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Search of human proteins with 46249376
BLASTP 2.2.11 [Jun-05-2005]
Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer,
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997),
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs", Nucleic Acids Res. 25:3389-3402.
Query= gi|46249376 protein phosphatase 1, catalytic subunit, beta
isoform 1 [Homo sapiens]
(327 letters)
Database: hs.faa
37,866 sequences; 18,247,518 total letters
Searching..................................................done
Score E
Sequences producing significant alignments: (bits) Value
gi|46249376 protein phosphatase 1, catalytic subunit, beta isofo... 683 0.0
gi|4506005 protein phosphatase 1, catalytic subunit, beta isofor... 683 0.0
gi|4506003 protein phosphatase 1, catalytic subunit, alpha isofo... 605 e-173
gi|56790945 protein phosphatase 1, catalytic subunit, alpha isof... 596 e-171
gi|4506007 protein phosphatase 1, catalytic subunit, gamma isofo... 592 e-169
gi|45827798 protein phosphatase 1, catalytic subunit, alpha isof... 513 e-145
gi|57222565 protein phosphatase 2, catalytic subunit, beta isofo... 290 2e-78
gi|4758952 protein phosphatase 2, catalytic subunit, beta isofor... 290 2e-78
gi|4506027 protein phosphatase 4, catalytic subunit [Homo sapiens] 288 3e-78
gi|4506017 protein phosphatase 2, catalytic subunit, alpha isofo... 287 8e-78
gi|4506029 protein phosphatase 6, catalytic subunit isoform b [H... 258 4e-69
gi|183603929 protein phosphatase 6, catalytic subunit isoform a ... 256 3e-68
gi|183603931 protein phosphatase 6, catalytic subunit isoform c ... 224 1e-58
gi|194688147 protein phosphatase 3, catalytic subunit, alpha iso... 221 9e-58
gi|6715568 protein phosphatase 3, catalytic subunit, alpha isofo... 221 9e-58
gi|194688149 protein phosphatase 3, catalytic subunit, alpha iso... 220 1e-57
gi|21361290 protein phosphatase 3, catalytic subunit, gamma [Hom... 216 2e-56
gi|215272354 protein phosphatase 3, catalytic subunit, beta isof... 216 2e-56
gi|215272352 protein phosphatase 3, catalytic subunit, beta isof... 216 2e-56
gi|11036640 protein phosphatase 3, catalytic subunit, beta isofo... 216 2e-56
gi|5453958 protein phosphatase 5, catalytic subunit [Homo sapiens] 207 1e-53
gi|23312374 protein phosphatase with EF hand calcium-binding dom... 146 3e-35
gi|23312380 protein phosphatase with EF hand calcium-binding dom... 135 5e-32
gi|239752750 PREDICTED: similar to protein phosphatase 2, cataly... 119 5e-27
gi|239747318 PREDICTED: similar to protein phosphatase 2, cataly... 118 6e-27
gi|239741140 PREDICTED: similar to protein phosphatase 2, cataly... 118 6e-27
gi|23312386 serine/threonine protein phosphatase with EF-hand mo... 117 1e-26
gi|23312378 protein phosphatase with EF hand calcium-binding dom... 102 5e-22
gi|190610008 zinc finger protein 317 [Homo sapiens] 30 3.8
>gi|46249376 protein phosphatase 1, catalytic subunit, beta isoform
1 [Homo sapiens]
Length = 327
Score = 683 bits (1763), Expect = 0.0
Identities = 327/327 (100%), Positives = 327/327 (100%)
Query: 1 MADGELNVDSLITRLLEVRGCRPGKIVQMTEAEVRGLCIKSREIFLSQPILLELEAPLKI 60
MADGELNVDSLITRLLEVRGCRPGKIVQMTEAEVRGLCIKSREIFLSQPILLELEAPLKI
Sbjct: 1 MADGELNVDSLITRLLEVRGCRPGKIVQMTEAEVRGLCIKSREIFLSQPILLELEAPLKI 60
Query: 61 CGDIHGQYTDLLRLFEYGGFPPEANYLFLGDYVDRGKQSLETICLLLAYKIKYPENFFLL 120
CGDIHGQYTDLLRLFEYGGFPPEANYLFLGDYVDRGKQSLETICLLLAYKIKYPENFFLL
Sbjct: 61 CGDIHGQYTDLLRLFEYGGFPPEANYLFLGDYVDRGKQSLETICLLLAYKIKYPENFFLL 120
Query: 121 RGNHECASINRIYGFYDECKRRFNIKLWKTFTDCFNCLPIAAIVDEKIFCCHGGLSPDLQ 180
RGNHECASINRIYGFYDECKRRFNIKLWKTFTDCFNCLPIAAIVDEKIFCCHGGLSPDLQ
Sbjct: 121 RGNHECASINRIYGFYDECKRRFNIKLWKTFTDCFNCLPIAAIVDEKIFCCHGGLSPDLQ 180
Query: 181 SMEQIRRIMRPTDVPDTGLLCDLLWSDPDKDVQGWGENDRGVSFTFGADVVSKFLNRHDL 240
SMEQIRRIMRPTDVPDTGLLCDLLWSDPDKDVQGWGENDRGVSFTFGADVVSKFLNRHDL
Sbjct: 181 SMEQIRRIMRPTDVPDTGLLCDLLWSDPDKDVQGWGENDRGVSFTFGADVVSKFLNRHDL 240
Query: 241 DLICRAHQVVEDGYEFFAKRQLVTLFSAPNYCGEFDNAGGMMSVDETLMCSFQILKPSEK 300
DLICRAHQVVEDGYEFFAKRQLVTLFSAPNYCGEFDNAGGMMSVDETLMCSFQILKPSEK
Sbjct: 241 DLICRAHQVVEDGYEFFAKRQLVTLFSAPNYCGEFDNAGGMMSVDETLMCSFQILKPSEK 300
Query: 301 KAKYQYGGLNSGRPVTPPRTANPPKKR 327
KAKYQYGGLNSGRPVTPPRTANPPKKR
Sbjct: 301 KAKYQYGGLNSGRPVTPPRTANPPKKR 327
>gi|4506005 protein phosphatase 1, catalytic subunit, beta isoform 1
[Homo sapiens]
Length = 327
Score = 683 bits (1763), Expect = 0.0
Identities = 327/327 (100%), Positives = 327/327 (100%)
Query: 1 MADGELNVDSLITRLLEVRGCRPGKIVQMTEAEVRGLCIKSREIFLSQPILLELEAPLKI 60
MADGELNVDSLITRLLEVRGCRPGKIVQMTEAEVRGLCIKSREIFLSQPILLELEAPLKI
Sbjct: 1 MADGELNVDSLITRLLEVRGCRPGKIVQMTEAEVRGLCIKSREIFLSQPILLELEAPLKI 60
Query: 61 CGDIHGQYTDLLRLFEYGGFPPEANYLFLGDYVDRGKQSLETICLLLAYKIKYPENFFLL 120
