = 3e-42
Identities = 117/325 (36%), Positives = 152/325 (46%), Gaps = 45/325 (13%)
Query: 617 CPAGFMASEEGTNCIDVDECLR-PDVCGEGHCVNTVGAFRCEYCDSGYRMTQRGR-CEDI 674
CP GF +G C+D DEC P C C+N G F C C +G+ + R C D+
Sbjct: 4619 CPEGFELDSQGAFCVDRDECSGGPSPCSHA-CLNAPGRFSCT-CPTGFALAWDDRNCRDV 4676
Query: 675 DECL-NPSTCPDEQ-CVNSPGSYQCVP-CTEGFRGWNGQ-CLDVDECLE--PNVCANGDC 728
DEC + C + Q CVN GSY+C+P C GFR +G C DVDECLE + N C
Sbjct: 4677 DECAWDAHLCREGQRCVNLLGSYRCLPDCGPGFRVADGAGCEDVDECLEGLDDCHYNQLC 4736
Query: 729 SNLEGSYMCSCHKGYTRTPDHKHCRDIDECQQGNLCVNGQCKNTEGSFRCTCGQGYQLSA 788
N G + CSC +GY C D++EC Q QC N +GS+RC C G L
Sbjct: 4737 ENTPGGHRCSCPRGYRMQGPSLPCLDVNECLQLPKACAYQCHNLQGSYRCLCPPGQTLLR 4796
Query: 789 AKDQC-------EDIDECQHRH--------------LCAHGQCRNTEGSF------QCVC 821
C +++ HR H G + C
Sbjct: 4797 DGKACTSLERNGQNVTTVSHRGPLLPWLRPWASIPGTSYHAWVSLRPGPMALSSVGRAWC 4856
Query: 822 DQGY-RASGLGDHCEDINECLEDKSVCQRGDCINTAGSYDCTCPDGFQ-LDDNKTCQDIN 879
G+ R +G+ C D++EC +++CQ C NT GSY C CP G++ L K CQDIN
Sbjct: 4857 PPGFIRQNGV---CTDLDEC-RVRNLCQHA-CRNTEGSYQCLCPAGYRLLPSGKNCQDIN 4911
Query: 880 ECEHPGL-CGPQGECLNTEGSFHCV 903
ECE + CGP C NT GS+ CV
Sbjct: 4912 ECEEESIECGPGQMCFNTRGSYQCV 4936
Score = 161 bits (408), Expect = 4e-39
Identities = 119/336 (35%), Positives = 157/336 (46%), Gaps = 53/336 (15%)
Query: 550 NECTVNPDICGAGHCINLPVRYTCICYEGYRFSEQQRKCVDIDECTQVQHLCSQG-RCEN 608
+EC+ P C C+N P R++C C G+ + R C D+DEC HLC +G RC N
Sbjct: 4636 DECSGGPSPCSHA-CLNAPGRFSCTCPTGFALAWDDRNCRDVDECAWDAHLCREGQRCVN 4694
Query: 609 TEGSFLCI--CPAGFMASEEGTNCIDVDECLRP-DVCGEGH-CVNTVGAFRCEYCDSGYR 664
GS+ C+ C GF + +G C DVDECL D C C NT G RC C GYR
Sbjct: 4695 LLGSYRCLPDCGPGFRVA-DGAGCEDVDECLEGLDDCHYNQLCENTPGGHRCS-CPRGYR 4752
Query: 665 MTQRG-RCEDIDECLN-PSTCPDEQCVNSPGSYQCV------------PCTEGFRGWNGQ 710
M C D++ECL P C QC N GSY+C+ CT R NGQ
Sbjct: 4753 MQGPSLPCLDVNECLQLPKACA-YQCHNLQGSYRCLCPPGQTLLRDGKACTSLER--NGQ 4809
Query: 711 CLDVDECLEPNVCANGDCSNLEG-SY-----------------MCSCHKGYTRTPDHKHC 752
+ P + +++ G SY C G+ R + C
Sbjct: 4810 NVTTVSHRGPLLPWLRPWASIPGTSYHAWVSLRPGPMALSSVGRAWCPPGFIR--QNGVC 4867
Query: 753 RDIDECQQGNLCVNGQCKNTEGSFRCTCGQGYQLSAAKDQCEDIDECQHRHL-CAHGQ-C 810
D+DEC+ NLC + C+NTEGS++C C GY+L + C+DI+EC+ + C GQ C
Sbjct: 4868 TDLDECRVRNLCQHA-CRNTEGSYQCLCPAGYRLLPSGKNCQDINECEEESIECGPGQMC 4926
Query: 811 RNTEGSFQCV---CDQGYRASGLGDHCEDINECLED 843
NT GS+QCV C YR C C +D
Sbjct: 4927 FNTRGSYQCVDTPCPATYRQGPSPGTC--FRRCSQD 4960
Score = 144 bits (363), Expect = 6e-34
Identities = 100/319 (31%), Positives = 143/319 (44%), Gaps = 50/319 (15%)
Query: 739 CHKGYTRTPDHKHCRDIDECQQGNLCVNGQCKNTEGSFRCTCGQGYQLSAAKDQCEDIDE 798
C +G+ C D DEC G + C N G F CTC G+ L+ C D+DE
Sbjct: 4619 CPEGFELDSQGAFCVDRDECSGGPSPCSHACLNAPGRFSCTCPTGFALAWDDRNCRDVDE 4678
Query: 799 CQ-HRHLCAHGQ-CRNTEGSFQCV--CDQGYRASGLGDHCEDINECLEDKSVCQRGD-CI 853
C HLC GQ C N GS++C+ C G+R + G CED++ECLE C C
Sbjct: 4679 CAWDAHLCREGQRCVNLLGSYRCLPDCGPGFRVAD-GAGCEDVDECLEGLDDCHYNQLCE 4737
Query: 854 NTAGSYDCTCPDGFQLDD-NKTCQDINEC-EHPGLCGPQGECLNTEGSFHCVCQQGFSIS 911
NT G + C+CP G+++ + C D+NEC + P C Q C N +GS+ C+C G ++
Sbjct: 4738 NTPGGHRCSCPRGYRMQGPSLPCLDVNECLQLPKACAYQ--CHNLQGSYRCLCPPGQTLL 4795
Query: 912 ADGRTCEDIDECVNNTVCDSH---------GFCDNTAGSF-----------------RCL 945
DG+ C ++ N SH + S+ R
Sbjct: 4796 RDGKACTSLERNGQNVTTVSHRGPLLPWLRPWASIPGTSYHAWVSLRPGPMALSSVGRAW 4855
Query: 946 CYQGFQAPQDGQGCVDVNECELLSGVCGEAFCENVEGSFLCVCADENQEYSPMTGQCRSR 1005
C GF Q+G C D++EC + +C A C N EGS+ C+C P C+
Sbjct: 4856 CPPGF-IRQNGV-CTDLDECR-VRNLCQHA-CRNTEGSYQCLC-PAGYRLLPSGKNCQ-- 4908
Query: 1006 TSTDLDVDVDQPKEEKKEC 1024
D+++ +EE EC
Sbjct: 4909 -------DINECEEESIEC 4920
Score = 125 bits (313), Expect = 4e-28
Identities = 104/333 (31%), Positives = 141/333 (42%), Gaps = 39/333 (11%)
Query: 863 CPDGFQLDDNKT-CQDINECEH-PGLCGPQGECLNTEGSFHCVCQQGFSISADGRTCEDI 920
CP+GF+LD C D +EC P C CLN G F C C GF+++ D R C D+
Sbjct: 4619 CPEGFELDSQGAFCVDRDECSGGPSPCSHA--CLNAPGRFSCTCPTGFALAWDDRNCRDV 4676
Query: 921 DECVNNT-VCDSHGFCDNTAGSFRCL--CYQGFQAPQDGQGCVDVNEC-ELLSGVCGEAF 976
DEC + +C C N GS+RCL C GF+ DG GC DV+EC E L
Sbjct: 4677 DECAWDAHLCREGQRCVNLLGSYRCLPDCGPGFRVA-DGAGCEDVDECLEGLDDCHYNQL 4735
Query: 977 CENVEGSFLCVCADENQEYSPMTGQCRSRTSTDLDVDVDQPKEEKKECYYNLNDASLCDN 1036
CEN G C C + P S D++ + PK +C+ NL + C
Sbjct: 4736 CENTPGGHRCSCPRGYRMQGP------SLPCLDVNECLQLPKACAYQCH-NLQGSYRCLC 4788
Query: 1037 VLAPNVTKQECCCTSGAGWGDNCE-------IFP-----CPVLGTA--EFTEMCPKGKGF 1082
+ + CTS G N + P + GT+ + + P
Sbjct: 4789 PPGQTLLRDGKACTSLERNGQNVTTVSHRGPLLPWLRPWASIPGTSYHAWVSLRPGPMAL 4848
Query: 1083 VPAGESSSEAGGENYK----DADECLLFGQEICKNGFCLNTRPGYECYCKQGTYYDPVKL 1138
G + G D DEC + + +C++ C NT Y+C C G P
Sbjct: 4849 SSVGRAWCPPGFIRQNGVCTDLDECRV--RNLCQHA-CRNTEGSYQCLCPAGYRLLPSGK 4905
Query: 1139 QCFDMDECQDPS-SCIDGQ-CVNTEGSYNCFCT 1169
C D++EC++ S C GQ C NT GSY C T
Sbjct: 4906 NCQDINECEEESIECGPGQMCFNTRGSYQCVDT 4938
Score = 100 bits (248), Expect = 1e-20
Identities = 76/255 (29%), Positives = 111/255 (43%), Gaps = 50/255 (19%)
