BLASTP 2.2.11 [Jun-05-2005] Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer, Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), "Gapped BLAST and PSI-BLAST: a new generation of protein database search programs", Nucleic Acids Res. 25:3389-3402. Query= gi|4507357 transgelin 2 [Homo sapiens] (199 letters) Database: hs.faa 37,866 sequences; 18,247,518 total letters Searching..................................................done Score E Sequences producing significant alignments: (bits) Value gi|4507357 transgelin 2 [Homo sapiens] 409 e-115 gi|56549135 transgelin 3 [Homo sapiens] 301 3e-82 gi|56549139 transgelin 3 [Homo sapiens] 301 3e-82 gi|56549137 transgelin 3 [Homo sapiens] 301 3e-82 gi|48255907 transgelin [Homo sapiens] 273 5e-74 gi|48255905 transgelin [Homo sapiens] 273 5e-74 gi|21361120 calponin 1, basic, smooth muscle [Homo sapiens] 148 3e-36 gi|4502923 calponin 3 [Homo sapiens] 146 1e-35 gi|4758018 calponin 2 isoform a [Homo sapiens] 135 2e-32 gi|41327730 calponin 2 isoform b [Homo sapiens] 114 5e-26 gi|33598968 LIM domain only 7 isoform 1 [Homo sapiens] 44 9e-05 gi|163310745 LIM and calponin homology domains 1 isoform c [Homo... 44 1e-04 gi|163310743 LIM and calponin homology domains 1 isoform b [Homo... 44 1e-04 gi|163310741 LIM and calponin homology domains 1 isoform a [Homo... 44 1e-04 gi|7108367 vav 1 guanine nucleotide exchange factor [Homo sapiens] 42 4e-04 gi|39753961 IQ motif containing GTPase activating protein 3 [Hom... 39 0.004 gi|120432044 vav 3 guanine nucleotide exchange factor isoform 1 ... 38 0.006 gi|197304715 vav 2 guanine nucleotide exchange factor isoform 1 ... 38 0.006 gi|40549448 vav 2 guanine nucleotide exchange factor isoform 2 [... 38 0.006 gi|33859670 leucine-rich repeats and calponin homology (CH) doma... 37 0.008 gi|21281675 growth arrest-specific 2 like 2 [Homo sapiens] 35 0.032 gi|22027525 Rac/Cdc42 guanine nucleotide exchange factor 6 [Homo... 34 0.072 gi|169234649 smoothelin-like 2 isoform 2 [Homo sapiens] 34 0.094 gi|169234647 smoothelin-like 2 isoform 1 [Homo sapiens] 34 0.094 gi|4506787 IQ motif containing GTPase activating protein 1 [Homo... 33 0.21 gi|167614506 L-plastin [Homo sapiens] 32 0.27 gi|22027528 PAK-interacting exchange factor beta isoform b [Homo... 32 0.47 gi|19913394 smoothelin isoform c [Homo sapiens] 31 0.79 gi|117414148 hypothetical protein LOC221322 [Homo sapiens] 30 1.0 gi|19913396 smoothelin isoform b [Homo sapiens] 30 1.4 >gi|4507357 transgelin 2 [Homo sapiens] Length = 199 Score = 409 bits (1052), Expect = e-115 Identities = 199/199 (100%), Positives = 199/199 (100%) Query: 1 MANRGPAYGLSREVQQKIEKQYDADLEQILIQWITTQCRKDVGRPQPGRENFQNWLKDGT 60 MANRGPAYGLSREVQQKIEKQYDADLEQILIQWITTQCRKDVGRPQPGRENFQNWLKDGT Sbjct: 1 MANRGPAYGLSREVQQKIEKQYDADLEQILIQWITTQCRKDVGRPQPGRENFQNWLKDGT 60 Query: 61 