Guide to the Human Genome
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Search of human proteins with 108773787

BLASTP 2.2.11 [Jun-05-2005]


Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer, 
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), 
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs",  Nucleic Acids Res. 25:3389-3402.

Query= gi|108773787 retinoblastoma 1 [Homo sapiens]
         (928 letters)

Database: hs.faa 
           37,866 sequences; 18,247,518 total letters

Searching..................................................done

                                                                 Score    E
Sequences producing significant alignments:                      (bits) Value

gi|108773787 retinoblastoma 1 [Homo sapiens]                         1852   0.0  
gi|172072597 retinoblastoma-like 2 (p130) [Homo sapiens]              194   2e-49
gi|34577079 retinoblastoma-like protein 1 isoform a [Homo sapiens]    181   3e-45
gi|34577077 retinoblastoma-like protein 1 isoform b [Homo sapiens]    181   3e-45
gi|55956904 mitogen-activated protein kinase kinase kinase 4 iso...    49   3e-05
gi|55956902 mitogen-activated protein kinase kinase kinase 4 iso...    49   3e-05
gi|110347459 MYC-associated zinc finger protein isoform 2 [Homo ...    42   0.003
gi|110347461 MYC-associated zinc finger protein isoform 1 [Homo ...    42   0.003
gi|17986273 fast skeletal myosin alkali light chain 1 isoform 1f...    42   0.003
gi|56118221 amyloid beta (A4) precursor protein-binding, family ...    41   0.006
gi|25777598 diacylglycerol kinase, delta 130kDa isoform 2 [Homo ...    40   0.010
gi|39930517 sterile alpha motif domain containing 1 [Homo sapiens]     40   0.010
gi|61743948 abl-interactor 1 isoform d [Homo sapiens]                  40   0.013
gi|61743944 abl-interactor 1 isoform b [Homo sapiens]                  40   0.013
gi|61743942 abl-interactor 1 isoform a [Homo sapiens]                  40   0.013
gi|4507909 Wiskott-Aldrich syndrome protein [Homo sapiens]             39   0.017
gi|122937496 WAS/WASL interacting protein family, member 3 [Homo...    39   0.017
gi|33188449 serine/arginine-rich protein-specific kinase 2 isofo...    39   0.022
gi|61743946 abl-interactor 1 isoform c [Homo sapiens]                  39   0.022
gi|126090663 zinc finger homeodomain 4 [Homo sapiens]                  39   0.022
gi|117938310 sine oculis binding protein homolog [Homo sapiens]        39   0.022
gi|46048439 N-acetyltransferase 6 [Homo sapiens]                       39   0.029
gi|148229134 ring finger and KH domain containing 2 [Homo sapiens]     39   0.029
gi|195947369 junction-mediating and regulatory protein [Homo sap...    38   0.038
gi|156523246 proline-rich transmembrane protein 2 [Homo sapiens]       38   0.038
gi|164698460 mannosidase, endo-alpha-like isoform 3 [Homo sapiens]     38   0.038
gi|72534766 mannosidase, endo-alpha-like isoform 1 [Homo sapiens]      38   0.038
gi|158534059 formin binding protein 4 [Homo sapiens]                   38   0.050
gi|149944526 additional sex combs like 3 [Homo sapiens]                38   0.050
gi|5730045 solute carrier family 16, member 2 [Homo sapiens]           37   0.065

>gi|108773787 retinoblastoma 1 [Homo sapiens]
          Length = 928

 Score = 1852 bits (4797), Expect = 0.0
 Identities = 928/928 (100%), Positives = 928/928 (100%)

Query: 1   MPPKTPRKTAATAAAAAAEPPAPPPPPPPEEDPEQDSGPEDLPLVRLEFEETEEPDFTAL 60
           MPPKTPRKTAATAAAAAAEPPAPPPPPPPEEDPEQDSGPEDLPLVRLEFEETEEPDFTAL
Sbjct: 1   MPPKTPRKTAATAAAAAAEPPAPPPPPPPEEDPEQDSGPEDLPLVRLEFEETEEPDFTAL 60

Query: 61  CQKLKIPDHVRERAWLTWEKVSSVDGVLGGYIQKKKELWGICIFIAAVDLDEMSFTFTEL 120
           CQKLKIPDHVRERAWLTWEKVSSVDGVLGGYIQKKKELWGICIFIAAVDLDEMSFTFTEL
Sbjct: 61  CQKLKIPDHVRERAWLTWEKVSSVDGVLGGYIQKKKELWGICIFIAAVDLDEMSFTFTEL 120

Query: 121 QKNIEISVHKFFNLLKEIDTSTKVDNAMSRLLKKYDVLFALFSKLERTCELIYLTQPSSS 180
           QKNIEISVHKFFNLLKEIDTSTKVDNAMSRLLKKYDVLFALFSKLERTCELIYLTQPSSS
Sbjct: 121 QKNIEISVHKFFNLLKEIDTSTKVDNAMSRLLKKYDVLFALFSKLERTCELIYLTQPSSS 180

Query: 181 ISTEINSALVLKVSWITFLLAKGEVLQMEDDLVISFQLMLCVLDYFIKLSPPMLLKEPYK 240
           ISTEINSALVLKVSWITFLLAKGEVLQMEDDLVISFQLMLCVLDYFIKLSPPMLLKEPYK
Sbjct: 181 ISTEINSALVLKVSWITFLLAKGEVLQMEDDLVISFQLMLCVLDYFIKLSPPMLLKEPYK 240

Query: 241 TAVIPINGSPRTPRRGQNRSARIAKQLENDTRIIEVLCKEHECNIDEVKNVYFKNFIPFM 300
           TAVIPINGSPRTPRRGQNRSARIAKQLENDTRIIEVLCKEHECNIDEVKNVYFKNFIPFM
Sbjct: 241 TAVIPINGSPRTPRRGQNRSARIAKQLENDTRIIEVLCKEHECNIDEVKNVYFKNFIPFM 300

Query: 301 NSLGLVTSNGLPEVENLSKRYEEIYLKNKDLDARLFLDHDKTLQTDSIDSFETQRTPRKS 360
           NSLGLVTSNGLPEVENLSKRYEEIYLKNKDLDARLFLDHDKTLQTDSIDSFETQRTPRKS
Sbjct: 301 NSLGLVTSNGLPEVENLSKRYEEIYLKNKDLDARLFLDHDKTLQTDSIDSFETQRTPRKS 360

Query: 361 NLDEEVNVIPPHTPVRTVMNTIQQLMMILNSASDQPSENLISYFNNCTVNPKESILKRVK 420
           NLDEEVNVIPPHTPVRTVMNTIQQLMMILNSASDQPSENLISYFNNCTVNPKESILKRVK
Sbjct: 361 NLDEEVNVIPPHTPVRTVMNTIQQLMMILNSASDQPSENLISYFNNCTVNPKESILKRVK 420

