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Search of human proteins with 13128980
BLASTP 2.2.11 [Jun-05-2005]
Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer,
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997),
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs", Nucleic Acids Res. 25:3389-3402.
Query= gi|13128980 proline rich 14 [Homo sapiens]
(585 letters)
Database: hs.faa
37,866 sequences; 18,247,518 total letters
Searching..................................................done
Score E
Sequences producing significant alignments: (bits) Value
gi|13128980 proline rich 14 [Homo sapiens] 1204 0.0
gi|209969819 hypothetical protein LOC253143 [Homo sapiens] 146 5e-35
gi|239746149 PREDICTED: hypothetical protein LOC80164 [Homo sapi... 80 7e-15
gi|239757130 PREDICTED: hypothetical protein FLJ22184 [Homo sapi... 77 3e-14
gi|239751637 PREDICTED: hypothetical protein FLJ22184 [Homo sapi... 74 5e-13
gi|148762969 myeloid/lymphoid or mixed-lineage leukemia 2 [Homo ... 72 1e-12
gi|47132519 Ras association and pleckstrin homology domains 1 is... 70 4e-12
gi|239754327 PREDICTED: chromosome 6 open reading frame 132 [Hom... 65 2e-10
gi|239748855 PREDICTED: chromosome 6 open reading frame 132 [Hom... 65 2e-10
gi|239742884 PREDICTED: hypothetical protein LOC647024 [Homo sap... 65 2e-10
gi|150170670 piccolo isoform 2 [Homo sapiens] 65 2e-10
gi|150378539 piccolo isoform 1 [Homo sapiens] 65 2e-10
gi|189181724 proteoglycan 4 isoform D [Homo sapiens] 64 5e-10
gi|189181722 proteoglycan 4 isoform C [Homo sapiens] 64 5e-10
gi|189181720 proteoglycan 4 isoform B [Homo sapiens] 64 5e-10
gi|67190163 proteoglycan 4 isoform A [Homo sapiens] 64 5e-10
gi|7662046 myeloid/lymphoid or mixed-lineage leukemia 4 [Homo sa... 62 1e-09
gi|116284398 WAS/WASL interacting protein family, member 1 [Homo... 62 1e-09
gi|38373695 WAS/WASL interacting protein family, member 1 [Homo ... 62 1e-09
gi|224451135 splicing factor, arginine/serine-rich 15 isoform 3 ... 62 1e-09
gi|239752594 PREDICTED: hypothetical protein, partial [Homo sapi... 62 2e-09
gi|91718902 myeloid/lymphoid or mixed-lineage leukemia 3 [Homo s... 61 3e-09
gi|122937496 WAS/WASL interacting protein family, member 3 [Homo... 61 3e-09
gi|150417989 cyclin K isoform 1 [Homo sapiens] 61 3e-09
gi|116284392 mucin 2 precursor [Homo sapiens] 60 6e-09
gi|122937251 lysine (K)-specific demethylase 6B [Homo sapiens] 60 6e-09
gi|19718731 bromodomain-containing protein 4 isoform long [Homo ... 58 2e-08
gi|163914392 glioma tumor suppressor candidate region gene 1 [Ho... 57 5e-08
gi|68161504 Wiskott-Aldrich syndrome protein family member 1 [Ho... 56 8e-08
gi|68161502 Wiskott-Aldrich syndrome protein family member 1 [Ho... 56 8e-08
>gi|13128980 proline rich 14 [Homo sapiens]
Length = 585
Score = 1204 bits (3115), Expect = 0.0
Identities = 585/585 (100%), Positives = 585/585 (100%)
Query: 1 MDLPGDSSPPGQPRLCRQPLTRALWGARSPKRPRLQLPGAPSPLEKASRRVLAVVLEDVM 60
MDLPGDSSPPGQPRLCRQPLTRALWGARSPKRPRLQLPGAPSPLEKASRRVLAVVLEDVM
Sbjct: 1 MDLPGDSSPPGQPRLCRQPLTRALWGARSPKRPRLQLPGAPSPLEKASRRVLAVVLEDVM 60
Query: 61 AVHMVPVVPSKQTSIPQHHSYHQDPVHRQPPASPPRQAGWSSQARPPDPLCLCREPLSRI 120
AVHMVPVVPSKQTSIPQHHSYHQDPVHRQPPASPPRQAGWSSQARPPDPLCLCREPLSRI
Sbjct: 61 AVHMVPVVPSKQTSIPQHHSYHQDPVHRQPPASPPRQAGWSSQARPPDPLCLCREPLSRI 120
Query: 121 HRTSSTLRRRSRTTPGPEEGPSQKVDRAPQPTLVVMLEDIASPRPPAEGFIDETPNFIIP 180
HRTSSTLRRRSRTTPGPEEGPSQKVDRAPQPTLVVMLEDIASPRPPAEGFIDETPNFIIP
Sbjct: 121 HRTSSTLRRRSRTTPGPEEGPSQKVDRAPQPTLVVMLEDIASPRPPAEGFIDETPNFIIP 180
Query: 181 AQRAEPMRIVRQPTPPPGDLEPPFQPSALPADPLESPPTAPDPALELPSTPPPSSLLRPR 240
AQRAEPMRIVRQPTPPPGDLEPPFQPSALPADPLESPPTAPDPALELPSTPPPSSLLRPR
Sbjct: 181 AQRAEPMRIVRQPTPPPGDLEPPFQPSALPADPLESPPTAPDPALELPSTPPPSSLLRPR 240
Query: 241 LSPWGLAPLFRSVRSKLESFADIFLTPNKTPQPPPPSPPMKLELKIAISEAEQSGAAEGT 300
LSPWGLAPLFRSVRSKLESFADIFLTPNKTPQPPPPSPPMKLELKIAISEAEQSGAAEGT
Sbjct: 241 LSPWGLAPLFRSVRSKLESFADIFLTPNKTPQPPPPSPPMKLELKIAISEAEQSGAAEGT 300
Query: 301 ASVSPRPPIRQWRTQDHNTPALLPKPSLGRSYSCPDLGPPGPGTCTWPPAPPQPSRPRPR 360
ASVSPRPPIRQWRTQDHNTPALLPKPSLGRSYSCPDLGPPGPGTCTWPPAPPQPSRPRPR
Sbjct: 301 ASVSPRPPIRQWRTQDHNTPALLPKPSLGRSYSCPDLGPPGPGTCTWPPAPPQPSRPRPR 360
Query: 361 RHTVGGGEMARAPPPPRPCLRKEVFPLGGVGASPSLTTSCSSTASTSFSEPAEPRLGSTK 420
RHTVGGGEMARAPPPPRPCLRKEVFPLGGVGASPSLTTSCSSTASTSFSEPAEPRLGSTK
Sbjct: 361 RHTVGGGEMARAPPPPRPCLRKEVFPLGGVGASPSLTTSCSSTASTSFSEPAEPRLGSTK 420
Query: 421 GKEPRASKDQVLSEPETKTMGKVSRFRIRRTPARPQLNLTPMGLPRPIRLNKKEFSLEEI 480
GKEPRASKDQVLSEPETKTMGKVSRFRIRRTPARPQLNLTPMGLPRPIRLNKKEFSLEEI
Sbjct: 421 GKEPRASKDQVLSEPETKTMGKVSRFRIRRTPARPQLNLTPMGLPRPIRLNKKEFSLEEI 480
Query: 481 YTNKNYQSPTTRRTFETIFEEPRERNGTLIFTSSRKLRRAVEFRDSSLPRSRRPSRGVRA 540
YTNKNYQSPTTRRTFETIFEEPRERNGTLIFTSSRKLRRAVEFRDSSLPRSRRPSRGVRA
Sbjct: 481 YTNKNYQSPTTRRTFETIFEEPRERNGTLIFTSSRKLRRAVEFRDSSLPRSRRPSRGVRA 540
Query: 541 AGGRTVPPNVAPSPDVGPLLQQRLEELDALLLEEETVDREQPHWT 585
AGGRTVPPNVAPSPDVGPLLQQRLEELDALLLEEETVDREQPHWT
Sbjct: 541 AGGRTVPPNVAPSPDVGPLLQQRLEELDALLLEEETVDREQPHWT 585
>gi|209969819 hypothetical protein LOC253143 [Homo sapiens]
Length = 2151
Score = 146 bits (369), Expect = 5e-35
Identities = 107/265 (40%), Positives = 130/265 (49%), Gaps = 43/265 (16%)
Query: 341 GPGTCTW-------PPAPPQPSRPRPRRHTV--------------GGGEMARAPPP---- 375
GP C++ P QPS HT+ G R PP
Sbjct: 1892 GPSVCSFEISSLHSPHCKRQPSLGTTSSHTMLPYVPLPGMEATYNTSGSQTRLEPPFPAL 1951
Query: 376 -PRPCLRKEVFPLGGVGASPSLTTSCSSTASTSFSEPAEPRLGSTKGKEP---RASKDQV 431
P+ CL E A L S S E L K P + +Q
Sbjct: 1952 VPKSCLVAE-------SAVSKLLLSASEFQVRGLDE-----LDGVKAACPCPQSSPPEQK 1999
Query: 432 LSEPETKTMGKVSRFRIRRTPARPQLNLTPMGLPRPIRLNKKEFSLEEIYTNKNYQSPTT 491
+EPE K KVS+ RIR+T RP NLTPMGLPRP RL KKEFSLEEIYTNKNY+SP
Sbjct: 2000 EAEPE-KRPKKVSQIRIRKTIPRPDPNLTPMGLPRPKRLKKKEFSLEEIYTNKNYKSPPA 2058
Query: 492 RRTFETIFEEPRERNGTLIFTSSRKLRRAVEFRDSSLPRSRRPSRGVRAAGGRTVPPNVA 551
R ETIFEEP+ERNGTLI S +K +R +EF+D ++PR RR V+ AG T A
Sbjct: 2059 NRCLETIFEEPKERNGTLISISQQKRKRVLEFQDFTVPRKRRARGKVKVAGSFTRAQKAA 2118
Query: 552 -PSPDVGPLLQQRLEELDALLLEEE 575
S ++ LL Q+L EL+ +EE
Sbjct: 2119 VQSRELDALLIQKLMELETFFAKEE 2143
>gi|239746149 PREDICTED: hypothetical protein LOC80164 [Homo
sapiens]
Length = 816
Score = 79.7 bits (195), Expect = 7e-15
Identities = 110/463 (23%), Positives = 159/463 (34%), Gaps = 63/463 (13%)
Query: 17 RQPLTRALWGARSPKRPRLQLPGAPSPLEKASRRVLAVVLED----VMAVHMVPVVPSKQ 72
++P +R+L + +P L P P + + R A + + A+ V P ++
Sbjct: 226 QRPASRSLSSSATP----LSSPARSGPSARGTPRAPAHPSQPKPKGLQALRPPQVTPPRK 281
Query: 73 TSIPQHHSYHQDPVHRQPPASPPRQAGWSSQARPPDP---------LCLCREPLSRIHRT 123
+ P P+ P++PP + S P P L L H
Sbjct: 282 DAAPALGPLSSSPLATPSPSAPPSPSAPPSLQTLPSPPATPPSQATTSLGSPTLQATHSF 341
Query: 124 SSTLRRRSRTTPGPEEGPS---QKVDRAPQPTLVVMLEDIASPRPPAEGFIDETPNFIIP 180
+ TP P+ P+ + P P L +A+P P A + + +
Sbjct: 342 LPSPPLSPLATPPPQAPPALALPPLQAPPSPPASPPLSPLATPSPQAPNAL--AVHLLQA 399
Query: 181 AQRAEPMRIVRQPTPPPGDLEPPFQPSALPADPLESPPTAPDPALELPSTPPPSSLLRPR 240
P V+ P PP PP PSA P P ++PP+ P L++P +PP S + P
Sbjct: 400 PFSPPPSPPVQAPFSPPAS--PPVSPSATP--PSQAPPSLAAPPLQVPPSPPASPPMSPS 455
Query: 241 LSPWGLAPLFRSVRSKLESFADIFLTPNKTPQPPPPSPPMKLELKI-AISEAEQSGAAEG 299
+P AP + P + +PPP +PP + A+ S +
Sbjct: 456 ATPPPQAP------------PPLAAPPLQLAKPPPQAPPALATPPLQALPSPPASFPGQA 503
Query: 300 TASVSPRPPIRQWRTQDHNTPALLPKPSLGRSYSCPDLGPPGPGTCTWPPAPPQPSRPRP 359
S S P+ T P +L P L PP P AP +P P P
Sbjct: 504 PFSPSASLPMSPLATPPPQAPPVLAAPLLQV--------PPSPPASPTLQAPRRPPTPGP 555
Query: 360 RRHTVGGG-EMARAPPPPRPCLRKEVFPLGGVGASPSLTTSCSSTASTSFSEPAEPRLGS 418
G +A AP PP P R L G P L SS ST P E R G
Sbjct: 556 DTSVSGPRLTLALAPGPPPPPSRSPSSTLSG----PDLAGHSSSATST----PEELR-GY 606
Query: 419 TKGKE------PRASKDQVLSEPETKTMGKVSRFRIRRTPARP 455
G E P + P + G R P P
Sbjct: 607 DSGPEGGAAASPPPDAELAACHPAAWSRGPAPPLAFRGAPGAP 649
Score = 70.5 bits (171), Expect = 4e-12
Identities = 99/403 (24%), Positives = 133/403 (33%), Gaps = 38/403 (9%)
Query: 38 PGAPSP-LEKASRRVLAVVLEDVMAVHMVPVVPSKQ-----TSIPQHHSYHQDPVHRQPP 91
PG PSP + + SR V A P P++ +S +H + P R+ P
Sbjct: 160 PGTPSPAMARRSRAAGTEVGLPRPAPSARPRPPTEGPRKSVSSASEHSTTEPSPAARRRP 219
Query: 92 ASPPRQAGWSSQARPPDPLCLCREPLSRIHRTSSTLRRRSRTTPGPEEGPSQKVDRAPQP 151
+ AG Q L PLS R+ + R R P + + + P
Sbjct: 220 S-----AGGGLQRPASRSLSSSATPLSSPARSGPSARGTPRAPAHPSQPKPKGLQALRPP 274
Query: 152 TLVVMLEDIASPRPPAEGFIDETPNFIIPAQRAEPMRIVRQPTPP---PGDL-------- 200
+ +D A P TP+ P + P + P+PP P
Sbjct: 275 QVTPPRKDAAPALGPLSSSPLATPSPSAPPSPSAPPSLQTLPSPPATPPSQATTSLGSPT 334
Query: 201 ---------EPPFQPSALPADPLESPPTAPDPALELPSTPPPSSLLRPRLSPWGLAPLFR 251
PP P A P P ++PP P L+ P +PP S L P +P AP
Sbjct: 335 LQATHSFLPSPPLSPLATP--PPQAPPALALPPLQAPPSPPASPPLSPLATPSPQAPNAL 392
Query: 252 SVRSKLESFADIFLTPNKTPQPPPPSPPMKLELKIAISEAEQSGAAEGTASVSPRPPIRQ 311
+V F+ P + P PP SPP+ S+A S AA V P PP
Sbjct: 393 AVHLLQAPFSPPPSPPVQAPFSPPASPPVS-PSATPPSQAPPSLAAP-PLQVPPSPPASP 450
Query: 312 WRTQDHNTPALLPKPSLGRSYSCPDLGPPGPGTCTWPPAPPQPSRPRPRRHTVGGGEMAR 371
+ P P P P P PP PS P A
Sbjct: 451 PMSPSATPPPQAPPPLAAPPLQLAKPPPQAPPALATPPLQALPSPPASFPGQAPFSPSAS 510
Query: 372 APPPPRPCLRKEVFPLGGVGASPSLTTSCSSTASTSFSEPAEP 414
P P + P V A+P L S AS + P P
Sbjct: 511 LPMSPLATPPPQAPP---VLAAPLLQVPPSPPASPTLQAPRRP 550
Score = 54.3 bits (129), Expect = 3e-07
Identities = 80/310 (25%), Positives = 111/310 (35%), Gaps = 51/310 (16%)
Query: 181 AQRAEPMRIVRQPTPPPGDLEPPFQPSALPADPLESPPTAPDPALELPSTPPPSSLLRPR 240
A RA P R R P G+ PP + ++ P+ SP A + P P R
Sbjct: 74 APRAGPTRTSRPPASGRGERAPPAKNTS--PGPVSSPGRASG-----TTRPGPLGQKGLR 126
Query: 241 LSPWGLAPLFRSVRS-KLESFADIFLTPNKTPQPPPPSPPMKLELKIAISEAEQSGAAEG 299
+S ++ + K + + P P PSP M + A +E G
Sbjct: 127 ISAEETVARGKATEAPKRSALSAGARRDTSGPTPGTPSPAMARRSRAAGTEV---GLPRP 183
Query: 300 TASVSPRPPIRQWR-----TQDHNT----PALLPKPSLG----------RSYSCPDLGPP 340
S PRPP R +H+T PA +PS G S S L P
Sbjct: 184 APSARPRPPTEGPRKSVSSASEHSTTEPSPAARRRPSAGGGLQRPASRSLSSSATPLSSP 243
Query: 341 ---GPGTCTWPPAPPQPSRPRPRRHTVGGGEMARAPPPPRPCLRKEVFPLGGVGASPSLT 397
GP P AP PS+P+P+ G A PP P + LG + +SP T
Sbjct: 244 ARSGPSARGTPRAPAHPSQPKPK------GLQALRPPQVTPPRKDAAPALGPLSSSPLAT 297
Query: 398 TSCSSTASTSFSEPAEPRLGSTKGKEPRASKDQVLSEPETKTMGKVSRFRIRRTPARPQL 457
S S+ S P+ P T P Q + + T+ F P+ P
Sbjct: 298 PSPSAPPS-----PSAPPSLQTLPSPPATPPSQATTSLGSPTLQATHSF----LPSPP-- 346
Query: 458 NLTPMGLPRP 467
L+P+ P P
Sbjct: 347 -LSPLATPPP 355
Score = 52.0 bits (123), Expect = 2e-06
Identities = 106/400 (26%), Positives = 134/400 (33%), Gaps = 101/400 (25%)
Query: 4 PGDSSPPGQPRLCRQPLTRALWGARSPKRPRLQ-----LPGAP-SPLEKASRRVL-AVVL 56
P S+PP L P T S P LQ LP P SPL + A+ L
Sbjct: 304 PSPSAPPSLQTLPSPPATPPSQATTSLGSPTLQATHSFLPSPPLSPLATPPPQAPPALAL 363
Query: 57 EDVMAVHMVPVVP------SKQTSIPQHHSYHQDPVHRQPPASPPRQAGWSSQARPP--- 107
+ A P P + P + H PP SPP QA +S A PP
Sbjct: 364 PPLQAPPSPPASPPLSPLATPSPQAPNALAVHLLQAPFSPPPSPPVQAPFSPPASPPVSP 423
Query: 108 -------DPLCLCREPLSRIHRTSSTLRRRSRTTPGPEEGPSQKVDRAPQPTLVVMLEDI 160
P L PL ++ TP P+ AP P L+ +
Sbjct: 424 SATPPSQAPPSLAAPPLQVPPSPPASPPMSPSATPPPQ---------APPPLAAPPLQ-L 473
Query: 161 ASPRPPAEGFIDETPNFIIPAQRAEPMRIVRQPTPP---PGDLEPPFQPSA-LPADPLES 216
A P P A PA P++ + P+PP PG + PF PSA LP PL +
Sbjct: 474 AKPPPQAP-----------PALATPPLQAL--PSPPASFPG--QAPFSPSASLPMSPLAT 518
Query: 217 PPTAPDPALELP--------------------STP-PPSSLLRPRLSPWGLAPLFRSVRS 255
PP P L P TP P +S+ PRL+ LAP
Sbjct: 519 PPPQAPPVLAAPLLQVPPSPPASPTLQAPRRPPTPGPDTSVSGPRLT-LALAP------- 570
Query: 256 KLESFADIFLTPNKTPQPPPPSPPMKLELKIAISEAEQ----SGAAEGTASVSPRPPIRQ 311
P+++P P + A S E+ EG A+ SP P
Sbjct: 571 ------GPPPPPSRSPSSTLSGPDLAGHSSSATSTPEELRGYDSGPEGGAAASPPP---- 620
Query: 312 WRTQDHNTPALLPKP-SLGRSYSCPDLGPPGPGTCTWPPA 350
D A P S G + G PG WPPA
Sbjct: 621 ----DAELAACHPAAWSRGPAPPLAFRGAPG-APLPWPPA 655
Score = 31.6 bits (70), Expect = 2.1
Identities = 31/122 (25%), Positives = 40/122 (32%), Gaps = 23/122 (18%)
Query: 267 PNKTPQPPPPSPPMKLELKIAISE------AEQSGAAEGTASVSPRPPIRQWRTQDHNTP 320
P +P+PPPP P L + A AE++G G P RT
Sbjct: 29 PPGSPRPPPPVTPAALRVLGAAGAVGRKPLAERAGGIGGATIPESAPRAGPTRTS----- 83
Query: 321 ALLPKPSLGRSYSCPDLGPPGPGTCTWPPAPPQPSRPRP---------RRHTVGGGEMAR 371
P+ GR P PG + P +RP P TV G+
Sbjct: 84 ---RPPASGRGERAPPAKNTSPGPVSSPGRASGTTRPGPLGQKGLRISAEETVARGKATE 140
Query: 372 AP 373
AP
Sbjct: 141 AP 142
Score = 31.2 bits (69), Expect = 2.8
Identities = 61/227 (26%), Positives = 69/227 (30%), Gaps = 62/227 (27%)
Query: 342 PGTCTWPPAPPQPSRPRPRRHTVGGGEMARAPPPPRPCLRKEVFPLGGVGASPSLTTSCS 401
PG T P P PRP PPP P + + G VG P L
Sbjct: 22 PGLLT----PRPPGSPRP-------------PPPVTPAALRVLGAAGAVGRKP-LAERAG 63
Query: 402 STASTSFSEPAEPRLGSTKGKEPRASKDQVLSEPETKTM-GKVSRFRIRRTPARPQLNLT 460
+ E A PR G T+ P AS + P T G VS +P R
Sbjct: 64 GIGGATIPESA-PRAGPTRTSRPPASGRGERAPPAKNTSPGPVS------SPGRAS---- 112
Query: 461 PMGLPRPIRLNKKEFSLEEIYTNKNYQSPTTRRTFETIFEEPRERNGTLIFTSSRKLRRA 520
G RP L +K I E G R A
Sbjct: 113 --GTTRPGPLGQKGL---------------------RISAEETVARGKATEAPKRSALSA 149
Query: 521 VEFRDSSLPRSRRPS----RGVRAAGGRTVPPNVAPS-----PDVGP 558
RD+S P PS R RAAG P APS P GP
Sbjct: 150 GARRDTSGPTPGTPSPAMARRSRAAGTEVGLPRPAPSARPRPPTEGP 196
>gi|239757130 PREDICTED: hypothetical protein FLJ22184 [Homo
sapiens]
Length = 855
Score = 77.4 bits (189), Expect = 3e-14
Identities = 98/377 (25%), Positives = 130/377 (34%), Gaps = 56/377 (14%)
Query: 90 PPASPPRQAGWSSQARPPDPLCLCREPLSRIHRTSSTLRRRSRTTPGPEEGPS---QKVD 146
PPA+PP QA S L L H + TP P+ P+ +
Sbjct: 357 PPATPPSQATTS----------LGSPTLQATHSFLPSPPLSPLATPPPQAPPALALPPLQ 406
Query: 147 RAPQPTLVVMLEDIASPRPPAEGFIDETPNFIIPAQRAEPMRIVRQPTPPPGDLEPPFQP 206
P P L +A+P P A + + + P V+ P PP PP P
Sbjct: 407 APPSPPASPPLSPLATPSPQAPNAL--AVHLLQAPFSPPPSPPVQAPFSPPAS--PPVSP 462
Query: 207 SALPADPLESPPTAPDPALELPSTPPPSSLLRPRLSPWGLAPLFRSVRSKLESFADIFLT 266
SA P P ++PP+ P L++P +PP S + P +P AP +
Sbjct: 463 SATP--PSQAPPSLAAPPLQVPPSPPASPPMSPSATPPPQAP------------PPLAAP 508
Query: 267 PNKTPQPPPPSPPMKLELKI-AISEAEQSGAAEGTASVSPRPPIRQWRTQDHNTPALLPK 325
P + +PPP +PP + A+ S + S S P+ T P +L
Sbjct: 509 PLQLAKPPPQAPPALATPPLQALPSPPASFPGQAPFSPSASLPMSPLATPPPQAPPVLAA 568
Query: 326 PSLGRSYSCPDLGPPGPGTCTWPPAPPQPSRPRPRRHTVGGG-EMARAPPPPRPCLRKEV 384
P L PP P AP +P P P G +A AP PP P R
Sbjct: 569 PLLQV--------PPSPPASPTLQAPRRPPTPGPDTSVSGPRLTLALAPGPPPPPSRSPS 620
Query: 385 FPLGGVGASPSLTTSCSSTASTSFSEPAEPRLGSTKGKE------PRASKDQVLSEPETK 438
L G P L SS ST P E R G G E P + P
Sbjct: 621 STLSG----PDLAGHSSSATST----PEELR-GYDSGPEGGAAASPPPDAELAACHPAAW 671
Query: 439 TMGKVSRFRIRRTPARP 455
+ G R P P
Sbjct: 672 SRGPAPPLAFRGAPGAP 688
Score = 65.9 bits (159), Expect = 1e-10
Identities = 102/402 (25%), Positives = 140/402 (34%), Gaps = 51/402 (12%)
Query: 17 RQPLTRALWGARSPKRPRLQLPGAPSPLEKASRRVLAVVLED----VMAVHMVPVVPSKQ 72
++P +R+L + +P L P P + + R A + + A+ V P ++
Sbjct: 235 QRPASRSLSSSATP----LSSPARSGPSARGTPRAPAHPSQPKPKGLQALRPPQVTPPRK 290
Query: 73 TSIPQHHSYHQDPVHRQPPASPPRQAGWSSQARPPDPLCLCREPLSRIHRTSSTLRRRSR 132
+ P P+ P A+P A SQA P P + H +S T +
Sbjct: 291 DAAPA-----LGPLSSSPLATPSPSAALQSQAPPTLP--------ATPHSSSLTCQL--- 334
Query: 133 TTPGPEEGPSQKVDRAPQPTLVVMLEDIASPRPPAEGFIDETPNFIIPAQRAEPMRIVRQ 192
TP P PS AP P+L + P PPA T + P +A +
Sbjct: 335 ATPLPLAPPSPS---AP-PSLQTL------PSPPATPPSQATTSLGSPTLQATHSFLP-- 382
Query: 193 PTPPPGDLEPPFQPSALPADPLESPPTAPDPALELPSTPPPSSLLRPRLSPWGLAPLFRS 252
PP P A P P ++PP P L+ P +PP S L P +P AP +
Sbjct: 383 --------SPPLSPLATP--PPQAPPALALPPLQAPPSPPASPPLSPLATPSPQAPNALA 432
Query: 253 VRSKLESFADIFLTPNKTPQPPPPSPPMKLELKIAISEAEQSGAAEGTASVSPRPPIRQW 312
V F+ P + P PP SPP+ S+A S AA V P PP
Sbjct: 433 VHLLQAPFSPPPSPPVQAPFSPPASPPVS-PSATPPSQAPPSLAAP-PLQVPPSPPASPP 490
Query: 313 RTQDHNTPALLPKPSLGRSYSCPDLGPPGPGTCTWPPAPPQPSRPRPRRHTVGGGEMARA 372
+ P P P P P PP PS P A
Sbjct: 491 MSPSATPPPQAPPPLAAPPLQLAKPPPQAPPALATPPLQALPSPPASFPGQAPFSPSASL 550
Query: 373 PPPPRPCLRKEVFPLGGVGASPSLTTSCSSTASTSFSEPAEP 414
P P + P V A+P L S AS + P P
Sbjct: 551 PMSPLATPPPQAPP---VLAAPLLQVPPSPPASPTLQAPRRP 589
Score = 52.0 bits (123), Expect = 2e-06
Identities = 106/400 (26%), Positives = 134/400 (33%), Gaps = 101/400 (25%)
Query: 4 PGDSSPPGQPRLCRQPLTRALWGARSPKRPRLQ-----LPGAP-SPLEKASRRVL-AVVL 56
P S+PP L P T S P LQ LP P SPL + A+ L
Sbjct: 343 PSPSAPPSLQTLPSPPATPPSQATTSLGSPTLQATHSFLPSPPLSPLATPPPQAPPALAL 402
Query: 57 EDVMAVHMVPVVP------SKQTSIPQHHSYHQDPVHRQPPASPPRQAGWSSQARPP--- 107
+ A P P + P + H PP SPP QA +S A PP
Sbjct: 403 PPLQAPPSPPASPPLSPLATPSPQAPNALAVHLLQAPFSPPPSPPVQAPFSPPASPPVSP 462
Query: 108 -------DPLCLCREPLSRIHRTSSTLRRRSRTTPGPEEGPSQKVDRAPQPTLVVMLEDI 160
P L PL ++ TP P+ AP P L+ +
Sbjct: 463 SATPPSQAPPSLAAPPLQVPPSPPASPPMSPSATPPPQ---------APPPLAAPPLQ-L 512
Query: 161 ASPRPPAEGFIDETPNFIIPAQRAEPMRIVRQPTPP---PGDLEPPFQPSA-LPADPLES 216
A P P A PA P++ + P+PP PG + PF PSA LP PL +
Sbjct: 513 AKPPPQAP-----------PALATPPLQAL--PSPPASFPG--QAPFSPSASLPMSPLAT 557
Query: 217 PPTAPDPALELP--------------------STP-PPSSLLRPRLSPWGLAPLFRSVRS 255
PP P L P TP P +S+ PRL+ LAP
Sbjct: 558 PPPQAPPVLAAPLLQVPPSPPASPTLQAPRRPPTPGPDTSVSGPRLT-LALAP------- 609
Query: 256 KLESFADIFLTPNKTPQPPPPSPPMKLELKIAISEAEQ----SGAAEGTASVSPRPPIRQ 311
P+++P P + A S E+ EG A+ SP P
Sbjct: 610 ------GPPPPPSRSPSSTLSGPDLAGHSSSATSTPEELRGYDSGPEGGAAASPPP---- 659
Query: 312 WRTQDHNTPALLPKP-SLGRSYSCPDLGPPGPGTCTWPPA 350
D A P S G + G PG WPPA
Sbjct: 660 ----DAELAACHPAAWSRGPAPPLAFRGAPG-APLPWPPA 694
Score = 43.9 bits (102), Expect = 4e-04
Identities = 115/449 (25%), Positives = 149/449 (33%), Gaps = 92/449 (20%)
Query: 1 MDLPGDSSPPGQPRLCRQPLTRALWGARSPKRPRLQLPGAPSPLEKASRRVLAVVLEDVM 60
MD D + G R P RA G +P+ P P P P+ A+ RVL
Sbjct: 1 MDNKRDKAKAGAA--ARTPAARAP-GLLTPRPPGSPRP--PPPVTPAALRVLGAA----G 51
Query: 61 AVHMVPVVPSKQ----TSIPQHHSYHQDPVHRQPPASPPRQAGWSSQ---ARPPDPLCLC 113
AV P+ +IP+ P A P R AG SS+ +RPP
Sbjct: 52 AVGRKPLAERAGGIGGATIPES----------APRAGPTRSAGTSSRNPASRPPASGRGE 101
Query: 114 REPLSRIHRTSSTLRRRSRTTPGPEEGPSQKVDRAPQPTLVVMLEDIASPRPPAEGFIDE 173
R P ++ T+PGP P + L I++ A G E
Sbjct: 102 RAPPAK------------NTSPGPVSSPGRASGTTRPGPLGQKGLRISAEETVARGKATE 149
Query: 174 TPNFIIPAQRAEPMRIVRQPT--PPPGDLEPPFQ----------------PSALPADPLE 215
P +R+ R+ T P PG P PSA P P E
Sbjct: 150 AP------KRSALSAGARRDTSGPTPGTPSPAMARRSRAAGTEVGLPRPAPSARPRPPTE 203
Query: 216 SPPTAPDPALELPST-PPPSSLLRPRLSPWGLAPLFRSVRSK---LESFADIFLTPNKTP 271
P + A E +T P P++ RP P RS+ S L S A + TP
Sbjct: 204 GPRKSVSSASEHSTTEPSPAARRRPSAGGGLQRPASRSLSSSATPLSSPARSGPSARGTP 263
Query: 272 QPPP-PSPPMKLELKI-----AISEAEQSGAAEGTASVSPRPPIRQWRTQDHNTPALLPK 325
+ P PS P L+ + + A G S SP P LP
Sbjct: 264 RAPAHPSQPKPKGLQALRPPQVTPPRKDAAPALGPLSSSPLATPSPSAALQSQAPPTLPA 323
Query: 326 PSLGRSYSCPDLGPPGPGTCTWPPAPPQPSRPRPRRHTVGGGEMARAPPPPRPCLRKEVF 385
S +C P P APP PS P P T+ P PP +
Sbjct: 324 TPHSSSLTCQLATP-------LPLAPPSPSAP-PSLQTL--------PSPPATPPSQATT 367
Query: 386 PLGGVGASPSLTTSCSSTASTSFSEPAEP 414
LG SP+L + S S S A P
Sbjct: 368 SLG----SPTLQATHSFLPSPPLSPLATP 392
Score = 30.0 bits (66), Expect = 6.2
Identities = 44/176 (25%), Positives = 62/176 (35%), Gaps = 29/176 (16%)
Query: 292 EQSGAAEGTASVSPRPPIRQWRTQDHNTPALLPKPSLGRSYSCPDLGPPGPGTCTWPPAP 351
+ SG GT S P R++ T LP+P+ P GP + +
Sbjct: 163 DTSGPTPGTPS-----PAMARRSRAAGTEVGLPRPAPSARPRPPTEGPRKSVSSASEHST 217
Query: 352 PQPSRPRPRRHTVGGGEMARAPPPPRPCLRKEVFPLGGVGASPSLTTSCSSTASTSFSEP 411
+PS RR + GGG RP R + S T SS A + S
Sbjct: 218 TEPSPAARRRPSAGGGLQ-------RPASR----------SLSSSATPLSSPARSGPSAR 260
Query: 412 AEPRLGSTKGKEPRASKDQVLSEPETKTMGKVSRFRIRRTPARPQLNLTPMGLPRP 467
PR +P+ Q L P+ V+ R PA L+ +P+ P P
Sbjct: 261 GTPR-APAHPSQPKPKGLQALRPPQ------VTPPRKDAAPALGPLSSSPLATPSP 309
>gi|239751637 PREDICTED: hypothetical protein FLJ22184 [Homo
sapiens]
Length = 1124
Score = 73.6 bits (179), Expect = 5e-13
Identities = 112/423 (26%), Positives = 142/423 (33%), Gaps = 78/423 (18%)
Query: 7 SSPPGQ--PRLCRQPLTRALWGARSPKRPRLQLPGAPSPLEKASRRVLAVVLEDVMAVHM 64
++PP Q P L PL G SP L P +P A + A
Sbjct: 588 ATPPPQAPPALASPPLQ----GLPSPPLSPLATPPPQAPPXLALPPLQAPPSPPASPPLS 643
Query: 65 VPVVPSKQTSIPQHHSYHQDPVHRQPPASPPRQAGWSSQARPPDPLCLCREPLSRIHRTS 124
PS Q P + H PP SPP QA +S A PP S
Sbjct: 644 PLATPSPQA--PNALAVHLLQAPFSPPPSPPVQAPFSPPASPP---------------VS 686
