Guide to the Human Genome
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Search of human proteins with 4557757

BLASTP 2.2.11 [Jun-05-2005]


Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer, 
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), 
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs",  Nucleic Acids Res. 25:3389-3402.

Query= gi|4557757 MutL protein homolog 1 [Homo sapiens]
         (756 letters)

Database: hs.faa 
           37,866 sequences; 18,247,518 total letters

Searching..................................................done

                                                                 Score    E
Sequences producing significant alignments:                      (bits) Value

gi|4557757 MutL protein homolog 1 [Homo sapiens]                     1494   0.0  
gi|4505913 PMS2 postmeiotic segregation increased 2 isoform a [H...   167   4e-41
gi|189458898 postmeiotic segregation 1 isoform c [Homo sapiens]       131   3e-30
gi|4505911 postmeiotic segregation 1 isoform a [Homo sapiens]         131   3e-30
gi|189458896 postmeiotic segregation 1 isoform b [Homo sapiens]       121   2e-27
gi|91992162 mutL homolog 3 isoform 1 [Homo sapiens]                   110   4e-24
gi|91992160 mutL homolog 3 isoform 2 [Homo sapiens]                   110   4e-24
gi|239743246 PREDICTED: hypothetical protein XP_002342778 [Homo ...    98   3e-20
gi|169170512 PREDICTED: similar to Postmeiotic segregation incre...    98   3e-20
gi|19923559 EMSY protein [Homo sapiens]                                37   0.089
gi|50843827 activating molecule in beclin-1-regulated autophagy ...    36   0.15 
gi|7019405 host cell factor C2 [Homo sapiens]                          36   0.15 
gi|5454016 retinitis pigmentosa RP1 protein [Homo sapiens]             35   0.34 
gi|13376367 WD repeat domain 76 [Homo sapiens]                         35   0.34 
gi|22538422 activating transcription factor 2 [Homo sapiens]           34   0.57 
gi|82830424 gon-4-like isoform a [Homo sapiens]                        33   0.75 
gi|217035133 hypothetical protein LOC55765 isoform 2 [Homo sapiens]    33   0.75 
gi|217035131 hypothetical protein LOC55765 isoform 1 [Homo sapiens]    33   0.75 
gi|83415174 hypothetical protein LOC400818 [Homo sapiens]              33   0.75 
gi|27262628 nuclear autoantigenic sperm protein isoform 2 [Homo ...    33   0.98 
gi|27262634 nuclear autoantigenic sperm protein isoform 1 [Homo ...    33   0.98 
gi|11067749 bromodomain containing protein 3 [Homo sapiens]            33   0.98 
gi|82830428 gon-4-like isoform b [Homo sapiens]                        33   1.3  
gi|41352705 kinesin family member 3C [Homo sapiens]                    33   1.3  
gi|118572613 splicing coactivator subunit SRm300 [Homo sapiens]        33   1.3  
gi|5174573 myeloid/lymphoid or mixed-lineage leukemia trithorax ...    32   1.7  
gi|114158664 hypothetical protein LOC343505 [Homo sapiens]             32   1.7  
gi|190014588 PC4 and SFRS1 interacting protein 1 isoform 2 [Homo...    32   2.2  
gi|190014586 PC4 and SFRS1 interacting protein 1 isoform 1 [Homo...    32   2.2  
gi|19923653 PC4 and SFRS1 interacting protein 1 isoform 2 [Homo ...    32   2.2  

>gi|4557757 MutL protein homolog 1 [Homo sapiens]
          Length = 756

 Score = 1494 bits (3869), Expect = 0.0
 Identities = 756/756 (100%), Positives = 756/756 (100%)

Query: 1   MSFVAGVIRRLDETVVNRIAAGEVIQRPANAIKEMIENCLDAKSTSIQVIVKEGGLKLIQ 60
           MSFVAGVIRRLDETVVNRIAAGEVIQRPANAIKEMIENCLDAKSTSIQVIVKEGGLKLIQ
Sbjct: 1   MSFVAGVIRRLDETVVNRIAAGEVIQRPANAIKEMIENCLDAKSTSIQVIVKEGGLKLIQ 60

Query: 61  IQDNGTGIRKEDLDIVCERFTTSKLQSFEDLASISTYGFRGEALASISHVAHVTITTKTA 120
           IQDNGTGIRKEDLDIVCERFTTSKLQSFEDLASISTYGFRGEALASISHVAHVTITTKTA
Sbjct: 61  IQDNGTGIRKEDLDIVCERFTTSKLQSFEDLASISTYGFRGEALASISHVAHVTITTKTA 120

Query: 121 DGKCAYRASYSDGKLKAPPKPCAGNQGTQITVEDLFYNIATRRKALKNPSEEYGKILEVV 180
           DGKCAYRASYSDGKLKAPPKPCAGNQGTQITVEDLFYNIATRRKALKNPSEEYGKILEVV
Sbjct: 121 DGKCAYRASYSDGKLKAPPKPCAGNQGTQITVEDLFYNIATRRKALKNPSEEYGKILEVV 180

Query: 181 GRYSVHNAGISFSVKKQGETVADVRTLPNASTVDNIRSIFGNAVSRELIEIGCEDKTLAF 240
           GRYSVHNAGISFSVKKQGETVADVRTLPNASTVDNIRSIFGNAVSRELIEIGCEDKTLAF
Sbjct: 181 GRYSVHNAGISFSVKKQGETVADVRTLPNASTVDNIRSIFGNAVSRELIEIGCEDKTLAF 240

Query: 241 KMNGYISNANYSVKKCIFLLFINHRLVESTSLRKAIETVYAAYLPKNTHPFLYLSLEISP 300
           KMNGYISNANYSVKKCIFLLFINHRLVESTSLRKAIETVYAAYLPKNTHPFLYLSLEISP
Sbjct: 241 KMNGYISNANYSVKKCIFLLFINHRLVESTSLRKAIETVYAAYLPKNTHPFLYLSLEISP 300

Query: 301 QNVDVNVHPTKHEVHFLHEESILERVQQHIESKLLGSNSSRMYFTQTLLPGLAGPSGEMV 360
           QNVDVNVHPTKHEVHFLHEESILERVQQHIESKLLGSNSSRMYFTQTLLPGLAGPSGEMV
Sbjct: 301 QNVDVNVHPTKHEVHFLHEESILERVQQHIESKLLGSNSSRMYFTQTLLPGLAGPSGEMV 360

Query: 361 KSTTSLTSSSTSGSSDKVYAHQMVRTDSREQKLDAFLQPLSKPLSSQPQAIVTEDKTDIS 420
           KSTTSLTSSSTSGSSDKVYAHQMVRTDSREQKLDAFLQPLSKPLSSQPQAIVTEDKTDIS
Sbjct: 361 KSTTSLTSSSTSGSSDKVYAHQMVRTDSREQKLDAFLQPLSKPLSSQPQAIVTEDKTDIS 420

Query: 421 SGRARQQDEEMLELPAPAEVAAKNQSLEGDTTKGTSEMSEKRGPTSSNPRKRHREDSDVE 480
           SGRARQQDEEMLELPAPAEVAAKNQSLEGDTTKGTSEMSEKRGPTSSNPRKRHREDSDVE
Sbjct: 421 SGRARQQDEEMLELPAPAEVAAKNQSLEGDTTKGTSEMSEKRGPTSSNPRKRHREDSDVE 480

