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Search of human proteins with 45267835
BLASTP 2.2.11 [Jun-05-2005]
Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer,
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997),
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs", Nucleic Acids Res. 25:3389-3402.
Query= gi|45267835 ubiquitin specific protease 50 [Homo sapiens]
(339 letters)
Database: hs.faa
37,866 sequences; 18,247,518 total letters
Searching..................................................done
Score E
Sequences producing significant alignments: (bits) Value
gi|45267835 ubiquitin specific protease 50 [Homo sapiens] 718 0.0
gi|190684694 ubiquitin specific peptidase 8 [Homo sapiens] 220 2e-57
gi|190684692 ubiquitin specific peptidase 8 [Homo sapiens] 220 2e-57
gi|190684690 ubiquitin specific peptidase 8 [Homo sapiens] 220 2e-57
gi|28565285 ubiquitin specific peptidase 2 isoform b [Homo sapiens] 158 8e-39
gi|188528692 ubiquitin specific peptidase 2 isoform a [Homo sapi... 158 8e-39
gi|62243586 ubiquitin-specific protease 21 [Homo sapiens] 140 2e-33
gi|74027267 ubiquitin-specific protease 21 [Homo sapiens] 140 2e-33
gi|55770886 ubiquitin thiolesterase 3 [Homo sapiens] 129 3e-30
gi|41152235 ubiquitin specific protease 51 [Homo sapiens] 125 7e-29
gi|150010639 ubiquitin thiolesterase 22 [Homo sapiens] 115 7e-26
gi|223005906 X-linked ubiquitin thioesterase 27 [Homo sapiens] 106 3e-23
gi|14149627 ubiquitin specific peptidase 15 [Homo sapiens] 101 8e-22
gi|40795665 ubiquitin specific protease 4 isoform a [Homo sapiens] 96 5e-20
gi|40795667 ubiquitin specific protease 4 isoform b [Homo sapiens] 96 5e-20
gi|109638751 ubiquitin specific protease 6 [Homo sapiens] 93 4e-19
gi|109134334 ubiquitin thiolesterase 44 [Homo sapiens] 92 5e-19
gi|109134332 ubiquitin thiolesterase 44 [Homo sapiens] 92 5e-19
gi|22550104 ubiquitin specific protease 32 [Homo sapiens] 91 1e-18
gi|21361749 ubiquitin thioesterase 49 [Homo sapiens] 89 6e-18
gi|197116355 ubiquitin specific peptidase 46 isoform 2 [Homo sap... 89 7e-18
gi|31377709 ubiquitin specific peptidase 46 isoform 1 [Homo sapi... 89 7e-18
gi|32698815 ubiquitin thiolesterase 12 [Homo sapiens] 88 1e-17
gi|120587027 ubiquitin specific peptidase 31 [Homo sapiens] 87 2e-17
gi|148612811 ubiquitin specific protease 43 [Homo sapiens] 86 4e-17
gi|42516561 ubiquitin specific protease 33 isoform 3 [Homo sapiens] 85 1e-16
gi|24234683 ubiquitin specific peptidase 11 [Homo sapiens] 84 2e-16
gi|79750944 ubiquitin specific peptidase 42 [Homo sapiens] 83 4e-16
gi|42516567 ubiquitin specific protease 33 isoform 1 [Homo sapiens] 82 9e-16
gi|42516565 ubiquitin specific protease 33 isoform 2 [Homo sapiens] 82 9e-16
>gi|45267835 ubiquitin specific protease 50 [Homo sapiens]
Length = 339
Score = 718 bits (1853), Expect = 0.0
Identities = 339/339 (100%), Positives = 339/339 (100%)
Query: 1 MTSQPSLPADDFDIYHVLAECTDYYDTLPVKEADGNQPHFQGVTGLWNLGNTCCVNAISQ 60
MTSQPSLPADDFDIYHVLAECTDYYDTLPVKEADGNQPHFQGVTGLWNLGNTCCVNAISQ
Sbjct: 1 MTSQPSLPADDFDIYHVLAECTDYYDTLPVKEADGNQPHFQGVTGLWNLGNTCCVNAISQ 60
Query: 61 CLCSILPLVEYFLTGKYITALQKFLLPSDCSEVATAFAYLMTDMWLGDSDCVSPEIFWSA 120
CLCSILPLVEYFLTGKYITALQKFLLPSDCSEVATAFAYLMTDMWLGDSDCVSPEIFWSA
Sbjct: 61 CLCSILPLVEYFLTGKYITALQKFLLPSDCSEVATAFAYLMTDMWLGDSDCVSPEIFWSA 120
Query: 121 LGNLYPAFTKKMQQDAQEFLICVLNELHEALKKYHYSRRRSYEKGSTQRCCRKWITTETS 180
LGNLYPAFTKKMQQDAQEFLICVLNELHEALKKYHYSRRRSYEKGSTQRCCRKWITTETS
Sbjct: 121 LGNLYPAFTKKMQQDAQEFLICVLNELHEALKKYHYSRRRSYEKGSTQRCCRKWITTETS 180
Query: 181 IITQLFEEQLNYSIVCLKCEKCTYKNEVFTVFSLPIPSKYECSLRDCLQCFFQQDALTWN 240
IITQLFEEQLNYSIVCLKCEKCTYKNEVFTVFSLPIPSKYECSLRDCLQCFFQQDALTWN
Sbjct: 181 IITQLFEEQLNYSIVCLKCEKCTYKNEVFTVFSLPIPSKYECSLRDCLQCFFQQDALTWN 240
Query: 241 NEIHCSFCETKQETAVRASISKAPKIIIFHLKRFDIQGTTKRKLRTDIHYPLTNLDLTPY 300
NEIHCSFCETKQETAVRASISKAPKIIIFHLKRFDIQGTTKRKLRTDIHYPLTNLDLTPY
Sbjct: 241 NEIHCSFCETKQETAVRASISKAPKIIIFHLKRFDIQGTTKRKLRTDIHYPLTNLDLTPY 300
Query: 301 ICSIFRKYPKYNLCAVVNHFGDLDGGHYTAFCKNSVTQA 339
ICSIFRKYPKYNLCAVVNHFGDLDGGHYTAFCKNSVTQA
Sbjct: 301 ICSIFRKYPKYNLCAVVNHFGDLDGGHYTAFCKNSVTQA 339
>gi|190684694 ubiquitin specific peptidase 8 [Homo sapiens]
Length = 1118
Score = 220 bits (560), Expect = 2e-57
Identities = 115/303 (37%), Positives = 168/303 (55%), Gaps = 7/303 (2%)
Query: 43 VTGLWNLGNTCCVNAISQCLCSILPLVEYFLTGKYITALQKFLLPSDCSEVATAFAYLMT 102
+TGL NLGNTC +N+I QCLC+ L +YF Y + + L EVA F +M
Sbjct: 776 LTGLRNLGNTCYMNSILQCLCNAPHLADYFNRNCYQDDINRSNLLGHKGEVAEEFGIIMK 835
Query: 103 DMWLGDSDCVSPEIFWSALGNLYPAFTKKMQQDAQEFLICVLNELHEALKKYHYSRRRSY 162
+W G +SP+ F +G + F QQD+QE L+ +++ LHE L K +R
Sbjct: 836 ALWTGQYRYISPKDFKITIGKINDQFAGYSQQDSQELLLFLMDGLHEDLNKADNRKRYKE 895
Query: 163 EKG-------STQRCCRKWITTETSIITQLFEEQLNYSIVCLKCEKCTYKNEVFTVFSLP 215
E + + +K SII LF+ Q ++ CL C K + E F SLP
Sbjct: 896 ENNDHLDDFKAAEHAWQKHKQLNESIIVALFQGQFKSTVQCLTCHKKSRTFEAFMYLSLP 955
Query: 216 IPSKYECSLRDCLQCFFQQDALTWNNEIHCSFCETKQETAVRASISKAPKIIIFHLKRFD 275
+ S +C+L+DCL+ F +++ LT NN +CS C ++++ + I K P +++ HLKRF
Sbjct: 956 LASTSKCTLQDCLRLFSKEEKLTDNNRFYCSHCRARRDSLKKIEIWKLPPVLLVHLKRFS 1015
Query: 276 IQGTTKRKLRTDIHYPLTNLDLTPYICSIFRKYPKYNLCAVVNHFGDLDGGHYTAFCKNS 335
G K+KL+T + +PL NLDL+ Y+ KYNL +V NH+G LDGGHYTA+CKN+
Sbjct: 1016 YDGRWKQKLQTSVDFPLENLDLSQYVIGPKNNLKKYNLFSVSNHYGGLDGGHYTAYCKNA 1075