Query: 548 EINECTVNPDICGAGH-CINLPVRYTCICYEGYRFSEQQRKCVDIDECTQVQHLCSQGRC 606
+++EC D C C N P + C C GYR C+D++EC Q+ C+ +C
Sbjct: 4719 DVDECLEGLDDCHYNQLCENTPGGHRCSCPRGYRMQGPSLPCLDVNECLQLPKACAY-QC 4777
Query: 607 ENTEGSFLCICPAGFMASEEGTNCIDVDE----------------CLRP--DVCGEGH-- 646
N +GS+ C+CP G +G C ++ LRP + G +
Sbjct: 4778 HNLQGSYRCLCPPGQTLLRDGKACTSLERNGQNVTTVSHRGPLLPWLRPWASIPGTSYHA 4837
Query: 647 ---------CVNTVGAFRCEYCDSGYRMTQRGRCEDIDECLNPSTCPDEQCVNSPGSYQC 697
+++VG +C G+ + Q G C D+DEC + C C N+ GSYQC
Sbjct: 4838 WVSLRPGPMALSSVGR---AWCPPGF-IRQNGVCTDLDECRVRNLC-QHACRNTEGSYQC 4892
Query: 698 VPCTEGFR----GWNGQCLDVDECLEPNV-CANGD-CSNLEGSYMC---SCHKGYTRTPD 748
+ C G+R G N C D++EC E ++ C G C N GSY C C Y + P
Sbjct: 4893 L-CPAGYRLLPSGKN--CQDINECEEESIECGPGQMCFNTRGSYQCVDTPCPATYRQGPS 4949
Query: 749 HKHC--RDIDECQQG 761
C R +C G
Sbjct: 4950 PGTCFRRCSQDCGTG 4964
Score = 71.2 bits (173), Expect = 6e-12
Identities = 69/237 (29%), Positives = 85/237 (35%), Gaps = 55/237 (23%)
Query: 946 CYQGFQAPQDGQGCVDVNECELLSGVCGEAFCENVEGSFLCVCADENQEYSPMTGQCRSR 1005
C +GF+ G CVD +EC C A C N G F C C
Sbjct: 4619 CPEGFELDSQGAFCVDRDECSGGPSPCSHA-CLNAPGRFSCTCP---------------- 4661
Query: 1006 TSTDLDVDVDQPKEEKKECYYNLNDASLCDNVLAPNVTKQECCCTSGAGWGDNCEIFPCP 1065
T L D D+ + EC + DA LC G C
Sbjct: 4662 TGFALAWD-DRNCRDVDECAW---DAHLCRE-------------------GQRC----VN 4694
Query: 1066 VLGTAEFTEMCPKGKGFVPAGESSSEAGGENYKDADECLLFGQEICKNGFCLNTRPGYEC 1125
+LG+ C G GF A G +D DECL + N C NT G+ C
Sbjct: 4695 LLGSYRCLPDC--GPGF-------RVADGAGCEDVDECLEGLDDCHYNQLCENTPGGHRC 4745
Query: 1126 YCKQGTYYDPVKLQCFDMDEC-QDPSSCIDGQCVNTEGSYNCFCTHPMVLDASEKRC 1181
C +G L C D++EC Q P +C QC N +GSY C C L K C
Sbjct: 4746 SCPRGYRMQGPSLPCLDVNECLQLPKACAY-QCHNLQGSYRCLCPPGQTLLRDGKAC 4801
Score = 68.2 bits (165), Expect = 5e-11
Identities = 90/334 (26%), Positives = 118/334 (35%), Gaps = 66/334 (19%)
Query: 1099 DADECLLFGQEICKNGFCLNTRPGYECYCKQGTYYDPVKLQCFDMDECQ-DPSSCIDGQ- 1156
D DEC G C + CLN + C C G C D+DEC D C +GQ
Sbjct: 4634 DRDECS-GGPSPCSHA-CLNAPGRFSCTCPTGFALAWDDRNCRDVDECAWDAHLCREGQR 4691
Query: 1157 CVNTEGSYNCFCT-HPMVLDASEKRCIRPAESNEQIEETDVYQDLCWEHLSDEYVCSRPL 1215
CVN GSY C P A C E E +++ Y LC E+ + CS P
Sbjct: 4692 CVNLLGSYRCLPDCGPGFRVADGAGCEDVDECLEGLDDCH-YNQLC-ENTPGGHRCSCPR 4749
Query: 1216 VGK-QTTYTEC-----CCLYGEAWGMQC--------ALCP-----LKDSDDYAQL----C 1252
+ Q C C +A QC LCP L+D L
Sbjct: 4750 GYRMQGPSLPCLDVNECLQLPKACAYQCHNLQGSYRCLCPPGQTLLRDGKACTSLERNGQ 4809
Query: 1253 NIPVTGRRQPY-----------------------GRDALVDFSEQYTPEADPYFIQDRFL 1289
N+ R P G AL + P P FI+ +
Sbjct: 4810 NVTTVSHRGPLLPWLRPWASIPGTSYHAWVSLRPGPMALSSVGRAWCP---PGFIRQNGV 4866
Query: 1290 NSFEELQAEECGILNGCENGRCVRVQEGYTCDCFDGYHLDTAKMTCVDVNECDELNNRMS 1349
+ +EC + N C++ C + Y C C GY L + C D+NEC+E +
Sbjct: 4867 CT----DLDECRVRNLCQHA-CRNTEGSYQCLCPAGYRLLPSGKNCQDINECEE--ESIE 4919
Query: 1350 LCKNAKCINTDGSYKCL---CLPGYVPSDKPNYC 1380
C NT GSY+C+ C Y P C
Sbjct: 4920 CGPGQMCFNTRGSYQCVDTPCPATYRQGPSPGTC 4953
Score = 55.1 bits (131), Expect = 5e-07
Identities = 30/88 (34%), Positives = 43/88 (48%), Gaps = 6/88 (6%)
Query: 547 TEINECTVNPDICGAGHCINLPVRYTCICYEGYRFSEQQRKCVDIDECTQVQHLCSQGR- 605
T+++EC V ++C C N Y C+C GYR + C DI+EC + C G+
Sbjct: 4868 TDLDECRVR-NLCQHA-CRNTEGSYQCLCPAGYRLLPSGKNCQDINECEEESIECGPGQM 4925
Query: 606 CENTEGSFLCI---CPAGFMASEEGTNC 630
C NT GS+ C+ CPA + C
Sbjct: 4926 CFNTRGSYQCVDTPCPATYRQGPSPGTC 4953
Score = 54.3 bits (129), Expect = 8e-07
Identities = 29/82 (35%), Positives = 38/82 (46%), Gaps = 5/82 (6%)
Query: 1303 LNGCE-NGRCVRVQEGYTCDCFDGYHLDTAKMTCVDVNECDELNNRMSLCKNAKCINTDG 1361
L+ C N C G+ C C GY + + C+DVNEC +L + +C N G
Sbjct: 4727 LDDCHYNQLCENTPGGHRCSCPRGYRMQGPSLPCLDVNECLQLPKACAY----QCHNLQG 4782
Query: 1362 SYKCLCLPGYVPSDKPNYCTPL 1383
SY+CLC PG CT L
Sbjct: 4783 SYRCLCPPGQTLLRDGKACTSL 4804
Score = 48.9 bits (115), Expect = 3e-05
Identities = 46/181 (25%), Positives = 73/181 (40%), Gaps = 23/181 (12%)
Query: 286 CLPGYKRVNNTFCQDINECQLQGVCPNGECLNTMGSYRCTCKIGFGPDPTFSSCVPDPPV 345
C PG+ R N C D++EC+++ +C + C NT GSY+C C G+ P+ +C D
Sbjct: 4856 CPPGFIRQNGV-CTDLDECRVRNLCQHA-CRNTEGSYQCLCPAGYRLLPSGKNC-QDINE 4912
Query: 346 ISEEKGPCYRLVSSGRQCMHPLSVHLTKQLCCCSVGKAWGPHCEKCPLPGTAAFKEICPG 405
EE C G+ C + + C + + + P PGT +
Sbjct: 4913 CEEESIEC----GPGQMCFNTRGSYQCVDTPCPATYR-------QGPSPGTCFRRCSQDC 4961
Query: 406 GMGYTVSGVHRRRPI------HHHVGKGPVFVK---PKNTQPVAKSTHPPPLPAKEEPVE 456
G G + +R P+ HH V + F + P N ++ P P P+
Sbjct: 4962 GTGGPSTLQYRLLPLPLGVRAHHDVARLTAFSEVGVPANRTELSMLEPDPRSPFALRPLR 5021
Query: 457 A 457
A
Sbjct: 5022 A 5022
Score = 42.7 bits (99), Expect = 0.002
Identities = 32/125 (25%), Positives = 57/125 (45%), Gaps = 9/125 (7%)
Query: 262 SWGFNKCQKCPKKPSYHG-YNQMMECLPGYKRVNNTFCQDINECQLQGVCP---NGECLN 317
+W + C++ + + G Y + +C PG++ + C+D++EC L+G+ N C N
Sbjct: 4680 AWDAHLCREGQRCVNLLGSYRCLPDCGPGFRVADGAGCEDVDEC-LEGLDDCHYNQLCEN 4738
Query: 318 TMGSYRCTCKIGFGPDPTFSSCVPDPPVISEEKG---PCYRLVSSGRQCMHPLSVHLTKQ 374
T G +RC+C G+ C+ + K C+ L S R C+ P L +
