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Search of human proteins with 4507483
BLASTP 2.2.11 [Jun-05-2005]
Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer,
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997),
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs", Nucleic Acids Res. 25:3389-3402.
Query= gi|4507483 thrombomodulin precursor [Homo sapiens]
(575 letters)
Database: hs.faa
37,866 sequences; 18,247,518 total letters
Searching..................................................done
Score E
Sequences producing significant alignments: (bits) Value
gi|4507483 thrombomodulin precursor [Homo sapiens] 1239 0.0
gi|9966885 tumor endothelial marker 1 precursor [Homo sapiens] 213 5e-55
gi|88758613 CD93 antigen precursor [Homo sapiens] 198 1e-50
gi|110347457 EGF-like-domain, multiple 3 [Homo sapiens] 132 7e-31
gi|66346695 fibrillin 2 precursor [Homo sapiens] 130 3e-30
gi|62548862 matrilin 2 isoform b precursor [Homo sapiens] 129 1e-29
gi|62548860 matrilin 2 isoform a precursor [Homo sapiens] 129 1e-29
gi|24430141 fibrillin 1 precursor [Homo sapiens] 125 8e-29
gi|56237021 fibrillin 3 precursor [Homo sapiens] 121 2e-27
gi|118572606 hemicentin 1 [Homo sapiens] 120 3e-27
gi|51873053 fibulin 2 isoform a precursor [Homo sapiens] 119 1e-26
gi|31377568 signal peptide, CUB domain, EGF-like 3 [Homo sapiens] 117 3e-26
gi|120587029 signal peptide, CUB domain, EGF-like 1 [Homo sapiens] 116 5e-26
gi|51873055 fibulin 2 isoform b precursor [Homo sapiens] 115 1e-25
gi|34734064 fibulin 1 isoform B precursor [Homo sapiens] 113 5e-25
gi|34734068 fibulin 1 isoform A precursor [Homo sapiens] 113 5e-25
gi|34734066 fibulin 1 isoform D [Homo sapiens] 113 5e-25
gi|34734062 fibulin 1 isoform C precursor [Homo sapiens] 113 5e-25
gi|46249414 latent transforming growth factor beta binding prote... 112 1e-24
gi|46249412 latent transforming growth factor beta binding prote... 112 1e-24
gi|194328809 latent transforming growth factor beta binding prot... 110 3e-24
gi|18497288 latent transforming growth factor beta binding prote... 110 3e-24
gi|110347437 latent transforming growth factor beta binding prot... 106 7e-23
gi|110347412 latent transforming growth factor beta binding prot... 106 7e-23
gi|110347431 latent transforming growth factor beta binding prot... 106 7e-23
gi|190343004 EGF-containing fibulin-like extracellular matrix pr... 105 9e-23
gi|169178458 PREDICTED: hemicentin 2 [Homo sapiens] 104 3e-22
gi|239749684 PREDICTED: hemicentin 2 [Homo sapiens] 104 3e-22
gi|169177000 PREDICTED: hemicentin 2 [Homo sapiens] 104 3e-22
gi|4557733 latent transforming growth factor beta binding protei... 102 7e-22
>gi|4507483 thrombomodulin precursor [Homo sapiens]
Length = 575
Score = 1239 bits (3207), Expect = 0.0
Identities = 575/575 (100%), Positives = 575/575 (100%)
Query: 1 MLGVLVLGALALAGLGFPAPAEPQPGGSQCVEHDCFALYPGPATFLNASQICDGLRGHLM 60
MLGVLVLGALALAGLGFPAPAEPQPGGSQCVEHDCFALYPGPATFLNASQICDGLRGHLM
Sbjct: 1 MLGVLVLGALALAGLGFPAPAEPQPGGSQCVEHDCFALYPGPATFLNASQICDGLRGHLM 60
Query: 61 TVRSSVAADVISLLLNGDGGVGRRRLWIGLQLPPGCGDPKRLGPLRGFQWVTGDNNTSYS 120
TVRSSVAADVISLLLNGDGGVGRRRLWIGLQLPPGCGDPKRLGPLRGFQWVTGDNNTSYS
Sbjct: 61 TVRSSVAADVISLLLNGDGGVGRRRLWIGLQLPPGCGDPKRLGPLRGFQWVTGDNNTSYS 120
Query: 121 RWARLDLNGAPLCGPLCVAVSAAEATVPSEPIWEEQQCEVKADGFLCEFHFPATCRPLAV 180
RWARLDLNGAPLCGPLCVAVSAAEATVPSEPIWEEQQCEVKADGFLCEFHFPATCRPLAV
Sbjct: 121 RWARLDLNGAPLCGPLCVAVSAAEATVPSEPIWEEQQCEVKADGFLCEFHFPATCRPLAV 180
Query: 181 EPGAAAAAVSITYGTPFAARGADFQALPVGSSAAVAPLGLQLMCTAPPGAVQGHWAREAP 240
EPGAAAAAVSITYGTPFAARGADFQALPVGSSAAVAPLGLQLMCTAPPGAVQGHWAREAP
Sbjct: 181 EPGAAAAAVSITYGTPFAARGADFQALPVGSSAAVAPLGLQLMCTAPPGAVQGHWAREAP 240
Query: 241 GAWDCSVENGGCEHACNAIPGAPRCQCPAGAALQADGRSCTASATQSCNDLCEHFCVPNP 300
GAWDCSVENGGCEHACNAIPGAPRCQCPAGAALQADGRSCTASATQSCNDLCEHFCVPNP
Sbjct: 241 GAWDCSVENGGCEHACNAIPGAPRCQCPAGAALQADGRSCTASATQSCNDLCEHFCVPNP 300
Query: 301 DQPGSYSCMCETGYRLAADQHRCEDVDDCILEPSPCPQRCVNTQGGFECHCYPNYDLVDG 360
DQPGSYSCMCETGYRLAADQHRCEDVDDCILEPSPCPQRCVNTQGGFECHCYPNYDLVDG
Sbjct: 301 DQPGSYSCMCETGYRLAADQHRCEDVDDCILEPSPCPQRCVNTQGGFECHCYPNYDLVDG 360
Query: 361 ECVEPVDPCFRANCEYQCQPLNQTSYLCVCAEGFAPIPHEPHRCQMFCNQTACPADCDPN 420
ECVEPVDPCFRANCEYQCQPLNQTSYLCVCAEGFAPIPHEPHRCQMFCNQTACPADCDPN
Sbjct: 361 ECVEPVDPCFRANCEYQCQPLNQTSYLCVCAEGFAPIPHEPHRCQMFCNQTACPADCDPN 420
Query: 421 TQASCECPEGYILDDGFICTDIDECENGGFCSGVCHNLPGTFECICGPDSALARHIGTDC 480
TQASCECPEGYILDDGFICTDIDECENGGFCSGVCHNLPGTFECICGPDSALARHIGTDC
Sbjct: 421 TQASCECPEGYILDDGFICTDIDECENGGFCSGVCHNLPGTFECICGPDSALARHIGTDC 480
Query: 481 DSGKVDGGDSGSGEPPPSPTPGSTLTPPAVGLVHSGLLIGISIASLCLVVALLALLCHLR 540
DSGKVDGGDSGSGEPPPSPTPGSTLTPPAVGLVHSGLLIGISIASLCLVVALLALLCHLR
Sbjct: 481 DSGKVDGGDSGSGEPPPSPTPGSTLTPPAVGLVHSGLLIGISIASLCLVVALLALLCHLR 540
Query: 541 KKQGAARAKMEYKCAAPSKEVVLQHVRTERTPQRL 575
KKQGAARAKMEYKCAAPSKEVVLQHVRTERTPQRL
Sbjct: 541 KKQGAARAKMEYKCAAPSKEVVLQHVRTERTPQRL 575
>gi|9966885 tumor endothelial marker 1 precursor [Homo sapiens]
Length = 757
Score = 213 bits (541), Expect = 5e-55
Identities = 147/375 (39%), Positives = 184/375 (49%), Gaps = 34/375 (9%)
Query: 1 MLGVLVLGALALAGLGF-PAPAEPQPGGSQCVEHDCFALYPGPATFLNASQICDGLRGHL 59
+L +L+ A A LG P AEP+ + C C+AL+P TFL A + C L G L
Sbjct: 2 LLRLLLAWAAAGPTLGQDPWAAEPR---AACGPSSCYALFPRRRTFLEAWRACRELGGDL 58
Query: 60 MTVRSSVAADVISLLLNGDGGVGRRRLWIGLQLPPGCGDPKRLGPLRGFQWVTGDNNTSY 119
T R+ A + L+ G R LWIGLQ +R PLRGF W TGD +T++
Sbjct: 59 ATPRTPEEAQRVDSLVGA--GPASRLLWIGLQRQARQCQLQR--PLRGFTWTTGDQDTAF 114
Query: 120 SRWARLDLNGAPLCGPLCVAVSAAEATVPSEPIWEEQQCEVKADGFLCEFHFPATCRPLA 179
+ WA+ +G P CVA+ A+ E W E C + DG+LC+F F C L
Sbjct: 115 TNWAQ-PASGGPCPAQRCVALEAS-----GEHRWLEGSCTLAVDGYLCQFGFEGACPALQ 168
Query: 180 VEPGAAAAAVSITYGTPFAARGADFQALPVGSSAAV---APLGLQLMCTAPPGAVQGHWA 236
E G A AV Y TPF +F+ LP GS AAV A G L+C P G W+
Sbjct: 169 DEAGQAGPAV---YTTPFHLVSTEFEWLPFGSVAAVQCQAGRGASLLCVKQPEGGVG-WS 224
Query: 237 REAP--GAWDCSVENGGCEHAC-NAIPGAPRCQCPAGAALQADGRSCTASATQS-CNDLC 292
R P CS +NGGCEH C + G C+C G L ADGRSC Q+ C C
Sbjct: 225 RAGPLCLGTGCSPDNGGCEHECVEEVDGHVSCRCTEGFRLAADGRSCEDPCAQAPCEQQC 284
Query: 293 EHFCVPNPDQPGSYSCMCETGYRLAADQ-HRCEDVDDCILEPSPCPQRCVNTQGGFECHC 351
E P P YSC C G+R A D HRC D D+C + C Q CVN GGFEC+C
Sbjct: 285 E------PGGPQGYSCHCRLGFRPAEDDPHRCVDTDECQI-AGVCQQMCVNYVGGFECYC 337
Query: 352 YPNYDL-VDGECVEP 365
++L DG P
Sbjct: 338 SEGHELEADGISCSP 352
Score = 63.9 bits (154), Expect = 4e-10
Identities = 34/97 (35%), Positives = 43/97 (44%), Gaps = 5/97 (5%)
Query: 374 CEYQCQPLNQTSYLCVCAEGFAPIPHEPHRCQMFCNQTACPADCDPNTQA--SCECPEGY 431
CE++C C C EGF + + C+ C Q C C+P SC C G+
Sbjct: 242 CEHECVEEVDGHVSCRCTEGFR-LAADGRSCEDPCAQAPCEQQCEPGGPQGYSCHCRLGF 300
Query: 432 --ILDDGFICTDIDECENGGFCSGVCHNLPGTFECIC 466
DD C D DEC+ G C +C N G FEC C
Sbjct: 301 RPAEDDPHRCVDTDECQIAGVCQQMCVNYVGGFECYC 337
>gi|88758613 CD93 antigen precursor [Homo sapiens]
Length = 652
Score = 198 bits (503), Expect = 1e-50
Identities = 172/557 (30%), Positives = 233/557 (41%), Gaps = 103/557 (18%)
Query: 2 LGVLVLGALALAGLGFPAPAEPQPGGSQCVEHDCFALYPGPATFLNASQICDGLRGHLMT 61
+G+L+L L L G A+ + CV C+ + G + A C+ G+L T
Sbjct: 5 MGLLLLLLLLLTQPGAGTGADTE--AVVCVGTACYTAHSGKLSAAEAQNHCNQNGGNLAT 62
Query: 62 VRSSVAAD----VISLLLNGDGGVGRR--RLWIGLQLPPG-CGDPKRLGPLRGFQWVTGD 114
V+S A V++ LL + + R + WIGLQ G C DP PL+GF WV G
Sbjct: 63 VKSKEEAQHVQRVLAQLLRREAALTARMSKFWIGLQREKGKCLDPSL--PLKGFSWVGGG 120
Query: 115 NNTSYSRWARLDLNGAPLCGPLCVAVSAAEATVPSE-PIWEEQQCEVKA------DGFLC 167
+T YS W + N + + + ++ +PS P W E C +GF+C
Sbjct: 121 EDTPYSNWHKELRNSCISKRCVSLLLDLSQPLLPSRLPKWSEGPCGSPGSPGSNIEGFVC 180
Query: 168 EFHFPATCRPLAVE-PGAAAAAVSITYGTPFAARGADFQALPVGSSAAVAPLGLQLMC-T 225
+F F CRPLA+ PG +TY TPF + +A+P S+A VA C
Sbjct: 181 KFSFKGMCRPLALGGPG------QVTYTTPFQTTSSSLEAVPFASAANVA-------CGE 227
Query: 226 APPGAVQGHW---AREAPGAWD--------------CSVENGGCEHAC-NAIPGAPRCQC 267
Q H+ +AP +D C+ NGGC C G+ C C
Sbjct: 228 GDKDETQSHYFLCKEKAPDVFDWGSSGPLCVSPKYGCNFNNGGCHQDCFEGGDGSFLCGC 287
Query: 268 PAGAALQADGRSCTASATQSCNDLCEH--FCVPNPDQPGSYSCMCETGYRLAADQHRCED 325
G L D +C AS + C CV P +Y+C C GY+L + Q C D
Sbjct: 288 RPGFRLLDDLVTC-ASRNPCSSSPCRGGATCVLGPHGK-NYTCRCPQGYQLDSSQLDCVD 345
Query: 326 VDDCILEPSPCPQRCVNTQGGFECHCYPNYDLVDGECVEPVDPCFRANCEYQCQPLNQTS 385
VD+C + SPC Q CVNT GGF C C+ Y EP P E CQ +++
Sbjct: 346 VDEC--QDSPCAQECVNTPGGFRCECWVGY--------EPGGP-----GEGACQDVDE-- 388
Query: 386 YLCVCAEGFAPIPHEPHRCQMFCNQTACPADCDPNTQASCECPEGYIL--DDGFICTDID 443
CA G +P C C T + C C EGY+L +DG C D+D
Sbjct: 389 ----CALGRSP-------CAQGCTNT--------DGSFHCSCEEGYVLAGEDGTQCQDVD 429
Query: 444 EC--ENGGFCSGVCHNLPGTFECICGPDSALARHIGTDCDSGKVDGG-------DSGSGE 494
EC G C +C N G+F C C P LA + G C G V G + GE
Sbjct: 430 ECVGPGGPLCDSLCFNTQGSFHCGCLPGWVLAPN-GVSCTMGPVSLGPPSGPPDEEDKGE 488
Query: 495 PPPSPTPGSTLTPPAVG 511
S P + P G
Sbjct: 489 KEGSTVPRAATASPTRG 505
>gi|110347457 EGF-like-domain, multiple 3 [Homo sapiens]
Length = 1541
Score = 132 bits (333), Expect = 7e-31
Identities = 91/260 (35%), Positives = 117/260 (45%), Gaps = 21/260 (8%)
Query: 223 MCTAPPGAVQGHWAREAPGAWDCSVENGGCEHACNAIP-GAPRCQCPAGAALQADGRSCT 281
+C PG +R C++ NGGC+H C + RCQC G LQ DGR C
Sbjct: 184 LCECKPGFRLHTDSRTCLAINSCALGNGGCQHHCVQLTITRHRCQCRPGFQLQEDGRHCV 243
Query: 282 A-SATQSCNDLCEHFCVPNPDQPGSYSCMCETGYRLAADQHRCEDVDDCILEPSPCPQRC 340
S + N C H C G C C GY+LAAD CEDVD+C + C C
Sbjct: 244 RRSPCANRNGSCMHRCQV---VRGLARCECHVGYQLAADGKACEDVDECAAGLAQCAHGC 300
Query: 341 VNTQGGFECHCYPNYDL-VDG-EC----VEPVDPCFRAN--CEYQCQPLNQTSYLCVCAE 392
+NTQG F+C C+ Y+L DG +C +E V+ C N C + C LC C
Sbjct: 301 LNTQGSFKCVCHAGYELGADGRQCYRIEMEIVNSCEANNGGCSHGCSH-TSAGPLCTCPR 359
Query: 393 GFAPIPHEPHRC---QMFCNQTACPADCDPNTQA-SCECPEGYILD-DGFICTDIDECEN 447
G+ + + C + C C N C C GY L DG C D+DEC +
Sbjct: 360 GY-ELDTDQRTCIDVDDCADSPCCQQVCTNNPGGYECGCYAGYRLSADGCGCEDVDECAS 418
Query: 448 G-GFCSGVCHNLPGTFECIC 466
G C C NL G+F+C C
Sbjct: 419 SRGGCEHHCTNLAGSFQCSC 438
Score = 130 bits (327), Expect = 3e-30
Identities = 91/261 (34%), Positives = 114/261 (43%), Gaps = 28/261 (10%)
Query: 224 CTAPPGAVQGHWAREAPGAWDCSVENGGCEHACNAIPGAPRCQCPAGAALQADGRSCTAS 283
C PPG QG R +C NGGC+H C PG+ C+C G L D R+C
Sbjct: 147 CHCPPG-FQG--PRCQYDVDECRTHNGGCQHRCVNTPGSYLCECKPGFRLHTDSRTCL-- 201
Query: 284 ATQSC---NDLCEHFCVPNPDQPGSYSCMCETGYRLAADQHRCEDVDDCILEPSPCPQRC 340
A SC N C+H CV + C C G++L D C C C RC
Sbjct: 202 AINSCALGNGGCQHHCVQLTIT--RHRCQCRPGFQLQEDGRHCVRRSPCANRNGSCMHRC 259
Query: 341 VNTQGGFECHCYPNYDL-VDGECVEPVDPCFR--ANCEYQCQPLN-QTSYLCVCAEGF-- 394
+G C C+ Y L DG+ E VD C A C + C LN Q S+ CVC G+
Sbjct: 260 QVVRGLARCECHVGYQLAADGKACEDVDECAAGLAQCAHGC--LNTQGSFKCVCHAGYEL 317
Query: 395 APIPHEPHRCQM------FCNQTACPADCDPNTQAS--CECPEGYILD-DGFICTDIDEC 445
+ +R +M N C C +T A C CP GY LD D C D+D+C
Sbjct: 318 GADGRQCYRIEMEIVNSCEANNGGCSHGCS-HTSAGPLCTCPRGYELDTDQRTCIDVDDC 376
Query: 446 ENGGFCSGVCHNLPGTFECIC 466
+ C VC N PG +EC C
Sbjct: 377 ADSPCCQQVCTNNPGGYECGC 397
Score = 109 bits (272), Expect = 8e-24
Identities = 79/281 (28%), Positives = 102/281 (36%), Gaps = 60/281 (21%)
Query: 245 CSVENGGCEHACNAIPGAPRCQCPAGAALQADGRSCTASATQSCNDLCEHFCVPNPDQPG 304
C NGGC H C+ P C CP G L D R+C + + C+ C NP G
Sbjct: 335 CEANNGGCSHGCSHTSAGPLCTCPRGYELDTDQRTCIDVDDCADSPCCQQVCTNNP---G 391
Query: 305 SYSCMCETGYRLAADQHRCEDVDDCILEPSPCPQRCVNTQGGFECHCYPNYDLVDGE--C 362
Y C C GYRL+AD CEDVD+C C C N G F+C C Y L + C
Sbjct: 392 GYECGCYAGYRLSADGCGCEDVDECASSRGGCEHHCTNLAGSFQCSCEAGYRLHEDRRGC 451
Query: 363 VEPVDPCFRANCEYQ-CQPLNQTSYL-------------------------CVCAEGFAP 396
+P + E +PL + L E F
Sbjct: 452 SPLEEPMVDLDGELPFVRPLPHIAVLQDELPQLFQDDDVGADEEEAELRGEHTLTEKFVC 511
Query: 397 IPHE-PHRCQMFCNQTACPADCDPNTQASCECPEGYILDDGFICTDI------------- 442
+ H C + C+ C C+CPEG+ G IC +
Sbjct: 512 LDDSFGHDCSLTCDDCRNGGTCLLGLD-GCDCPEGW---TGLICNETCPPDTFGKNCSFS 567
Query: 443 DECENGGFCSGVCHNLPGTFECICGPDSALARHIGTDCDSG 483
C+NGG C V T C C P + GT+C+ G
Sbjct: 568 CSCQNGGTCDSV------TGACRCPPGVS-----GTNCEDG 597
Score = 57.4 bits (137), Expect = 4e-08
Identities = 91/359 (25%), Positives = 113/359 (31%), Gaps = 86/359 (23%)
Query: 167 CEFHF--PATCRPLAVEPGAAAAAVSITYGT--PFAARGADF-QALPVGS---------S 212
CE + P + G A +VS G P +G D Q PVG+ S
Sbjct: 686 CELGYFGPGCWQACTCPVGVACDSVSGECGKRCPAGFQGEDCGQECPVGTFGVNCSSSCS 745
Query: 213 AAVAPL-GLQLMCTAPPGAVQGHWAREAP-GAWDCSVENGGCEHACNAIPGAPRCQCPAG 270
AP G+ C PPG + P G W GC+ C A A RC G
Sbjct: 746 CGGAPCHGVTGQCRCPPGRTGEDCEADCPEGRWGL-----GCQEICPACQHAARCDPETG 800
Query: 271 AALQADGRSCTASATQSCNDLCEHFCVPNPDQPGSYSCMCETGYRLAADQHRCEDVDDCI 330
A L G C D+C G Y C+T A D H C
Sbjct: 801 ACLCLPG-----FVGSRCQDVC---------PAGWYGPSCQTRCSCANDGHCHPATGHCS 846
Query: 331 LEPS----PCPQRCVNTQGG----FECHC---YPNYDLVDGECV------------EPVD 367
P C + C G C+C + + D + G C+ +
Sbjct: 847 CAPGWTGFSCQRACDTGHWGPDCSHPCNCSAGHGSCDAISGLCLCEAGYVGPRCEQQCPQ 906
Query: 368 PCFRANCEYQCQ-----PLNQTSYLCVCAEGF--------APIPHEPHRCQMFCNQTACP 414
F CE +CQ + S C C G+ P C+ CN TA
Sbjct: 907 GHFGPGCEQRCQCQHGAACDHVSGACTCPAGWRGTFCEHACPAGFFGLDCRSACNCTA-G 965
Query: 415 ADCDPNTQASCECPEGY----------ILDDGFICTDIDECENGGFCS---GVCHNLPG 460
A CD SC CP G G C+ C NG C G CH PG
Sbjct: 966 AACDA-VNGSCLCPAGRRGPRCAETCPAHTYGHNCSQACACFNGASCDPVHGQCHCAPG 1023
Score = 53.1 bits (126), Expect = 7e-07
Identities = 83/340 (24%), Positives = 111/340 (32%), Gaps = 70/340 (20%)
Query: 182 PGAAAAAVSITYGTPFAARGADFQAL---PVGSSAAVAPLGLQLMCT-APPGAVQGHWAR 237
P A + TYG + A F PV AP + C A P + G R
Sbjct: 984 PRCAETCPAHTYGHNCSQACACFNGASCDPVHGQCHCAPGWMGPSCLQACPAGLYGDNCR 1043
Query: 238 EAPGAWDCSVENGGCEHACNAIPGAPRCQCPAGAALQADGRSC-----TASATQSCNDLC 292
+ C +NGG C+ + G C CP G A A + C A S L
Sbjct: 1044 HS-----CLCQNGG---TCDPVSG--HCACPEGWAGLACEKECLPRDVRAGCRHSGGCLN 1093
Query: 293 EHFCVPNPDQPGSYSCMCETGYRLAADQHRCED--VDDCILEPSPCP--QRCVNTQGGFE 348
C P+ + C+C G+ Q C + + CP C + G
Sbjct: 1094 GGLCDPHTGR-----CLCPAGWTGDKCQSPCLRGWFGEACAQRCSCPPGAACHHVTGA-- 1146
Query: 349 CHCYPNYDLVDGECVEPVDP-CFRANCEYQCQ------PLNQTSYLCVCAEGF------- 394
C C P + C + P F +C CQ + + C CA G+
Sbjct: 1147 CRCPPGF--TGSGCEQACPPGSFGEDCAQMCQCPGENPACHPATGTCSCAAGYHGPSCQQ 1204
Query: 395 -APIPHEPHRCQMFCNQTACPADCDPNTQASCECPEGYILDD----------GFICTDID 443
P C+ C CD T A C CP G++ D G CT +
Sbjct: 1205 RCPPGRYGPGCEQLCG-CLNGGSCDAATGA-CRCPTGFLGTDCNLTCPQGRFGPNCTHVC 1262
Query: 444 ECENGGFCSGVCHNLPGTFECICGPDSALARHIGTDCDSG 483
C G C P T C+C P A G C+ G
Sbjct: 1263 GCGQGAACD------PVTGTCLCPPGRA-----GVRCERG 1291
Score = 52.4 bits (124), Expect = 1e-06
Identities = 67/278 (24%), Positives = 93/278 (33%), Gaps = 60/278 (21%)
Query: 221 QLMCTAPPGAVQ----GHWAREAPGAW-----DCSVENGGCEHACNAIPGAPRCQCPAGA 271
Q +CT PG + + A G +C+ GGCEH C + G+ +C C AG
Sbjct: 383 QQVCTNNPGGYECGCYAGYRLSADGCGCEDVDECASSRGGCEHHCTNLAGSFQCSCEAGY 442
Query: 272 ALQADGRSCTASATQSCNDL---------CEHFCVPNPDQPGSYSCMCETGYRLAADQHR 322
L D R C + + DL H V + P + + AD+
Sbjct: 443 RLHEDRRGC-SPLEEPMVDLDGELPFVRPLPHIAVLQDELPQLFQ-----DDDVGADEEE 496
Query: 323 CEDVDDCILEPSPCPQRCVNTQGGFECHCYPNYDLVDGECVEPVDPCFRAN------CEY 376
E + L C++ G +C + G C+ +D C C
Sbjct: 497 AELRGEHTLTEKFV---CLDDSFGHDCSLTCDDCRNGGTCLLGLDGCDCPEGWTGLICNE 553
Query: 377 QCQP---LNQTSYLCVCAEGFAPIPHEPHRCQMFCNQTACPADCDPNTQ-ASCE--CPEG 430
C P S+ C C G C+ C P +CE CP+G
Sbjct: 554 TCPPDTFGKNCSFSCSCQNGGT------------CDSVTGACRCPPGVSGTNCEDGCPKG 601
Query: 431 YILDDGFICTDIDECENGGFCSGVCHNLPGTFECICGP 468
Y G C C N G CH L G C+C P
Sbjct: 602 YY---GKHCRKKCNCAN----RGRCHRLYGA--CLCDP 630
Score = 49.3 bits (116), Expect = 1e-05
Identities = 69/293 (23%), Positives = 91/293 (31%), Gaps = 74/293 (25%)
Query: 242 AWDCSVENGGCEHACNAIPGAPRCQ-----------CPAGAALQADGRSCTASATQSCND 290
++ CS +NGG C+++ GA RC CP G + + C + C+
Sbjct: 565 SFSCSCQNGG---TCDSVTGACRCPPGVSGTNCEDGCPKGYYGKHCRKKCNCANRGRCHR 621
Query: 291 L--------------CEHFCVPNPDQPGSY------------------SCMCETGYRLAA 318
L C C P PG SC C+ G+R
Sbjct: 622 LYGACLCDPGLYGRFCHLTCPPWAFGPGCSEECQCVQPHTQSCDKRDGSCSCKAGFRGER 681
Query: 319 DQHRCE--DVDDCILEPSPCPQ--RCVNTQGGFECHCYPNYDLVDGECVEPVDPCFRANC 374
Q CE + CP C + G C + D PV F NC
Sbjct: 682 CQAECELGYFGPGCWQACTCPVGVACDSVSGECGKRCPAGFQGEDCGQECPVGT-FGVNC 740
Query: 375 EYQCQ----PLNQTSYLCVC--------AEGFAPIPHEPHRCQMFCNQTACPADCDPNTQ 422
C P + + C C E P CQ C A CDP T
Sbjct: 741 SSSCSCGGAPCHGVTGQCRCPPGRTGEDCEADCPEGRWGLGCQEICPACQHAARCDPETG 800
Query: 423 ASCECPEGYILDDGFICTDI-------DECENGGFCSGVCHNLPGTFECICGP 468
A C C G++ G C D+ C+ C+ H P T C C P
Sbjct: 801 A-CLCLPGFV---GSRCQDVCPAGWYGPSCQTRCSCANDGHCHPATGHCSCAP 849
Score = 46.2 bits (108), Expect = 8e-05
Identities = 29/84 (34%), Positives = 37/84 (44%), Gaps = 9/84 (10%)
Query: 390 CAEGFAPIPHEPHRCQMFCNQTAC--PADCDPNTQASCECPEGYILDDGFICT-DIDECE 446
C G+ P E C+ + C C P + C CP G+ G C D+DEC
Sbjct: 110 CCRGWMQQPDEEGCLSAECSASLCFHGGRCVPGSAQPCHCPPGF---QGPRCQYDVDECR 166
Query: 447 --NGGFCSGVCHNLPGTFECICGP 468
NGG C C N PG++ C C P
Sbjct: 167 THNGG-CQHRCVNTPGSYLCECKP 189
Score = 45.4 bits (106), Expect = 1e-04
Identities = 64/281 (22%), Positives = 86/281 (30%), Gaps = 60/281 (21%)
Query: 244 DCSVENGGCEHACNAIPGAPRCQCPAG---------AALQADGRSCTASATQSCNDLCEH 294
DCS+ C + + G C CP G G++C+ S + C+
Sbjct: 519 DCSLTCDDCRNGGTCLLGLDGCDCPEGWTGLICNETCPPDTFGKNCSFSCSCQNGGTCDS 578
Query: 295 FCVPNPDQPGSYSCMCETGYRLAADQHRCEDVDDCILEPSPCPQRCVNTQGGFECHCYPN 354
PG CE G C +C RC G C C P
Sbjct: 579 VTGACRCPPGVSGTNCEDGCPKGYYGKHCRKKCNCANR-----GRCHRLYGA--CLCDPG 631
Query: 355 YDLVDGECVEPVDP-CFRANCEYQCQPLNQTSYLCVCAEGFAPIPHEPHRCQMFCNQTAC 413
L C P F C +CQ + + C +G C+ C
Sbjct: 632 --LYGRFCHLTCPPWAFGPGCSEECQCVQPHTQSCDKRDGSC-------SCKAGFRGERC 682
Query: 414 PADCD-----PNTQASCECPEGYILDD-----------GFICTDI-DECENGGF------ 450
A+C+ P +C CP G D GF D EC G F
Sbjct: 683 QAECELGYFGPGCWQACTCPVGVACDSVSGECGKRCPAGFQGEDCGQECPVGTFGVNCSS 742
Query: 451 ---CSGV-CHNLPGTFECICGPDSALARHIGTDCDSGKVDG 487
C G CH + G +C C P G DC++ +G
Sbjct: 743 SCSCGGAPCHGVTG--QCRCPPG-----RTGEDCEADCPEG 776
Score = 44.7 bits (104), Expect = 2e-04
Identities = 68/271 (25%), Positives = 83/271 (30%), Gaps = 84/271 (30%)
Query: 210 GSSAAVAPLGLQLMCTAPPGAVQGHWAREAPG-------AWDCSVENGGCEHACNAIPGA 262
G AA P+ +C PPG R P CS NGG HA N G+
Sbjct: 1265 GQGAACDPVTGTCLC--PPGRAGVRCERGCPQNRFGVGCEHTCSCRNGGLCHASN---GS 1319
Query: 263 PRC-----------QCPAGAALQADGRSCTASATQSC--------------NDLCEHFCV 297
C CP G A C+ +C CEH C
Sbjct: 1320 CSCGLGWTGRHCELACPPGRYGAACHLECSCHNNSTCEPATGTCRCGPGFYGQACEHPCP 1379
Query: 298 PN----------------PDQPGSYSCMCETGYRLAADQHRCEDVDDCILEPSPCPQRCV 341
P P P S C+C G+ H CE + C QRC
Sbjct: 1380 PGFHGAGCQGLCWCQHGAPCDPISGRCLCPAGFH----GHFCERGCEPGSFGEGCHQRC- 1434
Query: 342 NTQGGFECHCYPNYDLVDGECVEPVDPCFRANCEYQCQPLNQTSYLCVCAEGFAPIPHEP 401
+ GG C D V G C+ P A C C+ F P
Sbjct: 1435 DCDGGAPC------DPVTGLCLCPPGRS-GATCNLDCR-----------RGQFGP----- 1471
Query: 402 HRCQMFCNQTACPADCDPNTQASCECPEGYI 432
C + C+ ADCDP C C +GY+
Sbjct: 1472 -SCTLHCD-CGGGADCDP-VSGQCHCVDGYM 1499
Score = 42.4 bits (98), Expect = 0.001
Identities = 70/274 (25%), Positives = 89/274 (32%), Gaps = 60/274 (21%)
Query: 249 NGGCEHACNAIPGAPRCQCPAGAALQADGRSCTASATQS-CNDLCEHFCVPNPDQPGSY- 306
+GGC + P RC CPAG G C + + + C C P +
Sbjct: 1088 SGGCLNGGLCDPHTGRCLCPAGWT----GDKCQSPCLRGWFGEACAQRCSCPPGAACHHV 1143
Query: 307 --SCMCETGYRLAADQHRCED---VDDCILEPSPCP---QRCVNTQGGFECHCYPNYDLV 358
+C C G+ + + C +DC + CP C G C C Y
Sbjct: 1144 TGACRCPPGFTGSGCEQACPPGSFGEDC-AQMCQCPGENPACHPATG--TCSCAAGYH-- 1198
Query: 359 DGECVEPVDP-CFRANCEYQCQPLNQTSY-----LCVCAEGFAPI------------PHE 400
C + P + CE C LN S C C GF P+
Sbjct: 1199 GPSCQQRCPPGRYGPGCEQLCGCLNGGSCDAATGACRCPTGFLGTDCNLTCPQGRFGPNC 1258
Query: 401 PHRCQMFCNQTACPADCDPNTQASCECPEGYI----------LDDGFICTDIDECENGGF 450
H C C Q A CDP T +C CP G G C C NG
Sbjct: 1259 THVCG--CGQGAA---CDPVT-GTCLCPPGRAGVRCERGCPQNRFGVGCEHTCSCRNG-- 1310
Query: 451 CSGVCHNLPGTFECICGPDSALARHIGTDCDSGK 484
G+CH G+ C CG RH C G+
Sbjct: 1311 --GLCHASNGS--CSCGL-GWTGRHCELACPPGR 1339
>gi|66346695 fibrillin 2 precursor [Homo sapiens]
Length = 2912
Score = 130 bits (327), Expect = 3e-30
Identities = 85/237 (35%), Positives = 114/237 (48%), Gaps = 19/237 (8%)
Query: 244 DCSVENGGCEHACNAIPGAPRCQCPAGAALQADGRSCT-ASATQSCNDLCEHFCVPNPDQ 302
+C + NGGC+ C G+ C C G AL DGRSC ++ D+C+ N
Sbjct: 1245 ECMIMNGGCDTQCTNSEGSYECSCSEGYALMPDGRSCADIDECENNPDICDGGQCTN--I 1302
Query: 303 PGSYSCMCETGYRLAADQHRCEDVDDCILEPSPCP-QRCVNTQGGFECHCYPNYDLVDGE 361
PG Y C+C G+ + D C DV++C L + C C NT+G F CHC Y + G
Sbjct: 1303 PGEYRCLCYDGFMASMDMKTCIDVNECDLNSNICMFGECENTKGSFICHCQLGYSVKKGT 1362
Query: 362 --CVEPVDPC--FRANCEYQCQPLN-QTSYLCVCAEGFAPIP---HEPHRCQMFCNQTAC 413
C + VD C NC+ LN S+ C C EG+ + C +Q +
Sbjct: 1363 TGCTD-VDECEIGAHNCDMHASCLNIPGSFKCSCREGWIGNGIKCIDLDECSNGTHQCSI 1421
Query: 414 PADCDPNTQAS--CECPEGYILDDGFICTDIDEC-ENGGFC-SGVCHNLPGTFECIC 466
A C NT S C C EG+ DGF C+D+DEC EN C +G C N+PG + C C
Sbjct: 1422 NAQC-VNTPGSYRCACSEGF-TGDGFTCSDVDECAENINLCENGQCLNVPGAYRCEC 1476
Score = 122 bits (307), Expect = 7e-28
Identities = 81/245 (33%), Positives = 110/245 (44%), Gaps = 22/245 (8%)
Query: 244 DCSVENGGCEHACNAI--PGAPRCQCPAGAALQADGRSCTASATQSCNDLCEH-FCVPNP 300
+CS + C+ + I PG+ RC+C AG L +G + ++C H CV
Sbjct: 1853 ECSNGDNLCQRNADCINSPGSYRCECAAGFKLSPNGACVDRNECLEIPNVCSHGLCV--- 1909
Query: 301 DQPGSYSCMCETGYRLAADQHRCEDVDDCILEPSPCPQ-RCVNTQGGFECHCYPNYDLVD 359
D GSY C+C G++ + DQ C DVD+C E PC C NT G + C CYP ++L
Sbjct: 1910 DLQGSYQCICHNGFKASQDQTMCMDVDEC--ERHPCGNGTCKNTVGSYNCLCYPGFELTH 1967
Query: 360 GECVEPVDPC---FRANCEYQCQPLNQTSYLCVCAEGFAPIPHEPHRCQMFCNQTACPAD 416
+D C F C S+ C+C EG+ P + C A P
Sbjct: 1968 NNDCLDIDECSSFFGQVCRNGRCFNEIGSFKCLCNEGYELTP-DGKNCIDTNECVALPGS 2026
Query: 417 CDPNT------QASCECPEGYILDDGFICTDIDEC-ENGGFC-SGVCHNLPGTFECICGP 468
C P T C CP GY + C DI+EC E+ C G C N PG F+C+C P
Sbjct: 2027 CSPGTCQNLEGSFRCICPPGYEVKSE-NCIDINECDEDPNICLFGSCTNTPGGFQCLCPP 2085
Query: 469 DSALA 473
L+
Sbjct: 2086 GFVLS 2090
Score = 108 bits (270), Expect = 1e-23
Identities = 72/228 (31%), Positives = 103/228 (45%), Gaps = 23/228 (10%)
Query: 256 CNAIPGAPRCQCPAGAALQADGRSCTASATQSCND-LCEHF-CVPNPDQPGSYSCMCETG 313
C G+ +C CP G L C S +D LC + CV + G+Y C C G
Sbjct: 1174 CVNTEGSFQCDCPLGHELSPSREDCVDINECSLSDNLCRNGKCV---NMIGTYQCSCNPG 1230
Query: 314 YRLAADQHRCEDVDDCILEPSPCPQRCVNTQGGFECHCYPNYDLV-DGECVEPVDPCFRA 372
Y+ D+ C D+D+C++ C +C N++G +EC C Y L+ DG +D C
Sbjct: 1231 YQATPDRQGCTDIDECMIMNGGCDTQCTNSEGSYECSCSEGYALMPDGRSCADIDECENN 1290
Query: 373 N--CE-YQCQPLNQTSYLCVCAEGFAPIPH-----EPHRCQMFCNQTACPADCDPNTQAS 424
C+ QC + Y C+C +GF + + C + N C NT+ S
Sbjct: 1291 PDICDGGQCTNI-PGEYRCLCYDGFMASMDMKTCIDVNECDL--NSNICMFGECENTKGS 1347
Query: 425 --CECPEGYILDDGFI-CTDIDECENGGF---CSGVCHNLPGTFECIC 466
C C GY + G CTD+DECE G C N+PG+F+C C
Sbjct: 1348 FICHCQLGYSVKKGTTGCTDVDECEIGAHNCDMHASCLNIPGSFKCSC 1395
Score = 97.8 bits (242), Expect = 2e-20
Identities = 77/271 (28%), Positives = 105/271 (38%), Gaps = 49/271 (18%)
Query: 244 DCSVENGGCEHA-CNAIPGAPRCQCPAGAALQADGRSCT-----ASATQSCNDLCEHFCV 297
+C V C + C G+ RC C G G SC + + + CN +C++
Sbjct: 2452 ECKVMPNLCTNGQCINTMGSFRCFCKVGYTTDISGTSCIDLDECSQSPKPCNYICKN--- 2508
Query: 298 PNPDQPGSYSCMCETGYRLAADQHRCEDVDDCILEPSPCPQRCVNTQGGFECHCYPNYD- 356
GSY C C GY L D C+D+D+C + C CVNT GGF C C P +
Sbjct: 2509 ----TEGSYQCSCPRGYVLQEDGKTCKDLDECQTKQHNCQFLCVNTLGGFTCKCPPGFTQ 2564
Query: 357 -----LVDGECVEPVDPCFRANCEYQCQPLNQTSYLCVCAEGFA-----------PIPHE 400
+ + EC C + CQ S+ C C GF+
Sbjct: 2565 HHTACIDNNECGSQPSLC---GAKGICQN-TPGSFSCECQRGFSLDATGLNCEDVDECDG 2620
Query: 401 PHRCQMFCNQTACPADCDPNTQASCECPEGYILDDGF-ICTDIDECENGGFC-SGVCHNL 458
HRCQ C C CP+GYI + C D +EC N C S C+N
Sbjct: 2621 NHRCQHGCQNIL--------GGYRCGCPQGYIQHYQWNQCVDENECSNPNACGSASCYNT 2672
Query: 459 PGTFECICGPDSAL-----ARHIGTDCDSGK 484
G+++C C + A H +C S K
Sbjct: 2673 LGSYKCACPSGFSFDQFSSACHDVNECSSSK 2703
Score = 97.1 bits (240), Expect = 4e-20
Identities = 81/265 (30%), Positives = 103/265 (38%), Gaps = 35/265 (13%)
Query: 224 CTAPPGAVQGHWAREAPGAWDCSVENGGCEHACNAIPGAPRCQCPAGAALQADGRSCT-- 281
C G +R +CS +N CN +PG C C G L G +CT
Sbjct: 1474 CECEMGFTPASDSRSCQDIDECSFQNICVFGTCNNLPGMFHCICDDGYELDRTGGNCTDI 1533
Query: 282 ---ASATQSCNDLCEHFCVPNPDQPGSYSCMCETGYRLAADQHRCED--VDDCILEPSPC 336
A N LC + PG Y C C ++L C D V +C L+ P
Sbjct: 1534 DECADPINCVNGLC-------VNTPGRYECNCPPDFQLNPTGVGCVDNRVGNCYLKFGP- 1585
Query: 337 PQRCVNTQGGFECHCYPNYDLVDGECVEPVDPCFRANCEYQCQPLNQTSY--LCVCAEGF 394
G C+ + C + + CE C P+N T Y LC EGF
Sbjct: 1586 -----RGDGSLSCNTEIGVGVSRSSCCCSLGKAWGNPCE-TCPPVNSTEYYTLCPGGEGF 1639
Query: 395 APIP-----HEPHRCQMFCNQTACPADCDPNTQAS--CECPEGYIL-DDGFICTDIDEC- 445
P P + CQ C NT S CECP+GY L +D IC DIDEC
Sbjct: 1640 RPNPITIILEDIDECQEL--PGLCQGGNCINTFGSFQCECPQGYYLSEDTRICEDIDECF 1697
Query: 446 ENGGFCS-GVCHNLPGTFECICGPD 469
+ G C G C+N G + CIC P+
Sbjct: 1698 AHPGVCGPGTCYNTLGNYTCICPPE 1722
Score = 95.1 bits (235), Expect = 2e-19
Identities = 72/262 (27%), Positives = 104/262 (39%), Gaps = 65/262 (24%)
Query: 267 CPAGAALQADGRSCTASATQSCNDLCEHF---CVPNP--DQPGSYSCMCETGYRLAADQH 321
CP GA G T + C+ F C + GS+ C C +G+ L ++
Sbjct: 1052 CPRGAGFANRGDVLTGRPFYKDINECKAFPGMCTYGKCRNTIGSFKCRCNSGFALDMEER 1111
Query: 322 RCEDVDDCILEPSPCPQR-CVNTQGGFECHCYPNYD---LVDGECVEPVDPC-------- 369
C D+D+C + P C CVNT G FEC C+ Y+ ++ C++ +D C
Sbjct: 1112 NCTDIDECRISPDLCGSGICVNTPGSFECECFEGYESGFMMMKNCMD-IDECERNPLLCR 1170
Query: 370 ----------FRANC---------EYQCQPLNQTS-----------------YLCVCAEG 393
F+ +C C +N+ S Y C C G
Sbjct: 1171 GGTCVNTEGSFQCDCPLGHELSPSREDCVDINECSLSDNLCRNGKCVNMIGTYQCSCNPG 1230
Query: 394 FAPIPHEPHRC----QMFCNQTACPADCDPNTQAS--CECPEGY-ILDDGFICTDIDECE 446
+ P + C + C C N++ S C C EGY ++ DG C DIDECE
Sbjct: 1231 YQATP-DRQGCTDIDECMIMNGGCDTQC-TNSEGSYECSCSEGYALMPDGRSCADIDECE 1288
Query: 447 NG-GFC-SGVCHNLPGTFECIC 466
N C G C N+PG + C+C
Sbjct: 1289 NNPDICDGGQCTNIPGEYRCLC 1310
Score = 94.4 bits (233), Expect = 3e-19
Identities = 82/286 (28%), Positives = 111/286 (38%), Gaps = 64/286 (22%)
Query: 256 CNAIPGAPRCQCPAGAALQADGRSCTASATQSCNDLCEHFCVPNP--DQPGSYSCMCETG 313
C IPG RC C G D ++C C DL + C+ + GS+ C C+ G
Sbjct: 1299 CTNIPGEYRCLCYDGFMASMDMKTCID--VNEC-DLNSNICMFGECENTKGSFICHCQLG 1355
Query: 314 YRLAADQHRCEDVDDCILEPSPCPQR--CVNTQGGFECHCYPNYDLVDGECVEPVDPCFR 371
Y + C DVD+C + C C+N G F+C C + +C++ +D C
Sbjct: 1356 YSVKKGTTGCTDVDECEIGAHNCDMHASCLNIPGSFKCSCREGWIGNGIKCID-LDECSN 1414
Query: 372 AN--CEYQCQPLNQT-SYLCVCAEGFAP-------------------------IPHEPHR 403
C Q +N SY C C+EGF +P +R
Sbjct: 1415 GTHQCSINAQCVNTPGSYRCACSEGFTGDGFTCSDVDECAENINLCENGQCLNVPGA-YR 1473
Query: 404 CQMFCNQTACPAD----CDPNTQAS------------------CECPEGYILD-DGFICT 440
C+ C PA C + S C C +GY LD G CT
Sbjct: 1474 CE--CEMGFTPASDSRSCQDIDECSFQNICVFGTCNNLPGMFHCICDDGYELDRTGGNCT 1531
Query: 441 DIDECENGGFC-SGVCHNLPGTFECICGPDSALARHIGTDCDSGKV 485
DIDEC + C +G+C N PG +EC C PD L G C +V
Sbjct: 1532 DIDECADPINCVNGLCVNTPGRYECNCPPDFQL-NPTGVGCVDNRV 1576
Score = 93.2 bits (230), Expect = 6e-19
Identities = 82/269 (30%), Positives = 106/269 (39%), Gaps = 63/269 (23%)
Query: 255 ACNAIPGAPRCQCPAGAALQADGRSC------------------------TASATQSCN- 289
+C PG +C CP G L +GR C T A C+
Sbjct: 2071 SCTNTPGGFQCLCPPGFVLSDNGRRCFDTRQSFCFTNFENGKCSVPKAFNTTKAKCCCSK 2130
Query: 290 -------DLCEHFCVPNPDQPGSYSCMCETGYRLAADQHRC-EDVDDCILEPSPCPQ-RC 340
D CE P D+ ++ +C G+ H EDV++C+ P C +C
Sbjct: 2131 MPGEGWGDPCE--LCPKDDEV-AFQDLCPYGHGTVPSLHDTREDVNECLESPGICSNGQC 2187
Query: 341 VNTQGGFECHCYPNYDL-------VDGECVEPVDPCFRANCEYQCQPLNQTSYLCVCAEG 393
+NT G F C C Y+L VD + +PC C S+ C C EG
Sbjct: 2188 INTDGSFRCECPMGYNLDYTGVRCVDTDECSIGNPCGNGTCTNVIG-----SFECNCNEG 2242
Query: 394 FAPIP----HEPHRCQMFCNQTACPADCDPNTQAS--CECPEGYIL-DDGFICTDIDECE 446
F P P + + C N C C NT S C CP GY L +D +C D+DEC
Sbjct: 2243 FEPGPMMNCEDINECAQ--NPLLCAFRC-MNTFGSYECTCPIGYALREDQKMCKDLDECA 2299