Query: 336 VTQ 338
Q
Sbjct: 1076 ARQ 1078
>gi|190684692 ubiquitin specific peptidase 8 [Homo sapiens]
Length = 1118
Score = 220 bits (560), Expect = 2e-57
Identities = 115/303 (37%), Positives = 168/303 (55%), Gaps = 7/303 (2%)
Query: 43 VTGLWNLGNTCCVNAISQCLCSILPLVEYFLTGKYITALQKFLLPSDCSEVATAFAYLMT 102
+TGL NLGNTC +N+I QCLC+ L +YF Y + + L EVA F +M
Sbjct: 776 LTGLRNLGNTCYMNSILQCLCNAPHLADYFNRNCYQDDINRSNLLGHKGEVAEEFGIIMK 835
Query: 103 DMWLGDSDCVSPEIFWSALGNLYPAFTKKMQQDAQEFLICVLNELHEALKKYHYSRRRSY 162
+W G +SP+ F +G + F QQD+QE L+ +++ LHE L K +R
Sbjct: 836 ALWTGQYRYISPKDFKITIGKINDQFAGYSQQDSQELLLFLMDGLHEDLNKADNRKRYKE 895
Query: 163 EKG-------STQRCCRKWITTETSIITQLFEEQLNYSIVCLKCEKCTYKNEVFTVFSLP 215
E + + +K SII LF+ Q ++ CL C K + E F SLP
Sbjct: 896 ENNDHLDDFKAAEHAWQKHKQLNESIIVALFQGQFKSTVQCLTCHKKSRTFEAFMYLSLP 955
Query: 216 IPSKYECSLRDCLQCFFQQDALTWNNEIHCSFCETKQETAVRASISKAPKIIIFHLKRFD 275
+ S +C+L+DCL+ F +++ LT NN +CS C ++++ + I K P +++ HLKRF
Sbjct: 956 LASTSKCTLQDCLRLFSKEEKLTDNNRFYCSHCRARRDSLKKIEIWKLPPVLLVHLKRFS 1015
Query: 276 IQGTTKRKLRTDIHYPLTNLDLTPYICSIFRKYPKYNLCAVVNHFGDLDGGHYTAFCKNS 335
G K+KL+T + +PL NLDL+ Y+ KYNL +V NH+G LDGGHYTA+CKN+
Sbjct: 1016 YDGRWKQKLQTSVDFPLENLDLSQYVIGPKNNLKKYNLFSVSNHYGGLDGGHYTAYCKNA 1075
Query: 336 VTQ 338
Q
Sbjct: 1076 ARQ 1078
>gi|190684690 ubiquitin specific peptidase 8 [Homo sapiens]
Length = 1118
Score = 220 bits (560), Expect = 2e-57
Identities = 115/303 (37%), Positives = 168/303 (55%), Gaps = 7/303 (2%)
Query: 43 VTGLWNLGNTCCVNAISQCLCSILPLVEYFLTGKYITALQKFLLPSDCSEVATAFAYLMT 102
+TGL NLGNTC +N+I QCLC+ L +YF Y + + L EVA F +M
Sbjct: 776 LTGLRNLGNTCYMNSILQCLCNAPHLADYFNRNCYQDDINRSNLLGHKGEVAEEFGIIMK 835
Query: 103 DMWLGDSDCVSPEIFWSALGNLYPAFTKKMQQDAQEFLICVLNELHEALKKYHYSRRRSY 162
+W G +SP+ F +G + F QQD+QE L+ +++ LHE L K +R
Sbjct: 836 ALWTGQYRYISPKDFKITIGKINDQFAGYSQQDSQELLLFLMDGLHEDLNKADNRKRYKE 895
Query: 163 EKG-------STQRCCRKWITTETSIITQLFEEQLNYSIVCLKCEKCTYKNEVFTVFSLP 215
E + + +K SII LF+ Q ++ CL C K + E F SLP
Sbjct: 896 ENNDHLDDFKAAEHAWQKHKQLNESIIVALFQGQFKSTVQCLTCHKKSRTFEAFMYLSLP 955
Query: 216 IPSKYECSLRDCLQCFFQQDALTWNNEIHCSFCETKQETAVRASISKAPKIIIFHLKRFD 275
+ S +C+L+DCL+ F +++ LT NN +CS C ++++ + I K P +++ HLKRF
Sbjct: 956 LASTSKCTLQDCLRLFSKEEKLTDNNRFYCSHCRARRDSLKKIEIWKLPPVLLVHLKRFS 1015
Query: 276 IQGTTKRKLRTDIHYPLTNLDLTPYICSIFRKYPKYNLCAVVNHFGDLDGGHYTAFCKNS 335
G K+KL+T + +PL NLDL+ Y+ KYNL +V NH+G LDGGHYTA+CKN+
Sbjct: 1016 YDGRWKQKLQTSVDFPLENLDLSQYVIGPKNNLKKYNLFSVSNHYGGLDGGHYTAYCKNA 1075
Query: 336 VTQ 338
Q
Sbjct: 1076 ARQ 1078
>gi|28565285 ubiquitin specific peptidase 2 isoform b [Homo sapiens]
Length = 396
Score = 158 bits (399), Expect = 8e-39
Identities = 106/312 (33%), Positives = 156/312 (50%), Gaps = 13/312 (4%)
Query: 36 NQPHFQGVTGLWNLGNTCCVNAISQCLCSILPLVEYFLTGKYITALQKFLLPSDCSEVAT 95
N QG+ GL NLGNTC +N+I QCL + L +Y L Y+ L + + +
Sbjct: 50 NSKSAQGLAGLRNLGNTCFMNSILQCLSNTRELRDYCLQRLYMRDLHHG--SNAHTALVE 107
Query: 96 AFAYLMTDMWLGD-SDCVSPEIFWSALGNLYPAFTKKMQQDAQEFLICVLNELHEALKKY 154
FA L+ +W +D VSP F + + P F QQDAQEFL +L+ LH + +
Sbjct: 108 EFAKLIQTIWTSSPNDVVSPSEFKTQIQRYAPRFVGYNQQDAQEFLRFLLDGLHNEVNRV 167
Query: 155 HYSRRRSYEK-------GSTQRCCRKWITTETSIITQLFEEQLNYSIVCLKCEKCTYKNE 207
+ + E ++ RK++ E S I LF QL S+ C C C+ +
Sbjct: 168 TLRPKSNPENLDHLPDDEKGRQMWRKYLEREDSRIGDLFVGQLKSSLTCTDCGYCSTVFD 227
Query: 208 VFTVFSLPIPSKY--ECSLRDCLQCFFQQDALTWNNEIHCSFCETKQETAVRASISKAPK 265
F SLPI + E +L DC++ F ++D L + + C C ++ + SI + PK
Sbjct: 228 PFWDLSLPIAKRGYPEVTLMDCMRLFTKEDVLDGDEKPTCCRCRGRKRCIKKFSIQRFPK 287
Query: 266 IIIFHLKRFDIQGTTKRKLRTDIHYPLTNLDLTPYICSIFRKYPKYNLCAVVNHFGDLDG 325
I++ HLKRF KL T +++PL +LDL + S + YNL AV NH G G
Sbjct: 288 ILVLHLKRFSESRIRTSKLTTFVNFPLRDLDLREF-ASENTNHAVYNLYAVSNHSGTTMG 346
Query: 326 GHYTAFCKNSVT 337
GHYTA+C++ T
Sbjct: 347 GHYTAYCRSPGT 358
>gi|188528692 ubiquitin specific peptidase 2 isoform a [Homo
sapiens]
Length = 605
Score = 158 bits (399), Expect = 8e-39
Identities = 106/312 (33%), Positives = 156/312 (50%), Gaps = 13/312 (4%)
Query: 36 NQPHFQGVTGLWNLGNTCCVNAISQCLCSILPLVEYFLTGKYITALQKFLLPSDCSEVAT 95
N QG+ GL NLGNTC +N+I QCL + L +Y L Y+ L + + +
Sbjct: 259 NSKSAQGLAGLRNLGNTCFMNSILQCLSNTRELRDYCLQRLYMRDLHHG--SNAHTALVE 316
Query: 96 AFAYLMTDMWLGD-SDCVSPEIFWSALGNLYPAFTKKMQQDAQEFLICVLNELHEALKKY 154
FA L+ +W +D VSP F + + P F QQDAQEFL +L+ LH + +
Sbjct: 317 EFAKLIQTIWTSSPNDVVSPSEFKTQIQRYAPRFVGYNQQDAQEFLRFLLDGLHNEVNRV 376
Query: 155 HYSRRRSYEK-------GSTQRCCRKWITTETSIITQLFEEQLNYSIVCLKCEKCTYKNE 207
+ + E ++ RK++ E S I LF QL S+ C C C+ +
Sbjct: 377 TLRPKSNPENLDHLPDDEKGRQMWRKYLEREDSRIGDLFVGQLKSSLTCTDCGYCSTVFD 436
Query: 208 VFTVFSLPIPSKY--ECSLRDCLQCFFQQDALTWNNEIHCSFCETKQETAVRASISKAPK 265
F SLPI + E +L DC++ F ++D L + + C C ++ + SI + PK
Sbjct: 437 PFWDLSLPIAKRGYPEVTLMDCMRLFTKEDVLDGDEKPTCCRCRGRKRCIKKFSIQRFPK 496
Query: 266 IIIFHLKRFDIQGTTKRKLRTDIHYPLTNLDLTPYICSIFRKYPKYNLCAVVNHFGDLDG 325
I++ HLKRF KL T +++PL +LDL + S + YNL AV NH G G
Sbjct: 497 ILVLHLKRFSESRIRTSKLTTFVNFPLRDLDLREF-ASENTNHAVYNLYAVSNHSGTTMG 555
Query: 326 GHYTAFCKNSVT 337
GHYTA+C++ T
Sbjct: 556 GHYTAYCRSPGT 567
>gi|62243586 ubiquitin-specific protease 21 [Homo sapiens]
Length = 565
Score = 140 bits (352), Expect = 2e-33
Identities = 104/324 (32%), Positives = 147/324 (45%), Gaps = 41/324 (12%)
Query: 42 GVTGLWNLGNTCCVNAISQCLCSILPLVEYFLTGKYITALQKFLLPSDCSEVATAFAYLM 101
G GL NLGNTC +NA+ QCL S PL ++ L + Q+ E+ AFA ++