CGDIHGQYTDLLRLFEYGGFPPEANYLFLGDYVDRGKQSLETICLLLAYKIKYPENFFLL
Sbjct: 61 CGDIHGQYTDLLRLFEYGGFPPEANYLFLGDYVDRGKQSLETICLLLAYKIKYPENFFLL 120
Query: 121 RGNHECASINRIYGFYDECKRRFNIKLWKTFTDCFNCLPIAAIVDEKIFCCHGGLSPDLQ 180
RGNHECASINRIYGFYDECKRRFNIKLWKTFTDCFNCLPIAAIVDEKIFCCHGGLSPDLQ
Sbjct: 121 RGNHECASINRIYGFYDECKRRFNIKLWKTFTDCFNCLPIAAIVDEKIFCCHGGLSPDLQ 180
Query: 181 SMEQIRRIMRPTDVPDTGLLCDLLWSDPDKDVQGWGENDRGVSFTFGADVVSKFLNRHDL 240
SMEQIRRIMRPTDVPDTGLLCDLLWSDPDKDVQGWGENDRGVSFTFGADVVSKFLNRHDL
Sbjct: 181 SMEQIRRIMRPTDVPDTGLLCDLLWSDPDKDVQGWGENDRGVSFTFGADVVSKFLNRHDL 240
Query: 241 DLICRAHQVVEDGYEFFAKRQLVTLFSAPNYCGEFDNAGGMMSVDETLMCSFQILKPSEK 300
DLICRAHQVVEDGYEFFAKRQLVTLFSAPNYCGEFDNAGGMMSVDETLMCSFQILKPSEK
Sbjct: 241 DLICRAHQVVEDGYEFFAKRQLVTLFSAPNYCGEFDNAGGMMSVDETLMCSFQILKPSEK 300
Query: 301 KAKYQYGGLNSGRPVTPPRTANPPKKR 327
KAKYQYGGLNSGRPVTPPRTANPPKKR
Sbjct: 301 KAKYQYGGLNSGRPVTPPRTANPPKKR 327
>gi|4506003 protein phosphatase 1, catalytic subunit, alpha isoform
1 [Homo sapiens]
Length = 330
Score = 605 bits (1559), Expect = e-173
Identities = 293/330 (88%), Positives = 311/330 (94%), Gaps = 4/330 (1%)
Query: 1 MADGE-LNVDSLITRLLEVRGCRPGKIVQMTEAEVRGLCIKSREIFLSQPILLELEAPLK 59
M+D E LN+DS+I RLLEV+G RPGK VQ+TE E+RGLC+KSREIFLSQPILLELEAPLK
Sbjct: 1 MSDSEKLNLDSIIGRLLEVQGSRPGKNVQLTENEIRGLCLKSREIFLSQPILLELEAPLK 60
Query: 60 ICGDIHGQYTDLLRLFEYGGFPPEANYLFLGDYVDRGKQSLETICLLLAYKIKYPENFFL 119
ICGDIHGQY DLLRLFEYGGFPPE+NYLFLGDYVDRGKQSLETICLLLAYKIKYPENFFL
Sbjct: 61 ICGDIHGQYYDLLRLFEYGGFPPESNYLFLGDYVDRGKQSLETICLLLAYKIKYPENFFL 120
Query: 120 LRGNHECASINRIYGFYDECKRRFNIKLWKTFTDCFNCLPIAAIVDEKIFCCHGGLSPDL 179
LRGNHECASINRIYGFYDECKRR+NIKLWKTFTDCFNCLPIAAIVDEKIFCCHGGLSPDL
Sbjct: 121 LRGNHECASINRIYGFYDECKRRYNIKLWKTFTDCFNCLPIAAIVDEKIFCCHGGLSPDL 180
Query: 180 QSMEQIRRIMRPTDVPDTGLLCDLLWSDPDKDVQGWGENDRGVSFTFGADVVSKFLNRHD 239
QSMEQIRRIMRPTDVPD GLLCDLLWSDPDKDVQGWGENDRGVSFTFGA+VV+KFL++HD
Sbjct: 181 QSMEQIRRIMRPTDVPDQGLLCDLLWSDPDKDVQGWGENDRGVSFTFGAEVVAKFLHKHD 240
Query: 240 LDLICRAHQVVEDGYEFFAKRQLVTLFSAPNYCGEFDNAGGMMSVDETLMCSFQILKPSE 299
LDLICRAHQVVEDGYEFFAKRQLVTLFSAPNYCGEFDNAG MMSVDETLMCSFQILKP++
Sbjct: 241 LDLICRAHQVVEDGYEFFAKRQLVTLFSAPNYCGEFDNAGAMMSVDETLMCSFQILKPAD 300
Query: 300 K-KAKY-QYGGLN-SGRPVTPPRTANPPKK 326
K K KY Q+ GLN GRP+TPPR + KK
Sbjct: 301 KNKGKYGQFSGLNPGGRPITPPRNSAKAKK 330
>gi|56790945 protein phosphatase 1, catalytic subunit, alpha isoform
3 [Homo sapiens]
Length = 341
Score = 596 bits (1537), Expect = e-171
Identities = 293/341 (85%), Positives = 311/341 (91%), Gaps = 15/341 (4%)
Query: 1 MADGE-LNVDSLITRLLE-----------VRGCRPGKIVQMTEAEVRGLCIKSREIFLSQ 48
M+D E LN+DS+I RLLE V+G RPGK VQ+TE E+RGLC+KSREIFLSQ
Sbjct: 1 MSDSEKLNLDSIIGRLLEGSRVLTPHCAPVQGSRPGKNVQLTENEIRGLCLKSREIFLSQ 60
Query: 49 PILLELEAPLKICGDIHGQYTDLLRLFEYGGFPPEANYLFLGDYVDRGKQSLETICLLLA 108
PILLELEAPLKICGDIHGQY DLLRLFEYGGFPPE+NYLFLGDYVDRGKQSLETICLLLA
Sbjct: 61 PILLELEAPLKICGDIHGQYYDLLRLFEYGGFPPESNYLFLGDYVDRGKQSLETICLLLA 120
Query: 109 YKIKYPENFFLLRGNHECASINRIYGFYDECKRRFNIKLWKTFTDCFNCLPIAAIVDEKI 168
YKIKYPENFFLLRGNHECASINRIYGFYDECKRR+NIKLWKTFTDCFNCLPIAAIVDEKI
Sbjct: 121 YKIKYPENFFLLRGNHECASINRIYGFYDECKRRYNIKLWKTFTDCFNCLPIAAIVDEKI 180
Query: 169 FCCHGGLSPDLQSMEQIRRIMRPTDVPDTGLLCDLLWSDPDKDVQGWGENDRGVSFTFGA 228
FCCHGGLSPDLQSMEQIRRIMRPTDVPD GLLCDLLWSDPDKDVQGWGENDRGVSFTFGA
Sbjct: 181 FCCHGGLSPDLQSMEQIRRIMRPTDVPDQGLLCDLLWSDPDKDVQGWGENDRGVSFTFGA 240
Query: 229 DVVSKFLNRHDLDLICRAHQVVEDGYEFFAKRQLVTLFSAPNYCGEFDNAGGMMSVDETL 288
+VV+KFL++HDLDLICRAHQVVEDGYEFFAKRQLVTLFSAPNYCGEFDNAG MMSVDETL
Sbjct: 241 EVVAKFLHKHDLDLICRAHQVVEDGYEFFAKRQLVTLFSAPNYCGEFDNAGAMMSVDETL 300
Query: 289 MCSFQILKPSEK-KAKY-QYGGLN-SGRPVTPPRTANPPKK 326
MCSFQILKP++K K KY Q+ GLN GRP+TPPR + KK
Sbjct: 301 MCSFQILKPADKNKGKYGQFSGLNPGGRPITPPRNSAKAKK 341
>gi|4506007 protein phosphatase 1, catalytic subunit, gamma isoform
[Homo sapiens]
Length = 323
Score = 592 bits (1525), Expect = e-169
Identities = 285/320 (89%), Positives = 300/320 (93%), Gaps = 7/320 (2%)
Query: 1 MAD-GELNVDSLITRLLEVRGCRPGKIVQMTEAEVRGLCIKSREIFLSQPILLELEAPLK 59
MAD +LN+DS+I RLLEVRG +PGK VQ+ E E+RGLC+KSREIFLSQPILLELEAPLK
Sbjct: 1 MADLDKLNIDSIIQRLLEVRGSKPGKNVQLQENEIRGLCLKSREIFLSQPILLELEAPLK 60
Query: 60 ICGDIHGQYTDLLRLFEYGGFPPEANYLFLGDYVDRGKQSLETICLLLAYKIKYPENFFL 119
ICGDIHGQY DLLRLFEYGGFPPE+NYLFLGDYVDRGKQSLETICLLLAYKIKYPENFFL
Sbjct: 61 ICGDIHGQYYDLLRLFEYGGFPPESNYLFLGDYVDRGKQSLETICLLLAYKIKYPENFFL 120
Query: 120 LRGNHECASINRIYGFYDECKRRFNIKLWKTFTDCFNCLPIAAIVDEKIFCCHGGLSPDL 179
LRGNHECASINRIYGFYDECKRR+NIKLWKTFTDCFNCLPIAAIVDEKIFCCHGGLSPDL
Sbjct: 121 LRGNHECASINRIYGFYDECKRRYNIKLWKTFTDCFNCLPIAAIVDEKIFCCHGGLSPDL 180
Query: 180 QSMEQIRRIMRPTDVPDTGLLCDLLWSDPDKDVQGWGENDRGVSFTFGADVVSKFLNRHD 239
QSMEQIRRIMRPTDVPD GLLCDLLWSDPDKDV GWGENDRGVSFTFGA+VV+KFL++HD
