BLASTP 2.2.11 [Jun-05-2005] Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer, Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), "Gapped BLAST and PSI-BLAST: a new generation of protein database search programs", Nucleic Acids Res. 25:3389-3402. Query= gi|108773787 retinoblastoma 1 [Homo sapiens] (928 letters) Database: hs.faa 37,866 sequences; 18,247,518 total letters Searching..................................................done Score E Sequences producing significant alignments: (bits) Value gi|108773787 retinoblastoma 1 [Homo sapiens] 1852 0.0 gi|172072597 retinoblastoma-like 2 (p130) [Homo sapiens] 194 2e-49 gi|34577079 retinoblastoma-like protein 1 isoform a [Homo sapiens] 181 3e-45 gi|34577077 retinoblastoma-like protein 1 isoform b [Homo sapiens] 181 3e-45 gi|55956904 mitogen-activated protein kinase kinase kinase 4 iso... 49 3e-05 gi|55956902 mitogen-activated protein kinase kinase kinase 4 iso... 49 3e-05 gi|110347459 MYC-associated zinc finger protein isoform 2 [Homo ... 42 0.003 gi|110347461 MYC-associated zinc finger protein isoform 1 [Homo ... 42 0.003 gi|17986273 fast skeletal myosin alkali light chain 1 isoform 1f... 42 0.003 gi|56118221 amyloid beta (A4) precursor protein-binding, family ... 41 0.006 gi|25777598 diacylglycerol kinase, delta 130kDa isoform 2 [Homo ... 40 0.010 gi|39930517 sterile alpha motif domain containing 1 [Homo sapiens] 40 0.010 gi|61743948 abl-interactor 1 isoform d [Homo sapiens] 40 0.013 gi|61743944 abl-interactor 1 isoform b [Homo sapiens] 40 0.013 gi|61743942 abl-interactor 1 isoform a [Homo sapiens] 40 0.013 gi|4507909 Wiskott-Aldrich syndrome protein [Homo sapiens] 39 0.017 gi|122937496 WAS/WASL interacting protein family, member 3 [Homo... 39 0.017 gi|33188449 serine/arginine-rich protein-specific kinase 2 isofo... 39 0.022 gi|61743946 abl-interactor 1 isoform c [Homo sapiens] 39 0.022 gi|126090663 zinc finger homeodomain 4 [Homo sapiens] 39 0.022 gi|117938310 sine oculis binding protein homolog [Homo sapiens] 39 0.022 gi|46048439 N-acetyltransferase 6 [Homo sapiens] 39 0.029 gi|148229134 ring finger and KH domain containing 2 [Homo sapiens] 39 0.029 gi|195947369 junction-mediating and regulatory protein [Homo sap... 38 0.038 gi|156523246 proline-rich transmembrane protein 2 [Homo sapiens] 38 0.038 gi|164698460 mannosidase, endo-alpha-like isoform 3 [Homo sapiens] 38 0.038 gi|72534766 mannosidase, endo-alpha-like isoform 1 [Homo sapiens] 38 0.038 gi|158534059 formin binding protein 4 [Homo sapiens] 38 0.050 gi|149944526 additional sex combs like 3 [Homo sapiens] 38 0.050 gi|5730045 solute carrier family 16, member 2 [Homo sapiens] 37 0.065 >gi|108773787 retinoblastoma 1 [Homo sapiens] Length = 928 Score = 1852 bits (4797), Expect = 0.0 Identities = 928/928 (100%), Positives = 928/928 (100%) Query: 1 MPPKTPRKTAATAAAAAAEPPAPPPPPPPEEDPEQDSGPEDLPLVRLEFEETEEPDFTAL 60 MPPKTPRKTAATAAAAAAEPPAPPPPPPPEEDPEQDSGPEDLPLVRLEFEETEEPDFTAL Sbjct: 1 MPPKTPRKTAATAAAAAAEPPAPPPPPPPEEDPEQDSGPEDLPLVRLEFEETEEPDFTAL 60 Query: 61 CQKLKIPDHVRERAWLTWEKVSSVDGVLGGYIQKKKELWGICIFIAAVDLDEMSFTFTEL 120 CQKLKIPDHVRERAWLTWEKVSSVDGVLGGYIQKKKELWGICIFIAAVDLDEMSFTFTEL Sbjct: 61 CQKLKIPDHVRERAWLTWEKVSSVDGVLGGYIQKKKELWGICIFIAAVDLDEMSFTFTEL 120 Query: 121 QKNIEISVHKFFNLLKEIDTSTKVDNAMSRLLKKYDVLFALFSKLERTCELIYLTQPSSS 180 QKNIEISVHKFFNLLKEIDTSTKVDNAMSRLLKKYDVLFALFSKLERTCELIYLTQPSSS Sbjct: 121 QKNIEISVHKFFNLLKEIDTSTKVDNAMSRLLKKYDVLFALFSKLERTCELIYLTQPSSS 180 Query: 181 ISTEINSALVLKVSWITFLLAKGEVLQMEDDLVISFQLMLCVLDYFIKLSPPMLLKEPYK 240 ISTEINSALVLKVSWITFLLAKGEVLQMEDDLVISFQLMLCVLDYFIKLSPPMLLKEPYK Sbjct: 181 ISTEINSALVLKVSWITFLLAKGEVLQMEDDLVISFQLMLCVLDYFIKLSPPMLLKEPYK 240 Query: 241 TAVIPINGSPRTPRRGQNRSARIAKQLENDTRIIEVLCKEHECNIDEVKNVYFKNFIPFM 300 