Sbjct: 210 GHVGLRNLGNTCFLNAVLQCLSSTRPLRDFCLRRDF---RQEVPGGGRAQELTEAFADVI 266
Query: 102 TDMWLGDS-DCVSPEIFWSALGNLYPAFTKKMQQDAQEFLICVLNELHEALKKYHYSRR- 159
+W DS + V+P F + P+F+ QQDAQEFL ++ LH + + RR
Sbjct: 267 GALWHPDSCEAVNPTRFRAVFQKYVPSFSGYSQQDAQEFLKLLMERLHLEINRR--GRRA 324
Query: 160 --------------------RSYEKGSTQRCCRKW---ITTETSIITQLFEEQLNYSIVC 196
E R W + E S I LF QL C
Sbjct: 325 PPILANGPVPSPPRRGGALLEEPELSDDDRANLMWKRYLEREDSKIVDLFVGQLKS---C 381
Query: 197 LKCEKCTYKNEVFTVF---SLPIPSKY----ECSLRDCLQCFFQQDALTWNNEIHCSFCE 249
LKC+ C Y++ F VF SLPIP K + SLRDC F +++ L N C C
Sbjct: 382 LKCQACGYRSTTFEVFCDLSLPIPKKGFAGGKVSLRDCFNLFTKEEELESENAPVCDRCR 441
Query: 250 TKQETAVRASISKAPKIIIFHLKRFDIQGTTKRKLRTDIHYPLTNLDLTPYICSIFRKYP 309
K + + ++ + P+I++ HL RF + +K + +PL L L + S P
Sbjct: 442 QKTRSTKKLTVQRFPRILVLHLNRFSASRGSIKKSSVGVDFPLQRLSLGDF-ASDKAGSP 500
Query: 310 KYNLCAVVNHFGDLDGGHYTAFCK 333
Y L A+ NH G + GHYTA C+
Sbjct: 501 VYQLYALCNHSGSVHYGHYTALCR 524
>gi|74027267 ubiquitin-specific protease 21 [Homo sapiens]
Length = 565
Score = 140 bits (352), Expect = 2e-33
Identities = 104/324 (32%), Positives = 147/324 (45%), Gaps = 41/324 (12%)
Query: 42 GVTGLWNLGNTCCVNAISQCLCSILPLVEYFLTGKYITALQKFLLPSDCSEVATAFAYLM 101
G GL NLGNTC +NA+ QCL S PL ++ L + Q+ E+ AFA ++
Sbjct: 210 GHVGLRNLGNTCFLNAVLQCLSSTRPLRDFCLRRDF---RQEVPGGGRAQELTEAFADVI 266
Query: 102 TDMWLGDS-DCVSPEIFWSALGNLYPAFTKKMQQDAQEFLICVLNELHEALKKYHYSRR- 159
+W DS + V+P F + P+F+ QQDAQEFL ++ LH + + RR
Sbjct: 267 GALWHPDSCEAVNPTRFRAVFQKYVPSFSGYSQQDAQEFLKLLMERLHLEINRR--GRRA 324
Query: 160 --------------------RSYEKGSTQRCCRKW---ITTETSIITQLFEEQLNYSIVC 196
E R W + E S I LF QL C
Sbjct: 325 PPILANGPVPSPPRRGGALLEEPELSDDDRANLMWKRYLEREDSKIVDLFVGQLKS---C 381
Query: 197 LKCEKCTYKNEVFTVF---SLPIPSKY----ECSLRDCLQCFFQQDALTWNNEIHCSFCE 249
LKC+ C Y++ F VF SLPIP K + SLRDC F +++ L N C C
Sbjct: 382 LKCQACGYRSTTFEVFCDLSLPIPKKGFAGGKVSLRDCFNLFTKEEELESENAPVCDRCR 441
Query: 250 TKQETAVRASISKAPKIIIFHLKRFDIQGTTKRKLRTDIHYPLTNLDLTPYICSIFRKYP 309
K + + ++ + P+I++ HL RF + +K + +PL L L + S P
Sbjct: 442 QKTRSTKKLTVQRFPRILVLHLNRFSASRGSIKKSSVGVDFPLQRLSLGDF-ASDKAGSP 500
Query: 310 KYNLCAVVNHFGDLDGGHYTAFCK 333
Y L A+ NH G + GHYTA C+
Sbjct: 501 VYQLYALCNHSGSVHYGHYTALCR 524
>gi|55770886 ubiquitin thiolesterase 3 [Homo sapiens]
Length = 520
Score = 129 bits (325), Expect = 3e-30
Identities = 102/321 (31%), Positives = 146/321 (45%), Gaps = 37/321 (11%)
Query: 44 TGLWNLGNTCCVNAISQCLCSI---------LPLVEYFLTGKYITALQKFLLPSDCSEVA 94
TGL NLGNTC +NAI Q L +I LP VE GK + V+
Sbjct: 159 TGLRNLGNTCFMNAILQSLSNIEQFCCYFKELPAVE-LRNGKTAGRRTYHTRSQGDNNVS 217
Query: 95 TA--FAYLMTDMWLGDSDCVSPEIFWSALGNLYPAFTKKMQQDAQEFLICVLNELHEALK 152
F + +W G SPE + + + P F QQDA EF+ +L+ LH L+
Sbjct: 218 LVEEFRKTLCALWQGSQTAFSPESLFYVVWKIMPNFRGYQQQDAHEFMRYLLDHLHLELQ 277
Query: 153 KYH--YSRRRSYEKGST----QRCCRKWITTETSIITQLFEEQLNYSIVCLKCEKCTYKN 206
SR ++ ST +CC I ++++T +F L + CL C + K
Sbjct: 278 GGFNGVSRSAILQENSTLSASNKCC---INGASTVVTAIFGGILQNEVNCLICGTESRKF 334
Query: 207 EVFTVFSLPIPSKYE------------CSLRDCLQCFFQQDALTWNNEIHCSFCETKQET 254
+ F SL IPS++ CSLRDCL+ F + L C C+ KQ++
Sbjct: 335 DPFLDLSLDIPSQFRSKRSKNQENGPVCSLRDCLRSFTDLEELDETELYMCHKCKKKQKS 394
Query: 255 AVRASISKAPKIIIFHLKRFDIQGTTKRKLRTDIHYPLTNLDLTPYICSIFRKYPK---Y 311
+ I K PK++ HLKRF + K+ T + +PL LD+ Y+ P+ Y
Sbjct: 395 TKKFWIQKLPKVLCLHLKRFHWTAYLRNKVDTYVEFPLRGLDMKCYLLEPENSGPESCLY 454
Query: 312 NLCAVVNHFGD-LDGGHYTAF 331
+L AVV H G + GHYTA+
Sbjct: 455 DLAAVVVHHGSGVGSGHYTAY 475
>gi|41152235 ubiquitin specific protease 51 [Homo sapiens]
Length = 711
Score = 125 bits (313), Expect = 7e-29
Identities = 100/350 (28%), Positives = 151/350 (43%), Gaps = 61/350 (17%)
Query: 29 PVKEADGNQPHFQGVTGLWNLGNTCCVNAISQCLCSILPLVEYFLTGKYITALQKFLLPS 88
P K+ + G+ GL NLGNTC +N I Q L I L ++FL+ K+ K ++ S
Sbjct: 348 PKKKRRKKSVYTVGLRGLINLGNTCFMNCIVQALTHIPLLKDFFLSDKH-----KCIMTS 402
Query: 89 DCSEVATAFAYLMTDMWLGDSDCVSPEIFWSALGNLY---PAFTKKMQQDAQEFLICVLN 145
+ + L M+ G +P I + L ++ QQDA EFLI +L+
Sbjct: 403 PSLCLVCEMSSLFHAMYSGSR---TPHIPYKLLHLIWIHAEHLAGYRQQDAHEFLIAILD 459
Query: 146 ELHEALKKYHYSRRRSYEKGSTQRCCRKWITTETSIITQLFEEQLNYSIVCLKCEKCTYK 205
LH H ++ + CC II Q+F L + C C +
Sbjct: 460 VLHR-----HSKDDSGGQEANNPNCCN-------CIIDQIFTGGLQSDVTCQACHSVSTT 507
Query: 206 NEVFTVFSLPIPSKYEC-----------------------SLRDCLQCFFQQDALTWNNE 242
+ SL +P SL DCLQ F + + L + +
Sbjct: 508 IDPCWDISLDLPGSCATFDSQNPERADSTVSRDDHIPGIPSLTDCLQWFTRPEHLGSSAK 567
Query: 243 IHCSFCETKQETAVRASISKAPKIIIFHLKRFDIQGTTKRKLRTDIHYPLTNLDLTPYIC 302
I C+ C++ QE+ + ++ K P + FHLKRF+ G +RK+ T I +PL LD+TP++
Sbjct: 568 IKCNSCQSYQESTKQLTMKKLPIVACFHLKRFEHVGKQRRKINTFISFPL-ELDMTPFLA 626
Query: 303 S--------------IFRKYPKYNLCAVVNHFGDLDGGHYTAFCKNSVTQ 338
S KY+L AV+NH G L+ GHYT+F + Q
Sbjct: 627 STKESRMKEGQPPTDCVPNENKYSLFAVINHHGTLESGHYTSFIRQQKDQ 676
>gi|150010639 ubiquitin thiolesterase 22 [Homo sapiens]
Length = 525
Score = 115 bits (287), Expect = 7e-26
Identities = 97/338 (28%), Positives = 145/338 (42%), Gaps = 62/338 (18%)
Query: 42 GVTGLWNLGNTCCVNAISQCLCSILPLVEYFLTGKYITALQKFLLPSDCSEVATAFAYLM 101
G+ GL NLGNTC +N I Q L L ++FL+ ++ +Q PS C + + L
Sbjct: 174 GLRGLINLGNTCFMNCIVQALTHTPLLRDFFLSDRHRCEMQS---PSSC--LVCEMSSLF 228
Query: 102 TDMWLGDSDCVSPEIFWSALGNLYPA---FTKKMQQDAQEFLICVLNELHEALKKYHYSR 158
+ + G SP I + L ++ QQDA EFLI L+ LH H