Query: 447 NGGF-CSG---VCHNLPGTFECICGPDSA 471
G C +C NL GTF CIC P A
Sbjct: 2300 EGLHDCESRGMMCKNLIGTFMCICPPGMA 2328
Score = 92.4 bits (228), Expect = 1e-18
Identities = 81/303 (26%), Positives = 117/303 (38%), Gaps = 51/303 (16%)
Query: 207 LPVGSSAAVAPLGLQLMCTAPPGAVQGHWAREAPGAWD-----CSVENGGCEHACNAIPG 261
L VG V + + T G +G R PGA C+ + G C P
Sbjct: 688 LAVGMDGRVC-VDTHMRSTCYGGIKKGVCVRPFPGAVTKSECCCANPDYGFGEPCQPCPA 746
Query: 262 APRCQ----CPAGAALQADGRS---CTASATQSCNDLCEHFCVPNPDQPGSYSCMCETGY 314
+ C +G + DGR C N +CE+ GSY C C +GY
Sbjct: 747 KNSAEFHGLCSSGVGITVDGRDINECALDPDICANGICENL-------RGSYRCNCNSGY 799
Query: 315 RLAADQHRCEDVDDCILEPSPCPQR-CVNTQGGFECHCYPNYDL-VDGECVEPVD----- 367
A C D+D+C++ C C NT G + C C P Y + E E ++
Sbjct: 800 EPDASGRNCIDIDECLVNRLLCDNGLCRNTPGSYSCTCPPGYVFRTETETCEDINECESN 859
Query: 368 PCFRANCEY-------QCQP---LNQTSYLCVCA-EGFAPIPHEPHRCQMFCNQTACPAD 416
PC C +C P L+ T +C+ + +G + + RC++ N ++
Sbjct: 860 PCVNGACRNNLGSFNCECSPGSKLSSTGLICIDSLKGTCWLNIQDSRCEVNINGATLKSE 919
Query: 417 CDPNTQAS-------CE----CPEGYILDDGFICTDIDECE-NGGFC-SGVCHNLPGTFE 463
C A+ CE CP G G C D++ECE G C +G C N G+F
Sbjct: 920 CCATLGAAWGSPCERCELDTACPRGLARIKGVTCEDVNECEVFPGVCPNGRCVNSKGSFH 979
Query: 464 CIC 466
C C
Sbjct: 980 CEC 982
Score = 91.7 bits (226), Expect = 2e-18
Identities = 77/258 (29%), Positives = 106/258 (41%), Gaps = 65/258 (25%)
Query: 261 GAPRCQCPAGAALQADGRSCTASATQSCNDLCEHFCVPNPDQ--PGSYSCMCETGYRLAA 318
G+ +C C G L DG++C T C L C P Q GS+ C+C GY + +
Sbjct: 1995 GSFKCLCNEGYELTPDGKNCID--TNECVAL-PGSCSPGTCQNLEGSFRCICPPGYEVKS 2051
Query: 319 DQHRCEDVDDCILEPSPCP-QRCVNTQGGFECHCYPNYDLVD------------------ 359
+ C D+++C +P+ C C NT GGF+C C P + L D
Sbjct: 2052 EN--CIDINECDEDPNICLFGSCTNTPGGFQCLCPPGFVLSDNGRRCFDTRQSFCFTNFE 2109
Query: 360 -GECVEPV--------------------DPCFRANCEYQCQPLNQTSYLCVCAEGFAPIP 398
G+C P DPC C ++ ++ +C G +P
Sbjct: 2110 NGKCSVPKAFNTTKAKCCCSKMPGEGWGDPC------ELCPKDDEVAFQDLCPYGHGTVP 2163
Query: 399 --HEPHRCQMFCNQTACPADCDP----NTQAS--CECPEGYILD-DGFICTDIDECENGG 449
H+ C ++ P C NT S CECP GY LD G C D DEC G
Sbjct: 2164 SLHDTREDVNECLES--PGICSNGQCINTDGSFRCECPMGYNLDYTGVRCVDTDECSIGN 2221
Query: 450 FC-SGVCHNLPGTFECIC 466
C +G C N+ G+FEC C
Sbjct: 2222 PCGNGTCTNVIGSFECNC 2239
Score = 87.8 bits (216), Expect = 2e-17
Identities = 71/250 (28%), Positives = 98/250 (39%), Gaps = 54/250 (21%)
Query: 267 CPAGAALQADGRSCTASATQSCNDL---CEHFCVPNPDQPGSYSCMCETGYRLAADQHRC 323
CP G + + + C +L C+ N GS+ C C GY L+ D C
Sbjct: 1633 CPGGEGFRPNPITIILEDIDECQELPGLCQGGNCINTF--GSFQCECPQGYYLSEDTRIC 1690
Query: 324 EDVDDCILEPSPC-PQRCVNTQGGFECHCYPNYDLVDG--ECVEPVDP-CFRANCEYQCQ 379
ED+D+C P C P C NT G + C C P Y V+G C++ C+R+ C+
Sbjct: 1691 EDIDECFAHPGVCGPGTCYNTLGNYTCICPPEYMQVNGGHNCMDMRKSFCYRSYNGTTCE 1750
Query: 380 ---PLNQTSYLCVCAEGFAPIPHEPHRCQ--------------------MFCNQTACPAD 416
P N T +C C ++P C+ F T D
Sbjct: 1751 NELPFNVTKRMCCCTYNVGKAWNKP--CEPCPTPGTADFKTICGNIPGFTFDIHTGKAVD 1808
Query: 417 CD-----PNTQAS-----------CECPEGYILDD-GFICTDIDECENG-GFC--SGVCH 456
D P A+ CECP G+ +D +C DIDEC NG C + C
Sbjct: 1809 IDECKEIPGICANGVCINQIGSFRCECPTGFSYNDLLLVCEDIDECSNGDNLCQRNADCI 1868
Query: 457 NLPGTFECIC 466
N PG++ C C
Sbjct: 1869 NSPGSYRCEC 1878
Score = 86.3 bits (212), Expect = 7e-17
Identities = 65/228 (28%), Positives = 98/228 (42%), Gaps = 35/228 (15%)
Query: 270 GAALQADGRSCTASATQSCN---DLCEHF--------CVPNPDQPGSYSCMCETGYRLAA 318
GA + A G+ + N D+C+H C+P SY C C GY+ A
Sbjct: 473 GAGVGAGGQGPIITGLTILNQTIDICKHHANLCLNGRCIPTVS---SYRCECNMGYKQDA 529
Query: 319 DQHRCEDVDDCILEPSPCPQ-RCVNTQGGFECHCYPNYDLVDGE--CVEPVDPCFRAN-- 373
+ C DVD+C +PC CVNT G + C C+ + + C++ +D C +
Sbjct: 530 NGD-CIDVDEC--TSNPCTNGDCVNTPGSYYCKCHAGFQRTPTKQACID-IDECIQNGVL 585
Query: 374 CEYQCQPLNQTSYLCVCAEGFA-------PIPHEPHRCQMFCNQTACPADCDPNTQASCE 426
C+ S+ C+C GF + H+ C C + + C
Sbjct: 586 CKNGRCVNTDGSFQCICNAGFELTTDGKNCVDHDECTTTNMCLNGMC---INEDGSFKCI 642
Query: 427 CPEGYIL-DDGFICTDIDECENGGFC-SGVCHNLPGTFECICGPDSAL 472
C G++L +G CTD+DEC+ G C +G C N G+F C C P A+
Sbjct: 643 CKPGFVLAPNGRYCTDVDECQTPGICMNGHCINSEGSFRCDCPPGLAV 690
Score = 81.6 bits (200), Expect = 2e-15
Identities = 67/241 (27%), Positives = 95/241 (39%), Gaps = 40/241 (16%)
Query: 244 DCSVENGGCEHA-CNAIPGAPRCQCPAGAALQADGRSCTASATQSCNDLCEHFCVPNPDQ 302
+C G C + C G+ RC+CP G L G C + S + C + N
Sbjct: 2174 ECLESPGICSNGQCINTDGSFRCECPMGYNLDYTGVRCVDTDECSIGNPCGNGTCTNVI- 2232
Query: 303 PGSYSCMCETGYRLAADQHRCEDVDDCILEPSPCPQRCVNTQGGFECHCYPNYDLVDGEC 362
GS+ C C G+ CED+++C P C RC+NT G +EC C Y L +
Sbjct: 2233 -GSFECNCNEGFE-PGPMMNCEDINECAQNPLLCAFRCMNTFGSYECTCPIGYALRED-- 2288
Query: 363 VEPVDPCFRANCEYQCQPLNQTSYLCVCAEGFAPIPHEPHRCQMFCNQTACPADCDPNTQ 422
+ C+ L++ CAEG H+ M C
Sbjct: 2289 ------------QKMCKDLDE------CAEGL----HDCESRGMMCKNLI--------GT 2318
Query: 423 ASCECPEGYI-LDDGFICTDIDECE-NGGFC-SGVCHNLPGTFECICGPDSALARHIGTD 479
C CP G DG C D +EC G C +G C N+ G++ C C + + GT+
Sbjct: 2319 FMCICPPGMARRPDGEGCVDENECRTKPGICENGRCVNIIGSYRCECN-EGFQSSSSGTE 2377
Query: 480 C 480
C
Sbjct: 2378 C 2378
Score = 80.5 bits (197), Expect = 4e-15
Identities = 84/276 (30%), Positives = 109/276 (39%), Gaps = 63/276 (22%)
Query: 241 GAWDCSVENGGCEHACNAIPGAPRCQCPAGAALQADGRSCTASATQSCND---LCEHFCV 297
G CS+ N C + PG+ RC C G DG +C S C + LCE+
Sbjct: 1415 GTHQCSI-NAQCVNT----PGSYRCACSEG--FTGDGFTC--SDVDECAENINLCENGQC 1465
Query: 298 PNPDQPGSYSCMCETGYRLAADQHRCEDVDDCILEPSPCPQRCVNTQGGFECHCYPNYDL 357
N PG+Y C CE G+ A+D C+D+D+C + C N G F C C Y+L
Sbjct: 1466 LNV--PGAYRCECEMGFTPASDSRSCQDIDECSFQNICVFGTCNNLPGMFHCICDDGYEL 1523
Query: 358 ---------VDGECVEPVDPCFRANC-------EYQCQP---LNQTSYLCV------CAE 392
+D EC +P++ C C E C P LN T CV C
Sbjct: 1524 DRTGGNCTDID-ECADPIN-CVNGLCVNTPGRYECNCPPDFQLNPTGVGCVDNRVGNCYL 1581
Query: 393 GFAPIPHEPHRCQ----MFCNQTACPADCDPNTQASCE-CP-----EGYILDDG------ 436
F P C + ++++C CE CP E Y L G
Sbjct: 1582 KFGPRGDGSLSCNTEIGVGVSRSSCCCSLGKAWGNPCETCPPVNSTEYYTLCPGGEGFRP 1641
Query: 437 ----FICTDIDEC-ENGGFC-SGVCHNLPGTFECIC 466
I DIDEC E G C G C N G+F+C C
Sbjct: 1642 NPITIILEDIDECQELPGLCQGGNCINTFGSFQCEC 1677
Score = 78.6 bits (192), Expect = 1e-14
Identities = 63/228 (27%), Positives = 87/228 (38%), Gaps = 37/228 (16%)
Query: 224 CTAPPGAVQGHWAREAPGAWDCSVENGGCEHACNAIPGAPRCQCPAGAALQ----ADGRS 279
C+ P G V + +C + C+ C G C+CP G D
Sbjct: 2515 CSCPRGYVLQEDGKTCKDLDECQTKQHNCQFLCVNTLGGFTCKCPPGFTQHHTACIDNNE 2574
Query: 280 CTASATQ-SCNDLCEHFCVPNPDQPGSYSCMCETGYRLAADQHRCEDVDDCILEPSPCPQ 338
C + + +C+ + PGS+SC C+ G+ L A CEDVD+C C
Sbjct: 2575 CGSQPSLCGAKGICQ-------NTPGSFSCECQRGFSLDATGLNCEDVDECD-GNHRCQH 2626
Query: 339 RCVNTQGGFECHCYPNY-------DLVD-GECVEPVDPCFRANCEYQCQPLNQTSYLCVC 390
C N GG+ C C Y VD EC P + C A+C SY C C
Sbjct: 2627 GCQNILGGYRCGCPQGYIQHYQWNQCVDENECSNP-NACGSASCYN-----TLGSYKCAC 2680
Query: 391 AEG-----FAPIPHEPHRCQMFCNQTACPADCDPNTQAS--CECPEGY 431
G F+ H+ + C ++ C C NT+ C CP GY
Sbjct: 2681 PSGFSFDQFSSACHDVNECS--SSKNPCNYGCS-NTEGGYLCGCPPGY 2725
Score = 78.2 bits (191), Expect = 2e-14
Identities = 75/266 (28%), Positives = 96/266 (36%), Gaps = 38/266 (14%)
Query: 224 CTAPPGAVQGHWAREAPGAWDCSVENGGCEHACNAIPGAPRCQCPAGAALQADGRSCTAS 283
C PG V R +C C G+ RC CP G A+ DGR C +
Sbjct: 641 CICKPGFVLAPNGRYCTDVDECQTPGICMNGHCINSEGSFRCDCPPGLAVGMDGRVCVDT 700
Query: 284 ATQSC--NDLCEHFCV-PNPDQPGSYSCMCETGYRLAADQHRCEDVDDCILEP-SPCPQR 339
+S + + CV P P C C + D EP PCP +
Sbjct: 701 HMRSTCYGGIKKGVCVRPFPGAVTKSECCCA-------------NPDYGFGEPCQPCPAK 747
Query: 340 CVNTQGGFECHCYPNYDL-VDG----ECVEPVDPCFRANCEYQCQPLNQTSYLCVCAEGF 394
F C + VDG EC D C CE + SY C C G+
Sbjct: 748 ---NSAEFHGLCSSGVGITVDGRDINECALDPDICANGICENL-----RGSYRCNCNSGY 799
Query: 395 APIPHEPHRC----QMFCNQTACPADCDPNTQAS--CECPEGYIL-DDGFICTDIDECEN 447
P C + N+ C NT S C CP GY+ + C DI+ECE+
Sbjct: 800 EP-DASGRNCIDIDECLVNRLLCDNGLCRNTPGSYSCTCPPGYVFRTETETCEDINECES 858
Query: 448 GGFCSGVCHNLPGTFECICGPDSALA 473
+G C N G+F C C P S L+
Sbjct: 859 NPCVNGACRNNLGSFNCECSPGSKLS 884
Score = 76.3 bits (186), Expect = 7e-14
Identities = 50/181 (27%), Positives = 63/181 (34%), Gaps = 43/181 (23%)
Query: 224 CTAPPGAVQGHWA--------------------REAPGAWDCSVENG------------- 250
C PPG Q H A + PG++ C + G
Sbjct: 2556 CKCPPGFTQHHTACIDNNECGSQPSLCGAKGICQNTPGSFSCECQRGFSLDATGLNCEDV 2615
Query: 251 -------GCEHACNAIPGAPRCQCPAGAALQADGRSCTASATQSCNDLCEHFCVPNPDQP 303
C+H C I G RC CP G C S + C N
Sbjct: 2616 DECDGNHRCQHGCQNILGGYRCGCPQGYIQHYQWNQCVDENECSNPNACGSASCYNT--L 2673
Query: 304 GSYSCMCETGYRLAADQHRCEDVDDCILEPSPCPQRCVNTQGGFECHCYPNYDLV-DGEC 362
GSY C C +G+ C DV++C +PC C NT+GG+ C C P Y V G C
Sbjct: 2674 GSYKCACPSGFSFDQFSSACHDVNECSSSKNPCNYGCSNTEGGYLCGCPPGYYRVGQGHC 2733
Query: 363 V 363
V
Sbjct: 2734 V 2734
Score = 75.1 bits (183), Expect = 2e-13
Identities = 70/276 (25%), Positives = 102/276 (36%), Gaps = 55/276 (19%)
Query: 244 DCSVENGGCEHA-CNAIPGAPRCQCPAGAALQADGRSCTASATQSC-----NDLCEHFCV 297
+C V G C + C G+ C+CP G L GR C + C D C H
Sbjct: 958 ECEVFPGVCPNGRCVNSKGSFHCECPEGLTLDGTGRVCLDIRMEQCYLKWDEDECIH--- 1014
Query: 298 PNPDQPGSYSCMCETGYRLAADQHRC-------------------------------EDV 326
P P + +C C G + C +D+
Sbjct: 1015 PVPGKFRMDACCCAVGAAWGTECEECPKPGTKEYETLCPRGAGFANRGDVLTGRPFYKDI 1074
Query: 327 DDCILEPSPCPQ-RCVNTQGGFECHCYPNY--DLVDGECVEPVDPCFRAN--CEYQCQPL 381
++C P C +C NT G F+C C + D+ + C + +D C + C
Sbjct: 1075 NECKAFPGMCTYGKCRNTIGSFKCRCNSGFALDMEERNCTD-IDECRISPDLCGSGICVN 1133
Query: 382 NQTSYLCVCAEGFAPIPHEPHRC----QMFCNQTACPADCDPNTQAS--CECPEGYILDD 435
S+ C C EG+ C + N C NT+ S C+CP G+ L
Sbjct: 1134 TPGSFECECFEGYESGFMMMKNCMDIDECERNPLLCRGGTCVNTEGSFQCDCPLGHELSP 1193
Query: 436 G-FICTDIDECE-NGGFC-SGVCHNLPGTFECICGP 468
C DI+EC + C +G C N+ GT++C C P
Sbjct: 1194 SREDCVDINECSLSDNLCRNGKCVNMIGTYQCSCNP 1229
Score = 75.1 bits (183), Expect = 2e-13
Identities = 57/213 (26%), Positives = 84/213 (39%), Gaps = 17/213 (7%)
Query: 280 CTASATQSCNDLCEHFCVPNPDQPGSYSCMCET--GYRLAADQHRCEDVDDCILEPSPCP 337
CT + ++ N CE P + +C G+ + D+D+C P C
Sbjct: 1764 CTYNVGKAWNKPCEPCPTPGT---ADFKTICGNIPGFTFDIHTGKAVDIDECKEIPGICA 1820
Query: 338 QR-CVNTQGGFECHCYPNYDLVDGECV-EPVDPCFRAN--CEYQCQPLNQT-SYLCVCAE 392
C+N G F C C + D V E +D C + C+ +N SY C CA
Sbjct: 1821 NGVCINQIGSFRCECPTGFSYNDLLLVCEDIDECSNGDNLCQRNADCINSPGSYRCECAA 1880
Query: 393 GFAPIPH----EPHRCQMFCNQTACPADCDPNTQASCECPEGY-ILDDGFICTDIDECEN 447
GF P+ + + C N + D C C G+ D +C D+DECE
Sbjct: 1881 GFKLSPNGACVDRNECLEIPNVCSHGLCVDLQGSYQCICHNGFKASQDQTMCMDVDECER 1940
Query: 448 GGFCSGVCHNLPGTFECICGPDSALARHIGTDC 480
+G C N G++ C+C P L + DC
Sbjct: 1941 HPCGNGTCKNTVGSYNCLCYPGFELTHN--NDC 1971
Score = 72.0 bits (175), Expect = 1e-12
Identities = 72/289 (24%), Positives = 102/289 (35%), Gaps = 64/289 (22%)
Query: 249 NGGCEHACNAIPGAPRCQCPAGAALQADGRSCTASATQSCND-LCEHFCVPNPDQPGSYS 307
NG C + PG+ C+C AG ++C N LC++ N D GS+
Sbjct: 546 NGDCVNT----PGSYYCKCHAGFQRTPTKQACIDIDECIQNGVLCKNGRCVNTD--GSFQ 599
Query: 308 CMCETGYRLAADQHRCEDVDDCILEPSPCPQRCVNTQGGFECHCYPNYDLV-DGECVEPV 366
C+C G+ L D C D D+C C+N G F+C C P + L +G V
Sbjct: 600 CICNAGFELTTDGKNCVDHDECTTTNMCLNGMCINEDGSFKCICKPGFVLAPNGRYCTDV 659
Query: 367 DPCFRANCEYQCQPLN-QTSYLCVCAEGFA----------------------------PI 397
D C +N + S+ C C G A P
Sbjct: 660 DECQTPGICMNGHCINSEGSFRCDCPPGLAVGMDGRVCVDTHMRSTCYGGIKKGVCVRPF 719
Query: 398 PHEPHRCQMFCNQ---------TACPADCDPNTQASCECPEGYILDDGFICTDIDECE-N 447
P + + C CPA C G +D DI+EC +
Sbjct: 720 PGAVTKSECCCANPDYGFGEPCQPCPAKNSAEFHGLCSSGVGITVDG----RDINECALD 775
Query: 448 GGFC-SGVCHNLPGTFECICG----PDSALARHIGTD--------CDSG 483
C +G+C NL G++ C C PD++ I D CD+G
Sbjct: 776 PDICANGICENLRGSYRCNCNSGYEPDASGRNCIDIDECLVNRLLCDNG 824
Score = 67.0 bits (162), Expect = 4e-11
Identities = 55/176 (31%), Positives = 73/176 (41%), Gaps = 14/176 (7%)
Query: 324 EDVDDCILEPSPCPQ-RCVNTQGGFECHCYPNYDL-VDGECVEPVDPCFRANCEYQCQPL 381
+ +D C + C RC+ T + C C Y +G+C++ VD C C
Sbjct: 493 QTIDICKHHANLCLNGRCIPTVSSYRCECNMGYKQDANGDCID-VDECTSNPCTNGDCVN 551
Query: 382 NQTSYLCVCAEGFAPIPHEPHRC----QMFCNQTACPADCDPNTQAS--CECPEGYILD- 434
SY C C GF P + C + N C NT S C C G+ L
Sbjct: 552 TPGSYYCKCHAGFQRTPTK-QACIDIDECIQNGVLCKNGRCVNTDGSFQCICNAGFELTT 610
Query: 435 DGFICTDIDECENGGFC-SGVCHNLPGTFECICGPDSALARH--IGTDCDSGKVDG 487
DG C D DEC C +G+C N G+F+CIC P LA + TD D + G
Sbjct: 611 DGKNCVDHDECTTTNMCLNGMCINEDGSFKCICKPGFVLAPNGRYCTDVDECQTPG 666
Score = 63.5 bits (153), Expect = 5e-10
Identities = 76/304 (25%), Positives = 106/304 (34%), Gaps = 79/304 (25%)
Query: 224 CTAPPGAVQGHWAREAPGAWDCSVENGGCEHA---CNAIPGAPRCQCPAGAALQADGRSC 280
CT P G + +C+ CE C + G C CP G A + DG C
Sbjct: 2277 CTCPIGYALREDQKMCKDLDECAEGLHDCESRGMMCKNLIGTFMCICPPGMARRPDGEGC 2336
Query: 281 T-ASATQSCNDLCEHF-CVPNPDQPGSYSCMCETGYRLAADQHRCED------------- 325
+ ++ +CE+ CV + GSY C C G++ ++ C D
Sbjct: 2337 VDENECRTKPGICENGRCV---NIIGSYRCECNEGFQSSSSGTECLDNRQGLCFAEVLQT 2393
Query: 326 -------------------------VDDCILEPSP--------CPQRCVNTQGG---FEC 349
C L P P CP T G EC
Sbjct: 2394 ICQMASSSRNLVTKSECCCDGGRGWGHQCELCPLPGTAQYKKICPHGPGYTTDGRDIDEC 2453
Query: 350 HCYPNYDLVDGECVEPVDPCFRANCEY-QCQPLNQTSYLCVCAEGFAPIPHEPHRCQMFC 408
PN +G+C+ + FR C+ ++ TS C+ + P C C
Sbjct: 2454 KVMPNL-CTNGQCINTMG-SFRCFCKVGYTTDISGTS--CIDLD---ECSQSPKPCNYIC 2506
Query: 409 NQTACPADCDPNTQAS--CECPEGYIL-DDGFICTDIDECENGGF-CSGVCHNLPGTFEC 464
NT+ S C CP GY+L +DG C D+DEC+ C +C N G F C
Sbjct: 2507 K----------NTEGSYQCSCPRGYVLQEDGKTCKDLDECQTKQHNCQFLCVNTLGGFTC 2556
Query: 465 ICGP 468
C P
Sbjct: 2557 KCPP 2560
Score = 54.3 bits (129), Expect = 3e-07
Identities = 43/163 (26%), Positives = 60/163 (36%), Gaps = 23/163 (14%)
Query: 245 CSVENGGCEHACNAIPGAPRCQCPAGAALQADGRSCTASATQSCNDLCEHFCVPNPDQPG 304
C+ H C P P+ C G T +C D+ E +P Q G
Sbjct: 240 CATIGRAWGHPCEMCPAQPQ-PCRRGFIPNI--------RTGACQDVDECQAIPGICQGG 290
Query: 305 -------SYSCMCETGYRLAADQHRCEDVDDCILEPSPCPQ-RCVNTQGGFECHCYPNY- 355
S+ C C G++ + +CED+D+C + P C C NT G + C C Y
Sbjct: 291 NCINTVGSFECRCPAGHKQSETTQKCEDIDECSIIPGICETGECSNTVGSYFCVCPRGYV 350
Query: 356 DLVDG-ECVEP-VDPCFRANCEYQCQ---PLNQTSYLCVCAEG 393
DG C++ CF +C P T C C G
Sbjct: 351 TSTDGSRCIDQRTGMCFSGLVNGRCAQELPGRMTKMQCCCEPG 393
Score = 49.3 bits (116), Expect = 1e-05
Identities = 64/238 (26%), Positives = 88/238 (36%), Gaps = 50/238 (21%)
Query: 240 PGAWDCSVENGGCEHAC-NAIPGAPR-CQCPAGAALQADGRSCTASATQSCNDLCEHFCV 297
PG C V C ++C + P C C +G +C + + Q C+ C +
Sbjct: 105 PGGNQCIVPI--CRNSCGDGFCSRPNMCTCSSGQI----SSTCGSKSIQQCSVRCMNGGT 158
Query: 298 PNPDQPGSYSCMCETGY-----RLAADQHRCEDVDDCILEPSPCPQRCVNTQGGFECHCY 352
D C C+ GY ++ C++ CI P RC G C
Sbjct: 159 CADDH-----CQCQKGYIGTYCGQPVCENGCQNGGRCI-----GPNRCACVYGFTGPQCE 208
Query: 353 PNYDLVDGECVEPVDPCFRANCEYQCQPLNQTSYLCVCAEGFAPIPHEPHRCQMFCNQTA 412
+Y G C V+ C+ Q + T LC G A H C+M
Sbjct: 209 RDYRT--GPCFTQVN---NQMCQGQLTGIVCTKTLCCATIGRA----WGHPCEM------ 253
Query: 413 CPADCDPNTQASCECPEGYI--LDDGFICTDIDECEN-GGFCSGV-CHNLPGTFECIC 466
CPA P C G+I + G C D+DEC+ G C G C N G+FEC C
Sbjct: 254 CPAQPQP-------CRRGFIPNIRTG-ACQDVDECQAIPGICQGGNCINTVGSFECRC 303
Score = 47.8 bits (112), Expect = 3e-05
Identities = 47/173 (27%), Positives = 62/173 (35%), Gaps = 35/173 (20%)
Query: 251 GCEHACNAIPGAPRCQCP---AGAALQADGRSCTASATQSCNDLCE-------------- 293
GC++ I G RC C G + D R+ TQ N +C+
Sbjct: 183 GCQNGGRCI-GPNRCACVYGFTGPQCERDYRTGPCF-TQVNNQMCQGQLTGIVCTKTLCC 240
Query: 294 --------HFCVPNPDQPGSYSCMCETGYRLAADQHRCEDVDDCILEPSPCPQ-RCVNTQ 344
H C P QP C G+ C+DVD+C P C C+NT
Sbjct: 241 ATIGRAWGHPCEMCPAQPQP----CRRGFIPNIRTGACQDVDECQAIPGICQGGNCINTV 296
Query: 345 GGFECHCYPNYDLVDG-ECVEPVDPC--FRANCEYQCQPLNQTSYLCVCAEGF 394
G FEC C + + + E +D C CE SY CVC G+
Sbjct: 297 GSFECRCPAGHKQSETTQKCEDIDECSIIPGICETGECSNTVGSYFCVCPRGY 349
Score = 42.7 bits (99), Expect = 9e-04
Identities = 33/119 (27%), Positives = 42/119 (35%), Gaps = 14/119 (11%)
Query: 224 CTAPPGAVQGHWAREAPGAWDCSVENGGCEHA-CNAIPGAPRCQCPAGAALQADGRSCTA 282
C P G Q ++ +CS+ G CE C+ G+ C CP G DG C
Sbjct: 301 CRCPAGHKQSETTQKCEDIDECSIIPGICETGECSNTVGSYFCVCPRGYVTSTDGSRCID 360
Query: 283 SATQSC-NDLCEHFCVPN-PDQPGSYSCMCETGYRLAADQHRCEDVDDCILEPSPCPQR 339
T C + L C P + C CE G RC + P CP R
Sbjct: 361 QRTGMCFSGLVNGRCAQELPGRMTKMQCCCEPG--------RCWGIGTI---PEACPVR 408
>gi|62548862 matrilin 2 isoform b precursor [Homo sapiens]
Length = 937
Score = 129 bits (323), Expect = 1e-29
Identities = 84/248 (33%), Positives = 118/248 (47%), Gaps = 19/248 (7%)
Query: 245 CSVENGGCEHACNAIPGAPRCQCPAGAALQADGRSCTA-SATQSCNDLCEHFCVPNPDQP 303
C+ EN GCEH C G+ CQC G AL D ++CT S N C+H CV D
Sbjct: 324 CASENHGCEHECVNADGSYLCQCHEGFALNPDKKTCTKIDYCASSNHGCQHECVNTDD-- 381
Query: 304 GSYSCMCETGYRLAADQHRCEDVDDCILEPSPCPQRCVNTQGGFECHCYPNYDL-VDGEC 362
SYSC C G+ L D+ C ++ C L C CVN + + C C+ Y L +G+
Sbjct: 382 -SYSCHCLKGFTLNPDKKTCRRINYCALNKPGCEHECVNMEESYYCRCHRGYTLDPNGKT 440
Query: 363 VEPVDPCFRAN--CEYQCQPLN-QTSYLCVCAEGFAPIPHEPHRCQM--FC--NQTACPA 415
VD C + + CE C LN + S++C C+EGF I + C +C + C
Sbjct: 441 CSRVDHCAQQDHGCEQLC--LNTEDSFVCQCSEGFL-INEDLKTCSRVDYCLLSDHGCEY 497
Query: 416 DC-DPNTQASCECPEGYIL-DDGFICTDIDECENGGF-CSGVCHNLPGTFECICGPDSAL 472
C + + +C+CPEG++L DG C +D C G C C + +F C C + +
Sbjct: 498 SCVNMDRSFACQCPEGHVLRSDGKTCAKLDSCALGDHGCEHSCVSSEDSFVCQCF-EGYI 556
Query: 473 ARHIGTDC 480
R G C
Sbjct: 557 LREDGKTC 564
Score = 127 bits (319), Expect = 3e-29
Identities = 84/270 (31%), Positives = 123/270 (45%), Gaps = 40/270 (14%)
Query: 245 CSVENGGCEHACNAIPGAPRCQCPAGAALQADGRSCTA-SATQSCNDLCEHFCVPNPDQP 303
C++E+ CE C +PG+ CQC +G AL DG+ C A S N CEH CV N D
Sbjct: 283 CAMEDHNCEQLCVNVPGSFVCQCYSGYALAEDGKRCVAVDYCASENHGCEHECV-NAD-- 339
Query: 304 GSYSCMCETGYRLAADQHRCEDVDDCILEPSPCPQRCVNTQGGFECHCYPNYDL-VDGEC 362
GSY C C G+ L D+ C +D C C CVNT + CHC + L D +
Sbjct: 340 GSYLCQCHEGFALNPDKKTCTKIDYCASSNHGCQHECVNTDDSYSCHCLKGFTLNPDKKT 399
Query: 363 VEPVDPCF--RANCEYQCQPLNQTSYLCVCAEGFAPIPH------------EPHRCQMFC 408
++ C + CE++C + + SY C C G+ P+ + H C+ C
Sbjct: 400 CRRINYCALNKPGCEHECVNMEE-SYYCRCHRGYTLDPNGKTCSRVDHCAQQDHGCEQLC 458
Query: 409 NQTACPADCDPNTQASCECPEGYILDDGF-ICTDIDEC---ENGGFCSGVCHNLPGTFEC 464
T C+C EG+++++ C+ +D C ++G C C N+ +F C
Sbjct: 459 LNT--------EDSFVCQCSEGFLINEDLKTCSRVDYCLLSDHG--CEYSCVNMDRSFAC 508
Query: 465 ICGPDSALARHIGTDCDSGKVDG---GDSG 491
C P+ + R G C K+D GD G
Sbjct: 509 QC-PEGHVLRSDGKTC--AKLDSCALGDHG 535
Score = 124 bits (310), Expect = 3e-28
Identities = 79/234 (33%), Positives = 110/234 (47%), Gaps = 18/234 (7%)
Query: 245 CSVENGGCEHACNAIPGAPRCQCPAGAALQADGRSCTASATQSCND-LCEHFCVPNPDQP 303
CS C H C IPG+ C+C G L +D +C + D CE CV + P
Sbjct: 242 CSTLEHNCAHFCINIPGSYVCRCKQGYILNSDQTTCRIQDLCAMEDHNCEQLCV---NVP 298
Query: 304 GSYSCMCETGYRLAADQHRCEDVDDCILEPSPCPQRCVNTQGGFECHCYPNYDL-VDGEC 362
GS+ C C +GY LA D RC VD C E C CVN G + C C+ + L D +
Sbjct: 299 GSFVCQCYSGYALAEDGKRCVAVDYCASENHGCEHECVNADGSYLCQCHEGFALNPDKKT 358
Query: 363 VEPVDPCFRAN--CEYQCQPLNQTSYLCVCAEGFAPIPHEPHRCQM--FC--NQTACPAD 416
+D C +N C+++C + SY C C +GF P + C+ +C N+ C +
Sbjct: 359 CTKIDYCASSNHGCQHECVNTDD-SYSCHCLKGFTLNP-DKKTCRRINYCALNKPGCEHE 416
Query: 417 CDPNTQAS--CECPEGYILD-DGFICTDIDEC-ENGGFCSGVCHNLPGTFECIC 466
C N + S C C GY LD +G C+ +D C + C +C N +F C C
Sbjct: 417 C-VNMEESYYCRCHRGYTLDPNGKTCSRVDHCAQQDHGCEQLCLNTEDSFVCQC 469
Score = 112 bits (279), Expect = 1e-24
Identities = 71/196 (36%), Positives = 96/196 (48%), Gaps = 13/196 (6%)
Query: 280 CTASATQSCNDLCEHFCVPNPDQPGSYSCMCETGYRLAADQHRCEDVDDCILEPSPCPQR 339
CTA + C HFC+ + PGSY C C+ GY L +DQ C D C +E C Q
Sbjct: 237 CTAHMCSTLEHNCAHFCI---NIPGSYVCRCKQGYILNSDQTTCRIQDLCAMEDHNCEQL 293
Query: 340 CVNTQGGFECHCYPNYDLV-DGECVEPVDPCFRAN--CEYQCQPLNQTSYLCVCAEGFAP 396
CVN G F C CY Y L DG+ VD C N CE++C + SYLC C EGFA
Sbjct: 294 CVNVPGSFVCQCYSGYALAEDGKRCVAVDYCASENHGCEHECVNAD-GSYLCQCHEGFAL 352
Query: 397 IPHEPHRCQM-FC--NQTACPADC-DPNTQASCECPEGYILD-DGFICTDIDECE-NGGF 450
P + ++ +C + C +C + + SC C +G+ L+ D C I+ C N
Sbjct: 353 NPDKKTCTKIDYCASSNHGCQHECVNTDDSYSCHCLKGFTLNPDKKTCRRINYCALNKPG 412
Query: 451 CSGVCHNLPGTFECIC 466
C C N+ ++ C C
Sbjct: 413 CEHECVNMEESYYCRC 428
Score = 95.5 bits (236), Expect = 1e-19
Identities = 55/165 (33%), Positives = 80/165 (48%), Gaps = 9/165 (5%)
Query: 245 CSVENGGCEHACNAIPGAPRCQCPAGAALQADGRSCTASATQSCNDL-CEHFCVPNPDQP 303
C + + GCE++C + + CQCP G L++DG++C + + D CEH CV + D
Sbjct: 488 CLLSDHGCEYSCVNMDRSFACQCPEGHVLRSDGKTCAKLDSCALGDHGCEHSCVSSED-- 545
Query: 304 GSYSCMCETGYRLAADQHRCEDVDDCILEPSPCPQRCVNTQGGFECHCYPNYDLV-DGEC 362
S+ C C GY L D C D C C CVN+ + C C + L DG+
Sbjct: 546 -SFVCQCFEGYILREDGKTCRRKDVCQAIDHGCEHICVNSDDSYTCECLEGFRLAEDGKR 604
Query: 363 VEPVDPCFRAN--CEYQCQPLNQTSYLCVCAEGFAPIPHEPHRCQ 405
D C + CE+ C N SY+C C+EGF + + RC+
Sbjct: 605 CRRKDVCKSTHHGCEHICVN-NGNSYICKCSEGFV-LAEDGRRCK 647
Score = 83.6 bits (205), Expect = 5e-16
Identities = 50/154 (32%), Positives = 70/154 (45%), Gaps = 10/154 (6%)
Query: 224 CTAPPGAVQGHWAREAPGAWDCSVENGGCEHACNAIPGAPRCQCPAGAALQADGRSCTAS 283
C P G V + C++ + GCEH+C + + CQC G L+ DG++C
Sbjct: 508 CQCPEGHVLRSDGKTCAKLDSCALGDHGCEHSCVSSEDSFVCQCFEGYILREDGKTCRRK 567
Query: 284 -ATQSCNDLCEHFCVPNPDQPGSYSCMCETGYRLAADQHRCEDVDDCILEPSPCPQRCVN 342
Q+ + CEH CV + D SY+C C G+RLA D RC D C C CVN
Sbjct: 568 DVCQAIDHGCEHICVNSDD---SYTCECLEGFRLAEDGKRCRRKDVCKSTHHGCEHICVN 624
Query: 343 TQGGFECHCYPNYDLVDG-----ECVE-PVDPCF 370
+ C C + L + +C E P+D F
Sbjct: 625 NGNSYICKCSEGFVLAEDGRRCKKCTEGPIDLVF 658
>gi|62548860 matrilin 2 isoform a precursor [Homo sapiens]
Length = 956
Score = 129 bits (323), Expect = 1e-29
Identities = 84/248 (33%), Positives = 118/248 (47%), Gaps = 19/248 (7%)
Query: 245 CSVENGGCEHACNAIPGAPRCQCPAGAALQADGRSCTA-SATQSCNDLCEHFCVPNPDQP 303
C+ EN GCEH C G+ CQC G AL D ++CT S N C+H CV D
Sbjct: 324 CASENHGCEHECVNADGSYLCQCHEGFALNPDKKTCTKIDYCASSNHGCQHECVNTDD-- 381
Query: 304 GSYSCMCETGYRLAADQHRCEDVDDCILEPSPCPQRCVNTQGGFECHCYPNYDL-VDGEC 362
SYSC C G+ L D+ C ++ C L C CVN + + C C+ Y L +G+
Sbjct: 382 -SYSCHCLKGFTLNPDKKTCRRINYCALNKPGCEHECVNMEESYYCRCHRGYTLDPNGKT 440
Query: 363 VEPVDPCFRAN--CEYQCQPLN-QTSYLCVCAEGFAPIPHEPHRCQM--FC--NQTACPA 415
VD C + + CE C LN + S++C C+EGF I + C +C + C
Sbjct: 441 CSRVDHCAQQDHGCEQLC--LNTEDSFVCQCSEGFL-INEDLKTCSRVDYCLLSDHGCEY 497
Query: 416 DC-DPNTQASCECPEGYIL-DDGFICTDIDECENGGF-CSGVCHNLPGTFECICGPDSAL 472
C + + +C+CPEG++L DG C +D C G C C + +F C C + +
Sbjct: 498 SCVNMDRSFACQCPEGHVLRSDGKTCAKLDSCALGDHGCEHSCVSSEDSFVCQCF-EGYI 556
Query: 473 ARHIGTDC 480
R G C
Sbjct: 557 LREDGKTC 564
Score = 127 bits (319), Expect = 3e-29
Identities = 84/270 (31%), Positives = 123/270 (45%), Gaps = 40/270 (14%)
Query: 245 CSVENGGCEHACNAIPGAPRCQCPAGAALQADGRSCTA-SATQSCNDLCEHFCVPNPDQP 303
C++E+ CE C +PG+ CQC +G AL DG+ C A S N CEH CV N D
Sbjct: 283 CAMEDHNCEQLCVNVPGSFVCQCYSGYALAEDGKRCVAVDYCASENHGCEHECV-NAD-- 339
Query: 304 GSYSCMCETGYRLAADQHRCEDVDDCILEPSPCPQRCVNTQGGFECHCYPNYDL-VDGEC 362
GSY C C G+ L D+ C +D C C CVNT + CHC + L D +
Sbjct: 340 GSYLCQCHEGFALNPDKKTCTKIDYCASSNHGCQHECVNTDDSYSCHCLKGFTLNPDKKT 399
Query: 363 VEPVDPCF--RANCEYQCQPLNQTSYLCVCAEGFAPIPH------------EPHRCQMFC 408
++ C + CE++C + + SY C C G+ P+ + H C+ C
Sbjct: 400 CRRINYCALNKPGCEHECVNMEE-SYYCRCHRGYTLDPNGKTCSRVDHCAQQDHGCEQLC 458
Query: 409 NQTACPADCDPNTQASCECPEGYILDDGF-ICTDIDEC---ENGGFCSGVCHNLPGTFEC 464
T C+C EG+++++ C+ +D C ++G C C N+ +F C
Sbjct: 459 LNT--------EDSFVCQCSEGFLINEDLKTCSRVDYCLLSDHG--CEYSCVNMDRSFAC 508
Query: 465 ICGPDSALARHIGTDCDSGKVDG---GDSG 491
C P+ + R G C K+D GD G
Sbjct: 509 QC-PEGHVLRSDGKTC--AKLDSCALGDHG 535
Score = 124 bits (310), Expect = 3e-28
Identities = 79/234 (33%), Positives = 110/234 (47%), Gaps = 18/234 (7%)
Query: 245 CSVENGGCEHACNAIPGAPRCQCPAGAALQADGRSCTASATQSCND-LCEHFCVPNPDQP 303
CS C H C IPG+ C+C G L +D +C + D CE CV + P
Sbjct: 242 CSTLEHNCAHFCINIPGSYVCRCKQGYILNSDQTTCRIQDLCAMEDHNCEQLCV---NVP 298
Query: 304 GSYSCMCETGYRLAADQHRCEDVDDCILEPSPCPQRCVNTQGGFECHCYPNYDL-VDGEC 362
GS+ C C +GY LA D RC VD C E C CVN G + C C+ + L D +
Sbjct: 299 GSFVCQCYSGYALAEDGKRCVAVDYCASENHGCEHECVNADGSYLCQCHEGFALNPDKKT 358
Query: 363 VEPVDPCFRAN--CEYQCQPLNQTSYLCVCAEGFAPIPHEPHRCQM--FC--NQTACPAD 416
+D C +N C+++C + SY C C +GF P + C+ +C N+ C +
Sbjct: 359 CTKIDYCASSNHGCQHECVNTDD-SYSCHCLKGFTLNP-DKKTCRRINYCALNKPGCEHE 416
Query: 417 CDPNTQAS--CECPEGYILD-DGFICTDIDEC-ENGGFCSGVCHNLPGTFECIC 466
C N + S C C GY LD +G C+ +D C + C +C N +F C C
Sbjct: 417 C-VNMEESYYCRCHRGYTLDPNGKTCSRVDHCAQQDHGCEQLCLNTEDSFVCQC 469
Score = 112 bits (279), Expect = 1e-24
Identities = 71/196 (36%), Positives = 96/196 (48%), Gaps = 13/196 (6%)
Query: 280 CTASATQSCNDLCEHFCVPNPDQPGSYSCMCETGYRLAADQHRCEDVDDCILEPSPCPQR 339
CTA + C HFC+ + PGSY C C+ GY L +DQ C D C +E C Q
Sbjct: 237 CTAHMCSTLEHNCAHFCI---NIPGSYVCRCKQGYILNSDQTTCRIQDLCAMEDHNCEQL 293
Query: 340 CVNTQGGFECHCYPNYDLV-DGECVEPVDPCFRAN--CEYQCQPLNQTSYLCVCAEGFAP 396
CVN G F C CY Y L DG+ VD C N CE++C + SYLC C EGFA
Sbjct: 294 CVNVPGSFVCQCYSGYALAEDGKRCVAVDYCASENHGCEHECVNAD-GSYLCQCHEGFAL 352
Query: 397 IPHEPHRCQM-FC--NQTACPADC-DPNTQASCECPEGYILD-DGFICTDIDECE-NGGF 450
P + ++ +C + C +C + + SC C +G+ L+ D C I+ C N
Sbjct: 353 NPDKKTCTKIDYCASSNHGCQHECVNTDDSYSCHCLKGFTLNPDKKTCRRINYCALNKPG 412
Query: 451 CSGVCHNLPGTFECIC 466
C C N+ ++ C C
Sbjct: 413 CEHECVNMEESYYCRC 428
Score = 95.5 bits (236), Expect = 1e-19
Identities = 55/165 (33%), Positives = 80/165 (48%), Gaps = 9/165 (5%)
Query: 245 CSVENGGCEHACNAIPGAPRCQCPAGAALQADGRSCTASATQSCNDL-CEHFCVPNPDQP 303
C + + GCE++C + + CQCP G L++DG++C + + D CEH CV + D
Sbjct: 488 CLLSDHGCEYSCVNMDRSFACQCPEGHVLRSDGKTCAKLDSCALGDHGCEHSCVSSED-- 545
Query: 304 GSYSCMCETGYRLAADQHRCEDVDDCILEPSPCPQRCVNTQGGFECHCYPNYDLV-DGEC 362
S+ C C GY L D C D C C CVN+ + C C + L DG+
Sbjct: 546 -SFVCQCFEGYILREDGKTCRRKDVCQAIDHGCEHICVNSDDSYTCECLEGFRLAEDGKR 604
Query: 363 VEPVDPCFRAN--CEYQCQPLNQTSYLCVCAEGFAPIPHEPHRCQ 405
D C + CE+ C N SY+C C+EGF + + RC+
Sbjct: 605 CRRKDVCKSTHHGCEHICVN-NGNSYICKCSEGFV-LAEDGRRCK 647
Score = 83.6 bits (205), Expect = 5e-16
Identities = 50/154 (32%), Positives = 70/154 (45%), Gaps = 10/154 (6%)
Query: 224 CTAPPGAVQGHWAREAPGAWDCSVENGGCEHACNAIPGAPRCQCPAGAALQADGRSCTAS 283
C P G V + C++ + GCEH+C + + CQC G L+ DG++C
Sbjct: 508 CQCPEGHVLRSDGKTCAKLDSCALGDHGCEHSCVSSEDSFVCQCFEGYILREDGKTCRRK 567
Query: 284 -ATQSCNDLCEHFCVPNPDQPGSYSCMCETGYRLAADQHRCEDVDDCILEPSPCPQRCVN 342
Q+ + CEH CV + D SY+C C G+RLA D RC D C C CVN
Sbjct: 568 DVCQAIDHGCEHICVNSDD---SYTCECLEGFRLAEDGKRCRRKDVCKSTHHGCEHICVN 624
Query: 343 TQGGFECHCYPNYDLVDG-----ECVE-PVDPCF 370
+ C C + L + +C E P+D F
Sbjct: 625 NGNSYICKCSEGFVLAEDGRRCKKCTEGPIDLVF 658
>gi|24430141 fibrillin 1 precursor [Homo sapiens]
Length = 2871
Score = 125 bits (315), Expect = 8e-29
Identities = 87/239 (36%), Positives = 112/239 (46%), Gaps = 23/239 (9%)
Query: 244 DCSVENGGCEHACNAIPGAPRCQCPAGAALQADGRSCTASATQSCND---LCEHFCVPNP 300
+CS+ NGGCE C G+ C C G AL D RSCT C D +C+ N
Sbjct: 1200 ECSIMNGGCETFCTNSEGSYECSCQPGFALMPDQRSCT--DIDECEDNPNICDGGQCTN- 1256
Query: 301 DQPGSYSCMCETGYRLAADQHRCEDVDDCILEPSPC-PQRCVNTQGGFECHCYPNYDLVD 359
PG Y C+C G+ + D C DV++C L P+ C C NT+G F CHC Y
Sbjct: 1257 -IPGEYRCLCYDGFMASEDMKTCVDVNECDLNPNICLSGTCENTKGSFICHCDMGYSGKK 1315
Query: 360 GE--CVEPVDPC--FRANCEYQCQPLNQT-SYLCVCAEGFAPIP---HEPHRCQMFCNQT 411
G+ C + ++ C NC N S+ C C+ G+ + C +
Sbjct: 1316 GKTGCTD-INECEIGAHNCGKHAVCTNTAGSFKCSCSPGWIGDGIKCTDLDECSNGTHMC 1374
Query: 412 ACPADCDPNTQAS--CECPEGYILDDGFICTDIDEC-ENGGFC-SGVCHNLPGTFECIC 466
+ ADC NT S C C EGY DGF CTD+DEC EN C +G C N PG + C C
Sbjct: 1375 SQHADC-KNTMGSYRCLCKEGY-TGDGFTCTDLDECSENLNLCGNGQCLNAPGGYRCEC 1431
Score = 114 bits (285), Expect = 2e-25
Identities = 87/271 (32%), Positives = 113/271 (41%), Gaps = 60/271 (22%)
Query: 249 NGGCEHACNAIPGAPRCQCPAGAALQADGRSCTASATQSCNDLCEHFCVPNPDQPGSYSC 308
NG C +A PG RC+C G ADG++C S ++C N PG + C
Sbjct: 1417 NGQCLNA----PGGYRCECDMGFVPSADGKACEDIDECSLPNICVFGTCHN--LPGLFRC 1470
Query: 309 MCETGYRLAADQHRCEDVDDCILEPSPC-PQRCVNTQGGFECHCYPNYDL-------VD- 359