Query: 125 STLRRRSRTTPGPEEGPSQKVDRAPQPTLVVMLEDIASPRPPAEGFIDETPNFIIPAQRA 184
+ S+ P P Q P P + A+P P A + P + P+ A
Sbjct: 687 PSATPPSQAPPSLAAPPLQV---PPSPPASPPMSPSATPPPQAPPPLAAPPLQVPPSPPA 743
Query: 185 EPMRIVRQPTPP--------PGDLEPPFQPSALPADPLESPPTAPDPALELPSTPPPSSL 236
P PP P PP P++LP PL PP PAL +TPP +L
Sbjct: 744 SPPMSPSATPPPRVPPLLAAPPLQVPPSPPASLPMSPLAKPPPQAPPAL---ATPPLQAL 800
Query: 237 LRPRLSPWGLAPLFRSVRSKLESFADIFLTPNKTPQPPPPSPPMKLELKIAISEAEQSGA 296
P S G AP S A + ++P T PPP +PP+ L + + S
Sbjct: 801 PSPPASFPGQAPFSPS--------ASLPMSPLAT--PPPQAPPV---LAAPLLQVPPSPP 847
Query: 297 AEGTASVSPRPPIRQWRTQDHNTPALLPKPSLGRSYSCPDLGPPGPG-TCTWPPAPPQPS 355
A T RPP TP PD GP T P PP P
Sbjct: 848 ASPTLQAPRRPP----------TPG-------------PDTSVSGPRLTLALAPGPPPPP 884
Query: 356 RPRPRRHTVG---GGEMARAPPPPRPCLRKEVFPLGGVGASPSLTTSCSSTASTSFSE-P 411
P G G + A P + P GG ASP ++ ++S P
Sbjct: 885 SRSPSSTLSGPDLAGHSSSATSTPEELRGYDSGPEGGAAASPPPDAELAACHPAAWSRGP 944
Query: 412 AEP 414
A P
Sbjct: 945 APP 947
Score = 68.9 bits (167), Expect = 1e-11
Identities = 102/382 (26%), Positives = 134/382 (35%), Gaps = 42/382 (10%)
Query: 29 SPKRPRLQLPGAPSPLEKASRRVLAVVLEDVMAVHMVPVVPSKQTSIPQHHSYHQDPVHR 88
SP RP P +P PL+ A +P P QTS+ S P+
Sbjct: 443 SPSRPASTPPDSP-PLQ---------------APLSLPASPPLQTSLSPAVSPLSSPLTI 486
Query: 89 QPPASPPRQAGWSSQARPPDPLCLCREPLSRIHRTSSTLRRRSRTTPGPEEGPSQKVDRA 148
P + A S QA + E S + S S TTP E PS
Sbjct: 487 HPLQALSSLASHSPQAPLSSLIMPPLETQSSLAPPSLQTPPASLTTPPLENLPSLAPPPL 546
Query: 149 PQPTLVVMLEDIASPRPPAEGFIDETPNFIIPAQRAEPMRIVRQPTP-PPGDLEPPFQPS 207
+ + + +P PA + P+ + P I P PP PP Q
Sbjct: 547 QTASAPLTTPHLETPPCPAPCPLQAPPSPLTTPPPETPSSIATPPPQAPPALASPPLQ-- 604
Query: 208 ALPADPLES----PPTAPD----PALELPSTPPPSSLLRPRLSPWGLAPLFRSVRSKLES 259
LP+ PL PP AP P L+ P +PP S L P +P AP +V
Sbjct: 605 GLPSPPLSPLATPPPQAPPXLALPPLQAPPSPPASPPLSPLATPSPQAPNALAVHLLQAP 664
Query: 260 FADIFLTPNKTPQPPPPSPPMKLELKIAISEAEQSGAAEGTASVSPRPPIRQWRTQDHNT 319
F+ P + P PP SPP+ S+A S AA V P PP +
Sbjct: 665 FSPPPSPPVQAPFSPPASPPVS-PSATPPSQAPPSLAAP-PLQVPPSPP-----ASPPMS 717
Query: 320 PALLPKPSLGRSYSCPDLG-PPGPGTCTWPPAPPQ--PSRPRPRRHTVGGGEMARAPPPP 376
P+ P P + P L PP P P +PP + P PR + + PP P
Sbjct: 718 PSATPPPQAPPPLAAPPLQVPPSP-----PASPPMSPSATPPPRVPPLLAAPPLQVPPSP 772
Query: 377 RPCLRKEVFPLGGVGASPSLTT 398
L A P+L T
Sbjct: 773 PASLPMSPLAKPPPQAPPALAT 794
Score = 60.1 bits (144), Expect = 6e-09
Identities = 117/506 (23%), Positives = 173/506 (34%), Gaps = 100/506 (19%)
Query: 38 PGAPSP-LEKASRRVLAVVLEDVMAVHMVPVVPSKQ-----TSIPQHHSYHQDPVHRQPP 91
PG PSP + + SR V A P P++ +S +H + P R+ P
Sbjct: 169 PGTPSPAMARRSRAAGTEVGLPRPAPSARPRPPTEGPRKSVSSASEHSTTEPSPAARRRP 228
Query: 92 ASPPRQAGWSSQARPPDPLCLCREPLSRIHRTSSTLRRRSRTTPGPEEGPSQKVDRAPQP 151
+ AG Q L PLS R+ + R R P + + + P
Sbjct: 229 S-----AGGGLQRPASRSLSSSATPLSSPARSGPSARGTPRAPAHPSQPKPKGLQALRPP 283
Query: 152 TLVVMLEDIASPRPPAEGFIDETPNFIIPAQRAEPMRIVRQPTPPPGDLEPPFQPSALPA 211
+ +D A PA G + +P P +P PPP + P + P+
Sbjct: 284 QVTPPRKDAA----PALGPLSSSP-----LATPSPSGTKARPVPPPDNAATPLPATLPPS 334
Query: 212 DPLESP-------PTAPDPALELPSTP-------PPSSLLRPRLSPWGL----------- 246
PL +P P+AP LPS P PPS P +P L
Sbjct: 335 PPLATPLPLAPPSPSAPPSLQTLPSPPATPPSQAPPSMTTPPMQAPPSLQTIPPIQVPHS 394
Query: 247 -------APLFRSVRSKLESFADI----------FLT------------PNKTPQPPPPS 277
AP S L++ + FLT P++ PP S
Sbjct: 395 LTSPSLQAPPSPLALSSLQATTSLGSPTLQATHSFLTMSPRQTQASLTSPSRPASTPPDS 454
Query: 278 PPMKLELKIAISEAEQSGAAEGTASVS------PRPPIRQWRTQDHNTP---ALLPKPSL 328
PP++ L + S Q+ + + +S P + + P ++P
Sbjct: 455 PPLQAPLSLPASPPLQTSLSPAVSPLSSPLTIHPLQALSSLASHSPQAPLSSLIMPPLET 514
Query: 329 GRSYSCPDLGPPGPGTCTWPPAPPQPSRPRPRRHTVGG---GEMARAPPPPRPCLRKEVF 385
S + P L P P + T PP PS P T PP P PC
Sbjct: 515 QSSLAPPSLQTP-PASLTTPPLENLPSLAPPPLQTASAPLTTPHLETPPCPAPC------ 567
Query: 386 PLGGVGASPS-LTTSCSSTASTSFSEP--AEPRLGSTKGKEPRASKDQVLSEPETKTMGK 442
PL A PS LTT T S+ + P A P L S + + L+ P +
Sbjct: 568 PL---QAPPSPLTTPPPETPSSIATPPPQAPPALASPPLQGLPSPPLSPLATPPPQAPPX 624
Query: 443 VSRFRIRRTPARP-QLNLTPMGLPRP 467
++ ++ P+ P L+P+ P P
Sbjct: 625 LALPPLQAPPSPPASPPLSPLATPSP 650
Score = 50.1 bits (118), Expect = 6e-06
Identities = 81/334 (24%), Positives = 113/334 (33%), Gaps = 65/334 (19%)
Query: 271 PQPPPPSPPMKLELKIAISEAEQSGAAEGTASVSPRPPIRQWR-----TQDHNT----PA 321
P P PSP M + A +E G S PRPP R +H+T PA
Sbjct: 167 PTPGTPSPAMARRSRAAGTEV---GLPRPAPSARPRPPTEGPRKSVSSASEHSTTEPSPA 223
Query: 322 LLPKPSLGR----------SYSCPDLGPP---GPGTCTWPPAPPQPSRPRPRRHTVGGGE 368
+PS G S S L P GP P AP PS+P+P+ G
Sbjct: 224 ARRRPSAGGGLQRPASRSLSSSATPLSSPARSGPSARGTPRAPAHPSQPKPK------GL 277
Query: 369 MARAPPPPRPCLRKEVFPLGGVGASPSLTTSCSSTASTSFSEP--AEPRLGSTKGKEPRA 426
A PP P + LG + +SP T S S T + P A L +T P
Sbjct: 278 QALRPPQVTPPRKDAAPALGPLSSSPLATPSPSGTKARPVPPPDNAATPLPATLPPSPPL 337
Query: 427 SKDQVLSEPETKTMGKVSRF----RIRRTPARPQLNLTPMGLP------RPIRL------ 470
+ L+ P + + A P + PM P PI++
Sbjct: 338 ATPLPLAPPSPSAPPSLQTLPSPPATPPSQAPPSMTTPPMQAPPSLQTIPPIQVPHSLTS 397
Query: 471 -----NKKEFSLEEIYTNKNYQSPTTRRTFETIFEEPRERNGTLIFTSSRKLRRAVEFRD 525
+L + + SPT + T + PR+ +L S R
Sbjct: 398 PSLQAPPSPLALSSLQATTSLGSPTLQATHSFLTMSPRQTQASLTSPS----------RP 447
Query: 526 SSLPRSRRPSRGVRAAGGRTVPPNVAPSPDVGPL 559
+S P P + + + P + SP V PL
Sbjct: 448 ASTPPDSPPLQAPLSLPA-SPPLQTSLSPAVSPL 480
Score = 36.6 bits (83), Expect = 0.066
Identities = 36/125 (28%), Positives = 45/125 (36%), Gaps = 20/125 (16%)
Query: 267 PNKTPQPPPPSPPMKLELKIAISE------AEQSGAAEGTASVSPRP---PIRQWRTQDH 317
P +P+PPPP P L + A AE++G G P P R T
Sbjct: 29 PPGSPRPPPPVTPAALRVLGAAGAVGRKPLAERAGGIGGATIPESAPRAGPTRSAGTSSR 88
Query: 318 NTPALLPKPSLGRSYSCPDLGPPGPGTCTWPPAPPQPSRPRP---------RRHTVGGGE 368
N PA P P+ GR P PG + P +RP P TV G+
Sbjct: 89 N-PASRP-PASGRGERAPPAKNTSPGPVSSPGRASGTTRPGPLGQKGLRISAEETVARGK 146
Query: 369 MARAP 373
AP
Sbjct: 147 ATEAP 151
>gi|148762969 myeloid/lymphoid or mixed-lineage leukemia 2 [Homo
sapiens]
Length = 5537
Score = 72.0 bits (175), Expect = 1e-12
Identities = 107/410 (26%), Positives = 153/410 (37%), Gaps = 64/410 (15%)
Query: 38 PGAPSPLEKASRRV--LAVVLEDVMAVHMVPVVPSKQTSIPQHHSYHQDPVHRQPPASPP 95
P P PL+ ++ + V LE + + +P +P P + P SPP
Sbjct: 406 PKEPGPLQCEAKPLGKAGVQLEPQLEAPLNEEMPL----LPPPEESPLSPPPEESPTSPP 461
Query: 96 RQAGWSSQARPPDPLCLCREPLSRIHRTSSTLRRRSRTTPGPEEGPSQKVDRAPQPTLVV 155
+A S+ PP P L PL S L S +P PEE P +P P
Sbjct: 462 PEA---SRLSPP-PEELPASPLPEALHLSRPLEE-SPLSPPPEESPL-----SPPPE--- 508
Query: 156 MLEDIASPRPPAEGFIDETPNFIIPAQRAEPMRIVRQPTPPPGD---LEPPFQPSALPAD 212
+SP P E E+P + P + + P + P PP + L PPF+ S L +
Sbjct: 509 -----SSPFSPLE----ESP--LSPPEESPPSPALETPLSPPPEASPLSPPFEESPL-SP 556
Query: 213 PLESPPTAPDPALELPSTPPPSSLLR--PRLSPWGLAPLFRSVRSKLESFADIFLTPNKT 270
P E PT+P P S PP S + P SP P + E + + P ++
Sbjct: 557 PPEELPTSPPPEASRLSPPPEESPMSPPPEESPMSPPPEASRLFPPFEE-SPLSPPPEES 615
Query: 271 PQPPPPS------PPMKLELKIAISEAEQSGAAEGTASVSPRPPIRQWRTQDHNTPALLP 324
P PPP PP + E+ S E + +SP P + + +P L P
Sbjct: 616 PLSPPPEASRLSPPPEDSPMSPPPEESPMSPPPE-VSRLSPLPVVSRLSPPPEESP-LSP 673
Query: 325 KPSLGRSYSCPD---LGPPGPGTCTWPPAPPQPSRPRPRRHTVG----GGEMARAPPPPR 377
P + P+ L PP + T PP P+ P P + + P P+
Sbjct: 674 PPEESPTSPPPEASRLSPPPEDSPTSPPPEDSPASPPPEDSLMSLPLEESPLLPLPEEPQ 733
Query: 378 PCLRKEVFPLGGVGASPSLTTSCSSTASTSFSEPAEPRLGSTKGKEPRAS 427
C R E L P L+ P EP L S + +EP S
Sbjct: 734 LCPRSEGPHLSPRPEEPHLS-----------PRPEEPHL-SPQAEEPHLS 771
Score = 61.2 bits (147), Expect = 2e-09
Identities = 82/322 (25%), Positives = 113/322 (35%), Gaps = 23/322 (7%)
Query: 69 PSKQTSIPQHHSYHQDPVHRQPPASPPRQAGWSSQARPPDPLCLCRE-PLSRIHRTSSTL 127
P + + P + H + P SPP + S P E PLS + +
Sbjct: 471 PEELPASPLPEALHLSRPLEESPLSPPPEESPLSPPPESSPFSPLEESPLSPPEESPPSP 530
Query: 128 RRRSRTTPGPEEGP-SQKVDRAPQPTLVVMLEDIASPRPPAEGFIDETPNF--IIPAQRA 184
+ +P PE P S + +P L E++ + PP + P + P
Sbjct: 531 ALETPLSPPPEASPLSPPFEESP---LSPPPEELPTSPPPEASRLSPPPEESPMSPPPEE 587
Query: 185 EPMRIVRQPTPPPGDLEPPFQPSALPADPLESPPTAPDPALELPSTPPPSSLLRPRLSPW 244
PM P P L PPF+ S L P ESP + P A L S PP S + P
Sbjct: 588 SPM----SPPPEASRLFPPFEESPLSPPPEESPLSPPPEASRL-SPPPEDSPMSPPPEES 642
Query: 245 GLAPLFRSVR-SKLESFADIFLTPNKTPQPPPP-----SPPMKLELKIAISEAEQSGAAE 298
++P R S L + + P ++P PPP SPP + E +
Sbjct: 643 PMSPPPEVSRLSPLPVVSRLSPPPEESPLSPPPEESPTSPPPEASRLSPPPEDSPTSPPP 702
Query: 299 GTASVSPRPPIRQWRTQDHNTPALLPKPSLGRSYSCPDLGPPGPGTCTWPPAPPQPSRPR 358
+ SP P +P LLP P CP GP P P RP
Sbjct: 703 EDSPASPPPEDSLMSLPLEESP-LLPLPE--EPQLCPR--SEGPHLSPRPEEPHLSPRPE 757
Query: 359 PRRHTVGGGEMARAPPPPRPCL 380
+ E +P P PCL
Sbjct: 758 EPHLSPQAEEPHLSPQPEEPCL 779
Score = 58.2 bits (139), Expect = 2e-08
Identities = 104/415 (25%), Positives = 148/415 (35%), Gaps = 69/415 (16%)
Query: 30 PKRPRLQLPGAPSPLEKASRRVLAVVLEDVMAVHMVPVVPSKQTSIPQHHSYHQDPVHRQ 89
P PR Q P P P K L D +AV P V + S +P+
Sbjct: 2231 PGTPRHQ-PSTPDPFLKPRCPSL-----DNLAVPESPGVGGGKAS---------EPLLSP 2275
Query: 90 PPASPPRQA--------GWSSQARPPDPLCLCREPLSRIHRTSSTLRR----RSRTTPGP 137
PP R+A G SS + P L P S H L+ ++ TP
Sbjct: 2276 PPFGESRKALEVKKEELGASSPSYGPPNLGFVDSPSSGTHLGGLELKTPDVFKAPLTPRA 2335
Query: 138 EEGPSQKVDRAPQPTLVVMLEDIASPRPPAEGFIDETPNFIIPAQRAEPMR---IVRQPT 194
+ Q +P + +A P PP+ P+ P +P + +P
Sbjct: 2336 SQVEPQSPGLGLRPQEPPPAQALA-PSPPSH------PDIFRPGSYTDPYAQPPLTPRPQ 2388
Query: 195 PPPGDLEPPFQPSALPADPLESPPTAPDPALELPSTPPPSSLLRPRLSPWGLAPLFRS-- 252
PPP + P +LP+DP P +P S P L P + P F+S
Sbjct: 2389 PPPPESCCALPPRSLPSDPFSRVPASPQSQSSSQSPLTPRPLSAEAFCPSPVTPRFQSPD 2448
Query: 253 ----VRSKLESFADIFLTPNKTPQPPPPSPPMKLELKIAISEAEQSGAAEGTASVSPRPP 308
S+ +S D F +K P+P PP K A S A S A G + P P
Sbjct: 2449 PYSRPPSRPQS-RDPFAPLHKPPRPQPPEVAFK-----AGSLAHTSLGAGGFPAALPAGP 2502
Query: 309 IRQWRTQDHNTPALLPKPSLGRSYSCPDLGPPGPGTCTWPPAPPQPSRPRPRRHTVGGGE 368
+ + P+ P P+ RS PG G P+P + + P+ GE
Sbjct: 2503 AGELHAK---VPSGQP-PNFVRS--------PGTGAFVGTPSPMRFTFPQ------AVGE 2544
Query: 369 MARAPPPPRPCLRKEVFPLGGVGASPSL--TTSCSSTASTSFSEPAEPRLGSTKG 421
+ PP P+P L G P+L S + T +T P+ LG + G
Sbjct: 2545 PSLKPPVPQPGLPPPHGINSHFGPGPTLGKPQSTNYTVATGNFHPSGSPLGPSSG 2599
Score = 55.1 bits (131), Expect = 2e-07
Identities = 113/460 (24%), Positives = 164/460 (35%), Gaps = 88/460 (19%)
Query: 7 SSPPGQPRLCRQPLTRALWGARSPKRPRLQ-LPGAPSPLEKASRRVLAVVLEDVMAVHMV 65
S PP RL P SP P + P +P P + ++++ LE+ + +
Sbjct: 681 SPPPEASRLSPPP-------EDSPTSPPPEDSPASPPPEDS----LMSLPLEESPLLPL- 728
Query: 66 PVVPSKQTSIPQHHSYHQDPVHRQPPASP-PRQAGWSSQARPP------DPLCLCREPLS 118
P + P+ H P +P SP P + S QA P + CLC P
Sbjct: 729 ---PEEPQLCPRSEGPHLSPRPEEPHLSPRPEEPHLSPQAEEPHLSPQPEEPCLCAVP-E 784
Query: 119 RIHRTSSTLRRRSRTTPGPEEGPSQKVDRAPQPTLVVMLEDIASPRPPAEGFIDETPNFI 178
H + +P PEE + +P L + E+ P E +
Sbjct: 785 EPHLSPQA--EGPHLSPQPEE--LHLSPQTEEPHLSPVPEEPCLSPQPEESHLSPQSEEP 840
Query: 179 IPAQRAEPMRI---VRQPTPPPGDLEPPFQPSALPAD---PLESPPTAP-------DPAL 225
+ R E + + +P P +PP +P PA PL PP P +PAL
Sbjct: 841 CLSPRPEESHLSPELEKPPLSPRPEKPPEEPGQCPAPEELPLFPPPGEPSLSPLLGEPAL 900
Query: 226 ELPSTPPPSSLLRPRLSPWGLAPLFRSVRSKLESFADIFLTPNKTPQPPPPSPPMKLELK 285
P PP S L P P L+P S S + + P+ P PPP SP +
Sbjct: 901 SEPGEPPLSPL--PEELP--LSP------SGEPSLSPQLMPPD--PLPPPLSPIITAAAP 948
Query: 286 IAIS---EAEQSGAAEGTASVSPRPPIRQWRTQDHNTPALLPKPSLGRSYSCPDLGPPGP 342
A+S E E A+G + P P+ +L P + PP
Sbjct: 949 PALSPLGELEYPFGAKGDSD--PESPL---------AAPILETP----------ISPPPE 987
Query: 343 GTCTWP-PAPPQPSRPRPRRHTVGGGEMARAPPPPR--PCLRKEVFPLGGVGAS---PSL 396
CT P P PP P P + P PP+ P L+ + P + P+L
Sbjct: 988 ANCTDPEPVPPMILPPSPGSPVGPASPILMEPLPPQCSPLLQHSLVPQNSPPSQCSPPAL 1047
Query: 397 TTSCSSTASTSFSEPAEPRLGSTKGKEPRASKDQVLSEPE 436
S S S P +G + E + + +SEPE
Sbjct: 1048 PLSVPSPLS-----PIGKVVGVSDEAELHEMETEKVSEPE 1082
Score = 48.5 bits (114), Expect = 2e-05
Identities = 86/356 (24%), Positives = 120/356 (33%), Gaps = 70/356 (19%)
Query: 2 DLPGDSSP----PGQPRLCRQPLTRALWGARSPKR-PRLQ----LPGAP--SPLEKASRR 50
D PG + P QP L R G + PK P LQ LPG + + +
Sbjct: 4143 DQPGSMTQNLLGPQQPMLERPMQNNT--GPQPPKPGPVLQSGQGLPGVGIMPTVGQLRAQ 4200
Query: 51 VLAVVLEDVMAVHMVPVVPSKQTSIPQHHSYHQDPVHRQPPASPPRQAGWSSQARPPDPL 110
+ V+ ++ H+ P + ++ Q RQ P P ++ G +Q P L
Sbjct: 4201 LQGVLAKNPQLRHLSPQQQQQLQALLMQRQLQQSQAVRQTP--PYQEPG--TQTSPLQGL 4256
Query: 111 CLCREPLSRIHRTSSTLRRRSRTTPGPEEGPSQKVDRAPQPTLVVMLEDIASPRPPAEGF 170
C+ L PGP+ GP Q++ P+P PR PA
Sbjct: 4257 LGCQPQLGGF--------------PGPQTGPLQELGAGPRPQ--------GPPRLPAPPG 4294
Query: 171 IDETPNFIIPAQRAEPMRIVRQPTPPPGDLEPPFQPSALPADPLESPPTAPDPALELPST 230
T + P PTPPP + P +PS LP+ + P A P P T
Sbjct: 4295 ALSTGPVLGPVH----------PTPPPSSPQEPKRPSQLPSPSSQLPTEAQLPPTH-PGT 4343
Query: 231 PPPSSLLRPRLSPWGLAPLFRSVRSKLESFADIFLTPNKTPQPPPPSPPMKLELKIAISE 290
P P P L P P R V AD + P PP + +
Sbjct: 4344 PKPQG---PTLEP----PPGR-VSPAAAQLADTLFSKGLGPWDPPDN-------LAETQK 4388
Query: 291 AEQSGAAEG-----TASVSPRPPIRQWRTQDHNTPALLPKPSLGRSYSCPDLGPPG 341
EQS G V P + + P L S+ R + +G PG
Sbjct: 4389 PEQSSLVPGHLDQVNGQVVPEASQLSIKQEPREEPCALGAQSVKREANGEPIGAPG 4444
Score = 47.4 bits (111), Expect = 4e-05
Identities = 121/531 (22%), Positives = 177/531 (33%), Gaps = 116/531 (21%)
Query: 1 MDLPGDSSP----PGQPRLCRQPLTRALWGARSPKRPRLQ-LPGAPSPLEKASRRVLAVV 55
M LP + SP P +P+LC P + + P+ P L P P +A L+
Sbjct: 716 MSLPLEESPLLPLPEEPQLC--PRSEGPHLSPRPEEPHLSPRPEEPHLSPQAEEPHLSPQ 773
Query: 56 LED--VMAV----HMVPVV--------PSKQTSIPQHHSYHQDPVHRQPPASP-PRQAGW 100
E+ + AV H+ P P + PQ H PV +P SP P ++
Sbjct: 774 PEEPCLCAVPEEPHLSPQAEGPHLSPQPEELHLSPQTEEPHLSPVPEEPCLSPQPEESHL 833
Query: 101 SSQARPPDPLCLCREPLSRIHRTSSTLRRRSRTTPGPEEGPSQKVDRAPQPTLVVMLEDI 160
S Q+ P C P S L + +P PE+ P ++ + P P E++
Sbjct: 834 SPQSEEP-----CLSPRPEESHLSPELEKPP-LSPRPEK-PPEEPGQCPAP------EEL 880
Query: 161 ASPRPPAEGFIDETPNFIIPAQRAEP-MRIVRQPTPPPGDLEPPFQPSALPADPL----- 214
PP E + ++ EP + + + P EP P +P DPL
Sbjct: 881 PLFPPPGEPSLSPLLGEPALSEPGEPPLSPLPEELPLSPSGEPSLSPQLMPPDPLPPPLS 940
Query: 215 -------------------------ESPPTAP--DPALELPSTPPPSS----------LL 237
+S P +P P LE P +PPP + ++
Sbjct: 941 PIITAAAPPALSPLGELEYPFGAKGDSDPESPLAAPILETPISPPPEANCTDPEPVPPMI 1000
Query: 238 RPRLSPWGLAPLFRSVRSKLESFADIFLTPNKTPQPPPPS--PPMKLELKIAISEAEQSG 295
P + P + L L + PQ PPS P L L + S G
Sbjct: 1001 LPPSPGSPVGPASPILMEPLPPQCSPLLQHSLVPQNSPPSQCSPPALPLSVP-SPLSPIG 1059
Query: 296 AAEGTASVSPRPPIRQWRTQDHNTPALLPK-----PSLGRSYSCPDLGP-------PGPG 343
G + + + + + PAL P PS SCP P G G
Sbjct: 1060 KVVGVSDEAELHEMETEKVSEPECPALEPSATSPLPSPMGDLSCPAPSPAPALDDFSGLG 1119
Query: 344 TCTWP----PAP---PQPSR-PRPRRHTVGGGEMARAPPPPRPCLRKEVFPLGGVGASPS 395
T P AP P+P + P + G + P P EV+P
Sbjct: 1120 EDTAPLDGIDAPGSQPEPGQTPGSLASELKGSPVLLDPEELAPVTPMEVYP--------- 1170
Query: 396 LTTSCSSTA--STSFSEPAEPRLGSTKGKEPRASKDQVLSEPETKTMGKVS 444
C TA + E EPR P K +++E + G S
Sbjct: 1171 ---ECKQTAGQGSPCEEQEEPR-APVAPTPPTLIKSDIVNEISNLSQGDAS 1217
Score = 42.7 bits (99), Expect = 0.001
Identities = 88/332 (26%), Positives = 114/332 (34%), Gaps = 78/332 (23%)
Query: 189 IVRQPTPPPGDLEPPFQPSALPADPLESPPTAPDPALELPSTPPPSSLLRPRLSPWGLAP 248
I R+ P L P QP AL + P P AP + P+TP
Sbjct: 2093 IARKTDRPALHLRIPPQPGALGSPP---PAAAPTIFIGSPTTP----------------- 2132
Query: 249 LFRSVRSKLESFADIFLTPNKTPQPPPPSPP---MKLELKIAISEAEQSGAAEGTA-SVS 304
+ L + AD FL P P P SP +KL ++ Q A +
Sbjct: 2133 ------AGLSTSADGFLKPPAGSVPGPDSPGELFLKLPPQVPAQVPSQDPFGLAPAYPLE 2186
Query: 305 PRPPIRQWRTQDHNTPALLP--KPSLGRSYSCPDLGPPG------PGTCTWPPAPPQP-S 355
PR P + +P P P LG S S P G PG PGT P+ P P
Sbjct: 2187 PRFPTAPPTYPPYPSPTGAPAQPPMLGAS-SRPGAGQPGEFHTTPPGTPRHQPSTPDPFL 2245
Query: 356 RPR---------PRRHTVGGGEMAR---APPP---PRPCLRKEVFPLGGVGAS---PSLT 397
+PR P VGGG+ + +PPP R L + LG S P+L
Sbjct: 2246 KPRCPSLDNLAVPESPGVGGGKASEPLLSPPPFGESRKALEVKKEELGASSPSYGPPNLG 2305
Query: 398 TSCSSTASTSFSEPAEPRLGSTKGKEPRASKDQVLSEPETKTMGKVSRFRIRRTPARPQL 457
S ++ T LG + K P V P T +V P P L
Sbjct: 2306 FVDSPSSGT--------HLGGLELKTP-----DVFKAPLTPRASQVE-------PQSPGL 2345
Query: 458 NLTPMGLPRPIRLNKKEFSLEEIYTNKNYQSP 489
L P P L S +I+ +Y P
Sbjct: 2346 GLRPQEPPPAQALAPSPPSHPDIFRPGSYTDP 2377
Score = 40.4 bits (93), Expect = 0.005
Identities = 79/315 (25%), Positives = 109/315 (34%), Gaps = 42/315 (13%)
Query: 165 PPAEGFIDETPNFIIPAQRAEPMRIVRQPTPPPGDLEPPFQPSALPADPLESPPTAPDPA 224
PP G + P PA A P + PT P G + AD PP P
Sbjct: 2107 PPQPGALGSPP----PA--AAPTIFIGSPTTPAG--------LSTSADGFLKPPAGSVPG 2152
Query: 225 LELPST-----PPPSSLLRPRLSPWGLAPLFRSVRSKLESFADIFLTPNKTPQPPPPSPP 279
+ P PP P P+GLAP + + + + + P +P P PP
Sbjct: 2153 PDSPGELFLKLPPQVPAQVPSQDPFGLAPAY-PLEPRFPTAPPTY-PPYPSPTGAPAQPP 2210
Query: 280 MKLELKIAISEAEQSGAAEGTASVSPRPPIRQWRTQDHNTPALLPK-PSLGRSYSCPDLG 338
M + S +G + P P Q T D P L P+ PSL + + P+
Sbjct: 2211 M-----LGASSRPGAGQPGEFHTTPPGTPRHQPSTPD---PFLKPRCPSLD-NLAVPESP 2261
Query: 339 PPGPGTCTWPPAPPQPSRPRPRRHTVGGGEM-ARAPPPPRPCLRKEVFP-----LGGVGA 392
G G + P P P + V E+ A +P P L P LGG+
Sbjct: 2262 GVGGGKASEPLLSPPPFGESRKALEVKKEELGASSPSYGPPNLGFVDSPSSGTHLGGLEL 2321
Query: 393 SPSLTTSCSSTASTSFSEPAEPRLGSTKGKEPRASKDQVLSEPETKTMGKVSRFRIRRTP 452
T S EP P LG + +EP ++ S P + + + T
Sbjct: 2322 KTPDVFKAPLTPRASQVEPQSPGLG-LRPQEPPPAQALAPSPPSHPDIFRPGSY----TD 2376
Query: 453 ARPQLNLTPMGLPRP 467
Q LTP P P
Sbjct: 2377 PYAQPPLTPRPQPPP 2391
Score = 32.7 bits (73), Expect = 0.95
Identities = 43/177 (24%), Positives = 63/177 (35%), Gaps = 54/177 (30%)
Query: 232 PPSSLLRPRLSPWGLAPLFRSVRSKLESFADIFLTPNKTPQPPPPSPPMKLELKIAISEA 291
PPS L P L P F + ++ +PPPP+ P ++ ++
Sbjct: 2752 PPSKLSGPILGPGS------------------FPSDDRLSRPPPPATPSSMD----VNSR 2789
Query: 292 EQSGAAEGTASVSPRP---PIRQ-----WRTQDHNTPALL-----------PKPSLGR-S 331
+ G ++ +P P P++Q W+ Q + P P LGR +
Sbjct: 2790 QLVGGSQAFYQRAPYPGSLPLQQQQQQLWQQQQATAATSMRFAMSARFPSTPGPELGRQA 2849
Query: 332 YSCPDLG----PPGPGTCTWPPAPPQPSRPRPRRHTV------GGGEMARAPPPPRP 378
P G PGPG P P P++ RH V GG PP RP
Sbjct: 2850 LGSPLAGISTRLPGPGEPV--PGPAGPAQFIELRHNVQKGLGPGGTPFPGQGPPQRP 2904
Score = 32.0 bits (71), Expect = 1.6
Identities = 29/68 (42%), Positives = 33/68 (48%), Gaps = 9/68 (13%)
Query: 190 VRQ-PTPPPGDLEPPFQPSALPADPLESPPTAPDPALELPSTPPPSSLLRPRLSPWGLAP 248
VRQ PPP + PP PS L P SPPT +P +ELP+ P P SP LA
Sbjct: 4903 VRQLSAPPPEEPSPP--PSPLAPSP-ASPPT--EPLVELPTEPLAEP---PVPSPLPLAS 4954
Query: 249 LFRSVRSK 256
S R K
Sbjct: 4955 SPESARPK 4962
Score = 31.6 bits (70), Expect = 2.1
Identities = 23/86 (26%), Positives = 36/86 (41%), Gaps = 15/86 (17%)
Query: 175 PNFIIPAQRAEPMRIVRQPTPPPGDLEPPFQPS-----------ALPADPLESPPTAPDP 223
P + + +Q + + +++Q +P P EPP Q S L A P E P P P
Sbjct: 4865 PGYTLKSQ-LDILSLLKQESPAP---EPPTQHSYTYNVSNLDVRQLSAPPPEEPSPPPSP 4920
Query: 224 ALELPSTPPPSSLLRPRLSPWGLAPL 249
P++PP L+ P P+
Sbjct: 4921 LAPSPASPPTEPLVELPTEPLAEPPV 4946
>gi|47132519 Ras association and pleckstrin homology domains 1 isoform
1 [Homo sapiens]
Length = 1250
Score = 70.5 bits (171), Expect = 4e-12
Identities = 102/401 (25%), Positives = 141/401 (35%), Gaps = 101/401 (25%)
Query: 90 PPASPPRQAGWSSQARPPD-----PLCLCREPLSRIHRTSSTLRRRSRTTPGPEEGPSQK 144
PP PP +Q +P P P +IH+ + T P P P+
Sbjct: 714 PPPPPPTPGSAMAQLKPAPCAPSLPQFSAPPPPLKIHQVQHITQVAPPTPPPPPPIPAPL 773
Query: 145 VDRAPQPTLVVMLEDIASPRPPAEGFIDETPNFIIPAQRAEPMRIVRQPTPP--PGDLEP 202
+AP LV + P P + + + Q A P PTPP P +P
Sbjct: 774 PPQAPPKPLVTI------PAPTSTKTVAP-----VVTQAAPPT-----PTPPVPPAKKQP 817
Query: 203 PFQPSALPADPLESPPTAPDPALELPST----PPPSSLLRPRLSPWGLAPLFRSVRSKLE 258
F S +P P P P P L + PPPS L SP V S ++
Sbjct: 818 AFPASYIPPSPPTPPVPVPPPTLPKQQSFCAKPPPSPL-----SP---------VPSVVK 863
Query: 259 SFADIFLTPNKTPQPPPPSPPMKLELKIAISEAEQSGAAEGTASVSPRPPIRQWRTQDHN 318
A F PPPP+PP E A+V+P+ P + +
Sbjct: 864 QIASQF--------PPPPTPPAM----------ESQPLKPVPANVAPQSPPAV-KAKPKW 904
Query: 319 TPALLPKPSLGRSYSCPDLGPPGP-GTCTWPPAPPQPSRPRPRRHTVGGGEMARAPPPPR 377
P+ +P PS PD PP P + +PP PP P P P PPPP
Sbjct: 905 QPSSIPVPS-------PDFPPPPPESSLVFPPPPPSPV-PAP-------------PPPPP 943
Query: 378 PCLRKEVFPLGGVGASPSLTTS------------CSSTASTSFSEPAEPRLGSTKGKEPR 425
P G G S T+S SS S+S +E EP+ S +
Sbjct: 944 PTASPTPDKSGSPGKKTSKTSSPGGKKPPPTPQRNSSIKSSSGAEHPEPKRPSVDSLVSK 1003
Query: 426 ASKDQVLSEPETKTMGKVSRFRIRRTPARP-QLNLTPMGLP 465
+ P +T+ + P +P +LNL+ + LP
Sbjct: 1004 FTPPAESGSPSKETLPPPA------APPKPGKLNLSGVNLP 1038
Score = 59.7 bits (143), Expect = 7e-09
Identities = 110/477 (23%), Positives = 167/477 (35%), Gaps = 85/477 (17%)