Sbjct: 181 QSMEQIRRIMRPTDVPDQGLLCDLLWSDPDKDVLGWGENDRGVSFTFGAEVVAKFLHKHD 240
Query: 240 LDLICRAHQVVEDGYEFFAKRQLVTLFSAPNYCGEFDNAGGMMSVDETLMCSFQILKPSE 299
LDLICRAHQVVEDGYEFFAKRQLVTLFSAPNYCGEFDNAG MMSVDETLMCSFQILKP+E
Sbjct: 241 LDLICRAHQVVEDGYEFFAKRQLVTLFSAPNYCGEFDNAGAMMSVDETLMCSFQILKPAE 300
Query: 300 KKAKYQYGGLNSGRPVTPPR 319
KK N+ RPVTPPR
Sbjct: 301 KKKP------NATRPVTPPR 314
>gi|45827798 protein phosphatase 1, catalytic subunit, alpha isoform
2 [Homo sapiens]
Length = 286
Score = 513 bits (1320), Expect = e-145
Identities = 244/268 (91%), Positives = 255/268 (95%), Gaps = 3/268 (1%)
Query: 62 GDIHGQYTDLLRLFEYGGFPPEANYLFLGDYVDRGKQSLETICLLLAYKIKYPENFFLLR 121
GDIHGQY DLLRLFEYGGFPPE+NYLFLGDYVDRGKQSLETICLLLAYKIKYPENFFLLR
Sbjct: 19 GDIHGQYYDLLRLFEYGGFPPESNYLFLGDYVDRGKQSLETICLLLAYKIKYPENFFLLR 78
Query: 122 GNHECASINRIYGFYDECKRRFNIKLWKTFTDCFNCLPIAAIVDEKIFCCHGGLSPDLQS 181
GNHECASINRIYGFYDECKRR+NIKLWKTFTDCFNCLPIAAIVDEKIFCCHGGLSPDLQS
Sbjct: 79 GNHECASINRIYGFYDECKRRYNIKLWKTFTDCFNCLPIAAIVDEKIFCCHGGLSPDLQS 138
Query: 182 MEQIRRIMRPTDVPDTGLLCDLLWSDPDKDVQGWGENDRGVSFTFGADVVSKFLNRHDLD 241
MEQIRRIMRPTDVPD GLLCDLLWSDPDKDVQGWGENDRGVSFTFGA+VV+KFL++HDLD
Sbjct: 139 MEQIRRIMRPTDVPDQGLLCDLLWSDPDKDVQGWGENDRGVSFTFGAEVVAKFLHKHDLD 198
Query: 242 LICRAHQVVEDGYEFFAKRQLVTLFSAPNYCGEFDNAGGMMSVDETLMCSFQILKPSEK- 300
LICRAHQVVEDGYEFFAKRQLVTLFSAPNYCGEFDNAG MMSVDETLMCSFQILKP++K
Sbjct: 199 LICRAHQVVEDGYEFFAKRQLVTLFSAPNYCGEFDNAGAMMSVDETLMCSFQILKPADKN 258
Query: 301 KAKY-QYGGLN-SGRPVTPPRTANPPKK 326
K KY Q+ GLN GRP+TPPR + KK
Sbjct: 259 KGKYGQFSGLNPGGRPITPPRNSAKAKK 286
>gi|57222565 protein phosphatase 2, catalytic subunit, beta isoform
[Homo sapiens]
Length = 309
Score = 290 bits (741), Expect = 2e-78
Identities = 134/277 (48%), Positives = 188/277 (67%), Gaps = 2/277 (0%)
Query: 28 QMTEAEVRGLCIKSREIFLSQPILLELEAPLKICGDIHGQYTDLLRLFEYGGFPPEANYL 87
Q+ E +VR LC K++EI + + E+ P+ +CGD+HGQ+ DL+ LF GG P+ NYL
Sbjct: 22 QLNENQVRTLCEKAKEILTKESNVQEVRCPVTVCGDVHGQFHDLMELFRIGGKSPDTNYL 81
Query: 88 FLGDYVDRGKQSLETICLLLAYKIKYPENFFLLRGNHECASINRIYGFYDECKRRF-NIK 146
F+GDYVDRG S+ET+ LL+A K++YPE +LRGNHE I ++YGFYDEC R++ N
Sbjct: 82 FMGDYVDRGYYSVETVTLLVALKVRYPERITILRGNHESRQITQVYGFYDECLRKYGNAN 141
Query: 147 LWKTFTDCFNCLPIAAIVDEKIFCCHGGLSPDLQSMEQIRRIMRPTDVPDTGLLCDLLWS 206
+WK FTD F+ LP+ A+VD +IFC HGGLSP + +++ IR + R +VP G +CDLLWS
Sbjct: 142 VWKYFTDLFDYLPLTALVDGQIFCLHGGLSPSIDTLDHIRALDRLQEVPHEGPMCDLLWS 201
Query: 207 DPDKDVQGWGENDRGVSFTFGADVVSKFLNRHDLDLICRAHQVVEDGYEFFAKRQLVTLF 266
DPD D GWG + RG +TFG D+ F + + L L+ RAHQ+V +GY + R +VT+F
Sbjct: 202 DPD-DRGGWGISPRGAGYTFGQDISETFNHANGLTLVSRAHQLVMEGYNWCHDRNVVTIF 260
Query: 267 SAPNYCGEFDNAGGMMSVDETLMCSFQILKPSEKKAK 303
SAPNYC N +M +D+TL SF P+ ++ +
Sbjct: 261 SAPNYCYRCGNQAAIMELDDTLKYSFLQFDPAPRRGE 297
>gi|4758952 protein phosphatase 2, catalytic subunit, beta isoform
[Homo sapiens]
Length = 309
Score = 290 bits (741), Expect = 2e-78
Identities = 134/277 (48%), Positives = 188/277 (67%), Gaps = 2/277 (0%)
Query: 28 QMTEAEVRGLCIKSREIFLSQPILLELEAPLKICGDIHGQYTDLLRLFEYGGFPPEANYL 87
Q+ E +VR LC K++EI + + E+ P+ +CGD+HGQ+ DL+ LF GG P+ NYL
Sbjct: 22 QLNENQVRTLCEKAKEILTKESNVQEVRCPVTVCGDVHGQFHDLMELFRIGGKSPDTNYL 81
Query: 88 FLGDYVDRGKQSLETICLLLAYKIKYPENFFLLRGNHECASINRIYGFYDECKRRF-NIK 146
F+GDYVDRG S+ET+ LL+A K++YPE +LRGNHE I ++YGFYDEC R++ N
Sbjct: 82 FMGDYVDRGYYSVETVTLLVALKVRYPERITILRGNHESRQITQVYGFYDECLRKYGNAN 141
Query: 147 LWKTFTDCFNCLPIAAIVDEKIFCCHGGLSPDLQSMEQIRRIMRPTDVPDTGLLCDLLWS 206
+WK FTD F+ LP+ A+VD +IFC HGGLSP + +++ IR + R +VP G +CDLLWS
Sbjct: 142 VWKYFTDLFDYLPLTALVDGQIFCLHGGLSPSIDTLDHIRALDRLQEVPHEGPMCDLLWS 201
Query: 207 DPDKDVQGWGENDRGVSFTFGADVVSKFLNRHDLDLICRAHQVVEDGYEFFAKRQLVTLF 266
DPD D GWG + RG +TFG D+ F + + L L+ RAHQ+V +GY + R +VT+F
Sbjct: 202 DPD-DRGGWGISPRGAGYTFGQDISETFNHANGLTLVSRAHQLVMEGYNWCHDRNVVTIF 260
Query: 267 SAPNYCGEFDNAGGMMSVDETLMCSFQILKPSEKKAK 303
SAPNYC N +M +D+TL SF P+ ++ +
Sbjct: 261 SAPNYCYRCGNQAAIMELDDTLKYSFLQFDPAPRRGE 297
>gi|4506027 protein phosphatase 4, catalytic subunit [Homo sapiens]
Length = 307
Score = 288 bits (738), Expect = 3e-78
Identities = 134/286 (46%), Positives = 199/286 (69%), Gaps = 6/286 (2%)
Query: 31 EAEVRGLCIKSREIFLSQPILLELEAPLKICGDIHGQYTDLLRLFEYGGFPPEANYLFLG 90
E+EV+ LC K+REI + + + +++P+ +CGDIHGQ+ DL LF GG PE NYLF+G
Sbjct: 22 ESEVKALCAKAREILVEESNVQRVDSPVTVCGDIHGQFYDLKELFRVGGDVPETNYLFMG 81
Query: 91 DYVDRGKQSLETICLLLAYKIKYPENFFLLRGNHECASINRIYGFYDECKRRF-NIKLWK 149
D+VDRG S+ET LLLA K++YP+ L+RGNHE I ++YGFYDEC R++ ++ +W+
Sbjct: 82 DFVDRGFYSVETFLLLLALKVRYPDRITLIRGNHESRQITQVYGFYDECLRKYGSVTVWR 141
Query: 150 TFTDCFNCLPIAAIVDEKIFCCHGGLSPDLQSMEQIRRIMRPTDVPDTGLLCDLLWSDPD 209
T+ F+ L ++AI+D KIFC HGGLSP +Q+++QIR I R +VP G +CDLLWSDP+
Sbjct: 142 YCTEIFDYLSLSAIIDGKIFCVHGGLSPSIQTLDQIRTIDRKQEVPHDGPMCDLLWSDPE 201