CE GY L C DV++C L+P+ C CVNT G + C C P+++L VD
Sbjct: 1471 ECEIGYELDRSGGNCTDVNEC-LDPTTCISGNCVNTPGSYICDCPPDFELNPTRVGCVDT 1529
Query: 360 --GECVEPVDP----------------------------CFRANCEYQCQPLNQTSY--L 387
G C + P + CE C +N + Y L
Sbjct: 1530 RSGNCYLDIRPRGDNGDTACSNEIGVGVSKASCCCSLGKAWGTPCE-MCPAVNTSEYKIL 1588
Query: 388 CVCAEGFAPIP-----HEPHRCQMFCNQTACPADCDPNTQAS--CECPEGYIL-DDGFIC 439
C EGF P P + CQ C NT S C CP GY L +D +C
Sbjct: 1589 CPGGEGFRPNPITVILEDIDECQEL--PGLCQGGKCINTFGSFQCRCPTGYYLNEDTRVC 1646
Query: 440 TDIDECENGGFCS-GVCHNLPGTFECICGPD 469
D++ECE G C G C+N G + CIC PD
Sbjct: 1647 DDVNECETPGICGPGTCYNTVGNYTCICPPD 1677
Score = 105 bits (261), Expect = 1e-22
Identities = 75/232 (32%), Positives = 104/232 (44%), Gaps = 27/232 (11%)
Query: 256 CNAIPGAPRCQCPAGAALQADGRSCTASATQSCNDLCEHFCVPNP---DQPGSYSCMCET 312
C+ G+ RC+CP G L + +C C +L H C PN + G Y C C
Sbjct: 1129 CHNTEGSYRCECPPGHQLSPNISACID--INEC-ELSAHLC-PNGRCVNLIGKYQCACNP 1184
Query: 313 GYRLAADQHRCEDVDDCILEPSPCPQRCVNTQGGFECHCYPNYDLV-DGECVEPVDPCFR 371
GY D+ C D+D+C + C C N++G +EC C P + L+ D +D C
Sbjct: 1185 GYHSTPDRLFCVDIDECSIMNGGCETFCTNSEGSYECSCQPGFALMPDQRSCTDIDEC-E 1243
Query: 372 AN---CE-YQCQPLNQTSYLCVCAEGFAPIPH-----EPHRCQMFCNQTACPADCDPNTQ 422
N C+ QC + Y C+C +GF + + C + N C + NT+
Sbjct: 1244 DNPNICDGGQCTNI-PGEYRCLCYDGFMASEDMKTCVDVNECDL--NPNICLSGTCENTK 1300
Query: 423 AS--CECPEGYILDDGFI-CTDIDECENGGFCSG---VCHNLPGTFECICGP 468
S C C GY G CTDI+ECE G G VC N G+F+C C P
Sbjct: 1301 GSFICHCDMGYSGKKGKTGCTDINECEIGAHNCGKHAVCTNTAGSFKCSCSP 1352
Score = 104 bits (259), Expect = 3e-22
Identities = 80/296 (27%), Positives = 118/296 (39%), Gaps = 82/296 (27%)
Query: 256 CNAIPGAPRCQCPAGAALQADGRSCTASATQSCNDLCEHFCVPNPDQPGSYSCMCETGYR 315
C G+ C C AG + DG++C S ++C + N D GS+ C+C+ G++
Sbjct: 546 CINTDGSFHCVCNAGFHVTRDGKNCEDMDECSIRNMCLNGMCINED--GSFKCICKPGFQ 603
Query: 316 LAADQHRCEDVDDCILEPSPCPQRCVNTQGGFECHCYPNYDL-------VD--------- 359
LA+D C+D+++C RCVNT G + C C+P + VD
Sbjct: 604 LASDGRYCKDINECETPGICMNGRCVNTDGSYRCECFPGLAVGLDGRVCVDTHMRSTCYG 663
Query: 360 ----GECVEPV------DPCFRANCEYQ----CQP------------------------- 380
G+C++P+ C A+ EY CQP
Sbjct: 664 GYKRGQCIKPLFGAVTKSECCCASTEYAFGEPCQPCPAQNSAEYQALCSSGPGMTSAGSD 723
Query: 381 LNQTS-----------------YLCVCAEGFAPIPHEPHRC----QMFCNQTACPADCDP 419
+N+ + Y C+C G+ + C + N C
Sbjct: 724 INECALDPDICPNGICENLRGTYKCICNSGYE-VDSTGKNCVDINECVLNSLLCDNGQCR 782
Query: 420 NTQAS--CECPEGYILD-DGFICTDIDECENGGFCSGVCHNLPGTFECICGPDSAL 472
NT S C CP+G+I D C DIDECE+ +GVC N PG+F C C +S L
Sbjct: 783 NTPGSFVCTCPKGFIYKPDLKTCEDIDECESSPCINGVCKNSPGSFICECSSESTL 838
Score = 102 bits (255), Expect = 7e-22
Identities = 78/280 (27%), Positives = 110/280 (39%), Gaps = 49/280 (17%)
Query: 244 DCSVENGGCEHA-CNAIPGAPRCQCPAGAALQADGRSCTA-----SATQSCNDLCEHFCV 297
+C V + C + C G+ C C G G SC A + CN +C++
Sbjct: 2405 ECKVIHDVCRNGECVNDRGSYHCICKTGYTPDITGTSCVDLNECNQAPKPCNFICKN--- 2461
Query: 298 PNPDQPGSYSCMCETGYRLAADQHRCEDVDDCILEPSPCPQRCVNTQGGFECHCYPNYD- 356
GSY C C GY L D C+D+D+C + C CVNT GGF C C P +
Sbjct: 2462 ----TEGSYQCSCPKGYILQEDGRSCKDLDECATKQHNCQFLCVNTIGGFTCKCPPGFTQ 2517
Query: 357 -----LVDGECVEPVDPCFRANCEYQCQPLNQTSYLCVCAEGFA-----------PIPHE 400
+ + EC ++ C + CQ S+ C C GF+
Sbjct: 2518 HHTSCIDNNECTSDINLC---GSKGICQN-TPGSFTCECQRGFSLDQTGSSCEDVDECEG 2573
Query: 401 PHRCQMFCNQTACPADCDPNTQASCECPEGYILDDGF-ICTDIDECENGGFCSGV-CHNL 458
HRCQ C C CP+GY+ + C D +EC + C G CHN
Sbjct: 2574 NHRCQHGCQNII--------GGYRCSCPQGYLQHYQWNQCVDENECLSAHICGGASCHNT 2625
Query: 459 PGTFECICGPDSALARHIGTDCDSGKVDGGDSGSGEPPPS 498
G+++C+C + G G D + GS + P S
Sbjct: 2626 LGSYKCMCPAGFQYEQFSG-----GCQDINECGSAQAPCS 2660
Score = 101 bits (251), Expect = 2e-21
Identities = 87/295 (29%), Positives = 116/295 (39%), Gaps = 64/295 (21%)
Query: 224 CTAPPG-AVQGHWAREAPGAWDCSVENGGCE-HACNAIPGAPRCQCPAGAALQADGRSCT 281
C PPG ++Q + +C E C C+ G+ +C CP G +L + GR C
Sbjct: 1998 CICPPGYSLQNEKCEDID---ECVEEPEICALGTCSNTEGSFKCLCPEGFSLSSSGRRCQ 2054
Query: 282 ASATQSC-------------------------------NDLCEHFCVPNPDQPGSYSCMC 310
C D CE C PD+ C
Sbjct: 2055 DLRMSYCYAKFEGGKCSSPKSRNHSKQECCCALKGEGWGDPCE-LCPTEPDEAFRQICPY 2113
Query: 311 ETGYRLAADQHRCEDVDDCILEPSPCPQ-RCVNTQGGFECHCYPNYDLVDGECVEPVD-- 367
+G + D D+D+C EP C +C+NT G + C C Y L ECV+ +
Sbjct: 2114 GSGIIVGPDDSAV-DMDEC-KEPDVCKHGQCINTDGSYRCECPFGYILAGNECVDTDECS 2171
Query: 368 ---PCFRANCEYQCQPLNQTSYLCVCAEGFAPIP----HEPHRCQMFCNQTACPADCDPN 420
PC C+ + C C EGF P P + + C N C C N
Sbjct: 2172 VGNPCGNGTCKNVIG-----GFECTCEEGFEPGPMMTCEDINECAQ--NPLLCAFRC-VN 2223
Query: 421 TQAS--CECPEGYIL-DDGFICTDIDECENGGF-CSGV---CHNLPGTFECICGP 468
T S C+CP GY+L +D +C D DECE G C+ C NL GT+ CICGP
Sbjct: 2224 TYGSYECKCPVGYVLREDRRMCKDEDECEEGKHDCTEKQMECKNLIGTYMCICGP 2278
Score = 96.3 bits (238), Expect = 7e-20
Identities = 72/236 (30%), Positives = 102/236 (43%), Gaps = 27/236 (11%)
Query: 253 EHACNAIPGAPRCQCPAGAALQADGRSCTASATQSCNDLCEHFCVPNPDQPGSYSCMCET 312
E C PG + G D C + LC H N GS+ C C++
Sbjct: 1005 EELCPRGPGFATKEITNGKPFFKDINEC-----KMIPSLCTHGKCRNTI--GSFKCRCDS 1057
Query: 313 GYRLAADQHRCEDVDDCILEPSPCPQ-RCVNTQGGFECHCYPNYD---LVDGECVEPVDP 368
G+ L +++ C D+D+C + P C + +CVNT G FEC C Y+ ++ C++ +D
Sbjct: 1058 GFALDSEERNCTDIDECRISPDLCGRGQCVNTPGDFECKCDEGYESGFMMMKNCMD-IDE 1116
Query: 369 CFR--ANCEYQCQPLNQTSYLCVCAEGFAPIPH-----EPHRCQMFCNQTACPADCDPNT 421
C R C + SY C C G P+ + + C++ + CP N
Sbjct: 1117 CQRDPLLCRGGVCHNTEGSYRCECPPGHQLSPNISACIDINECELSAH--LCPNGRCVNL 1174
Query: 422 --QASCECPEGY-ILDDGFICTDIDECE--NGGFCSGVCHNLPGTFECICGPDSAL 472
+ C C GY D C DIDEC NGG C C N G++EC C P AL
Sbjct: 1175 IGKYQCACNPGYHSTPDRLFCVDIDECSIMNGG-CETFCTNSEGSYECSCQPGFAL 1229
Score = 94.7 bits (234), Expect = 2e-19
Identities = 77/288 (26%), Positives = 110/288 (38%), Gaps = 53/288 (18%)
Query: 249 NGGCEHACNAIPGAPRCQCPAGAALQADGRSCTASATQSCN-DLCEHF-CVPNPDQPGSY 306
NG C + G+ C+C G L + S N +LC + C+ + GS+
Sbjct: 1902 NGTCRNTI----GSFNCRCNHGFILSHNNDCIDVDECASGNGNLCRNGQCI---NTVGSF 1954
Query: 307 SCMCETGYRLAADQHRCEDVDDCILEPSPC-PQRCVNTQGGFECHCYPNYDLVDGECVEP 365
C C GY +A D C D+++C+LEP C P C N G + C C P Y L + +C E
Sbjct: 1955 QCQCNEGYEVAPDGRTCVDINECLLEPRKCAPGTCQNLDGSYRCICPPGYSLQNEKC-ED 2013
Query: 366 VDPCFRAN--CEYQCQPLNQTSYLCVCAEGFAPIPHEPHRCQ----MFCNQT-------- 411
+D C C + S+ C+C EGF+ + RCQ +C
Sbjct: 2014 IDECVEEPEICALGTCSNTEGSFKCLCPEGFS-LSSSGRRCQDLRMSYCYAKFEGGKCSS 2072
Query: 412 -------------------------ACPADCDPNTQASCECPEGYILDDGFICTDIDECE 446
CP + D + C G I+ D+DEC+
Sbjct: 2073 PKSRNHSKQECCCALKGEGWGDPCELCPTEPDEAFRQICPYGSGIIVGPDDSAVDMDECK 2132
Query: 447 NGGFCS-GVCHNLPGTFECICGPDSALARHIGTDCDSGKVDGGDSGSG 493
C G C N G++ C C LA + D D V G G+G
Sbjct: 2133 EPDVCKHGQCINTDGSYRCECPFGYILAGNECVDTDECSV-GNPCGNG 2179
Score = 94.7 bits (234), Expect = 2e-19
Identities = 87/287 (30%), Positives = 122/287 (42%), Gaps = 40/287 (13%)
Query: 244 DCSVENGGCEHACNAIPGAPRCQCPAGAALQADGRSCT---ASATQSCNDLCEHFCVPNP 300
+C+ C C G+ +C CP G LQ DGRSC AT+ N C+ CV
Sbjct: 2447 ECNQAPKPCNFICKNTEGSYQCSCPKGYILQEDGRSCKDLDECATKQHN--CQFLCV--- 2501
Query: 301 DQPGSYSCMCETGYRLAADQHR--CEDVDDCILEPSPCPQR--CVNTQGGFECHCYPNYD 356
+ G ++C C G+ QH C D ++C + + C + C NT G F C C +
Sbjct: 2502 NTIGGFTCKCPPGFT----QHHTSCIDNNECTSDINLCGSKGICQNTPGSFTCECQRGFS 2557
Query: 357 LVD-GECVEPVDPCF-RANCEYQCQPLNQTSYLCVCAEGFAPIPHEPHRCQMFCNQTAC- 413
L G E VD C C++ CQ + Y C C +G+ + ++ ++ C
Sbjct: 2558 LDQTGSSCEDVDECEGNHRCQHGCQNIIG-GYRCSCPQGYL----QHYQWNQCVDENECL 2612
Query: 414 ------PADCDPNTQAS--CECPEGYILDD-GFICTDIDECENGGF-CSGVCHNLPGTFE 463
A C NT S C CP G+ + C DI+EC + CS C N G +
Sbjct: 2613 SAHICGGASCH-NTLGSYKCMCPAGFQYEQFSGGCQDINECGSAQAPCSYGCSNTEGGYL 2671
Query: 464 CICGPDSALARHIGTDCDSGKVDGGDSGSGEPPPS-PTPGSTLTPPA 509
C C P R C SG G G+ EPP S ++L+P A
Sbjct: 2672 CGCPP--GYFRIGQGHCVSGM--GMGRGNPEPPVSGEMDDNSLSPEA 2714
Score = 90.9 bits (224), Expect = 3e-18
Identities = 75/254 (29%), Positives = 109/254 (42%), Gaps = 23/254 (9%)
Query: 244 DCSVENGGCEHA-CNAIPGAPRCQCPAGAALQADGRSCTASATQSCNDLCEHF--CVPNP 300
+C G CE+ C + G+ RC+CP G C +C+ C+
Sbjct: 1769 ECREIPGVCENGVCINMVGSFRCECPVGFFYNDKLLVCEDIDECQNGPVCQRNAECI--- 1825
Query: 301 DQPGSYSCMCETGYRLAADQHRCEDVDDCILEPSPCPQ-RCVNTQGGFECHCYPNYDLVD 359
+ GSY C C+ GYR + +C D ++C P+ C +C++T G F C C+ + D
Sbjct: 1826 NTAGSYRCDCKPGYRFTSTG-QCNDRNECQEIPNICSHGQCIDTVGSFYCLCHTGFKTND 1884
Query: 360 GE--CVEPVDPCFRANCEYQCQPLNQTSYLCVCAEGFAPIPH-----EPHRCQMFCNQTA 412
+ C++ ++ C R C S+ C C GF + H + C N
Sbjct: 1885 DQTMCLD-INECERDACGNGTCRNTIGSFNCRCNHGFI-LSHNNDCIDVDECASG-NGNL 1941
Query: 413 CPADCDPNTQAS--CECPEGY-ILDDGFICTDIDEC--ENGGFCSGVCHNLPGTFECICG 467
C NT S C+C EGY + DG C DI+EC E G C NL G++ CIC
Sbjct: 1942 CRNGQCINTVGSFQCQCNEGYEVAPDGRTCVDINECLLEPRKCAPGTCQNLDGSYRCICP 2001
Query: 468 PDSALARHIGTDCD 481
P +L D D
Sbjct: 2002 PGYSLQNEKCEDID 2015
Score = 89.4 bits (220), Expect = 8e-18
Identities = 89/324 (27%), Positives = 134/324 (41%), Gaps = 48/324 (14%)
Query: 160 VKADGFLC-EFHFPATC-----RPLAVEP--GAAAAAVSITYGTPFAARGADFQALPVGS 211
V DG +C + H +TC R ++P GA + T +A G Q P +
Sbjct: 645 VGLDGRVCVDTHMRSTCYGGYKRGQCIKPLFGAVTKSECCCASTEYAF-GEPCQPCPAQN 703
Query: 212 SAAVAPLGLQLMCTAPPGAVQGHWAREAPGAWDCSVENGGCEHA-CNAIPGAPRCQCPAG 270
SA Q +C++ PG +C+++ C + C + G +C C +G
Sbjct: 704 SAEY-----QALCSSGPGMTSA-----GSDINECALDPDICPNGICENLRGTYKCICNSG 753
Query: 271 AALQADGRSCTASATQSCNDL-CEHFCVPNPDQPGSYSCMCETGYRLAADQHRCEDVDDC 329
+ + G++C N L C++ N PGS+ C C G+ D CED+D+C
Sbjct: 754 YEVDSTGKNCVDINECVLNSLLCDNGQCRNT--PGSFVCTCPKGFIYKPDLKTCEDIDEC 811
Query: 330 ILEPSPCPQR-CVNTQGGFECHCYPNYDLVDGE--CVEPVD-PCFRANCEYQCQ-PLNQT 384
E SPC C N+ G F C C L + C+E + C++ + +C+ +N
Sbjct: 812 --ESSPCINGVCKNSPGSFICECSSESTLDPTKTICIETIKGTCWQTVIDGRCEININGA 869
Query: 385 SYLCVCAEGFAPIPHEPHRCQMFCNQTACPADCDPNTQASCECPEGYILDDGFICTDIDE 444
+ C P C T C D C +GY G C DIDE
Sbjct: 870 TLKSQCCSSLGAAWGSP------C--TLCQVDPI--------CGKGYSRIKGTQCEDIDE 913
Query: 445 CE-NGGFC-SGVCHNLPGTFECIC 466
CE G C +G+C N G+F+C C
Sbjct: 914 CEVFPGVCKNGLCVNTRGSFKCQC 937
Score = 84.7 bits (208), Expect = 2e-16
Identities = 68/252 (26%), Positives = 97/252 (38%), Gaps = 53/252 (21%)
Query: 267 CPAGAALQADGRSCTASATQSCNDL---CEHFCVPNPDQPGSYSCMCETGYRLAADQHRC 323
CP G + + + C +L C+ N GS+ C C TGY L D C
Sbjct: 1589 CPGGEGFRPNPITVILEDIDECQELPGLCQGGKCINTF--GSFQCRCPTGYYLNEDTRVC 1646
Query: 324 EDVDDCILEPSPCPQRCVNTQGGFECHCYPNYDLVDG--ECVE-PVDPCFR------ANC 374
+DV++C P C NT G + C C P+Y V+G C++ C+R C
Sbjct: 1647 DDVNECETPGICGPGTCYNTVGNYTCICPPDYMQVNGGNNCMDMRRSLCYRNYYADNQTC 1706
Query: 375 EYQCQPLNQTSYLCVCAEGF----------APIPHEPHRCQMFCNQ---------TACPA 415
+ + N T +C C+ PIP + +Q T P
Sbjct: 1707 DGELL-FNMTKKMCCCSYNIGRAWNKPCEQCPIPSTDEFATLCGSQRPGFVIDIYTGLPV 1765
Query: 416 DCDPNTQA----------------SCECPEGYILDDG-FICTDIDECENGGFC--SGVCH 456
D D + CECP G+ +D +C DIDEC+NG C + C
Sbjct: 1766 DIDECREIPGVCENGVCINMVGSFRCECPVGFFYNDKLLVCEDIDECQNGPVCQRNAECI 1825
Query: 457 NLPGTFECICGP 468
N G++ C C P
Sbjct: 1826 NTAGSYRCDCKP 1837
Score = 81.6 bits (200), Expect = 2e-15
Identities = 66/221 (29%), Positives = 90/221 (40%), Gaps = 39/221 (17%)
Query: 252 CEHA-CNAIPGAPRCQCPAGAALQADGRSCTASATQSCNDLCEHFCVPNPDQPGSYSCMC 310
C+H C G+ RC+CP G L G C + S + C + N G + C C
Sbjct: 2137 CKHGQCINTDGSYRCECPFGYILA--GNECVDTDECSVGNPCGNGTCKNVI--GGFECTC 2192
Query: 311 ETGYRLAADQHRCEDVDDCILEPSPCPQRCVNTQGGFECHCYPNYDL--------VDGEC 362
E G+ CED+++C P C RCVNT G +EC C Y L + EC
Sbjct: 2193 EEGFE-PGPMMTCEDINECAQNPLLCAFRCVNTYGSYECKCPVGYVLREDRRMCKDEDEC 2251
Query: 363 VEPVDPCFRANCEYQCQPLNQTSYLCVCAEGFAPIPH-----EPHRCQM---FCNQTACP 414
E C E C+ L T Y+C+C G+ P + + CQ C C
Sbjct: 2252 EEGKHDCTEKQME--CKNLIGT-YMCICGPGYQRRPDGEGCVDENECQTKPGICENGRC- 2307
Query: 415 ADCDPNTQAS--CECPEGYILDDGFICTDIDEC--ENGGFC 451
NT+ S CEC +G+ + DEC G+C
Sbjct: 2308 ----LNTRGSYTCECNDGFTAS-----PNQDECLDNREGYC 2339
Score = 79.0 bits (193), Expect = 1e-14
Identities = 85/329 (25%), Positives = 118/329 (35%), Gaps = 75/329 (22%)
Query: 244 DCSVENGGCEHA-CNAIPGAPRCQCPAGAALQADGRSCTASATQSC--NDLCEHFCVPNP 300
+C V G C++ C G+ +CQCP+G L A GR C ++C E +P
Sbjct: 913 ECEVFPGVCKNGLCVNTRGSFKCQCPSGMTLDATGRICLDIRLETCFLRYEDEECTLPIA 972
Query: 301 DQPGSYSCMCETGYRLAADQ-HRC------------------------------EDVDDC 329
+ +C C G ++ C +D+++C
Sbjct: 973 GRHRMDACCCSVGAAWGTEECEECPMRNTPEYEELCPRGPGFATKEITNGKPFFKDINEC 1032
Query: 330 ILEPSPCPQ-RCVNTQGGFECHCYPNYDLVD--------GECVEPVDPCFRANCEYQCQP 380
+ PS C +C NT G F+C C + L EC D C R C
Sbjct: 1033 KMIPSLCTHGKCRNTIGSFKCRCDSGFALDSEERNCTDIDECRISPDLCGRGQCVN---- 1088
Query: 381 LNQTSYLCVCAEGF---------APIPHEPHRCQMFCNQTACPADCDPNTQAS--CECPE 429
+ C C EG+ E R + C C NT+ S CECP
Sbjct: 1089 -TPGDFECKCDEGYESGFMMMKNCMDIDECQRDPLLCRGGVC-----HNTEGSYRCECPP 1142
Query: 430 GYILDDGF-ICTDIDECE-NGGFC-SGVCHNLPGTFECICGP--DSALARHIGTDCDSGK 484
G+ L C DI+ECE + C +G C NL G ++C C P S R D D
Sbjct: 1143 GHQLSPNISACIDINECELSAHLCPNGRCVNLIGKYQCACNPGYHSTPDRLFCVDIDECS 1202
Query: 485 VDGG------DSGSGEPPPSPTPGSTLTP 507
+ G + G S PG L P
Sbjct: 1203 IMNGGCETFCTNSEGSYECSCQPGFALMP 1231
Score = 76.6 bits (187), Expect = 6e-14
Identities = 76/296 (25%), Positives = 108/296 (36%), Gaps = 102/296 (34%)
Query: 261 GAPRCQCPAGAALQADGRSCTASATQSCNDLCEHFCVPNP---------DQPGSYSCMCE 311
G+ CQC AG T + T+ C D+ E C+ N + GS+ C+C
Sbjct: 509 GSYTCQCRAGY-------QSTLTRTE-CRDIDE--CLQNGRICNNGRCINTDGSFHCVCN 558
Query: 312 TGYRLAADQHRCEDVDDCILE--------------------------------------- 332
G+ + D CED+D+C +
Sbjct: 559 AGFHVTRDGKNCEDMDECSIRNMCLNGMCINEDGSFKCICKPGFQLASDGRYCKDINECE 618
Query: 333 -PSPCPQ-RCVNTQGGFECHCYPNYDL-VDG-------------------ECVEPV---- 366
P C RCVNT G + C C+P + +DG +C++P+
Sbjct: 619 TPGICMNGRCVNTDGSYRCECFPGLAVGLDGRVCVDTHMRSTCYGGYKRGQCIKPLFGAV 678
Query: 367 --DPCFRANCEY----QCQPL---NQTSY--LCVCAEGFAPIPHEPHRCQMFCNQTACPA 415
C A+ EY CQP N Y LC G + + C + + CP
Sbjct: 679 TKSECCCASTEYAFGEPCQPCPAQNSAEYQALCSSGPGMTSAGSDINECAL--DPDICPN 736
Query: 416 DCDPNTQAS--CECPEGYILDD-GFICTDIDECE-NGGFC-SGVCHNLPGTFECIC 466
N + + C C GY +D G C DI+EC N C +G C N PG+F C C
Sbjct: 737 GICENLRGTYKCICNSGYEVDSTGKNCVDINECVLNSLLCDNGQCRNTPGSFVCTC 792
Score = 76.3 bits (186), Expect = 7e-14
Identities = 49/183 (26%), Positives = 66/183 (36%), Gaps = 47/183 (25%)
Query: 224 CTAPPGAVQGHWA--------------------REAPGAWDCSVENG------------- 250
C PPG Q H + + PG++ C + G
Sbjct: 2509 CKCPPGFTQHHTSCIDNNECTSDINLCGSKGICQNTPGSFTCECQRGFSLDQTGSSCEDV 2568
Query: 251 -------GCEHACNAIPGAPRCQCPAGAALQADGRSCTASATQSCNDLCEHFC--VPNPD 301
C+H C I G RC CP G C C L H C +
Sbjct: 2569 DECEGNHRCQHGCQNIIGGYRCSCPQGYLQHYQWNQCVDE--NEC--LSAHICGGASCHN 2624
Query: 302 QPGSYSCMCETGYRLAADQHRCEDVDDCILEPSPCPQRCVNTQGGFECHCYPNYDLV-DG 360
GSY CMC G++ C+D+++C +PC C NT+GG+ C C P Y + G
Sbjct: 2625 TLGSYKCMCPAGFQYEQFSGGCQDINECGSAQAPCSYGCSNTEGGYLCGCPPGYFRIGQG 2684
Query: 361 ECV 363
CV
Sbjct: 2685 HCV 2687
Score = 72.4 bits (176), Expect = 1e-12
Identities = 78/291 (26%), Positives = 106/291 (36%), Gaps = 60/291 (20%)
Query: 224 CTAPPGAVQGHWAREAPGAWDCSVENGGCEHACNAIPGAPRCQCPAGAALQADGRSCTAS 283
C P G + E +CSV N C + G C C G G T
Sbjct: 2151 CECPFGYILA--GNECVDTDECSVGNPCGNGTCKNVIGGFECTCEEGF---EPGPMMTCE 2205
Query: 284 ATQSCND---LCEHFCVPNPDQPGSYSCMCETGYRLAADQHRCEDVDDCILEPSPCPQR- 339
C LC CV + GSY C C GY L D+ C+D D+C C ++
Sbjct: 2206 DINECAQNPLLCAFRCV---NTYGSYECKCPVGYVLREDRRMCKDEDECEEGKHDCTEKQ 2262
Query: 340 --CVNTQGGFECHCYPNYD-LVDGE-CVEPVDPCFRAN-CEYQCQPLNQTSYLCVCAEGF 394
C N G + C C P Y DGE CV+ + + CE + SY C C +GF
Sbjct: 2263 MECKNLIGTYMCICGPGYQRRPDGEGCVDENECQTKPGICENGRCLNTRGSYTCECNDGF 2322
Query: 395 APIPHE----------------PHRCQMFCN------QTACPADCDPNTQASCE------ 426
P++ + CQ+ + ++ C D CE
Sbjct: 2323 TASPNQDECLDNREGYCFTEVLQNMCQIGSSNRNPVTKSECCCDGGRGWGPHCEICPFQG 2382
Query: 427 -------CPEGYILDDGFIC--TDIDECE--NGGFCSGVCHNLPGTFECIC 466
CP G GF+ DIDEC+ + +G C N G++ CIC
Sbjct: 2383 TVAFKKLCPHG----RGFMTNGADIDECKVIHDVCRNGECVNDRGSYHCIC 2429
Score = 70.9 bits (172), Expect = 3e-12
Identities = 60/223 (26%), Positives = 91/223 (40%), Gaps = 13/223 (5%)
Query: 280 CTASATQSCNDLCEHFCVPNPDQPGSYSCMCETGYRLAADQHRCEDVDDCILEPSPCPQR 339
C+ + ++ N CE +P+ D+ + G+ + D+D+C P C
Sbjct: 1721 CSYNIGRAWNKPCEQCPIPSTDEFATLCGSQRPGFVIDIYTGLPVDIDECREIPGVCENG 1780
Query: 340 -CVNTQGGFECHCYPNYDLVDGECV-EPVDPCFRAN-CEYQCQPLNQT-SYLCVCAEGFA 395
C+N G F C C + D V E +D C C+ + +N SY C C G+
Sbjct: 1781 VCINMVGSFRCECPVGFFYNDKLLVCEDIDECQNGPVCQRNAECINTAGSYRCDCKPGYR 1840
Query: 396 PIP----HEPHRCQMFCNQTACPADCDPNTQASCECPEGYIL-DDGFICTDIDECENGGF 450
++ + CQ N + D C C G+ DD +C DI+ECE
Sbjct: 1841 FTSTGQCNDRNECQEIPNICSHGQCIDTVGSFYCLCHTGFKTNDDQTMCLDINECERDAC 1900
Query: 451 CSGVCHNLPGTFECICGPDSALARHIGTDCDSGKVDGGDSGSG 493
+G C N G+F C C L+ + DC VD SG+G
Sbjct: 1901 GNGTCRNTIGSFNCRCNHGFILSHN--NDCID--VDECASGNG 1939
Score = 69.3 bits (168), Expect = 9e-12
Identities = 87/351 (24%), Positives = 113/351 (32%), Gaps = 94/351 (26%)
Query: 223 MCTAPPGAVQGHWAREAPG-------AWDCSVENGGCEHA--CNAIPGAPR--------- 264
+C A G GH P + ++ G C+ C AIPG +
Sbjct: 208 LCCATVGRAWGHPCEMCPAQPHPCRRGFIPNIRTGACQDVDECQAIPGLCQGGNCINTVG 267
Query: 265 ---CQCPAGAALQADGRSCTASATQSCNDLCEHFCVPNPDQPG-------SYSCMCETGY 314
C+CPAG L +Q C D+ E +P + G SY C C G+
Sbjct: 268 SFECKCPAGHKLN--------EVSQKCEDIDECSTIPGICEGGECTNTVSSYFCKCPPGF 319
Query: 315 RLAADQHRCEDVDDCILEPSPCPQRCVN----TQGGFECHC------YPNYDLVDGECVE 364
+ D RC DV + RC N + +C C P + C
Sbjct: 320 YTSPDGTRCIDVRPGYCYTALTNGRCSNQLPQSITKMQCCCDAGRCWSPGVTVAPEMCPI 379
Query: 365 PVDPCFRANC----------EYQCQPLNQTSYLCVCAEGFAPIPH--------------- 399
F C EY PL + GF P P
Sbjct: 380 RATEDFNKLCSVPMVIPGRPEYPPPPLGPIPPVLPVPPGFPPGPQIPVPRPPVEYLYPSR 439
Query: 400 EPHR---------CQM---FCNQTAC---PADCDPNTQASCECPEGYILDDGFICTDIDE 444
EP R CQ+ C C P C CEC +G+ LD C D+DE
Sbjct: 440 EPPRVLPVNVTDYCQLVRYLCQNGRCIPTPGSC------RCECNKGFQLDLRGECIDVDE 493
Query: 445 CENGGFCSGVCHNLPGTFECIC--GPDSALARHIGTDCDSGKVDGGDSGSG 493
CE G C N G++ C C G S L R D D +G +G
Sbjct: 494 CEKNPCAGGECINNQGSYTCQCRAGYQSTLTRTECRDIDECLQNGRICNNG 544
Score = 68.9 bits (167), Expect = 1e-11
Identities = 50/148 (33%), Positives = 65/148 (43%), Gaps = 19/148 (12%)
Query: 339 RCVNTQGGFECHCYPNYDL-VDGECVEPVDPCFRANCEYQCQPLNQTSYLCVCAEGFAPI 397
RC+ T G C C + L + GEC++ VD C + C NQ SY C C G+
Sbjct: 464 RCIPTPGSCRCECNKGFQLDLRGECID-VDECEKNPCAGGECINNQGSYTCQCRAGYQST 522
Query: 398 P-----HEPHRCQM---FCNQTACPADCDPNTQAS--CECPEGY-ILDDGFICTDIDECE 446
+ C CN C NT S C C G+ + DG C D+DEC
Sbjct: 523 LTRTECRDIDECLQNGRICNNGRCI-----NTDGSFHCVCNAGFHVTRDGKNCEDMDECS 577
Query: 447 NGGFC-SGVCHNLPGTFECICGPDSALA 473
C +G+C N G+F+CIC P LA
Sbjct: 578 IRNMCLNGMCINEDGSFKCICKPGFQLA 605
Score = 42.4 bits (98), Expect = 0.001
Identities = 62/234 (26%), Positives = 79/234 (33%), Gaps = 62/234 (26%)
Query: 267 CPAGAALQADGRSCTASATQSCNDLCEHFCV-PNPDQPGSYSCMCETGYRLAADQHRCED 325
CP L + SC D FC PN C C +G A
Sbjct: 68 CPGWKTLPGGNQCIVPICRHSCGD---GFCSRPN-------MCTCPSGQ--IAPSCGSRS 115
Query: 326 VDDCILEPSPCPQRCVNTQGGFECHCYPNYDLVDGECVEPVDPCFRANCEYQCQPLNQTS 385
+ C + RC+N + HC + C +PV CE C LN
Sbjct: 116 IQHCNI-------RCMNGGSCSDDHCLCQKGYIGTHCGQPV-------CESGC--LNGGR 159
Query: 386 YL----CVCAEGF-APIPHEPHR------------CQ-----MFCNQTACPADCDPNTQA 423
+ C C GF P +R CQ + C +T C A
Sbjct: 160 CVAPNRCACTYGFTGPQCERDYRTGPCFTVISNQMCQGQLSGIVCTKTLCCATVGRAWGH 219
Query: 424 SCE-CP-EGYILDDGFI-------CTDIDECEN-GGFC-SGVCHNLPGTFECIC 466
CE CP + + GFI C D+DEC+ G C G C N G+FEC C
Sbjct: 220 PCEMCPAQPHPCRRGFIPNIRTGACQDVDECQAIPGLCQGGNCINTVGSFECKC 273
>gi|56237021 fibrillin 3 precursor [Homo sapiens]
Length = 2809
Score = 121 bits (304), Expect = 2e-27
Identities = 83/238 (34%), Positives = 109/238 (45%), Gaps = 21/238 (8%)
Query: 244 DCSVENGGCEHACNAIPGAPRCQCPAGAALQADGRSCTASATQSCND---LCEHFCVPNP 300
+C V+NGGC+ C G+ RC C G +L DGR+C + C + +C+ N
Sbjct: 1158 ECRVQNGGCDVHCINTEGSYRCSCGQGYSLMPDGRAC--ADVDECEENPRVCDQGHCTN- 1214
Query: 301 DQPGSYSCMCETGYRLAADQHRCEDVDDCILEPSPCPQ-RCVNTQGGFECHCYPNYDLVD 359
PG + C+C G+ D C DVD+C L P C C NT+G F CHC Y +
Sbjct: 1215 -MPGGHRCLCYDGFMATPDMRTCVDVDECDLNPHICLHGDCENTKGSFVCHCQLGYMVRK 1273
Query: 360 GEC-VEPVDPCFRA--NCEYQCQPLN-QTSYLCVCAEGFAPIPHEPH---RCQMFCNQTA 412
G VD C NC+ LN S+ C C G+ E H C ++ +
Sbjct: 1274 GATGCSDVDECEVGGHNCDSHASCLNIPGSFSCRCLPGWVGDGFECHDLDECVSQEHRCS 1333
Query: 413 CPADCDPNTQAS--CECPEGYILDDGFICTDIDEC-ENGGFC-SGVCHNLPGTFECIC 466
DC N S C C +G+ DGF C D DEC EN C +G C N PG + C C
Sbjct: 1334 PRGDC-LNVPGSYRCTCRQGF-AGDGFFCEDRDECAENVDLCDNGQCLNAPGGYRCEC 1389
Score = 116 bits (291), Expect = 5e-26
Identities = 76/231 (32%), Positives = 110/231 (47%), Gaps = 25/231 (10%)
Query: 256 CNAIPGAPRCQCPAGAALQADGRSCTASATQSCND-LCEHF-CVPNPDQPGSYSCMCETG 313
C G+ +CQCP G L A G +C S +D LC H CV + G++ C C G
Sbjct: 1087 CTNTDGSYKCQCPPGHELTAKGTACEDIDECSLSDGLCPHGQCV---NVIGAFQCSCHAG 1143
Query: 314 YRLAADQHRCEDVDDCILEPSPCPQRCVNTQGGFECHCYPNYDLV-DGECVEPVDPCF-- 370
++ D+ C D+++C ++ C C+NT+G + C C Y L+ DG VD C
Sbjct: 1144 FQSTPDRQGCVDINECRVQNGGCDVHCINTEGSYRCSCGQGYSLMPDGRACADVDECEEN 1203
Query: 371 -RANCEYQCQPLNQTSYLCVCAEGFAPIPH-----EPHRCQMFCNQTAC-PADCDPNTQA 423
R + C + + C+C +GF P + C + N C DC+ NT+
Sbjct: 1204 PRVCDQGHCTNM-PGGHRCLCYDGFMATPDMRTCVDVDECDL--NPHICLHGDCE-NTKG 1259
Query: 424 S--CECPEGYILDDGFI-CTDIDECENGGF---CSGVCHNLPGTFECICGP 468
S C C GY++ G C+D+DECE GG C N+PG+F C C P
Sbjct: 1260 SFVCHCQLGYMVRKGATGCSDVDECEVGGHNCDSHASCLNIPGSFSCRCLP 1310
Score = 111 bits (277), Expect = 2e-24
Identities = 90/333 (27%), Positives = 135/333 (40%), Gaps = 49/333 (14%)
Query: 158 CEVKADGFLCEFHFPATCRPLAVEPGAAAAAVSITYGTPFAARGADFQALPVGSSAAVAP 217
C +A GFL + H T +PL ++ A+ + +
Sbjct: 1703 CGNQAPGFLTDIH---TGKPLDIDECGEIPAIC-------------------ANGICINQ 1740
Query: 218 LGLQLMCTAPPGAVQGHWAREAPGAWDCSVENGGCEHA--CNAIPGAPRCQCPAGAALQA 275
+G C P G +C C+ C IPG+ RC+C G L
Sbjct: 1741 IG-SFRCECPAGFNYNSILLACEDVDECGSRESPCQQNADCINIPGSYRCKCTRGYKLSP 1799
Query: 276 DGRSCTASATQSCNDLCEHF-CVPNPDQPGSYSCMCETGYRLAADQHRCEDVDDCILEPS 334
G + + ++C H C+ D GSY C+C G++ +ADQ C D+D+C +
Sbjct: 1800 GGACVGRNECREIPNVCSHGDCM---DTEGSYMCLCHRGFQASADQTLCMDIDEC--DRQ 1854
Query: 335 PCPQ-RCVNTQGGFECHCYPNYDLV-DGECVEPVDPC---FRANCEYQCQPLNQTSYLCV 389
PC C N G + C C+P + + +G+CV+ D C C + S+ C+
Sbjct: 1855 PCGNGTCKNIIGSYNCLCFPGFVVTHNGDCVD-FDECTTLVGQVCRFGHCLNTAGSFHCL 1913
Query: 390 CAEGFAPIPH-----EPHRCQMFCNQTACPADCDPNTQAS--CECPEGYILDDGFICTDI 442
C +GF + + C T P C N + S C CP G+ + C DI
Sbjct: 1914 CQDGFELTADGKNCVDTNECLSLAG-TCLPGTCQ-NLEGSFRCICPPGFQVQSDH-CIDI 1970
Query: 443 DEC-ENGGFC-SGVCHNLPGTFECICGPDSALA 473
DEC E C G C N PG+F+C+C P L+
Sbjct: 1971 DECSEEPNLCLFGTCTNSPGSFQCLCPPGFVLS 2003
Score = 108 bits (270), Expect = 1e-23
Identities = 87/305 (28%), Positives = 120/305 (39%), Gaps = 30/305 (9%)
Query: 182 PGAAAAAVSITYGTPFAARGADFQALPV-----GSSAAVAPLGLQLMCTAPPGAVQGHWA 236
PG +A +G+ + A G D + + LG C G A
Sbjct: 2342 PGTSAYRKLCPHGSGYTAEGRDVDECRMLAHLCAHGECINSLG-SFRCHCQAGYTPDATA 2400
Query: 237 REAPGAWDCSVENGGCEHACNAIPGAPRCQCPAGAALQADGRSC-TASATQSCNDLCEHF 295
+CS C C G+ C CP G L+ DGR+C S C+
Sbjct: 2401 TTCLDMDECSQVPKPCTFLCKNTKGSFLCSCPRGYLLEEDGRTCKDLDECTSRQHNCQFL 2460
Query: 296 CVPNPDQPGSYSCMCETGYRLAADQHRCEDVDDCILEPSPCPQ--RCVNTQGGFECHCYP 353
CV + G+++C C G+ C D D+C +P PC C NT G F C C+
Sbjct: 2461 CV---NTVGAFTCRCPPGF--TQHHQACFDNDECSAQPGPCGAHGHCHNTPGSFRCECHQ 2515
Query: 354 NYDLV-DGECVEPVDPCFRAN-CEYQCQPLNQT-SYLCVCAEGFAPIPH-----EPHRCQ 405
+ LV G E V+ C + C++ CQ NQ Y C C +GF + + C
Sbjct: 2516 GFTLVSSGHGCEDVNECDGPHRCQHGCQ--NQLGGYRCSCPQGFTQHSQWAQCVDENECA 2573
Query: 406 MFCNQTACPADCDPNTQAS--CECPEGYILDDGF-ICTDIDECE-NGGFCSGVCHNLPGT 461
+ + C + NT C CP G+ D C ++DEC G CS C N PG
Sbjct: 2574 L--SPPTCGSASCRNTLGGFRCVCPSGFDFDQALGGCQEVDECAGRRGPCSYSCANTPGG 2631
Query: 462 FECIC 466
F C C
Sbjct: 2632 FLCGC 2636
Score = 95.5 bits (236), Expect = 1e-19
Identities = 71/234 (30%), Positives = 98/234 (41%), Gaps = 64/234 (27%)
Query: 291 LCEHFCVPNPDQPGSYSCMCETGYRLAADQHRCEDVDDCILEPSPCPQ-RCVNTQGGFEC 349
LC H N GS+ C C G+ L A + C D+D+C + P C Q CVNT G FEC
Sbjct: 996 LCTHGTCRNT--VGSFHCACAGGFALDAQERNCTDIDECRISPDLCGQGTCVNTPGSFEC 1053
Query: 350 HCYPNYD---LVDGECVEPVDPCFR------------ANCEYQCQ--------------- 379
C+P Y+ ++ C++ VD C R + Y+CQ
Sbjct: 1054 ECFPGYESGFMLMKNCMD-VDECARDPLLCRGGTCTNTDGSYKCQCPPGHELTAKGTACE 1112
Query: 380 ------------PLNQT-----SYLCVCAEGFAPIPH-----EPHRCQMFCNQTACPADC 417
P Q ++ C C GF P + + C++ C C
Sbjct: 1113 DIDECSLSDGLCPHGQCVNVIGAFQCSCHAGFQSTPDRQGCVDINECRV--QNGGCDVHC 1170
Query: 418 DPNTQAS--CECPEGY-ILDDGFICTDIDEC-ENGGFC-SGVCHNLPGTFECIC 466
NT+ S C C +GY ++ DG C D+DEC EN C G C N+PG C+C
Sbjct: 1171 -INTEGSYRCSCGQGYSLMPDGRACADVDECEENPRVCDQGHCTNMPGGHRCLC 1223
Score = 93.6 bits (231), Expect = 4e-19
Identities = 69/208 (33%), Positives = 88/208 (42%), Gaps = 33/208 (15%)
Query: 281 TASATQSCNDLCEHF--------CVPNPDQPGSYSCMCETGYRLAADQHRCEDVDDCILE 332
TA+ Q+ D+C HF C+P P SY C C GY + C DVD+C
Sbjct: 402 TATLNQTI-DICRHFTNLCLNGRCLPTPS---SYRCECNVGYTQDV-RGECIDVDEC--T 454
Query: 333 PSPCPQ-RCVNTQGGFECHCYPNYDLVDGE--CVEPVDPCFRAN--CEYQCQPLNQTSYL 387
SPC CVN G + C CYP + CV+ VD C + C + S+
Sbjct: 455 SSPCHHGDCVNIPGTYHCRCYPGFQATPTRQACVD-VDECIVSGGLCHLGRCVNTEGSFQ 513
Query: 388 CVCAEGFAPIP-------HEPHRCQMFCNQTACPADCDPNTQASCECPEGYIL-DDGFIC 439
CVC GF P H C C + + SC C G++L G C
Sbjct: 514 CVCNAGFELSPDGKNCVDHNECATSTMCVNGVC---LNEDGSFSCLCKPGFLLAPGGHYC 570
Query: 440 TDIDECENGGFC-SGVCHNLPGTFECIC 466
DIDEC+ G C +G C N G+F C C
Sbjct: 571 MDIDECQTPGICVNGHCTNTEGSFRCQC 598
Score = 93.2 bits (230), Expect = 6e-19
Identities = 87/296 (29%), Positives = 109/296 (36%), Gaps = 62/296 (20%)
Query: 224 CTAPPG-AVQGHWAREAPGAWDCSVENGGCEHA-CNAIPGAPRCQCPAGAALQADGRSCT 281
C PPG VQ + +CS E C C PG+ +C CP G L +G C
Sbjct: 1954 CICPPGFQVQSDHCIDID---ECSEEPNLCLFGTCTNSPGSFQCLCPPGFVLSDNGHRCF 2010
Query: 282 ASATQSCNDLCEH----------------FCVPNPDQPGSYSCMCETGYRLAADQHRC-- 323
+ C E C P + C AA Q C
Sbjct: 2011 DTRQSFCFTRFEAGKCSVPKAFNTTKTRCCCSKRPGEGWGDPCELCPQEGSAAFQELCPF 2070
Query: 324 ------------EDVDDCILEPSPCPQR-CVNTQGGFECHCYPNYDL-------VDGECV 363
EDV++C P C CVNT G F C C Y L VD +
Sbjct: 2071 GHGAVPGPDDSREDVNECAENPGVCTNGVCVNTDGSFRCECPFGYSLDFTGINCVDTDEC 2130
Query: 364 EPVDPCFRANCEYQCQPLNQTSYLCVCAEGFAP----IPHEPHRCQMFCNQTACPADCDP 419
PC + C + C CA+GF P + C + N C C
Sbjct: 2131 SVGHPCGQGTCTNVIG-----GFECACADGFEPGLMMTCEDIDECSL--NPLLCAFRCH- 2182
Query: 420 NTQAS--CECPEGYIL-DDGFICTDIDECENGG---FCSGV-CHNLPGTFECICGP 468
NT+ S C CP GY L +DG +C D+DEC +G G+ C NL GTF C+C P
Sbjct: 2183 NTEGSYLCTCPAGYTLREDGAMCRDVDECADGQQDCHARGMECKNLIGTFACVCPP 2238
Score = 92.8 bits (229), Expect = 8e-19
Identities = 81/297 (27%), Positives = 113/297 (38%), Gaps = 54/297 (18%)
Query: 229 GAVQ-GHWAREAPGAWD-----CSVENGGCEHACNAIPGAPRCQ----CPAGAALQADGR 278
GA++ G AR PG C+ + G C P + C +G + DGR
Sbjct: 622 GAIEKGSCARPFPGTVTKSECCCANPDHGFGEPCQLCPAKDSAEFQALCSSGLGITTDGR 681
Query: 279 S---CTASATQSCNDLCEHFCVPNPDQPGSYSCMCETGYRLAADQHRCEDVDDCILEPSP 335
C N +CE+ GSY C+C GY A C DVD+C L
Sbjct: 682 DINECALDPEVCANGVCENL-------RGSYRCVCNLGYEAGASGKDCTDVDECALNSLL 734
Query: 336 CPQR-CVNTQGGFECHCYPNYDL-VDGECVEPVDPCFRANC-EYQCQPLNQTSYLCVCAE 392
C C N+ G + C C P + D E + VD C + C C+ L SY C C
Sbjct: 735 CDNGWCQNSPGSYSCSCPPGFHFWQDTEICKDVDECLSSPCVSGVCRNL-AGSYTCKCGP 793
Query: 393 GFAPIPH----------------EPHRCQMFCNQTACPADCDPNTQAS-------CE--- 426
G P + RC++ + ++C A+ CE
Sbjct: 794 GSRLDPSGTFCLDSTKGTCWLKIQESRCEVNLQGASLRSECCATLGAAWGSPCERCEIDP 853
Query: 427 -CPEGYILDDGFICTDIDECEN-GGFC-SGVCHNLPGTFECICGPDSALARHIGTDC 480
C G+ G C D++ECE+ G C +G C N G+F C C P+ + G C
Sbjct: 854 ACARGFARMTGVTCDDVNECESFPGVCPNGRCVNTAGSFRCEC-PEGLMLDASGRLC 909
Score = 86.7 bits (213), Expect = 5e-17
Identities = 71/228 (31%), Positives = 96/228 (42%), Gaps = 26/228 (11%)
Query: 221 QLMCTAPPGAVQG-HWAREAPGAWDCSVENGGCEHA-CNAIPGAPRCQCPAGAALQADGR 278
