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Search of human proteins with 4507353
BLASTP 2.2.11 [Jun-05-2005]
Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer,
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997),
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs", Nucleic Acids Res. 25:3389-3402.
Query= gi|4507353 TBP-associated factor 15 isoform 2 [Homo sapiens]
(589 letters)
Database: hs.faa
37,866 sequences; 18,247,518 total letters
Searching..................................................done
Score E
Sequences producing significant alignments: (bits) Value
gi|4507353 TBP-associated factor 15 isoform 2 [Homo sapiens] 1283 0.0
gi|21327701 TBP-associated factor 15 isoform 1 [Homo sapiens] 1277 0.0
gi|4826734 fusion (involved in t(12;16) in malignant liposarcoma... 405 e-113
gi|253970504 Ewing sarcoma breakpoint region 1 isoform 4 [Homo s... 356 4e-98
gi|253970502 Ewing sarcoma breakpoint region 1 isoform 3 [Homo s... 334 1e-91
gi|4885225 Ewing sarcoma breakpoint region 1 isoform 2 [Homo sap... 334 2e-91
gi|253970500 Ewing sarcoma breakpoint region 1 isoform 1 [Homo s... 332 8e-91
gi|55956899 keratin 9 [Homo sapiens] 157 3e-38
gi|14043070 heterogeneous nuclear ribonucleoprotein A1 isoform b... 147 3e-35
gi|34740329 heterogeneous nuclear ribonucleoprotein A3 [Homo sap... 144 2e-34
gi|62122917 filaggrin family member 2 [Homo sapiens] 129 6e-30
gi|57864582 hornerin [Homo sapiens] 128 2e-29
gi|195972866 keratin 10 [Homo sapiens] 122 7e-28
gi|109255251 loricrin [Homo sapiens] 120 3e-27
gi|109452587 family with sequence similarity 98, member B isofor... 116 7e-26
gi|14043072 heterogeneous nuclear ribonucleoprotein A2/B1 isofor... 114 2e-25
gi|4504447 heterogeneous nuclear ribonucleoprotein A2/B1 isoform... 114 2e-25
gi|56699482 hypothetical protein LOC25940 [Homo sapiens] 112 7e-25
gi|109148552 keratin 3 [Homo sapiens] 107 2e-23
gi|5803036 heterogeneous nuclear ribonucleoprotein A0 [Homo sapi... 102 1e-21
gi|4504445 heterogeneous nuclear ribonucleoprotein A1 isoform a ... 100 5e-21
gi|212549553 interleukin enhancer binding factor 3 isoform d [Ho... 100 6e-21
gi|24234750 interleukin enhancer binding factor 3 isoform a [Hom... 100 6e-21
gi|242117971 RNA binding motif protein, X-linked-like 1 [Homo sa... 99 1e-20
gi|21361809 RNA binding motif protein, X-linked-like 1 [Homo sap... 99 1e-20
gi|56699409 RNA binding motif protein, X-linked [Homo sapiens] 98 2e-20
gi|119395750 keratin 1 [Homo sapiens] 97 5e-20
gi|25777671 protein phosphatase 1, regulatory subunit 10 [Homo s... 96 7e-20
gi|47132620 keratin 2 [Homo sapiens] 96 9e-20
gi|58761498 heterogeneous nuclear ribonucleoprotein A1-like [Hom... 94 3e-19
>gi|4507353 TBP-associated factor 15 isoform 2 [Homo sapiens]
Length = 589
Score = 1283 bits (3319), Expect = 0.0
Identities = 589/589 (100%), Positives = 589/589 (100%)
Query: 1 MSDSGSYGQSGGEQQSYSTYGNPGSQGYGQASQSYSGYGQTTDSSYGQNYSGYSSYGQSY 60
MSDSGSYGQSGGEQQSYSTYGNPGSQGYGQASQSYSGYGQTTDSSYGQNYSGYSSYGQSY
Sbjct: 1 MSDSGSYGQSGGEQQSYSTYGNPGSQGYGQASQSYSGYGQTTDSSYGQNYSGYSSYGQSY 60
Query: 61 SQSYGGYENQKQSSYSQQPYNNQGQQQNMESSGSQGGRAPSYDQPDYGQQDSYDQQSGYD 120
SQSYGGYENQKQSSYSQQPYNNQGQQQNMESSGSQGGRAPSYDQPDYGQQDSYDQQSGYD
Sbjct: 61 SQSYGGYENQKQSSYSQQPYNNQGQQQNMESSGSQGGRAPSYDQPDYGQQDSYDQQSGYD 120
Query: 121 QHQGSYDEQSNYDQQHDSYSQNQQSYHSQRENYSHHTQDDRRDVSRYGEDNRGYGGSQGG 180
QHQGSYDEQSNYDQQHDSYSQNQQSYHSQRENYSHHTQDDRRDVSRYGEDNRGYGGSQGG
Sbjct: 121 QHQGSYDEQSNYDQQHDSYSQNQQSYHSQRENYSHHTQDDRRDVSRYGEDNRGYGGSQGG 180
Query: 181 GRGRGGYDKDGRGPMTGSSGGDRGGFKNFGGHRDYGPRTDADSESDNSDNNTIFVQGLGE 240
GRGRGGYDKDGRGPMTGSSGGDRGGFKNFGGHRDYGPRTDADSESDNSDNNTIFVQGLGE
Sbjct: 181 GRGRGGYDKDGRGPMTGSSGGDRGGFKNFGGHRDYGPRTDADSESDNSDNNTIFVQGLGE 240
Query: 241 GVSTDQVGEFFKQIGIIKTNKKTGKPMINLYTDKDTGKPKGEATVSFDDPPSAKAAIDWF 300
GVSTDQVGEFFKQIGIIKTNKKTGKPMINLYTDKDTGKPKGEATVSFDDPPSAKAAIDWF
Sbjct: 241 GVSTDQVGEFFKQIGIIKTNKKTGKPMINLYTDKDTGKPKGEATVSFDDPPSAKAAIDWF 300
Query: 301 DGKEFHGNIIKVSFATRRPEFMRGGGSGGGRRGRGGYRGRGGFQGRGGDPKSGDWVCPNP 360
DGKEFHGNIIKVSFATRRPEFMRGGGSGGGRRGRGGYRGRGGFQGRGGDPKSGDWVCPNP
Sbjct: 301 DGKEFHGNIIKVSFATRRPEFMRGGGSGGGRRGRGGYRGRGGFQGRGGDPKSGDWVCPNP 360
Query: 361 SCGNMNFARRNSCNQCNEPRPEDSRPSGGDFRGRGYGGERGYRGRGGRGGDRGGYGGDRS 420
SCGNMNFARRNSCNQCNEPRPEDSRPSGGDFRGRGYGGERGYRGRGGRGGDRGGYGGDRS
Sbjct: 361 SCGNMNFARRNSCNQCNEPRPEDSRPSGGDFRGRGYGGERGYRGRGGRGGDRGGYGGDRS 420
Query: 421 GGGYGGDRSSGGGYSGDRSGGGYGGDRSGGGYGGDRGGGYGGDRGGGYGGDRGGGYGGDR 480
GGGYGGDRSSGGGYSGDRSGGGYGGDRSGGGYGGDRGGGYGGDRGGGYGGDRGGGYGGDR
Sbjct: 421 GGGYGGDRSSGGGYSGDRSGGGYGGDRSGGGYGGDRGGGYGGDRGGGYGGDRGGGYGGDR 480
Query: 481 GGYGGDRGGGYGGDRGGYGGDRGGYGGDRGGYGGDRGGYGGDRSRGGYGGDRGGGSGYGG 540
GGYGGDRGGGYGGDRGGYGGDRGGYGGDRGGYGGDRGGYGGDRSRGGYGGDRGGGSGYGG
Sbjct: 481 GGYGGDRGGGYGGDRGGYGGDRGGYGGDRGGYGGDRGGYGGDRSRGGYGGDRGGGSGYGG 540
Query: 541 DRSGGYGGDRSGGGYGGDRGGGYGGDRGGYGGKMGGRNDYRNDQRNRPY 589
DRSGGYGGDRSGGGYGGDRGGGYGGDRGGYGGKMGGRNDYRNDQRNRPY
Sbjct: 541 DRSGGYGGDRSGGGYGGDRGGGYGGDRGGYGGKMGGRNDYRNDQRNRPY 589
>gi|21327701 TBP-associated factor 15 isoform 1 [Homo sapiens]
Length = 592
Score = 1277 bits (3305), Expect = 0.0
Identities = 589/592 (99%), Positives = 589/592 (99%), Gaps = 3/592 (0%)
Query: 1 MSDSGSYGQSGGEQQSYSTYGNPGSQGYGQASQSYSGYGQTTDSSYGQNYSGYSSYGQS- 59
MSDSGSYGQSGGEQQSYSTYGNPGSQGYGQASQSYSGYGQTTDSSYGQNYSGYSSYGQS
Sbjct: 1 MSDSGSYGQSGGEQQSYSTYGNPGSQGYGQASQSYSGYGQTTDSSYGQNYSGYSSYGQSQ 60
Query: 60 --YSQSYGGYENQKQSSYSQQPYNNQGQQQNMESSGSQGGRAPSYDQPDYGQQDSYDQQS 117
YSQSYGGYENQKQSSYSQQPYNNQGQQQNMESSGSQGGRAPSYDQPDYGQQDSYDQQS
Sbjct: 61 SGYSQSYGGYENQKQSSYSQQPYNNQGQQQNMESSGSQGGRAPSYDQPDYGQQDSYDQQS 120
Query: 118 GYDQHQGSYDEQSNYDQQHDSYSQNQQSYHSQRENYSHHTQDDRRDVSRYGEDNRGYGGS 177
GYDQHQGSYDEQSNYDQQHDSYSQNQQSYHSQRENYSHHTQDDRRDVSRYGEDNRGYGGS
Sbjct: 121 GYDQHQGSYDEQSNYDQQHDSYSQNQQSYHSQRENYSHHTQDDRRDVSRYGEDNRGYGGS 180
Query: 178 QGGGRGRGGYDKDGRGPMTGSSGGDRGGFKNFGGHRDYGPRTDADSESDNSDNNTIFVQG 237
QGGGRGRGGYDKDGRGPMTGSSGGDRGGFKNFGGHRDYGPRTDADSESDNSDNNTIFVQG
Sbjct: 181 QGGGRGRGGYDKDGRGPMTGSSGGDRGGFKNFGGHRDYGPRTDADSESDNSDNNTIFVQG 240
Query: 238 LGEGVSTDQVGEFFKQIGIIKTNKKTGKPMINLYTDKDTGKPKGEATVSFDDPPSAKAAI 297
LGEGVSTDQVGEFFKQIGIIKTNKKTGKPMINLYTDKDTGKPKGEATVSFDDPPSAKAAI
Sbjct: 241 LGEGVSTDQVGEFFKQIGIIKTNKKTGKPMINLYTDKDTGKPKGEATVSFDDPPSAKAAI 300
Query: 298 DWFDGKEFHGNIIKVSFATRRPEFMRGGGSGGGRRGRGGYRGRGGFQGRGGDPKSGDWVC 357
DWFDGKEFHGNIIKVSFATRRPEFMRGGGSGGGRRGRGGYRGRGGFQGRGGDPKSGDWVC
Sbjct: 301 DWFDGKEFHGNIIKVSFATRRPEFMRGGGSGGGRRGRGGYRGRGGFQGRGGDPKSGDWVC 360
Query: 358 PNPSCGNMNFARRNSCNQCNEPRPEDSRPSGGDFRGRGYGGERGYRGRGGRGGDRGGYGG 417
PNPSCGNMNFARRNSCNQCNEPRPEDSRPSGGDFRGRGYGGERGYRGRGGRGGDRGGYGG
Sbjct: 361 PNPSCGNMNFARRNSCNQCNEPRPEDSRPSGGDFRGRGYGGERGYRGRGGRGGDRGGYGG 420
Query: 418 DRSGGGYGGDRSSGGGYSGDRSGGGYGGDRSGGGYGGDRGGGYGGDRGGGYGGDRGGGYG 477
DRSGGGYGGDRSSGGGYSGDRSGGGYGGDRSGGGYGGDRGGGYGGDRGGGYGGDRGGGYG
Sbjct: 421 DRSGGGYGGDRSSGGGYSGDRSGGGYGGDRSGGGYGGDRGGGYGGDRGGGYGGDRGGGYG 480
Query: 478 GDRGGYGGDRGGGYGGDRGGYGGDRGGYGGDRGGYGGDRGGYGGDRSRGGYGGDRGGGSG 537
GDRGGYGGDRGGGYGGDRGGYGGDRGGYGGDRGGYGGDRGGYGGDRSRGGYGGDRGGGSG
Sbjct: 481 GDRGGYGGDRGGGYGGDRGGYGGDRGGYGGDRGGYGGDRGGYGGDRSRGGYGGDRGGGSG 540
Query: 538 YGGDRSGGYGGDRSGGGYGGDRGGGYGGDRGGYGGKMGGRNDYRNDQRNRPY 589
YGGDRSGGYGGDRSGGGYGGDRGGGYGGDRGGYGGKMGGRNDYRNDQRNRPY
Sbjct: 541 YGGDRSGGYGGDRSGGGYGGDRGGGYGGDRGGYGGKMGGRNDYRNDQRNRPY 592
>gi|4826734 fusion (involved in t(12;16) in malignant liposarcoma)
[Homo sapiens]
Length = 526
Score = 405 bits (1040), Expect = e-113
Identities = 263/522 (50%), Positives = 295/522 (56%), Gaps = 92/522 (17%)
Query: 15 QSYSTYGNPGSQGYGQAS------QSYSGYGQTTDSS-YGQNYSGYSSYGQSYSQSYG-- 65
QSY Y QGY Q S QSYSGY Q+TD+S YGQ S YSSYGQS + YG
Sbjct: 12 QSYGAYPTQPGQGYSQQSSQPYGQQSYSGYSQSTDTSGYGQ--SSYSSYGQSQNTGYGTQ 69
Query: 66 ------------GYENQKQSSYSQQP-YNNQGQQQNMES-SGSQGG--RAPSYDQPDYG- 108
G QSSY QQ Y GQQ S SGS G ++ SY QP G
Sbjct: 70 STPQGYGSTGGYGSSQSSQSSYGQQSSYPGYGQQPAPSSTSGSYGSSSQSSSYGQPQSGS 129
Query: 109 ---------QQDSYDQQSGYDQHQGSYDEQSNYDQQHD---------SYSQNQQSYHS-- 148
QQ SY QQ Y+ QG Y +Q+ Y+ +Y Q+Q S S
Sbjct: 130 YSQQPSYGGQQQSYGQQQSYNPPQG-YGQQNQYNSSSGGGGGGGGGGNYGQDQSSMSSGG 188
Query: 149 -QRENYSHHTQDDRRDVSRYGEDNRG---YGGSQGGG--------RGRGGYDKDGRGPMT 196
Y + Q YG+ +RG GGS GGG R GGY+ GRG
Sbjct: 189 GSGGGYGNQDQSGGGGSGGYGQQDRGGRGRGGSGGGGGGGGGGYNRSSGGYEPRGRGGGR 248
Query: 197 GSSGG----DRGGFKNFGGHRDYGPRTDADSESDNSDNNTIFVQGLGEGVSTDQVGEFFK 252
G GG DRGGF FGG RD G R D SE DNSDNNTIFVQGLGE V+ + V ++FK
Sbjct: 249 GGRGGMGGSDRGGFNKFGGPRDQGSRHD--SEQDNSDNNTIFVQGLGENVTIESVADYFK 306
Query: 253 QIGIIKTNKKTGKPMINLYTDKDTGKPKGEATVSFDDPPSAKAAIDWFDGKEFHGNIIKV 312
QIGIIKTNKKTG+PMINLYTD++TGK KGEATVSFDDPPSAKAAIDWFDGKEF GN IKV
Sbjct: 307 QIGIIKTNKKTGQPMINLYTDRETGKLKGEATVSFDDPPSAKAAIDWFDGKEFSGNPIKV 366
Query: 313 SFATRRPEFMRGGGSGGGRRGRGGYRGRGGF-------QGRGGDP----------KSGDW 355
SFATRR +F RGGG+G G RGRGG GRGG+ GRGG P ++GDW
Sbjct: 367 SFATRRADFNRGGGNGRGGRGRGGPMGRGGYGGGGSGGGGRGGFPSGGGGGGGQQRAGDW 426
Query: 356 VCPNPSCGNMNFARRNSCNQCNEPRPEDSRPSGGDFRGRGYGGERGYRGRGGRGG-DRGG 414
CPNP+C NMNF+ RN CNQC P+P+ P GG G GG G RGGRGG DRGG
Sbjct: 427 KCPNPTCENMNFSWRNECNQCKAPKPDG--PGGGP-GGSHMGGNYGDDRRGGRGGYDRGG 483
Query: 415 YGGDRSGGGYGGDRSSGGGYSGDRSGGGYGGDRSGGGYGGDR 456
Y G GG GG R GG GDR G G G S G + DR
Sbjct: 484 YRG--RGGDRGGFRGGRGG--GDRGGFGPGKMDSRGEHRQDR 521
Score = 111 bits (277), Expect = 2e-24
Identities = 85/225 (37%), Positives = 98/225 (43%), Gaps = 33/225 (14%)
Query: 382 EDSRPSGGDFRGRGYGGERGYRGRGGRGGDRGGYGGDRSGGGYGGDRSSGGGY----SGD 437
+ S S G + GYG + +G G GG YG +S G +SS GY +
Sbjct: 52 QSSYSSYGQSQNTGYGTQSTPQGYGSTGG----YGSSQSSQSSYGQQSSYPGYGQQPAPS 107
Query: 438 RSGGGYGGDRSGGGYGGDRGGGY------GGDRGG-----GYGGDRGGG----YGGDRGG 482
+ G YG YG + G Y GG + Y +G G Y GG
Sbjct: 108 STSGSYGSSSQSSSYGQPQSGSYSQQPSYGGQQQSYGQQQSYNPPQGYGQQNQYNSSSGG 167
Query: 483 YGGDRGGG-YGGDRGGY---GGDRGGYGGDRGGYGGDRGGYG----GDRSRGGYGGDRGG 534
GG GGG YG D+ GG GGYG GG GGYG G R RGG GG GG
Sbjct: 168 GGGGGGGGNYGQDQSSMSSGGGSGGGYGNQDQSGGGGSGGYGQQDRGGRGRGGSGGGGGG 227
Query: 535 GSGYGGDRSGGYGGDRSGGGYGGDRGGGYGGDRGGYGGKMGGRND 579
G G SGGY GGG GG RGG G DRGG+ K GG D
Sbjct: 228 GGGGYNRSSGGYEPRGRGGGRGG-RGGMGGSDRGGF-NKFGGPRD 270
Score = 106 bits (264), Expect = 7e-23
Identities = 79/224 (35%), Positives = 98/224 (43%), Gaps = 33/224 (14%)
Query: 325 GGSGGGRRGRGGYRGRGGFQGRGGDPKSGDWVCPNPSCGNMNFARRNSCNQCNEPRPEDS 384
GG G + + Y + + G G P P+ + G+ + ++S
Sbjct: 79 GGYGSSQSSQSSYGQQSSYPGYGQQP------APSSTSGSYGSSSQSS------------ 120
Query: 385 RPSGGDFRGRGYGGERGYRGRGGRGGDRGGYGGDRSGGGYGGDRSSGGGYSGDRSGGGYG 444
S G + Y + Y G+ G + Y + G SS GG G GG YG
Sbjct: 121 --SYGQPQSGSYSQQPSYGGQQQSYGQQQSYNPPQGYGQQNQYNSSSGGGGGGGGGGNYG 178
Query: 445 GDRSGGGYGGDRGGGYGGDRGGGYGGDRGGGYGG-DRGGYG-GDRGGGYGGDRGGYGGDR 502
D+S GG GGGYG G GG GGYG DRGG G G GGG GG GGY
Sbjct: 179 QDQSSMSSGGGSGGGYGNQDQSGGGGS--GGYGQQDRGGRGRGGSGGGGGGGGGGYNRSS 236
Query: 503 GGYGGDRGGYGGDRGGYGGDRSRGGYGG-DRGGGSGYGGDRSGG 545
GGY + G GG RGG RGG GG DRGG + +GG R G
Sbjct: 237 GGY--EPRGRGGGRGG------RGGMGGSDRGGFNKFGGPRDQG 272
Score = 94.7 bits (234), Expect = 2e-19
Identities = 70/158 (44%), Positives = 77/158 (48%), Gaps = 46/158 (29%)
Query: 471 DRGGGYGGDRGGYGGDRGGGYGGDRGGYGGDRGGYGGDRGGYGGDRGGYGGDRSRG---- 526
+RGGG G RGG G RGG G RGGYGG G GG RGG+ GG GG + G
Sbjct: 376 NRGGGNG--RGGRG--RGGPMG--RGGYGGGGSG-GGGRGGFPSGGGGGGGQQRAGDWKC 428
Query: 527 -------------------------GYGGDRGG---GSGYGGDRSGGYGG-DRS-----G 552
G GG GG G YG DR GG GG DR G
Sbjct: 429 PNPTCENMNFSWRNECNQCKAPKPDGPGGGPGGSHMGGNYGDDRRGGRGGYDRGGYRGRG 488
Query: 553 GGYGGDRGGGYGGDRGGYG-GKMGGRNDYRNDQRNRPY 589
G GG RGG GGDRGG+G GKM R ++R D+R RPY
Sbjct: 489 GDRGGFRGGRGGGDRGGFGPGKMDSRGEHRQDRRERPY 526
Score = 63.5 bits (153), Expect = 5e-10
Identities = 91/335 (27%), Positives = 130/335 (38%), Gaps = 66/335 (19%)
Query: 111 DSYDQQSGYDQHQGSYDEQ--SNYDQQHDS-YSQNQQSYHSQRENYSHHTQDDRRDVSRY 167
+ Y QQ+ Q G+Y Q Y QQ Y Q S +SQ + S + Q S Y
Sbjct: 4 NDYTQQA--TQSYGAYPTQPGQGYSQQSSQPYGQQSYSGYSQSTDTSGYGQS---SYSSY 58
Query: 168 GE-DNRGYGGSQGGGRGRGGYDKDGRGPMTGSSGGDRGGFKNFGGHRDYGPRTDADSESD 226
G+ N GY G+Q +G G G + SS G + + +G + P + + S
Sbjct: 59 GQSQNTGY-GTQSTPQGYGSTGGYGSSQSSQSSYGQQSSYPGYG--QQPAPSSTSGSYGS 115
Query: 227 NSDNNTIFVQGLGEGVSTDQVGEFFKQIGIIKT-NKKTGKPMINLYTDKDTGKPKGEATV 285
+S +++ G G + G ++ N G N Y G G
Sbjct: 116 SSQSSSYGQPQSGSYSQQPSYGGQQQSYGQQQSYNPPQGYGQQNQYNSSSGGGGGGGGGG 175
Query: 286 SFDDPPSAKAAIDWFDGKEFHGNIIKVSFATRRPEFMRGGGSGG-GRRGRGGYRGRGGFQ 344
++ S+ ++ G +GN + GGGSGG G++ RGG RGRGG
Sbjct: 176 NYGQDQSSMSSGGGSGGG--YGN----------QDQSGGGGSGGYGQQDRGG-RGRGGSG 222
Query: 345 GRGGDPKSGDWVCPNPSCGNMNFARRNSCNQCNEPRPEDSRPSGGDFRGRGYGGERGYRG 404