Sbjct: 4739 TPGGHRCSCPRGYRMQGPSLPCLDVNECLQLPKACAYQCHNLQGSYR-CLCPPGQTLLRD 4797
Query: 375 LCCCS 379
C+
Sbjct: 4798 GKACT 4802
Score = 42.7 bits (99), Expect = 0.002
Identities = 29/87 (33%), Positives = 36/87 (41%), Gaps = 5/87 (5%)
Query: 1307 ENGRCVRVQEGYTC--DCFDGYHLDTAKMTCVDVNECDELNNRMSLCKNAKCINTDGSYK 1364
E RCV + Y C DC G+ + C DV+EC L N C NT G ++
Sbjct: 4688 EGQRCVNLLGSYRCLPDCGPGFRVADGA-GCEDVDEC--LEGLDDCHYNQLCENTPGGHR 4744
Query: 1365 CLCLPGYVPSDKPNYCTPLNTALNLEK 1391
C C GY C +N L L K
Sbjct: 4745 CSCPRGYRMQGPSLPCLDVNECLQLPK 4771
Score = 37.0 bits (84), Expect = 0.13
Identities = 18/50 (36%), Positives = 27/50 (54%), Gaps = 4/50 (8%)
Query: 1322 CFDGYHLDTAKMTCVDVNECDELNNRMSLCKNAKCINTDGSYKCLCLPGY 1371
C +G+ LD+ CVD +EC + S C +A C+N G + C C G+
Sbjct: 4619 CPEGFELDSQGAFCVDRDEC---SGGPSPCSHA-CLNAPGRFSCTCPTGF 4664
>gi|169177000 PREDICTED: hemicentin 2 [Homo sapiens]
Length = 3783
Score = 203 bits (516), Expect = 1e-51
Identities = 129/329 (39%), Positives = 161/329 (48%), Gaps = 45/329 (13%)
Query: 575 CYEGYRFSEQQRKCVDIDECTQVQHLCSQGRCENTEGSFLCICPAGFMASEEGTNCIDVD 634
C EG+ Q CVD DEC+ CS C N G F C CP GF + + NC DVD
Sbjct: 3337 CPEGFELDSQGAFCVDRDECSGGPSPCSHA-CLNAPGRFSCTCPTGFALAWDDRNCRDVD 3395
Query: 635 ECL-RPDVCGEG-HCVNTVGAFRC-EYCDSGYRMTQRGRCEDIDECLNP-STCPDEQ-CV 689
EC +C EG CVN +G++RC C G+R+ CED+DECL C Q C
Sbjct: 3396 ECAWDAHLCREGQRCVNLLGSYRCLPDCGPGFRVADGAGCEDVDECLEGLDDCHYNQLCE 3455
Query: 690 NSPGSYQCVPCTEGFR--GWNGQCLDVDECLE-PNVCANGDCSNLEGSYMCSCHKGYTRT 746
N+PG ++C C G+R G + CLDV+ECL+ P CA C NL+GSY C C G T
Sbjct: 3456 NTPGGHRC-SCPRGYRMQGPSLPCLDVNECLQLPKACAY-QCHNLQGSYRCLCPPGQTLL 3513
Query: 747 PDHKHCRDIDECQQGNLCVN----------------GQCKNTEGSF-----------RCT 779
D K C ++ Q V+ G + S R
Sbjct: 3514 RDGKACTSLERNGQNVTTVSHRGPLLPWLRPWASIPGTSYHAWVSLRPGPMALSSVGRAW 3573
Query: 780 CGQGYQLSAAKDQCEDIDECQHRHLCAHGQCRNTEGSFQCVCDQGYRASGLGDHCEDINE 839
C G+ C D+DEC+ R+LC H CRNTEGS+QC+C GYR G +C+DINE
Sbjct: 3574 CPPGF--IRQNGVCTDLDECRVRNLCQHA-CRNTEGSYQCLCPAGYRLLPSGKNCQDINE 3630
Query: 840 CLEDKSVCQRGD-CINTAGSYDCT---CP 864
C E+ C G C NT GSY C CP
Sbjct: 3631 CEEESIECGPGQMCFNTRGSYQCVDTPCP 3659
Score = 177 bits (448), Expect = 8e-44
Identities = 125/353 (35%), Positives = 162/353 (45%), Gaps = 50/353 (14%)
Query: 698 VPCTEGFR--GWNGQCLDVDECLE-PNVCANGDCSNLEGSYMCSCHKGYTRTPDHKHCRD 754
V C EGF C+D DEC P+ C++ C N G + C+C G+ D ++CRD
Sbjct: 3335 VGCPEGFELDSQGAFCVDRDECSGGPSPCSHA-CLNAPGRFSCTCPTGFALAWDDRNCRD 3393
Query: 755 IDECQ-QGNLCVNGQ-CKNTEGSFRCT--CGQGYQLSAAKDQCEDIDEC-QHRHLCAHGQ 809
+DEC +LC GQ C N GS+RC CG G++++ CED+DEC + C + Q
Sbjct: 3394 VDECAWDAHLCREGQRCVNLLGSYRCLPDCGPGFRVADGAG-CEDVDECLEGLDDCHYNQ 3452
Query: 810 -CRNTEGSFQCVCDQGYRASGLGDHCEDINECLEDKSVCQRGDCINTAGSYDCTCPDGFQ 868
C NT G +C C +GYR G C D+NECL+ C C N GSY C CP G
Sbjct: 3453 LCENTPGGHRCSCPRGYRMQGPSLPCLDVNECLQLPKACAY-QCHNLQGSYRCLCPPGQT 3511
Query: 869 L-DDNKTC-------QDINECEHPG---------------------LCGPQGECLNTEGS 899
L D K C Q++ H G P L++ G
Sbjct: 3512 LLRDGKACTSLERNGQNVTTVSHRGPLLPWLRPWASIPGTSYHAWVSLRPGPMALSSVG- 3570
Query: 900 FHCVCQQGFSISADGRTCEDIDECVNNTVCDSHGFCDNTAGSFRCLCYQGFQAPQDGQGC 959
C GF I +G C D+DEC +C C NT GS++CLC G++ G+ C
Sbjct: 3571 -RAWCPPGF-IRQNG-VCTDLDECRVRNLCQHA--CRNTEGSYQCLCPAGYRLLPSGKNC 3625
Query: 960 VDVNECELLSGVCGEA-FCENVEGSFLCVCADENQEY--SPMTGQCRSRTSTD 1009
D+NECE S CG C N GS+ CV Y P G C R S D
Sbjct: 3626 QDINECEEESIECGPGQMCFNTRGSYQCVDTPCPATYRQGPSPGTCFRRCSQD 3678
Score = 172 bits (436), Expect = 2e-42
Identities = 111/325 (34%), Positives = 158/325 (48%), Gaps = 45/325 (13%)
Query: 659 CDSGYRMTQRGR-CEDIDECLN-PSTCPDEQCVNSPGSYQCVPCTEGFR-GWNGQ-CLDV 714
C G+ + +G C D DEC PS C C+N+PG + C C GF W+ + C DV
Sbjct: 3337 CPEGFELDSQGAFCVDRDECSGGPSPC-SHACLNAPGRFSCT-CPTGFALAWDDRNCRDV 3394
Query: 715 DECL-EPNVCANGD-CSNLEGSYMC--SCHKGYTRTPDHKHCRDIDECQQG--NLCVNGQ 768
DEC + ++C G C NL GSY C C G+ R D C D+DEC +G + N
Sbjct: 3395 DECAWDAHLCREGQRCVNLLGSYRCLPDCGPGF-RVADGAGCEDVDECLEGLDDCHYNQL 3453
Query: 769 CKNTEGSFRCTCGQGYQLSAAKDQCEDIDEC-QHRHLCAHGQCRNTEGSFQCVCDQGYRA 827
C+NT G RC+C +GY++ C D++EC Q CA+ QC N +GS++C+C G
Sbjct: 3454 CENTPGGHRCSCPRGYRMQGPSLPCLDVNECLQLPKACAY-QCHNLQGSYRCLCPPGQTL 3512
Query: 828 SGLGDHCEDINECLED-KSVCQRGDCIN--------TAGSYDCT---------------- 862
G C + ++ +V RG + SY
Sbjct: 3513 LRDGKACTSLERNGQNVTTVSHRGPLLPWLRPWASIPGTSYHAWVSLRPGPMALSSVGRA 3572
Query: 863 -CPDGFQLDDNKTCQDINECEHPGLCGPQGECLNTEGSFHCVCQQGFSISADGRTCEDID 921
CP GF + N C D++EC LC Q C NTEGS+ C+C G+ + G+ C+DI+
Sbjct: 3573 WCPPGF-IRQNGVCTDLDECRVRNLC--QHACRNTEGSYQCLCPAGYRLLPSGKNCQDIN 3629
Query: 922 ECVNNTV-CDSHGFCDNTAGSFRCL 945
EC ++ C C NT GS++C+
Sbjct: 3630 ECEEESIECGPGQMCFNTRGSYQCV 3654
Score = 172 bits (435), Expect = 3e-42
Identities = 117/325 (36%), Positives = 152/325 (46%), Gaps = 45/325 (13%)
Query: 617 CPAGFMASEEGTNCIDVDECLR-PDVCGEGHCVNTVGAFRCEYCDSGYRMTQRGR-CEDI 674
CP GF +G C+D DEC P C C+N G F C C +G+ + R C D+
Sbjct: 3337 CPEGFELDSQGAFCVDRDECSGGPSPCSHA-CLNAPGRFSCT-CPTGFALAWDDRNCRDV 3394