Query: 210 KDVQGWGENDRGVSFTFGADVVSKFLNRHDLDLICRAHQVVEDGYEFFAKRQLVTLFSAP 269
D GWG + RG + FG+DVV++F +D+D+ICRAHQ+V +GY++ ++T++SAP
Sbjct: 202 -DTTGWGVSPRGAGYLFGSDVVAQFNAANDIDMICRAHQLVMEGYKWHFNETVLTVWSAP 260
Query: 270 NYCGEFDNAGGMMSVDETLMCSFQILKPSEKKAKYQYGGLNSGRPV 315
NYC N ++ +DE L F I + + ++ + G+ S +PV
Sbjct: 261 NYCYRCGNVAAILELDEHLQKDFIIFEAAPQETR----GIPSKKPV 302
>gi|4506017 protein phosphatase 2, catalytic subunit, alpha isoform
[Homo sapiens]
Length = 309
Score = 287 bits (735), Expect = 8e-78
Identities = 132/277 (47%), Positives = 189/277 (68%), Gaps = 2/277 (0%)
Query: 28 QMTEAEVRGLCIKSREIFLSQPILLELEAPLKICGDIHGQYTDLLRLFEYGGFPPEANYL 87
Q++E++V+ LC K++EI + + E+ P+ +CGD+HGQ+ DL+ LF GG P+ NYL
Sbjct: 22 QLSESQVKSLCEKAKEILTKESNVQEVRCPVTVCGDVHGQFHDLMELFRIGGKSPDTNYL 81
Query: 88 FLGDYVDRGKQSLETICLLLAYKIKYPENFFLLRGNHECASINRIYGFYDECKRRF-NIK 146
F+GDYVDRG S+ET+ LL+A K++Y E +LRGNHE I ++YGFYDEC R++ N
Sbjct: 82 FMGDYVDRGYYSVETVTLLVALKVRYRERITILRGNHESRQITQVYGFYDECLRKYGNAN 141
Query: 147 LWKTFTDCFNCLPIAAIVDEKIFCCHGGLSPDLQSMEQIRRIMRPTDVPDTGLLCDLLWS 206
+WK FTD F+ LP+ A+VD +IFC HGGLSP + +++ IR + R +VP G +CDLLWS
Sbjct: 142 VWKYFTDLFDYLPLTALVDGQIFCLHGGLSPSIDTLDHIRALDRLQEVPHEGPMCDLLWS 201
Query: 207 DPDKDVQGWGENDRGVSFTFGADVVSKFLNRHDLDLICRAHQVVEDGYEFFAKRQLVTLF 266
DPD D GWG + RG +TFG D+ F + + L L+ RAHQ+V +GY + R +VT+F
Sbjct: 202 DPD-DRGGWGISPRGAGYTFGQDISETFNHANGLTLVSRAHQLVMEGYNWCHDRNVVTIF 260
Query: 267 SAPNYCGEFDNAGGMMSVDETLMCSFQILKPSEKKAK 303
SAPNYC N +M +D+TL SF P+ ++ +
Sbjct: 261 SAPNYCYRCGNQAAIMELDDTLKYSFLQFDPAPRRGE 297
>gi|4506029 protein phosphatase 6, catalytic subunit isoform b [Homo
sapiens]
Length = 305
Score = 258 bits (660), Expect = 4e-69
Identities = 125/296 (42%), Positives = 182/296 (61%), Gaps = 13/296 (4%)
Query: 29 MTEAEVRGLCIKSREIFLSQPILLELEAPLKICGDIHGQYTDLLRLFEYGGFPPEANYLF 88
+ E +++ LC ++ L + + + P+ +CGDIHGQ+ DL LF GG P+ NY+F
Sbjct: 19 LPENDLKRLCDYVCDLLLEESNVQPVSTPVTVCGDIHGQFYDLCELFRTGGQVPDTNYIF 78
Query: 89 LGDYVDRGKQSLETICLLLAYKIKYPENFFLLRGNHECASINRIYGFYDECKRRF-NIKL 147
+GD+VDRG SLET LLA K K+P+ LLRGNHE I ++YGFYDEC+ ++ N
Sbjct: 79 MGDFVDRGYYSLETFTYLLALKAKWPDRITLLRGNHESRQITQVYGFYDECQTKYGNANA 138
Query: 148 WKTFTDCFNCLPIAAIVDEKIFCCHGGLSPDLQSMEQIRRIMRPTDVPDTGLLCDLLWSD 207
W+ T F+ L +AA++DE+I C HGGLSPD+++++QIR I R ++P G CDL+WSD
Sbjct: 139 WRYCTKVFDMLTVAALIDEQILCVHGGLSPDIKTLDQIRTIERNQEIPHKGAFCDLVWSD 198
Query: 208 PDKDVQGWGENDRGVSFTFGADVVSKFLNRHDLDLICRAHQVVEDGYEFFAKRQLVTLFS 267
P+ DV W + RG + FGA V ++F++ ++L LICRAHQ+V +GY+F +LVT++S
Sbjct: 199 PE-DVDTWAISPRGAGWLFGAKVTNEFVHINNLKLICRAHQLVHEGYKFMFDEKLVTVWS 257
Query: 268 APNYCGEFDNAGGMMSVDETLMCSFQILKPSEKKAKYQYGGLNSGRPVTPPRTANP 323
APNYC N + S + K + + + V PPRT P
Sbjct: 258 APNYCYRCGN-----------IASIMVFKDVNTREPKLFRAVPDSERVIPPRTTTP 302
>gi|183603929 protein phosphatase 6, catalytic subunit isoform a
[Homo sapiens]
Length = 342
Score = 256 bits (653), Expect = 3e-68
Identities = 124/288 (43%), Positives = 177/288 (61%), Gaps = 13/288 (4%)
Query: 37 LCIKSREIFLSQPILLELEAPLKICGDIHGQYTDLLRLFEYGGFPPEANYLFLGDYVDRG 96
LC ++ L + + + P+ +CGDIHGQ+ DL LF GG P+ NY+F+GD+VDRG
Sbjct: 64 LCDYVCDLLLEESNVQPVSTPVTVCGDIHGQFYDLCELFRTGGQVPDTNYIFMGDFVDRG 123
Query: 97 KQSLETICLLLAYKIKYPENFFLLRGNHECASINRIYGFYDECKRRF-NIKLWKTFTDCF 155
SLET LLA K K+P+ LLRGNHE I ++YGFYDEC+ ++ N W+ T F
Sbjct: 124 YYSLETFTYLLALKAKWPDRITLLRGNHESRQITQVYGFYDECQTKYGNANAWRYCTKVF 183
Query: 156 NCLPIAAIVDEKIFCCHGGLSPDLQSMEQIRRIMRPTDVPDTGLLCDLLWSDPDKDVQGW 215
+ L +AA++DE+I C HGGLSPD+++++QIR I R ++P G CDL+WSDP+ DV W
Sbjct: 184 DMLTVAALIDEQILCVHGGLSPDIKTLDQIRTIERNQEIPHKGAFCDLVWSDPE-DVDTW 242
Query: 216 GENDRGVSFTFGADVVSKFLNRHDLDLICRAHQVVEDGYEFFAKRQLVTLFSAPNYCGEF 275
+ RG + FGA V ++F++ ++L LICRAHQ+V +GY+F +LVT++SAPNYC
Sbjct: 243 AISPRGAGWLFGAKVTNEFVHINNLKLICRAHQLVHEGYKFMFDEKLVTVWSAPNYCYRC 302
Query: 276 DNAGGMMSVDETLMCSFQILKPSEKKAKYQYGGLNSGRPVTPPRTANP 323
N + S + K + + + V PPRT P
Sbjct: 303 GN-----------IASIMVFKDVNTREPKLFRAVPDSERVIPPRTTTP 339
>gi|183603931 protein phosphatase 6, catalytic subunit isoform c
[Homo sapiens]
Length = 283
Score = 224 bits (570), Expect = 1e-58
Identities = 115/296 (38%), Positives = 168/296 (56%), Gaps = 35/296 (11%)
Query: 29 MTEAEVRGLCIKSREIFLSQPILLELEAPLKICGDIHGQYTDLLRLFEYGGFPPEANYLF 88
+ E +++ LC ++ L + + + P+ +CGDIHGQ
Sbjct: 19 LPENDLKRLCDYVCDLLLEESNVQPVSTPVTVCGDIHGQ--------------------- 57
Query: 89 LGDYVDRGKQSLETICLLLAYKIKYPENFFLLRGNHECASINRIYGFYDECKRRF-NIKL 147
GD+VDRG SLET LLA K K+P+ LLRGNHE I ++YGFYDEC+ ++ N
Sbjct: 58 -GDFVDRGYYSLETFTYLLALKAKWPDRITLLRGNHESRQITQVYGFYDECQTKYGNANA 116
Query: 148 WKTFTDCFNCLPIAAIVDEKIFCCHGGLSPDLQSMEQIRRIMRPTDVPDTGLLCDLLWSD 207
W+ T F+ L +AA++DE+I C HGGLSPD+++++QIR I R ++P G CDL+WSD
Sbjct: 117 WRYCTKVFDMLTVAALIDEQILCVHGGLSPDIKTLDQIRTIERNQEIPHKGAFCDLVWSD 176