Query: 30 PKRPRLQLPGAPSPLEKASRRVLAVVLEDVMAVHMVPVVPSK-QTSIPQHH---SYHQDP 85
P+ P L P+P +++ V VV + PV P+K Q + P + S P
Sbjct: 775 PQAPPKPLVTIPAPT--STKTVAPVVTQAAPPTPTPPVPPAKKQPAFPASYIPPSPPTPP 832
Query: 86 VHRQPPASPPRQAGWSSQARPPDPLCLCREPLSRIHRTSSTLRRRSRTTPGPEEGPSQKV 145
V PP P +Q S A+PP PLS + + + P P SQ +
Sbjct: 833 VPVPPPTLPKQQ---SFCAKPPP------SPLSPVPSVVKQIASQFPPPPTPPAMESQPL 883
Query: 146 DRAPQPTLVVMLEDIASPRPPAEGFIDETPNFIIPAQRAEPMRIVRQPTPPPGDLEPPFQ 205
P ++A PPA + P + P+ P P P + PP
Sbjct: 884 KPVPA--------NVAPQSPPA---VKAKPKWQ-PSSIPVPSPDFPPPPPESSLVFPPPP 931
Query: 206 PSALPADPLESPPTA---PD----PALELPST-------PPPSSLLRPRLSPWGLAPLFR 251
PS +PA P PPTA PD P + T PPP+ + A
Sbjct: 932 PSPVPAPPPPPPPTASPTPDKSGSPGKKTSKTSSPGGKKPPPTPQRNSSIKSSSGAEHPE 991
Query: 252 SVRSKLESFADIFLTPNKTPQP-----PPPSPPMKLELKIAISEAEQSGAAEGTASVSPR 306
R ++S F P ++ P PPP+ P K K+ +S G + VS +
Sbjct: 992 PKRPSVDSLVSKFTPPAESGSPSKETLPPPAAPPKPG-KLNLSGVNLPGVLQ-QGCVSAK 1049
Query: 307 PPIRQWRTQDHNTPALLPKPSLGRSYSCPDLGPPGPGTCTWPPAPPQPSRPRP--RRHTV 364
P+ R +D + P P P +PP PP+ P P V
Sbjct: 1050 APVLSGRGKD--SVVEFPSP---------------PSDSDFPPPPPETELPLPPIEIPAV 1092
Query: 365 GGG----EMARAPPPPRPCLRKEVFPLGGVGASPSLTTSCSSTASTSFSEPAEPRLGSTK 420
G ++A P P+ + V P+ ST T +P + +
Sbjct: 1093 FSGNTSPKVAVVNPQPQQWSKMSV----KKAPPPTRPKRNDSTRLTQAEISEQPTMATVV 1148
Query: 421 GKEPRASKDQVLSEP----------ETKTMGKVSRFRIRRTPARPQLNLTPMGLPRP 467
+ P + K + +P + K++ + R + A P + M LP P
Sbjct: 1149 PQVPTSPKSSLSVQPGFLADLNRTLQRKSITRHGSLSSRMSRAEPTATMDDMALPPP 1205
Score = 55.1 bits (131), Expect = 2e-07
Identities = 61/231 (26%), Positives = 84/231 (36%), Gaps = 26/231 (11%)
Query: 175 PNFIIPAQRAEPMRIVRQPTPPPGDLEPPFQPSALPADPLESPPTAPDPALELPSTPPPS 234
P + P ++P + P PPP PP P P PL S +AP P S
Sbjct: 613 PKIVTPYTASQPSPPLPPPPPPPP---PPPPPPPPPPPPLPS-QSAPSAGSAAPMFVKYS 668
Query: 235 SLLRPRLSPWGLAPLFRSVRSKL---ESFADIFLTPNKTPQPPPPSPPMKLELKIAISEA 291
++ R + + LF+ + +S L P PPPP PP A+++
Sbjct: 669 TITRLQNASQHSGALFKPPTPPVMQSQSVKPQILVPPNGVVPPPPPPPPPPTPGSAMAQL 728
Query: 292 EQSGAAEGTASVSPRPPIRQWRTQDHNTPALLPKPSLGRSYSCPDLGPPGPGTCTWPP-A 350
+ + A S PP + H T P P PP P PP A
Sbjct: 729 KPAPCAPSLPQFSAPPPPLKIHQVQHITQVAPPTPP-----------PPPPIPAPLPPQA 777
Query: 351 PPQP--SRPRP-RRHTVGGGEMARAPPPPR----PCLRKEVFPLGGVGASP 394
PP+P + P P TV APP P P ++ FP + SP
Sbjct: 778 PPKPLVTIPAPTSTKTVAPVVTQAAPPTPTPPVPPAKKQPAFPASYIPPSP 828
Score = 52.8 bits (125), Expect = 9e-07
Identities = 74/322 (22%), Positives = 108/322 (33%), Gaps = 36/322 (11%)
Query: 163 PRPPAEGFIDETPNFIIPAQRAEPMRIVRQPTPPPGDLEPPFQPSALPADPLESPPTAPD 222
P PP P ++P P P P PG +P+ P P +AP
Sbjct: 687 PTPPVMQSQSVKPQILVPPNGVVPPPPPPPPPPTPGSAMAQLKPA--PCAPSLPQFSAPP 744
Query: 223 PALEL----------PSTPPP----SSLLRPRLSPWGLAPLFRSVRSKLESFADIFLTPN 268
P L++ P TPPP + L P+ P L + +K + A + +T
Sbjct: 745 PPLKIHQVQHITQVAPPTPPPPPPIPAPLPPQAPPKPLVTIPAPTSTK--TVAPV-VTQA 801
Query: 269 KTPQPPPPSPPMKLELKIAISEAEQSGAAEGTASVSPRPPIRQWRTQDHNTPALLPKPSL 328
P P PP PP K + S S P P +Q L P PS+
Sbjct: 802 APPTPTPPVPPAKKQPAFPASYIPPSPPTPPVPVPPPTLPKQQSFCAKPPPSPLSPVPSV 861
Query: 329 GRSYSCPDLGPPGPGTCTWPPAPPQP------------SRPRPRRHTVGGGEMARAPPPP 376
+ + PP P P P P ++P+ + ++ PPPP
Sbjct: 862 VKQIASQFPPPPTPPAMESQPLKPVPANVAPQSPPAVKAKPKWQPSSIPVPSPDFPPPPP 921
Query: 377 RPCLRKEVFPLGGVGASPSLTTSCSSTASTSFSEPAEPRLGSTKGKEPRASKDQVLSEPE 436
L VFP P+ TAS + + P ++K P K P+
Sbjct: 922 ESSL---VFPPPPPSPVPAPPPPPPPTASPTPDKSGSPGKKTSKTSSPGGKKPP--PTPQ 976
Query: 437 TKTMGKVSRFRIRRTPARPQLN 458
+ K S P RP ++
Sbjct: 977 RNSSIKSSSGAEHPEPKRPSVD 998
Score = 35.0 bits (79), Expect = 0.19
Identities = 32/123 (26%), Positives = 42/123 (34%), Gaps = 31/123 (25%)
Query: 320 PALLPKPSLGRSYSCPDLGPPGPGTCTWPPAPPQPSRPRPRRHTVGGGEMARAPPPPRPC 379
P L P+P + Y+ PP P PP PP P PPPP P
Sbjct: 607 PPLSPQPKIVTPYTASQPSPPLPPPPPPPPPPPPP------------------PPPPPPP 648
Query: 380 LRKEVFPLGGVGASPSLTTS-------CSSTASTSFSEPAEPRLGSTKGKEPRASKDQVL 432
L + P G A + S S + F P P + S ++ K Q+L
Sbjct: 649 LPSQSAPSAGSAAPMFVKYSTITRLQNASQHSGALFKPPTPPVMQS------QSVKPQIL 702
Query: 433 SEP 435
P
Sbjct: 703 VPP 705
>gi|239754327 PREDICTED: chromosome 6 open reading frame 132 [Homo
sapiens]
Length = 1188
Score = 65.1 bits (157), Expect = 2e-10
Identities = 82/310 (26%), Positives = 107/310 (34%), Gaps = 69/310 (22%)
Query: 135 PGPEEGPSQKVDRAPQPTLVVMLEDIASPRPPAEGFIDETPNFIIP----AQRAEPMRIV 190
PGP GP Q + P + + A P PP P+ P + P +
Sbjct: 144 PGPAPGPPQDISEPPGGSPLPSPPSTAPPPPPLLLEPPPPPSMAPPPPPVLEALSPPHTL 203
Query: 191 RQPT-PPPGDLEPPFQPSALPADPLESPPTAPDPALELPSTPPPSSLLRPRLSPWGLAPL 249
P+ P P D PP P A A P PP P PA P++P + RL P G
Sbjct: 204 SSPSIPTPPDFIPPAPPLAFLAPP---PPPVPAPAPPAPASP---HTVGTRLFPPGGVTK 257
Query: 250 FRS----------------VRSKLESFADIFLTPNKTP--------QPPPPSPPMKLELK 285
++S RS E L PN P + PPP+P +
Sbjct: 258 WKSDVALNGRQAEATRASPPRSPAEPKGSA-LGPNPEPHLTFPRSFKVPPPTPVRTSSIP 316
Query: 286 IAISE---AEQSGAAEGTASVSPRPPIRQWRTQDHNTPALLPKPS--------------L 328
+ ++ ++ GA + S P PP R P P+P L
Sbjct: 317 VQEAQEAPRKEEGATKKAPSRLPLPPSFHIRPASQVYPDRAPEPDCPGELKATAPASPRL 376
Query: 329 GRSYSCPD--LGPPGPGTCTWPPAPPQPSRPRPRRHTVGGGEMARAPP--PPRPCLRKEV 384
G+S S D G P P PPAPP P P PP PP PC +K
Sbjct: 377 GQSQSQADERAGTPPPAPPLPPPAPPLPPPAPP------------LPPAAPPLPCAQKAA 424
Query: 385 FPLGGVGASP 394
P G +P
Sbjct: 425 HPPAGFTKTP 434
Score = 52.8 bits (125), Expect = 9e-07
Identities = 96/413 (23%), Positives = 141/413 (34%), Gaps = 80/413 (19%)
Query: 90 PPASPPRQAGWSSQARPPDPLCLCRE---PLSRIHRTSSTLRRRSRTTPGPEEGPSQKV- 145
PP SP G + P L R P RTSS + ++ P EEG ++K
Sbjct: 276 PPRSPAEPKGSALGPNPEPHLTFPRSFKVPPPTPVRTSSIPVQEAQEAPRKEEGATKKAP 335
Query: 146 DRAPQPTL-----VVMLEDIASPRPPAEGFIDETPNFIIPAQRAEPMRIVRQPTPPPG-D 199
R P P + +P P G + T +++ R TPPP
Sbjct: 336 SRLPLPPSFHIRPASQVYPDRAPEPDCPGELKATAPASPRLGQSQSQADERAGTPPPAPP 395
Query: 200 LEPPFQPSALPADPLESPPTAPD-PALELPSTPPPSSLLRPRLSPWGLAPLFRSVRSKLE 258
L PP P PA PL PP AP P + + PP P+ S
Sbjct: 396 LPPPAPPLPPPAPPL--PPAAPPLPCAQKAAHPPAGFTKTPKSS---------------- 437
Query: 259 SFADIFLTPNKTPQPPPPSP-------------PMKLELKIAISEAEQSGAAEGTASVSP 305
+P P+P PPSP P ++E A G+ +S
Sbjct: 438 -------SPALKPKPNPPSPENTASSAPVDWRDPSQMEKLRNELAAYLCGSRREDRFLSH 490
Query: 306 RPPIRQWRTQDHNTPALLPKPSLGRSYSCPDLGPPGPGTCTWPPAPPQPSRPRPRRHTVG 365
RP P + P+ G+ GP P T P + + P ++G
Sbjct: 491 RP-----------GPTVAPQSKEGKK------GPRLPEKETLLSLPAKDTPPGVPEKSLG 533
Query: 366 GGEMARAPPPPRPCLRKEVFPLGGVGASPS---LTTSCSSTASTSFSEPAEPRLGSTKGK 422
G + P L V + +PS + + S++ + A+P +GS K
Sbjct: 534 GSSLTETEAAPSLTL-PSVDYIPQDSPTPSVRQIRNELEARLSSAAEKEAKPSIGSLPPK 592
Query: 423 EPR---------ASKDQVLSEPETKTMGKVSRFRIRRTPARPQLNLTPMGLPR 466
PR + D LS+P K + S + T +P+ L P P+
Sbjct: 593 -PRLEGGRICENGADDDKLSKPVAKNLPPQSTTLLPTTSLQPKAMLGPAIPPK 644
Score = 35.4 bits (80), Expect = 0.15
Identities = 93/417 (22%), Positives = 132/417 (31%), Gaps = 82/417 (19%)
Query: 4 PGDSSPPGQPRLCRQPLTRALWGARSPKRPRLQLPGAP-SPLEKASRRVLAVVLEDVMAV 62
P D P Q R L L G+R R PG +P K ++
Sbjct: 458 PVDWRDPSQMEKLRNELAAYLCGSRREDRFLSHRPGPTVAPQSKEGKKG----------- 506
Query: 63 HMVPVVPSKQTSIPQHHSYHQDPVHRQPPASPPRQAGWSSQARPPDPLCLCREPLSRIHR 122
P +P K+T + P PP P + G SS L + I +
Sbjct: 507 ---PRLPEKETLLSL-------PAKDTPPGVPEKSLGGSSLTETEAAPSLTLPSVDYIPQ 556
Query: 123 TSST---------LRRRSRTTPGPEEGPSQKVDRAPQPTLVVM------LEDIASPRPPA 167
S T L R + E PS P+P L +D +P A
Sbjct: 557 DSPTPSVRQIRNELEARLSSAAEKEAKPSIG-SLPPKPRLEGGRICENGADDDKLSKPVA 615
Query: 168 EGFIDETPNFIIPAQRAEPMRIVRQPTPPPGDLEPPFQPSAL--PADPLESPPTAPDPAL 225
+ ++ ++P +P ++ PP EP P A PA P P PA
Sbjct: 616 KNLPPQSTT-LLPTTSLQPKAMLGPAIPPKATPEPAIPPKATLWPATP---PKATLGPAT 671
Query: 226 ELPSTPPPSSLLRPRLSPWGLAPLFRSVRSKLESFADIFLTPNKTPQPPPPSPPMKLELK 285
L +T P++ L+ P S + L + + + P P E+
Sbjct: 672 PLKATSGPTTPLKAT-----SGPAIASTATTLPTTTSQLMAEKDSGPAGQPEKPASQEV- 725
Query: 286 IAISEAEQSGAAEGTASVSPRPPIRQWRTQDHNTPALLP---------KP-----SLGRS 331
EG+ S + R P + R+ P P KP SL R
Sbjct: 726 ----STPSQARGEGSPSEATRLPTQGARSSAAFPPKTSPGGGEVPCLYKPHCHQSSLSRE 781
Query: 332 YS--CPDL---GPPGPGTCT-------WPPAPPQPSRPRPR--RHTVGGGEMARAPP 374
+ P L G GPG P PP ++P RH V G + R P
Sbjct: 782 VAVVMPTLARGGAAGPGEPVEVKEPPGLPAKPPASAQPTDELLRHPVTGEVVERGSP 838
>gi|239748855 PREDICTED: chromosome 6 open reading frame 132 [Homo
sapiens]
Length = 1188
Score = 65.1 bits (157), Expect = 2e-10
Identities = 82/310 (26%), Positives = 107/310 (34%), Gaps = 69/310 (22%)
Query: 135 PGPEEGPSQKVDRAPQPTLVVMLEDIASPRPPAEGFIDETPNFIIP----AQRAEPMRIV 190
PGP GP Q + P + + A P PP P+ P + P +
Sbjct: 144 PGPAPGPPQDISEPPGGSPLPSPPSTAPPPPPLLLEPPPPPSMAPPPPPVLEALSPPHTL 203
Query: 191 RQPT-PPPGDLEPPFQPSALPADPLESPPTAPDPALELPSTPPPSSLLRPRLSPWGLAPL 249
P+ P P D PP P A A P PP P PA P++P + RL P G
Sbjct: 204 SSPSIPTPPDFIPPAPPLAFLAPP---PPPVPAPAPPAPASP---HTVGTRLFPPGGVTK 257
Query: 250 FRS----------------VRSKLESFADIFLTPNKTP--------QPPPPSPPMKLELK 285
++S RS E L PN P + PPP+P +
Sbjct: 258 WKSDVALNGRQAEATRASPPRSPAEPKGSA-LGPNPEPHLTFPRSFKVPPPTPVRTSSIP 316
Query: 286 IAISE---AEQSGAAEGTASVSPRPPIRQWRTQDHNTPALLPKPS--------------L 328
+ ++ ++ GA + S P PP R P P+P L
Sbjct: 317 VQEAQEAPRKEEGATKKAPSRLPLPPSFHIRPASQVYPDRAPEPDCPGELKATAPASPRL 376
Query: 329 GRSYSCPD--LGPPGPGTCTWPPAPPQPSRPRPRRHTVGGGEMARAPP--PPRPCLRKEV 384
G+S S D G P P PPAPP P P PP PP PC +K
Sbjct: 377 GQSQSQADERAGTPPPAPPLPPPAPPLPPPAPP------------LPPAAPPLPCAQKAA 424
Query: 385 FPLGGVGASP 394
P G +P
Sbjct: 425 HPPAGFTKTP 434
Score = 52.8 bits (125), Expect = 9e-07
Identities = 96/413 (23%), Positives = 141/413 (34%), Gaps = 80/413 (19%)
Query: 90 PPASPPRQAGWSSQARPPDPLCLCRE---PLSRIHRTSSTLRRRSRTTPGPEEGPSQKV- 145
PP SP G + P L R P RTSS + ++ P EEG ++K
Sbjct: 276 PPRSPAEPKGSALGPNPEPHLTFPRSFKVPPPTPVRTSSIPVQEAQEAPRKEEGATKKAP 335
Query: 146 DRAPQPTL-----VVMLEDIASPRPPAEGFIDETPNFIIPAQRAEPMRIVRQPTPPPG-D 199
R P P + +P P G + T +++ R TPPP
Sbjct: 336 SRLPLPPSFHIRPASQVYPDRAPEPDCPGELKATAPASPRLGQSQSQADERAGTPPPAPP 395
Query: 200 LEPPFQPSALPADPLESPPTAPD-PALELPSTPPPSSLLRPRLSPWGLAPLFRSVRSKLE 258
L PP P PA PL PP AP P + + PP P+ S
Sbjct: 396 LPPPAPPLPPPAPPL--PPAAPPLPCAQKAAHPPAGFTKTPKSS---------------- 437
Query: 259 SFADIFLTPNKTPQPPPPSP-------------PMKLELKIAISEAEQSGAAEGTASVSP 305
+P P+P PPSP P ++E A G+ +S
Sbjct: 438 -------SPALKPKPNPPSPENTASSAPVDWRDPSQMEKLRNELAAYLCGSRREDRFLSH 490
Query: 306 RPPIRQWRTQDHNTPALLPKPSLGRSYSCPDLGPPGPGTCTWPPAPPQPSRPRPRRHTVG 365
RP P + P+ G+ GP P T P + + P ++G
Sbjct: 491 RP-----------GPTVAPQSKEGKK------GPRLPEKETLLSLPAKDTPPGVPEKSLG 533
Query: 366 GGEMARAPPPPRPCLRKEVFPLGGVGASPS---LTTSCSSTASTSFSEPAEPRLGSTKGK 422
G + P L V + +PS + + S++ + A+P +GS K
Sbjct: 534 GSSLTETEAAPSLTL-PSVDYIPQDSPTPSVRQIRNELEARLSSAAEKEAKPSIGSLPPK 592
Query: 423 EPR---------ASKDQVLSEPETKTMGKVSRFRIRRTPARPQLNLTPMGLPR 466
PR + D LS+P K + S + T +P+ L P P+
Sbjct: 593 -PRLEGGRICENGADDDKLSKPVAKNLPPQSTTLLPTTSLQPKAMLGPAIPPK 644
Score = 35.4 bits (80), Expect = 0.15
Identities = 93/417 (22%), Positives = 132/417 (31%), Gaps = 82/417 (19%)
Query: 4 PGDSSPPGQPRLCRQPLTRALWGARSPKRPRLQLPGAP-SPLEKASRRVLAVVLEDVMAV 62
P D P Q R L L G+R R PG +P K ++
Sbjct: 458 PVDWRDPSQMEKLRNELAAYLCGSRREDRFLSHRPGPTVAPQSKEGKKG----------- 506
Query: 63 HMVPVVPSKQTSIPQHHSYHQDPVHRQPPASPPRQAGWSSQARPPDPLCLCREPLSRIHR 122
P +P K+T + P PP P + G SS L + I +
Sbjct: 507 ---PRLPEKETLLSL-------PAKDTPPGVPEKSLGGSSLTETEAAPSLTLPSVDYIPQ 556
Query: 123 TSST---------LRRRSRTTPGPEEGPSQKVDRAPQPTLVVM------LEDIASPRPPA 167
S T L R + E PS P+P L +D +P A
Sbjct: 557 DSPTPSVRQIRNELEARLSSAAEKEAKPSIG-SLPPKPRLEGGRICENGADDDKLSKPVA 615
Query: 168 EGFIDETPNFIIPAQRAEPMRIVRQPTPPPGDLEPPFQPSAL--PADPLESPPTAPDPAL 225
+ ++ ++P +P ++ PP EP P A PA P P PA
Sbjct: 616 KNLPPQSTT-LLPTTSLQPKAMLGPAIPPKATPEPAIPPKATLWPATP---PKATLGPAT 671
Query: 226 ELPSTPPPSSLLRPRLSPWGLAPLFRSVRSKLESFADIFLTPNKTPQPPPPSPPMKLELK 285
L +T P++ L+ P S + L + + + P P E+
Sbjct: 672 PLKATSGPTTPLKAT-----SGPAIASTATTLPTTTSQLMAEKDSGPAGQPEKPASQEV- 725
Query: 286 IAISEAEQSGAAEGTASVSPRPPIRQWRTQDHNTPALLP---------KP-----SLGRS 331
EG+ S + R P + R+ P P KP SL R
Sbjct: 726 ----STPSQARGEGSPSEATRLPTQGARSSAAFPPKTSPGGGEVPCLYKPHCHQSSLSRE 781
Query: 332 YS--CPDL---GPPGPGTCT-------WPPAPPQPSRPRPR--RHTVGGGEMARAPP 374
+ P L G GPG P PP ++P RH V G + R P
Sbjct: 782 VAVVMPTLARGGAAGPGEPVEVKEPPGLPAKPPASAQPTDELLRHPVTGEVVERGSP 838
>gi|239742884 PREDICTED: hypothetical protein LOC647024 [Homo
sapiens]
Length = 1188
Score = 65.1 bits (157), Expect = 2e-10
Identities = 82/310 (26%), Positives = 107/310 (34%), Gaps = 69/310 (22%)
Query: 135 PGPEEGPSQKVDRAPQPTLVVMLEDIASPRPPAEGFIDETPNFIIP----AQRAEPMRIV 190
PGP GP Q + P + + A P PP P+ P + P +
Sbjct: 144 PGPAPGPPQDISEPPGGSPLPSPPSTAPPPPPLLLEPPPPPSMAPPPPPVLEALSPPHTL 203
Query: 191 RQPT-PPPGDLEPPFQPSALPADPLESPPTAPDPALELPSTPPPSSLLRPRLSPWGLAPL 249
P+ P P D PP P A A P PP P PA P++P + RL P G
Sbjct: 204 SSPSIPTPPDFIPPAPPLAFLAPP---PPPVPAPAPPAPASP---HTVGTRLFPPGGVTK 257
Query: 250 FRS----------------VRSKLESFADIFLTPNKTP--------QPPPPSPPMKLELK 285
++S RS E L PN P + PPP+P +
Sbjct: 258 WKSDVALNGRQAEATRASPPRSPAEPKGSA-LGPNPEPHLTFPRSFKVPPPTPVRTSSIP 316
Query: 286 IAISE---AEQSGAAEGTASVSPRPPIRQWRTQDHNTPALLPKPS--------------L 328
+ ++ ++ GA + S P PP R P P+P L
Sbjct: 317 VQEAQEAPRKEEGATKKAPSRLPLPPSFHIRPASQVYPDRAPEPDCPGELKATAPASPRL 376
Query: 329 GRSYSCPD--LGPPGPGTCTWPPAPPQPSRPRPRRHTVGGGEMARAPP--PPRPCLRKEV 384
G+S S D G P P PPAPP P P PP PP PC +K
Sbjct: 377 GQSQSQADERAGTPPPAPPLPPPAPPLPPPAPP------------LPPAAPPLPCAQKAA 424
Query: 385 FPLGGVGASP 394
P G +P
Sbjct: 425 HPPAGFTKTP 434
Score = 52.8 bits (125), Expect = 9e-07
Identities = 96/413 (23%), Positives = 141/413 (34%), Gaps = 80/413 (19%)
Query: 90 PPASPPRQAGWSSQARPPDPLCLCRE---PLSRIHRTSSTLRRRSRTTPGPEEGPSQKV- 145
PP SP G + P L R P RTSS + ++ P EEG ++K
Sbjct: 276 PPRSPAEPKGSALGPNPEPHLTFPRSFKVPPPTPVRTSSIPVQEAQEAPRKEEGATKKAP 335
Query: 146 DRAPQPTL-----VVMLEDIASPRPPAEGFIDETPNFIIPAQRAEPMRIVRQPTPPPG-D 199
R P P + +P P G + T +++ R TPPP
Sbjct: 336 SRLPLPPSFHIRPASQVYPDRAPEPDCPGELKATAPASPRLGQSQSQADERAGTPPPAPP 395
Query: 200 LEPPFQPSALPADPLESPPTAPD-PALELPSTPPPSSLLRPRLSPWGLAPLFRSVRSKLE 258
L PP P PA PL PP AP P + + PP P+ S
Sbjct: 396 LPPPAPPLPPPAPPL--PPAAPPLPCAQKAAHPPAGFTKTPKSS---------------- 437
Query: 259 SFADIFLTPNKTPQPPPPSP-------------PMKLELKIAISEAEQSGAAEGTASVSP 305
+P P+P PPSP P ++E A G+ +S
Sbjct: 438 -------SPALKPKPNPPSPENTASSAPVDWRDPSQMEKLRNELAAYLCGSRREDRFLSH 490
Query: 306 RPPIRQWRTQDHNTPALLPKPSLGRSYSCPDLGPPGPGTCTWPPAPPQPSRPRPRRHTVG 365
RP P + P+ G+ GP P T P + + P ++G
Sbjct: 491 RP-----------GPTVAPQSKEGKK------GPRLPEKETLLSLPAKDTPPGVPEKSLG 533
Query: 366 GGEMARAPPPPRPCLRKEVFPLGGVGASPS---LTTSCSSTASTSFSEPAEPRLGSTKGK 422
G + P L V + +PS + + S++ + A+P +GS K
Sbjct: 534 GSSLTETEAAPSLTL-PSVDYIPQDSPTPSVRQIRNELEARLSSAAEKEAKPSIGSLPPK 592
Query: 423 EPR---------ASKDQVLSEPETKTMGKVSRFRIRRTPARPQLNLTPMGLPR 466
PR + D LS+P K + S + T +P+ L P P+
Sbjct: 593 -PRLEGGRICENGADDDKLSKPVAKNLPPQSTTLLPTTSLQPKAMLGPAIPPK 644
Score = 35.4 bits (80), Expect = 0.15
Identities = 93/417 (22%), Positives = 132/417 (31%), Gaps = 82/417 (19%)
Query: 4 PGDSSPPGQPRLCRQPLTRALWGARSPKRPRLQLPGAP-SPLEKASRRVLAVVLEDVMAV 62
P D P Q R L L G+R R PG +P K ++
Sbjct: 458 PVDWRDPSQMEKLRNELAAYLCGSRREDRFLSHRPGPTVAPQSKEGKKG----------- 506
Query: 63 HMVPVVPSKQTSIPQHHSYHQDPVHRQPPASPPRQAGWSSQARPPDPLCLCREPLSRIHR 122
P +P K+T + P PP P + G SS L + I +
Sbjct: 507 ---PRLPEKETLLSL-------PAKDTPPGVPEKSLGGSSLTETEAAPSLTLPSVDYIPQ 556
Query: 123 TSST---------LRRRSRTTPGPEEGPSQKVDRAPQPTLVVM------LEDIASPRPPA 167
S T L R + E PS P+P L +D +P A
Sbjct: 557 DSPTPSVRQIRNELEARLSSAAEKEAKPSIG-SLPPKPRLEGGRICENGADDDKLSKPVA 615
Query: 168 EGFIDETPNFIIPAQRAEPMRIVRQPTPPPGDLEPPFQPSAL--PADPLESPPTAPDPAL 225
+ ++ ++P +P ++ PP EP P A PA P P PA
Sbjct: 616 KNLPPQSTT-LLPTTSLQPKAMLGPAIPPKATPEPAIPPKATLWPATP---PKATLGPAT 671
Query: 226 ELPSTPPPSSLLRPRLSPWGLAPLFRSVRSKLESFADIFLTPNKTPQPPPPSPPMKLELK 285
L +T P++ L+ P S + L + + + P P E+
Sbjct: 672 PLKATSGPTTPLKAT-----SGPAIASTATTLPTTTSQLMAEKDSGPAGQPEKPASQEV- 725
Query: 286 IAISEAEQSGAAEGTASVSPRPPIRQWRTQDHNTPALLP---------KP-----SLGRS 331
EG+ S + R P + R+ P P KP SL R
Sbjct: 726 ----STPSQARGEGSPSEATRLPTQGARSSAAFPPKTSPGGGEVPCLYKPHCHQSSLSRE 781
Query: 332 YS--CPDL---GPPGPGTCT-------WPPAPPQPSRPRPR--RHTVGGGEMARAPP 374
+ P L G GPG P PP ++P RH V G + R P
Sbjct: 782 VAVVMPTLARGGAAGPGEPVEVKEPPGLPAKPPASAQPTDELLRHPVTGEVVERGSP 838
>gi|150170670 piccolo isoform 2 [Homo sapiens]
Length = 4935
Score = 65.1 bits (157), Expect = 2e-10
Identities = 98/411 (23%), Positives = 148/411 (36%), Gaps = 59/411 (14%)
Query: 85 PVHRQPPASPPRQAGWSSQARPPDPLCLCREPLSRIHRTSSTLRRRSRTTPGPEEGPSQ- 143
P+ +QPP P+Q G DPL P S + ++ + T P +GP+Q
Sbjct: 210 PLQQQPPKPIPKQQGPGR-----DPLQQDGTPKSISSQQPEKIKSQPPGTGKPIQGPTQT 264
Query: 144 -KVDRAPQPTLVVMLEDIASPRPPAEGFI-DETPNFIIPAQRAEPMRIVRQPTP------ 195
+ D A P + D + P+ + E+ +P+ P ++QPTP
Sbjct: 265 PQTDHAKLP----LQRDASRPQTKQADIVRGESVKPSLPSPSKPP---IQQPTPGKPPAQ 317
Query: 196 -------PPGDLEPPFQPSALPADPLESPPTAPDPALELPSTPPPSSLLRPRLSPWGLAP 248
PG +PP QPS L + P T P +T PP+ L P P A
Sbjct: 318 QPGHEKSQPGPAKPPAQPSGLTKPLAQQPGTVKPPVQPPGTTKPPAQPLGPAKPP---AQ 374
Query: 249 LFRSVRSKLESFADIFLTP----NKTP-QPPPPSPPMKLELKIAISEAEQSGAAEGTASV 303
S + E L KTP Q P P+ P ++ A+Q G +
Sbjct: 375 QTGSEKPSSEQPGPKALAQPPGVGKTPAQQPGPAKPPTQQVGTPKPLAQQPGLQSPAKAP 434
Query: 304 SP-RPPIRQWRTQDHNTPALLPKPSLG-RSYSCPDLGPPGPGTCTWPPAPPQPSRPRPRR 361
P + P++Q P +P G S GP P + PA P P +P P +
Sbjct: 435 GPTKTPVQQ------PGPGKIPAQQAGPGKTSAQQTGPTKPPSQLPGPAKPPPQQPGPAK 488
Query: 362 HTVGGGEMARAPPPPRPCLRKEVFPLGGVGASPSLTTSCS--STASTSFSEPAEPRLGST 419
PPP +P K G P + S ++P + GS
Sbjct: 489 -----------PPPQQPGSAKPPSQQPGSTKPPPQQPGPAKPSPQQPGSTKPPSQQPGSA 537
Query: 420 KGKEPRASKDQVLSEPETKTMGKVSRFRIRRTP-ARPQLNLTP-MGLPRPI 468
K + S + ++ TK + + + + P P P GLP+ I
Sbjct: 538 KPSAQQPSPAKPSAQQSTKPVSQTGSGKPLQPPTVSPSAKQPPSQGLPKTI 588
Score = 62.8 bits (151), Expect = 9e-10
Identities = 100/442 (22%), Positives = 139/442 (31%), Gaps = 86/442 (19%)
Query: 4 PGDSSPPGQPRLCRQPLTRALWGARSPKRPRLQLPGAPSPLEKASRRVLAVVLEDVMAVH 63
PG + PP QP +PL Q PG P
Sbjct: 326 PGPAKPPAQPSGLTKPLA--------------QQPGTVKP-------------------- 351
Query: 64 MVPVVPSKQTSIPQHHSYHQDPVHRQPPASPPRQAGWSSQ--ARPPDPLCLCREPLSRIH 121
PV P T + P PA PP Q S + + P P L + P
Sbjct: 352 --PVQPPGTT---------KPPAQPLGPAKPPAQQTGSEKPSSEQPGPKALAQPP----- 395
Query: 122 RTSSTLRRRSRTTPGPEEGPSQKVDRAPQPTLVVMLEDIASPRPPAEGFIDETPNFIIPA 181
+ + PGP + P+Q+V L+ A P + + + IPA
Sbjct: 396 ----GVGKTPAQQPGPAKPPTQQVGTPKPLAQQPGLQSPAKAPGPTKTPVQQPGPGKIPA 451
Query: 182 QRAEPMRIVRQ---PTPPPGDLEPPFQPSALPADPLESPPTAPDPALELPSTPPPSSLLR 238
Q+A P + Q PT PP L P +P P + PP P A P + P S
Sbjct: 452 QQAGPGKTSAQQTGPTKPPSQLPGPAKPPPQQPGPAKPPPQQPGSA--KPPSQQPGSTKP 509
Query: 239 PRLSPWGLAPLFRSVRSKLESFADIFLTPNKTPQPPPPSPPMKLELKIAISEAEQSGAAE 298
P P P + S QP P P + K
Sbjct: 510 PPQQPGPAKPSPQQPGSTKPPSQQPGSAKPSAQQPSPAKPSAQQSTKPVSQTGSGKPLQP 569
Query: 299 GTASVSPRPPIRQWRTQD-----HNTPALLPKPSLGRSYSCPDLGPPGPGTCTWPPAPPQ 353
T S S + P Q + + T LL P +C + C + P P
Sbjct: 570 PTVSPSAKQPPSQGLPKTICPLCNTTELLLHVPEKANFNTCTECQTTVCSLCGFNPNPHL 629
Query: 354 PSRP-----RPRRHTVGGGEMARAPPPPRPCLRKEVFPLGGVGASPSLTTSCSSTAS--- 405
+ GG++A P P+P L+ +P TTS S +S
Sbjct: 630 TEVKEWLCLNCQMKRALGGDLAPVPSSPQPKLK----------TAPVTTTSAVSKSSPQP 679
Query: 406 --TSFSEPAEPRLGSTKGKEPR 425
TS + A P+ +K EP+
Sbjct: 680 QQTSPKKDAAPKQDLSKAPEPK 701
Score = 49.7 bits (117), Expect = 8e-06
Identities = 52/180 (28%), Positives = 73/180 (40%), Gaps = 25/180 (13%)
Query: 158 EDIASPRPPAEGFIDETPNFIIPAQRAEPMRIVRQPTPPPGDLEPPFQPSALPADPLESP 217
E AS P + P P R+ + I QP PPP PP P P
Sbjct: 2370 EKPASQLPSGSPSVSSLPAKPRPFFRSSSLDISAQPPPPPPPPPPPPPP----------P 2419
Query: 218 PTAPDPALELPSTPPPSSLLRPRL---SPWGLA-PLFRSVRSKLESFADIFLTPNKTP-- 271
P P P L P++P P+ L + +L SP A PLF +V + LE+ A L N P
Sbjct: 2420 PPPPPPPLPPPTSPKPTILPKKKLTVASPVTTATPLFDAV-TTLETTA--VLRSNGLPVT 2476
Query: 272 ----QPPPPSPPMKLELKIAISEAEQSGAAEGTASVSPRPPIRQWRTQDHNTPALLPKPS 327
PPP PP + + + ++ ++P+P I Q T + PKP+
Sbjct: 2477 RICTTAPPPVPPKPSSIPSGLVFTHRPEPSK--PPIAPKPVIPQLPTTTQKPTDIHPKPT 2534
Score = 43.5 bits (101), Expect = 5e-04
Identities = 63/251 (25%), Positives = 87/251 (34%), Gaps = 51/251 (20%)