Query: 675 DECL-NPSTCPDEQ-CVNSPGSYQCVP-CTEGFRGWNGQ-CLDVDECLE--PNVCANGDC 728
DEC + C + Q CVN GSY+C+P C GFR +G C DVDECLE + N C
Sbjct: 3395 DECAWDAHLCREGQRCVNLLGSYRCLPDCGPGFRVADGAGCEDVDECLEGLDDCHYNQLC 3454
Query: 729 SNLEGSYMCSCHKGYTRTPDHKHCRDIDECQQGNLCVNGQCKNTEGSFRCTCGQGYQLSA 788
N G + CSC +GY C D++EC Q QC N +GS+RC C G L
Sbjct: 3455 ENTPGGHRCSCPRGYRMQGPSLPCLDVNECLQLPKACAYQCHNLQGSYRCLCPPGQTLLR 3514
Query: 789 AKDQC-------EDIDECQHRH--------------LCAHGQCRNTEGSF------QCVC 821
C +++ HR H G + C
Sbjct: 3515 DGKACTSLERNGQNVTTVSHRGPLLPWLRPWASIPGTSYHAWVSLRPGPMALSSVGRAWC 3574
Query: 822 DQGY-RASGLGDHCEDINECLEDKSVCQRGDCINTAGSYDCTCPDGFQ-LDDNKTCQDIN 879
G+ R +G+ C D++EC +++CQ C NT GSY C CP G++ L K CQDIN
Sbjct: 3575 PPGFIRQNGV---CTDLDEC-RVRNLCQHA-CRNTEGSYQCLCPAGYRLLPSGKNCQDIN 3629
Query: 880 ECEHPGL-CGPQGECLNTEGSFHCV 903
ECE + CGP C NT GS+ CV
Sbjct: 3630 ECEEESIECGPGQMCFNTRGSYQCV 3654
Score = 161 bits (408), Expect = 4e-39
Identities = 119/336 (35%), Positives = 157/336 (46%), Gaps = 53/336 (15%)
Query: 550 NECTVNPDICGAGHCINLPVRYTCICYEGYRFSEQQRKCVDIDECTQVQHLCSQG-RCEN 608
+EC+ P C C+N P R++C C G+ + R C D+DEC HLC +G RC N
Sbjct: 3354 DECSGGPSPCSHA-CLNAPGRFSCTCPTGFALAWDDRNCRDVDECAWDAHLCREGQRCVN 3412
Query: 609 TEGSFLCI--CPAGFMASEEGTNCIDVDECLRP-DVCGEGH-CVNTVGAFRCEYCDSGYR 664
GS+ C+ C GF + +G C DVDECL D C C NT G RC C GYR
Sbjct: 3413 LLGSYRCLPDCGPGFRVA-DGAGCEDVDECLEGLDDCHYNQLCENTPGGHRCS-CPRGYR 3470
Query: 665 MTQRG-RCEDIDECLN-PSTCPDEQCVNSPGSYQCV------------PCTEGFRGWNGQ 710
M C D++ECL P C QC N GSY+C+ CT R NGQ
Sbjct: 3471 MQGPSLPCLDVNECLQLPKACA-YQCHNLQGSYRCLCPPGQTLLRDGKACTSLER--NGQ 3527
Query: 711 CLDVDECLEPNVCANGDCSNLEG-SY-----------------MCSCHKGYTRTPDHKHC 752
+ P + +++ G SY C G+ R + C
Sbjct: 3528 NVTTVSHRGPLLPWLRPWASIPGTSYHAWVSLRPGPMALSSVGRAWCPPGFIR--QNGVC 3585
Query: 753 RDIDECQQGNLCVNGQCKNTEGSFRCTCGQGYQLSAAKDQCEDIDECQHRHL-CAHGQ-C 810
D+DEC+ NLC + C+NTEGS++C C GY+L + C+DI+EC+ + C GQ C
Sbjct: 3586 TDLDECRVRNLCQHA-CRNTEGSYQCLCPAGYRLLPSGKNCQDINECEEESIECGPGQMC 3644
Query: 811 RNTEGSFQCV---CDQGYRASGLGDHCEDINECLED 843
NT GS+QCV C YR C C +D
Sbjct: 3645 FNTRGSYQCVDTPCPATYRQGPSPGTC--FRRCSQD 3678
Score = 144 bits (363), Expect = 6e-34
Identities = 100/319 (31%), Positives = 143/319 (44%), Gaps = 50/319 (15%)
Query: 739 CHKGYTRTPDHKHCRDIDECQQGNLCVNGQCKNTEGSFRCTCGQGYQLSAAKDQCEDIDE 798
C +G+ C D DEC G + C N G F CTC G+ L+ C D+DE
Sbjct: 3337 CPEGFELDSQGAFCVDRDECSGGPSPCSHACLNAPGRFSCTCPTGFALAWDDRNCRDVDE 3396
Query: 799 CQ-HRHLCAHGQ-CRNTEGSFQCV--CDQGYRASGLGDHCEDINECLEDKSVCQRGD-CI 853
C HLC GQ C N GS++C+ C G+R + G CED++ECLE C C
Sbjct: 3397 CAWDAHLCREGQRCVNLLGSYRCLPDCGPGFRVAD-GAGCEDVDECLEGLDDCHYNQLCE 3455
Query: 854 NTAGSYDCTCPDGFQLDD-NKTCQDINEC-EHPGLCGPQGECLNTEGSFHCVCQQGFSIS 911
NT G + C+CP G+++ + C D+NEC + P C Q C N +GS+ C+C G ++
Sbjct: 3456 NTPGGHRCSCPRGYRMQGPSLPCLDVNECLQLPKACAYQ--CHNLQGSYRCLCPPGQTLL 3513
Query: 912 ADGRTCEDIDECVNNTVCDSH---------GFCDNTAGSF-----------------RCL 945
DG+ C ++ N SH + S+ R
Sbjct: 3514 RDGKACTSLERNGQNVTTVSHRGPLLPWLRPWASIPGTSYHAWVSLRPGPMALSSVGRAW 3573
Query: 946 CYQGFQAPQDGQGCVDVNECELLSGVCGEAFCENVEGSFLCVCADENQEYSPMTGQCRSR 1005
C GF Q+G C D++EC + +C A C N EGS+ C+C P C+
Sbjct: 3574 CPPGF-IRQNGV-CTDLDECR-VRNLCQHA-CRNTEGSYQCLC-PAGYRLLPSGKNCQ-- 3626
Query: 1006 TSTDLDVDVDQPKEEKKEC 1024
D+++ +EE EC
Sbjct: 3627 -------DINECEEESIEC 3638
Score = 125 bits (313), Expect = 4e-28
Identities = 104/333 (31%), Positives = 141/333 (42%), Gaps = 39/333 (11%)
Query: 863 CPDGFQLDDNKT-CQDINECEH-PGLCGPQGECLNTEGSFHCVCQQGFSISADGRTCEDI 920
CP+GF+LD C D +EC P C CLN G F C C GF+++ D R C D+
Sbjct: 3337 CPEGFELDSQGAFCVDRDECSGGPSPCSHA--CLNAPGRFSCTCPTGFALAWDDRNCRDV 3394
Query: 921 DECVNNT-VCDSHGFCDNTAGSFRCL--CYQGFQAPQDGQGCVDVNEC-ELLSGVCGEAF 976
DEC + +C C N GS+RCL C GF+ DG GC DV+EC E L
Sbjct: 3395 DECAWDAHLCREGQRCVNLLGSYRCLPDCGPGFRVA-DGAGCEDVDECLEGLDDCHYNQL 3453
Query: 977 CENVEGSFLCVCADENQEYSPMTGQCRSRTSTDLDVDVDQPKEEKKECYYNLNDASLCDN 1036
CEN G C C + P S D++ + PK +C+ NL + C
Sbjct: 3454 CENTPGGHRCSCPRGYRMQGP------SLPCLDVNECLQLPKACAYQCH-NLQGSYRCLC 3506
Query: 1037 VLAPNVTKQECCCTSGAGWGDNCE-------IFP-----CPVLGTA--EFTEMCPKGKGF 1082
+ + CTS G N + P + GT+ + + P
Sbjct: 3507 PPGQTLLRDGKACTSLERNGQNVTTVSHRGPLLPWLRPWASIPGTSYHAWVSLRPGPMAL 3566
Query: 1083 VPAGESSSEAGGENYK----DADECLLFGQEICKNGFCLNTRPGYECYCKQGTYYDPVKL 1138
G + G D DEC + + +C++ C NT Y+C C G P
Sbjct: 3567 SSVGRAWCPPGFIRQNGVCTDLDECRV--RNLCQHA-CRNTEGSYQCLCPAGYRLLPSGK 3623
Query: 1139 QCFDMDECQDPS-SCIDGQ-CVNTEGSYNCFCT 1169
C D++EC++ S C GQ C NT GSY C T
Sbjct: 3624 NCQDINECEEESIECGPGQMCFNTRGSYQCVDT 3656
Score = 100 bits (248), Expect = 1e-20
Identities = 76/255 (29%), Positives = 111/255 (43%), Gaps = 50/255 (19%)
Query: 548 EINECTVNPDICGAGH-CINLPVRYTCICYEGYRFSEQQRKCVDIDECTQVQHLCSQGRC 606
+++EC D C C N P + C C GYR C+D++EC Q+ C+ +C
Sbjct: 3437 DVDECLEGLDDCHYNQLCENTPGGHRCSCPRGYRMQGPSLPCLDVNECLQLPKACAY-QC 3495
Query: 607 ENTEGSFLCICPAGFMASEEGTNCIDVDE----------------CLRP--DVCGEGH-- 646
N +GS+ C+CP G +G C ++ LRP + G +