VLCELINALYPEGQAPVKKIQASTMAFKQMEQISQFLQAAERYGINTTDIFQTVDLWEGK 120 VLCELINALYPEGQAPVKKIQASTMAFKQMEQISQFLQAAERYGINTTDIFQTVDLWEGK Sbjct: 61 VLCELINALYPEGQAPVKKIQASTMAFKQMEQISQFLQAAERYGINTTDIFQTVDLWEGK 120 Query: 121 NMACVQRTLMNLGGLAVARDDGLFSGDPNWFPKKSKENPRNFSDNQLQEGKNVIGLQMGT 180 NMACVQRTLMNLGGLAVARDDGLFSGDPNWFPKKSKENPRNFSDNQLQEGKNVIGLQMGT Sbjct: 121 NMACVQRTLMNLGGLAVARDDGLFSGDPNWFPKKSKENPRNFSDNQLQEGKNVIGLQMGT 180 Query: 181 NRGASQAGMTGYGMPRQIL 199 NRGASQAGMTGYGMPRQIL Sbjct: 181 NRGASQAGMTGYGMPRQIL 199 >gi|56549135 transgelin 3 [Homo sapiens] Length = 199 Score = 301 bits (770), Expect = 3e-82 Identities = 139/199 (69%), Positives = 169/199 (84%) Query: 1 MANRGPAYGLSREVQQKIEKQYDADLEQILIQWITTQCRKDVGRPQPGRENFQNWLKDGT 60 MANRGP+YGLSREVQ+KIE++YDADLE L+ WI QC +D+ P PGR +FQ WL DGT Sbjct: 1 MANRGPSYGLSREVQEKIEQKYDADLENKLVDWIILQCAEDIEHPPPGRAHFQKWLMDGT 60 Query: 61 VLCELINALYPEGQAPVKKIQASTMAFKQMEQISQFLQAAERYGINTTDIFQTVDLWEGK 120 VLC+LIN+LYP GQ P+ KI S MAFKQMEQISQFL+AAE YG+ TTDIFQTVDLWEGK Sbjct: 61 VLCKLINSLYPPGQEPIPKISESKMAFKQMEQISQFLKAAETYGVRTTDIFQTVDLWEGK 120 Query: 121 NMACVQRTLMNLGGLAVARDDGLFSGDPNWFPKKSKENPRNFSDNQLQEGKNVIGLQMGT 180 +MA VQRTLM LG +AV +DDG + G+P+WF +K+++N R FS+ QL++G+NVIGLQMG+ Sbjct: 121 DMAAVQRTLMALGSVAVTKDDGCYRGEPSWFHRKAQQNRRGFSEEQLRQGQNVIGLQMGS 180 Query: 181 NRGASQAGMTGYGMPRQIL 199 N+GASQAGMTGYGMPRQI+ Sbjct: 181 NKGASQAGMTGYGMPRQIM 199 >gi|56549139 transgelin 3 [Homo sapiens] Length = 199 Score = 301 bits (770), Expect = 3e-82 Identities = 139/199 (69%), Positives = 169/199 (84%) Query: 1 MANRGPAYGLSREVQQKIEKQYDADLEQILIQWITTQCRKDVGRPQPGRENFQNWLKDGT 60 MANRGP+YGLSREVQ+KIE++YDADLE L+ WI QC +D+ P PGR +FQ WL DGT Sbjct: 1 MANRGPSYGLSREVQEKIEQKYDADLENKLVDWIILQCAEDIEHPPPGRAHFQKWLMDGT 60 Query: 61 VLCELINALYPEGQAPVKKIQASTMAFKQMEQISQFLQAAERYGINTTDIFQTVDLWEGK 120 VLC+LIN+LYP GQ P+ KI S MAFKQMEQISQFL+AAE YG+ TTDIFQTVDLWEGK Sbjct: 61 VLCKLINSLYPPGQEPIPKISESKMAFKQMEQISQFLKAAETYGVRTTDIFQTVDLWEGK 120 Query: 121 NMACVQRTLMNLGGLAVARDDGLFSGDPNWFPKKSKENPRNFSDNQLQEGKNVIGLQMGT 180 +MA VQRTLM LG +AV +DDG + G+P+WF +K+++N R FS+ QL++G+NVIGLQMG+ Sbjct: 121 DMAAVQRTLMALGSVAVTKDDGCYRGEPSWFHRKAQQNRRGFSEEQLRQGQNVIGLQMGS 180 Query: 181 NRGASQAGMTGYGMPRQIL 199 N+GASQAGMTGYGMPRQI+ Sbjct: 181 NKGASQAGMTGYGMPRQIM 199 >gi|56549137 transgelin 3 [Homo sapiens] Length = 199 Score = 301 bits (770), Expect = 3e-82 Identities = 139/199 (69%), Positives = 169/199 (84%) Query: 1 MANRGPAYGLSREVQQKIEKQYDADLEQILIQWITTQCRKDVGRPQPGRENFQNWLKDGT 60 MANRGP+YGLSREVQ+KIE++YDADLE L+ WI QC +D+ P PGR +FQ WL DGT Sbjct: 1 MANRGPSYGLSREVQEKIEQKYDADLENKLVDWIILQCAEDIEHPPPGRAHFQKWLMDGT 60 Query: 61 VLCELINALYPEGQAPVKKIQASTMAFKQMEQISQFLQAAERYGINTTDIFQTVDLWEGK 120 VLC+LIN+LYP GQ P+ KI S MAFKQMEQISQFL+AAE YG+ TTDIFQTVDLWEGK Sbjct: 61 VLCKLINSLYPPGQEPIPKISESKMAFKQMEQISQFLKAAETYGVRTTDIFQTVDLWEGK 120 Query: 121 