Query: 223 PALELPSTPPPSSLL--RPRLSPWGLAPLFRSVRSKLESFADIFLTPNKTPQPPPPSPPM 280
PA +LPS P S L +PR P FRS S DI P P PPPP PP
Sbjct: 2372 PASQLPSGSPSVSSLPAKPR-------PFFRS------SSLDISAQPPPPPPPPPPPPP- 2417
Query: 281 KLELKIAISEAEQSGAAEGTASVSPRPPIRQWRTQDHNTPALLPKP------SLGRSYSC 334
SP+P I + +P P +L +
Sbjct: 2418 ---------PPPPPPPPPLPPPTSPKPTILPKKKLTVASPVTTATPLFDAVTTLETTAVL 2468
Query: 335 PDLGPPGPGTCTW--PPAPPQPSRPRPRRHTVGGGEMARAPPPPRPCLRK---------E 383
G P CT PP PP+PS E ++ P P+P + + +
Sbjct: 2469 RSNGLPVTRICTTAPPPVPPKPSSIPSGLVFTHRPEPSKPPIAPKPVIPQLPTTTQKPTD 2528
Query: 384 VFPLG-GVGASPSLTTSCSSTASTSFSEPAEPRLGSTKGKEPRASKD--------QVLSE 434
+ P G+ + S+T + ++A P P + PR SK + SE
Sbjct: 2529 IHPKPTGLSLTSSMTLNLVTSADYKLPSPTSPLSPHSNKSSPRFSKSLTETYVVITLPSE 2588
Query: 435 PETKTMGKVSR 445
P T T S+
Sbjct: 2589 PGTPTDSSASQ 2599
Score = 39.7 bits (91), Expect = 0.008
Identities = 84/409 (20%), Positives = 135/409 (33%), Gaps = 97/409 (23%)
Query: 70 SKQTSIPQHHSYHQDPVHRQPPASPPRQAGWSSQARPPDPLCLCREPLSRIHRTSSTLRR 129
SK + PQ S +D +Q + P P P L ++P +H + S +
Sbjct: 673 SKSSPQPQQTSPKKDAAPKQDLSKAPE---------PKKPPPLVKQPT--LHGSPSAKAK 721
Query: 130 R-----SRTTPGPEEGPS--QKVDRAP-------QPTLVVMLEDIAS----------PRP 165
+ S + P P + PS + D+AP QP +V D+ S P
Sbjct: 722 QPPEADSLSKPAPPKEPSVPSEQDKAPVADDKPKQPKMVKPTTDLVSSSSATTKPDIPSS 781
Query: 166 PAEGFIDETPNFIIPAQRAEPMRIVRQPTPPPGDLEPPFQPSALPADPLESPPTAPDPAL 225
+ +E + A+P Q PP G+ PF A+P +S
Sbjct: 782 KVQSQAEEKTTPPLKTDSAKPS----QSFPPTGEKVSPFDSKAIPRPASDS--------- 828
Query: 226 ELPSTPPPSSLLR--PRLSPWGLAPLFRSVRSKLESFADIFLTPNKTPQPPPPSPPMKLE 283
++ S P PSS + ++ P + ++K+ D P +P PP P P
Sbjct: 829 KIISHPGPSSESKGQKQVDPVQKKEEPKKAQTKMSPKPDAKPMPKGSPTPPGPRP----- 883
Query: 284 LKIAISEAEQSGAAEGTASVSPRPPIRQWRTQDHNTPALLPKPSLGRSYSCPDLGPPGP- 342
+G T SP+P + R +LG P P P
Sbjct: 884 ---------TAGQTVPTPQQSPKPQEQSRRF----------SLNLGSITDAPKSQPTTPQ 924
Query: 343 ----------GTCTWPPAP---PQPSRPRPRRHTVGGGEMARAPPPPRPCLRKEVFPLGG 389
G + A +P P + G M +AP P +P +
Sbjct: 925 ETVTGKLFGFGASIFSQASNLISTAGQPGPHSQSGPGAPMKQAPAPSQPPTSQ------- 977
Query: 390 VGASPSLTTSCSSTASTSFSEPAEPRLGSTKGKEPRASKDQVLSEPETK 438
P T + S E + + + EP+A + + ET+
Sbjct: 978 --GPPKSTGQAPPAPAKSIPVKKETKAPAAEKLEPKAEQAPTVKRTETE 1024
Score = 34.3 bits (77), Expect = 0.33
Identities = 88/388 (22%), Positives = 132/388 (34%), Gaps = 65/388 (16%)
Query: 2 DLPGDSSPPGQPRLCRQPLTRALWGARSPKRPRLQLPGAPSPLEKASRRVLAVVLEDVMA 61
DL P P L +QP A++ + P P+P ++
Sbjct: 693 DLSKAPEPKKPPPLVKQPTLHGSPSAKAKQPPEADSLSKPAPPKE--------------- 737
Query: 62 VHMVPVVPSKQTSIPQHHSYHQDPVHRQPPASPPRQAGWSSQARPPDPLCLCREPLSRIH 121
P VPS+Q P D +QP P SS + P P S++
Sbjct: 738 ----PSVPSEQDKAPV-----ADDKPKQPKMVKPTTDLVSSSSATTKP----DIPSSKVQ 784
Query: 122 RTSSTLRRRSRTTPGPEEGPSQKVDRAPQPT--LVVMLEDIASPRPPAEGFIDETPNFII 179
+ +TTP P + S K ++ PT V + A PRP ++ I P
Sbjct: 785 S-----QAEEKTTP-PLKTDSAKPSQSFPPTGEKVSPFDSKAIPRPASDSKIISHPGPSS 838
Query: 180 PA---QRAEPMRIVRQPTPPPGDLEPPFQPSALPADPLESPPTAPDPALELPSTPPPSSL 236
+ ++ +P++ +P + P +P A P + PT P P T P
Sbjct: 839 ESKGQKQVDPVQKKEEPKKAQTKMSP--KPDAKPMP--KGSPTPPGPRPTAGQTVP---- 890
Query: 237 LRPRLSPWGLAPLFRSVRSKLESFADIFLTPNKTPQPPPPSPPMKL---------ELKIA 287
P+ SP P +S R L + I P P P + KL +
Sbjct: 891 -TPQQSP---KPQEQSRRFSL-NLGSITDAPKSQPTTPQETVTGKLFGFGASIFSQASNL 945
Query: 288 ISEAEQSGAAEGTASVSPRPPIRQWRTQDHNTPALLPKPSLGRSYSCPDLGPPGPGTCTW 347
IS A Q G + P P++Q + P S G++ P P T
Sbjct: 946 ISTAGQPGP---HSQSGPGAPMKQAPAPSQPPTSQGPPKSTGQAPPAPAKSIPVKKE-TK 1001
Query: 348 PPAPPQPSRPRPRRHTVGGGEMARAPPP 375
PA + + TV E + PPP
Sbjct: 1002 APAAEKLEPKAEQAPTVKRTETEKKPPP 1029
Score = 29.6 bits (65), Expect = 8.0
Identities = 35/132 (26%), Positives = 46/132 (34%), Gaps = 21/132 (15%)
Query: 275 PPSPPMKLELKIAISEAEQSGAAEGTASVSPRPPIRQWRTQDHNTPALLPKPSLGRSYSC 334
PPS + L +K +S + + E P + + PA P+P RS S
Sbjct: 2343 PPSSVIALPMKEQLSTTYFT-SGETFGQEKPASQLPSGSPSVSSLPAK-PRPFF-RSSSL 2399
Query: 335 PDLGPPGPGTCTWPPAPPQPSRPRPRRHTVGGGEMARAPPPPRPCLRKEVFPLGGVGASP 394
P P PP PP P P P PPPP P L P +
Sbjct: 2400 DISAQPPP-----PPPPPPPPPPPP-------------PPPPPPPLPPPTSPKPTILPKK 2441
Query: 395 SLTTSCSSTAST 406
LT + T +T
Sbjct: 2442 KLTVASPVTTAT 2453
>gi|150378539 piccolo isoform 1 [Homo sapiens]
Length = 5142
Score = 65.1 bits (157), Expect = 2e-10
Identities = 98/411 (23%), Positives = 148/411 (36%), Gaps = 59/411 (14%)
Query: 85 PVHRQPPASPPRQAGWSSQARPPDPLCLCREPLSRIHRTSSTLRRRSRTTPGPEEGPSQ- 143
P+ +QPP P+Q G DPL P S + ++ + T P +GP+Q
Sbjct: 210 PLQQQPPKPIPKQQGPGR-----DPLQQDGTPKSISSQQPEKIKSQPPGTGKPIQGPTQT 264
Query: 144 -KVDRAPQPTLVVMLEDIASPRPPAEGFI-DETPNFIIPAQRAEPMRIVRQPTP------ 195
+ D A P + D + P+ + E+ +P+ P ++QPTP
Sbjct: 265 PQTDHAKLP----LQRDASRPQTKQADIVRGESVKPSLPSPSKPP---IQQPTPGKPPAQ 317
Query: 196 -------PPGDLEPPFQPSALPADPLESPPTAPDPALELPSTPPPSSLLRPRLSPWGLAP 248
PG +PP QPS L + P T P +T PP+ L P P A
Sbjct: 318 QPGHEKSQPGPAKPPAQPSGLTKPLAQQPGTVKPPVQPPGTTKPPAQPLGPAKPP---AQ 374
Query: 249 LFRSVRSKLESFADIFLTP----NKTP-QPPPPSPPMKLELKIAISEAEQSGAAEGTASV 303
S + E L KTP Q P P+ P ++ A+Q G +
Sbjct: 375 QTGSEKPSSEQPGPKALAQPPGVGKTPAQQPGPAKPPTQQVGTPKPLAQQPGLQSPAKAP 434
Query: 304 SP-RPPIRQWRTQDHNTPALLPKPSLG-RSYSCPDLGPPGPGTCTWPPAPPQPSRPRPRR 361
P + P++Q P +P G S GP P + PA P P +P P +
Sbjct: 435 GPTKTPVQQ------PGPGKIPAQQAGPGKTSAQQTGPTKPPSQLPGPAKPPPQQPGPAK 488
Query: 362 HTVGGGEMARAPPPPRPCLRKEVFPLGGVGASPSLTTSCS--STASTSFSEPAEPRLGST 419
PPP +P K G P + S ++P + GS
Sbjct: 489 -----------PPPQQPGSAKPPSQQPGSTKPPPQQPGPAKPSPQQPGSTKPPSQQPGSA 537
Query: 420 KGKEPRASKDQVLSEPETKTMGKVSRFRIRRTP-ARPQLNLTP-MGLPRPI 468
K + S + ++ TK + + + + P P P GLP+ I
Sbjct: 538 KPSAQQPSPAKPSAQQSTKPVSQTGSGKPLQPPTVSPSAKQPPSQGLPKTI 588
Score = 62.8 bits (151), Expect = 9e-10
Identities = 100/442 (22%), Positives = 139/442 (31%), Gaps = 86/442 (19%)
Query: 4 PGDSSPPGQPRLCRQPLTRALWGARSPKRPRLQLPGAPSPLEKASRRVLAVVLEDVMAVH 63
PG + PP QP +PL Q PG P
Sbjct: 326 PGPAKPPAQPSGLTKPLA--------------QQPGTVKP-------------------- 351
Query: 64 MVPVVPSKQTSIPQHHSYHQDPVHRQPPASPPRQAGWSSQ--ARPPDPLCLCREPLSRIH 121
PV P T + P PA PP Q S + + P P L + P
Sbjct: 352 --PVQPPGTT---------KPPAQPLGPAKPPAQQTGSEKPSSEQPGPKALAQPP----- 395
Query: 122 RTSSTLRRRSRTTPGPEEGPSQKVDRAPQPTLVVMLEDIASPRPPAEGFIDETPNFIIPA 181
+ + PGP + P+Q+V L+ A P + + + IPA
Sbjct: 396 ----GVGKTPAQQPGPAKPPTQQVGTPKPLAQQPGLQSPAKAPGPTKTPVQQPGPGKIPA 451
Query: 182 QRAEPMRIVRQ---PTPPPGDLEPPFQPSALPADPLESPPTAPDPALELPSTPPPSSLLR 238
Q+A P + Q PT PP L P +P P + PP P A P + P S
Sbjct: 452 QQAGPGKTSAQQTGPTKPPSQLPGPAKPPPQQPGPAKPPPQQPGSA--KPPSQQPGSTKP 509
Query: 239 PRLSPWGLAPLFRSVRSKLESFADIFLTPNKTPQPPPPSPPMKLELKIAISEAEQSGAAE 298
P P P + S QP P P + K
Sbjct: 510 PPQQPGPAKPSPQQPGSTKPPSQQPGSAKPSAQQPSPAKPSAQQSTKPVSQTGSGKPLQP 569
Query: 299 GTASVSPRPPIRQWRTQD-----HNTPALLPKPSLGRSYSCPDLGPPGPGTCTWPPAPPQ 353
T S S + P Q + + T LL P +C + C + P P
Sbjct: 570 PTVSPSAKQPPSQGLPKTICPLCNTTELLLHVPEKANFNTCTECQTTVCSLCGFNPNPHL 629
Query: 354 PSRP-----RPRRHTVGGGEMARAPPPPRPCLRKEVFPLGGVGASPSLTTSCSSTAS--- 405
+ GG++A P P+P L+ +P TTS S +S
Sbjct: 630 TEVKEWLCLNCQMKRALGGDLAPVPSSPQPKLK----------TAPVTTTSAVSKSSPQP 679
Query: 406 --TSFSEPAEPRLGSTKGKEPR 425
TS + A P+ +K EP+
Sbjct: 680 QQTSPKKDAAPKQDLSKAPEPK 701
Score = 49.7 bits (117), Expect = 8e-06
Identities = 52/180 (28%), Positives = 73/180 (40%), Gaps = 25/180 (13%)
Query: 158 EDIASPRPPAEGFIDETPNFIIPAQRAEPMRIVRQPTPPPGDLEPPFQPSALPADPLESP 217
E AS P + P P R+ + I QP PPP PP P P
Sbjct: 2370 EKPASQLPSGSPSVSSLPAKPRPFFRSSSLDISAQPPPPPPPPPPPPPP----------P 2419
Query: 218 PTAPDPALELPSTPPPSSLLRPRL---SPWGLA-PLFRSVRSKLESFADIFLTPNKTP-- 271
P P P L P++P P+ L + +L SP A PLF +V + LE+ A L N P
Sbjct: 2420 PPPPPPPLPPPTSPKPTILPKKKLTVASPVTTATPLFDAV-TTLETTA--VLRSNGLPVT 2476
Query: 272 ----QPPPPSPPMKLELKIAISEAEQSGAAEGTASVSPRPPIRQWRTQDHNTPALLPKPS 327
PPP PP + + + ++ ++P+P I Q T + PKP+
Sbjct: 2477 RICTTAPPPVPPKPSSIPSGLVFTHRPEPSK--PPIAPKPVIPQLPTTTQKPTDIHPKPT 2534
Score = 43.5 bits (101), Expect = 5e-04
Identities = 63/251 (25%), Positives = 87/251 (34%), Gaps = 51/251 (20%)
Query: 223 PALELPSTPPPSSLL--RPRLSPWGLAPLFRSVRSKLESFADIFLTPNKTPQPPPPSPPM 280
PA +LPS P S L +PR P FRS S DI P P PPPP PP
Sbjct: 2372 PASQLPSGSPSVSSLPAKPR-------PFFRS------SSLDISAQPPPPPPPPPPPPP- 2417
Query: 281 KLELKIAISEAEQSGAAEGTASVSPRPPIRQWRTQDHNTPALLPKP------SLGRSYSC 334
SP+P I + +P P +L +
Sbjct: 2418 ---------PPPPPPPPPLPPPTSPKPTILPKKKLTVASPVTTATPLFDAVTTLETTAVL 2468
Query: 335 PDLGPPGPGTCTW--PPAPPQPSRPRPRRHTVGGGEMARAPPPPRPCLRK---------E 383
G P CT PP PP+PS E ++ P P+P + + +
Sbjct: 2469 RSNGLPVTRICTTAPPPVPPKPSSIPSGLVFTHRPEPSKPPIAPKPVIPQLPTTTQKPTD 2528
Query: 384 VFPLG-GVGASPSLTTSCSSTASTSFSEPAEPRLGSTKGKEPRASKD--------QVLSE 434
+ P G+ + S+T + ++A P P + PR SK + SE
Sbjct: 2529 IHPKPTGLSLTSSMTLNLVTSADYKLPSPTSPLSPHSNKSSPRFSKSLTETYVVITLPSE 2588
Query: 435 PETKTMGKVSR 445
P T T S+
Sbjct: 2589 PGTPTDSSASQ 2599
Score = 39.7 bits (91), Expect = 0.008
Identities = 84/409 (20%), Positives = 135/409 (33%), Gaps = 97/409 (23%)
Query: 70 SKQTSIPQHHSYHQDPVHRQPPASPPRQAGWSSQARPPDPLCLCREPLSRIHRTSSTLRR 129
SK + PQ S +D +Q + P P P L ++P +H + S +
Sbjct: 673 SKSSPQPQQTSPKKDAAPKQDLSKAPE---------PKKPPPLVKQPT--LHGSPSAKAK 721
Query: 130 R-----SRTTPGPEEGPS--QKVDRAP-------QPTLVVMLEDIAS----------PRP 165
+ S + P P + PS + D+AP QP +V D+ S P
Sbjct: 722 QPPEADSLSKPAPPKEPSVPSEQDKAPVADDKPKQPKMVKPTTDLVSSSSATTKPDIPSS 781
Query: 166 PAEGFIDETPNFIIPAQRAEPMRIVRQPTPPPGDLEPPFQPSALPADPLESPPTAPDPAL 225
+ +E + A+P Q PP G+ PF A+P +S
Sbjct: 782 KVQSQAEEKTTPPLKTDSAKPS----QSFPPTGEKVSPFDSKAIPRPASDS--------- 828
Query: 226 ELPSTPPPSSLLR--PRLSPWGLAPLFRSVRSKLESFADIFLTPNKTPQPPPPSPPMKLE 283
++ S P PSS + ++ P + ++K+ D P +P PP P P
Sbjct: 829 KIISHPGPSSESKGQKQVDPVQKKEEPKKAQTKMSPKPDAKPMPKGSPTPPGPRP----- 883
Query: 284 LKIAISEAEQSGAAEGTASVSPRPPIRQWRTQDHNTPALLPKPSLGRSYSCPDLGPPGP- 342
+G T SP+P + R +LG P P P
Sbjct: 884 ---------TAGQTVPTPQQSPKPQEQSRRF----------SLNLGSITDAPKSQPTTPQ 924
Query: 343 ----------GTCTWPPAP---PQPSRPRPRRHTVGGGEMARAPPPPRPCLRKEVFPLGG 389
G + A +P P + G M +AP P +P +
Sbjct: 925 ETVTGKLFGFGASIFSQASNLISTAGQPGPHSQSGPGAPMKQAPAPSQPPTSQ------- 977
Query: 390 VGASPSLTTSCSSTASTSFSEPAEPRLGSTKGKEPRASKDQVLSEPETK 438
P T + S E + + + EP+A + + ET+
Sbjct: 978 --GPPKSTGQAPPAPAKSIPVKKETKAPAAEKLEPKAEQAPTVKRTETE 1024
Score = 34.3 bits (77), Expect = 0.33
Identities = 88/388 (22%), Positives = 132/388 (34%), Gaps = 65/388 (16%)
Query: 2 DLPGDSSPPGQPRLCRQPLTRALWGARSPKRPRLQLPGAPSPLEKASRRVLAVVLEDVMA 61
DL P P L +QP A++ + P P+P ++
Sbjct: 693 DLSKAPEPKKPPPLVKQPTLHGSPSAKAKQPPEADSLSKPAPPKE--------------- 737
Query: 62 VHMVPVVPSKQTSIPQHHSYHQDPVHRQPPASPPRQAGWSSQARPPDPLCLCREPLSRIH 121
P VPS+Q P D +QP P SS + P P S++
Sbjct: 738 ----PSVPSEQDKAPV-----ADDKPKQPKMVKPTTDLVSSSSATTKP----DIPSSKVQ 784
Query: 122 RTSSTLRRRSRTTPGPEEGPSQKVDRAPQPT--LVVMLEDIASPRPPAEGFIDETPNFII 179
+ +TTP P + S K ++ PT V + A PRP ++ I P
Sbjct: 785 S-----QAEEKTTP-PLKTDSAKPSQSFPPTGEKVSPFDSKAIPRPASDSKIISHPGPSS 838
Query: 180 PA---QRAEPMRIVRQPTPPPGDLEPPFQPSALPADPLESPPTAPDPALELPSTPPPSSL 236
+ ++ +P++ +P + P +P A P + PT P P T P
Sbjct: 839 ESKGQKQVDPVQKKEEPKKAQTKMSP--KPDAKPMP--KGSPTPPGPRPTAGQTVP---- 890
Query: 237 LRPRLSPWGLAPLFRSVRSKLESFADIFLTPNKTPQPPPPSPPMKL---------ELKIA 287
P+ SP P +S R L + I P P P + KL +
Sbjct: 891 -TPQQSP---KPQEQSRRFSL-NLGSITDAPKSQPTTPQETVTGKLFGFGASIFSQASNL 945
Query: 288 ISEAEQSGAAEGTASVSPRPPIRQWRTQDHNTPALLPKPSLGRSYSCPDLGPPGPGTCTW 347
IS A Q G + P P++Q + P S G++ P P T
Sbjct: 946 ISTAGQPGP---HSQSGPGAPMKQAPAPSQPPTSQGPPKSTGQAPPAPAKSIPVKKE-TK 1001
Query: 348 PPAPPQPSRPRPRRHTVGGGEMARAPPP 375
PA + + TV E + PPP
Sbjct: 1002 APAAEKLEPKAEQAPTVKRTETEKKPPP 1029
Score = 29.6 bits (65), Expect = 8.0
Identities = 35/132 (26%), Positives = 46/132 (34%), Gaps = 21/132 (15%)
Query: 275 PPSPPMKLELKIAISEAEQSGAAEGTASVSPRPPIRQWRTQDHNTPALLPKPSLGRSYSC 334
PPS + L +K +S + + E P + + PA P+P RS S
Sbjct: 2343 PPSSVIALPMKEQLSTTYFT-SGETFGQEKPASQLPSGSPSVSSLPAK-PRPFF-RSSSL 2399
Query: 335 PDLGPPGPGTCTWPPAPPQPSRPRPRRHTVGGGEMARAPPPPRPCLRKEVFPLGGVGASP 394
P P PP PP P P P PPPP P L P +
Sbjct: 2400 DISAQPPP-----PPPPPPPPPPPP-------------PPPPPPPLPPPTSPKPTILPKK 2441
Query: 395 SLTTSCSSTAST 406
LT + T +T
Sbjct: 2442 KLTVASPVTTAT 2453
>gi|189181724 proteoglycan 4 isoform D [Homo sapiens]
Length = 1270
Score = 63.5 bits (153), Expect = 5e-10
Identities = 74/307 (24%), Positives = 94/307 (30%), Gaps = 31/307 (10%)
Query: 134 TPGPEEGPSQKVDRAPQPTLVVMLEDIAS-PRPPAEGFIDETPNFIIPAQRAEPMRIVRQ 192
TP + P+ + P PT + P P TP P EP +
Sbjct: 217 TPTTPKEPASTTPKEPTPTTIKSAPTTPKEPAPTTTKSAPTTPKEPAPTTTKEPAPTTPK 276
Query: 193 PTPPPGDLEP-PFQPSALPADPLESPPTAPD-PALELPSTPPPSSLLRPR-LSPWGLAPL 249
P EP P + P P E PT P PA P P P++ P +P AP
Sbjct: 277 EPAPTTTKEPAPTTTKSAPTTPKEPAPTTPKKPAPTTPKEPAPTTPKEPTPTTPKEPAPT 336
Query: 250 FRSVRSKLESFADIFLTPNKTPQPPPPSPPMKLELKIAISEAEQSGAAEGTASVSPRPPI 309
+ T K P P P P K + A T SP P
Sbjct: 337 TKEPAP----------TTPKEPAPTAPKKPAPTTPKEPAPTTPKEPAPTTTKEPSPTTPK 386
Query: 310 RQWRTQDHNTPALLPKPSLGRSYSCPDLGPPGPGTCTWPPAPPQPSRPRPRRHTVGGGEM 369
T + P +P+ + S P T T PAP P P P
Sbjct: 387 EPAPTTTKSAPTTTKEPAPTTTKSAPTTPKEPSPTTTKEPAPTTPKEPAP---------- 436
Query: 370 ARAPPPPRPCLRKEVFPLGGVGASPSLTTSCSSTASTSFSEPAEPRLGSTKGKEPRASKD 429
P P P KE P +P+ T + T P EP + K P K
Sbjct: 437 -TTPKKPAPTTPKEPAPTTPKEPAPTTTKKPAPTT------PKEPAPTTPKETAPTTPKK 489
Query: 430 QVLSEPE 436
+ PE
Sbjct: 490 LTPTTPE 496
Score = 57.4 bits (137), Expect = 4e-08
Identities = 77/340 (22%), Positives = 111/340 (32%), Gaps = 58/340 (17%)
Query: 88 RQPPASPPRQAGWSSQARPPDPLCLCREPLSRIHRTSSTLRRRSRTTPGPEEGPSQKVDR 147
+ P +P A ++++ P P +EP +T + + TTP + P+ +
Sbjct: 238 KSAPTTPKEPAPTTTKSAPTTP----KEP------APTTTKEPAPTTP---KEPAPTTTK 284
Query: 148 APQPTLVVMLEDIASPRPPAEGFIDETPNFIIPAQRAEPMRIV-RQPTPPPGDLEPPFQP 206
P PT +P+ PA TP P EP ++PTP P
Sbjct: 285 EPAPTTTKSAP--TTPKEPAP----TTPKKPAPTTPKEPAPTTPKEPTPTTPKEPAPTTK 338
Query: 207 SALPADPLESPPTAPD-PALELPSTPPPSSLLRPRLSPWGLAPLFRSVRSKLESFADIFL 265
P P E PTAP PA P P P++ P AP
Sbjct: 339 EPAPTTPKEPAPTAPKKPAPTTPKEPAPTTPKEP-------AP----------------- 374
Query: 266 TPNKTPQPPPPSPPMKLELKIA-ISEAEQSGAAEGTASVSPRPPIRQWRTQDHNTPALLP 324
T K P P P P K A + E + +A +P+ P + T P
Sbjct: 375 TTTKEPSPTTPKEPAPTTTKSAPTTTKEPAPTTTKSAPTTPKEPSPTTTKEPAPTTPKEP 434
Query: 325 KPSLGRSYSCPDLGPPGPGTCTWPPAPPQPSRPRPRRHTVGGGEMARAPPPPRPCLRKEV 384
P+ + P P T P P P+ P+ T P P P KE
Sbjct: 435 APTTPKK--------PAPTT----PKEPAPTTPKEPAPTTTKKPAPTTPKEPAPTTPKET 482
Query: 385 FPLGGVGASPSLTTSCSSTASTSFSEPAEPRLGSTKGKEP 424
P +P+ + T + L T +EP
Sbjct: 483 APTTPKKLTPTTPEKLAPTTPEKPAPTTPEELAPTTPEEP 522
Score = 56.2 bits (134), Expect = 8e-08
Identities = 91/432 (21%), Positives = 142/432 (32%), Gaps = 44/432 (10%)
Query: 68 VPSKQTSIPQHHSYHQDP-VHRQPPASPPRQAGWSSQARPPDPLCLCREPLSRIHRTSST 126
V + TS QH+ P + P +P +S L + +E T++T
Sbjct: 99 VTTPDTSTTQHNKVSTSPKITTAKPINPRPSLPPNSDTSKETSLTVNKETTVETKETTTT 158
Query: 127 LRRRSRTTPGPEEGPSQKVDRAPQPTLVVMLEDIASPRPPAEGFIDETPNFIIPAQRAEP 186
++ S T G E+ S K ++ + T L A
Sbjct: 159 NKQTS--TDGKEKTTSAKETQSIEKTSAKDL--------------------------APT 190
Query: 187 MRIVRQPTPPPGDLEPPFQPSALPADPLESPPTAPDPALELPSTPPPSSLLRPRLSPWGL 246
+++ +PTP E + AL +P T +PA P P P+++ +P
Sbjct: 191 SKVLAKPTPKA---ETTTKGPALTTPKEPTPTTPKEPASTTPKEPTPTTIKSAPTTPKEP 247
Query: 247 APLFRSVRSKLESFADIFLTPNKTPQPPPPSPPMKLELKIAISEAEQSG--AAEGTASVS 304
AP + +S + + T K P P P P K +S + A +
Sbjct: 248 AP--TTTKSAPTTPKEPAPTTTKEPAPTTPKEPAPTTTKEPAPTTTKSAPTTPKEPAPTT 305
Query: 305 PRPPIRQWRTQDHNTPALLPKPSLGRSYSCPDLGPPGPGTCTWPPAPPQPSRPRPRRHTV 364
P+ P + T P P+ + P P P T PAP P +P P
Sbjct: 306 PKKPAPTTPKEPAPTTPKEPTPTTPKE-PAPTTKEPAP-TTPKEPAPTAPKKPAPTTPKE 363
Query: 365 GGGEMARAPPP-----PRPCLRKEVFPLGGVGASPSLTTSCSSTASTSFSEPAEPRLGST 419
+ P P P P KE P A + +T ++ + P EP +T
Sbjct: 364 PAPTTPKEPAPTTTKEPSPTTPKEPAPTTTKSAPTTTKEPAPTTTKSAPTTPKEPSPTTT 423
Query: 420 KGKEPRASKDQVLSEPETKTMGKVSRFRIRRTPARPQLNLTPMGLPRPIRLNKKEFSLEE 479
K P K+ + P+ K + TP P T P + E
Sbjct: 424 KEPAPTTPKEPAPTTPK-KPAPTTPKEPAPTTPKEPAPTTTKKPAPTTPKEPAPTTPKET 482
Query: 480 IYTNKNYQSPTT 491
T +PTT
Sbjct: 483 APTTPKKLTPTT 494
Score = 54.3 bits (129), Expect = 3e-07
Identities = 96/444 (21%), Positives = 135/444 (30%), Gaps = 67/444 (15%)
Query: 31 KRPRLQLPGAPSPL---EKASRRVLAVVLEDVMAVHMVPVVPSKQTSIPQHHSYHQDPVH 87
K P L P P+P E AS + + P P+ T+
Sbjct: 206 KGPALTTPKEPTPTTPKEPASTTPKEPTPTTIKSAPTTPKEPAPTTT------------- 252
Query: 88 RQPPASPPRQAGWSSQARPPDPLCLCREPLSRIHRTSSTLRRRSRTTPGPEEGPSQKVDR 147
+ P +P A + + P P + + T + + TTP + P+ +
Sbjct: 253 KSAPTTPKEPA--PTTTKEPAPTTPKEPAPTTTKEPAPTTTKSAPTTP---KEPAPTTPK 307
Query: 148 APQPTLVVMLEDIASPRPPAEGFIDETPNFIIPAQRAEPMRIVRQPTPP-PGDLEPPFQP 206
P PT +P+ PA TP P EP ++P P P + P
Sbjct: 308 KPAPT---------TPKEPAP----TTPKEPTPTTPKEPAPTTKEPAPTTPKEPAPTAPK 354
Query: 207 SALPADPLESPPTAP---------DPALELPSTPPPSSLL-------RPRLSPWGLAPLF 250
P P E PT P +P+ P P P++ P + AP
Sbjct: 355 KPAPTTPKEPAPTTPKEPAPTTTKEPSPTTPKEPAPTTTKSAPTTTKEPAPTTTKSAPTT 414
Query: 251 RSVRSKLESFADIFLTPNKTPQPPPPSPPMKLELKIAISEAEQSGAAEGTASVSPRPPIR 310
S + TP K P P P P K + A T +P P
Sbjct: 415 PKEPSPTTTKEPAPTTP-KEPAPTTPKKPAPTTPKEPAPTTPKEPAPTTTKKPAPTTPKE 473
Query: 311 QWRTQDHNTPALLPK---PSLGRSYSCPDLGPPGPGT----CTWPPAPPQPSRPRPRRHT 363
T T PK P+ + P P T P P P+ P T
Sbjct: 474 PAPTTPKETAPTTPKKLTPTTPEKLAPTTPEKPAPTTPEELAPTTPEEPTPTTPEEPAPT 533
Query: 364 VGGGEMARAPPPPRPCLRKEVFPLGGVGASP-----SLTTSCSSTASTSFSEPAEPRLGS 418
P P P KE P +P + T+ TA T+ EPA +
Sbjct: 534 TPKAAAPNTPKEPAPTTPKEPAPTTPKEPAPTTPKETAPTTPKGTAPTTLKEPAPT---T 590
Query: 419 TKGKEPRASKDQVLSEPETKTMGK 442
K P+ EP + T K
Sbjct: 591 PKKPAPKELAPTTTKEPTSTTCDK 614
Score = 53.5 bits (127), Expect = 5e-07
Identities = 107/477 (22%), Positives = 161/477 (33%), Gaps = 67/477 (14%)
Query: 29 SPKRPRLQLPGAPSPLEKASRRVLAVVLEDVMAVHMVPVVPSKQTSIPQHHSYHQDPVHR 88
+PK P P P+P K P P + P +
Sbjct: 321 TPKEPTPTTPKEPAPTTKEPAPTTPKEPAPTAPKKPAPTTPKEPA--PTTPKEPAPTTTK 378
Query: 89 QP-PASPPRQAGWSSQARP-----PDPLCLCREPLSRIHRTSSTLRRRSRTTPGPEEGPS 142
+P P +P A ++++ P P P P + + +T + + TTP + P+
Sbjct: 379 EPSPTTPKEPAPTTTKSAPTTTKEPAPTTTKSAPTTPKEPSPTTTKEPAPTTP---KEPA 435
Query: 143 QKVDRAPQPTLVVMLEDIASPRPPAEGFIDETPNFIIPAQRAEPMRIV-RQPTPPPGDLE 201
+ P PT +P+ PA TP P +P ++P P
Sbjct: 436 PTTPKKPAPT---------TPKEPAP----TTPKEPAPTTTKKPAPTTPKEPAPTTPKET 482
Query: 202 PPFQPSAL-PADPLESPPTAPD-PALELPSTPPPSSLLRPR-LSPWGLAPLFRSVRSKLE 258
P P L P P + PT P+ PA P P++ P +P AP +
Sbjct: 483 APTTPKKLTPTTPEKLAPTTPEKPAPTTPEELAPTTPEEPTPTTPEEPAPTTPKAAAPNT 542
Query: 259 SFADIFLTPNK----TPQPPPPSPPMKLELKIAISEAEQSGAAEGTASVSPRPPIRQWRT 314
TP + TP+ P P+ P + + G A T P P +
Sbjct: 543 PKEPAPTTPKEPAPTTPKEPAPTTPKET------APTTPKGTAPTTLK-EPAPTTPKKPA 595
Query: 315 QDHNTPALLPKPSLGRSYSCPDLGPPGP-GTCTWPPAPPQPSRPRPRRHTVGGGEMAR-- 371
P +P+ S +C P P GT P P P+ P+ T G
Sbjct: 596 PKELAPTTTKEPT---STTCDKPAPTTPKGTAPTTPKEPAPTTPKEPAPTTPKGTAPTTL 652
Query: 372 ---APPPPRPCLRKEVFPLGGVGASPSLTTSCSSTASTSFSEPAEPRLGSTKGKEPRASK 428
AP P+ KE+ P G P+ TTS +T P E + K P K
Sbjct: 653 KEPAPTTPKKPAPKELAPTTTKG--PTSTTSDKPAPTT----PKETAPTTPKEPAPTTPK 706
Query: 429 DQVLSEPET--KTMGKVSRFRIRRTP---------ARPQLNLTPMGLPRPIRLNKKE 474
+ PET T +VS + P + P+L+ P P+ + + KE
Sbjct: 707 KPAPTTPETPPPTTSEVSTPTTTKEPTTIHKSPDESTPELSAEP--TPKALENSPKE 761
Score = 32.3 bits (72), Expect = 1.2
Identities = 36/157 (22%), Positives = 53/157 (33%), Gaps = 12/157 (7%)
Query: 355 SRPRPRRHTVGGGEMARAPPPPRPCLRKEVFPLGGVGASPSLTTSCSSTASTSFSEPAEP 414
++P P+ T G P P P KE P P+ TT S+ + P
Sbjct: 195 AKPTPKAETTTKGPALTTPKEPTPTTPKE--PASTTPKEPTPTTIKSAPTTPKEPAPTTT 252
Query: 415 RLGSTKGKEPRASKDQ-----VLSEPETKTMGKVSRFRIRRTPARPQLNLTPMGLPRPIR 469
+ T KEP + + EP T + + + P P+ P +P
Sbjct: 253 KSAPTTPKEPAPTTTKEPAPTTPKEPAPTTTKEPAPTTTKSAPTTPK-EPAPTTPKKPAP 311
Query: 470 LNKKE----FSLEEIYTNKNYQSPTTRRTFETIFEEP 502
KE E T +PTT+ T +EP
Sbjct: 312 TTPKEPAPTTPKEPTPTTPKEPAPTTKEPAPTTPKEP 348
>gi|189181722 proteoglycan 4 isoform C [Homo sapiens]
Length = 1311
Score = 63.5 bits (153), Expect = 5e-10
Identities = 74/307 (24%), Positives = 94/307 (30%), Gaps = 31/307 (10%)
Query: 134 TPGPEEGPSQKVDRAPQPTLVVMLEDIAS-PRPPAEGFIDETPNFIIPAQRAEPMRIVRQ 192
TP + P+ + P PT + P P TP P EP +