Sbjct: 3496 HNLQGSYRCLCPPGQTLLRDGKACTSLERNGQNVTTVSHRGPLLPWLRPWASIPGTSYHA 3555
Query: 647 ---------CVNTVGAFRCEYCDSGYRMTQRGRCEDIDECLNPSTCPDEQCVNSPGSYQC 697
+++VG +C G+ + Q G C D+DEC + C C N+ GSYQC
Sbjct: 3556 WVSLRPGPMALSSVGR---AWCPPGF-IRQNGVCTDLDECRVRNLC-QHACRNTEGSYQC 3610
Query: 698 VPCTEGFR----GWNGQCLDVDECLEPNV-CANGD-CSNLEGSYMC---SCHKGYTRTPD 748
+ C G+R G N C D++EC E ++ C G C N GSY C C Y + P
Sbjct: 3611 L-CPAGYRLLPSGKN--CQDINECEEESIECGPGQMCFNTRGSYQCVDTPCPATYRQGPS 3667
Query: 749 HKHC--RDIDECQQG 761
C R +C G
Sbjct: 3668 PGTCFRRCSQDCGTG 3682
Score = 71.2 bits (173), Expect = 6e-12
Identities = 69/237 (29%), Positives = 85/237 (35%), Gaps = 55/237 (23%)
Query: 946 CYQGFQAPQDGQGCVDVNECELLSGVCGEAFCENVEGSFLCVCADENQEYSPMTGQCRSR 1005
C +GF+ G CVD +EC C A C N G F C C
Sbjct: 3337 CPEGFELDSQGAFCVDRDECSGGPSPCSHA-CLNAPGRFSCTCP---------------- 3379
Query: 1006 TSTDLDVDVDQPKEEKKECYYNLNDASLCDNVLAPNVTKQECCCTSGAGWGDNCEIFPCP 1065
T L D D+ + EC + DA LC G C
Sbjct: 3380 TGFALAWD-DRNCRDVDECAW---DAHLCRE-------------------GQRC----VN 3412
Query: 1066 VLGTAEFTEMCPKGKGFVPAGESSSEAGGENYKDADECLLFGQEICKNGFCLNTRPGYEC 1125
+LG+ C G GF A G +D DECL + N C NT G+ C
Sbjct: 3413 LLGSYRCLPDC--GPGF-------RVADGAGCEDVDECLEGLDDCHYNQLCENTPGGHRC 3463
Query: 1126 YCKQGTYYDPVKLQCFDMDEC-QDPSSCIDGQCVNTEGSYNCFCTHPMVLDASEKRC 1181
C +G L C D++EC Q P +C QC N +GSY C C L K C
Sbjct: 3464 SCPRGYRMQGPSLPCLDVNECLQLPKACAY-QCHNLQGSYRCLCPPGQTLLRDGKAC 3519
Score = 68.2 bits (165), Expect = 5e-11
Identities = 90/334 (26%), Positives = 118/334 (35%), Gaps = 66/334 (19%)
Query: 1099 DADECLLFGQEICKNGFCLNTRPGYECYCKQGTYYDPVKLQCFDMDECQ-DPSSCIDGQ- 1156
D DEC G C + CLN + C C G C D+DEC D C +GQ
Sbjct: 3352 DRDECS-GGPSPCSHA-CLNAPGRFSCTCPTGFALAWDDRNCRDVDECAWDAHLCREGQR 3409
Query: 1157 CVNTEGSYNCFCT-HPMVLDASEKRCIRPAESNEQIEETDVYQDLCWEHLSDEYVCSRPL 1215
CVN GSY C P A C E E +++ Y LC E+ + CS P
Sbjct: 3410 CVNLLGSYRCLPDCGPGFRVADGAGCEDVDECLEGLDDCH-YNQLC-ENTPGGHRCSCPR 3467
Query: 1216 VGK-QTTYTEC-----CCLYGEAWGMQC--------ALCP-----LKDSDDYAQL----C 1252
+ Q C C +A QC LCP L+D L
Sbjct: 3468 GYRMQGPSLPCLDVNECLQLPKACAYQCHNLQGSYRCLCPPGQTLLRDGKACTSLERNGQ 3527
Query: 1253 NIPVTGRRQPY-----------------------GRDALVDFSEQYTPEADPYFIQDRFL 1289
N+ R P G AL + P P FI+ +
Sbjct: 3528 NVTTVSHRGPLLPWLRPWASIPGTSYHAWVSLRPGPMALSSVGRAWCP---PGFIRQNGV 3584
Query: 1290 NSFEELQAEECGILNGCENGRCVRVQEGYTCDCFDGYHLDTAKMTCVDVNECDELNNRMS 1349
+ +EC + N C++ C + Y C C GY L + C D+NEC+E +
Sbjct: 3585 CT----DLDECRVRNLCQHA-CRNTEGSYQCLCPAGYRLLPSGKNCQDINECEE--ESIE 3637
Query: 1350 LCKNAKCINTDGSYKCL---CLPGYVPSDKPNYC 1380
C NT GSY+C+ C Y P C
Sbjct: 3638 CGPGQMCFNTRGSYQCVDTPCPATYRQGPSPGTC 3671
Score = 55.1 bits (131), Expect = 5e-07
Identities = 30/88 (34%), Positives = 43/88 (48%), Gaps = 6/88 (6%)
Query: 547 TEINECTVNPDICGAGHCINLPVRYTCICYEGYRFSEQQRKCVDIDECTQVQHLCSQGR- 605
T+++EC V ++C C N Y C+C GYR + C DI+EC + C G+
Sbjct: 3586 TDLDECRVR-NLCQHA-CRNTEGSYQCLCPAGYRLLPSGKNCQDINECEEESIECGPGQM 3643
Query: 606 CENTEGSFLCI---CPAGFMASEEGTNC 630
C NT GS+ C+ CPA + C
Sbjct: 3644 CFNTRGSYQCVDTPCPATYRQGPSPGTC 3671
Score = 54.3 bits (129), Expect = 8e-07
Identities = 29/82 (35%), Positives = 38/82 (46%), Gaps = 5/82 (6%)
Query: 1303 LNGCE-NGRCVRVQEGYTCDCFDGYHLDTAKMTCVDVNECDELNNRMSLCKNAKCINTDG 1361
L+ C N C G+ C C GY + + C+DVNEC +L + +C N G
Sbjct: 3445 LDDCHYNQLCENTPGGHRCSCPRGYRMQGPSLPCLDVNECLQLPKACAY----QCHNLQG 3500
Query: 1362 SYKCLCLPGYVPSDKPNYCTPL 1383
SY+CLC PG CT L
Sbjct: 3501 SYRCLCPPGQTLLRDGKACTSL 3522
Score = 48.9 bits (115), Expect = 3e-05
Identities = 46/181 (25%), Positives = 73/181 (40%), Gaps = 23/181 (12%)
Query: 286 CLPGYKRVNNTFCQDINECQLQGVCPNGECLNTMGSYRCTCKIGFGPDPTFSSCVPDPPV 345
C PG+ R N C D++EC+++ +C + C NT GSY+C C G+ P+ +C D
Sbjct: 3574 CPPGFIRQNGV-CTDLDECRVRNLCQHA-CRNTEGSYQCLCPAGYRLLPSGKNC-QDINE 3630
Query: 346 ISEEKGPCYRLVSSGRQCMHPLSVHLTKQLCCCSVGKAWGPHCEKCPLPGTAAFKEICPG 405
EE C G+ C + + C + + + P PGT +
Sbjct: 3631 CEEESIEC----GPGQMCFNTRGSYQCVDTPCPATYR-------QGPSPGTCFRRCSQDC 3679
Query: 406 GMGYTVSGVHRRRPI------HHHVGKGPVFVK---PKNTQPVAKSTHPPPLPAKEEPVE 456
G G + +R P+ HH V + F + P N ++ P P P+
Sbjct: 3680 GTGGPSTLQYRLLPLPLGVRAHHDVARLTAFSEVGVPANRTELSMLEPDPRSPFALRPLR 3739
Query: 457 A 457
A
Sbjct: 3740 A 3740
Score = 42.7 bits (99), Expect = 0.002
Identities = 32/125 (25%), Positives = 57/125 (45%), Gaps = 9/125 (7%)
Query: 262 SWGFNKCQKCPKKPSYHG-YNQMMECLPGYKRVNNTFCQDINECQLQGVCP---NGECLN 317
+W + C++ + + G Y + +C PG++ + C+D++EC L+G+ N C N
Sbjct: 3398 AWDAHLCREGQRCVNLLGSYRCLPDCGPGFRVADGAGCEDVDEC-LEGLDDCHYNQLCEN 3456
Query: 318 TMGSYRCTCKIGFGPDPTFSSCVPDPPVISEEKG---PCYRLVSSGRQCMHPLSVHLTKQ 374
T G +RC+C G+ C+ + K C+ L S R C+ P L +
Sbjct: 3457 TPGGHRCSCPRGYRMQGPSLPCLDVNECLQLPKACAYQCHNLQGSYR-CLCPPGQTLLRD 3515
Query: 375 LCCCS 379
C+
Sbjct: 3516 GKACT 3520
Score = 42.7 bits (99), Expect = 0.002
Identities = 29/87 (33%), Positives = 36/87 (41%), Gaps = 5/87 (5%)
Query: 1307 ENGRCVRVQEGYTC--DCFDGYHLDTAKMTCVDVNECDELNNRMSLCKNAKCINTDGSYK 1364