TAVIPINGSPRTPRRGQNRSARIAKQLENDTRIIEVLCKEHECNIDEVKNVYFKNFIPFM Sbjct: 241 TAVIPINGSPRTPRRGQNRSARIAKQLENDTRIIEVLCKEHECNIDEVKNVYFKNFIPFM 300 Query: 301 NSLGLVTSNGLPEVENLSKRYEEIYLKNKDLDARLFLDHDKTLQTDSIDSFETQRTPRKS 360 NSLGLVTSNGLPEVENLSKRYEEIYLKNKDLDARLFLDHDKTLQTDSIDSFETQRTPRKS Sbjct: 301 NSLGLVTSNGLPEVENLSKRYEEIYLKNKDLDARLFLDHDKTLQTDSIDSFETQRTPRKS 360 Query: 361 NLDEEVNVIPPHTPVRTVMNTIQQLMMILNSASDQPSENLISYFNNCTVNPKESILKRVK 420 NLDEEVNVIPPHTPVRTVMNTIQQLMMILNSASDQPSENLISYFNNCTVNPKESILKRVK Sbjct: 361 NLDEEVNVIPPHTPVRTVMNTIQQLMMILNSASDQPSENLISYFNNCTVNPKESILKRVK 420 Query: 421 DIGYIFKEKFAKAVGQGCVEIGSQRYKLGVRLYYRVMESMLKSEEERLSIQNFSKLLNDN 480 DIGYIFKEKFAKAVGQGCVEIGSQRYKLGVRLYYRVMESMLKSEEERLSIQNFSKLLNDN Sbjct: 421 DIGYIFKEKFAKAVGQGCVEIGSQRYKLGVRLYYRVMESMLKSEEERLSIQNFSKLLNDN 480 Query: 481 IFHMSLLACALEVVMATYSRSTSQNLDSGTDLSFPWILNVLNLKAFDFYKVIESFIKAEG 540 IFHMSLLACALEVVMATYSRSTSQNLDSGTDLSFPWILNVLNLKAFDFYKVIESFIKAEG Sbjct: 481 IFHMSLLACALEVVMATYSRSTSQNLDSGTDLSFPWILNVLNLKAFDFYKVIESFIKAEG 540 Query: 541 NLTREMIKHLERCEHRIMESLAWLSDSPLFDLIKQSKDREGPTDHLESACPLNLPLQNNH 600 NLTREMIKHLERCEHRIMESLAWLSDSPLFDLIKQSKDREGPTDHLESACPLNLPLQNNH Sbjct: 541 NLTREMIKHLERCEHRIMESLAWLSDSPLFDLIKQSKDREGPTDHLESACPLNLPLQNNH 600 Query: 601 TAADMYLSPVRSPKKKGSTTRVNSTANAETQATSAFQTQKPLKSTSLSLFYKKVYRLAYL 660 TAADMYLSPVRSPKKKGSTTRVNSTANAETQATSAFQTQKPLKSTSLSLFYKKVYRLAYL Sbjct: 601 TAADMYLSPVRSPKKKGSTTRVNSTANAETQATSAFQTQKPLKSTSLSLFYKKVYRLAYL 660 Query: 661 RLNTLCERLLSEHPELEHIIWTLFQHTLQNEYELMRDRHLDQIMMCSMYGICKVKNIDLK 720 RLNTLCERLLSEHPELEHIIWTLFQHTLQNEYELMRDRHLDQIMMCSMYGICKVKNIDLK Sbjct: 661 RLNTLCERLLSEHPELEHIIWTLFQHTLQNEYELMRDRHLDQIMMCSMYGICKVKNIDLK 720 Query: 721 FKIIVTAYKDLPHAVQETFKRVLIKEEEYDSIIVFYNSVFMQRLKTNILQYASTRPPTLS 780 FKIIVTAYKDLPHAVQETFKRVLIKEEEYDSIIVFYNSVFMQRLKTNILQYASTRPPTLS Sbjct: 721 FKIIVTAYKDLPHAVQETFKRVLIKEEEYDSIIVFYNSVFMQRLKTNILQYASTRPPTLS 780 Query: 781 PIPHIPRSPYKFPSSPLRIPGGNIYISPLKSPYKISEGLPTPTKMTPRSRILVSIGESFG 840 PIPHIPRSPYKFPSSPLRIPGGNIYISPLKSPYKISEGLPTPTKMTPRSRILVSIGESFG Sbjct: 781 PIPHIPRSPYKFPSSPLRIPGGNIYISPLKSPYKISEGLPTPTKMTPRSRILVSIGESFG 840 Query: 841 TSEKFQKINQMVCNSDRVLKRSAEGSNPPKPLKKLRFDIEGSDEADGSKHLPGESKFQQK 900 TSEKFQKINQMVCNSDRVLKRSAEGSNPPKPLKKLRFDIEGSDEADGSKHLPGESKFQQK Sbjct: 841 TSEKFQKINQMVCNSDRVLKRSAEGSNPPKPLKKLRFDIEGSDEADGSKHLPGESKFQQK 900 Query: 901 LAEMTSTRTRMQKQKMNDSMDTSNKEEK 928 LAEMTSTRTRMQKQKMNDSMDTSNKEEK Sbjct: 901 LAEMTSTRTRMQKQKMNDSMDTSNKEEK 928 >gi|172072597 retinoblastoma-like 2 (p130) [Homo sapiens] Length = 1139 Score = 194 bits (494), Expect = 2e-49 Identities = 176/700 (25%), Positives = 298/700 (42%), Gaps = 98/700 (14%) Query: 23 PPPPPPP-----EEDPEQDSGPEDLPLVRLEFEETEEPDFTALCQKLKIPDHVRERAWLT 77 PPPPPPP +E+ E D ED + F LC +L + + R AW + Sbjct: 10 PPPPPPPAAAASDEEEEDDGEAEDAAPPAESPTPQIQQRFDELCSRLNMDEAARAEAWDS 69 Query: 78 WEKVSSVDGVLGGYIQKKKELWGICIFIAAV----------DLDEMSFTFTELQKNIEIS 127 + +S + G + W C A ++ + T + K E S Sbjct: 70 YRSMSESYTLEGNDLH-----WLACALYVACRKSVPTVSKGTVEGNYVSLTRILKCSEQS 124 Query: 128 VHKFFNLLKEIDTSTKVD----NAMSRLLKKYDVLFALFSKLERTCELIYL----TQPSS 179 + +FFN +K+ + + RL + + V +F K E + I+ QP Sbjct: 125 LIEFFNKMKKWEDMANLPPHFRERTERLERNFTVSAVIFKKYEPIFQDIFKYPQEEQPRQ 184 Query: 180 SISTE-----INSALVLKVSWITFLLAKGEVLQMEDDLVISFQLMLCVLDYFIKLSPPML 234 + + + W+ F+ AKG + DDLV S+ L+LC LD L Sbjct: 185 QRGRKQRRQPCTVSEIFHFCWVLFIYAKGNFPMISDDLVNSYHLLLCALD----LVYGNA 240 Query: 235 LKEPYKTAVIPINGSPRTPRRGQNRSARIAKQLENDTRIIEVLCKEHECNIDEVKNVYFK 294 L+ + ++ +P ++ A+ +K + IIE LC H+ + E K + Sbjct: 241 LQCSNRKELV----NPNFKGLSEDFHAKDSKPSSDPPCIIEKLCSLHDGLVLEAKGIKEH 296 Query: 295 NFIPFMNSL--------------GLVTSNGLPE-VENLSKRYEEIYLKNKDLDARLFLDH 339 + P++ L G + E + ++K YEE L +LD R+FL Sbjct: 297 FWKPYIRKLYEKKLLKGKEENLTGFLEPGNFGESFKAINKAYEEYVLSVGNLDERIFLGE 356 Query: 340 DKTLQTDSI-----------------------DSFETQRTPRKSNLDEEVNVI----PPH 