Query: 481 MVEDDSRKEMTAACTPRRRIINLTSVLSLQEEINEQGHEVLREMLHNHSFVGCVNPQWAL 540
           MVEDDSRKEMTAACTPRRRIINLTSVLSLQEEINEQGHEVLREMLHNHSFVGCVNPQWAL
Sbjct: 481 MVEDDSRKEMTAACTPRRRIINLTSVLSLQEEINEQGHEVLREMLHNHSFVGCVNPQWAL 540

Query: 541 AQHQTKLYLLNTTKLSEELFYQILIYDFANFGVLRLSEPAPLFDLAMLALDSPESGWTEE 600
           AQHQTKLYLLNTTKLSEELFYQILIYDFANFGVLRLSEPAPLFDLAMLALDSPESGWTEE
Sbjct: 541 AQHQTKLYLLNTTKLSEELFYQILIYDFANFGVLRLSEPAPLFDLAMLALDSPESGWTEE 600

Query: 601 DGPKEGLAEYIVEFLKKKAEMLADYFSLEIDEEGNLIGLPLLIDNYVPPLEGLPIFILRL 660
           DGPKEGLAEYIVEFLKKKAEMLADYFSLEIDEEGNLIGLPLLIDNYVPPLEGLPIFILRL
Sbjct: 601 DGPKEGLAEYIVEFLKKKAEMLADYFSLEIDEEGNLIGLPLLIDNYVPPLEGLPIFILRL 660

Query: 661 ATEVNWDEEKECFESLSKECAMFYSIRKQYISEESTLSGQQSEVPGSIPNSWKWTVEHIV 720
           ATEVNWDEEKECFESLSKECAMFYSIRKQYISEESTLSGQQSEVPGSIPNSWKWTVEHIV
Sbjct: 661 ATEVNWDEEKECFESLSKECAMFYSIRKQYISEESTLSGQQSEVPGSIPNSWKWTVEHIV 720

Query: 721 YKALRSHILPPKHFTEDGNILQLANLPDLYKVFERC 756
           YKALRSHILPPKHFTEDGNILQLANLPDLYKVFERC
Sbjct: 721 YKALRSHILPPKHFTEDGNILQLANLPDLYKVFERC 756


>gi|4505913 PMS2 postmeiotic segregation increased 2 isoform a [Homo
           sapiens]
          Length = 862

 Score =  167 bits (422), Expect = 4e-41
 Identities = 119/384 (30%), Positives = 205/384 (53%), Gaps = 36/384 (9%)

Query: 5   AGVIRRLDETVVNRIAAGEVIQRPANAIKEMIENCLDAKSTSIQVIVKEGGLKLIQIQDN 64
           A  I+ +D   V++I +G+V+   + A+KE++EN LDA +T+I + +K+ G+ LI++ DN
Sbjct: 12  AKAIKPIDRKSVHQICSGQVVLSLSTAVKELVENSLDAGATNIDLKLKDYGVDLIEVSDN 71

Query: 65  GTGIRKEDLDIVCERFTTSKLQSFEDLASISTYGFRGEALASISHVAHVTITTKTADGKC 124
           G G+ +E+ + +  +  TSK+Q F DL  + T+GFRGEAL+S+  ++ VTI+T  A  K 
Sbjct: 72  GCGVEEENFEGLTLKHHTSKIQEFADLTQVETFGFRGEALSSLCALSDVTISTCHASAKV 131

Query: 125 AYRASYS-DGKL--KAP-PKPCAGNQGTQITVEDLFYNIATRRKAL-KNPSEEYGKILEV 179
             R  +  +GK+  K P P+P    +GT ++V+ LF  +  R K   +N  +EY K+++V
Sbjct: 132 GTRLMFDHNGKIIQKTPYPRP----RGTTVSVQQLFSTLPVRHKEFQRNIKKEYAKMVQV 187

Query: 180 VGRYSVHNAGISFSVKK---QGETVADVRTLPNASTVDNIRSIFGNAVSRELI------- 229
           +  Y + +AGI  S      QG+    V T  + S  +NI S+FG    + LI       
Sbjct: 188 LHAYCIISAGIRVSCTNQLGQGKRQPVVCTGGSPSIKENIGSVFGQKQLQSLIPFVQLPP 247

Query: 230 -EIGCEDKTLA--------FKMNGYISNANYSVKKCIF---LLFINHRLVESTSLRKAIE 277
            +  CE+  L+        F ++G+IS   + V +        FIN R  +   + + + 
Sbjct: 248 SDSVCEEYGLSCSDALHNLFYISGFISQCTHGVGRSSTDRQFFFINRRPCDPAKVCRLVN 307

Query: 278 TVYAAYLPKNTHPFLYLSLEISPQNVDVNVHPTKHEVHFLHEESILERVQQHIESKLLGS 337
            VY  Y  ++ +PF+ L++ +  + VD+NV P K ++  L EE +L  V   +++ L+G 
Sbjct: 308 EVYHMY-NRHQYPFVVLNISVDSECVDINVTPDKRQI-LLQEEKLLLAV---LKTSLIGM 362

Query: 338 NSSRMYFTQTLLPGLAGPSGEMVK 361
             S +         L    G ++K
Sbjct: 363 FDSDVNKLNVSQQPLLDVEGNLIK 386


>gi|189458898 postmeiotic segregation 1 isoform c [Homo sapiens]
          Length = 770

 Score =  131 bits (329), Expect = 3e-30
 Identities = 92/332 (27%), Positives = 162/332 (48%), Gaps = 22/332 (6%)

Query: 8   IRRLDETVVNRIAAGEVIQRPANAIKEMIENCLDAKSTSIQVIVKEGGLKLIQIQDNGTG 67
           +++L    V  +++ ++I    + +KE+IEN LDA +TS+ V ++  G   I+++DNG G
Sbjct: 1   MKQLPAATVRLLSSSQIITSVVSVVKELIENSLDAGATSVDVKLENYGFDKIEVRDNGEG 60

Query: 68  IRKEDLDIVCERFTTSKLQSFEDLASISTYGFRGEALASISHVAHVTITTKTADGKCAYR 127
           I+  D  ++  ++ TSK+ S EDL +++TYGFRGEAL SI  +A V ITT+TA    + +
Sbjct: 61  IKAVDAPVMAMKYYTSKINSHEDLENLTTYGFRGEALGSICCIAEVLITTRTAADNFSTQ 120

Query: 128 ASYSDGKLKAPPKPCAGNQGTQITVEDLFYNIATRRK---ALKNPSEEYGKILEVVGRYS 184
                       KP    QGT +T   LF N+  R++     K   +E  KI +++  + 
Sbjct: 121 YVLDGSGHILSQKPSHLGQGTTVTALRLFKNLPVRKQFYSTAKKCKDEIKKIQDLLMSFG 180

Query: 185 ----------VHNAGISFSVKKQGETVADVRTLPNASTVDNIRSIFGNAVSRELIEIGCE 234
                     VHN  + +   +  +    + ++   + ++N+ S   ++   ++   G  
Sbjct: 181 ILKPDLRIVFVHNKAVIWQKSRVSDHKMALMSVLGTAVMNNMESFQYHSEESQIYLSGFL 240