Sbjct: 229 QEFYSGHR---SPHIPYKLLHLVWTHARHLAGYEQQDAHEFLIAALDVLHR-----HCKG 280
Query: 159 RRSYEKGSTQRCCRKWITTETSIITQLFEEQLNYSIVCLKCEKCTYKNEVFTVFSLPIPS 218
+ +K + C II Q+F L + C C + + F SL +P
Sbjct: 281 DDNGKKANNPNHCN-------CIIDQIFTGGLQSDVTCQVCHGVSTTIDPFWDISLDLPG 333
Query: 219 KYE-----------------------CSLRDCLQCFFQQDALTWNNEIHCSFCETKQETA 255
+L DCL+ F + + L + +I CS C + QE+
Sbjct: 334 SSTPFWPLSPGSEGNVVNGESHVSGTTTLTDCLRRFTRPEHLGSSAKIKCSGCHSYQEST 393
Query: 256 VRASISKAPKIIIFHLKRFDIQGTTKRKLRTDIHYPLTNLDLTPYICS------------ 303
+ ++ K P + FHLKRF+ +RK+ T + +PL LD+TP++ S
Sbjct: 394 KQLTMKKLPIVACFHLKRFEHSAKLRRKITTYVSFPL-ELDMTPFMASSKESRMNGQYQQ 452
Query: 304 ---IFRKYPKYNLCAVVNHFGDLDGGHYTAFCKNSVTQ 338
KY+L AVVNH G L+ GHYT+F + Q
Sbjct: 453 PTDSLNNDNKYSLFAVVNHQGTLESGHYTSFIRQHKDQ 490
>gi|223005906 X-linked ubiquitin thioesterase 27 [Homo sapiens]
Length = 438
Score = 106 bits (264), Expect = 3e-23
Identities = 91/337 (27%), Positives = 145/337 (43%), Gaps = 61/337 (18%)
Query: 42 GVTGLWNLGNTCCVNAISQCLCSILPLVEYFLTGKYITALQKFLLPSDCSEVATAFAYLM 101
G+ GL NLGNTC +N I Q L L ++FL+ ++ + +PS + + L
Sbjct: 76 GLRGLINLGNTCFMNCIVQALTHTPILRDFFLSDRH-----RCEMPSPELCLVCEMSSLF 130
Query: 102 TDMWLGDSDCVSPEIFWSALGNLY---PAFTKKMQQDAQEFLICVLNELHEALKKYHYSR 158
+++ G+ SP + + L ++ QQDA EFLI L+ LH K +
Sbjct: 131 RELYSGNP---SPHVPYKLLHLVWIHARHLAGYRQQDAHEFLIAALDVLHRHCKGDDVGK 187
Query: 159 RRSYEKGSTQRCCRKWITTETSIITQLFEEQLNYSIVCLKCEKCTYKNEVFTVFSLPIPS 218
+ + C II Q+F L + C C + + SL +P
Sbjct: 188 AAN----NPNHC--------NCIIDQIFTGGLQSDVTCQACHGVSTTIDPCWDISLDLPG 235
Query: 219 KYEC----------------------SLRDCLQCFFQQDALTWNNEIHCSFCETKQETAV 256
+L DCL+ F + + L + +I C C++ QE+
Sbjct: 236 SCTSFWPMSPGRESSVNGESHIPGITTLTDCLRRFTRPEHLGSSAKIKCGSCQSYQESTK 295
Query: 257 RASISKAPKIIIFHLKRFDIQGTTKRKLRTDIHYPLTNLDLTPYICS------------- 303
+ +++K P + FH KRF+ +RK+ T I +PL LD+TP++ S
Sbjct: 296 QLTMNKLPVVACFHFKRFEHSAKQRRKITTYISFPL-ELDMTPFMASSKESRMNGQLQLP 354
Query: 304 --IFRKYPKYNLCAVVNHFGDLDGGHYTAFCKNSVTQ 338
KY+L AVVNH G L+ GHYT+F ++ Q
Sbjct: 355 TNSGNNENKYSLFAVVNHQGTLESGHYTSFIRHHKDQ 391
>gi|14149627 ubiquitin specific peptidase 15 [Homo sapiens]
Length = 952
Score = 101 bits (252), Expect = 8e-22
Identities = 64/193 (33%), Positives = 93/193 (48%), Gaps = 13/193 (6%)
Query: 42 GVTGLWNLGNTCCVNAISQCLCSILPLVEYFLTGKYITALQKFLLPSDCSEVATAFAYLM 101
G+ GL NLGNTC +N+ QCL + PL EYFL KY L E+A ++A L+
Sbjct: 258 GLCGLSNLGNTCFMNSAIQCLSNTPPLTEYFLNDKYQEELNFDNPLGMRGEIAKSYAELI 317
Query: 102 TDMWLGDSDCVSPEIFWSALGNLYPAFTKKMQQDAQEFLICVLNELHEALKKYHYSRRRS 161
MW G V+P F + +G P F+ QQD QE L +L+ LHE L + R++
Sbjct: 318 KQMWSGKFSYVTPRAFKTQVGRFAPQFSGYQQQDCQELLAFLLDGLHEDLNRI---RKKP 374
Query: 162 Y----------EKGSTQRCCRKWITTETSIITQLFEEQLNYSIVCLKCEKCTYKNEVFTV 211
Y +K + + SII +F ++VC +C K + + F
Sbjct: 375 YIQLKDADGRPDKVVAEEAWENHLKRNDSIIVDIFHGLFKSTLVCPECAKISVTFDPFCY 434
Query: 212 FSLPIPSKYECSL 224
+LP+P K E +L
Sbjct: 435 LTLPLPMKKERTL 447
Score = 85.1 bits (209), Expect = 8e-17
Identities = 39/118 (33%), Positives = 66/118 (55%)
Query: 217 PSKYECSLRDCLQCFFQQDALTWNNEIHCSFCETKQETAVRASISKAPKIIIFHLKRFDI 276
P K L+DC++ F ++ L + +C C+ Q+ + + P +++ HLKRF
Sbjct: 752 PKKPFVKLKDCIELFTTKEKLGAEDPWYCPNCKEHQQATKKLDLWSLPPVLVVHLKRFSY 811
Query: 277 QGTTKRKLRTDIHYPLTNLDLTPYICSIFRKYPKYNLCAVVNHFGDLDGGHYTAFCKN 334
+ KL T + +P+ +LD++ ++ + +YNL AV NH+G + GGHYTAF KN
Sbjct: 812 SRYMRDKLDTLVDFPINDLDMSEFLINPNAGPCRYNLIAVSNHYGGMGGGHYTAFAKN 869
>gi|40795665 ubiquitin specific protease 4 isoform a [Homo sapiens]
Length = 963
Score = 95.9 bits (237), Expect = 5e-20
Identities = 61/189 (32%), Positives = 92/189 (48%), Gaps = 8/189 (4%)
Query: 39 HFQ-GVTGLWNLGNTCCVNAISQCLCSILPLVEYFLTGKYITALQKFLLPSDCSEVATAF 97
H Q G+ GL NLGNTC +N+ QCL + PL +YFL +Y + + E+A A+
Sbjct: 296 HIQPGLCGLGNLGNTCFMNSALQCLSNTAPLTDYFLKDEYEAEINRDNPLGMKGEIAEAY 355
Query: 98 AYLMTDMWLGDSDCVSPEIFWSALGNLYPAFTKKMQQDAQEFLICVLNELHEAL----KK 153
A L+ MW G V+P +F + +G P F+ QQD+QE L +L+ LHE L KK
Sbjct: 356 AELIKQMWSGRDAHVAPRMFKTQVGRFAPQFSGYQQQDSQELLAFLLDGLHEDLNRVKKK 415
Query: 154 YHYSRRRSYEKGSTQRCCRKWIT---TETSIITQLFEEQLNYSIVCLKCEKCTYKNEVFT 210
+ + + + W S+I F ++VC +C K + + F
Sbjct: 416 PYLELKDANGRPDAVVAKEAWENHRLRNDSVIVDTFHGLFKSTLVCPECAKVSVTFDPFC 475
Query: 211 VFSLPIPSK 219
+LP+P K
Sbjct: 476 YLTLPLPLK 484
Score = 85.5 bits (210), Expect = 6e-17
Identities = 38/118 (32%), Positives = 68/118 (57%)
Query: 219 KYECSLRDCLQCFFQQDALTWNNEIHCSFCETKQETAVRASISKAPKIIIFHLKRFDIQG 278
K +LRDC++ F + L ++ +C C+ Q+ + + PKI++ HLKRF
Sbjct: 773 KTTVALRDCIELFTTMETLGEHDPWYCPNCKKHQQATKKFDLWSLPKILVVHLKRFSYNR 832
Query: 279 TTKRKLRTDIHYPLTNLDLTPYICSIFRKYPKYNLCAVVNHFGDLDGGHYTAFCKNSV 336
+ KL T + +P+ L+++ ++C++ + Y+L AV NH+G + GHYTA+ KN +
Sbjct: 833 YWRDKLDTVVEFPIRGLNMSEFVCNLSARPYVYDLIAVSNHYGAMGVGHYTAYAKNKL 890
>gi|40795667 ubiquitin specific protease 4 isoform b [Homo sapiens]
Length = 916
Score = 95.9 bits (237), Expect = 5e-20
Identities = 61/189 (32%), Positives = 92/189 (48%), Gaps = 8/189 (4%)
Query: 39 HFQ-GVTGLWNLGNTCCVNAISQCLCSILPLVEYFLTGKYITALQKFLLPSDCSEVATAF 97
H Q G+ GL NLGNTC +N+ QCL + PL +YFL +Y + + E+A A+
Sbjct: 249 HIQPGLCGLGNLGNTCFMNSALQCLSNTAPLTDYFLKDEYEAEINRDNPLGMKGEIAEAY 308
Query: 98 AYLMTDMWLGDSDCVSPEIFWSALGNLYPAFTKKMQQDAQEFLICVLNELHEAL----KK 153
A L+ MW G V+P +F + +G P F+ QQD+QE L +L+ LHE L KK
Sbjct: 309 AELIKQMWSGRDAHVAPRMFKTQVGRFAPQFSGYQQQDSQELLAFLLDGLHEDLNRVKKK 368
