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Search of human proteins with 108936953
BLASTP 2.2.11 [Jun-05-2005]
Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer,
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997),
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs", Nucleic Acids Res. 25:3389-3402.
Query= gi|108936953 protein phosphatase 4, regulatory subunit 1
isoform a [Homo sapiens]
(950 letters)
Database: hs.faa
37,866 sequences; 18,247,518 total letters
Searching..................................................done
Score E
Sequences producing significant alignments: (bits) Value
gi|108936953 protein phosphatase 4, regulatory subunit 1 isoform... 1887 0.0
gi|4826934 protein phosphatase 4, regulatory subunit 1 isoform b... 1842 0.0
gi|21361399 alpha isoform of regulatory subunit A, protein phosp... 73 1e-12
gi|32455246 beta isoform of regulatory subunit A, protein phosph... 65 3e-10
gi|32455244 beta isoform of regulatory subunit A, protein phosph... 65 3e-10
gi|17402886 HEAT-like repeat-containing protein isoform 1 [Homo ... 47 6e-05
gi|24308089 chromodomain helicase DNA binding protein 5 [Homo sa... 41 0.006
gi|115430243 SCY1-like 1 isoform B [Homo sapiens] 39 0.030
gi|115430241 SCY1-like 1 isoform A [Homo sapiens] 39 0.030
gi|154813197 talpid3 protein [Homo sapiens] 37 0.087
gi|56549645 nucleoporin 98kD isoform 4 [Homo sapiens] 36 0.15
gi|21264365 nucleoporin 98kD isoform 1 [Homo sapiens] 36 0.15
gi|7661532 nin one binding protein [Homo sapiens] 36 0.15
gi|22748757 truncated type I keratin KA21 [Homo sapiens] 36 0.19
gi|148747864 JAW1-related protein isoform a [Homo sapiens] 35 0.25
gi|154091334 JAW1-related protein isoform c [Homo sapiens] 35 0.25
gi|154091332 JAW1-related protein isoform b [Homo sapiens] 35 0.25
gi|148728182 JAW1-related protein isoform b [Homo sapiens] 35 0.25
gi|117414137 retinitis pigmentosa 1-like 1 [Homo sapiens] 35 0.33
gi|21361639 DIPB protein [Homo sapiens] 35 0.43
gi|55770895 ERBB2 interacting protein isoform 7 [Homo sapiens] 35 0.43
gi|8923909 ERBB2 interacting protein isoform 2 [Homo sapiens] 35 0.43
gi|188497648 ubiquitin specific peptidase 37 [Homo sapiens] 35 0.43
gi|34577059 adipose differentiation-related protein [Homo sapiens] 34 0.57
gi|23943912 phosphoinositide-3-kinase, regulatory subunit 4 [Hom... 34 0.57
gi|5174573 myeloid/lymphoid or mixed-lineage leukemia trithorax ... 34 0.57
gi|55770902 opioid growth factor receptor-like 1 [Homo sapiens] 34 0.57
gi|34577118 dopey family member 1 [Homo sapiens] 34 0.57
gi|5031703 Ras-GTPase-activating protein SH3-domain-binding prot... 34 0.57
gi|38327552 Ras-GTPase-activating protein SH3-domain-binding pro... 34 0.57
>gi|108936953 protein phosphatase 4, regulatory subunit 1 isoform a
[Homo sapiens]
Length = 950
Score = 1887 bits (4888), Expect = 0.0
Identities = 950/950 (100%), Positives = 950/950 (100%)
Query: 1 MADLSLLQEDLQEDADGFGVDDYSSESDVIIIPSALDFVSQDEMLTPLGRLDKYAASENI 60
MADLSLLQEDLQEDADGFGVDDYSSESDVIIIPSALDFVSQDEMLTPLGRLDKYAASENI
Sbjct: 1 MADLSLLQEDLQEDADGFGVDDYSSESDVIIIPSALDFVSQDEMLTPLGRLDKYAASENI 60
Query: 61 FNRQMVARSLLDTLREVCDDERDCIAVLERISRLADDSEPTVRAELMEQVPHIALFCQEN 120
FNRQMVARSLLDTLREVCDDERDCIAVLERISRLADDSEPTVRAELMEQVPHIALFCQEN
Sbjct: 61 FNRQMVARSLLDTLREVCDDERDCIAVLERISRLADDSEPTVRAELMEQVPHIALFCQEN 120
Query: 121 RPSIPYAFSKFLLPIVVRYLADQNNQVRKTSQAALLALLEQELIERFDVETKVCPVLIEL 180
RPSIPYAFSKFLLPIVVRYLADQNNQVRKTSQAALLALLEQELIERFDVETKVCPVLIEL
Sbjct: 121 RPSIPYAFSKFLLPIVVRYLADQNNQVRKTSQAALLALLEQELIERFDVETKVCPVLIEL 180
Query: 181 TAPDSNDDVKTEAVAIMCKMAPMVGKDITERLILPRFCEMCCDCRMFHVRKVCAANFGDI 240
TAPDSNDDVKTEAVAIMCKMAPMVGKDITERLILPRFCEMCCDCRMFHVRKVCAANFGDI
Sbjct: 181 TAPDSNDDVKTEAVAIMCKMAPMVGKDITERLILPRFCEMCCDCRMFHVRKVCAANFGDI 240
Query: 241 CSVVGQQATEEMLLPRFFQLCSDNVWGVRKACAECFMAVSCATCQEIRRTKLSALFINLI 300
CSVVGQQATEEMLLPRFFQLCSDNVWGVRKACAECFMAVSCATCQEIRRTKLSALFINLI
Sbjct: 241 CSVVGQQATEEMLLPRFFQLCSDNVWGVRKACAECFMAVSCATCQEIRRTKLSALFINLI 300
Query: 301 SDPSRWVRQAAFQSLGPFISTFANPSSSGQYFKEESKSSEEMSVENKNRTRDQEAPEDVQ 360
SDPSRWVRQAAFQSLGPFISTFANPSSSGQYFKEESKSSEEMSVENKNRTRDQEAPEDVQ
Sbjct: 301 SDPSRWVRQAAFQSLGPFISTFANPSSSGQYFKEESKSSEEMSVENKNRTRDQEAPEDVQ 360
Query: 361 VRPEDTPSDLSVSNSSVILENTMEDHAAEASGKPLGEISVPLDSSLLCTLSSESHQEAAS 420
VRPEDTPSDLSVSNSSVILENTMEDHAAEASGKPLGEISVPLDSSLLCTLSSESHQEAAS
Sbjct: 361 VRPEDTPSDLSVSNSSVILENTMEDHAAEASGKPLGEISVPLDSSLLCTLSSESHQEAAS 420
Query: 421 NENDKKPGNYKSMLRPEVGTTSQDSALLDQELYNSFHFWRTPLPEIDLDIELEQNSGGKP 480
NENDKKPGNYKSMLRPEVGTTSQDSALLDQELYNSFHFWRTPLPEIDLDIELEQNSGGKP
Sbjct: 421 NENDKKPGNYKSMLRPEVGTTSQDSALLDQELYNSFHFWRTPLPEIDLDIELEQNSGGKP 480
Query: 481 SPEGPEEESEGPVPSSPNITMATRKELEEMIENLEPHIDDPDVKAQVEVLSAALRASSLD 540
SPEGPEEESEGPVPSSPNITMATRKELEEMIENLEPHIDDPDVKAQVEVLSAALRASSLD
Sbjct: 481 SPEGPEEESEGPVPSSPNITMATRKELEEMIENLEPHIDDPDVKAQVEVLSAALRASSLD 540
Query: 541 AHEETISIEKRSDLQDELDINELPNCKINQEDSVPLISDAVENMDSTLHYIHSDSDLSNN 600
AHEETISIEKRSDLQDELDINELPNCKINQEDSVPLISDAVENMDSTLHYIHSDSDLSNN
Sbjct: 541 AHEETISIEKRSDLQDELDINELPNCKINQEDSVPLISDAVENMDSTLHYIHSDSDLSNN 600
Query: 601 SSFSPDEERRTKVQDVVPQALLDQYLSMTDPSRAQTVDTEIAKHCAYSLPGVALTLGRQN 660
SSFSPDEERRTKVQDVVPQALLDQYLSMTDPSRAQTVDTEIAKHCAYSLPGVALTLGRQN
Sbjct: 601 SSFSPDEERRTKVQDVVPQALLDQYLSMTDPSRAQTVDTEIAKHCAYSLPGVALTLGRQN 660
Query: 661 WHCLRETYETLASDMQWKVRRTLAFSIHELAVILGDQLTAADLVPIFNGFLKDLDEVRIG 720
WHCLRETYETLASDMQWKVRRTLAFSIHELAVILGDQLTAADLVPIFNGFLKDLDEVRIG
Sbjct: 661 WHCLRETYETLASDMQWKVRRTLAFSIHELAVILGDQLTAADLVPIFNGFLKDLDEVRIG 720
Query: 721 VLKHLHDFLKLLHIDKRREYLYQLQEFLVTDNSRNWRFRAELAEQLILLLELYSPRDVYD 780
VLKHLHDFLKLLHIDKRREYLYQLQEFLVTDNSRNWRFRAELAEQLILLLELYSPRDVYD