E RCV + Y C DC G+ + C DV+EC L N C NT G ++
Sbjct: 3406 EGQRCVNLLGSYRCLPDCGPGFRVADGA-GCEDVDEC--LEGLDDCHYNQLCENTPGGHR 3462
Query: 1365 CLCLPGYVPSDKPNYCTPLNTALNLEK 1391
C C GY C +N L L K
Sbjct: 3463 CSCPRGYRMQGPSLPCLDVNECLQLPK 3489
Score = 37.0 bits (84), Expect = 0.13
Identities = 18/50 (36%), Positives = 27/50 (54%), Gaps = 4/50 (8%)
Query: 1322 CFDGYHLDTAKMTCVDVNECDELNNRMSLCKNAKCINTDGSYKCLCLPGY 1371
C +G+ LD+ CVD +EC + S C +A C+N G + C C G+
Sbjct: 3337 CPEGFELDSQGAFCVDRDEC---SGGPSPCSHA-CLNAPGRFSCTCPTGF 3382
>gi|10190748 CEGP1 protein [Homo sapiens]
Length = 999
Score = 188 bits (478), Expect = 3e-47
Identities = 138/449 (30%), Positives = 188/449 (41%), Gaps = 87/449 (19%)
Query: 548 EINECTVNPDICGAGH-CINLPVRYTCICYEGYRFSEQQRKCVDIDECTQVQHLCSQGRC 606
+++EC D C A C N P Y C C GY+ + R+C DIDEC + C
Sbjct: 45 DVDECAQGLDDCHADALCQNTPTSYKCSCKPGYQ--GEGRQCEDIDECGNELNGGCVHDC 102
Query: 607 ENTEGSFLCICPAGFMASEEGTNCIDVDECLRPDVCGEGHCVNTVGAFRCEYCDSGYRMT 666
N G++ C C GFM + +G NC+DVDECL + + CVN +G++ C C G+ ++
Sbjct: 103 LNIPGNYRCTCFDGFMLAHDGHNCLDVDECLENNGGCQHTCVNVMGSYEC-CCKEGFFLS 161
Query: 667 QR-----GRCEDIDECLNPSTCPDEQCVNSP-GSYQC----------------VPCTEGF 704
R E+ C+N C +P GS C + C G
Sbjct: 162 DNQHTCIHRSEEGLSCMNKDHGCSHICKEAPRGSVACECRPGFELAKNQRDCILTCNHGN 221
Query: 705 RGWNGQCLDVDE------------------CLE--------------------------- 719
G C D + CLE
Sbjct: 222 GGCQHSCDDTADGPECSCHPQYKMHTDGRSCLEREDTVLEVTESNTTSVVDGDKRVKRRL 281
Query: 720 -PNVCA--NGDC----SNLEGSYMCSCHKGYTRTPDHKHCRDIDECQQGNLCVNGQCKNT 772
CA NG C + CSC G+T D K C+DIDECQ N + CKN
Sbjct: 282 LMETCAVNNGGCDRTCKDTSTGVHCSCPVGFTLQLDGKTCKDIDECQTRNGGCDHFCKNI 341
Query: 773 EGSFRCTCGQGYQLSAAKDQCEDIDECQHRHLCAHGQCRNTEGSFQCVCDQGYRASGLGD 832
GSF C C +G++L + C+D+DEC C H C N G+F C C++GY G
Sbjct: 342 VGSFDCGCKKGFKLLTDEKSCQDVDECSLDRTCDH-SCINHPGTFACACNRGYTLYGF-T 399
Query: 833 HCEDINECLEDKSVCQRGDCINTAGSYDCTCPDGFQLDDN-KTCQDINECEHPGLCGPQG 891
HC D NEC + CQ+ C+NT GSY+C C G++L N K C ++ P P+
Sbjct: 400 HCGDTNECSINNGGCQQ-VCVNTVGSYECQCHPGYKLHWNKKDCVEVKGL-LPTSVSPRV 457
Query: 892 --ECLNTEGSFHCV--CQQGFSISADGRT 916
C + G C C G +S+D T
Sbjct: 458 SLHCGKSGGGDGCFLRCHSGIHLSSDVTT 486
Score = 180 bits (456), Expect = 1e-44
Identities = 132/441 (29%), Positives = 190/441 (43%), Gaps = 61/441 (13%)
Query: 669 GRCEDIDECLNP-STC-PDEQCVNSPGSYQCVPCTEGFRGWNGQCLDVDEC-LEPNVCAN 725
G ED+DEC C D C N+P SY+C C G++G QC D+DEC E N
Sbjct: 41 GPQEDVDECAQGLDDCHADALCQNTPTSYKC-SCKPGYQGEGRQCEDIDECGNELNGGCV 99
Query: 726 GDCSNLEGSYMCSCHKGYTRTPDHKHCRDIDECQQGNLCVNGQCKNTEGSFRCTCGQGYQ 785
DC N+ G+Y C+C G+ D +C D+DEC + N C N GS+ C C +G+
Sbjct: 100 HDCLNIPGNYRCTCFDGFMLAHDGHNCLDVDECLENNGGCQHTCVNVMGSYECCCKEGFF 159
Query: 786 LSAAKDQC----EDIDECQHR-HLCAHGQCRNTEGSFQCVCDQGYRASGLGDHCEDINEC 840
LS + C E+ C ++ H C+H GS C C G+ + C I C
Sbjct: 160 LSDNQHTCIHRSEEGLSCMNKDHGCSHICKEAPRGSVACECRPGFELAKNQRDC--ILTC 217
Query: 841 LEDKSVCQRGDCINTAGSYDCTCPDGFQLD-DNKTCQD-------INECEHPGLC----- 887
CQ C +TA +C+C +++ D ++C + + E +
Sbjct: 218 NHGNGGCQHS-CDDTADGPECSCHPQYKMHTDGRSCLEREDTVLEVTESNTTSVVDGDKR 276
Query: 888 ---------------GPQGECLNTEGSFHCVCQQGFSISADGRTCEDIDEC-VNNTVCDS 931
G C +T HC C GF++ DG+TC+DIDEC N CD
Sbjct: 277 VKRRLLMETCAVNNGGCDRTCKDTSTGVHCSCPVGFTLQLDGKTCKDIDECQTRNGGCDH 336
Query: 932 HGFCDNTAGSFRCLCYQGFQAPQDGQGCVDVNECELLSGVCGEAFCENVEGSFLCVCADE 991
FC N GSF C C +GF+ D + C DV+EC L C + C N G+F C C
Sbjct: 337 --FCKNIVGSFDCGCKKGFKLLTDEKSCQDVDECS-LDRTCDHS-CINHPGTFACAC--- 389
Query: 992 NQEYSPM-------TGQCRSRTSTDLDVDVDQPKEEKKEC------YYNLNDASLCDNVL 1038
N+ Y+ T +C V V+ + +C ++N D +L
Sbjct: 390 NRGYTLYGFTHCGDTNECSINNGGCQQVCVNTVGSYECQCHPGYKLHWNKKDCVEVKGLL 449
Query: 1039 APNVTKQECCCTSGAGWGDNC 1059
+V+ + +G GD C
Sbjct: 450 PTSVSPRVSLHCGKSGGGDGC 470
Score = 147 bits (370), Expect = 9e-35
Identities = 125/424 (29%), Positives = 180/424 (42%), Gaps = 59/424 (13%)
Query: 794 EDIDECQHRHLCAHGQ--CRNTEGSFQCVCDQGYRASGLGDHCEDINECLEDKSVCQRGD 851
ED+DEC H C+NT S++C C GY+ G G CEDI+EC + + D
Sbjct: 44 EDVDECAQGLDDCHADALCQNTPTSYKCSCKPGYQ--GEGRQCEDIDECGNELNGGCVHD 101
Query: 852 CINTAGSYDCTCPDGFQL-DDNKTCQDINEC-EHPGLCGPQGECLNTEGSFHCVCQQGFS 909
C+N G+Y CTC DGF L D C D++EC E+ G C Q C+N GS+ C C++GF
Sbjct: 102 CLNIPGNYRCTCFDGFMLAHDGHNCLDVDECLENNGGC--QHTCVNVMGSYECCCKEGFF 159
Query: 910 ISADGRTC----EDIDECVNNTVCDSHGFCDNTAGSFRCLCYQGFQAPQDGQGCVDVNEC 965
+S + TC E+ C+N SH + GS C C GF+ ++ + C+ C
Sbjct: 160 LSDNQHTCIHRSEEGLSCMNKDHGCSHICKEAPRGSVACECRPGFELAKNQRDCILT--C 217
Query: 966 ELLSGVCGEAFCENVEGSFLCVCADENQEYSPMTGQCRSRTSTDLDVD-------VDQPK 1018
+G C + C++ C C + + ++ C R T L+V VD K
Sbjct: 218 NHGNGGCQHS-CDDTADGPECSCHPQYKMHTDGRS-CLEREDTVLEVTESNTTSVVDGDK 275
Query: 1019 EEKKECYYN---LNDASLCDNVLAPNVTKQECCCTSGAGW----------------GDNC 1059
K+ +N+ CD T C C G C
Sbjct: 276 RVKRRLLMETCAVNNGG-CDRTCKDTSTGVHCSCPVGFTLQLDGKTCKDIDECQTRNGGC 334
Query: 1060 EIFPCPVLGTAEFTEMCPKGKGFVPAGESSSEAGGENYKDADECLLFGQEICKNGFCLNT 1119
+ F ++G+ + C KGF + S +D DEC L C + C+N
Sbjct: 335 DHFCKNIVGSFD----CGCKKGFKLLTDEKS------CQDVDECSL--DRTCDHS-CINH 381