Query: 421 DIGYIFKEKFAKAVGQGCVEIGSQRYKLGVRLYYRVMESMLKSEEERLSIQNFSKLLNDN 480
           DIGYIFKEKFAKAVGQGCVEIGSQRYKLGVRLYYRVMESMLKSEEERLSIQNFSKLLNDN
Sbjct: 421 DIGYIFKEKFAKAVGQGCVEIGSQRYKLGVRLYYRVMESMLKSEEERLSIQNFSKLLNDN 480

Query: 481 IFHMSLLACALEVVMATYSRSTSQNLDSGTDLSFPWILNVLNLKAFDFYKVIESFIKAEG 540
           IFHMSLLACALEVVMATYSRSTSQNLDSGTDLSFPWILNVLNLKAFDFYKVIESFIKAEG
Sbjct: 481 IFHMSLLACALEVVMATYSRSTSQNLDSGTDLSFPWILNVLNLKAFDFYKVIESFIKAEG 540

Query: 541 NLTREMIKHLERCEHRIMESLAWLSDSPLFDLIKQSKDREGPTDHLESACPLNLPLQNNH 600
           NLTREMIKHLERCEHRIMESLAWLSDSPLFDLIKQSKDREGPTDHLESACPLNLPLQNNH
Sbjct: 541 NLTREMIKHLERCEHRIMESLAWLSDSPLFDLIKQSKDREGPTDHLESACPLNLPLQNNH 600

Query: 601 TAADMYLSPVRSPKKKGSTTRVNSTANAETQATSAFQTQKPLKSTSLSLFYKKVYRLAYL 660
           TAADMYLSPVRSPKKKGSTTRVNSTANAETQATSAFQTQKPLKSTSLSLFYKKVYRLAYL
Sbjct: 601 TAADMYLSPVRSPKKKGSTTRVNSTANAETQATSAFQTQKPLKSTSLSLFYKKVYRLAYL 660

Query: 661 RLNTLCERLLSEHPELEHIIWTLFQHTLQNEYELMRDRHLDQIMMCSMYGICKVKNIDLK 720
           RLNTLCERLLSEHPELEHIIWTLFQHTLQNEYELMRDRHLDQIMMCSMYGICKVKNIDLK
Sbjct: 661 RLNTLCERLLSEHPELEHIIWTLFQHTLQNEYELMRDRHLDQIMMCSMYGICKVKNIDLK 720

Query: 721 FKIIVTAYKDLPHAVQETFKRVLIKEEEYDSIIVFYNSVFMQRLKTNILQYASTRPPTLS 780
           FKIIVTAYKDLPHAVQETFKRVLIKEEEYDSIIVFYNSVFMQRLKTNILQYASTRPPTLS
Sbjct: 721 FKIIVTAYKDLPHAVQETFKRVLIKEEEYDSIIVFYNSVFMQRLKTNILQYASTRPPTLS 780

Query: 781 PIPHIPRSPYKFPSSPLRIPGGNIYISPLKSPYKISEGLPTPTKMTPRSRILVSIGESFG 840
           PIPHIPRSPYKFPSSPLRIPGGNIYISPLKSPYKISEGLPTPTKMTPRSRILVSIGESFG
Sbjct: 781 PIPHIPRSPYKFPSSPLRIPGGNIYISPLKSPYKISEGLPTPTKMTPRSRILVSIGESFG 840

Query: 841 TSEKFQKINQMVCNSDRVLKRSAEGSNPPKPLKKLRFDIEGSDEADGSKHLPGESKFQQK 900
           TSEKFQKINQMVCNSDRVLKRSAEGSNPPKPLKKLRFDIEGSDEADGSKHLPGESKFQQK
Sbjct: 841 TSEKFQKINQMVCNSDRVLKRSAEGSNPPKPLKKLRFDIEGSDEADGSKHLPGESKFQQK 900

Query: 901 LAEMTSTRTRMQKQKMNDSMDTSNKEEK 928
           LAEMTSTRTRMQKQKMNDSMDTSNKEEK
Sbjct: 901 LAEMTSTRTRMQKQKMNDSMDTSNKEEK 928


>gi|172072597 retinoblastoma-like 2 (p130) [Homo sapiens]
          Length = 1139

 Score =  194 bits (494), Expect = 2e-49
 Identities = 176/700 (25%), Positives = 298/700 (42%), Gaps = 98/700 (14%)

Query: 23  PPPPPPP-----EEDPEQDSGPEDLPLVRLEFEETEEPDFTALCQKLKIPDHVRERAWLT 77
           PPPPPPP     +E+ E D   ED            +  F  LC +L + +  R  AW +
Sbjct: 10  PPPPPPPAAAASDEEEEDDGEAEDAAPPAESPTPQIQQRFDELCSRLNMDEAARAEAWDS 69

Query: 78  WEKVSSVDGVLGGYIQKKKELWGICIFIAAV----------DLDEMSFTFTELQKNIEIS 127
           +  +S    + G  +      W  C    A            ++    + T + K  E S
Sbjct: 70  YRSMSESYTLEGNDLH-----WLACALYVACRKSVPTVSKGTVEGNYVSLTRILKCSEQS 124

Query: 128 VHKFFNLLKEIDTSTKVD----NAMSRLLKKYDVLFALFSKLERTCELIYL----TQPSS 179
           + +FFN +K+ +    +         RL + + V   +F K E   + I+      QP  
Sbjct: 125 LIEFFNKMKKWEDMANLPPHFRERTERLERNFTVSAVIFKKYEPIFQDIFKYPQEEQPRQ 184

Query: 180 SISTE-----INSALVLKVSWITFLLAKGEVLQMEDDLVISFQLMLCVLDYFIKLSPPML 234
               +        + +    W+ F+ AKG    + DDLV S+ L+LC LD    L     
Sbjct: 185 QRGRKQRRQPCTVSEIFHFCWVLFIYAKGNFPMISDDLVNSYHLLLCALD----LVYGNA 240

Query: 235 LKEPYKTAVIPINGSPRTPRRGQNRSARIAKQLENDTRIIEVLCKEHECNIDEVKNVYFK 294
           L+   +  ++    +P      ++  A+ +K   +   IIE LC  H+  + E K +   
Sbjct: 241 LQCSNRKELV----NPNFKGLSEDFHAKDSKPSSDPPCIIEKLCSLHDGLVLEAKGIKEH 296

Query: 295 NFIPFMNSL--------------GLVTSNGLPE-VENLSKRYEEIYLKNKDLDARLFLDH 339
            + P++  L              G +      E  + ++K YEE  L   +LD R+FL  
Sbjct: 297 FWKPYIRKLYEKKLLKGKEENLTGFLEPGNFGESFKAINKAYEEYVLSVGNLDERIFLGE 356

Query: 340 DKTLQTDSI-----------------------DSFETQRTPRKSNLDEEVNVI----PPH 372
           D   +  ++                         F+  +  R S     V  I    P  
Sbjct: 357 DAEEEIGTLSRCLNAGSGTETAERVQMKNILQQHFDKSKALRISTPLTGVRYIKENSPCV 416