Sbjct: 258 TPTTPKEPASTTPKEPTPTTIKSAPTTPKEPAPTTTKSAPTTPKEPAPTTTKEPAPTTPK 317
Query: 193 PTPPPGDLEP-PFQPSALPADPLESPPTAPD-PALELPSTPPPSSLLRPR-LSPWGLAPL 249
P EP P + P P E PT P PA P P P++ P +P AP
Sbjct: 318 EPAPTTTKEPAPTTTKSAPTTPKEPAPTTPKKPAPTTPKEPAPTTPKEPTPTTPKEPAPT 377
Query: 250 FRSVRSKLESFADIFLTPNKTPQPPPPSPPMKLELKIAISEAEQSGAAEGTASVSPRPPI 309
+ T K P P P P K + A T SP P
Sbjct: 378 TKEPAP----------TTPKEPAPTAPKKPAPTTPKEPAPTTPKEPAPTTTKEPSPTTPK 427
Query: 310 RQWRTQDHNTPALLPKPSLGRSYSCPDLGPPGPGTCTWPPAPPQPSRPRPRRHTVGGGEM 369
T + P +P+ + S P T T PAP P P P
Sbjct: 428 EPAPTTTKSAPTTTKEPAPTTTKSAPTTPKEPSPTTTKEPAPTTPKEPAP---------- 477
Query: 370 ARAPPPPRPCLRKEVFPLGGVGASPSLTTSCSSTASTSFSEPAEPRLGSTKGKEPRASKD 429
P P P KE P +P+ T + T P EP + K P K
Sbjct: 478 -TTPKKPAPTTPKEPAPTTPKEPAPTTTKKPAPTT------PKEPAPTTPKETAPTTPKK 530
Query: 430 QVLSEPE 436
+ PE
Sbjct: 531 LTPTTPE 537
Score = 57.4 bits (137), Expect = 4e-08
Identities = 77/340 (22%), Positives = 111/340 (32%), Gaps = 58/340 (17%)
Query: 88 RQPPASPPRQAGWSSQARPPDPLCLCREPLSRIHRTSSTLRRRSRTTPGPEEGPSQKVDR 147
+ P +P A ++++ P P +EP +T + + TTP + P+ +
Sbjct: 279 KSAPTTPKEPAPTTTKSAPTTP----KEP------APTTTKEPAPTTP---KEPAPTTTK 325
Query: 148 APQPTLVVMLEDIASPRPPAEGFIDETPNFIIPAQRAEPMRIV-RQPTPPPGDLEPPFQP 206
P PT +P+ PA TP P EP ++PTP P
Sbjct: 326 EPAPTTTKSAP--TTPKEPAP----TTPKKPAPTTPKEPAPTTPKEPTPTTPKEPAPTTK 379
Query: 207 SALPADPLESPPTAPD-PALELPSTPPPSSLLRPRLSPWGLAPLFRSVRSKLESFADIFL 265
P P E PTAP PA P P P++ P AP
Sbjct: 380 EPAPTTPKEPAPTAPKKPAPTTPKEPAPTTPKEP-------AP----------------- 415
Query: 266 TPNKTPQPPPPSPPMKLELKIA-ISEAEQSGAAEGTASVSPRPPIRQWRTQDHNTPALLP 324
T K P P P P K A + E + +A +P+ P + T P
Sbjct: 416 TTTKEPSPTTPKEPAPTTTKSAPTTTKEPAPTTTKSAPTTPKEPSPTTTKEPAPTTPKEP 475
Query: 325 KPSLGRSYSCPDLGPPGPGTCTWPPAPPQPSRPRPRRHTVGGGEMARAPPPPRPCLRKEV 384
P+ + P P T P P P+ P+ T P P P KE
Sbjct: 476 APTTPKK--------PAPTT----PKEPAPTTPKEPAPTTTKKPAPTTPKEPAPTTPKET 523
Query: 385 FPLGGVGASPSLTTSCSSTASTSFSEPAEPRLGSTKGKEP 424
P +P+ + T + L T +EP
Sbjct: 524 APTTPKKLTPTTPEKLAPTTPEKPAPTTPEELAPTTPEEP 563
Score = 56.2 bits (134), Expect = 8e-08
Identities = 91/432 (21%), Positives = 142/432 (32%), Gaps = 44/432 (10%)
Query: 68 VPSKQTSIPQHHSYHQDP-VHRQPPASPPRQAGWSSQARPPDPLCLCREPLSRIHRTSST 126
V + TS QH+ P + P +P +S L + +E T++T
Sbjct: 140 VTTPDTSTTQHNKVSTSPKITTAKPINPRPSLPPNSDTSKETSLTVNKETTVETKETTTT 199
Query: 127 LRRRSRTTPGPEEGPSQKVDRAPQPTLVVMLEDIASPRPPAEGFIDETPNFIIPAQRAEP 186
++ S T G E+ S K ++ + T L A
Sbjct: 200 NKQTS--TDGKEKTTSAKETQSIEKTSAKDL--------------------------APT 231
Query: 187 MRIVRQPTPPPGDLEPPFQPSALPADPLESPPTAPDPALELPSTPPPSSLLRPRLSPWGL 246
+++ +PTP E + AL +P T +PA P P P+++ +P
Sbjct: 232 SKVLAKPTPKA---ETTTKGPALTTPKEPTPTTPKEPASTTPKEPTPTTIKSAPTTPKEP 288
Query: 247 APLFRSVRSKLESFADIFLTPNKTPQPPPPSPPMKLELKIAISEAEQSG--AAEGTASVS 304
AP + +S + + T K P P P P K +S + A +
Sbjct: 289 AP--TTTKSAPTTPKEPAPTTTKEPAPTTPKEPAPTTTKEPAPTTTKSAPTTPKEPAPTT 346
Query: 305 PRPPIRQWRTQDHNTPALLPKPSLGRSYSCPDLGPPGPGTCTWPPAPPQPSRPRPRRHTV 364
P+ P + T P P+ + P P P T PAP P +P P
Sbjct: 347 PKKPAPTTPKEPAPTTPKEPTPTTPKE-PAPTTKEPAP-TTPKEPAPTAPKKPAPTTPKE 404
Query: 365 GGGEMARAPPP-----PRPCLRKEVFPLGGVGASPSLTTSCSSTASTSFSEPAEPRLGST 419
+ P P P P KE P A + +T ++ + P EP +T
Sbjct: 405 PAPTTPKEPAPTTTKEPSPTTPKEPAPTTTKSAPTTTKEPAPTTTKSAPTTPKEPSPTTT 464
Query: 420 KGKEPRASKDQVLSEPETKTMGKVSRFRIRRTPARPQLNLTPMGLPRPIRLNKKEFSLEE 479
K P K+ + P+ K + TP P T P + E
Sbjct: 465 KEPAPTTPKEPAPTTPK-KPAPTTPKEPAPTTPKEPAPTTTKKPAPTTPKEPAPTTPKET 523
Query: 480 IYTNKNYQSPTT 491
T +PTT
Sbjct: 524 APTTPKKLTPTT 535
Score = 54.3 bits (129), Expect = 3e-07
Identities = 96/444 (21%), Positives = 135/444 (30%), Gaps = 67/444 (15%)
Query: 31 KRPRLQLPGAPSPL---EKASRRVLAVVLEDVMAVHMVPVVPSKQTSIPQHHSYHQDPVH 87
K P L P P+P E AS + + P P+ T+
Sbjct: 247 KGPALTTPKEPTPTTPKEPASTTPKEPTPTTIKSAPTTPKEPAPTTT------------- 293
Query: 88 RQPPASPPRQAGWSSQARPPDPLCLCREPLSRIHRTSSTLRRRSRTTPGPEEGPSQKVDR 147
+ P +P A + + P P + + T + + TTP + P+ +
Sbjct: 294 KSAPTTPKEPA--PTTTKEPAPTTPKEPAPTTTKEPAPTTTKSAPTTP---KEPAPTTPK 348
Query: 148 APQPTLVVMLEDIASPRPPAEGFIDETPNFIIPAQRAEPMRIVRQPTPP-PGDLEPPFQP 206
P PT +P+ PA TP P EP ++P P P + P
Sbjct: 349 KPAPT---------TPKEPAP----TTPKEPTPTTPKEPAPTTKEPAPTTPKEPAPTAPK 395
Query: 207 SALPADPLESPPTAP---------DPALELPSTPPPSSLL-------RPRLSPWGLAPLF 250
P P E PT P +P+ P P P++ P + AP
Sbjct: 396 KPAPTTPKEPAPTTPKEPAPTTTKEPSPTTPKEPAPTTTKSAPTTTKEPAPTTTKSAPTT 455
Query: 251 RSVRSKLESFADIFLTPNKTPQPPPPSPPMKLELKIAISEAEQSGAAEGTASVSPRPPIR 310
S + TP K P P P P K + A T +P P
Sbjct: 456 PKEPSPTTTKEPAPTTP-KEPAPTTPKKPAPTTPKEPAPTTPKEPAPTTTKKPAPTTPKE 514
Query: 311 QWRTQDHNTPALLPK---PSLGRSYSCPDLGPPGPGT----CTWPPAPPQPSRPRPRRHT 363
T T PK P+ + P P T P P P+ P T
Sbjct: 515 PAPTTPKETAPTTPKKLTPTTPEKLAPTTPEKPAPTTPEELAPTTPEEPTPTTPEEPAPT 574
Query: 364 VGGGEMARAPPPPRPCLRKEVFPLGGVGASP-----SLTTSCSSTASTSFSEPAEPRLGS 418
P P P KE P +P + T+ TA T+ EPA +
Sbjct: 575 TPKAAAPNTPKEPAPTTPKEPAPTTPKEPAPTTPKETAPTTPKGTAPTTLKEPAPT---T 631
Query: 419 TKGKEPRASKDQVLSEPETKTMGK 442
K P+ EP + T K
Sbjct: 632 PKKPAPKELAPTTTKEPTSTTCDK 655
Score = 53.5 bits (127), Expect = 5e-07
Identities = 107/477 (22%), Positives = 161/477 (33%), Gaps = 67/477 (14%)
Query: 29 SPKRPRLQLPGAPSPLEKASRRVLAVVLEDVMAVHMVPVVPSKQTSIPQHHSYHQDPVHR 88
+PK P P P+P K P P + P +
Sbjct: 362 TPKEPTPTTPKEPAPTTKEPAPTTPKEPAPTAPKKPAPTTPKEPA--PTTPKEPAPTTTK 419
Query: 89 QP-PASPPRQAGWSSQARP-----PDPLCLCREPLSRIHRTSSTLRRRSRTTPGPEEGPS 142
+P P +P A ++++ P P P P + + +T + + TTP + P+
Sbjct: 420 EPSPTTPKEPAPTTTKSAPTTTKEPAPTTTKSAPTTPKEPSPTTTKEPAPTTP---KEPA 476
Query: 143 QKVDRAPQPTLVVMLEDIASPRPPAEGFIDETPNFIIPAQRAEPMRIV-RQPTPPPGDLE 201
+ P PT +P+ PA TP P +P ++P P
Sbjct: 477 PTTPKKPAPT---------TPKEPAP----TTPKEPAPTTTKKPAPTTPKEPAPTTPKET 523
Query: 202 PPFQPSAL-PADPLESPPTAPD-PALELPSTPPPSSLLRPR-LSPWGLAPLFRSVRSKLE 258
P P L P P + PT P+ PA P P++ P +P AP +
Sbjct: 524 APTTPKKLTPTTPEKLAPTTPEKPAPTTPEELAPTTPEEPTPTTPEEPAPTTPKAAAPNT 583
Query: 259 SFADIFLTPNK----TPQPPPPSPPMKLELKIAISEAEQSGAAEGTASVSPRPPIRQWRT 314
TP + TP+ P P+ P + + G A T P P +
Sbjct: 584 PKEPAPTTPKEPAPTTPKEPAPTTPKET------APTTPKGTAPTTLK-EPAPTTPKKPA 636
Query: 315 QDHNTPALLPKPSLGRSYSCPDLGPPGP-GTCTWPPAPPQPSRPRPRRHTVGGGEMAR-- 371
P +P+ S +C P P GT P P P+ P+ T G
Sbjct: 637 PKELAPTTTKEPT---STTCDKPAPTTPKGTAPTTPKEPAPTTPKEPAPTTPKGTAPTTL 693
Query: 372 ---APPPPRPCLRKEVFPLGGVGASPSLTTSCSSTASTSFSEPAEPRLGSTKGKEPRASK 428
AP P+ KE+ P G P+ TTS +T P E + K P K
Sbjct: 694 KEPAPTTPKKPAPKELAPTTTKG--PTSTTSDKPAPTT----PKETAPTTPKEPAPTTPK 747
Query: 429 DQVLSEPET--KTMGKVSRFRIRRTP---------ARPQLNLTPMGLPRPIRLNKKE 474
+ PET T +VS + P + P+L+ P P+ + + KE
Sbjct: 748 KPAPTTPETPPPTTSEVSTPTTTKEPTTIHKSPDESTPELSAEP--TPKALENSPKE 802
Score = 32.3 bits (72), Expect = 1.2
Identities = 36/157 (22%), Positives = 53/157 (33%), Gaps = 12/157 (7%)
Query: 355 SRPRPRRHTVGGGEMARAPPPPRPCLRKEVFPLGGVGASPSLTTSCSSTASTSFSEPAEP 414
++P P+ T G P P P KE P P+ TT S+ + P
Sbjct: 236 AKPTPKAETTTKGPALTTPKEPTPTTPKE--PASTTPKEPTPTTIKSAPTTPKEPAPTTT 293
Query: 415 RLGSTKGKEPRASKDQ-----VLSEPETKTMGKVSRFRIRRTPARPQLNLTPMGLPRPIR 469
+ T KEP + + EP T + + + P P+ P +P
Sbjct: 294 KSAPTTPKEPAPTTTKEPAPTTPKEPAPTTTKEPAPTTTKSAPTTPK-EPAPTTPKKPAP 352
Query: 470 LNKKE----FSLEEIYTNKNYQSPTTRRTFETIFEEP 502
KE E T +PTT+ T +EP
Sbjct: 353 TTPKEPAPTTPKEPTPTTPKEPAPTTKEPAPTTPKEP 389
>gi|189181720 proteoglycan 4 isoform B [Homo sapiens]
Length = 1363
Score = 63.5 bits (153), Expect = 5e-10
Identities = 74/307 (24%), Positives = 94/307 (30%), Gaps = 31/307 (10%)
Query: 134 TPGPEEGPSQKVDRAPQPTLVVMLEDIAS-PRPPAEGFIDETPNFIIPAQRAEPMRIVRQ 192
TP + P+ + P PT + P P TP P EP +
Sbjct: 310 TPTTPKEPASTTPKEPTPTTIKSAPTTPKEPAPTTTKSAPTTPKEPAPTTTKEPAPTTPK 369
Query: 193 PTPPPGDLEP-PFQPSALPADPLESPPTAPD-PALELPSTPPPSSLLRPR-LSPWGLAPL 249
P EP P + P P E PT P PA P P P++ P +P AP
Sbjct: 370 EPAPTTTKEPAPTTTKSAPTTPKEPAPTTPKKPAPTTPKEPAPTTPKEPTPTTPKEPAPT 429
Query: 250 FRSVRSKLESFADIFLTPNKTPQPPPPSPPMKLELKIAISEAEQSGAAEGTASVSPRPPI 309
+ T K P P P P K + A T SP P
Sbjct: 430 TKEPAP----------TTPKEPAPTAPKKPAPTTPKEPAPTTPKEPAPTTTKEPSPTTPK 479
Query: 310 RQWRTQDHNTPALLPKPSLGRSYSCPDLGPPGPGTCTWPPAPPQPSRPRPRRHTVGGGEM 369
T + P +P+ + S P T T PAP P P P
Sbjct: 480 EPAPTTTKSAPTTTKEPAPTTTKSAPTTPKEPSPTTTKEPAPTTPKEPAP---------- 529
Query: 370 ARAPPPPRPCLRKEVFPLGGVGASPSLTTSCSSTASTSFSEPAEPRLGSTKGKEPRASKD 429
P P P KE P +P+ T + T P EP + K P K
Sbjct: 530 -TTPKKPAPTTPKEPAPTTPKEPAPTTTKKPAPTT------PKEPAPTTPKETAPTTPKK 582
Query: 430 QVLSEPE 436
+ PE
Sbjct: 583 LTPTTPE 589
Score = 57.4 bits (137), Expect = 4e-08
Identities = 77/340 (22%), Positives = 111/340 (32%), Gaps = 58/340 (17%)
Query: 88 RQPPASPPRQAGWSSQARPPDPLCLCREPLSRIHRTSSTLRRRSRTTPGPEEGPSQKVDR 147
+ P +P A ++++ P P +EP +T + + TTP + P+ +
Sbjct: 331 KSAPTTPKEPAPTTTKSAPTTP----KEP------APTTTKEPAPTTP---KEPAPTTTK 377
Query: 148 APQPTLVVMLEDIASPRPPAEGFIDETPNFIIPAQRAEPMRIV-RQPTPPPGDLEPPFQP 206
P PT +P+ PA TP P EP ++PTP P
Sbjct: 378 EPAPTTTKSAP--TTPKEPAP----TTPKKPAPTTPKEPAPTTPKEPTPTTPKEPAPTTK 431
Query: 207 SALPADPLESPPTAPD-PALELPSTPPPSSLLRPRLSPWGLAPLFRSVRSKLESFADIFL 265
P P E PTAP PA P P P++ P AP
Sbjct: 432 EPAPTTPKEPAPTAPKKPAPTTPKEPAPTTPKEP-------AP----------------- 467
Query: 266 TPNKTPQPPPPSPPMKLELKIA-ISEAEQSGAAEGTASVSPRPPIRQWRTQDHNTPALLP 324
T K P P P P K A + E + +A +P+ P + T P
Sbjct: 468 TTTKEPSPTTPKEPAPTTTKSAPTTTKEPAPTTTKSAPTTPKEPSPTTTKEPAPTTPKEP 527
Query: 325 KPSLGRSYSCPDLGPPGPGTCTWPPAPPQPSRPRPRRHTVGGGEMARAPPPPRPCLRKEV 384
P+ + P P T P P P+ P+ T P P P KE
Sbjct: 528 APTTPKK--------PAPTT----PKEPAPTTPKEPAPTTTKKPAPTTPKEPAPTTPKET 575
Query: 385 FPLGGVGASPSLTTSCSSTASTSFSEPAEPRLGSTKGKEP 424
P +P+ + T + L T +EP
Sbjct: 576 APTTPKKLTPTTPEKLAPTTPEKPAPTTPEELAPTTPEEP 615
Score = 56.2 bits (134), Expect = 8e-08
Identities = 91/432 (21%), Positives = 142/432 (32%), Gaps = 44/432 (10%)
Query: 68 VPSKQTSIPQHHSYHQDP-VHRQPPASPPRQAGWSSQARPPDPLCLCREPLSRIHRTSST 126
V + TS QH+ P + P +P +S L + +E T++T
Sbjct: 192 VTTPDTSTTQHNKVSTSPKITTAKPINPRPSLPPNSDTSKETSLTVNKETTVETKETTTT 251
Query: 127 LRRRSRTTPGPEEGPSQKVDRAPQPTLVVMLEDIASPRPPAEGFIDETPNFIIPAQRAEP 186
++ S T G E+ S K ++ + T L A
Sbjct: 252 NKQTS--TDGKEKTTSAKETQSIEKTSAKDL--------------------------APT 283
Query: 187 MRIVRQPTPPPGDLEPPFQPSALPADPLESPPTAPDPALELPSTPPPSSLLRPRLSPWGL 246
+++ +PTP E + AL +P T +PA P P P+++ +P
Sbjct: 284 SKVLAKPTPKA---ETTTKGPALTTPKEPTPTTPKEPASTTPKEPTPTTIKSAPTTPKEP 340
Query: 247 APLFRSVRSKLESFADIFLTPNKTPQPPPPSPPMKLELKIAISEAEQSG--AAEGTASVS 304
AP + +S + + T K P P P P K +S + A +
Sbjct: 341 AP--TTTKSAPTTPKEPAPTTTKEPAPTTPKEPAPTTTKEPAPTTTKSAPTTPKEPAPTT 398
Query: 305 PRPPIRQWRTQDHNTPALLPKPSLGRSYSCPDLGPPGPGTCTWPPAPPQPSRPRPRRHTV 364
P+ P + T P P+ + P P P T PAP P +P P
Sbjct: 399 PKKPAPTTPKEPAPTTPKEPTPTTPKE-PAPTTKEPAP-TTPKEPAPTAPKKPAPTTPKE 456
Query: 365 GGGEMARAPPP-----PRPCLRKEVFPLGGVGASPSLTTSCSSTASTSFSEPAEPRLGST 419
+ P P P P KE P A + +T ++ + P EP +T
Sbjct: 457 PAPTTPKEPAPTTTKEPSPTTPKEPAPTTTKSAPTTTKEPAPTTTKSAPTTPKEPSPTTT 516
Query: 420 KGKEPRASKDQVLSEPETKTMGKVSRFRIRRTPARPQLNLTPMGLPRPIRLNKKEFSLEE 479
K P K+ + P+ K + TP P T P + E
Sbjct: 517 KEPAPTTPKEPAPTTPK-KPAPTTPKEPAPTTPKEPAPTTTKKPAPTTPKEPAPTTPKET 575
Query: 480 IYTNKNYQSPTT 491
T +PTT
Sbjct: 576 APTTPKKLTPTT 587
Score = 54.3 bits (129), Expect = 3e-07
Identities = 96/444 (21%), Positives = 135/444 (30%), Gaps = 67/444 (15%)
Query: 31 KRPRLQLPGAPSPL---EKASRRVLAVVLEDVMAVHMVPVVPSKQTSIPQHHSYHQDPVH 87
K P L P P+P E AS + + P P+ T+
Sbjct: 299 KGPALTTPKEPTPTTPKEPASTTPKEPTPTTIKSAPTTPKEPAPTTT------------- 345
Query: 88 RQPPASPPRQAGWSSQARPPDPLCLCREPLSRIHRTSSTLRRRSRTTPGPEEGPSQKVDR 147
+ P +P A + + P P + + T + + TTP + P+ +
Sbjct: 346 KSAPTTPKEPA--PTTTKEPAPTTPKEPAPTTTKEPAPTTTKSAPTTP---KEPAPTTPK 400
Query: 148 APQPTLVVMLEDIASPRPPAEGFIDETPNFIIPAQRAEPMRIVRQPTPP-PGDLEPPFQP 206
P PT +P+ PA TP P EP ++P P P + P
Sbjct: 401 KPAPT---------TPKEPAP----TTPKEPTPTTPKEPAPTTKEPAPTTPKEPAPTAPK 447
Query: 207 SALPADPLESPPTAP---------DPALELPSTPPPSSLL-------RPRLSPWGLAPLF 250
P P E PT P +P+ P P P++ P + AP
Sbjct: 448 KPAPTTPKEPAPTTPKEPAPTTTKEPSPTTPKEPAPTTTKSAPTTTKEPAPTTTKSAPTT 507
Query: 251 RSVRSKLESFADIFLTPNKTPQPPPPSPPMKLELKIAISEAEQSGAAEGTASVSPRPPIR 310
S + TP K P P P P K + A T +P P
Sbjct: 508 PKEPSPTTTKEPAPTTP-KEPAPTTPKKPAPTTPKEPAPTTPKEPAPTTTKKPAPTTPKE 566
Query: 311 QWRTQDHNTPALLPK---PSLGRSYSCPDLGPPGPGT----CTWPPAPPQPSRPRPRRHT 363
T T PK P+ + P P T P P P+ P T
Sbjct: 567 PAPTTPKETAPTTPKKLTPTTPEKLAPTTPEKPAPTTPEELAPTTPEEPTPTTPEEPAPT 626
Query: 364 VGGGEMARAPPPPRPCLRKEVFPLGGVGASP-----SLTTSCSSTASTSFSEPAEPRLGS 418
P P P KE P +P + T+ TA T+ EPA +
Sbjct: 627 TPKAAAPNTPKEPAPTTPKEPAPTTPKEPAPTTPKETAPTTPKGTAPTTLKEPAPT---T 683
Query: 419 TKGKEPRASKDQVLSEPETKTMGK 442
K P+ EP + T K
Sbjct: 684 PKKPAPKELAPTTTKEPTSTTCDK 707
Score = 53.5 bits (127), Expect = 5e-07
Identities = 107/477 (22%), Positives = 161/477 (33%), Gaps = 67/477 (14%)
Query: 29 SPKRPRLQLPGAPSPLEKASRRVLAVVLEDVMAVHMVPVVPSKQTSIPQHHSYHQDPVHR 88
+PK P P P+P K P P + P +
Sbjct: 414 TPKEPTPTTPKEPAPTTKEPAPTTPKEPAPTAPKKPAPTTPKEPA--PTTPKEPAPTTTK 471
Query: 89 QP-PASPPRQAGWSSQARP-----PDPLCLCREPLSRIHRTSSTLRRRSRTTPGPEEGPS 142
+P P +P A ++++ P P P P + + +T + + TTP + P+
Sbjct: 472 EPSPTTPKEPAPTTTKSAPTTTKEPAPTTTKSAPTTPKEPSPTTTKEPAPTTP---KEPA 528
Query: 143 QKVDRAPQPTLVVMLEDIASPRPPAEGFIDETPNFIIPAQRAEPMRIV-RQPTPPPGDLE 201
+ P PT +P+ PA TP P +P ++P P
Sbjct: 529 PTTPKKPAPT---------TPKEPAP----TTPKEPAPTTTKKPAPTTPKEPAPTTPKET 575
Query: 202 PPFQPSAL-PADPLESPPTAPD-PALELPSTPPPSSLLRPR-LSPWGLAPLFRSVRSKLE 258
P P L P P + PT P+ PA P P++ P +P AP +
Sbjct: 576 APTTPKKLTPTTPEKLAPTTPEKPAPTTPEELAPTTPEEPTPTTPEEPAPTTPKAAAPNT 635
Query: 259 SFADIFLTPNK----TPQPPPPSPPMKLELKIAISEAEQSGAAEGTASVSPRPPIRQWRT 314
TP + TP+ P P+ P + + G A T P P +
Sbjct: 636 PKEPAPTTPKEPAPTTPKEPAPTTPKET------APTTPKGTAPTTLK-EPAPTTPKKPA 688
Query: 315 QDHNTPALLPKPSLGRSYSCPDLGPPGP-GTCTWPPAPPQPSRPRPRRHTVGGGEMAR-- 371
P +P+ S +C P P GT P P P+ P+ T G
Sbjct: 689 PKELAPTTTKEPT---STTCDKPAPTTPKGTAPTTPKEPAPTTPKEPAPTTPKGTAPTTL 745
Query: 372 ---APPPPRPCLRKEVFPLGGVGASPSLTTSCSSTASTSFSEPAEPRLGSTKGKEPRASK 428
AP P+ KE+ P G P+ TTS +T P E + K P K
Sbjct: 746 KEPAPTTPKKPAPKELAPTTTKG--PTSTTSDKPAPTT----PKETAPTTPKEPAPTTPK 799
Query: 429 DQVLSEPET--KTMGKVSRFRIRRTP---------ARPQLNLTPMGLPRPIRLNKKE 474
+ PET T +VS + P + P+L+ P P+ + + KE
Sbjct: 800 KPAPTTPETPPPTTSEVSTPTTTKEPTTIHKSPDESTPELSAEP--TPKALENSPKE 854
Score = 32.3 bits (72), Expect = 1.2
Identities = 36/157 (22%), Positives = 53/157 (33%), Gaps = 12/157 (7%)
Query: 355 SRPRPRRHTVGGGEMARAPPPPRPCLRKEVFPLGGVGASPSLTTSCSSTASTSFSEPAEP 414
++P P+ T G P P P KE P P+ TT S+ + P
Sbjct: 288 AKPTPKAETTTKGPALTTPKEPTPTTPKE--PASTTPKEPTPTTIKSAPTTPKEPAPTTT 345
Query: 415 RLGSTKGKEPRASKDQ-----VLSEPETKTMGKVSRFRIRRTPARPQLNLTPMGLPRPIR 469
+ T KEP + + EP T + + + P P+ P +P
Sbjct: 346 KSAPTTPKEPAPTTTKEPAPTTPKEPAPTTTKEPAPTTTKSAPTTPK-EPAPTTPKKPAP 404
Query: 470 LNKKE----FSLEEIYTNKNYQSPTTRRTFETIFEEP 502
KE E T +PTT+ T +EP
Sbjct: 405 TTPKEPAPTTPKEPTPTTPKEPAPTTKEPAPTTPKEP 441
>gi|67190163 proteoglycan 4 isoform A [Homo sapiens]
Length = 1404
Score = 63.5 bits (153), Expect = 5e-10
Identities = 74/307 (24%), Positives = 94/307 (30%), Gaps = 31/307 (10%)
Query: 134 TPGPEEGPSQKVDRAPQPTLVVMLEDIAS-PRPPAEGFIDETPNFIIPAQRAEPMRIVRQ 192
TP + P+ + P PT + P P TP P EP +
Sbjct: 351 TPTTPKEPASTTPKEPTPTTIKSAPTTPKEPAPTTTKSAPTTPKEPAPTTTKEPAPTTPK 410
Query: 193 PTPPPGDLEP-PFQPSALPADPLESPPTAPD-PALELPSTPPPSSLLRPR-LSPWGLAPL 249
P EP P + P P E PT P PA P P P++ P +P AP
Sbjct: 411 EPAPTTTKEPAPTTTKSAPTTPKEPAPTTPKKPAPTTPKEPAPTTPKEPTPTTPKEPAPT 470
Query: 250 FRSVRSKLESFADIFLTPNKTPQPPPPSPPMKLELKIAISEAEQSGAAEGTASVSPRPPI 309
+ T K P P P P K + A T SP P
Sbjct: 471 TKEPAP----------TTPKEPAPTAPKKPAPTTPKEPAPTTPKEPAPTTTKEPSPTTPK 520
Query: 310 RQWRTQDHNTPALLPKPSLGRSYSCPDLGPPGPGTCTWPPAPPQPSRPRPRRHTVGGGEM 369
T + P +P+ + S P T T PAP P P P
Sbjct: 521 EPAPTTTKSAPTTTKEPAPTTTKSAPTTPKEPSPTTTKEPAPTTPKEPAP---------- 570
Query: 370 ARAPPPPRPCLRKEVFPLGGVGASPSLTTSCSSTASTSFSEPAEPRLGSTKGKEPRASKD 429
P P P KE P +P+ T + T P EP + K P K
Sbjct: 571 -TTPKKPAPTTPKEPAPTTPKEPAPTTTKKPAPTT------PKEPAPTTPKETAPTTPKK 623
Query: 430 QVLSEPE 436
+ PE
Sbjct: 624 LTPTTPE 630
Score = 57.4 bits (137), Expect = 4e-08
Identities = 77/340 (22%), Positives = 111/340 (32%), Gaps = 58/340 (17%)
Query: 88 RQPPASPPRQAGWSSQARPPDPLCLCREPLSRIHRTSSTLRRRSRTTPGPEEGPSQKVDR 147
+ P +P A ++++ P P +EP +T + + TTP + P+ +
Sbjct: 372 KSAPTTPKEPAPTTTKSAPTTP----KEP------APTTTKEPAPTTP---KEPAPTTTK 418
Query: 148 APQPTLVVMLEDIASPRPPAEGFIDETPNFIIPAQRAEPMRIV-RQPTPPPGDLEPPFQP 206
P PT +P+ PA TP P EP ++PTP P
Sbjct: 419 EPAPTTTKSAP--TTPKEPAP----TTPKKPAPTTPKEPAPTTPKEPTPTTPKEPAPTTK 472
Query: 207 SALPADPLESPPTAPD-PALELPSTPPPSSLLRPRLSPWGLAPLFRSVRSKLESFADIFL 265
P P E PTAP PA P P P++ P AP
Sbjct: 473 EPAPTTPKEPAPTAPKKPAPTTPKEPAPTTPKEP-------AP----------------- 508
Query: 266 TPNKTPQPPPPSPPMKLELKIA-ISEAEQSGAAEGTASVSPRPPIRQWRTQDHNTPALLP 324
T K P P P P K A + E + +A +P+ P + T P
Sbjct: 509 TTTKEPSPTTPKEPAPTTTKSAPTTTKEPAPTTTKSAPTTPKEPSPTTTKEPAPTTPKEP 568
Query: 325 KPSLGRSYSCPDLGPPGPGTCTWPPAPPQPSRPRPRRHTVGGGEMARAPPPPRPCLRKEV 384
P+ + P P T P P P+ P+ T P P P KE
Sbjct: 569 APTTPKK--------PAPTT----PKEPAPTTPKEPAPTTTKKPAPTTPKEPAPTTPKET 616
Query: 385 FPLGGVGASPSLTTSCSSTASTSFSEPAEPRLGSTKGKEP 424
P +P+ + T + L T +EP
Sbjct: 617 APTTPKKLTPTTPEKLAPTTPEKPAPTTPEELAPTTPEEP 656
Score = 56.2 bits (134), Expect = 8e-08
Identities = 91/432 (21%), Positives = 142/432 (32%), Gaps = 44/432 (10%)
Query: 68 VPSKQTSIPQHHSYHQDP-VHRQPPASPPRQAGWSSQARPPDPLCLCREPLSRIHRTSST 126
V + TS QH+ P + P +P +S L + +E T++T
Sbjct: 233 VTTPDTSTTQHNKVSTSPKITTAKPINPRPSLPPNSDTSKETSLTVNKETTVETKETTTT 292
Query: 127 LRRRSRTTPGPEEGPSQKVDRAPQPTLVVMLEDIASPRPPAEGFIDETPNFIIPAQRAEP 186
++ S T G E+ S K ++ + T L A
Sbjct: 293 NKQTS--TDGKEKTTSAKETQSIEKTSAKDL--------------------------APT 324
Query: 187 MRIVRQPTPPPGDLEPPFQPSALPADPLESPPTAPDPALELPSTPPPSSLLRPRLSPWGL 246
+++ +PTP E + AL +P T +PA P P P+++ +P
Sbjct: 325 SKVLAKPTPKA---ETTTKGPALTTPKEPTPTTPKEPASTTPKEPTPTTIKSAPTTPKEP 381
Query: 247 APLFRSVRSKLESFADIFLTPNKTPQPPPPSPPMKLELKIAISEAEQSG--AAEGTASVS 304
AP + +S + + T K P P P P K +S + A +
Sbjct: 382 AP--TTTKSAPTTPKEPAPTTTKEPAPTTPKEPAPTTTKEPAPTTTKSAPTTPKEPAPTT 439
Query: 305 PRPPIRQWRTQDHNTPALLPKPSLGRSYSCPDLGPPGPGTCTWPPAPPQPSRPRPRRHTV 364
P+ P + T P P+ + P P P T PAP P +P P
Sbjct: 440 PKKPAPTTPKEPAPTTPKEPTPTTPKE-PAPTTKEPAP-TTPKEPAPTAPKKPAPTTPKE 497
Query: 365 GGGEMARAPPP-----PRPCLRKEVFPLGGVGASPSLTTSCSSTASTSFSEPAEPRLGST 419
+ P P P P KE P A + +T ++ + P EP +T
Sbjct: 498 PAPTTPKEPAPTTTKEPSPTTPKEPAPTTTKSAPTTTKEPAPTTTKSAPTTPKEPSPTTT 557
Query: 420 KGKEPRASKDQVLSEPETKTMGKVSRFRIRRTPARPQLNLTPMGLPRPIRLNKKEFSLEE 479
K P K+ + P+ K + TP P T P + E
Sbjct: 558 KEPAPTTPKEPAPTTPK-KPAPTTPKEPAPTTPKEPAPTTTKKPAPTTPKEPAPTTPKET 616
Query: 480 IYTNKNYQSPTT 491
T +PTT
Sbjct: 617 APTTPKKLTPTT 628
Score = 54.3 bits (129), Expect = 3e-07
Identities = 96/444 (21%), Positives = 135/444 (30%), Gaps = 67/444 (15%)
Query: 31 KRPRLQLPGAPSPL---EKASRRVLAVVLEDVMAVHMVPVVPSKQTSIPQHHSYHQDPVH 87
K P L P P+P E AS + + P P+ T+
Sbjct: 340 KGPALTTPKEPTPTTPKEPASTTPKEPTPTTIKSAPTTPKEPAPTTT------------- 386
Query: 88 RQPPASPPRQAGWSSQARPPDPLCLCREPLSRIHRTSSTLRRRSRTTPGPEEGPSQKVDR 147
+ P +P A + + P P + + T + + TTP + P+ +
Sbjct: 387 KSAPTTPKEPA--PTTTKEPAPTTPKEPAPTTTKEPAPTTTKSAPTTP---KEPAPTTPK 441
Query: 148 APQPTLVVMLEDIASPRPPAEGFIDETPNFIIPAQRAEPMRIVRQPTPP-PGDLEPPFQP 206
P PT +P+ PA TP P EP ++P P P + P
Sbjct: 442 KPAPT---------TPKEPAP----TTPKEPTPTTPKEPAPTTKEPAPTTPKEPAPTAPK 488
Query: 207 SALPADPLESPPTAP---------DPALELPSTPPPSSLL-------RPRLSPWGLAPLF 250
P P E PT P +P+ P P P++ P + AP
Sbjct: 489 KPAPTTPKEPAPTTPKEPAPTTTKEPSPTTPKEPAPTTTKSAPTTTKEPAPTTTKSAPTT 548
Query: 251 RSVRSKLESFADIFLTPNKTPQPPPPSPPMKLELKIAISEAEQSGAAEGTASVSPRPPIR 310
S + TP K P P P P K + A T +P P
Sbjct: 549 PKEPSPTTTKEPAPTTP-KEPAPTTPKKPAPTTPKEPAPTTPKEPAPTTTKKPAPTTPKE 607
Query: 311 QWRTQDHNTPALLPK---PSLGRSYSCPDLGPPGPGT----CTWPPAPPQPSRPRPRRHT 363
T T PK P+ + P P T P P P+ P T