Query: 1120 RPGYECYCKQG-TYYDPVKLQCFDMDECQDPSSCIDGQCVNTEGSYNCFCTHPMVLDASE 1178
+ C C +G T Y C D +EC + CVNT GSY C C L ++
Sbjct: 382 PGTFACACNRGYTLYGFT--HCGDTNECSINNGGCQQVCVNTVGSYECQCHPGYKLHWNK 439
Query: 1179 KRCI 1182
K C+
Sbjct: 440 KDCV 443
Score = 86.7 bits (213), Expect = 1e-16
Identities = 114/468 (24%), Positives = 174/468 (37%), Gaps = 92/468 (19%)
Query: 918 EDIDECVNNTV-CDSHGFCDNTAGSFRCLCYQGFQAPQDGQGCVDVNEC-ELLSGVCGEA 975
ED+DEC C + C NT S++C C G+Q +G+ C D++EC L+G C
Sbjct: 44 EDVDECAQGLDDCHADALCQNTPTSYKCSCKPGYQG--EGRQCEDIDECGNELNGGCVHD 101
Query: 976 FCENVEGSFLCVCADENQEYSPMTGQCRSRTSTDLDVDVDQPKEEKKECYYNLNDASLCD 1035
C N+ G++ C C D G + + +DVD+ E C + C
Sbjct: 102 -CLNIPGNYRCTCFD---------GFMLAHDGHNC-LDVDECLENNGGCQHT------CV 144
Query: 1036 NVLAPNVTKQECCCTSGAGWGDN---CEIFPCPVLGTAEFTEMCPKGKGFVPAGESSSEA 1092
NV+ ECCC G DN C L C P G + E
Sbjct: 145 NVMG----SYECCCKEGFFLSDNQHTCIHRSEEGLSCMNKDHGCSHICKEAPRGSVACEC 200
Query: 1093 --GGENYKDADECLL---FGQEICKNGFCLNTRPGYECYCKQGTYYDPVKLQCFDMDECQ 1147
G E K+ +C+L G C++ C +T G EC
Sbjct: 201 RPGFELAKNQRDCILTCNHGNGGCQHS-CDDTADGPEC---------------------- 237
Query: 1148 DPSSCIDGQCVNTEGSYNCFCTHPMVLDASEKRCIRPAESNEQIEETDVYQDLCWEHLSD 1207
SC ++T+G +C VL+ +E + +++++ + + +
Sbjct: 238 ---SCHPQYKMHTDGR-SCLEREDTVLEVTESNTTSVVDGDKRVKRRLLMETCAVNNGGC 293
Query: 1208 EYVCSRPLVGKQTTYTECCCLYGEAWGMQCALCPLKDSDDYAQLCNIPVTGRRQPYGRDA 1267
+ C G C C G + C KD D+ Q N G + ++
Sbjct: 294 DRTCKDTSTG-----VHCSCPVGFTLQLDGKTC--KDIDE-CQTRN----GGCDHFCKNI 341
Query: 1268 LVDFS----EQYTPEADPYFIQDRFLNSFEELQAEECGILNGCENGRCVRVQEGYTCDCF 1323
+ F + + D QD +EC + C++ C+ + C C
Sbjct: 342 VGSFDCGCKKGFKLLTDEKSCQD----------VDECSLDRTCDHS-CINHPGTFACACN 390
Query: 1324 DGYHLDTAKMTCVDVNECDELNNRMSLCKNAKCINTDGSYKCLCLPGY 1371
GY L C D NEC +NN C+ C+NT GSY+C C PGY
Sbjct: 391 RGYTL-YGFTHCGDTNECS-INN--GGCQQV-CVNTVGSYECQCHPGY 433
Score = 79.0 bits (193), Expect = 3e-14
Identities = 92/369 (24%), Positives = 124/369 (33%), Gaps = 71/369 (19%)
Query: 1017 PKEEKKECYYNLNDA---SLCDNVLAPNVTKQECCCTSG-AGWGDNCEIFPCPVLGTAEF 1072
P+E+ EC L+D +LC N T +C C G G G CE
Sbjct: 42 PQEDVDECAQGLDDCHADALCQNT----PTSYKCSCKPGYQGEGRQCE------------ 85
Query: 1073 TEMCPKGKGFVPAGESSSEAGGENYKDADECLLFGQEICKNGFC----LNTRPGYECYCK 1128
D DEC G E+ NG C LN Y C C
Sbjct: 86 --------------------------DIDEC---GNEL--NGGCVHDCLNIPGNYRCTCF 114
Query: 1129 QGTYYDPVKLQCFDMDECQDPSSCIDGQCVNTEGSYNCFCTHPMVLDASEKRCIRPAESN 1188
G C D+DEC + + CVN GSY C C L ++ CI +E
Sbjct: 115 DGFMLAHDGHNCLDVDECLENNGGCQHTCVNVMGSYECCCKEGFFLSDNQHTCIHRSEEG 174
Query: 1189 EQIEETD-VYQDLCWEHLSDEYVCS-RPLVGKQTTYTEC--CCLYGEAWGMQCALCPLKD 1244
D +C E C RP +C C +G G Q + D
Sbjct: 175 LSCMNKDHGCSHICKEAPRGSVACECRPGFELAKNQRDCILTCNHGNG-GCQHSCDDTAD 233
Query: 1245 SDDYA--QLCNIPVTGRRQPYGRDALVDFSEQYTPEADPYFIQDRFLNSFEELQAEECGI 1302
+ + + GR D +++ +E T + D L E C +
Sbjct: 234 GPECSCHPQYKMHTDGRSCLEREDTVLEVTESNTTS-----VVDGDKRVKRRLLMETCAV 288
Query: 1303 LNGCENGRCVRVQEGYTCDCFDGYHLDTAKMTCVDVNECDELNNRMSLCKNAKCINTDGS 1362
NG + C G C C G+ L TC D++EC N C + C N GS
Sbjct: 289 NNGGCDRTCKDTSTGVHCSCPVGFTLQLDGKTCKDIDECQTRNGG---CDHF-CKNIVGS 344
Query: 1363 YKCLCLPGY 1371
+ C C G+
Sbjct: 345 FDCGCKKGF 353
Score = 60.8 bits (146), Expect = 9e-09
Identities = 33/84 (39%), Positives = 45/84 (53%), Gaps = 5/84 (5%)
Query: 1298 EECGI-LNGCENGRCVRVQEGYTCDCFDGYHLDTAKMTCVDVNECDELNNRMSLCKNAKC 1356
+ECG LNG C+ + Y C CFDG+ L C+DV+EC E N C++ C
Sbjct: 88 DECGNELNGGCVHDCLNIPGNYRCTCFDGFMLAHDGHNCLDVDECLENNGG---CQHT-C 143
Query: 1357 INTDGSYKCLCLPGYVPSDKPNYC 1380
+N GSY+C C G+ SD + C
Sbjct: 144 VNVMGSYECCCKEGFFLSDNQHTC 167
Score = 54.3 bits (129), Expect = 8e-07
Identities = 108/464 (23%), Positives = 157/464 (33%), Gaps = 80/464 (17%)
Query: 548 EINECTVNPDICGAGHCINLPVRYTCICYEGYRFSEQQRKCVDIDECTQVQHLCSQGRCE 607
+++EC++ D CIN P + C C GY C D +EC+ C Q C
Sbjct: 364 DVDECSL--DRTCDHSCINHPGTFACACNRGYTLYGFTH-CGDTNECSINNGGCQQV-CV 419
Query: 608 NTEGSFLCICPAGFMASEEGTNCIDVDECLRPDVCGEG--HCVNTVGAFRCEY-CDSGYR 664
NT GS+ C C G+ +C++V L V HC + G C C SG
Sbjct: 420 NTVGSYECQCHPGYKLHWNKKDCVEVKGLLPTSVSPRVSLHCGKSGGGDGCFLRCHSGIH 479
Query: 665 MTQ--------------RGRC-----EDIDECLNPSTCPDEQCVNSPGSYQCVPCTEGFR 705
++ G+C E E L P+ V Y + C+ G +
Sbjct: 480 LSSDVTTIRTSVTFKLNEGKCSLKNAELFPEGLRPALPEKHSSVKESFRYVNLTCSSGKQ 539
Query: 706 --GWNGQ-------CLDVDECLEPN---VCANGDCSNLEGSYMCSCHKGYTRTPDHKHCR 753
G G+ + V+ LE N V A+ D S + K H R
Sbjct: 540 VPGAPGRPSTPKEMFITVEFELETNQKEVTASCDLSCIVKRTEKRLRKAIRTLRKAVH-R 598
Query: 754 DIDECQQGNLCVNGQCKNTEGSFR----CTCGQGYQLSAAKDQCEDI------DECQHRH 803
+ Q + ++ K S R C GQG+ A++QC D + R
Sbjct: 599 EQFHLQLSGMNLDVAKKPPRTSERQAESCGVGQGH----AENQCVSCRAGTYYDGARERC 654
Query: 804 -LCAHGQCRNTEGSFQC------------VCDQGYRASGLGDHCEDINECLEDKSVCQ-- 848
LC +G +N EG C + + S G C+ + + CQ
Sbjct: 655 ILCPNGTFQNEEGQMTCEPCPRPGNSGALKTPEAWNMSECGGLCQPGEYSADGFAPCQLC 714
Query: 849 -RGDCINTAGSYDCTCPDGFQLDDNKTCQDINECEHPGLCGPQGECLNTE---------G 898
G AG C G ++ +CE C P G NT G