G GG G +R SGG + RG GG RG G
Sbjct: 223 GGGGGGGGG-----------------------------YNRSSGG-YEPRGRGGGRG--G 250
Query: 405 RGGRGG-DRGGYGGDRSGGGYGGDRSSGGGYSGDR 438
RGG GG DRGG+ +GG R G + ++
Sbjct: 251 RGGMGGSDRGGF------NKFGGPRDQGSRHDSEQ 279
Score = 60.5 bits (145), Expect = 4e-09
Identities = 55/206 (26%), Positives = 63/206 (30%), Gaps = 34/206 (16%)
Query: 415 YGGDRSGGGYGGDRSSGGGYSGDRSGGGYGGDRSGGGYGGDRGGGYGGDRGGGYGGDRGG 474
YG + G G + S Y G +S GY GYG YG + GYG
Sbjct: 14 YGAYPTQPGQGYSQQSSQPY-GQQSYSGYSQSTDTSGYGQSSYSSYGQSQNTGYGTQSTP 72
Query: 475 GYGGDRGGYGGDRGG-----------GYG------GDRGGYGGDR--GGYGGDRGGYGGD 515
G GGYG + GYG G YG YG + G
Sbjct: 73 QGYGSTGGYGSSQSSQSSYGQQSSYPGYGQQPAPSSTSGSYGSSSQSSSYGQPQSGSYSQ 132
Query: 516 RGGYGGDRSRGGYGGDRGGGSGYGGDRSGGYGGDRSGGGYGGDR--------------GG 561
+ YGG + G GYG GGG GG GG
Sbjct: 133 QPSYGGQQQSYGQQQSYNPPQGYGQQNQYNSSSGGGGGGGGGGNYGQDQSSMSSGGGSGG 192
Query: 562 GYGGDRGGYGGKMGGRNDYRNDQRNR 587
GYG GG GG R R
Sbjct: 193 GYGNQDQSGGGGSGGYGQQDRGGRGR 218
Score = 38.9 bits (89), Expect = 0.013
Identities = 25/53 (47%), Positives = 29/53 (54%), Gaps = 7/53 (13%)
Query: 522 DRSRGGYGGDRGGGSGYGGDRS-GGYGGDRSGGGYGGDRGGGYGGDRGGYGGK 573
D +RGG G+ GG G GG GGYGG GG GG GG+ GG GG+
Sbjct: 374 DFNRGG--GNGRGGRGRGGPMGRGGYGG----GGSGGGGRGGFPSGGGGGGGQ 420
Score = 33.5 bits (75), Expect = 0.56
Identities = 18/36 (50%), Positives = 20/36 (55%), Gaps = 1/36 (2%)
Query: 541 DRSGGYGGDRSGGGYGGDRG-GGYGGDRGGYGGKMG 575
D + G G R G G GG G GGYGG G GG+ G
Sbjct: 374 DFNRGGGNGRGGRGRGGPMGRGGYGGGGSGGGGRGG 409
>gi|253970504 Ewing sarcoma breakpoint region 1 isoform 4 [Homo
sapiens]
Length = 600
Score = 356 bits (913), Expect = 4e-98
Identities = 242/571 (42%), Positives = 299/571 (52%), Gaps = 110/571 (19%)
Query: 14 QQSYSTYGNPGSQGYGQASQSYSGYGQTT-DSSYGQNYSGYSS--YGQSYSQSYGGYEN- 69
QQSY TYG P Y QA Q+ + YGQT +SYGQ +GY++ Q+YSQ GY
Sbjct: 38 QQSYGTYGQPTDVSYTQA-QTTATYGQTAYATSYGQPPTGYTTPTAPQAYSQPVQGYGTG 96
Query: 70 ----------------QKQSSYSQQP-YNNQGQQQNMESSGSQGGRAP-SYDQPDYGQQD 111
QS+Y QP Y GQQ + S P SYDQ Y QQ+
Sbjct: 97 AYDTTTATVTTTQASYAAQSAYGTQPAYPAYGQQPAATAPTSYSSTQPTSYDQSSYSQQN 156
Query: 112 SYDQQSGYDQHQGSYDEQSNYDQQHD--------SYSQNQQSYHSQRENYSHHT---QDD 160
+Y Q S Y Q Q SY +QS+Y QQ SYSQ Y Q +Y + QD
Sbjct: 157 TYGQPSSYGQ-QSSYGQQSSYGQQPPTSYPPQTGSYSQAPSQYSQQSSSYGQQSSFRQDH 215
Query: 161 RRDVSRYGEDNRGYGG-----SQGG----GRGRGGYDKDG--RGPMTGSSGG-----DRG 204
+ YG+++ G+ G S G GRGRGG+D+ G RG G GG +RG
Sbjct: 216 PSSMGVYGQESGGFSGPGENRSMSGPDNRGRGRGGFDRGGMSRGGRGGGRGGMGSAGERG 275
Query: 205 GFKNFGGHRDYGPRTDADSESD---NSDNNTIFVQGLGEGVSTDQVGEFFKQIGIIKTNK 261
GF GG D GP D D +SDN+ I+VQGL + V+ D + +FFKQ G++K NK
Sbjct: 276 GFNKPGGPMDEGPDLDLGPPVDPDEDSDNSAIYVQGLNDSVTLDDLADFFKQCGVVKMNK 335
Query: 262 KTGKPMINLYTDKDTGKPKGEATVSFDDPPSAKAAIDWFDGKEFHGNIIKVSFATRRPEF 321
+TG+PMI++Y DK+TGKPKG+ATVS++DPP+AKAA++WFDGK+F G+ +KVS A ++P
Sbjct: 336 RTGQPMIHIYLDKETGKPKGDATVSYEDPPTAKAAVEWFDGKDFQGSKLKVSLARKKPPM 395
Query: 322 --MRGG--------------------GSGGGRRGRGGYRG--RGGFQGRG-----GDP-- 350
MRGG G GG GR G RG RGGF RG G+P
Sbjct: 396 NSMRGGLPPREGRGMPPPLRGGPGGPGGPGGPMGRMGGRGGDRGGFPPRGPRGSRGNPSG 455
Query: 351 ------KSGDWVCPNPSCGNMNFARRNSCNQCNEPRPEDSRPSGGDFRGRGYGGERGYRG 404
++GDW CPNP CGN NFA R CNQC P+PE P + G RG
Sbjct: 456 GGNVQHRAGDWQCPNPGCGNQNFAWRTECNQCKAPKPEGFLPP-------PFPPPGGDRG 508
Query: 405 RGGRGGDRGGYGGDRSGGGYGGDRSSGGGYSGDRSG--GGYGGDRSGGGYGGDRGGGYGG 462
RGG GG RGG GG GG GG GG GDR G GG G DR GG+GG R GG GG
Sbjct: 509 RGGPGGMRGGRGGLMDRGGPGG--MFRGGRGGDRGGFRGGRGMDR--GGFGGGRRGGPGG 564
Query: 463 DRG------GGYGGDRGGGYGGDRGGYGGDR 487
G GG G RGG D+G + +R
Sbjct: 565 PPGPLMEQMGGRRGGRGGPGKMDKGEHRQER 595
Score = 90.5 bits (223), Expect = 4e-18
Identities = 82/214 (38%), Positives = 93/214 (43%), Gaps = 34/214 (15%)
Query: 397 GGERGYRGRGGRGGDRGGYGGDRSGGGYGGDRSSGGGYSGDRSGGGYGGDRSGGGYGGDR 456
GG GRG RGG GG GG GG GG GDR G G R G G
Sbjct: 400 GGLPPREGRGMPPPLRGGPGGP---GGPGGPMGRMGGRGGDRGGFPPRGPR--GSRGNPS 454
Query: 457 GGGYGGDRGGGYGGDRGGGYGGDRGGYGGDRGGGYGGDRGGY--------GGDRGGYGGD 508
GGG R G + G G + + G+ GGDRG
Sbjct: 455 GGGNVQHRAGDWQCPNPG-CGNQNFAWRTECNQCKAPKPEGFLPPPFPPPGGDRG----- 508
Query: 509 RGGYGGDRGGYGGDRSRGGYGG-DRGGGSGYGGDRSGGYGGDRSGGGYGGDRGGGYGGDR 567
RGG GG RGG GG RGG GG RGG G G GG G DR GG+GG R GG GG
Sbjct: 509 RGGPGGMRGGRGGLMDRGGPGGMFRGGRGGDRGGFRGGRGMDR--GGFGGGRRGGPGGPP 566
Query: 568 G----GYGGKMGGR--------NDYRNDQRNRPY 589
G GG+ GGR ++R ++R+RPY
Sbjct: 567 GPLMEQMGGRRGGRGGPGKMDKGEHRQERRDRPY 600
Score = 49.3 bits (116), Expect = 1e-05
Identities = 38/105 (36%), Positives = 44/105 (41%), Gaps = 5/105 (4%)
Query: 478 GDRGGYGGDRGGGYGGDRGGYGGDRGGYGGDRGGYGGDRGGYGGDR--SRGGYGGDRGGG 535
G + YG Y G Y Y YG + + D S G YG + GG
Sbjct: 171 GQQSSYGQQPPTSYPPQTGSYSQAPSQYSQQSSSYG-QQSSFRQDHPSSMGVYGQESGGF 229
Query: 536 SGYGGDRSGGYGGDRSGGGYGG-DRGGGYGGDRGGYGGKMGGRND 579
SG G +RS G D G G GG DRGG G RGG G MG +
Sbjct: 230 SGPGENRSMS-GPDNRGRGRGGFDRGGMSRGGRGGGRGGMGSAGE 273
Score = 47.8 bits (112), Expect = 3e-05
Identities = 39/116 (33%), Positives = 44/116 (37%), Gaps = 10/116 (8%)
Query: 468 YGGDRGGGYGGDRGGYGGDRGGGYGGDRGGYGGD---RGGYGGDRGGYGGDRGGYGGDRS 524
YG Y G Y Y YG R + G YG + GG+ G
Sbjct: 176 YGQQPPTSYPPQTGSYS-QAPSQYSQQSSSYGQQSSFRQDHPSSMGVYGQESGGFSGPGE 234
Query: 525 RGGYGGDRGGGSGYGGDRSGGYGGDRSGGGYGGDRGG-GYGGDRGGYGGKMGGRND 579
G G G GG GG S GG GG RGG G G+RGG+ K GG D
Sbjct: 235 NRSMSGPDNRGRGRGGFDRGG----MSRGGRGGGRGGMGSAGERGGF-NKPGGPMD 285
Score = 45.8 bits (107), Expect = 1e-04
Identities = 35/70 (50%), Positives = 39/70 (55%), Gaps = 11/70 (15%)
Query: 466 GGYGGDRGG--GYGGDRGGYGGD-RGGGYGG-DRGGYGGDRGGYGGDRGGYG--GDRGGY 519
G YG + GG G G +R G D RG G GG DRGG RGG GG RGG G G+RGG+
Sbjct: 220 GVYGQESGGFSGPGENRSMSGPDNRGRGRGGFDRGGMS--RGGRGGGRGGMGSAGERGGF 277
Query: 520 ---GGDRSRG 526
GG G
Sbjct: 278 NKPGGPMDEG 287
Score = 44.3 bits (103), Expect = 3e-04
Identities = 38/88 (43%), Positives = 42/88 (47%), Gaps = 11/88 (12%)
Query: 424 YGGDRSSGGGYSGDR----SGGGYGGDRSGG--GYGGDRGGGYGGDRGGGYGG-DRGGGY 476
Y SS G S R S G G SGG G G +R +RG G GG DRGG
Sbjct: 198 YSQQSSSYGQQSSFRQDHPSSMGVYGQESGGFSGPGENRSMSGPDNRGRGRGGFDRGGM- 256
Query: 477 GGDRGGYGGDRGG-GYGGDRGGYGGDRG 503
RGG GG RGG G G+RGG+ G
Sbjct: 257 --SRGGRGGGRGGMGSAGERGGFNKPGG 282
Score = 43.5 bits (101), Expect = 5e-04
Identities = 31/74 (41%), Positives = 37/74 (50%), Gaps = 8/74 (10%)
Query: 474 GGYGGDRGGYGG--DRGGGYGGDRGGYGGDRGGYGGDRGGYGGDRGGYGGDRSRGGYGGD 531
G YG + GG+ G + G D G G RGG+ DRGG RGG GG R G G+
Sbjct: 220 GVYGQESGGFSGPGENRSMSGPDNRGRG--RGGF--DRGGMS--RGGRGGGRGGMGSAGE 273
Query: 532 RGGGSGYGGDRSGG 545
RGG + GG G
Sbjct: 274 RGGFNKPGGPMDEG 287
Score = 42.7 bits (99), Expect = 0.001
Identities = 31/71 (43%), Positives = 35/71 (49%), Gaps = 8/71 (11%)
Query: 420 SGGGYGGDRSSGGGYSGDRSGGGYGG-DRSGGGYGG-DRGGGYGGDRGGGYGGDRGGGYG 477
S G YG + GG+SG G D G G GG DRGG G RGGG G G G
Sbjct: 218 SMGVYGQE---SGGFSGPGENRSMSGPDNRGRGRGGFDRGGMSRGGRGGGRG---GMGSA 271
Query: 478 GDRGGYGGDRG 488
G+RGG+ G
Sbjct: 272 GERGGFNKPGG 282
Score = 42.4 bits (98), Expect = 0.001
Identities = 31/68 (45%), Positives = 36/68 (52%), Gaps = 8/68 (11%)
Query: 448 SGGGYGGDRGG--GYGGDRGGGYGGDRGGGYGG-DRGGYGGDRGGGYGGDRGGYG--GDR 502
S G YG + GG G G +R +RG G GG DRGG GG GG RGG G G+R
Sbjct: 218 SMGVYGQESGGFSGPGENRSMSGPDNRGRGRGGFDRGGMSR---GGRGGGRGGMGSAGER 274
Query: 503 GGYGGDRG 510
GG+ G
Sbjct: 275 GGFNKPGG 282
Score = 40.8 bits (94), Expect = 0.004
Identities = 32/74 (43%), Positives = 35/74 (47%), Gaps = 7/74 (9%)
Query: 496 GGYGGDRGGYGGDRGGYGGDRGGYGGD-RSRGGYGGDRGGGSGYGGDRSGGYGGDRSGGG 554
G YG + GG+ G G +R G D R RG G DRGG S G R GG GG S G
Sbjct: 220 GVYGQESGGFSGP----GENRSMSGPDNRGRGRGGFDRGGMSR--GGRGGGRGGMGSAGE 273
Query: 555 YGGDRGGGYGGDRG 568
GG G D G
Sbjct: 274 RGGFNKPGGPMDEG 287
>gi|253970502 Ewing sarcoma breakpoint region 1 isoform 3 [Homo
sapiens]
Length = 655
Score = 334 bits (857), Expect = 1e-91
Identities = 243/626 (38%), Positives = 303/626 (48%), Gaps = 165/626 (26%)
Query: 14 QQSYSTYGNPGSQGYGQASQSYSGYGQTT-DSSYGQNYSGYSS--YGQSYSQSY-----G 65
QQSY TYG P Y QA Q+ + YGQT +SYGQ +GY++ Q+YSQ G
Sbjct: 38 QQSYGTYGQPTDVSYTQA-QTTATYGQTAYATSYGQPPTGYTTPTAPQAYSQPVQGYGTG 96
Query: 66 GYENQK------------QSSYSQQP-YNNQGQQ----------------QNMESSGSQG 96
Y+ QS+Y QP Y GQQ + + S G
Sbjct: 97 AYDTTTATVTTTQASYAAQSAYGTQPAYPAYGQQPAATAPTRPQDGNKPTETSQPQSSTG 156
Query: 97 G-----------------------------------------RAPSYDQPDYGQQDSYDQ 115
G + SYDQ Y QQ++Y Q
Sbjct: 157 GYNQPSLGYGQSNYSYPQVPGSYPMQPVTAPPSYPPTSYSSTQPTSYDQSSYSQQNTYGQ 216
Query: 116 QSGYDQHQGSYDEQSNYDQQHD--------SYSQNQQSYHSQRENYSHHT---QDDRRDV 164
S Y Q Q SY +QS+Y QQ SYSQ Y Q +Y + QD +
Sbjct: 217 PSSYGQ-QSSYGQQSSYGQQPPTSYPPQTGSYSQAPSQYSQQSSSYGQQSSFRQDHPSSM 275
Query: 165 SRYGEDNRGYGG-----SQGG----GRGRGGYDKDG--RGPMTGSSGG----DRGGFKNF 209
YG+++ G+ G S G GRGRGG+D+ G RG G GG +RGGF
Sbjct: 276 GVYGQESGGFSGPGENRSMSGPDNRGRGRGGFDRGGMSRGGRGGGRGGMGAGERGGFNKP 335
Query: 210 GGHRDYGPRTDADSESD---NSDNNTIFVQGLGEGVSTDQVGEFFKQIGIIKTNKKTGKP 266
GG D GP D D +SDN+ I+VQGL + V+ D + +FFKQ G++K NK+TG+P
Sbjct: 336 GGPMDEGPDLDLGPPVDPDEDSDNSAIYVQGLNDSVTLDDLADFFKQCGVVKMNKRTGQP 395
Query: 267 MINLYTDKDTGKPKGEATVSFDDPPSAKAAIDWFDGKEFHGNIIKVSFATRRPEF--MRG 324
MI++Y DK+TGKPKG+ATVS++DPP+AKAA++WFDGK+F G+ +KVS A ++P MRG
Sbjct: 396 MIHIYLDKETGKPKGDATVSYEDPPTAKAAVEWFDGKDFQGSKLKVSLARKKPPMNSMRG 455
Query: 325 G--------------------GSGGGRRGRGGYRG--RGGFQGRG-----GDP------- 350
G G GG GR G RG RGGF RG G+P
Sbjct: 456 GLPPREGRGMPPPLRGGPGGPGGPGGPMGRMGGRGGDRGGFPPRGPRGSRGNPSGGGNVQ 515
Query: 351 -KSGDWVCPNPSCGNMNFARRNSCNQCNEPRPEDSRPSGGDFRGRGYGGERGYRGRGGRG 409
++GDW CPNP CGN NFA R CNQC P+PE P + G RGRGG G
Sbjct: 516 HRAGDWQCPNPGCGNQNFAWRTECNQCKAPKPEGFLPP-------PFPPPGGDRGRGGPG 568
Query: 410 GDRGGYGGDRSGGGYGGDRSSGGGYSGDRSG--GGYGGDRSGGGYGGDRGGGYGGDRG-- 465
G RGG GG GG GG GG GDR G GG G DR GG+GG R GG GG G
Sbjct: 569 GMRGGRGGLMDRGGPGG--MFRGGRGGDRGGFRGGRGMDR--GGFGGGRRGGPGGPPGPL 624
Query: 466 ----GGYGGDRGGGYGGDRGGYGGDR 487
GG G RGG D+G + +R
Sbjct: 625 MEQMGGRRGGRGGPGKMDKGEHRQER 650
Score = 115 bits (289), Expect = 9e-26
Identities = 180/700 (25%), Positives = 241/700 (34%), Gaps = 160/700 (22%)
Query: 2 SDSGSYGQSGGEQQSYSTYGNPGSQGYGQASQ-----SYSGYGQTTDSSYGQNYS----G 52
+D +Y Q+ QQ YS Y +QGY Q +Q SY YGQ TD SY Q + G
Sbjct: 4 TDYSTYSQAAA-QQGYSAYTAQPTQGYAQTTQAYGQQSYGTYGQPTDVSYTQAQTTATYG 62
Query: 53 YSSYGQSYSQSYGGYENQKQSSYSQQPYNNQGQQQNMESSGSQGGRAPSYDQPDYGQQDS 112
++Y SY Q GY QP G ++ + + Q Y Q +
Sbjct: 63 QTAYATSYGQPPTGYTTPTAPQAYSQPVQGYGTGAYDTTTATV-----TTTQASYAAQSA 117
Query: 113 YDQQSGYDQHQGSYDEQSNYDQQHDSYSQNQQSYHSQRENYSHHTQDDRRDVSRYGEDNR 172
Y Q Y Y QQ + + + Q N T + Y + +
Sbjct: 118 YGTQPAYPA----------YGQQPAATAPTRP----QDGNKPTETSQPQSSTGGYNQPSL 163
Query: 173 GYGGSQGG-GRGRGGYDKDGRGPMTGSSGGDRGGFKNFGGHRDYGPRTDADSESDNSDNN 231
GYG S + G Y P+T Y P + + ++ + D +
Sbjct: 164 GYGQSNYSYPQVPGSYPMQ---PVTAPPS--------------YPPTSYSSTQPTSYDQS 206
Query: 232 TIFVQGL-GEGVSTDQVGEFFKQIGIIKTNKKTGKPMINLYTDKDT-----GKPKGEATV 285
+ Q G+ S Q + +Q + + P Y+ + G+ +
Sbjct: 207 SYSQQNTYGQPSSYGQQSSYGQQSSYGQQPPTSYPPQTGSYSQAPSQYSQQSSSYGQQSS 266
Query: 286 SFDDPPSAKAAIDWFDGKEFHGNIIKVSFA------TRRPEFMRGG----GSGGGRRG-- 333
D PS+ G F G S + R F RGG G GGGR G
Sbjct: 267 FRQDHPSSMGVYGQESGG-FSGPGENRSMSGPDNRGRGRGGFDRGGMSRGGRGGGRGGMG 325
Query: 334 ---RGGYRGRGGFQGRGGDPKSGDWVCPNPS--------------------------CGN 364
RGG+ GG G D G V P+ CG
Sbjct: 326 AGERGGFNKPGGPMDEGPDLDLGPPVDPDEDSDNSAIYVQGLNDSVTLDDLADFFKQCGV 385
Query: 365 MNFARRNSCNQCNEPRPEDSRPSGGD-----------------FRGRGYGGER------- 400
+ +R + +++ GD F G+ + G +
Sbjct: 386 VKMNKRTGQPMIHIYLDKETGKPKGDATVSYEDPPTAKAAVEWFDGKDFQGSKLKVSLAR 445
Query: 401 ----------GYRGRGGRGGDRGGYGGDRSGGGYGGDRSSGGGYSGDRSGGGYGGDRSGG 450
G R GRG GG GG GG GG GDR G G R G
Sbjct: 446 KKPPMNSMRGGLPPREGRGMPPPLRGGPGGPGGPGGPMGRMGGRGGDRGGFPPRGPR--G 503
Query: 451 GYGGDRGGGYGGDRGGGYGGDRGGGYGGDRGGYGGDRGGGYGGDRGGY--------GGDR 502
G GGG R G + G G + + G+ GGDR
Sbjct: 504 SRGNPSGGGNVQHRAGDWQCPNPG-CGNQNFAWRTECNQCKAPKPEGFLPPPFPPPGGDR 562
Query: 503 GGYGGDRGGYGGDRGGYGGDRSRGGYGG-DRGGGSGYGGDRSGGYGGDRSGGGYGGDRGG 561
G RGG GG RGG GG RGG GG RGG G G GG G DR GG+GG R G
Sbjct: 563 G-----RGGPGGMRGGRGGLMDRGGPGGMFRGGRGGDRGGFRGGRGMDR--GGFGGGRRG 615
Query: 562 GYGGDRG----GYGGKMGGR--------NDYRNDQRNRPY 589
G GG G GG+ GGR ++R ++R+RPY
Sbjct: 616 GPGGPPGPLMEQMGGRRGGRGGPGKMDKGEHRQERRDRPY 655
>gi|4885225 Ewing sarcoma breakpoint region 1 isoform 2 [Homo
sapiens]
Length = 656
Score = 334 bits (856), Expect = 2e-91
Identities = 243/627 (38%), Positives = 303/627 (48%), Gaps = 166/627 (26%)
Query: 14 QQSYSTYGNPGSQGYGQASQSYSGYGQTT-DSSYGQNYSGYSS--YGQSYSQSY-----G 65