NMACVQRTLMNLGGLAVARDDGLFSGDPNWFPKKSKENPRNFSDNQLQEGKNVIGLQMGT 180 +MA VQRTLM LG +AV +DDG + G+P+WF +K+++N R FS+ QL++G+NVIGLQMG+ Sbjct: 121 DMAAVQRTLMALGSVAVTKDDGCYRGEPSWFHRKAQQNRRGFSEEQLRQGQNVIGLQMGS 180 Query: 181 NRGASQAGMTGYGMPRQIL 199 N+GASQAGMTGYGMPRQI+ Sbjct: 181 NKGASQAGMTGYGMPRQIM 199 >gi|48255907 transgelin [Homo sapiens] Length = 201 Score = 273 bits (699), Expect = 5e-74 Identities = 130/200 (65%), Positives = 165/200 (82%), Gaps = 1/200 (0%) Query: 1 MANRGPAYGLSREVQQKIEKQYDADLEQILIQWITTQCRKDVGRPQPGRENFQNWLKDGT 60 MAN+GP+YG+SREVQ KIEK+YD +LE+ L++WI QC DVGRP GR FQ WLK+G Sbjct: 1 MANKGPSYGMSREVQSKIEKKYDEELEERLVEWIIVQCGPDVGRPDRGRLGFQVWLKNGV 60 Query: 61 VLCELINALYPEGQAPVKKIQ-ASTMAFKQMEQISQFLQAAERYGINTTDIFQTVDLWEG 119 +L +L+N+LYP+G PVK + +M FKQMEQ++QFL+AAE YG+ TD+FQTVDL+EG Sbjct: 61 ILSKLVNSLYPDGSKPVKVPENPPSMVFKQMEQVAQFLKAAEDYGVIKTDMFQTVDLFEG 120 Query: 120 KNMACVQRTLMNLGGLAVARDDGLFSGDPNWFPKKSKENPRNFSDNQLQEGKNVIGLQMG 179 K+MA VQRTLM LG LAV ++DG + GDPNWF KK++E+ R F+++QLQEGK+VIGLQMG Sbjct: 121 KDMAAVQRTLMALGSLAVTKNDGHYRGDPNWFMKKAQEHKREFTESQLQEGKHVIGLQMG 180 Query: 180 TNRGASQAGMTGYGMPRQIL 199 +NRGASQAGMTGYG PRQI+ Sbjct: 181 SNRGASQAGMTGYGRPRQII 200 >gi|48255905 transgelin [Homo sapiens] Length = 201 Score = 273 bits (699), Expect = 5e-74 Identities = 130/200 (65%), Positives = 165/200 (82%), Gaps = 1/200 (0%) Query: 1 MANRGPAYGLSREVQQKIEKQYDADLEQILIQWITTQCRKDVGRPQPGRENFQNWLKDGT 60 MAN+GP+YG+SREVQ KIEK+YD +LE+ L++WI QC DVGRP GR FQ WLK+G Sbjct: 1 MANKGPSYGMSREVQSKIEKKYDEELEERLVEWIIVQCGPDVGRPDRGRLGFQVWLKNGV 60 Query: 61 VLCELINALYPEGQAPVKKIQ-ASTMAFKQMEQISQFLQAAERYGINTTDIFQTVDLWEG 119 +L +L+N+LYP+G PVK + +M FKQMEQ++QFL+AAE YG+ TD+FQTVDL+EG Sbjct: 61 ILSKLVNSLYPDGSKPVKVPENPPSMVFKQMEQVAQFLKAAEDYGVIKTDMFQTVDLFEG 120 Query: 120 KNMACVQRTLMNLGGLAVARDDGLFSGDPNWFPKKSKENPRNFSDNQLQEGKNVIGLQMG 179 K+MA VQRTLM LG LAV ++DG + GDPNWF KK++E+ R F+++QLQEGK+VIGLQMG Sbjct: 121 KDMAAVQRTLMALGSLAVTKNDGHYRGDPNWFMKKAQEHKREFTESQLQEGKHVIGLQMG 180 Query: 180 TNRGASQAGMTGYGMPRQIL 199 +NRGASQAGMTGYG PRQI+ Sbjct: 181 SNRGASQAGMTGYGRPRQII 200 >gi|21361120 calponin 1, basic, smooth muscle [Homo sapiens] Length = 297 Score = 148 bits (374), Expect = 3e-36 Identities = 84/196 (42%), Positives = 115/196 (58%), Gaps = 14/196 (7%) Query: 3 NRGPAYGLSREVQQKIEKQYDADLEQILIQWITTQCRKDVGRPQPGRENFQNWLKDGTVL 62 NRGPAYGLS EV+ K+ ++YD EQ L +WI + +G NF + LKDG +L Sbjct: 7 NRGPAYGLSAEVKNKLAQKYDHQREQELREWIEGVTGRRIGN------NFMDGLKDGIIL 60 Query: 63 CELINALYPEGQAPVKKIQASTMAFKQMEQISQFLQAAERYGINTTDIFQTVDLWEGKNM 122 CE IN L P VKKI ST + Q+E I F++A +YG+ DIF+ DL+E N Sbjct: 61 CEFINKLQP---GSVKKINESTQNWHQLENIGNFIKAITKYGVKPHDIFEANDLFENTNH 117 Query: 123 ACVQRTLMNLGGLAVARDDGLFSGDPNWFPKKSKENPRNFSDNQLQEGKNVIGLQMGTNR 182 VQ TL+ L +A + + + G K +++ R F +L+EG+N+IGLQMGTN+ Sbjct: 118 TQVQSTLLALASMAKTKGNKVNVG-----VKYAEKQERKFEPGKLREGRNIIGLQMGTNK 