372 D + ++ F+ + R S V I P Sbjct: 357 DAEEEIGTLSRCLNAGSGTETAERVQMKNILQQHFDKSKALRISTPLTGVRYIKENSPCV 416 Query: 373 TPVRTVMNTIQQLMMILNSASDQPSENLISYFNNCTVNPKESILKRVKDIGYIFKEKFA- 431 TPV T +++ +L +L + PSE L C+ +P ++I R+K++ I+ + F Sbjct: 417 TPVSTATHSLSRLHTMLTGLRNAPSEKLEQILRTCSRDPTQAIANRLKEMFEIYSQHFQP 476 Query: 432 -KAVGQGCVEIGSQRYKLGVRLYYRVMESMLKSEEERLSIQNFSKLLNDNIFHMSLLACA 490 + EI S+ ++ LYY+V+ES+++ E++RL + S +L + FH SLLAC Sbjct: 477 DEDFSNCAKEIASKHFRFAEMLYYKVLESVIEQEQKRLGDMDLSGILEQDAFHRSLLACC 536 Query: 491 LEVVMATYSRSTSQNLDSGTDLSFPWILNVLNLKAFDFYKVIESFIKAEGNLTREMIKHL 550 LEVV +Y +FP+I + ++ + FYKVIE FI+AE L RE++KHL Sbjct: 537 LEVVTFSYKPPG----------NFPFITEIFDVPLYHFYKVIEVFIRAEDGLCREVVKHL 586 Query: 551 ERCEHRIMESLAWLSDSPLFDLIKQSKDREGPTDHLESACPLNLPLQNNHTAADMYLSPV 610 + E +I++ LAW +SPL++ I+ +++R + E P NL + A L+P Sbjct: 587 NQIEEQILDHLAWKPESPLWEKIRDNENRVPTCE--EVMPPQNLERADEICIAGSPLTPR 644 Query: 611 RSPKKKGSTTRVNSTANAETQATSAFQTQKPLKSTSLSLF 650 R + + T + + + T + + P +T LF Sbjct: 645 RVTEVRADTGGLGRSITSPTTLYDRY-SSPPASTTRRRLF 683 Score = 94.0 bits (232), Expect = 6e-19 Identities = 69/211 (32%), Positives = 106/211 (50%), Gaps = 18/211 (8%) Query: 596 LQNNHTAADMYLSPVRSPKKKGSTTRVNSTANAETQATSAFQTQKPLKSTSLSLFYKKVY 655 LQ A +SP +K+G + V S++N +P K++SLSLF++KVY Sbjct: 799 LQVPGQVAIQQISPGGQQQKQGQS--VTSSSN------------RPRKTSSLSLFFRKVY 844 Query: 656 RLAYLRLNTLCERLLSEHPELEHIIWTLFQHTLQNEYELMRDRHLDQIMMCSMYGICKVK 715 LA +RL LC +L EL IWT F+ ++ ELM DRHLDQ++MC++Y + KV Sbjct: 845 HLAAVRLRDLCAKL-DISDELRKKIWTCFEFSIIQCPELMMDRHLDQLLMCAIYVMAKVT 903 Query: 716 NIDLKFKIIVTAYKDLPHAVQETFKRVLIKEEEYDSIIVFYNSVFMQRLKTNILQYASTR 775 D F+ I+ Y+ P A + ++ VLIK + +S Q T + + ++R Sbjct: 904 KEDKSFQNIMRCYRTQPQARSQVYRSVLIKGKRKRRNSGSSDSRSHQNSPTELNKDRTSR 963 Query: 776 --PPTLSPIPHIP-RSPYKFPSSPLRIPGGN 803 P + +P P P +P R+ G N Sbjct: 964 DSSPVMRSSSTLPVPQPSSAPPTPTRLTGAN 994 Score = 47.0 bits (110), Expect = 8e-05 Identities = 38/135 (28%), Positives = 65/135 (48%), Gaps = 27/135 (20%) Query: 744 IKEEEYDSIIVFYNSVFMQRLKTNILQY--ASTRPPTLSPIPHIPRSPYKFPSSPLRI-- 799 ++EEE +I FYN+++++++KT ++Y A+ P LSP P + SP RI Sbjct: 997 MEEEERGDLIQFYNNIYIKQIKTFAMKYSQANMDAPPLSPYPFVR------TGSPRRIQL 1050 Query: 800 -PGGNIYISPLKSPYKISEGLPTPTKMTPRSRILVSIGESFGTSEKFQKINQMVCNSDRV 858 +YISP K+ T ++PR +I S S++ ++IN M+ + Sbjct: 1051 SQNHPVYISPHKN----------ETMLSPREKIFYYFSNS--PSKRLREINSMIRTGETP 1098 Query: 859 LKRSA----EGSNPP 869 K+ +GS P Sbjct: 1099 TKKRGILLEDGSESP 1113 >gi|34577079 retinoblastoma-like protein 1 isoform a [Homo sapiens] Length = 1068 Score = 181 bits (459), Expect = 3e-45 Identities = 157/565 (27%), Positives = 257/565 (45%), Gaps = 91/565 (16%) Query: 116 TFTELQKNIEISVHKFFNLLKE-IDTST---KVDNAMSRLLKKYDVLFALFSKLERTCEL 171 + T + ++ ++S+ +FF+ +K+ +D S + + RL + ++V +F K E Sbjct: 86 SLTRILRSAKLSLIQFFSKMKKWMDMSNLPQEFRERIERLERNFEVSTVIFKKYEPIFLD 145 Query: 172 IYLTQ-------PSSSISTEINSAL--VLKVSWITFLLAKGEVLQMEDDLVISFQLMLCV 222 I+ P S I ++ + W F+ KG + DDLV S+ L+LC Sbjct: 146 IFQNPYEEPPKLPRSRKQRRIPCSVKDLFNFCWTLFVYTKGNFRMIGDDLVNSYHLLLCC 205 Query: 223 LDYFIK---LSPPM--LLKEPYKTAVIPINGSPRTPRRGQNRSARIAKQLENDTRIIEVL 277 LD + P LL +K + + T E II VL Sbjct: 206 LDLIFANAIMCPNRQDLLNPSFKGLPSDFHTADFTAS-------------EEPPCIIAVL 252 Query: 278 CKEHECNIDEVKNV---YFKNFIPFMNSLGLVTSNGLPEVEN-------LSKRYEEIYLK 327 C+ H+ + E K + YFK +I + ++ L ++ + ++K YEE L Sbjct: 253 CELHDGLLVEAKGIKEHYFKPYISKLFDRKILKGECLLDLSSFTDNSKAVNKEYEEYVLT 312 Query: 328 NKDLDARLFLDHDKTLQTDSIDSFETQRTPRKSNLDEEVNV---IPPH------------ 372 D D R+FL D + + F T+ TP L + NV + H Sbjct: 313 VGDFDERIFLGADAEEEIGTPRKF-TRDTP-LGKLTAQANVEYNLQQHFEKKRSFAPSTP 370 Query: 373 --------------TPVRTVMNTIQQLMMILNSASDQPSENLISYFNNCTVNPKESILKR 418 TPV + ++ +L I+ + PS+ LI+ F +C NP E+I+K Sbjct: 371 