Guide to the Human Genome
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Name: MAP3K4 Sequence: fasta or formatted (1558aa) NCBI GI: 55956902
Description:

mitogen-activated protein kinase kinase kinase 4 isoform b

Referenced in:

MAP Kinase Pathways
p53 Pathway

Other entries for this name:
alt prot [1608aa] mitogen-activated protein kinase kinase kinase 4 isoform a
Composition:

amino acid map
 Amino acid        Percentage    Count  Longest homopolymer
 A alanine             6.2         97           4
 C cysteine            1.9         30           2
 D aspartate           5.6         88           2
 E glutamate           8.9        139           3
 F phenylalanine       3.7         58           2
 G glycine             5.5         85           2
 H histidine           2.4         38           2
 I isoleucine          5.2         81           2
 K lysine              6.5        102           3
 L leucine             9.8        152           3
 M methionine          2.8         43           1
 N asparagine          3.2         50           2
 P proline             6.0         93          12
 Q glutamine           4.7         73           2
 R arginine            6.2         97           2
 S serine              7.7        120           2
 T threonine           4.5         70           2
 V valine              5.2         81           2
 W tryptophan          1.3         21           1
 Y tyrosine            2.6         40           2
Comparative genomics:

Search single species RefSeq proteins at NCBI
   H. sapiens
   M. musculus
   D. rerio
   C. intestinalis
   S. purpuratus
   D. melanogaster
   C. elegans
   A. thaliana
   S. cerevisiae
   E. coli W3110
   A. pernix K1

Search summary

comparative genomics plot

   Figure data

Additional searches of
RefSeq proteins at NCBI

   All
   Eukaryotes
   Bacteria
   Archaea
   Viruses
   Primates
   Mammals
   Vertebrates

Related human proteins:
Protein          Relative score         Description

Self-match            1.000   mitogen-activated protein kinase kinase kinase 4 iso... 
MAP3K4                0.992   mitogen-activated protein kinase kinase kinase 4 iso...
MAP3K3                0.055   mitogen-activated protein kinase kinase kinase 3 iso...
MAP3K3                0.055   mitogen-activated protein kinase kinase kinase 3 iso...
MAP3K2                0.052   mitogen-activated protein kinase kinase kinase 2 [Ho...
YSK4                  0.047   Yeast Sps1/Ste20-related kinase 4 isoform 1 
YSK4                  0.047   Yeast Sps1/Ste20-related kinase 4 isoform 2 
MAP3K5                0.044   mitogen-activated protein kinase kinase kinase 5 [Hom...
MAP3K15               0.044   mitogen-activated protein kinase kinase kinase 15 [...
MAP3K1                0.044   mitogen-activated protein kinase kinase kinase 1 [H...
MAP3K6                0.043   mitogen-activated protein kinase kinase kinase 6 [Ho...
PAK3                  0.042   p21-activated kinase 3 isoform d 
PAK3                  0.042   p21-activated kinase 3 isoform c 
PAK3                  0.042   p21-activated kinase 3 isoform b 
PAK3                  0.042   p21-activated kinase 3 isoform a 
PAK3                  0.042   p21-activated kinase 3 isoform a 
PAK3                  0.042   p21-activated kinase 3 isoform a 
SLK                   0.042   serine/threonine kinase 2 
PAK1                  0.041   p21-activated kinase 1 isoform 2 
PAK2                  0.041   p21-activated kinase 2 
STK10                 0.040   serine/threonine kinase 10 
STK4                  0.040   serine/threonine kinase 4 
MAP4K3                0.039   mitogen-activated protein kinase kinase kinase kinas...
STK3                  0.039   serine/threonine kinase 3 
PAK1                  0.038   p21-activated kinase 1 isoform 1 
MAP4K5                0.038   mitogen-activated protein kinase kinase kinase kinas...
MAP4K5                0.038   mitogen-activated protein kinase kinase kinase kinas...
STK25                 0.036   serine/threonine kinase 25 
CDKL1                 0.036   cyclin-dependent kinase-like 1 
MAP4K2                0.036   mitogen-activated protein kinase kinase kinase kinas...
Human BLASTP results (used to prepare the table)

Gene descriptions are from NCBI RefSeq. Search results were obtained with NCBI BLAST and RefSeq entries. When identical proteins are present, the self-match may not be listed first in BLASTP output. In such cases, the table above has been reordered to place it first.

See About the Figures for the scoring system used in the figure above right. The same scoring system was used in the table of BLASTP results.


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Guide to the Human Genome
Copyright © 2010 by Stewart Scherer. All rights reserved.

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