Q +C GAV G +RE +C+ G C + C G+ RC+CP G +L G
Sbjct: 2065 QELCPFGHGAVPGPDDSREDVN--ECAENPGVCTNGVCVNTDGSFRCECPFGYSLDFTGI 2122
Query: 279 SCTASATQSCNDLCEHFCVPNPDQPGSYSCMCETGYRLAADQHRCEDVDDCILEPSPCPQ 338
+C + S C N G + C C G+ CED+D+C L P C
Sbjct: 2123 NCVDTDECSVGHPCGQGTCTNVI--GGFECACADGFEPGL-MMTCEDIDECSLNPLLCAF 2179
Query: 339 RCVNTQGGFECHCYPNYDL-VDGECVEPVDPCF--RANCE---YQCQPLNQTSYLCVCAE 392
RC NT+G + C C Y L DG VD C + +C +C+ L T + CVC
Sbjct: 2180 RCHNTEGSYLCTCPAGYTLREDGAMCRDVDECADGQQDCHARGMECKNLIGT-FACVCPP 2238
Query: 393 GFAPIPHEPHRCQMFCNQTACPADCD-------PNTQAS--CECPEGY 431
G P+P C + C A D NT S C+C EG+
Sbjct: 2239 GMRPLPGSGEGC---TDDNECHAQPDLCVNGRCVNTAGSFRCDCDEGF 2283
Score = 85.5 bits (210), Expect = 1e-16
Identities = 82/297 (27%), Positives = 109/297 (36%), Gaps = 78/297 (26%)
Query: 224 CTAPPG---AVQGHWAREAPGAWDCSVENGGCEHACNAIPGAPRCQCPAGAALQADGRSC 280
C PG A GH+ + +C C G+ RCQC G A+ DGR C
Sbjct: 555 CLCKPGFLLAPGGHYCMDID---ECQTPGICVNGHCTNTEGSFRCQCLGGLAVGTDGRVC 611
Query: 281 TASATQS-CNDLCE---------------HFCVPNPDQ-------------PGSYSCMCE 311
+ +S C E C NPD + +C
Sbjct: 612 VDTHVRSTCYGAIEKGSCARPFPGTVTKSECCCANPDHGFGEPCQLCPAKDSAEFQALCS 671
Query: 312 TGYRLAADQHRCEDVDDCILEPSPCPQR-CVNTQGGFECHCYPNYDL-VDGECVEPVDPC 369
+G + D D+++C L+P C C N +G + C C Y+ G+ VD C
Sbjct: 672 SGLGITTDGR---DINECALDPEVCANGVCENLRGSYRCVCNLGYEAGASGKDCTDVDEC 728
Query: 370 FRANCEYQCQPLNQTSYLCVCAEGFAPIPHEPHRCQMFCNQTACPADCDPNTQASCECPE 429
LN +C G+ CQ P + SC CP
Sbjct: 729 ----------ALNSL----LCDNGW---------CQN-----------SPGSY-SCSCPP 753
Query: 430 GY-ILDDGFICTDIDECENGGFCSGVCHNLPGTFECICGPDSALARHIGTDC-DSGK 484
G+ D IC D+DEC + SGVC NL G++ C CGP S L GT C DS K
Sbjct: 754 GFHFWQDTEICKDVDECLSSPCVSGVCRNLAGSYTCKCGPGSRLDPS-GTFCLDSTK 809
Score = 84.3 bits (207), Expect = 3e-16
Identities = 82/284 (28%), Positives = 104/284 (36%), Gaps = 38/284 (13%)
Query: 216 APLGLQLMCTAPPGAVQGHWAREAPGAWDCSVENGGCEHACNAIPGAPRCQCPAGAALQA 275
AP G + C + H R +C+ N +C +PG RC C G L
Sbjct: 1381 APGGYRCECEMGFDPTEDH--RACQDVDECAQGNLCAFGSCENLPGMFRCICNGGYELDR 1438
Query: 276 DGRSCT-----ASATQSCNDLCEHFCVPNPDQPGSYSCMCETGYRLAADQHRCED--VDD 328
G +CT A N +C + PGSY C C + L C D +
Sbjct: 1439 GGGNCTDINECADPVNCINGVC-------INTPGSYLCSCPQDFELNPSGVGCVDTRAGN 1491
Query: 329 CILEPSPCPQRCVNTQGGFECHCYPNYDLVDGECVEPVDPCFRANCEYQCQPLNQTSY-- 386
C LE G C + C + + CE C N T Y
Sbjct: 1492 CFLETHD------RGDSGISCSAEIGVGVTRASCCCSLGRAWGNPCEL-CPMANTTEYRT 1544
Query: 387 LCVCAEGFAP-----IPHEPHRCQMFCNQTACPADCDPNTQAS--CECPEGYILDDGF-I 438
LC EGF P I + CQ C NT S CECP GY L + I
Sbjct: 1545 LCPGGEGFQPNRITVILEDIDECQEL--PGLCQGGDCVNTFGSFQCECPPGYHLSEHTRI 1602
Query: 439 CTDIDECE-NGGFCS-GVCHNLPGTFECICGPDSALARHIGTDC 480
C DIDEC + G C G C+N G + C+C P L + G +C
Sbjct: 1603 CEDIDECSTHSGICGPGTCYNTLGNYTCVC-PAEYLQVNGGNNC 1645
Score = 84.0 bits (206), Expect = 4e-16
Identities = 88/293 (30%), Positives = 110/293 (37%), Gaps = 66/293 (22%)
Query: 256 CNAIPGAPRCQCPAGAALQADGRSCTASATQSCN-DLCEHFCVPNPDQPGSYSCMCETGY 314
C +PG+ RC C G A DG C + N DLC++ N PG Y C CE G+
Sbjct: 1338 CLNVPGSYRCTCRQGFA--GDGFFCEDRDECAENVDLCDNGQCLNA--PGGYRCECEMGF 1393
Query: 315 RLAADQHRCEDVDDCILEPSPCPQRCVNTQGGFECHCYPNYDLVDG--------ECVEPV 366
D C+DVD+C C N G F C C Y+L G EC +PV
Sbjct: 1394 DPTEDHRACQDVDECAQGNLCAFGSCENLPGMFRCICNGGYELDRGGGNCTDINECADPV 1453
Query: 367 DPCFRANCEYQCQPLNQT-SYLCVCAEGFAPIPH-------EPHRCQMFCNQ-----TAC 413
+ C C +N SYLC C + F P C + + +C
Sbjct: 1454 N-CINGVC------INTPGSYLCSCPQDFELNPSGVGCVDTRAGNCFLETHDRGDSGISC 1506
Query: 414 PADCDPN-TQASCECPEGYIL---------------------DDGF-------ICTDIDE 444
A+ T+ASC C G +GF I DIDE
Sbjct: 1507 SAEIGVGVTRASCCCSLGRAWGNPCELCPMANTTEYRTLCPGGEGFQPNRITVILEDIDE 1566
Query: 445 C-ENGGFC-SGVCHNLPGTFECICGPDSALARH--IGTDCDSGKVDGGDSGSG 493
C E G C G C N G+F+C C P L+ H I D D G G G
Sbjct: 1567 CQELPGLCQGGDCVNTFGSFQCECPPGYHLSEHTRICEDIDECSTHSGICGPG 1619
Score = 77.8 bits (190), Expect = 3e-14
Identities = 70/228 (30%), Positives = 84/228 (36%), Gaps = 37/228 (16%)
Query: 256 CNAIPGAPRCQCPAGAALQADGRSCTASATQSCNDLCEHFCVPN-------PDQPGSYSC 308
C + G+ RC CP G +Q+D C D+ E PN + PGS+ C
Sbjct: 1945 CQNLEGSFRCICPPGFQVQSD----------HCIDIDECSEEPNLCLFGTCTNSPGSFQC 1994
Query: 309 MCETGYRLAADQHRCEDVDDCI----LEPSPCPQRCVNTQGGFECHCYPNYDLVDGECVE 364
+C G+ L+ + HRC D E C C C G
Sbjct: 1995 LCPPGFVLSDNGHRCFDTRQSFCFTRFEAGKCSVPKAFNTTKTRCCCSKRPGEGWG---- 2050
Query: 365 PVDPCFRANCEYQCQPLNQTSYLCVCAEGFAPIPHEPHRCQMFC--NQTACPADCDPNTQ 422
DPC C + Q LC G P P + C N C NT
Sbjct: 2051 --DPC--ELCPQEGSAAFQE--LCPFGHGAVPGPDDSREDVNECAENPGVCTNGVCVNTD 2104
Query: 423 AS--CECPEGYILD-DGFICTDIDECENGGFC-SGVCHNLPGTFECIC 466
S CECP GY LD G C D DEC G C G C N+ G FEC C
Sbjct: 2105 GSFRCECPFGYSLDFTGINCVDTDECSVGHPCGQGTCTNVIGGFECAC 2152
Score = 73.2 bits (178), Expect = 6e-13
Identities = 80/308 (25%), Positives = 111/308 (36%), Gaps = 63/308 (20%)
Query: 252 CEHA-CNAIPGAPRCQCPAGAALQADGRSCTASATQSC---NDLCEHFCVPNPDQPGSYS 307
C H C IPG C+C G ++C C LC N + GS+
Sbjct: 458 CHHGDCVNIPGTYHCRCYPGFQATPTRQACVD--VDECIVSGGLCHLGRCVNTE--GSFQ 513
Query: 308 CMCETGYRLAADQHRCEDVDDCILEPSPCPQRCVNTQGGFECHCYPNYDLVDG------- 360
C+C G+ L+ D C D ++C C+N G F C C P + L G
Sbjct: 514 CVCNAGFELSPDGKNCVDHNECATSTMCVNGVCLNEDGSFSCLCKPGFLLAPGGHYCMDI 573
Query: 361 -ECVEPVDPCFRANC-----EYQCQPLNQTSY-----LCV----------------CAEG 393
EC P C +C ++CQ L + +CV CA
Sbjct: 574 DECQTP-GICVNGHCTNTEGSFRCQCLGGLAVGTDGRVCVDTHVRSTCYGAIEKGSCAR- 631
Query: 394 FAPIPHEPHRCQMFCNQ---------TACPADCDPNTQASCECPEGYILDDGFICTDIDE 444
P P + + C CPA QA C G I DG DI+E
Sbjct: 632 --PFPGTVTKSECCCANPDHGFGEPCQLCPAKDSAEFQALCSSGLG-ITTDG---RDINE 685
Query: 445 C--ENGGFCSGVCHNLPGTFECIC--GPDSALARHIGTDCDSGKVDGGDSGSGEPPPSPT 500
C + +GVC NL G++ C+C G ++ + TD D ++ +G SP
Sbjct: 686 CALDPEVCANGVCENLRGSYRCVCNLGYEAGASGKDCTDVDECALNSLLCDNGWCQNSPG 745
Query: 501 PGSTLTPP 508
S PP
Sbjct: 746 SYSCSCPP 753
Score = 72.8 bits (177), Expect = 8e-13
Identities = 81/305 (26%), Positives = 115/305 (37%), Gaps = 72/305 (23%)
Query: 244 DCSVENGGCEHA-CNAIPGAPRCQCPAGAALQADGRSCTASATQSC-------------- 288
+C G C + C G+ RC+CP G L A GR C + C
Sbjct: 872 ECESFPGVCPNGRCVNTAGSFRCECPEGLMLDASGRLCVDVRLEPCFLRWDEDECGVTLP 931
Query: 289 ----NDLC----------EHFCVPNPDQPGSYSCMCETGYRLAADQHRC-----EDVDDC 329
D+C E P+P+ ++ +C G A+ +DV++C
Sbjct: 932 GKYRMDVCCCSIGAVWGVECEACPDPESL-EFASLCPRGLGFASRDFLSGRPFYKDVNEC 990
Query: 330 ILEPSPCPQ-RCVNTQGGFECHCYPNYDL---------VDGECVEPVDPCFRANC----- 374
+ P C C NT G F C C + L +D EC D C + C
Sbjct: 991 KVFPGLCTHGTCRNTVGSFHCACAGGFALDAQERNCTDID-ECRISPDLCGQGTCVNTPG 1049
Query: 375 --EYQCQPLNQTSYLCV--CAEGFAPIPHEPHRCQMFCNQTACPADCDPNTQAS--CECP 428
E +C P ++ ++ + C + E R + C C NT S C+CP
Sbjct: 1050 SFECECFPGYESGFMLMKNCMD-----VDECARDPLLCRGGTC-----TNTDGSYKCQCP 1099
Query: 429 EGYILD-DGFICTDIDECE-NGGFC-SGVCHNLPGTFECIC--GPDSALARHIGTDCDSG 483
G+ L G C DIDEC + G C G C N+ G F+C C G S R D +
Sbjct: 1100 PGHELTAKGTACEDIDECSLSDGLCPHGQCVNVIGAFQCSCHAGFQSTPDRQGCVDINEC 1159
Query: 484 KVDGG 488
+V G
Sbjct: 1160 RVQNG 1164
Score = 68.2 bits (165), Expect = 2e-11
Identities = 85/324 (26%), Positives = 117/324 (36%), Gaps = 68/324 (20%)
Query: 223 MCTAPPGAV---QGHWARE----APGAWDCSVENGGCEHACNAIPGAPRCQCPAGAA-LQ 274
+CT P G G R+ A G DC C++ + G C CP G L
Sbjct: 2189 LCTCPAGYTLREDGAMCRDVDECADGQQDCHARGMECKN----LIGTFACVCPPGMRPLP 2244
Query: 275 ADGRSCTASATQSCN---DLCEHF-CVPNPDQPGSYSCMCETGYRLAADQHRCEDVDD-- 328
G CT C+ DLC + CV + GS+ C C+ G++ + C D+
Sbjct: 2245 GSGEGCTDD--NECHAQPDLCVNGRCV---NTAGSFRCDCDEGFQPSPTLTECHDIRQGP 2299
Query: 329 CILEPSPCPQRCVNTQGGF----ECHCY------PNYDLVDGECVEPVDPCFRANCEY-- 376
C E R +++ EC C P +L C P +R C +
Sbjct: 2300 CFAEVLQTMCRSLSSSSEAVTRAECCCGGGRGWGPRCEL----CPLPGTSAYRKLCPHGS 2355
Query: 377 ----------QCQPLNQT-----------SYLCVCAEGFAPIPHEPHRCQMF-CNQTACP 414
+C+ L S+ C C G+ P M C+Q P
Sbjct: 2356 GYTAEGRDVDECRMLAHLCAHGECINSLGSFRCHCQAGYTPDATATTCLDMDECSQVPKP 2415
Query: 415 AD--CDPNTQAS--CECPEGYILD-DGFICTDIDECENGGF-CSGVCHNLPGTFECICGP 468
C NT+ S C CP GY+L+ DG C D+DEC + C +C N G F C C P
Sbjct: 2416 CTFLCK-NTKGSFLCSCPRGYLLEEDGRTCKDLDECTSRQHNCQFLCVNTVGAFTCRCPP 2474
Query: 469 DSALARHIGTDCDSGKVDGGDSGS 492
D D G G+
Sbjct: 2475 GFTQHHQACFDNDECSAQPGPCGA 2498
Score = 67.4 bits (163), Expect = 3e-11
Identities = 54/220 (24%), Positives = 72/220 (32%), Gaps = 65/220 (29%)
Query: 224 CTAPPGAVQGHW-AREAPGAWDCSVENG--------------------GCEHACNAIPGA 262
C+A PG H PG++ C G C+H C G
Sbjct: 2489 CSAQPGPCGAHGHCHNTPGSFRCECHQGFTLVSSGHGCEDVNECDGPHRCQHGCQNQLGG 2548
Query: 263 PRCQCPAGAALQADGRSCTASATQSCNDLCEHFCVPNPDQPGSYSC---------MCETG 313
RC CP G + C E+ C +P GS SC +C +G
Sbjct: 2549 YRCSCPQGFTQHSQWAQCVD----------ENECALSPPTCGSASCRNTLGGFRCVCPSG 2598
Query: 314 YRLAADQHRCEDVDDCILEPSPCPQRCVNTQGGFECHCYPNYDLVDGECVEPVDPCFRAN 373
+ C++VD+C PC C NT GGF C C Y FRA
Sbjct: 2599 FDFDQALGGCQEVDECAGRRGPCSYSCANTPGGFLCGCPQGY--------------FRAG 2644
Query: 374 CEYQCQPLNQTSYLCVCAEGFAPIPHEPHRCQMFCNQTAC 413
+ CV GF+P P + + + AC
Sbjct: 2645 QGH-----------CVSGLGFSPGPQDTPDKEELLSSEAC 2673
Score = 51.2 bits (121), Expect = 3e-06
Identities = 70/243 (28%), Positives = 86/243 (35%), Gaps = 54/243 (22%)
Query: 237 REAPGAWDCSVENGGCEHACNAIPGAPRCQCPAGAALQADGR---SCTASATQSCNDLCE 293
R PG C V C AC G C P ADG SC S C+ C
Sbjct: 73 RTFPGRSQCVVPI--CRRAC----GEGFCSQP-NLCTCADGTLAPSCGVSRGSGCSVSCM 125
Query: 294 HFCVPNPDQPGSYSCMCETGYRLAAD-----QHRCEDVDDCILEPSPCPQRCVNTQGGFE 348
N SC+C+ GY C + CI P RC G
Sbjct: 126 -----NGGTCRGASCLCQKGYTGTVCGQPICDRGCHNGGRCI-----GPNRCACVYGFMG 175
Query: 349 CHCYPNYDLVDGECVEPVDPCFRANCEYQCQPLNQTSYLCVCAEGFA-PIPHEPHRCQMF 407
C +Y G C V P C++Q L T LC G A +P C++
Sbjct: 176 PQCERDYRT--GPCFGQVGP---EGCQHQLTGLVCTKALCCATVGRAWGLP-----CEL- 224
Query: 408 CNQTACPADCDPNTQASCECPEGYI--LDDGFICTDIDECEN-GGFCSG-VCHNLPGTFE 463
CPA P C G+I + G C D+DEC+ G C G C N+ G+F
Sbjct: 225 -----CPAQPHP-------CRRGFIPNIHTG-ACQDVDECQAVPGLCQGGSCVNMVGSFH 271
Query: 464 CIC 466
C C
Sbjct: 272 CRC 274
Score = 51.2 bits (121), Expect = 3e-06
Identities = 68/281 (24%), Positives = 90/281 (32%), Gaps = 68/281 (24%)
Query: 244 DCSVENGGCEH-ACNAIPGAPRCQCPAGAALQADGRSCTASATQSC-NDLCEHFCVPNPD 301
+C G C+ +C + G+ C+CP G L +C +C + L C D
Sbjct: 250 ECQAVPGLCQGGSCVNMVGSFHCRCPVGHRLSDSSAACEDYRAGACFSVLFGGRCAG--D 307
Query: 302 QPGSYS---CMCETGYRLAADQHRCEDVDDCILEPSPCPQRCVNTQGGFECHCYPNYDLV 358
G Y+ C C+ G AA P CP R N F+ C L+
Sbjct: 308 LAGHYTRRQCCCDRGRCWAAGP-----------VPELCPPRGSNE---FQQLCAQRLPLL 353
Query: 359 DGE--------------CVEPVDPCFR---------------ANCEYQCQPLNQTSYLCV 389
G P+ P N LNQT +C
Sbjct: 354 PGHPGLFPGLLGFGSNGMGPPLGPARLNPHGSDARGIPSLGPGNSNIGTATLNQTIDIC- 412
Query: 390 CAEGFAPIPHEPHRCQMFCNQTACPADCDPNTQASCECPEGYILDDGFICTDIDECENGG 449
H + N P + CEC GY D C D+DEC +
Sbjct: 413 -----------RHFTNLCLNGRCLPTP----SSYRCECNVGYTQDVRGECIDVDECTSSP 457
Query: 450 FCSGVCHNLPGTFECICGP--DSALARHIGTDCDSGKVDGG 488
G C N+PGT+ C C P + R D D V GG
Sbjct: 458 CHHGDCVNIPGTYHCRCYPGFQATPTRQACVDVDECIVSGG 498
Score = 45.8 bits (107), Expect = 1e-04
Identities = 52/239 (21%), Positives = 84/239 (35%), Gaps = 29/239 (12%)
Query: 244 DCSVENGGCEHA-CNAIPGAPRCQCPAGAALQADGRSCTASATQSCNDLCEHFCVPNP-- 300
+C G C+ C G+ +C+CP G L R C + ++ H + P
Sbjct: 1566 ECQELPGLCQGGDCVNTFGSFQCECPPGYHLSEHTRIC-----EDIDECSTHSGICGPGT 1620
Query: 301 --DQPGSYSCMCETGYRLAADQHRCEDVDDCIL---EPSPCPQRCVNTQGGFECHCYPN- 354
+ G+Y+C+C Y + C D+ + C C C N
Sbjct: 1621 CYNTLGNYTCVCPAEYLQVNGGNNCMDMRKSVCFRHYNGTCQNELAFNVTRKMCCCSYNI 1680
Query: 355 ---YDLVDGECVEPVDPCFRANCEYQCQPLNQTSYLCVCAEGFAPIPHEPHRCQMFCNQT 411
++ C P+ P ++ C Q +L G E C
Sbjct: 1681 GQAWNRPCEACPTPISPDYQILCGNQA-----PGFLTDIHTGKPLDIDECGEIPAICANG 1735
Query: 412 ACPADCDPNTQASCECPEGYILDDGFI-CTDIDEC---ENGGFCSGVCHNLPGTFECIC 466
C + CECP G+ + + C D+DEC E+ + C N+PG++ C C
Sbjct: 1736 IC---INQIGSFRCECPAGFNYNSILLACEDVDECGSRESPCQQNADCINIPGSYRCKC 1791
Score = 37.0 bits (84), Expect = 0.049
Identities = 31/98 (31%), Positives = 38/98 (38%), Gaps = 14/98 (14%)
Query: 268 PAGAALQADGRSCT-----ASATQSCNDLCEHFCVPNPDQPGSYSCMCETGYRLAADQHR 322
P G Q G CT A+ ++ CE C P QP C G+
Sbjct: 193 PEGCQHQLTGLVCTKALCCATVGRAWGLPCE-LC---PAQPHP----CRRGFIPNIHTGA 244
Query: 323 CEDVDDCILEPSPCPQ-RCVNTQGGFECHCYPNYDLVD 359
C+DVD+C P C CVN G F C C + L D
Sbjct: 245 CQDVDECQAVPGLCQGGSCVNMVGSFHCRCPVGHRLSD 282
Score = 30.4 bits (67), Expect = 4.6
Identities = 17/48 (35%), Positives = 22/48 (45%), Gaps = 7/48 (14%)
Query: 285 TQSCNDLCEHFCVPNPDQPGS-------YSCMCETGYRLAADQHRCED 325
T +C D+ E VP Q GS + C C G+RL+ CED
Sbjct: 242 TGACQDVDECQAVPGLCQGGSCVNMVGSFHCRCPVGHRLSDSSAACED 289
>gi|118572606 hemicentin 1 [Homo sapiens]
Length = 5635
Score = 120 bits (302), Expect = 3e-27
Identities = 84/246 (34%), Positives = 117/246 (47%), Gaps = 25/246 (10%)
Query: 244 DCSVENGGCEHACNAIPGAPRCQCPAGAALQADGRSCTASATQSCNDLCEHFCVPNPDQP 303
+C+ N C H+C+ G C CP G + ADGR+C C L H C D
Sbjct: 5110 ECAAGNP-CSHSCHNAMGTYYCSCPKGLTIAADGRTC--QDIDECA-LGRHTCHAGQDCD 5165
Query: 304 ---GSYSCM--CETGYRLAADQHRCEDVDDCILEPSPCPQRCVNTQGGFECHCYPNYDLV 358
GSY C+ C +G+R +D C+D+++C E SPC QRC N G F C C P Y L
Sbjct: 5166 NTIGSYRCVVRCGSGFRRTSDGLSCQDINEC-QESSPCHQRCFNAIGSFHCGCEPGYQLK 5224
Query: 359 DGECVEPVDPCFRANC--EYQCQPLNQTSYLCV--CAEGFAPIPH----EPHRCQMFCNQ 410
+C++ V+ C + C + C+ + Y C+ C G + + C+ +Q
Sbjct: 5225 GRKCMD-VNECRQNVCRPDQHCKN-TRGGYKCIDLCPNGMTKAENGTCIDIDECKDGTHQ 5282
Query: 411 TACPADCDPNTQAS--CECPEGYILDD-GFICTDIDECEN-GGFCSGVCHNLPGTFECIC 466
C+ NT+ S C CP GY G C DI+ECE C+ C N PG+F+CIC
Sbjct: 5283 CRYNQICE-NTRGSYRCVCPRGYRSQGVGRPCMDINECEQVPKPCAHQCSNTPGSFKCIC 5341
Query: 467 GPDSAL 472
P L
Sbjct: 5342 PPGQHL 5347
Score = 89.4 bits (220), Expect = 8e-18
Identities = 69/244 (28%), Positives = 98/244 (40%), Gaps = 37/244 (15%)
Query: 256 CNAIPGAPRC--QCPAGAALQADGRSCT-----ASATQSC--NDLCEHFCVPNPDQPGSY 306
C G +C CP G +A+ +C T C N +CE+ GSY
Sbjct: 5245 CKNTRGGYKCIDLCPNGMT-KAENGTCIDIDECKDGTHQCRYNQICEN-------TRGSY 5296
Query: 307 SCMCETGYRLAADQHRCEDVDDCILEPSPCPQRCVNTQGGFECHCYPNYDLV-DGECVEP 365
C+C GYR C D+++C P PC +C NT G F+C C P L+ DG+
Sbjct: 5297 RCVCPRGYRSQGVGRPCMDINECEQVPKPCAHQCSNTPGSFKCICPPGQHLLGDGKSCAG 5356
Query: 366 VDPCFRANCEYQCQPLNQTSYLCVCAEGFAPIPHEPHRCQMFCNQTACPADCDPNTQASC 425
++ +Y L + S + + P H ++ + + N++ S
Sbjct: 5357 LERLPNYGTQYSSYNLARFSPV---RNNYQPQQHYRQYSHLYSSYSEY-----RNSRTSL 5408
Query: 426 E---------CPEGYILDDGFICTDIDECENGGFCSGVCHNLPGTFECICGPDSALARHI 476
CPEG C DIDECEN C C N G+++CIC P L H
Sbjct: 5409 SRTRRTIRKTCPEGSEASHD-TCVDIDECENTDACQHECKNTFGSYQCICPPGYQLT-HN 5466
Query: 477 GTDC 480
G C
Sbjct: 5467 GKTC 5470
Score = 62.8 bits (151), Expect = 8e-10
Identities = 38/112 (33%), Positives = 55/112 (49%), Gaps = 12/112 (10%)
Query: 264 RCQCPAGAALQADGRSCTASATQSCNDLCEHFCVPNPDQPGSYSCMCETGYRLAADQHRC 323
R CP G+ D +C D C+H C + GSY C+C GY+L + C
Sbjct: 5416 RKTCPEGSEASHD--TCVDIDECENTDACQHEC---KNTFGSYQCICPPGYQLTHNGKTC 5470
Query: 324 EDVDDCILEPSPC-PQR-CVNTQGGFEC---HCYPNY--DLVDGECVEPVDP 368
+D+D+C+ + C P R C N +G ++C C PNY D V G C++ P
Sbjct: 5471 QDIDECLEQNVHCGPNRMCFNMRGSYQCIDTPCPPNYQRDPVSGFCLKNCPP 5522
Score = 62.0 bits (149), Expect = 1e-09
Identities = 58/234 (24%), Positives = 81/234 (34%), Gaps = 44/234 (18%)
Query: 224 CTAPPGAVQGHWAREAPGAWDCSVENGGCEHACNAIPGAPRCQCPAGAALQADGRSCTA- 282
C P G R +C C H C+ PG+ +C CP G L DG+SC
Sbjct: 5298 CVCPRGYRSQGVGRPCMDINECEQVPKPCAHQCSNTPGSFKCICPPGQHLLGDGKSCAGL 5357
Query: 283 ------SATQSCNDLCEHFCVPNPDQP-----------GSYSCMCETGYRLA-------- 317
S +L V N QP SYS + L+
Sbjct: 5358 ERLPNYGTQYSSYNLARFSPVRNNYQPQQHYRQYSHLYSSYSEYRNSRTSLSRTRRTIRK 5417
Query: 318 -------ADQHRCEDVDDCILEPSPCPQRCVNTQGGFECHCYPNYDLV-DGECVEPVDPC 369
A C D+D+C C C NT G ++C C P Y L +G+ + +D C
Sbjct: 5418 TCPEGSEASHDTCVDIDEC-ENTDACQHECKNTFGSYQCICPPGYQLTHNGKTCQDIDEC 5476
Query: 370 FRANCEYQCQPLN-----QTSYLCVCAEGFAPIPHEPHRCQMFCNQTACPADCD 418
N C P + SY C+ + P ++ FC + P D +
Sbjct: 5477 LEQN--VHCGPNRMCFNMRGSYQCI--DTPCPPNYQRDPVSGFCLKNCPPNDLE 5526
Score = 60.8 bits (146), Expect = 3e-09
Identities = 66/278 (23%), Positives = 97/278 (34%), Gaps = 77/278 (27%)
Query: 304 GSYSCMCETGYRLAADQHRCEDVDDCILEPSPCPQRCVNTQGGFECHCYPNYDL-VDGEC 362
G S C +G+ L + C D D+C +PC C N G + C C + DG
Sbjct: 5086 GDRSNQCPSGFTLDSVGPFCADEDEC-AAGNPCSHSCHNAMGTYYCSCPKGLTIAADGRT 5144
Query: 363 VEPVDPC-----------------------------FRANCE-YQCQPLNQT-------- 384
+ +D C FR + CQ +N+
Sbjct: 5145 CQDIDECALGRHTCHAGQDCDNTIGSYRCVVRCGSGFRRTSDGLSCQDINECQESSPCHQ 5204
Query: 385 -------SYLCVCAEGFAPIPHEPHRCQMF--CNQTAC-PADCDPNTQASCE----CPEG 430
S+ C C G+ + +C C Q C P NT+ + CP G
Sbjct: 5205 RCFNAIGSFHCGCEPGY---QLKGRKCMDVNECRQNVCRPDQHCKNTRGGYKCIDLCPNG 5261
Query: 431 YILDDGFICTDIDECENGGF---CSGVCHNLPGTFECICGPDSALARHIGTDCDSGKVDG 487
+ C DIDEC++G + +C N G++ C+C P ++ +G C
Sbjct: 5262 MTKAENGTCIDIDECKDGTHQCRYNQICENTRGSYRCVC-PRGYRSQGVGRPC------- 5313
Query: 488 GDSGSGEPPPSP-------TPGS--TLTPPAVGLVHSG 516
D E P P TPGS + PP L+ G
Sbjct: 5314 MDINECEQVPKPCAHQCSNTPGSFKCICPPGQHLLGDG 5351
>gi|51873053 fibulin 2 isoform a precursor [Homo sapiens]
Length = 1231
Score = 119 bits (297), Expect = 1e-26
Identities = 88/263 (33%), Positives = 115/263 (43%), Gaps = 58/263 (22%)
Query: 248 ENGGCEHACNAIPGAPRCQCPAGAALQADGRSC-----------TASATQSC-NDLCEHF 295
+NG C+ C+ + G+ C C G A+ ADG SC S Q C N L +
Sbjct: 685 DNGPCKQVCSTVGGSAICSCFPGYAIMADGVSCEDQDECLMGAHDCSRRQFCVNTLGSFY 744
Query: 296 CVPNPDQPGSYSCMCETGYRLAADQHRCEDVDDCILEPSPCP--QRCVNTQGGFECH--- 350
CV +++ +C GY L A +C D+++C+ + C + CVNT G F C+
Sbjct: 745 CV-------NHTVLCADGYILNA-HRKCVDINECVTDLHTCSRGEHCVNTLGSFHCYKAL 796
Query: 351 -CYPNYDLVDGECVEPVDPCFRANCEYQCQP-----LNQTSYLCV----CAEGFAPIPH- 399
C P Y L DGEC E VD C A + CQP + S+ C C +GF P
Sbjct: 797 TCEPGYALKDGEC-EDVDEC--AMGTHTCQPGFLCQNTKGSFYCQARQRCMDGFLQDPEG 853
Query: 400 ------------EPHRCQMFCNQTACPADCDPNTQASCECPEGY-ILDDGFICTDIDECE 446
EP R C T C N C GY DDG C D++ECE
Sbjct: 854 NCVDINECTSLSEPCRPGFSCINTVGSYTCQRNPLI---CARGYHASDDGTKCVDVNECE 910
Query: 447 NGGFCSG---VCHNLPGTFECIC 466
G G VCHNLPG++ C C
Sbjct: 911 TGVHRCGEGQVCHNLPGSYRCDC 933
Score = 109 bits (273), Expect = 6e-24
Identities = 75/239 (31%), Positives = 101/239 (42%), Gaps = 55/239 (23%)
Query: 244 DCSVENGGCEHACNAIPGAPRCQCPAGAALQADGRSC--TASATQSCNDLCEHFCVPNPD 301
+ V G C+ +PG+ RC C AG A GR C S LC+H C +
Sbjct: 910 ETGVHRCGEGQVCHNLPGSYRCDCKAGFQRDAFGRGCIDVNECWASPGRLCQHTC---EN 966
Query: 302 QPGSYSCMCETGYRLAADQHRCEDVDDCILEPSPCPQRCVNTQGGFECHCYPNYDLV-DG 360
GSY C C +G+ LAAD RCEDV++C E C Q C N G ++C+C Y L DG
Sbjct: 967 TLGSYRCSCASGFLLAADGKRCEDVNEC--EAQRCSQECANIYGSYQCYCRQGYQLAEDG 1024
Query: 361 ECVEPVDPCFRAN---CEYQCQPLNQTSYLCVCAEGFAPIPHEPHRCQMFCNQTACPADC 417
+D C + C ++C + SY C C E
Sbjct: 1025 HTCTDIDECAQGAGILCTFRCLNV-PGSYQCACPE------------------------- 1058
Query: 418 DPNTQASCECPEGYILD-DGFICTDIDECENGGF-CS--GVCHNLPGTFECI---CGPD 469
+GY + +G C D+DEC G CS CHN+ G+F C+ C P+
Sbjct: 1059 -----------QGYTMTANGRSCKDVDECALGTHNCSEAETCHNIQGSFRCLRFECPPN 1106
Score = 94.4 bits (233), Expect = 3e-19
Identities = 79/274 (28%), Positives = 114/274 (41%), Gaps = 45/274 (16%)
Query: 246 SVENGGCEHACNAIPGAPRCQCPAGAALQADGRSCTASATQ------------SCNDLCE 293
++++G CE G CQ G Q S A Q +C D+ E
Sbjct: 803 ALKDGECEDVDECAMGTHTCQ--PGFLCQNTKGSFYCQARQRCMDGFLQDPEGNCVDINE 860
Query: 294 HFCVPNPDQPG--------SYSC-----MCETGYRLAADQHRCEDVDDCILEPSPCP--Q 338
+ P +PG SY+C +C GY + D +C DV++C C Q
Sbjct: 861 CTSLSEPCRPGFSCINTVGSYTCQRNPLICARGYHASDDGTKCVDVNECETGVHRCGEGQ 920
Query: 339 RCVNTQGGFECHCYPNY--DLVDGECVEPVDPCFRAN---CEYQCQPLNQTSYLCVCAEG 393
C N G + C C + D C++ V+ C+ + C++ C+ SY C CA G
Sbjct: 921 VCHNLPGSYRCDCKAGFQRDAFGRGCID-VNECWASPGRLCQHTCEN-TLGSYRCSCASG 978
Query: 394 FAPIPHEPHRCQMF--CNQTACPADCDPNTQAS--CECPEGYIL-DDGFICTDIDECENG 448
F + + RC+ C C +C N S C C +GY L +DG CTDIDEC G
Sbjct: 979 FL-LAADGKRCEDVNECEAQRCSQEC-ANIYGSYQCYCRQGYQLAEDGHTCTDIDECAQG 1036
Query: 449 G--FCSGVCHNLPGTFECICGPDSALARHIGTDC 480
C+ C N+PG+++C C G C
Sbjct: 1037 AGILCTFRCLNVPGSYQCACPEQGYTMTANGRSC 1070
Score = 81.3 bits (199), Expect = 2e-15
Identities = 61/194 (31%), Positives = 75/194 (38%), Gaps = 40/194 (20%)
Query: 224 CTAPPGAVQGHWAREAPGAWDCSVENG-------------------GCEHACNAIPGAPR 264
C A PG + H G++ CS +G C C I G+ +
Sbjct: 952 CWASPGRLCQHTCENTLGSYRCSCASGFLLAADGKRCEDVNECEAQRCSQECANIYGSYQ 1011
Query: 265 CQCPAGAALQADGRSCT--ASATQSCNDLCEHFCVPNPDQPGSYSCMC-ETGYRLAADQH 321
C C G L DG +CT Q LC C+ + PGSY C C E GY + A+
Sbjct: 1012 CYCRQGYQLAEDGHTCTDIDECAQGAGILCTFRCL---NVPGSYQCACPEQGYTMTANGR 1068
Query: 322 RCEDVDDCILEPSPC--PQRCVNTQGGFEC---HCYPNYDLVDGECVEPVDPCFRANC-- 374
C+DVD+C L C + C N QG F C C PNY V C R C
Sbjct: 1069 SCKDVDECALGTHNCSEAETCHNIQGSFRCLRFECPPNYVQVS------KTKCERTTCHD 1122
Query: 375 --EYQCQPLNQTSY 386
E Q P T Y
Sbjct: 1123 FLECQNSPARITHY 1136
Score = 81.3 bits (199), Expect = 2e-15
Identities = 54/171 (31%), Positives = 75/171 (43%), Gaps = 19/171 (11%)
Query: 252 CEHACNAIPGAPRCQCPAGAALQADGRSC---TASATQSCNDLCEHFCVPNPDQPGSYSC 308
C+H C G+ RC C +G L ADG+ C Q C+ C + GSY C
Sbjct: 960 CQHTCENTLGSYRCSCASGFLLAADGKRCEDVNECEAQRCSQECANIY-------GSYQC 1012
Query: 309 MCETGYRLAADQHRCEDVDDCILEPS-PCPQRCVNTQGGFECHC-YPNYDL-VDGECVEP 365
C GY+LA D H C D+D+C C RC+N G ++C C Y + +G +
Sbjct: 1013 YCRQGYQLAEDGHTCTDIDECAQGAGILCTFRCLNVPGSYQCACPEQGYTMTANGRSCKD 1072
Query: 366 VDPCFRA--NC-EYQCQPLNQTSYLCVCAEGFAPIPHEPHRCQMFCNQTAC 413
VD C NC E + Q S+ C+ F P+ + C +T C
Sbjct: 1073 VDECALGTHNCSEAETCHNIQGSFRCL---RFECPPNYVQVSKTKCERTTC 1120
>gi|31377568 signal peptide, CUB domain, EGF-like 3 [Homo sapiens]
Length = 993
Score = 117 bits (293), Expect = 3e-26
Identities = 79/272 (29%), Positives = 107/272 (39%), Gaps = 59/272 (21%)
Query: 248 ENGGCEHACNAIPGAPRCQCPAGAALQADGRSC--TASATQSCNDLCEHFCVPNPDQPGS 305
+N + C P + +C C +G DG+ C + N C H CV + PG+
Sbjct: 38 DNCHIDAICQNTPRSYKCICKSGYT--GDGKHCKDVDECEREDNAGCVHDCV---NIPGN 92
Query: 306 YSCMCETGYRLAADQHRCEDVDDCILEPSPCPQRCVNTQGGFECHCYPNYDLVDGE--CV 363
Y C C G+ LA D H C DVD+C C Q CVN G +ECHC + L D + C+
Sbjct: 93 YRCTCYDGFHLAHDGHNCLDVDECAEGNGGCQQSCVNMMGSYECHCREGFFLSDNQHTCI 152
Query: 364 EPVDP---CFRAN--CEYQCQPLNQTSYLCVCAEGFAPIPHEPHRCQMFC---------- 408
+ + C N C + C+ + C C GF + C++ C
Sbjct: 153 QRPEEGMNCMNKNHGCAHICRETPKGGIACECRPGF-ELTKNQRDCKLTCNYGNGGCQHT 211
Query: 409 -------------------------------NQTACPADC-DPNTQASCECPEGYILD-D 435
N C + C D T C CP G++L D
Sbjct: 212 CDDTEQGPRCGCHIKFVLHTDGKTCIETCAVNNGGCDSKCHDAATGVHCTCPVGFMLQPD 271
Query: 436 GFICTDIDECE-NGGFCSGVCHNLPGTFECIC 466
C DIDEC N G C +C N G+FEC C
Sbjct: 272 RKTCKDIDECRLNNGGCDHICRNTVGSFECSC 303
Score = 114 bits (285), Expect = 2e-25
Identities = 74/253 (29%), Positives = 99/253 (39%), Gaps = 45/253 (17%)
Query: 245 CSVENGGCEHACNAIPGAPRCQCPAGAALQADGRSCTASATQSCNDLCEHFCVPNPDQPG 304
C+ NGGC+H C+ PRC C L DG++C + + N C+ C D
Sbjct: 201 CNYGNGGCQHTCDDTEQGPRCGCHIKFVLHTDGKTCIETCAVN-NGGCDSKC---HDAAT 256
Query: 305 SYSCMCETGYRLAADQHRCEDVDDCILEPSPCPQRCVNTQGGFECHCYPNYDLVDGECVE 364
C C G+ L D+ C+D+D+C L C C NT G FEC C Y L+ E
Sbjct: 257 GVHCTCPVGFMLQPDRKTCKDIDECRLNNGGCDHICRNTVGSFECSCKKGYKLLINE--- 313
Query: 365 PVDPCFRANCEYQCQPLNQTSYLCVCAEGFAPIPHEPHRCQMFCNQTACPADCDPNTQAS 424
CQ +++ S+ C H C NT S
Sbjct: 314 -----------RNCQDIDECSFDRTC----------DHICV--------------NTPGS 338
Query: 425 --CECPEGYILDDGFICTDIDECE-NGGFCSGVCHNLPGTFECICGPDSALARHIGTDCD 481
C C GY+L C D+DEC N G C C N PG+++C C G DC
Sbjct: 339 FQCLCHRGYLLYGITHCGDVDECSINRGGCRFGCINTPGSYQCTCPAGQGRLHWNGKDCT 398
Query: 482 SGKVDGGDSGSGE 494
G G+ +
Sbjct: 399 EPLKCQGSPGASK 411
Score = 102 bits (255), Expect = 7e-22
Identities = 72/257 (28%), Positives = 102/257 (39%), Gaps = 22/257 (8%)
Query: 224 CTAPPGAVQGHWAREAPGAWDCSVENGGCEHACNAIPGAPRCQCPAGAALQADGRSCTAS 283
CT G H +C+ NGGC+ +C + G+ C C G L + +C
Sbjct: 95 CTCYDGFHLAHDGHNCLDVDECAEGNGGCQQSCVNMMGSYECHCREGFFLSDNQHTCIQR 154
Query: 284 ATQSCNDL-----CEHFCVPNPDQPGSYSCMCETGYRLAADQHRCEDVDDCILEPSPCPQ 338
+ N + C H C P G +C C G+ L +Q C+ C C
Sbjct: 155 PEEGMNCMNKNHGCAHICRETPK--GGIACECRPGFELTKNQRDCKLT--CNYGNGGCQH 210
Query: 339 RCVNTQGGFECHCYPNYDL-VDGECVEPVDPCFRANCEYQCQPLNQTSYLCVCAEGFAPI 397
C +T+ G C C+ + L DG+ C+ +C T C C GF
Sbjct: 211 TCDDTEQGPRCGCHIKFVLHTDGKTCIETCAVNNGGCDSKCHDA-ATGVHCTCPVGFMLQ 269
Query: 398 PHEP-----HRCQMFCNQTACPADCDPNTQAS--CECPEGY-ILDDGFICTDIDECENGG 449
P C++ N C C NT S C C +GY +L + C DIDEC
Sbjct: 270 PDRKTCKDIDECRL--NNGGCDHICR-NTVGSFECSCKKGYKLLINERNCQDIDECSFDR 326
Query: 450 FCSGVCHNLPGTFECIC 466
C +C N PG+F+C+C
Sbjct: 327 TCDHICVNTPGSFQCLC 343
Score = 92.0 bits (227), Expect = 1e-18
Identities = 44/128 (34%), Positives = 62/128 (48%), Gaps = 4/128 (3%)
Query: 224 CTAPPGAVQGHWAREAPGAWDCSVENGGCEHACNAIPGAPRCQCPAGAALQADGRSCTAS 283
CT P G + + +C + NGGC+H C G+ C C G L + R+C
Sbjct: 260 CTCPVGFMLQPDRKTCKDIDECRLNNGGCDHICRNTVGSFECSCKKGYKLLINERNCQDI 319
Query: 284 ATQSCNDLCEHFCVPNPDQPGSYSCMCETGYRLAADQHRCEDVDDCILEPSPCPQRCVNT 343
S + C+H CV + PGS+ C+C GY L H C DVD+C + C C+NT
Sbjct: 320 DECSFDRTCDHICV---NTPGSFQCLCHRGYLLYGITH-CGDVDECSINRGGCRFGCINT 375
Query: 344 QGGFECHC 351
G ++C C
Sbjct: 376 PGSYQCTC 383
Score = 43.9 bits (102), Expect = 4e-04
Identities = 27/90 (30%), Positives = 37/90 (41%), Gaps = 21/90 (23%)
Query: 244 DCSVENGGCEHACNAIPGAPRCQCPAG-AALQADGRSCT-----------ASATQSCN-- 289
+CS+ GGC C PG+ +C CPAG L +G+ CT + A SCN
Sbjct: 360 ECSINRGGCRFGCINTPGSYQCTCPAGQGRLHWNGKDCTEPLKCQGSPGASKAMLSCNRS 419
Query: 290 ---DLCEHFCVPN----PDQPGSYSCMCET 312
D C C P+ ++ C T
Sbjct: 420 GKKDTCALTCPSRARFLPESENGFTVSCGT 449
>gi|120587029 signal peptide, CUB domain, EGF-like 1 [Homo sapiens]
Length = 988
Score = 116 bits (291), Expect = 5e-26
Identities = 72/244 (29%), Positives = 103/244 (42%), Gaps = 47/244 (19%)
Query: 245 CSVENGGCEHACNAIPGAPRCQCPAGAALQADGRSCTASATQSCNDLCEHFCVPNPDQPG 304
C+ NGGC+H+C P C C AL +DGR+C + + N C+ C D
Sbjct: 206 CNYGNGGCQHSCEDTDTGPTCGCHQKYALHSDGRTCIETCAVN-NGGCDRTC---KDTAT 261
Query: 305 SYSCMCETGYRLAADQHRCEDVDDCILEPSPCPQRCVNTQGGFECHCYPNYDLV-DGECV 363
C C G+ L D C+D+++C++ C C NT G FEC C Y L+ D
Sbjct: 262 GVRCSCPVGFTLQPDGKTCKDINECLVNNGGCDHFCRNTVGSFECGCRKGYKLLTDERTC 321
Query: 364 EPVDPC-FRANCEYQCQPLNQTSYLCVCAEGFAPIPHEPHRCQMFCNQTACPADCDPNTQ 422
+ +D C F C+ ++C+ + G
Sbjct: 322 QDIDECSFERTCD----------HICINSPG----------------------------S 343
Query: 423 ASCECPEGYILDDGFICTDIDECE-NGGFCSGVCHNLPGTFECICGPDSALARHIGTDC- 480
C C GYIL C D+DEC + G C C N G++EC+C P L + G DC
Sbjct: 344 FQCLCHRGYILYGTTHCGDVDECSMSNGSCDQGCVNTKGSYECVCPPGRRLHWN-GKDCV 402
Query: 481 DSGK 484
++GK
Sbjct: 403 ETGK 406
Score = 111 bits (277), Expect = 2e-24
Identities = 88/300 (29%), Positives = 118/300 (39%), Gaps = 62/300 (20%)
Query: 249 NGGCEHACNAIPGAPRCQCPAGAALQADGRSCT-ASATQSCNDLCEHFCVPNPDQPGSYS 307
NGGC H C IPG RC C G L DG +C Q N C+ CV + GSY
Sbjct: 84 NGGCVHECINIPGNYRCTCFDGFMLAHDGHNCLDVDECQDNNGGCQQICV---NAMGSYE 140
Query: 308 CMCETGYRLAADQHRC----EDVDDCILEPSPCPQRCVNT-QGGFECHCYPNYDLVDGEC 362
C C +G+ L+ +QH C + +C+ + C C T +GG C C P +DL +
Sbjct: 141 CQCHSGFFLSDNQHTCIHRSNEGMNCMNKDHGCAHICRETPKGGVACDCRPGFDLAQNQ- 199
Query: 363 VEPVDPCFRAN--CEYQCQPLNQTSYLCVCAEGFAPIPHEPHRCQMFC--NQTACPADC- 417
+ C N C++ C+ + T C C + +A + + C C N C C
Sbjct: 200 KDCTLTCNYGNGGCQHSCEDTD-TGPTCGCHQKYA-LHSDGRTCIETCAVNNGGCDRTCK 257
Query: 418 DPNTQASCECPEGYILD-DGFICTDIDEC--ENGGF------------------------ 450
D T C CP G+ L DG C DI+EC NGG
Sbjct: 258 DTATGVRCSCPVGFTLQPDGKTCKDINECLVNNGGCDHFCRNTVGSFECGCRKGYKLLTD 317
Query: 451 ---------------CSGVCHNLPGTFECICGPDSAL--ARHIGTDCDSGKVDGGDSGSG 493
C +C N PG+F+C+C L H G D D + G G
Sbjct: 318 ERTCQDIDECSFERTCDHICINSPGSFQCLCHRGYILYGTTHCG-DVDECSMSNGSCDQG 376
Score = 106 bits (265), Expect = 5e-23
Identities = 81/285 (28%), Positives = 108/285 (37%), Gaps = 63/285 (22%)
Query: 240 PGAWD---CSVENGGC--EHACNAIPGAPRCQCPAGAALQADGRSCT---ASATQSCNDL 291