Query: 208 PDKDVQGWGENDRGVSFTFGADVVSKFLNRHDLDLICRAHQVVEDGYEFFAKRQLVTLFS 267
P+ DV W + RG + FGA V ++F++ ++L LICRAHQ+V +GY+F +LVT++S
Sbjct: 177 PE-DVDTWAISPRGAGWLFGAKVTNEFVHINNLKLICRAHQLVHEGYKFMFDEKLVTVWS 235
Query: 268 APNYCGEFDNAGGMMSVDETLMCSFQILKPSEKKAKYQYGGLNSGRPVTPPRTANP 323
APNYC N + S + K + + + V PPRT P
Sbjct: 236 APNYCYRCGN-----------IASIMVFKDVNTREPKLFRAVPDSERVIPPRTTTP 280
>gi|194688147 protein phosphatase 3, catalytic subunit, alpha
isoform isoform 2 [Homo sapiens]
Length = 511
Score = 221 bits (562), Expect = 9e-58
Identities = 113/300 (37%), Positives = 176/300 (58%), Gaps = 21/300 (7%)
Query: 3 DGELNVDSLITRLLEVRGCRPGKIVQMTEAEVRGLCIKSREIFLSQPILLELEAPLKICG 62
DG+ VD L L+ K ++ E+ + + I + LL+++AP+ +CG
Sbjct: 38 DGKPRVDILKAHLM--------KEGRLEESVALRIITEGASILRQEKNLLDIDAPVTVCG 89
Query: 63 DIHGQYTDLLRLFEYGGFPPEANYLFLGDYVDRGKQSLETICLLLAYKIKYPENFFLLRG 122
DIHGQ+ DL++LFE GG P YLFLGDYVDRG S+E + L A KI YP+ FLLRG
Sbjct: 90 DIHGQFFDLMKLFEVGGSPANTRYLFLGDYVDRGYFSIECVLYLWALKILYPKTLFLLRG 149
Query: 123 NHECASINRIYGFYDECKRRFNIKLWKTFTDCFNCLPIAAIVDEKIFCCHGGLSPDLQSM 182
NHEC + + F ECK +++ +++ D F+CLP+AA+++++ C HGGLSP++ ++
Sbjct: 150 NHECRHLTEYFTFKQECKIKYSERVYDACMDAFDCLPLAALMNQQFLCVHGGLSPEINTL 209
Query: 183 EQIRRIMRPTDVPDTGLLCDLLWSDP------DKDVQGWGEND-RGVSFTFGADVVSKFL 235
+ IR++ R + P G +CD+LWSDP +K + + N RG S+ + V +FL
Sbjct: 210 DDIRKLDRFKEPPAYGPMCDILWSDPLEDFGNEKTQEHFTHNTVRGCSYFYSYPAVCEFL 269
Query: 236 NRHDLDLICRAHQVVEDGYEFFAKRQ------LVTLFSAPNYCGEFDNAGGMMSVDETLM 289
++L I RAH+ + GY + K Q L+T+FSAPNY ++N ++ + +M
Sbjct: 270 QHNNLLSILRAHEAQDAGYRMYRKSQTTGFPSLITIFSAPNYLDVYNNKAAVLKYENNVM 329
>gi|6715568 protein phosphatase 3, catalytic subunit, alpha isoform
isoform 1 [Homo sapiens]
Length = 521
Score = 221 bits (562), Expect = 9e-58
Identities = 113/300 (37%), Positives = 176/300 (58%), Gaps = 21/300 (7%)
Query: 3 DGELNVDSLITRLLEVRGCRPGKIVQMTEAEVRGLCIKSREIFLSQPILLELEAPLKICG 62
DG+ VD L L+ K ++ E+ + + I + LL+++AP+ +CG
Sbjct: 38 DGKPRVDILKAHLM--------KEGRLEESVALRIITEGASILRQEKNLLDIDAPVTVCG 89
Query: 63 DIHGQYTDLLRLFEYGGFPPEANYLFLGDYVDRGKQSLETICLLLAYKIKYPENFFLLRG 122
DIHGQ+ DL++LFE GG P YLFLGDYVDRG S+E + L A KI YP+ FLLRG
Sbjct: 90 DIHGQFFDLMKLFEVGGSPANTRYLFLGDYVDRGYFSIECVLYLWALKILYPKTLFLLRG 149
Query: 123 NHECASINRIYGFYDECKRRFNIKLWKTFTDCFNCLPIAAIVDEKIFCCHGGLSPDLQSM 182
NHEC + + F ECK +++ +++ D F+CLP+AA+++++ C HGGLSP++ ++
Sbjct: 150 NHECRHLTEYFTFKQECKIKYSERVYDACMDAFDCLPLAALMNQQFLCVHGGLSPEINTL 209
Query: 183 EQIRRIMRPTDVPDTGLLCDLLWSDP------DKDVQGWGEND-RGVSFTFGADVVSKFL 235
+ IR++ R + P G +CD+LWSDP +K + + N RG S+ + V +FL
Sbjct: 210 DDIRKLDRFKEPPAYGPMCDILWSDPLEDFGNEKTQEHFTHNTVRGCSYFYSYPAVCEFL 269
Query: 236 NRHDLDLICRAHQVVEDGYEFFAKRQ------LVTLFSAPNYCGEFDNAGGMMSVDETLM 289
++L I RAH+ + GY + K Q L+T+FSAPNY ++N ++ + +M
Sbjct: 270 QHNNLLSILRAHEAQDAGYRMYRKSQTTGFPSLITIFSAPNYLDVYNNKAAVLKYENNVM 329
>gi|194688149 protein phosphatase 3, catalytic subunit, alpha
isoform isoform 3 [Homo sapiens]
Length = 469
Score = 220 bits (561), Expect = 1e-57
Identities = 116/302 (38%), Positives = 177/302 (58%), Gaps = 21/302 (6%)
Query: 3 DGELNVDSLITRLLEVRGCRPGKIVQMTEAEVRGLCIKSREIFLSQPILLELEAPLKICG 62
DG+ VD L L+ K ++ E+ + + I + LL+++AP+ +CG
Sbjct: 38 DGKPRVDILKAHLM--------KEGRLEESVALRIITEGASILRQEKNLLDIDAPVTVCG 89
Query: 63 DIHGQYTDLLRLFEYGGFPPEANYLFLGDYVDRGKQSLETICLLLAYKIKYPENFFLLRG 122
DIHGQ+ DL++LFE GG P YLFLGDYVDRG S+E + L A KI YP+ FLLRG
Sbjct: 90 DIHGQFFDLMKLFEVGGSPANTRYLFLGDYVDRGYFSIECVLYLWALKILYPKTLFLLRG 149
Query: 123 NHECASINRIYGFYDECKRRFNIKLWKTFTDCFNCLPIAAIVDEKIFCCHGGLSPDLQSM 182
NHEC + + F ECK +++ +++ D F+CLP+AA+++++ C HGGLSP++ ++
Sbjct: 150 NHECRHLTEYFTFKQECKIKYSERVYDACMDAFDCLPLAALMNQQFLCVHGGLSPEINTL 209
Query: 183 EQIRRIMRPTDVPDTGLLCDLLWSDP------DKDVQGWGEND-RGVSFTFGADVVSKFL 235
+ IR++ R + P G +CD+LWSDP +K + + N RG S+ + V +FL
Sbjct: 210 DDIRKLDRFKEPPAYGPMCDILWSDPLEDFGNEKTQEHFTHNTVRGCSYFYSYPAVCEFL 269
Query: 236 NRHDLDLICRAHQVVEDGYEFFAKRQ------LVTLFSAPNYCGEFDNAGGMMSVDETLM 289
++L I RAH+ + GY + K Q L+T+FSAPNY ++N M V+ +
Sbjct: 270 QHNNLLSILRAHEAQDAGYRMYRKSQTTGFPSLITIFSAPNYLDVYNNKVTEMLVNVLNI 329
Query: 290 CS 291
CS
Sbjct: 330 CS 331
>gi|21361290 protein phosphatase 3, catalytic subunit, gamma [Homo
sapiens]
Length = 512
Score = 216 bits (551), Expect = 2e-56
Identities = 102/259 (39%), Positives = 163/259 (62%), Gaps = 13/259 (5%)
Query: 44 IFLSQPILLELEAPLKICGDIHGQYTDLLRLFEYGGFPPEANYLFLGDYVDRGKQSLETI 103
I + ++E++AP+ +CGDIHGQ+ DL++LFE GG P YLFLGDYVDRG S+E +
Sbjct: 67 ILRQEKTMIEVDAPITVCGDIHGQFFDLMKLFEVGGSPSNTRYLFLGDYVDRGYFSIECV 126
Query: 104 CLLLAYKIKYPENFFLLRGNHECASINRIYGFYDECKRRFNIKLWKTFTDCFNCLPIAAI 163
L + KI +P+ FLLRGNHEC + + F EC+ +++ +++ + F+CLP+AA+
Sbjct: 127 LYLWSLKINHPKTLFLLRGNHECRHLTDYFTFKQECRIKYSEQVYDACMETFDCLPLAAL 186