Query: 154 YHYSRRRSYEKGSTQRCCRKWIT---TETSIITQLFEEQLNYSIVCLKCEKCTYKNEVFT 210
+ + + + W S+I F ++VC +C K + + F
Sbjct: 369 PYLELKDANGRPDAVVAKEAWENHRLRNDSVIVDTFHGLFKSTLVCPECAKVSVTFDPFC 428
Query: 211 VFSLPIPSK 219
+LP+P K
Sbjct: 429 YLTLPLPLK 437
Score = 85.5 bits (210), Expect = 6e-17
Identities = 38/118 (32%), Positives = 68/118 (57%)
Query: 219 KYECSLRDCLQCFFQQDALTWNNEIHCSFCETKQETAVRASISKAPKIIIFHLKRFDIQG 278
K +LRDC++ F + L ++ +C C+ Q+ + + PKI++ HLKRF
Sbjct: 726 KTTVALRDCIELFTTMETLGEHDPWYCPNCKKHQQATKKFDLWSLPKILVVHLKRFSYNR 785
Query: 279 TTKRKLRTDIHYPLTNLDLTPYICSIFRKYPKYNLCAVVNHFGDLDGGHYTAFCKNSV 336
+ KL T + +P+ L+++ ++C++ + Y+L AV NH+G + GHYTA+ KN +
Sbjct: 786 YWRDKLDTVVEFPIRGLNMSEFVCNLSARPYVYDLIAVSNHYGAMGVGHYTAYAKNKL 843
>gi|109638751 ubiquitin specific protease 6 [Homo sapiens]
Length = 1406
Score = 92.8 bits (229), Expect = 4e-19
Identities = 56/187 (29%), Positives = 88/187 (47%), Gaps = 7/187 (3%)
Query: 38 PHFQGVTGLWNLGNTCCVNAISQCLCSILPLVEYFLTGKYITALQKFLLPSDCSEVATAF 97
P +G TGL NLGNTC +N+ QC+ + PL +YF++G+++ L + +A +
Sbjct: 526 PTEKGATGLSNLGNTCFMNSSIQCVSNTQPLTQYFISGRHLYELNRTNPIGMKGHMAKCY 585
Query: 98 AYLMTDMWLGDSDCVSPEIFWSALGNLYPAFTKKMQQDAQEFLICVLNELHEALKKYH-- 155
L+ ++W G V+P + P F QQD+QE L +L+ LHE L + H
Sbjct: 586 GDLVQELWSGTQKSVAPLKLRRTIAKYAPKFDGFQQQDSQELLAFLLDGLHEDLNRVHEK 645
Query: 156 --YSRRRSYEKGSTQRCCRKW---ITTETSIITQLFEEQLNYSIVCLKCEKCTYKNEVFT 210
+ S + + W + SII LF QL + C C + + + F
Sbjct: 646 PYVELKDSDGRPDWEVAAEAWDNHLRRNRSIIVDLFHGQLRSQVKCKTCGHISVRFDPFN 705
Query: 211 VFSLPIP 217
SLP+P
Sbjct: 706 FLSLPLP 712
Score = 35.4 bits (80), Expect = 0.073
Identities = 16/52 (30%), Positives = 27/52 (51%)
Query: 223 SLRDCLQCFFQQDALTWNNEIHCSFCETKQETAVRASISKAPKIIIFHLKRF 274
+L CL+ F ++ L + +CS C+T + + + P +I HLKRF
Sbjct: 1032 NLDSCLRAFTSEEELGESEMYYCSKCKTHCLATKKLDLWRLPPFLIIHLKRF 1083
Score = 33.1 bits (74), Expect = 0.36
Identities = 14/26 (53%), Positives = 16/26 (61%)
Query: 309 PKYNLCAVVNHFGDLDGGHYTAFCKN 334
P YNL A+ H G L GGHY + KN
Sbjct: 1310 PIYNLYAISCHSGILSGGHYITYAKN 1335
>gi|109134334 ubiquitin thiolesterase 44 [Homo sapiens]
Length = 712
Score = 92.4 bits (228), Expect = 5e-19
Identities = 81/274 (29%), Positives = 116/274 (42%), Gaps = 39/274 (14%)
Query: 90 CSEVATAFAYLMTDMWLGDSDCVSPEIFWSALGNLYPAFTKKMQQDAQEFLICVLNELHE 149
C E+ T F MW G VSP ++ L PAF QQDAQEFL +L+++
Sbjct: 382 CHELHTLFQV----MWSGKWALVSPFAMLHSVWRLIPAFRGYAQQDAQEFLCELLDKIQR 437
Query: 150 ALKKYHYSRRRSYEKGSTQRCCRKWITTETSIITQLFEEQLNYSIVCLKCEKCTYKNEVF 209
L+ S RK I +++ +F QL + CL C+ + E F
Sbjct: 438 ELETTGTSLPALIPTSQ-----RKLIKQVLNVVNNIFHGQLLSQVTCLACDNKSNTIEPF 492
Query: 210 TVFSLPIPSKYECSLRD----------CLQCFFQQDALTWNNEIHCSFCETKQ------- 252
SL P +Y+CS +D L F + +AL + C C +K+
Sbjct: 493 WDLSLEFPERYQCSGKDIASQPCLVTEMLAKFTETEALEGKIYV-CDQCNSKRRRFSSKP 551
Query: 253 ----ETAVRASISKAPKIIIFHLKRFDIQGTTKRKLRTDIHYPLTN-LDLTPYICSIFRK 307
E + I P+++ HLKRF G R+ + +H L++ PY C K
Sbjct: 552 VVLTEAQKQLMICHLPQVLRLHLKRFRWSGRNNRE-KIGVHVGFEEILNMEPYCCRETLK 610
Query: 308 YPK-----YNLCAVVNHFG-DLDGGHYTAFCKNS 335
+ Y+L AVV H G GHYTA+C NS
Sbjct: 611 SLRPECFIYDLSAVVMHHGKGFGSGHYTAYCYNS 644
>gi|109134332 ubiquitin thiolesterase 44 [Homo sapiens]
Length = 712
Score = 92.4 bits (228), Expect = 5e-19
Identities = 81/274 (29%), Positives = 116/274 (42%), Gaps = 39/274 (14%)
Query: 90 CSEVATAFAYLMTDMWLGDSDCVSPEIFWSALGNLYPAFTKKMQQDAQEFLICVLNELHE 149
C E+ T F MW G VSP ++ L PAF QQDAQEFL +L+++
Sbjct: 382 CHELHTLFQV----MWSGKWALVSPFAMLHSVWRLIPAFRGYAQQDAQEFLCELLDKIQR 437
Query: 150 ALKKYHYSRRRSYEKGSTQRCCRKWITTETSIITQLFEEQLNYSIVCLKCEKCTYKNEVF 209
L+ S RK I +++ +F QL + CL C+ + E F
Sbjct: 438 ELETTGTSLPALIPTSQ-----RKLIKQVLNVVNNIFHGQLLSQVTCLACDNKSNTIEPF 492
Query: 210 TVFSLPIPSKYECSLRD----------CLQCFFQQDALTWNNEIHCSFCETKQ------- 252
SL P +Y+CS +D L F + +AL + C C +K+
Sbjct: 493 WDLSLEFPERYQCSGKDIASQPCLVTEMLAKFTETEALEGKIYV-CDQCNSKRRRFSSKP 551
Query: 253 ----ETAVRASISKAPKIIIFHLKRFDIQGTTKRKLRTDIHYPLTN-LDLTPYICSIFRK 307
E + I P+++ HLKRF G R+ + +H L++ PY C K
Sbjct: 552 VVLTEAQKQLMICHLPQVLRLHLKRFRWSGRNNRE-KIGVHVGFEEILNMEPYCCRETLK 610
Query: 308 YPK-----YNLCAVVNHFG-DLDGGHYTAFCKNS 335
+ Y+L AVV H G GHYTA+C NS
Sbjct: 611 SLRPECFIYDLSAVVMHHGKGFGSGHYTAYCYNS 644
>gi|22550104 ubiquitin specific protease 32 [Homo sapiens]
Length = 1604
Score = 91.3 bits (225), Expect = 1e-18
Identities = 55/187 (29%), Positives = 88/187 (47%), Gaps = 7/187 (3%)
Query: 38 PHFQGVTGLWNLGNTCCVNAISQCLCSILPLVEYFLTGKYITALQKFLLPSDCSEVATAF 97
P +G TGL NLGNTC +N+ QC+ + PL +YF++G+++ L + +A +
Sbjct: 728 PTEKGATGLSNLGNTCFMNSSIQCVSNTQPLTQYFISGRHLYELNRTNPIGMKGHMAKCY 787
Query: 98 AYLMTDMWLGDSDCVSPEIFWSALGNLYPAFTKKMQQDAQEFLICVLNELHEALKKYH-- 155
L+ ++W G V+P + P F QQD+QE L +L+ LHE L + H
Sbjct: 788 GDLVQELWSGTQKNVAPLKLRWTIAKYAPRFNGFQQQDSQELLAFLLDGLHEDLNRVHEK 847
Query: 156 --YSRRRSYEKGSTQRCCRKW---ITTETSIITQLFEEQLNYSIVCLKCEKCTYKNEVFT 210
+ S + + W + SI+ LF QL + C C + + + F
Sbjct: 848 PYVELKDSDGRPDWEVAAEAWDNHLRRNRSIVVDLFHGQLRSQVKCKTCGHISVRFDPFN 907
Query: 211 VFSLPIP 217
SLP+P
Sbjct: 908 FLSLPLP 914
Score = 41.6 bits (96), Expect = 0.001
Identities = 21/79 (26%), Positives = 38/79 (48%)
Query: 223 SLRDCLQCFFQQDALTWNNEIHCSFCETKQETAVRASISKAPKIIIFHLKRFDIQGTTKR 282
+L CL+ F ++ L N +CS C+T + + + P I+I HLKRF
Sbjct: 1234 NLDSCLRAFTSEEELGENEMYYCSKCKTHCLATKKLDLWRLPPILIIHLKRFQFVNGRWI 1293
Query: 283 KLRTDIHYPLTNLDLTPYI 301