Query: 373 TPVRTVMNTIQQLMMILNSASDQPSENLISYFNNCTVNPKESILKRVKDIGYIFKEKFA- 431
           TPV T  +++ +L  +L    + PSE L      C+ +P ++I  R+K++  I+ + F  
Sbjct: 417 TPVSTATHSLSRLHTMLTGLRNAPSEKLEQILRTCSRDPTQAIANRLKEMFEIYSQHFQP 476

Query: 432 -KAVGQGCVEIGSQRYKLGVRLYYRVMESMLKSEEERLSIQNFSKLLNDNIFHMSLLACA 490
            +       EI S+ ++    LYY+V+ES+++ E++RL   + S +L  + FH SLLAC 
Sbjct: 477 DEDFSNCAKEIASKHFRFAEMLYYKVLESVIEQEQKRLGDMDLSGILEQDAFHRSLLACC 536

Query: 491 LEVVMATYSRSTSQNLDSGTDLSFPWILNVLNLKAFDFYKVIESFIKAEGNLTREMIKHL 550
           LEVV  +Y              +FP+I  + ++  + FYKVIE FI+AE  L RE++KHL
Sbjct: 537 LEVVTFSYKPPG----------NFPFITEIFDVPLYHFYKVIEVFIRAEDGLCREVVKHL 586

Query: 551 ERCEHRIMESLAWLSDSPLFDLIKQSKDREGPTDHLESACPLNLPLQNNHTAADMYLSPV 610
            + E +I++ LAW  +SPL++ I+ +++R    +  E   P NL   +    A   L+P 
Sbjct: 587 NQIEEQILDHLAWKPESPLWEKIRDNENRVPTCE--EVMPPQNLERADEICIAGSPLTPR 644

Query: 611 RSPKKKGSTTRVNSTANAETQATSAFQTQKPLKSTSLSLF 650
           R  + +  T  +  +  + T     + +  P  +T   LF
Sbjct: 645 RVTEVRADTGGLGRSITSPTTLYDRY-SSPPASTTRRRLF 683



 Score = 94.0 bits (232), Expect = 6e-19
 Identities = 69/211 (32%), Positives = 106/211 (50%), Gaps = 18/211 (8%)

Query: 596 LQNNHTAADMYLSPVRSPKKKGSTTRVNSTANAETQATSAFQTQKPLKSTSLSLFYKKVY 655
           LQ     A   +SP    +K+G +  V S++N            +P K++SLSLF++KVY
Sbjct: 799 LQVPGQVAIQQISPGGQQQKQGQS--VTSSSN------------RPRKTSSLSLFFRKVY 844

Query: 656 RLAYLRLNTLCERLLSEHPELEHIIWTLFQHTLQNEYELMRDRHLDQIMMCSMYGICKVK 715
            LA +RL  LC +L     EL   IWT F+ ++    ELM DRHLDQ++MC++Y + KV 
Sbjct: 845 HLAAVRLRDLCAKL-DISDELRKKIWTCFEFSIIQCPELMMDRHLDQLLMCAIYVMAKVT 903

Query: 716 NIDLKFKIIVTAYKDLPHAVQETFKRVLIKEEEYDSIIVFYNSVFMQRLKTNILQYASTR 775
             D  F+ I+  Y+  P A  + ++ VLIK +         +S   Q   T + +  ++R
Sbjct: 904 KEDKSFQNIMRCYRTQPQARSQVYRSVLIKGKRKRRNSGSSDSRSHQNSPTELNKDRTSR 963

Query: 776 --PPTLSPIPHIP-RSPYKFPSSPLRIPGGN 803
              P +     +P   P   P +P R+ G N
Sbjct: 964 DSSPVMRSSSTLPVPQPSSAPPTPTRLTGAN 994



 Score = 47.0 bits (110), Expect = 8e-05
 Identities = 38/135 (28%), Positives = 65/135 (48%), Gaps = 27/135 (20%)

Query: 744  IKEEEYDSIIVFYNSVFMQRLKTNILQY--ASTRPPTLSPIPHIPRSPYKFPSSPLRI-- 799
            ++EEE   +I FYN+++++++KT  ++Y  A+   P LSP P +         SP RI  
Sbjct: 997  MEEEERGDLIQFYNNIYIKQIKTFAMKYSQANMDAPPLSPYPFVR------TGSPRRIQL 1050

Query: 800  -PGGNIYISPLKSPYKISEGLPTPTKMTPRSRILVSIGESFGTSEKFQKINQMVCNSDRV 858
                 +YISP K+           T ++PR +I      S   S++ ++IN M+   +  
Sbjct: 1051 SQNHPVYISPHKN----------ETMLSPREKIFYYFSNS--PSKRLREINSMIRTGETP 1098

Query: 859  LKRSA----EGSNPP 869
             K+      +GS  P
Sbjct: 1099 TKKRGILLEDGSESP 1113


>gi|34577079 retinoblastoma-like protein 1 isoform a [Homo sapiens]
          Length = 1068

 Score =  181 bits (459), Expect = 3e-45
 Identities = 157/565 (27%), Positives = 257/565 (45%), Gaps = 91/565 (16%)

Query: 116 TFTELQKNIEISVHKFFNLLKE-IDTST---KVDNAMSRLLKKYDVLFALFSKLERTCEL 171
           + T + ++ ++S+ +FF+ +K+ +D S    +    + RL + ++V   +F K E     
Sbjct: 86  SLTRILRSAKLSLIQFFSKMKKWMDMSNLPQEFRERIERLERNFEVSTVIFKKYEPIFLD 145

Query: 172 IYLTQ-------PSSSISTEINSAL--VLKVSWITFLLAKGEVLQMEDDLVISFQLMLCV 222
           I+          P S     I  ++  +    W  F+  KG    + DDLV S+ L+LC 
Sbjct: 146 IFQNPYEEPPKLPRSRKQRRIPCSVKDLFNFCWTLFVYTKGNFRMIGDDLVNSYHLLLCC 205

Query: 223 LDYFIK---LSPPM--LLKEPYKTAVIPINGSPRTPRRGQNRSARIAKQLENDTRIIEVL 277
           LD       + P    LL   +K      + +  T               E    II VL
Sbjct: 206 LDLIFANAIMCPNRQDLLNPSFKGLPSDFHTADFTAS-------------EEPPCIIAVL 252

Query: 278 CKEHECNIDEVKNV---YFKNFIPFMNSLGLVTSNGLPEVEN-------LSKRYEEIYLK 327
           C+ H+  + E K +   YFK +I  +    ++    L ++ +       ++K YEE  L 
Sbjct: 253 CELHDGLLVEAKGIKEHYFKPYISKLFDRKILKGECLLDLSSFTDNSKAVNKEYEEYVLT 312

Query: 328 NKDLDARLFLDHDKTLQTDSIDSFETQRTPRKSNLDEEVNV---IPPH------------ 372
             D D R+FL  D   +  +   F T+ TP    L  + NV   +  H            
Sbjct: 313 VGDFDERIFLGADAEEEIGTPRKF-TRDTP-LGKLTAQANVEYNLQQHFEKKRSFAPSTP 370