PG+ D CS C + C P + +C C G + +G+ C N
Sbjct: 29 PGSVDVDECSEGTDDCHIDAICQNTPKSYKCLCKPG--YKGEGKQCEDIDECENDYYNGG 86
Query: 292 CEHFCVPNPDQPGSYSCMCETGYRLAADQHRCEDVDDCILEPSPCPQRCVNTQGGFECHC 351
C H C+ + PG+Y C C G+ LA D H C DVD+C C Q CVN G +EC C
Sbjct: 87 CVHECI---NIPGNYRCTCFDGFMLAHDGHNCLDVDECQDNNGGCQQICVNAMGSYECQC 143
Query: 352 YPNYDLVDGE--CVEPVDP---CFRAN--CEYQCQPLNQTSYLCVCAEGFAPIPHEPH-- 402
+ + L D + C+ + C + C + C+ + C C GF ++
Sbjct: 144 HSGFFLSDNQHTCIHRSNEGMNCMNKDHGCAHICRETPKGGVACDCRPGFDLAQNQKDCT 203
Query: 403 --------RCQMFCNQT------------------------------ACPADC-DPNTQA 423
CQ C T C C D T
Sbjct: 204 LTCNYGNGGCQHSCEDTDTGPTCGCHQKYALHSDGRTCIETCAVNNGGCDRTCKDTATGV 263
Query: 424 SCECPEGYILD-DGFICTDIDEC-ENGGFCSGVCHNLPGTFECIC 466
C CP G+ L DG C DI+EC N G C C N G+FEC C
Sbjct: 264 RCSCPVGFTLQPDGKTCKDINECLVNNGGCDHFCRNTVGSFECGC 308
Score = 99.8 bits (247), Expect = 6e-21
Identities = 52/143 (36%), Positives = 68/143 (47%), Gaps = 6/143 (4%)
Query: 224 CTAPPGAVQGHWAREAPGAWDCSVENGGCEHACNAIPGAPRCQCPAGAALQADGRSCTAS 283
C+ P G + +C V NGGC+H C G+ C C G L D R+C
Sbjct: 265 CSCPVGFTLQPDGKTCKDINECLVNNGGCDHFCRNTVGSFECGCRKGYKLLTDERTCQDI 324
Query: 284 ATQSCNDLCEHFCVPNPDQPGSYSCMCETGYRLAADQHRCEDVDDCILEPSPCPQRCVNT 343
S C+H C+ + PGS+ C+C GY L H C DVD+C + C Q CVNT
Sbjct: 325 DECSFERTCDHICI---NSPGSFQCLCHRGYILYGTTH-CGDVDECSMSNGSCDQGCVNT 380
Query: 344 QGGFECHCYPNYDL--VDGECVE 364
+G +EC C P L +CVE
Sbjct: 381 KGSYECVCPPGRRLHWNGKDCVE 403
Score = 31.2 bits (69), Expect = 2.7
Identities = 11/31 (35%), Positives = 17/31 (54%), Gaps = 3/31 (9%)
Query: 441 DIDECENGG---FCSGVCHNLPGTFECICGP 468
D+DEC G +C N P +++C+C P
Sbjct: 33 DVDECSEGTDDCHIDAICQNTPKSYKCLCKP 63
>gi|51873055 fibulin 2 isoform b precursor [Homo sapiens]
Length = 1184
Score = 115 bits (288), Expect = 1e-25
Identities = 118/392 (30%), Positives = 148/392 (37%), Gaps = 115/392 (29%)
Query: 154 EEQQCEVKAD-GFLCEFHFPATCR---PLAV-------EPGAAAAAVSITYGTPFAARGA 202
E Q CE + G+ C + C PL V EP AA VS A A
Sbjct: 531 EGQSCESNPNLGYPCNHVMLSCCEGEEPLIVPEVRRPPEPAAAPRRVS-------EAEMA 583
Query: 203 DFQALPVGSSAAVA---PLGLQLMCTAPPGAVQGHWAREAPGAWDCSVENGGCEHACNAI 259
+AL +G+ A + P Q C PG + C+H C
Sbjct: 584 GREALSLGTEAELPNSLPGDDQDECLLLPGEL--------------------CQHLCINT 623
Query: 260 PGAPRCQCPAGAALQADGRSC-----------------------TASAT--------QSC 288
G+ C C G +LQ DGR+C AS T +C
Sbjct: 624 VGSYHCACFPGFSLQDDGRTCRPEGHPPQPEAPQEPALKSEFSQVASNTIPLPLPQPNTC 683
Query: 289 ND--LCEHFCVPNPDQPGSYSCMCETGYRLAADQHRCEDVDDCILEPSPCP--QRCVNTQ 344
D C+ C GS C C GY + AD CED+++C+ + C + CVNT
Sbjct: 684 KDNGPCKQVC---STVGGSAICSCFPGYAIMADGVSCEDINECVTDLHTCSRGEHCVNTL 740
Query: 345 GGFECH----CYPNYDLVDGECVEPVDPCFRANCEYQCQP-----LNQTSYLCV----CA 391
G F C+ C P Y L DGEC E VD C A + CQP + S+ C C
Sbjct: 741 GSFHCYKALTCEPGYALKDGEC-EDVDEC--AMGTHTCQPGFLCQNTKGSFYCQARQRCM 797
Query: 392 EGFAPIPH-------------EPHRCQMFCNQTACPADCDPNTQASCECPEGY-ILDDGF 437
+GF P EP R C T C N C GY DDG
Sbjct: 798 DGFLQDPEGNCVDINECTSLSEPCRPGFSCINTVGSYTCQRNPLI---CARGYHASDDGT 854
Query: 438 ICTDIDECENGGFCSG---VCHNLPGTFECIC 466
C D++ECE G G VCHNLPG++ C C
Sbjct: 855 KCVDVNECETGVHRCGEGQVCHNLPGSYRCDC 886
Score = 109 bits (273), Expect = 6e-24
Identities = 75/239 (31%), Positives = 101/239 (42%), Gaps = 55/239 (23%)
Query: 244 DCSVENGGCEHACNAIPGAPRCQCPAGAALQADGRSC--TASATQSCNDLCEHFCVPNPD 301
+ V G C+ +PG+ RC C AG A GR C S LC+H C +
Sbjct: 863 ETGVHRCGEGQVCHNLPGSYRCDCKAGFQRDAFGRGCIDVNECWASPGRLCQHTC---EN 919
Query: 302 QPGSYSCMCETGYRLAADQHRCEDVDDCILEPSPCPQRCVNTQGGFECHCYPNYDLV-DG 360
GSY C C +G+ LAAD RCEDV++C E C Q C N G ++C+C Y L DG
Sbjct: 920 TLGSYRCSCASGFLLAADGKRCEDVNEC--EAQRCSQECANIYGSYQCYCRQGYQLAEDG 977
Query: 361 ECVEPVDPCFRAN---CEYQCQPLNQTSYLCVCAEGFAPIPHEPHRCQMFCNQTACPADC 417
+D C + C ++C + SY C C E
Sbjct: 978 HTCTDIDECAQGAGILCTFRCLNV-PGSYQCACPE------------------------- 1011
Query: 418 DPNTQASCECPEGYILD-DGFICTDIDECENGGF-CS--GVCHNLPGTFECI---CGPD 469
+GY + +G C D+DEC G CS CHN+ G+F C+ C P+
Sbjct: 1012 -----------QGYTMTANGRSCKDVDECALGTHNCSEAETCHNIQGSFRCLRFECPPN 1059
Score = 94.4 bits (233), Expect = 3e-19
Identities = 79/274 (28%), Positives = 114/274 (41%), Gaps = 45/274 (16%)
Query: 246 SVENGGCEHACNAIPGAPRCQCPAGAALQADGRSCTASATQ------------SCNDLCE 293
++++G CE G CQ G Q S A Q +C D+ E
Sbjct: 756 ALKDGECEDVDECAMGTHTCQ--PGFLCQNTKGSFYCQARQRCMDGFLQDPEGNCVDINE 813
Query: 294 HFCVPNPDQPG--------SYSC-----MCETGYRLAADQHRCEDVDDCILEPSPCP--Q 338
+ P +PG SY+C +C GY + D +C DV++C C Q
Sbjct: 814 CTSLSEPCRPGFSCINTVGSYTCQRNPLICARGYHASDDGTKCVDVNECETGVHRCGEGQ 873
Query: 339 RCVNTQGGFECHCYPNY--DLVDGECVEPVDPCFRAN---CEYQCQPLNQTSYLCVCAEG 393
C N G + C C + D C++ V+ C+ + C++ C+ SY C CA G
Sbjct: 874 VCHNLPGSYRCDCKAGFQRDAFGRGCID-VNECWASPGRLCQHTCEN-TLGSYRCSCASG 931
Query: 394 FAPIPHEPHRCQMF--CNQTACPADCDPNTQAS--CECPEGYIL-DDGFICTDIDECENG 448
F + + RC+ C C +C N S C C +GY L +DG CTDIDEC G
Sbjct: 932 FL-LAADGKRCEDVNECEAQRCSQEC-ANIYGSYQCYCRQGYQLAEDGHTCTDIDECAQG 989
Query: 449 G--FCSGVCHNLPGTFECICGPDSALARHIGTDC 480
C+ C N+PG+++C C G C
Sbjct: 990 AGILCTFRCLNVPGSYQCACPEQGYTMTANGRSC 1023
Score = 81.3 bits (199), Expect = 2e-15
Identities = 61/194 (31%), Positives = 75/194 (38%), Gaps = 40/194 (20%)
Query: 224 CTAPPGAVQGHWAREAPGAWDCSVENG-------------------GCEHACNAIPGAPR 264
C A PG + H G++ CS +G C C I G+ +
Sbjct: 905 CWASPGRLCQHTCENTLGSYRCSCASGFLLAADGKRCEDVNECEAQRCSQECANIYGSYQ 964
Query: 265 CQCPAGAALQADGRSCT--ASATQSCNDLCEHFCVPNPDQPGSYSCMC-ETGYRLAADQH 321
C C G L DG +CT Q LC C+ + PGSY C C E GY + A+
Sbjct: 965 CYCRQGYQLAEDGHTCTDIDECAQGAGILCTFRCL---NVPGSYQCACPEQGYTMTANGR 1021
Query: 322 RCEDVDDCILEPSPC--PQRCVNTQGGFEC---HCYPNYDLVDGECVEPVDPCFRANC-- 374
C+DVD+C L C + C N QG F C C PNY V C R C
Sbjct: 1022 SCKDVDECALGTHNCSEAETCHNIQGSFRCLRFECPPNYVQVS------KTKCERTTCHD 1075
Query: 375 --EYQCQPLNQTSY 386
E Q P T Y
Sbjct: 1076 FLECQNSPARITHY 1089
Score = 81.3 bits (199), Expect = 2e-15
Identities = 54/171 (31%), Positives = 75/171 (43%), Gaps = 19/171 (11%)
Query: 252 CEHACNAIPGAPRCQCPAGAALQADGRSC---TASATQSCNDLCEHFCVPNPDQPGSYSC 308
C+H C G+ RC C +G L ADG+ C Q C+ C + GSY C
Sbjct: 913 CQHTCENTLGSYRCSCASGFLLAADGKRCEDVNECEAQRCSQECANIY-------GSYQC 965
Query: 309 MCETGYRLAADQHRCEDVDDCILEPS-PCPQRCVNTQGGFECHC-YPNYDL-VDGECVEP 365
C GY+LA D H C D+D+C C RC+N G ++C C Y + +G +
Sbjct: 966 YCRQGYQLAEDGHTCTDIDECAQGAGILCTFRCLNVPGSYQCACPEQGYTMTANGRSCKD 1025
Query: 366 VDPCFRA--NC-EYQCQPLNQTSYLCVCAEGFAPIPHEPHRCQMFCNQTAC 413
VD C NC E + Q S+ C+ F P+ + C +T C
Sbjct: 1026 VDECALGTHNCSEAETCHNIQGSFRCL---RFECPPNYVQVSKTKCERTTC 1073
>gi|34734064 fibulin 1 isoform B precursor [Homo sapiens]
Length = 601
Score = 113 bits (282), Expect = 5e-25
Identities = 82/252 (32%), Positives = 113/252 (44%), Gaps = 30/252 (11%)
Query: 252 CEHACNAIPGAPRCQCPAGAALQADGRSCTASATQSCNDLCE--HFCVPNPDQPGSYSCM 309
C++ + P+ QC +G A G + S + C H C+ + GSY+C
Sbjct: 279 CQNTLGSFRCRPKLQCKSGFIQDALGNCIDINECLSISAPCPIGHTCI---NTEGSYTCQ 335
Query: 310 -----CETGYRLAADQHRCEDVDDCILEPSPCPQ--RCVNTQGGFECHCYPNY--DLVDG 360
C GY L + RC DVD+C PC + RCVN+ G F C C Y D +
Sbjct: 336 KNVPNCGRGYHLNEEGTRCVDVDECAPPAEPCGKGHRCVNSPGSFRCECKTGYYFDGISR 395
Query: 361 ECVEPVDPCFRAN---CEYQCQPLNQTSYLCVCAEGFAPIPHEPHRCQMF--CNQTACPA 415
CV+ V+ C R C ++C+ SYLC C+ GF + + C+ C+ + C
Sbjct: 396 MCVD-VNECQRYPGRLCGHKCEN-TLGSYLCSCSVGFR-LSVDGRSCEDINECSSSPCSQ 452
Query: 416 DCDPNTQAS--CECPEGYILDD--GFICTDIDECE---NGGFCSGVCHNLPGTFECICGP 468
+C N S C C GY L D G C DIDEC G CS C N+PG+F+C C
Sbjct: 453 EC-ANVYGSYQCYCRRGYQLSDVDGVTCEDIDECALPTGGHICSYRCINIPGSFQCSCPS 511
Query: 469 DSALARHIGTDC 480
G +C
Sbjct: 512 SGYRLAPNGRNC 523
Score = 100 bits (250), Expect = 3e-21
Identities = 75/236 (31%), Positives = 93/236 (39%), Gaps = 53/236 (22%)
Query: 239 APGAWDCSVENGGCEHACNAIPGAPRCQCPAGAALQADGRSCTA--SATQSCNDLCEHFC 296
AP A C G H C PG+ RC+C G R C + LC H C
Sbjct: 361 APPAEPC-----GKGHRCVNSPGSFRCECKTGYYFDGISRMCVDVNECQRYPGRLCGHKC 415
Query: 297 VPNPDQPGSYSCMCETGYRLAADQHRCEDVDDCILEPSPCPQRCVNTQGGFECHCYPNYD 356
+ GSY C C G+RL+ D CED+++C SPC Q C N G ++C+C Y
Sbjct: 416 ---ENTLGSYLCSCSVGFRLSVDGRSCEDINEC--SSSPCSQECANVYGSYQCYCRRGYQ 470
Query: 357 L--VDGECVEPVDPCFRANCEYQCQPLNQTSYLCVCAEGFAPIPHEPHRCQMFCNQTACP 414
L VDG E +D C + C SY C+ G
Sbjct: 471 LSDVDGVTCEDIDECALPTGGHIC------SYRCINIPG--------------------- 503
Query: 415 ADCDPNTQASCECPE-GYIL-DDGFICTDIDECENG-GFCS--GVCHNLPGTFECI 465
C CP GY L +G C DIDEC G CS C N+ G F C+
Sbjct: 504 -------SFQCSCPSSGYRLAPNGRNCQDIDECVTGIHNCSINETCFNIQGGFRCL 552
Score = 70.5 bits (171), Expect = 4e-12
Identities = 63/233 (27%), Positives = 94/233 (40%), Gaps = 34/233 (14%)
Query: 134 GPLCVAVSAAEATVPSEPIWEEQQCEVKADGFLCEFHFPATCRPLAVEPGAAAAAVSITY 193
G CV V E P+EP + +C F CE C+ G + V +
Sbjct: 351 GTRCVDVD--ECAPPAEPCGKGHRCVNSPGSFRCE------CKTGYYFDGISRMCVDVNE 402
Query: 194 GTPFAARGADFQA-LPVGSSAAVAPLGLQLMCTAPPGAVQGHWAREAPGAWDCSVENGGC 252
+ R + +GS +G +L +V G R +CS + C
Sbjct: 403 CQRYPGRLCGHKCENTLGSYLCSCSVGFRL-------SVDG---RSCEDINECS--SSPC 450
Query: 253 EHACNAIPGAPRCQCPAGAAL-QADGRSC---TASATQSCNDLCEHFCVPNPDQPGSYSC 308
C + G+ +C C G L DG +C A + +C + C+ + PGS+ C
Sbjct: 451 SQECANVYGSYQCYCRRGYQLSDVDGVTCEDIDECALPTGGHICSYRCI---NIPGSFQC 507
Query: 309 MC-ETGYRLAADQHRCEDVDDCILEPSPCP--QRCVNTQGGFEC---HCYPNY 355
C +GYRLA + C+D+D+C+ C + C N QGGF C C NY
Sbjct: 508 SCPSSGYRLAPNGRNCQDIDECVTGIHNCSINETCFNIQGGFRCLAFECPENY 560
Score = 69.7 bits (169), Expect = 7e-12
Identities = 58/212 (27%), Positives = 81/212 (38%), Gaps = 50/212 (23%)
Query: 292 CEHFCVPNPDQPGSYSCMCETGYRLAADQHRCEDVDDCILEPSPC--PQRCVNTQGGFEC 349
C+ C D+ C C GY+L +D CEDV++CI C + C+NT G F C
Sbjct: 186 CKQQCRDTGDE---VVCSCFVGYQLLSDGVSCEDVNECITGSHSCRLGESCINTVGSFRC 242
Query: 350 H----CYPNYDLVDGECVEPVDPCFRA--NC-----------EYQCQPLNQ--TSYL--- 387
C Y+L + + +D C NC ++C+P Q + ++
Sbjct: 243 QRDSSCGTGYELTEDNSCKDIDECESGIHNCLPDFICQNTLGSFRCRPKLQCKSGFIQDA 302
Query: 388 ---------CVCAEGFAPIPHEPHRCQMFCNQTACPADCDPNTQASCECPEGYIL-DDGF 437
C+ PI H C T C N C GY L ++G
Sbjct: 303 LGNCIDINECLSISAPCPIGHT-------CINTEGSYTCQKNVP---NCGRGYHLNEEGT 352
Query: 438 ICTDIDECENGGFCSGV---CHNLPGTFECIC 466
C D+DEC G C N PG+F C C
Sbjct: 353 RCVDVDECAPPAEPCGKGHRCVNSPGSFRCEC 384
Score = 54.3 bits (129), Expect = 3e-07
Identities = 54/209 (25%), Positives = 77/209 (36%), Gaps = 44/209 (21%)
Query: 267 CPAGAALQADGRSCTASAT--QSCNDLCEHFCVPNPDQPG-SYSCMCETGYRLAADQHRC 323
C G A QA G+SC S C + CV + + + ET + ++ +
Sbjct: 113 CLLGRAAQAQGQSCEYSLMVGYQCGQVFRACCVKSQETGDLDVGGLQETDKIIEVEEEQ- 171
Query: 324 ED--VDDCILEPSPCPQRCVNTQGGFECHCYPNYDLV-DGECVEPVDPCFRANCEYQCQP 380
ED ++D PC Q+C +T C C+ Y L+ DG E V+ C +
Sbjct: 172 EDPYLNDRCRGGGPCKQQCRDTGDEVVCSCFVGYQLLSDGVSCEDVNECITGS------- 224
Query: 381 LNQTSYLCVCAEGFAPIPHEPHRCQM--FCNQTACPADCDPNTQASCECPEGYILDDGFI 438
H C++ C T C Q C GY L +
Sbjct: 225 ---------------------HSCRLGESCINTVGSFRC----QRDSSCGTGYELTEDNS 259
Query: 439 CTDIDECENG---GFCSGVCHNLPGTFEC 464
C DIDECE+G +C N G+F C
Sbjct: 260 CKDIDECESGIHNCLPDFICQNTLGSFRC 288
>gi|34734068 fibulin 1 isoform A precursor [Homo sapiens]
Length = 566
Score = 113 bits (282), Expect = 5e-25
Identities = 82/252 (32%), Positives = 113/252 (44%), Gaps = 30/252 (11%)
Query: 252 CEHACNAIPGAPRCQCPAGAALQADGRSCTASATQSCNDLCE--HFCVPNPDQPGSYSCM 309
C++ + P+ QC +G A G + S + C H C+ + GSY+C
Sbjct: 279 CQNTLGSFRCRPKLQCKSGFIQDALGNCIDINECLSISAPCPIGHTCI---NTEGSYTCQ 335
Query: 310 -----CETGYRLAADQHRCEDVDDCILEPSPCPQ--RCVNTQGGFECHCYPNY--DLVDG 360
C GY L + RC DVD+C PC + RCVN+ G F C C Y D +
Sbjct: 336 KNVPNCGRGYHLNEEGTRCVDVDECAPPAEPCGKGHRCVNSPGSFRCECKTGYYFDGISR 395
Query: 361 ECVEPVDPCFRAN---CEYQCQPLNQTSYLCVCAEGFAPIPHEPHRCQMF--CNQTACPA 415
CV+ V+ C R C ++C+ SYLC C+ GF + + C+ C+ + C
Sbjct: 396 MCVD-VNECQRYPGRLCGHKCEN-TLGSYLCSCSVGFR-LSVDGRSCEDINECSSSPCSQ 452
Query: 416 DCDPNTQAS--CECPEGYILDD--GFICTDIDECE---NGGFCSGVCHNLPGTFECICGP 468
+C N S C C GY L D G C DIDEC G CS C N+PG+F+C C
Sbjct: 453 EC-ANVYGSYQCYCRRGYQLSDVDGVTCEDIDECALPTGGHICSYRCINIPGSFQCSCPS 511
Query: 469 DSALARHIGTDC 480
G +C
Sbjct: 512 SGYRLAPNGRNC 523
Score = 100 bits (250), Expect = 3e-21
Identities = 75/236 (31%), Positives = 93/236 (39%), Gaps = 53/236 (22%)
Query: 239 APGAWDCSVENGGCEHACNAIPGAPRCQCPAGAALQADGRSCTA--SATQSCNDLCEHFC 296
AP A C G H C PG+ RC+C G R C + LC H C
Sbjct: 361 APPAEPC-----GKGHRCVNSPGSFRCECKTGYYFDGISRMCVDVNECQRYPGRLCGHKC 415
Query: 297 VPNPDQPGSYSCMCETGYRLAADQHRCEDVDDCILEPSPCPQRCVNTQGGFECHCYPNYD 356
+ GSY C C G+RL+ D CED+++C SPC Q C N G ++C+C Y
Sbjct: 416 ---ENTLGSYLCSCSVGFRLSVDGRSCEDINEC--SSSPCSQECANVYGSYQCYCRRGYQ 470
Query: 357 L--VDGECVEPVDPCFRANCEYQCQPLNQTSYLCVCAEGFAPIPHEPHRCQMFCNQTACP 414
L VDG E +D C + C SY C+ G
Sbjct: 471 LSDVDGVTCEDIDECALPTGGHIC------SYRCINIPG--------------------- 503
Query: 415 ADCDPNTQASCECPE-GYIL-DDGFICTDIDECENG-GFCS--GVCHNLPGTFECI 465
C CP GY L +G C DIDEC G CS C N+ G F C+
Sbjct: 504 -------SFQCSCPSSGYRLAPNGRNCQDIDECVTGIHNCSINETCFNIQGGFRCL 552
Score = 70.5 bits (171), Expect = 4e-12
Identities = 63/233 (27%), Positives = 94/233 (40%), Gaps = 34/233 (14%)
Query: 134 GPLCVAVSAAEATVPSEPIWEEQQCEVKADGFLCEFHFPATCRPLAVEPGAAAAAVSITY 193
G CV V E P+EP + +C F CE C+ G + V +
Sbjct: 351 GTRCVDVD--ECAPPAEPCGKGHRCVNSPGSFRCE------CKTGYYFDGISRMCVDVNE 402
Query: 194 GTPFAARGADFQA-LPVGSSAAVAPLGLQLMCTAPPGAVQGHWAREAPGAWDCSVENGGC 252
+ R + +GS +G +L +V G R +CS + C
Sbjct: 403 CQRYPGRLCGHKCENTLGSYLCSCSVGFRL-------SVDG---RSCEDINECS--SSPC 450
Query: 253 EHACNAIPGAPRCQCPAGAAL-QADGRSC---TASATQSCNDLCEHFCVPNPDQPGSYSC 308
C + G+ +C C G L DG +C A + +C + C+ + PGS+ C
Sbjct: 451 SQECANVYGSYQCYCRRGYQLSDVDGVTCEDIDECALPTGGHICSYRCI---NIPGSFQC 507
Query: 309 MC-ETGYRLAADQHRCEDVDDCILEPSPCP--QRCVNTQGGFEC---HCYPNY 355
C +GYRLA + C+D+D+C+ C + C N QGGF C C NY
Sbjct: 508 SCPSSGYRLAPNGRNCQDIDECVTGIHNCSINETCFNIQGGFRCLAFECPENY 560
Score = 69.7 bits (169), Expect = 7e-12
Identities = 58/212 (27%), Positives = 81/212 (38%), Gaps = 50/212 (23%)
Query: 292 CEHFCVPNPDQPGSYSCMCETGYRLAADQHRCEDVDDCILEPSPC--PQRCVNTQGGFEC 349
C+ C D+ C C GY+L +D CEDV++CI C + C+NT G F C
Sbjct: 186 CKQQCRDTGDE---VVCSCFVGYQLLSDGVSCEDVNECITGSHSCRLGESCINTVGSFRC 242
Query: 350 H----CYPNYDLVDGECVEPVDPCFRA--NC-----------EYQCQPLNQ--TSYL--- 387
C Y+L + + +D C NC ++C+P Q + ++
Sbjct: 243 QRDSSCGTGYELTEDNSCKDIDECESGIHNCLPDFICQNTLGSFRCRPKLQCKSGFIQDA 302
Query: 388 ---------CVCAEGFAPIPHEPHRCQMFCNQTACPADCDPNTQASCECPEGYIL-DDGF 437
C+ PI H C T C N C GY L ++G
Sbjct: 303 LGNCIDINECLSISAPCPIGHT-------CINTEGSYTCQKNVP---NCGRGYHLNEEGT 352
Query: 438 ICTDIDECENGGFCSGV---CHNLPGTFECIC 466
C D+DEC G C N PG+F C C
Sbjct: 353 RCVDVDECAPPAEPCGKGHRCVNSPGSFRCEC 384
Score = 54.3 bits (129), Expect = 3e-07
Identities = 54/209 (25%), Positives = 77/209 (36%), Gaps = 44/209 (21%)
Query: 267 CPAGAALQADGRSCTASAT--QSCNDLCEHFCVPNPDQPG-SYSCMCETGYRLAADQHRC 323
C G A QA G+SC S C + CV + + + ET + ++ +
Sbjct: 113 CLLGRAAQAQGQSCEYSLMVGYQCGQVFRACCVKSQETGDLDVGGLQETDKIIEVEEEQ- 171
Query: 324 ED--VDDCILEPSPCPQRCVNTQGGFECHCYPNYDLV-DGECVEPVDPCFRANCEYQCQP 380
ED ++D PC Q+C +T C C+ Y L+ DG E V+ C +
Sbjct: 172 EDPYLNDRCRGGGPCKQQCRDTGDEVVCSCFVGYQLLSDGVSCEDVNECITGS------- 224
Query: 381 LNQTSYLCVCAEGFAPIPHEPHRCQM--FCNQTACPADCDPNTQASCECPEGYILDDGFI 438
H C++ C T C Q C GY L +
Sbjct: 225 ---------------------HSCRLGESCINTVGSFRC----QRDSSCGTGYELTEDNS 259
Query: 439 CTDIDECENG---GFCSGVCHNLPGTFEC 464
C DIDECE+G +C N G+F C
Sbjct: 260 CKDIDECESGIHNCLPDFICQNTLGSFRC 288
>gi|34734066 fibulin 1 isoform D [Homo sapiens]
Length = 703
Score = 113 bits (282), Expect = 5e-25
Identities = 82/252 (32%), Positives = 113/252 (44%), Gaps = 30/252 (11%)
Query: 252 CEHACNAIPGAPRCQCPAGAALQADGRSCTASATQSCNDLCE--HFCVPNPDQPGSYSCM 309
C++ + P+ QC +G A G + S + C H C+ + GSY+C
Sbjct: 279 CQNTLGSFRCRPKLQCKSGFIQDALGNCIDINECLSISAPCPIGHTCI---NTEGSYTCQ 335
Query: 310 -----CETGYRLAADQHRCEDVDDCILEPSPCPQ--RCVNTQGGFECHCYPNY--DLVDG 360
C GY L + RC DVD+C PC + RCVN+ G F C C Y D +
Sbjct: 336 KNVPNCGRGYHLNEEGTRCVDVDECAPPAEPCGKGHRCVNSPGSFRCECKTGYYFDGISR 395
Query: 361 ECVEPVDPCFRAN---CEYQCQPLNQTSYLCVCAEGFAPIPHEPHRCQMF--CNQTACPA 415
CV+ V+ C R C ++C+ SYLC C+ GF + + C+ C+ + C
Sbjct: 396 MCVD-VNECQRYPGRLCGHKCEN-TLGSYLCSCSVGFR-LSVDGRSCEDINECSSSPCSQ 452
Query: 416 DCDPNTQAS--CECPEGYILDD--GFICTDIDECE---NGGFCSGVCHNLPGTFECICGP 468
+C N S C C GY L D G C DIDEC G CS C N+PG+F+C C
Sbjct: 453 EC-ANVYGSYQCYCRRGYQLSDVDGVTCEDIDECALPTGGHICSYRCINIPGSFQCSCPS 511
Query: 469 DSALARHIGTDC 480
G +C
Sbjct: 512 SGYRLAPNGRNC 523
Score = 100 bits (250), Expect = 3e-21
Identities = 75/236 (31%), Positives = 93/236 (39%), Gaps = 53/236 (22%)
Query: 239 APGAWDCSVENGGCEHACNAIPGAPRCQCPAGAALQADGRSCTA--SATQSCNDLCEHFC 296
AP A C G H C PG+ RC+C G R C + LC H C
Sbjct: 361 APPAEPC-----GKGHRCVNSPGSFRCECKTGYYFDGISRMCVDVNECQRYPGRLCGHKC 415
Query: 297 VPNPDQPGSYSCMCETGYRLAADQHRCEDVDDCILEPSPCPQRCVNTQGGFECHCYPNYD 356
+ GSY C C G+RL+ D CED+++C SPC Q C N G ++C+C Y
Sbjct: 416 ---ENTLGSYLCSCSVGFRLSVDGRSCEDINEC--SSSPCSQECANVYGSYQCYCRRGYQ 470
Query: 357 L--VDGECVEPVDPCFRANCEYQCQPLNQTSYLCVCAEGFAPIPHEPHRCQMFCNQTACP 414
L VDG E +D C + C SY C+ G
Sbjct: 471 LSDVDGVTCEDIDECALPTGGHIC------SYRCINIPG--------------------- 503
Query: 415 ADCDPNTQASCECPE-GYIL-DDGFICTDIDECENG-GFCS--GVCHNLPGTFECI 465
C CP GY L +G C DIDEC G CS C N+ G F C+
Sbjct: 504 -------SFQCSCPSSGYRLAPNGRNCQDIDECVTGIHNCSINETCFNIQGGFRCL 552
Score = 70.5 bits (171), Expect = 4e-12
Identities = 63/233 (27%), Positives = 94/233 (40%), Gaps = 34/233 (14%)
Query: 134 GPLCVAVSAAEATVPSEPIWEEQQCEVKADGFLCEFHFPATCRPLAVEPGAAAAAVSITY 193
G CV V E P+EP + +C F CE C+ G + V +
Sbjct: 351 GTRCVDVD--ECAPPAEPCGKGHRCVNSPGSFRCE------CKTGYYFDGISRMCVDVNE 402
Query: 194 GTPFAARGADFQA-LPVGSSAAVAPLGLQLMCTAPPGAVQGHWAREAPGAWDCSVENGGC 252
+ R + +GS +G +L +V G R +CS + C
Sbjct: 403 CQRYPGRLCGHKCENTLGSYLCSCSVGFRL-------SVDG---RSCEDINECS--SSPC 450
Query: 253 EHACNAIPGAPRCQCPAGAAL-QADGRSC---TASATQSCNDLCEHFCVPNPDQPGSYSC 308
C + G+ +C C G L DG +C A + +C + C+ + PGS+ C
Sbjct: 451 SQECANVYGSYQCYCRRGYQLSDVDGVTCEDIDECALPTGGHICSYRCI---NIPGSFQC 507
Query: 309 MC-ETGYRLAADQHRCEDVDDCILEPSPCP--QRCVNTQGGFEC---HCYPNY 355
C +GYRLA + C+D+D+C+ C + C N QGGF C C NY
Sbjct: 508 SCPSSGYRLAPNGRNCQDIDECVTGIHNCSINETCFNIQGGFRCLAFECPENY 560
Score = 69.7 bits (169), Expect = 7e-12
Identities = 58/212 (27%), Positives = 81/212 (38%), Gaps = 50/212 (23%)
Query: 292 CEHFCVPNPDQPGSYSCMCETGYRLAADQHRCEDVDDCILEPSPC--PQRCVNTQGGFEC 349
C+ C D+ C C GY+L +D CEDV++CI C + C+NT G F C
Sbjct: 186 CKQQCRDTGDE---VVCSCFVGYQLLSDGVSCEDVNECITGSHSCRLGESCINTVGSFRC 242
Query: 350 H----CYPNYDLVDGECVEPVDPCFRA--NC-----------EYQCQPLNQ--TSYL--- 387
C Y+L + + +D C NC ++C+P Q + ++
Sbjct: 243 QRDSSCGTGYELTEDNSCKDIDECESGIHNCLPDFICQNTLGSFRCRPKLQCKSGFIQDA 302
Query: 388 ---------CVCAEGFAPIPHEPHRCQMFCNQTACPADCDPNTQASCECPEGYIL-DDGF 437
C+ PI H C T C N C GY L ++G
Sbjct: 303 LGNCIDINECLSISAPCPIGHT-------CINTEGSYTCQKNVP---NCGRGYHLNEEGT 352
Query: 438 ICTDIDECENGGFCSGV---CHNLPGTFECIC 466
C D+DEC G C N PG+F C C
Sbjct: 353 RCVDVDECAPPAEPCGKGHRCVNSPGSFRCEC 384
Score = 54.3 bits (129), Expect = 3e-07
Identities = 54/209 (25%), Positives = 77/209 (36%), Gaps = 44/209 (21%)
Query: 267 CPAGAALQADGRSCTASAT--QSCNDLCEHFCVPNPDQPG-SYSCMCETGYRLAADQHRC 323
C G A QA G+SC S C + CV + + + ET + ++ +
Sbjct: 113 CLLGRAAQAQGQSCEYSLMVGYQCGQVFRACCVKSQETGDLDVGGLQETDKIIEVEEEQ- 171
Query: 324 ED--VDDCILEPSPCPQRCVNTQGGFECHCYPNYDLV-DGECVEPVDPCFRANCEYQCQP 380
ED ++D PC Q+C +T C C+ Y L+ DG E V+ C +
Sbjct: 172 EDPYLNDRCRGGGPCKQQCRDTGDEVVCSCFVGYQLLSDGVSCEDVNECITGS------- 224
Query: 381 LNQTSYLCVCAEGFAPIPHEPHRCQM--FCNQTACPADCDPNTQASCECPEGYILDDGFI 438
H C++ C T C Q C GY L +
Sbjct: 225 ---------------------HSCRLGESCINTVGSFRC----QRDSSCGTGYELTEDNS 259
Query: 439 CTDIDECENG---GFCSGVCHNLPGTFEC 464
C DIDECE+G +C N G+F C
Sbjct: 260 CKDIDECESGIHNCLPDFICQNTLGSFRC 288
>gi|34734062 fibulin 1 isoform C precursor [Homo sapiens]
Length = 683
Score = 113 bits (282), Expect = 5e-25
Identities = 82/252 (32%), Positives = 113/252 (44%), Gaps = 30/252 (11%)
Query: 252 CEHACNAIPGAPRCQCPAGAALQADGRSCTASATQSCNDLCE--HFCVPNPDQPGSYSCM 309
C++ + P+ QC +G A G + S + C H C+ + GSY+C
Sbjct: 279 CQNTLGSFRCRPKLQCKSGFIQDALGNCIDINECLSISAPCPIGHTCI---NTEGSYTCQ 335
Query: 310 -----CETGYRLAADQHRCEDVDDCILEPSPCPQ--RCVNTQGGFECHCYPNY--DLVDG 360
C GY L + RC DVD+C PC + RCVN+ G F C C Y D +
Sbjct: 336 KNVPNCGRGYHLNEEGTRCVDVDECAPPAEPCGKGHRCVNSPGSFRCECKTGYYFDGISR 395
Query: 361 ECVEPVDPCFRAN---CEYQCQPLNQTSYLCVCAEGFAPIPHEPHRCQMF--CNQTACPA 415
CV+ V+ C R C ++C+ SYLC C+ GF + + C+ C+ + C
Sbjct: 396 MCVD-VNECQRYPGRLCGHKCEN-TLGSYLCSCSVGFR-LSVDGRSCEDINECSSSPCSQ 452
Query: 416 DCDPNTQAS--CECPEGYILDD--GFICTDIDECE---NGGFCSGVCHNLPGTFECICGP 468
+C N S C C GY L D G C DIDEC G CS C N+PG+F+C C
Sbjct: 453 EC-ANVYGSYQCYCRRGYQLSDVDGVTCEDIDECALPTGGHICSYRCINIPGSFQCSCPS 511
Query: 469 DSALARHIGTDC 480
G +C
Sbjct: 512 SGYRLAPNGRNC 523
Score = 100 bits (250), Expect = 3e-21
Identities = 75/236 (31%), Positives = 93/236 (39%), Gaps = 53/236 (22%)
Query: 239 APGAWDCSVENGGCEHACNAIPGAPRCQCPAGAALQADGRSCTA--SATQSCNDLCEHFC 296
AP A C G H C PG+ RC+C G R C + LC H C
Sbjct: 361 APPAEPC-----GKGHRCVNSPGSFRCECKTGYYFDGISRMCVDVNECQRYPGRLCGHKC 415
Query: 297 VPNPDQPGSYSCMCETGYRLAADQHRCEDVDDCILEPSPCPQRCVNTQGGFECHCYPNYD 356
+ GSY C C G+RL+ D CED+++C SPC Q C N G ++C+C Y
Sbjct: 416 ---ENTLGSYLCSCSVGFRLSVDGRSCEDINEC--SSSPCSQECANVYGSYQCYCRRGYQ 470
Query: 357 L--VDGECVEPVDPCFRANCEYQCQPLNQTSYLCVCAEGFAPIPHEPHRCQMFCNQTACP 414
L VDG E +D C + C SY C+ G
Sbjct: 471 LSDVDGVTCEDIDECALPTGGHIC------SYRCINIPG--------------------- 503
Query: 415 ADCDPNTQASCECPE-GYIL-DDGFICTDIDECENG-GFCS--GVCHNLPGTFECI 465
C CP GY L +G C DIDEC G CS C N+ G F C+
Sbjct: 504 -------SFQCSCPSSGYRLAPNGRNCQDIDECVTGIHNCSINETCFNIQGGFRCL 552
Score = 70.9 bits (172), Expect = 3e-12
Identities = 72/264 (27%), Positives = 104/264 (39%), Gaps = 36/264 (13%)
Query: 134 GPLCVAVSAAEATVPSEPIWEEQQCEVKADGFLCEFHFPATCRPLAVEPGAAAAAVSITY 193
G CV V E P+EP + +C F CE C+ G + V +
Sbjct: 351 GTRCVDVD--ECAPPAEPCGKGHRCVNSPGSFRCE------CKTGYYFDGISRMCVDVNE 402
Query: 194 GTPFAARGADFQA-LPVGSSAAVAPLGLQLMCTAPPGAVQGHWAREAPGAWDCSVENGGC 252
+ R + +GS +G +L +V G R +CS + C
Sbjct: 403 CQRYPGRLCGHKCENTLGSYLCSCSVGFRL-------SVDG---RSCEDINECS--SSPC 450
Query: 253 EHACNAIPGAPRCQCPAGAAL-QADGRSC---TASATQSCNDLCEHFCVPNPDQPGSYSC 308
C + G+ +C C G L DG +C A + +C + C+ + PGS+ C
Sbjct: 451 SQECANVYGSYQCYCRRGYQLSDVDGVTCEDIDECALPTGGHICSYRCI---NIPGSFQC 507
Query: 309 MC-ETGYRLAADQHRCEDVDDCILEPSPCP--QRCVNTQGGFEC---HCYPNYDLVDGEC 362
C +GYRLA + C+D+D+C+ C + C N QGGF C C NY
Sbjct: 508 SCPSSGYRLAPNGRNCQDIDECVTGIHNCSINETCFNIQGGFRCLAFECPENYRRSAATR 567
Query: 363 VEPVDPCFRANCEYQCQPLNQTSY 386
E + PC N E PL T Y
Sbjct: 568 CERL-PC-HENRECSKLPLRITYY 589
Score = 69.7 bits (169), Expect = 7e-12
Identities = 58/212 (27%), Positives = 81/212 (38%), Gaps = 50/212 (23%)
Query: 292 CEHFCVPNPDQPGSYSCMCETGYRLAADQHRCEDVDDCILEPSPC--PQRCVNTQGGFEC 349
C+ C D+ C C GY+L +D CEDV++CI C + C+NT G F C
Sbjct: 186 CKQQCRDTGDE---VVCSCFVGYQLLSDGVSCEDVNECITGSHSCRLGESCINTVGSFRC 242
Query: 350 H----CYPNYDLVDGECVEPVDPCFRA--NC-----------EYQCQPLNQ--TSYL--- 387
C Y+L + + +D C NC ++C+P Q + ++
Sbjct: 243 QRDSSCGTGYELTEDNSCKDIDECESGIHNCLPDFICQNTLGSFRCRPKLQCKSGFIQDA 302
Query: 388 ---------CVCAEGFAPIPHEPHRCQMFCNQTACPADCDPNTQASCECPEGYIL-DDGF 437
C+ PI H C T C N C GY L ++G
Sbjct: 303 LGNCIDINECLSISAPCPIGHT-------CINTEGSYTCQKNVP---NCGRGYHLNEEGT 352
Query: 438 ICTDIDECENGGFCSGV---CHNLPGTFECIC 466
C D+DEC G C N PG+F C C
Sbjct: 353 RCVDVDECAPPAEPCGKGHRCVNSPGSFRCEC 384
Score = 54.3 bits (129), Expect = 3e-07
Identities = 54/209 (25%), Positives = 77/209 (36%), Gaps = 44/209 (21%)
Query: 267 CPAGAALQADGRSCTASAT--QSCNDLCEHFCVPNPDQPG-SYSCMCETGYRLAADQHRC 323
C G A QA G+SC S C + CV + + + ET + ++ +
Sbjct: 113 CLLGRAAQAQGQSCEYSLMVGYQCGQVFRACCVKSQETGDLDVGGLQETDKIIEVEEEQ- 171
Query: 324 ED--VDDCILEPSPCPQRCVNTQGGFECHCYPNYDLV-DGECVEPVDPCFRANCEYQCQP 380
ED ++D PC Q+C +T C C+ Y L+ DG E V+ C +
Sbjct: 172 EDPYLNDRCRGGGPCKQQCRDTGDEVVCSCFVGYQLLSDGVSCEDVNECITGS------- 224
Query: 381 LNQTSYLCVCAEGFAPIPHEPHRCQM--FCNQTACPADCDPNTQASCECPEGYILDDGFI 438
H C++ C T C Q C GY L +
Sbjct: 225 ---------------------HSCRLGESCINTVGSFRC----QRDSSCGTGYELTEDNS 259
Query: 439 CTDIDECENG---GFCSGVCHNLPGTFEC 464
C DIDECE+G +C N G+F C
Sbjct: 260 CKDIDECESGIHNCLPDFICQNTLGSFRC 288
>gi|46249414 latent transforming growth factor beta binding protein 1
isoform LTBP-1L [Homo sapiens]
Length = 1722
Score = 112 bits (279), Expect = 1e-24
Identities = 78/261 (29%), Positives = 119/261 (45%), Gaps = 17/261 (6%)
Query: 223 MCTAPPGAVQGHWAREAPGAWDCSVENGGCEHACNAIPGAPRCQCPAGAALQADGRSCTA 282
MC+ G + + +C N C G+ RC C G L A C
Sbjct: 1062 MCSCHKGYTRTPDHKHCRDIDECQQGNLCVNGQCKNTEGSFRCTCGQGYQLSAAKDQCED 1121
Query: 283 SATQSCNDLCEHFCVPNPDQPGSYSCMCETGYRLAADQHRCEDVDDCILEPSPCPQR-CV 341
LC H N + GS+ C+C+ GYR + CED+++C+ + S C + C+
Sbjct: 1122 IDECQHRHLCAHGQCRNTE--GSFQCVCDQGYRASGLGDHCEDINECLEDKSVCQRGDCI 1179
Query: 342 NTQGGFECHCYPNYDLVDGECVEPVDPCFRAN-CEYQCQPLN-QTSYLCVCAEGFAPIPH 399
NT G ++C C + L D + + ++ C C Q + LN + S+ CVC +GF+ I
Sbjct: 1180 NTAGSYDCTCPDGFQLDDNKTCQDINECEHPGLCGPQGECLNTEGSFHCVCQQGFS-ISA 1238
Query: 400 EPHRCQMF---CNQTACPAD--CDPNTQAS--CECPEGYIL-DDGFICTDIDECEN-GGF 450
+ C+ N T C + CD NT S C C +G+ DG C D++ECE G
Sbjct: 1239 DGRTCEDIDECVNNTVCDSHGFCD-NTAGSFRCLCYQGFQAPQDGQGCVDVNECELLSGV 1297
Query: 451 CS-GVCHNLPGTFECICGPDS 470
C C N+ G+F C+C ++
Sbjct: 1298 CGEAFCENVEGSFLCVCADEN 1318
Score = 111 bits (278), Expect = 2e-24
Identities = 83/270 (30%), Positives = 115/270 (42%), Gaps = 38/270 (14%)
Query: 224 CTAPPGAVQGHWAREAPGAW--------DCSVENGGCEHACNAIPGAPRCQCPAGAALQA 275
C PG+ Q E W +C N C+ + G+ C C G
Sbjct: 1014 CVNSPGSYQCVPCTEGFRGWNGQCLDVDECLEPNVCANGDCSNLEGSYMCSCHKGYTRTP 1073
Query: 276 DGRSCTASATQSCNDLCEHFCVPNPDQPGSYSCMCETGYRLAADQHRCEDVDDCILEPSP 335
D + C +LC + N + GS+ C C GY+L+A + +CED+D+C
Sbjct: 1074 DHKHCRDIDECQQGNLCVNGQCKNTE--GSFRCTCGQGYQLSAAKDQCEDIDECQHRHLC 1131
Query: 336 CPQRCVNTQGGFECHCYPNY---DLVD-----GECVEPVDPCFRANCEYQCQPLNQT-SY 386
+C NT+G F+C C Y L D EC+E C R +C +N SY
Sbjct: 1132 AHGQCRNTEGSFQCVCDQGYRASGLGDHCEDINECLEDKSVCQRGDC------INTAGSY 1185
Query: 387 LCVCAEGFAPIPHEPHRCQMFCNQTACPADCDP-----NTQAS--CECPEGYILD-DGFI 438
C C +GF ++ CQ N+ P C P NT+ S C C +G+ + DG
Sbjct: 1186 DCTCPDGFQLDDNKT--CQDI-NECEHPGLCGPQGECLNTEGSFHCVCQQGFSISADGRT 1242
Query: 439 CTDIDECENGGFCS--GVCHNLPGTFECIC 466
C DIDEC N C G C N G+F C+C
Sbjct: 1243 CEDIDECVNNTVCDSHGFCDNTAGSFRCLC 1272
Score = 95.9 bits (237), Expect = 9e-20
Identities = 74/236 (31%), Positives = 98/236 (41%), Gaps = 17/236 (7%)
Query: 244 DCSVENGGCEHA-CNAIPGAPRCQCPAGAALQADGRSCTASATQSCNDLCEHFCVPN--P 300
+C+V C C +P C C G R C C + +H C
Sbjct: 877 ECTVNPDICGAGHCINLPVRYTCICYEGYRFSEQQRKCVD--IDECTQV-QHLCSQGRCE 933
Query: 301 DQPGSYSCMCETGYRLAADQHRCEDVDDCILEPSPCPQ-RCVNTQGGFEC-HCYPNYDLV 358
+ GS+ C+C G+ + + C DVD+C L P C + CVNT G F C +C Y +
Sbjct: 934 NTEGSFLCICPAGFMASEEGTNCIDVDEC-LRPDVCGEGHCVNTVGAFRCEYCDSGYRMT 992
Query: 359 DGECVEPVDPCFRANCEYQCQPLNQT-SYLCV-CAEGFAPIPHEPHRCQMFCNQTACP-A 415
E +D C + Q +N SY CV C EGF + C
Sbjct: 993 QRGRCEDIDECLNPSTCPDEQCVNSPGSYQCVPCTEGFRGWNGQCLDVDECLEPNVCANG 1052
Query: 416 DCDPNTQAS--CECPEGYI-LDDGFICTDIDECENGGFC-SGVCHNLPGTFECICG 467
DC N + S C C +GY D C DIDEC+ G C +G C N G+F C CG
Sbjct: 1053 DCS-NLEGSYMCSCHKGYTRTPDHKHCRDIDECQQGNLCVNGQCKNTEGSFRCTCG 1107
Score = 78.2 bits (191), Expect = 2e-14
Identities = 62/211 (29%), Positives = 95/211 (45%), Gaps = 24/211 (11%)
Query: 244 DCSVENGGCEHA-CNAIPGAPRCQCPAGAALQADGRSCTASATQSCNDLCEH--FCVPNP 300
+C + C+ C G+ C CP G L D ++C Q N+ CEH C P
Sbjct: 1165 ECLEDKSVCQRGDCINTAGSYDCTCPDGFQLD-DNKTC-----QDINE-CEHPGLCGPQG 1217