K + + +P + D + ++
Sbjct: 1294 KSQKIVKFPRESFDPSAFL 1312
Score = 33.1 bits (74), Expect = 0.36
Identities = 14/26 (53%), Positives = 16/26 (61%)
Query: 309 PKYNLCAVVNHFGDLDGGHYTAFCKN 334
P YNL A+ H G L GGHY + KN
Sbjct: 1508 PIYNLYAISCHSGILGGGHYVTYAKN 1533
>gi|21361749 ubiquitin thioesterase 49 [Homo sapiens]
Length = 640
Score = 89.0 bits (219), Expect = 6e-18
Identities = 80/282 (28%), Positives = 120/282 (42%), Gaps = 52/282 (18%)
Query: 90 CSEVATAFAYLMTDMWLGDSDCVSPEIFWSALGNLYPAFTKKMQQDAQEFLICVLNELHE 149
C E+ T F MW G VSP ++ +L PAF QQDAQEFL +L+++ +
Sbjct: 358 CRELHTLFRV----MWSGKWALVSPFAMLHSVWSLIPAFRGYDQQDAQEFLCELLHKVQQ 413
Query: 150 ALKKYHYSRRRSYEKGSTQRCC-----RKWITTETSIITQLFEEQLNYSIVCLKCEKCTY 204
L+ +G+T+R RK ++ +F QL + C+ C +
Sbjct: 414 ELE----------SEGTTRRILIPFSQRKLTKQVLKVVNTIFHGQLLSQVTCISCNYKSN 463
Query: 205 KNEVFTVFSLPIPSKY-------------ECSLRDCLQCFFQQDALTWNNEIHCSFCETK 251
E F SL P +Y EC L + L F + +AL C C +K
Sbjct: 464 TIEPFWDLSLEFPERYHCIEKGFVPLNQTECLLTEMLAKFTETEALE-GRIYACDQCNSK 522
Query: 252 Q-----------ETAVRASISKAPKIIIFHLKRFDIQGTTKRKLRTDIHYPLTN-LDLTP 299
+ E + I + P+++ HLKRF G R+ + +H L + P
Sbjct: 523 RRKSNPKPLVLSEARKQLMIYRLPQVLRLHLKRFRWSGRNHRE-KIGVHVVFDQVLTMEP 581
Query: 300 YIC-----SIFRKYPKYNLCAVVNHFG-DLDGGHYTAFCKNS 335
Y C S+ ++ Y+L AVV H G GHYTA+C N+
Sbjct: 582 YCCRDMLSSLDKETFAYDLSAVVMHHGKGFGSGHYTAYCYNT 623
Score = 35.8 bits (81), Expect = 0.056
Identities = 18/32 (56%), Positives = 21/32 (65%)
Query: 42 GVTGLWNLGNTCCVNAISQCLCSILPLVEYFL 73
GVTGL NLGNTC +N+I Q L + E FL
Sbjct: 251 GVTGLRNLGNTCYMNSILQVLSHLQKFRECFL 282
>gi|197116355 ubiquitin specific peptidase 46 isoform 2 [Homo
sapiens]
Length = 359
Score = 88.6 bits (218), Expect = 7e-18
Identities = 84/294 (28%), Positives = 125/294 (42%), Gaps = 13/294 (4%)
Query: 45 GLWNLGNTCCVNAISQCLCSILPLVEYFLTGKYITALQKFLLPSDCSEVATAFAYLMTDM 104
GL N GNTC N++ Q L P E L K ++ LL +A F + T
Sbjct: 29 GLVNFGNTCYCNSVLQALYFCRPFRENVLAYKAQQKKKENLLTC----LADLFHSIATQK 84
Query: 105 WLGDSDCVSPEIFWSALGNLYPAFTKKMQQDAQEFLICVLNELHEALKKYHYSRRRSYE- 163
+ P+ F S L F MQQDA EFL +LN + + L++ +++ +
Sbjct: 85 --KKVGVIPPKKFISRLRKENDLFDNYMQQDAHEFLNYLLNTIADILQEEKKQEKQNGKL 142
Query: 164 KGSTQRCCRKWITTETSIITQLFEEQLNYSIVCLKCEKCTYKNEVFTVFSLPIPSKYECS 223
K + E + + ++F+ L CL CE + K+E F S+ + + S
Sbjct: 143 KNGNMNEPAENNKPELTWVHEIFQGTLTNETRCLNCETVSSKDEDFLDLSVDV--EQNTS 200
Query: 224 LRDCLQCFFQQDALTWNNEIHCSFCETKQETAVRASISKAPKIIIFHLKRFDIQGTTKR- 282
+ CL+ F + L + +C C +KQE R + K P I+ HLKRF R
Sbjct: 201 ITHCLRDFSNTETLCSEQKYYCETCCSKQEAQKRMRVKKLPMILALHLKRFKYMEQLHRY 260
Query: 283 -KLRTDIHYPLTNLDLTPYICSIFRKYPKYNLCAVVNHFGD-LDGGHYTAFCKN 334
KL + +PL L L Y+L AVV H G + GHY K+
Sbjct: 261 TKLSYRVVFPL-ELRLFNTSSDAVNLDRMYDLVAVVVHCGSGPNRGHYITIVKS 313
>gi|31377709 ubiquitin specific peptidase 46 isoform 1 [Homo
sapiens]
Length = 366
Score = 88.6 bits (218), Expect = 7e-18
Identities = 84/294 (28%), Positives = 125/294 (42%), Gaps = 13/294 (4%)
Query: 45 GLWNLGNTCCVNAISQCLCSILPLVEYFLTGKYITALQKFLLPSDCSEVATAFAYLMTDM 104
GL N GNTC N++ Q L P E L K ++ LL +A F + T
Sbjct: 36 GLVNFGNTCYCNSVLQALYFCRPFRENVLAYKAQQKKKENLLTC----LADLFHSIATQK 91
Query: 105 WLGDSDCVSPEIFWSALGNLYPAFTKKMQQDAQEFLICVLNELHEALKKYHYSRRRSYE- 163
+ P+ F S L F MQQDA EFL +LN + + L++ +++ +
Sbjct: 92 --KKVGVIPPKKFISRLRKENDLFDNYMQQDAHEFLNYLLNTIADILQEEKKQEKQNGKL 149
Query: 164 KGSTQRCCRKWITTETSIITQLFEEQLNYSIVCLKCEKCTYKNEVFTVFSLPIPSKYECS 223
K + E + + ++F+ L CL CE + K+E F S+ + + S
Sbjct: 150 KNGNMNEPAENNKPELTWVHEIFQGTLTNETRCLNCETVSSKDEDFLDLSVDV--EQNTS 207
Query: 224 LRDCLQCFFQQDALTWNNEIHCSFCETKQETAVRASISKAPKIIIFHLKRFDIQGTTKR- 282
+ CL+ F + L + +C C +KQE R + K P I+ HLKRF R
Sbjct: 208 ITHCLRDFSNTETLCSEQKYYCETCCSKQEAQKRMRVKKLPMILALHLKRFKYMEQLHRY 267
Query: 283 -KLRTDIHYPLTNLDLTPYICSIFRKYPKYNLCAVVNHFGD-LDGGHYTAFCKN 334
KL + +PL L L Y+L AVV H G + GHY K+
Sbjct: 268 TKLSYRVVFPL-ELRLFNTSSDAVNLDRMYDLVAVVVHCGSGPNRGHYITIVKS 320
>gi|32698815 ubiquitin thiolesterase 12 [Homo sapiens]
Length = 370
Score = 88.2 bits (217), Expect = 1e-17
Identities = 84/295 (28%), Positives = 126/295 (42%), Gaps = 15/295 (5%)
Query: 45 GLWNLGNTCCVNAISQCLCSILPLVEYFLTGKYITALQKFLLPSDCSEVATAFAYLMTDM 104
GL N GNTC N++ Q L P E L K ++ LL +A F + T
Sbjct: 40 GLVNFGNTCYCNSVLQALYFCRPFREKVLAYKSQPRKKESLLTC----LADLFHSIATQK 95
Query: 105 WLGDSDCVSPEIFWSALGNLYPAFTKKMQQDAQEFLICVLNELHEALKKYHYSRRRS--Y 162
+ P+ F + L F MQQDA EFL +LN + + L++ +++
Sbjct: 96 --KKVGVIPPKKFITRLRKENELFDNYMQQDAHEFLNYLLNTIADILQEERKQEKQNGRL 153
Query: 163 EKGSTQRCCRKWITTETSIITQLFEEQLNYSIVCLKCEKCTYKNEVFTVFSLPIPSKYEC 222
G+ T + + + ++F+ L CL CE + K+E F S+ + +
Sbjct: 154 PNGNIDNENNN-STPDPTWVDEIFQGTLTNETRCLTCETISSKDEDFLDLSVDV--EQNT 210
Query: 223 SLRDCLQCFFQQDALTWNNEIHCSFCETKQETAVRASISKAPKIIIFHLKRFDIQGTTKR 282
S+ CL+ F + L + +C C +KQE R + K P I+ HLKRF R
Sbjct: 211 SITHCLRGFSNTETLCSEYKYYCEECRSKQEAHKRMKVKKLPMILALHLKRFKYMDQLHR 270
Query: 283 --KLRTDIHYPLTNLDLTPYICSIFRKYPKYNLCAVVNHFGD-LDGGHYTAFCKN 334
KL + +PL L L Y+L AVV H G + GHY A K+
Sbjct: 271 YTKLSYRVVFPL-ELRLFNTSGDATNPDRMYDLVAVVVHCGSGPNRGHYIAIVKS 324
>gi|120587027 ubiquitin specific peptidase 31 [Homo sapiens]
Length = 1352
Score = 87.4 bits (215), Expect = 2e-17
Identities = 45/137 (32%), Positives = 73/137 (53%), Gaps = 22/137 (16%)
Query: 222 CSLRDCLQCFFQQDALTWNNEIHCSFCETKQETAVRASISKAPKIIIFHLKRFDIQGTTK 281
C+L C Q + +++ L ++ C C+ Q+ ++ S+ P ++I HLKRF +G +