Query: 235 DKTLAFKMNGYISNANYSVKKCIFLLFINHRLVESTSLRKAIETVYAAYLPKNT---HPF 291
            K  A      +S    S       +FIN R V    + K I   Y     K +   +P 
Sbjct: 241 PKCDADHSFTSLSTPERS------FIFINSRPVHQKDILKLIRHHYNLKCLKESTRLYPV 294

Query: 292 LYLSLEISPQNVDVNVHPTKHEVHFLHEESIL 323
            +L +++   +VDVN+ P K +V   ++ES+L
Sbjct: 295 FFLKIDVPTADVDVNLTPDKSQVLLQNKESVL 326


>gi|4505911 postmeiotic segregation 1 isoform a [Homo sapiens]
          Length = 932

 Score =  131 bits (329), Expect = 3e-30
 Identities = 92/332 (27%), Positives = 162/332 (48%), Gaps = 22/332 (6%)

Query: 8   IRRLDETVVNRIAAGEVIQRPANAIKEMIENCLDAKSTSIQVIVKEGGLKLIQIQDNGTG 67
           +++L    V  +++ ++I    + +KE+IEN LDA +TS+ V ++  G   I+++DNG G
Sbjct: 1   MKQLPAATVRLLSSSQIITSVVSVVKELIENSLDAGATSVDVKLENYGFDKIEVRDNGEG 60

Query: 68  IRKEDLDIVCERFTTSKLQSFEDLASISTYGFRGEALASISHVAHVTITTKTADGKCAYR 127
           I+  D  ++  ++ TSK+ S EDL +++TYGFRGEAL SI  +A V ITT+TA    + +
Sbjct: 61  IKAVDAPVMAMKYYTSKINSHEDLENLTTYGFRGEALGSICCIAEVLITTRTAADNFSTQ 120

Query: 128 ASYSDGKLKAPPKPCAGNQGTQITVEDLFYNIATRRK---ALKNPSEEYGKILEVVGRYS 184
                       KP    QGT +T   LF N+  R++     K   +E  KI +++  + 
Sbjct: 121 YVLDGSGHILSQKPSHLGQGTTVTALRLFKNLPVRKQFYSTAKKCKDEIKKIQDLLMSFG 180

Query: 185 ----------VHNAGISFSVKKQGETVADVRTLPNASTVDNIRSIFGNAVSRELIEIGCE 234
                     VHN  + +   +  +    + ++   + ++N+ S   ++   ++   G  
Sbjct: 181 ILKPDLRIVFVHNKAVIWQKSRVSDHKMALMSVLGTAVMNNMESFQYHSEESQIYLSGFL 240

Query: 235 DKTLAFKMNGYISNANYSVKKCIFLLFINHRLVESTSLRKAIETVYAAYLPKNT---HPF 291
            K  A      +S    S       +FIN R V    + K I   Y     K +   +P 
Sbjct: 241 PKCDADHSFTSLSTPERS------FIFINSRPVHQKDILKLIRHHYNLKCLKESTRLYPV 294

Query: 292 LYLSLEISPQNVDVNVHPTKHEVHFLHEESIL 323
            +L +++   +VDVN+ P K +V   ++ES+L
Sbjct: 295 FFLKIDVPTADVDVNLTPDKSQVLLQNKESVL 326


>gi|189458896 postmeiotic segregation 1 isoform b [Homo sapiens]
          Length = 893

 Score =  121 bits (304), Expect = 2e-27
 Identities = 93/322 (28%), Positives = 154/322 (47%), Gaps = 41/322 (12%)

Query: 8   IRRLDETVVNRIAAGEVIQRPANAIKEMIENCLDAKSTSIQVIVKEGGLKLIQIQDNGTG 67
           +++L    V  +++ ++I    + +KE+IEN LDA +TS+ V ++  G   I+++DNG G
Sbjct: 1   MKQLPAATVRLLSSSQIITSVVSVVKELIENSLDAGATSVDVKLENYGFDKIEVRDNGEG 60

Query: 68  IRKEDLDIVCERFTTSKLQSFEDLASISTYGFRGEALASISHVAHVTITTKTADGKCAYR 127
           I+  D  ++  ++ TSK+ S EDL +++TYGFRGEAL SI  +A V ITT+TA    + +
Sbjct: 61  IKAVDAPVMAMKYYTSKINSHEDLENLTTYGFRGEALGSICCIAEVLITTRTAADNFSTQ 120

Query: 128 ASYSDGKLKAPPKPCAGNQGTQITVEDLFYNIATRRK---ALKNPSEEYGKILEVVGRYS 184
                       KP    QGT +T   LF N+  R++     K   +E  KI +++    
Sbjct: 121 YVLDGSGHILSQKPSHLGQGTTVTALRLFKNLPVRKQFYSTAKKCKDEIKKIQDLL---- 176

Query: 185 VHNAGISFSVKKQGETVADVRTLPNASTVDNIRSIFGNAVSRELIEIGCEDKTLAFKMNG 244
                +SF + K                  ++R +F   V  ++   G   K  A     
Sbjct: 177 -----MSFGILK-----------------PDLRIVF---VHNKIYLSGFLPKCDADHSFT 211

Query: 245 YISNANYSVKKCIFLLFINHRLVESTSLRKAIETVYAAYLPKNT---HPFLYLSLEISPQ 301
            +S    S       +FIN R V    + K I   Y     K +   +P  +L +++   
Sbjct: 212 SLSTPERS------FIFINSRPVHQKDILKLIRHHYNLKCLKESTRLYPVFFLKIDVPTA 265

Query: 302 NVDVNVHPTKHEVHFLHEESIL 323
           +VDVN+ P K +V   ++ES+L
Sbjct: 266 DVDVNLTPDKSQVLLQNKESVL 287


>gi|91992162 mutL homolog 3 isoform 1 [Homo sapiens]
          Length = 1453

 Score =  110 bits (276), Expect = 4e-24
 Identities = 105/351 (29%), Positives = 174/351 (49%), Gaps = 32/351 (9%)

Query: 7   VIRRLDETVVNRIAAGEVIQRPANAIKEMIENCLDAKSTSIQVIVKEGGLKLIQIQDNGT 66
           +I+ L   V  ++ +G  I      ++E+  N +DA++  + V V     + +Q+ DNG 
Sbjct: 1   MIKCLSVEVQAKLRSGLAISSLGQCVEELALNSIDAEAKCVAVRVNMETFQ-VQVIDNGF 59

Query: 67  GIRKEDLDIVCERFTTSKLQSFEDLASISTYGFRGEALASISHVAH-VTITTKTADGKCA 125
           G+  +D++ V  R+ TSK  S +DL +   YGFRGEALA+I+ +A  V I++K       
Sbjct: 60  GMGSDDVEKVGNRYFTSKCHSVQDLENPRFYGFRGEALANIADMASAVEISSKKNRTMKT 119

Query: 126 YRASYSDGK-LKA-PPKPCAGNQGTQITVEDLFYNIATRRKALKNPSEEYGKILEVVGRY 183
           +   +  GK LKA        + GT +TV +LFY +  RRK + +P  E+ K+ + +   
Sbjct: 120 FVKLFQSGKALKACEADVTRASAGTTVTVYNLFYQLPVRRKCM-DPRLEFEKVRQRIEAL 178