Sbjct: 721 VLKHLHDFLKLLHIDKRREYLYQLQEFLVTDNSRNWRFRAELAEQLILLLELYSPRDVYD 780
Query: 781 YLRPIALNLCADKVSSVRWISYKLVSEMVKKLHAATPPTFGVDLINELVENFGRCPKWSG 840
YLRPIALNLCADKVSSVRWISYKLVSEMVKKLHAATPPTFGVDLINELVENFGRCPKWSG
Sbjct: 781 YLRPIALNLCADKVSSVRWISYKLVSEMVKKLHAATPPTFGVDLINELVENFGRCPKWSG 840
Query: 841 RQAFVFVCQTVIEDDCLPMDQFAVHLMPHLLTLANDRVPNVRVLLAKTLRQTLLEKDYFL 900
RQAFVFVCQTVIEDDCLPMDQFAVHLMPHLLTLANDRVPNVRVLLAKTLRQTLLEKDYFL
Sbjct: 841 RQAFVFVCQTVIEDDCLPMDQFAVHLMPHLLTLANDRVPNVRVLLAKTLRQTLLEKDYFL 900
Query: 901 ASASCHQEAVEQTIMALQMDRDSDVKYFASIHPASTKISEDAMSTASSTY 950
ASASCHQEAVEQTIMALQMDRDSDVKYFASIHPASTKISEDAMSTASSTY
Sbjct: 901 ASASCHQEAVEQTIMALQMDRDSDVKYFASIHPASTKISEDAMSTASSTY 950
>gi|4826934 protein phosphatase 4, regulatory subunit 1 isoform b
[Homo sapiens]
Length = 933
Score = 1842 bits (4772), Expect = 0.0
Identities = 932/950 (98%), Positives = 933/950 (98%), Gaps = 17/950 (1%)
Query: 1 MADLSLLQEDLQEDADGFGVDDYSSESDVIIIPSALDFVSQDEMLTPLGRLDKYAASENI 60
MADLSLLQEDLQEDADG +LDFVSQDEMLTPLGRLDKYAASENI
Sbjct: 1 MADLSLLQEDLQEDADG-----------------SLDFVSQDEMLTPLGRLDKYAASENI 43
Query: 61 FNRQMVARSLLDTLREVCDDERDCIAVLERISRLADDSEPTVRAELMEQVPHIALFCQEN 120
FNRQMVARSLLDTLREVCDDERDCIAVLERISRLADDSEPTVRAELMEQVPHIALFCQEN
Sbjct: 44 FNRQMVARSLLDTLREVCDDERDCIAVLERISRLADDSEPTVRAELMEQVPHIALFCQEN 103
Query: 121 RPSIPYAFSKFLLPIVVRYLADQNNQVRKTSQAALLALLEQELIERFDVETKVCPVLIEL 180
RPSIPYAFSKFLLPIVVRYLADQNNQVRKTSQAALLALLEQELIERFDVETKVCPVLIEL
Sbjct: 104 RPSIPYAFSKFLLPIVVRYLADQNNQVRKTSQAALLALLEQELIERFDVETKVCPVLIEL 163
Query: 181 TAPDSNDDVKTEAVAIMCKMAPMVGKDITERLILPRFCEMCCDCRMFHVRKVCAANFGDI 240
TAPDSNDDVKTEAVAIMCKMAPMVGKDITERLILPRFCEMCCDCRMFHVRKVCAANFGDI
Sbjct: 164 TAPDSNDDVKTEAVAIMCKMAPMVGKDITERLILPRFCEMCCDCRMFHVRKVCAANFGDI 223
Query: 241 CSVVGQQATEEMLLPRFFQLCSDNVWGVRKACAECFMAVSCATCQEIRRTKLSALFINLI 300
CSVVGQQATEEMLLPRFFQLCSDNVWGVRKACAECFMAVSCATCQEIRRTKLSALFINLI
Sbjct: 224 CSVVGQQATEEMLLPRFFQLCSDNVWGVRKACAECFMAVSCATCQEIRRTKLSALFINLI 283
Query: 301 SDPSRWVRQAAFQSLGPFISTFANPSSSGQYFKEESKSSEEMSVENKNRTRDQEAPEDVQ 360
SDPSRWVRQAAFQSLGPFISTFANPSSSGQYFKEESKSSEEMSVENKNRTRDQEAPEDVQ
Sbjct: 284 SDPSRWVRQAAFQSLGPFISTFANPSSSGQYFKEESKSSEEMSVENKNRTRDQEAPEDVQ 343
Query: 361 VRPEDTPSDLSVSNSSVILENTMEDHAAEASGKPLGEISVPLDSSLLCTLSSESHQEAAS 420
VRPEDTPSDLSVSNSSVILENTMEDHAAEASGKPLGEISVPLDSSLLCTLSSESHQEAAS
Sbjct: 344 VRPEDTPSDLSVSNSSVILENTMEDHAAEASGKPLGEISVPLDSSLLCTLSSESHQEAAS 403
Query: 421 NENDKKPGNYKSMLRPEVGTTSQDSALLDQELYNSFHFWRTPLPEIDLDIELEQNSGGKP 480
NENDKKPGNYKSMLRPEVGTTSQDSALLDQELYNSFHFWRTPLPEIDLDIELEQNSGGKP
Sbjct: 404 NENDKKPGNYKSMLRPEVGTTSQDSALLDQELYNSFHFWRTPLPEIDLDIELEQNSGGKP 463
Query: 481 SPEGPEEESEGPVPSSPNITMATRKELEEMIENLEPHIDDPDVKAQVEVLSAALRASSLD 540
SPEGPEEESEGPVPSSPNITMATRKELEEMIENLEPHIDDPDVKAQVEVLSAALRASSLD
Sbjct: 464 SPEGPEEESEGPVPSSPNITMATRKELEEMIENLEPHIDDPDVKAQVEVLSAALRASSLD 523
Query: 541 AHEETISIEKRSDLQDELDINELPNCKINQEDSVPLISDAVENMDSTLHYIHSDSDLSNN 600
AHEETISIEKRSDLQDELDINELPNCKINQEDSVPLISDAVENMDSTLHYIHSDSDLSNN
Sbjct: 524 AHEETISIEKRSDLQDELDINELPNCKINQEDSVPLISDAVENMDSTLHYIHSDSDLSNN 583
Query: 601 SSFSPDEERRTKVQDVVPQALLDQYLSMTDPSRAQTVDTEIAKHCAYSLPGVALTLGRQN 660
SSFSPDEERRTKVQDVVPQALLDQYLSMTDPSRAQTVDTEIAKHCAYSLPGVALTLGRQN
Sbjct: 584 SSFSPDEERRTKVQDVVPQALLDQYLSMTDPSRAQTVDTEIAKHCAYSLPGVALTLGRQN 643
Query: 661 WHCLRETYETLASDMQWKVRRTLAFSIHELAVILGDQLTAADLVPIFNGFLKDLDEVRIG 720
WHCLRETYETLASDMQWKVRRTLAFSIHELAVILGDQLTAADLVPIFNGFLKDLDEVRIG
Sbjct: 644 WHCLRETYETLASDMQWKVRRTLAFSIHELAVILGDQLTAADLVPIFNGFLKDLDEVRIG 703
Query: 721 VLKHLHDFLKLLHIDKRREYLYQLQEFLVTDNSRNWRFRAELAEQLILLLELYSPRDVYD 780
VLKHLHDFLKLLHIDKRREYLYQLQEFLVTDNSRNWRFRAELAEQLILLLELYSPRDVYD
Sbjct: 704 VLKHLHDFLKLLHIDKRREYLYQLQEFLVTDNSRNWRFRAELAEQLILLLELYSPRDVYD 763
Query: 781 YLRPIALNLCADKVSSVRWISYKLVSEMVKKLHAATPPTFGVDLINELVENFGRCPKWSG 840
YLRPIALNLCADKVSSVRWISYKLVSEMVKKLHAATPPTFGVDLINELVENFGRCPKWSG
Sbjct: 764 YLRPIALNLCADKVSSVRWISYKLVSEMVKKLHAATPPTFGVDLINELVENFGRCPKWSG 823
Query: 841 RQAFVFVCQTVIEDDCLPMDQFAVHLMPHLLTLANDRVPNVRVLLAKTLRQTLLEKDYFL 900
RQAFVFVCQTVIEDDCLPMDQFAVHLMPHLLTLANDRVPNVRVLLAKTLRQTLLEKDYFL
Sbjct: 824 RQAFVFVCQTVIEDDCLPMDQFAVHLMPHLLTLANDRVPNVRVLLAKTLRQTLLEKDYFL 883
Query: 901 ASASCHQEAVEQTIMALQMDRDSDVKYFASIHPASTKISEDAMSTASSTY 950
ASASCHQEAVEQTIMALQMDRDSDVKYFASIHPASTKISEDAMSTASSTY
Sbjct: 884 ASASCHQEAVEQTIMALQMDRDSDVKYFASIHPASTKISEDAMSTASSTY 933
>gi|21361399 alpha isoform of regulatory subunit A, protein
phosphatase 2 [Homo sapiens]
Length = 589
Score = 73.2 bits (178), Expect = 1e-12
Identities = 114/454 (25%), Positives = 183/454 (40%), Gaps = 51/454 (11%)
Query: 497 PNITMATRKELEEMIENLEPHIDDPDVK-AQVEVLSAALRASSLD-AHEETISIEKR--S 552
P ++ A + EL + NL D P V+ A L + LD E I + S
Sbjct: 156 PRVSSAVKAELRQYFRNLCSD-DTPMVRRAAASKLGEFAKVLELDNVKSEIIPMFSNLAS 214
Query: 553 DLQDELDINELPNCK-----INQEDS----VPLISDAVENMDSTLHYIHSDSDLSNNSSF 603
D QD + + + C + QED +P + A E+ + Y+ +D +
Sbjct: 215 DEQDSVRLLAVEACVNIAQLLPQEDLEALVMPTLRQAAEDKSWRVRYMVADKFTELQKAV 274
Query: 604 SPDEERRTKVQDVVP--QALLDQYLSMTDPSRAQTVDTEIAKHCAYSLPGVALTLGRQNW 661
P+ + D+VP Q L+ + + + V A V ++ Q
Sbjct: 275 GPEITKT----DLVPAFQNLMKDCEAEVRAAASHKVKEFCENLSADCRENVIMS---QIL 327
Query: 662 HCLRETYETLASDMQWKVRRTLAFSIHELAVILGDQLTAADLVPIFNGFLKD-LDEVRIG 720
C++E L SD V+ LA I L+ ILG T L+P+F LKD EVR+
Sbjct: 328 PCIKE----LVSDANQHVKSALASVIMGLSPILGKDNTIEHLLPLFLAQLKDECPEVRLN 383
Query: 721 VLKHLHDFLKLLHIDKRREYLYQLQEFLVTDNSRNWRFRAELAEQLILLLELYSPRDVYD 780
++ +L +++ I + + L L D WR R + E + LL +
Sbjct: 384 IISNLDCVNEVIGIRQLSQSLLPAIVELAED--AKWRVRLAIIEYMPLLAGQLGVEFFDE 441
Query: 781 YLRPIALNLCADKVSSVRWISYKLVSEMVKKL-----HAATPPTFGVDLINELVENFGRC 835
L + + D V ++R + + ++V+K HA P V
Sbjct: 442 KLNSLCMAWLVDHVYAIREAATSNLKKLVEKFGKEWAHATIIPK---------VLAMSGD 492