Sbjct: 715 ALGTFQPEAGRTSCFPCGGGLATKHQGATSFQDCETRVQCSP-GHFYNTTTHRCIRCPVG 773
Query: 899 SFHCVCQQGFSISADGRTCEDIDECVNNTVCDSHGFCDNTAGSF 942
++ + +S G T D D N T C + C G F
Sbjct: 774 TYQPEFGKNNCVSCPGNTTTDFDGSTNITQCKNRR-CGGELGDF 816
Score = 48.9 bits (115), Expect = 3e-05
Identities = 121/556 (21%), Positives = 180/556 (32%), Gaps = 141/556 (25%)
Query: 286 CLPGYKRVNNT-FCQDINECQLQGVCPNGECLNTMGSYRCTCKIGFGPDPTFSSCVPDPP 344
C G+K + + CQD++EC L C + C+N G++ C C G+ F+ C D
Sbjct: 349 CKKGFKLLTDEKSCQDVDECSLDRTCDHS-CINHPGTFACACNRGY-TLYGFTHC-GDTN 405
Query: 345 VISEEKGPCYRLV-----SSGRQCMHPLSVHLTKQLCC-------CSVGKAWGPHCEKCP 392
S G C ++ S QC +H K+ C SV HC K
Sbjct: 406 ECSINNGGCQQVCVNTVGSYECQCHPGYKLHWNKKDCVEVKGLLPTSVSPRVSLHCGKSG 465
Query: 393 LPGTAAFKEICPGGMGYTVSGVHRRRPIHHHVGKGPVFVKPKNTQPVAKSTHPPPLPAKE 452
G F C G+ + R + + +G +K P P LP K
Sbjct: 466 -GGDGCFLR-CHSGIHLSSDVTTIRTSVTFKLNEGKCSLKNAELFPEGLR---PALPEKH 520
Query: 453 EPV-EALTF------SREHGPGV----AEPEVATAPPEKEIPSLDQEKTK-------LEP 494
V E+ + S + PG + P+ E E+ + +E T ++
Sbjct: 521 SSVKESFRYVNLTCSSGKQVPGAPGRPSTPKEMFITVEFELETNQKEVTASCDLSCIVKR 580
Query: 495 GQPQLSPGISTI-------HLHPQFPGIVIEKTSPPVPVEVAPEASTSSASQVIAPTQVT 547
+ +L I T+ H Q G+ ++ P P S A
Sbjct: 581 TEKRLRKAIRTLRKAVHREQFHLQLSGMNLDVAKKP------PRTSERQA---------- 624
Query: 548 EINECTVNPDICGAGHCINLPVRYTCICYEGYRFSEQQRKCVDIDECTQVQHLCSQGRCE 607
C V G GH N V C G + + +C+ LC G +
Sbjct: 625 --ESCGV-----GQGHAENQCVS----CRAGTYYDGARERCI----------LCPNGTFQ 663
Query: 608 NTEGSFLC-ICP----AGFMASEEGTNCIDVDECLRP-----------DVCGEGHCVNTV 651
N EG C CP +G + + E N + +P +C G
Sbjct: 664 NEEGQMTCEPCPRPGNSGALKTPEAWNMSECGGLCQPGEYSADGFAPCQLCALGTFQPEA 723
Query: 652 GAFRCEYCDSGYRMTQRGR-----CEDIDEC-----LNPSTCPDEQCVNSP-GSYQ---- 696
G C C G +G CE +C N +T +C+ P G+YQ
Sbjct: 724 GRTSCFPCGGGLATKHQGATSFQDCETRVQCSPGHFYNTTT---HRCIRCPVGTYQPEFG 780
Query: 697 ---CVPCTEGFRGWNGQCLDVDECLEPNVCANGDCSNLEGSYMCSCHKGYTRTPDHKHCR 753
CV C D D C N C G + GY +P++
Sbjct: 781 KNNCVSCP------GNTTTDFDGSTNITQCKNRRCGGELGDF-----TGYIESPNY---- 825
Query: 754 DIDECQQGNLCVNGQC 769
GN N +C
Sbjct: 826 ------PGNYPANTEC 835
Score = 47.8 bits (112), Expect = 8e-05
Identities = 31/98 (31%), Positives = 42/98 (42%), Gaps = 15/98 (15%)
Query: 286 CLPGYKRVNNTFCQDINEC--QLQGVCPNGECLNTMGSYRCTCKIGFGPDPTFSSCVPDP 343
C PGY+ C+DI+EC +L G C + +CLN G+YRCTC GF +C+
Sbjct: 73 CKPGYQGEGRQ-CEDIDECGNELNGGCVH-DCLNIPGNYRCTCFDGFMLAHDGHNCLDVD 130
Query: 344 PVISEEKGPCYRLVSSGRQCMHPLSVHLTKQLCCCSVG 381
+ G C H + CCC G
Sbjct: 131 ECLENNGG-----------CQHTCVNVMGSYECCCKEG 157
Score = 42.4 bits (98), Expect = 0.003
Identities = 27/93 (29%), Positives = 45/93 (48%), Gaps = 9/93 (9%)
Query: 1298 EECGI-LNGCE-NGRCVRVQEGYTCDCFDGYHLDTAKMTCVDVNEC-DELNNRMSLCKNA 1354
+EC L+ C + C Y C C GY + + C D++EC +ELN C +
Sbjct: 47 DECAQGLDDCHADALCQNTPTSYKCSCKPGYQGEGRQ--CEDIDECGNELNGG---CVH- 100
Query: 1355 KCINTDGSYKCLCLPGYVPSDKPNYCTPLNTAL 1387
C+N G+Y+C C G++ + + C ++ L
Sbjct: 101 DCLNIPGNYRCTCFDGFMLAHDGHNCLDVDECL 133
Score = 40.0 bits (92), Expect = 0.016
Identities = 25/87 (28%), Positives = 37/87 (42%), Gaps = 17/87 (19%)
Query: 281 NQMMECLPGYKRVNNTF-CQDINEC-QLQGVCPNGECLNTMGSYRCTCKIGFGPDPTFSS 338
N C G+ ++ C D++EC + G C + C+N MGSY C CK GF
Sbjct: 108 NYRCTCFDGFMLAHDGHNCLDVDECLENNGGCQH-TCVNVMGSYECCCKEGF-------- 158
Query: 339 CVPDPPVISEEKGPCYRLVSSGRQCMH 365
+S+ + C G CM+
Sbjct: 159 ------FLSDNQHTCIHRSEEGLSCMN 179
Score = 38.1 bits (87), Expect = 0.060
Identities = 26/84 (30%), Positives = 35/84 (41%), Gaps = 12/84 (14%)
Query: 298 CQDINECQLQGVCPNGECLNTMGSYRCTCKIGFGPDPTFSSCVPDPPVISEEKGPCYRLV 357
C+DI+ECQ + + C N +GS+ C CK GF SC ++ C
Sbjct: 321 CKDIDECQTRNGGCDHFCKNIVGSFDCGCKKGFKLLTDEKSC--------QDVDEC---- 368
Query: 358 SSGRQCMHPLSVHLTKQLCCCSVG 381
S R C H H C C+ G
Sbjct: 369 SLDRTCDHSCINHPGTFACACNRG 392
Database: hs.faa
Posted date: Aug 4, 2009 4:42 PM
Number of letters in database: 18,247,518
Number of sequences in database: 37,866
Lambda K H
0.319 0.137 0.456
Gapped
Lambda K H
0.267 0.0410 0.140
Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Hits to DB: 69,317,031
Number of Sequences: 37866
Number of extensions: 3930399
Number of successful extensions: 26376
Number of sequences better than 10.0: 30
Number of HSP's better than 10.0 without gapping: 187
Number of HSP's successfully gapped in prelim test: 329
Number of HSP's that attempted gapping in prelim test: 9812
Number of HSP's gapped (non-prelim): 5735
length of query: 1396
length of database: 18,247,518
effective HSP length: 115
effective length of query: 1281
effective length of database: 13,892,928
effective search space: 17796840768
effective search space used: 17796840768
T: 11
A: 40
X1: 16 ( 7.4 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 41 (21.8 bits)
S2: 68 (30.8 bits)
Search results were obtained with NCBI BLAST and RefSeq entries.
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Guide to the Human Genome
Copyright © 2010 by Stewart Scherer. All rights reserved.