Sbjct: 608 PAPTTPKETAPTTPKKLTPTTPEKLAPTTPEKPAPTTPEELAPTTPEEPTPTTPEEPAPT 667
Query: 364 VGGGEMARAPPPPRPCLRKEVFPLGGVGASP-----SLTTSCSSTASTSFSEPAEPRLGS 418
P P P KE P +P + T+ TA T+ EPA +
Sbjct: 668 TPKAAAPNTPKEPAPTTPKEPAPTTPKEPAPTTPKETAPTTPKGTAPTTLKEPAPT---T 724
Query: 419 TKGKEPRASKDQVLSEPETKTMGK 442
K P+ EP + T K
Sbjct: 725 PKKPAPKELAPTTTKEPTSTTCDK 748
Score = 53.5 bits (127), Expect = 5e-07
Identities = 107/477 (22%), Positives = 161/477 (33%), Gaps = 67/477 (14%)
Query: 29 SPKRPRLQLPGAPSPLEKASRRVLAVVLEDVMAVHMVPVVPSKQTSIPQHHSYHQDPVHR 88
+PK P P P+P K P P + P +
Sbjct: 455 TPKEPTPTTPKEPAPTTKEPAPTTPKEPAPTAPKKPAPTTPKEPA--PTTPKEPAPTTTK 512
Query: 89 QP-PASPPRQAGWSSQARP-----PDPLCLCREPLSRIHRTSSTLRRRSRTTPGPEEGPS 142
+P P +P A ++++ P P P P + + +T + + TTP + P+
Sbjct: 513 EPSPTTPKEPAPTTTKSAPTTTKEPAPTTTKSAPTTPKEPSPTTTKEPAPTTP---KEPA 569
Query: 143 QKVDRAPQPTLVVMLEDIASPRPPAEGFIDETPNFIIPAQRAEPMRIV-RQPTPPPGDLE 201
+ P PT +P+ PA TP P +P ++P P
Sbjct: 570 PTTPKKPAPT---------TPKEPAP----TTPKEPAPTTTKKPAPTTPKEPAPTTPKET 616
Query: 202 PPFQPSAL-PADPLESPPTAPD-PALELPSTPPPSSLLRPR-LSPWGLAPLFRSVRSKLE 258
P P L P P + PT P+ PA P P++ P +P AP +
Sbjct: 617 APTTPKKLTPTTPEKLAPTTPEKPAPTTPEELAPTTPEEPTPTTPEEPAPTTPKAAAPNT 676
Query: 259 SFADIFLTPNK----TPQPPPPSPPMKLELKIAISEAEQSGAAEGTASVSPRPPIRQWRT 314
TP + TP+ P P+ P + + G A T P P +
Sbjct: 677 PKEPAPTTPKEPAPTTPKEPAPTTPKET------APTTPKGTAPTTLK-EPAPTTPKKPA 729
Query: 315 QDHNTPALLPKPSLGRSYSCPDLGPPGP-GTCTWPPAPPQPSRPRPRRHTVGGGEMAR-- 371
P +P+ S +C P P GT P P P+ P+ T G
Sbjct: 730 PKELAPTTTKEPT---STTCDKPAPTTPKGTAPTTPKEPAPTTPKEPAPTTPKGTAPTTL 786
Query: 372 ---APPPPRPCLRKEVFPLGGVGASPSLTTSCSSTASTSFSEPAEPRLGSTKGKEPRASK 428
AP P+ KE+ P G P+ TTS +T P E + K P K
Sbjct: 787 KEPAPTTPKKPAPKELAPTTTKG--PTSTTSDKPAPTT----PKETAPTTPKEPAPTTPK 840
Query: 429 DQVLSEPET--KTMGKVSRFRIRRTP---------ARPQLNLTPMGLPRPIRLNKKE 474
+ PET T +VS + P + P+L+ P P+ + + KE
Sbjct: 841 KPAPTTPETPPPTTSEVSTPTTTKEPTTIHKSPDESTPELSAEP--TPKALENSPKE 895
Score = 32.3 bits (72), Expect = 1.2
Identities = 36/157 (22%), Positives = 53/157 (33%), Gaps = 12/157 (7%)
Query: 355 SRPRPRRHTVGGGEMARAPPPPRPCLRKEVFPLGGVGASPSLTTSCSSTASTSFSEPAEP 414
++P P+ T G P P P KE P P+ TT S+ + P
Sbjct: 329 AKPTPKAETTTKGPALTTPKEPTPTTPKE--PASTTPKEPTPTTIKSAPTTPKEPAPTTT 386
Query: 415 RLGSTKGKEPRASKDQ-----VLSEPETKTMGKVSRFRIRRTPARPQLNLTPMGLPRPIR 469
+ T KEP + + EP T + + + P P+ P +P
Sbjct: 387 KSAPTTPKEPAPTTTKEPAPTTPKEPAPTTTKEPAPTTTKSAPTTPK-EPAPTTPKKPAP 445
Query: 470 LNKKE----FSLEEIYTNKNYQSPTTRRTFETIFEEP 502
KE E T +PTT+ T +EP
Sbjct: 446 TTPKEPAPTTPKEPTPTTPKEPAPTTKEPAPTTPKEP 482
>gi|7662046 myeloid/lymphoid or mixed-lineage leukemia 4 [Homo
sapiens]
Length = 2715
Score = 62.4 bits (150), Expect = 1e-09
Identities = 80/304 (26%), Positives = 97/304 (31%), Gaps = 33/304 (10%)
Query: 66 PVVPSKQTSIPQHHSYHQDPVHRQPPA-SPPRQAGWSSQARPPDPL--CLCREPLSRIHR 122
P +P TS P P PP SPP Q P P+ C R
Sbjct: 415 PPLPPPSTSPPPPLCPPPPPPVSPPPLPSPPPPPAQEEQEESPPPVVPATCSRKRGRPPL 474
Query: 123 TSSTLRRRSRTTPGPEEGPSQKVDRAPQPTLVVMLEDIASPRPPAEGFIDETPNFIIPAQ 182
T S R GP EG S P ED + P + F+ FI+P
Sbjct: 475 TPSQRAEREAARAGP-EGTSPPTP-TPSTATGGPPEDSPTVAPKSTTFLKNIRQFIMPVV 532
Query: 183 RAEPMRIVRQPTPPPGDLEPPFQPSALPADPLESPPTAPDPALELPSTPPPSSLLRPRLS 242
A R+++ TP E P +P + P+ PP P + P PS P
Sbjct: 533 SARSSRVIK--TPRRFMDEDPPKPPKVEVSPVLRPPITTSPPVPQEPAPVPSPPRAP-TP 589
Query: 243 PWGLAPLFRSVRSKLE--SFADIFLTPNKTPQPPPPSPPMKLELKIAISEAEQSGAAEGT 300
P PL RS L +F LT P PP P PP
Sbjct: 590 PSTPVPLPEKRRSILREPTFRWTSLTRELPPPPPAPPPP-------------------PA 630
Query: 301 ASVSPRPPIRQWRTQDHNTPALLPKPSLGRSYSC----PDLGPPGPGTCTWPPAPPQPSR 356
S P P R P P + + Y P LG P PPA P+
Sbjct: 631 PSPPPAPATSSRRPLLLRAPQFTPSEAHLKIYESVLTPPPLGAPEAPEPEPPPADDSPAE 690
Query: 357 PRPR 360
P PR
Sbjct: 691 PEPR 694
Score = 51.6 bits (122), Expect = 2e-06
Identities = 86/357 (24%), Positives = 122/357 (34%), Gaps = 45/357 (12%)
Query: 143 QKVDRAPQPTLVVMLEDIASPRPPAEGFIDETPNFIIPAQRAEPMRIVRQPTPPPGDLEP 202
+K +RA ++ E + PP P PA P +PPP P
Sbjct: 380 EKEERAVAEEMMPAAEKEEAKLPP--------PPLTPPAPSPPPPLPPPSTSPPPPLCPP 431
Query: 203 PFQPSALPADPLESPPTAPDPALELPSTPPPSSLLRPRLSPWGLAPLFRSVRSKLESFAD 262
P P + P P PP A + E P P++ R R P L P R+ R + +
Sbjct: 432 PPPPVSPPPLPSPPPPPAQEEQEESPPPVVPATCSRKRGRP-PLTPSQRAEREAARAGPE 490
Query: 263 IFLTPNKTPQ-----PPPPSPPMKLELKIAISEAEQ--SGAAEGTASVSPRPPIRQWRTQ 315
P TP PP SP + + + Q +S + P R
Sbjct: 491 GTSPPTPTPSTATGGPPEDSPTVAPKSTTFLKNIRQFIMPVVSARSSRVIKTPRRFMDED 550
Query: 316 DHNTPALLPKPSLGRSYSCPDLGPPGPGTCTWPP-APPQPSRPRP---------RRHTVG 365
P + P L + P P PP AP PS P P R T
Sbjct: 551 PPKPPKVEVSPVLRPPITTSPPVPQEPAPVPSPPRAPTPPSTPVPLPEKRRSILREPTFR 610
Query: 366 GGEMAR--APPPPRPCLRKEVFPLGGVGAS---PSLTTSCSSTASTSFSEPAE-----PR 415
+ R PPPP P P S P L + T S + + E P
Sbjct: 611 WTSLTRELPPPPPAPPPPPAPSPPPAPATSSRRPLLLRAPQFTPSEAHLKIYESVLTPPP 670
Query: 416 LGSTKGKEPR-ASKDQVLSEPETKTMGKVSRFRIRR------TPARPQLNLTPMGLP 465
LG+ + EP D +EPE + +G+ + + R TP + + ++P G P
Sbjct: 671 LGAPEAPEPEPPPADDSPAEPEPRAVGRTNHLSLPRFAPVVTTPVKAE--VSPHGAP 725
Score = 46.6 bits (109), Expect = 6e-05
Identities = 74/293 (25%), Positives = 99/293 (33%), Gaps = 51/293 (17%)
Query: 287 AISEAEQSGAAEGTASVSPRPPIRQWRTQDHNTPALLPKPSLGRSYSCPDLGPPGPGTCT 346
A++E E AAE + P PP+ + P LP PS P L PP P +
Sbjct: 385 AVAE-EMMPAAEKEEAKLPPPPLTP---PAPSPPPPLPPPSTSPP---PPLCPPPPPPVS 437
Query: 347 WPPAPPQPSRPRPRRHTVGGGEMARAPPP--PRPCLRKEVFP--------------LGGV 390
PP P P P E +PPP P C RK P G
Sbjct: 438 PPPLPSPPPPPAQE-------EQEESPPPVVPATCSRKRGRPPLTPSQRAEREAARAGPE 490
Query: 391 GASPSLTTSCSSTASTSFSEPAEPRLGSTKGKEPRASKDQVLSEPETKTMGKVSRFRIRR 450
G SP T ++T P +T K R V+S ++ + RF
Sbjct: 491 GTSPPTPTPSTATGGPPEDSPTVAPKSTTFLKNIRQFIMPVVSARSSRVIKTPRRFMDED 550
Query: 451 TPARPQLNLTPMGLPRPIRLNKKEFSLEEIYTNKNYQSPTTRRTFETIFEEPRERNGTLI 510
P P++ ++P + RP E ++PT T + P +R
Sbjct: 551 PPKPPKVEVSP--VLRPPITTSPPVPQEPAPVPSPPRAPTPPSTPVPL---PEKR----- 600
Query: 511 FTSSRKLRRAVEFRDSSLPRSRRPSRGVRAAGGRTVPPNVAPSPDVGPLLQQR 563
R + R FR +SL R P PP APSP P R
Sbjct: 601 ----RSILREPTFRWTSLTRELPPP-------PPAPPPPPAPSPPPAPATSSR 642
Score = 46.6 bits (109), Expect = 6e-05
Identities = 106/450 (23%), Positives = 159/450 (35%), Gaps = 96/450 (21%)
Query: 6 DSSPPGQPRLCRQPLTRALWGARSPKRPRLQLPGAPSPLEKASRRVLAVVLEDVMAVHMV 65
D PP P++ P+ R P +P P+P+ R
Sbjct: 548 DEDPPKPPKVEVSPVLRPPITTSPP------VPQEPAPVPSPPR---------APTPPST 592
Query: 66 PV-VPSKQTSIPQHHSYHQDPVHRQPPASPPRQAGWSSQARPPDPLCLCREPL----SRI 120
PV +P K+ SI + ++ + R+ P PP + + PP P R PL +
Sbjct: 593 PVPLPEKRRSILREPTFRWTSLTRELPPPPPAPPPPPAPSPPPAPATSSRRPLLLRAPQF 652
Query: 121 HRTSSTLR-RRSRTTPGPEEGPSQKVDRAPQPTLVVMLEDIASPRPPAEGFIDETPNFII 179
+ + L+ S TP P P AP+P + A P P A G T + +
Sbjct: 653 TPSEAHLKIYESVLTPPPLGAP-----EAPEPEPPPADDSPAEPEPRAVG---RTNHLSL 704
Query: 180 PAQRAEPMRIVRQPTPPPGDLEPPFQPSALPADPLESPPTAPDPALE---LP-STPPPSS 235
P R P+ TP ++ P P+ ++ P AL+ LP + PPP
Sbjct: 705 P--RFAPV----VTTPVKAEVSPHGAPALSNGPQTQAQLLQPLQALQTQLLPQALPPPQP 758
Query: 236 LLRPRLSPWGLAPLFRS---------------------VRSKLESFADIFLTPNKTPQPP 274
L+P SP + PL ++ R+K++ F K
Sbjct: 759 QLQPPPSPQQMPPLEKARIAGVGSLPLSGVEEKMFSLLKRAKVQLFKIDQQQQQKVAASM 818
Query: 275 PPSPPMKLELKIAISEAEQSGAAEGTASVSPRPPIRQWRTQDHNTPALLPKPSLGRSYSC 334
P SP ++E E +GA + +S R P+ R++D + A +PS S
Sbjct: 819 PLSPGGQME--------EVAGAVK---QISDRGPV---RSEDESVEAKRERPSGPES--- 861
Query: 335 PDLGPPGPGTCTWPPAPPQPSRPRPRRHTVGGGEMARAPPPPRPCLRKEVFPLGGVGASP 394
P GP C RH ARA P R PL
Sbjct: 862 PVQGPRIKHVC---------------RHAAVALGQARA-MVPEDVPRLSALPLRD---RQ 902
Query: 395 SLTTSCSSTASTSFSEPAEPRLGSTKGKEP 424
L T +S+AS + S P+ R G + P
Sbjct: 903 DLATEDTSSASETESVPSRSRRGKVEAAGP 932
Score = 40.0 bits (92), Expect = 0.006
Identities = 128/534 (23%), Positives = 165/534 (30%), Gaps = 116/534 (21%)
Query: 7 SSPPGQPRLCR---------QPLTRALWGARSPKRPRLQLPGAPSPLEKASRRVLAVVLE 57
S+PP PR P R L G P PG+PS L
Sbjct: 1851 SAPPPAPRSFSGARIKVPNYSPSRRPLGGVSFGPLPS---PGSPSSL------------- 1894
Query: 58 DVMAVHMVPVVPSKQTSIPQHHSYHQDPVHRQPP----ASPPRQAGWSSQARPPDPLCLC 113
H +P V P S P+ +PP ASPP + S Q R P P +
Sbjct: 1895 ----THHIPTVGDPDFPAPPRRSRRPSPLAPRPPPSRWASPPLKT--SPQLRVPPPTSV- 1947
Query: 114 REPLSRIHRTSSTLRRRSRTTPGPEEGPSQKVDRAPQPTLVVMLE-------DIASPRPP 166
++ + TS L PGP P D P + ++ D A+
Sbjct: 1948 ---VTALTPTSGEL-----APPGPAPSPPPPEDLGPDFEDMEVVSGLSAADLDFAASLLG 1999
Query: 167 AEGFIDET------------PNFIIPAQRAEPMRIVRQPTP---PPGDLEPPFQPSALPA 211
E F +E P + + R + P PG L P P A
Sbjct: 2000 TEPFQEEIVAAGAMGSSHGGPGDSSEEESSPTSRYIHFPVTVVSAPG-LAPSATPGAPRI 2058
Query: 212 DPLESPPTAPDPALELPSTP-----PPSSLLRPRLSPWGLAPLFRSVRSKLESFADIFLT 266
+ L+ D E P PPS R G A L S F+
Sbjct: 2059 EQLDGVDDGTDSEAEAVQQPRGQGTPPSGPGVVRAGVLGAAGDRARPPEDLPSEIVDFVL 2118
Query: 267 PNKTPQPPPPSPPMKLELKIAISEAEQSGAAEGTASVSPRPPIRQW---------RTQDH 317
N + P + L A A S ++G + SP P R + R
Sbjct: 2119 KNLGGPGDGGAGPREESLPPAPPLANGSQPSQGLTA-SPADPTRTFAWLPGAPGVRVLSL 2177
Query: 318 NTPALLPKPSLGRSYSCPDLGP----------PGPGTCTWPPAPPQPSRPRPRRHTVGGG 367
PKP+ + LG P P PP PP S P T+ G
Sbjct: 2178 GPAPEPPKPATSKIILVNKLGQVFVKMAGEGEPVPPPVKQPPLPPTISPTAPTSWTLPPG 2237
Query: 368 EM----------ARAPPPPRPCLRKEVFPLGGVGASPSLTTSCSSTAST--SFSEPAEPR 415
+ APPPP P L L ASP ST S PA P
Sbjct: 2238 PLLGVLPVVGVVRPAPPPPPPPL---TLVLSSGPASPPRQAIRVKRVSTFSGRSPPAPPP 2294
Query: 416 LGSTKGKEPRASKDQVLSE--PETKTMGK--VSRFRIRRTPARPQLNLTPMGLP 465
K PR +D SE P+ +G SR R++ R L+L G P
Sbjct: 2295 Y-----KAPRLDEDGEASEDTPQVPGLGSGGFSRVRMKTPTVRGVLDLDRPGEP 2343
Score = 33.9 bits (76), Expect = 0.43
Identities = 65/245 (26%), Positives = 78/245 (31%), Gaps = 76/245 (31%)
Query: 192 QPTPPPGDLEPPFQPSALPADPLESPPTAPDPALELPSTPPPSSLLRPRLSPWGLAPLFR 251
+P PPP +PP P+ P P T PP LL G+ P+
Sbjct: 2209 EPVPPPVK-QPPLPPTISPTAPTSW-------------TLPPGPLL-------GVLPVVG 2247
Query: 252 SVRSKLESFADIFLTPNKTPQPPPPSPPMKLELKIAISEAEQSGAAEGTASVSPRPPIRQ 311
VR P PPPP PP+ L L + G AS PR IR
Sbjct: 2248 VVR----------------PAPPPPPPPLTLVL------------SSGPAS-PPRQAIRV 2278
Query: 312 WRTQDHNTPALLPKPSLGRSYSCPDLGPPGPGTCTWPPAPPQP----SRPRPRRHTVGG- 366
R + + P Y P L G + P P SR R + TV G
Sbjct: 2279 KRVSTFSGRS----PPAPPPYKAPRLDEDGEASEDTPQVPGLGSGGFSRVRMKTPTVRGV 2334
Query: 367 ------GEMARAPPPPRPCLRKEVFPLGGVG------ASPSLTTSC-----SSTASTSFS 409
GE A P R + PL G P L S AS+S
Sbjct: 2335 LDLDRPGEPAGEESPGPLQERSPLLPLPEDGPPQVPDGPPDLLLESQWHHYSGEASSSEE 2394
Query: 410 EPAEP 414
EP P
Sbjct: 2395 EPPSP 2399
>gi|116284398 WAS/WASL interacting protein family, member 1 [Homo
sapiens]
Length = 503
Score = 62.0 bits (149), Expect = 1e-09
Identities = 99/369 (26%), Positives = 131/369 (35%), Gaps = 83/369 (22%)
Query: 89 QPPASPPRQAGWSSQARP-PDPLCLCREPL-SRIHRTSSTLRRRSRTTPGPEEGPSQKVD 146
+PP PP G S+ A+P P R P+ S HR+ +R+R P P K D
Sbjct: 125 RPPLLPP--GGRSTSAKPFSPPSGPGRFPVPSPGHRSGPPEPQRNRMPP-PRPDVGSKPD 181
Query: 147 RAPQPTLVVMLEDIASPRPPAEGFIDETP-NFIIPAQRAEPMRIVRQPTPPP--GDLEPP 203
P P ++PRP I +P N P P + PTPPP G+
Sbjct: 182 SIPPPVP-------STPRP-----IQSSPHNRGSPPVPGGPRQPSPGPTPPPFPGNRGTA 229
Query: 204 FQPSALPADPLES-------PPTAPDPALEL---PSTPPPSSLLRPRLSPWGLAPLFRSV 253
++ PL S PP P P+ L P PPP RP + + P
Sbjct: 230 LGGGSIRQSPLSSSSPFSNRPPLPPTPSRALDDKPPPPPPPVGNRPSIHREAVPP----- 284
Query: 254 RSKLESFADIFLTPNKTPQPPPPSPPMKLELKIAISEAEQSGAAEGTASVSPRPPIRQWR 313
P + +PP PS P S + Q+ S PP+
Sbjct: 285 ------------PPPQNNKPPVPSTPRP-------SASSQAPPPPPPPSRPGPPPLPPSS 325
Query: 314 TQDHNTPALLPKPSLGRSYSCPDLGPPGPGTCTWPPAPPQPS-RPRPRRHTVGGGEMARA 372
+ + TP L P+ +L S S P L PG P PP PS RP P G
Sbjct: 326 SGNDETPRL-PQRNLSLSSSTPPLPSPGRSG----PLPPPPSERPPPPVRDPPGRSGPLP 380
Query: 373 PPPPRPCLRKEVFPLGGVGASPSLTTSCSSTASTSFSEPAEPRLGSTKGKEPRASKDQVL 432
PPPP S STS + PA P+L S G + S +
Sbjct: 381 PPPP-----------------------VSRNGSTSRALPATPQLPSRSGVDSPRSGPRPP 417
Query: 433 SEPETKTMG 441
P+ + G
Sbjct: 418 LPPDRPSAG 426
Score = 56.6 bits (135), Expect = 6e-08
Identities = 78/311 (25%), Positives = 108/311 (34%), Gaps = 60/311 (19%)
Query: 76 PQHHSYHQDPVHRQPPASPPRQAGWSSQARPPDPLCLCREPLSRIHRTSSTLRRRSRTTP 135
P H S +P + P PPR S P P+ P+ SS R S P
Sbjct: 155 PGHRSGPPEPQRNRMP--PPRPDVGSKPDSIPPPVPSTPRPIQ-----SSPHNRGSPPVP 207
Query: 136 G----PEEGPSQ--------------KVDRAPQPTLVVMLEDIASPRPPAEGFIDETPNF 177
G P GP+ + ++P + P P+ D+ P
Sbjct: 208 GGPRQPSPGPTPPPFPGNRGTALGGGSIRQSPLSSSSPFSNRPPLPPTPSRALDDKPPPP 267
Query: 178 IIPAQRAEPMRIVRQPTPPPGDLEPPFQPSALPADPLESPPTAPDPALELPSTPPPSSL- 236
P + P PPP + +PP + P+ ++PP P P+ P PPSS
Sbjct: 268 PPPVGNRPSIHREAVPPPPPQNNKPPVPSTPRPSASSQAPPPPPPPSRPGPPPLPPSSSG 327
Query: 237 --LRPRLSPWGLAPLFRSVRSKLESFADIFLTPNKT-PQPPPPS----PPMKLELKIAIS 289
PRL L+ L S +P ++ P PPPPS PP++
Sbjct: 328 NDETPRLPQRNLS---------LSSSTPPLPSPGRSGPLPPPPSERPPPPVR-------D 371
Query: 290 EAEQSGAAEGTASVSPRPPIRQWRTQDHNTPALLPKPSLG-----RSYSCPDLGPPGPGT 344
+SG + P PP+ + + PA PS RS P L P P
Sbjct: 372 PPGRSG------PLPPPPPVSRNGSTSRALPATPQLPSRSGVDSPRSGPRPPLPPDRPSA 425
Query: 345 CTWPPAPPQPS 355
PP PP S
Sbjct: 426 GAPPPPPPSTS 436
Score = 36.2 bits (82), Expect = 0.086
Identities = 51/214 (23%), Positives = 74/214 (34%), Gaps = 44/214 (20%)
Query: 271 PQPPPPSPPMKLELKIA------ISEAEQSGAAEGTASVSPRPPIRQWRTQDHNTPALLP 324
P PPPP+PP +A +++ EQ+G + +S +++ T D + P +L
Sbjct: 2 PVPPPPAPPPPPTFALANTEKPTLNKTEQAGRNALLSDISKGKKLKKTVTNDRSAP-ILD 60
Query: 325 KP----------SLGRSYSCPDLGPPGPGTCTWPPAPPQPSRPRPRRHTVGGGEMARAPP 374
KP G G G G PP G G + +A
Sbjct: 61 KPKGAGAGGGGGGFGGGGGFGGGGGGGGGGSFGGGGPP------------GLGGLFQAGM 108
Query: 375 PPRPCLRKEVFPLGGVGASPSLTTSCSSTASTSFSEPAEPRLGSTKGKEPRASKDQVLSE 434
P GG P L ST++ FS P+ P G+ P S
Sbjct: 109 PKLRSTANRDNDSGG-SRPPLLPPGGRSTSAKPFSPPSGP------GRFPVPSPGHRSGP 161
Query: 435 PETKTMGKVSRFRIRRTPARPQLNLTPMGLPRPI 468
PE + R R P RP + P +P P+
Sbjct: 162 PEPQ--------RNRMPPPRPDVGSKPDSIPPPV 187
>gi|38373695 WAS/WASL interacting protein family, member 1 [Homo
sapiens]
Length = 503
Score = 62.0 bits (149), Expect = 1e-09
Identities = 99/369 (26%), Positives = 131/369 (35%), Gaps = 83/369 (22%)
Query: 89 QPPASPPRQAGWSSQARP-PDPLCLCREPL-SRIHRTSSTLRRRSRTTPGPEEGPSQKVD 146
+PP PP G S+ A+P P R P+ S HR+ +R+R P P K D
Sbjct: 125 RPPLLPP--GGRSTSAKPFSPPSGPGRFPVPSPGHRSGPPEPQRNRMPP-PRPDVGSKPD 181
Query: 147 RAPQPTLVVMLEDIASPRPPAEGFIDETP-NFIIPAQRAEPMRIVRQPTPPP--GDLEPP 203
P P ++PRP I +P N P P + PTPPP G+
Sbjct: 182 SIPPPVP-------STPRP-----IQSSPHNRGSPPVPGGPRQPSPGPTPPPFPGNRGTA 229
Query: 204 FQPSALPADPLES-------PPTAPDPALEL---PSTPPPSSLLRPRLSPWGLAPLFRSV 253
++ PL S PP P P+ L P PPP RP + + P
Sbjct: 230 LGGGSIRQSPLSSSSPFSNRPPLPPTPSRALDDKPPPPPPPVGNRPSIHREAVPP----- 284
Query: 254 RSKLESFADIFLTPNKTPQPPPPSPPMKLELKIAISEAEQSGAAEGTASVSPRPPIRQWR 313
P + +PP PS P S + Q+ S PP+
Sbjct: 285 ------------PPPQNNKPPVPSTPRP-------SASSQAPPPPPPPSRPGPPPLPPSS 325
Query: 314 TQDHNTPALLPKPSLGRSYSCPDLGPPGPGTCTWPPAPPQPS-RPRPRRHTVGGGEMARA 372
+ + TP L P+ +L S S P L PG P PP PS RP P G
Sbjct: 326 SGNDETPRL-PQRNLSLSSSTPPLPSPGRSG----PLPPPPSERPPPPVRDPPGRSGPLP 380
Query: 373 PPPPRPCLRKEVFPLGGVGASPSLTTSCSSTASTSFSEPAEPRLGSTKGKEPRASKDQVL 432
PPPP S STS + PA P+L S G + S +
Sbjct: 381 PPPP-----------------------VSRNGSTSRALPATPQLPSRSGVDSPRSGPRPP 417
Query: 433 SEPETKTMG 441
P+ + G
Sbjct: 418 LPPDRPSAG 426
Score = 56.6 bits (135), Expect = 6e-08
Identities = 78/311 (25%), Positives = 108/311 (34%), Gaps = 60/311 (19%)
Query: 76 PQHHSYHQDPVHRQPPASPPRQAGWSSQARPPDPLCLCREPLSRIHRTSSTLRRRSRTTP 135
P H S +P + P PPR S P P+ P+ SS R S P
Sbjct: 155 PGHRSGPPEPQRNRMP--PPRPDVGSKPDSIPPPVPSTPRPIQ-----SSPHNRGSPPVP 207
Query: 136 G----PEEGPSQ--------------KVDRAPQPTLVVMLEDIASPRPPAEGFIDETPNF 177
G P GP+ + ++P + P P+ D+ P
Sbjct: 208 GGPRQPSPGPTPPPFPGNRGTALGGGSIRQSPLSSSSPFSNRPPLPPTPSRALDDKPPPP 267
Query: 178 IIPAQRAEPMRIVRQPTPPPGDLEPPFQPSALPADPLESPPTAPDPALELPSTPPPSSL- 236
P + P PPP + +PP + P+ ++PP P P+ P PPSS
Sbjct: 268 PPPVGNRPSIHREAVPPPPPQNNKPPVPSTPRPSASSQAPPPPPPPSRPGPPPLPPSSSG 327
Query: 237 --LRPRLSPWGLAPLFRSVRSKLESFADIFLTPNKT-PQPPPPS----PPMKLELKIAIS 289
PRL L+ L S +P ++ P PPPPS PP++
Sbjct: 328 NDETPRLPQRNLS---------LSSSTPPLPSPGRSGPLPPPPSERPPPPVR-------D 371
Query: 290 EAEQSGAAEGTASVSPRPPIRQWRTQDHNTPALLPKPSLG-----RSYSCPDLGPPGPGT 344
+SG + P PP+ + + PA PS RS P L P P
Sbjct: 372 PPGRSG------PLPPPPPVSRNGSTSRALPATPQLPSRSGVDSPRSGPRPPLPPDRPSA 425
Query: 345 CTWPPAPPQPS 355
PP PP S
Sbjct: 426 GAPPPPPPSTS 436
Score = 36.2 bits (82), Expect = 0.086
Identities = 51/214 (23%), Positives = 74/214 (34%), Gaps = 44/214 (20%)
Query: 271 PQPPPPSPPMKLELKIA------ISEAEQSGAAEGTASVSPRPPIRQWRTQDHNTPALLP 324
P PPPP+PP +A +++ EQ+G + +S +++ T D + P +L
Sbjct: 2 PVPPPPAPPPPPTFALANTEKPTLNKTEQAGRNALLSDISKGKKLKKTVTNDRSAP-ILD 60
Query: 325 KP----------SLGRSYSCPDLGPPGPGTCTWPPAPPQPSRPRPRRHTVGGGEMARAPP 374
KP G G G G PP G G + +A
Sbjct: 61 KPKGAGAGGGGGGFGGGGGFGGGGGGGGGGSFGGGGPP------------GLGGLFQAGM 108
Query: 375 PPRPCLRKEVFPLGGVGASPSLTTSCSSTASTSFSEPAEPRLGSTKGKEPRASKDQVLSE 434
P GG P L ST++ FS P+ P G+ P S
Sbjct: 109 PKLRSTANRDNDSGG-SRPPLLPPGGRSTSAKPFSPPSGP------GRFPVPSPGHRSGP 161
Query: 435 PETKTMGKVSRFRIRRTPARPQLNLTPMGLPRPI 468
PE + R R P RP + P +P P+
Sbjct: 162 PEPQ--------RNRMPPPRPDVGSKPDSIPPPV 187
>gi|224451135 splicing factor, arginine/serine-rich 15 isoform 3
[Homo sapiens]
Length = 1125
Score = 62.0 bits (149), Expect = 1e-09
Identities = 101/391 (25%), Positives = 136/391 (34%), Gaps = 87/391 (22%)
Query: 133 TTPGPEEGPSQKVDRAPQPTLVVMLEDIASPRPPAEGFIDETPNFIIPAQRAEPMRIVRQ 192
T P P+ P Q P P +V L+ PPA TP IP P V
Sbjct: 676 TVPPPQVPPHQ-----PGPPVVGALQ------PPAF-----TPPLGIPPPGFGPG--VPP 717
Query: 193 PTPPPGDLEPPFQPSALPADPLESPPTAPDPALELPSTPPPSSLLRPRLSPWGLAPLFRS 252
P PPP L P F P LP P PP P P PP S+ P P + L
Sbjct: 718 PPPPPPFLRPGFNPMHLP--PGFLPPGPP------PPITPPVSIPPPHTPPISIPNLVSG 769
Query: 253 VRSKLESFADIFLTPNKTPQPPP---PSPPMKLELKIAISEAEQSGAAEGTASVSPRPPI 309
R ES + + + P P P+PP+ + + GT V+P P I
Sbjct: 770 ARGNAESGDSVKMYGSAVPPAAPTNLPTPPVTQPVSLL-----------GTQGVAPGPVI 818
Query: 310 RQWRTQDHNTPALLPKPSLGRSYSCPDLGPPGPGTCTWPPAPPQPSRPR--PRRHTVGGG 367
Q +T L +P L P G P P +P PP+P P R G G
Sbjct: 819 ---GLQAPSTGLLGARPGLIPLQRPP--GMPPPHLQRFPLMPPRPMPPHMMHRGPPPGPG 873
Query: 368 EMARAP--------PPPRPCLRKEVFP-LGGVGASPSLTTSCSSTASTSFSEPAEPRLGS 418
A P PP P +R P LGG G P
Sbjct: 874 GFAMPPPHGMKGPFPPHGPFVRPGGMPGLGGPGPGPG----------------------- 910
Query: 419 TKGKEPRASKDQVLSEPETKTMGKVSRFRIRRTPARPQLNLTPMGLPRPIRLNKKEFSLE 478
G E R + Q +P+ + + + ++ +P P P P + ++F +
Sbjct: 911 --GPEDRDGRQQPPQQPQQQPQPQAPQQPQQQQQQQP----PPSQQPPPTQQQPQQFRND 964
Query: 479 --EIYTNKNYQSPTTRRTFETIFEEPRERNG 507
+ + + Q RR+F E RER G
Sbjct: 965 NRQQFNSGRDQERFGRRSFGNRVENDRERYG 995
>gi|239752594 PREDICTED: hypothetical protein, partial [Homo
sapiens]
Length = 673
Score = 61.6 bits (148), Expect = 2e-09
Identities = 123/485 (25%), Positives = 174/485 (35%), Gaps = 74/485 (15%)
Query: 15 LCRQPLTRALWGARSPKRPRLQLPGAPSPLEKASRRVLAVVLEDVMAVHMVPVVPSKQTS 74
L R+P T +L RSP R L + + L A+ + ++ P S T
Sbjct: 112 LMRRPSTASL--TRSPSRASLTTTPSRASLSMTPSTAAALTMPSRASLTRTPPRASL-TM 168
Query: 75 IPQHHSYHQDPVHRQPPASPPRQA--GWSSQARPPDPLCLCREPLSRIHRTSSTLRRRSR 132
P S + P P P R + G S A L+++ T+S R SR
Sbjct: 169 TPSTASLTRTPPRASPTGMPSRTSPTGMPSTAS-----------LTKMDSTASITRTLSR 217
Query: 133 TTPGPEEGPSQKVDRAPQPTLVVMLEDIASPRPPAEGFIDETPNFIIPAQRAEPMRIVRQ 192
+P + P+ +L +M P+ + TP RA P ++ +
Sbjct: 218 ASPTGTPPRASPTGSPPRASLSMM---------PSTALLIRTP------PRASPTGMLSR 262
Query: 193 PTPPPGDLEPPFQPSALPADPLESPPTAPDPALELPSTPPPSSLLR--PRLSPWGLAPLF 250
+ D + P+ P + PT L TP +SL+R PR SP G+ L
Sbjct: 263 TSLTKMDSTASI--TRTPSRPSTASPTGTPSRASLSMTPSTASLMRMLPRASPTGM--LS 318
Query: 251 RSVRSKLESFADIFLTPNK------------TPQPPPPSP---PMKLELKIAISEAEQSG 295
R+ +K++S A I TP + T +P SP P + + S A +G
Sbjct: 319 RTSLTKMDSTASISRTPPRASITRTPSRASPTGKPSTASPTGTPSRASPTGSPSTASLTG 378
Query: 296 AAEGTASVSPRPPIRQWRTQDHNTPALLPKPS-------LGR-------SYSCPDLGPPG 341
+ TAS + PP R T +T +L KP L R S + P PP
Sbjct: 379 LSS-TASPTGTPP-RASPTGTPSTASLTRKPPRASPTGMLSRTSITKMDSTASPTRTPPR 436
Query: 342 PGTCTWPP-APPQ--PSRPRPRRHTVGGGEMARAPPPPRPCLRKEVFPLGGVGASPSLTT 398
PP A P PSR P T +P P G + SLT
Sbjct: 437 ASPTGTPPRASPTGTPSRASPTG-TQSTASPTGSPSTASPTGSPSTASPTGSPSRASLTR 495
Query: 399 SCSSTASTSFSEPAE-PRLGSTKGKEPRASKDQVLSEPETK-TMGKVSRFRIRRTPARPQ 456