Query: 836 PKWSGRQAFVFVCQTVIEDDCLPMDQFAVHLMPHLLTLANDRVPNVRVLLAKTLRQTLLE 895
P + R +F C V+ + C D H++P +L +A D V NVR +AK+ L+
Sbjct: 493 PNYLHRMTTLF-CINVLSEVC-GQDITTKHMLPTVLRMAGDPVANVRFNVAKS-----LQ 545
Query: 896 KDYFLASASCHQEAVEQTIMALQMDRDSDVKYFA 929
K + S Q V+ + L D+D DVKYFA
Sbjct: 546 KIGPILDNSTLQSEVKPILEKLTQDQDVDVKYFA 579
Score = 55.8 bits (133), Expect = 2e-07
Identities = 41/154 (26%), Positives = 73/154 (47%), Gaps = 2/154 (1%)
Query: 169 VETKVCPVLIELTAPDSNDDVKTEAVAIMCKMAPMVGKDITERLILPRFCEMCCDCRMFH 228
+ +++ P + EL + D+N VK+ +++ ++P++GKD T +LP F D
Sbjct: 322 IMSQILPCIKELVS-DANQHVKSALASVIMGLSPILGKDNTIEHLLPLFLAQLKD-ECPE 379
Query: 229 VRKVCAANFGDICSVVGQQATEEMLLPRFFQLCSDNVWGVRKACAECFMAVSCATCQEIR 288
VR +N + V+G + + LLP +L D W VR A E ++ E
Sbjct: 380 VRLNIISNLDCVNEVIGIRQLSQSLLPAIVELAEDAKWRVRLAIIEYMPLLAGQLGVEFF 439
Query: 289 RTKLSALFINLISDPSRWVRQAAFQSLGPFISTF 322
KL++L + + D +R+AA +L + F
Sbjct: 440 DEKLNSLCMAWLVDHVYAIREAATSNLKKLVEKF 473
Score = 48.9 bits (115), Expect = 2e-05
Identities = 56/232 (24%), Positives = 93/232 (40%), Gaps = 11/232 (4%)
Query: 87 VLERISRLADDSEPTVRAELMEQVPHIALFCQENRPSIPYAFSKFLLPIVVRYLADQNNQ 146
+L + LA E VR + +E + I+ E+ PS +P+V R LA +
Sbjct: 89 LLPPLESLATVEETVVRDKAVESLRAIS---HEHSPS---DLEAHFVPLVKR-LAGGDWF 141
Query: 147 VRKTSQAALLALLEQELIERFDVETKVCPVLIELTAPDSNDDVKTEAVAIMCKMAPMVGK 206
+TS L ++ + E + D V+ A + + + A ++
Sbjct: 142 TSRTSACGLFSVCYPRVSSAVKAELRQ---YFRNLCSDDTPMVRRAAASKLGEFAKVLEL 198
Query: 207 DITERLILPRFCEMCCDCRMFHVRKVCAANFGDICSVVGQQATEEMLLPRFFQLCSDNVW 266
D + I+P F + D VR + +I ++ Q+ E +++P Q D W
Sbjct: 199 DNVKSEIIPMFSNLASD-EQDSVRLLAVEACVNIAQLLPQEDLEALVMPTLRQAAEDKSW 257
Query: 267 GVRKACAECFMAVSCATCQEIRRTKLSALFINLISDPSRWVRQAAFQSLGPF 318
VR A+ F + A EI +T L F NL+ D VR AA + F
Sbjct: 258 RVRYMVADKFTELQKAVGPEITKTDLVPAFQNLMKDCEAEVRAAASHKVKEF 309
Score = 37.7 bits (86), Expect = 0.051
Identities = 47/222 (21%), Positives = 83/222 (37%), Gaps = 11/222 (4%)
Query: 100 PTVRAELMEQVPHIALFCQENRPSIPYAF-----SKFLLPIVVRYLADQNNQVRKTSQAA 154
P A+L ++ P + L N + S+ LLP +V D +VR
Sbjct: 367 PLFLAQLKDECPEVRLNIISNLDCVNEVIGIRQLSQSLLPAIVELAEDAKWRVRLAIIEY 426
Query: 155 LLALLEQELIERFDVE-TKVCPVLIELTAPDSNDDVKTEAVAIMCKMAPMVGKDITERLI 213
+ L Q +E FD + +C + D ++ A + + K+ GK+ I
Sbjct: 427 MPLLAGQLGVEFFDEKLNSLCMAWLV----DHVYAIREAATSNLKKLVEKFGKEWAHATI 482
Query: 214 LPRFCEMCCDCRMFHVRKVCAANFGDICSVVGQQATEEMLLPRFFQLCSDNVWGVRKACA 273
+P+ M D H R + V GQ T + +LP ++ D V VR A
Sbjct: 483 IPKVLAMSGDPNYLH-RMTTLFCINVLSEVCGQDITTKHMLPTVLRMAGDPVANVRFNVA 541
Query: 274 ECFMAVSCATCQEIRRTKLSALFINLISDPSRWVRQAAFQSL 315
+ + ++++ + L D V+ A ++L
Sbjct: 542 KSLQKIGPILDNSTLQSEVKPILEKLTQDQDVDVKYFAQEAL 583
Score = 37.0 bits (84), Expect = 0.087
Identities = 48/256 (18%), Positives = 101/256 (39%), Gaps = 20/256 (7%)
Query: 74 LREVCDD-ERDC------IAVLERISRLADDSEPTVRAELMEQVPHIALFCQENRPSIPY 126
++E C++ DC +L I L D+ V++ L + ++ ++
Sbjct: 306 VKEFCENLSADCRENVIMSQILPCIKELVSDANQHVKSALASVIMGLSPILGKDNTI--- 362
Query: 127 AFSKFLLPIVVRYLADQNNQVRKTSQAALLALLEQELIERFDVETKVCPVLIELTAPDSN 186
+ LLP+ + L D+ +VR + L + E+I + + P ++EL A D+
Sbjct: 363 ---EHLLPLFLAQLKDECPEVRLNIISNLDCV--NEVIGIRQLSQSLLPAIVEL-AEDAK 416
Query: 187 DDVKTEAVAIMCKMAPMVGKDITERLILPRFCEMCCDCRMFHVRKVCAANFGDICSVVGQ 246
V+ + M +A +G + + L C ++ +R+ +N + G+
Sbjct: 417 WRVRLAIIEYMPLLAGQLGVEFFDEK-LNSLCMAWLVDHVYAIREAATSNLKKLVEKFGK 475
Query: 247 QATEEMLLPRFFQLCSDNVWGVRKACAECFMAVSCATCQEIRRTKLSALFINLISDPSRW 306
+ ++P+ + D + R C +S Q+I + + + DP
Sbjct: 476 EWAHATIIPKVLAMSGDPNYLHRMTTLFCINVLSEVCGQDITTKHMLPTVLRMAGDPVAN 535
Query: 307 VR---QAAFQSLGPFI 319
VR + Q +GP +
Sbjct: 536 VRFNVAKSLQKIGPIL 551
Score = 33.1 bits (74), Expect = 1.3
Identities = 52/252 (20%), Positives = 97/252 (38%), Gaps = 13/252 (5%)
Query: 690 LAVILGDQLTAADLVPIFNGFLKDLDEVRIGVLKHLHDFLKLLHIDKRREYLYQLQEFLV 749
+A+ LG + T ++L+P + D DEV + + + L F L+ + L E L
Sbjct: 38 IALALGVERTRSELLPFLTDTIYDEDEVLLALAEQLGTFTTLVGGPEYVHCLLPPLESLA 97
Query: 750 TDNSRNWRFRAELAEQLILLLELYSPRDVYDYLRPIALNLCADKVSSVRWISYKLVSEMV 809
T R +A E L + +SP D+ + P+ L + R + L S
Sbjct: 98 TVEETVVRDKA--VESLRAISHEHSPSDLEAHFVPLVKRLAGGDWFTSRTSACGLFSVCY 155
Query: 810 KKLHAATPPTFGVDLINELVENFGRCPKWSGRQAFVFVCQTVIEDDCLPMDQFAVHLMPH 869
++ +A N ++ + + + F L +D ++P
Sbjct: 156 PRVSSAVKAELRQYFRNLCSDDTPMVRRAAASKLGEFA-------KVLELDNVKSEIIPM 208
Query: 870 LLTLANDRVPNVRVLLAK---TLRQTLLEKDY-FLASASCHQEAVEQTIMALQMDRDSDV 925
LA+D +VR+L + + Q L ++D L + Q A +++ M D
Sbjct: 209 FSNLASDEQDSVRLLAVEACVNIAQLLPQEDLEALVMPTLRQAAEDKSWRVRYMVADKFT 268
Query: 926 KYFASIHPASTK 937
+ ++ P TK
Sbjct: 269 ELQKAVGPEITK 280
>gi|32455246 beta isoform of regulatory subunit A, protein
phosphatase 2 isoform a [Homo sapiens]
Length = 601
Score = 65.1 bits (157), Expect = 3e-10
Identities = 66/260 (25%), Positives = 113/260 (43%), Gaps = 14/260 (5%)
Query: 671 LASDMQWKVRRTLAFSIHELAVILGDQLTAADLVPIFNGFLKD-LDEVRIGVLKHLHDFL 729
L SD V+ LA I L+ ILG + T L+P+F LKD +VR+ ++ +L
Sbjct: 345 LVSDTNQHVKSALASVIMGLSTILGKENTIEHLLPLFLAQLKDECPDVRLNIISNLDCVN 404
Query: 730 KLLHIDKRREYLYQLQEFLVTDNSRNWRFRAELAEQLILLLELYSPRDVYDYLRPIALNL 789
+++ I + + L L D WR R + E + LL + L + +
Sbjct: 405 EVIGIRQLSQSLLPAIVELAED--AKWRVRLAIIEYMPLLAGQLGVEFFDEKLNSLCMAW 462
Query: 790 CADKVSSVRWISYKLVSEMVKKLHAATPPTFGVDLINELVENFGRCPKWSGRQAFVFVCQ 849
D V ++R + + ++V+K V + + + P + R +F C
Sbjct: 463 LVDHVYAIREAATNNLMKLVQKFGTEWAQNTIVPKVLVMAND----PNYLHRMTTLF-CI 517
Query: 850 TVIEDDCLPMDQFAVHLMPHLLTLANDRVPNVRVLLAKTLRQTLLEKDYFLASASCHQEA 909
+ + C + ++P +L +A D+V NVR +AK+ L+K + + Q
Sbjct: 518 NALSEAC-GQEITTKQMLPIVLKMAGDQVANVRFNVAKS-----LQKIGPILDTNALQGE 571
Query: 910 VEQTIMALQMDRDSDVKYFA 929
V+ + L D D DVKYFA
Sbjct: 572 VKPVLQKLGQDEDMDVKYFA 591
Score = 55.5 bits (132), Expect = 2e-07