Query: 164 VDEKIFCCHGGLSPDLQSMEQIRRIMRPTDVPDTGLLCDLLWSDPDKD------VQGWGE 217
++++ C HGG+SP++ S++ IR++ R T+ P G +CDLLWSDP +D ++ +
Sbjct: 187 LNQQFLCVHGGMSPEITSLDDIRKLDRFTEPPAFGPVCDLLWSDPSEDYGNEKTLEHYTH 246
Query: 218 ND-RGVSFTFGADVVSKFLNRHDLDLICRAHQVVEDGYEFFAKRQ------LVTLFSAPN 270
N RG S+ + V +FL ++L I RAH+ + GY + K Q L+T+FSAPN
Sbjct: 247 NTVRGCSYFYSYPAVCEFLQNNNLLSIIRAHEAQDAGYRMYRKSQATGFPSLITIFSAPN 306
Query: 271 YCGEFDNAGGMMSVDETLM 289
Y ++N ++ + +M
Sbjct: 307 YLDVYNNKAAVLKYENNVM 325
>gi|215272354 protein phosphatase 3, catalytic subunit, beta isoform
c [Homo sapiens]
Length = 515
Score = 216 bits (550), Expect = 2e-56
Identities = 103/259 (39%), Positives = 157/259 (60%), Gaps = 13/259 (5%)
Query: 44 IFLSQPILLELEAPLKICGDIHGQYTDLLRLFEYGGFPPEANYLFLGDYVDRGKQSLETI 103
I + ++E+EAP+ +CGDIHGQ+ DL++LFE GG P YLFLGDYVDRG S+E +
Sbjct: 80 ILRREKTMIEVEAPITVCGDIHGQFFDLMKLFEVGGSPANTRYLFLGDYVDRGYFSIECV 139
Query: 104 CLLLAYKIKYPENFFLLRGNHECASINRIYGFYDECKRRFNIKLWKTFTDCFNCLPIAAI 163
L KI YP FLLRGNHEC + + F ECK +++ ++++ + F+ LP+AA+
Sbjct: 140 LYLWVLKILYPSTLFLLRGNHECRHLTEYFTFKQECKIKYSERVYEACMEAFDSLPLAAL 199
Query: 164 VDEKIFCCHGGLSPDLQSMEQIRRIMRPTDVPDTGLLCDLLWSDPDKDVQGWGEND---- 219
++++ C HGGLSP++ +++ IRR+ R + P G +CDLLWSDP +D +
Sbjct: 200 LNQQFLCVHGGLSPEIHTLDDIRRLDRFKEPPAFGPMCDLLWSDPSEDFGNEKSQEHFSH 259
Query: 220 ---RGVSFTFGADVVSKFLNRHDLDLICRAHQVVEDGYEFFAKRQ------LVTLFSAPN 270
RG S+ + V +FL ++L I RAH+ + GY + K Q L+T+FSAPN
Sbjct: 260 NTVRGCSYFYNYPAVCEFLQNNNLLSIIRAHEAQDAGYRMYRKSQTTGFPSLITIFSAPN 319
Query: 271 YCGEFDNAGGMMSVDETLM 289
Y ++N ++ + +M
Sbjct: 320 YLDVYNNKAAVLKYENNVM 338
>gi|215272352 protein phosphatase 3, catalytic subunit, beta isoform
a [Homo sapiens]
Length = 525
Score = 216 bits (550), Expect = 2e-56
Identities = 103/259 (39%), Positives = 157/259 (60%), Gaps = 13/259 (5%)
Query: 44 IFLSQPILLELEAPLKICGDIHGQYTDLLRLFEYGGFPPEANYLFLGDYVDRGKQSLETI 103
I + ++E+EAP+ +CGDIHGQ+ DL++LFE GG P YLFLGDYVDRG S+E +
Sbjct: 80 ILRREKTMIEVEAPITVCGDIHGQFFDLMKLFEVGGSPANTRYLFLGDYVDRGYFSIECV 139
Query: 104 CLLLAYKIKYPENFFLLRGNHECASINRIYGFYDECKRRFNIKLWKTFTDCFNCLPIAAI 163
L KI YP FLLRGNHEC + + F ECK +++ ++++ + F+ LP+AA+
Sbjct: 140 LYLWVLKILYPSTLFLLRGNHECRHLTEYFTFKQECKIKYSERVYEACMEAFDSLPLAAL 199
Query: 164 VDEKIFCCHGGLSPDLQSMEQIRRIMRPTDVPDTGLLCDLLWSDPDKDVQGWGEND---- 219
++++ C HGGLSP++ +++ IRR+ R + P G +CDLLWSDP +D +
Sbjct: 200 LNQQFLCVHGGLSPEIHTLDDIRRLDRFKEPPAFGPMCDLLWSDPSEDFGNEKSQEHFSH 259
Query: 220 ---RGVSFTFGADVVSKFLNRHDLDLICRAHQVVEDGYEFFAKRQ------LVTLFSAPN 270
RG S+ + V +FL ++L I RAH+ + GY + K Q L+T+FSAPN
Sbjct: 260 NTVRGCSYFYNYPAVCEFLQNNNLLSIIRAHEAQDAGYRMYRKSQTTGFPSLITIFSAPN 319
Query: 271 YCGEFDNAGGMMSVDETLM 289
Y ++N ++ + +M
Sbjct: 320 YLDVYNNKAAVLKYENNVM 338
>gi|11036640 protein phosphatase 3, catalytic subunit, beta isoform
b [Homo sapiens]
Length = 524
Score = 216 bits (550), Expect = 2e-56
Identities = 103/259 (39%), Positives = 157/259 (60%), Gaps = 13/259 (5%)
Query: 44 IFLSQPILLELEAPLKICGDIHGQYTDLLRLFEYGGFPPEANYLFLGDYVDRGKQSLETI 103
I + ++E+EAP+ +CGDIHGQ+ DL++LFE GG P YLFLGDYVDRG S+E +
Sbjct: 80 ILRREKTMIEVEAPITVCGDIHGQFFDLMKLFEVGGSPANTRYLFLGDYVDRGYFSIECV 139
Query: 104 CLLLAYKIKYPENFFLLRGNHECASINRIYGFYDECKRRFNIKLWKTFTDCFNCLPIAAI 163
L KI YP FLLRGNHEC + + F ECK +++ ++++ + F+ LP+AA+
Sbjct: 140 LYLWVLKILYPSTLFLLRGNHECRHLTEYFTFKQECKIKYSERVYEACMEAFDSLPLAAL 199
Query: 164 VDEKIFCCHGGLSPDLQSMEQIRRIMRPTDVPDTGLLCDLLWSDPDKDVQGWGEND---- 219
++++ C HGGLSP++ +++ IRR+ R + P G +CDLLWSDP +D +
Sbjct: 200 LNQQFLCVHGGLSPEIHTLDDIRRLDRFKEPPAFGPMCDLLWSDPSEDFGNEKSQEHFSH 259
Query: 220 ---RGVSFTFGADVVSKFLNRHDLDLICRAHQVVEDGYEFFAKRQ------LVTLFSAPN 270
RG S+ + V +FL ++L I RAH+ + GY + K Q L+T+FSAPN
Sbjct: 260 NTVRGCSYFYNYPAVCEFLQNNNLLSIIRAHEAQDAGYRMYRKSQTTGFPSLITIFSAPN 319
Query: 271 YCGEFDNAGGMMSVDETLM 289
Y ++N ++ + +M
Sbjct: 320 YLDVYNNKAAVLKYENNVM 338
>gi|5453958 protein phosphatase 5, catalytic subunit [Homo sapiens]
Length = 499
Score = 207 bits (526), Expect = 1e-53
Identities = 112/261 (42%), Positives = 158/261 (60%), Gaps = 11/261 (4%)
Query: 19 RGCRPGKIVQMTEAEVRGLCIKSREIFLSQPILLELEAPLKICGDIHGQYTDLLRLFEYG 78
R C +VQ+ E + S+ L + L E E + +CGD HGQ+ DLL +FE
Sbjct: 206 RKCAYQILVQVKE-------VLSKLSTLVETTLKETEK-ITVCGDTHGQFYDLLNIFELN 257
Query: 79 GFPPEAN-YLFLGDYVDRGKQSLETICLLLAYKIKYPENFFLLRGNHECASINRIYGFYD 137
G P E N Y+F GD+VDRG S+E I L +K+ YP++F LLRGNHE ++N+IYGF
Sbjct: 258 GLPSETNPYIFNGDFVDRGSFSVEVILTLFGFKLLYPDHFHLLRGNHETDNMNQIYGFEG 317
Query: 138 ECKRRFNIKLWKTFTDCFNCLPIAAIVDEKIFCCHGGL-SPDLQSMEQIRRIMRPTDVPD 196
E K ++ ++++ F++ F LP+A ++ K+ HGGL S D +++ IR+I R PD
Sbjct: 318 EVKAKYTAQMYELFSEVFEWLPLAQCINGKVLIMHGGLFSEDGVTLDDIRKIERNRQPPD 377
Query: 197 TGLLCDLLWSDPDKDVQGWGENDRGVSFTFGADVVSKFLNRHDLDLICRAHQVVEDGYEF 256
+G +CDLLWSDP G + RGVS FG DV FL ++LD I R+H+V +GYE