Sbjct: 596 CTLSQCFQLYTKEERLAPDDAWRCPHCKQLQQGSITLSLWTLPDVLIIHLKRFRQEGDRR 655
Query: 282 RKLRTDIHYPLTNLDLTPYICSIFR-------------------KYPK---YNLCAVVNH 319
KL+ + +PLT LD+TP++ + + P+ Y+L AV NH
Sbjct: 656 MKLQNMVKFPLTGLDMTPHVVKRSQSSWSLPSHWSPWRRPYGLGRDPEDYIYDLYAVCNH 715
Query: 320 FGDLDGGHYTAFCKNSV 336
G + GGHYTA+CKNSV
Sbjct: 716 HGTMQGGHYTAYCKNSV 732
Score = 61.2 bits (147), Expect = 1e-09
Identities = 54/201 (26%), Positives = 85/201 (42%), Gaps = 38/201 (18%)
Query: 42 GVTGLWNLGNTCCVNAISQCLCSILPLVEYFLTGKYITALQKFLLPS------------D 89
GV GL N GNTC +NA QCL + EY G+Y + PS
Sbjct: 126 GVAGLRNHGNTCFMNATLQCLSNTELFAEYLALGQYRAGRPE---PSPDPEQPAGRGAQG 182
Query: 90 CSEVATAFAYLMTDMWLGDSDCVSPEIFWSALGNLYPAFTKKMQQDAQEFLICVLNELHE 149
EV A+L+ +W + F + + + Q DAQEFL+ +L+ +HE
Sbjct: 183 QGEVTEQLAHLVRALWTLEYTPQHSRDFKTIVSKNALQYRGNSQHDAQEFLLWLLDRVHE 242
Query: 150 ALKKYHYSRRRSYE-------------KGSTQRCCRKWITTETSIITQLFEEQLNYSIVC 196
L ++S ++S + +G + C ++ + +LF+ Q S+ C
Sbjct: 243 DL---NHSVKQSGQPPLKPPSETDMMPEGPSFPVC-------STFVQELFQAQYRSSLTC 292
Query: 197 LKCEKCTYKNEVFTVFSLPIP 217
C+K + + F SLPIP
Sbjct: 293 PHCQKQSNTFDPFLCISLPIP 313
>gi|148612811 ubiquitin specific protease 43 [Homo sapiens]
Length = 1123
Score = 86.3 bits (212), Expect = 4e-17
Identities = 45/141 (31%), Positives = 74/141 (52%), Gaps = 23/141 (16%)
Query: 219 KYECSLRDCLQCFFQQDALTWNNEIHCSFCETKQETAVRASISKAPKIIIFHLKRFDIQG 278
++ C+L +C Q + +++ L ++ C C+ Q+ V+ S+ P I+I HLKRF G
Sbjct: 537 QHSCTLDECFQFYTKEEQLAQDDAWKCPHCQVLQQGMVKLSLWTLPDILIIHLKRFCQVG 596
Query: 279 TTKRKLRTDIHYPLTNLDLTPYICS--------------------IFRKYP---KYNLCA 315
+ KL T + +PL+ L++ P++ + YP Y+L A
Sbjct: 597 ERRNKLSTLVKFPLSGLNMAPHVAQRSTSPEAGLGPWPSWKQPDCLPTSYPLDFLYDLYA 656
Query: 316 VVNHFGDLDGGHYTAFCKNSV 336
V NH G+L GGHYTA+C+NS+
Sbjct: 657 VCNHHGNLQGGHYTAYCRNSL 677
Score = 68.6 bits (166), Expect = 8e-12
Identities = 57/196 (29%), Positives = 84/196 (42%), Gaps = 15/196 (7%)
Query: 28 LPVKEADGNQPHFQGVTGLWNLGNTCCVNAISQCLCSILPLVEYFLTGKYITALQKFLLP 87
L + DG +P G GL N GNTC +NA+ QCL + L E+ G+Y A +
Sbjct: 87 LQLPAGDGARP--PGAQGLKNHGNTCFMNAVVQCLSNTDLLAEFLALGRYRAAPGR---- 140
Query: 88 SDCSEVATAFAYLMTDMWLGDSDCVSPEIFWSALGNLYPAFTKKMQQDAQEFLICVLNEL 147
+EV A L+ +W + F +A+ F Q DA EFL+ +L+ +
Sbjct: 141 ---AEVTEQLAALVRALWTREYTPQLSAEFKNAVSKYGSQFQGNSQHDALEFLLWLLDRV 197
Query: 148 HEALK---KYHYSRRRSYEKGSTQRCC---RKWITTETSIITQLFEEQLNYSIVCLKCEK 201
HE L+ + S + E T C + S + F+ Q S+ C C K
Sbjct: 198 HEDLEGSSRGPVSEKLPPEATKTSENCLSPSAQLPLGQSFVQSHFQAQYRSSLTCPHCLK 257
Query: 202 CTYKNEVFTVFSLPIP 217
+ + F SLPIP
Sbjct: 258 QSNTFDPFLCVSLPIP 273
>gi|42516561 ubiquitin specific protease 33 isoform 3 [Homo sapiens]
Length = 828
Score = 84.7 bits (208), Expect = 1e-16
Identities = 52/202 (25%), Positives = 85/202 (42%), Gaps = 45/202 (22%)
Query: 180 SIITQLFEEQLNYSIVCLKCEKCTYKNEVFTVFSLPIPSKYECS---------------- 223
S+I+ +F+ + S+ CL C++ + E F SLPIP K + +
Sbjct: 473 SVISDIFDGTIISSVQCLTCDRVSVTLETFQDLSLPIPGKEDLAKLHSSSHPTSIVKAGS 532
Query: 224 ----------------------------LRDCLQCFFQQDALTWNNEIHCSFCETKQETA 255
L+DCL FF +D L +N C C+ +
Sbjct: 533 CGEAYAPQGWIAFFMEYVKSWFWGPVVTLQDCLAAFFARDELKGDNMYSCEKCKKLRNGV 592
Query: 256 VRASISKAPKIIIFHLKRFDIQGTTKRKLRTDIHYPLTNLDLTPYICSIF-RKYPKYNLC 314
+ P+I+ HLKRF + K+ T + +PL LDL P++ + Y+L
Sbjct: 593 KFCKVQNFPEILCIHLKRFRHELMFSTKISTHVSFPLEGLDLQPFLAKDSPAQIVTYDLL 652
Query: 315 AVVNHFGDLDGGHYTAFCKNSV 336
+V+ H G GHY A+C+N++
Sbjct: 653 SVICHHGTASSGHYIAYCRNNL 674
Score = 73.6 bits (179), Expect = 2e-13
Identities = 44/130 (33%), Positives = 70/130 (53%), Gaps = 7/130 (5%)
Query: 25 YDTLPVKEADGNQPHFQGVTGLWNLGNTCCVNAISQCLCSILPLVEYFLTGKYITALQKF 84
+D L ++ + ++ +G+TGL N+GNTC +NA Q L + PL ++FL + K
Sbjct: 166 FDDLDIEADEEDELRARGLTGLKNIGNTCYMNAALQALSNCPPLTQFFLDCGGLARTDK- 224
Query: 85 LLPSDCSEVATAFAYLMTDMW-LGDSDCVSPEIFWSALGNLYPAFTKKMQQDAQEFLICV 143
P+ C ++ LMT++W V P + + + P F QQDAQEFL C+
Sbjct: 225 -KPAICK----SYLKLMTELWHKSRPGSVVPTTLFQGIKTVNPTFRGYSQQDAQEFLRCL 279
Query: 144 LNELHEALKK 153
++ LHE LK+
Sbjct: 280 MDLLHEELKE 289
>gi|24234683 ubiquitin specific peptidase 11 [Homo sapiens]
Length = 963
Score = 84.0 bits (206), Expect = 2e-16
Identities = 55/191 (28%), Positives = 88/191 (46%), Gaps = 15/191 (7%)
Query: 42 GVTGLWNLGNTCCVNAISQCLCSILPLVEYFLTGKYITALQKFLLPSDC-SEVATAFAYL 100
G+ GL NLGNTC +N+ QCL ++ L EYFL Y+ L F P E+A A+A L
Sbjct: 307 GICGLTNLGNTCFMNSALQCLSNVPQLTEYFLNNCYLEEL-NFRNPLGMKGEIAEAYADL 365
Query: 101 MTDMWLGDSDCVSPEIFWSALGNLYPAFTKKMQQDAQEFLICVLNELHEALKKYHYSRRR 160
+ W G + P +F + +G+ F Q D+QE L +L+ LHE L + +++
Sbjct: 366 VKQAWSGHHRSIVPHVFKNKVGHFASQFLGYQQHDSQELLSFLLDGLHEDLNRV---KKK 422
Query: 161 SY----------EKGSTQRCCRKWITTETSIITQLFEEQLNYSIVCLKCEKCTYKNEVFT 210
Y ++ Q + S+I F ++VC C + + F
Sbjct: 423 EYVELCDAAGRPDQEVAQEAWQNHKRRNDSVIVDTFHGLFKSTLVCPDCGNVSVTFDPFC 482
Query: 211 VFSLPIPSKYE 221
S+P+P ++
Sbjct: 483 YLSVPLPISHK 493
Score = 71.6 bits (174), Expect = 9e-13
Identities = 37/123 (30%), Positives = 62/123 (50%), Gaps = 4/123 (3%)
Query: 216 IPSKYECSLRDCLQCFFQQDALTWNNEIHCSFCETKQETAVRASISKAPKIIIFHLKRFD 275
+ K L++C++ F + L N +C C+ Q + + P+I+I HLKRF
Sbjct: 773 VMKKAPVRLQECIELFTTVETLEKENPWYCPSCKQHQLATKKLDLWMLPEILIIHLKRFS 832
Query: 276 IQGTTKRKLRTDIHYPLTNLDLTPYICSIFR----KYPKYNLCAVVNHFGDLDGGHYTAF 331
++ KL T + +P+ +LD + ++ + KY+L AV NH+G + GHYT F