172 Query: 183 GASQAGMTGYGMPRQI 198 ASQ GMT YG R + Sbjct: 173 FASQQGMTAYGTRRHL 188 >gi|4502923 calponin 3 [Homo sapiens] Length = 329 Score = 146 bits (369), Expect = 1e-35 Identities = 85/196 (43%), Positives = 116/196 (59%), Gaps = 12/196 (6%) Query: 3 NRGPAYGLSREVQQKIEKQYDADLEQILIQWITTQCRKDVGRPQPGRENFQNWLKDGTVL 62 N+GP+YGLS EV+ KI +YD E+ L WI +G NFQ LKDG +L Sbjct: 5 NKGPSYGLSAEVKNKIASKYDHQAEEDLRNWIEEVTGMSIG------PNFQLGLKDGIIL 58 Query: 63 CELINALYPEGQAPVKKIQASTMAFKQMEQISQFLQAAERYGINTTDIFQTVDLWEGKNM 122 CELIN L P VKK+ S++ + Q+E I F++A + YG+ DIF+ DL+E NM Sbjct: 59 CELINKLQP---GSVKKVNESSLNWPQLENIGNFIKAIQAYGMKPHDIFEANDLFENGNM 115 Query: 123 ACVQRTLMNLGGLAVARDDGLFSGDPNWFPKKSKENPRNFSDNQLQEGKNVIGLQMGTNR 182 VQ TL+ L GLA + F + K +++ R F + +L+ G++VIGLQMGTN+ Sbjct: 116 TQVQTTLVALAGLAKTKG---FHTTIDIGVKYAEKQTRRFDEGKLKAGQSVIGLQMGTNK 172 Query: 183 GASQAGMTGYGMPRQI 198 ASQAGMT YG R + Sbjct: 173 CASQAGMTAYGTRRHL 188 >gi|4758018 calponin 2 isoform a [Homo sapiens] Length = 309 Score = 135 bits (341), Expect = 2e-32 Identities = 83/196 (42%), Positives = 114/196 (58%), Gaps = 12/196 (6%) Query: 3 NRGPAYGLSREVQQKIEKQYDADLEQILIQWITTQCRKDVGRPQPGRENFQNWLKDGTVL 62 N+GP+YGLS EV+ ++ +YD E L WI +G +FQ LKDGT+L Sbjct: 7 NKGPSYGLSAEVKNRLLSKYDPQKEAELRTWIEGLTGLSIG------PDFQKGLKDGTIL 60 Query: 63 CELINALYPEGQAPVKKIQASTMAFKQMEQISQFLQAAERYGINTTDIFQTVDLWEGKNM 122 C L+N L P V KI S + Q+E +S F++A YG+N D+F+ DL+E NM Sbjct: 61 CTLMNKLQP---GSVPKINRSMQNWHQLENLSNFIKAMVSYGMNPVDLFEANDLFESGNM 117 Query: 123 ACVQRTLMNLGGLAVARDDGLFSGDPNWFPKKSKENPRNFSDNQLQEGKNVIGLQMGTNR 182 VQ +L+ L G A + GL SG + K S++ RNF D ++ G+ VIGLQMGTN+ Sbjct: 118 TQVQVSLLALAGKAKTK--GLQSG-VDIGVKYSEKQERNFDDATMKAGQCVIGLQMGTNK 174 Query: 183 GASQAGMTGYGMPRQI 198 ASQ+GMT YG R + Sbjct: 175 CASQSGMTAYGTRRHL 190 >gi|41327730 calponin 2 isoform b [Homo sapiens] Length = 270 Score = 114 bits (285), Expect = 5e-26 Identities = 73/196 (37%), Positives = 102/196 (52%), Gaps = 11/196 (5%) Query: 3 NRGPAYGLSREVQQKIEKQYDADLEQILIQWITTQCRKDVGRPQPGRENFQNWLKDGTVL 62 N+GP+YGLS EV+ ++ +YD E L WI +G +FQ LKDGT+L Sbjct: 7 NKGPSYGLSAEVKNRLLSKYDPQKEAELRTWIEGLTGLSIG------PDFQKGLKDGTIL 60 Query: 63 CELINALYPEGQAPVKKIQASTMAFKQMEQISQFLQAAERYGINTTDIFQTVDLWEGKNM 122 C L+N L P V KI S + Q+E +S F++A YG+N D+F+ DL+E NM Sbjct: 61 CTLMNKLQP---GSVPKINRSMQNWHQLENLSNFIKAMVSYGMNPVDLFEANDLFESGNM 117 Query: 123 ACVQRTLMNLGGLAVARDDGLFSGDPNWFPKKSKENPRNFSDNQLQEGKNVIGLQMGTNR 182 VQ +L+ L G SG + ++ +P+N + + I LQMGTN+ Sbjct: 118 TQVQVSLLALAGKMGTNKCASQSGMTAYGTRRHLYDPKNHILPPMDH--STISLQMGTNK 175 Query: 183 GASQAGMTGYGMPRQI 198 ASQ GMT G R I Sbjct: 176 CASQVGMTAPGTRRHI 191 >gi|33598968 LIM domain only 7 isoform 1 [Homo sapiens] Length = 1349 Score = 43.9 bits (102), Expect = 9e-05 Identities = 24/78 (30%), Positives = 43/78 (55%), Gaps = 3/78 (3%) Query: 50 