Identities = 66/303 (21%), Positives = 121/303 (39%), Gaps = 24/303 (7%)
Query: 40 SQDEMLTPLGRLDKYAASENIFNRQMVARSLLDTLREVCDDERD---------CIAVLER 90
S D + K + V ++ + DE+D C+++ +
Sbjct: 187 SDDTPMVRRAAASKLGEFAKVLELDSVKSEIVPLFTSLASDEQDSVRLLAVEACVSIAQL 246
Query: 91 ISRLADDSE----PTVRAELMEQVPHIAL-----FCQENRPSIPYAFSKFLLPIVVRYLA 141
+S+ DD E PT+R ++ + F + + P L+P L
Sbjct: 247 LSQ--DDLETLVMPTLRQAAEDKSWRVRYMVADRFSELQKAMGPKITLNDLIPAFQNLLK 304
Query: 142 DQNNQVRKTSQAALLALLEQELIERFD--VETKVCPVLIELTAPDSNDDVKTEAVAIMCK 199
D +VR + + L E IE + + ++ P + EL + D+N VK+ +++
Sbjct: 305 DCEAEVRAAAAHKVKELGENLPIEDRETIIMNQILPYIKELVS-DTNQHVKSALASVIMG 363
Query: 200 MAPMVGKDITERLILPRFCEMCCDCRMFHVRKVCAANFGDICSVVGQQATEEMLLPRFFQ 259
++ ++GK+ T +LP F D VR +N + V+G + + LLP +
Sbjct: 364 LSTILGKENTIEHLLPLFLAQLKD-ECPDVRLNIISNLDCVNEVIGIRQLSQSLLPAIVE 422
Query: 260 LCSDNVWGVRKACAECFMAVSCATCQEIRRTKLSALFINLISDPSRWVRQAAFQSLGPFI 319
L D W VR A E ++ E KL++L + + D +R+AA +L +
Sbjct: 423 LAEDAKWRVRLAIIEYMPLLAGQLGVEFFDEKLNSLCMAWLVDHVYAIREAATNNLMKLV 482
Query: 320 STF 322
F
Sbjct: 483 QKF 485
Score = 51.6 bits (122), Expect = 3e-06
Identities = 57/231 (24%), Positives = 94/231 (40%), Gaps = 13/231 (5%)
Query: 664 LRETYETLASDMQWKVRRTLAFSIHELAVILGDQLTAADLVPIFNGFLKD-LDEVRIGVL 722
+R+ + +L SD VRR A + E A +L +++VP+F D D VR+ +
Sbjct: 178 IRQQFRSLCSDDTPMVRRAAASKLGEFAKVLELDSVKSEIVPLFTSLASDEQDSVRLLAV 237
Query: 723 KHLHDFLKLLHIDKRREYLYQLQEFLVTDNSRNWRFRAELAEQLILLLELYSPRDVYDYL 782
+ +LL D + D S WR R +A++ L + P+ + L
Sbjct: 238 EACVSIAQLLSQDDLETLVMPTLRQAAEDKS--WRVRYMVADRFSELQKAMGPKITLNDL 295
Query: 783 RPIALNLCADKVSSVRWISYKLVSEMVKKLHAATPPTFGVD----LINELVENFGRCPKW 838
P NL D + VR + V E+ + L T ++ I ELV + + K
Sbjct: 296 IPAFQNLLKDCEAEVRAAAAHKVKELGENLPIEDRETIIMNQILPYIKELVSDTNQHVK- 354
Query: 839 SGRQAFVFVCQTVIEDDCLPMDQFAVHLMPHLLTLANDRVPNVRVLLAKTL 889
S + + T+ L + HL+P L D P+VR+ + L
Sbjct: 355 SALASVIMGLSTI-----LGKENTIEHLLPLFLAQLKDECPDVRLNIISNL 400
Score = 47.0 bits (110), Expect = 8e-05
Identities = 54/225 (24%), Positives = 88/225 (39%), Gaps = 11/225 (4%)
Query: 87 VLERISRLADDSEPTVRAELMEQVPHIALFCQENRPSIPYAFSKFLLPIVVRYLADQNNQ 146
+L + LA E VR + +E + I+ QE+ P A + +P+V R LA +
Sbjct: 101 LLPPLENLATVEETVVRDKAVESLRQIS---QEHTP---VALEAYFVPLVKR-LASGDWF 153
Query: 147 VRKTSQAALLALLEQELIERFDVETKVCPVLIELTAPDSNDDVKTEAVAIMCKMAPMVGK 206
+TS L ++ E + D V+ A + + + A ++
Sbjct: 154 TSRTSACGLFSVCYPRASNAVKAEIRQ---QFRSLCSDDTPMVRRAAASKLGEFAKVLEL 210
Query: 207 DITERLILPRFCEMCCDCRMFHVRKVCAANFGDICSVVGQQATEEMLLPRFFQLCSDNVW 266
D + I+P F + D VR + I ++ Q E +++P Q D W
Sbjct: 211 DSVKSEIVPLFTSLASD-EQDSVRLLAVEACVSIAQLLSQDDLETLVMPTLRQAAEDKSW 269
Query: 267 GVRKACAECFMAVSCATCQEIRRTKLSALFINLISDPSRWVRQAA 311
VR A+ F + A +I L F NL+ D VR AA
Sbjct: 270 RVRYMVADRFSELQKAMGPKITLNDLIPAFQNLLKDCEAEVRAAA 314
Score = 34.7 bits (78), Expect = 0.43
Identities = 39/176 (22%), Positives = 66/176 (37%), Gaps = 11/176 (6%)
Query: 100 PTVRAELMEQVPHIALFCQENRPSIPYAF-----SKFLLPIVVRYLADQNNQVRKTSQAA 154
P A+L ++ P + L N + S+ LLP +V D +VR
Sbjct: 379 PLFLAQLKDECPDVRLNIISNLDCVNEVIGIRQLSQSLLPAIVELAEDAKWRVRLAIIEY 438
Query: 155 LLALLEQELIERFDVE-TKVCPVLIELTAPDSNDDVKTEAVAIMCKMAPMVGKDITERLI 213
+ L Q +E FD + +C + D ++ A + K+ G + + I
Sbjct: 439 MPLLAGQLGVEFFDEKLNSLCMAWLV----DHVYAIREAATNNLMKLVQKFGTEWAQNTI 494
Query: 214 LPRFCEMCCDCRMFHVRKVCAANFGDICSVVGQQATEEMLLPRFFQLCSDNVWGVR 269
+P+ M D H R + GQ+ T + +LP ++ D V VR
Sbjct: 495 VPKVLVMANDPNYLH-RMTTLFCINALSEACGQEITTKQMLPIVLKMAGDQVANVR 549
>gi|32455244 beta isoform of regulatory subunit A, protein
phosphatase 2 isoform b [Homo sapiens]
Length = 667
Score = 65.1 bits (157), Expect = 3e-10
Identities = 66/260 (25%), Positives = 113/260 (43%), Gaps = 14/260 (5%)
Query: 671 LASDMQWKVRRTLAFSIHELAVILGDQLTAADLVPIFNGFLKD-LDEVRIGVLKHLHDFL 729
L SD V+ LA I L+ ILG + T L+P+F LKD +VR+ ++ +L
Sbjct: 345 LVSDTNQHVKSALASVIMGLSTILGKENTIEHLLPLFLAQLKDECPDVRLNIISNLDCVN 404
Query: 730 KLLHIDKRREYLYQLQEFLVTDNSRNWRFRAELAEQLILLLELYSPRDVYDYLRPIALNL 789
+++ I + + L L D WR R + E + LL + L + +
Sbjct: 405 EVIGIRQLSQSLLPAIVELAED--AKWRVRLAIIEYMPLLAGQLGVEFFDEKLNSLCMAW 462
Query: 790 CADKVSSVRWISYKLVSEMVKKLHAATPPTFGVDLINELVENFGRCPKWSGRQAFVFVCQ 849
D V ++R + + ++V+K V + + + P + R +F C
Sbjct: 463 LVDHVYAIREAATNNLMKLVQKFGTEWAQNTIVPKVLVMAND----PNYLHRMTTLF-CI 517
Query: 850 TVIEDDCLPMDQFAVHLMPHLLTLANDRVPNVRVLLAKTLRQTLLEKDYFLASASCHQEA 909
+ + C + ++P +L +A D+V NVR +AK+ L+K + + Q
Sbjct: 518 NALSEAC-GQEITTKQMLPIVLKMAGDQVANVRFNVAKS-----LQKIGPILDTNALQGE 571
Query: 910 VEQTIMALQMDRDSDVKYFA 929
V+ + L D D DVKYFA
Sbjct: 572 VKPVLQKLGQDEDMDVKYFA 591
Score = 55.5 bits (132), Expect = 2e-07
Identities = 66/303 (21%), Positives = 121/303 (39%), Gaps = 24/303 (7%)
Query: 40 SQDEMLTPLGRLDKYAASENIFNRQMVARSLLDTLREVCDDERD---------CIAVLER 90
S D + K + V ++ + DE+D C+++ +
Sbjct: 187 SDDTPMVRRAAASKLGEFAKVLELDSVKSEIVPLFTSLASDEQDSVRLLAVEACVSIAQL 246
Query: 91 ISRLADDSE----PTVRAELMEQVPHIAL-----FCQENRPSIPYAFSKFLLPIVVRYLA 141
+S+ DD E PT+R ++ + F + + P L+P L
Sbjct: 247 LSQ--DDLETLVMPTLRQAAEDKSWRVRYMVADRFSELQKAMGPKITLNDLIPAFQNLLK 304
Query: 142 DQNNQVRKTSQAALLALLEQELIERFD--VETKVCPVLIELTAPDSNDDVKTEAVAIMCK 199
D +VR + + L E IE + + ++ P + EL + D+N VK+ +++
Sbjct: 305 DCEAEVRAAAAHKVKELGENLPIEDRETIIMNQILPYIKELVS-DTNQHVKSALASVIMG 363
Query: 200 MAPMVGKDITERLILPRFCEMCCDCRMFHVRKVCAANFGDICSVVGQQATEEMLLPRFFQ 259
++ ++GK+ T +LP F D VR +N + V+G + + LLP +
Sbjct: 364 LSTILGKENTIEHLLPLFLAQLKD-ECPDVRLNIISNLDCVNEVIGIRQLSQSLLPAIVE 422
Query: 260 LCSDNVWGVRKACAECFMAVSCATCQEIRRTKLSALFINLISDPSRWVRQAAFQSLGPFI 319
L D W VR A E ++ E KL++L + + D +R+AA +L +
Sbjct: 423 LAEDAKWRVRLAIIEYMPLLAGQLGVEFFDEKLNSLCMAWLVDHVYAIREAATNNLMKLV 482