Query: 373 --------------TPVRTVMNTIQQLMMILNSASDQPSENLISYFNNCTVNPKESILKR 418
                         TPV +   ++ +L  I+    + PS+ LI+ F +C  NP E+I+K 
Sbjct: 371 LTGRRYLREKEAVITPVASATQSVSRLQSIVAGLKNAPSDQLINIFESCVRNPVENIMKI 430

Query: 419 VKDIGYIFKEKFAKAVGQ---GCVEIGSQRYKLGVRLYYRVMESMLKSEEERLSIQNFSK 475
           +K IG  F + + ++  +     ++    R KL   LYY+++E+++  E  RL   + S 
Sbjct: 431 LKGIGETFCQHYTQSTDEQPGSHIDFAVNRLKLAEILYYKILETVMVQETRRLHGMDMSV 490

Query: 476 LLNDNIFHMSLLACALEVVMATYSRSTSQNLDSGTDLSFPWILNVLNLKAFDFYKVIESF 535
           LL  +IFH SL+AC LE+V+  YS          +  +FPWI+ VLNL+ F FYKVIE  
Sbjct: 491 LLEQDIFHRSLMACCLEIVLFAYS----------SPRTFPWIIEVLNLQPFYFYKVIEVV 540

Query: 536 IKAEGNLTREMIKHLERCEHRIMESLAWLSDSPLFDLIKQSKDREGPTDHLESACPLNLP 595
           I++E  L+R+M+KHL   E +I+ESLAW  DS L++ ++ S ++    +  E   P N  
Sbjct: 541 IRSEEGLSRDMVKHLNSIEEQILESLAWSHDSALWEALQVSANKVPTCE--EVIFPNNFE 598

Query: 596 LQNNHTAAD----MYLSPVRSPKKK 616
             N          M +SP+  P+ K
Sbjct: 599 TGNGGNVQGHLPLMPMSPLMHPRVK 623



 Score =  117 bits (292), Expect = 6e-26
 Identities = 100/332 (30%), Positives = 151/332 (45%), Gaps = 70/332 (21%)

Query: 594  LPLQNNHTAADMYLSPVRSPKKK---GSTTRVNSTANAETQATSAFQTQKPLKSTSLSLF 650
            +PL  N        SPV          S  + N T   E  +T      +P ++ SL+LF
Sbjct: 735  IPLSMNTNQESKVKSPVSLTAHSLIGASPKQTNLTKAQEVHSTGI---NRPKRTGSLALF 791

Query: 651  YKKVYRLAYLRLNTLCERLLSEHPELEHIIWTLFQHTLQNEYELMRDRHLDQIMMCSMYG 710
            Y+KVY LA +RL  LC +L   + EL   IWT F+ TL +  +LM+DRHLDQ+++C+ Y 
Sbjct: 792  YRKVYHLASVRLRDLCLKLDVSN-ELRRKIWTCFEFTLVHCPDLMKDRHLDQLLLCAFYI 850

Query: 711  ICKVKNIDLKFKIIVTAYKDLPHAVQETFKRVLIK------------------------- 745
            + KV   +  F+ I+ +Y++ P A    ++ VL+K                         
Sbjct: 851  MAKVTKEERTFQEIMKSYRNQPQANSHVYRSVLLKSIPREVVAYNKNINDDFEMIDCDLE 910

Query: 746  -------------EEEYDSIIVFYNSVFMQRLKTNILQYASTR------PPTLSPIPHIP 786
                         +EE   +I FYN++++ R+K+  L+Y           P LSP PHI 
Sbjct: 911  DATKTPDCSSGPVKEERGDLIKFYNTIYVGRVKSFALKYDLANQDHMMDAPPLSPFPHIK 970

Query: 787  RSPYKFPSSPLRI-PGGNIYISPLKSPYKISEGLPTPTKMTPRSRILVSIGESFGTSEKF 845
            +     P SP RI    +IYI    SP+K   GL      TPRS +L     S   S+  
Sbjct: 971  QQ----PGSPRRISQQHSIYI----SPHKNGSGL------TPRSALLYKFNGS--PSKSL 1014

Query: 846  QKINQMVCNSDRVLKRS--AEGSNPPKPLKKL 875
            + IN M+   ++  K+   A  S+   P K++
Sbjct: 1015 KDINNMIRQGEQRTKKRVIAIDSDAESPAKRV 1046


>gi|34577077 retinoblastoma-like protein 1 isoform b [Homo sapiens]
          Length = 1014

 Score =  181 bits (459), Expect = 3e-45
 Identities = 157/565 (27%), Positives = 257/565 (45%), Gaps = 91/565 (16%)

Query: 116 TFTELQKNIEISVHKFFNLLKE-IDTST---KVDNAMSRLLKKYDVLFALFSKLERTCEL 171
           + T + ++ ++S+ +FF+ +K+ +D S    +    + RL + ++V   +F K E     
Sbjct: 86  SLTRILRSAKLSLIQFFSKMKKWMDMSNLPQEFRERIERLERNFEVSTVIFKKYEPIFLD 145

Query: 172 IYLTQ-------PSSSISTEINSAL--VLKVSWITFLLAKGEVLQMEDDLVISFQLMLCV 222
           I+          P S     I  ++  +    W  F+  KG    + DDLV S+ L+LC 
Sbjct: 146 IFQNPYEEPPKLPRSRKQRRIPCSVKDLFNFCWTLFVYTKGNFRMIGDDLVNSYHLLLCC 205

Query: 223 LDYFIK---LSPPM--LLKEPYKTAVIPINGSPRTPRRGQNRSARIAKQLENDTRIIEVL 277
           LD       + P    LL   +K      + +  T               E    II VL
Sbjct: 206 LDLIFANAIMCPNRQDLLNPSFKGLPSDFHTADFTAS-------------EEPPCIIAVL 252

Query: 278 CKEHECNIDEVKNV---YFKNFIPFMNSLGLVTSNGLPEVEN-------LSKRYEEIYLK 327
           C+ H+  + E K +   YFK +I  +    ++    L ++ +       ++K YEE  L 
Sbjct: 253 CELHDGLLVEAKGIKEHYFKPYISKLFDRKILKGECLLDLSSFTDNSKAVNKEYEEYVLT 312

Query: 328 NKDLDARLFLDHDKTLQTDSIDSFETQRTPRKSNLDEEVNV---IPPH------------ 372
             D D R+FL  D   +  +   F T+ TP    L  + NV   +  H            
Sbjct: 313 VGDFDERIFLGADAEEEIGTPRKF-TRDTP-LGKLTAQANVEYNLQQHFEKKRSFAPSTP 370

Query: 373 --------------TPVRTVMNTIQQLMMILNSASDQPSENLISYFNNCTVNPKESILKR 418
                         TPV +   ++ +L  I+    + PS+ LI+ F +C  NP E+I+K 
Sbjct: 371 LTGRRYLREKEAVITPVASATQSVSRLQSIVAGLKNAPSDQLINIFESCVRNPVENIMKI 430