ENFQNWLKDGTVLCELINALYPEGQAPVKKIQASTMAFKQMEQISQFLQAAERYGINTTD 109 ++F+ L++G +LC+LIN L P +KKI + ++ I+ FL+A E+ G+ Sbjct: 85 KDFRASLENGVLLCDLINKLKP---GVIKKINRLSTPIAGLDNINVFLKACEQIGLKEAQ 141 Query: 110 IFQTVDLWEGKNMACVQR 127 +F DL + N V++ Sbjct: 142 LFHPGDLQDLSNRVTVKQ 159 >gi|163310745 LIM and calponin homology domains 1 isoform c [Homo sapiens] Length = 1056 Score = 43.5 bits (101), Expect = 1e-04 Identities = 24/79 (30%), Positives = 41/79 (51%), Gaps = 3/79 (3%) Query: 48 GRENFQNWLKDGTVLCELINALYPEGQAPVKKIQASTMAFKQMEQISQFLQAAERYGINT 107 G ++F+ L++G +LCEL+NA+ P VKKI ++ I FL+ + G+ Sbjct: 40 GDKDFRTGLENGILLCELLNAIKP---GLVKKINRLPTPIAGLDNIILFLRGCKELGLKE 96 Query: 108 TDIFQTVDLWEGKNMACVQ 126 + +F DL + N V+ Sbjct: 97 SQLFDPSDLQDTSNRVTVK 115 >gi|163310743 LIM and calponin homology domains 1 isoform b [Homo sapiens] Length = 1057 Score = 43.5 bits (101), Expect = 1e-04 Identities = 24/79 (30%), Positives = 41/79 (51%), Gaps = 3/79 (3%) Query: 48 GRENFQNWLKDGTVLCELINALYPEGQAPVKKIQASTMAFKQMEQISQFLQAAERYGINT 107 G ++F+ L++G +LCEL+NA+ P VKKI ++ I FL+ + G+ Sbjct: 40 GDKDFRTGLENGILLCELLNAIKP---GLVKKINRLPTPIAGLDNIILFLRGCKELGLKE 96 Query: 108 TDIFQTVDLWEGKNMACVQ 126 + +F DL + N V+ Sbjct: 97 SQLFDPSDLQDTSNRVTVK 115 >gi|163310741 LIM and calponin homology domains 1 isoform a [Homo sapiens] Length = 1083 Score = 43.5 bits (101), Expect = 1e-04 Identities = 24/79 (30%), Positives = 41/79 (51%), Gaps = 3/79 (3%) Query: 48 GRENFQNWLKDGTVLCELINALYPEGQAPVKKIQASTMAFKQMEQISQFLQAAERYGINT 107 G ++F+ L++G +LCEL+NA+ P VKKI ++ I FL+ + G+ Sbjct: 40 GDKDFRTGLENGILLCELLNAIKP---GLVKKINRLPTPIAGLDNIILFLRGCKELGLKE 96 Query: 108 TDIFQTVDLWEGKNMACVQ 126 + +F DL + N V+ Sbjct: 97 SQLFDPSDLQDTSNRVTVK 115 >gi|7108367 vav 1 guanine nucleotide exchange factor [Homo sapiens] Length = 845 Score = 41.6 bits (96), Expect = 4e-04 Identities = 24/90 (26%), Positives = 47/90 (52%), Gaps = 2/90 (2%) Query: 56 LKDGTVLCELINALYPEG-QAPVKKIQASTMAFKQMEQISQFLQAA-ERYGINTTDIFQT 113 L+DG +LC+L+N L P ++ F ++ I FL E++G+ +++F+ Sbjct: 37 LRDGVLLCQLLNNLLPHAINLREVNLRPQMSQFLCLKNIRTFLSTCCEKFGLKRSELFEA 96 Query: 114 VDLWEGKNMACVQRTLMNLGGLAVARDDGL 143 DL++ ++ V TL L +A++ G+ Sbjct: 97 FDLFDVQDFGKVIYTLSALSWTPIAQNRGI 126 >gi|39753961 IQ motif containing GTPase activating protein 3 [Homo sapiens] Length = 1631 Score = 38.5 bits (88), Expect = 0.004 Identities = 30/121 (24%), Positives = 59/121 (48%), Gaps = 14/121 (11%) Query: 10 LSREVQQKIEKQYDADLEQILIQWITTQCRKDVGRPQPGRENFQNWLKDGTVLCELINAL 69 + + +Q + QY LE+ +W+ ++++ P E+ +N G +L +L + Sbjct: 21 MDEQRRQNVAYQYLCRLEEAK-RWMEACLKEELPSPVELEESLRN----GVLLAKLGHCF 75 Query: 70 YPEGQAPVKKI--------QASTMAFKQMEQISQFLQAAERYGINTTDIFQTVDLWEGKN 121 P P+KKI QA+ + F+ + I+ +L A G+ +T +T D+++ KN Sbjct: 76 APS-VVPLKKIYDVEQLRYQATGLHFRHTDNINFWLSAIAHIGLPSTFFPETTDIYDKKN 134 Query: 122 M 122 M Sbjct: 135 M 135 >gi|120432044 