Query: 301 D---QPGSYSCMCETGYRLAADQHRCEDVDDCILEPSPCPQR--CVNTQGGFECHCYPNY 355
+ GS+ C+C+ G+ ++AD CED+D+C+ + C C NT G F C CY +
Sbjct: 1218 ECLNTEGSFHCVCQQGFSISADGRTCEDIDECV-NNTVCDSHGFCDNTAGSFRCLCYQGF 1276
Query: 356 DL-VDGECVEPVDPC--FRANC-EYQCQPLNQTSYLCVCAEGFAPIPHEPHRCQMFCNQT 411
DG+ V+ C C E C+ + + S+LCVCA+ +C+ T
Sbjct: 1277 QAPQDGQGCVDVNECELLSGVCGEAFCENV-EGSFLCVCADENQEYSPMTGQCRS-RTST 1334
Query: 412 ACPADCDPNTQASCECPEGYILDDGFICTDI 442
D D + EC Y L+D +C ++
Sbjct: 1335 DLDVDVDQPKEEKKEC--YYNLNDASLCDNV 1363
Score = 74.3 bits (181), Expect = 3e-13
Identities = 74/316 (23%), Positives = 112/316 (35%), Gaps = 94/316 (29%)
Query: 241 GAWDCSVENG-------------GCEHA--------CNAIPGAPRCQCPAGAALQADGRS 279
G++DC+ +G CEH C G+ C C G ++ ADGR+
Sbjct: 1183 GSYDCTCPDGFQLDDNKTCQDINECEHPGLCGPQGECLNTEGSFHCVCQQGFSISADGRT 1242
Query: 280 CTASATQSCNDLCEH--FCVPNPDQPGSYSCMCETGYRLAADQHRCEDVDDCILEPSPCP 337
C N +C+ FC + GS+ C+C G++ D C DV++C L C
Sbjct: 1243 CEDIDECVNNTVCDSHGFC---DNTAGSFRCLCYQGFQAPQDGQGCVDVNECELLSGVCG 1299
Query: 338 QR-CVNTQGGFECHCYPN---YDLVDGEC------------------------------- 362
+ C N +G F C C Y + G+C
Sbjct: 1300 EAFCENVEGSFLCVCADENQEYSPMTGQCRSRTSTDLDVDVDQPKEEKKECYYNLNDASL 1359
Query: 363 --------VEPVDPCFRA------NCE-YQCQPLNQTSYLCVCAEGFAPIP--------- 398
V + C + NCE + C L + +C +G +P
Sbjct: 1360 CDNVLAPNVTKQECCCTSGAGWGDNCEIFPCPVLGTAEFTEMCPKGKGFVPAGESSSEAG 1419
Query: 399 ----HEPHRCQMFCNQTACPADCDPNTQAS--CECPEGYILDDGFI-CTDIDECENGGFC 451
+ C +F Q C NT+ C C +G D + C D+DEC++ C
Sbjct: 1420 GENYKDADECLLF-GQEICKNGFCLNTRPGYECYCKQGTYYDPVKLQCFDMDECQDPSSC 1478
Query: 452 -SGVCHNLPGTFECIC 466
G C N G++ C C
Sbjct: 1479 IDGQCVNTEGSYNCFC 1494
Score = 49.3 bits (116), Expect = 1e-05
Identities = 47/161 (29%), Positives = 72/161 (44%), Gaps = 36/161 (22%)
Query: 267 CPAGAALQADGRSCTASATQSCND----------LCEH-FCVPNPDQPGSYSCMCETGYR 315
CP G G S + + ++ D +C++ FC+ +PG Y C C+ G
Sbjct: 1402 CPKGKGFVPAGESSSEAGGENYKDADECLLFGQEICKNGFCLNT--RPG-YECYCKQGTY 1458
Query: 316 LAADQHRCEDVDDCILEPSPCPQ-RCVNTQGGFECHC-YPN-YDLVDGECVEPV------ 366
+ +C D+D+C +PS C +CVNT+G + C C +P D + C+ P
Sbjct: 1459 YDPVKLQCFDMDEC-QDPSSCIDGQCVNTEGSYNCFCTHPMVLDASEKRCIRPAESNEQI 1517
Query: 367 -------DPCF-RANCEYQC-QPL--NQTSYL-CVCAEGFA 395
D C+ + EY C +PL QT+Y C C G A
Sbjct: 1518 EETDVYQDLCWEHLSDEYVCSRPLVGKQTTYTECCCLYGEA 1558
Score = 45.4 bits (106), Expect = 1e-04
Identities = 46/151 (30%), Positives = 62/151 (41%), Gaps = 31/151 (20%)
Query: 296 CVPNPDQPGSYSCM-CETGYRLAADQHRCEDVDDCILEPSPCPQ-RCVNTQGGFECHCYP 353
C P G M C GY+ + C+D+++C L+ CP C+NT G + C C
Sbjct: 597 CPKKPSYHGYNQMMECLPGYKRVNNTF-CQDINECQLQ-GVCPNGECLNTMGSYRCTCKI 654
Query: 354 NY--DLVDGECV-------EPVDPCFR-ANCEYQCQ---PLNQTSYLCVCAEGFAPIPHE 400
+ D CV E PC+R + QC ++ T LC C+ G A PH
Sbjct: 655 GFGPDPTFSSCVPDPPVISEEKGPCYRLVSSGRQCMHPLSVHLTKQLCCCSVGKAWGPH- 713
Query: 401 PHRCQMFCNQTACPADCDPNTQASCE-CPEG 430
C+ CP P T A E CP G
Sbjct: 714 ---CE------KCPL---PGTAAFKEICPGG 732
Score = 42.0 bits (97), Expect = 0.002
Identities = 20/54 (37%), Positives = 28/54 (51%), Gaps = 4/54 (7%)
Query: 306 YSCMCETGYRLAADQHRCEDVDDCIL---EPSPCPQ-RCVNTQGGFECHCYPNY 355
Y+C C GY L + C DV++C S C +C+NT G ++C C P Y
Sbjct: 1644 YTCDCFDGYHLDTAKMTCVDVNECDELNNRMSLCKNAKCINTDGSYKCLCLPGY 1697
Score = 39.7 bits (91), Expect = 0.008
Identities = 20/49 (40%), Positives = 26/49 (53%), Gaps = 5/49 (10%)
Query: 426 ECPEGYILDDGFICTDIDECENGGFC-SGVCHNLPGTFECIC----GPD 469
EC GY + C DI+EC+ G C +G C N G++ C C GPD
Sbjct: 611 ECLPGYKRVNNTFCQDINECQLQGVCPNGECLNTMGSYRCTCKIGFGPD 659
Score = 36.6 bits (83), Expect = 0.064
Identities = 17/51 (33%), Positives = 27/51 (52%), Gaps = 6/51 (11%)
Query: 424 SCECPEGYILDDG-FICTDIDECEN----GGFCSGV-CHNLPGTFECICGP 468
+C+C +GY LD C D++EC+ C C N G+++C+C P
Sbjct: 1645 TCDCFDGYHLDTAKMTCVDVNECDELNNRMSLCKNAKCINTDGSYKCLCLP 1695
Score = 35.8 bits (81), Expect = 0.11
Identities = 23/73 (31%), Positives = 32/73 (43%), Gaps = 9/73 (12%)
Query: 339 RCVNTQGGFECHCYPNY--DLVDGECVEPVDPCFRAN-----CEYQCQPLNQTSYLCVCA 391
RCV Q G+ C C+ Y D CV+ V+ C N C+ SY C+C
Sbjct: 1636 RCVRVQEGYTCDCFDGYHLDTAKMTCVD-VNECDELNNRMSLCKNAKCINTDGSYKCLCL 1694
Query: 392 EGFAPIPHEPHRC 404
G+ P +P+ C
Sbjct: 1695 PGYVP-SDKPNYC 1706
Score = 31.2 bits (69), Expect = 2.7
Identities = 24/80 (30%), Positives = 34/80 (42%), Gaps = 12/80 (15%)
Query: 242 AWDCSVENGGCEHA-CNAIPGAPRCQCPAGAALQADGRSCTASATQSCNDL------CEH 294
A +C + NG CE+ C + C C G L +C C++L C++
Sbjct: 1623 AEECGILNG-CENGRCVRVQEGYTCDCFDGYHLDTAKMTCVD--VNECDELNNRMSLCKN 1679
Query: 295 FCVPNPDQPGSYSCMCETGY 314
N D GSY C+C GY
Sbjct: 1680 AKCINTD--GSYKCLCLPGY 1697
>gi|46249412 latent transforming growth factor beta binding protein
1 isoform LTBP-1S [Homo sapiens]
Length = 1396
Score = 112 bits (279), Expect = 1e-24
Identities = 78/261 (29%), Positives = 119/261 (45%), Gaps = 17/261 (6%)
Query: 223 MCTAPPGAVQGHWAREAPGAWDCSVENGGCEHACNAIPGAPRCQCPAGAALQADGRSCTA 282
MC+ G + + +C N C G+ RC C G L A C
Sbjct: 736 MCSCHKGYTRTPDHKHCRDIDECQQGNLCVNGQCKNTEGSFRCTCGQGYQLSAAKDQCED 795
Query: 283 SATQSCNDLCEHFCVPNPDQPGSYSCMCETGYRLAADQHRCEDVDDCILEPSPCPQR-CV 341
LC H N + GS+ C+C+ GYR + CED+++C+ + S C + C+
Sbjct: 796 IDECQHRHLCAHGQCRNTE--GSFQCVCDQGYRASGLGDHCEDINECLEDKSVCQRGDCI 853
Query: 342 NTQGGFECHCYPNYDLVDGECVEPVDPCFRAN-CEYQCQPLN-QTSYLCVCAEGFAPIPH 399
NT G ++C C + L D + + ++ C C Q + LN + S+ CVC +GF+ I
Sbjct: 854 NTAGSYDCTCPDGFQLDDNKTCQDINECEHPGLCGPQGECLNTEGSFHCVCQQGFS-ISA 912
Query: 400 EPHRCQMF---CNQTACPAD--CDPNTQAS--CECPEGYIL-DDGFICTDIDECEN-GGF 450
+ C+ N T C + CD NT S C C +G+ DG C D++ECE G
Sbjct: 913 DGRTCEDIDECVNNTVCDSHGFCD-NTAGSFRCLCYQGFQAPQDGQGCVDVNECELLSGV 971
Query: 451 CS-GVCHNLPGTFECICGPDS 470
C C N+ G+F C+C ++
Sbjct: 972 CGEAFCENVEGSFLCVCADEN 992
Score = 111 bits (278), Expect = 2e-24
Identities = 83/270 (30%), Positives = 115/270 (42%), Gaps = 38/270 (14%)
Query: 224 CTAPPGAVQGHWAREAPGAW--------DCSVENGGCEHACNAIPGAPRCQCPAGAALQA 275
C PG+ Q E W +C N C+ + G+ C C G
Sbjct: 688 CVNSPGSYQCVPCTEGFRGWNGQCLDVDECLEPNVCANGDCSNLEGSYMCSCHKGYTRTP 747
Query: 276 DGRSCTASATQSCNDLCEHFCVPNPDQPGSYSCMCETGYRLAADQHRCEDVDDCILEPSP 335
D + C +LC + N + GS+ C C GY+L+A + +CED+D+C
Sbjct: 748 DHKHCRDIDECQQGNLCVNGQCKNTE--GSFRCTCGQGYQLSAAKDQCEDIDECQHRHLC 805
Query: 336 CPQRCVNTQGGFECHCYPNY---DLVD-----GECVEPVDPCFRANCEYQCQPLNQT-SY 386
+C NT+G F+C C Y L D EC+E C R +C +N SY
Sbjct: 806 AHGQCRNTEGSFQCVCDQGYRASGLGDHCEDINECLEDKSVCQRGDC------INTAGSY 859
Query: 387 LCVCAEGFAPIPHEPHRCQMFCNQTACPADCDP-----NTQAS--CECPEGYILD-DGFI 438
C C +GF ++ CQ N+ P C P NT+ S C C +G+ + DG
Sbjct: 860 DCTCPDGFQLDDNKT--CQDI-NECEHPGLCGPQGECLNTEGSFHCVCQQGFSISADGRT 916
Query: 439 CTDIDECENGGFCS--GVCHNLPGTFECIC 466
C DIDEC N C G C N G+F C+C
Sbjct: 917 CEDIDECVNNTVCDSHGFCDNTAGSFRCLC 946
Score = 95.9 bits (237), Expect = 9e-20
Identities = 74/236 (31%), Positives = 98/236 (41%), Gaps = 17/236 (7%)
Query: 244 DCSVENGGCEHA-CNAIPGAPRCQCPAGAALQADGRSCTASATQSCNDLCEHFCVPN--P 300
+C+V C C +P C C G R C C + +H C
Sbjct: 551 ECTVNPDICGAGHCINLPVRYTCICYEGYRFSEQQRKCVD--IDECTQV-QHLCSQGRCE 607
Query: 301 DQPGSYSCMCETGYRLAADQHRCEDVDDCILEPSPCPQ-RCVNTQGGFEC-HCYPNYDLV 358
+ GS+ C+C G+ + + C DVD+C L P C + CVNT G F C +C Y +
Sbjct: 608 NTEGSFLCICPAGFMASEEGTNCIDVDEC-LRPDVCGEGHCVNTVGAFRCEYCDSGYRMT 666
Query: 359 DGECVEPVDPCFRANCEYQCQPLNQT-SYLCV-CAEGFAPIPHEPHRCQMFCNQTACP-A 415
E +D C + Q +N SY CV C EGF + C
Sbjct: 667 QRGRCEDIDECLNPSTCPDEQCVNSPGSYQCVPCTEGFRGWNGQCLDVDECLEPNVCANG 726
Query: 416 DCDPNTQAS--CECPEGYI-LDDGFICTDIDECENGGFC-SGVCHNLPGTFECICG 467
DC N + S C C +GY D C DIDEC+ G C +G C N G+F C CG
Sbjct: 727 DCS-NLEGSYMCSCHKGYTRTPDHKHCRDIDECQQGNLCVNGQCKNTEGSFRCTCG 781
Score = 78.2 bits (191), Expect = 2e-14
Identities = 62/211 (29%), Positives = 95/211 (45%), Gaps = 24/211 (11%)
Query: 244 DCSVENGGCEHA-CNAIPGAPRCQCPAGAALQADGRSCTASATQSCNDLCEH--FCVPNP 300
+C + C+ C G+ C CP G L D ++C Q N+ CEH C P
Sbjct: 839 ECLEDKSVCQRGDCINTAGSYDCTCPDGFQLD-DNKTC-----QDINE-CEHPGLCGPQG 891
Query: 301 D---QPGSYSCMCETGYRLAADQHRCEDVDDCILEPSPCPQR--CVNTQGGFECHCYPNY 355
+ GS+ C+C+ G+ ++AD CED+D+C+ + C C NT G F C CY +
Sbjct: 892 ECLNTEGSFHCVCQQGFSISADGRTCEDIDECV-NNTVCDSHGFCDNTAGSFRCLCYQGF 950
Query: 356 DL-VDGECVEPVDPC--FRANC-EYQCQPLNQTSYLCVCAEGFAPIPHEPHRCQMFCNQT 411
DG+ V+ C C E C+ + + S+LCVCA+ +C+ T
Sbjct: 951 QAPQDGQGCVDVNECELLSGVCGEAFCENV-EGSFLCVCADENQEYSPMTGQCRS-RTST 1008
Query: 412 ACPADCDPNTQASCECPEGYILDDGFICTDI 442
D D + EC Y L+D +C ++
Sbjct: 1009 DLDVDVDQPKEEKKEC--YYNLNDASLCDNV 1037
Score = 74.3 bits (181), Expect = 3e-13
Identities = 74/316 (23%), Positives = 112/316 (35%), Gaps = 94/316 (29%)
Query: 241 GAWDCSVENG-------------GCEHA--------CNAIPGAPRCQCPAGAALQADGRS 279
G++DC+ +G CEH C G+ C C G ++ ADGR+
Sbjct: 857 GSYDCTCPDGFQLDDNKTCQDINECEHPGLCGPQGECLNTEGSFHCVCQQGFSISADGRT 916
Query: 280 CTASATQSCNDLCEH--FCVPNPDQPGSYSCMCETGYRLAADQHRCEDVDDCILEPSPCP 337
C N +C+ FC + GS+ C+C G++ D C DV++C L C
Sbjct: 917 CEDIDECVNNTVCDSHGFC---DNTAGSFRCLCYQGFQAPQDGQGCVDVNECELLSGVCG 973
Query: 338 QR-CVNTQGGFECHCYPN---YDLVDGEC------------------------------- 362
+ C N +G F C C Y + G+C
Sbjct: 974 EAFCENVEGSFLCVCADENQEYSPMTGQCRSRTSTDLDVDVDQPKEEKKECYYNLNDASL 1033
Query: 363 --------VEPVDPCFRA------NCE-YQCQPLNQTSYLCVCAEGFAPIP--------- 398
V + C + NCE + C L + +C +G +P
Sbjct: 1034 CDNVLAPNVTKQECCCTSGAGWGDNCEIFPCPVLGTAEFTEMCPKGKGFVPAGESSSEAG 1093
Query: 399 ----HEPHRCQMFCNQTACPADCDPNTQAS--CECPEGYILDDGFI-CTDIDECENGGFC 451
+ C +F Q C NT+ C C +G D + C D+DEC++ C
Sbjct: 1094 GENYKDADECLLF-GQEICKNGFCLNTRPGYECYCKQGTYYDPVKLQCFDMDECQDPSSC 1152
Query: 452 -SGVCHNLPGTFECIC 466
G C N G++ C C
Sbjct: 1153 IDGQCVNTEGSYNCFC 1168
Score = 49.3 bits (116), Expect = 1e-05
Identities = 47/161 (29%), Positives = 72/161 (44%), Gaps = 36/161 (22%)
Query: 267 CPAGAALQADGRSCTASATQSCND----------LCEH-FCVPNPDQPGSYSCMCETGYR 315
CP G G S + + ++ D +C++ FC+ +PG Y C C+ G
Sbjct: 1076 CPKGKGFVPAGESSSEAGGENYKDADECLLFGQEICKNGFCLNT--RPG-YECYCKQGTY 1132
Query: 316 LAADQHRCEDVDDCILEPSPCPQ-RCVNTQGGFECHC-YPN-YDLVDGECVEPV------ 366
+ +C D+D+C +PS C +CVNT+G + C C +P D + C+ P
Sbjct: 1133 YDPVKLQCFDMDEC-QDPSSCIDGQCVNTEGSYNCFCTHPMVLDASEKRCIRPAESNEQI 1191
Query: 367 -------DPCF-RANCEYQC-QPL--NQTSYL-CVCAEGFA 395
D C+ + EY C +PL QT+Y C C G A
Sbjct: 1192 EETDVYQDLCWEHLSDEYVCSRPLVGKQTTYTECCCLYGEA 1232
Score = 45.4 bits (106), Expect = 1e-04
Identities = 46/151 (30%), Positives = 62/151 (41%), Gaps = 31/151 (20%)
Query: 296 CVPNPDQPGSYSCM-CETGYRLAADQHRCEDVDDCILEPSPCPQ-RCVNTQGGFECHCYP 353
C P G M C GY+ + C+D+++C L+ CP C+NT G + C C
Sbjct: 271 CPKKPSYHGYNQMMECLPGYKRVNNTF-CQDINECQLQ-GVCPNGECLNTMGSYRCTCKI 328
Query: 354 NY--DLVDGECV-------EPVDPCFR-ANCEYQCQ---PLNQTSYLCVCAEGFAPIPHE 400
+ D CV E PC+R + QC ++ T LC C+ G A PH
Sbjct: 329 GFGPDPTFSSCVPDPPVISEEKGPCYRLVSSGRQCMHPLSVHLTKQLCCCSVGKAWGPH- 387
Query: 401 PHRCQMFCNQTACPADCDPNTQASCE-CPEG 430
C+ CP P T A E CP G
Sbjct: 388 ---CE------KCPL---PGTAAFKEICPGG 406
Score = 42.0 bits (97), Expect = 0.002
Identities = 20/54 (37%), Positives = 28/54 (51%), Gaps = 4/54 (7%)
Query: 306 YSCMCETGYRLAADQHRCEDVDDCIL---EPSPCPQ-RCVNTQGGFECHCYPNY 355
Y+C C GY L + C DV++C S C +C+NT G ++C C P Y
Sbjct: 1318 YTCDCFDGYHLDTAKMTCVDVNECDELNNRMSLCKNAKCINTDGSYKCLCLPGY 1371
Score = 39.7 bits (91), Expect = 0.008
Identities = 20/49 (40%), Positives = 26/49 (53%), Gaps = 5/49 (10%)
Query: 426 ECPEGYILDDGFICTDIDECENGGFC-SGVCHNLPGTFECIC----GPD 469
EC GY + C DI+EC+ G C +G C N G++ C C GPD
Sbjct: 285 ECLPGYKRVNNTFCQDINECQLQGVCPNGECLNTMGSYRCTCKIGFGPD 333
Score = 36.6 bits (83), Expect = 0.064
Identities = 17/51 (33%), Positives = 27/51 (52%), Gaps = 6/51 (11%)
Query: 424 SCECPEGYILDDG-FICTDIDECEN----GGFCSGV-CHNLPGTFECICGP 468
+C+C +GY LD C D++EC+ C C N G+++C+C P
Sbjct: 1319 TCDCFDGYHLDTAKMTCVDVNECDELNNRMSLCKNAKCINTDGSYKCLCLP 1369
Score = 35.8 bits (81), Expect = 0.11
Identities = 23/73 (31%), Positives = 32/73 (43%), Gaps = 9/73 (12%)
Query: 339 RCVNTQGGFECHCYPNY--DLVDGECVEPVDPCFRAN-----CEYQCQPLNQTSYLCVCA 391
RCV Q G+ C C+ Y D CV+ V+ C N C+ SY C+C
Sbjct: 1310 RCVRVQEGYTCDCFDGYHLDTAKMTCVD-VNECDELNNRMSLCKNAKCINTDGSYKCLCL 1368
Query: 392 EGFAPIPHEPHRC 404
G+ P +P+ C
Sbjct: 1369 PGYVP-SDKPNYC 1380
Score = 31.2 bits (69), Expect = 2.7
Identities = 24/80 (30%), Positives = 34/80 (42%), Gaps = 12/80 (15%)
Query: 242 AWDCSVENGGCEHA-CNAIPGAPRCQCPAGAALQADGRSCTASATQSCNDL------CEH 294
A +C + NG CE+ C + C C G L +C C++L C++
Sbjct: 1297 AEECGILNG-CENGRCVRVQEGYTCDCFDGYHLDTAKMTCVD--VNECDELNNRMSLCKN 1353
Query: 295 FCVPNPDQPGSYSCMCETGY 314
N D GSY C+C GY
Sbjct: 1354 AKCINTD--GSYKCLCLPGY 1371
>gi|194328809 latent transforming growth factor beta binding protein 3
isoform 1 [Homo sapiens]
Length = 1303
Score = 110 bits (276), Expect = 3e-24
Identities = 78/266 (29%), Positives = 106/266 (39%), Gaps = 58/266 (21%)
Query: 256 CNAIPGAPRCQCPAGAALQADGRSCTASATQSCNDLCEHFCVPNPDQPGSYSCMCETGYR 315
C +PG+ RC C G A DGRSC D+C++ N PGS+ C C +GY
Sbjct: 759 CENLPGSFRCTCAQGYAPAPDGRSCLDVDECEAGDVCDNGICSNT--PGSFQCQCLSGYH 816
Query: 316 LAADQHRCEDVDDCILEPSPCPQRCVNTQGGFECHCYPNYDLVDGECVEPVDPCFR--AN 373
L+ D+ CED+D+C + C+NT G + C C + LV G + +D C + +
Sbjct: 817 LSRDRSHCEDIDECDFPAACIGGDCINTNGSYRCLCPQGHRLVGGRKCQDIDECSQDPSL 876
Query: 374 C--EYQCQPLNQTSYLCVCAEGFAPI-----------PHEPHRCQM------FCNQT--- 411
C C+ L Q SY+CVC EGF P PH C + FC+
Sbjct: 877 CLPHGACKNL-QGSYVCVCDEGFTPTQDQHGCEEVEQPHHKKECYLNFDDTVFCDSVLAT 935
Query: 412 ----------------------ACPADCDPNTQASCECPEGYILDDGFI------CTDID 443
CP + C +GY D+ + DID
Sbjct: 936 NVTQQECCCSLGAGWGDHCEIYPCPVYSSAEFHSLCPDGKGYTQDNNIVNYGIPAHRDID 995
Query: 444 ECENGG--FC-SGVCHNLPGTFECIC 466
EC G C G C N +EC C
Sbjct: 996 ECMLFGSEICKEGKCVNTQPGYECYC 1021
Score = 100 bits (250), Expect = 3e-21
Identities = 89/301 (29%), Positives = 117/301 (38%), Gaps = 63/301 (20%)
Query: 224 CTAPPGAVQGHWAREAPGAWDCSVENGGCEHA-CNAIPGAPRCQCPAGAALQ--ADGRSC 280
C PG R +C E G C G+ C C G L A GRSC
Sbjct: 599 CHCNPGYRSHPQHRYCVDVNECEAEPCGPGRGICMNTGGSYNCHCNRGYRLHVGAGGRSC 658
Query: 281 TASATQSCNDLCEH--FCVPNPDQPGSYSCMCETGYRLAADQHR-CEDVDDCILEPSPCP 337
+ LC FC+ + PG Y C C GYRL A + CED+D+C +PS CP
Sbjct: 659 VDLNECAKPHLCGDGGFCI---NFPGHYKCNCYPGYRLKASRPPVCEDIDEC-RDPSSCP 714
Query: 338 Q-RCVNTQGGFEC-HCYPNYDLVDGECVEPVDPCFRAN--CEYQCQPLNQTSYLCVCAEG 393
+C N G F+C C P Y G V+ C + C+ L S+ C CA+G
Sbjct: 715 DGKCENKPGSFKCIACQPGYRSQGGGACRDVNECAEGSPCSPGWCENL-PGSFRCTCAQG 773
Query: 394 FAPIPH-----EPHRCQM--FCNQTAC--------------------------------P 414
+AP P + C+ C+ C P
Sbjct: 774 YAPAPDGRSCLDVDECEAGDVCDNGICSNTPGSFQCQCLSGYHLSRDRSHCEDIDECDFP 833
Query: 415 ADC------DPNTQASCECPEGYILDDGFICTDIDEC-ENGGFC--SGVCHNLPGTFECI 465
A C + N C CP+G+ L G C DIDEC ++ C G C NL G++ C+
Sbjct: 834 AACIGGDCINTNGSYRCLCPQGHRLVGGRKCQDIDECSQDPSLCLPHGACKNLQGSYVCV 893
Query: 466 C 466
C
Sbjct: 894 C 894
Score = 94.7 bits (234), Expect = 2e-19
Identities = 71/215 (33%), Positives = 96/215 (44%), Gaps = 19/215 (8%)
Query: 290 DLCEHF-CVPNPDQPGSYSCMCETGYRLAADQHRCEDVDDCILEP-SPCPQRCVNTQGGF 347
++C H CVP P YSC C GYR C DV++C EP P C+NT G +
Sbjct: 583 NICGHGECVPGPPD---YSCHCNPGYRSHPQHRYCVDVNECEAEPCGPGRGICMNTGGSY 639
Query: 348 ECHCYPNYDLVDG----ECVEPVDPCFRAN-CEYQCQPLN-QTSYLCVCAEGFAPIPHEP 401
CHC Y L G CV+ ++ C + + C +N Y C C G+ P
Sbjct: 640 NCHCNRGYRLHVGAGGRSCVD-LNECAKPHLCGDGGFCINFPGHYKCNCYPGYRLKASRP 698
Query: 402 HRCQMF--C-NQTACP-ADCD--PNTQASCECPEGYILDDGFICTDIDECENGGFCS-GV 454
C+ C + ++CP C+ P + C GY G C D++EC G CS G
Sbjct: 699 PVCEDIDECRDPSSCPDGKCENKPGSFKCIACQPGYRSQGGGACRDVNECAEGSPCSPGW 758
Query: 455 CHNLPGTFECICGPDSALARHIGTDCDSGKVDGGD 489
C NLPG+F C C A A + D + + GD
Sbjct: 759 CENLPGSFRCTCAQGYAPAPDGRSCLDVDECEAGD 793
Score = 89.7 bits (221), Expect = 6e-18
Identities = 77/315 (24%), Positives = 116/315 (36%), Gaps = 89/315 (28%)
Query: 235 WAREAPGAWDCSVENG--------------GCEHA-------CNAIPGAPRCQCPAGAAL 273
W PG++ C+ G CE C+ PG+ +CQC +G L
Sbjct: 758 WCENLPGSFRCTCAQGYAPAPDGRSCLDVDECEAGDVCDNGICSNTPGSFQCQCLSGYHL 817
Query: 274 QADGRSCTASATQSCNDLCEH--FCVPNP--DQPGSYSCMCETGYRLAADQHRCEDVDDC 329
D C D C+ C+ + GSY C+C G+RL + +C+D+D+C
Sbjct: 818 SRDRSHCEDI------DECDFPAACIGGDCINTNGSYRCLCPQGHRLVGGR-KCQDIDEC 870
Query: 330 ILEPSPCPQR--CVNTQGGFEC-------------------------HCYPNYD------ 356
+PS C C N QG + C CY N+D
Sbjct: 871 SQDPSLCLPHGACKNLQGSYVCVCDEGFTPTQDQHGCEEVEQPHHKKECYLNFDDTVFCD 930
Query: 357 ------LVDGECVEPVDPCFRANCE-YQCQPLNQTSYLCVCAEGFA------------PI 397
+ EC + + +CE Y C + + +C +G P
Sbjct: 931 SVLATNVTQQECCCSLGAGWGDHCEIYPCPVYSSAEFHSLCPDGKGYTQDNNIVNYGIPA 990
Query: 398 PHEPHRCQMFCNQTACPADCDPNTQA--SCECPEGYILDDGFI-CTDIDECENGGFC-SG 453
+ C +F ++ C NTQ C C +G+ D + C D+DEC + C +G
Sbjct: 991 HRDIDECMLFGSEICKEGKC-VNTQPGYECYCKQGFYYDGNLLECVDVDECLDESNCRNG 1049
Query: 454 VCHNLPGTFECICGP 468
VC N G + C C P
Sbjct: 1050 VCENTRGGYRCACTP 1064
Score = 67.4 bits (163), Expect = 3e-11
Identities = 63/218 (28%), Positives = 85/218 (38%), Gaps = 52/218 (23%)
Query: 267 CPAGAALQADGRSCTASATQSCNDLCEHFCVPNPDQPGSYSCMCETGYRLAADQ------ 320
C + A + C S D CE + P +S +C G D
Sbjct: 929 CDSVLATNVTQQECCCSLGAGWGDHCEIYPCPVYSSAEFHS-LCPDGKGYTQDNNIVNYG 987
Query: 321 ---HRCEDVDDCILEPSP-CPQ-RCVNTQGGFECHCYPNYDLVDG---ECVEPVDPCF-R 371
HR D+D+C+L S C + +CVNTQ G+EC+C + DG ECV+ VD C
Sbjct: 988 IPAHR--DIDECMLFGSEICKEGKCVNTQPGYECYCKQGF-YYDGNLLECVD-VDECLDE 1043
Query: 372 ANCEYQCQPLNQTSYLCVCAEGFAPIPHEPHRCQMFCNQTACPADCDPNTQASCECPEGY 431
+NC + Y C C PA+ P Q C PE
Sbjct: 1044 SNCRNGVCENTRGGYRCACTP---------------------PAEYSP-AQRQCLSPEEM 1081
Query: 432 ILDDGFICTDIDECENGGFCS-GVCHNLPGTFECICGP 468
D+DEC++ C G C NLPG++ C C P
Sbjct: 1082 ---------DVDECQDPAACRPGRCVNLPGSYRCECRP 1110
Score = 57.4 bits (137), Expect = 4e-08
Identities = 78/297 (26%), Positives = 104/297 (35%), Gaps = 89/297 (29%)
Query: 257 NAIPGAPRCQCPAGAALQADGRSCTASATQSC-------NDLCEHFCVPNPDQPGSYSCM 309
N PG C C G DG C N +CE+ G Y C
Sbjct: 1012 NTQPGY-ECYCKQG--FYYDGNLLECVDVDECLDESNCRNGVCEN-------TRGGYRCA 1061
Query: 310 CETGYRLAADQHRC-----EDVDDCILEPSPC-PQRCVNTQGGFECHCYPNY-------- 355
C + Q +C DVD+C +P+ C P RCVN G + C C P +
Sbjct: 1062 CTPPAEYSPAQRQCLSPEEMDVDEC-QDPAACRPGRCVNLPGSYRCECRPPWVPGPSGRD 1120
Query: 356 ---------------DLV------DGECVEPV--------DPCFR------ANCEYQCQP 380
D+ DG C P+ D C R A C C P
Sbjct: 1121 CQLPESPAERAPERRDVCWSQRGEDGMCAGPLAGPALTFDDCCCRQGRGWGAQCR-PCPP 1179
Query: 381 LNQTSYLCVCAEG-------FAPI-----PHEPHRCQMFCNQTACPAD-CDPNTQ-ASCE 426
S+ C ++ +P+ P + + ++ C + C P A CE
Sbjct: 1180 RGAGSH-CPTSQSESNSFWDTSPLLLGKPPRDEDSSEEDSDECRCVSGRCVPRPGGAVCE 1238
Query: 427 CPEGYILDDGFI-CTDIDEC----ENGGFC-SGVCHNLPGTFECICGPDSALARHIG 477
CP G+ LD C DIDEC + G C S C N G+F C+C A +R G
Sbjct: 1239 CPGGFQLDASRARCVDIDECRELNQRGLLCKSERCVNTSGSFRCVCKAGFARSRPHG 1295
Score = 54.7 bits (130), Expect = 2e-07
Identities = 50/169 (29%), Positives = 66/169 (39%), Gaps = 20/169 (11%)
Query: 270 GAALQADGRSCTASATQSCNDLCEHFCVPNPDQPGSYSCMCETGYRLAADQHRCEDVDDC 329
G D C ++ C E CV QPG Y C C+ G+ + C DVD+C
Sbjct: 987 GIPAHRDIDECMLFGSEICK---EGKCVNT--QPG-YECYCKQGFYYDGNLLECVDVDEC 1040
Query: 330 ILEPSPCPQRCVNTQGGFECHCYP--NYDLVDGECVEP----VDPC-FRANCE-YQCQPL 381
+ E + C NT+GG+ C C P Y +C+ P VD C A C +C L
Sbjct: 1041 LDESNCRNGVCENTRGGYRCACTPPAEYSPAQRQCLSPEEMDVDECQDPAACRPGRCVNL 1100
Query: 382 NQTSYLCVCAEGFAPIPHEPHRCQMFCNQTACPADCDPNTQASCECPEG 430
SY C C + P P C PA+ P + C G
Sbjct: 1101 -PGSYRCECRPPWVPGPSGRD-----CQLPESPAERAPERRDVCWSQRG 1143
Score = 50.8 bits (120), Expect = 3e-06
Identities = 43/139 (30%), Positives = 59/139 (42%), Gaps = 23/139 (16%)
Query: 304 GSYSCMCETGYRLAADQHRCEDVDDCILEPSPCPQR-CVNTQGGFECHCYPNYDLVDG-- 360
G C GY+ H C+D+++C + P C C+N G + C C P + L
Sbjct: 335 GEVGADCPQGYKRLNSTH-CQDINECAM-PGVCRHGDCLNNPGSYRCVCPPGHSLGPSRT 392
Query: 361 ECV----EPVDPCFR-ANCEYQCQ-PLNQ--TSYLCVCAEGFAPIPHEPHRCQMFCNQTA 412
+C+ E CFR + E+QCQ PL T LC C+ G A RCQ
Sbjct: 393 QCIADKPEEKSLCFRLVSPEHQCQHPLTTRLTRQLCCCSVGKA----WGARCQ------R 442
Query: 413 CPADCDPNTQASCECPEGY 431
CP D + C +GY
Sbjct: 443 CPTDGTAAFKEICPAGKGY 461
Score = 46.6 bits (109), Expect = 6e-05
Identities = 20/52 (38%), Positives = 29/52 (55%), Gaps = 1/52 (1%)
Query: 422 QASCECPEGYILDDGFICTDIDECENGGFC-SGVCHNLPGTFECICGPDSAL 472
+ +CP+GY + C DI+EC G C G C N PG++ C+C P +L
Sbjct: 336 EVGADCPQGYKRLNSTHCQDINECAMPGVCRHGDCLNNPGSYRCVCPPGHSL 387
Score = 36.6 bits (83), Expect = 0.064
Identities = 34/124 (27%), Positives = 44/124 (35%), Gaps = 22/124 (17%)
Query: 220 LQLMCTAPPGAVQGHWAREAPGAW------------DCSVENGGCEHA-CNAIPGAPRCQ 266
LQ PG V+G + P + +C++ G C H C PG+ RC
Sbjct: 322 LQYTGVQKPGPVRGEVGADCPQGYKRLNSTHCQDINECAMP-GVCRHGDCLNNPGSYRCV 380
Query: 267 CPAGAALQADGRSCTASATQSCNDLC------EHFCV-PNPDQPGSYSCMCETGYRLAAD 319
CP G +L C A + LC EH C P + C C G A
Sbjct: 381 CPPGHSLGPSRTQCIADKPEE-KSLCFRLVSPEHQCQHPLTTRLTRQLCCCSVGKAWGAR 439
Query: 320 QHRC 323
RC
Sbjct: 440 CQRC 443
Score = 33.5 bits (75), Expect = 0.54
Identities = 18/72 (25%), Positives = 29/72 (40%), Gaps = 6/72 (8%)
Query: 256 CNAIPGAPRCQCPAGAALQADGRSCTASATQSCNDLCEHFCVPNPDQ----PGSYSCMCE 311
C PG C+CP G L A C C +L + + ++ GS+ C+C+
Sbjct: 1228 CVPRPGGAVCECPGGFQLDASRARCV--DIDECRELNQRGLLCKSERCVNTSGSFRCVCK 1285
Query: 312 TGYRLAADQHRC 323
G+ + C
Sbjct: 1286 AGFARSRPHGAC 1297
>gi|18497288 latent transforming growth factor beta binding protein 3
isoform 2 [Homo sapiens]
Length = 1256
Score = 110 bits (276), Expect = 3e-24
Identities = 78/266 (29%), Positives = 106/266 (39%), Gaps = 58/266 (21%)
Query: 256 CNAIPGAPRCQCPAGAALQADGRSCTASATQSCNDLCEHFCVPNPDQPGSYSCMCETGYR 315
C +PG+ RC C G A DGRSC D+C++ N PGS+ C C +GY
Sbjct: 759 CENLPGSFRCTCAQGYAPAPDGRSCLDVDECEAGDVCDNGICSNT--PGSFQCQCLSGYH 816
Query: 316 LAADQHRCEDVDDCILEPSPCPQRCVNTQGGFECHCYPNYDLVDGECVEPVDPCFR--AN 373
L+ D+ CED+D+C + C+NT G + C C + LV G + +D C + +
Sbjct: 817 LSRDRSHCEDIDECDFPAACIGGDCINTNGSYRCLCPQGHRLVGGRKCQDIDECSQDPSL 876
Query: 374 C--EYQCQPLNQTSYLCVCAEGFAPI-----------PHEPHRCQM------FCNQT--- 411
C C+ L Q SY+CVC EGF P PH C + FC+
Sbjct: 877 CLPHGACKNL-QGSYVCVCDEGFTPTQDQHGCEEVEQPHHKKECYLNFDDTVFCDSVLAT 935
Query: 412 ----------------------ACPADCDPNTQASCECPEGYILDDGFI------CTDID 443
CP + C +GY D+ + DID
Sbjct: 936 NVTQQECCCSLGAGWGDHCEIYPCPVYSSAEFHSLCPDGKGYTQDNNIVNYGIPAHRDID 995
Query: 444 ECENGG--FC-SGVCHNLPGTFECIC 466
EC G C G C N +EC C
Sbjct: 996 ECMLFGSEICKEGKCVNTQPGYECYC 1021
Score = 100 bits (250), Expect = 3e-21
Identities = 89/301 (29%), Positives = 117/301 (38%), Gaps = 63/301 (20%)
Query: 224 CTAPPGAVQGHWAREAPGAWDCSVENGGCEHA-CNAIPGAPRCQCPAGAALQ--ADGRSC 280
C PG R +C E G C G+ C C G L A GRSC
Sbjct: 599 CHCNPGYRSHPQHRYCVDVNECEAEPCGPGRGICMNTGGSYNCHCNRGYRLHVGAGGRSC 658
Query: 281 TASATQSCNDLCEH--FCVPNPDQPGSYSCMCETGYRLAADQHR-CEDVDDCILEPSPCP 337
+ LC FC+ + PG Y C C GYRL A + CED+D+C +PS CP
Sbjct: 659 VDLNECAKPHLCGDGGFCI---NFPGHYKCNCYPGYRLKASRPPVCEDIDEC-RDPSSCP 714
Query: 338 Q-RCVNTQGGFEC-HCYPNYDLVDGECVEPVDPCFRAN--CEYQCQPLNQTSYLCVCAEG 393
+C N G F+C C P Y G V+ C + C+ L S+ C CA+G
Sbjct: 715 DGKCENKPGSFKCIACQPGYRSQGGGACRDVNECAEGSPCSPGWCENL-PGSFRCTCAQG 773
Query: 394 FAPIPH-----EPHRCQM--FCNQTAC--------------------------------P 414
+AP P + C+ C+ C P
Sbjct: 774 YAPAPDGRSCLDVDECEAGDVCDNGICSNTPGSFQCQCLSGYHLSRDRSHCEDIDECDFP 833
Query: 415 ADC------DPNTQASCECPEGYILDDGFICTDIDEC-ENGGFC--SGVCHNLPGTFECI 465
A C + N C CP+G+ L G C DIDEC ++ C G C NL G++ C+
Sbjct: 834 AACIGGDCINTNGSYRCLCPQGHRLVGGRKCQDIDECSQDPSLCLPHGACKNLQGSYVCV 893
Query: 466 C 466
C
Sbjct: 894 C 894
Score = 94.7 bits (234), Expect = 2e-19
Identities = 71/215 (33%), Positives = 96/215 (44%), Gaps = 19/215 (8%)
Query: 290 DLCEHF-CVPNPDQPGSYSCMCETGYRLAADQHRCEDVDDCILEP-SPCPQRCVNTQGGF 347
++C H CVP P YSC C GYR C DV++C EP P C+NT G +
Sbjct: 583 NICGHGECVPGPPD---YSCHCNPGYRSHPQHRYCVDVNECEAEPCGPGRGICMNTGGSY 639
Query: 348 ECHCYPNYDLVDG----ECVEPVDPCFRAN-CEYQCQPLN-QTSYLCVCAEGFAPIPHEP 401
CHC Y L G CV+ ++ C + + C +N Y C C G+ P
Sbjct: 640 NCHCNRGYRLHVGAGGRSCVD-LNECAKPHLCGDGGFCINFPGHYKCNCYPGYRLKASRP 698
Query: 402 HRCQMF--C-NQTACP-ADCD--PNTQASCECPEGYILDDGFICTDIDECENGGFCS-GV 454
C+ C + ++CP C+ P + C GY G C D++EC G CS G
Sbjct: 699 PVCEDIDECRDPSSCPDGKCENKPGSFKCIACQPGYRSQGGGACRDVNECAEGSPCSPGW 758
Query: 455 CHNLPGTFECICGPDSALARHIGTDCDSGKVDGGD 489
C NLPG+F C C A A + D + + GD
Sbjct: 759 CENLPGSFRCTCAQGYAPAPDGRSCLDVDECEAGD 793
Score = 89.7 bits (221), Expect = 6e-18
Identities = 77/315 (24%), Positives = 116/315 (36%), Gaps = 89/315 (28%)
Query: 235 WAREAPGAWDCSVENG--------------GCEHA-------CNAIPGAPRCQCPAGAAL 273
W PG++ C+ G CE C+ PG+ +CQC +G L
Sbjct: 758 WCENLPGSFRCTCAQGYAPAPDGRSCLDVDECEAGDVCDNGICSNTPGSFQCQCLSGYHL 817
Query: 274 QADGRSCTASATQSCNDLCEH--FCVPNP--DQPGSYSCMCETGYRLAADQHRCEDVDDC 329
D C D C+ C+ + GSY C+C G+RL + +C+D+D+C
Sbjct: 818 SRDRSHCEDI------DECDFPAACIGGDCINTNGSYRCLCPQGHRLVGGR-KCQDIDEC 870
Query: 330 ILEPSPCPQR--CVNTQGGFEC-------------------------HCYPNYD------ 356
+PS C C N QG + C CY N+D
Sbjct: 871 SQDPSLCLPHGACKNLQGSYVCVCDEGFTPTQDQHGCEEVEQPHHKKECYLNFDDTVFCD 930
Query: 357 ------LVDGECVEPVDPCFRANCE-YQCQPLNQTSYLCVCAEGFA------------PI 397
+ EC + + +CE Y C + + +C +G P
Sbjct: 931 SVLATNVTQQECCCSLGAGWGDHCEIYPCPVYSSAEFHSLCPDGKGYTQDNNIVNYGIPA 990
Query: 398 PHEPHRCQMFCNQTACPADCDPNTQA--SCECPEGYILDDGFI-CTDIDECENGGFC-SG 453
+ C +F ++ C NTQ C C +G+ D + C D+DEC + C +G
Sbjct: 991 HRDIDECMLFGSEICKEGKC-VNTQPGYECYCKQGFYYDGNLLECVDVDECLDESNCRNG 1049
Query: 454 VCHNLPGTFECICGP 468
VC N G + C C P
Sbjct: 1050 VCENTRGGYRCACTP 1064
Score = 62.8 bits (151), Expect = 8e-10
Identities = 73/270 (27%), Positives = 96/270 (35%), Gaps = 70/270 (25%)
Query: 270 GAALQADGRSCTASATQSCNDLCEHFCVPNPDQPGSYSCMCETGYRLAADQHRCEDVDDC 329
G D C ++ C E CV QPG Y C C+ G+ + C DVD+C
Sbjct: 987 GIPAHRDIDECMLFGSEICK---EGKCVNT--QPG-YECYCKQGFYYDGNLLECVDVDEC 1040
Query: 330 ILEPSPCPQRCVNTQGGFECHCYP--NYDLVDGECVEPVD----PCFRANCEYQ------ 377
+ E + C NT+GG+ C C P Y +C+ P + P R C Q
Sbjct: 1041 LDESNCRNGVCENTRGGYRCACTPPAEYSPAQRQCLSPEEMERAPERRDVCWSQRGEDGM 1100
Query: 378 -CQPLNQTSYL---CVCAEG------FAPIPHEPHRCQMFCNQTAC-------------- 413
PL + C C +G P P P C +
Sbjct: 1101 CAGPLAGPALTFDDCCCRQGRGWGAQCRPCP--PRGAGSHCPTSQSESNSFWDTSPLLLG 1158
Query: 414 --PADCDPNTQAS------------------CECPEGYILDDGFI-CTDIDEC----ENG 448
P D D + + S CECP G+ LD C DIDEC + G
Sbjct: 1159 KPPRDEDSSEEDSDECRCVSGRCVPRPGGAVCECPGGFQLDASRARCVDIDECRELNQRG 1218
Query: 449 GFC-SGVCHNLPGTFECICGPDSALARHIG 477
C S C N G+F C+C A +R G
Sbjct: 1219 LLCKSERCVNTSGSFRCVCKAGFARSRPHG 1248
Score = 50.8 bits (120), Expect = 3e-06
Identities = 43/139 (30%), Positives = 59/139 (42%), Gaps = 23/139 (16%)
Query: 304 GSYSCMCETGYRLAADQHRCEDVDDCILEPSPCPQR-CVNTQGGFECHCYPNYDLVDG-- 360
G C GY+ H C+D+++C + P C C+N G + C C P + L
Sbjct: 335 GEVGADCPQGYKRLNSTH-CQDINECAM-PGVCRHGDCLNNPGSYRCVCPPGHSLGPSRT 392
Query: 361 ECV----EPVDPCFR-ANCEYQCQ-PLNQ--TSYLCVCAEGFAPIPHEPHRCQMFCNQTA 412
+C+ E CFR + E+QCQ PL T LC C+ G A RCQ
Sbjct: 393 QCIADKPEEKSLCFRLVSPEHQCQHPLTTRLTRQLCCCSVGKA----WGARCQ------R 442
Query: 413 CPADCDPNTQASCECPEGY 431
CP D + C +GY
Sbjct: 443 CPTDGTAAFKEICPAGKGY 461
Score = 46.6 bits (109), Expect = 6e-05
Identities = 20/52 (38%), Positives = 29/52 (55%), Gaps = 1/52 (1%)
Query: 422 QASCECPEGYILDDGFICTDIDECENGGFC-SGVCHNLPGTFECICGPDSAL 472
+ +CP+GY + C DI+EC G C G C N PG++ C+C P +L
Sbjct: 336 EVGADCPQGYKRLNSTHCQDINECAMPGVCRHGDCLNNPGSYRCVCPPGHSL 387
Score = 36.6 bits (83), Expect = 0.064
Identities = 34/124 (27%), Positives = 44/124 (35%), Gaps = 22/124 (17%)
Query: 220 LQLMCTAPPGAVQGHWAREAPGAW------------DCSVENGGCEHA-CNAIPGAPRCQ 266
LQ PG V+G + P + +C++ G C H C PG+ RC
Sbjct: 322 LQYTGVQKPGPVRGEVGADCPQGYKRLNSTHCQDINECAMP-GVCRHGDCLNNPGSYRCV 380
Query: 267 CPAGAALQADGRSCTASATQSCNDLC------EHFCV-PNPDQPGSYSCMCETGYRLAAD 319