Query: 184 SVHNAGISFSVKKQGETVADVRTLPNASTV-DNIRSIFGNAVSRELIEIGCEDKTLAFKM 242
           S+ +  ISFS++    + + V  LP    V      I+G   S++L EI  + K   F++
Sbjct: 179 SLMHPSISFSLRND-VSGSMVLQLPKTKDVCSRFCQIYGLGKSQKLREISFKYK--EFEL 235

Query: 243 NGYISNANYSVKKCIFLLFINHRLVESTSLRKAIETVY----AAYLPKN----------- 287
           +GYIS+  +  K   F LF+N RLV  T L K I+ +         PKN           
Sbjct: 236 SGYISSEAHYNKNMQF-LFVNKRLVLRTKLHKLIDFLLRKESIICKPKNGPTSRQMNSSL 294

Query: 288 ---THPFLYLSLEISPQ----NVDVNVHPTKHEVHFLHEESILERVQQHIE 331
              + P LY    I+ Q      DV + P K  + F + +++L  +Q+ ++
Sbjct: 295 RHRSTPELYGIYVINVQCQFCEYDVCMEPAKTLIEFQNWDTLLFCIQEGVK 345


>gi|91992160 mutL homolog 3 isoform 2 [Homo sapiens]
          Length = 1429

 Score =  110 bits (276), Expect = 4e-24
 Identities = 105/351 (29%), Positives = 174/351 (49%), Gaps = 32/351 (9%)

Query: 7   VIRRLDETVVNRIAAGEVIQRPANAIKEMIENCLDAKSTSIQVIVKEGGLKLIQIQDNGT 66
           +I+ L   V  ++ +G  I      ++E+  N +DA++  + V V     + +Q+ DNG 
Sbjct: 1   MIKCLSVEVQAKLRSGLAISSLGQCVEELALNSIDAEAKCVAVRVNMETFQ-VQVIDNGF 59

Query: 67  GIRKEDLDIVCERFTTSKLQSFEDLASISTYGFRGEALASISHVAH-VTITTKTADGKCA 125
           G+  +D++ V  R+ TSK  S +DL +   YGFRGEALA+I+ +A  V I++K       
Sbjct: 60  GMGSDDVEKVGNRYFTSKCHSVQDLENPRFYGFRGEALANIADMASAVEISSKKNRTMKT 119

Query: 126 YRASYSDGK-LKA-PPKPCAGNQGTQITVEDLFYNIATRRKALKNPSEEYGKILEVVGRY 183
           +   +  GK LKA        + GT +TV +LFY +  RRK + +P  E+ K+ + +   
Sbjct: 120 FVKLFQSGKALKACEADVTRASAGTTVTVYNLFYQLPVRRKCM-DPRLEFEKVRQRIEAL 178

Query: 184 SVHNAGISFSVKKQGETVADVRTLPNASTV-DNIRSIFGNAVSRELIEIGCEDKTLAFKM 242
           S+ +  ISFS++    + + V  LP    V      I+G   S++L EI  + K   F++
Sbjct: 179 SLMHPSISFSLRND-VSGSMVLQLPKTKDVCSRFCQIYGLGKSQKLREISFKYK--EFEL 235

Query: 243 NGYISNANYSVKKCIFLLFINHRLVESTSLRKAIETVY----AAYLPKN----------- 287
           +GYIS+  +  K   F LF+N RLV  T L K I+ +         PKN           
Sbjct: 236 SGYISSEAHYNKNMQF-LFVNKRLVLRTKLHKLIDFLLRKESIICKPKNGPTSRQMNSSL 294

Query: 288 ---THPFLYLSLEISPQ----NVDVNVHPTKHEVHFLHEESILERVQQHIE 331
              + P LY    I+ Q      DV + P K  + F + +++L  +Q+ ++
Sbjct: 295 RHRSTPELYGIYVINVQCQFCEYDVCMEPAKTLIEFQNWDTLLFCIQEGVK 345


>gi|239743246 PREDICTED: hypothetical protein XP_002342778 [Homo
           sapiens]
          Length = 255

 Score = 97.8 bits (242), Expect = 3e-20
 Identities = 56/164 (34%), Positives = 99/164 (60%), Gaps = 8/164 (4%)

Query: 5   AGVIRRLDETVVNRIAAGEVIQRPANAIKEMIENCLDAKSTSIQVIVKEGGLKLIQIQDN 64
           A  I+ +D   V++I +G V+   + A+K+++ N LDA +T+I + +K+ G+ LI++  N
Sbjct: 27  AKAIKPIDRKSVHQICSGPVVLSLSTAVKKIVGNSLDAGATNIDLKLKDYGMDLIEVSGN 86

Query: 65  GTGIRKEDLDIVCERFTTSKLQSFEDLASISTYGFRGEALASISHVAHVTITTKTADGKC 124
           G G+ +E+ + +  +  TSK++ F DL  + T+GF+G+AL+S+  ++ VTI+T     K 
Sbjct: 87  GCGVEEENFEGLTLKHHTSKIREFADLTRVETFGFQGKALSSLCALSDVTISTCHVSAKV 146

Query: 125 AYRASYS-DGKL--KAP-PKPCAGNQGTQITVEDLFYNIATRRK 164
             R  +  DGK+  K P P P    +GT ++V+ LF  +  R K
Sbjct: 147 GTRLVFDHDGKIIQKTPYPHP----RGTTVSVKQLFSTLPVRHK 186


>gi|169170512 PREDICTED: similar to Postmeiotic segregation
           increased 4-like protein [Homo sapiens]
          Length = 255

 Score = 97.8 bits (242), Expect = 3e-20
 Identities = 56/164 (34%), Positives = 99/164 (60%), Gaps = 8/164 (4%)

Query: 5   AGVIRRLDETVVNRIAAGEVIQRPANAIKEMIENCLDAKSTSIQVIVKEGGLKLIQIQDN 64
           A  I+ +D   V++I +G V+   + A+K+++ N LDA +T+I + +K+ G+ LI++  N
Sbjct: 27  AKAIKPIDRKSVHQICSGPVVLSLSTAVKKIVGNSLDAGATNIDLKLKDYGMDLIEVSGN 86

Query: 65  GTGIRKEDLDIVCERFTTSKLQSFEDLASISTYGFRGEALASISHVAHVTITTKTADGKC 124
           G G+ +E+ + +  +  TSK++ F DL  + T+GF+G+AL+S+  ++ VTI+T     K 
Sbjct: 87  GCGVEEENFEGLTLKHHTSKIREFADLTRVETFGFQGKALSSLCALSDVTISTCHVSAKV 146

Query: 125 AYRASYS-DGKL--KAP-PKPCAGNQGTQITVEDLFYNIATRRK 164
             R  +  DGK+  K P P P    +GT ++V+ LF  +  R K
Sbjct: 147 GTRLVFDHDGKIIQKTPYPHP----RGTTVSVKQLFSTLPVRHK 186


>gi|19923559 EMSY protein [Homo sapiens]
          Length = 1322

 Score = 36.6 bits (83), Expect = 0.089
 Identities = 43/179 (24%), Positives = 74/179 (41%), Gaps = 40/179 (22%)