+ S + T A R S S P T MG SR + RTP+R
Sbjct: 496 TPSRASLTKMESTASITRTPSRASPTWTPSTASPTGSPSTALAMGSPSRAALTRTPSRAS 555
Query: 457 LNLTP 461
L TP
Sbjct: 556 LTRTP 560
Score = 39.3 bits (90), Expect = 0.010
Identities = 76/303 (25%), Positives = 101/303 (33%), Gaps = 29/303 (9%)
Query: 186 PMRIVRQPTPPPGDLEPPFQPSALPADPLESPPTAPDPALELPSTPPPSSLLR--PRLSP 243
P R TPP L+ ++L P + T + L TP +SL R PR S
Sbjct: 44 PSRASLTGTPPRASLKGTTSMASLMVSPSRASLTRMQSSSLLTRTPSMASLKRMPPRASR 103
Query: 244 WGLAPLFRSVR-------SKLESFADIFLTPNKTPQPPPPSPPMKLELKIAISEAEQSGA 296
P +R ++ S A + TP++ PS L + S
Sbjct: 104 TRTLPRASLMRRPSTASLTRSPSRASLTTTPSRASLSMTPSTAAALTMPSRASLTRTPPR 163
Query: 297 AE-----GTASVSPRPPIRQ-----WRTQDHNTPALLPKPSLGRSYSCPDLGPPGPGTCT 346
A TAS++ PP RT P+ + + S T T
Sbjct: 164 ASLTMTPSTASLTRTPPRASPTGMPSRTSPTGMPSTASLTKMDSTASITRTLSRASPTGT 223
Query: 347 WPPAPPQPSRPRPRRHTVGGGEMARAPPP---PRPCLRKEVFPLGGVGASPSLTTSCSST 403
P A P S PR + + PP P L + AS + T S ST
Sbjct: 224 PPRASPTGSPPRASLSMMPSTALLIRTPPRASPTGMLSRTSLTKMDSTASITRTPSRPST 283
Query: 404 AS-----TSFSEPAEPRLGSTKGKEPRASKDQVLSEPETKTMGKVSRFRIRRTPARPQLN 458
AS + S P S PRAS +LS M S I RTP R +
Sbjct: 284 ASPTGTPSRASLSMTPSTASLMRMLPRASPTGMLSRTSLTKMD--STASISRTPPRASIT 341
Query: 459 LTP 461
TP
Sbjct: 342 RTP 344
>gi|91718902 myeloid/lymphoid or mixed-lineage leukemia 3 [Homo
sapiens]
Length = 4911
Score = 60.8 bits (146), Expect = 3e-09
Identities = 78/328 (23%), Positives = 122/328 (37%), Gaps = 59/328 (17%)
Query: 80 SYHQDPVHRQPPASPPRQAG----WSSQARPPDPLCLCREPLSRIHRTSSTLRRRSRTTP 135
S+H++ +QPP++P + QA PP P SRI S + ++ P
Sbjct: 1824 SFHKELFTKQPPSTPTSTSSDDVFVKPQAPPPPPAP------SRIPIQDSLSQAQTSQPP 1877
Query: 136 GPEE-GPSQKVDRAPQPTLVVMLEDIASPRPPAEGFIDETPNFIIPAQRAEPMRIVRQP- 193
P+ P R P P + + + +PRPP G N P + P+ V +P
Sbjct: 1878 SPQVFSPGSSNSRPPSP-MDPYAKMVGTPRPPPVGHSFSRRNSAAPVENCTPLSSVSRPL 1936
Query: 194 ------TPPPGDLEPPFQPSALPADPLESPPTAPDPAL--ELPST--------------- 230
P + S DP PP P P + + P +
Sbjct: 1937 QMNETTANRPSPVRDLCSSSTTNNDPYAKPPDTPRPVMTDQFPKSLGLSRSPVVSEQTAK 1996
Query: 231 -PPPSSLLRPRLSPWGLAPLFRSVRSKLESFADIFLTPN---------KTPQPPPPSPPM 280
P + P A +F+ R +S+A LTP KTP PPPS
Sbjct: 1997 GPIAAGTSDHFTKPSPRADVFQRQRIP-DSYARPLLTPAPLDSGPGPFKTPMQPPPS--- 2052
Query: 281 KLELKIAISEAEQSGAAE--GTASVSPRPPIRQWRTQD---HNTPALLPKPSLGRSYSCP 335
+ ++S+A + + + +++PRP Q ++ P L P P++ S++ P
Sbjct: 2053 SQDPYGSVSQASRRLSVDPYERPALTPRPIDNFSHNQSNDPYSQPPLTPHPAVNESFAHP 2112
Query: 336 DLGPPGPGTCTWP----PAPPQPSRPRP 359
PGT + P P P PRP
Sbjct: 2113 SRAFSQPGTISRPTSQDPYSQPPGTPRP 2140
Score = 52.4 bits (124), Expect = 1e-06
Identities = 97/435 (22%), Positives = 141/435 (32%), Gaps = 87/435 (20%)
Query: 7 SSPPGQPRLCRQPLTRALWGARSPKRPRLQLPGAPSPLEKASRRVLAVVLEDVMAVHMVP 66
S PPG PR +++ ARS P Q PG P P D +
Sbjct: 2132 SQPPGTPRPVVDSYSQSSGTARSNTDPYSQPPGTPRP-----------TTVDPYSQQPQT 2180
Query: 67 VVPSKQTSI---PQHHSYHQDPVHRQPPASPPRQAGWSSQARPPDPLCLCREPLSRIHRT 123
PS QT + P + H DP + PP +P RP + + P + R
Sbjct: 2181 PRPSTQTDLFVTPVTNQRHSDP-YAHPPGTP----------RPGISVPYSQPPATPRPRI 2229
Query: 124 SSTLRRRSRTTP--GPEEGPSQKVDRAPQPTLVVMLEDIASPRPPAEGFIDETPNFIIPA 181
S R S T P P + P + + P L L RPP +TP
Sbjct: 2230 SEGFTRSSMTRPVLMPNQDPFLQAAQNRGPALPGPL-----VRPP--DTCSQTP------ 2276
Query: 182 QRAEPMRIVRQPTPPPGDLEPPFQPSALPADPLESPPTAPDPALELPSTPPPSSLLRPRL 241
R P P D PSA DP + P P + T + + +
Sbjct: 2277 ---------RPPGPGLSDTFSRVSPSA-ARDPYDQSPMTPRSQSDSFGTSQTAHDVADQP 2326
Query: 242 SPWGLAPLFRSVRSKLESFADIFLTPNKTPQPPPPSPPMKLELKIAISEAE--------- 292
P S S + S F ++ P P P S + + +++A+
Sbjct: 2327 RPGSEGSFCASSNSPMHSQGQQFSGVSQLPGPVPTSGVTDTQNTVNMAQADTEKLRQRQK 2386
Query: 293 -----------------QSGAAEGTASVSPRPPIRQWRTQDHNTPALLPKPSLGRSYSCP 335
Q ++ + +V P++ W+ ++ N P P + P
Sbjct: 2387 LREIILQQQQQKKIAGRQEKGSQDSPAVPHPGPLQHWQPENVNQAFTRPPPPYPGNIRSP 2446
Query: 336 DLGPPGPGTCTWP-----PAPPQPS----RPRPRRHTVGGGEMARAPPPPRPCLRKEVFP 386
P GP +P P PP + RP R GG P R + +
Sbjct: 2447 VAPPLGPRYAVFPKDQRGPYPPDVASMGMRPHGFRFGFPGGSHGTMPSQERFLVPPQ--Q 2504
Query: 387 LGGVGASPSLTTSCS 401
+ G G SP L S S
Sbjct: 2505 IQGSGVSPQLRRSVS 2519
Score = 35.0 bits (79), Expect = 0.19
Identities = 42/175 (24%), Positives = 74/175 (42%), Gaps = 32/175 (18%)
Query: 262 DIFLTPNKTPQPPPPSPPMKLELKIAISEAEQSGA------AEGTASVSPRPPIRQWRTQ 315
D+F+ P PPPP P ++ ++ ++S+A+ S + G+++ P P+ +
Sbjct: 1845 DVFVKPQA---PPPPPAPSRIPIQDSLSQAQTSQPPSPQVFSPGSSNSRPPSPMDPYAKM 1901
Query: 316 DHNTPALLPKPSLGRSYSCPDLGPPGPGTCTWPPAPPQP--------SRPRPRRH----- 362
TP P +G S+S + P CT + +P +RP P R
Sbjct: 1902 V-GTPR---PPPVGHSFSRRNSAAPVEN-CTPLSSVSRPLQMNETTANRPSPVRDLCSSS 1956
Query: 363 TVGGGEMARAPPPPRPCLRKEVFPLGGVGASPSLTTSCSS---TASTS--FSEPA 412
T A+ P PRP + + G+ SP ++ + A TS F++P+
Sbjct: 1957 TTNNDPYAKPPDTPRPVMTDQFPKSLGLSRSPVVSEQTAKGPIAAGTSDHFTKPS 2011
>gi|122937496 WAS/WASL interacting protein family, member 3 [Homo
sapiens]
Length = 483
Score = 60.8 bits (146), Expect = 3e-09
Identities = 82/323 (25%), Positives = 111/323 (34%), Gaps = 89/323 (27%)
Query: 139 EGPSQKVDRAPQPTLVVMLEDIASPR-PPAEGFIDETPNFIIPAQRAEPMRIVRQPTPPP 197
+GP RAP P L + I+ P PPA + T A+ A P V P PP
Sbjct: 124 QGPGS---RAPSPRLPN--KTISGPLIPPASPRLGNTSEAHGAARTAPPRPNVPAPPPPT 178
Query: 198 GDLEPPFQPSALPAD--------------------------PLESPPTAPDPALELPSTP 231
PP P LP+ P PP P P P P
Sbjct: 179 PPPPPPPLPPPLPSSSPIKTPLVSPPGPLTKGNLPVVAPPVPCAPPPPPPPPPPTPPPLP 238
Query: 232 PPSSL----LRPRLSPWGLAPL-----------FRSVRSKLESFADIFLTPNKTPQPPPP 276
P S L ++P+L+P L P+ + ++++ S A P P PPPP
Sbjct: 239 PASVLSDKAVKPQLAPLHLPPIPPPLPLLPPCGYPGLKAEPASPAQDAQEP---PAPPPP 295
Query: 277 SPPMKLELKIAISEAEQSGAAEGTASVSPRPPIRQWRTQDHNTPALLPK-PSLGRSYSCP 335
PP A+ + P PP+ + P L PK PS
Sbjct: 296 LPPY---------------ASCSPRASLPAPPLPGVNSSSETPPPLPPKSPSF------- 333
Query: 336 DLGPPGPGTCTWPPAPPQPSRPRP----RRHTVGGGEMARAPPPPRPCLRKEVFPLGGVG 391
PP PAPP P +P +RH G + PPP P R
Sbjct: 334 -QAPPQKAGAQALPAPPAPPGSQPFLQKKRHGRPGAGGGKLNPPPAPPAR---------- 382
Query: 392 ASPSLTTSCSSTASTSFSEPAEP 414
SP+ S S +T+++ +P
Sbjct: 383 -SPTTELSSKSQQATAWTPTQQP 404
Score = 35.0 bits (79), Expect = 0.19
Identities = 59/255 (23%), Positives = 79/255 (30%), Gaps = 50/255 (19%)
Query: 29 SPKRPRLQLPGAPSPLEKASRRVLAVVLEDVMAVHMVPVVPSKQTSIPQHHSYHQDPVHR 88
+P P P P PL AS V + +H+ P+ P P + P +
Sbjct: 222 APPPPPPPPPPTPPPLPPASVLSDKAVKPQLAPLHLPPIPPPLPLLPPCGY-----PGLK 276
Query: 89 QPPASPPRQAGWSSQARPPDPLCLCREPLSRIHRTSSTLRRRSRTTPGPEEGPSQKVDRA 148
PASP + A PP PL P P +
Sbjct: 277 AEPASPAQDA--QEPPAPPPPL-----------------------PPYASCSPRASLPAP 311
Query: 149 PQPTLVVMLEDIASPRPPAEGFIDETPNFIIPAQRAEPMRIVRQPTPPPGDLEPPFQPSA 208
P P V + P PP ++P+F P Q+A + P PP PF
Sbjct: 312 PLPG-VNSSSETPPPLPP------KSPSFQAPPQKAGAQALPAPPAPPGSQ---PFLQKK 361
Query: 209 LPADP------LESPPTAP--DPALELPSTPPPSSLLRPRLSPWGLAPLFRSVRSKLESF 260
P L PP P P EL S ++ P P G L ++ F
Sbjct: 362 RHGRPGAGGGKLNPPPAPPARSPTTELSSKSQQATAWTPTQQPGG--QLRNGSLHIIDDF 419
Query: 261 ADIFLTPNKTPQPPP 275
F + PPP
Sbjct: 420 ESKFTFHSVEDFPPP 434
Score = 34.3 bits (77), Expect = 0.33
Identities = 55/216 (25%), Positives = 69/216 (31%), Gaps = 60/216 (27%)
Query: 193 PTPPPGDLEPPFQPSALPADPLESPPTAPDPALELPSTPPPS---SLLRPRLSPWGLAPL 249
P PPP PP P P PL +PP P PS PP S S LR R P G + L
Sbjct: 2 PVPPPP--PPPLPP---PPPPLGAPPPPP------PSAPPVSTDTSSLR-RADPKGRSAL 49
Query: 250 FRSVRSKLESFADIFLTPNKTPQ---------------------PPPPSPPMKLELKIAI 288
++ + PQ PP + +
Sbjct: 50 LADIQQGTRLRKVTQINDRSAPQIESSKGTNKEGGGSANTRGASTPPTLGDLFAGGFPVL 109
Query: 289 SEAEQSGAAEGTASVSP--RPPIRQWRTQDHNTPALLP-KPSLG---RSYSCPDLGPPGP 342
A Q A G P R P + + + P + P P LG ++ PP P
Sbjct: 110 RPAGQRDVAGGKTGQGPGSRAPSPRLPNKTISGPLIPPASPRLGNTSEAHGAARTAPPRP 169
Query: 343 GTCTWPPAPPQPSRPRPRRHTVGGGEMARAPPPPRP 378
PAPP P+ P PPPP P
Sbjct: 170 NV----PAPPPPTPP--------------PPPPPLP 187
>gi|150417989 cyclin K isoform 1 [Homo sapiens]
Length = 580
Score = 60.8 bits (146), Expect = 3e-09
Identities = 79/295 (26%), Positives = 111/295 (37%), Gaps = 42/295 (14%)
Query: 4 PGDSSPPGQPRLC--RQPLTRALWGARSPKRPRLQLPGAPSPLEKASRRVLAVVLEDVMA 61
P SS P QP+ +QP + A+ PK+P Q P +P +++A V++ E+ A
Sbjct: 293 PSQSSEPSQPQQKDPQQPAQQQQ-PAQQPKKPSPQ-PSSPRQVKRAV--VVSPKEENKAA 348
Query: 62 VHMVPVVPSKQTSIPQHHSYHQDPVHRQPPASPPRQAGWSSQARPPDPLCLCREPLSRIH 121
P +P +T+ P P H P PP A +A PP P+ P +I
Sbjct: 349 EPPPPKIPKIETTHPP-----LPPAHPPPDRKPPLAAALG-EAEPPGPVDATDLPKVQIP 402
Query: 122 RTSSTLRRRSRTTPGPEEGPSQKVDRAPQPTLVVMLEDIA--SPRPPAEGFID------- 172
+ P P P R P P + ++ S EG+
Sbjct: 403 PPAH---------PAPVHQPPPLPHRPPPPPPSSYMTGMSTTSSYMSGEGYQSLQSMMKT 453
Query: 173 ETPNF-IIPAQRAEPMRI-----VRQPTPPPGDLEPPFQPSALPADPLESPPTAPDPALE 226
E P++ +P P + V P PPP + PP PA P +P P P
Sbjct: 454 EGPSYGALPPAYGPPAHLPYHPHVYPPNPPPPPVPPPPASFPPPAIPPPTPGYPPPPPTY 513
Query: 227 LPSTPPPSSLLRPRLSPWGLAPLFRSVRSKL--ESFADIFLTPNKTPQPPPPSPP 279
P+ PPP PRL P P L S+ + P P PPP PP
Sbjct: 514 NPNFPPPP----PRLPPTHAVPPHPPPGLGLPPASYPPPAVPPGGQPPVPPPIPP 564
Score = 53.1 bits (126), Expect = 7e-07
Identities = 89/364 (24%), Positives = 130/364 (35%), Gaps = 89/364 (24%)
Query: 55 VLEDVMAVHMVPVVPSKQTSIPQHHSYHQDPVHRQPPASPPRQAGWSSQARPPDPLCLCR 114
VLED+ H + + S+ HH+ HQ + + P P Q Q++P
Sbjct: 246 VLEDIC--HQILDLYSQGKQQMPHHTPHQ--LQQPPSLQPTPQVPQVQQSQPSQS----S 297
Query: 115 EPLSRIHRTSSTLRRRSRTTPGPEEGPSQKVDR-APQPTLVVMLEDIASPRPPAEGFIDE 173
EP S +++ P ++ P+Q+ + +PQP+ ++ P E E
Sbjct: 298 EP--------SQPQQKDPQQPAQQQQPAQQPKKPSPQPSSPRQVKRAVVVSPKEENKAAE 349
Query: 174 TPNFIIPAQRAEPMRIVRQPTPPPGDLEPPFQPSALPADPLESPPTAPDPALELPST--P 231
P IP + E P PP D +PP L A E+ P P A +LP P
Sbjct: 350 PPPPKIP--KIETTHPPLPPAHPPPDRKPP-----LAAALGEAEPPGPVDATDLPKVQIP 402
Query: 232 PPSSLLRPRLSPWGLAPLFRSVRSKLESFADIFLTPNKTPQPPPPSPPMKLELKIAISEA 291
PP+ AP+ + P P PPP PP ++ + +
Sbjct: 403 PPAHP----------APVHQ---------------PPPLPHRPPPPPPSSYMTGMSTTSS 437
Query: 292 EQSG----------AAEGTASVSPRP---PIRQWRTQDHNTPALLPKPSL---GRSYSCP 335
SG EG + + P P H P P P + S+ P
Sbjct: 438 YMSGEGYQSLQSMMKTEGPSYGALPPAYGPPAHLPYHPHVYPPNPPPPPVPPPPASFPPP 497
Query: 336 DLGPPGPGTCTWPPAPP--QPSRPRPRRHTVGGGEMARAPPPPR--PCLRKEVFPLGGVG 391
+ PP PG +PP PP P+ P PPPPR P P G+G
Sbjct: 498 AIPPPTPG---YPPPPPTYNPNFP---------------PPPPRLPPTHAVPPHPPPGLG 539
Query: 392 ASPS 395
P+
Sbjct: 540 LPPA 543
>gi|116284392 mucin 2 precursor [Homo sapiens]
Length = 5179
Score = 60.1 bits (144), Expect = 6e-09
Identities = 74/341 (21%), Positives = 107/341 (31%), Gaps = 37/341 (10%)
Query: 133 TTPGPEEGPSQKVDRA--PQPTLVVMLEDIASPRPPAEGFIDETPNFIIPAQRAEPMRIV 190
TTP P PS + P PT +P PP T P P
Sbjct: 1446 TTPPPTTTPSPPISTTTTPPPTTTPS-PPTTTPSPPTTTPSPPTTTTTTPPPTTTPSPPT 1504
Query: 191 RQPTPPPGDLE--PPFQPSALPADPLESPP--TAPDPALELPSTPPPSSLLRPRLSPWGL 246
P PP PP + P +PP T P P P TPP S+ P +
Sbjct: 1505 TTPITPPASTTTLPPTTTPSPPTTTTTTPPPTTTPSPPTTTPITPPTSTTTLPPTTTPSP 1564
Query: 247 APLFRSVRSKLESFADIFLTPNKTPQPPPPSPPMKLELKIAISEAEQSGAAEGTASVSPR 306
P + P TP PP + P + + + T + +P
Sbjct: 1565 PPTTTTTPP-----------PTTTPSPPTTTTPSPPTITTTTPPPTTTPSPPTTTTTTPP 1613
Query: 307 P----------PIRQWRTQDHNTPALLPKPSLGRSYSCPDLGPPGPGTCTWPPAPPQPSR 356
P PI + P P P + + P P P T T P+PP +
Sbjct: 1614 PTTTPSPPTTTPITPPTSTTTLPPTTTPSPPPTTTTTPPPTTTPSPPTTT-TPSPPITTT 1672
Query: 357 PRPRRHTVGGGEMARAPPPPRPCLRKEVFPLGGVGASPSLTTSCSSTASTSFSEPAEPRL 416
P T + P PP + P S +TT+ + +++T+ S P
Sbjct: 1673 TTPPPTTTPSSPITTTPSPPTTTM---TTPSPTTTPSSPITTTTTPSSTTTPSPPPTTMT 1729
Query: 417 GSTKGKEPRASKDQVLSEPETKTMGKVSRFRIRRTPARPQL 457
+ P + + P T T ++ TP P +
Sbjct: 1730 TPSPTTTPSPPTTTMTTLPPTTTSSPLT-----TTPLPPSI 1765
Score = 52.8 bits (125), Expect = 9e-07
Identities = 71/303 (23%), Positives = 94/303 (31%), Gaps = 47/303 (15%)
Query: 133 TTPGPEEGPSQKVDRAPQPTLVVMLEDIASPRPPAEGFIDETPNFIIPAQRAEPMRIVRQ 192
TTP P +P PT L +P PP T P I
Sbjct: 1397 TTPSPPT-----TTPSPPPTSTTTLPPTTTPSPPT------TTTTTPPPTTTPSPPITTT 1445
Query: 193 PTPPPGDL-EPPFQ------PSALPADPLESPP---TAPDPALELPSTPPPSSLLRPRLS 242
TPPP PP P+ P+ P +P T P P +TPPP++ P +
Sbjct: 1446 TTPPPTTTPSPPISTTTTPPPTTTPSPPTTTPSPPTTTPSPPTTTTTTPPPTTTPSPPTT 1505
Query: 243 PWGLAPLFRSVRSKLESFADIFLTPNKTPQP-------PPPSPPMKLELKIAISEAEQSG 295
P + L P TP P PPP+ I+ +
Sbjct: 1506 TPITPPASTTT-----------LPPTTTPSPPTTTTTTPPPTTTPSPPTTTPITPPTSTT 1554
Query: 296 AAEGTASVSPRPPIRQWRTQDHNTPA----LLPKPSLGRSYSCPDLGPPGPGTCTWPPAP 351
T + SP PP TP+ P P + + P P P T T P
Sbjct: 1555 TLPPTTTPSP-PPTTTTTPPPTTTPSPPTTTTPSPPTITTTTPPPTTTPSPPTTTTTTPP 1613
Query: 352 PQPSRPRPRRHTVGGGEMARAPPP---PRPCLRKEVFPLGGVGASPSLTTSCSSTASTSF 408
P + P + PP P P P SP TT+ S +T+
Sbjct: 1614 PTTTPSPPTTTPITPPTSTTTLPPTTTPSPPPTTTTTPPPTTTPSPPTTTTPSPPITTTT 1673
Query: 409 SEP 411
+ P
Sbjct: 1674 TPP 1676
Score = 42.4 bits (98), Expect = 0.001
Identities = 61/261 (23%), Positives = 77/261 (29%), Gaps = 53/261 (20%)
Query: 133 TTPGPEEGPSQKVDRAPQPTLVVMLED--IASPRPPAEGFIDETPNF---------IIPA 181
TTP P PS P P + +P PP P I P
Sbjct: 1570 TTPPPTTTPSPPTTTTPSPPTITTTTPPPTTTPSPPTTTTTTPPPTTTPSPPTTTPITPP 1629
Query: 182 QRAEPMRIVRQPTPPPGDLEPPFQPSALPADPLESPPT--APDPALELPSTPP----PSS 235
+ P+PPP P P SPPT P P + +TPP PSS
Sbjct: 1630 TSTTTLPPTTTPSPPPTTTTTP------PPTTTPSPPTTTTPSPPITTTTTPPPTTTPSS 1683
Query: 236 LLRPRLSPWGLAPLFRSVRSKLESFADIFLTPNKTPQPPPPSPPMKLELKIAISEAEQSG 295
+ SP S + S TP+ T P PP M
Sbjct: 1684 PITTTPSPPTTTMTTPSPTTTPSSPITTTTTPSSTTTPSPPPTTM--------------- 1728
Query: 296 AAEGTASVSPRPPIRQWRTQDHNTPALLPKPSLGRSYSCPDLGPP--GPGTCTWPPAPPQ 353
+ + +P PP T P L + P + PP P + T P P
Sbjct: 1729 -TTPSPTTTPSPPTTTMTT----LPPTTTSSPLTTTPLPPSITPPTFSPFSTTTPTTPCV 1783
Query: 354 P--------SRPRPRRHTVGG 366
P +P H GG
Sbjct: 1784 PLCNWTGWLDSGKPNFHKPGG 1804
Score = 40.4 bits (93), Expect = 0.005
Identities = 47/205 (22%), Positives = 61/205 (29%), Gaps = 66/205 (32%)
Query: 213 PLESPPTAPDPALELPSTPPPSSLLRPRLSPWGLAPLFRSVRSKLESFADIFLTPNKTPQ 272
P++ T P P PS PP S+ P P TP
Sbjct: 1391 PMDKCITTPSPPTTTPSPPPTSTTTLP---------------------------PTTTPS 1423
Query: 273 PP---PPSPPMKLELKIAISEAEQSGAAEGTASVSPRPPIRQWRTQDHNTPALLPKPSLG 329
PP +PP + +P PPI T P P P +
Sbjct: 1424 PPTTTTTTPP---------------------PTTTPSPPITTTTTP---PPTTTPSPPIS 1459
Query: 330 RSYSCPDLGPPGPGTCTWPPAPPQPSRPRPRRHTVGGGEMARAPPP---PRPCLRKEVFP 386
+ + P P P T T P+PP + P T PPP P P + P
Sbjct: 1460 TTTTPPPTTTPSPPTTT--PSPPTTTPSPPTTTTT-------TPPPTTTPSPPTTTPITP 1510
Query: 387 LGGVGASPSLTTSCSSTASTSFSEP 411
P TT T +T+ P
Sbjct: 1511 PASTTTLPPTTTPSPPTTTTTTPPP 1535
Score = 32.7 bits (73), Expect = 0.95
Identities = 51/214 (23%), Positives = 72/214 (33%), Gaps = 47/214 (21%)
Query: 123 TSSTLRRRSRTTPGPEEGPSQKVDRAPQPTLVVMLEDIASPRPPAEGFIDETPNFIIPAQ 182
T++ + + TP P +Q P T + +P P G P A
Sbjct: 4151 TTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTV-----TPTPTPTGTQTGPPTHTSTAP 4205
Query: 183 RAEPMRIVRQPTPPPGDLEPPFQPSALPADPLESPPTAPD---PALELPSTPPPSSLLRP 239
AE + PPP P Q S + PL T PA+E+ ST PPS+ P
Sbjct: 4206 IAE----LTTSNPPPESSTP--QTSRSTSSPLTESTTLLSTLPPAIEMTSTAPPSTPTAP 4259
Query: 240 RLSPWGLAPLFRSVRSKLESFADIFLTPNKTPQPPPPSPPMKLELKIAISEAEQSGAAEG 299
+ G L+P + PP P + G G
Sbjct: 4260 TTTSGGHT-----------------LSPPPSTTTSPPGTPTR-------------GTTTG 4289
Query: 300 TASVSPRPPIRQWRTQDHNTPALLP--KPSLGRS 331
++S +P P Q T TP P PS+ R+
Sbjct: 4290 SSS-APTPSTVQTTTTSAWTPTPTPLSTPSIIRT 4322
>gi|122937251 lysine (K)-specific demethylase 6B [Homo sapiens]
Length = 1682
Score = 60.1 bits (144), Expect = 6e-09
Identities = 109/426 (25%), Positives = 141/426 (33%), Gaps = 67/426 (15%)
Query: 4 PGDSSPPGQPRLCRQP---LTR-ALWGARSPKRPRLQLPGAPSPLEKASRRVLAVVLEDV 59
P PP P L P LT+ LW + G+ P + R L
Sbjct: 257 PPPPPPPPLPGLATSPPFQLTKPGLWSTLHGDAWGPERKGSAPPERQEQRHSLP------ 310
Query: 60 MAVHMVPVVPSKQTSIPQHHSYHQDPVHRQPPASPPRQAGWSSQARPPDPLCLCREPLSR 119
H P T+ P P HR PA+PP A L R P S
Sbjct: 311 ---HPYPYPAPAYTAHP--------PGHRLVPAAPPGPGPRPPGAESHGCLPATRPPGSD 359
Query: 120 IHRTSSTLRRRSRTTPGPEEGPSQKVDRAPQ--PTLVVMLEDIASPRPPAEGFIDETPNF 177
+ R S R R ++ P + V AP P L +S G PN
Sbjct: 360 L-RESRVQRSRMDSSVSPA-ATTACVPYAPSRPPGLPGTTTSSSSSSSSNTGLRGVEPNP 417
Query: 178 IIPAQRAEPMRIVRQPTPPPGDLEPPFQPSALP--ADPLESPPTAPDPALELPSTPPPSS 235
IP A+ + G L P S P P +P + P P PP
Sbjct: 418 GIPG--ADHYQTPALEVSHHGRLGPSAHSSRKPFLGAPAATPHLSLPPGPSSPPPPPCPR 475
Query: 236 LLRPRLSP-WGLAPLFRSVRSKLESFADIFLTPNKTPQPPPPSPPMKLELKIAISEAEQS 294
LLRP P W P R+ R E ++F P+P PP P +
Sbjct: 476 LLRPPPPPAWLKGPACRAAREDGEILEELFFGTEGPPRPAPPPLPHR------------- 522
Query: 295 GAAEGTASVSPRPPIRQWR--TQDHNTPALLPKPSLGRSYSCPDLGPPGP-GTCTWPPAP 351
EG PP ++ TQD +TP P P+ S S P G ++PP P
Sbjct: 523 ---EGFLG----PPASRFSVGTQDSHTPPTPPTPTTSSSNSNSGSHSSSPAGPVSFPP-P 574
Query: 352 PQPSRPRPRRHTVGGGEMARAPPPPRPCLRKEVFPLG--GVGASPSLTTSCSSTASTSFS 409
P +R + P PP P + PL + P+ +SC S SF
Sbjct: 575 PYLAR-----------SIDPLPRPPSPAQNPQDPPLVPLTLALPPAPPSSCHQNTSGSFR 623
Query: 410 EPAEPR 415
P PR
Sbjct: 624 RPESPR 629
Score = 56.2 bits (134), Expect = 8e-08
Identities = 126/520 (24%), Positives = 167/520 (32%), Gaps = 132/520 (25%)
Query: 4 PGDSSPPGQP--RLCRQP--------------------LTRALWGARSPKRPRLQLPGAP 41
PG SSPP P RL R P L +G P RP AP
Sbjct: 463 PGPSSPPPPPCPRLLRPPPPPAWLKGPACRAAREDGEILEELFFGTEGPPRP------AP 516
Query: 42 SPLEK--------ASRRVLAVVLEDVMAVHMVPVVPSKQTSIPQHHSYHQDPVHRQPPAS 93
PL ASR + P S ++ H S PV PP
Sbjct: 517 PPLPHREGFLGPPASRFSVGTQDSHTPPTPPTPTTSSSNSNSGSHSSSPAGPVSFPPPPY 576
Query: 94 PPRQAGWSSQARPPDP-------------LCLCREPLSRIHR-TSSTLRR----RSRTT- 134
R RPP P L L P S H+ TS + RR R R +
Sbjct: 577 LARSI--DPLPRPPSPAQNPQDPPLVPLTLALPPAPPSSCHQNTSGSFRRPESPRPRVSF 634
Query: 135 -------PGPEEGPSQKVDRAPQPTLVVMLEDIAS-------PRPPAEGFIDETPNF-II 179
PGP GP K APQP + E A P P E +E F I+
Sbjct: 635 PKTPEVGPGPPPGPLSK---APQPVPPGVGELPARGPRLFDFPPTPLEDQFEEPAEFKIL 691
Query: 180 PAQRAEPMRIVRQ----------------PTPPPGDLEPPFQPSALPADPLESPPTAPDP 223
P A M+++ + P PP L+ PF P P ++ PT P
Sbjct: 692 PDGLANIMKMLDESIRKEEEQQQHEAGVAPQPP---LKEPFASLQSPF-PTDTAPTTTAP 747
Query: 224 ALELPSTPPPSSLLRPRLSPWGLAPLFRSVRSKLESFADIFLTPNKTPQPPPPSPPMKLE 283
A+ + +T ++ P L F + + P PPPPSP L+
Sbjct: 748 AVAVTTTTTTTTTTTATQEEEKKPPPALPPPPPLAKFPPP--SQPQPPPPPPPSPASLLK 805
Query: 284 LKIAISEAEQSGAAEGTASVSPRPPIRQWRTQDHNTPALLPKPSLGRSYSCPDLGPPGPG 343
++ E ++ A+VS RP P P+ S P P
Sbjct: 806 SLASVLEGQKYCYRGTGAAVSTRPG---------------PLPTTQYSPGPPSGATALPP 850
Query: 344 TCTWPPA--PPQPSRPRPRRHTVGGGEMAR----------------APPPP--RPCLRKE 383
T P A PQPS + + GG AR PPPP P R E
Sbjct: 851 TSAAPSAQGSPQPSASSSSQFSTSGGPWARERRAGEEPVPGPMTPTQPPPPLSLPPARSE 910
Query: 384 VFPLGGVGASPSLTTSCSSTASTSFSEPAEPRLGSTKGKE 423
L + + ++T ++P + + G E
Sbjct: 911 SEVLEEISRACETLVERVGRSATDPADPVDTAEPADSGTE 950
Score = 38.9 bits (89), Expect = 0.013
Identities = 118/552 (21%), Positives = 175/552 (31%), Gaps = 104/552 (18%)
Query: 5 GDSSPPGQPRLCRQPLTRALWGARSPKRPRLQLPGAPSPLEKASRRVLAV-VLEDVMAVH 63
G PPG QP+ + G + PRL P+PLE +L D +A
Sbjct: 641 GPGPPPGPLSKAPQPVPPGV-GELPARGPRL-FDFPPTPLEDQFEEPAEFKILPDGLANI 698
Query: 64 MVPVVPSKQTSIPQHHSYHQDPVHRQPPASPP---RQAGWSSQARPPDPLCLCREPLSRI 120
M + S + Q H+ V QPP P Q+ + + P +
Sbjct: 699 MKMLDESIRKEEEQQQ--HEAGVAPQPPLKEPFASLQSPFPTDTAPTTTAPAVAVTTTTT 756
Query: 121 HRTSSTLRRRSRTTPGPEEGPSQKVDRAPQPTLVVMLEDIASPRPPAEGFIDETPNFIIP 180
T++T + P P P + + P P+ P PP+ + ++ ++
Sbjct: 757 TTTTTTATQEEEKKPPPALPPPPPLAKFPPPSQ----PQPPPPPPPSPASLLKSLASVLE 812
Query: 181 AQ----RAEPMRIVRQPTPPPGDLEPPFQPSALPA-DPLESPPTA--------------- 220
Q R + +P P P P PS A P + P+A
Sbjct: 813 GQKYCYRGTGAAVSTRPGPLPTTQYSPGPPSGATALPPTSAAPSAQGSPQPSASSSSQFS 872
Query: 221 ---------------PDPALELPSTPPPSSLLRP-RLSPWGLAPLFRSVRSKLESFADIF 264
P P P+ PPP L P R L + R+ + +E
Sbjct: 873 TSGGPWARERRAGEEPVPGPMTPTQPPPPLSLPPARSESEVLEEISRACETLVERVGRSA 932
Query: 265 LTPNKTPQPPPPSPPMKLELKIAISEAEQSGAAEGTASVSPRPPIRQWRTQDHN------ 318
P P + P + + A+ A G A+VS RQ Q +
Sbjct: 933 TDP---ADPVDTAEPADSGTERLLPPAQAKEEAGGVAAVSGSCKRRQKEHQKEHRRHRRA 989
Query: 319 ---------------TPALLPKPSL---------------GRSYSCPDLGPPG---PGTC 345
A +PK GR S PDLG P T
Sbjct: 990 CKDSVGRRPREGRAKAKAKVPKEKSRRVLGNLDLQSEEIQGREKSRPDLGGASKAKPPTA 1049
Query: 346 TWPPAPPQPS-RPRPRRHTVGGGEMARAPPPPRPCLRKEVFPLGGVGASPS-------LT 397
PP+ P PS +P P +V G + P P R ++ L + P +
Sbjct: 1050 PAPPSAPAPSAQPTPPSASVPGKKAREEAPGPPGVSRADMLKLRSLSEGPPKELKIRLIK 1109
Query: 398 TSCSSTASTSFSEPAEPRLGSTKGKEPRASKDQVLSEPETKTMGKVSRFRIRRTPA---R 454