Query: 320 STF 322
F
Sbjct: 483 QKF 485
Score = 51.6 bits (122), Expect = 3e-06
Identities = 57/231 (24%), Positives = 94/231 (40%), Gaps = 13/231 (5%)
Query: 664 LRETYETLASDMQWKVRRTLAFSIHELAVILGDQLTAADLVPIFNGFLKD-LDEVRIGVL 722
+R+ + +L SD VRR A + E A +L +++VP+F D D VR+ +
Sbjct: 178 IRQQFRSLCSDDTPMVRRAAASKLGEFAKVLELDSVKSEIVPLFTSLASDEQDSVRLLAV 237
Query: 723 KHLHDFLKLLHIDKRREYLYQLQEFLVTDNSRNWRFRAELAEQLILLLELYSPRDVYDYL 782
+ +LL D + D S WR R +A++ L + P+ + L
Sbjct: 238 EACVSIAQLLSQDDLETLVMPTLRQAAEDKS--WRVRYMVADRFSELQKAMGPKITLNDL 295
Query: 783 RPIALNLCADKVSSVRWISYKLVSEMVKKLHAATPPTFGVD----LINELVENFGRCPKW 838
P NL D + VR + V E+ + L T ++ I ELV + + K
Sbjct: 296 IPAFQNLLKDCEAEVRAAAAHKVKELGENLPIEDRETIIMNQILPYIKELVSDTNQHVK- 354
Query: 839 SGRQAFVFVCQTVIEDDCLPMDQFAVHLMPHLLTLANDRVPNVRVLLAKTL 889
S + + T+ L + HL+P L D P+VR+ + L
Sbjct: 355 SALASVIMGLSTI-----LGKENTIEHLLPLFLAQLKDECPDVRLNIISNL 400
Score = 47.0 bits (110), Expect = 8e-05
Identities = 54/225 (24%), Positives = 88/225 (39%), Gaps = 11/225 (4%)
Query: 87 VLERISRLADDSEPTVRAELMEQVPHIALFCQENRPSIPYAFSKFLLPIVVRYLADQNNQ 146
+L + LA E VR + +E + I+ QE+ P A + +P+V R LA +
Sbjct: 101 LLPPLENLATVEETVVRDKAVESLRQIS---QEHTP---VALEAYFVPLVKR-LASGDWF 153
Query: 147 VRKTSQAALLALLEQELIERFDVETKVCPVLIELTAPDSNDDVKTEAVAIMCKMAPMVGK 206
+TS L ++ E + D V+ A + + + A ++
Sbjct: 154 TSRTSACGLFSVCYPRASNAVKAEIRQ---QFRSLCSDDTPMVRRAAASKLGEFAKVLEL 210
Query: 207 DITERLILPRFCEMCCDCRMFHVRKVCAANFGDICSVVGQQATEEMLLPRFFQLCSDNVW 266
D + I+P F + D VR + I ++ Q E +++P Q D W
Sbjct: 211 DSVKSEIVPLFTSLASD-EQDSVRLLAVEACVSIAQLLSQDDLETLVMPTLRQAAEDKSW 269
Query: 267 GVRKACAECFMAVSCATCQEIRRTKLSALFINLISDPSRWVRQAA 311
VR A+ F + A +I L F NL+ D VR AA
Sbjct: 270 RVRYMVADRFSELQKAMGPKITLNDLIPAFQNLLKDCEAEVRAAA 314
Score = 34.7 bits (78), Expect = 0.43
Identities = 39/176 (22%), Positives = 66/176 (37%), Gaps = 11/176 (6%)
Query: 100 PTVRAELMEQVPHIALFCQENRPSIPYAF-----SKFLLPIVVRYLADQNNQVRKTSQAA 154
P A+L ++ P + L N + S+ LLP +V D +VR
Sbjct: 379 PLFLAQLKDECPDVRLNIISNLDCVNEVIGIRQLSQSLLPAIVELAEDAKWRVRLAIIEY 438
Query: 155 LLALLEQELIERFDVE-TKVCPVLIELTAPDSNDDVKTEAVAIMCKMAPMVGKDITERLI 213
+ L Q +E FD + +C + D ++ A + K+ G + + I
Sbjct: 439 MPLLAGQLGVEFFDEKLNSLCMAWLV----DHVYAIREAATNNLMKLVQKFGTEWAQNTI 494
Query: 214 LPRFCEMCCDCRMFHVRKVCAANFGDICSVVGQQATEEMLLPRFFQLCSDNVWGVR 269
+P+ M D H R + GQ+ T + +LP ++ D V VR
Sbjct: 495 VPKVLVMANDPNYLH-RMTTLFCINALSEACGQEITTKQMLPIVLKMAGDQVANVR 549
>gi|17402886 HEAT-like repeat-containing protein isoform 1 [Homo
sapiens]
Length = 873
Score = 47.4 bits (111), Expect = 6e-05
Identities = 57/265 (21%), Positives = 112/265 (42%), Gaps = 24/265 (9%)
Query: 641 IAKHCAYSLPGVALTLGRQNWHC-LRETYETLASDMQWKVRRTLAFSIHELAVIL--GDQ 697
+ K+CAY+ P + + + +N+H L T+ L D + VR T+A +E++ +L G
Sbjct: 373 VRKNCAYNFPAMIVFVDPKNFHMELYSTFFCLCHDPEVPVRYTIAICFYEVSKLLNSGVY 432
Query: 698 LTAADLVPIFNGFLKDLDEVRIGVLKHLHDFLKLLHI-------DKRREYLYQLQEFLVT 750
L +L+ + + EV ++ HL + L+L+ + + L L L
Sbjct: 433 LIHKELITLLQ---DESLEVLDALIDHLPEILELMSTGGESSVQENKLSSLPDLIPALTA 489
Query: 751 DNSR-----NWRFRAELAEQLILLLELYSPRDV-YDYLRPIALNLCADKVSSVRWISYKL 804
R WR +L ++ L + S + Y +L+ + + + V V+ + +
Sbjct: 490 AEQRAAASLKWRTHEKLLQKYACLPHVISSDQIYYRFLQRMFTIMMTNNVLPVQKAASRT 549
Query: 805 VSEMVKKLHAATPPTFGVDLINELVENFGRCPKWSGRQAFVFVCQTVIEDDCLPMDQFAV 864
+ ++ ++I +L+E G+ + R F+ C+ +IE F
Sbjct: 550 LCIFLRYNRKQEQRH---EVIQKLIEQLGQGKSYWNRLRFLDTCEFIIE--IFSKSFFCK 604
Query: 865 HLMPHLLTLANDRVPNVRVLLAKTL 889
+ + L +D V NVR+ L L
Sbjct: 605 YFFLPAIELTHDPVANVRMKLCYLL 629
Score = 38.5 bits (88), Expect = 0.030
Identities = 76/325 (23%), Positives = 121/325 (37%), Gaps = 46/325 (14%)
Query: 43 EMLTPLGRLDKYAASENIFNRQMVARSLLDTLREVCDDERDCIAVLERISRLADDSEPTV 102
E+L PL + K S+ + +R +V+ +L L D +L + L D E V
Sbjct: 172 EILNPL--VSKAQLSQTVQSR-LVSCKILGKLTNKFDAHTIKREILPLVKSLCQDVEYEV 228
Query: 103 RAELMEQVPHIALFCQENRPSIPYAFSK-FLLPIVVRYLADQNNQVRKTSQAALLALLE- 160
R+ + Q+ +IA I +K +LP ++ D+ + VR + L+ LL+
Sbjct: 229 RSCMCRQLENIA-------QGIGTELTKSVVLPELIELSRDEGSSVRLAAFETLVNLLDI 281
Query: 161 ----------QELIERFDVET----------------KVCPVLIELTAPDSNDDVKTEAV 194
L++ F ++ K+C L + PD + E
Sbjct: 282 FDTDDRSQTILPLVKSFCEKSFKADESILISLSFHLGKLCHGLYGIFTPDQHLRF-LEFY 340
Query: 195 AIMCKMAPMVGKDITERLILPRFCEMCCDCRMFHVRKVCAANFGDICSVVGQQATEEMLL 254
+C + E I P+ E + + VRK CA NF + V + L
Sbjct: 341 KKLCTLGLQQENGHNENQIPPQILEQ--EKKYISVRKNCAYNFPAMIVFVDPKNFHMELY 398
Query: 255 PRFFQLCSDNVWGVRKACAECFMAVSCATCQEIRRTKLSALFINLISDPSRWVRQAAFQS 314
FF LC D VR A CF VS + + I L+ D S V A
Sbjct: 399 STFFCLCHDPEVPVRYTIAICFYEVSKLLNSGV--YLIHKELITLLQDESLEVLDALIDH 456
Query: 315 LGPFISTFANPSSSGQYFKEESKSS 339
L + S+ G+ +E+K S
Sbjct: 457 LPEILELM---STGGESSVQENKLS 478
>gi|24308089 chromodomain helicase DNA binding protein 5 [Homo
sapiens]
Length = 1954
Score = 40.8 bits (94), Expect = 0.006
Identities = 42/156 (26%), Positives = 71/156 (45%), Gaps = 23/156 (14%)
Query: 482 PEGPEEESEG---------PVPSSPNITMATRKELEEMIENLEPHIDDPDVKAQ------ 526
PEGPE + G PVP+SP + L + +E ++D+ D AQ
Sbjct: 1531 PEGPEGKKSGEVISSDPNTPVPASPAHLLPAPLGLPDKMEAQLGYMDEKDPGAQKPRQPL 1590
Query: 527 -VEVLSAAL-RASSLDAHEETISIEK-RSDLQDELDINELPNCKINQEDSVPLISDAVEN 583
V+ L AAL R S D HE S E+ R + +E + ++ +E+ +P ++
Sbjct: 1591 EVQALPAALDRVESEDKHESPASKERAREERPEETEKAPPSPEQLPREEVLPEKEKILDK 1650
Query: 584 MDSTLHYIHSDSDLSNNSSFSPDEERRTKVQDVVPQ 619
++ +L IHS D +S PD+ + + + + Q
Sbjct: 1651 LELSL--IHSRGD---SSELRPDDTKAEEKEPIETQ 1681
>gi|115430243 SCY1-like 1 isoform B [Homo sapiens]
Length = 791
Score = 38.5 bits (88), Expect = 0.030
Identities = 42/212 (19%), Positives = 82/212 (38%), Gaps = 7/212 (3%)
Query: 128 FSKFLLPIVVRYLADQNNQVRKTSQAALLALLEQ--ELIERFDVETKVCPVLIELTAPDS 185