Query: 581 PLFDLAMLALDSPESGWTEEDGPKEGLAEYIVEFLKKKAEMLADYFSLEIDEEGNLIGLP 640
           P  DL+ +A+  P     E+    E  +  +VE     +E++A+Y + E  +EG  +  P
Sbjct: 798 PTIDLSQMAV--PIQMTQEKRHSPESPSIAVVE-----SELVAEYITTERTDEGTEVAFP 850

Query: 641 LLIDNYVPPLEGLPIFILRLATEVNWDEEKECFESLSKECAMFYSIRKQYISEESTLSGQ 700
           LL+ +   P +                       S  +   +      Q++++  T + Q
Sbjct: 851 LLVSHRSQPQQ----------------------PSQPQRTLL------QHVAQSQTAT-Q 881

Query: 701 QSEVPGSIPNSWKWTVEHIVYKALRSHILPPKHF----TEDGNILQLANLPDLYKVFER 755
            S V  SIP S    + HI+ +AL SH    KH     TE+G + ++  L     +F R
Sbjct: 882 TSVVVKSIPASSPGAITHIMQQALSSHTAFTKHSEELGTEEGEVEEMDTLDPQTGLFYR 940


>gi|50843827 activating molecule in beclin-1-regulated autophagy
           [Homo sapiens]
          Length = 1208

 Score = 35.8 bits (81), Expect = 0.15
 Identities = 44/177 (24%), Positives = 68/177 (38%), Gaps = 19/177 (10%)

Query: 348 LLPGLAGPSGEMVKSTTSLTSSSTSGSSDKVYAHQMVRTDSREQKLDAFLQPLSKPLSSQ 407
           LL  +  PS +       +    T  S    +  Q     S+  +    L      LSS+
Sbjct: 195 LLTAIVNPSNQQGDDEPEIPIDGTELS----HYRQRALLQSQPVRRTPLLHNFLHMLSSR 250

Query: 408 PQAIVTEDKTDISSGRARQQDEEMLELPAPAEVAAKNQSLEGDTTKGTSEMSEKR---GP 464
              I TE         + QQD+ +L    P+  +    S  G+T +  S    +R   GP
Sbjct: 251 SSGIQTEPFHPPEQASSTQQDQGLLN--RPSAFSTVQSSTAGNTLRNLSLGPTRRSLGGP 308

Query: 465 TSSNPRKRHRE--------DSDVEMVEDDSRKEMTAACTPRRRI--INLTSVLSLQE 511
            SS+P + HRE        +    ++  +SR E  +   PR     ++L SVL  QE
Sbjct: 309 LSSHPSRYHREIAPGLTGSEWTRTVLSLNSRSEAESMPPPRTSASSVSLLSVLRQQE 365


>gi|7019405 host cell factor C2 [Homo sapiens]
          Length = 792

 Score = 35.8 bits (81), Expect = 0.15
 Identities = 25/76 (32%), Positives = 35/76 (46%), Gaps = 2/76 (2%)

Query: 337 SNSSRMYFTQTLLPGLAGPSGEMVKSTTSLTSSSTSGSSDKVYAHQMVRTDSREQKLDAF 396
           S++  M   QT+    +  +G +VK  TSLT+ ST    D+ YA  +  T     +  A 
Sbjct: 518 SSTQTMVTQQTIKTESSSTNGAVVKDETSLTTFSTKSEVDETYA--LPATKISRVETHAT 575

Query: 397 LQPLSKPLSSQPQAIV 412
             P SK   S P A V
Sbjct: 576 ATPFSKETPSNPVATV 591


>gi|5454016 retinitis pigmentosa RP1 protein [Homo sapiens]
          Length = 2156

 Score = 34.7 bits (78), Expect = 0.34
 Identities = 54/239 (22%), Positives = 93/239 (38%), Gaps = 32/239 (13%)

Query: 336 GSNSSRMYFTQTLLPGLAG---PSGEMVKSTTSLTSSSTSGSSDKVYAHQMVRTDSREQK 392
           G+   + Y     LPG++    P G     +  +++  +S S  ++Y+    +T + +  
Sbjct: 230 GNYDIQKYLLPARLPGISQRVYPKGNAKSESRKISTHMSSSSRSQIYSVSSEKTHNNDCY 289

Query: 393 LDAFLQP---LSKPLSSQPQAIVTEDKTDISSGRARQQDEEMLELPAPAEVAAKNQSLEG 449
           LD    P   L+   +      +   + DI       QD  M       E+  + +  E 
Sbjct: 290 LDYSFVPEKYLALEKNDSQNLPIYPSEDDIEKSIIFNQDGTM-----TVEMKVRFRIKEE 344

Query: 450 DTTKGTSEMSEKRGPTSSNPRKRHREDSDVEMVEDDSRKEMTAAC------TPRRRIINL 503
           +T K T+ +S K GP++++ +    E S     E  S     AAC      +P  R  N 
Sbjct: 345 ETIKWTTTVS-KTGPSNNDEKS---EMSFPGRTESRSSGLKLAACSFSADVSPMERSSNQ 400

Query: 504 TSVLSLQEEINEQGHEVLREMLHNHSFVGCVNPQWALAQHQTKLYLLNTTKLSEELFYQ 562
               SL EEIN Q  + + E         C +  W  A   T + +  T   ++  FY+
Sbjct: 401 EG--SLAEEINIQMTDQVAET--------CSSASWENATVDTDI-IQGTQDQAKHRFYR 448


>gi|13376367 WD repeat domain 76 [Homo sapiens]
          Length = 626

 Score = 34.7 bits (78), Expect = 0.34
 Identities = 52/220 (23%), Positives = 89/220 (40%), Gaps = 22/220 (10%)

Query: 360 VKSTTSLTSSSTSGSSDKVYAHQMVRTDSREQKLDAFLQPLSKPLSSQPQAIVTEDKTDI 419
           +K+T+S   S+   SS  V+      ++  + K  A    LS  + S       ED T  
Sbjct: 98  MKNTSSKAESTLQNSSSAVHTE----SNKLQPKRTADAMNLSVDVESSQDGDSDEDTTPA 153

Query: 420 S--SGRARQQDEEMLELPAPAEVAAKNQSLEGDTTKGTSEMSEKRGPTSSNPRKRHREDS 477
              SG +  + + +  +   A+  A  Q  E  +     EM EKR P  S  +K  RE+ 
Sbjct: 154 LDFSGLSPYERKRLKNISENADFFASLQLSE--SAARLREMIEKRQPPKSKRKKPKRENG 211

Query: 478 -----DVEMVE-DDSRKEMTAACTPRRRIINLTSV-----LSLQEEINEQGHEVLREMLH 526
                 + +++ D S   + AA TP   + + T +     L +  E  E  +E  +  LH
Sbjct: 212 IGCRRSMRLLKVDPSGVSLPAAPTPPTLVADETPLLPPGPLEMTSENQEDNNERFKGFLH 271

Query: 527 ---NHSFVGCVNPQWALAQHQTKLYLLNTTKLSEELFYQI 563
                S     N +  L+  ++    LN   +SE+  Y++
Sbjct: 272 TWAGMSKPSSKNTEKGLSSIKSYKANLNGMVISEDTVYKV 311