vav 3 guanine nucleotide exchange factor isoform 1 [Homo sapiens] Length = 847 Score = 37.7 bits (86), Expect = 0.006 Identities = 24/90 (26%), Positives = 44/90 (48%), Gaps = 2/90 (2%) Query: 56 LKDGTVLCELINALYPEG-QAPVKKIQASTMAFKQMEQISQFLQA-AERYGINTTDIFQT 113 L+DG +LC+L+N L ++ F ++ I FL A E +G+ +++F+ Sbjct: 37 LRDGVLLCQLLNNLRAHSINLKEINLRPQMSQFLCLKNIRTFLTACCETFGMRKSELFEA 96 Query: 114 VDLWEGKNMACVQRTLMNLGGLAVARDDGL 143 DL++ ++ V TL L +A G+ Sbjct: 97 FDLFDVRDFGKVIETLSRLSRTPIALATGI 126 >gi|197304715 vav 2 guanine nucleotide exchange factor isoform 1 [Homo sapiens] Length = 878 Score = 37.7 bits (86), Expect = 0.006 Identities = 23/91 (25%), Positives = 50/91 (54%), Gaps = 4/91 (4%) Query: 56 LKDGTVLCELINALYPEGQAPVKKI--QASTMAFKQMEQISQFLQAA-ERYGINTTDIFQ 112 L+DG +LC+L++ L P G +K I + F ++ I FL+ +++G+ +++F Sbjct: 37 LRDGVLLCQLLHNLSP-GSIDLKDINFRPQMSQFLCLKNIRTFLKVCHDKFGLRNSELFD 95 Query: 113 TVDLWEGKNMACVQRTLMNLGGLAVARDDGL 143 DL++ ++ V + L ++A++ G+ Sbjct: 96 PFDLFDVRDFGKVISAVSRLSLHSIAQNKGI 126 >gi|40549448 vav 2 guanine nucleotide exchange factor isoform 2 [Homo sapiens] Length = 839 Score = 37.7 bits (86), Expect = 0.006 Identities = 23/91 (25%), Positives = 50/91 (54%), Gaps = 4/91 (4%) Query: 56 LKDGTVLCELINALYPEGQAPVKKI--QASTMAFKQMEQISQFLQAA-ERYGINTTDIFQ 112 L+DG +LC+L++ L P G +K I + F ++ I FL+ +++G+ +++F Sbjct: 37 LRDGVLLCQLLHNLSP-GSIDLKDINFRPQMSQFLCLKNIRTFLKVCHDKFGLRNSELFD 95 Query: 113 TVDLWEGKNMACVQRTLMNLGGLAVARDDGL 143 DL++ ++ V + L ++A++ G+ Sbjct: 96 PFDLFDVRDFGKVISAVSRLSLHSIAQNKGI 126 >gi|33859670 leucine-rich repeats and calponin homology (CH) domain containing 1 [Homo sapiens] Length = 728 Score = 37.4 bits (85), Expect = 0.008 Identities = 36/149 (24%), Positives = 63/149 (42%), Gaps = 18/149 (12%) Query: 6 PAYGLSREVQQ-KIEKQYDADLEQILIQWITTQCRKDVGRPQPGRENFQNWLKDGTVLCE 64 P + + R+++Q + EK+ L + + + +D+G L DG VLC Sbjct: 565 PQFTIRRKMEQMREEKELVEQLRESIEMRLKVSLHEDLGAA----------LMDGVVLCH 614 Query: 65 LINALYPEGQA----PVKKIQASTMAFKQMEQISQFLQAAERYGINTTDIFQTVDL--WE 118 L+N + P A P + +MA K + FL+A + G+ D+ D+ + Sbjct: 615 LVNHIRPRSVASIHVPSPAVPKLSMA-KCRRNVENFLEACRKLGVPEADLCSPCDILQLD 673 Query: 119 GKNMACVQRTLMNLGGLAVARDDGLFSGD 147 +++ TL+ LG A L S D Sbjct: 674 FRHIRKTVDTLLALGEKAPPPTSALRSRD 702 >gi|21281675 growth arrest-specific 2 like 2 [Homo sapiens] Length = 880 Score = 35.4 bits (80), Expect = 0.032 Identities = 36/136 (26%), Positives = 55/136 (40%), Gaps = 24/136 (17%) Query: 17 KIEKQYDADLEQILIQWITTQCRKDVGRPQPGRENFQNWLKDGTVLCELIN-------AL 69 K +QY +++ L +W+ D+ NF L+ G VLC+ N A Sbjct: 25 KSSEQYLEAMKEDLAEWLRDLYGLDIDAA-----NFLQVLETGLVLCQHANVVTDAALAF 79 Query: 70 YPEGQAPVKKIQ-----------ASTMAFKQMEQISQFLQ-AAERYGINTTDIFQTVDLW 117 E A +KI A F+ + +S F+Q + GI +F+T DL Sbjct: 80 LAEAPAQAQKIPMPRVGVSCNGAAQPGTFQARDNVSNFIQWCRKEMGIQEVLMFETEDLV 139 Query: 118 EGKNMACVQRTLMNLG 