+ + ++P+VV+ + + +R LL +EQ + ++ V T++ P ++ D+
Sbjct: 346 YQQKIIPVVVKMFSSTDRAMR----IRLLQQMEQFIQYLDEPTVNTQIFPHVVHGFL-DT 400
Query: 186 NDDVKTEAVAIMCKMAPMVGKDITERLILPRFCEMCCDCRMFHVRKVCAANFGDICSVVG 245
N ++ + V M +AP + + ++ F + +R G I S +
Sbjct: 401 NPAIREQTVKSMLLLAPKLNEANLNVELMKHFARLQAKDEQGPIRCNTTVCLGKIGSYLS 460
Query: 246 QQATEEMLLPRFFQLCSDNVWGVRKACAECFMAVSCATCQEIRRTKLSALFINLISDPSR 305
+L F + D R A F A K+ + L DP +
Sbjct: 461 ASTRHRVLTSAFSRATRDPFAPSRVAGVLGFAATHNLYSMNDCAQKILPVLCGLTVDPEK 520
Query: 306 WVRQAAFQSLGPFISTFANPSSSGQYFKEESK 337
VR AF+++ F+S + S +E K
Sbjct: 521 SVRDQAFKAIRSFLSKLESVSEDPTQLEEVEK 552
>gi|115430241 SCY1-like 1 isoform A [Homo sapiens]
Length = 808
Score = 38.5 bits (88), Expect = 0.030
Identities = 42/212 (19%), Positives = 82/212 (38%), Gaps = 7/212 (3%)
Query: 128 FSKFLLPIVVRYLADQNNQVRKTSQAALLALLEQ--ELIERFDVETKVCPVLIELTAPDS 185
+ + ++P+VV+ + + +R LL +EQ + ++ V T++ P ++ D+
Sbjct: 346 YQQKIIPVVVKMFSSTDRAMR----IRLLQQMEQFIQYLDEPTVNTQIFPHVVHGFL-DT 400
Query: 186 NDDVKTEAVAIMCKMAPMVGKDITERLILPRFCEMCCDCRMFHVRKVCAANFGDICSVVG 245
N ++ + V M +AP + + ++ F + +R G I S +
Sbjct: 401 NPAIREQTVKSMLLLAPKLNEANLNVELMKHFARLQAKDEQGPIRCNTTVCLGKIGSYLS 460
Query: 246 QQATEEMLLPRFFQLCSDNVWGVRKACAECFMAVSCATCQEIRRTKLSALFINLISDPSR 305
+L F + D R A F A K+ + L DP +
Sbjct: 461 ASTRHRVLTSAFSRATRDPFAPSRVAGVLGFAATHNLYSMNDCAQKILPVLCGLTVDPEK 520
Query: 306 WVRQAAFQSLGPFISTFANPSSSGQYFKEESK 337
VR AF+++ F+S + S +E K
Sbjct: 521 SVRDQAFKAIRSFLSKLESVSEDPTQLEEVEK 552
>gi|154813197 talpid3 protein [Homo sapiens]
Length = 1472
Score = 37.0 bits (84), Expect = 0.087
Identities = 43/189 (22%), Positives = 74/189 (39%), Gaps = 12/189 (6%)
Query: 452 LYNSFHFWRTPLPEIDLDIELEQNSGGKPSPEGPEEESEGPVPSSPNITMATRKELEEMI 511
LYN+F + PL E++ D ++ K E P PVP S + ++ R+ L E
Sbjct: 312 LYNTFASKQAPLKEVE-DTSFDKQ---KSPLETPAPRRFAPVPVSRDDELSKRENLLEEK 367
Query: 512 ENLEPHIDDPDVKAQVEVLSAALRASSLDAHEETISIEKRSDLQDELDINELPNCKINQE 571
EN+E +V+ ++L+ + T S+ + N P+C+ +
Sbjct: 368 ENMEVSCHRGNVRLLEQILNNNDSLTRKSESSNTTSLTRSKIGWTPEKTNRFPSCEELET 427
Query: 572 DSVPLISDAVENMDSTLHYIHSDSDLSNNSSFSPDEERRTKVQDVVPQALLDQYLSMTDP 631
V ++ D LH + + NS P E +PQ + L T+
Sbjct: 428 TKV-----TMQKSDDVLHDL-GQKEKETNSMVQPKESLSMLKLPDLPQNSVK--LQTTNT 479
Query: 632 SRAQTVDTE 640
+R+ D E
Sbjct: 480 TRSVLKDAE 488
>gi|56549645 nucleoporin 98kD isoform 4 [Homo sapiens]
Length = 1726
Score = 36.2 bits (82), Expect = 0.15
Identities = 32/106 (30%), Positives = 45/106 (42%), Gaps = 13/106 (12%)
Query: 462 PLPEIDLDIELEQNSGGKPSP----EGPEEESEGPVP--SSPNITMATRKELEEMIENLE 515
PLP L+ GKP+P + PE E G V S + + L+ M+E
Sbjct: 891 PLPPASQTTPLQMALNGKPAPPPQSQSPEVEQLGRVVELDSDMVDITQEPVLDTMLEESM 950
Query: 516 PHIDDPDVKAQVEVLSAALRASSLDAHEETISIEKRSDLQDELDIN 561
P +P V A + ASSL + + I K S L DE D++
Sbjct: 951 PEDQEP-VSASTHI------ASSLGINPHVLQIMKASLLTDEEDVD 989
>gi|21264365 nucleoporin 98kD isoform 1 [Homo sapiens]
Length = 1800
Score = 36.2 bits (82), Expect = 0.15
Identities = 32/106 (30%), Positives = 45/106 (42%), Gaps = 13/106 (12%)
Query: 462 PLPEIDLDIELEQNSGGKPSP----EGPEEESEGPVP--SSPNITMATRKELEEMIENLE 515
PLP L+ GKP+P + PE E G V S + + L+ M+E
Sbjct: 891 PLPPASQTTPLQMALNGKPAPPPQSQSPEVEQLGRVVELDSDMVDITQEPVLDTMLEESM 950
Query: 516 PHIDDPDVKAQVEVLSAALRASSLDAHEETISIEKRSDLQDELDIN 561
P +P V A + ASSL + + I K S L DE D++
Sbjct: 951 PEDQEP-VSASTHI------ASSLGINPHVLQIMKASLLTDEEDVD 989
>gi|7661532 nin one binding protein [Homo sapiens]
Length = 412
Score = 36.2 bits (82), Expect = 0.15
Identities = 21/57 (36%), Positives = 29/57 (50%), Gaps = 1/57 (1%)
Query: 435 RPEVGTTSQDSALLDQEL-YNSFHFWRTPLPEIDLDIELEQNSGGKPSPEGPEEESE 490
+P T SA + L ++SF FWR PLP ID +++ G+ P EEE E
Sbjct: 135 KPPQETEKGHSACEPENLEFSSFMFWRNPLPNIDHELQELLIDRGEDVPSEEEEEEE 191
>gi|22748757 truncated type I keratin KA21 [Homo sapiens]
Length = 295
Score = 35.8 bits (81), Expect = 0.19
Identities = 28/82 (34%), Positives = 39/82 (47%), Gaps = 7/82 (8%)
Query: 658 RQNWHCLRETYETLASDMQWKVRRTLAFSIHELAVILGDQLTAADLVPIFNGFLKDLDEV 717
R+ WH L+ E+L + V R L S+H A Q+ DL + G K+L EV
Sbjct: 59 RRQWHHLQVEIESLHA-----VERGLENSLH--ASEQHYQMQLQDLETVIEGLEKELQEV 111
Query: 718 RIGVLKHLHDFLKLLHIDKRRE 739
R G+ K L + LL+ R E
Sbjct: 112 RRGIEKQLQEHEMLLNTKMRLE 133
>gi|148747864 JAW1-related protein isoform a [Homo sapiens]
Length = 903
Score = 35.4 bits (80), Expect = 0.25
Identities = 29/116 (25%), Positives = 48/116 (41%), Gaps = 2/116 (1%)
Query: 463 LPEIDLDIELEQNSGGKPSPEGPEEESEGPVPSSPNIT--MATRKELEEMIENLEPHIDD 520
LP++ E E+ + SP EEES+ + PNI+ + + + + P + +
Sbjct: 462 LPDLSEAAEQEKGLPSELSPAIEEEESKSGLDVMPNISDVLLRKLRVHRSLPGSAPPLTE 521
Query: 521 PDVKAQVEVLSAALRASSLDAHEETISIEKRSDLQDELDINELPNCKINQEDSVPL 576
+V+ LS A R S E+ +L +E EL N K + S L
Sbjct: 522 KEVENVFVQLSLAFRNDSYTLESRINQAERERNLTEENTEKELENFKASITSSASL 577
>gi|154091334 JAW1-related protein isoform c [Homo sapiens]
Length = 597
Score = 35.4 bits (80), Expect = 0.25
Identities = 29/116 (25%), Positives = 48/116 (41%), Gaps = 2/116 (1%)
Query: 463 LPEIDLDIELEQNSGGKPSPEGPEEESEGPVPSSPNIT--MATRKELEEMIENLEPHIDD 520
LP++ E E+ + SP EEES+ + PNI+ + + + + P + +
Sbjct: 156 LPDLSEAAEQEKGLPSELSPAIEEEESKSGLDVMPNISDVLLRKLRVHRSLPGSAPPLTE 215
Query: 521 PDVKAQVEVLSAALRASSLDAHEETISIEKRSDLQDELDINELPNCKINQEDSVPL 576
+V+ LS A R S E+ +L +E EL N K + S L
Sbjct: 216 KEVENVFVQLSLAFRNDSYTLESRINQAERERNLTEENTEKELENFKASITSSASL 271
>gi|154091332 JAW1-related protein isoform b [Homo sapiens]
Length = 821
Score = 35.4 bits (80), Expect = 0.25
Identities = 29/116 (25%), Positives = 48/116 (41%), Gaps = 2/116 (1%)
Query: 463 LPEIDLDIELEQNSGGKPSPEGPEEESEGPVPSSPNIT--MATRKELEEMIENLEPHIDD 520
LP++ E E+ + SP EEES+ + PNI+ + + + + P + +