Query: 419 VKDIGYIFKEKFAKAVGQ---GCVEIGSQRYKLGVRLYYRVMESMLKSEEERLSIQNFSK 475
           +K IG  F + + ++  +     ++    R KL   LYY+++E+++  E  RL   + S 
Sbjct: 431 LKGIGETFCQHYTQSTDEQPGSHIDFAVNRLKLAEILYYKILETVMVQETRRLHGMDMSV 490

Query: 476 LLNDNIFHMSLLACALEVVMATYSRSTSQNLDSGTDLSFPWILNVLNLKAFDFYKVIESF 535
           LL  +IFH SL+AC LE+V+  YS          +  +FPWI+ VLNL+ F FYKVIE  
Sbjct: 491 LLEQDIFHRSLMACCLEIVLFAYS----------SPRTFPWIIEVLNLQPFYFYKVIEVV 540

Query: 536 IKAEGNLTREMIKHLERCEHRIMESLAWLSDSPLFDLIKQSKDREGPTDHLESACPLNLP 595
           I++E  L+R+M+KHL   E +I+ESLAW  DS L++ ++ S ++    +  E   P N  
Sbjct: 541 IRSEEGLSRDMVKHLNSIEEQILESLAWSHDSALWEALQVSANKVPTCE--EVIFPNNFE 598

Query: 596 LQNNHTAAD----MYLSPVRSPKKK 616
             N          M +SP+  P+ K
Sbjct: 599 TGNGGNVQGHLPLMPMSPLMHPRVK 623



 Score =  111 bits (277), Expect = 4e-24
 Identities = 91/293 (31%), Positives = 133/293 (45%), Gaps = 66/293 (22%)

Query: 594  LPLQNNHTAADMYLSPVRSPKKK---GSTTRVNSTANAETQATSAFQTQKPLKSTSLSLF 650
            +PL  N        SPV          S  + N T   E  +T      +P ++ SL+LF
Sbjct: 735  IPLSMNTNQESKVKSPVSLTAHSLIGASPKQTNLTKAQEVHSTGI---NRPKRTGSLALF 791

Query: 651  YKKVYRLAYLRLNTLCERLLSEHPELEHIIWTLFQHTLQNEYELMRDRHLDQIMMCSMYG 710
            Y+KVY LA +RL  LC +L   + EL   IWT F+ TL +  +LM+DRHLDQ+++C+ Y 
Sbjct: 792  YRKVYHLASVRLRDLCLKLDVSN-ELRRKIWTCFEFTLVHCPDLMKDRHLDQLLLCAFYI 850

Query: 711  ICKVKNIDLKFKIIVTAYKDLPHAVQETFKRVLIK------------------------- 745
            + KV   +  F+ I+ +Y++ P A    ++ VL+K                         
Sbjct: 851  MAKVTKEERTFQEIMKSYRNQPQANSHVYRSVLLKSIPREVVAYNKNINDDFEMIDCDLE 910

Query: 746  -------------EEEYDSIIVFYNSVFMQRLKTNILQYASTR------PPTLSPIPHIP 786
                         +EE   +I FYN++++ R+K+  L+Y           P LSP PHI 
Sbjct: 911  DATKTPDCSSGPVKEERGDLIKFYNTIYVGRVKSFALKYDLANQDHMMDAPPLSPFPHIK 970

Query: 787  RSPYKFPSSPLRI-PGGNIYISPLKSPYKISEGLPTPTKMTPRSRILVSIGES 838
            +     P SP RI    +IYI    SP+K   GL      TPRS +L     S
Sbjct: 971  QQ----PGSPRRISQQHSIYI----SPHKNGSGL------TPRSALLYKFNGS 1009


>gi|55956904 mitogen-activated protein kinase kinase kinase 4
          isoform a [Homo sapiens]
          Length = 1608

 Score = 48.5 bits (114), Expect = 3e-05
 Identities = 21/35 (60%), Positives = 23/35 (65%)

Query: 6  PRKTAATAAAAAAEPPAPPPPPPPEEDPEQDSGPE 40
          P   A T AAA  EPP PPPPPPP  +PE +S PE
Sbjct: 11 PPAFAVTPAAAMEEPPPPPPPPPPPPEPETESEPE 45


>gi|55956902 mitogen-activated protein kinase kinase kinase 4
          isoform b [Homo sapiens]
          Length = 1558

 Score = 48.5 bits (114), Expect = 3e-05
 Identities = 21/35 (60%), Positives = 23/35 (65%)

Query: 6  PRKTAATAAAAAAEPPAPPPPPPPEEDPEQDSGPE 40
          P   A T AAA  EPP PPPPPPP  +PE +S PE
Sbjct: 11 PPAFAVTPAAAMEEPPPPPPPPPPPPEPETESEPE 45


>gi|110347459 MYC-associated zinc finger protein isoform 2 [Homo
           sapiens]
          Length = 493

 Score = 41.6 bits (96), Expect = 0.003
 Identities = 16/37 (43%), Positives = 20/37 (54%)

Query: 3   PKTPRKTAATAAAAAAEPPAPPPPPPPEEDPEQDSGP 39
           P  P   +    AA  +PPAPPPPPPP   P  ++ P
Sbjct: 113 PPAPAAASTVDTAALKQPPAPPPPPPPVSAPAAEAAP 149



 Score = 31.2 bits (69), Expect = 4.7
 Identities = 19/47 (40%), Positives = 19/47 (40%), Gaps = 13/47 (27%)

Query: 10  AATAAAAAAEPPAP-------------PPPPPPEEDPEQDSGPEDLP 43
           AA AAA AA PPAP             PP PPP   P      E  P
Sbjct: 103 AAAAAAVAAAPPAPAAASTVDTAALKQPPAPPPPPPPVSAPAAEAAP 149


>gi|110347461 MYC-associated zinc finger protein isoform 1 [Homo
           sapiens]
          Length = 477

 Score = 41.6 bits (96), Expect = 0.003
 Identities = 16/37 (43%), Positives = 20/37 (54%)

Query: 3   PKTPRKTAATAAAAAAEPPAPPPPPPPEEDPEQDSGP 39
           P  P   +    AA  +PPAPPPPPPP   P  ++ P
Sbjct: 113 PPAPAAASTVDTAALKQPPAPPPPPPPVSAPAAEAAP 149



 Score = 31.2 bits (69), Expect = 4.7
 Identities = 19/47 (40%), Positives = 19/47 (40%), Gaps = 13/47 (27%)

Query: 10  AATAAAAAAEPPAP-------------PPPPPPEEDPEQDSGPEDLP 43
           AA AAA AA PPAP             PP PPP   P      E  P
Sbjct: 103 AAAAAAVAAAPPAPAAASTVDTAALKQPPAPPPPPPPVSAPAAEAAP 149


>gi|17986273 fast skeletal myosin alkali light chain 1 isoform 1f
          [Homo sapiens]
          Length = 194