LTGRRYLREKEAVITPVASATQSVSRLQSIVAGLKNAPSDQLINIFESCVRNPVENIMKI 430 Query: 419 VKDIGYIFKEKFAKAVGQ---GCVEIGSQRYKLGVRLYYRVMESMLKSEEERLSIQNFSK 475 +K IG F + + ++ + ++ R KL LYY+++E+++ E RL + S Sbjct: 431 LKGIGETFCQHYTQSTDEQPGSHIDFAVNRLKLAEILYYKILETVMVQETRRLHGMDMSV 490 Query: 476 LLNDNIFHMSLLACALEVVMATYSRSTSQNLDSGTDLSFPWILNVLNLKAFDFYKVIESF 535 LL +IFH SL+AC LE+V+ YS + +FPWI+ VLNL+ F FYKVIE Sbjct: 491 LLEQDIFHRSLMACCLEIVLFAYS----------SPRTFPWIIEVLNLQPFYFYKVIEVV 540 Query: 536 IKAEGNLTREMIKHLERCEHRIMESLAWLSDSPLFDLIKQSKDREGPTDHLESACPLNLP 595 I++E L+R+M+KHL E +I+ESLAW DS L++ ++ S ++ + E P N Sbjct: 541 IRSEEGLSRDMVKHLNSIEEQILESLAWSHDSALWEALQVSANKVPTCE--EVIFPNNFE 598 Query: 596 LQNNHTAAD----MYLSPVRSPKKK 616 N M +SP+ P+ K Sbjct: 599 TGNGGNVQGHLPLMPMSPLMHPRVK 623 Score = 117 bits (292), Expect = 6e-26 Identities = 100/332 (30%), Positives = 151/332 (45%), Gaps = 70/332 (21%) Query: 594 LPLQNNHTAADMYLSPVRSPKKK---GSTTRVNSTANAETQATSAFQTQKPLKSTSLSLF 650 +PL N SPV S + N T E +T +P ++ SL+LF Sbjct: 735 IPLSMNTNQESKVKSPVSLTAHSLIGASPKQTNLTKAQEVHSTGI---NRPKRTGSLALF 791 Query: 651 YKKVYRLAYLRLNTLCERLLSEHPELEHIIWTLFQHTLQNEYELMRDRHLDQIMMCSMYG 710 Y+KVY LA +RL LC +L + EL IWT F+ TL + +LM+DRHLDQ+++C+ Y Sbjct: 792 YRKVYHLASVRLRDLCLKLDVSN-ELRRKIWTCFEFTLVHCPDLMKDRHLDQLLLCAFYI 850 Query: 711 ICKVKNIDLKFKIIVTAYKDLPHAVQETFKRVLIK------------------------- 745 + KV + F+ I+ +Y++ P A ++ VL+K Sbjct: 851 MAKVTKEERTFQEIMKSYRNQPQANSHVYRSVLLKSIPREVVAYNKNINDDFEMIDCDLE 910 Query: 746 -------------EEEYDSIIVFYNSVFMQRLKTNILQYASTR------PPTLSPIPHIP 786 +EE +I FYN++++ R+K+ L+Y P LSP PHI Sbjct: 911 DATKTPDCSSGPVKEERGDLIKFYNTIYVGRVKSFALKYDLANQDHMMDAPPLSPFPHIK 970 Query: 787 RSPYKFPSSPLRI-PGGNIYISPLKSPYKISEGLPTPTKMTPRSRILVSIGESFGTSEKF 845 + P SP RI +IYI SP+K GL TPRS +L S S+ Sbjct: 971 QQ----PGSPRRISQQHSIYI----SPHKNGSGL------TPRSALLYKFNGS--PSKSL 1014 Query: 846 QKINQMVCNSDRVLKRS--AEGSNPPKPLKKL 875 + IN M+ ++ K+ A S+ P K++ Sbjct: 1015 KDINNMIRQGEQRTKKRVIAIDSDAESPAKRV 1046 >gi|34577077 retinoblastoma-like protein 1 isoform b [Homo sapiens] Length = 1014 Score = 181 bits (459), Expect = 3e-45 Identities = 157/565 (27%), Positives = 257/565 (45%), Gaps = 91/565 (16%) Query: 116 TFTELQKNIEISVHKFFNLLKE-IDTST---KVDNAMSRLLKKYDVLFALFSKLERTCEL 171 + T + ++ ++S+ +FF+ +K+ +D S + + RL + ++V +F K E Sbjct: 86 SLTRILRSAKLSLIQFFSKMKKWMDMSNLPQEFRERIERLERNFEVSTVIFKKYEPIFLD 145 Query: 172 IYLTQ-------PSSSISTEINSAL--VLKVSWITFLLAKGEVLQMEDDLVISFQLMLCV 222 I+ P S I ++ + W F+ KG + DDLV S+ L+LC Sbjct: 146 IFQNPYEEPPKLPRSRKQRRIPCSVKDLFNFCWTLFVYTKGNFRMIGDDLVNSYHLLLCC 205 Query: 223 LDYFIK---LSPPM--LLKEPYKTAVIPINGSPRTPRRGQNRSARIAKQLENDTRIIEVL 277 LD + P LL +K + + T E II VL Sbjct: 206 LDLIFANAIMCPNRQDLLNPSFKGLPSDFHTADFTAS-------------EEPPCIIAVL 252 Query: 278 CKEHECNIDEVKNV---YFKNFIPFMNSLGLVTSNGLPEVEN-------LSKRYEEIYLK 327 C+ H+ + E K + YFK +I + ++ L ++ + ++K YEE L Sbjct: 253 CELHDGLLVEAKGIKEHYFKPYISKLFDRKILKGECLLDLSSFTDNSKAVNKEYEEYVLT 312 Query: 328 NKDLDARLFLDHDKTLQTDSIDSFETQRTPRKSNLDEEVNV---IPPH------------ 372 D D R+FL D + + F T+ TP L + NV + H Sbjct: 313 VGDFDERIFLGADAEEEIGTPRKF-TRDTP-LGKLTAQANVEYNLQQHFEKKRSFAPSTP 370 Query: 373 --------------TPVRTVMNTIQQLMMILNSASDQPSENLISYFNNCTVNPKESILKR 418 TPV + ++ +L I+ + PS+ LI+ F +C NP E+I+K Sbjct: 371 LTGRRYLREKEAVITPVASATQSVSRLQSIVAGLKNAPSDQLINIFESCVRNPVENIMKI 430 Query: 419 VKDIGYIFKEKFAKAVGQ---GCVEIGSQRYKLGVRLYYRVMESMLKSEEERLSIQNFSK 475 +K IG F + + ++ + ++ R KL LYY+++E+++ E RL + S Sbjct: 431 LKGIGETFCQHYTQSTDEQPGSHIDFAVNRLKLAEILYYKILETVMVQETRRLHGMDMSV 490 Query: 476 LLNDNIFHMSLLACALEVVMATYSRSTSQNLDSGTDLSFPWILNVLNLKAFDFYKVIESF 535 LL +IFH SL+AC LE+V+ YS + +FPWI+ VLNL+ F FYKVIE Sbjct: 491 LLEQDIFHRSLMACCLEIVLFAYS----------SPRTFPWIIEVLNLQPFYFYKVIEVV 540 Query: 536 IKAEGNLTREMIKHLERCEHRIMESLAWLSDSPLFDLIKQSKDREGPTDHLESACPLNLP 595 