Sbjct: 380 LPDLSEAAEQEKGLPSELSPAIEEEESKSGLDVMPNISDVLLRKLRVHRSLPGSAPPLTE 439
Query: 521 PDVKAQVEVLSAALRASSLDAHEETISIEKRSDLQDELDINELPNCKINQEDSVPL 576
+V+ LS A R S E+ +L +E EL N K + S L
Sbjct: 440 KEVENVFVQLSLAFRNDSYTLESRINQAERERNLTEENTEKELENFKASITSSASL 495
>gi|148728182 JAW1-related protein isoform b [Homo sapiens]
Length = 821
Score = 35.4 bits (80), Expect = 0.25
Identities = 29/116 (25%), Positives = 48/116 (41%), Gaps = 2/116 (1%)
Query: 463 LPEIDLDIELEQNSGGKPSPEGPEEESEGPVPSSPNIT--MATRKELEEMIENLEPHIDD 520
LP++ E E+ + SP EEES+ + PNI+ + + + + P + +
Sbjct: 380 LPDLSEAAEQEKGLPSELSPAIEEEESKSGLDVMPNISDVLLRKLRVHRSLPGSAPPLTE 439
Query: 521 PDVKAQVEVLSAALRASSLDAHEETISIEKRSDLQDELDINELPNCKINQEDSVPL 576
+V+ LS A R S E+ +L +E EL N K + S L
Sbjct: 440 KEVENVFVQLSLAFRNDSYTLESRINQAERERNLTEENTEKELENFKASITSSASL 495
>gi|117414137 retinitis pigmentosa 1-like 1 [Homo sapiens]
Length = 2400
Score = 35.0 bits (79), Expect = 0.33
Identities = 53/271 (19%), Positives = 96/271 (35%), Gaps = 33/271 (12%)
Query: 323 ANPSSSGQYFKEESKSSEEMSVENKNRTRDQEAPEDVQVRPEDTPSDLSVSNSSVILENT 382
A P S G E ++E E + + D EAPE E P V E
Sbjct: 1844 AQPESEGVEAPEAEGDAQEAEGEAQPESEDVEAPE---AEGEAQPESEDVETPEAEWEVQ 1900
Query: 383 MEDHAAEASGKPLGEISVPLDSSLLCTLSSESHQEAASNENDKKPGNYKSMLRPEVGTTS 442
E AEA P E ++ + L +E E S + + ++ E T
Sbjct: 1901 PESEGAEA---PEAEKEAQPETESVEALETEGEDEPESEGAEAQEAE-EAAQEAEGQTQP 1956
Query: 443 QDSALLDQELYNSFHFWRTPLPEIDLDIELEQNSG---------GKPSPEGPEEESEGPV 493
+ + QE + +++++E ++ G P EG +E+E
Sbjct: 1957 ESEVIESQEAEEEAQPESEDVEALEVEVETQEAEGEAQPESEDVEAPEAEGEMQEAEEEA 2016
Query: 494 -PSSPNITMATRKELEEMIE----------NLEPH---IDDPDVKAQVEVLSAALRASSL 539
P S + + E EE E + +P ++ P+ + + + ++ +
Sbjct: 2017 QPESDGVEAQPKSEGEEAQEVEGETQKTEGDAQPESDGVEAPEAEEEAQEAEGEVQEAEG 2076
Query: 540 DAHEETISI---EKRSDLQDELDINELPNCK 567
+AH E+ + E + Q E + E P +
Sbjct: 2077 EAHPESEDVDAQEAEGEAQPESEGVEAPEAE 2107
>gi|21361639 DIPB protein [Homo sapiens]
Length = 344
Score = 34.7 bits (78), Expect = 0.43
Identities = 18/64 (28%), Positives = 31/64 (48%)
Query: 334 EESKSSEEMSVENKNRTRDQEAPEDVQVRPEDTPSDLSVSNSSVILENTMEDHAAEASGK 393
EES+S EE E ++ T ++ E + ED+ ++ S E+ E+ +EA G+
Sbjct: 97 EESESEEESESEEESETEEESEDESDEESEEDSEEEMEDEQESEAEEDNQEEGESEAEGE 156
Query: 394 PLGE 397
E
Sbjct: 157 TEAE 160
>gi|55770895 ERBB2 interacting protein isoform 7 [Homo sapiens]
Length = 1302
Score = 34.7 bits (78), Expect = 0.43
Identities = 24/77 (31%), Positives = 40/77 (51%), Gaps = 7/77 (9%)
Query: 547 SIEKRSDLQDELDINELPNCKINQEDSVPLISDAVENM---DSTLHYIHSDSDLSN---N 600
S E++ D+ D N LP +N E+ + LI +V++ D T H + +L+ N
Sbjct: 715 STEEKFKAHDKKDFN-LPEYDLNVEERLVLIEKSVDSTATADDTHKLDHINMNLNKLITN 773
Query: 601 SSFSPDEERRTKVQDVV 617
+F P+ R+K QD+V
Sbjct: 774 DTFQPEIMERSKTQDIV 790
>gi|8923909 ERBB2 interacting protein isoform 2 [Homo sapiens]
Length = 1371
Score = 34.7 bits (78), Expect = 0.43
Identities = 24/77 (31%), Positives = 40/77 (51%), Gaps = 7/77 (9%)
Query: 547 SIEKRSDLQDELDINELPNCKINQEDSVPLISDAVENM---DSTLHYIHSDSDLSN---N 600
S E++ D+ D N LP +N E+ + LI +V++ D T H + +L+ N
Sbjct: 715 STEEKFKAHDKKDFN-LPEYDLNVEERLVLIEKSVDSTATADDTHKLDHINMNLNKLITN 773
Query: 601 SSFSPDEERRTKVQDVV 617
+F P+ R+K QD+V
Sbjct: 774 DTFQPEIMERSKTQDIV 790
>gi|188497648 ubiquitin specific peptidase 37 [Homo sapiens]
Length = 979
Score = 34.7 bits (78), Expect = 0.43
Identities = 85/410 (20%), Positives = 157/410 (38%), Gaps = 83/410 (20%)
Query: 250 EEMLLPRFFQL---CSDNVWGVRKACAECFMAVSCATCQEIRRTKLSALFINLISDPSRW 306
+++++PR+ L C++N MA+S R K S + + I+ PS
Sbjct: 580 QQVIIPRYLTLSSHCTENTKPPFTLGWSAHMAIS-------RPLKASQMVNSCITSPSTP 632
Query: 307 VRQAAFQSLGPFISTFANPSSSGQYFKEESKSSEEMSVENKNRTRDQEAPEDVQVRPEDT 366
++ F+S + S ++E K S +S +++ ED++ +
Sbjct: 633 SKKFTFKSKSSLALCLDSDS------EDELKRSVALSQRLCEMLGNEQQQEDLEKDSKLC 686
Query: 367 PSDLSVSNSSVILENTMEDHAAEASGKPLGEISVPLDSSLLCTLSSESHQEAA---SNEN 423
P + S LEN+ D +E LL + S ++A+ S+E+
Sbjct: 687 PIEPDKSE----LENSGFDRMSE--------------EELLAAVLEISKRDASPSLSHED 728
Query: 424 DKKPGNYKSMLRPEVGTTSQDSALLDQELYNSFHFWRTPLPEIDLDIE----------LE 473
D KP + P+ G D QE+ + T P+ +++ +
Sbjct: 729 DDKPTS-----SPDTGFAEDDI----QEMPENPDTMETEKPKTITELDPASFTEITKDCD 779
Query: 474 QNSGGKPSPEGPEEESEGPVPSSPNITMATRKELEEMIENLEPHI---------DDPDVK 524
+N K +PEG S+G V M +E +E+ + L + +D D+K
Sbjct: 780 ENKENK-TPEG----SQGEVDWLQQYDMEREREEQELQQALAQSLQEQEAWEQKEDDDLK 834
Query: 525 AQVEVLSAALRASSLDA--------HEETISIEKRSDLQDELDINELPNCKINQEDSVPL 576
E+ S +DA +E+ +E +EL N N S L
Sbjct: 835 RATELSLQEFNNSFVDALGSDEDSGNEDVFDMEYTEAEAEELKRNAETG---NLPHSYRL 891
Query: 577 IS--DAVENMDSTLHYIHSDSDLSNNSSFSPDEERRTKVQDVVPQALLDQ 624
IS + + S+ HYI D+ + F+ ++ +K+Q+ Q+ D+
Sbjct: 892 ISVVSHIGSTSSSGHYISDVYDIKKQAWFTYNDLEVSKIQEAAVQSDRDR 941
>gi|34577059 adipose differentiation-related protein [Homo sapiens]
Length = 437
Score = 34.3 bits (77), Expect = 0.57
Identities = 41/189 (21%), Positives = 77/189 (40%), Gaps = 24/189 (12%)
Query: 571 EDSVPLISDAVENMDSTLHYIHSDSDL---SNNSSFSPDEERRTKVQDVVPQALLDQYLS 627
+ ++ + +A + T+ +HS L + + +S ++ K+QD + YLS
Sbjct: 233 QQALSRVKEAKQKSQQTISQLHSTVHLIEFARKNVYSANQ----KIQDAQDKL----YLS 284
Query: 628 MTDPSRAQTVDTEIAKHCAYSLPGVALTLGRQNWHCLRETYETLASDMQWKVRRTLAFSI 687
+ R+ D HCA + L + R L+ T TL S++Q + +I
Sbjct: 285 WVEWKRSIGYDDTDESHCAEHIESRTLAIARNLTQQLQTTCHTLLSNIQ-----GVPQNI 339
Query: 688 HELAVILGDQLTAADLVPIFNGFLKDLDEVRIGVLKHLHDFLKLLHIDKRREYLYQLQEF 747
+ A +G + A D+ +F EV +L + K +E L + ++
Sbjct: 340 QDQAKHMG--VMAGDIYSVFRN-AASFKEVSDSLLTSSKG-----QLQKMKESLDDVMDY 391
Query: 748 LVTDNSRNW 756
LV + NW
Sbjct: 392 LVNNTPLNW 400
>gi|23943912 phosphoinositide-3-kinase, regulatory subunit 4 [Homo
sapiens]
Length = 1358
Score = 34.3 bits (77), Expect = 0.57