133 KN+ V L+ LG Sbjct: 140 LRKNVKNVVLCLLELG 155 >gi|22027525 Rac/Cdc42 guanine nucleotide exchange factor 6 [Homo sapiens] Length = 776 Score = 34.3 bits (77), Expect = 0.072 Identities = 31/109 (28%), Positives = 52/109 (47%), Gaps = 13/109 (11%) Query: 27 EQILIQWITT-----QCRKDVGRPQPGRENFQNWLKDGTVLCELINALYPEGQAPVKKIQ 81 E+ ++ W+ + +K + P+ E ++ LK+G VLC+LIN L P G + Sbjct: 4 EEQIVTWLISLGVLESPKKTICDPE---EFLKSSLKNGVVLCKLINRLMP-GSVEKFCLD 59 Query: 82 ASTMAFKQMEQISQFLQAAERYGINTTDIFQTVDLWEGKNMACVQRTLM 130 T A + I+ FL+ + +IF DL+ G N + V TL+ Sbjct: 60 PQTEA-DCINNINDFLKGCATLQV---EIFDPDDLYSGVNFSKVLSTLL 104 >gi|169234649 smoothelin-like 2 isoform 2 [Homo sapiens] Length = 317 Score = 33.9 bits (76), Expect = 0.094 Identities = 19/77 (24%), Positives = 39/77 (50%), Gaps = 10/77 (12%) Query: 24 ADLEQILIQWITTQCR-KDVGRPQPGRENFQNWLKDGTVLCELINALYPE-----GQAPV 77 + ++QIL++W CR K +G +NF + DG C L+++ +P+ +P Sbjct: 207 SSIKQILLEW----CRSKTLGYQHVDLQNFSSSWSDGMAFCALVHSFFPDAFDYNSLSPT 262 Query: 78 KKIQASTMAFKQMEQIS 94 ++ + +AF E ++ Sbjct: 263 QRQKNFELAFTMAENLA 279 >gi|169234647 smoothelin-like 2 isoform 1 [Homo sapiens] Length = 461 Score = 33.9 bits (76), Expect = 0.094 Identities = 19/77 (24%), Positives = 39/77 (50%), Gaps = 10/77 (12%) Query: 24 ADLEQILIQWITTQCR-KDVGRPQPGRENFQNWLKDGTVLCELINALYPE-----GQAPV 77 + ++QIL++W CR K +G +NF + DG C L+++ +P+ +P Sbjct: 351 SSIKQILLEW----CRSKTLGYQHVDLQNFSSSWSDGMAFCALVHSFFPDAFDYNSLSPT 406 Query: 78 KKIQASTMAFKQMEQIS 94 ++ + +AF E ++ Sbjct: 407 QRQKNFELAFTMAENLA 423 >gi|4506787 IQ motif containing GTPase activating protein 1 [Homo sapiens] Length = 1657 Score = 32.7 bits (73), Expect = 0.21 Identities = 27/116 (23%), Positives = 54/116 (46%), Gaps = 14/116 (12%) Query: 15 QQKIEKQYDADLEQILIQWITTQCRKDVGRPQPGRENFQNWLKDGTVLCELINALYPEGQ 74 +Q + +Y LE+ +W+ +D+ P + L++G L +L N P+ Sbjct: 36 RQNVAYEYLCHLEEAK-RWMEACLGEDL----PPTTELEEGLRNGVYLAKLGNFFSPK-V 89 Query: 75 APVKKI--------QASTMAFKQMEQISQFLQAAERYGINTTDIFQTVDLWEGKNM 122 +KKI +A+ + F+ + + Q+L A + G+ +T D+++ KNM Sbjct: 90 VSLKKIYDREQTRYKATGLHFRHTDNVIQWLNAMDEIGLPKIFYPETTDIYDRKNM 145 >gi|167614506 L-plastin [Homo sapiens] Length = 627 Score = 32.3 bits (72), Expect = 0.27 Identities = 28/117 (23%), Positives = 44/117 (37%), Gaps = 6/117 (5%) Query: 9 GLSREVQQKIEKQYDADLEQILIQWITTQCRKD-----VGRPQPGRENFQNWLKDGTVLC 63 G S + + Y + + + WI D V P + N + DG VLC Sbjct: 105 GTSEQSSVGTQHSYSEEEKYAFVNWINKALENDPDCRHVIPMNPNTNDLFNAVGDGIVLC 164 Query: 64 ELINALYPEGQAPVKKIQASTMAFKQMEQISQFLQAAERYGINTTDIFQTVDLWEGK 120 ++IN P+ + F E ++ L +A G + +I DL EGK Sbjct: 165 KMINLSVPDTIDERTINKKKLTPFTIQENLNLALNSASAIGCHVVNI-GAEDLKEGK 220 >gi|22027528 PAK-interacting exchange factor beta isoform b [Homo sapiens] Length = 782 Score = 31.6 bits (70), Expect = 0.47 Identities = 27/91 (29%), Positives = 42/91 (46%), Gaps = 8/91 (8%) Query: 