>gi|22538422 activating transcription factor 2 [Homo sapiens]
          Length = 505

 Score = 33.9 bits (76), Expect = 0.57
 Identities = 24/92 (26%), Positives = 40/92 (43%), Gaps = 10/92 (10%)

Query: 349 LPGLAGPSGEM-------VKSTTSLTSSS---TSGSSDKVYAHQMVRTDSREQKLDAFLQ 398
           +PG+ GPS          ++   +LT      T+G + K +   +VRT S E +  +  Q
Sbjct: 258 VPGIPGPSSPQPVQSEAKMRLKAALTQQHPPVTNGDTVKGHGSGLVRTQSEESRPQSLQQ 317

Query: 399 PLSKPLSSQPQAIVTEDKTDISSGRARQQDEE 430
           P +    +      T  +T  +SGR R+   E
Sbjct: 318 PATSTTETPASPAHTTPQTQSTSGRRRRAANE 349


>gi|82830424 gon-4-like isoform a [Homo sapiens]
          Length = 2240

 Score = 33.5 bits (75), Expect = 0.75
 Identities = 36/151 (23%), Positives = 60/151 (39%), Gaps = 18/151 (11%)

Query: 371  TSGSSDKVYAHQMVRTDSREQKLDAFLQPLSKPLSSQPQAIVTEDKTDISSGRARQQDEE 430
            T   S+++ +   V   +  QK +   QP   P SSQ         TD++ G ++     
Sbjct: 1358 TGAPSEELSSAGEVTKQTVLQKEEERSQPTKTPSSSQEPPDEGTSGTDVNKGSSKNALSS 1417

Query: 431  M---LELPAPAEVAAKNQSLEGD---TTKGTSEMSEKRGPTSSNPRKRHREDSDVEMVED 484
            M   + L +P      + S++G    T  G     EK GP          E+ D + +  
Sbjct: 1418 MDPEVRLSSPPGKPEDSSSVDGQSVGTPVGPETGGEKNGP-------EEEEEEDFDDLTQ 1470

Query: 485  DSRKEMTAACTPRRRIINLTSVLSLQEEINE 515
            D   EM++A        ++ SV  LQE + +
Sbjct: 1471 DEEDEMSSASEE-----SVLSVPELQETMEK 1496


>gi|217035133 hypothetical protein LOC55765 isoform 2 [Homo sapiens]
          Length = 578

 Score = 33.5 bits (75), Expect = 0.75
 Identities = 31/132 (23%), Positives = 51/132 (38%), Gaps = 15/132 (11%)

Query: 381 HQMVRTDSREQKLDAFLQPLSKPLSSQPQAIV-------TEDKTDISSGRARQQDEEML- 432
           H M++ + + Q+L   L    +     P A +         D + +S G   +++E  + 
Sbjct: 138 HSMLQEEKKLQELQRCLVERRRNSEPPPAAALPLGRELSASDDSSLSDGLLLEEEESQVP 197

Query: 433 ----ELPAPAEVAAKNQSLEGDTTKGTSEMSEKRGPTSSNPRKRHREDSDVEMVEDDSR- 487
               E PAP       Q+LEG    G    S +R P  ++P K    D   E     S  
Sbjct: 198 KPPPESPAPPSRPLPPQTLEGLQPTGPEAGSPERAPVQNSPWKETSLDHPYEKPRKSSEP 257

Query: 488 --KEMTAACTPR 497
             +  + A TP+
Sbjct: 258 WSESSSPATTPQ 269


>gi|217035131 hypothetical protein LOC55765 isoform 1 [Homo sapiens]
          Length = 663

 Score = 33.5 bits (75), Expect = 0.75
 Identities = 31/132 (23%), Positives = 51/132 (38%), Gaps = 15/132 (11%)

Query: 381 HQMVRTDSREQKLDAFLQPLSKPLSSQPQAIV-------TEDKTDISSGRARQQDEEML- 432
           H M++ + + Q+L   L    +     P A +         D + +S G   +++E  + 
Sbjct: 223 HSMLQEEKKLQELQRCLVERRRNSEPPPAAALPLGRELSASDDSSLSDGLLLEEEESQVP 282

Query: 433 ----ELPAPAEVAAKNQSLEGDTTKGTSEMSEKRGPTSSNPRKRHREDSDVEMVEDDSR- 487
               E PAP       Q+LEG    G    S +R P  ++P K    D   E     S  
Sbjct: 283 KPPPESPAPPSRPLPPQTLEGLQPTGPEAGSPERAPVQNSPWKETSLDHPYEKPRKSSEP 342

Query: 488 --KEMTAACTPR 497
             +  + A TP+
Sbjct: 343 WSESSSPATTPQ 354


>gi|83415174 hypothetical protein LOC400818 [Homo sapiens]
          Length = 942

 Score = 33.5 bits (75), Expect = 0.75
 Identities = 29/118 (24%), Positives = 52/118 (44%), Gaps = 8/118 (6%)

Query: 384 VRTDSREQKLDAFLQPL------SKPLSSQPQAIVTEDKTDISSGRARQQDEEMLELPAP 437
           V   S+E++L    + L      S+ L+   QA++T D+ D S G+  Q  E++ E    
Sbjct: 97  VLVHSQERELTQLKEKLREGRDASRSLNEHLQALLTPDEPDKSQGQDLQ--EQLAEGCRL 154

Query: 438 AEVAAKNQSLEGDTTKGTSEMSEKRGPTSSNPRKRHREDSDVEMVEDDSRKEMTAACT 495
           A+   +  S E D  +      E+      +P  R  + ++   V +DS +E    C+
Sbjct: 155 AQHLVQKLSPENDEDEDEDVQVEEDEKVLESPAPREVQKAEESKVTEDSLEECAITCS 212


>gi|27262628 nuclear autoantigenic sperm protein isoform 2 [Homo
           sapiens]
          Length = 788

 Score = 33.1 bits (74), Expect = 0.98
 Identities = 49/239 (20%), Positives = 103/239 (43%), Gaps = 23/239 (9%)

Query: 417 TDISSGRARQQDEEMLELPAPAEVAAKNQSL-EGDTTKGTSEMSEKRGPTSSNPRKRHRE 475
           T ++ G   +  E+ +++ A  E   + + + EG+ T+G+ E  ++   T   P     E
Sbjct: 441 TKVAQGATEKSPEDKVQIAANEETQEREEQMKEGEETEGSEEDDKENDKTEEMPNDSVLE 500

Query: 476 DSDVEMVEDDSRKEMTAACTPRRRIINLTSVLSLQEEINE------QGHEVLREM-LHNH 528
           +  ++  E++    +  A      +++L  ++  ++E  E      Q H  L E+ + + 
Sbjct: 501 NKSLQENEEEEIGNLELAWD----MLDLAKIIFKRQETKEAQLYAAQAHLKLGEVSVESE 556

Query: 529 SFVGCVNPQWALAQHQTKLYLLNTTKLSEELFYQI-LIYDF---ANFGVLRLSEPAPLFD 584
           ++V  V  ++    +  + YL    +L  E  YQ+ L Y +    +  V + S+   + +
Sbjct: 557 NYVQAVE-EFQSCLNLQEQYLEAHDRLLAETHYQLGLAYGYNSQYDEAVAQFSKSIEVIE 615