CP G +L C A + LC EH C P + C C G A
Sbjct: 381 CPPGHSLGPSRTQCIADKPEE-KSLCFRLVSPEHQCQHPLTTRLTRQLCCCSVGKAWGAR 439
Query: 320 QHRC 323
RC
Sbjct: 440 CQRC 443
Score = 33.5 bits (75), Expect = 0.54
Identities = 18/72 (25%), Positives = 29/72 (40%), Gaps = 6/72 (8%)
Query: 256 CNAIPGAPRCQCPAGAALQADGRSCTASATQSCNDLCEHFCVPNPDQ----PGSYSCMCE 311
C PG C+CP G L A C C +L + + ++ GS+ C+C+
Sbjct: 1181 CVPRPGGAVCECPGGFQLDASRARCV--DIDECRELNQRGLLCKSERCVNTSGSFRCVCK 1238
Query: 312 TGYRLAADQHRC 323
G+ + C
Sbjct: 1239 AGFARSRPHGAC 1250
>gi|110347437 latent transforming growth factor beta binding protein
4 isoform c [Homo sapiens]
Length = 1557
Score = 106 bits (264), Expect = 7e-23
Identities = 90/317 (28%), Positives = 117/317 (36%), Gaps = 76/317 (23%)
Query: 210 GSSAAVAPLGLQLMCTAPPGAVQGHWAREAPGAWDCSVENGGCEH-ACNAIPGAPRCQCP 268
GS V P G Q AP GA +C+ G C AC +PG+ RC CP
Sbjct: 583 GSFLCVCPAGYQ---AAPHGA-------SCQDVDECTQSPGLCGRGACKNLPGSFRCVCP 632
Query: 269 AG---AALQADGRSCTASATQSCNDLCEHFCVPNPDQPGSYSCMCETGYRLAADQHRCED 325
AG +A + D C C++ GS+ C C G+R C+D
Sbjct: 633 AGFRGSACEEDVDECAQEPPPCGPGRCDNTA-------GSFHCACPAGFRSRGPGAPCQD 685
Query: 326 VDDCILEPSPCPQ-RCVNTQGGFECHCYPNY--DLVDGECVE----------PVDPCFRA 372
VD+C P PC RC NT+G F+C C + + EC + P C +
Sbjct: 686 VDECARSPPPCTYGRCENTEGSFQCVCPMGFQPNTAGSECEDVDECENHLACPGQECVNS 745
Query: 373 NCEYQCQPL--------------------------------NQTSYLCVCAEGFAPIPHE 400
+QC+ + S+ C CA G+
Sbjct: 746 PGSFQCRTCPSGHHLHRGRCTDVDECSSGAPPCGPHGHCTNTEGSFRCSCAPGYRAPSGR 805
Query: 401 PHRCQMFCNQTACPADCDP-----NTQAS--CECPEGYILDD-GFICTDIDECENGGFC- 451
P C N+ C P NT S C C GY G C D+DEC C
Sbjct: 806 PGPCADV-NECLEGDFCFPHGECLNTDGSFACTCAPGYRPGPRGASCLDVDECSEEDLCQ 864
Query: 452 SGVCHNLPGTFECICGP 468
SG+C N G+FECIC P
Sbjct: 865 SGICTNTDGSFECICPP 881
Score = 99.0 bits (245), Expect = 1e-20
Identities = 93/302 (30%), Positives = 112/302 (37%), Gaps = 73/302 (24%)
Query: 256 CNAIPGAPRCQCPAGAALQADGRSCTASATQSCNDLCEHFCVPNP-------DQPGSYSC 308
C + P C C +G L G C D+ E VP P + PGS+ C
Sbjct: 494 CISRPSGYTCACDSGFRLSPQGTRCI--------DVDECRRVPPPCAPGRCENSPGSFRC 545
Query: 309 MCETGYRLAADQHRCEDVDDCILEPSPCP-QRCVNTQGGFECHCYPNYDLV-DGECVEPV 366
+C G+R C DVD+C P PC RC NT G F C C Y G + V
Sbjct: 546 VCGPGFRAGPRAAECLDVDECHRVPPPCDLGRCENTPGSFLCVCPAGYQAAPHGASCQDV 605
Query: 367 DPCFRAN--CEYQCQPLNQTSYLCVCAEGF--------------APIPHEPHRCQMFCN- 409
D C ++ C S+ CVC GF P P P RC
Sbjct: 606 DECTQSPGLCGRGACKNLPGSFRCVCPAGFRGSACEEDVDECAQEPPPCGPGRCDNTAGS 665
Query: 410 -QTACPA------------DCD--------------PNTQAS--CECPEGYILDD-GFIC 439
ACPA D D NT+ S C CP G+ + G C
Sbjct: 666 FHCACPAGFRSRGPGAPCQDVDECARSPPPCTYGRCENTEGSFQCVCPMGFQPNTAGSEC 725
Query: 440 TDIDECENGGFCSG-VCHNLPGTFEC-ICGPDSALARHIGTDCDSGKVDGGDSGSGEPPP 497
D+DECEN C G C N PG+F+C C L R TD D + SG PP
Sbjct: 726 EDVDECENHLACPGQECVNSPGSFQCRTCPSGHHLHRGRCTDVD-------ECSSGAPPC 778
Query: 498 SP 499
P
Sbjct: 779 GP 780
Score = 99.0 bits (245), Expect = 1e-20
Identities = 79/233 (33%), Positives = 98/233 (42%), Gaps = 29/233 (12%)
Query: 256 CNAIPGAPRCQCPAGAALQADGRSCTASATQSCNDLCEHFCVPNPD---QPGSYSCMCET 312
C G+ RC C G + GR + C L FC P+ + GS++C C
Sbjct: 784 CTNTEGSFRCSCAPGYRAPS-GRPGPCADVNEC--LEGDFCFPHGECLNTDGSFACTCAP 840
Query: 313 GYRLAADQHRCEDVDDCILEPSPCPQRCVNTQGGFECHCYPNY----DLVDGECVEPVDP 368
GYR C DVD+C E C NT G FEC C P + DL C++ VD
Sbjct: 841 GYRPGPRGASCLDVDECSEEDLCQSGICTNTDGSFECICPPGHRAGPDL--ASCLD-VDE 897
Query: 369 CFR---ANCEYQCQPLNQTSYLCV--CAEGFAPIPH----EPHRCQMFCNQTACPADCDP 419
C A C Q + SY CV C G+ P + CQ + C A
Sbjct: 898 CRERGPALCGSQRCENSPGSYRCVRDCDPGYHAGPEGTCDDVDECQEY-GPEICGAQRCE 956
Query: 420 NTQASCE----CPEGYILDDGFICTDIDECENGGFCS--GVCHNLPGTFECIC 466
NT S C GY G C D+DEC N FC VC NLPG+F+C+C
Sbjct: 957 NTPGSYRCTPACDPGYQPTPGGGCQDVDECRNRSFCGAHAVCQNLPGSFQCLC 1009
Score = 87.8 bits (216), Expect = 2e-17
Identities = 84/307 (27%), Positives = 110/307 (35%), Gaps = 61/307 (19%)
Query: 224 CTAPPGAVQGHWAREAPGAWDCSVENGGCEHACNAIPGAPRCQCPAGAALQADGRSCTAS 283
CT PG G +CS E+ C G+ C CP G D SC
Sbjct: 836 CTCAPGYRPGPRGASCLDVDECSEEDLCQSGICTNTDGSFECICPPGHRAGPDLASCL-- 893
Query: 284 ATQSCNDLCEHFCVPN--PDQPGSYSCM--CETGYRLAADQHRCEDVDDC-ILEPSPC-P 337
C + C + PGSY C+ C+ GY A + C+DVD+C P C
Sbjct: 894 DVDECRERGPALCGSQRCENSPGSYRCVRDCDPGYH-AGPEGTCDDVDECQEYGPEICGA 952
Query: 338 QRCVNTQGGFEC--HCYPNYDLVDGECVEPVDPCFRANCEYQCQPLNQTSYLCVCAEGFA 395
QRC NT G + C C P Y G + VD C
Sbjct: 953 QRCENTPGSYRCTPACDPGYQPTPGGGCQDVDEC-------------------------- 986
Query: 396 PIPHEPHRCQMFCNQTACPADCDPNTQASCECPEGYI-LDDGFICTDIDECEN-GGFC-S 452
R + FC A + + Q C C +GY DG C D++ECE G C +
Sbjct: 987 -------RNRSFCGAHAVCQNLPGSFQ--CLCDQGYEGARDGRHCVDVNECETLQGVCGA 1037
Query: 453 GVCHNLPGTFECICGP-----DSALARHIGTDCDSGKVDGGDSGS-------GEPPPSPT 500
+C N+ G+F C+C D R + +G G + PPP P
Sbjct: 1038 ALCENVEGSFLCVCPNSPEEFDPMTGRCVPPRTSAGTFPGSQPQAPASPVLPARPPPPPL 1097
Query: 501 PGSTLTP 507
P TP
Sbjct: 1098 PRRPSTP 1104
Score = 77.4 bits (189), Expect = 3e-14
Identities = 62/191 (32%), Positives = 79/191 (41%), Gaps = 41/191 (21%)
Query: 329 CILEPSPC-PQRCVNTQGGFECHCYPNYDL-------VD-GECVEPVDPCFRANCEYQCQ 379
C P C P RC++ G+ C C + L +D EC PC CE
Sbjct: 482 CQRNPQVCGPGRCISRPSGYTCACDSGFRLSPQGTRCIDVDECRRVPPPCAPGRCEN--- 538
Query: 380 PLNQTSYLCVCAEGFAPIPH--------EPHRCQMFCNQTACPADCDPNTQAS--CECPE 429
+ S+ CVC GF P E HR C+ C NT S C CP
Sbjct: 539 --SPGSFRCVCGPGFRAGPRAAECLDVDECHRVPPPCDLGRC-----ENTPGSFLCVCPA 591
Query: 430 GY-ILDDGFICTDIDEC-ENGGFCS-GVCHNLPGTFECICGPDSALARHIGTDCDSGKVD 486
GY G C D+DEC ++ G C G C NLPG+F C+C A G+ C+ +
Sbjct: 592 GYQAAPHGASCQDVDECTQSPGLCGRGACKNLPGSFRCVCP-----AGFRGSACE----E 642
Query: 487 GGDSGSGEPPP 497
D + EPPP
Sbjct: 643 DVDECAQEPPP 653
Score = 50.1 bits (118), Expect = 6e-06
Identities = 65/273 (23%), Positives = 93/273 (34%), Gaps = 54/273 (19%)
Query: 251 GCEHACNAIPGAPRCQCPAGAALQADGRSCT-ASATQSCNDLCEHFCVPNPDQPGSYSCM 309
G C +PG+ +C C G DGR C + ++ +C N + GS+ C+
Sbjct: 993 GAHAVCQNLPGSFQCLCDQGYEGARDGRHCVDVNECETLQGVCGAALCENVE--GSFLCV 1050
Query: 310 CETG--------------------YRLAADQHRCEDVDDCILEPSPCPQRCVNTQ----G 345
C + + Q V P P P+R + G
Sbjct: 1051 CPNSPEEFDPMTGRCVPPRTSAGTFPGSQPQAPASPVLPARPPPPPLPRRPSTPRQGPVG 1110
Query: 346 GFECHCYPNYDLVDG------------ECVEPVDPCFRANCEYQCQPLNQTS-YLCVCAE 392
CY + D EC V + + C Q P +T+ Y +C
Sbjct: 1111 SGRRECYFDTAAPDACDNILARNVTWQECCCTVGEGWGSGCRIQQCPGTETAEYQSLCPH 1170
Query: 393 G---FAP-----IPHEPHRCQMFCNQTACPADCDPNTQA--SCECPEGYILDDGFI-CTD 441
G AP + + CQ+F +Q C + NT SC C GY + C D
Sbjct: 1171 GRGYLAPSGDLSLRRDVDECQLFRDQV-CKSGVCVNTAPGYSCYCSNGYYYHTQRLECID 1229
Query: 442 IDEC--ENGGFCSGVCHNLPGTFECICGPDSAL 472
DEC E G C N G++ C C P L
Sbjct: 1230 NDECADEEPACEGGRCVNTVGSYHCTCEPPLVL 1262
Score = 49.7 bits (117), Expect = 7e-06
Identities = 44/145 (30%), Positives = 50/145 (34%), Gaps = 22/145 (15%)
Query: 225 TAPPGAVQGHWAREAPGAWDCSVENGGCEHACNA--IPGAPRCQ----CPAGA------- 271
TA P A AR C G C PG + CP G
Sbjct: 1120 TAAPDACDNILARNVTWQECCCTVGEGWGSGCRIQQCPGTETAEYQSLCPHGRGYLAPSG 1179
Query: 272 --ALQADGRSCTASATQSCNDLCEHFCVPNPDQPGSYSCMCETGYRLAADQHRCEDVDDC 329
+L+ D C Q C CV PG YSC C GY + C D D+C
Sbjct: 1180 DLSLRRDVDECQLFRDQVCKS---GVCVNTA--PG-YSCYCSNGYYYHTQRLECIDNDEC 1233
Query: 330 ILEPSPCP-QRCVNTQGGFECHCYP 353
E C RCVNT G + C C P
Sbjct: 1234 ADEEPACEGGRCVNTVGSYHCTCEP 1258
Score = 48.9 bits (115), Expect = 1e-05
Identities = 38/118 (32%), Positives = 54/118 (45%), Gaps = 21/118 (17%)
Query: 298 PNPDQP---GSYS-CMCETGYRLAADQHRCEDVDDCILEPSPCPQRCVNTQGGFECHCYP 353
P P++P GSY+ + E L A++ C +D C RCV GF C C+
Sbjct: 1443 PEPEEPPEGGSYAGSLAEPYEELEAEE--CGILDGCT------NGRCVRVPEGFTCRCFD 1494
Query: 354 NY--DLVDGECVEPVDPCFRANCE----YQCQPLN-QTSYLCVCAEGFAPIPHEPHRC 404
Y D+ CV+ ++ C A + LN S+ C+C GFAP H+PH C
Sbjct: 1495 GYRLDMTRMACVD-INECDEAEAASPLCVNARCLNTDGSFRCICRPGFAP-THQPHHC 1550
Score = 45.4 bits (106), Expect = 1e-04
Identities = 59/204 (28%), Positives = 82/204 (40%), Gaps = 30/204 (14%)
Query: 202 ADFQALPVGSSAAVAPLGLQLMCTAPPGAVQGHWAREAPGAWDCSVENGGCEHACNAIPG 261
AD +A+ +AA A A + ++ +A G C E G E A + +PG
Sbjct: 180 ADAEAVARAEAAARAEAAAPYTVLAQSAPREDGYS-DASGFGYCFRELRGGECA-SPLPG 237
Query: 262 APRCQ-CPAGAALQADGRSCTASATQSCND-LCEHFCVPNPDQPGSYSCMCETGYRLAAD 319
+ C GA L C Q C++ L V PD P C TG+
Sbjct: 238 LRTQEVCCRGAGLAWGVHDC-----QLCSERLGNSERVSAPDGP------CPTGFERVNG 286
Query: 320 QHRCEDVDDCILEPSPCPQRCVNTQGGFECHCYPNYDLVD---GECV------EPVDPCF 370
CEDVD+C C NT+GG+ C C P+ L+D C+ E PCF
Sbjct: 287 S--CEDVDECATGGRCQHGECANTRGGYTCVC-PDGFLLDSSRSSCISQHVISEAKGPCF 343
Query: 371 RANCEYQCQ-PL--NQTSYLCVCA 391
R + C P+ N T +C C+
Sbjct: 344 RVLRDGGCSLPILRNITKQICCCS 367
Score = 45.4 bits (106), Expect = 1e-04
Identities = 38/119 (31%), Positives = 52/119 (43%), Gaps = 8/119 (6%)
Query: 369 CFRANCEYQC-QPLNQTSYLCVCAEGFAPIPHEPHRCQMFCNQTACPADCDPNTQASCEC 427
CFR +C PL VC G A + H CQ+ C++ + + + C
Sbjct: 222 CFRELRGGECASPLPGLRTQEVCCRG-AGLAWGVHDCQL-CSERL--GNSERVSAPDGPC 277
Query: 428 PEGYILDDGFICTDIDECENGGFCS-GVCHNLPGTFECICGPDSALARHIGTDCDSGKV 485
P G+ +G C D+DEC GG C G C N G + C+C PD L + C S V
Sbjct: 278 PTGFERVNGS-CEDVDECATGGRCQHGECANTRGGYTCVC-PDGFLLDSSRSSCISQHV 334
Score = 40.4 bits (93), Expect = 0.004
Identities = 57/241 (23%), Positives = 77/241 (31%), Gaps = 40/241 (16%)
Query: 265 CQCPAGAALQADGRSCTASATQSCNDLCEHFCVP--NPDQPGSYSCMCETGYRLAADQHR 322
C C G A D C A + LC P +P +PG + E G L
Sbjct: 1308 CCCLYGEAWGMDCALCPAQDSDDFEALCNVLRPPAYSPPRPGGFGLPYEYGPDLGPPYQG 1367
Query: 323 CEDVDDCILEPS-------PCPQRCVNTQGGFECHCYPNYDLVD--------GECVEPVD 367
+ P+ P P + + P +D+ D GE P
Sbjct: 1368 LPYGPELYPPPALPYDPYPPPPGPFARREAPYGA---PRFDMPDFEDDGGPYGESEAPAP 1424
Query: 368 PCFRANCEYQC-----------QPLNQTSYLCVCAEGFAPIPHEPHRCQMFCNQTACPAD 416
P Y+ +P SY AE + + E C C
Sbjct: 1425 PGPGTRWPYRSRDTRRSFPEPEEPPEGGSYAGSLAEPYEELEAEECGILDGCTNGRCVRV 1484
Query: 417 CDPNTQASCECPEGYILD-DGFICTDIDECENGGFCSGVCHNL-----PGTFECICGPDS 470
+ T C C +GY LD C DI+EC+ S +C N G+F CIC P
Sbjct: 1485 PEGFT---CRCFDGYRLDMTRMACVDINECDEAEAASPLCVNARCLNTDGSFRCICRPGF 1541
Query: 471 A 471
A
Sbjct: 1542 A 1542
Score = 36.2 bits (82), Expect = 0.084
Identities = 21/86 (24%), Positives = 34/86 (39%), Gaps = 6/86 (6%)
Query: 242 AWDCSVENGGCEHACNAIPGAPRCQCPAGAALQADGRSCT----ASATQSCNDLCEHFCV 297
A +C + +G C +P C+C G L +C ++ + LC +
Sbjct: 1467 AEECGILDGCTNGRCVRVPEGFTCRCFDGYRLDMTRMACVDINECDEAEAASPLCVNARC 1526
Query: 298 PNPDQPGSYSCMCETGYRLAADQHRC 323
N D GS+ C+C G+ H C
Sbjct: 1527 LNTD--GSFRCICRPGFAPTHQPHHC 1550
Score = 32.7 bits (73), Expect = 0.93
Identities = 27/102 (26%), Positives = 39/102 (38%), Gaps = 20/102 (19%)
Query: 244 DCSVENGGCEHA-CNAIPGAPRCQCPAGAALQADGRSCTASATQSCND------------ 290
+C+ E CE C G+ C C L R C ++ +QS +D
Sbjct: 1232 ECADEEPACEGGRCVNTVGSYHCTCEPPLVLDGSQRRCVSNESQSLDDNLGVCWQEVGAD 1291
Query: 291 -LCEHFCVPNPDQPGSYS-CMCETGYRLAADQHRC--EDVDD 328
+C H P D+ +Y+ C C G D C +D DD
Sbjct: 1292 LVCSH---PRLDRQATYTECCCLYGEAWGMDCALCPAQDSDD 1330
Score = 30.4 bits (67), Expect = 4.6
Identities = 22/72 (30%), Positives = 33/72 (45%), Gaps = 8/72 (11%)
Query: 326 VDDCILEPSPCPQRCVNTQ--GGFECHCYPNYDLVDGECVEPVDPCFRAN-CEYQCQPLN 382
V DC L C +R N++ + C ++ V+G C E VD C C++
Sbjct: 254 VHDCQL----CSERLGNSERVSAPDGPCPTGFERVNGSC-EDVDECATGGRCQHGECANT 308
Query: 383 QTSYLCVCAEGF 394
+ Y CVC +GF
Sbjct: 309 RGGYTCVCPDGF 320
>gi|110347412 latent transforming growth factor beta binding protein
4 isoform b [Homo sapiens]
Length = 1587
Score = 106 bits (264), Expect = 7e-23
Identities = 90/317 (28%), Positives = 117/317 (36%), Gaps = 76/317 (23%)
Query: 210 GSSAAVAPLGLQLMCTAPPGAVQGHWAREAPGAWDCSVENGGCEH-ACNAIPGAPRCQCP 268
GS V P G Q AP GA +C+ G C AC +PG+ RC CP
Sbjct: 613 GSFLCVCPAGYQ---AAPHGA-------SCQDVDECTQSPGLCGRGACKNLPGSFRCVCP 662
Query: 269 AG---AALQADGRSCTASATQSCNDLCEHFCVPNPDQPGSYSCMCETGYRLAADQHRCED 325
AG +A + D C C++ GS+ C C G+R C+D
Sbjct: 663 AGFRGSACEEDVDECAQEPPPCGPGRCDNTA-------GSFHCACPAGFRSRGPGAPCQD 715
Query: 326 VDDCILEPSPCPQ-RCVNTQGGFECHCYPNY--DLVDGECVE----------PVDPCFRA 372
VD+C P PC RC NT+G F+C C + + EC + P C +
Sbjct: 716 VDECARSPPPCTYGRCENTEGSFQCVCPMGFQPNTAGSECEDVDECENHLACPGQECVNS 775
Query: 373 NCEYQCQPL--------------------------------NQTSYLCVCAEGFAPIPHE 400
+QC+ + S+ C CA G+
Sbjct: 776 PGSFQCRTCPSGHHLHRGRCTDVDECSSGAPPCGPHGHCTNTEGSFRCSCAPGYRAPSGR 835
Query: 401 PHRCQMFCNQTACPADCDP-----NTQAS--CECPEGYILDD-GFICTDIDECENGGFC- 451
P C N+ C P NT S C C GY G C D+DEC C
Sbjct: 836 PGPCADV-NECLEGDFCFPHGECLNTDGSFACTCAPGYRPGPRGASCLDVDECSEEDLCQ 894
Query: 452 SGVCHNLPGTFECICGP 468
SG+C N G+FECIC P
Sbjct: 895 SGICTNTDGSFECICPP 911
Score = 99.0 bits (245), Expect = 1e-20
Identities = 93/302 (30%), Positives = 112/302 (37%), Gaps = 73/302 (24%)
Query: 256 CNAIPGAPRCQCPAGAALQADGRSCTASATQSCNDLCEHFCVPNP-------DQPGSYSC 308
C + P C C +G L G C D+ E VP P + PGS+ C
Sbjct: 524 CISRPSGYTCACDSGFRLSPQGTRCI--------DVDECRRVPPPCAPGRCENSPGSFRC 575
Query: 309 MCETGYRLAADQHRCEDVDDCILEPSPCP-QRCVNTQGGFECHCYPNYDLV-DGECVEPV 366
+C G+R C DVD+C P PC RC NT G F C C Y G + V
Sbjct: 576 VCGPGFRAGPRAAECLDVDECHRVPPPCDLGRCENTPGSFLCVCPAGYQAAPHGASCQDV 635
Query: 367 DPCFRAN--CEYQCQPLNQTSYLCVCAEGF--------------APIPHEPHRCQMFCN- 409
D C ++ C S+ CVC GF P P P RC
Sbjct: 636 DECTQSPGLCGRGACKNLPGSFRCVCPAGFRGSACEEDVDECAQEPPPCGPGRCDNTAGS 695
Query: 410 -QTACPA------------DCD--------------PNTQAS--CECPEGYILDD-GFIC 439
ACPA D D NT+ S C CP G+ + G C
Sbjct: 696 FHCACPAGFRSRGPGAPCQDVDECARSPPPCTYGRCENTEGSFQCVCPMGFQPNTAGSEC 755
Query: 440 TDIDECENGGFCSG-VCHNLPGTFEC-ICGPDSALARHIGTDCDSGKVDGGDSGSGEPPP 497
D+DECEN C G C N PG+F+C C L R TD D + SG PP
Sbjct: 756 EDVDECENHLACPGQECVNSPGSFQCRTCPSGHHLHRGRCTDVD-------ECSSGAPPC 808
Query: 498 SP 499
P
Sbjct: 809 GP 810
Score = 99.0 bits (245), Expect = 1e-20
Identities = 79/233 (33%), Positives = 98/233 (42%), Gaps = 29/233 (12%)
Query: 256 CNAIPGAPRCQCPAGAALQADGRSCTASATQSCNDLCEHFCVPNPD---QPGSYSCMCET 312
C G+ RC C G + GR + C L FC P+ + GS++C C
Sbjct: 814 CTNTEGSFRCSCAPGYRAPS-GRPGPCADVNEC--LEGDFCFPHGECLNTDGSFACTCAP 870
Query: 313 GYRLAADQHRCEDVDDCILEPSPCPQRCVNTQGGFECHCYPNY----DLVDGECVEPVDP 368
GYR C DVD+C E C NT G FEC C P + DL C++ VD
Sbjct: 871 GYRPGPRGASCLDVDECSEEDLCQSGICTNTDGSFECICPPGHRAGPDL--ASCLD-VDE 927
Query: 369 CFR---ANCEYQCQPLNQTSYLCV--CAEGFAPIPH----EPHRCQMFCNQTACPADCDP 419
C A C Q + SY CV C G+ P + CQ + C A
Sbjct: 928 CRERGPALCGSQRCENSPGSYRCVRDCDPGYHAGPEGTCDDVDECQEY-GPEICGAQRCE 986
Query: 420 NTQASCE----CPEGYILDDGFICTDIDECENGGFCS--GVCHNLPGTFECIC 466
NT S C GY G C D+DEC N FC VC NLPG+F+C+C
Sbjct: 987 NTPGSYRCTPACDPGYQPTPGGGCQDVDECRNRSFCGAHAVCQNLPGSFQCLC 1039
Score = 87.8 bits (216), Expect = 2e-17
Identities = 84/307 (27%), Positives = 110/307 (35%), Gaps = 61/307 (19%)
Query: 224 CTAPPGAVQGHWAREAPGAWDCSVENGGCEHACNAIPGAPRCQCPAGAALQADGRSCTAS 283
CT PG G +CS E+ C G+ C CP G D SC
Sbjct: 866 CTCAPGYRPGPRGASCLDVDECSEEDLCQSGICTNTDGSFECICPPGHRAGPDLASCL-- 923
Query: 284 ATQSCNDLCEHFCVPN--PDQPGSYSCM--CETGYRLAADQHRCEDVDDC-ILEPSPC-P 337
C + C + PGSY C+ C+ GY A + C+DVD+C P C
Sbjct: 924 DVDECRERGPALCGSQRCENSPGSYRCVRDCDPGYH-AGPEGTCDDVDECQEYGPEICGA 982
Query: 338 QRCVNTQGGFEC--HCYPNYDLVDGECVEPVDPCFRANCEYQCQPLNQTSYLCVCAEGFA 395
QRC NT G + C C P Y G + VD C
Sbjct: 983 QRCENTPGSYRCTPACDPGYQPTPGGGCQDVDEC-------------------------- 1016
Query: 396 PIPHEPHRCQMFCNQTACPADCDPNTQASCECPEGYI-LDDGFICTDIDECEN-GGFC-S 452
R + FC A + + Q C C +GY DG C D++ECE G C +
Sbjct: 1017 -------RNRSFCGAHAVCQNLPGSFQ--CLCDQGYEGARDGRHCVDVNECETLQGVCGA 1067
Query: 453 GVCHNLPGTFECICGP-----DSALARHIGTDCDSGKVDGGDSGS-------GEPPPSPT 500
+C N+ G+F C+C D R + +G G + PPP P
Sbjct: 1068 ALCENVEGSFLCVCPNSPEEFDPMTGRCVPPRTSAGTFPGSQPQAPASPVLPARPPPPPL 1127
Query: 501 PGSTLTP 507
P TP
Sbjct: 1128 PRRPSTP 1134
Score = 77.4 bits (189), Expect = 3e-14
Identities = 62/191 (32%), Positives = 79/191 (41%), Gaps = 41/191 (21%)
Query: 329 CILEPSPC-PQRCVNTQGGFECHCYPNYDL-------VD-GECVEPVDPCFRANCEYQCQ 379
C P C P RC++ G+ C C + L +D EC PC CE
Sbjct: 512 CQRNPQVCGPGRCISRPSGYTCACDSGFRLSPQGTRCIDVDECRRVPPPCAPGRCEN--- 568
Query: 380 PLNQTSYLCVCAEGFAPIPH--------EPHRCQMFCNQTACPADCDPNTQAS--CECPE 429
+ S+ CVC GF P E HR C+ C NT S C CP
Sbjct: 569 --SPGSFRCVCGPGFRAGPRAAECLDVDECHRVPPPCDLGRC-----ENTPGSFLCVCPA 621
Query: 430 GY-ILDDGFICTDIDEC-ENGGFCS-GVCHNLPGTFECICGPDSALARHIGTDCDSGKVD 486
GY G C D+DEC ++ G C G C NLPG+F C+C A G+ C+ +
Sbjct: 622 GYQAAPHGASCQDVDECTQSPGLCGRGACKNLPGSFRCVCP-----AGFRGSACE----E 672
Query: 487 GGDSGSGEPPP 497
D + EPPP
Sbjct: 673 DVDECAQEPPP 683
Score = 50.1 bits (118), Expect = 6e-06
Identities = 65/273 (23%), Positives = 93/273 (34%), Gaps = 54/273 (19%)
Query: 251 GCEHACNAIPGAPRCQCPAGAALQADGRSCT-ASATQSCNDLCEHFCVPNPDQPGSYSCM 309
G C +PG+ +C C G DGR C + ++ +C N + GS+ C+
Sbjct: 1023 GAHAVCQNLPGSFQCLCDQGYEGARDGRHCVDVNECETLQGVCGAALCENVE--GSFLCV 1080
Query: 310 CETG--------------------YRLAADQHRCEDVDDCILEPSPCPQRCVNTQ----G 345
C + + Q V P P P+R + G
Sbjct: 1081 CPNSPEEFDPMTGRCVPPRTSAGTFPGSQPQAPASPVLPARPPPPPLPRRPSTPRQGPVG 1140
Query: 346 GFECHCYPNYDLVDG------------ECVEPVDPCFRANCEYQCQPLNQTS-YLCVCAE 392
CY + D EC V + + C Q P +T+ Y +C
Sbjct: 1141 SGRRECYFDTAAPDACDNILARNVTWQECCCTVGEGWGSGCRIQQCPGTETAEYQSLCPH 1200
Query: 393 G---FAP-----IPHEPHRCQMFCNQTACPADCDPNTQA--SCECPEGYILDDGFI-CTD 441
G AP + + CQ+F +Q C + NT SC C GY + C D
Sbjct: 1201 GRGYLAPSGDLSLRRDVDECQLFRDQV-CKSGVCVNTAPGYSCYCSNGYYYHTQRLECID 1259
Query: 442 IDEC--ENGGFCSGVCHNLPGTFECICGPDSAL 472
DEC E G C N G++ C C P L
Sbjct: 1260 NDECADEEPACEGGRCVNTVGSYHCTCEPPLVL 1292
Score = 49.7 bits (117), Expect = 7e-06
Identities = 44/145 (30%), Positives = 50/145 (34%), Gaps = 22/145 (15%)
Query: 225 TAPPGAVQGHWAREAPGAWDCSVENGGCEHACNA--IPGAPRCQ----CPAGA------- 271
TA P A AR C G C PG + CP G
Sbjct: 1150 TAAPDACDNILARNVTWQECCCTVGEGWGSGCRIQQCPGTETAEYQSLCPHGRGYLAPSG 1209
Query: 272 --ALQADGRSCTASATQSCNDLCEHFCVPNPDQPGSYSCMCETGYRLAADQHRCEDVDDC 329
+L+ D C Q C CV PG YSC C GY + C D D+C
Sbjct: 1210 DLSLRRDVDECQLFRDQVCKS---GVCVNTA--PG-YSCYCSNGYYYHTQRLECIDNDEC 1263
Query: 330 ILEPSPCP-QRCVNTQGGFECHCYP 353
E C RCVNT G + C C P
Sbjct: 1264 ADEEPACEGGRCVNTVGSYHCTCEP 1288
Score = 48.9 bits (115), Expect = 1e-05
Identities = 38/118 (32%), Positives = 54/118 (45%), Gaps = 21/118 (17%)
Query: 298 PNPDQP---GSYS-CMCETGYRLAADQHRCEDVDDCILEPSPCPQRCVNTQGGFECHCYP 353
P P++P GSY+ + E L A++ C +D C RCV GF C C+
Sbjct: 1473 PEPEEPPEGGSYAGSLAEPYEELEAEE--CGILDGCT------NGRCVRVPEGFTCRCFD 1524
Query: 354 NY--DLVDGECVEPVDPCFRANCE----YQCQPLN-QTSYLCVCAEGFAPIPHEPHRC 404
Y D+ CV+ ++ C A + LN S+ C+C GFAP H+PH C
Sbjct: 1525 GYRLDMTRMACVD-INECDEAEAASPLCVNARCLNTDGSFRCICRPGFAP-THQPHHC 1580
Score = 45.4 bits (106), Expect = 1e-04
Identities = 59/204 (28%), Positives = 82/204 (40%), Gaps = 30/204 (14%)
Query: 202 ADFQALPVGSSAAVAPLGLQLMCTAPPGAVQGHWAREAPGAWDCSVENGGCEHACNAIPG 261
AD +A+ +AA A A + ++ +A G C E G E A + +PG
Sbjct: 210 ADAEAVARAEAAARAEAAAPYTVLAQSAPREDGYS-DASGFGYCFRELRGGECA-SPLPG 267
Query: 262 APRCQ-CPAGAALQADGRSCTASATQSCND-LCEHFCVPNPDQPGSYSCMCETGYRLAAD 319
+ C GA L C Q C++ L V PD P C TG+
Sbjct: 268 LRTQEVCCRGAGLAWGVHDC-----QLCSERLGNSERVSAPDGP------CPTGFERVNG 316
Query: 320 QHRCEDVDDCILEPSPCPQRCVNTQGGFECHCYPNYDLVD---GECV------EPVDPCF 370
CEDVD+C C NT+GG+ C C P+ L+D C+ E PCF
Sbjct: 317 S--CEDVDECATGGRCQHGECANTRGGYTCVC-PDGFLLDSSRSSCISQHVISEAKGPCF 373
Query: 371 RANCEYQCQ-PL--NQTSYLCVCA 391
R + C P+ N T +C C+
Sbjct: 374 RVLRDGGCSLPILRNITKQICCCS 397
Score = 45.4 bits (106), Expect = 1e-04
Identities = 38/119 (31%), Positives = 52/119 (43%), Gaps = 8/119 (6%)
Query: 369 CFRANCEYQC-QPLNQTSYLCVCAEGFAPIPHEPHRCQMFCNQTACPADCDPNTQASCEC 427
CFR +C PL VC G A + H CQ+ C++ + + + C
Sbjct: 252 CFRELRGGECASPLPGLRTQEVCCRG-AGLAWGVHDCQL-CSERL--GNSERVSAPDGPC 307
Query: 428 PEGYILDDGFICTDIDECENGGFCS-GVCHNLPGTFECICGPDSALARHIGTDCDSGKV 485
P G+ +G C D+DEC GG C G C N G + C+C PD L + C S V
Sbjct: 308 PTGFERVNGS-CEDVDECATGGRCQHGECANTRGGYTCVC-PDGFLLDSSRSSCISQHV 364
Score = 40.4 bits (93), Expect = 0.004
Identities = 57/241 (23%), Positives = 77/241 (31%), Gaps = 40/241 (16%)
Query: 265 CQCPAGAALQADGRSCTASATQSCNDLCEHFCVP--NPDQPGSYSCMCETGYRLAADQHR 322
C C G A D C A + LC P +P +PG + E G L
Sbjct: 1338 CCCLYGEAWGMDCALCPAQDSDDFEALCNVLRPPAYSPPRPGGFGLPYEYGPDLGPPYQG 1397
Query: 323 CEDVDDCILEPS-------PCPQRCVNTQGGFECHCYPNYDLVD--------GECVEPVD 367
+ P+ P P + + P +D+ D GE P
Sbjct: 1398 LPYGPELYPPPALPYDPYPPPPGPFARREAPYGA---PRFDMPDFEDDGGPYGESEAPAP 1454
Query: 368 PCFRANCEYQC-----------QPLNQTSYLCVCAEGFAPIPHEPHRCQMFCNQTACPAD 416
P Y+ +P SY AE + + E C C
Sbjct: 1455 PGPGTRWPYRSRDTRRSFPEPEEPPEGGSYAGSLAEPYEELEAEECGILDGCTNGRCVRV 1514
Query: 417 CDPNTQASCECPEGYILD-DGFICTDIDECENGGFCSGVCHNL-----PGTFECICGPDS 470
+ T C C +GY LD C DI+EC+ S +C N G+F CIC P
Sbjct: 1515 PEGFT---CRCFDGYRLDMTRMACVDINECDEAEAASPLCVNARCLNTDGSFRCICRPGF 1571
Query: 471 A 471
A
Sbjct: 1572 A 1572
Score = 36.2 bits (82), Expect = 0.084
Identities = 21/86 (24%), Positives = 34/86 (39%), Gaps = 6/86 (6%)
Query: 242 AWDCSVENGGCEHACNAIPGAPRCQCPAGAALQADGRSCT----ASATQSCNDLCEHFCV 297
A +C + +G C +P C+C G L +C ++ + LC +
Sbjct: 1497 AEECGILDGCTNGRCVRVPEGFTCRCFDGYRLDMTRMACVDINECDEAEAASPLCVNARC 1556
Query: 298 PNPDQPGSYSCMCETGYRLAADQHRC 323
N D GS+ C+C G+ H C
Sbjct: 1557 LNTD--GSFRCICRPGFAPTHQPHHC 1580
Score = 32.7 bits (73), Expect = 0.93
Identities = 27/102 (26%), Positives = 39/102 (38%), Gaps = 20/102 (19%)
Query: 244 DCSVENGGCEHA-CNAIPGAPRCQCPAGAALQADGRSCTASATQSCND------------ 290
+C+ E CE C G+ C C L R C ++ +QS +D
Sbjct: 1262 ECADEEPACEGGRCVNTVGSYHCTCEPPLVLDGSQRRCVSNESQSLDDNLGVCWQEVGAD 1321
Query: 291 -LCEHFCVPNPDQPGSYS-CMCETGYRLAADQHRC--EDVDD 328
+C H P D+ +Y+ C C G D C +D DD
Sbjct: 1322 LVCSH---PRLDRQATYTECCCLYGEAWGMDCALCPAQDSDD 1360
Score = 30.4 bits (67), Expect = 4.6
Identities = 22/72 (30%), Positives = 33/72 (45%), Gaps = 8/72 (11%)
Query: 326 VDDCILEPSPCPQRCVNTQ--GGFECHCYPNYDLVDGECVEPVDPCFRAN-CEYQCQPLN 382
V DC L C +R N++ + C ++ V+G C E VD C C++
Sbjct: 284 VHDCQL----CSERLGNSERVSAPDGPCPTGFERVNGSC-EDVDECATGGRCQHGECANT 338
Query: 383 QTSYLCVCAEGF 394
+ Y CVC +GF
Sbjct: 339 RGGYTCVCPDGF 350
>gi|110347431 latent transforming growth factor beta binding protein
4 isoform a [Homo sapiens]
Length = 1624
Score = 106 bits (264), Expect = 7e-23
Identities = 90/317 (28%), Positives = 117/317 (36%), Gaps = 76/317 (23%)
Query: 210 GSSAAVAPLGLQLMCTAPPGAVQGHWAREAPGAWDCSVENGGCEH-ACNAIPGAPRCQCP 268
GS V P G Q AP GA +C+ G C AC +PG+ RC CP
Sbjct: 650 GSFLCVCPAGYQ---AAPHGA-------SCQDVDECTQSPGLCGRGACKNLPGSFRCVCP 699
Query: 269 AG---AALQADGRSCTASATQSCNDLCEHFCVPNPDQPGSYSCMCETGYRLAADQHRCED 325
AG +A + D C C++ GS+ C C G+R C+D
Sbjct: 700 AGFRGSACEEDVDECAQEPPPCGPGRCDNTA-------GSFHCACPAGFRSRGPGAPCQD 752
Query: 326 VDDCILEPSPCPQ-RCVNTQGGFECHCYPNY--DLVDGECVE----------PVDPCFRA 372
VD+C P PC RC NT+G F+C C + + EC + P C +
Sbjct: 753 VDECARSPPPCTYGRCENTEGSFQCVCPMGFQPNTAGSECEDVDECENHLACPGQECVNS 812
Query: 373 NCEYQCQPL--------------------------------NQTSYLCVCAEGFAPIPHE 400
+QC+ + S+ C CA G+
Sbjct: 813 PGSFQCRTCPSGHHLHRGRCTDVDECSSGAPPCGPHGHCTNTEGSFRCSCAPGYRAPSGR 872
Query: 401 PHRCQMFCNQTACPADCDP-----NTQAS--CECPEGYILDD-GFICTDIDECENGGFC- 451
P C N+ C P NT S C C GY G C D+DEC C
Sbjct: 873 PGPCADV-NECLEGDFCFPHGECLNTDGSFACTCAPGYRPGPRGASCLDVDECSEEDLCQ 931
Query: 452 SGVCHNLPGTFECICGP 468
SG+C N G+FECIC P
Sbjct: 932 SGICTNTDGSFECICPP 948
Score = 99.0 bits (245), Expect = 1e-20
Identities = 93/302 (30%), Positives = 112/302 (37%), Gaps = 73/302 (24%)
Query: 256 CNAIPGAPRCQCPAGAALQADGRSCTASATQSCNDLCEHFCVPNP-------DQPGSYSC 308
C + P C C +G L G C D+ E VP P + PGS+ C
Sbjct: 561 CISRPSGYTCACDSGFRLSPQGTRCI--------DVDECRRVPPPCAPGRCENSPGSFRC 612
Query: 309 MCETGYRLAADQHRCEDVDDCILEPSPCP-QRCVNTQGGFECHCYPNYDLV-DGECVEPV 366
+C G+R C DVD+C P PC RC NT G F C C Y G + V
Sbjct: 613 VCGPGFRAGPRAAECLDVDECHRVPPPCDLGRCENTPGSFLCVCPAGYQAAPHGASCQDV 672
Query: 367 DPCFRAN--CEYQCQPLNQTSYLCVCAEGF--------------APIPHEPHRCQMFCN- 409
D C ++ C S+ CVC GF P P P RC
Sbjct: 673 DECTQSPGLCGRGACKNLPGSFRCVCPAGFRGSACEEDVDECAQEPPPCGPGRCDNTAGS 732
Query: 410 -QTACPA------------DCD--------------PNTQAS--CECPEGYILDD-GFIC 439
ACPA D D NT+ S C CP G+ + G C
Sbjct: 733 FHCACPAGFRSRGPGAPCQDVDECARSPPPCTYGRCENTEGSFQCVCPMGFQPNTAGSEC 792
Query: 440 TDIDECENGGFCSG-VCHNLPGTFEC-ICGPDSALARHIGTDCDSGKVDGGDSGSGEPPP 497
D+DECEN C G C N PG+F+C C L R TD D + SG PP
Sbjct: 793 EDVDECENHLACPGQECVNSPGSFQCRTCPSGHHLHRGRCTDVD-------ECSSGAPPC 845
Query: 498 SP 499
P
Sbjct: 846 GP 847
Score = 99.0 bits (245), Expect = 1e-20
Identities = 79/233 (33%), Positives = 98/233 (42%), Gaps = 29/233 (12%)
Query: 256 CNAIPGAPRCQCPAGAALQADGRSCTASATQSCNDLCEHFCVPNPD---QPGSYSCMCET 312
C G+ RC C G + GR + C L FC P+ + GS++C C
Sbjct: 851 CTNTEGSFRCSCAPGYRAPS-GRPGPCADVNEC--LEGDFCFPHGECLNTDGSFACTCAP 907
Query: 313 GYRLAADQHRCEDVDDCILEPSPCPQRCVNTQGGFECHCYPNY----DLVDGECVEPVDP 368
GYR C DVD+C E C NT G FEC C P + DL C++ VD
Sbjct: 908 GYRPGPRGASCLDVDECSEEDLCQSGICTNTDGSFECICPPGHRAGPDL--ASCLD-VDE 964
Query: 369 CFR---ANCEYQCQPLNQTSYLCV--CAEGFAPIPH----EPHRCQMFCNQTACPADCDP 419
C A C Q + SY CV C G+ P + CQ + C A
Sbjct: 965 CRERGPALCGSQRCENSPGSYRCVRDCDPGYHAGPEGTCDDVDECQEY-GPEICGAQRCE 1023
Query: 420 NTQASCE----CPEGYILDDGFICTDIDECENGGFCS--GVCHNLPGTFECIC 466
NT S C GY G C D+DEC N FC VC NLPG+F+C+C
Sbjct: 1024 NTPGSYRCTPACDPGYQPTPGGGCQDVDECRNRSFCGAHAVCQNLPGSFQCLC 1076
Score = 87.8 bits (216), Expect = 2e-17
Identities = 84/307 (27%), Positives = 110/307 (35%), Gaps = 61/307 (19%)
Query: 224 CTAPPGAVQGHWAREAPGAWDCSVENGGCEHACNAIPGAPRCQCPAGAALQADGRSCTAS 283
CT PG G +CS E+ C G+ C CP G D SC
Sbjct: 903 CTCAPGYRPGPRGASCLDVDECSEEDLCQSGICTNTDGSFECICPPGHRAGPDLASCL-- 960
Query: 284 ATQSCNDLCEHFCVPN--PDQPGSYSCM--CETGYRLAADQHRCEDVDDC-ILEPSPC-P 337
C + C + PGSY C+ C+ GY A + C+DVD+C P C
Sbjct: 961 DVDECRERGPALCGSQRCENSPGSYRCVRDCDPGYH-AGPEGTCDDVDECQEYGPEICGA 1019
Query: 338 QRCVNTQGGFEC--HCYPNYDLVDGECVEPVDPCFRANCEYQCQPLNQTSYLCVCAEGFA 395
QRC NT G + C C P Y G + VD C
Sbjct: 1020 QRCENTPGSYRCTPACDPGYQPTPGGGCQDVDEC-------------------------- 1053
Query: 396 PIPHEPHRCQMFCNQTACPADCDPNTQASCECPEGYI-LDDGFICTDIDECEN-GGFC-S 452
R + FC A + + Q C C +GY DG C D++ECE G C +
Sbjct: 1054 -------RNRSFCGAHAVCQNLPGSFQ--CLCDQGYEGARDGRHCVDVNECETLQGVCGA 1104
Query: 453 GVCHNLPGTFECICGP-----DSALARHIGTDCDSGKVDGGDSGS-------GEPPPSPT 500
+C N+ G+F C+C D R + +G G + PPP P
Sbjct: 1105 ALCENVEGSFLCVCPNSPEEFDPMTGRCVPPRTSAGTFPGSQPQAPASPVLPARPPPPPL 1164
Query: 501 PGSTLTP 507
P TP
Sbjct: 1165 PRRPSTP 1171
Score = 77.4 bits (189), Expect = 3e-14
Identities = 62/191 (32%), Positives = 79/191 (41%), Gaps = 41/191 (21%)
Query: 329 CILEPSPC-PQRCVNTQGGFECHCYPNYDL-------VD-GECVEPVDPCFRANCEYQCQ 379
C P C P RC++ G+ C C + L +D EC PC CE
Sbjct: 549 CQRNPQVCGPGRCISRPSGYTCACDSGFRLSPQGTRCIDVDECRRVPPPCAPGRCEN--- 605
Query: 380 PLNQTSYLCVCAEGFAPIPH--------EPHRCQMFCNQTACPADCDPNTQAS--CECPE 429
+ S+ CVC GF P E HR C+ C NT S C CP
Sbjct: 606 --SPGSFRCVCGPGFRAGPRAAECLDVDECHRVPPPCDLGRC-----ENTPGSFLCVCPA 658
Query: 430 GY-ILDDGFICTDIDEC-ENGGFCS-GVCHNLPGTFECICGPDSALARHIGTDCDSGKVD 486
GY G C D+DEC ++ G C G C NLPG+F C+C A G+ C+ +
Sbjct: 659 GYQAAPHGASCQDVDECTQSPGLCGRGACKNLPGSFRCVCP-----AGFRGSACE----E 709
Query: 487 GGDSGSGEPPP 497
D + EPPP
Sbjct: 710 DVDECAQEPPP 720
Score = 50.1 bits (118), Expect = 6e-06
Identities = 65/273 (23%), Positives = 93/273 (34%), Gaps = 54/273 (19%)
Query: 251 GCEHACNAIPGAPRCQCPAGAALQADGRSCT-ASATQSCNDLCEHFCVPNPDQPGSYSCM 309
G C +PG+ +C C G DGR C + ++ +C N + GS+ C+
Sbjct: 1060 GAHAVCQNLPGSFQCLCDQGYEGARDGRHCVDVNECETLQGVCGAALCENVE--GSFLCV 1117
Query: 310 CETG--------------------YRLAADQHRCEDVDDCILEPSPCPQRCVNTQ----G 345
C + + Q V P P P+R + G
Sbjct: 1118 CPNSPEEFDPMTGRCVPPRTSAGTFPGSQPQAPASPVLPARPPPPPLPRRPSTPRQGPVG 1177