+ SE E RL + D V + K GK + +PA +
Sbjct: 1110 VESGDKETFIASEVEERRLRMADLTISHCAADVVRASRNAKVKGKFRESYL--SPAQSVK 1167
Query: 455 PQLNLTPMGLPR 466
P++N T LPR
Sbjct: 1168 PKIN-TEEKLPR 1178
Score = 33.5 bits (75), Expect = 0.56
Identities = 78/315 (24%), Positives = 94/315 (29%), Gaps = 111/315 (35%)
Query: 145 VDRAPQPTLVVMLEDIASPRPPAEGFIDETPNFIIPAQRAEPMRIVRQPTPPPGDLEPPF 204
V RA +P +V P PPA + P + Q PPG P
Sbjct: 197 VKRAAEPPVV-------QPVPPAALSGPSGEEGLSPGGKRRRGCNSEQTGLPPG---LPL 246
Query: 205 QPSALPADPLESPPTAPDPALELPSTPPPSSLLRPRL------SPW-----GLAPLFRSV 253
P LP P PP P P L +T PP L +P L W G AP R
Sbjct: 247 PPPPLPPPP--PPPPPPPPPLPGLATSPPFQLTKPGLWSTLHGDAWGPERKGSAPPERQE 304
Query: 254 RSKLESFADIFLTPNKTPQPP--------PPSPPMK--------------------LELK 285
+ + P T PP PP P + E +
Sbjct: 305 QRHSLPHPYPYPAPAYTAHPPGHRLVPAAPPGPGPRPPGAESHGCLPATRPPGSDLRESR 364
Query: 286 IAISEAEQSGAAEGTASVSP----RPPIRQWRT------------------------QDH 317
+ S + S + T + P RPP T DH
Sbjct: 365 VQRSRMDSSVSPAATTACVPYAPSRPPGLPGTTTSSSSSSSSNTGLRGVEPNPGIPGADH 424
Query: 318 -NTPAL--------------LPKPSLGRSYSCPDLG-PPGPGTCTWPPAPPQPSRPRPRR 361
TPAL KP LG + P L PPGP + PP PP P RP
Sbjct: 425 YQTPALEVSHHGRLGPSAHSSRKPFLGAPAATPHLSLPPGPSS---PPPPPCPRLLRP-- 479
Query: 362 HTVGGGEMARAPPPP 376
PPPP
Sbjct: 480 -----------PPPP 483
>gi|19718731 bromodomain-containing protein 4 isoform long [Homo
sapiens]
Length = 1362
Score = 58.2 bits (139), Expect = 2e-08
Identities = 103/429 (24%), Positives = 153/429 (35%), Gaps = 69/429 (16%)
Query: 66 PVVPSKQTSIPQHHSYHQDPVHRQPPASPPRQAGWSSQARPPDPLCLCREPLSRIHRTSS 125
P P +Q P Q P PP S P+QA + ++ PP P + P+ S
Sbjct: 757 PPPPPQQPPPPPPPQQQQQPPPPPPPPSMPQQAAPAMKSSPP-PFIATQVPVLEPQLPGS 815
Query: 126 TLRRRSRTT------PGPEEGPSQKVDRAPQPTLVVMLEDIASPRPPAEGFIDETPNFII 179
T P PE P + + P+ + L A PPA + +
Sbjct: 816 VFDPIGHFTQPILHLPQPELPP--HLPQPPEHSTPPHLNQHAVVSPPA-------LHNAL 866
Query: 180 PAQRAEPMRIVRQPTPPPGDLEPPFQPSALPADP-LESPPTAPDPALELPSTPPPSSLLR 238
P Q + P R PP PP AL P L PP A P + L PP+
Sbjct: 867 PQQPSRPSN--RAAALPPKPARPPAVSPALTQTPLLPQPPMAQPPQVLLEDEEPPA---- 920
Query: 239 PRLSPWGLAPLFRSVRSKLESFADIFLTPNKTPQPPPPSPP-------MKLELKIAISEA 291
P L+ + L+ K++ + + QPPPP PP +L+ +
Sbjct: 921 PPLTSMQM-QLYLQQLQKVQPPTPLLPSVKVQSQPPPPLPPPPHPSVQQQLQQQPPPPPP 979
Query: 292 EQSGAAEGTASVSPRPPIRQWRTQDHNTPALLPKPSLGRSYSCPDLGPPGPGTCTWPPAP 351
Q P P+ + +T P P G+ P PPG P P
Sbjct: 980 PQPQPPPQQQHQPPPRPV-HLQPMQFSTHIQQPPPPQGQQ---PPHPPPGQ-----QPPP 1030
Query: 352 PQPSRPR--------PRRHTVGGGEMARAPPPPRPCLRKEVFPLGGVGASPSLTTSCSST 403
PQP++P+ PR H ++ P LR+ PL + SP ++ S T
Sbjct: 1031 PQPAKPQQVIQHHHSPRHH--------KSDPYSTGHLREAPSPL--MIHSPQMSQFQSLT 1080
Query: 404 ASTSFSEPAEPRLGSTKGKEPRASKDQVLSEPETKTMGKVSRFR---IRRTPARPQLNLT 460
+ + +P K +E RA+ + +P+ + K + IR P P L
Sbjct: 1081 HQSPPQQNVQP-----KKQELRAAS---VVQPQPLVVVKEEKIHSPIIRSEPFSPSLRPE 1132
Query: 461 PMGLPRPIR 469
P P I+
Sbjct: 1133 PPKHPESIK 1141
Score = 55.5 bits (132), Expect = 1e-07
Identities = 75/315 (23%), Positives = 106/315 (33%), Gaps = 71/315 (22%)
Query: 78 HHSYHQDPVHRQPPASPPRQAGWSSQARPPDPLCLCREPLSRIHRTSSTLRRRSRTTPGP 137
HH +HQ +Q PA P+Q Q PP P ++ + P P
Sbjct: 739 HHHHHQQM--QQAPAPVPQQPPPPPQQPPPPP-----------------PPQQQQQPPPP 779
Query: 138 EEGPSQKVDRAP-----QPTLVVMLEDIASPRPPAEGFIDETPNFIIPAQRAEPMRIVRQ 192
PS AP P + + P+ P F D +F +P+ + Q
Sbjct: 780 PPPPSMPQQAAPAMKSSPPPFIATQVPVLEPQLPGSVF-DPIGHF------TQPILHLPQ 832
Query: 193 PTPPPGDLEPP--FQPSALPADPLESPPTAPDPALELPSTP-------PPSSLLRPRLSP 243
P PP +PP P L + SPP + + PS P PP P +SP
Sbjct: 833 PELPPHLPQPPEHSTPPHLNQHAVVSPPALHNALPQQPSRPSNRAAALPPKPARPPAVSP 892
Query: 244 WGLAPLFRSVRSKLESFADIFLTPNKTPQPPPPSPPMKLELKIAISEAEQSGAAEGTASV 303
L + + + L + P PP S M+L L+ + + +
Sbjct: 893 -ALTQTPLLPQPPMAQPPQVLLEDEEPPAPPLTSMQMQLYLQ-QLQKVQ----------- 939
Query: 304 SPRPPIRQWRTQDHNTPALLPKPSLGRSYSCPDLGPPGPGTCTWPPAPPQPSRPRPRRHT 363
P P + + Q P L P P P PP PPQP P ++H
Sbjct: 940 PPTPLLPSVKVQSQPPPPLPPPPHPSVQQQLQQQPP--------PPPPPQPQPPPQQQH- 990
Query: 364 VGGGEMARAPPPPRP 378
PPPRP
Sbjct: 991 ---------QPPPRP 996
Score = 50.4 bits (119), Expect = 4e-06
Identities = 114/495 (23%), Positives = 162/495 (32%), Gaps = 113/495 (22%)
Query: 4 PGDSSPPGQPRLCRQPLTRALWGARSPKRPRLQLPGAPSPLEKASRRVLAV----VLE-- 57
P PP P+ +QP P P +P +P K+S VLE
Sbjct: 761 PQQPPPPPPPQQQQQP---------PPPPPPPSMPQQAAPAMKSSPPPFIATQVPVLEPQ 811
Query: 58 ------DVMAVHMVPVVPSKQTSIPQHHSYHQDPVHRQPP-------ASPPRQAGWSSQA 104
D + P++ Q +P H Q P H PP SPP A
Sbjct: 812 LPGSVFDPIGHFTQPILHLPQPELPPH--LPQPPEHSTPPHLNQHAVVSPPAL----HNA 865
Query: 105 RPPDPLCLCREPLSRIHRTSSTLRRRSRTTPGPEEGPSQKVDRAPQPTLV----VMLEDI 160
P P SR ++ L + P +Q PQP + V+LED
Sbjct: 866 LPQQP--------SRPSNRAAALPPKPARPPAVSPALTQ-TPLLPQPPMAQPPQVLLEDE 916
Query: 161 ASPRPPAEGFIDETPNFIIPAQRAEP----MRIVRQPTPPPGDLEPPFQPSA---LPADP 213
P PP + ++ Q+ +P + V+ + PP L PP PS L P
Sbjct: 917 EPPAPPLTSM--QMQLYLQQLQKVQPPTPLLPSVKVQSQPPPPLPPPPHPSVQQQLQQQP 974
Query: 214 LESPPTAPDPALELPSTPPPSSLLRPRLSPWGLAPLFRSVRSKLESFADIFLTPNKTP-Q 272
PP P P + PPP P L P+ S + P+ P Q
Sbjct: 975 PPPPPPQPQPPPQQQHQPPP--------RPVHLQPMQFSTHIQQPPPPQGQQPPHPPPGQ 1026
Query: 273 PPPPSPPMKLELKIAISEAEQSGAAEGTASVSPRPPIRQWRTQDHNTPALLPKPSLGRSY 332
PPP P K + I + + ++ P ++ +P ++ P + +
Sbjct: 1027 QPPPPQPAKPQQVIQHHHSPRHHKSD---------PYSTGHLREAPSPLMIHSPQMSQFQ 1077
Query: 333 SCPDLGPPGPGTCTWPPAPPQPSRPRPRRHTVGGGEMARAPPPPRPCLRKEVFPLGGVGA 392
S PP QP + R +V P P +++E
Sbjct: 1078 SLTHQSPPQQNV--------QPKKQELRAASV-------VQPQPLVVVKEEKI------H 1116
Query: 393 SPSLTTSCSSTASTSFSEPAEPRLGSTKGKEPRASKDQV--LSEPETKTMGKVSRFRIRR 450
SP + SEP P L K P + K V PE K + V R IR
Sbjct: 1117 SPIIR-----------SEPFSPSLRPEPPKHPESIKAPVHLPQRPEMKPV-DVGRPVIR- 1163
Query: 451 TPARPQLNLTPMGLP 465
P+ N P G P
Sbjct: 1164 ---PPEQNAPPPGAP 1175
Score = 32.7 bits (73), Expect = 0.95
Identities = 30/128 (23%), Positives = 43/128 (33%), Gaps = 20/128 (15%)
Query: 166 PAEGFIDETPNFIIPAQRAEPMRIVRQPTPPPGDLEP-PFQP------------SALPAD 212
P + T P Q P QP PPP P PF + +P
Sbjct: 191 PGVSTVPNTTQASTPPQTQTP-----QPNPPPVQATPHPFPAVTPDLIVQTPVMTVVPPQ 245
Query: 213 PLESPPTAPDPALELPSTPPPSSLLRPRLSPWGLAPL--FRSVRSKLESFADIFLTPNKT 270
PL++PP P P+ P P + P+ + V+ K ++ + P
Sbjct: 246 PLQTPPPVPPQPQPPPAPAPQPVQSHPPIIAATPQPVKTKKGVKRKADTTTPTTIDPIHE 305
Query: 271 PQPPPPSP 278
P PP P
Sbjct: 306 PPSLPPEP 313
>gi|163914392 glioma tumor suppressor candidate region gene 1 [Homo
sapiens]
Length = 1560
Score = 57.0 bits (136), Expect = 5e-08
Identities = 106/419 (25%), Positives = 145/419 (34%), Gaps = 82/419 (19%)
Query: 11 GQPRLCRQPLTRALWGARSPKRPRLQLPGAPSPLEKASRRVLAVVLEDVMAVHMVPVVPS 70
GQP L + P++ A + +P P A + L+ + AV + + + P P+
Sbjct: 550 GQPALFQMPVSLAAGSLPTQSQPAPAGPAATTVLQGVTLPPSAVAMLNTPDGLVQPATPA 609
Query: 71 KQTS----------IPQHHSYH--------QDPVHRQPPASPPRQAGWSSQARPPDP--- 109
T PQ Q P +QPP +P QA QA P P
Sbjct: 610 AATGEAAPVLTVQPAPQAPPAVSTPLPLGLQQPQAQQPPQAPTPQAAAPPQATTPQPSPG 669
Query: 110 LCLCREPLSRIHRTSST----LRRRSRTTPGPEEGPSQKVDRAPQPTLVVMLEDIASPRP 165
L E + S+T L + S P+E Q + A P L V I S P
Sbjct: 670 LASSPEKIVLGQPPSATPTAILTQDSLQMFLPQERSQQPLS-AEGPHLSVPASVIVSAPP 728
Query: 166 PAEGFIDETPNFIIPAQRAEPMRIVRQPTPPPGDLEP---PFQ---PSALPADPLESP-- 217
PA+ TP + P Q +P P P P + PS+ P+ P ++P
Sbjct: 729 PAQDPAPATP--VAKGAGLGPQAPDSQASPAPAPQIPAAAPLKGPGPSSSPSLPHQAPLG 786
Query: 218 --PTAPDP-ALELPSTPP--PSSLLRPRLSPWGLAPLFRSVRSKLESFADIFLTPNKTPQ 272
P P P PS PP P S+ RP P PL P
Sbjct: 787 DSPHLPSPHPTRPPSRPPSRPQSVSRPPSEP----PLH--------------------PC 822
Query: 273 PPPPSPPMKLELKIAISEAEQSGAAEGTASVSPRPPIRQWRTQD-----------HNTPA 321
PPP +PP + + ++ A A +P PP R Q H P+
Sbjct: 823 PPPQAPPTLPGIFVIQNQLGVPPPASNPAPTAPGPPQPPLRPQSQPPEGPLPPAPHLPPS 882
Query: 322 LLPKPSLGRSYSCPDLGPPGPG--TCTWPPA--PPQPSRPRPRRHTVGGGEMARAPPPP 376
S + L P P +PP+ P + P P H V E A PPPP
Sbjct: 883 STSSAVASSSETSSRLPAPTPSDFQLQFPPSQGPHKSPTPPPTLHLV--PEPAAPPPPP 939
Score = 51.2 bits (121), Expect = 3e-06
Identities = 77/309 (24%), Positives = 106/309 (34%), Gaps = 45/309 (14%)
Query: 136 GPEEGPSQKVDRAPQPTLVVMLE-----DIASPRPPAEGFIDETPNFIIPAQRAEPMRIV 190
GP+ P + AP P + +SP P + + ++P+ P P R
Sbjct: 746 GPQ-APDSQASPAPAPQIPAAAPLKGPGPSSSPSLPHQAPLGDSPHLPSPHPTRPPSR-- 802
Query: 191 RQPTPPPGDLEPPFQPSALPADPLESPPTAPDPAL--ELPSTPPPSSLLRPRLSPWGLAP 248
P+ P PP +P P P ++PPT P + PPP+S P +P P
Sbjct: 803 -PPSRPQSVSRPPSEPPLHPCPPPQAPPTLPGIFVIQNQLGVPPPASNPAP-TAPGPPQP 860
Query: 249 LFRSVRSKLESFADIFLTPNKTPQPPPPSPPMKLELKIAISEAEQSGAAEGTASVSPRPP 308
R P + P PP P P S +E T+S P P
Sbjct: 861 PLRPQSQ-----------PPEGPLPPAPHLPPSSTSSAVASSSE-------TSSRLPAPT 902
Query: 309 IRQWRTQ------DHNTPALLPKPSLGRSYSCPDLGPPGPGT---CTWP-PAPPQPSRPR 358
++ Q H +P P L + P PP P T T P PA PQP
Sbjct: 903 PSDFQLQFPPSQGPHKSPTPPPTLHLVPEPAAPP--PPPPRTFQMVTTPFPALPQPKALL 960
Query: 359 PRRHTVGGG---EMARAPPPPRPCLRKEVFPLGGVGASPSLTTSCSSTASTSFSEPAEPR 415
R H V G + P P + PL AS ++ S T+ S P
Sbjct: 961 ERFHQVPSGIILQNKAGGAPAAPQTSTSLGPLTSPAASVLVSGQAPSGTPTAPSHAPAPA 1020
Query: 416 LGSTKGKEP 424
+ G P
Sbjct: 1021 PMAATGLPP 1029
Score = 50.1 bits (118), Expect = 6e-06
Identities = 76/298 (25%), Positives = 111/298 (37%), Gaps = 33/298 (11%)
Query: 151 PTLVVML---EDIASPRPPAEGFIDETPNFII-PAQRAEPMRIVRQPTPPPGDLEPPF-- 204
P+ V ML + + P PA + P + PA +A P TP P L+ P
Sbjct: 590 PSAVAMLNTPDGLVQPATPAAATGEAAPVLTVQPAPQAPPA----VSTPLPLGLQQPQAQ 645
Query: 205 QPSALPADPLESPP--TAPDPALELPSTP-------PPSSLLRPRLSPWGLAPLFRSVRS 255
QP P +PP T P P+ L S+P PPS+ L+ L RS
Sbjct: 646 QPPQAPTPQAAAPPQATTPQPSPGLASSPEKIVLGQPPSATPTAILTQDSLQMFLPQERS 705
Query: 256 KLESFAD---IFLTPNKTPQPPPPSPPMKLELKIAISEAEQSGAAEGTASVSPRPPIRQW 312
+ A+ + + + PPP+ +A A + AS +P P I
Sbjct: 706 QQPLSAEGPHLSVPASVIVSAPPPAQDPAPATPVAKGAGLGPQAPDSQASPAPAPQIPAA 765
Query: 313 RTQD----HNTPALLPKPSLGRSYSCPDLGPPGPGTCTWPPAPPQPSRPRPRRHTVGGGE 368
++P+L + LG S P L P P T PP+ P PSRP+
Sbjct: 766 APLKGPGPSSSPSLPHQAPLGDS---PHLPSPHP---TRPPSRP-PSRPQSVSRPPSEPP 818
Query: 369 MARAPPPPRPCLRKEVFPLGGVGASPSLTTSCSSTASTSFSEPAEPRLGSTKGKEPRA 426
+ PPP P +F + P ++ + TA P P+ +G P A
Sbjct: 819 LHPCPPPQAPPTLPGIFVIQNQLGVPPPASNPAPTAPGPPQPPLRPQSQPPEGPLPPA 876
Score = 33.9 bits (76), Expect = 0.43
Identities = 22/62 (35%), Positives = 28/62 (45%), Gaps = 14/62 (22%)
Query: 190 VRQPTPPPGDLEPPFQPSALPADPLESPPTAPDPALELPST---PPPSSLLRPRLSPWGL 246
V QP PPP L+ A+P PP P P ++ T PPP++ P P G
Sbjct: 1330 VHQPPPPPATLKV--------AEPPPRPPPPPPPTGQMNGTVDHPPPAA---PERKPLGT 1378
Query: 247 AP 248
AP
Sbjct: 1379 AP 1380
Score = 30.4 bits (67), Expect = 4.7
Identities = 46/201 (22%), Positives = 67/201 (33%), Gaps = 40/201 (19%)
Query: 274 PPPSPPMKLELK------------------IAISEAEQSGAA------EGTASVSPRPPI 309
PPP P KL ++ ++ S + S A+ +G RPPI
Sbjct: 1238 PPPHLPTKLVIRHGGAGGSPSVTWARASSSLSSSSSSSSAASSLDADEDGPMPSRNRPPI 1297
Query: 310 RQWRTQDHNTPALLPKPSLGRSYSCPDLG-------PPGPGTCTWPPAPPQPSRPRPRRH 362
+ + + L K G S + PP P T PP+P P P
Sbjct: 1298 KTYEARSRIGLKLKIKQEAGLSKVVHNTALDPVHQPPPPPATLKVAEPPPRPPPPPPPTG 1357
Query: 363 TVGGGEMARAPPPPRPCLRKEVFPLGGVGASPSLTTSCSSTASTSFSEPAEPRLGSTKGK 422
+ G PPP P E PLG P L T + P P G+ G+
Sbjct: 1358 QMNG--TVDHPPPAAP----ERKPLGTAPHCPRL--PLRKTYRENVGGPGAPE-GTPAGR 1408
Query: 423 EPRASKDQVLSEPETKTMGKV 443
S + ++ + T G +
Sbjct: 1409 ARGGSPAPLPAKVDEATSGLI 1429
Score = 29.6 bits (65), Expect = 8.0
Identities = 49/219 (22%), Positives = 69/219 (31%), Gaps = 38/219 (17%)
Query: 79 HSYHQDPVHRQ---------------PPASPPRQAGWSSQARPPDPLCLCREPLSRI-HR 122
H+ DPVH+ PP PP + P P R+PL H
Sbjct: 1323 HNTALDPVHQPPPPPATLKVAEPPPRPPPPPPPTGQMNGTVDHPPPAAPERKPLGTAPHC 1382
Query: 123 TSSTLRRRSRTT---PGPEEGPSQKVDRAPQPTLVVMLEDIASPRPPAEGFIDETPNFII 179
LR+ R PG EG R P P +DE + +I
Sbjct: 1383 PRLPLRKTYRENVGGPGAPEGTPAGRARGGSPA-------------PLPAKVDEATSGLI 1429
Query: 180 PAQRAEPMRIVRQ--PTPPPGDLEPPFQPSALPADPLESPPTAPDPALELPSTPPPSSLL 237
A + ++ PPP EP + DP P P +P
Sbjct: 1430 RELAAVEDELYQRMLKGPPP---EPAASAAQGTGDPDWEAPGLPPAKRRKSESPDVDQAS 1486
Query: 238 RPRLSPWGLAPLFRSVRSKLESFADIFLTPNKTPQPPPP 276
SP L ++S ++S ++ P +TP P P
Sbjct: 1487 FSSDSPQD-DTLTEHLQSAIDSILNLQQAPGRTPAPSYP 1524
>gi|68161504 Wiskott-Aldrich syndrome protein family member 1 [Homo
sapiens]
Length = 559
Score = 56.2 bits (134), Expect = 8e-08
Identities = 70/240 (29%), Positives = 86/240 (35%), Gaps = 45/240 (18%)
Query: 135 PGPEEGPSQKVDRAPQPTLVVMLEDIASPRP--PAEGFIDETPNFIIPAQRAEPMRIVRQ 192
P P G D P PT + + RP PA G TP F+ P
Sbjct: 281 PPPMHGAG---DAKPIPTCISSATGLIENRPQSPATG---RTPVFVSPT----------- 323
Query: 193 PTPPPGDLEPPFQPSALPADPLESPPTAPDPALELPSTPPPSSLLRPRLSPWGLAPLFRS 252
P PPP PP PSAL L + T+ P P PPP++ L+ P APL
Sbjct: 324 PPPPP----PPL-PSALSTSSLRASMTSTPPPPVPPPPPPPATALQAPAVPPPPAPL--- 375
Query: 253 VRSKLESFADIFLTPNKTPQPPP---PSPPMKLELKIAIS---EAEQSGAAEGTASVSPR 306
A L P P PP PSPP+ + + G +G P
Sbjct: 376 ------QIAPGVLHPAPPPIAPPLVQPSPPVARAAPVCETVPVHPLPQGEVQGLPPPPPP 429
Query: 307 PPIRQ--WRTQDHNTPALLPKPSLGRSYSCPDLGPPGPGTCTWPPAPPQPSRP--RPRRH 362
PP+ R T L P G + P PGP PP+PP P P+RH
Sbjct: 430 PPLPPPGIRPSSPVTVTALAHPPSG-LHPTPSTA-PGPHVPLMPPSPPSQVIPASEPKRH 487
Score = 48.5 bits (114), Expect = 2e-05
Identities = 65/233 (27%), Positives = 81/233 (34%), Gaps = 60/233 (25%)
Query: 183 RAEPMRIVRQPTPPPGDLEPPFQPSALPADPLESPPTAPDPALELPSTPPPSSLLRPRLS 242
RAE +VR PPP PP A A P+ PT A L RP+
Sbjct: 266 RAEERVLVRPHEPPP----PPPMHGAGDAKPI---PTCISSATGLIEN-------RPQSP 311
Query: 243 PWGLAPLFRSVRSKLESFADIFLTPNKTPQPPPPSPPMKLELKIAISEAEQSGAAEGTAS 302
G P+F S P PPPP PP+ L + A +
Sbjct: 312 ATGRTPVFVS------------------PTPPPPPPPLPSALSTSSLRASMTSTPPPPVP 353
Query: 303 VSPRPPIRQWRTQDHNTPALLPKPSLGRSYSCPDLGPPGPGTCTWPPAPP--QPSRPRPR 360
P PP + PA+ P P+ P + P P P APP QPS P R
Sbjct: 354 PPPPPPATALQA-----PAVPPPPA--PLQIAPGVLHPAPP----PIAPPLVQPSPPVAR 402
Query: 361 R---------HTVGGGEMARAPPPPRPCLRKEVFPLGGVGASPSLTTSCSSTA 404
H + GE+ PPPP P PL G PS + ++ A
Sbjct: 403 AAPVCETVPVHPLPQGEVQGLPPPPPPP------PLPPPGIRPSSPVTVTALA 449
Score = 41.2 bits (95), Expect = 0.003
Identities = 58/218 (26%), Positives = 82/218 (37%), Gaps = 43/218 (19%)
Query: 199 DLEPPFQPSALPADP----------LESPPTAPDPA------LELPSTPPPSSLLRPRL- 241
+L+ P +P +P P + P A D A +E+ + P RP+
Sbjct: 183 NLDRPHEPEKVPRAPHDRRREWQKLAQGPELAEDDANLLHKHIEVANGPASHFETRPQTY 242
Query: 242 -----SPWGLAPLFRSVRSKLESFAD--IFLTPNKTPQPPP--------PSPPMKLELKI 286
+ L+ L S S+L + A+ + + P++ P PPP P P
Sbjct: 243 VDHMDGSYSLSALPFSQMSELLTRAEERVLVRPHEPPPPPPMHGAGDAKPIPTCISSATG 302
Query: 287 AISEAEQSGAAEGT-ASVSPRPPIRQWRTQDHNTPALLPKPSLGRSYSC---PDLGPPGP 342
I QS A T VSP PP P+ L SL S + P + PP P
Sbjct: 303 LIENRPQSPATGRTPVFVSPTPP-----PPPPPLPSALSTSSLRASMTSTPPPPVPPPPP 357
Query: 343 GTCTWPPAPPQPSRPRPRRHTVGGGEMARAPPPPRPCL 380
T AP P P P + + G + APPP P L
Sbjct: 358 PPATALQAPAVPPPPAPLQ--IAPGVLHPAPPPIAPPL 393
Score = 35.8 bits (81), Expect = 0.11
Identities = 51/208 (24%), Positives = 72/208 (34%), Gaps = 51/208 (24%)
Query: 66 PVVPSKQTSIPQHHSYHQDPVHRQPPASPPRQAGWSSQARPPDPLCLCREPLSRIHRTSS 125
P +PS ++ S P PP PP + A PP P L
Sbjct: 329 PPLPSALSTSSLRASMTSTPPPPVPPPPPPPATALQAPAVPPPPAPL------------- 375
Query: 126 TLRRRSRTTPGPEEGPSQKVDRAPQPTLVVMLEDIASPRPP---AEGFIDETPNFIIPAQ 182
+ PG + AP P + + P PP A + P +P
Sbjct: 376 ------QIAPG-------VLHPAPPP----IAPPLVQPSPPVARAAPVCETVPVHPLPQG 418
Query: 183 RAEPMRIVRQPTPPPGDLEPP-FQPSA---------LPADPLESPPTAPDPALELPSTPP 232
+ + P PPP L PP +PS+ P+ +P TAP P + L P
Sbjct: 419 EVQGL----PPPPPPPPLPPPGIRPSSPVTVTALAHPPSGLHPTPSTAPGPHVPLMPPSP 474
Query: 233 PSSLL---RPRLSPWGLAPLFRSVRSKL 257
PS ++ P+ P L P+ RS L
Sbjct: 475 PSQVIPASEPKRHPSTL-PVISDARSVL 501
>gi|68161502 Wiskott-Aldrich syndrome protein family member 1 [Homo
sapiens]
Length = 559
Score = 56.2 bits (134), Expect = 8e-08
Identities = 70/240 (29%), Positives = 86/240 (35%), Gaps = 45/240 (18%)
Query: 135 PGPEEGPSQKVDRAPQPTLVVMLEDIASPRP--PAEGFIDETPNFIIPAQRAEPMRIVRQ 192
P P G D P PT + + RP PA G TP F+ P
Sbjct: 281 PPPMHGAG---DAKPIPTCISSATGLIENRPQSPATG---RTPVFVSPT----------- 323
Query: 193 PTPPPGDLEPPFQPSALPADPLESPPTAPDPALELPSTPPPSSLLRPRLSPWGLAPLFRS 252
P PPP PP PSAL L + T+ P P PPP++ L+ P APL
Sbjct: 324 PPPPP----PPL-PSALSTSSLRASMTSTPPPPVPPPPPPPATALQAPAVPPPPAPL--- 375
Query: 253 VRSKLESFADIFLTPNKTPQPPP---PSPPMKLELKIAIS---EAEQSGAAEGTASVSPR 306
A L P P PP PSPP+ + + G +G P
Sbjct: 376 ------QIAPGVLHPAPPPIAPPLVQPSPPVARAAPVCETVPVHPLPQGEVQGLPPPPPP 429
Query: 307 PPIRQ--WRTQDHNTPALLPKPSLGRSYSCPDLGPPGPGTCTWPPAPPQPSRP--RPRRH 362
PP+ R T L P G + P PGP PP+PP P P+RH
Sbjct: 430 PPLPPPGIRPSSPVTVTALAHPPSG-LHPTPSTA-PGPHVPLMPPSPPSQVIPASEPKRH 487
Score = 48.5 bits (114), Expect = 2e-05
Identities = 65/233 (27%), Positives = 81/233 (34%), Gaps = 60/233 (25%)
Query: 183 RAEPMRIVRQPTPPPGDLEPPFQPSALPADPLESPPTAPDPALELPSTPPPSSLLRPRLS 242
RAE +VR PPP PP A A P+ PT A L RP+
Sbjct: 266 RAEERVLVRPHEPPP----PPPMHGAGDAKPI---PTCISSATGLIEN-------RPQSP 311
Query: 243 PWGLAPLFRSVRSKLESFADIFLTPNKTPQPPPPSPPMKLELKIAISEAEQSGAAEGTAS 302
G P+F S P PPPP PP+ L + A +
Sbjct: 312 ATGRTPVFVS------------------PTPPPPPPPLPSALSTSSLRASMTSTPPPPVP 353
Query: 303 VSPRPPIRQWRTQDHNTPALLPKPSLGRSYSCPDLGPPGPGTCTWPPAPP--QPSRPRPR 360
P PP + PA+ P P+ P + P P P APP QPS P R
Sbjct: 354 PPPPPPATALQA-----PAVPPPPA--PLQIAPGVLHPAPP----PIAPPLVQPSPPVAR 402
Query: 361 R---------HTVGGGEMARAPPPPRPCLRKEVFPLGGVGASPSLTTSCSSTA 404
H + GE+ PPPP P PL G PS + ++ A
Sbjct: 403 AAPVCETVPVHPLPQGEVQGLPPPPPPP------PLPPPGIRPSSPVTVTALA 449
Score = 41.2 bits (95), Expect = 0.003
Identities = 58/218 (26%), Positives = 82/218 (37%), Gaps = 43/218 (19%)
Query: 199 DLEPPFQPSALPADP----------LESPPTAPDPA------LELPSTPPPSSLLRPRL- 241
+L+ P +P +P P + P A D A +E+ + P RP+
Sbjct: 183 NLDRPHEPEKVPRAPHDRRREWQKLAQGPELAEDDANLLHKHIEVANGPASHFETRPQTY 242
Query: 242 -----SPWGLAPLFRSVRSKLESFAD--IFLTPNKTPQPPP--------PSPPMKLELKI 286
+ L+ L S S+L + A+ + + P++ P PPP P P
Sbjct: 243 VDHMDGSYSLSALPFSQMSELLTRAEERVLVRPHEPPPPPPMHGAGDAKPIPTCISSATG 302
Query: 287 AISEAEQSGAAEGT-ASVSPRPPIRQWRTQDHNTPALLPKPSLGRSYSC---PDLGPPGP 342
I QS A T VSP PP P+ L SL S + P + PP P
Sbjct: 303 LIENRPQSPATGRTPVFVSPTPP-----PPPPPLPSALSTSSLRASMTSTPPPPVPPPPP 357
Query: 343 GTCTWPPAPPQPSRPRPRRHTVGGGEMARAPPPPRPCL 380
T AP P P P + + G + APPP P L
Sbjct: 358 PPATALQAPAVPPPPAPLQ--IAPGVLHPAPPPIAPPL 393
Score = 35.8 bits (81), Expect = 0.11
Identities = 51/208 (24%), Positives = 72/208 (34%), Gaps = 51/208 (24%)
Query: 66 PVVPSKQTSIPQHHSYHQDPVHRQPPASPPRQAGWSSQARPPDPLCLCREPLSRIHRTSS 125
P +PS ++ S P PP PP + A PP P L
Sbjct: 329 PPLPSALSTSSLRASMTSTPPPPVPPPPPPPATALQAPAVPPPPAPL------------- 375
Query: 126 TLRRRSRTTPGPEEGPSQKVDRAPQPTLVVMLEDIASPRPP---AEGFIDETPNFIIPAQ 182
+ PG + AP P + + P PP A + P +P
Sbjct: 376 ------QIAPG-------VLHPAPPP----IAPPLVQPSPPVARAAPVCETVPVHPLPQG 418
Query: 183 RAEPMRIVRQPTPPPGDLEPP-FQPSA---------LPADPLESPPTAPDPALELPSTPP 232
+ + P PPP L PP +PS+ P+ +P TAP P + L P
Sbjct: 419 EVQGL----PPPPPPPPLPPPGIRPSSPVTVTALAHPPSGLHPTPSTAPGPHVPLMPPSP 474
Query: 233 PSSLL---RPRLSPWGLAPLFRSVRSKL 257
PS ++ P+ P L P+ RS L
Sbjct: 475 PSQVIPASEPKRHPSTL-PVISDARSVL 501
Database: hs.faa
Posted date: Aug 4, 2009 4:42 PM
Number of letters in database: 18,247,518
Number of sequences in database: 37,866
Lambda K H
0.314 0.133 0.411
Gapped
Lambda K H
0.267 0.0410 0.140
Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Hits to DB: 34,500,941
Number of Sequences: 37866
Number of extensions: 2504402
Number of successful extensions: 25415
Number of sequences better than 10.0: 30
Number of HSP's better than 10.0 without gapping: 240
Number of HSP's successfully gapped in prelim test: 1407
Number of HSP's that attempted gapping in prelim test: 13584
Number of HSP's gapped (non-prelim): 7722
length of query: 585
length of database: 18,247,518
effective HSP length: 108
effective length of query: 477
effective length of database: 14,157,990
effective search space: 6753361230
effective search space used: 6753361230
T: 11
A: 40
X1: 16 ( 7.2 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 42 (21.9 bits)
S2: 65 (29.6 bits)
Search results were obtained with NCBI BLAST and RefSeq entries.
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Guide to the Human Genome
Copyright © 2010 by Stewart Scherer. All rights reserved.