Query: 585 LAMLALDS--PESGWTEEDGPKEGLAEYIVEFLKKKAEMLADYFSLEIDEEGNLIGLPL 641
             M  L+    E+  +  +  KE   E + E L +  E + D  + E    GN+  L L
Sbjct: 616 NRMAVLNEQVKEAEGSSAEYKKE--IEELKELLPEIREKIED--AKESQRSGNVAELAL 670


>gi|27262634 nuclear autoantigenic sperm protein isoform 1 [Homo
           sapiens]
          Length = 790

 Score = 33.1 bits (74), Expect = 0.98
 Identities = 49/239 (20%), Positives = 103/239 (43%), Gaps = 23/239 (9%)

Query: 417 TDISSGRARQQDEEMLELPAPAEVAAKNQSL-EGDTTKGTSEMSEKRGPTSSNPRKRHRE 475
           T ++ G   +  E+ +++ A  E   + + + EG+ T+G+ E  ++   T   P     E
Sbjct: 443 TKVAQGATEKSPEDKVQIAANEETQEREEQMKEGEETEGSEEDDKENDKTEEMPNDSVLE 502

Query: 476 DSDVEMVEDDSRKEMTAACTPRRRIINLTSVLSLQEEINE------QGHEVLREM-LHNH 528
           +  ++  E++    +  A      +++L  ++  ++E  E      Q H  L E+ + + 
Sbjct: 503 NKSLQENEEEEIGNLELAWD----MLDLAKIIFKRQETKEAQLYAAQAHLKLGEVSVESE 558

Query: 529 SFVGCVNPQWALAQHQTKLYLLNTTKLSEELFYQI-LIYDF---ANFGVLRLSEPAPLFD 584
           ++V  V  ++    +  + YL    +L  E  YQ+ L Y +    +  V + S+   + +
Sbjct: 559 NYVQAVE-EFQSCLNLQEQYLEAHDRLLAETHYQLGLAYGYNSQYDEAVAQFSKSIEVIE 617

Query: 585 LAMLALDS--PESGWTEEDGPKEGLAEYIVEFLKKKAEMLADYFSLEIDEEGNLIGLPL 641
             M  L+    E+  +  +  KE   E + E L +  E + D  + E    GN+  L L
Sbjct: 618 NRMAVLNEQVKEAEGSSAEYKKE--IEELKELLPEIREKIED--AKESQRSGNVAELAL 672


>gi|11067749 bromodomain containing protein 3 [Homo sapiens]
          Length = 726

 Score = 33.1 bits (74), Expect = 0.98
 Identities = 38/157 (24%), Positives = 66/157 (42%), Gaps = 18/157 (11%)

Query: 350 PGLAGPSGEMV-----KSTTSLTSSSTSGSSDKVYAHQMVRTDSREQ------KLDAFLQ 398
           P L  P+  MV      S +S  SSS SGSSD          + +EQ      +L A  Q
Sbjct: 423 PALPAPAAPMVSKGAESSRSSEESSSDSGSSDSEEERATRLAELQEQLKAVHEQLAALSQ 482

Query: 399 -PLSKPLSSQPQAIVTEDKTD----ISSGRARQQDEEMLELPAPAEVA--AKNQSLEGDT 451
            P++KP   + +    + K D        + + ++E+  ++  PA+ A   K  + + ++
Sbjct: 483 APVNKPKKKKEKKEKEKKKKDKEKEKEKHKVKAEEEKKAKVAPPAKQAQQKKAPAKKANS 542

Query: 452 TKGTSEMSEKRGPTSSNPRKRHREDSDVEMVEDDSRK 488
           T       +K G  +S       E+  + M  D+ R+
Sbjct: 543 TTTAGRQLKKGGKQASASYDSEEEEEGLPMSYDEKRQ 579


>gi|82830428 gon-4-like isoform b [Homo sapiens]
          Length = 1529

 Score = 32.7 bits (73), Expect = 1.3
 Identities = 31/129 (24%), Positives = 51/129 (39%), Gaps = 13/129 (10%)

Query: 371  TSGSSDKVYAHQMVRTDSREQKLDAFLQPLSKPLSSQPQAIVTEDKTDISSGRARQQDEE 430
            T   S+++ +   V   +  QK +   QP   P SSQ         TD++ G ++     
Sbjct: 1358 TGAPSEELSSAGEVTKQTVLQKEEERSQPTKTPSSSQEPPDEGTSGTDVNKGSSKNALSS 1417

Query: 431  M---LELPAPAEVAAKNQSLEGD---TTKGTSEMSEKRGPTSSNPRKRHREDSDVEMVED 484
            M   + L +P      + S++G    T  G     EK GP          E+ D + +  
Sbjct: 1418 MDPEVRLSSPPGKPEDSSSVDGQSVGTPVGPETGGEKNGP-------EEEEEEDFDDLTQ 1470

Query: 485  DSRKEMTAA 493
            D   EM++A
Sbjct: 1471 DEEDEMSSA 1479


>gi|41352705 kinesin family member 3C [Homo sapiens]
          Length = 793

 Score = 32.7 bits (73), Expect = 1.3
 Identities = 32/166 (19%), Positives = 69/166 (41%), Gaps = 25/166 (15%)

Query: 382 QMVRTDSREQKLDAFLQPLSKPLSSQPQAI------VTEDKTDISSGRARQQDEEMLELP 435
           Q +   + E+ ++ +LQ   + L  +  AI      V+E+K  +   + +  ++   E  
Sbjct: 446 QPILESALEKNMENYLQEQKERLEEEKAAIQDDRSLVSEEKQKLLEEKEKMLEDLRREQQ 505

Query: 436 APAEVAAKNQSLEG----------DTTKGTSEMSEKRGPTSSNPRKRHREDSDVEMVEDD 485
           A   +AAK +++E           D T    +M E +    +  ++R RE     M+ D+
Sbjct: 506 ATELLAAKYKAMESKLLIGGRNIMDHTNEQQKMLELKRQEIAEQKRREREMQQEMMLRDE 565

Query: 486 SRKEMTAACTPRRRIINL---------TSVLSLQEEINEQGHEVLR 522
              E+    T  ++ + +           + +++ EI +Q  E +R
Sbjct: 566 ETMELRGTYTSLQQEVEVKTKKLKKLYAKLQAVKAEIQDQHDEYIR 611


>gi|118572613 splicing coactivator subunit SRm300 [Homo sapiens]
          Length = 2752

 Score = 32.7 bits (73), Expect = 1.3
 Identities = 36/139 (25%), Positives = 54/139 (38%), Gaps = 17/139 (12%)

Query: 361  KSTTSLTSSSTSGSSDKVYAHQMVRTDSREQKLDAFLQPLSKPLSSQPQAIVTEDKTDIS 420
            K+ T L   S SGSS +V        DS+ +     L P      S P+    +DK   +
Sbjct: 1568 KTRTPLRQRSRSGSSPEV--------DSKSR-----LSPRRSRSGSSPEV---KDKPR-A 1610