Identities = 42/208 (20%), Positives = 88/208 (42%), Gaps = 30/208 (14%)
Query: 87 VLERIS----RLADDSEPTVRAELMEQVPHIALFCQENRPSIPYAFSKFLLPIVVRYLAD 142
+L+RI+ ++DS P VRAE + + + +E + + +++LP + +LA
Sbjct: 414 LLDRITPYLLHFSNDSVPRVRAEALRTLTKVLALVKEVPRNDINIYPEYILP-GIAHLAQ 472
Query: 143 QNNQVRKTSQAALLALLEQ------ELIERFDVETKVCP---VLIELTAPDSNDDVKTEA 193
+ + + + A +ALL + EL++ ++ + P + E+T P+ N D + +A
Sbjct: 473 DDATIVRLAYAENIALLAETALRFLELVQLKNLNMENDPNNEEIDEVTHPNGNYDTELQA 532
Query: 194 VAIMCKMAPMVGKDITERLILPRFCEMCCDCRMFHVRKVCAANFGDICSVVGQQATEEML 253
+ M + + E ++ E +C G+Q ++L
Sbjct: 533 LHEMVQQKVVTLLSDPENIVKQTLME---------------NGITRLCVFFGRQKANDVL 577
Query: 254 LPRFFQLCSD-NVWGVRKACAECFMAVS 280
L +D N W +R A + + V+
Sbjct: 578 LSHMITFLNDKNDWHLRGAFFDSIVGVA 605
>gi|5174573 myeloid/lymphoid or mixed-lineage leukemia trithorax
homolog 2 [Homo sapiens]
Length = 1210
Score = 34.3 bits (77), Expect = 0.57
Identities = 63/304 (20%), Positives = 115/304 (37%), Gaps = 37/304 (12%)
Query: 336 SKSSEEMSVENKNRTRDQEAPEDVQVRPEDTPSDL----SVSNSSVILENTMEDHAAEAS 391
+KS ++++V + D+E P+D V P PS S+ + SV ++ A
Sbjct: 243 AKSPKDLAV----KVHDKETPQDSLVAPAQPPSQTFPPPSLPSKSVAMQ-----QKPTAY 293
Query: 392 GKPL-GEISVPLDSSLLCTLSSESHQEAASNENDKKPGNYK--SMLRPEVG---TTSQDS 445
+P+ G+ P +S L L + Q+ + K P K + P T S +
Sbjct: 294 VRPMDGQDQAPSESPELKPLPEDYRQQTFEKTDLKVPAKAKLTKLKMPSQSVEQTYSNEV 353
Query: 446 ALLDQELYNSFHFWRTPLPEIDLDIELEQNSGGKPSPEGP--------EEESEGPVPSSP 497
+++ L H W PL I E + P+ + +++ + +
Sbjct: 354 HCVEEILKEMTHSWPPPLTAIHTPSTAEPSKFPFPTKDSQHVSSVTQNQKQYDTSSKTHS 413
Query: 498 NITMATRKELEEMIENLEPHIDDPDVKAQVEVLSAA-------LRASSLDAHEETISIEK 550
N T LE+ ++ + D + + S+A L AH + E
Sbjct: 414 NSQQGTSSMLEDDLQLSDSEDSDSEQTPEKPPSSSAPPSAPQSLPEPVASAHSSSAESES 473
Query: 551 RSDLQDELDINELPNCKINQEDSVPLISDAVENMDSTLHYIHSDSDLSNNS--SFSPDEE 608
SD D +E + + E++ PL + A E T + D+ L+ S + P+
Sbjct: 474 TSDSDSSSD-SESESSSSDSEENEPLETPAPEPEPPTTNKWQLDNWLTKVSQPAAPPEGP 532
Query: 609 RRTK 612
R T+
Sbjct: 533 RSTE 536
>gi|55770902 opioid growth factor receptor-like 1 [Homo sapiens]
Length = 451
Score = 34.3 bits (77), Expect = 0.57
Identities = 29/115 (25%), Positives = 57/115 (49%), Gaps = 6/115 (5%)
Query: 317 PFISTFANPSSSGQYFKEESKSSEEMSVENKNRTRDQEAPEDVQVRPEDTPSDLSVSNSS 376
P S+ + +S + K+ SS + + +K + AP++ V D PS SN +
Sbjct: 331 PLASSHNSQTSMHKKAKDSKNSSSAVHLNSKTAEDKKVAPKE-PVEETDRPSP-EPSNEA 388
Query: 377 VILENTMEDHAAE-ASGKPLGEISVPLDSSLLCTLSSESHQEAAS-NENDKKPGN 429
NT +D AE + +P ++ P + ++S E+++E + N++++ PGN
Sbjct: 389 AKPRNTEKDSNAENMNSQPEKTVTTPTEKKE--SVSPENNEEGGNDNQDNENPGN 441
>gi|34577118 dopey family member 1 [Homo sapiens]
Length = 2465
Score = 34.3 bits (77), Expect = 0.57
Identities = 39/157 (24%), Positives = 69/157 (43%), Gaps = 23/157 (14%)
Query: 480 PSPEGPEEESEGPVPSSPN--ITMATRKELEEMIENLEPHIDDPDVKAQVEVLSAALRAS 537
P +E+S+ P SSP+ + + +++ LE ++ V +Q+E+ + + S
Sbjct: 1128 PETVNAQEDSQMPKESSPDDDVQQVVFDLICKVVSGLE--VESASVTSQLEIEAMPPKCS 1185
Query: 538 SLDAHEETISIEKRSDLQDELDI----------------NELPNCKINQEDSVPLISDAV 581
+D EETI IE S Q + + +E I++ S P IS
Sbjct: 1186 DIDPDEETIKIEDDSIQQSQNALLSNESSQFLSVSAEGGHECVANGISRNSSSPCISGTT 1245
Query: 582 ENM-DSTLHYIHSDSDLSNNSS--FSPDEERRTKVQD 615
+ DS++ I + S ++SS FS E+ KV +
Sbjct: 1246 HTLHDSSVASIETKSRQRSHSSIQFSFKEKLSEKVSE 1282
>gi|5031703 Ras-GTPase-activating protein SH3-domain-binding protein
[Homo sapiens]
Length = 466
Score = 34.3 bits (77), Expect = 0.57
Identities = 30/121 (24%), Positives = 41/121 (33%), Gaps = 22/121 (18%)
Query: 329 GQYFKEESKSSEEMSVENKNRTRDQEAPEDVQVRPEDTPSDLSVSNSSVILENTMEDHAA 388
G + E + SEE + E PE+ Q PE P D ++ N ME+H
Sbjct: 139 GGFVTEPQEESEE----------EVEEPEERQQTPEVVPDDSGTFYDQAVVSNDMEEHLE 188
Query: 389 EASGKPLGEISVPLDSSLLCTLSSESHQEAASNENDKKPGNYKSMLRPEVGTTSQDSALL 448
E +P + E QE S ++KP PE S A
Sbjct: 189 EPVAEPEPD------------PEPEPEQEPVSEIQEEKPEPVLEETAPEDAQKSSSPAPA 236
Query: 449 D 449
D
Sbjct: 237 D 237
>gi|38327552 Ras-GTPase-activating protein SH3-domain-binding
protein [Homo sapiens]
Length = 466
Score = 34.3 bits (77), Expect = 0.57
Identities = 30/121 (24%), Positives = 41/121 (33%), Gaps = 22/121 (18%)
Query: 329 GQYFKEESKSSEEMSVENKNRTRDQEAPEDVQVRPEDTPSDLSVSNSSVILENTMEDHAA 388
G + E + SEE + E PE+ Q PE P D ++ N ME+H
Sbjct: 139 GGFVTEPQEESEE----------EVEEPEERQQTPEVVPDDSGTFYDQAVVSNDMEEHLE 188
Query: 389 EASGKPLGEISVPLDSSLLCTLSSESHQEAASNENDKKPGNYKSMLRPEVGTTSQDSALL 448
E +P + E QE S ++KP PE S A
Sbjct: 189 EPVAEPEPD------------PEPEPEQEPVSEIQEEKPEPVLEETAPEDAQKSSSPAPA 236
Query: 449 D 449
D
Sbjct: 237 D 237
Database: hs.faa
Posted date: Aug 4, 2009 4:42 PM
Number of letters in database: 18,247,518
Number of sequences in database: 37,866
Lambda K H
0.317 0.132 0.382
Gapped
Lambda K H
0.267 0.0410 0.140
Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Hits to DB: 34,860,255
Number of Sequences: 37866
Number of extensions: 1597634
Number of successful extensions: 6597
Number of sequences better than 10.0: 30
Number of HSP's better than 10.0 without gapping: 18
Number of HSP's successfully gapped in prelim test: 114
Number of HSP's that attempted gapping in prelim test: 6317
Number of HSP's gapped (non-prelim): 315
length of query: 950
length of database: 18,247,518
effective HSP length: 112
effective length of query: 838
effective length of database: 14,006,526
effective search space: 11737468788
effective search space used: 11737468788
T: 11
A: 40
X1: 16 ( 7.3 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 41 (21.7 bits)
S2: 67 (30.4 bits)
Search results were obtained with NCBI BLAST and RefSeq entries.
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Guide to the Human Genome
Copyright © 2010 by Stewart Scherer. All rights reserved.