Sbjct: 833 YTKFSREKLDTLVEFPIRDLDFSEFVIQPQNESNPELYKYDLIAVSNHYGGMRDGHYTTF 892
Query: 332 CKN 334
N
Sbjct: 893 ACN 895
>gi|79750944 ubiquitin specific peptidase 42 [Homo sapiens]
Length = 1316
Score = 82.8 bits (203), Expect = 4e-16
Identities = 80/300 (26%), Positives = 124/300 (41%), Gaps = 26/300 (8%)
Query: 37 QPHFQGVTGLWNLGNTCCVNAISQCLCSILPLVEYFLTGKYITALQKFLLPSDCSEVATA 96
Q H G GL NLGNTC NA QCL PL Y L+ ++ K + T
Sbjct: 105 QTHRVGA-GLQNLGNTCFANAALQCLTYTPPLANYMLSHEH----SKTCHAEGFCMMCTM 159
Query: 97 FAYLMTDMWLGDSDCVSPEIFWSALGNLYPAFTKKMQQDAQEFLICVLNELHEALKKYHY 156
A++ T D + P + + + F Q+DA EFL ++ + +A
Sbjct: 160 QAHI-TQALSNPGDVIKPMFVINEMRRIARHFRFGNQEDAHEFLQYTVDAMQKACLNGSN 218
Query: 157 SRRRSYEKGSTQRCCRKWITTETSIITQLFEEQLNYSIVCLKCEKCTYKNEVFTVFSLPI 216
R T T+++ Q+F L + CL C+ + + + +L I
Sbjct: 219 KLDRH--------------TQATTLVCQIFGGYLRSRVKCLNCKGVSDTFDPYLDITLEI 264
Query: 217 PSKYECSLRDCLQCFFQQDALTWNNEIHCSFCETKQETAVRASISKAPKIIIFHLKRFDI 276
K S+ L+ F + + L N CS C+ + R +I ++ ++ LKRF
Sbjct: 265 --KAAQSVNKALEQFVKPEQLDGENSYKCSKCKKMVPASKRFTIHRSSNVLTLSLKRF-- 320
Query: 277 QGTTKRKLRTDIHYPLTNLDLTPYICSIFRKYPKYNLCAVVNHFG-DLDGGHYTAFCKNS 335
T K+ D+ YP LD+ PY+ + Y L AV+ H G + GHY + K S
Sbjct: 321 ANFTGGKIAKDVKYP-EYLDIRPYMSQPNGEPIVYVLYAVLVHTGFNCHAGHYFCYIKAS 379
>gi|42516567 ubiquitin specific protease 33 isoform 1 [Homo sapiens]
Length = 942
Score = 81.6 bits (200), Expect = 9e-16
Identities = 52/210 (24%), Positives = 85/210 (40%), Gaps = 53/210 (25%)
Query: 180 SIITQLFEEQLNYSIVCLKCEKCTYKNEVFTVFSLPIPSKYECS---------------- 223
S+I+ +F+ + S+ CL C++ + E F SLPIP K + +
Sbjct: 473 SVISDIFDGTIISSVQCLTCDRVSVTLETFQDLSLPIPGKEDLAKLHSSSHPTSIVKAGS 532
Query: 224 ------------------------------------LRDCLQCFFQQDALTWNNEIHCSF 247
L+DCL FF +D L +N C
Sbjct: 533 CGEAYAPQGWIAFFMEYVKRFVVSCVPSWFWGPVVTLQDCLAAFFARDELKGDNMYSCEK 592
Query: 248 CETKQETAVRASISKAPKIIIFHLKRFDIQGTTKRKLRTDIHYPLTNLDLTPYICSIF-R 306
C+ + + P+I+ HLKRF + K+ T + +PL LDL P++
Sbjct: 593 CKKLRNGVKFCKVQNFPEILCIHLKRFRHELMFSTKISTHVSFPLEGLDLQPFLAKDSPA 652
Query: 307 KYPKYNLCAVVNHFGDLDGGHYTAFCKNSV 336
+ Y+L +V+ H G GHY A+C+N++
Sbjct: 653 QIVTYDLLSVICHHGTASSGHYIAYCRNNL 682
Score = 73.6 bits (179), Expect = 2e-13
Identities = 44/130 (33%), Positives = 70/130 (53%), Gaps = 7/130 (5%)
Query: 25 YDTLPVKEADGNQPHFQGVTGLWNLGNTCCVNAISQCLCSILPLVEYFLTGKYITALQKF 84
+D L ++ + ++ +G+TGL N+GNTC +NA Q L + PL ++FL + K
Sbjct: 166 FDDLDIEADEEDELRARGLTGLKNIGNTCYMNAALQALSNCPPLTQFFLDCGGLARTDK- 224
Query: 85 LLPSDCSEVATAFAYLMTDMW-LGDSDCVSPEIFWSALGNLYPAFTKKMQQDAQEFLICV 143
P+ C ++ LMT++W V P + + + P F QQDAQEFL C+
Sbjct: 225 -KPAICK----SYLKLMTELWHKSRPGSVVPTTLFQGIKTVNPTFRGYSQQDAQEFLRCL 279
Query: 144 LNELHEALKK 153
++ LHE LK+
Sbjct: 280 MDLLHEELKE 289
>gi|42516565 ubiquitin specific protease 33 isoform 2 [Homo sapiens]
Length = 911
Score = 81.6 bits (200), Expect = 9e-16
Identities = 52/210 (24%), Positives = 85/210 (40%), Gaps = 53/210 (25%)
Query: 180 SIITQLFEEQLNYSIVCLKCEKCTYKNEVFTVFSLPIPSKYECS---------------- 223
S+I+ +F+ + S+ CL C++ + E F SLPIP K + +
Sbjct: 442 SVISDIFDGTIISSVQCLTCDRVSVTLETFQDLSLPIPGKEDLAKLHSSSHPTSIVKAGS 501
Query: 224 ------------------------------------LRDCLQCFFQQDALTWNNEIHCSF 247
L+DCL FF +D L +N C
Sbjct: 502 CGEAYAPQGWIAFFMEYVKRFVVSCVPSWFWGPVVTLQDCLAAFFARDELKGDNMYSCEK 561
Query: 248 CETKQETAVRASISKAPKIIIFHLKRFDIQGTTKRKLRTDIHYPLTNLDLTPYICSIF-R 306
C+ + + P+I+ HLKRF + K+ T + +PL LDL P++
Sbjct: 562 CKKLRNGVKFCKVQNFPEILCIHLKRFRHELMFSTKISTHVSFPLEGLDLQPFLAKDSPA 621
Query: 307 KYPKYNLCAVVNHFGDLDGGHYTAFCKNSV 336
+ Y+L +V+ H G GHY A+C+N++
Sbjct: 622 QIVTYDLLSVICHHGTASSGHYIAYCRNNL 651
Score = 73.6 bits (179), Expect = 2e-13
Identities = 44/130 (33%), Positives = 70/130 (53%), Gaps = 7/130 (5%)
Query: 25 YDTLPVKEADGNQPHFQGVTGLWNLGNTCCVNAISQCLCSILPLVEYFLTGKYITALQKF 84
+D L ++ + ++ +G+TGL N+GNTC +NA Q L + PL ++FL + K
Sbjct: 135 FDDLDIEADEEDELRARGLTGLKNIGNTCYMNAALQALSNCPPLTQFFLDCGGLARTDK- 193
Query: 85 LLPSDCSEVATAFAYLMTDMW-LGDSDCVSPEIFWSALGNLYPAFTKKMQQDAQEFLICV 143
P+ C ++ LMT++W V P + + + P F QQDAQEFL C+
Sbjct: 194 -KPAICK----SYLKLMTELWHKSRPGSVVPTTLFQGIKTVNPTFRGYSQQDAQEFLRCL 248
Query: 144 LNELHEALKK 153
++ LHE LK+
Sbjct: 249 MDLLHEELKE 258
Database: hs.faa
Posted date: Aug 4, 2009 4:42 PM
Number of letters in database: 18,247,518
Number of sequences in database: 37,866
Lambda K H
0.324 0.137 0.442
Gapped
Lambda K H
0.267 0.0410 0.140
Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Hits to DB: 13,588,619
Number of Sequences: 37866
Number of extensions: 610757
Number of successful extensions: 2018
Number of sequences better than 10.0: 30
Number of HSP's better than 10.0 without gapping: 101
Number of HSP's successfully gapped in prelim test: 28
Number of HSP's that attempted gapping in prelim test: 1650
Number of HSP's gapped (non-prelim): 230
length of query: 339
length of database: 18,247,518
effective HSP length: 103
effective length of query: 236
effective length of database: 14,347,320
effective search space: 3385967520
effective search space used: 3385967520
T: 11
A: 40
X1: 15 ( 7.0 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 40 (21.6 bits)
S2: 62 (28.5 bits)
Search results were obtained with NCBI BLAST and RefSeq entries.
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Guide to the Human Genome
Copyright © 2010 by Stewart Scherer. All rights reserved.