QQSY TYG P Y QA Q+ + YGQT +SYGQ +GY++ Q+YSQ G
Sbjct: 38 QQSYGTYGQPTDVSYTQA-QTTATYGQTAYATSYGQPPTGYTTPTAPQAYSQPVQGYGTG 96
Query: 66 GYENQK------------QSSYSQQP-YNNQGQQ----------------QNMESSGSQG 96
Y+ QS+Y QP Y GQQ + + S G
Sbjct: 97 AYDTTTATVTTTQASYAAQSAYGTQPAYPAYGQQPAATAPTRPQDGNKPTETSQPQSSTG 156
Query: 97 G-----------------------------------------RAPSYDQPDYGQQDSYDQ 115
G + SYDQ Y QQ++Y Q
Sbjct: 157 GYNQPSLGYGQSNYSYPQVPGSYPMQPVTAPPSYPPTSYSSTQPTSYDQSSYSQQNTYGQ 216
Query: 116 QSGYDQHQGSYDEQSNYDQQHD--------SYSQNQQSYHSQRENYSHHT---QDDRRDV 164
S Y Q Q SY +QS+Y QQ SYSQ Y Q +Y + QD +
Sbjct: 217 PSSYGQ-QSSYGQQSSYGQQPPTSYPPQTGSYSQAPSQYSQQSSSYGQQSSFRQDHPSSM 275
Query: 165 SRYGEDNRGYGG-----SQGG----GRGRGGYDKDG--RGPMTGSSGG-----DRGGFKN 208
YG+++ G+ G S G GRGRGG+D+ G RG G GG +RGGF
Sbjct: 276 GVYGQESGGFSGPGENRSMSGPDNRGRGRGGFDRGGMSRGGRGGGRGGMGSAGERGGFNK 335
Query: 209 FGGHRDYGPRTDADSESD---NSDNNTIFVQGLGEGVSTDQVGEFFKQIGIIKTNKKTGK 265
GG D GP D D +SDN+ I+VQGL + V+ D + +FFKQ G++K NK+TG+
Sbjct: 336 PGGPMDEGPDLDLGPPVDPDEDSDNSAIYVQGLNDSVTLDDLADFFKQCGVVKMNKRTGQ 395
Query: 266 PMINLYTDKDTGKPKGEATVSFDDPPSAKAAIDWFDGKEFHGNIIKVSFATRRPEF--MR 323
PMI++Y DK+TGKPKG+ATVS++DPP+AKAA++WFDGK+F G+ +KVS A ++P MR
Sbjct: 396 PMIHIYLDKETGKPKGDATVSYEDPPTAKAAVEWFDGKDFQGSKLKVSLARKKPPMNSMR 455
Query: 324 GG--------------------GSGGGRRGRGGYRG--RGGFQGRG-----GDP------ 350
GG G GG GR G RG RGGF RG G+P
Sbjct: 456 GGLPPREGRGMPPPLRGGPGGPGGPGGPMGRMGGRGGDRGGFPPRGPRGSRGNPSGGGNV 515
Query: 351 --KSGDWVCPNPSCGNMNFARRNSCNQCNEPRPEDSRPSGGDFRGRGYGGERGYRGRGGR 408
++GDW CPNP CGN NFA R CNQC P+PE P + G RGRGG
Sbjct: 516 QHRAGDWQCPNPGCGNQNFAWRTECNQCKAPKPEGFLPP-------PFPPPGGDRGRGGP 568
Query: 409 GGDRGGYGGDRSGGGYGGDRSSGGGYSGDRSG--GGYGGDRSGGGYGGDRGGGYGGDRG- 465
GG RGG GG GG GG GG GDR G GG G DR GG+GG R GG GG G
Sbjct: 569 GGMRGGRGGLMDRGGPGG--MFRGGRGGDRGGFRGGRGMDR--GGFGGGRRGGPGGPPGP 624
Query: 466 -----GGYGGDRGGGYGGDRGGYGGDR 487
GG G RGG D+G + +R
Sbjct: 625 LMEQMGGRRGGRGGPGKMDKGEHRQER 651
Score = 115 bits (288), Expect = 1e-25
Identities = 180/701 (25%), Positives = 241/701 (34%), Gaps = 161/701 (22%)
Query: 2 SDSGSYGQSGGEQQSYSTYGNPGSQGYGQASQ-----SYSGYGQTTDSSYGQNYS----G 52
+D +Y Q+ QQ YS Y +QGY Q +Q SY YGQ TD SY Q + G
Sbjct: 4 TDYSTYSQAAA-QQGYSAYTAQPTQGYAQTTQAYGQQSYGTYGQPTDVSYTQAQTTATYG 62
Query: 53 YSSYGQSYSQSYGGYENQKQSSYSQQPYNNQGQQQNMESSGSQGGRAPSYDQPDYGQQDS 112
++Y SY Q GY QP G ++ + + Q Y Q +
Sbjct: 63 QTAYATSYGQPPTGYTTPTAPQAYSQPVQGYGTGAYDTTTATV-----TTTQASYAAQSA 117
Query: 113 YDQQSGYDQHQGSYDEQSNYDQQHDSYSQNQQSYHSQRENYSHHTQDDRRDVSRYGEDNR 172
Y Q Y Y QQ + + + Q N T + Y + +
Sbjct: 118 YGTQPAYPA----------YGQQPAATAPTRP----QDGNKPTETSQPQSSTGGYNQPSL 163
Query: 173 GYGGSQGG-GRGRGGYDKDGRGPMTGSSGGDRGGFKNFGGHRDYGPRTDADSESDNSDNN 231
GYG S + G Y P+T Y P + + ++ + D +
Sbjct: 164 GYGQSNYSYPQVPGSYPMQ---PVTAPPS--------------YPPTSYSSTQPTSYDQS 206
Query: 232 TIFVQGL-GEGVSTDQVGEFFKQIGIIKTNKKTGKPMINLYTDKDT-----GKPKGEATV 285
+ Q G+ S Q + +Q + + P Y+ + G+ +
Sbjct: 207 SYSQQNTYGQPSSYGQQSSYGQQSSYGQQPPTSYPPQTGSYSQAPSQYSQQSSSYGQQSS 266
Query: 286 SFDDPPSAKAAIDWFDGKEFHGNIIKVSFA------TRRPEFMRGG----GSGGGRRG-- 333
D PS+ G F G S + R F RGG G GGGR G
Sbjct: 267 FRQDHPSSMGVYGQESGG-FSGPGENRSMSGPDNRGRGRGGFDRGGMSRGGRGGGRGGMG 325
Query: 334 ----RGGYRGRGGFQGRGGDPKSGDWVCPNPS--------------------------CG 363
RGG+ GG G D G V P+ CG
Sbjct: 326 SAGERGGFNKPGGPMDEGPDLDLGPPVDPDEDSDNSAIYVQGLNDSVTLDDLADFFKQCG 385
Query: 364 NMNFARRNSCNQCNEPRPEDSRPSGGD-----------------FRGRGYGGER------ 400
+ +R + +++ GD F G+ + G +
Sbjct: 386 VVKMNKRTGQPMIHIYLDKETGKPKGDATVSYEDPPTAKAAVEWFDGKDFQGSKLKVSLA 445
Query: 401 -----------GYRGRGGRGGDRGGYGGDRSGGGYGGDRSSGGGYSGDRSGGGYGGDRSG 449
G R GRG GG GG GG GG GDR G G R
Sbjct: 446 RKKPPMNSMRGGLPPREGRGMPPPLRGGPGGPGGPGGPMGRMGGRGGDRGGFPPRGPR-- 503
Query: 450 GGYGGDRGGGYGGDRGGGYGGDRGGGYGGDRGGYGGDRGGGYGGDRGGY--------GGD 501
G G GGG R G + G G + + G+ GGD
Sbjct: 504 GSRGNPSGGGNVQHRAGDWQCPNPG-CGNQNFAWRTECNQCKAPKPEGFLPPPFPPPGGD 562
Query: 502 RGGYGGDRGGYGGDRGGYGGDRSRGGYGG-DRGGGSGYGGDRSGGYGGDRSGGGYGGDRG 560
RG RGG GG RGG GG RGG GG RGG G G GG G DR GG+GG R
Sbjct: 563 RG-----RGGPGGMRGGRGGLMDRGGPGGMFRGGRGGDRGGFRGGRGMDR--GGFGGGRR 615
Query: 561 GGYGGDRG----GYGGKMGGR--------NDYRNDQRNRPY 589
GG GG G GG+ GGR ++R ++R+RPY
Sbjct: 616 GGPGGPPGPLMEQMGGRRGGRGGPGKMDKGEHRQERRDRPY 656
>gi|253970500 Ewing sarcoma breakpoint region 1 isoform 1 [Homo
sapiens]
Length = 661
Score = 332 bits (850), Expect = 8e-91
Identities = 229/558 (41%), Positives = 282/558 (50%), Gaps = 100/558 (17%)
Query: 14 QQSY---STYGN-PGSQGYGQA------SQSYSGYGQTTDSSYGQNYSGYSSYGQSYSQS 63
Q SY S YG P YGQ ++ G T S + GY+ Y QS
Sbjct: 115 QASYAAQSAYGTQPAYPAYGQQPAATAPTRPQDGNKPTETSQPQSSTGGYNQPSLGYGQS 174
Query: 64 YGGYENQKQSSYSQQPYNNQGQQQNMESSGSQGGRAPSYDQPDYGQQDSYDQQSGYDQHQ 123
Y Q SY QP S +Q SYDQ Y QQ++Y Q S Y Q Q
Sbjct: 175 NYSYP-QVPGSYPMQPVTAPPSYPPTSYSSTQ---PTSYDQSSYSQQNTYGQPSSYGQ-Q 229
Query: 124 GSYDEQSNYDQQHD--------SYSQNQQSYHSQRENYSHHT---QDDRRDVSRYGEDNR 172
SY +QS+Y QQ SYSQ Y Q +Y + QD + YG+++
Sbjct: 230 SSYGQQSSYGQQPPTSYPPQTGSYSQAPSQYSQQSSSYGQQSSFRQDHPSSMGVYGQESG 289
Query: 173 GYGG-----SQGG----GRGRGGYDKDG--RGPMTGSSGG----DRGGFKNFGGHRDYGP 217
G+ G S G GRGRGG+D+ G RG G GG +RGGF GG D GP
Sbjct: 290 GFSGPGENRSMSGPDNRGRGRGGFDRGGMSRGGRGGGRGGMGAGERGGFNKPGGPMDEGP 349
Query: 218 RTDADSESD---NSDNNTIFVQGLGEGVSTDQVGEFFKQIGIIKTNKKTGKPMINLYTDK 274
D D +SDN+ I+VQGL + V+ D + +FFKQ G++K NK+TG+PMI++Y DK
Sbjct: 350 DLDLGPPVDPDEDSDNSAIYVQGLNDSVTLDDLADFFKQCGVVKMNKRTGQPMIHIYLDK 409
Query: 275 DTGKPKGEATVSFDDPPSAKAAIDWFDGKEFHGNIIKVSFATRRPEF--MRGG------- 325
+TGKPKG+ATVS++DPP+AKAA++WFDGK+F G+ +KVS A ++P MRGG
Sbjct: 410 ETGKPKGDATVSYEDPPTAKAAVEWFDGKDFQGSKLKVSLARKKPPMNSMRGGLPPREGR 469
Query: 326 -------------GSGGGRRGRGGYRG--RGGFQGRG-----GDP--------KSGDWVC 357
G GG GR G RG RGGF RG G+P ++GDW C
Sbjct: 470 GMPPPLRGGPGGPGGPGGPMGRMGGRGGDRGGFPPRGPRGSRGNPSGGGNVQHRAGDWQC 529
Query: 358 PNPSCGNMNFARRNSCNQCNEPRPEDSRPSGGDFRGRGYGGERGYRGRGGRGGDRGGYGG 417
PNP CGN NFA R CNQC P+PE P + G RGRGG GG RGG GG
Sbjct: 530 PNPGCGNQNFAWRTECNQCKAPKPEGFLPP-------PFPPPGGDRGRGGPGGMRGGRGG 582
Query: 418 DRSGGGYGGDRSSGGGYSGDRSG--GGYGGDRSGGGYGGDRGGGYGGDRG------GGYG 469
GG GG GG GDR G GG G DR GG+GG R GG GG G GG
Sbjct: 583 LMDRGGPGG--MFRGGRGGDRGGFRGGRGMDR--GGFGGGRRGGPGGPPGPLMEQMGGRR 638
Query: 470 GDRGGGYGGDRGGYGGDR 487
G RGG D+G + +R
Sbjct: 639 GGRGGPGKMDKGEHRQER 656
Score = 117 bits (294), Expect = 2e-26
Identities = 190/705 (26%), Positives = 253/705 (35%), Gaps = 164/705 (23%)
Query: 2 SDSGSYGQSGGEQQSYSTYGNPGSQGYGQASQ-----SYSGYGQTTDSSYGQNYSGYSSY 56
+D +Y Q+ QQ YS Y +QGY Q +Q SY YGQ TD SY Q + ++Y
Sbjct: 4 TDYSTYSQAAA-QQGYSAYTAQPTQGYAQTTQAYGQQSYGTYGQPTDVSYTQAQTT-ATY 61
Query: 57 GQS-YSQSYGGYENQKQSSYSQQPYNNQGQQQNMESSGSQGGRAP-SYDQPDYGQ-QDSY 113
GQ+ Y+ SYG QP +G S+G AP +Y QP G +Y
Sbjct: 62 GQTAYATSYG------------QPPTVEGT-----STGYTTPTAPQAYSQPVQGYGTGAY 104
Query: 114 DQQSG-YDQHQGSYDEQSNYDQQ--HDSYSQNQQSYHSQRE---NYSHHTQDDRRDVSRY 167
D + Q SY QS Y Q + +Y Q + R N T + Y
Sbjct: 105 DTTTATVTTTQASYAAQSAYGTQPAYPAYGQQPAATAPTRPQDGNKPTETSQPQSSTGGY 164
Query: 168 GEDNRGYGGSQGG-GRGRGGYDKDGRGPMTGSSGGDRGGFKNFGGHRDYGPRTDADSESD 226
+ + GYG S + G Y P+T Y P + + ++
Sbjct: 165 NQPSLGYGQSNYSYPQVPGSYPMQ---PVTAPPS--------------YPPTSYSSTQPT 207
Query: 227 NSDNNTIFVQGL-GEGVSTDQVGEFFKQIGIIKTNKKTGKPMINLYTDKDT-----GKPK 280
+ D ++ Q G+ S Q + +Q + + P Y+ +
Sbjct: 208 SYDQSSYSQQNTYGQPSSYGQQSSYGQQSSYGQQPPTSYPPQTGSYSQAPSQYSQQSSSY 267
Query: 281 GEATVSFDDPPSAKAAIDWFDGKEFHGNIIKVSFA------TRRPEFMRGG----GSGGG 330
G+ + D PS+ G F G S + R F RGG G GGG
Sbjct: 268 GQQSSFRQDHPSSMGVYGQESGG-FSGPGENRSMSGPDNRGRGRGGFDRGGMSRGGRGGG 326
Query: 331 RRG-----RGGYRGRGGFQGRGGDPKSGDWVCPNPS------------------------ 361
R G RGG+ GG G D G V P+
Sbjct: 327 RGGMGAGERGGFNKPGGPMDEGPDLDLGPPVDPDEDSDNSAIYVQGLNDSVTLDDLADFF 386
Query: 362 --CGNMNFARRNSCNQCNEPRPEDSRPSGGD-----------------FRGRGYGGER-- 400
CG + +R + +++ GD F G+ + G +
Sbjct: 387 KQCGVVKMNKRTGQPMIHIYLDKETGKPKGDATVSYEDPPTAKAAVEWFDGKDFQGSKLK 446
Query: 401 ---------------GYRGRGGRGGDRGGYGGDRSGGGYGGDRSSGGGYSGDRSGGGYGG 445
G R GRG GG GG GG GG GDR G G
Sbjct: 447 VSLARKKPPMNSMRGGLPPREGRGMPPPLRGGPGGPGGPGGPMGRMGGRGGDRGGFPPRG 506
Query: 446 DRSGGGYGGDRGGGYGGDRGGGYGGDRGGGYGGDRGGYGGDRGGGYGGDRGGY------- 498
R G G GGG R G + G G + + G+
Sbjct: 507 PR--GSRGNPSGGGNVQHRAGDWQCPNPG-CGNQNFAWRTECNQCKAPKPEGFLPPPFPP 563
Query: 499 -GGDRGGYGGDRGGYGGDRGGYGGDRSRGGYGG-DRGGGSGYGGDRSGGYGGDRSGGGYG 556
GGDRG RGG GG RGG GG RGG GG RGG G G GG G DR GG+G
Sbjct: 564 PGGDRG-----RGGPGGMRGGRGGLMDRGGPGGMFRGGRGGDRGGFRGGRGMDR--GGFG 616
Query: 557 GDRGGGYGGDRG----GYGGKMGGR--------NDYRNDQRNRPY 589
G R GG GG G GG+ GGR ++R ++R+RPY
Sbjct: 617 GGRRGGPGGPPGPLMEQMGGRRGGRGGPGKMDKGEHRQERRDRPY 661
>gi|55956899 keratin 9 [Homo sapiens]
Length = 623
Score = 157 bits (396), Expect = 3e-38
Identities = 90/171 (52%), Positives = 95/171 (55%), Gaps = 15/171 (8%)
Query: 397 GGERGYRGRGGRGGDRGGYGGDRSGGGYGGDRSSGGGYSGDRSGGGYGGDRSGGGYGGDR 456
GG+ + G GG GG SGG YG R S GG SGG YGG SGGGYGG
Sbjct: 460 GGQEDFESSGAGKIGLGGRGG--SGGSYG--RGSRGG-----SGGSYGGGGSGGGYGG-- 508
Query: 457 GGGYGGDRGGGYGGDRGGGYGGDRGGYGGDRGGGYGGDRGG--YGGDRGGYGGDRGGYGG 514
G G G GG YGG G G GG GGYGG GGG+ G GG GG G YGG G GG
Sbjct: 509 GSGSRGGSGGSYGGGSGSG-GGSGGGYGGGSGGGHSGGSGGGHSGGSGGNYGGGSGSGGG 567
Query: 515 DRGGY-GGDRSRGGYGGDRGGGSGYGGDRSGGYGGDRSGGGYGGDRGGGYG 564
GGY GG SRGG GG GGGSG+GG+ G YGG G GG GGG G
Sbjct: 568 SGGGYGGGSGSRGGSGGSHGGGSGFGGESGGSYGGGEEASGSGGGYGGGSG 618
Score = 157 bits (396), Expect = 3e-38
Identities = 84/158 (53%), Positives = 89/158 (56%), Gaps = 4/158 (2%)
Query: 382 EDSRPSGGDFRGRG-YGGERGYRGRGGRGGDRGGYGGDRSGGGYGGDRSSGGGYSGDRSG 440
ED SG G G GG G GRG RGG G YGG SGGGYGG S GG G G
Sbjct: 463 EDFESSGAGKIGLGGRGGSGGSYGRGSRGGSGGSYGGGGSGGGYGGGSGSRGGSGGSYGG 522
Query: 441 GGYGGDRSGGGYGGDRGGGYGGDRGGGYGGDRGGGYGGDRGGYGGDRGGGYGGDRGGYGG 500
G G SGGGYGG GGG+ G GGG+ G GG YGG G GG GGGYGG G GG
Sbjct: 523 GSGSGGGSGGGYGGGSGGGHSGGSGGGHSGGSGGNYGGGSGS-GGGSGGGYGGGSGSRGG 581
Query: 501 DRGGYGGDRGGYGGDRGG-YGGDRSRGGYGGDRGGGSG 537
G +GG G+GG+ GG YGG G GG GGGSG
Sbjct: 582 SGGSHGGG-SGFGGESGGSYGGGEEASGSGGGYGGGSG 618
Score = 106 bits (264), Expect = 7e-23
Identities = 69/144 (47%), Positives = 75/144 (52%), Gaps = 19/144 (13%)
Query: 403 RGRGGRGGDRGGYGGDRSGGGYGGDRSSGGGYSGDR--SGGGYGGDRS---GGGYGGDRG 457
R GG GG G G RS Y SSGGG G R S GYGG S G G GG G
Sbjct: 13 RSGGGGGGGLGSGGSIRSS--YSRFSSSGGGGGGGRFSSSSGYGGGSSRVCGRGGGGSFG 70
Query: 458 GGYGGDRGGGYGGDR-GGGYGGDRGGYGGDRGGGY---GGDRGGYGGDRGGYGGDRGGYG 513
YGG GGG+ GGG+GG G+GG GGGY GG GG+GG G GG GGYG
Sbjct: 71 YSYGGGSGGGFSASSLGGGFGGGSRGFGGASGGGYSSSGGFGGGFGGGSG--GGFGGGYG 128
Query: 514 GDRGGYGGDRSRGGYGGDRGGGSG 537
GG+ GG+GG GGG G
Sbjct: 129 SGFGGF------GGFGGGAGGGDG 146
Score = 105 bits (263), Expect = 9e-23
Identities = 70/142 (49%), Positives = 73/142 (51%), Gaps = 20/142 (14%)
Query: 450 GGYGGDRGGGYGGDRGGGYGGDRGGGYG-GDRGGYGGDRGGGYGGDRGGYGGDRGGYGGD 508
GG G G GG GG GG YG G RGG GG GGG G GGYGG G GG
Sbjct: 460 GGQEDFESSGAGKIGLGGRGGS-GGSYGRGSRGGSGGSYGGG--GSGGGYGGGSGSRGGS 516
Query: 509 RGGYGGDRGGYGGDRSRGGYGGDRGGGS------GYGGDRSGGYGGDRSGG-GYGGDRGG 561
G YGG G S GG GG GGGS G GG SGG GG+ GG G GG GG
Sbjct: 517 GGSYGGGSG------SGGGSGGGYGGGSGGGHSGGSGGGHSGGSGGNYGGGSGSGGGSGG 570
Query: 562 GYG---GDRGGYGGKMGGRNDY 580
GYG G RGG GG GG + +
Sbjct: 571 GYGGGSGSRGGSGGSHGGGSGF 592
Score = 103 bits (256), Expect = 6e-22
Identities = 62/137 (45%), Positives = 67/137 (48%), Gaps = 9/137 (6%)
Query: 419 RSGGGYGGDRSSGGGYSGD-----RSGGGYGGDR--SGGGYGGDRGGGYGGDRGGGYGGD 471
RSGGG GG SGG SGGG GG R S GYGG G GG +G
Sbjct: 13 RSGGGGGGGLGSGGSIRSSYSRFSSSGGGGGGGRFSSSSGYGGGSSRVCGRGGGGSFGYS 72
Query: 472 RGGGYGGDRGGYGGDRGGGYGGDRGGYGGDRGGYGGDRGGYGGDRGGYGGDRSRGGYGGD 531
GGG GG G GGG+GG G+GG GG GG+GG GG G GGYG
Sbjct: 73 YGGGSGG--GFSASSLGGGFGGGSRGFGGASGGGYSSSGGFGGGFGGGSGGGFGGGYGSG 130
Query: 532 RGGGSGYGGDRSGGYGG 548
GG G+GG GG GG
Sbjct: 131 FGGFGGFGGGAGGGDGG 147
Score = 100 bits (250), Expect = 3e-21
Identities = 65/140 (46%), Positives = 70/140 (50%), Gaps = 9/140 (6%)
Query: 384 SRPSGGDFRGRGYGGE-RGYRGRGGRGGDRGGYGGDRSGGGYGGDRSSGGGYSGDRSGG- 441
SR GG G G GG R R G GG G S GYGG S G G S G
Sbjct: 12 SRSGGGGGGGLGSGGSIRSSYSRFSSSGGGGGGGRFSSSSGYGGGSSRVCGRGGGGSFGY 71
Query: 442 GYGGDRSGGGYGGDRGGGYGGDRGGGYGGDRGGGY---GGDRGGYGGDRGGGYGGDRGGY 498
YGG GG GGG+GG G+GG GGGY GG GG+GG GGG+G GGY
Sbjct: 72 SYGGGSGGGFSASSLGGGFGGG-SRGFGGASGGGYSSSGGFGGGFGGGSGGGFG---GGY 127
Query: 499 GGDRGGYGGDRGGYGGDRGG 518
G GG+GG GG GG GG
Sbjct: 128 GSGFGGFGGFGGGAGGGDGG 147
Score = 95.1 bits (235), Expect = 2e-19
Identities = 69/173 (39%), Positives = 72/173 (41%), Gaps = 53/173 (30%)