Sbjct: 378 SGPMCDLLWSDPQPQ-NGRSISKRGVSCQFGPDVTKAFLEENNLDYIIRSHEVKAEGYEV 436
Query: 257 FAKRQLVTLFSAPNYCGEFDN 277
+ VT+FSAPNYC + N
Sbjct: 437 AHGGRCVTVFSAPNYCDQMGN 457
>gi|23312374 protein phosphatase with EF hand calcium-binding domain
1 isoform 1b [Homo sapiens]
Length = 625
Score = 146 bits (368), Expect = 3e-35
Identities = 87/244 (35%), Positives = 128/244 (52%), Gaps = 19/244 (7%)
Query: 60 ICGDIHGQYTDLLRLFEYGGFPPEAN-YLFLGDYVDRGKQSLETICLLLAYKIKYPENFF 118
ICGD+HG+ DL +F G P E N Y+F GD+VDRGK S+E + +L + YP +
Sbjct: 169 ICGDLHGKLDDLFLIFYKNGLPSERNPYVFNGDFVDRGKNSIEILMILCVSFLVYPNDLH 228
Query: 119 LLRGNHECASINRIYGFYDECKRRFNI---KLWKTFTDCFNCLPIAAIVDEKIFCCHGGL 175
L RGNHE +N YGF E ++ + ++ + + + LPI IVD +I HGG+
Sbjct: 229 LNRGNHEDFMMNLRYGFTKEILHKYKLHGKRILQILEEFYAWLPIGTIVDNEILVIHGGI 288
Query: 176 S--PDLQSMEQI-RRIMRPTDVPDT------------GLLCDLLWSDPDKDVQGWGENDR 220
S DL + ++ R M+ +P T + D+LWSDP + R
Sbjct: 289 SETTDLNLLHRVERNKMKSVLIPPTETNRDHDTDSKHNKIIDILWSDPRGKNGCFPNTCR 348
Query: 221 GVSFTFGADVVSKFLNRHDLDLICRAHQVVEDGYEFFAKRQLVTLFSAPNYCGEFDNAGG 280
G FG DV SK LN++ L ++ R+H+ +GYE ++VT+FSA NY E N G
Sbjct: 349 GGGCYFGPDVTSKILNKYQLKMLIRSHECKPEGYEICHDGKVVTIFSASNYYEEGSNRGA 408
Query: 281 MMSV 284
+ +
Sbjct: 409 YIKL 412
>gi|23312380 protein phosphatase with EF hand calcium-binding domain
1 isoform 1 [Homo sapiens]
Length = 653
Score = 135 bits (340), Expect = 5e-32
Identities = 88/272 (32%), Positives = 130/272 (47%), Gaps = 47/272 (17%)
Query: 60 ICGDIHGQYTDLLRLFEYGGFPPEAN-YLFLGDYVDRGKQSLETICLLLAYKIKYPENFF 118
ICGD+HG+ DL +F G P E N Y+F GD+VDRGK S+E + +L + YP +
Sbjct: 169 ICGDLHGKLDDLFLIFYKNGLPSERNPYVFNGDFVDRGKNSIEILMILCVSFLVYPNDLH 228
Query: 119 LLRGNHECASINRIYGFYDECKRRFNI---KLWKTFTDCFNCLPIAAIVDEKIFCCHGGL 175
L RGNHE +N YGF E ++ + ++ + + + LPI IVD +I HGG+
Sbjct: 229 LNRGNHEDFMMNLRYGFTKEILHKYKLHGKRILQILEEFYAWLPIGTIVDNEILVIHGGI 288
Query: 176 S--PDLQSMEQIRR------IMRPTDV----------------------------PDTGL 199
S DL + ++ R ++ PT+ P L
Sbjct: 289 SETTDLNLLHRVERNKMKSVLIPPTETNRDHDTDSKHNKVGVTFNAHGRIKTNGSPTEHL 348
Query: 200 -------LCDLLWSDPDKDVQGWGENDRGVSFTFGADVVSKFLNRHDLDLICRAHQVVED 252
+ D+LWSDP + RG FG DV SK LN++ L ++ R+H+ +
Sbjct: 349 TEHEWEQIIDILWSDPRGKNGCFPNTCRGGGCYFGPDVTSKILNKYQLKMLIRSHECKPE 408
Query: 253 GYEFFAKRQLVTLFSAPNYCGEFDNAGGMMSV 284
GYE ++VT+FSA NY E N G + +
Sbjct: 409 GYEICHDGKVVTIFSASNYYEEGSNRGAYIKL 440
>gi|239752750 PREDICTED: similar to protein phosphatase 2, catalytic
subunit, alpha [Homo sapiens]
Length = 384
Score = 119 bits (297), Expect = 5e-27
Identities = 83/278 (29%), Positives = 121/278 (43%), Gaps = 58/278 (20%)
Query: 4 GELNVDSLITRLLEVRGCRPGKIVQMTEAEVRGLCIKSREIFLSQPILLELEAPLKICGD 63
G V S LL + + + +V+ LC +++EI + E+ P+ + GD
Sbjct: 147 GSRGVGSSSASLLPTPAPKAAALDGLGSRKVKSLCKEAKEILTEESNAQEVWCPVTVSGD 206
Query: 64 IHGQYTDLLRLFEYGGFPPEANYLFLGDYVDRGKQSLETICLLLAYKIKYPENFFLLRGN 123
HGQ GDY+DRG S+E + LLLA K+ Y E +L N
Sbjct: 207 KHGQ----------------------GDYIDRGYYSIEIVMLLLAVKVSYHECVTILPRN 244
Query: 124 HECASINRIYGFYDECKRRFNIKLWKTFTDCFNCLPIAAIVDEKIFCCHGGLSPDLQSME 183
HE I ++Y Y+EC R+ A D ++FC HGGLSP + ++
Sbjct: 245 HESRQITQVYHSYEECLRKHG----------------NANGDGQLFCLHGGLSPSVDTLH 288
Query: 184 QIRRIMRPTDVPDTGLLCDLLWSDPDKDVQGWGENDRGVSFTFGADVVSKFLNRHDLDLI 243
IR + +P G + DLL+SDPD D F + L L+
Sbjct: 289 HIRTLNCLQKIPHEGPMGDLLYSDPDDH-----------------DTPETFNHASGLRLV 331
Query: 244 CRAHQVVEDGYEFFAKRQLVTLFSAPNYCGEFDNAGGM 281
RAHQ+V G+ + +V +FS PNYC + GGM
Sbjct: 332 SRAHQLVMVGHNWCHDWNVVAIFSTPNYC---YHCGGM 366
>gi|239747318 PREDICTED: similar to protein phosphatase 2, catalytic
subunit, alpha [Homo sapiens]
Length = 254
Score = 118 bits (296), Expect = 6e-27
Identities = 80/269 (29%), Positives = 117/269 (43%), Gaps = 55/269 (20%)
Query: 4 GELNVDSLITRLLEVRGCRPGKIVQMTEAEVRGLCIKSREIFLSQPILLELEAPLKICGD 63
G V S LL + + + +V+ LC +++EI + E+ P+ + GD
Sbjct: 26 GSRGVGSSSASLLPTPAPKAAALDGLGSRKVKSLCKEAKEILTEESNAQEVWCPVTVSGD 85
Query: 64 IHGQYTDLLRLFEYGGFPPEANYLFLGDYVDRGKQSLETICLLLAYKIKYPENFFLLRGN 123
HGQ GDY+DRG S+E + LLLA K+ Y E +L N
Sbjct: 86 KHGQ----------------------GDYIDRGYYSIEIVMLLLAVKVSYHECVTILPRN 123
Query: 124 HECASINRIYGFYDECKRRFNIKLWKTFTDCFNCLPIAAIVDEKIFCCHGGLSPDLQSME 183
HE I ++Y Y+EC R+ A D ++FC HGGLSP + ++
Sbjct: 124 HESRQITQVYHSYEECLRKHG----------------NANGDGQLFCLHGGLSPSVDTLH 167
Query: 184 QIRRIMRPTDVPDTGLLCDLLWSDPDKDVQGWGENDRGVSFTFGADVVSKFLNRHDLDLI 243
IR + +P G + DLL+SDPD D F + L L+
Sbjct: 168 HIRTLNCLQKIPHEGPMGDLLYSDPDDH-----------------DTPETFNHASGLRLV 210
Query: 244 CRAHQVVEDGYEFFAKRQLVTLFSAPNYC 272
RAHQ+V G+ + +V +FS PNYC
Sbjct: 211 SRAHQLVMVGHNWCHDWNVVAIFSTPNYC 239
>gi|239741140 PREDICTED: similar to protein phosphatase 2, catalytic
subunit, alpha [Homo sapiens]
Length = 254