Query: 346 GFECHCYPNYDLVDG------------ECVEPVDPCFRANCEYQCQPLNQTS-YLCVCAE 392
CY + D EC V + + C Q P +T+ Y +C
Sbjct: 1178 SGRRECYFDTAAPDACDNILARNVTWQECCCTVGEGWGSGCRIQQCPGTETAEYQSLCPH 1237
Query: 393 G---FAP-----IPHEPHRCQMFCNQTACPADCDPNTQA--SCECPEGYILDDGFI-CTD 441
G AP + + CQ+F +Q C + NT SC C GY + C D
Sbjct: 1238 GRGYLAPSGDLSLRRDVDECQLFRDQV-CKSGVCVNTAPGYSCYCSNGYYYHTQRLECID 1296
Query: 442 IDEC--ENGGFCSGVCHNLPGTFECICGPDSAL 472
DEC E G C N G++ C C P L
Sbjct: 1297 NDECADEEPACEGGRCVNTVGSYHCTCEPPLVL 1329
Score = 49.7 bits (117), Expect = 7e-06
Identities = 44/145 (30%), Positives = 50/145 (34%), Gaps = 22/145 (15%)
Query: 225 TAPPGAVQGHWAREAPGAWDCSVENGGCEHACNA--IPGAPRCQ----CPAGA------- 271
TA P A AR C G C PG + CP G
Sbjct: 1187 TAAPDACDNILARNVTWQECCCTVGEGWGSGCRIQQCPGTETAEYQSLCPHGRGYLAPSG 1246
Query: 272 --ALQADGRSCTASATQSCNDLCEHFCVPNPDQPGSYSCMCETGYRLAADQHRCEDVDDC 329
+L+ D C Q C CV PG YSC C GY + C D D+C
Sbjct: 1247 DLSLRRDVDECQLFRDQVCKS---GVCVNTA--PG-YSCYCSNGYYYHTQRLECIDNDEC 1300
Query: 330 ILEPSPCP-QRCVNTQGGFECHCYP 353
E C RCVNT G + C C P
Sbjct: 1301 ADEEPACEGGRCVNTVGSYHCTCEP 1325
Score = 48.9 bits (115), Expect = 1e-05
Identities = 38/118 (32%), Positives = 54/118 (45%), Gaps = 21/118 (17%)
Query: 298 PNPDQP---GSYS-CMCETGYRLAADQHRCEDVDDCILEPSPCPQRCVNTQGGFECHCYP 353
P P++P GSY+ + E L A++ C +D C RCV GF C C+
Sbjct: 1510 PEPEEPPEGGSYAGSLAEPYEELEAEE--CGILDGCT------NGRCVRVPEGFTCRCFD 1561
Query: 354 NY--DLVDGECVEPVDPCFRANCE----YQCQPLN-QTSYLCVCAEGFAPIPHEPHRC 404
Y D+ CV+ ++ C A + LN S+ C+C GFAP H+PH C
Sbjct: 1562 GYRLDMTRMACVD-INECDEAEAASPLCVNARCLNTDGSFRCICRPGFAP-THQPHHC 1617
Score = 45.4 bits (106), Expect = 1e-04
Identities = 59/204 (28%), Positives = 82/204 (40%), Gaps = 30/204 (14%)
Query: 202 ADFQALPVGSSAAVAPLGLQLMCTAPPGAVQGHWAREAPGAWDCSVENGGCEHACNAIPG 261
AD +A+ +AA A A + ++ +A G C E G E A + +PG
Sbjct: 247 ADAEAVARAEAAARAEAAAPYTVLAQSAPREDGYS-DASGFGYCFRELRGGECA-SPLPG 304
Query: 262 APRCQ-CPAGAALQADGRSCTASATQSCND-LCEHFCVPNPDQPGSYSCMCETGYRLAAD 319
+ C GA L C Q C++ L V PD P C TG+
Sbjct: 305 LRTQEVCCRGAGLAWGVHDC-----QLCSERLGNSERVSAPDGP------CPTGFERVNG 353
Query: 320 QHRCEDVDDCILEPSPCPQRCVNTQGGFECHCYPNYDLVD---GECV------EPVDPCF 370
CEDVD+C C NT+GG+ C C P+ L+D C+ E PCF
Sbjct: 354 S--CEDVDECATGGRCQHGECANTRGGYTCVC-PDGFLLDSSRSSCISQHVISEAKGPCF 410
Query: 371 RANCEYQCQ-PL--NQTSYLCVCA 391
R + C P+ N T +C C+
Sbjct: 411 RVLRDGGCSLPILRNITKQICCCS 434
Score = 45.4 bits (106), Expect = 1e-04
Identities = 38/119 (31%), Positives = 52/119 (43%), Gaps = 8/119 (6%)
Query: 369 CFRANCEYQC-QPLNQTSYLCVCAEGFAPIPHEPHRCQMFCNQTACPADCDPNTQASCEC 427
CFR +C PL VC G A + H CQ+ C++ + + + C
Sbjct: 289 CFRELRGGECASPLPGLRTQEVCCRG-AGLAWGVHDCQL-CSERL--GNSERVSAPDGPC 344
Query: 428 PEGYILDDGFICTDIDECENGGFCS-GVCHNLPGTFECICGPDSALARHIGTDCDSGKV 485
P G+ +G C D+DEC GG C G C N G + C+C PD L + C S V
Sbjct: 345 PTGFERVNGS-CEDVDECATGGRCQHGECANTRGGYTCVC-PDGFLLDSSRSSCISQHV 401
Score = 40.4 bits (93), Expect = 0.004
Identities = 57/241 (23%), Positives = 77/241 (31%), Gaps = 40/241 (16%)
Query: 265 CQCPAGAALQADGRSCTASATQSCNDLCEHFCVP--NPDQPGSYSCMCETGYRLAADQHR 322
C C G A D C A + LC P +P +PG + E G L
Sbjct: 1375 CCCLYGEAWGMDCALCPAQDSDDFEALCNVLRPPAYSPPRPGGFGLPYEYGPDLGPPYQG 1434
Query: 323 CEDVDDCILEPS-------PCPQRCVNTQGGFECHCYPNYDLVD--------GECVEPVD 367
+ P+ P P + + P +D+ D GE P
Sbjct: 1435 LPYGPELYPPPALPYDPYPPPPGPFARREAPYGA---PRFDMPDFEDDGGPYGESEAPAP 1491
Query: 368 PCFRANCEYQC-----------QPLNQTSYLCVCAEGFAPIPHEPHRCQMFCNQTACPAD 416
P Y+ +P SY AE + + E C C
Sbjct: 1492 PGPGTRWPYRSRDTRRSFPEPEEPPEGGSYAGSLAEPYEELEAEECGILDGCTNGRCVRV 1551
Query: 417 CDPNTQASCECPEGYILD-DGFICTDIDECENGGFCSGVCHNL-----PGTFECICGPDS 470
+ T C C +GY LD C DI+EC+ S +C N G+F CIC P
Sbjct: 1552 PEGFT---CRCFDGYRLDMTRMACVDINECDEAEAASPLCVNARCLNTDGSFRCICRPGF 1608
Query: 471 A 471
A
Sbjct: 1609 A 1609
Score = 36.2 bits (82), Expect = 0.084
Identities = 21/86 (24%), Positives = 34/86 (39%), Gaps = 6/86 (6%)
Query: 242 AWDCSVENGGCEHACNAIPGAPRCQCPAGAALQADGRSCT----ASATQSCNDLCEHFCV 297
A +C + +G C +P C+C G L +C ++ + LC +
Sbjct: 1534 AEECGILDGCTNGRCVRVPEGFTCRCFDGYRLDMTRMACVDINECDEAEAASPLCVNARC 1593
Query: 298 PNPDQPGSYSCMCETGYRLAADQHRC 323
N D GS+ C+C G+ H C
Sbjct: 1594 LNTD--GSFRCICRPGFAPTHQPHHC 1617
Score = 32.7 bits (73), Expect = 0.93
Identities = 27/102 (26%), Positives = 39/102 (38%), Gaps = 20/102 (19%)
Query: 244 DCSVENGGCEHA-CNAIPGAPRCQCPAGAALQADGRSCTASATQSCND------------ 290
+C+ E CE C G+ C C L R C ++ +QS +D
Sbjct: 1299 ECADEEPACEGGRCVNTVGSYHCTCEPPLVLDGSQRRCVSNESQSLDDNLGVCWQEVGAD 1358
Query: 291 -LCEHFCVPNPDQPGSYS-CMCETGYRLAADQHRC--EDVDD 328
+C H P D+ +Y+ C C G D C +D DD
Sbjct: 1359 LVCSH---PRLDRQATYTECCCLYGEAWGMDCALCPAQDSDD 1397
Score = 30.4 bits (67), Expect = 4.6
Identities = 22/72 (30%), Positives = 33/72 (45%), Gaps = 8/72 (11%)
Query: 326 VDDCILEPSPCPQRCVNTQ--GGFECHCYPNYDLVDGECVEPVDPCFRAN-CEYQCQPLN 382
V DC L C +R N++ + C ++ V+G C E VD C C++
Sbjct: 321 VHDCQL----CSERLGNSERVSAPDGPCPTGFERVNGSC-EDVDECATGGRCQHGECANT 375
Query: 383 QTSYLCVCAEGF 394
+ Y CVC +GF
Sbjct: 376 RGGYTCVCPDGF 387
>gi|190343004 EGF-containing fibulin-like extracellular matrix
protein 2 [Homo sapiens]
Length = 443
Score = 105 bits (263), Expect = 9e-23
Identities = 71/214 (33%), Positives = 98/214 (45%), Gaps = 47/214 (21%)
Query: 256 CNAIPGAPRCQCPAGAALQADGRSCTASATQSCNDLCEHFCVPNPDQPGSYSCMCETGYR 315
C+ +PG+ +C CP G + G C + C+H CV + PGS+ C CE G++
Sbjct: 140 CHNLPGSYQCTCPDG--YRKIGPEC-VDIDECRYRYCQHRCV---NLPGSFRCQCEPGFQ 193
Query: 316 LAADQHRCEDVDDCILEPSPCPQRCVNTQGGFECHCYPNYDL-VDGECVEPVDPCFRANC 374
L + C DV++C + +PC QRC N+ G F C C+ Y+L DG +D C +
Sbjct: 194 LGPNNRSCVDVNECDM-GAPCEQRCFNSYGTFLCRCHQGYELHRDGFSCSDIDEC--SYS 250
Query: 375 EYQCQPLNQTSYLCVCAEGFAPIPHEPHRCQMFCNQTACPADCDPNTQASCECPEGYILD 434
Y CQ Y CV +EP R SC CP+GY L
Sbjct: 251 SYLCQ------YRCV---------NEPGR-------------------FSCHCPQGYQLL 276
Query: 435 DGFICTDIDECENGGF-CS--GVCHNLPGTFECI 465
+C DIDECE+G CS C N G + C+
Sbjct: 277 ATRLCQDIDECESGAHQCSEAQTCVNFHGGYRCV 310
Score = 96.7 bits (239), Expect = 5e-20
Identities = 80/254 (31%), Positives = 106/254 (41%), Gaps = 21/254 (8%)
Query: 243 WDCSVENGGCEHACNAIPGAPRCQCPAGAALQADGRSCTASATQSCNDLCEHFCVPNPDQ 302
WD ++ + C IP A C+ G C + NDL P P
Sbjct: 45 WDPDSQHCRDVNECLTIPEA--CKGEMKCINHYGGYLCLPRSAAVINDLHGEG-PPPPVP 101
Query: 303 PGSYSCMCETGYRLAADQHRCEDVDDCILEPSPC--PQRCVNTQGGFECHCYPNYDLVDG 360
P + C GY DQ C DVD+C C Q C N G ++C C Y +
Sbjct: 102 PAQHPNPCPPGYE-PDDQDSCVDVDECAQALHDCRPSQDCHNLPGSYQCTCPDGYRKIGP 160
Query: 361 ECVEPVDPCFRANCEYQCQPLNQTSYLCVCAEGFAPIPHEPHRCQMFCNQTACPADCDPN 420
ECV+ +D C C+++C L S+ C C GF P+ +R + N+ A C+
Sbjct: 161 ECVD-IDECRYRYCQHRCVNL-PGSFRCQCEPGFQLGPN--NRSCVDVNECDMGAPCEQR 216
Query: 421 TQAS-----CECPEGYILD-DGFICTDIDECENGGF-CSGVCHNLPGTFECICGPD-SAL 472
S C C +GY L DGF C+DIDEC + C C N PG F C C L
Sbjct: 217 CFNSYGTFLCRCHQGYELHRDGFSCSDIDECSYSSYLCQYRCVNEPGRFSCHCPQGYQLL 276
Query: 473 ARHIGTD---CDSG 483
A + D C+SG
Sbjct: 277 ATRLCQDIDECESG 290
Score = 90.5 bits (223), Expect = 4e-18
Identities = 53/173 (30%), Positives = 70/173 (40%), Gaps = 23/173 (13%)
Query: 252 CEHACNAIPGAPRCQCPAGAALQADGRSCTASATQSCNDLCEHFCVPNPDQPGSYSCMCE 311
C+H C +PG+ RCQC G L + RSC CE C + G++ C C
Sbjct: 173 CQHRCVNLPGSFRCQCEPGFQLGPNNRSCVDVNECDMGAPCEQRCF---NSYGTFLCRCH 229
Query: 312 TGYRLAADQHRCEDVDDCILEPSPCPQRCVNTQGGFECHCYPNYDLVDGECVEPVDPCFR 371
GY L D C D+D+C C RCVN G F CHC Y L+ + +D C
Sbjct: 230 QGYELHRDGFSCSDIDECSYSSYLCQYRCVNEPGRFSCHCPQGYQLLATRLCQDIDEC-- 287
Query: 372 ANCEYQCQPLN-----QTSYLCV----CAEGFAPIPHEPHRCQMFCNQTACPA 415
+ +QC Y CV C E + + N+ CPA
Sbjct: 288 ESGAHQCSEAQTCVNFHGGYRCVDTNRCVEPYIQVSE---------NRCLCPA 331
Score = 73.9 bits (180), Expect = 4e-13
Identities = 63/196 (32%), Positives = 82/196 (41%), Gaps = 24/196 (12%)
Query: 301 DQPGSYSCMCETGYRLAADQHRCEDVDDCILEPSPCP--QRCVNTQGGFEC---HCYPNY 355
++P SY+ C GY D C DV++C+ P C +C+N GG+ C
Sbjct: 31 EEPDSYT-ECTDGYEWDPDSQHCRDVNECLTIPEACKGEMKCINHYGGYLCLPRSAAVIN 89
Query: 356 DLVDGECVEPVDPCFRAN-CEYQCQPLNQTSYLCVCAEGFAPIPHEPHRCQMFCNQTACP 414
DL PV P N C +P +Q S CV + A H+ Q
Sbjct: 90 DLHGEGPPPPVPPAQHPNPCPPGYEPDDQDS--CVDVDECAQALHDCRPSQ--------- 138
Query: 415 ADCDPNTQAS--CECPEGYILDDGFICTDIDECENGGFCSGVCHNLPGTFECICGPDSAL 472
DC N S C CP+GY G C DIDEC +C C NLPG+F C C P L
Sbjct: 139 -DCH-NLPGSYQCTCPDGY-RKIGPECVDIDECRYR-YCQHRCVNLPGSFRCQCEPGFQL 194
Query: 473 ARHIGTDCDSGKVDGG 488
+ + D + D G
Sbjct: 195 GPNNRSCVDVNECDMG 210
Score = 38.9 bits (89), Expect = 0.013
Identities = 43/173 (24%), Positives = 59/173 (34%), Gaps = 59/173 (34%)
Query: 244 DCSVENGGCEHACNAIPGAPRCQCPAGAALQADGRSCTASATQSCNDLCEHFCVPNPDQP 303
+CS + C++ C PG C CP G L AT+ C D+ E
Sbjct: 246 ECSYSSYLCQYRCVNEPGRFSCHCPQGYQL---------LATRLCQDIDE---------- 286
Query: 304 GSYSCMCETGYRLAADQHRCEDVDDCILEPSPCPQRCVNTQGGFECHCYPNYDLVDGECV 363
CE+G H+C + Q CVN GG+ C + CV
Sbjct: 287 ------CESG------AHQCSEA-----------QTCVNFHGGYRC-------VDTNRCV 316
Query: 364 EPVDPCFRANCEYQCQPLNQTSYLCVCAEGFAPIPHEPHRCQMFCNQTACPAD 416
EP C C N +C E + I HR ++ + PAD
Sbjct: 317 EPYIQVSENRC--LCPASNP-----LCREQPSSI---VHRYMTITSERSVPAD 359
>gi|169178458 PREDICTED: hemicentin 2 [Homo sapiens]
Length = 3874
Score = 104 bits (259), Expect = 3e-22
Identities = 90/330 (27%), Positives = 123/330 (37%), Gaps = 77/330 (23%)
Query: 244 DCSVENGGCEHACNAIPGAPRCQCPAGAALQADGRSCTASATQSCNDLCEHFCVPNP--- 300
+CS C HAC PG C CP G AL D R+C + D H C
Sbjct: 3446 ECSGGPSPCSHACLNAPGRFSCTCPTGFALAWDDRNC-RDVDECAWD--AHLCREGQRCV 3502
Query: 301 DQPGSYSCM--CETGYRLAADQHRCEDVDDCI--LEPSPCPQRCVNTQGGFECHCYPNYD 356
+ GSY C+ C G+R+ AD CEDVD+C+ L+ Q C NT GG C C Y
Sbjct: 3503 NLLGSYRCLPDCGPGFRV-ADGAGCEDVDECLEGLDDCHYNQLCENTPGGHRCSCPRGYR 3561
Query: 357 LVDGECVEPVDPCFRAN--------CEYQCQPLNQTSYLCVCAEG--------------- 393
+ P PC N C YQC L Q SY C+C G
Sbjct: 3562 MQG-----PSLPCLDVNECLQLPKACAYQCHNL-QGSYRCLCPPGQTLLRDGKACTSLER 3615
Query: 394 --------------------FAPIPHEPHRCQMFCNQTACPADCDPNTQASCECPEGYIL 433
+A IP + + + P ++ CP G+I
Sbjct: 3616 NGQNVTTVSHRGPLLPWLRPWASIPGTSYHAWV----SLRPGPMALSSVGRAWCPPGFIR 3671
Query: 434 DDGFICTDIDECENGGFCSGVCHNLPGTFECICGPDSAL------------ARHIGTDCD 481
+G +CTD+DEC C C N G+++C+C L +C
Sbjct: 3672 QNG-VCTDLDECRVRNLCQHACRNTEGSYQCLCPAGYRLLPSGKNCQDINECEEESIECG 3730
Query: 482 SGKVDGGDSGSGEPPPSPTPGSTLTPPAVG 511
G++ GS + +P P + P+ G
Sbjct: 3731 PGQMCFNTRGSYQCVDTPCPATYRQGPSPG 3760
Score = 100 bits (250), Expect = 3e-21
Identities = 72/230 (31%), Positives = 95/230 (41%), Gaps = 49/230 (21%)
Query: 267 CPAGAALQADGRSCTASATQSCNDL-CEHFCVPNPDQPGSYSCMCETGYRLAADQHRCED 325
CP G L + G C S C H C+ + PG +SC C TG+ LA D C D
Sbjct: 3428 CPEGFELDSQGAFCVDRDECSGGPSPCSHACL---NAPGRFSCTCPTGFALAWDDRNCRD 3484
Query: 326 VDDCILEPSPC--PQRCVNTQGGFEC--HCYPNYDLVDGECVEPVDPCFRA--NCEYQCQ 379
VD+C + C QRCVN G + C C P + + DG E VD C +C Y
Sbjct: 3485 VDECAWDAHLCREGQRCVNLLGSYRCLPDCGPGFRVADGAGCEDVDECLEGLDDCHY--- 3541
Query: 380 PLNQTSYLCVCAEGFAPIPHEPHRCQMFCNQTACPADCDPNTQASCECPEGYILDDGFI- 438
+ LC G HR C CP GY + +
Sbjct: 3542 -----NQLCENTPG-------GHR---------------------CSCPRGYRMQGPSLP 3568
Query: 439 CTDIDEC-ENGGFCSGVCHNLPGTFECICGPDSALARHIGTDCDSGKVDG 487
C D++EC + C+ CHNL G++ C+C P L R G C S + +G
Sbjct: 3569 CLDVNECLQLPKACAYQCHNLQGSYRCLCPPGQTLLRD-GKACTSLERNG 3617
Score = 43.1 bits (100), Expect = 7e-04
Identities = 29/88 (32%), Positives = 37/88 (42%), Gaps = 14/88 (15%)
Query: 244 DCSVENGGCEHACNAIPGAPRCQCPAGAALQADGRSCTASATQSCNDLCEHFCVPNPDQ- 302
+C V N C+HAC G+ +C CPAG L G++C Q N+ E P Q
Sbjct: 3681 ECRVRNL-CQHACRNTEGSYQCLCPAGYRLLPSGKNC-----QDINECEEESIECGPGQM 3734
Query: 303 ----PGSYSCM---CETGYRLAADQHRC 323
GSY C+ C YR C
Sbjct: 3735 CFNTRGSYQCVDTPCPATYRQGPSPGTC 3762
>gi|239749684 PREDICTED: hemicentin 2 [Homo sapiens]
Length = 5065
Score = 104 bits (259), Expect = 3e-22
Identities = 90/330 (27%), Positives = 123/330 (37%), Gaps = 77/330 (23%)
Query: 244 DCSVENGGCEHACNAIPGAPRCQCPAGAALQADGRSCTASATQSCNDLCEHFCVPNP--- 300
+CS C HAC PG C CP G AL D R+C + D H C
Sbjct: 4637 ECSGGPSPCSHACLNAPGRFSCTCPTGFALAWDDRNC-RDVDECAWD--AHLCREGQRCV 4693
Query: 301 DQPGSYSCM--CETGYRLAADQHRCEDVDDCI--LEPSPCPQRCVNTQGGFECHCYPNYD 356
+ GSY C+ C G+R+ AD CEDVD+C+ L+ Q C NT GG C C Y
Sbjct: 4694 NLLGSYRCLPDCGPGFRV-ADGAGCEDVDECLEGLDDCHYNQLCENTPGGHRCSCPRGYR 4752
Query: 357 LVDGECVEPVDPCFRAN--------CEYQCQPLNQTSYLCVCAEG--------------- 393
+ P PC N C YQC L Q SY C+C G
Sbjct: 4753 MQG-----PSLPCLDVNECLQLPKACAYQCHNL-QGSYRCLCPPGQTLLRDGKACTSLER 4806
Query: 394 --------------------FAPIPHEPHRCQMFCNQTACPADCDPNTQASCECPEGYIL 433
+A IP + + + P ++ CP G+I
Sbjct: 4807 NGQNVTTVSHRGPLLPWLRPWASIPGTSYHAWV----SLRPGPMALSSVGRAWCPPGFIR 4862
Query: 434 DDGFICTDIDECENGGFCSGVCHNLPGTFECICGPDSAL------------ARHIGTDCD 481
+G +CTD+DEC C C N G+++C+C L +C
Sbjct: 4863 QNG-VCTDLDECRVRNLCQHACRNTEGSYQCLCPAGYRLLPSGKNCQDINECEEESIECG 4921
Query: 482 SGKVDGGDSGSGEPPPSPTPGSTLTPPAVG 511
G++ GS + +P P + P+ G
Sbjct: 4922 PGQMCFNTRGSYQCVDTPCPATYRQGPSPG 4951
Score = 100 bits (250), Expect = 3e-21
Identities = 72/230 (31%), Positives = 95/230 (41%), Gaps = 49/230 (21%)
Query: 267 CPAGAALQADGRSCTASATQSCNDL-CEHFCVPNPDQPGSYSCMCETGYRLAADQHRCED 325
CP G L + G C S C H C+ + PG +SC C TG+ LA D C D
Sbjct: 4619 CPEGFELDSQGAFCVDRDECSGGPSPCSHACL---NAPGRFSCTCPTGFALAWDDRNCRD 4675
Query: 326 VDDCILEPSPC--PQRCVNTQGGFEC--HCYPNYDLVDGECVEPVDPCFRA--NCEYQCQ 379
VD+C + C QRCVN G + C C P + + DG E VD C +C Y
Sbjct: 4676 VDECAWDAHLCREGQRCVNLLGSYRCLPDCGPGFRVADGAGCEDVDECLEGLDDCHY--- 4732
Query: 380 PLNQTSYLCVCAEGFAPIPHEPHRCQMFCNQTACPADCDPNTQASCECPEGYILDDGFI- 438
+ LC G HR C CP GY + +
Sbjct: 4733 -----NQLCENTPG-------GHR---------------------CSCPRGYRMQGPSLP 4759
Query: 439 CTDIDEC-ENGGFCSGVCHNLPGTFECICGPDSALARHIGTDCDSGKVDG 487
C D++EC + C+ CHNL G++ C+C P L R G C S + +G
Sbjct: 4760 CLDVNECLQLPKACAYQCHNLQGSYRCLCPPGQTLLRD-GKACTSLERNG 4808
Score = 43.1 bits (100), Expect = 7e-04
Identities = 29/88 (32%), Positives = 37/88 (42%), Gaps = 14/88 (15%)
Query: 244 DCSVENGGCEHACNAIPGAPRCQCPAGAALQADGRSCTASATQSCNDLCEHFCVPNPDQ- 302
+C V N C+HAC G+ +C CPAG L G++C Q N+ E P Q
Sbjct: 4872 ECRVRNL-CQHACRNTEGSYQCLCPAGYRLLPSGKNC-----QDINECEEESIECGPGQM 4925
Query: 303 ----PGSYSCM---CETGYRLAADQHRC 323
GSY C+ C YR C
Sbjct: 4926 CFNTRGSYQCVDTPCPATYRQGPSPGTC 4953
>gi|169177000 PREDICTED: hemicentin 2 [Homo sapiens]
Length = 3783
Score = 104 bits (259), Expect = 3e-22
Identities = 90/330 (27%), Positives = 123/330 (37%), Gaps = 77/330 (23%)
Query: 244 DCSVENGGCEHACNAIPGAPRCQCPAGAALQADGRSCTASATQSCNDLCEHFCVPNP--- 300
+CS C HAC PG C CP G AL D R+C + D H C
Sbjct: 3355 ECSGGPSPCSHACLNAPGRFSCTCPTGFALAWDDRNC-RDVDECAWD--AHLCREGQRCV 3411
Query: 301 DQPGSYSCM--CETGYRLAADQHRCEDVDDCI--LEPSPCPQRCVNTQGGFECHCYPNYD 356
+ GSY C+ C G+R+ AD CEDVD+C+ L+ Q C NT GG C C Y
Sbjct: 3412 NLLGSYRCLPDCGPGFRV-ADGAGCEDVDECLEGLDDCHYNQLCENTPGGHRCSCPRGYR 3470
Query: 357 LVDGECVEPVDPCFRAN--------CEYQCQPLNQTSYLCVCAEG--------------- 393
+ P PC N C YQC L Q SY C+C G
Sbjct: 3471 MQG-----PSLPCLDVNECLQLPKACAYQCHNL-QGSYRCLCPPGQTLLRDGKACTSLER 3524
Query: 394 --------------------FAPIPHEPHRCQMFCNQTACPADCDPNTQASCECPEGYIL 433
+A IP + + + P ++ CP G+I
Sbjct: 3525 NGQNVTTVSHRGPLLPWLRPWASIPGTSYHAWV----SLRPGPMALSSVGRAWCPPGFIR 3580
Query: 434 DDGFICTDIDECENGGFCSGVCHNLPGTFECICGPDSAL------------ARHIGTDCD 481
+G +CTD+DEC C C N G+++C+C L +C
Sbjct: 3581 QNG-VCTDLDECRVRNLCQHACRNTEGSYQCLCPAGYRLLPSGKNCQDINECEEESIECG 3639
Query: 482 SGKVDGGDSGSGEPPPSPTPGSTLTPPAVG 511
G++ GS + +P P + P+ G
Sbjct: 3640 PGQMCFNTRGSYQCVDTPCPATYRQGPSPG 3669
Score = 100 bits (250), Expect = 3e-21
Identities = 72/230 (31%), Positives = 95/230 (41%), Gaps = 49/230 (21%)
Query: 267 CPAGAALQADGRSCTASATQSCNDL-CEHFCVPNPDQPGSYSCMCETGYRLAADQHRCED 325
CP G L + G C S C H C+ + PG +SC C TG+ LA D C D
Sbjct: 3337 CPEGFELDSQGAFCVDRDECSGGPSPCSHACL---NAPGRFSCTCPTGFALAWDDRNCRD 3393
Query: 326 VDDCILEPSPC--PQRCVNTQGGFEC--HCYPNYDLVDGECVEPVDPCFRA--NCEYQCQ 379
VD+C + C QRCVN G + C C P + + DG E VD C +C Y
Sbjct: 3394 VDECAWDAHLCREGQRCVNLLGSYRCLPDCGPGFRVADGAGCEDVDECLEGLDDCHY--- 3450
Query: 380 PLNQTSYLCVCAEGFAPIPHEPHRCQMFCNQTACPADCDPNTQASCECPEGYILDDGFI- 438
+ LC G HR C CP GY + +
Sbjct: 3451 -----NQLCENTPG-------GHR---------------------CSCPRGYRMQGPSLP 3477
Query: 439 CTDIDEC-ENGGFCSGVCHNLPGTFECICGPDSALARHIGTDCDSGKVDG 487
C D++EC + C+ CHNL G++ C+C P L R G C S + +G
Sbjct: 3478 CLDVNECLQLPKACAYQCHNLQGSYRCLCPPGQTLLRD-GKACTSLERNG 3526
Score = 43.1 bits (100), Expect = 7e-04
Identities = 29/88 (32%), Positives = 37/88 (42%), Gaps = 14/88 (15%)
Query: 244 DCSVENGGCEHACNAIPGAPRCQCPAGAALQADGRSCTASATQSCNDLCEHFCVPNPDQ- 302
+C V N C+HAC G+ +C CPAG L G++C Q N+ E P Q
Sbjct: 3590 ECRVRNL-CQHACRNTEGSYQCLCPAGYRLLPSGKNC-----QDINECEEESIECGPGQM 3643
Query: 303 ----PGSYSCM---CETGYRLAADQHRC 323
GSY C+ C YR C
Sbjct: 3644 CFNTRGSYQCVDTPCPATYRQGPSPGTC 3671
>gi|4557733 latent transforming growth factor beta binding protein 2
[Homo sapiens]
Length = 1821
Score = 102 bits (255), Expect = 7e-22
Identities = 83/285 (29%), Positives = 117/285 (41%), Gaps = 37/285 (12%)
Query: 228 PGAVQGHWAREAPGAWDCSVENGGCEHACNAIPGAPRCQ----CPAGAALQADGR-SCTA 282
PG G G++ C + G C+ CP G + + G +C A
Sbjct: 937 PGVCSGGQCTNTEGSYHCECDQGYIMVRKGHCQDINECRHPGTCPDGRCVNSPGSYTCLA 996
Query: 283 ------SATQSCNDL--------CEHFCVPNPDQPGSYSCMCETGYRLAADQHRCEDVDD 328
+ SC D+ C H N + GS+ C CE GY + +D+ C+DVD+
Sbjct: 997 CEEGYRGQSGSCVDVNECLTPGVCAHGKCTNLE--GSFRCSCEQGYEVTSDEKGCQDVDE 1054
Query: 329 CILEPSPCPQRCVNTQGGFECHCYPNYDLV--DGECVEPVDPC-FRANCEYQCQPLNQTS 385
C S C+NT+G F C N V DG E +D C F C S
Sbjct: 1055 CASRASCPTGLCLNTEGSFACSACENGYWVNEDGTACEDLDECAFPGVCPSGVCTNTAGS 1114
Query: 386 YLCV-CAEGFAPIP-----HEPHRCQMFCNQTACPADCDPNTQAS--CECPEGYILDDGF 437
+ C C G+ P P + C+ Q++C NT S C CP+G+ L +G
Sbjct: 1115 FSCKDCDGGYRPSPLGDSCEDVDECE--DPQSSCLGGECKNTVGSYQCLCPQGFQLANGT 1172
Query: 438 ICTDIDECENGGFCS--GVCHNLPGTFECICGPDSALARHIGTDC 480
+C D++EC C+ G C N G+F C+C P A GT C
Sbjct: 1173 VCEDVNECMGEEHCAPHGECLNSHGSFFCLCAPGFVSAEG-GTSC 1216
Score = 97.4 bits (241), Expect = 3e-20
Identities = 65/205 (31%), Positives = 84/205 (40%), Gaps = 34/205 (16%)
Query: 280 CTASATQSCNDLCEHFCVPNPDQPGSYSCMCETGYRLAADQHRCEDVDDCILEPSPCPQR 339
C A AT C CV PD Y C+C GY+L Q C D ++C+ +P R
Sbjct: 848 CAAGATNVCGP---GTCVNLPD---GYRCVCSPGYQLHPSQAYCTDDNECLRDPCKGKGR 901
Query: 340 CVNTQGGFECHCYPNYDLVD----------GECVEPVDPCFRANCEYQCQPLNQTSYLCV 389
C+N G + C CYP Y L EC +P C C + SY C
Sbjct: 902 CINRVGSYSCFCYPGYTLATSGATQECQDINECEQP-GVCSGGQCTN-----TEGSYHCE 955
Query: 390 CAEGFAPIPHEPHRCQMFCNQTACPADC-------DPNTQASCECPEGYILDDGFICTDI 442
C +G+ + CQ N+ P C P + C EGY G C D+
Sbjct: 956 CDQGYIMV--RKGHCQDI-NECRHPGTCPDGRCVNSPGSYTCLACEEGYRGQSG-SCVDV 1011
Query: 443 DECENGGFCS-GVCHNLPGTFECIC 466
+EC G C+ G C NL G+F C C
Sbjct: 1012 NECLTPGVCAHGKCTNLEGSFRCSC 1036
Score = 96.7 bits (239), Expect = 5e-20
Identities = 83/281 (29%), Positives = 113/281 (40%), Gaps = 71/281 (25%)
Query: 256 CNAIPGAPRCQCPAGAALQADGRSC----------------------------------- 280
C +P RC C G L C
Sbjct: 861 CVNLPDGYRCVCSPGYQLHPSQAYCTDDNECLRDPCKGKGRCINRVGSYSCFCYPGYTLA 920
Query: 281 TASATQSCNDL--CEHFCVPNPDQ----PGSYSCMCETGYRLAADQHRCEDVDDCILEPS 334
T+ ATQ C D+ CE V + Q GSY C C+ GY + H C+D+++C P
Sbjct: 921 TSGATQECQDINECEQPGVCSGGQCTNTEGSYHCECDQGYIMVRKGH-CQDINEC-RHPG 978
Query: 335 PCPQ-RCVNTQGGFEC-HCYPNYDLVDGECVEPVDPCFRAN-CEY-QCQPLNQTSYLCVC 390
CP RCVN+ G + C C Y G CV+ V+ C C + +C L + S+ C C
Sbjct: 979 TCPDGRCVNSPGSYTCLACEEGYRGQSGSCVD-VNECLTPGVCAHGKCTNL-EGSFRCSC 1036
Query: 391 AEGFAPIPHEPHRCQ---MFCNQTACPADCDPNTQAS---CECPEGY-ILDDGFICTDID 443
+G+ + + CQ ++ +CP NT+ S C GY + +DG C D+D
Sbjct: 1037 EQGY-EVTSDEKGCQDVDECASRASCPTGLCLNTEGSFACSACENGYWVNEDGTACEDLD 1095
Query: 444 ECENGGFC-SGVCHNLPGTFECICGPDSALARHIGTDCDSG 483
EC G C SGVC N G+F C DCD G
Sbjct: 1096 ECAFPGVCPSGVCTNTAGSFSC-------------KDCDGG 1123
Score = 92.0 bits (227), Expect = 1e-18
Identities = 82/271 (30%), Positives = 122/271 (45%), Gaps = 38/271 (14%)
Query: 256 CNAIPGAPRCQCPAGAALQADGRSCTASATQSCND-LCEHFCVPNPD---QPGSYSCMCE 311
C G+ +C CP G L A+G C + N+ + E C P+ + GS+ C+C
Sbjct: 1151 CKNTVGSYQCLCPQGFQL-ANGTVC-----EDVNECMGEEHCAPHGECLNSHGSFFCLCA 1204
Query: 312 TGYRLAADQHRCEDVDDCILEPSPCPQRCVNTQGGFECHCYPNY--DLVDGECVEPVDPC 369
G+ A C+DVD+C CVNT+G F C C + GECV+ +D C
Sbjct: 1205 PGFVSAEGGTSCQDVDECATTDPCVGGHCVNTEGSFNCLCETGFQPSPESGECVD-IDEC 1263
Query: 370 FRAN---C-EYQCQPLNQTSYLCV--CAEGFAPIPH----EPHRCQMFCNQTACPAD--C 417
C ++C+ + SY CV C GF P+ + C N T C + C
Sbjct: 1264 EDYGDPVCGTWKCEN-SPGSYRCVLGCQPGFHMAPNGDCIDIDEC---ANDTMCGSHGFC 1319
Query: 418 DPNTQAS--CECPEGY-ILDDGFICTDIDECE-NGGFC-SGVCHNLPGTFECICGPDSAL 472
D NT S C C +G+ I G+ C D++ECE C + +C N+ G+F C+C D
Sbjct: 1320 D-NTDGSFRCLCDQGFEISPSGWDCVDVNECELMLAVCGAALCENVEGSFLCLCASDLEE 1378
Query: 473 ARHIGTDC---DSGKVDGGDSGSGEPPPSPT 500
C +G ++ +G+ P+PT
Sbjct: 1379 YDAQEGHCRPRGAGGQSMSEAPTGDHAPAPT 1409
Score = 59.7 bits (143), Expect = 7e-09
Identities = 78/324 (24%), Positives = 108/324 (33%), Gaps = 88/324 (27%)
Query: 224 CTAPPGAVQGHWAREAPGAWDCSVENGGCEHACNAIPGAPRCQCPAGAALQADGRSCTAS 283
C PG V +C+ + C G+ C C G + C
Sbjct: 1201 CLCAPGFVSAEGGTSCQDVDECATTDPCVGGHCVNTEGSFNCLCETGFQPSPESGECV-- 1258
Query: 284 ATQSCNDLCEHFC--VPNPDQPGSYSCM--CETGYRLAADQHRCEDVDDCILEPSPCPQR 339
C D + C + PGSY C+ C+ G+ +A + C D+D+C + C
Sbjct: 1259 DIDECEDYGDPVCGTWKCENSPGSYRCVLGCQPGFHMAPNGD-CIDIDEC-ANDTMCGSH 1316
Query: 340 --CVNTQGGFECHCYPNY-------DLVD-GECVEPVDPCFRANCEYQCQPLNQTSYLCV 389
C NT G F C C + D VD EC + C A CE + S+LC+
Sbjct: 1317 GFCDNTDGSFRCLCDQGFEISPSGWDCVDVNECELMLAVCGAALCENV-----EGSFLCL 1371
Query: 390 CA---------EG-------------------FAPIP-----------HEP--------- 401
CA EG AP P H P
Sbjct: 1372 CASDLEEYDAQEGHCRPRGAGGQSMSEAPTGDHAPAPTRMDCYSGQKGHAPCSSVLGRNT 1431
Query: 402 HRCQMFCNQTA--------CPADCDPNTQASCECPEGYILDDG------FICTDIDECE- 446
+ + C Q A CP++ C +GYI +G + TD DEC
Sbjct: 1432 TQAECCCTQGASWGDACDLCPSEDSAEFSEICPSGKGYIPVEGAWTFGQTMYTDADECVI 1491
Query: 447 -NGGFC-SGVCHNLPGTFECICGP 468
G C +G C N + C+C P
Sbjct: 1492 FGPGLCPNGRCLNTVPGYVCLCNP 1515
Score = 52.4 bits (124), Expect = 1e-06
Identities = 66/290 (22%), Positives = 99/290 (34%), Gaps = 79/290 (27%)
Query: 256 CNAIPGAPRCQ--CPAGAALQADGRSCTASATQSCNDLC-EHFCVPNPDQPGSYSCMCET 312
C PG+ RC C G + +G C + + +C H N D GS+ C+C+
Sbjct: 1276 CENSPGSYRCVLGCQPGFHMAPNG-DCIDIDECANDTMCGSHGFCDNTD--GSFRCLCDQ 1332
Query: 313 GYRLAADQHRCEDVDDCILEPSPCPQR-CVNTQGGFEC--------------HCYPN--- 354
G+ ++ C DV++C L + C C N +G F C HC P
Sbjct: 1333 GFEISPSGWDCVDVNECELMLAVCGAALCENVEGSFLCLCASDLEEYDAQEGHCRPRGAG 1392
Query: 355 ------------------YDLVDGECVEPVDPCF----RANCEYQC-------------- 378
D G+ + PC R + +C
Sbjct: 1393 GQSMSEAPTGDHAPAPTRMDCYSGQ--KGHAPCSSVLGRNTTQAECCCTQGASWGDACDL 1450
Query: 379 ---QPLNQTSYLCVCAEGFAPIPH----------EPHRCQMFCNQTACPADCDPNTQAS- 424
+ + S +C +G+ P+ + C +F CP NT
Sbjct: 1451 CPSEDSAEFSEICPSGKGYIPVEGAWTFGQTMYTDADECVIF-GPGLCPNGRCLNTVPGY 1509
Query: 425 -CECPEGYILDDGFI-CTDIDECENGGFCSGVCHNLPGTFECICGPDSAL 472
C C G+ D C D DEC++ +G C N G+F C C P L
Sbjct: 1510 VCLCNPGFHYDASHKKCEDHDECQDLACENGECVNTEGSFHCFCSPPLTL 1559
Score = 43.5 bits (101), Expect = 5e-04
Identities = 60/241 (24%), Positives = 87/241 (36%), Gaps = 41/241 (17%)
Query: 296 CVPNPDQPGSY-----SCMCETGYRLAADQHRCEDVDDCILEPSPCPQRCVNTQGGFECH 350
C P P +P S C GY+ H C+D+++C+ CVNT+G + C
Sbjct: 589 CAPCPPRPASPVIENGQLECPQGYKRLNLTH-CQDINECLTLGLCKDAECVNTRGSYLCT 647
Query: 351 CYPN--YDLVDGECVEP------VDPCFRANCEYQCQ-PLNQ--TSYLCVCAEGFAPIPH 399
C P D CV C+R+ C PL Q T +C C+
Sbjct: 648 CRPGLMLDPSRSRCVSDKAISMLQGLCYRSLGPGTCTLPLAQRITKQICCCSRVGKAWGS 707
Query: 400 EPHRCQMFCNQTACPADCDPNTQASCE-CP--EGYILDDGFICTDIDECENGGFCSGVCH 456
E +C + P T+A E CP GY I + + E
Sbjct: 708 ECEKCPL------------PGTEAFREICPAGHGYTYASSDIRLSMRKAEEEELARPPRE 755
Query: 457 NLPGTFECICGPDSALARHIGTD--CDSGKV-DGGDSGSGEPPPSPT------PGSTLTP 507
+ + GP + TD ++G + D GDS +G+ S T G+ TP
Sbjct: 756 QGQRSSGALPGPAERQPLRVVTDTWLEAGTIPDKGDSQAGQVTTSVTHAPAWVTGNATTP 815
Query: 508 P 508
P
Sbjct: 816 P 816
Score = 43.1 bits (100), Expect = 7e-04
Identities = 20/54 (37%), Positives = 27/54 (50%), Gaps = 4/54 (7%)
Query: 306 YSCMCETGYRLAADQHRCEDVDDCILEPSPCPQ----RCVNTQGGFECHCYPNY 355
Y+C C G++L A C DV++C P C NT+G + CHC P Y
Sbjct: 1755 YTCDCFEGFQLDAAHMACVDVNECDDLNGPAVLCVHGYCENTEGSYRCHCSPGY 1808
Score = 38.9 bits (89), Expect = 0.013
Identities = 20/51 (39%), Positives = 29/51 (56%), Gaps = 6/51 (11%)
Query: 424 SCECPEGYILDDGFI-CTDIDECE--NGG--FC-SGVCHNLPGTFECICGP 468
+C+C EG+ LD + C D++EC+ NG C G C N G++ C C P
Sbjct: 1756 TCDCFEGFQLDAAHMACVDVNECDDLNGPAVLCVHGYCENTEGSYRCHCSP 1806
Score = 38.1 bits (87), Expect = 0.022
Identities = 32/104 (30%), Positives = 39/104 (37%), Gaps = 18/104 (17%)
Query: 227 PPGAVQGHWAREAPGAWDCSVENGGCEHA-CNAIPGAPRCQCPAGAALQADGRSCTASAT 285
PP +G A E C + NG CE+ C + C C G L A +C
Sbjct: 1725 PPAGFEGLQAEE------CGILNG-CENGRCVRVREGYTCDCFEGFQLDAAHMACVD--V 1775
Query: 286 QSCNDL------CEHFCVPNPDQPGSYSCMCETGYRLAADQHRC 323
C+DL C H N + GSY C C GY A C
Sbjct: 1776 NECDDLNGPAVLCVHGYCENTE--GSYRCHCSPGYVAEAGPPHC 1817
Score = 33.1 bits (74), Expect = 0.71
Identities = 30/102 (29%), Positives = 39/102 (38%), Gaps = 16/102 (15%)
Query: 249 NGGCEHACNAIPGAPRCQCPAGAALQADGRSCTASATQSCNDL-CEHFCVPNPDQPGSYS 307
NG C N +PG C C G A + C C DL CE+ N + GS+
Sbjct: 1499 NGRC---LNTVPGYV-CLCNPGFHYDASHKKCEDH--DECQDLACENGECVNTE--GSFH 1550
Query: 308 CMCETGYRLAADQHRC-------EDVDDCILEPSPCPQRCVN 342
C C L Q RC ED+ D + C ++ N
Sbjct: 1551 CFCSPPLTLDLSQQRCMNSTSSTEDLPDHDIHMDICWKKVTN 1592
Score = 33.1 bits (74), Expect = 0.71
Identities = 34/151 (22%), Positives = 52/151 (34%), Gaps = 32/151 (21%)
Query: 263 PRCQCPAGAALQADGRSCTASATQSCNDLCEHFCVPNPDQPGSYSCMCETGYRLAADQHR 322
P P A AD S Q ++L H+ +P+ P + +
Sbjct: 1687 PEPAFPNTAGHSADRTPILESPLQP-SELQPHYVASHPEPPAGFEGL------------- 1732
Query: 323 CEDVDDCILEPSPCPQRCVNTQGGFECHCYPNYDL-------VD-GECVE---PVDPCFR 371
++C + RCV + G+ C C+ + L VD EC + P C
Sbjct: 1733 --QAEECGILNGCENGRCVRVREGYTCDCFEGFQLDAAHMACVDVNECDDLNGPAVLCVH 1790
Query: 372 ANCEYQCQPLNQTSYLCVCAEGFAPIPHEPH 402
CE + SY C C+ G+ PH
Sbjct: 1791 GYCEN-----TEGSYRCHCSPGYVAEAGPPH 1816
Score = 32.0 bits (71), Expect = 1.6
Identities = 23/66 (34%), Positives = 27/66 (40%), Gaps = 10/66 (15%)
Query: 417 CDPNTQAS------CECPEGYILDDG-FICTDIDECENGGFCSGV--CHNLPGTFECICG 467
C P T + C C GY L CTD +EC C G C N G++ C C
Sbjct: 856 CGPGTCVNLPDGYRCVCSPGYQLHPSQAYCTDDNECLRDP-CKGKGRCINRVGSYSCFCY 914
Query: 468 PDSALA 473
P LA
Sbjct: 915 PGYTLA 920
Database: hs.faa
Posted date: Aug 4, 2009 4:42 PM
Number of letters in database: 18,247,518
Number of sequences in database: 37,866
Lambda K H
0.321 0.138 0.468
Gapped
Lambda K H
0.267 0.0410 0.140
Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Hits to DB: 30,027,608
Number of Sequences: 37866
Number of extensions: 1777329
Number of successful extensions: 10208
Number of sequences better than 10.0: 30
Number of HSP's better than 10.0 without gapping: 137
Number of HSP's successfully gapped in prelim test: 237
Number of HSP's that attempted gapping in prelim test: 6342
Number of HSP's gapped (non-prelim): 1818
length of query: 575
length of database: 18,247,518
effective HSP length: 108
effective length of query: 467
effective length of database: 14,157,990
effective search space: 6611781330
effective search space used: 6611781330
T: 11
A: 40
X1: 16 ( 7.4 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 41 (21.9 bits)
S2: 65 (29.6 bits)
Search results were obtained with NCBI BLAST and RefSeq entries.
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Guide to the Human Genome
Copyright © 2010 by Stewart Scherer. All rights reserved.