Query: 324 GGGSGGGRRGRGGYRGRGGFQGRGGDPKSGDWVCPNPSCGNMNFARRNSCNQCNEPRPED 383
GGGSGGG G G RG G GG G
Sbjct: 499 GGGSGGGYGGGSGSRGGSGGSYGGGSGSGGG----------------------------- 529
Query: 384 SRPSGGDFRGRGYGGERGYRGRGGRGGDRGGYGGDRSGGGYGGDRSSGGGYSGDRSGGGY 443
SGG GYGG G GG G GG SGG YGG SGGG SGGGY
Sbjct: 530 ---SGG-----GYGGGSG----GGHSGGSGGGHSGGSGGNYGGGSGSGGG-----SGGGY 572
Query: 444 GGDRSGGGYGGDRGGGYGGDRGGGYGGDRGGGYGGDRGGYGGDRGGGYGGDRG 496
GG G G G GG +GG G G+GG+ GG YGG G GGGYGG G
Sbjct: 573 GG---GSGSRGGSGGSHGG--GSGFGGESGGSYGGGEEASGS--GGGYGGGSG 618
Score = 89.7 bits (221), Expect = 7e-18
Identities = 67/175 (38%), Positives = 75/175 (42%), Gaps = 44/175 (25%)
Query: 323 RGGGSGGGRRGRGG--YRGRGGFQGRGGDPKSGDWVCPNPSCGNMNFARRNSCNQCNEPR 380
R GG GGG G GG F GG G +
Sbjct: 13 RSGGGGGGGLGSGGSIRSSYSRFSSSGGGGGGGRF------------------------- 47
Query: 381 PEDSRPSGGDFR--GRGYGGERGYRGRGGRGGDRGGYGGDRSGGGYGGDRSSGGGYSGDR 438
S GG R GRG GG GY GG G GG+ GGG+GG GG
Sbjct: 48 SSSSGYGGGSSRVCGRGGGGSFGYSYGGGSG---GGFSASSLGGGFGGGSRGFGG----A 100
Query: 439 SGGGYGGDRSGGGYGGDRGGGYGGDRGGGYGGDRGGGYGGDRGGYGGDRGGGYGG 493
SGGGY S GG+ GGG+GG GGG+GG G G+GG GG+GG GGG GG
Sbjct: 101 SGGGYS---SSGGF----GGGFGGGSGGGFGGGYGSGFGG-FGGFGGGAGGGDGG 147
Score = 89.0 bits (219), Expect = 1e-17
Identities = 61/137 (44%), Positives = 68/137 (49%), Gaps = 13/137 (9%)
Query: 447 RSGGGYGGDRGGGYGGDRGGGYG--GDRGGGYGGDRGGYGGDRGGGYGGDRGGYGGDRGG 504
RSGGG GG G G GG Y GGG GG R GGG G GG G
Sbjct: 13 RSGGGGGG--GLGSGGSIRSSYSRFSSSGGGGGGGRFSSSSGYGGGSSRVCGRGGGGSFG 70
Query: 505 Y---GGDRGGYGGDR--GGYGGDRSRGGYGGDRGGGSGYGGDRSGGYGGDRSGGGYGGDR 559
Y GG GG+ GG+GG G+GG GGG G GG+GG SGGG+GG
Sbjct: 71 YSYGGGSGGGFSASSLGGGFGG--GSRGFGGASGGGYSSSGGFGGGFGGG-SGGGFGGGY 127
Query: 560 GGGYGGDRGGYGGKMGG 576
G G+GG GG+GG GG
Sbjct: 128 GSGFGG-FGGFGGGAGG 143
Score = 41.6 bits (96), Expect = 0.002
Identities = 44/144 (30%), Positives = 55/144 (38%), Gaps = 11/144 (7%)
Query: 78 QPYNN--QGQQQNMESSGSQ----GGRAPSYDQPDYGQQDSYDQQSGYDQHQGSYDEQS- 130
+ Y+N +G Q++ ESSG+ GGR S G + G G Y S
Sbjct: 452 ETYHNLLEGGQEDFESSGAGKIGLGGRGGSGGSYGRGSRGGSGGSYGGGGSGGGYGGGSG 511
Query: 131 NYDQQHDSYSQNQQSYHSQRENYSHHTQDDRRDVSRYGEDNRGYGGSQGGGRGRGGYDKD 190
+ SY S Y + S G G GG+ GGG G GG
Sbjct: 512 SRGGSGGSYGGGSGSGGGSGGGYGGGSGGGHSGGSGGGHSG-GSGGNYGGGSGSGGGSGG 570
Query: 191 GRGPMTGS---SGGDRGGFKNFGG 211
G G +GS SGG GG FGG
Sbjct: 571 GYGGGSGSRGGSGGSHGGGSGFGG 594
Score = 39.3 bits (90), Expect = 0.010
Identities = 32/108 (29%), Positives = 42/108 (38%), Gaps = 10/108 (9%)
Query: 5 GSYGQSGGEQQSYSTYGNPGSQGYGQASQSYSGYGQTTD--------SSYGQNYSGYSSY 56
G G G + SYS + + G G G S SGYG + S+G +Y G S
Sbjct: 20 GGLGSGGSIRSSYSRFSSSGGGGGGGRFSSSSGYGGGSSRVCGRGGGGSFGYSYGGGSGG 79
Query: 57 GQSYSQSYGGYENQKQ--SSYSQQPYNNQGQQQNMESSGSQGGRAPSY 102
G S S GG+ + S Y++ G GS GG Y
Sbjct: 80 GFSASSLGGGFGGGSRGFGGASGGGYSSSGGFGGGFGGGSGGGFGGGY 127
Score = 37.7 bits (86), Expect = 0.030
Identities = 26/57 (45%), Positives = 27/57 (47%), Gaps = 6/57 (10%)
Query: 524 SRGGYGGDRGGGSGYGGDRSGGYGG-DRSGGGYGGDR---GGGYGGDRGGYGGKMGG 576
SR G GG GGG G GG Y SGGG GG R GYGG G+ GG
Sbjct: 12 SRSGGGG--GGGLGSGGSIRSSYSRFSSSGGGGGGGRFSSSSGYGGGSSRVCGRGGG 66
Score = 37.4 bits (85), Expect = 0.039
Identities = 30/98 (30%), Positives = 36/98 (36%), Gaps = 1/98 (1%)
Query: 5 GSYGQSGGEQQSYSTYGNPGSQGYGQASQSYSGYGQTTDSSYGQNYSGYSSYGQSYSQSY 64
G G SGG S G+ GS G G + Y G G + G +Y G S G Y
Sbjct: 476 GGRGGSGGSYGRGSRGGSGGSYGGGGSGGGYGG-GSGSRGGSGGSYGGGSGSGGGSGGGY 534
Query: 65 GGYENQKQSSYSQQPYNNQGQQQNMESSGSQGGRAPSY 102
GG S S ++ SGS GG Y
Sbjct: 535 GGGSGGGHSGGSGGGHSGGSGGNYGGGSGSGGGSGGGY 572
Score = 37.0 bits (84), Expect = 0.051
Identities = 19/50 (38%), Positives = 24/50 (48%), Gaps = 5/50 (10%)
Query: 167 YGEDNRGYGGSQGGGRGR-----GGYDKDGRGPMTGSSGGDRGGFKNFGG 211
+G +RG+GG+ GGG GG+ G G G GGF FGG
Sbjct: 90 FGGGSRGFGGASGGGYSSSGGFGGGFGGGSGGGFGGGYGSGFGGFGGFGG 139
Score = 36.2 bits (82), Expect = 0.087
Identities = 25/50 (50%), Positives = 26/50 (52%), Gaps = 8/50 (16%)
Query: 536 SGYGGDRSGGYGGDRSGGGYG----GDRGGGYGGDRGGYGGKMGGRNDYR 581
SG G GG GG SGG YG G GG YGG GG GG GG + R
Sbjct: 468 SGAGKIGLGGRGG--SGGSYGRGSRGGSGGSYGG--GGSGGGYGGGSGSR 513
Score = 34.3 bits (77), Expect = 0.33
Identities = 53/208 (25%), Positives = 63/208 (30%), Gaps = 52/208 (25%)
Query: 12 GEQQSYSTYGNPGSQGYGQASQSYSGYGQTTDSSYGQNYSGYSSYGQSYSQSYGGYENQK 71
G Q+ + + G G G G S YG+ + G +Y G S G YGG
Sbjct: 460 GGQEDFESSG-AGKIGLGGRGGSGGSYGRGSRGGSGGSYGGGGSGG-----GYGG----- 508
Query: 72 QSSYSQQPYNNQGQQQNMESSGSQGGRAPSYDQPDYGQQDSYDQQSGYDQHQGSYDEQSN 131
SGS+GG SY G GY G
Sbjct: 509 -------------------GSGSRGGSGGSYGG---GSGSGGGSGGGYGGGSGG------ 540
Query: 132 YDQQHDSYSQNQQSYHSQRE--NYSHHTQDDRRDVSRYGEDNR---GYGGSQGGGRGRGG 186
+S HS NY + YG + G GGS GGG G GG
Sbjct: 541 ------GHSGGSGGGHSGGSGGNYGGGSGSGGGSGGGYGGGSGSRGGSGGSHGGGSGFGG 594
Query: 187 YD--KDGRGPMTGSSGGDRGGFKNFGGH 212
G G SGG GG H
Sbjct: 595 ESGGSYGGGEEASGSGGGYGGGSGKSSH 622
Score = 34.3 bits (77), Expect = 0.33
Identities = 21/52 (40%), Positives = 23/52 (44%), Gaps = 6/52 (11%)
Query: 168 GEDNRGYGGSQGGGR--GRGGYDKDGRGPM----TGSSGGDRGGFKNFGGHR 213
G GYGG GGG G GG G G +GS GG GG+ G R
Sbjct: 528 GGSGGGYGGGSGGGHSGGSGGGHSGGSGGNYGGGSGSGGGSGGGYGGGSGSR 579
Score = 33.9 bits (76), Expect = 0.43
Identities = 31/94 (32%), Positives = 41/94 (43%), Gaps = 5/94 (5%)
Query: 4 SGSYGQSGGEQQSYSTYGNPGSQGYGQASQSYSGYGQTTDSSYGQNYSGYSSYGQSYSQS 63
SGS G SGG S G+ G G G + S YG + S G SG G S S+
Sbjct: 524 SGSGGGSGGGYGGGSGGGHSGGSGGGHSGGSGGNYGGGSGSGGG---SGGGYGGGSGSRG 580
Query: 64 YGGYENQKQSSYSQQPYNNQGQQQNMESSGSQGG 97
G + S + + + G + E+SGS GG
Sbjct: 581 GSGGSHGGGSGFGGESGGSYGGGE--EASGSGGG 612
Score = 33.5 bits (75), Expect = 0.56
Identities = 42/187 (22%), Positives = 66/187 (35%), Gaps = 32/187 (17%)
Query: 56 YGQSYSQSYGGYENQKQSSYSQQPYNNQGQQQNMESSG------------------SQGG 97
Y Q +++ ENQ ++ +Q + Q ++SS SQ
Sbjct: 330 YEQLIAKNRKDIENQYETQITQIEHEVSSSGQEVQSSAKEVTQLRHGVQELEIELQSQLS 389
Query: 98 RAPSYDQPDYGQQDSYDQQSGYDQHQGSYDEQSNYDQQHDSYSQNQQ---------SYHS 148
+ + ++ ++ Y Q Q Q S E D + + QNQ+
Sbjct: 390 KKAALEKSLEDTKNRYCGQLQMIQEQISNLEAQITDVRQEIECQNQEYSLLLSIKMRLEK 449
Query: 149 QRENYSHHTQDDRRDVSRYGEDNRGYGGSQGGGRGRGGYDKDGRGPMTGS--SGGDRGGF 206
+ E Y + + + D G G GG G G G Y + RG GS GG GG+
Sbjct: 450 EIETYHNLLEGGQEDFESSGAGKIGLGGRGGSG---GSYGRGSRGGSGGSYGGGGSGGGY 506
Query: 207 KNFGGHR 213
G R
Sbjct: 507 GGGSGSR 513
Score = 32.7 bits (73), Expect = 0.96
Identities = 22/67 (32%), Positives = 32/67 (47%), Gaps = 9/67 (13%)
Query: 6 SYGQSGGEQQSYSTYGNP---GSQGYGQASQSYSGYGQTTDSSYGQNYSGYSS--YGQSY 60
SYG G S S+ G GS+G+G AS G G ++ +G + G S +G Y
Sbjct: 72 SYGGGSGGGFSASSLGGGFGGGSRGFGGAS----GGGYSSSGGFGGGFGGGSGGGFGGGY 127
Query: 61 SQSYGGY 67
+GG+
Sbjct: 128 GSGFGGF 134
Score = 32.7 bits (73), Expect = 0.96
Identities = 19/45 (42%), Positives = 22/45 (48%), Gaps = 1/45 (2%)
Query: 173 GYGGSQGGGRGRGGYDKDGRGPMTGSS-GGDRGGFKNFGGHRDYG 216
G GGS GGG G GG G G +G G GG + G +YG
Sbjct: 515 GSGGSYGGGSGSGGGSGGGYGGGSGGGHSGGSGGGHSGGSGGNYG 559
Score = 32.3 bits (72), Expect = 1.3
Identities = 24/68 (35%), Positives = 27/68 (39%), Gaps = 2/68 (2%)
Query: 2 SDSGSYGQSGGEQQSYSTYGNPGSQGYGQASQSYSGYGQT--TDSSYGQNYSGYSSYGQS 59
S G G SGG S G GYG S S G G + S +G G G+
Sbjct: 546 SGGGHSGGSGGNYGGGSGSGGGSGGGYGGGSGSRGGSGGSHGGGSGFGGESGGSYGGGEE 605
Query: 60 YSQSYGGY 67
S S GGY
Sbjct: 606 ASGSGGGY 613
Score = 31.6 bits (70), Expect = 2.1
Identities = 24/65 (36%), Positives = 28/65 (43%), Gaps = 1/65 (1%)
Query: 168 GEDNRGYGGSQGGGRGRGGYDKDGRGPMTGSSGGDRGGFKNFGGHRDYGPRTDADSESDN 227
G GY S G G G GG G G GS G GGF G D G T A+ +S
Sbjct: 99 GASGGGYSSSGGFGGGFGGGSGGGFGGGYGSGFGGFGGFGGGAGGGDGGILT-ANEKSTM 157
Query: 228 SDNNT 232
+ N+
Sbjct: 158 QELNS 162
Score = 31.2 bits (69), Expect = 2.8
Identities = 37/127 (29%), Positives = 41/127 (32%), Gaps = 22/127 (17%)
Query: 4 SGSYGQSGGEQQSYSTYGNPGSQ------GYGQASQS--YSGYGQTTDSSYGQNYSGYSS 55
SGS G SGG +YG GYG S G G G NY G S
Sbjct: 510 SGSRGGSGG------SYGGGSGSGGGSGGGYGGGSGGGHSGGSGGGHSGGSGGNYGGGSG 563
Query: 56 YGQSYSQSYGGYENQKQSSYSQQPYNNQGQQQNMESSGSQGGRAPSYDQPDYGQQDSYDQ 115
G YGG + S + G ES GS GG + G Y
Sbjct: 564 SGGGSGGGYGGGSGSRGGSGGS---HGGGSGFGGESGGSYGG-----GEEASGSGGGYGG 615
Query: 116 QSGYDQH 122
SG H
Sbjct: 616 GSGKSSH 622
Score = 29.6 bits (65), Expect = 8.1
Identities = 16/42 (38%), Positives = 18/42 (42%), Gaps = 2/42 (4%)
Query: 175 GGSQGGGRGRGGYDKDGRGPMTGSSGGDRGGFKNFGGHRDYG 216
GG GGG G GG + + S GG GG F YG
Sbjct: 15 GGGGGGGLGSGGSIRSSYSRFSSSGGGGGGG--RFSSSSGYG 54
>gi|14043070 heterogeneous nuclear ribonucleoprotein A1 isoform b
[Homo sapiens]
Length = 372
Score = 147 bits (371), Expect = 3e-35
Identities = 121/346 (34%), Positives = 153/346 (44%), Gaps = 71/346 (20%)
Query: 218 RTDADSESDNSDNNTIFVQGLGEGVSTDQVGEFFKQIGIIKTNKKTGKPMINLYTDKDTG 277
R D+ + IFV G+ E + ++F+Q G I+ +I + TD+ +G
Sbjct: 92 REDSQRPGAHLTVKKIFVGGIKEDTEEHHLRDYFEQYGKIE--------VIEIMTDRGSG 143
Query: 278 KPKGEATVSFDDPPSAKAAIDWFDGKEFH---GNIIKVSFATRRPEFMRGGGSGGGRRGR 334
K +G A V+FDD S +D +++H G+ +V A + E S GR G
Sbjct: 144 KKRGFAFVTFDDHDS----VDKIVIQKYHTVNGHNCEVRKALSKQEMASASSSQRGRSGS 199
Query: 335 GGYRGRGGFQGRGGDPKSGDWVCPNPSCGNMNFARRNSCNQCNEPRPEDSRPSGGDFRGR 394
G + G GRGG GN NF R GG+F GR
Sbjct: 200 GNFGG-----GRGGG-----------FGGNDNFGR------------------GGNFSGR 225
Query: 395 GYGGERGYRGRGGRGGDRGGYGGDRSGGGYGGDRSSGGGYSGDRSGGGYGGDRSGGGYGG 454
GG G RG GG GG GY G + GGYGG G GYSG G G GG GY G
Sbjct: 226 --GGFGGSRGGGGYGGSGDGYNGFGNDGGYGG---GGPGYSGGSRGYGSGGQ----GY-G 275
Query: 455 DRGGGYGGDRGGGYGGDRGGGYGGDRGGYGGDRGGGYGGDRGGYGGDRGGYGGDRGGYGG 514
++G GYGG G Y GG GG+GG G +GG GG D G Y +G
Sbjct: 276 NQGSGYGG--SGSYDSYNNGG----GGGFGGGSGSNFGG--GGSYNDFGNYNNQSSNFGP 327
Query: 515 DRGGYGGDRSRGGYGGDRGGGSGYGGDRS-GGYGGDRSGGGYGGDR 559
+GG G RS G YG GGG + R+ GGYGG S YG R
Sbjct: 328 MKGGNFGGRSSGPYG---GGGQYFAKPRNQGGYGGSSSSSSYGSGR 370
Score = 124 bits (311), Expect = 2e-28
Identities = 81/178 (45%), Positives = 93/178 (52%), Gaps = 15/178 (8%)
Query: 399 ERGYRGRGGRGGDRGGYGGDRSGGGYGGDRSSGGGYSGDRSGGGYGGDRSGGGYGG-DRG 457
+RG G G GG RGG G G GG+ S GG+ G R GGGYGG SG GY G
Sbjct: 193 QRGRSGSGNFGGGRGGGFGGNDNFGRGGNFSGRGGFGGSRGGGGYGG--SGDGYNGFGND 250
Query: 458 GGYGGDRGGGYGGDRGGGYGGDRGGYGGDRGGGYGGDRGGYGGDRGGYGGDRGGYGGDRG 517
GGYGG G GG RG G GG GY G++G GYGG G Y G GG G GG
Sbjct: 251 GGYGGGGPGYSGGSRGYGSGGQ--GY-GNQGSGYGGS-GSYDSYNNGGGGGFG--GGSGS 304
Query: 518 GYGGDRSRGGYGGDRGGGSGYGGDRSGGYGGDRSGGGYGGDRGGGYGG---DRGGYGG 572
+GG S +G S +G + G +GG RS G YGG GG Y ++GGYGG
Sbjct: 305 NFGGGGSYNDFGNYNNQSSNFGPMKGGNFGG-RSSGPYGG--GGQYFAKPRNQGGYGG 359
Score = 107 bits (267), Expect = 3e-23
Identities = 69/139 (49%), Positives = 79/139 (56%), Gaps = 20/139 (14%)
Query: 447 RSGGG-YGGDRGGGYGGDRGGGYGGDRGGGYGGDRGGYGGDRGGG-YGGDRGGYGGDRGG 504
RSG G +GG RGGG+GG+ G RGG + G RGG+GG RGGG YGG GY G
Sbjct: 196 RSGSGNFGGGRGGGFGGNDNFG----RGGNFSG-RGGFGGSRGGGGYGGSGDGYNG---- 246
Query: 505 YGGDRGGYGGDRGGY-GGDRSRGGYGGDRGGGSGYGGDRSGGYGGDRSGGGYGGDRGGGY 563
+G D GGYGG GY GG R GYG GG GY G++ GYGG S Y GGG+
Sbjct: 247 FGND-GGYGGGGPGYSGGSR---GYG---SGGQGY-GNQGSGYGGSGSYDSYNNGGGGGF 298
Query: 564 GGDRGGYGGKMGGRNDYRN 582
GG G G G ND+ N
Sbjct: 299 GGGSGSNFGGGGSYNDFGN 317
Score = 55.5 bits (132), Expect = 1e-07
Identities = 31/64 (48%), Positives = 38/64 (59%), Gaps = 9/64 (14%)
Query: 521 GDRSRGGYGGDRGGGSGYGGDRSGGYGGDRSG-GGYGGDRGGGYGGDRGGYGGKMGGRND 579
G G +GG RGGG +GG+ + G GG+ SG GG+GG RGGG GYGG G N
Sbjct: 195 GRSGSGNFGGGRGGG--FGGNDNFGRGGNFSGRGGFGGSRGGG------GYGGSGDGYNG 246
Query: 580 YRND 583
+ ND
Sbjct: 247 FGND 250
Score = 50.4 bits (119), Expect = 4e-06
Identities = 38/115 (33%), Positives = 50/115 (43%), Gaps = 10/115 (8%)
Query: 6 SYGQSGGEQQSYSTYGNPGSQGYGQASQSYSGYGQTTDSSYGQNYSGYSSYGQSYSQSYG 65
++G+ G G+ G GYG + Y+G+G D YG GYS + Y
Sbjct: 215 NFGRGGNFSGRGGFGGSRGGGGYGGSGDGYNGFGN--DGGYGGGGPGYSGGSRGYGSGGQ 272
Query: 66 GYENQKQS---SYSQQPYNNQGQQQNMESSGSQGGRAPSYDQPDYGQQDSYDQQS 117
GY NQ S S YNN G SGS G SY+ D+G +Y+ QS
Sbjct: 273 GYGNQGSGYGGSGSYDSYNNGGGGGFGGGSGSNFGGGGSYN--DFG---NYNNQS 322
Score = 44.7 bits (104), Expect = 2e-04
Identities = 37/152 (24%), Positives = 55/152 (36%), Gaps = 14/152 (9%)
Query: 68 ENQKQSSYSQQPYNNQGQQQNMESSGSQGGRAPSYDQPD-YGQQDSYDQQSGYDQHQGSY 126
E +K S + + Q+ S GGR + D +G+ ++ + G+ +G
Sbjct: 176 EVRKALSKQEMASASSSQRGRSGSGNFGGGRGGGFGGNDNFGRGGNFSGRGGFGGSRGG- 234
Query: 127 DEQSNYDQQHDSYSQ--NQQSYHSQRENYSHHTQDDRRDVSRYGEDNRGYGGSQGGGRGR 184
Y D Y+ N Y YS ++ YG +GYG G G
Sbjct: 235 ---GGYGGSGDGYNGFGNDGGYGGGGPGYSGGSRG-------YGSGGQGYGNQGSGYGGS 284
Query: 185 GGYDKDGRGPMTGSSGGDRGGFKNFGGHRDYG 216
G YD G G GG F G + D+G
Sbjct: 285 GSYDSYNNGGGGGFGGGSGSNFGGGGSYNDFG 316