56 LKDGTVLCELINALYPEGQAPVKKIQASTMAFKQ-MEQISQFLQAAERYGINTTDIFQTV 114 LKDG VLC L+ L P ++K+ + + + I +FL+ + F Sbjct: 35 LKDGVVLCRLLERLLP---GTIEKVYPEPRSESECLSNIREFLRGCG--ASLRLETFDAN 89 Query: 115 DLWEGKNMACVQRTLMNLGGLAVARDDGLFS 145 DL++G+N V +L+ L V D GL S Sbjct: 90 DLYQGQNFNKVLSSLVTLN--KVTADIGLGS 118 >gi|19913394 smoothelin isoform c [Homo sapiens] Length = 917 Score = 30.8 bits (68), Expect = 0.79 Identities = 20/73 (27%), Positives = 34/73 (46%), Gaps = 8/73 (10%) Query: 26 LEQILIQWITTQCRKDVGRPQPGRENFQNWLKDGTVLCELINALYPE----GQ-APVKKI 80 ++Q+L+ W + R G +NF + DG C L++ +PE GQ +P + Sbjct: 801 IKQMLLDWCRAKTR---GYEHVDIQNFSSSWSDGMAFCALVHNFFPEAFDYGQLSPQNRR 857 Query: 81 QASTMAFKQMEQI 93 Q +AF E + Sbjct: 858 QNFEVAFSSAEML 870 >gi|117414148 hypothetical protein LOC221322 [Homo sapiens] Length = 1257 Score = 30.4 bits (67), Expect = 1.0 Identities = 29/113 (25%), Positives = 47/113 (41%), Gaps = 23/113 (20%) Query: 28 QILIQWITTQCRKDVGRPQPGRENFQNWLKDGTVLCELINA---LYPEGQ-----APVKK 79 QI +QWIT QC F N+L D +C I L P+ Q A K Sbjct: 1155 QICLQWIT-QC-------------FWNYL-DWIEICHYIATCVFLGPDYQVYICIAVFKH 1199 Query: 80 IQASTMAFKQMEQISQFLQAAERYGINTTDIFQTVDLWEGKNMACVQRTLMNL 132 +Q + Q + + FL+ +G +D F+ +++ E + R + N+ Sbjct: 1200 LQQDILQHTQTQDLQVFLKEEALHGFRVSDYFEYMEILEQNYRTVLLRDMRNI 1252 >gi|19913396 smoothelin isoform b [Homo sapiens] Length = 915 Score = 30.0 bits (66), Expect = 1.4 Identities = 20/71 (28%), Positives = 33/71 (46%), Gaps = 8/71 (11%) Query: 26 LEQILIQWITTQCRKDVGRPQPGRENFQNWLKDGTVLCELINALYPE----GQ-APVKKI 80 ++Q+L+ W + R G +NF + DG C L++ +PE GQ +P + Sbjct: 801 IKQMLLDWCRAKTR---GYEHVDIQNFSSSWSDGMAFCALVHNFFPEAFDYGQLSPQNRR 857 Query: 81 QASTMAFKQME 91 Q +AF E Sbjct: 858 QNFEVAFSSAE 868 Database: hs.faa Posted date: Aug 4, 2009 4:42 PM Number of letters in database: 18,247,518 Number of sequences in database: 37,866 Lambda K H 0.317 0.134 0.402 Gapped Lambda K H 0.267 0.0410 0.140 Matrix: BLOSUM62 Gap Penalties: Existence: 11, Extension: 1 Number of Hits to DB: 7,662,885 Number of Sequences: 37866 Number of extensions: 320227 Number of successful extensions: 771 Number of sequences better than 10.0: 30 Number of HSP's better than 10.0 without gapping: 15 Number of HSP's successfully gapped in prelim test: 30 Number of HSP's that attempted gapping in prelim test: 722 Number of HSP's gapped (non-prelim): 56 length of query: 199 length of database: 18,247,518 effective HSP length: 97 effective length of query: 102 effective length of database: 14,574,516 effective search space: 1486600632 effective search space used: 1486600632 T: 11 A: 40 X1: 16 ( 7.3 bits) X2: 38 (14.6 bits) X3: 64 (24.7 bits) S1: 41 (21.7 bits) S2: 59 (27.3 bits)
Search results were obtained with NCBI BLAST and RefSeq entries.
Guide to the Human Genome
Copyright © 2010 by Stewart Scherer. All rights reserved.