Guide to the Human Genome
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Name: IQGAP1 Sequence: fasta or formatted (1657aa) NCBI GI: 4506787
Description:

IQ motif containing GTPase activating protein 1

Referenced in:

Additional Interaction Domain Families

Composition:

amino acid map
 Amino acid        Percentage    Count  Longest homopolymer
 A alanine             8.1        134           2
 C cysteine            0.7         11           1
 D aspartate           6.0        100           2
 E glutamate           8.1        135           3
 F phenylalanine       2.8         47           2
 G glycine             4.4         73           2
 H histidine           1.9         32           1
 I isoleucine          6.2        102           2
 K lysine              8.1        134           4
 L leucine            11.2        185           3
 M methionine          2.4         40           3
 N asparagine          5.4         90           2
 P proline             3.1         51           2
 Q glutamine           6.7        111           3
 R arginine            5.0         83           3
 S serine              5.1         84           3
 T threonine           4.6         77           2
 V valine              5.6         93           3
 W tryptophan          0.8         13           1
 Y tyrosine            3.7         62           4
Comparative genomics:

Search single species RefSeq proteins at NCBI
   H. sapiens
   M. musculus
   D. rerio
   C. intestinalis
   S. purpuratus
   D. melanogaster
   C. elegans
   A. thaliana
   S. cerevisiae
   E. coli W3110
   A. pernix K1

Search summary

comparative genomics plot

   Figure data

Additional searches of
RefSeq proteins at NCBI

   All
   Eukaryotes
   Bacteria
   Archaea
   Viruses
   Primates
   Mammals
   Vertebrates

Related human proteins:
Protein          Relative score         Description

Self-match            1.000   IQ motif containing GTPase activating protein 1 [Homo... 
IQGAP3                0.585   IQ motif containing GTPase activating protein 3 [Hom...
IQGAP2                0.454   IQ motif containing GTPase activating protein 2 [Ho...
NF1                   0.015   neurofibromin isoform 2 
NF1                   0.013   neurofibromin isoform 1 
RASAL1                0.011   RAS protein activator like 1 
MYO18A                0.008   myosin 18A isoform b 
MYO18A                0.008   myosin 18A isoform a 
GOLGA4                0.008   golgi autoantigen, golgin subfamily a, 4 
MYH2                  0.008   myosin, heavy chain 2, skeletal muscle, adult [Homo...
MYH2                  0.008   myosin, heavy chain 2, skeletal muscle, adult [Homo...
MYH10                 0.007   myosin, heavy polypeptide 10, non-muscle 
RASA1                 0.007   RAS p21 protein activator 1 isoform 1 
RASA1                 0.007   RAS p21 protein activator 1 isoform 2 
GAPVD1                0.007   GTPase activating protein and VPS9 domains 1 
MYH4                  0.007   myosin, heavy polypeptide 4, skeletal muscle 
LOC100132214          0.007   PREDICTED: similar to calcium-promoted Ras inactiva...
LOC100132214          0.007   PREDICTED: similar to calcium-promoted Ras inactiva...
LOC100132214          0.007   PREDICTED: similar to calcium-promoted Ras inactiva...
LOC100132214          0.007   PREDICTED: similar to calcium-promoted Ras inactiva...
MYH15                 0.006   myosin, heavy polypeptide 15 
RASA4                 0.006   RAS p21 protein activator 4 isoform 2 
RASA4                 0.006   RAS p21 protein activator 4 isoform 1 
ASPM                  0.006   asp (abnormal spindle)-like, microcephaly associate...
SYNGAP1               0.006   synaptic Ras GTPase activating protein 1 
MYH1                  0.006   myosin, heavy chain 1, skeletal muscle, adult [Homo...
MYH6                  0.006   myosin heavy chain 6 
MYH8                  0.006   myosin, heavy chain 8, skeletal muscle, perinatal [...
RASAL2                0.006   RAS protein activator like 2 isoform 1 
MYO9A                 0.006   myosin IXA 
Human BLASTP results (used to prepare the table)

Gene descriptions are from NCBI RefSeq. Search results were obtained with NCBI BLAST and RefSeq entries. When identical proteins are present, the self-match may not be listed first in BLASTP output. In such cases, the table above has been reordered to place it first.

See About the Figures for the scoring system used in the figure above right. The same scoring system was used in the table of BLASTP results.


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Guide to the Human Genome
Copyright © 2010 by Stewart Scherer. All rights reserved.

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