Score = 38.5 bits (88), Expect = 0.017
Identities = 28/76 (36%), Positives = 31/76 (40%), Gaps = 3/76 (3%)
Query: 168 GEDNRGYGGSQGGGRGRGGYDKDGRGPMTGSSGGDRGGFKNFGGHRDYGPRTDADSESDN 227
G DN G GG+ GRGG+ G G SG GF N GG+ GP S
Sbjct: 212 GNDNFGRGGNF---SGRGGFGGSRGGGGYGGSGDGYNGFGNDGGYGGGGPGYSGGSRGYG 268
Query: 228 SDNNTIFVQGLGEGVS 243
S QG G G S
Sbjct: 269 SGGQGYGNQGSGYGGS 284
Score = 38.5 bits (88), Expect = 0.017
Identities = 36/130 (27%), Positives = 47/130 (36%), Gaps = 17/130 (13%)
Query: 3 DSGSYGQSGGEQQSYSTYGNPGSQGYGQASQSYSGYGQTTDSSYGQNYSGYSSYGQSYSQ 62
+ G YG G S G QGYG Y G G S N G +G
Sbjct: 249 NDGGYGGGGPGYSGGSRGYGSGGQGYGNQGSGYGGSG----SYDSYNNGGGGGFGGGSGS 304
Query: 63 SYGGYENQKQSSYSQ-QPYNNQGQQQNMESSGSQGGRAPSYDQPDYGQQDSYDQQSGYDQ 121
++GG SY+ YNNQ G+ GGR+ YG Y + +
Sbjct: 305 NFGG-----GGSYNDFGNYNNQSSNFGPMKGGNFGGRSSG----PYGGGGQYFAK---PR 352
Query: 122 HQGSYDEQSN 131
+QG Y S+
Sbjct: 353 NQGGYGGSSS 362
Score = 38.5 bits (88), Expect = 0.017
Identities = 29/104 (27%), Positives = 41/104 (39%), Gaps = 11/104 (10%)
Query: 5 GSYGQSGGEQQSYSTYGNPGSQGYGQASQSYSGYGQTTDSSYGQNYSGYSSYGQSYSQSY 64
G+ G G SY +Y N G G+G S S G G +Y+ + +Y + S ++
Sbjct: 275 GNQGSGYGGSGSYDSYNNGGGGGFGGGSGSNFG--------GGGSYNDFGNY-NNQSSNF 325
Query: 65 GGYENQKQSSYSQQPYNNQGQQQNMESSGSQGGRAPSYDQPDYG 108
G + S PY GQ +QGG S YG
Sbjct: 326 GPMKGGNFGGRSSGPYGGGGQY--FAKPRNQGGYGGSSSSSSYG 367
Score = 32.3 bits (72), Expect = 1.3
Identities = 21/62 (33%), Positives = 27/62 (43%), Gaps = 2/62 (3%)
Query: 171 NRGYGGSQGGGRGRGGYDKDGR--GPMTGSSGGDRGGFKNFGGHRDYGPRTDADSESDNS 228
+RG GG G G G G+ DG G G SGG RG G+ + G D+
Sbjct: 231 SRGGGGYGGSGDGYNGFGNDGGYGGGGPGYSGGSRGYGSGGQGYGNQGSGYGGSGSYDSY 290
Query: 229 DN 230
+N
Sbjct: 291 NN 292
>gi|34740329 heterogeneous nuclear ribonucleoprotein A3 [Homo
sapiens]
Length = 378
Score = 144 bits (364), Expect = 2e-34
Identities = 122/323 (37%), Positives = 153/323 (47%), Gaps = 78/323 (24%)
Query: 233 IFVQGLGEGVSTDQVGEFFKQIGIIKTNKKTGKPMINLYTDKDTGKPKGEATVSFDDPPS 292
IFV G+ E + ++F++ G I+T I + D+ +GK +G A V+FDD +
Sbjct: 128 IFVGGIKEDTEEYNLRDYFEKYGKIET--------IEVMEDRQSGKKRGFAFVTFDDHDT 179
Query: 293 AKAAIDWFDGKEFH---GNIIKVSFATRRPEFMRGGGSGGGRRGRGGYRGRGGFQGRGGD 349
+D +++H G+ +V A + E S G +RGRGG G G F GRGG
Sbjct: 180 ----VDKIVVQKYHTINGHNCEVKKALSKQEMQ----SAGSQRGRGG--GSGNFMGRGG- 228
Query: 350 PKSGDWVCPNPSCGNMNFARRNSCNQCNEPRPEDSRPSGGDFRGRGYGGERGYRGRGGRG 409
N G NF R GG+F GRG G G RG G
Sbjct: 229 ---------NFGGGGGNFGR------------------GGNFGGRGGYGGGGGGSRGSYG 261
Query: 410 GDRGGYGGDRSGGGYGGDRSSGGGYSGDRSGGGYGGDRSGGGYGGDRGGGYGGDRGGGYG 469
G GGY G+GGD + GG G S GGYGG G GY G++GGGYGG GGGY
Sbjct: 262 GGDGGY------NGFGGDGGNYGGGPGYSSRGGYGG--GGPGY-GNQGGGYGG--GGGYD 310
Query: 470 G-DRGGGYGGDRGGYGGDRGGGYGGDRGGYGGDRGGYGGDRGGYGGDRGGYGGDRSRGG- 527
G + GG +GG G YGG GG Y D G Y G + + YG +GG G RS G
Sbjct: 311 GYNEGGNFGG--GNYGG--GGNY-NDFGNYSGQQ------QSNYGPMKGGSFGGRSSGSP 359
Query: 528 YGGDRGGGSGYGGDRSGGYGGDR 550
YGG G G G SGGYG R
Sbjct: 360 YGGGYGSGGG-----SGGYGSRR 377
Score = 128 bits (322), Expect = 1e-29
Identities = 92/191 (48%), Positives = 101/191 (52%), Gaps = 27/191 (14%)
Query: 387 SGGDFRGRGYGGERGYRGRGGRGGDRGGYGGDRSGGGYGGDRSSGGGYSGDRSGGGYGGD 446
S G RGRG GG + GRGG G GG G GG +GG GGY GGG GG
Sbjct: 209 SAGSQRGRG-GGSGNFMGRGGNFGGGGGNFG--RGGNFGGR----GGY-----GGGGGGS 256
Query: 447 RSGGGYGGDRGG--GYGGDRGGGYGGDRGGGYGGDRGGYGGDRGGGYGGDRGGYGGDRGG 504
R G YGG GG G+GGD G YGG G GY RGGYGG G GYG GGYGG G
Sbjct: 257 R--GSYGGGDGGYNGFGGDG-GNYGG--GPGY-SSRGGYGGG-GPGYGNQGGGYGGGGGY 309
Query: 505 YGGDRGGY--GGDRGGYGGDRSRGGYGGDRGGGSGYGGDRSGGYGGDRSGGGYGGDRGGG 562
G + GG GG+ GG G G Y G + S YG + G +GG SG YGG G G
Sbjct: 310 DGYNEGGNFGGGNYGGGGNYNDFGNYSGQQ--QSNYGPMKGGSFGGRSSGSPYGG--GYG 365
Query: 563 YGGDRGGYGGK 573
GG GGYG +
Sbjct: 366 SGGGSGGYGSR 376
Score = 119 bits (298), Expect = 8e-27
Identities = 76/160 (47%), Positives = 86/160 (53%), Gaps = 21/160 (13%)
Query: 425 GGDRSSGGGYSGDRSGGGYGGDRSGGGYGGDRGGGYGGDRGGGYGGDRGGGYGGDRGGYG 484
G R GGG SG+ G G G+ GGG RGG +GG GGYGG G GG RG YG
Sbjct: 211 GSQRGRGGG-SGNFMGRG--GNFGGGGGNFGRGGNFGGR--GGYGG----GGGGSRGSYG 261
Query: 485 GDRGG--GYGGDRGGYGG-----DRGGYGGDRGGYGGDRGGYGGDRSRGGYGGDRGGGSG 537
G GG G+GGD G YGG RGGYGG GYG GGYGG GGY G GG+
Sbjct: 262 GGDGGYNGFGGDGGNYGGGPGYSSRGGYGGGGPGYGNQGGGYGGG---GGYDGYNEGGN- 317
Query: 538 YGGDRSGGYGGDRSGGGYGGDRGGGYGGDRGG-YGGKMGG 576
+GG GG G G Y G + YG +GG +GG+ G
Sbjct: 318 FGGGNYGGGGNYNDFGNYSGQQQSNYGPMKGGSFGGRSSG 357
Score = 117 bits (292), Expect = 4e-26
Identities = 77/146 (52%), Positives = 87/146 (59%), Gaps = 20/146 (13%)
Query: 438 RSGGGYGGDRSGGGYGGDRGGGYGGDRGGGYGGDRGGGYGGDRGGYGGDRGGGYGGDRGG 497
+S G G G G RGG +GG GG +G RGG +GG RGGYGG G GG RG
Sbjct: 208 QSAGSQRGRGGGSGNFMGRGGNFGGG-GGNFG--RGGNFGG-RGGYGG----GGGGSRGS 259
Query: 498 YGGDRGGYGGDRGGYGGDRGGYGGDRSRGGYGGDRGGGSGYGGDRSGGYGGDRSGGGYGG 557
YGG GGY G GG GG+ GG G SRGGYG GGG GY G++ GGYGG GGGY G
Sbjct: 260 YGGGDGGYNGF-GGDGGNYGGGPGYSSRGGYG---GGGPGY-GNQGGGYGG---GGGYDG 311
Query: 558 -DRGGGYGGDRGGYGGKMGGRNDYRN 582
+ GG +GG G YGG G ND+ N
Sbjct: 312 YNEGGNFGG--GNYGGG-GNYNDFGN 334
Score = 85.5 bits (210), Expect = 1e-16
Identities = 59/114 (51%), Positives = 63/114 (55%), Gaps = 12/114 (10%)
Query: 478 GDRGGYGGDRGGGYGGDRGGYGGDRGGYGGDRGGYGGDRGGY--GGDRSRGGYGGDRGGG 535
G + G GG G G RGG G GG G RGG G RGGY GG SRG YGG GG
Sbjct: 211 GSQRGRGGGSGNFMG--RGGNFGGGGGNFG-RGGNFGGRGGYGGGGGGSRGSYGGGDGGY 267
Query: 536 SGYGGDRSGGYGGD---RSGGGYGGDRGGGYGGDRGGYGGKMGGRNDYRNDQRN 586
+G+GGD G YGG S GGYGG G GYG GGYGG GG D N+ N
Sbjct: 268 NGFGGD-GGNYGGGPGYSSRGGYGGG-GPGYGNQGGGYGG--GGGYDGYNEGGN 317
Score = 50.4 bits (119), Expect = 4e-06
Identities = 54/192 (28%), Positives = 70/192 (36%), Gaps = 47/192 (24%)
Query: 1 MSDSGSYGQSGGEQQSYSTYGNPGSQGYGQASQSYSGYGQTTDSSYGQNYSGYSSYGQSY 60
M G++G GG ++ GN G +G Y G G + SYG GY+ +G
Sbjct: 224 MGRGGNFGGGGG---NFGRGGNFGGRG------GYGGGGGGSRGSYGGGDGGYNGFGGD- 273
Query: 61 SQSYGGYENQKQSSYSQQPYNNQGQQQNMESSGSQGGRAPSYDQP--DYGQQDSYD-QQS 117
GG N G S G GG P Y YG YD
Sbjct: 274 ----GG---------------NYGGGPGYSSRGGYGGGGPGYGNQGGGYGGGGGYDGYNE 314
Query: 118 GYDQHQGSYDEQSNYDQQHDSYSQNQQSYHSQRENYSHHTQDDRRDVSRYGEDNRG--YG 175
G + G+Y NY+ +YS QQS + + S +G + G YG
Sbjct: 315 GGNFGGGNYGGGGNYN-DFGNYSGQQQSNYGPMKGGS------------FGGRSSGSPYG 361
Query: 176 GSQGGGRGRGGY 187
G G G G GGY
Sbjct: 362 GGYGSGGGSGGY 373
Score = 39.7 bits (91), Expect = 0.008
Identities = 40/145 (27%), Positives = 54/145 (37%), Gaps = 16/145 (11%)
Query: 86 QQNMESSGSQGGRAPSYDQPDYGQQDSYDQQSGYDQHQGSYDEQSNYDQ----QHDSYSQ 141
+Q M+S+GSQ GR G+ ++ G G++ + Y SY
Sbjct: 204 KQEMQSAGSQRGRGGGSGN-FMGRGGNFGGGGGNFGRGGNFGGRGGYGGGGGGSRGSYGG 262
Query: 142 NQQSYHS---QRENYSHHTQDDRRDVSRYGEDNRGYGGSQGGGRGRGGYDKDGRGPMTG- 197
Y+ NY R YG GYG GG G GGYD G G
Sbjct: 263 GDGGYNGFGGDGGNYGGGPGYSSR--GGYGGGGPGYGNQGGGYGGGGGYDGYNEGGNFGG 320
Query: 198 ---SSGGDRGGFKNFGGHR--DYGP 217
GG+ F N+ G + +YGP
Sbjct: 321 GNYGGGGNYNDFGNYSGQQQSNYGP 345
Score = 36.2 bits (82), Expect = 0.087
Identities = 31/123 (25%), Positives = 54/123 (43%), Gaps = 17/123 (13%)
Query: 103 DQPDYGQQDSYDQQSGYDQHQGSYDEQSNYDQ--------QHDSYSQNQ-QSYHSQRENY 153
D +Y +D +++ + + D QS + HD+ + Q YH+
Sbjct: 136 DTEEYNLRDYFEKYGKIETIEVMEDRQSGKKRGFAFVTFDDHDTVDKIVVQKYHT----I 191
Query: 154 SHHTQDDRRDVSRYGEDNRGYGGSQGGGRGRGGYDKDGRGPMTGSSGGDRGGFKNFGGHR 213
+ H + ++ +S+ ++ + G +G G G G + GRG G GG+ G NFGG
Sbjct: 192 NGHNCEVKKALSK--QEMQSAGSQRGRGGGSGNFM--GRGGNFGGGGGNFGRGGNFGGRG 247
Query: 214 DYG 216
YG
Sbjct: 248 GYG 250
Score = 32.0 bits (71), Expect = 1.6
Identities = 26/65 (40%), Positives = 30/65 (46%), Gaps = 5/65 (7%)
Query: 168 GEDNRG-YGGSQGGGRGRGGYDKD-GRGPMTGSSGGDRGG---FKNFGGHRDYGPRTDAD 222
G +RG YGG GG G GG + G GP S GG GG + N GG G D
Sbjct: 253 GGGSRGSYGGGDGGYNGFGGDGGNYGGGPGYSSRGGYGGGGPGYGNQGGGYGGGGGYDGY 312
Query: 223 SESDN 227
+E N
Sbjct: 313 NEGGN 317
Score = 30.0 bits (66), Expect = 6.2
Identities = 18/42 (42%), Positives = 20/42 (47%), Gaps = 4/42 (9%)
Query: 177 SQGGGRGRGGYDKDGRGPMTGSSGGDRGGFKNFGGHRDYGPR 218
S G RGRGG G G G G GG NFG ++G R
Sbjct: 209 SAGSQRGRGG----GSGNFMGRGGNFGGGGGNFGRGGNFGGR 246
>gi|62122917 filaggrin family member 2 [Homo sapiens]
Length = 2391
Score = 129 bits (325), Expect = 6e-30
Identities = 175/647 (27%), Positives = 238/647 (36%), Gaps = 98/647 (15%)
Query: 2 SDSGSYGQSG-GEQQS--YSTYGNPGSQGYGQ---ASQSYSGYGQTTDSSYGQNYSGYSS 55
S SYGQ G G QS Y YG+ + G+GQ S +G+GQ S GQ+ SG+
Sbjct: 538 SRQSSYGQHGSGSSQSSGYGQYGSRETSGFGQHGLGSGQSTGFGQYGSGS-GQS-SGFGQ 595
Query: 56 YGQSYSQS--YGGYENQK-QSSYSQQPYNNQ-----GQQQNMESSGSQGGRAPSYDQPDY 107
+G QS +G +E++ QSSY Q + GQ + ++SG + S +
Sbjct: 596 HGSGSGQSSGFGQHESRSGQSSYGQHSSGSSQSSGYGQHGSRQTSGFGQHGSGSSQSTGF 655
Query: 108 GQQDS-YDQQSGYDQHQGSYDEQSNYDQQ-----HDSYSQNQQSYHSQRENYSHHTQDDR 161
GQ S Q SG+ QH + S + Q H SY Q+ SQ Y H
Sbjct: 656 GQYGSGSGQSSGFGQHVSGSGQSSGFGQHESRSGHSSYGQHGFG-SSQSSGYGQHGSSSG 714
Query: 162 RDVSRYGEDNRGYGGSQGGGRGRGGYDKDGRGPMTGSSGGDRGGF---KNFGGHRDYGPR 218
+ S +G+ G S G+ G + GS G GF ++ G YG
Sbjct: 715 Q-TSGFGQHELSSGQSSSFGQHGSGSGQSSGFGQHGSGSGQSSGFGQHESRSGQSSYGQH 773
Query: 219 TDADSESDN-SDNNTIFVQGLGEGVSTDQVGEFFKQIGIIKTNKKTGKPMINLYTDKDTG 277
+ S+S + + G G+ S F Q G + + G + + +G
Sbjct: 774 SSGSSQSSGYGQHGSRQTSGFGQHGSGSSQSTGFGQYG-SGSGQSAGFGQHGSGSGQSSG 832
Query: 278 KPKGEATVSFDDPPSAKAAIDWFDGKEFHGNIIKVSFATRRPEFMRGGGSGGGRRGRGGY 337
+ E+ + G HG+ + + G SG G+ G G
Sbjct: 833 FGQHESRSHQSSYGQHGSGSSQSSGYGQHGSSSGQTSGFGQHRSSSGQYSGFGQHGSGSG 892
Query: 338 RGRG-GFQGRGGDPKSGDWVCPNPSCGNMNFARRNSCNQCNEPRPEDSRPSGGDFRGRGY 396
+ G G G G SG F + S S S G G
Sbjct: 893 QSSGFGQHGTGSGQYSG-------------FGQHES----------RSHQSSYGQHGSGS 929
Query: 397 GGERGYRGRGGRGGDRGGYGGDRSGGGYGGDRSSGGGYSGDRSG--GGYGGDRSGGGYGG 454
GY G G G+G RSG G +SSG G G SG G+G SG G
Sbjct: 930 SQSSGYGQHGSSSGQTFGFGQHRSGSG----QSSGFGQHGSGSGQSSGFGQHESGSGKSS 985
Query: 455 DRG-------------GGYGGDRGGGYGGDRGGGYGGDRGGYGGDR--GGGYGG-DRGGY 498
G G G + GYG + G G G+G R G Y G + G
Sbjct: 986 GFGQHESRSSQSNYGQHGSGSSQSSGYG--QHGSSSGQTTGFGQHRSSSGQYSGFGQHGS 1043
Query: 499 GGDRGGYGGDRGGYGGDRGGYGGDRSR------GGYGGDRGGGSGYG--GDRSG---GYG 547
G D+ G G G G+G SR G +G SGYG G SG G+G
Sbjct: 1044 GSDQSSGFGQHGTGSGQSSGFGQYESRSRQSSYGQHGSGSSQSSGYGQHGSNSGQTSGFG 1103
Query: 548 GDRSGGGYG---GDRGGGYG-----GDRGGYGGKMGG--RNDYRNDQ 584
R G G G G G G G G GK G +++YR+ Q
Sbjct: 1104 QHRPGSGQSSGFGQYGSGSGQSSGFGQHGSGTGKSSGFAQHEYRSGQ 1150
Score = 127 bits (318), Expect = 4e-29
Identities = 168/637 (26%), Positives = 228/637 (35%), Gaps = 70/637 (10%)
Query: 2 SDSGSYGQSGGEQQSYSTYGNPGSQGYGQAS---QSYSGYGQTTDSSYGQN------YSG 52
S S Y Q G S +G GS G GQ+S Q SG GQ+ S +GQ+ SG
Sbjct: 461 SQSLGYDQHGSSSGKTSGFGQHGS-GSGQSSGFGQCGSGSGQS--SGFGQHGSVSGQSSG 517
Query: 53 YSSYGQSYSQS--YGGYENQ-KQSSYSQ-----QPYNNQGQQQNMESSGSQGGRAPSYDQ 104
+ +G QS +G +E++ +QSSY Q + GQ + E+SG S
Sbjct: 518 FGQHGSVSGQSSGFGQHESRSRQSSYGQHGSGSSQSSGYGQYGSRETSGFGQHGLGSGQS 577
Query: 105 PDYGQQDS-YDQQSGYDQHQGSYDEQSNYDQQHDSYSQNQQSYHSQRENYSH-HTQDDRR 162
+GQ S Q SG+ QH + S + Q Q+ HS + S + Q R
Sbjct: 578 TGFGQYGSGSGQSSGFGQHGSGSGQSSGFGQHESRSGQSSYGQHSSGSSQSSGYGQHGSR 637
Query: 163 DVSRYGEDNRGYGGSQGGGR-GRGGYDKDGRGPMTGSSGGDR--GGFKNFGGHRDYGPRT 219
S +G+ G S G G+ G G G G SG G ++ GH YG
Sbjct: 638 QTSGFGQHGSGSSQSTGFGQYGSGSGQSSGFGQHVSGSGQSSGFGQHESRSGHSSYGQHG 697
Query: 220 DADSESD---NSDNNTIFVQGLGEGVSTDQVGEFFKQIGIIKTNKKTGKPMINLYTDKDT 276
S+S +++ G G+ + F Q G + + +G + + +
Sbjct: 698 FGSSQSSGYGQHGSSSGQTSGFGQHELSSGQSSSFGQHG-SGSGQSSGFGQHGSGSGQSS 756
Query: 277 GKPKGEATVSFDDPPSAKAAIDWFDGKEFHGNIIKVSFATRRPEFMRGGGSGGGRRGRGG 336
G + E+ + G HG +R+ GSG + G
Sbjct: 757 GFGQHESRSGQSSYGQHSSGSSQSSGYGQHG--------SRQTSGFGQHGSGSSQSTGFG 808
Query: 337 YRGRGGFQGRG-GDPKSGDWVCPNPSCGNMNFARRNSCNQCNEPRPEDSRPSGGDFRGRG 395
G G Q G G SG S G R+ + + S+ SG G
Sbjct: 809 QYGSGSGQSAGFGQHGSGS----GQSSGFGQHESRSHQSSYGQHGSGSSQSSGYGQHGSS 864
Query: 396 YGGERGYRGRGGRGGDRGGYGGDRSGGGYGGDRSSGGGYSGDRSGGGYGGDRSGGGYGGD 455
G G+ G G+G SG G G SG SG G RS G
Sbjct: 865 SGQTSGFGQHRSSSGQYSGFGQHGSGSGQSSGFGQHGTGSGQYSGFGQHESRSHQSSYGQ 924
Query: 456 RGGGYGGDRGGGYGGDRGG---GYGGDRGGYGGDRGGGYGGDRGGYGGDRGGYGGDRGGY 512
G G G G G G G+G R G G G G G G G+G G
Sbjct: 925 HGSGSSQSSGYGQHGSSSGQTFGFGQHRSGSGQSSG---FGQHGSGSGQSSGFGQHESG- 980
Query: 513 GGDRGGYGGDRSR------GGYGGDRGGGSGYG--GDRSG---GYGGDRSGGGY------ 555
G G+G SR G +G SGYG G SG G+G RS G
Sbjct: 981 SGKSSGFGQHESRSSQSNYGQHGSGSSQSSGYGQHGSSSGQTTGFGQHRSSSGQYSGFGQ 1040
Query: 556 ---GGDRGGGYGGDRGGYGGKMGGRNDYRNDQRNRPY 589
G D+ G+ G G G+ G Y + R Y
Sbjct: 1041 HGSGSDQSSGF-GQHGTGSGQSSGFGQYESRSRQSSY 1076
Score = 125 bits (313), Expect = 1e-28
Identities = 168/656 (25%), Positives = 234/656 (35%), Gaps = 98/656 (14%)