Score = 118 bits (296), Expect = 6e-27
Identities = 80/269 (29%), Positives = 117/269 (43%), Gaps = 55/269 (20%)
Query: 4 GELNVDSLITRLLEVRGCRPGKIVQMTEAEVRGLCIKSREIFLSQPILLELEAPLKICGD 63
G V S LL + + + +V+ LC +++EI + E+ P+ + GD
Sbjct: 26 GSRGVGSSSASLLPTPAPKAAALDGLGSRKVKSLCKEAKEILTEESNAQEVWCPVTVSGD 85
Query: 64 IHGQYTDLLRLFEYGGFPPEANYLFLGDYVDRGKQSLETICLLLAYKIKYPENFFLLRGN 123
HGQ GDY+DRG S+E + LLLA K+ Y E +L N
Sbjct: 86 KHGQ----------------------GDYIDRGYYSIEIVMLLLAVKVSYHECVTILPRN 123
Query: 124 HECASINRIYGFYDECKRRFNIKLWKTFTDCFNCLPIAAIVDEKIFCCHGGLSPDLQSME 183
HE I ++Y Y+EC R+ A D ++FC HGGLSP + ++
Sbjct: 124 HESRQITQVYHSYEECLRKHG----------------NANGDGQLFCLHGGLSPSVDTLH 167
Query: 184 QIRRIMRPTDVPDTGLLCDLLWSDPDKDVQGWGENDRGVSFTFGADVVSKFLNRHDLDLI 243
IR + +P G + DLL+SDPD D F + L L+
Sbjct: 168 HIRTLNCLQKIPHEGPMGDLLYSDPDDH-----------------DTPETFNHASGLRLV 210
Query: 244 CRAHQVVEDGYEFFAKRQLVTLFSAPNYC 272
RAHQ+V G+ + +V +FS PNYC
Sbjct: 211 SRAHQLVMVGHNWCHDWNVVAIFSTPNYC 239
>gi|23312386 serine/threonine protein phosphatase with EF-hand
motifs 2 [Homo sapiens]
Length = 753
Score = 117 bits (293), Expect = 1e-26
Identities = 57/136 (41%), Positives = 87/136 (63%), Gaps = 6/136 (4%)
Query: 58 LKICGDIHGQYTDLLRLFEYGGFP-PEANYLFLGDYVDRGKQSLETICLLLAYKIKYPEN 116
+ +CGD+HGQ DL+ +F G P PE +Y+F GD+VDRGK S+E + +L A+ + YP+
Sbjct: 174 ITVCGDLHGQLDDLIFIFYKNGLPSPERSYVFNGDFVDRGKDSVEILMILFAFMLVYPKE 233
Query: 117 FFLLRGNHECASINRIYGFYDECKRRFNI---KLWKTFTDCFNCLPIAAIVDEKIFCCHG 173
F L RGNHE +N YGF E ++ + ++ +T D F LP+A ++DEK+ HG
Sbjct: 234 FHLNRGNHEDHMVNLRYGFTKEVMNKYKVHGKEILRTLQDVFCWLPLATLIDEKVLILHG 293
Query: 174 GLS--PDLQSMEQIRR 187
G+S DL+ +++I R
Sbjct: 294 GVSDITDLELLDKIER 309
Score = 58.9 bits (141), Expect = 6e-09
Identities = 29/87 (33%), Positives = 45/87 (51%)
Query: 202 DLLWSDPDKDVQGWGENDRGVSFTFGADVVSKFLNRHDLDLICRAHQVVEDGYEFFAKRQ 261
D+LWSDP RG FG DV + L ++++ + R+H+ +GYEF R+
Sbjct: 443 DILWSDPMAQEGCKANTIRGGGCYFGPDVTQQLLQKYNMQFLIRSHECKPEGYEFCHNRK 502
Query: 262 LVTLFSAPNYCGEFDNAGGMMSVDETL 288
++T+FSA NY N G + + L
Sbjct: 503 VLTIFSASNYYEVGSNRGAYVKLGPAL 529
>gi|23312378 protein phosphatase with EF hand calcium-binding domain
1 isoform 3 [Homo sapiens]
Length = 591
Score = 102 bits (254), Expect = 5e-22
Identities = 74/237 (31%), Positives = 112/237 (47%), Gaps = 39/237 (16%)
Query: 60 ICGDIHGQYTDLLRLFEYGGFPPEAN-YLFLGDYVDRGKQSLETICLLLAYKIKYPENFF 118
ICGD+HG+ DL +F G P E N Y+F GD+VDRGK S+E + +L + YP +
Sbjct: 169 ICGDLHGKLDDLFLIFYKNGLPSERNPYVFNGDFVDRGKNSIEILMILCVSFLVYPNDLH 228
Query: 119 LLRGNHECASINRIYGFYDECKRRFNI---KLWKTFTDCFNCLPIAAIVDEKIFCCHGGL 175
L RGNHE +N YGF E ++ + ++ + + + LPI IVD +I HGG+
Sbjct: 229 LNRGNHEDFMMNLRYGFTKEILHKYKLHGKRILQILEEFYAWLPIGTIVDNEILVIHGGI 288
Query: 176 S--PDLQSMEQI-RRIMRPTDVPDTGLLCDLLWSDPDKDVQGWGENDRGVSFTFGADV-- 230
S DL + ++ R M+ +P T ++ D D N GV+F +
Sbjct: 289 SETTDLNLLHRVERNKMKSVLIPPTE-------TNRDHDTDS-KHNKVGVTFNAHGRIKT 340
Query: 231 ---VSKFLNRHDLDLICRAHQVVEDGYEFFAKRQLVTLFSAPNYCGEFDNAGGMMSV 284
++ L H+ + Q+VT+FSA NY E N G + +
Sbjct: 341 NGSPTEHLTEHEWE-------------------QVVTIFSASNYYEEGSNRGAYIKL 378
>gi|190610008 zinc finger protein 317 [Homo sapiens]
Length = 595
Score = 29.6 bits (65), Expect = 3.8
Identities = 22/96 (22%), Positives = 41/96 (42%), Gaps = 12/96 (12%)
Query: 124 HECASINRIYGFYDECKRRFNIKLWKTFTDCFNC-----------LPIAAIVDEKIF-CC 171
+ECA+ +++G Y +R ++ L K +C C + + EK + C
Sbjct: 474 YECAACGKVFGDYLSRRRHMSVHLVKKRVECRQCGKAFRNQSTLKTHMRSHTGEKPYECD 533
Query: 172 HGGLSPDLQSMEQIRRIMRPTDVPDTGLLCDLLWSD 207
H G + + S + R + + P L+C +SD
Sbjct: 534 HCGKAFSIGSNLNVHRRIHTGEKPYECLVCGKAFSD 569
Database: hs.faa
Posted date: Aug 4, 2009 4:42 PM
Number of letters in database: 18,247,518
Number of sequences in database: 37,866
Lambda K H
0.324 0.143 0.451
Gapped
Lambda K H
0.267 0.0410 0.140
Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Hits to DB: 13,904,596
Number of Sequences: 37866
Number of extensions: 634501
Number of successful extensions: 1047
Number of sequences better than 10.0: 29
Number of HSP's better than 10.0 without gapping: 28
Number of HSP's successfully gapped in prelim test: 1
Number of HSP's that attempted gapping in prelim test: 958
Number of HSP's gapped (non-prelim): 32
length of query: 327
length of database: 18,247,518
effective HSP length: 103
effective length of query: 224
effective length of database: 14,347,320
effective search space: 3213799680
effective search space used: 3213799680
T: 11
A: 40
X1: 15 ( 7.0 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 41 (22.0 bits)
S2: 62 (28.5 bits)
Search results were obtained with NCBI BLAST and RefSeq entries.
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Guide to the Human Genome
Copyright © 2010 by Stewart Scherer. All rights reserved.