Query: 421  SGRARQQDEEMLELPAPAEVAAKNQSLEGDTTKGTSEMSEKRGPTSSNPRKRHREDSDVE 480
            + RA+   +   E  APA  A   +S  G ++KG     E    T S+P    +  +   
Sbjct: 1611 APRAQSGSDSSPEPKAPAPRALPRRSRSGSSSKGRGPSPEGSSSTESSPEHPPKSRTARR 1670

Query: 481  MVEDDSRKEMTAACTPRRR 499
                    +  +   PRRR
Sbjct: 1671 GSRSSPEPKTKSRTPPRRR 1689


>gi|5174573 myeloid/lymphoid or mixed-lineage leukemia trithorax
           homolog 2 [Homo sapiens]
          Length = 1210

 Score = 32.3 bits (72), Expect = 1.7
 Identities = 25/85 (29%), Positives = 39/85 (45%), Gaps = 7/85 (8%)

Query: 398 QPLSKPLSSQPQAIVTEDKTDIS-----SGRARQQDEEMLELPAPA-EVAAKNQ-SLEGD 450
           +P++   SS  ++  T D    S     S  +  ++ E LE PAP  E    N+  L+  
Sbjct: 459 EPVASAHSSSAESESTSDSDSSSDSESESSSSDSEENEPLETPAPEPEPPTTNKWQLDNW 518

Query: 451 TTKGTSEMSEKRGPTSSNPRKRHRE 475
            TK +   +   GP S+ P +RH E
Sbjct: 519 LTKVSQPAAPPEGPRSTEPPRRHPE 543


>gi|114158664 hypothetical protein LOC343505 [Homo sapiens]
          Length = 421

 Score = 32.3 bits (72), Expect = 1.7
 Identities = 23/89 (25%), Positives = 43/89 (48%), Gaps = 2/89 (2%)

Query: 401 SKPLSSQPQAIVTEDKTDISSGRARQQDEEMLELPAPAEVAAKNQSLEGDTTKGTSEMSE 460
           S  L+   QA++T DK D S G+  +  E++ E    A       S E DT +  ++ ++
Sbjct: 140 SHSLNQHLQALLTPDKHDNSQGQDFR--EQLAEGCRLARHLVHKLSPENDTDEDENDKTK 197

Query: 461 KRGPTSSNPRKRHREDSDVEMVEDDSRKE 489
           +      +P  R  + ++ + V +DS +E
Sbjct: 198 ELDKVQESPAPREEQKAEEKEVPEDSLEE 226


>gi|190014588 PC4 and SFRS1 interacting protein 1 isoform 2 [Homo
           sapiens]
          Length = 530

 Score = 32.0 bits (71), Expect = 2.2
 Identities = 30/134 (22%), Positives = 51/134 (38%), Gaps = 15/134 (11%)

Query: 356 SGEMVKSTTSLTSSSTSGSSDKVYAHQMVRTDSREQKLDAFLQPLSKPLSSQPQAIVTED 415
           S E V     +T+   +    K  A + V T+       A      K    + +   TE 
Sbjct: 129 SNEDVTKAVDITTPKAARRGRKRKAEKQVETEEAGVVTTATASVNLKVSPKRGRPAATEV 188

Query: 416 KTDISSGRARQQDEEMLELPAPAEVAAKNQSLEGDTTKGTSEMSEKRGPTSSNPRKRHRE 475
           K     GR +     M++ P P+E     +           + S+K+G     P+K+ ++
Sbjct: 189 KIPKPRGRPK-----MVKQPCPSESDIITEE----------DKSKKKGQEEKQPKKQPKK 233

Query: 476 DSDVEMVEDDSRKE 489
           D + +  ED  RKE
Sbjct: 234 DEEGQKEEDKPRKE 247


>gi|190014586 PC4 and SFRS1 interacting protein 1 isoform 1 [Homo
           sapiens]
          Length = 333

 Score = 32.0 bits (71), Expect = 2.2
 Identities = 30/134 (22%), Positives = 51/134 (38%), Gaps = 15/134 (11%)

Query: 356 SGEMVKSTTSLTSSSTSGSSDKVYAHQMVRTDSREQKLDAFLQPLSKPLSSQPQAIVTED 415
           S E V     +T+   +    K  A + V T+       A      K    + +   TE 
Sbjct: 129 SNEDVTKAVDITTPKAARRGRKRKAEKQVETEEAGVVTTATASVNLKVSPKRGRPAATEV 188

Query: 416 KTDISSGRARQQDEEMLELPAPAEVAAKNQSLEGDTTKGTSEMSEKRGPTSSNPRKRHRE 475
           K     GR +     M++ P P+E     +           + S+K+G     P+K+ ++
Sbjct: 189 KIPKPRGRPK-----MVKQPCPSESDIITEE----------DKSKKKGQEEKQPKKQPKK 233

Query: 476 DSDVEMVEDDSRKE 489
           D + +  ED  RKE
Sbjct: 234 DEEGQKEEDKPRKE 247


>gi|19923653 PC4 and SFRS1 interacting protein 1 isoform 2 [Homo
           sapiens]
          Length = 530

 Score = 32.0 bits (71), Expect = 2.2
 Identities = 30/134 (22%), Positives = 51/134 (38%), Gaps = 15/134 (11%)

Query: 356 SGEMVKSTTSLTSSSTSGSSDKVYAHQMVRTDSREQKLDAFLQPLSKPLSSQPQAIVTED 415
           S E V     +T+   +    K  A + V T+       A      K    + +   TE 
Sbjct: 129 SNEDVTKAVDITTPKAARRGRKRKAEKQVETEEAGVVTTATASVNLKVSPKRGRPAATEV 188

Query: 416 KTDISSGRARQQDEEMLELPAPAEVAAKNQSLEGDTTKGTSEMSEKRGPTSSNPRKRHRE 475
           K     GR +     M++ P P+E     +           + S+K+G     P+K+ ++
Sbjct: 189 KIPKPRGRPK-----MVKQPCPSESDIITEE----------DKSKKKGQEEKQPKKQPKK 233

Query: 476 DSDVEMVEDDSRKE 489
           D + +  ED  RKE
Sbjct: 234 DEEGQKEEDKPRKE 247


  Database: hs.faa
    Posted date:  Aug 4, 2009  4:42 PM
  Number of letters in database: 18,247,518
  Number of sequences in database:  37,866
  
Lambda     K      H
   0.315    0.131    0.372 

Gapped
Lambda     K      H
   0.267   0.0410    0.140 


Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Hits to DB: 27,811,258
Number of Sequences: 37866
Number of extensions: 1223916
Number of successful extensions: 4177
Number of sequences better than 10.0: 30
Number of HSP's better than 10.0 without gapping: 14
Number of HSP's successfully gapped in prelim test: 57
Number of HSP's that attempted gapping in prelim test: 4115
Number of HSP's gapped (non-prelim): 110
length of query: 756
length of database: 18,247,518
effective HSP length: 110
effective length of query: 646
effective length of database: 14,082,258
effective search space: 9097138668
effective search space used: 9097138668
T: 11
A: 40
X1: 16 ( 7.3 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 41 (21.6 bits)
S2: 66 (30.0 bits)

Search results were obtained with NCBI BLAST and RefSeq entries.


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Guide to the Human Genome
Copyright © 2010 by Stewart Scherer. All rights reserved.

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