Query: 5 GSYGQSGGEQQSY-STYGNPGSQGYGQASQSYSGYGQTTDSSYGQNYSGYSSYGQSYSQS 63
G ++G Q S YG+ GSQ Y G+ ++SS +S YG SQS
Sbjct: 367 GGQWRTGSSQSSCCGQYGSGGSQSCSNGQHEYGSCGRFSNSSSSNEFSKCDQYGSGSSQS 426
Query: 64 ------------YGGYE----------NQKQSSYSQ-----QPYNNQGQQQNMESSGSQG 96
G+E Q +S+ SQ Q ++ G+ GS
Sbjct: 427 TSFEQHGTGLSQSSGFEQHVCGSGQTCGQHESTSSQSLGYDQHGSSSGKTSGFGQHGSGS 486
Query: 97 GRAPSYDQ--------PDYGQQDSYD-QQSGYDQHQGSYDEQSNYDQQHDSYSQNQQSY- 146
G++ + Q +GQ S Q SG+ QH GS QS+ QH+S S+ Q SY
Sbjct: 487 GQSSGFGQCGSGSGQSSGFGQHGSVSGQSSGFGQH-GSVSGQSSGFGQHESRSR-QSSYG 544
Query: 147 --HSQRENYSHHTQDDRRDVSRYGEDNRGYGGSQGGGR-GRGGYDKDGRGPMTGSSGGDR 203
S S + Q R+ S +G+ G G S G G+ G G G G GS G
Sbjct: 545 QHGSGSSQSSGYGQYGSRETSGFGQHGLGSGQSTGFGQYGSGSGQSSGFG-QHGSGSGQS 603
Query: 204 GGF---KNFGGHRDYGPRTDADSESDN-SDNNTIFVQGLGEGVSTDQVGEFFKQIGIIKT 259
GF ++ G YG + S+S + + G G+ S F Q G +
Sbjct: 604 SGFGQHESRSGQSSYGQHSSGSSQSSGYGQHGSRQTSGFGQHGSGSSQSTGFGQYG-SGS 662
Query: 260 NKKTGKPMINLYTDKDTGKPKGEATVSFDDPPSAKAAIDWFDGKEFHGNIIKVSFATRRP 319
+ +G + + +G + E+ G HG+ + +
Sbjct: 663 GQSSGFGQHVSGSGQSSGFGQHESRSGHSSYGQHGFGSSQSSGYGQHGSSSGQTSGFGQH 722
Query: 320 EFMRGGGSGGGRRGRGGYRGRGGFQGRGGDPKSGDWVCPNPSCGNMNFARRNSCNQCNEP 379
E G S G+ G G + G Q G +S + G ++ + +S
Sbjct: 723 ELSSGQSSSFGQHGSGSGQSSGFGQHGSGSGQSSGFGQHESRSGQSSYGQHSS------- 775
Query: 380 RPEDSRPSGGDFRGRGYG--GER---GYRGRGGRGGDRGGYGGDRSGGGYGGDRSSGGGY 434
G + GYG G R G+ G G+G SG G G
Sbjct: 776 ---------GSSQSSGYGQHGSRQTSGFGQHGSGSSQSTGFGQYGSGSGQSAGFGQHGSG 826
Query: 435 SGDRSGGGYGGDRSGGGYGGDRGGGYGGDRGGGYGGDRGG---GYGGDRGGYGGDRGGGY 491
SG SG G RS G G G G G G G G+G R G G G
Sbjct: 827 SGQSSGFGQHESRSHQSSYGQHGSGSSQSSGYGQHGSSSGQTSGFGQHRSSSGQYSGFGQ 886
Query: 492 GGDRGGYGGDRGGYGGDRGGYGGDRGGYGGDRSR------GGYGGDRGGGSGYG--GDRS 543
G G G +G G Y G+G SR G +G SGYG G S
Sbjct: 887 HGSGSGQSSGFGQHGTGSGQY----SGFGQHESRSHQSSYGQHGSGSSQSSGYGQHGSSS 942
Query: 544 G---GYGGDRSGGGY---------GGDRGGGYGGDRGGYGGKMG-GRNDYRNDQRN 586
G G+G RSG G G + G+G G G G G+++ R+ Q N
Sbjct: 943 GQTFGFGQHRSGSGQSSGFGQHGSGSGQSSGFGQHESGSGKSSGFGQHESRSSQSN 998
Score = 120 bits (302), Expect = 3e-27
Identities = 169/650 (26%), Positives = 221/650 (34%), Gaps = 104/650 (16%)
Query: 4 SGSYGQSGGEQQSYSTYGNPGS-----QGYGQ---ASQSYSGYGQ----TTDSSYGQNYS 51
S +GQ G S +G GS G+GQ S SG+GQ + SSYGQ+ S
Sbjct: 489 SSGFGQCGSGSGQSSGFGQHGSVSGQSSGFGQHGSVSGQSSGFGQHESRSRQSSYGQHGS 548
Query: 52 GYSSYGQSYSQSYGGYENQKQSSYSQQPYNNQGQQQNMESSGSQGGRAPSYDQ------- 104
G S S YG Y +++ S + Q + GQ GS G++ + Q
Sbjct: 549 G-----SSQSSGYGQYGSRETSGFGQHGLGS-GQSTGFGQYGSGSGQSSGFGQHGSGSGQ 602
Query: 105 -PDYGQQDSYDQQSGYDQHQGSYDEQSNYDQ----------QHDSYSQNQQSY------H 147
+GQ +S QS Y QH + S Y Q QH S S +
Sbjct: 603 SSGFGQHESRSGQSSYGQHSSGSSQSSGYGQHGSRQTSGFGQHGSGSSQSTGFGQYGSGS 662
Query: 148 SQRENYSHHTQDDRRDVSRYGEDNRGYGGSQGGGRGRGGYDKDGRGPMTGSSGGDRGGFK 207
Q + H + S +G+ G S G G G G G GSS G GF
Sbjct: 663 GQSSGFGQHVSGSGQS-SGFGQHESRSGHSSYGQHGFGSSQSSGYG-QHGSSSGQTSGF- 719
Query: 208 NFGGHR-DYGPRTDADSESDNSDNNTIFVQ-GLGEGVSTDQVGEFFKQIGIIKTNKKTGK 265
G H G + S ++ F Q G G G S+ F Q G+
Sbjct: 720 --GQHELSSGQSSSFGQHGSGSGQSSGFGQHGSGSGQSSG-----FGQHESRSGQSSYGQ 772
Query: 266 PMINLYTDKDTGKPKGEATVSFDDPPSAKAAIDWFDGKEFHGNIIKVSFATRRPEFMRGG 325
G+ T F S + F G+ G+ F G
Sbjct: 773 HSSGSSQSSGYGQHGSRQTSGFGQHGSGSSQSTGF-GQYGSGSGQSAGFGQHGSG--SGQ 829
Query: 326 GSGGGRRGRGGYRGRGGFQGRGGDPKSGDWVCPNPSCGNMNFARRNSCNQCNEPRPEDSR 385
SG G+ ++ G G G SG + S F + S + +
Sbjct: 830 SSGFGQHESRSHQSSYGQHGSGSSQSSGYGQHGSSSGQTSGFGQHRSSS---------GQ 880
Query: 386 PSGGDFRGRGYGGERGYRGRGGRGGDRGGYGGDRSGG--------GYGGDRSSGGGYSGD 437
SG G G G G+ G G G+G S G G +SSG G G
Sbjct: 881 YSGFGQHGSGSGQSSGFGQHGTGSGQYSGFGQHESRSHQSSYGQHGSGSSQSSGYGQHGS 940
Query: 438 RSGG--GYGGDRSGGGYG---GDRGGGYGGDRGGGY---GGDRGGGYG-----GDRGGYG 484
SG G+G RSG G G G G G G G G + G+G + YG
Sbjct: 941 SSGQTFGFGQHRSGSGQSSGFGQHGSGSGQSSGFGQHESGSGKSSGFGQHESRSSQSNYG 1000
Query: 485 GDRGGGYGGDRGGYGGDRGGYGGDRGGYGGDRGGYGGDRSRG--GYGGDRGGGSGYGGDR 542
+ G GYG G G G+G R G G G G D+ G G G
Sbjct: 1001 --QHGSGSSQSSGYG-QHGSSSGQTTGFGQHRSSSGQYSGFGQHGSGSDQSSGFGQHGTG 1057
Query: 543 SG---GYGGDRSGG--------GYGGDRGGGYGGDRGGYGGKMGGRNDYR 581
SG G+G S G G + GY G G G+ G +R
Sbjct: 1058 SGQSSGFGQYESRSRQSSYGQHGSGSSQSSGY-GQHGSNSGQTSGFGQHR 1106
Score = 116 bits (291), Expect = 5e-26
Identities = 154/613 (25%), Positives = 217/613 (35%), Gaps = 75/613 (12%)
Query: 2 SDSGSYGQSGGEQQS-YSTYGNPGSQG-----YGQASQSYSGYGQTTDSS-----YGQNY 50
S S YGQ G Q S + +G+ SQ YG S SG+GQ S +GQ+
Sbjct: 626 SQSSGYGQHGSRQTSGFGQHGSGSSQSTGFGQYGSGSGQSSGFGQHVSGSGQSSGFGQHE 685
Query: 51 S--GYSSYGQSYSQSYGGYENQKQSSYSQQPYNNQGQQQNMESSGSQGGRAPSYDQPDYG 108
S G+SSYGQ G+ + + S Y Q ++ GQ G++ S+ Q G
Sbjct: 686 SRSGHSSYGQH------GFGSSQSSGYGQHG-SSSGQTSGFGQHELSSGQSSSFGQHGSG 738
Query: 109 QQDSYDQQSGYDQHQGSYDEQSNYDQQHDSYSQNQQSYHSQRENYSH-HTQDDRRDVSRY 167
Q SG+ QH + S + Q Q+ HS + S + Q R S +
Sbjct: 739 S----GQSSGFGQHGSGSGQSSGFGQHESRSGQSSYGQHSSGSSQSSGYGQHGSRQTSGF 794
Query: 168 GEDNRGYGGSQGGGRGRGGYDKDGRGPMTGSSGGDRGGFKNFGGHRD------YGPRTDA 221
G+ G G SQ G G+ G G+ G G G FG H YG
Sbjct: 795 GQ--HGSGSSQSTGFGQYG-SGSGQSAGFGQHGSGSGQSSGFGQHESRSHQSSYGQHGSG 851
Query: 222 DSESDN-SDNNTIFVQGLGEGVSTDQVGEF--FKQIGIIKTNKKTGKPMINLYTDKDTGK 278
S+S + + Q G G G++ F Q G + + +G + + +G
Sbjct: 852 SSQSSGYGQHGSSSGQTSGFGQHRSSSGQYSGFGQHGS-GSGQSSGFGQHGTGSGQYSGF 910
Query: 279 PKGEATVSFDDPPSAKAAIDWFDGKEFHGNIIKVSFATRRPEFMRGGGSGGGRRGRGGYR 338
+ E+ + G HG+ +F + G SG G+ G G +
Sbjct: 911 GQHESRSHQSSYGQHGSGSSQSSGYGQHGSSSGQTFGFGQHRSGSGQSSGFGQHGSGSGQ 970
Query: 339 GRGGFQGRGGDPKSGDWVCPNPSCGNMNFARRNSCNQCNEPRPEDSRPSG---GDFRGRG 395
G Q G KS + N+ + S + + + SG G + R
Sbjct: 971 SSGFGQHESGSGKSSGFGQHESRSSQSNYGQHGSGSSQSSGYGQHGSSSGQTTGFGQHRS 1030
Query: 396 YGGERGYRGRGGRGGDRG------GYGGDRSGG----------------GYGGDRSSGGG 433
G+ G+ G G D+ G G +S G G G +SSG G
Sbjct: 1031 SSGQYSGFGQHGSGSDQSSGFGQHGTGSGQSSGFGQYESRSRQSSYGQHGSGSSQSSGYG 1090
Query: 434 YSGDRSG--GGYGGDRSGGGYG---GDRGGGYG-----GDRGGGYGGDRGGGYGGDRGGY 483
G SG G+G R G G G G G G G G G G G R G
Sbjct: 1091 QHGSNSGQTSGFGQHRPGSGQSSGFGQYGSGSGQSSGFGQHGSGTGKSSGFAQHEYRSGQ 1150
Query: 484 GGDRGGGYGGDRGGYGGDRGGYGGDRGGYGGDRGGYGGDRSRGGYGGDRGGGSGYGGDRS 543
G G + G G +G G S G + D G +G+G S
Sbjct: 1151 SSYGQHGTGSSQSSGCGQHESGSGPTTSFGQHVSGSDNFSSSGQHISDSGQSTGFGQYGS 1210
Query: 544 GGYGGDRSGGGYG 556
G G +G G G
Sbjct: 1211 G--SGQSTGLGQG 1221
Score = 85.9 bits (211), Expect = 1e-16
Identities = 151/594 (25%), Positives = 212/594 (35%), Gaps = 85/594 (14%)
Query: 2 SDSGSYGQSGGEQQSYSTYGNPGSQ-----GYGQ---ASQSYSGYGQTTDSSYGQNYSGY 53
S +YGQ G S YG GS G+GQ +S YSG+GQ S + G
Sbjct: 994 SSQSNYGQHGSGSSQSSGYGQHGSSSGQTTGFGQHRSSSGQYSGFGQHGSGSDQSSGFGQ 1053
Query: 54 SSYGQSYSQSYGGYENQ-KQSSYSQQPYNNQGQQQNMESSGSQGGRAPSYDQPDYGQQDS 112
G S +G YE++ +QSSY Q + Q GS G+ + Q G
Sbjct: 1054 HGTGSGQSSGFGQYESRSRQSSYGQHG-SGSSQSSGYGQHGSNSGQTSGFGQHRPGS--- 1109
Query: 113 YDQQSGYDQHQGSYDEQSNYDQQHDSYSQNQQSYHSQRENYSHHTQDDRRDVSRYGEDNR 172
Q SG+ Q+ GS QS+ QH S + + ++ H + R S YG+
Sbjct: 1110 -GQSSGFGQY-GSGSGQSSGFGQHGSGT-------GKSSGFAQH--EYRSGQSSYGQ--H 1156
Query: 173 GYGGSQGGGRGRGGYDKDGRGPMT--GSSGGDRGGFKNFGGH-RDYGPRTDADSESDNSD 229
G G SQ G G+ + G GP T G F + G H D G T S
Sbjct: 1157 GTGSSQSSGCGQ---HESGSGPTTSFGQHVSGSDNFSSSGQHISDSGQSTGFGQYGSGSG 1213
Query: 230 NNTIFVQGLGEGVSTDQVGEFFKQIGIIKTNKKTGKPMINLYTDKDTGKPKGEATVSFDD 289
+T GLG+G S QV G +T T IN +G+ + T S
Sbjct: 1214 QST----GLGQGES-QQVESGSTVHGRQET---THGQTINTTRHSQSGQGQSTQTGSRVT 1265
Query: 290 PPSAKAAIDWFDGKEFHGNII---KVSFATRRPEFMRGGGSGGGRR-----GRGGYRGRG 341
+ + D E H + T+ GS RR G+ G R
Sbjct: 1266 RRRRSSQSENSD-SEVHSKVSHRHSEHIHTQAGSHYPKSGSTVRRRQGTTHGQRGDTTRH 1324
Query: 342 GFQGRGGDPKSGDWVCPNPSCGNMNFARRNSCNQCNEPRPEDSRPSGGDFRGRGYGGERG 401
G G G ++G + + G F+ ++ DS G R + E+
Sbjct: 1325 GHSGHGQSTQTG-----SRTSGRQRFSHSDA---------TDSEVHSG-VSHRPHSQEQT 1369
Query: 402 YRGRGGRGGDRGGYGGDRSGGGYGGDRSSGGGYSGDRSGGGYGGDRSGGGYGGDRGGGYG 461
+ G + G+ +R Y G +G+ +G G+ SG G RG
Sbjct: 1370 HSQAGSQHGESESTVHERHETTY--------GQTGEATGHGH----SGHGQSTQRGSRTT 1417
Query: 462 GDRGGGY--GGDRGGGYGGDRGGYGGDRGGGYGGDRGGYGGDR-GGYGGDRGGYGGD--- 515
G RG G+ D GG ++ G G + G G G G G GD
Sbjct: 1418 GRRGSGHSESSDSEVHSGGSHRPQSQEQTHGQAGSQHGESGSTVHGRHGTTHGQTGDTTR 1477
Query: 516 --RGGYGGDRSRG-GYGGDRGGGSGYGGDRSGGYGGDRSGGGYGGDRGGGYGGD 566
+G RG G RG G D GG + G+ + G G+
Sbjct: 1478 HAHYHHGKSTQRGSSTTGRRGSGHSESSDSEVHSGGSHTHSGHTHGQSGSQHGE 1531
Score = 81.3 bits (199), Expect = 2e-15
Identities = 150/671 (22%), Positives = 217/671 (32%), Gaps = 103/671 (15%)
Query: 3 DSGSYGQSGGEQQSYSTYGNPG-------SQGYGQASQSYSGYGQTTDSSYGQNYSGYSS 55
+SG +SG S+ G+ G S ++QS + S G SG S
Sbjct: 218 ESGEEYESGSGSNSWERKGHGGLSCGLETSGHESNSTQSRIREQKLGSSCSGSGDSGRRS 277
Query: 56 YGQSYSQSYG-GYENQKQSSYSQQPYNNQGQQQNMESSGSQGGR---------------- 98
+ YS S G G SS + QG Q + SG Q G
Sbjct: 278 HACGYSNSSGCGRPQNASSSCQSHRFGGQGNQFSYIQSGCQSGIKGGQGHGCVSGGQPSG 337
Query: 99 ---------APSYDQPDYGQQDSYDQQSGYDQHQ------------GSYDEQSNYDQQHD 137
+ SY Q YG +++ Q+ Q + GS QS + QH+
Sbjct: 338 CGQPESNPCSQSYSQRGYGARENGQPQNCGGQWRTGSSQSSCCGQYGSGGSQSCSNGQHE 397
Query: 138 SYSQNQQSYHSQRENYSHHTQDDRRDVSRYGEDNRGYGGSQGGGRGR---GGYDKDGRGP 194
S + S S +S Q + G G SQ G + G G+
Sbjct: 398 YGSCGRFSNSSSSNEFSKCDQYGSGSSQSTSFEQHGTGLSQSSGFEQHVCGSGQTCGQHE 457
Query: 195 MTGSS-------GGDRGGFKNFGGHRDYGPRTDADSESDNSDNNTIFVQGLGEGVSTDQV 247
T S G G FG H ++ + + + G G+ S
Sbjct: 458 STSSQSLGYDQHGSSSGKTSGFGQHGSGSGQSSGFGQCGSGSGQS---SGFGQHGSVSGQ 514
Query: 248 GEFFKQIGIIKTNKKTGKPMINLYTDKDTGKPKGEATVSFDDPPSAKAAIDWFDGKEFHG 307
F Q G + + + +G + + + G + S + + +E G
Sbjct: 515 SSGFGQHGSV-SGQSSGFGQHESRSRQSSYGQHGSGS-------SQSSGYGQYGSRETSG 566
Query: 308 ---NIIKVSFATRRPEFMRGGG--SGGGRRGRGGYR--GRGGFQGRGGDPKSGDWVCPNP 360
+ + +T ++ G G SG G+ G G + G G + R G G +
Sbjct: 567 FGQHGLGSGQSTGFGQYGSGSGQSSGFGQHGSGSGQSSGFGQHESRSGQSSYGQHSSGSS 626
Query: 361 SCGNMNFARRNSCNQCNEPRPEDSRPSGGDFRGRGYGGERGYRGRGGRGGDRGGYG--GD 418
+ + S+ +G G G G G+ G G+G
Sbjct: 627 QSSGYGQHGSRQTSGFGQHGSGSSQSTGFGQYGSGSGQSSGFGQHVSGSGQSSGFGQHES 686
Query: 419 RSG------GGYGGDRSSGGGYSGDRSG--GGYGGDRSGGGYG---GDRGGGYG-----G 462
RSG G+G +SSG G G SG G+G G G G G G G
Sbjct: 687 RSGHSSYGQHGFGSSQSSGYGQHGSSSGQTSGFGQHELSSGQSSSFGQHGSGSGQSSGFG 746
Query: 463 DRGGGYGGDRGGGYGGDRGGY--------GGDRGGGYG--GDRGGYG-GDRGGYGGDRGG 511
G G G G G R G G + GYG G R G G G G
Sbjct: 747 QHGSGSGQSSGFGQHESRSGQSSYGQHSSGSSQSSGYGQHGSRQTSGFGQHGSGSSQSTG 806
Query: 512 YGGDRGGYGGDRSRGGYGGDRGGGSGYGGDRSGGYGGDRSGGGYGGDRGGGYGGDRGGYG 571
+G G G G +G G SG+G S + G G + GY G G
Sbjct: 807 FGQYGSGSGQSAGFGQHGSGSGQSSGFGQHESRSHQSSYGQHGSGSSQSSGY-GQHGSSS 865
Query: 572 GKMGGRNDYRN 582
G+ G +R+
Sbjct: 866 GQTSGFGQHRS 876
Score = 56.2 bits (134), Expect = 8e-08
Identities = 141/681 (20%), Positives = 213/681 (31%), Gaps = 121/681 (17%)
Query: 7 YGQSGGEQQSYSTYGNPGSQGYGQASQS--YSGYGQTTDSSYGQNYSGYSSYGQSYS--- 61
Y Q+ ST G GS G+ ++S S +SG G T S + SG S +G+S S
Sbjct: 1481 YHHGKSTQRGSSTTGRRGS-GHSESSDSEVHSG-GSHTHSGHTHGQSG-SQHGESESIIH 1537
Query: 62 ---------------QSYGGYENQKQSSYSQQPYNNQGQQQNMESSGSQGG-RAPSYDQP 105
SY G+E Q+ ++ +S GG P +
Sbjct: 1538 DRHRITHGQTGDTTRHSYSGHEQTTQTGSRTTGRQRTSHSESTDSEVHSGGSHRPHSREH 1597
Query: 106 DYGQQDSYDQQSGYDQHQ------GSYDEQSNYDQQHDSYSQNQQSYHSQRENYSHHTQD 159
YGQ S ++ + H+ G + + + S + S + R+ SH
Sbjct: 1598 TYGQAGSQHEEPEFTVHERHGTTHGQIGDTTGHSHSGHGQSTQRGSRTTGRQRSSHSESS 1657
Query: 160 DRRDVSRYGEDNRGYGGSQGGGR-GRG-GYDKDGRGPMTGSSG----------------G 201
D S + G+ Q G + G+ + G G +G G
Sbjct: 1658 DSEVHSGVSHTHTGHTHGQAGSQHGQSESIVPERHGTTHGQTGDTTRHAHYHHGLTTQTG 1717
Query: 202 DRGGFKNFGGHRDY----GPRTDADSESDNSDNNTIFVQGLGEGVSTDQVGEFFKQIGII 257
R + GH +Y G + + S ++ G E + ++ G Q G
Sbjct: 1718 SRTTGRRGSGHSEYSDSEGYSGVSHTHSGHTHGQARSQHGESESIVHERHGTIHGQTGDT 1777
Query: 258 KTNKKTGKPMINLYTDKDTGK--------PKGEATVSFDDPPSAKAAIDWFDGKEFHG-- 307
+ +G + TG+ E F P ++ G + HG
Sbjct: 1778 TRHAHSGHGQSTQTGSRTTGRRSSGHSEYSDSEGHSGFSQRPHSRGHTHGQAGSQ-HGES 1836
Query: 308 -NIIKVSFATRRPEFMRGGGSGGGRRGRG----------GYRGRGGFQGRGGDPKSGDWV 356
+I+ T + G SG + G G G R G + + SG
Sbjct: 1837 ESIVDERHGTTHGQ--TGDTSGHSQSGHGQSTQSGSSTTGRRRSGHSESSDSEVHSGGSH 1894
Query: 357 CPNPSCGNMNFARRNSCNQCNEPRPEDSRPSGGDFRGRGYGG-----ERGYRGRGGRGGD 411
+ + ++ R + + GD G+ + G R G RG
Sbjct: 1895 THSGHTHSQARSQHGESESTVHKRHQTTHGQTGDTTEHGHPSHGQTIQTGSRTTGRRGSG 1954
Query: 412 RGGYGGDRSGGGYGGDRSSGGGYSGDRSGGGYG------GDRSGGGYG--------GDRG 457
Y G S G++ ++G Y +R G +G G G
Sbjct: 1955 HSEYSDSEGPSGVSHTHS---GHTHGQAGSHYPESGSSVHERHGTTHGQTADTTRHGHSG 2011
Query: 458 GGYGGDRGGGYGGDRGGGYG--GDRGGYGGDRGGGYGGDRGGYGGDRGGYG-------GD 508
G RG G R G+ D G+ G G G G G G G
Sbjct: 2012 HGQSTQRGSRTTGRRASGHSEYSDSEGHSGVSHTHSGHAHGQAGSQHGESGSSVHERHGT 2071