 Score = 41.6 bits (96), Expect = 0.003
 Identities = 21/56 (37%), Positives = 31/56 (55%), Gaps = 3/56 (5%)

Query: 2  PPKTPRKTAATAAAAAAEPPAPPPPPPPEEDPEQDSGPEDLPLVRLEFEETEEPDF 57
          P K  +K  A AAAA A  PAP P P P +  E+     DL  +++EF + ++ +F
Sbjct: 3  PKKDVKKPVAAAAAAPAPAPAPAPAPAPAKPKEEKI---DLSAIKIEFSKEQQDEF 55


>gi|56118221 amyloid beta (A4) precursor protein-binding, family B,
           member 1 interacting protein [Homo sapiens]
          Length = 666

 Score = 40.8 bits (94), Expect = 0.006
 Identities = 21/62 (33%), Positives = 25/62 (40%), Gaps = 4/62 (6%)

Query: 3   PKTPRKTAATAAAAAAEPP----APPPPPPPEEDPEQDSGPEDLPLVRLEFEETEEPDFT 58
           P TP K   T       PP     PPPPPPP +DPE    P D      +F     P + 
Sbjct: 532 PATPLKAKGTGGGGLPAPPDDFLPPPPPPPPLDDPELPPPPPDFMEPPPDFVPPPPPSYA 591

Query: 59  AL 60
            +
Sbjct: 592 GI 593



 Score = 31.2 bits (69), Expect = 4.7
 Identities = 16/37 (43%), Positives = 18/37 (48%), Gaps = 1/37 (2%)

Query: 2   PPKTPRKTAATAAAAAAE-PPAPPPPPPPEEDPEQDS 37
           P   P    + A  A +E PP PPPPP P   P  DS
Sbjct: 580 PDFVPPPPPSYAGIAGSELPPPPPPPPAPAPAPVPDS 616


>gi|25777598 diacylglycerol kinase, delta 130kDa isoform 2 [Homo
          sapiens]
          Length = 1214

 Score = 40.0 bits (92), Expect = 0.010
 Identities = 20/34 (58%), Positives = 20/34 (58%), Gaps = 2/34 (5%)

Query: 10 AATAAAAAAEPPAPPPPPPPEEDPEQDSGPEDLP 43
          AA A A    PP PPPPPPPEE    DS PE  P
Sbjct: 2  AAAAGAPPPGPPQPPPPPPPEE--SSDSEPEAEP 33


>gi|39930517 sterile alpha motif domain containing 1 [Homo sapiens]
          Length = 538

 Score = 40.0 bits (92), Expect = 0.010
 Identities = 21/42 (50%), Positives = 23/42 (54%), Gaps = 2/42 (4%)

Query: 2   PPKTPRKTAATAAAAAAEPPAPPPPPPPEEDPEQDSGPEDLP 43
           PP  PR+ A   A AA EPP PPPP PP   P+Q   P   P
Sbjct: 192 PPAGPRR-APPPAVAAREPPLPPPPQPP-APPQQQQPPPPQP 231



 Score = 37.7 bits (86), Expect = 0.050
 Identities = 18/42 (42%), Positives = 19/42 (45%)

Query: 2   PPKTPRKTAATAAAAAAEPPAPPPPPPPEEDPEQDSGPEDLP 43
           PP  PR      AAAAA  P P P PPP   P   + P   P
Sbjct: 108 PPAPPRAPRGAPAAAAAAAPPPTPAPPPPPAPVAAAAPARAP 149


>gi|61743948 abl-interactor 1 isoform d [Homo sapiens]
          Length = 476

 Score = 39.7 bits (91), Expect = 0.013
 Identities = 20/60 (33%), Positives = 28/60 (46%), Gaps = 8/60 (13%)

Query: 2   PPKTPRKT--------AATAAAAAAEPPAPPPPPPPEEDPEQDSGPEDLPLVRLEFEETE 53
           PP  P+ T         A      A+ P PPPPPPP++ P  D  P   P   +++E+ E
Sbjct: 334 PPPMPQLTPQIPLTGFVARVQENIADSPTPPPPPPPDDIPMFDDSPPPPPPPPVDYEDEE 393


>gi|61743944 abl-interactor 1 isoform b [Homo sapiens]
          Length = 481

 Score = 39.7 bits (91), Expect = 0.013
 Identities = 20/60 (33%), Positives = 28/60 (46%), Gaps = 8/60 (13%)

Query: 2   PPKTPRKT--------AATAAAAAAEPPAPPPPPPPEEDPEQDSGPEDLPLVRLEFEETE 53
           PP  P+ T         A      A+ P PPPPPPP++ P  D  P   P   +++E+ E
Sbjct: 339 PPPMPQLTPQIPLTGFVARVQENIADSPTPPPPPPPDDIPMFDDSPPPPPPPPVDYEDEE 398


>gi|61743942 abl-interactor 1 isoform a [Homo sapiens]
          Length = 508

 Score = 39.7 bits (91), Expect = 0.013
 Identities = 20/60 (33%), Positives = 28/60 (46%), Gaps = 8/60 (13%)

Query: 2   PPKTPRKT--------AATAAAAAAEPPAPPPPPPPEEDPEQDSGPEDLPLVRLEFEETE 53
           PP  P+ T         A      A+ P PPPPPPP++ P  D  P   P   +++E+ E
Sbjct: 366 PPPMPQLTPQIPLTGFVARVQENIADSPTPPPPPPPDDIPMFDDSPPPPPPPPVDYEDEE 425


>gi|4507909 Wiskott-Aldrich syndrome protein [Homo sapiens]
          Length = 502

 Score = 39.3 bits (90), Expect = 0.017
 Identities = 19/48 (39%), Positives = 21/48 (43%), Gaps = 5/48 (10%)

Query: 2   PPKTPRKTAATAAA-----AAAEPPAPPPPPPPEEDPEQDSGPEDLPL 44
           PP  P  T  +         A  PP PPPPPPP   P   +GP   PL
Sbjct: 368 PPPPPPATGRSGPLPPPPPGAGGPPMPPPPPPPPPPPSSGNGPAPPPL 415


>gi|122937496 WAS/WASL interacting protein family, member 3 [Homo
           sapiens]
          Length = 483

 Score = 39.3 bits (90), Expect = 0.017
 Identities = 22/57 (38%), Positives = 25/57 (43%), Gaps = 12/57 (21%)

Query: 1   MPPKTPRKTAATAAAAAAE------------PPAPPPPPPPEEDPEQDSGPEDLPLV 45
           +PP +PR    + A  AA             PP PPPPPPP   P   S P   PLV
Sbjct: 145 IPPASPRLGNTSEAHGAARTAPPRPNVPAPPPPTPPPPPPPLPPPLPSSSPIKTPLV 201



 Score = 32.0 bits (71), Expect = 2.7
 Identities = 13/31 (41%), Positives = 13/31 (41%)