I++E L+R+M+KHL E +I+ESLAW DS L++ ++ S ++ + E P N Sbjct: 541 IRSEEGLSRDMVKHLNSIEEQILESLAWSHDSALWEALQVSANKVPTCE--EVIFPNNFE 598 Query: 596 LQNNHTAAD----MYLSPVRSPKKK 616 N M +SP+ P+ K Sbjct: 599 TGNGGNVQGHLPLMPMSPLMHPRVK 623 Score = 111 bits (277), Expect = 4e-24 Identities = 91/293 (31%), Positives = 133/293 (45%), Gaps = 66/293 (22%) Query: 594 LPLQNNHTAADMYLSPVRSPKKK---GSTTRVNSTANAETQATSAFQTQKPLKSTSLSLF 650 +PL N SPV S + N T E +T +P ++ SL+LF Sbjct: 735 IPLSMNTNQESKVKSPVSLTAHSLIGASPKQTNLTKAQEVHSTGI---NRPKRTGSLALF 791 Query: 651 YKKVYRLAYLRLNTLCERLLSEHPELEHIIWTLFQHTLQNEYELMRDRHLDQIMMCSMYG 710 Y+KVY LA +RL LC +L + EL IWT F+ TL + +LM+DRHLDQ+++C+ Y Sbjct: 792 YRKVYHLASVRLRDLCLKLDVSN-ELRRKIWTCFEFTLVHCPDLMKDRHLDQLLLCAFYI 850 Query: 711 ICKVKNIDLKFKIIVTAYKDLPHAVQETFKRVLIK------------------------- 745 + KV + F+ I+ +Y++ P A ++ VL+K Sbjct: 851 MAKVTKEERTFQEIMKSYRNQPQANSHVYRSVLLKSIPREVVAYNKNINDDFEMIDCDLE 910 Query: 746 -------------EEEYDSIIVFYNSVFMQRLKTNILQYASTR------PPTLSPIPHIP 786 +EE +I FYN++++ R+K+ L+Y P LSP PHI Sbjct: 911 DATKTPDCSSGPVKEERGDLIKFYNTIYVGRVKSFALKYDLANQDHMMDAPPLSPFPHIK 970 Query: 787 RSPYKFPSSPLRI-PGGNIYISPLKSPYKISEGLPTPTKMTPRSRILVSIGES 838 + P SP RI +IYI SP+K GL TPRS +L S Sbjct: 971 QQ----PGSPRRISQQHSIYI----SPHKNGSGL------TPRSALLYKFNGS 1009 >gi|55956904 mitogen-activated protein kinase kinase kinase 4 isoform a [Homo sapiens] Length = 1608 Score = 48.5 bits (114), Expect = 3e-05 Identities = 21/35 (60%), Positives = 23/35 (65%) Query: 6 PRKTAATAAAAAAEPPAPPPPPPPEEDPEQDSGPE 40 P A T AAA EPP PPPPPPP +PE +S PE Sbjct: 11 PPAFAVTPAAAMEEPPPPPPPPPPPPEPETESEPE 45 >gi|55956902 mitogen-activated protein kinase kinase kinase 4 isoform b [Homo sapiens] Length = 1558 Score = 48.5 bits (114), Expect = 3e-05 Identities = 21/35 (60%), Positives = 23/35 (65%) Query: 6 PRKTAATAAAAAAEPPAPPPPPPPEEDPEQDSGPE 40 P A T AAA EPP PPPPPPP +PE +S PE Sbjct: 11 PPAFAVTPAAAMEEPPPPPPPPPPPPEPETESEPE 45 >gi|110347459 MYC-associated zinc finger protein isoform 2 [Homo sapiens] Length = 493 Score = 41.6 bits (96), Expect = 0.003 Identities = 16/37 (43%), Positives = 20/37 (54%) Query: 3 PKTPRKTAATAAAAAAEPPAPPPPPPPEEDPEQDSGP 39 P P + AA +PPAPPPPPPP P ++ P Sbjct: 113 PPAPAAASTVDTAALKQPPAPPPPPPPVSAPAAEAAP 149 Score = 31.2 bits (69), Expect = 4.7 Identities = 19/47 (40%), Positives = 19/47 (40%), Gaps = 13/47 (27%) Query: 10 AATAAAAAAEPPAP-------------PPPPPPEEDPEQDSGPEDLP 43 AA AAA AA PPAP PP PPP P E P Sbjct: 103 AAAAAAVAAAPPAPAAASTVDTAALKQPPAPPPPPPPVSAPAAEAAP 149 >gi|110347461 MYC-associated zinc finger protein isoform 1 [Homo sapiens] Length = 477 Score = 41.6 bits (96), Expect = 0.003 Identities = 16/37 (43%), Positives = 20/37 (54%) Query: 3 PKTPRKTAATAAAAAAEPPAPPPPPPPEEDPEQDSGP 39 P P + AA +PPAPPPPPPP P ++ P Sbjct: 113 PPAPAAASTVDTAALKQPPAPPPPPPPVSAPAAEAAP 149 Score = 31.2 bits (69), Expect = 4.7 Identities = 19/47 (40%), Positives = 19/47 (40%), Gaps = 13/47 (27%) Query: 10 AATAAAAAAEPPAP-------------PPPPPPEEDPEQDSGPEDLP 43 AA AAA AA PPAP PP PPP P E P Sbjct: 103 AAAAAAVAAAPPAPAAASTVDTAALKQPPAPPPPPPPVSAPAAEAAP 149 >gi|17986273 fast skeletal myosin alkali light chain 1 isoform 1f [Homo sapiens] Length = 194 Score = 41.6 bits (96), Expect = 0.003 Identities = 21/56 (37%), Positives = 31/56 (55%), Gaps = 3/56 (5%) Query: 2 PPKTPRKTAATAAAAAAEPPAPPPPPPPEEDPEQDSGPEDLPLVRLEFEETEEPDF 57 P K +K A AAAA A PAP P P P + E+ DL +++EF + ++ +F Sbjct: 3 PKKDVKKPVAAAAAAPAPAPAPAPAPAPAKPKEEKI---DLSAIKIEFSKEQQDEF 55 >gi|56118221 amyloid beta (A4) precursor protein-binding, family B, member 1 interacting protein [Homo sapiens] Length = 666 Score = 40.8 bits (94), Expect = 0.006 Identities = 21/62 (33%), Positives = 25/62 (40%), Gaps = 4/62 (6%) Query: 3 PKTPRKTAATAAAAAAEPP----APPPPPPPEEDPEQDSGPEDLPLVRLEFEETEEPDFT 58 P