Query: 509 RGGYGGD-----RGGYGGDRSRGG-YGGDRGGGSGYGGDRS--GGYGGDRSGGGYG---- 556
G GD G+G RG G RG G D G SG YG
Sbjct: 2072 THGQTGDTTRHAHSGHGQSTQRGSRTAGRRGSGHSESSDSEVHSGVSHTHSGHTYGQARS 2131
Query: 557 --GDRGGGYGGDRGGYGGKMG 575
G+ G G +G G+ G
Sbjct: 2132 QHGESGSAIHGRQGTIHGQTG 2152
Score = 55.5 bits (132), Expect = 1e-07
Identities = 128/571 (22%), Positives = 182/571 (31%), Gaps = 80/571 (14%)
Query: 12 GEQQS--YSTYGNPGSQGYGQASQSYSGYGQTTDSSYGQNYSGYSSYGQS-YSQSYGGYE 68
GE +S + +G Q ++SG+GQ+T + G +G S G S YS S G
Sbjct: 1757 GESESIVHERHGTIHGQTGDTTRHAHSGHGQSTQT--GSRTTGRRSSGHSEYSDSEG--- 1811
Query: 69 NQKQSSYSQQPYNNQGQQQNMESSGSQGGRAPSYDQPDYGQ------QDSYDQQSGYDQH 122
S +SQ+P++ + +GSQ G + S +G S QSG+ Q
Sbjct: 1812 ---HSGFSQRPHS---RGHTHGQAGSQHGESESIVDERHGTTHGQTGDTSGHSQSGHGQS 1865
Query: 123 QGSYDEQSNYDQQHDSYSQNQQSYHSQRENYSHHTQDDRRDVSRYGEDNRGYGG------ 176
S + + S S + + + +S HT R S++GE
Sbjct: 1866 TQSGSSTTGRRRSGHSESSDSEVHSGGSHTHSGHTHSQAR--SQHGESESTVHKRHQTTH 1923
Query: 177 SQGGGRGRGGYDKDGRGPMTGSSGGDRGGFKNFGGHRDYGPRTDADSESDNSDNNTIFVQ 236
Q G G+ G+ TGS R G GH +Y +DSE + ++T
Sbjct: 1924 GQTGDTTEHGHPSHGQTIQTGSRTTGRRG----SGHSEY-----SDSEGPSGVSHT---- 1970
Query: 237 GLGEGVSTDQVGEFFKQIGIIKTNKKTGKPMINLYTDKDTGKPKGEATVSFDDPPSAKAA 296
G + Q G + + G + T + G++T +A+
Sbjct: 1971 --HSGHTHGQAGSHYPESGSSVHERHGTTHGQTADTTRHGHSGHGQSTQRGSRTTGRRAS 2028
Query: 297 -IDWFDGKEFHGNIIKVSFATRRPEFMRGGGSGGGRRGRGGYRGRGGFQGRGGDPKSGDW 355
+ E H + + GS G G + G G+ GD
Sbjct: 2029 GHSEYSDSEGHSGVSHTHSGHAHGQ----AGSQHGESGSSVHERHGTTHGQTGDTTRHAH 2084
Query: 356 VCPNPSC--GNMNFARRNSCNQCNEPRPEDSRPSGG---DFRGRGYGGERGYRGRGG--- 407
S G+ RR S DS G G YG R G G
Sbjct: 2085 SGHGQSTQRGSRTAGRRGS----GHSESSDSEVHSGVSHTHSGHTYGQARSQHGESGSAI 2140
Query: 408 --RGGDRGGYGGDRSGGGYGGDRSSGGGYSGDRSGGGYGGDRSGGGYGGDRGGGYGGDRG 465
R G G GD + G SG G S G RS D
Sbjct: 2141 HGRQGTIHGQTGDTTRHG-----QSGHGQSTQTGSRTTGRQRSSHSESSD---------- 2185
Query: 466 GGYGGDRGGGYGGDRGGYGGDRGGGYGGDRGGYGGDRGGYGGDRGGYGGDRGGYGGDRSR 525
+ + G G R G G G G G GD + GYG R
Sbjct: 2186 SEVHSEASPTHSGHTHSQAGSRHGQSGSSGHGRQGTTHGQTGDTTRHA--HYGYGQSTQR 2243
Query: 526 GG-YGGDRGGGSGYGGDRSGGYGGDRSGGGY 555
G G RG G D G + G+
Sbjct: 2244 GSRTTGRRGSGHSESSDSEVHSWGSHTHSGH 2274
Score = 52.4 bits (124), Expect = 1e-06
Identities = 65/262 (24%), Positives = 102/262 (38%), Gaps = 35/262 (13%)
Query: 2 SDSGSYGQSGGEQQSYSTYGNPGSQGYGQA----SQSYSGYGQT-TDSSYGQNYSGYSSY 56
+D+ +G SG Q + G + G + S+ +SG T + ++GQ S +
Sbjct: 2002 ADTTRHGHSGHGQSTQRGSRTTGRRASGHSEYSDSEGHSGVSHTHSGHAHGQAGSQHGES 2061
Query: 57 GQSYSQSYGGYENQKQSSYSQQPYNNQGQ--QQNMESSGSQG-GRAPSYDQP-------- 105
G S + +G Q + ++ ++ GQ Q+ ++G +G G + S D
Sbjct: 2062 GSSVHERHGTTHGQTGDT-TRHAHSGHGQSTQRGSRTAGRRGSGHSESSDSEVHSGVSHT 2120
Query: 106 ----DYGQQDSYDQQSGYDQH--QGSYDEQSNYDQQHDSYSQNQQ----SYHSQRENYSH 155
YGQ S +SG H QG+ Q+ +H Q S + R+ SH
Sbjct: 2121 HSGHTYGQARSQHGESGSAIHGRQGTIHGQTGDTTRHGQSGHGQSTQTGSRTTGRQRSSH 2180
Query: 156 HTQDDRRDVSRYGEDNRGYGGSQGGGR-GRGGYDKDGRGPMTGSSGGDRGGFKNFG---- 210
D S + G+ SQ G R G+ G GR T GD ++G
Sbjct: 2181 SESSDSEVHSEASPTHSGHTHSQAGSRHGQSGSSGHGRQGTTHGQTGDTTRHAHYGYGQS 2240
Query: 211 ---GHRDYGPRTDADSESDNSD 229
G R G R SES +S+
Sbjct: 2241 TQRGSRTTGRRGSGHSESSDSE 2262
Score = 45.4 bits (106), Expect = 1e-04
Identities = 125/600 (20%), Positives = 193/600 (32%), Gaps = 119/600 (19%)
Query: 5 GSYGQSGGEQQSY--STYGNPGSQGYGQASQSYSGYGQTTDS---SYGQNYSGYSSYGQS 59
G G GE +S +G Q + S SG+GQ+T S + G+ SG+S S
Sbjct: 1827 GQAGSQHGESESIVDERHGTTHGQTGDTSGHSQSGHGQSTQSGSSTTGRRRSGHSESSDS 1886
Query: 60 YSQSYGGYENQKQS---SYSQQPYNNQGQQQNMESSGSQGGRAPSYDQPDYGQ------- 109
S G + + + + SQ + + +++ Q G + P +GQ
Sbjct: 1887 EVHSGGSHTHSGHTHSQARSQHGESESTVHKRHQTTHGQTGDTTEHGHPSHGQTIQTGSR 1946
Query: 110 ------------QDSYDQQSGYDQHQGSYDEQ--SNYDQQHDSYSQNQQSYHSQ-----R 150
DS H G Q S+Y + S + + H Q R
Sbjct: 1947 TTGRRGSGHSEYSDSEGPSGVSHTHSGHTHGQAGSHYPESGSSVHERHGTTHGQTADTTR 2006
Query: 151 ENYSHHTQDDRRDVSRYGEDNRGYGGSQGGGRGRGGYDKDGRGPMTGSSGGDRGGFKNFG 210
+S H Q +R GS+ GR
Sbjct: 2007 HGHSGHGQSTQR-------------GSRTTGR-------------------------RAS 2028
Query: 211 GHRDYGPRTDADSESDNSDNNTIFVQGLGEGVSTDQVGEFFKQIGII--KTNKKTGKPMI 268
GH +Y +DSE + ++T G G + Q GE + T+ +TG
Sbjct: 2029 GHSEY-----SDSEGHSGVSHT--HSGHAHGQAGSQHGESGSSVHERHGTTHGQTGDTTR 2081
Query: 269 NLYTDKDTGKPKGEATVSFDDPPSAKAAIDWFDGKEFHGNIIKV----SFATRRPEFMRG 324
+ ++ +G T ++++ E H + ++ R +
Sbjct: 2082 HAHSGHGQSTQRGSRTAGRRGSGHSESS-----DSEVHSGVSHTHSGHTYGQARSQHGES 2136
Query: 325 GGSGGGRR----GRGGYRGRGGFQGRGGDPKSGDWVCPNPSCGNMNFARRNSCNQCNEPR 380
G + GR+ G+ G R G G G ++G + + G + S + +E
Sbjct: 2137 GSAIHGRQGTIHGQTGDTTRHGQSGHGQSTQTG-----SRTTGRQRSSHSESSD--SEVH 2189
Query: 381 PEDSRPSGGDFRGRGYGGERGYRGRGGRG--GDRGGYGGD---RSGGGYGGDRSSGGGYS 435
E S G + G G G G G G G GD + GYG G +
Sbjct: 2190 SEASPTHSGHTHSQA-GSRHGQSGSSGHGRQGTTHGQTGDTTRHAHYGYGQSTQRGSRTT 2248
Query: 436 GDR-SGGGYGGDRSGGGYGGDRGGGYGGDRGGGYGGDRGGGYGGDRGGYGGDRGGGYGGD 494
G R SG D +G G+ + G G G G G
Sbjct: 2249 GRRGSGHSESSDSEVHSWGSHTHSGHIQGQAGSQQRQPGSTVHGRLETTHGQTGDTTRHG 2308
Query: 495 RGGYG-----GDRGGYGGDRGGYGGDRGGYGGDR--SRGGYGGDR--GGGSGYGGDRSGG 545
GYG G R + +R +G + G YG G +GYG SGG
Sbjct: 2309 HSGYGQSTQTGSRSSRASHFQSHSSERQRHGSSQVWKHGSYGPAEYDYGHTGYG--PSGG 2366
Score = 43.1 bits (100), Expect = 7e-04
Identities = 131/649 (20%), Positives = 210/649 (32%), Gaps = 108/649 (16%)
Query: 2 SDSGSYGQSGGEQ-QSYSTYGNPGSQGYGQASQS----YSGYGQTTDSSYGQNYSGYSSY 56
S ++ Q+G + +S ST YGQ ++ +SG+GQ+T G +G
Sbjct: 1365 SQEQTHSQAGSQHGESESTVHERHETTYGQTGEATGHGHSGHGQSTQR--GSRTTGRRGS 1422
Query: 57 GQSYSQSYGGYENQKQSSYSQQPYNNQGQQQNMESSGSQGGRAPS----YDQPDYGQQDS 112
G S S +++ S S +P Q Q+Q +GSQ G + S +GQ
Sbjct: 1423 GHSESS-----DSEVHSGGSHRP---QSQEQTHGQAGSQHGESGSTVHGRHGTTHGQTGD 1474
Query: 113 YDQQSGYDQHQGSYDEQSNYDQQHDSYSQNQQSYHSQRENYSHHTQDDRRDVSRYGE--- 169
+ + Y + + S ++ +S++ S +++H + S++GE
Sbjct: 1475 TTRHAHYHHGKSTQRGSSTTGRRGSGHSESSDSEVHSGGSHTHSGHTHGQSGSQHGESES 1534
Query: 170 ---DNRGYGGSQGGGRGRGGYDKDGRGPMTGSSGGDRGGFKNFGGHRDYGPRTDADSESD 226
D Q G R Y + TGS R + TD++ S
Sbjct: 1535 IIHDRHRITHGQTGDTTRHSYSGHEQTTQTGSRTTGR-------QRTSHSESTDSEVHSG 1587
Query: 227 NSDNNTIFVQGLGEGVSTDQVGEF---------FKQIGIIKTNKKTGKPMINLYTDKDTG 277
S G+ S + EF QIG + +G + TG
Sbjct: 1588 GSHRPHSREHTYGQAGSQHEEPEFTVHERHGTTHGQIGDTTGHSHSGHGQSTQRGSRTTG 1647
Query: 278 KPKGEATVSFDDPPSAKAAIDWFDGKEFHG----------NII---------KVSFATRR 318
+ + + S D + + HG +I+ + TR
Sbjct: 1648 RQRSSHSESSDS--EVHSGVSHTHTGHTHGQAGSQHGQSESIVPERHGTTHGQTGDTTRH 1705
Query: 319 PEFMRG-----GGSGGGRRGRG--------GYRG---------RGGFQGRGGDPKSGDWV 356
+ G G GRRG G GY G G + + G+ +S
Sbjct: 1706 AHYHHGLTTQTGSRTTGRRGSGHSEYSDSEGYSGVSHTHSGHTHGQARSQHGESESIVHE 1765
Query: 357 CPNPSCGNMNFARRNSCNQCNEPRPEDSRPSGGDFRGRG-YGGERGYRGRGGRGGDRGGY 415
G R++ + + SR +G G Y G+ G R RG
Sbjct: 1766 RHGTIHGQTGDTTRHAHSGHGQSTQTGSRTTGRRSSGHSEYSDSEGHSGFSQRPHSRGHT 1825
Query: 416 GGDRSGGGYGGDRS---SGGGYSGDRSGGGYGGDRSGGGYGGDRGGGYGGDRGGGYGGDR 472
G ++G +G S G + ++G G +SG G G G R G+
Sbjct: 1826 HG-QAGSQHGESESIVDERHGTTHGQTGDTSGHSQSGHGQSTQSGSSTTGRRRSGHSESS 1884
Query: 473 GGGYGGDRGGYGGDRGGGYGGDRGGYGGDRG----------GYGGDRGGYGGDRGG---Y 519
GG G + R +G G GD +G G
Sbjct: 1885 DSEV--HSGGSHTHSGHTHSQARSQHGESESTVHKRHQTTHGQTGDTTEHGHPSHGQTIQ 1942
Query: 520 GGDRSRGGYGGDRGGGSGYGGDRSGGYGGDRSGGGYGGDRGGGYGGDRG 568
G R+ G RG G D G G + G+ + G + + G
Sbjct: 1943 TGSRTT----GRRGSGHSEYSDSEGPSGVSHTHSGHTHGQAGSHYPESG 1987
Score = 41.6 bits (96), Expect = 0.002
Identities = 51/232 (21%), Positives = 85/232 (36%), Gaps = 37/232 (15%)
Query: 3 DSGSYGQSGGEQQSYSTYGNPG-----------SQGYGQASQSYSGY---------GQTT 42
D+ +GQSG Q + + G S+ + +AS ++SG+ GQ+
Sbjct: 2153 DTTRHGQSGHGQSTQTGSRTTGRQRSSHSESSDSEVHSEASPTHSGHTHSQAGSRHGQSG 2212
Query: 43 DSSYGQNYSGYSSYGQSYSQSYGGYENQKQSSYSQQPYNNQGQQQNMESSGSQGGRAPSY 102
S +G+ + + G + ++ GY Q G ++ +S G + ++
Sbjct: 2213 SSGHGRQGTTHGQTGDTTRHAHYGYGQSTQRGSRTTGRRGSGHSESSDSEVHSWG-SHTH 2271
Query: 103 DQPDYGQQDSYDQQSGYDQH------QGSYDEQSNYDQQHDSYSQNQQSYHSQRENYSHH 156
GQ S +Q G H G + + + H Y Q+ Q+ R + + H
Sbjct: 2272 SGHIQGQAGSQQRQPGSTVHGRLETTHGQTGDTTRHG--HSGYGQSTQT--GSRSSRASH 2327
Query: 157 TQDDRRDVSRYGEDNRGYGGSQGGGRGRGGYDKDGRGPMTGSSGGDRGGFKN 208
Q + R+G GS G Y G GP SGG R N
Sbjct: 2328 FQSHSSERQRHGSSQVWKHGSY--GPAEYDYGHTGYGP----SGGSRKSISN 2373
Score = 38.5 bits (88), Expect = 0.017
Identities = 73/296 (24%), Positives = 93/296 (31%), Gaps = 47/296 (15%)
Query: 288 DDPPSAKAAI---DWFDGKEFHGNIIKVSFATRRPEFMRGGGSGGGRRGRGGYRGRGGFQ 344
+D P K+ W +G+E HG S R GS R GR G G Q
Sbjct: 120 EDTPGHKSGYRHSSWSEGEE-HG----YSSGHSRGTVKCRHGSNSRRLGRQGNLSSSGNQ 174
Query: 345 GRGGDPKSGDWVCPNPSCGNMNFARRNSCN---QCNEPRPEDSRPSGGDFRGRGYGGERG 401
G + C + G + +S + N+ SR SG ++
Sbjct: 175 -EGSQKRYHRSSCGHSWSGGKDRHGSSSVELRERINKSHISPSRESGEEYES-------- 225
Query: 402 YRGRGGRGGDRGGYGGDRSGGGYGGDRS----------------SGGGYSGDRSGGGYGG 445
G G +R G+GG G G S SG G SG RS
Sbjct: 226 --GSGSNSWERKGHGGLSCGLETSGHESNSTQSRIREQKLGSSCSGSGDSGRRSHACGYS 283
Query: 446 DRSGGGYGGDRGGGYGGDRGGGYGGDRGGGYGGDRGGYGGDRGGG--YGGDRGGYGGDRG 503
+ SG G + R GG G G + G G +G G GG G G
Sbjct: 284 NSSGCGRPQNASSSCQSHRFGGQGNQFSYIQSGCQSGIKGGQGHGCVSGGQPSGCGQPES 343
Query: 504 ---GYGGDRGGYGGDRGGY----GGDRSRGGYGGDRGGGSGYGGDRSGGYGGDRSG 552
+ GYG G GG G G G GG +S G G
Sbjct: 344 NPCSQSYSQRGYGARENGQPQNCGGQWRTGSSQSSCCGQYGSGGSQSCSNGQHEYG 399
>gi|57864582 hornerin [Homo sapiens]
Length = 2850
Score = 128 bits (321), Expect = 2e-29
Identities = 157/600 (26%), Positives = 211/600 (35%), Gaps = 72/600 (12%)
Query: 4 SGSYGQSGGEQQSYSTYGNPGSQGYGQASQSYSGYGQTTDSSYGQNYSGYSSYGQSYSQS 63
S YGQ G ST+G GS +S G SS+GQ+ SG SS Y +
Sbjct: 1530 SSGYGQHGSSSGHSSTHGQHGSTSGQSSSCGQHGASSGQSSSHGQHGSG-SSQSSGYGRQ 1588
Query: 64 YGGYENQKQSSYSQQPYNNQGQQQNMESSGSQGGRAPSYDQPDYGQQDSYDQQSGYDQHQ 123
G QS Q + Q + GS GR+ S Q G +S SG+ H+
Sbjct: 1589 GSG---SGQSPGHGQRGSGSRQSPSYGRHGSGSGRSSSSGQHGSGLGES----SGFGHHE 1641
Query: 124 GSYDEQSNYDQQHDSYSQNQQSY--HSQRENYSHHTQ---DDRRDVSRYGEDNRGYGGSQ 178
S + S+Y Q H S S + Y H R S + R SRYG+ G G Q
Sbjct: 1642 SSSGQSSSYSQ-HGSGSGHSSGYGQHGSRSGQSSRGERHGSSSRSSSRYGQ--HGSGSRQ 1698
Query: 179 GGGRGRGGYDKDGRGPMTGSSGGDRGGFKNFGGHRDYGPRTDADSESDN-SDNNTIFVQG 237
G GR G G+ P G G G + G H R+ + ++ S ++++F
Sbjct: 1699 SSGHGRQG-SGSGQSPSRGRHGSGLGHSSSHGQHGSGSGRSSSRGPYESRSGHSSVF--- 1754
Query: 238 LGEGVSTDQVGEFFKQIGIIKTNKKTGKPMINLYTDKDTGKPKGEATVSFDDPPSAKAAI 297
G+ G + G + + G G+++ +FD S+
Sbjct: 1755 ----------GQHESGSGHSSAYSQHGSGSGHFCSQGQHGSTSGQSS-TFDQEGSSTGQS 1803
Query: 298 DWFDGKEFHGNIIKVSFATRRPEFMRGGGSGG----GRRGRG-GYRGRGGFQGRGGDPKS 352
G+ G+ S+ +G GSG GR G G G+ G G G S
Sbjct: 1804 S-SHGQHGSGSSQSSSYG------QQGSGSGQSPSRGRHGSGSGHSSSYGQHGSGSGWSS 1856
Query: 353 GDWVCPNPSCGNMNFARRNSCNQCNEPRPEDSRPSGGDFRGRGYGGERGYRGRGGRGGDR 412
+ S + F S + + + SG +G G RG + G
Sbjct: 1857 SSGRHGSGSGQSSGFGHHESSSWQSSGYTQHGSGSGHSSSYEQHGSRSGQSSRGEQHGSS 1916
Query: 413 GGYGGDRSGGGYGGDRSSGGGYSGDRSGGGYGGDRSGGGYGGDRGGGYGGDRGGGYGGDR 472
G G G +S G G G SG R G G + Y G YG
Sbjct: 1917 SGSSSSYGQHGSGSRQSLGHGQHGSGSGQSPSPSRGRHGSGSGQSSSY-----GPYGS-- 1969
Query: 473 GGGYGGDRGGYGGDRGGGYG-GDRGGYGGDRGGYG--GDRGGYGGDRGGYGGDRSRGGYG 529
G G+ RG Y G G G R G GYG G G+ G +G +
Sbjct: 1970 GSGWSSSRGPYESGSGHSSGLGHRESRSGQSSGYGQHGSSSGHSSTHGQHGSASGQSSSC 2029
Query: 530 GDRGGGSGY---------GGDRSGGYGGDRSGGGYG---GDRGGG------YGGDRGGYG 571
G G SG G +S GYG SG G G RG G YG G G
Sbjct: 2030 GQHGASSGQSSSHGQHGSGSSQSSGYGRQGSGSGQSPGHGQRGSGSRQSPSYGRHGSGSG 2089
Score = 125 bits (315), Expect = 8e-29
Identities = 161/608 (26%), Positives = 206/608 (33%), Gaps = 88/608 (14%)
Query: 4 SGSYGQSGGEQQSYSTYGNPGSQGYGQASQSYSGYGQTTDSSYGQN------YSGYSSYG 57
S YGQ G ST+G GS +S G SS+GQ+ SGY G
Sbjct: 2000 SSGYGQHGSSSGHSSTHGQHGSASGQSSSCGQHGASSGQSSSHGQHGSGSSQSSGYGRQG 2059
Query: 58 QSYSQSYGGYENQKQSSYSQQP-YNNQGQQQNMESSGSQGGRAPSYDQPDYGQQDSYDQQ 116
QS G Q+ S Q P Y G SS Q G + S Q
Sbjct: 2060 SGSGQSPG--HGQRGSGSRQSPSYGRHGSGSGRSSSSGQHGPGLGESSGFGHHESSSGQS 2117
Query: 117 SGYDQHQGSYDEQSNYDQQHDSYSQNQQSYHSQRENYSHHTQDDRRDVSRYGEDNRGYGG 176
S Y QH S Y Q S++ QS +R S + SRYG+ G G
Sbjct: 2118 SSYSQHGSGSGHSSGYGQHG---SRSGQSSRGERHGSSSGSS------SRYGQ--HGSGS 2166
Query: 177 SQGGGRGRGGYDKDGRGPMTGSSGGDRGGFKNFGGHRDYGPRTDADSESDN-SDNNTIFV 235
Q G GR G G P G G G + G H R+ + ++ S ++++F
Sbjct: 2167 RQSSGHGRQG-SGSGHSPSRGRHGSGSGHSSSHGQHGSGSGRSSSRGPYESRSGHSSVF- 2224
Query: 236 QGLGEGVSTDQVGEFFKQIGIIKTNKKTGKPMINLYTDKDTGKPKGEATVSFDDPPSAKA 295
G+ G + G + + G G+++ +FD S+
Sbjct: 2225 ------------GQHESGSGHSSAYSQHGSGSGHFCSQGQHGSTSGQSS-TFDQEGSSTG 2271
Query: 296 AIDWFDGKEFHGNIIKVSFATRRPEFMRGGGSG----GGRRGRG-GYRGRGGFQGRGGDP 350
G+ G+ S+ +G GSG GR G G G+ G G G
Sbjct: 2272 QSS-SHGQHGSGSSQSSSYG------QQGSGSGQSPSRGRHGSGSGHSSSYGQHGSGSGW 2324