Query: 3   PKTPRKTAATAAAAAAEPPAPPPPPPPEEDP 33
           P T       A      PP PPPPPPP   P
Sbjct: 206 PLTKGNLPVVAPPVPCAPPPPPPPPPPTPPP 236



 Score = 31.6 bits (70), Expect = 3.6
 Identities = 13/19 (68%), Positives = 14/19 (73%)

Query: 11  ATAAAAAAEPPAPPPPPPP 29
           A+ A  A EPPAPPPP PP
Sbjct: 280 ASPAQDAQEPPAPPPPLPP 298


>gi|33188449 serine/arginine-rich protein-specific kinase 2
          isoform a [Homo sapiens]
          Length = 699

 Score = 38.9 bits (89), Expect = 0.022
 Identities = 18/52 (34%), Positives = 25/52 (48%)

Query: 4  KTPRKTAATAAAAAAEPPAPPPPPPPEEDPEQDSGPEDLPLVRLEFEETEEP 55
          K P+K      A    PP PPPPPPP   P+      +  ++  + EE E+P
Sbjct: 20 KHPKKPEPQQKAPLVPPPPPPPPPPPPPLPDPTPPEPEEEILGSDDEEQEDP 71



 Score = 32.3 bits (72), Expect = 2.1
 Identities = 15/42 (35%), Positives = 20/42 (47%)

Query: 21 PAPPPPPPPEEDPEQDSGPEDLPLVRLEFEETEEPDFTALCQ 62
          P PPPPPPP   P  D  P +     L  ++ E+ D    C+
Sbjct: 35 PPPPPPPPPPPPPLPDPTPPEPEEEILGSDDEEQEDPADYCK 76


>gi|61743946 abl-interactor 1 isoform c [Homo sapiens]
          Length = 452

 Score = 38.9 bits (89), Expect = 0.022
 Identities = 15/36 (41%), Positives = 22/36 (61%)

Query: 18  AEPPAPPPPPPPEEDPEQDSGPEDLPLVRLEFEETE 53
           A+ P PPPPPPP++ P  D  P   P   +++E+ E
Sbjct: 334 ADSPTPPPPPPPDDIPMFDDSPPPPPPPPVDYEDEE 369


>gi|126090663 zinc finger homeodomain 4 [Homo sapiens]
          Length = 3571

 Score = 38.9 bits (89), Expect = 0.022
 Identities = 18/46 (39%), Positives = 20/46 (43%)

Query: 2    PPKTPRKTAATAAAAAAEPPAPPPPPPPEEDPEQDSGPEDLPLVRL 47
            P K P   +    A    PP PPPPPPP   P     P   P V+L
Sbjct: 1979 PVKIPNTVSTPLQAPPPTPPPPPPPPPPPPPPPPPPPPSAPPQVQL 2024



 Score = 34.3 bits (77), Expect = 0.55
 Identities = 20/45 (44%), Positives = 20/45 (44%), Gaps = 7/45 (15%)

Query: 2    PPKTPRKTAATAAAAAAEPPAPPPPPPPEEDPEQDSGPE--DLPL 44
            PP TP             PP PPPPPPP   P Q   P   DLPL
Sbjct: 1993 PPPTP-----PPPPPPPPPPPPPPPPPPPSAPPQVQLPVSLDLPL 2032



 Score = 31.2 bits (69), Expect = 4.7
 Identities = 24/88 (27%), Positives = 36/88 (40%), Gaps = 4/88 (4%)

Query: 3    PKTPRKTAATAAAAAAEPPAPPPPPPPEEDPEQDSGPEDLPLVRLEFEETE-EPDFTALC 61
            P     +A T       PP PPPPPPP   P      +       E E+ + +P+     
Sbjct: 3101 PALSLSSAPTKPLLQTPPPPPPPPPPP---PSSSLSGQQTEQQNKESEKKQTKPNKVKKI 3157

Query: 62   QKLKIPDHVRERAWLTWEKVSSVDGVLG 89
            ++ ++     E+     EK+SS   VLG
Sbjct: 3158 KEEELEATKPEKHPKKEEKISSALSVLG 3185



 Score = 30.8 bits (68), Expect = 6.1
 Identities = 14/26 (53%), Positives = 15/26 (57%), Gaps = 2/26 (7%)

Query: 20   PPAPPPPPPPEEDPEQDS--GPEDLP 43
            PP PPPPPP    P Q S  GP  +P
Sbjct: 1958 PPPPPPPPPLPPAPPQPSSMGPVKIP 1983


>gi|117938310 sine oculis binding protein homolog [Homo sapiens]
          Length = 873

 Score = 38.9 bits (89), Expect = 0.022
 Identities = 22/55 (40%), Positives = 29/55 (52%), Gaps = 2/55 (3%)

Query: 7   RKTAATAAAAAAEPPAPPPPPPPEEDPEQDSGPEDLPLVRLEFEETEEPDFTALC 61
           R  AA  A +A  PP  PPPPPP   P++   PE+ P V  E E  +E +  + C
Sbjct: 728 RGAAAEGAKSAEPPPEQPPPPPPPAPPKKLLSPEE-PAVS-ELESVKENNCASNC 780


>gi|46048439 N-acetyltransferase 6 [Homo sapiens]
          Length = 308

 Score = 38.5 bits (88), Expect = 0.029
 Identities = 20/52 (38%), Positives = 24/52 (46%), Gaps = 3/52 (5%)

Query: 2   PPKTPRKTAATAAAAAAEPPAPPPPPPPE---EDPEQDSGPEDLPLVRLEFE 50
           P K P  TA  A      PP PPPPP PE     P   SGP    L+  +++
Sbjct: 243 PRKAPNLTAQAAPRGPKGPPLPPPPPLPECLTISPPVPSGPPSKSLLETQYQ 294


>gi|148229134 ring finger and KH domain containing 2 [Homo
          sapiens]
          Length = 659

 Score = 38.5 bits (88), Expect = 0.029
 Identities = 18/40 (45%), Positives = 19/40 (47%)

Query: 1  MPPKTPRKTAATAAAAAAEPPAPPPPPPPEEDPEQDSGPE 40
          MP  +    A  AA A    P PPPPPPP   P    GPE
Sbjct: 1  MPSGSSAALALAAAPAPLPQPPPPPPPPPPPLPPPSGGPE 40


>gi|195947369 junction-mediating and regulatory protein [Homo
           sapiens]
          Length = 988

 Score = 38.1 bits (87), Expect = 0.038
 Identities = 20/38 (52%), Positives = 21/38 (55%), Gaps = 2/38 (5%)

Query: 20  PPAPPPPPPPEEDPEQDSGPEDL--PLVRLEFEETEEP 55
           PP PPPPPPP     +DSGPE L   L R E  E   P
Sbjct: 815 PPPPPPPPPPPLPVAKDSGPETLEKDLPRKEGNEKRIP 852


>gi|156523246 proline-rich transmembrane protein 2 [Homo sapiens]
          Length = 340