TP K T PP PPPPPPP +DPE P D +F P + Sbjct: 532 PATPLKAKGTGGGGLPAPPDDFLPPPPPPPPLDDPELPPPPPDFMEPPPDFVPPPPPSYA 591 Query: 59 AL 60 + Sbjct: 592 GI 593 Score = 31.2 bits (69), Expect = 4.7 Identities = 16/37 (43%), Positives = 18/37 (48%), Gaps = 1/37 (2%) Query: 2 PPKTPRKTAATAAAAAAE-PPAPPPPPPPEEDPEQDS 37 P P + A A +E PP PPPPP P P DS Sbjct: 580 PDFVPPPPPSYAGIAGSELPPPPPPPPAPAPAPVPDS 616 >gi|25777598 diacylglycerol kinase, delta 130kDa isoform 2 [Homo sapiens] Length = 1214 Score = 40.0 bits (92), Expect = 0.010 Identities = 20/34 (58%), Positives = 20/34 (58%), Gaps = 2/34 (5%) Query: 10 AATAAAAAAEPPAPPPPPPPEEDPEQDSGPEDLP 43 AA A A PP PPPPPPPEE DS PE P Sbjct: 2 AAAAGAPPPGPPQPPPPPPPEE--SSDSEPEAEP 33 >gi|39930517 sterile alpha motif domain containing 1 [Homo sapiens] Length = 538 Score = 40.0 bits (92), Expect = 0.010 Identities = 21/42 (50%), Positives = 23/42 (54%), Gaps = 2/42 (4%) Query: 2 PPKTPRKTAATAAAAAAEPPAPPPPPPPEEDPEQDSGPEDLP 43 PP PR+ A A AA EPP PPPP PP P+Q P P Sbjct: 192 PPAGPRR-APPPAVAAREPPLPPPPQPP-APPQQQQPPPPQP 231 Score = 37.7 bits (86), Expect = 0.050 Identities = 18/42 (42%), Positives = 19/42 (45%) Query: 2 PPKTPRKTAATAAAAAAEPPAPPPPPPPEEDPEQDSGPEDLP 43 PP PR AAAAA P P P PPP P + P P Sbjct: 108 PPAPPRAPRGAPAAAAAAAPPPTPAPPPPPAPVAAAAPARAP 149 >gi|61743948 abl-interactor 1 isoform d [Homo sapiens] Length = 476 Score = 39.7 bits (91), Expect = 0.013 Identities = 20/60 (33%), Positives = 28/60 (46%), Gaps = 8/60 (13%) Query: 2 PPKTPRKT--------AATAAAAAAEPPAPPPPPPPEEDPEQDSGPEDLPLVRLEFEETE 53 PP P+ T A A+ P PPPPPPP++ P D P P +++E+ E Sbjct: 334 PPPMPQLTPQIPLTGFVARVQENIADSPTPPPPPPPDDIPMFDDSPPPPPPPPVDYEDEE 393 >gi|61743944 abl-interactor 1 isoform b [Homo sapiens] Length = 481 Score = 39.7 bits (91), Expect = 0.013 Identities = 20/60 (33%), Positives = 28/60 (46%), Gaps = 8/60 (13%) Query: 2 PPKTPRKT--------AATAAAAAAEPPAPPPPPPPEEDPEQDSGPEDLPLVRLEFEETE 53 PP P+ T A A+ P PPPPPPP++ P D P P +++E+ E Sbjct: 339 PPPMPQLTPQIPLTGFVARVQENIADSPTPPPPPPPDDIPMFDDSPPPPPPPPVDYEDEE 398 >gi|61743942 abl-interactor 1 isoform a [Homo sapiens] Length = 508 Score = 39.7 bits (91), Expect = 0.013 Identities = 20/60 (33%), Positives = 28/60 (46%), Gaps = 8/60 (13%) Query: 2 PPKTPRKT--------AATAAAAAAEPPAPPPPPPPEEDPEQDSGPEDLPLVRLEFEETE 53 PP P+ T A A+ P PPPPPPP++ P D P P +++E+ E Sbjct: 366 PPPMPQLTPQIPLTGFVARVQENIADSPTPPPPPPPDDIPMFDDSPPPPPPPPVDYEDEE 425 >gi|4507909 Wiskott-Aldrich syndrome protein [Homo sapiens] Length = 502 Score = 39.3 bits (90), Expect = 0.017 Identities = 19/48 (39%), Positives = 21/48 (43%), Gaps = 5/48 (10%) Query: 2 PPKTPRKTAATAAA-----AAAEPPAPPPPPPPEEDPEQDSGPEDLPL 44 PP P T + A PP PPPPPPP P +GP PL Sbjct: 368 PPPPPPATGRSGPLPPPPPGAGGPPMPPPPPPPPPPPSSGNGPAPPPL 415 >gi|122937496 WAS/WASL interacting protein family, member 3 [Homo sapiens] Length = 483 Score = 39.3 bits (90), Expect = 0.017 Identities = 22/57 (38%), Positives = 25/57 (43%), Gaps = 12/57 (21%) Query: 1 MPPKTPRKTAATAAAAAAE------------PPAPPPPPPPEEDPEQDSGPEDLPLV 45 +PP +PR + A AA PP PPPPPPP P S P PLV Sbjct: 145 IPPASPRLGNTSEAHGAARTAPPRPNVPAPPPPTPPPPPPPLPPPLPSSSPIKTPLV 201 Score = 32.0 bits (71), Expect = 2.7 Identities = 13/31 (41%), Positives = 13/31 (41%) Query: 3 PKTPRKTAATAAAAAAEPPAPPPPPPPEEDP 33 P T A PP PPPPPPP P Sbjct: 206 PLTKGNLPVVAPPVPCAPPPPPPPPPPTPPP 236 Score = 31.6 bits (70), Expect = 3.6 Identities = 13/19 (68%), Positives = 14/19 (73%) Query: 11 ATAAAAAAEPPAPPPPPPP 29 A+ A A EPPAPPPP PP Sbjct: 280 ASPAQDAQEPPAPPPPLPP 298 >gi|33188449 serine/arginine-rich protein-specific kinase 2 isoform a [Homo sapiens] Length = 699 Score = 38.9 bits (89), Expect = 0.022 Identities = 18/52 (34%), Positives = 25/52 (48%) Query: 4 KTPRKTAATAAAAAAEPPAPPPPPPPEEDPEQDSGPEDLPLVRLEFEETEEP 55 K P+K A PP PPPPPPP P+ + ++ + EE