 Score = 38.1 bits (87), Expect = 0.038
 Identities = 16/39 (41%), Positives = 21/39 (53%)

Query: 17  AAEPPAPPPPPPPEEDPEQDSGPEDLPLVRLEFEETEEP 55
           +A PP P P P P+ DP  DS P   P ++ E    E+P
Sbjct: 128 SAAPPEPAPEPAPQPDPRPDSQPTPKPALQPELPTQEDP 166


>gi|164698460 mannosidase, endo-alpha-like isoform 3 [Homo
          sapiens]
          Length = 457

 Score = 38.1 bits (87), Expect = 0.038
 Identities = 19/38 (50%), Positives = 20/38 (52%), Gaps = 2/38 (5%)

Query: 4  KTPRKTAATAAAAAAEPPAPPPPPPPEE--DPEQDSGP 39
          + P    A AA A A P APPPPPPP    DP    GP
Sbjct: 49 RRPEGAPAPAARAPAAPAAPPPPPPPPRTADPGGSPGP 86


>gi|72534766 mannosidase, endo-alpha-like isoform 1 [Homo sapiens]
          Length = 250

 Score = 38.1 bits (87), Expect = 0.038
 Identities = 19/38 (50%), Positives = 20/38 (52%), Gaps = 2/38 (5%)

Query: 4  KTPRKTAATAAAAAAEPPAPPPPPPPEE--DPEQDSGP 39
          + P    A AA A A P APPPPPPP    DP    GP
Sbjct: 49 RRPEGAPAPAARAPAAPAAPPPPPPPPRTADPGGSPGP 86


>gi|158534059 formin binding protein 4 [Homo sapiens]
          Length = 1017

 Score = 37.7 bits (86), Expect = 0.050
 Identities = 20/55 (36%), Positives = 25/55 (45%), Gaps = 7/55 (12%)

Query: 1   MPPKTPRKTAATAAAAAAEPPAPPPPPPPEEDPEQDSGPEDLPLVRLEFEETEEP 55
           + P  P +           PP PPPPPPP ED E       +  V +E E +EEP
Sbjct: 703 LQPPLPLEMPPPPPPPPESPPPPPPPPPPAEDGE-------IQEVEMEDEGSEEP 750



 Score = 34.7 bits (78), Expect = 0.42
 Identities = 14/31 (45%), Positives = 15/31 (48%)

Query: 11  ATAAAAAAEPPAPPPPPPPEEDPEQDSGPED 41
           A   A   EPP PPPPPPP   P     P +
Sbjct: 896 AVPTATIIEPPPPPPPPPPPPPPAPKMPPPE 926



 Score = 33.9 bits (76), Expect = 0.72
 Identities = 14/34 (41%), Positives = 16/34 (47%)

Query: 1   MPPKTPRKTAATAAAAAAEPPAPPPPPPPEEDPE 34
           + P   R    TA      PP PPPPPPP   P+
Sbjct: 888 LQPVQARGAVPTATIIEPPPPPPPPPPPPPPAPK 921



 Score = 32.7 bits (73), Expect = 1.6
 Identities = 19/57 (33%), Positives = 23/57 (40%), Gaps = 3/57 (5%)

Query: 3   PKTPRKTAATAAAAAAEPPAP---PPPPPPEEDPEQDSGPEDLPLVRLEFEETEEPD 56
           P TP  T   +     +PP P   PPPPPP  +      P   P    E +E E  D
Sbjct: 688 PLTPFWTLLQSNVPVLQPPLPLEMPPPPPPPPESPPPPPPPPPPAEDGEIQEVEMED 744



 Score = 30.8 bits (68), Expect = 6.1
 Identities = 16/54 (29%), Positives = 22/54 (40%)

Query: 10  AATAAAAAAEPPAPPPPPPPEEDPEQDSGPEDLPLVRLEFEETEEPDFTALCQK 63
           A   A     PP PPPPPPP     +   PE     R +  +  +    +L +K
Sbjct: 896 AVPTATIIEPPPPPPPPPPPPPPAPKMPPPEKTKKGRKDKAKKSKTKMPSLVKK 949


>gi|149944526 additional sex combs like 3 [Homo sapiens]
          Length = 2248

 Score = 37.7 bits (86), Expect = 0.050
 Identities = 19/64 (29%), Positives = 25/64 (39%)

Query: 2    PPKTPRKTAATAAAAAAEPPAPPPPPPPEEDPEQDSGPEDLPLVRLEFEETEEPDFTALC 61
            PP  P        A    PP PPP PPP  + E  S  +  P+     +    P  T +C
Sbjct: 2017 PPPPPPPPPPPPLALPPPPPPPPPLPPPLPNAEVPSDQKQPPVTMETTKRLSWPQSTGIC 2076

Query: 62   QKLK 65
              +K
Sbjct: 2077 SNIK 2080



 Score = 32.7 bits (73), Expect = 1.6
 Identities = 19/49 (38%), Positives = 20/49 (40%), Gaps = 6/49 (12%)

Query: 1    MPPKTPRKTAATA------AAAAAEPPAPPPPPPPEEDPEQDSGPEDLP 43
            MP K   +   TA      A     PP PPPPPPP   P     P  LP
Sbjct: 1994 MPMKEGDEVGGTAHTMPNKALVHPPPPPPPPPPPPLALPPPPPPPPPLP 2042


>gi|5730045 solute carrier family 16, member 2 [Homo sapiens]
          Length = 613

 Score = 37.4 bits (85), Expect = 0.065
 Identities = 19/40 (47%), Positives = 21/40 (52%), Gaps = 2/40 (5%)

Query: 21  PAPPPPPPPEEDPEQDSGPEDLPLVRLEF--EETEEPDFT 58
           P P P PPPE  PE    P+  PL  LEF  E   EP+ T
Sbjct: 115 PEPVPVPPPEPQPEPQPLPDPAPLPELEFESERVHEPEPT 154


  Database: hs.faa
    Posted date:  Aug 4, 2009  4:42 PM
  Number of letters in database: 18,247,518
  Number of sequences in database:  37,866
  
Lambda     K      H
   0.317    0.133    0.384 

Gapped
Lambda     K      H
   0.267   0.0410    0.140 


Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Hits to DB: 36,977,388
Number of Sequences: 37866
Number of extensions: 1817218
Number of successful extensions: 26838
Number of sequences better than 10.0: 30
Number of HSP's better than 10.0 without gapping: 289
Number of HSP's successfully gapped in prelim test: 117
Number of HSP's that attempted gapping in prelim test: 19975
Number of HSP's gapped (non-prelim): 4769
length of query: 928
length of database: 18,247,518
effective HSP length: 112
effective length of query: 816
effective length of database: 14,006,526
effective search space: 11429325216
effective search space used: 11429325216
T: 11
A: 40
X1: 16 ( 7.3 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 41 (21.7 bits)
S2: 67 (30.4 bits)

Search results were obtained with NCBI BLAST and RefSeq entries.


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Guide to the Human Genome
Copyright © 2010 by Stewart Scherer. All rights reserved.

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