E+P Sbjct: 20 KHPKKPEPQQKAPLVPPPPPPPPPPPPPLPDPTPPEPEEEILGSDDEEQEDP 71 Score = 32.3 bits (72), Expect = 2.1 Identities = 15/42 (35%), Positives = 20/42 (47%) Query: 21 PAPPPPPPPEEDPEQDSGPEDLPLVRLEFEETEEPDFTALCQ 62 P PPPPPPP P D P + L ++ E+ D C+ Sbjct: 35 PPPPPPPPPPPPPLPDPTPPEPEEEILGSDDEEQEDPADYCK 76 >gi|61743946 abl-interactor 1 isoform c [Homo sapiens] Length = 452 Score = 38.9 bits (89), Expect = 0.022 Identities = 15/36 (41%), Positives = 22/36 (61%) Query: 18 AEPPAPPPPPPPEEDPEQDSGPEDLPLVRLEFEETE 53 A+ P PPPPPPP++ P D P P +++E+ E Sbjct: 334 ADSPTPPPPPPPDDIPMFDDSPPPPPPPPVDYEDEE 369 >gi|126090663 zinc finger homeodomain 4 [Homo sapiens] Length = 3571 Score = 38.9 bits (89), Expect = 0.022 Identities = 18/46 (39%), Positives = 20/46 (43%) Query: 2 PPKTPRKTAATAAAAAAEPPAPPPPPPPEEDPEQDSGPEDLPLVRL 47 P K P + A PP PPPPPPP P P P V+L Sbjct: 1979 PVKIPNTVSTPLQAPPPTPPPPPPPPPPPPPPPPPPPPSAPPQVQL 2024 Score = 34.3 bits (77), Expect = 0.55 Identities = 20/45 (44%), Positives = 20/45 (44%), Gaps = 7/45 (15%) Query: 2 PPKTPRKTAATAAAAAAEPPAPPPPPPPEEDPEQDSGPE--DLPL 44 PP TP PP PPPPPPP P Q P DLPL Sbjct: 1993 PPPTP-----PPPPPPPPPPPPPPPPPPPSAPPQVQLPVSLDLPL 2032 Score = 31.2 bits (69), Expect = 4.7 Identities = 24/88 (27%), Positives = 36/88 (40%), Gaps = 4/88 (4%) Query: 3 PKTPRKTAATAAAAAAEPPAPPPPPPPEEDPEQDSGPEDLPLVRLEFEETE-EPDFTALC 61 P +A T PP PPPPPPP P + E E+ + +P+ Sbjct: 3101 PALSLSSAPTKPLLQTPPPPPPPPPPP---PSSSLSGQQTEQQNKESEKKQTKPNKVKKI 3157 Query: 62 QKLKIPDHVRERAWLTWEKVSSVDGVLG 89 ++ ++ E+ EK+SS VLG Sbjct: 3158 KEEELEATKPEKHPKKEEKISSALSVLG 3185 Score = 30.8 bits (68), Expect = 6.1 Identities = 14/26 (53%), Positives = 15/26 (57%), Gaps = 2/26 (7%) Query: 20 PPAPPPPPPPEEDPEQDS--GPEDLP 43 PP PPPPPP P Q S GP +P Sbjct: 1958 PPPPPPPPPLPPAPPQPSSMGPVKIP 1983 >gi|117938310 sine oculis binding protein homolog [Homo sapiens] Length = 873 Score = 38.9 bits (89), Expect = 0.022 Identities = 22/55 (40%), Positives = 29/55 (52%), Gaps = 2/55 (3%) Query: 7 RKTAATAAAAAAEPPAPPPPPPPEEDPEQDSGPEDLPLVRLEFEETEEPDFTALC 61 R AA A +A PP PPPPPP P++ PE+ P V E E +E + + C Sbjct: 728 RGAAAEGAKSAEPPPEQPPPPPPPAPPKKLLSPEE-PAVS-ELESVKENNCASNC 780 >gi|46048439 N-acetyltransferase 6 [Homo sapiens] Length = 308 Score = 38.5 bits (88), Expect = 0.029 Identities = 20/52 (38%), Positives = 24/52 (46%), Gaps = 3/52 (5%) Query: 2 PPKTPRKTAATAAAAAAEPPAPPPPPPPE---EDPEQDSGPEDLPLVRLEFE 50 P K P TA A PP PPPPP PE P SGP L+ +++ Sbjct: 243 PRKAPNLTAQAAPRGPKGPPLPPPPPLPECLTISPPVPSGPPSKSLLETQYQ 294 >gi|148229134 ring finger and KH domain containing 2 [Homo sapiens] Length = 659 Score = 38.5 bits (88), Expect = 0.029 Identities = 18/40 (45%), Positives = 19/40 (47%) Query: 1 MPPKTPRKTAATAAAAAAEPPAPPPPPPPEEDPEQDSGPE 40 MP + A AA A P PPPPPPP P GPE Sbjct: 1 MPSGSSAALALAAAPAPLPQPPPPPPPPPPPLPPPSGGPE 40 >gi|195947369 junction-mediating and regulatory protein [Homo sapiens] Length = 988 Score = 38.1 bits (87), Expect = 0.038 Identities = 20/38 (52%), Positives = 21/38 (55%), Gaps = 2/38 (5%) Query: 20 PPAPPPPPPPEEDPEQDSGPEDL--PLVRLEFEETEEP 55 PP PPPPPPP +DSGPE L L R E E P Sbjct: 815 PPPPPPPPPPPLPVAKDSGPETLEKDLPRKEGNEKRIP 852 >gi|156523246 proline-rich transmembrane protein 2 [Homo sapiens] Length = 340 Score = 38.1 bits (87), Expect = 0.038 Identities = 16/39 (41%), Positives = 21/39 (53%) Query: 17 AAEPPAPPPPPPPEEDPEQDSGPEDLPLVRLEFEETEEP 55 +A PP P P P P+ DP DS P P ++ E E+P Sbjct: 128 SAAPPEPAPEPAPQPDPRPDSQPTPKPALQPELPTQEDP 166 >gi|164698460 mannosidase, endo-alpha-like isoform 3 [Homo sapiens] Length = 457 Score = 38.1 bits (87), Expect = 0.038 Identities = 19/38 (50%), Positives = 20/38 (52%), Gaps = 2/38 (5%) Query: 4 KTPRKTAATAAAAAAEPPAPPPPPPPEE--DPEQDSGP 39 + P A AA A A P APPPPPPP DP GP Sbjct: 49 RRPEGAPAPAARAPAAPAAPPPPPPPPRTADPGGSPGP 86 >gi|72534766 mannosidase, endo-alpha-like isoform 1 [Homo sapiens] Length = 250 Score = 38.1 bits (87), Expect = 0.038 Identities = 19/38 (50%), Positives = 20/38 (52%), Gaps = 2/38 (5%) Query: 4 KTPRKTAATAAAAAAEPPAPPPPPPPEE--DPEQDSGP 39 + P A AA A A P APPPPPPP DP GP Sbjct: 49 RRPEGAPAPAARAPAAPAAPPPPPPPPRTADPGGSPGP 86 >gi|158534059 formin binding protein 4 [Homo sapiens] Length = 1017 Score = 37.7 bits (86), Expect = 0.050 Identities = 20/55 (36%), Positives = 25/55 (45%), Gaps = 7/55 (12%) Query: 1 MPPKTPRKTAATAAAAAAEPPAPPPPPPPEEDPEQDSGPEDLPLVRLEFEETEEP 55 + P P + PP PPPPPPP ED E + V +E E +EEP Sbjct: 703 LQPPLPLEMPPPPPPPPESPPPPPPPPPPAEDGE-------IQEVEMEDEGSEEP 750 Score = 34.7 bits (78), Expect = 0.42 Identities = 14/31 (45%), Positives = 15/31 (48%) Query: 11 ATAAAAAAEPPAPPPPPPPEEDPEQDSGPED 41 A A EPP PPPPPPP P P + Sbjct: 896 AVPTATIIEPPPPPPPPPPPPPPAPKMPPPE 926 Score = 33.9 bits (76), Expect = 0.72 Identities = 14/34 (41%), Positives = 16/34 (47%) Query: 1 MPPKTPRKTAATAAAAAAEPPAPPPPPPPEEDPE 34 + P R TA PP PPPPPPP P+ Sbjct: 888 LQPVQARGAVPTATIIEPPPPPPPPPPPPPPAPK 921 Score = 32.7 bits (73), Expect = 1.6 Identities = 19/57 (33%), Positives = 23/57 (40%), Gaps = 3/57 (5%) Query: 3 PKTPRKTAATAAAAAAEPPAP---PPPPPPEEDPEQDSGPEDLPLVRLEFEETEEPD 56 P TP T + +PP P PPPPPP + P P E +E E D Sbjct: 688 PLTPFWTLLQSNVPVLQPPLPLEMPPPPPPPPESPPPPPPPPPPAEDGEIQEVEMED 744 Score = 30.8 bits (68), Expect = 6.1 Identities = 16/54 (29%), Positives = 22/54 (40%) Query: 10 AATAAAAAAEPPAPPPPPPPEEDPEQDSGPEDLPLVRLEFEETEEPDFTALCQK 63 A A PP PPPPPPP + PE R + + + +L +K Sbjct: 896 AVPTATIIEPPPPPPPPPPPPPPAPKMPPPEKTKKGRKDKAKKSKTKMPSLVKK 949 >gi|149944526 additional sex combs like 3 [Homo sapiens] Length = 2248 Score = 37.7 bits (86), Expect = 0.050 Identities = 19/64 (29%), Positives = 25/64 (39%) Query: 2 PPKTPRKTAATAAAAAAEPPAPPPPPPPEEDPEQDSGPEDLPLVRLEFEETEEPDFTALC 61 PP P A PP PPP PPP + E S + P+ + P T +C Sbjct: 2017 PPPPPPPPPPPPLALPPPPPPPPPLPPPLPNAEVPSDQKQPPVTMETTKRLSWPQSTGIC 2076 Query: 62 QKLK 65 +K Sbjct: 2077 SNIK 2080 Score = 32.7 bits (73), Expect = 1.6 Identities = 19/49 (38%), Positives = 20/49 (40%), Gaps = 6/49 (12%) Query: 1 MPPKTPRKTAATA------AAAAAEPPAPPPPPPPEEDPEQDSGPEDLP 43 MP K + TA A PP PPPPPPP P P LP Sbjct: 1994 MPMKEGDEVGGTAHTMPNKALVHPPPPPPPPPPPPLALPPPPPPPPPLP 2042 >gi|5730045 solute carrier family 16, member 2 [Homo sapiens] Length = 613 Score = 37.4 bits (85), Expect = 0.065 Identities = 19/40 (47%), Positives = 21/40 (52%), Gaps = 2/40 (5%) Query: 21 PAPPPPPPPEEDPEQDSGPEDLPLVRLEF--EETEEPDFT 58 P P P PPPE PE P+ PL LEF E EP+ T Sbjct: 115 PEPVPVPPPEPQPEPQPLPDPAPLPELEFESERVHEPEPT 154 Database: hs.faa Posted date: Aug 4, 2009 4:42 PM Number of letters in database: 18,247,518 Number of sequences in database: 37,866 Lambda K H 0.317 0.133 0.384 Gapped Lambda K H 0.267 0.0410 0.140 Matrix: BLOSUM62 Gap Penalties: Existence: 11, Extension: 1 Number of Hits to DB: 36,977,388 Number of Sequences: 37866 Number of extensions: 1817218 Number of successful extensions: 26838 Number of sequences better than 10.0: 30 Number of HSP's better than 10.0 without gapping: 289 Number of HSP's successfully gapped in prelim test: 117 Number of HSP's that attempted gapping in prelim test: 19975 Number of HSP's gapped (non-prelim): 4769 length of query: 928 length of database: 18,247,518 effective HSP length: 112 effective length of query: 816 effective length of database: 14,006,526 effective search space: 11429325216 effective search space used: 11429325216 T: 11 A: 40 X1: 16 ( 7.3 bits) X2: 38 (14.6 bits) X3: 64 (24.7 bits) S1: 41 (21.7 bits) S2: 67 (30.4 bits)
Search results were obtained with NCBI BLAST and RefSeq entries.
Guide to the Human Genome
Copyright © 2010 by Stewart Scherer. All rights reserved.