Query: 351 KSGDWVCPNPSCGNMNFARRNSCNQCNEPRPEDSRPSGGDFRGRGYGGERGYRGRGGRGG 410
S + S + F S + + SG G G G Y G R G
Sbjct: 2325 SSSSGRHGSGSGQSSGFGHHESSSW---------QSSGYTQHGSGSGHSSSYEQHGSRSG 2375
Query: 411 DRGGYGGDRSGGGYGGDRSSGGGYSGDRSGGGYGGDRSGGGYG-----GDRGGGYGGDRG 465
G+R G G S G SG R G+G SG G G G G G
Sbjct: 2376 QSS--RGERHGSSSGSSSSYGQHGSGSRQSLGHGQHGSGSGQSPSPSRGRHGSGSGQSSS 2433
Query: 466 -GGYGGDRGGGYGGDRGGYGGDRGGGYG-GDRGGYGGDRGGYG--GDRGGYGGDRGGYGG 521
YG G G+ RG Y G G G R G GYG G G+ G +G
Sbjct: 2434 YSPYGS--GSGWSSSRGPYESGSGHSSGLGHRESRSGQSSGYGQHGSSSGHSSTHGQHGS 2491
Query: 522 DRSRGGYGGDRGGGSGY---------GGDRSGGYGGDRSGGGYG---GDRGGG------Y 563
+ G G SG G +S GYG SG G G RG G Y
Sbjct: 2492 TSGQSSSCGQHGASSGQSSSHGQHGSGSSQSSGYGRQGSGSGQSPGHGQRGSGSRQSPSY 2551
Query: 564 GGDRGGYG 571
G G G
Sbjct: 2552 GRHGSGSG 2559
Score = 124 bits (311), Expect = 2e-28
Identities = 162/651 (24%), Positives = 221/651 (33%), Gaps = 107/651 (16%)
Query: 4 SGSYGQSGGEQQSYSTYGNPGSQGYGQASQSYSGYGQTTDSSYGQNYSGYSSYGQSYSQS 63
S YGQ G ST+G GS +S G SS+GQ+ SG S + Q
Sbjct: 594 SSGYGQHGSSSGHSSTHGQHGSTSGQSSSCGQHGATSGQSSSHGQHGSGSSQSSRYGQQG 653
Query: 64 YGGYENQKQSSYSQQPYNNQGQQQNMESSGSQGGRAP----SYDQPDYGQQDSYDQQSGY 119
G ++ + + ++ Q+ SG P S +G + Q SGY
Sbjct: 654 SGSGQSPSRGRHGSDFGHSSSYGQHGSGSGWSSSNGPHGSVSGQSSGFGHKSGSGQSSGY 713
Query: 120 DQHQGSYDEQSNYDQQHDSYSQNQQSYHSQRENYSHHTQDDRRDVSRYGEDNRGYGGSQG 179
QH S Y ++H S++ QS S++ S S YG+ G G Q
Sbjct: 714 SQHGSGSSHSSGY-RKHG--SRSGQSSRSEQHGSSSGLS------SSYGQ--HGSGSHQS 762
Query: 180 GGRGRGGYDKDGRGPMTGSSGGDRGGFKNFGGHRDYGPRTDADSESDNSDNNTIFVQGLG 239
G GR G G P G G + G H G T S + ++ + G G
Sbjct: 763 SGHGRQG-SGSGHSPSRVRHGSSSGHSSSHGQH---GSGTSCSSSCGHYESGSGQASGFG 818
Query: 240 EGVSTDQVGEFFKQIGII--------KTNKKTGKPMINLYTDKDTGKPKGEATVSFDDPP 291
+ S G+ + Q G + +G+ + D +G+
Sbjct: 819 QHESGS--GQGYSQHGSASGHFSSQGRHGSTSGQSSSSGQHDSSSGQSSSYGQHESASHH 876
Query: 292 SAKAAIDWFDGKEFHGNIIKVSFATRRPEFMRGGGSGGGRRGRGGYRGRG-----GFQGR 346
++ + G+ + S + + P + R GSG GR G G G GF +
Sbjct: 877 ASGRGRHGSGSGQSPGHGQRGSGSGQSPSYGR-HGSGSGRSSSSGRHGSGSGQSSGFGHK 935
Query: 347 GGDPKSGDWVCPNPSCGNMNFARRNSCNQCNEPRPEDSRPSGGDFRGRGYGGERG----- 401
+S + G+ + ++ R E S G G G
Sbjct: 936 SSSGQSSGYTQHGSGSGHSSSYEQHGSRSGQSSRSEQHGSSSGSSSSYGQHGSGSRQSLG 995
Query: 402 --------------YRGRGGRG-GDRGGYGGDRSGGGY---------GGDRSSGGGYSGD 437
RGR G G G YG RSG G+ G SSG G+
Sbjct: 996 HGQHGSGSGQSPSPSRGRHGSGSGQSSSYGPYRSGSGWSSSRGPYESGSGHSSGLGHRES 1055
Query: 438 RSG--GGYGGDRSGGGYGGDRG------------GGYGGDRG-------GGYGGDRGGGY 476
RSG GYG S G+ G G +G G G G + GY
Sbjct: 1056 RSGQSSGYGQHGSSSGHSSTHGQHGSTSGQSSSCGQHGASSGQSSSHGQHGSGSSQSSGY 1115
Query: 477 GGDRGGYG-----GDRGGG------YGGDRGGYGGDRGGYGGDRGGYGGDRGGYGGDRSR 525
G G G G RG G YG R G G R G G G+ G+G S
Sbjct: 1116 GRQGSGSGQSPGHGQRGSGSRQSPSYG--RHGSGSGRSSSSGQHGSGLGESSGFGHHESS 1173
Query: 526 GGYG---GDRGGGSGYGGDRSGGYG--GDRSGGGYGGDRGGGYGGDRGGYG 571
G G GSG+ S GYG G RSG G+R G G YG
Sbjct: 1174 SGQSSSYSQHGSGSGH----SSGYGQHGSRSGQSSRGERHGSSSGSSSHYG 1220
Score = 122 bits (307), Expect = 7e-28
Identities = 160/592 (27%), Positives = 213/592 (35%), Gaps = 51/592 (8%)
Query: 4 SGSYGQSGGEQQSYSTYGNPGSQGYGQA---SQSYSGYGQ-----TTDSSYGQNYSGYSS 55
S SYG+ + S G GS G GQ+ Q SG GQ T S GQ+ SG+S
Sbjct: 176 SSSYGEQNSDSHQSSGRGQCGS-GSGQSPNYGQHGSGSGQSSSNDTHGSGSGQS-SGFSQ 233
Query: 56 YGQSYSQSYGGYENQKQSSYSQQPYNNQGQQQNMESSGSQGGRAPSYDQPDYGQQDSYDQ 115
+ S QS GY S Y G + S G + R+ S YGQ S +
Sbjct: 234 HKSSSGQS-SGYSQHGSGSGHSSGYGQHGSRSGQSSRGER-HRSSSGSSSSYGQHGSGSR 291
Query: 116 QSGYDQHQGSYDEQSNYDQQHDSYSQNQQSYHSQRENYSHHTQDDRRDVSRYGEDNRGYG 175
QS QGS QS +H S S + S H Q + S ++ S G+ + G+G
Sbjct: 292 QSLGHGRQGSGSRQSPSHVRHGSGSGHSSS-HGQHGSGSSYSYSRGHYESGSGQTS-GFG 349
Query: 176 GSQGGGRGRGGYDKDGRGPMTGSSGGDRGGFKNFGGHRDYGPRTDADSESDNSDNNTIFV 235
+ G GY K G G SS G G G + + +S ++ +
Sbjct: 350 QHESGSGQSSGYSKHGSGSGHSSSQGQHGSTS--------GQASSSGQHGSSSRQSSSYG 401
Query: 236 QGLGEGVSTDQVGEFFKQIGIIKTNKKTGKPMINLYTDKDTGKPKGEATVSFDDPPSAKA 295
Q + G+ G + + G + G G ++ S P
Sbjct: 402 QHESASRHSSGRGQHSSGSGQSPGHGQRGSGSGQSPSSGQHGTGFGRSSSS---GPYVSG 458
Query: 296 AIDWFDGKEFHGNIIKVSFATRRPEFMRGGGSGGGRRG-RGGYRGRGGFQGRGGDPKSGD 354
+ + G H + + S + G SG G+ G R G RG QG S
Sbjct: 459 S-GYSSGFGHHESSSEHSSGYTQHGSGSGHSSGHGQHGSRSGQSSRGERQGSSAGSSSSY 517
Query: 355 WVCPNPSCGNMNFARRNSCNQCNEPRPEDSRPSGGDFRGRGYGGERGYRGRGGRGGDRGG 414
+ S ++ +R S P P R G + Y G GY GR RG
Sbjct: 518 GQHGSGSRQSLGHSRHGS-GSGQSPSPSRGRHESGSRQSSSY-GPHGY--GSGRSSSRGP 573
Query: 415 YGGDRSGGGYGGDRSSGGGYSGDRSG--GGYGGDRSGGGYGGDRG--GGYGGDRG--GGY 468
Y SG G+ SSG G+ RSG GYG S G+ G G G G +
Sbjct: 574 Y---ESGSGH----SSGLGHQESRSGQSSGYGQHGSSSGHSSTHGQHGSTSGQSSSCGQH 626
Query: 469 GGDRGGGYGGDRGGYGGDRGGGYG--GDRGGYGGDRGGYGGDRG---GYGGDRGGYGGDR 523
G G + G G + YG G G RG +G D G YG G G
Sbjct: 627 GATSGQSSSHGQHGSGSSQSSRYGQQGSGSGQSPSRGRHGSDFGHSSSYGQHGSGSGWSS 686
Query: 524 SRGGYGGDRGGGSGYGGDRSGGYGGDRSGGGYGGDRGGGY--GGDRGGYGGK 573
S G +G G SG+G G S G G GY G R G +
Sbjct: 687 SNGPHGSVSGQSSGFGHKSGSGQSSGYSQHGSGSSHSSGYRKHGSRSGQSSR 738
Score = 122 bits (306), Expect = 9e-28
Identities = 166/611 (27%), Positives = 214/611 (35%), Gaps = 62/611 (10%)
Query: 4 SGSYGQSGGEQQSYSTYGNPGSQGYGQASQSYSGYGQTTDSSYGQNYSG---YSSYGQ-- 58
S S+GQ G S YG GS G G SYG++ SG SS GQ
Sbjct: 2039 SSSHGQHGSGSSQSSGYGRQGSGSGQSPGHGQRGSGSRQSPSYGRHGSGSGRSSSSGQHG 2098
Query: 59 ---SYSQSYGGYENQ--KQSSYSQ--------QPYNNQGQQQNMESSGSQGGRAPSYDQP 105
S +G +E+ + SSYSQ Y G + S G + G + S
Sbjct: 2099 PGLGESSGFGHHESSSGQSSSYSQHGSGSGHSSGYGQHGSRSGQSSRGERHG-SSSGSSS 2157
Query: 106 DYGQQDSYDQQSGYDQHQGSYDEQSNYDQQHDSYSQNQQSYHSQRENYSHHTQDDRRDVS 165
YGQ S +QS QGS S +H S S + S H Q + S + S
Sbjct: 2158 RYGQHGSGSRQSSGHGRQGSGSGHSPSRGRHGSGSGHSSS-HGQHGSGSGRSSSRGPYES 2216
Query: 166 RYGEDNRGYGGSQGGGRGRGGYDKDGRGPMTGSSGGDRGGFKNFGGHRDY-GPRTDADSE 224
R G + +G + G Y + G G S G G D G T S
Sbjct: 2217 RSGHSS-VFGQHESGSGHSSAYSQHGSGSGHFCSQGQHGSTSGQSSTFDQEGSSTGQSSS 2275
Query: 225 -----SDNSDNNTIFVQGLGEGVSTDQVGEFFKQIGIIKTNKKTGKPMINLYTDKDTGKP 279
S +S +++ QG G G S + G G + + G + G
Sbjct: 2276 HGQHGSGSSQSSSYGQQGSGSGQSPSR-GRHGSGSGHSSSYGQHGSGSGWSSSSGRHGSG 2334
Query: 280 KGEATVSFDDPPSAKAAIDWFDGKEFHGNIIKV-SFATRRPEFMRG--GGSGGGRRGRGG 336
G+++ S+ + + G+ +R + RG GS G G
Sbjct: 2335 SGQSSGFGHHESSSWQSSGYTQHGSGSGHSSSYEQHGSRSGQSSRGERHGSSSGSSSSYG 2394
Query: 337 YRGRGGFQGRG-GDPKSGDWVCPNPSCGNMNFARRNSCNQCNEPRPEDSRPSGGDFRG-- 393
G G Q G G SG P+PS G + Q + P S RG
Sbjct: 2395 QHGSGSRQSLGHGQHGSGSGQSPSPSRGR----HGSGSGQSSSYSPYGSGSGWSSSRGPY 2450
Query: 394 -RGYGGERGYRGRGGRGGDRGGYGGDRSGGGYGGDRSSGGGYSGDRSGGGYGGDRSG--- 449
G G G R R G GYG S G+ G SG S G G SG
Sbjct: 2451 ESGSGHSSGLGHRESRSGQSSGYGQHGSSSGHSSTHGQHGSTSGQSSSCGQHGASSGQSS 2510
Query: 450 ----GGYGGDRGGGYGGDRGGGYGGDRGGGYGGDRGGYGGDRGGGYGGDRGGYGGDRGGY 505
G G + GY G +G G G G G + G G + YG R G G R
Sbjct: 2511 SHGQHGSGSSQSSGY-GRQGSGSGQSPGHG----QRGSGSRQSPSYG--RHGSGSGRSSS 2563
Query: 506 GGDRGGYGGDRGGYGGDRSRGGYG---GDRGGGSGYGGDRSGGYG--GDRSGGGYGGDRG 560
G G G+ G+G S G G GSG+ S GYG G RSG G+R
Sbjct: 2564 SGQHGSGLGESSGFGHHESSSGQSSSYSQHGSGSGH----SSGYGQHGSRSGQSSRGERH 2619
Query: 561 GGYGGDRGGYG 571
G G YG
Sbjct: 2620 GSSSGSSSHYG 2630
Score = 122 bits (305), Expect = 1e-27
Identities = 166/611 (27%), Positives = 213/611 (34%), Gaps = 62/611 (10%)
Query: 4 SGSYGQSGGEQQSYSTYGNPGSQGYGQASQSYSGYGQTTDSSYGQNYSGY---SSYGQ-- 58
S S+GQ G S YG GS G G SYG++ SG SS GQ
Sbjct: 1569 SSSHGQHGSGSSQSSGYGRQGSGSGQSPGHGQRGSGSRQSPSYGRHGSGSGRSSSSGQHG 1628
Query: 59 ---SYSQSYGGYENQ--KQSSYSQQP--------YNNQGQQQNMESSGSQGGRAPSYDQP 105
S +G +E+ + SSYSQ Y G + S G + G + S
Sbjct: 1629 SGLGESSGFGHHESSSGQSSSYSQHGSGSGHSSGYGQHGSRSGQSSRGERHGSS-SRSSS 1687
Query: 106 DYGQQDSYDQQSGYDQHQGSYDEQSNYDQQHDSYSQNQQSYHSQRENYSHHTQDDRRDVS 165
YGQ S +QS QGS QS +H S S H Q + S + S
Sbjct: 1688 RYGQHGSGSRQSSGHGRQGSGSGQSPSRGRHGS-GLGHSSSHGQHGSGSGRSSSRGPYES 1746
Query: 166 RYGEDNRGYGGSQGGGRGRGGYDKDGRGPMTGSSGGDRGGFKNFGGHRDY-GPRTDADSE 224
R G + +G + G Y + G G S G G D G T S
Sbjct: 1747 RSGHSSV-FGQHESGSGHSSAYSQHGSGSGHFCSQGQHGSTSGQSSTFDQEGSSTGQSSS 1805
Query: 225 -----SDNSDNNTIFVQGLGEGVSTDQVGEFFKQIGIIKTNKKTGKPMINLYTDKDTGKP 279
S +S +++ QG G G S + G G + + G + G
Sbjct: 1806 HGQHGSGSSQSSSYGQQGSGSGQSPSR-GRHGSGSGHSSSYGQHGSGSGWSSSSGRHGSG 1864
Query: 280 KGEATVSFDDPPSAKAAIDWFDGKEFHGNIIKVS-FATRRPEFMRGG--GSGGGRRGRGG 336
G+++ S+ + + G+ +R + RG GS G G
Sbjct: 1865 SGQSSGFGHHESSSWQSSGYTQHGSGSGHSSSYEQHGSRSGQSSRGEQHGSSSGSSSSYG 1924
Query: 337 YRGRGGFQGRG-GDPKSGDWVCPNPSCGNMNFARRNSCNQCNEPRPEDSRPSGGDFRG-- 393
G G Q G G SG P+PS G + Q + P S RG
Sbjct: 1925 QHGSGSRQSLGHGQHGSGSGQSPSPSRGRHG----SGSGQSSSYGPYGSGSGWSSSRGPY 1980
Query: 394 -RGYGGERGYRGRGGRGGDRGGYGGDRSGGGYGGDRSSGGGYSGDRSGGGYGGDRSG--- 449
G G G R R G GYG S G+ G SG S G G SG
Sbjct: 1981 ESGSGHSSGLGHRESRSGQSSGYGQHGSSSGHSSTHGQHGSASGQSSSCGQHGASSGQSS 2040
Query: 450 ----GGYGGDRGGGYGGDRGGGYGGDRGGGYGGDRGGYGGDRGGGYGGDRGGYGGDRGGY 505
G G + GY G +G G G G G + G G + YG R G G R
Sbjct: 2041 SHGQHGSGSSQSSGY-GRQGSGSGQSPGHG----QRGSGSRQSPSYG--RHGSGSGRSSS 2093
Query: 506 GGDRGGYGGDRGGYGGDRSRGGYG---GDRGGGSGYGGDRSGGYG--GDRSGGGYGGDRG 560
G G G+ G+G S G G GSG+ S GYG G RSG G+R
Sbjct: 2094 SGQHGPGLGESSGFGHHESSSGQSSSYSQHGSGSGH----SSGYGQHGSRSGQSSRGERH 2149
Query: 561 GGYGGDRGGYG 571
G G YG
Sbjct: 2150 GSSSGSSSRYG 2160
Score = 119 bits (297), Expect = 1e-26
Identities = 166/634 (26%), Positives = 216/634 (34%), Gaps = 122/634 (19%)
Query: 2 SDSGSYGQSGGEQQSYSTYGNPGSQGYGQASQSYSGYGQTTDSSYGQN--YSGYSSYGQS 59
S SG +G GE S +G+ S +S S G G S YGQ+ SG SS G+
Sbjct: 1152 SSSGQHGSGLGES---SGFGHHESSSGQSSSYSQHGSGSGHSSGYGQHGSRSGQSSRGER 1208
Query: 60 YSQSYGGYEN-------QKQSSYSQQPYNNQGQQQNMESSGSQGGRAPSYDQPDYGQQDS 112
+ S G + +QSS + + G + GS G + S+ Q G S
Sbjct: 1209 HGSSSGSSSHYGQHGSGSRQSSGHGRQGSGSGHSPSRGRHGSGLGHSSSHGQHGSGSGRS 1268
Query: 113 -----YDQQSGYDQHQGSYDEQSNYDQQHDSYSQNQQSYHSQRENYSHHTQDDRRDV--- 164
Y+ +SG+ G ++ S + + + + SQ ++ S Q D
Sbjct: 1269 SSRGPYESRSGHSSVFGQHESGSGHSSAYSQHGSGSGHFCSQGQHGSTSGQSSTFDQEGS 1328
Query: 165 -----SRYGEDNRGYGGSQGGGRGRGGYDKDGRGPMTGSSGGDRGGFKNFGGHRDYGPRT 219
S YG +RG G SQ G GR G G+ P G G G ++G H G +
Sbjct: 1329 STGQSSSYG--HRGSGSSQSSGYGRHGAGS-GQSPSRGRHGSGSGHSSSYGQH---GSGS 1382
Query: 220 DADSESDNSDNNTIFVQGLGEGVSTDQVGEFFKQIGIIKTNKKTGKPMINLYTDKDTGKP 279
S S + + G G S+ Q G +G + Y
Sbjct: 1383 GWSSSSGRHGSGSGQSSGFGHHESSSWQSSGCTQHG-------SGSGHSSSY-------- 1427
Query: 280 KGEATVSFDDPPSAKAAIDWFDGKEFHGNIIKVSFATRRPEFMRGG--GSGGGRRGRGGY 337
E HG+ R + RG GS G G
Sbjct: 1428 ------------------------EQHGS--------RSGQSSRGERHGSSSGSSSSYGQ 1455
Query: 338 RGRGGFQGRG-GDPKSGDWVCPNPSCGNMNFARRNSCNQCNEPRPEDSRPSGGDFRG--- 393
G G Q G G SG P+PS G + Q + P S RG
Sbjct: 1456 HGSGSRQSLGHGQHGSGSGQSPSPSRGRHG----SGSGQSSSYSPYGSGSGWSSSRGPYE 1511
Query: 394 RGYGGERGYRGRGGRGGDRGGYGGDRSGGGYGGDRSSGGGYSGDRSGGGYGGDRSG---- 449
G G R R G GYG S G+ G SG S G G SG
Sbjct: 1512 SGSSHSSGLGHRESRSGQSSGYGQHGSSSGHSSTHGQHGSTSGQSSSCGQHGASSGQSSS 1571
Query: 450 ---GGYGGDRGGGYGGDRGGGYG-----GDRGGG------YGGDRGGYG-----GDRGGG 490
G G + GY G +G G G G RG G YG G G G G G
Sbjct: 1572 HGQHGSGSSQSSGY-GRQGSGSGQSPGHGQRGSGSRQSPSYGRHGSGSGRSSSSGQHGSG 1630
Query: 491 YGGDRGGYGGDRGGYG-----GDRGGYGGDRGGYGGDRSRGGYG--GDRGGGSGYGGDRS 543
G+ G+G G G G GYG SR G G+R G S R
Sbjct: 1631 L-GESSGFGHHESSSGQSSSYSQHGSGSGHSSGYGQHGSRSGQSSRGERHGSSSRSSSRY 1689
Query: 544 GGYG-GDRSGGGYGGD-RGGGYGGDRGGYGGKMG 575
G +G G R G+G G G RG +G +G
Sbjct: 1690 GQHGSGSRQSSGHGRQGSGSGQSPSRGRHGSGLG 1723
Score = 117 bits (292), Expect = 4e-26
Identities = 149/626 (23%), Positives = 213/626 (34%), Gaps = 88/626 (14%)
Query: 2 SDSGSYGQSGGEQQSYSTYGNPGSQGY---GQASQSYSGYGQTTDSSYGQNYSGYSSYGQ 58
S G Y G+ + + + QGY G AS +S G+ +S + SG
Sbjct: 802 SSCGHYESGSGQASGFGQHESGSGQGYSQHGSASGHFSSQGRHGSTSGQSSSSGQHDSSS 861
Query: 59 SYSQSYGGYENQKQSSYSQQPY-NNQGQQQNMESSGSQGGRAPSY--------------- 102
S SYG +E+ + + + + GQ GS G++PSY
Sbjct: 862 GQSSSYGQHESASHHASGRGRHGSGSGQSPGHGQRGSGSGQSPSYGRHGSGSGRSSSSGR 921
Query: 103 ------DQPDYGQQDSYDQQSGYDQHQGSYDEQSNYDQQ-----HDSYSQNQQSYHSQRE 151
+G + S Q SGY QH S+Y+Q S S+ S
Sbjct: 922 HGSGSGQSSGFGHKSSSGQSSGYTQHGSGSGHSSSYEQHGSRSGQSSRSEQHGSSSGSSS 981
Query: 152 NYSHHTQDDRRDVSRYGEDNRGYGGSQGGGRGR---GGYDKDGRGPMTGSSG--GDRGGF 206
+Y H R+ + +G+ G G S RGR G GP SG RG +
Sbjct: 982 SYGQHGSGSRQSLG-HGQHGSGSGQSPSPSRGRHGSGSGQSSSYGPYRSGSGWSSSRGPY 1040
Query: 207 KNFGGHRD-YGPRTDADSESDNSDNNTIFVQGLGEGVSTDQVGEFFKQIGIIKTNKKTGK 265
++ GH G R +S G G+ S+ Q G +G+
Sbjct: 1041 ESGSGHSSGLGHRESRSGQS----------SGYGQHGSSSGHSSTHGQHG-----STSGQ 1085
Query: 266 PMINLYTDKDTGKPKGEATVSFDDPPSAKAAIDWFDGKEFHGNIIKVSFATRRPEFMRGG 325
+G+ S+ + G+ + S + + P + R
Sbjct: 1086 SSSCGQHGASSGQSSSHGQHGSGSSQSSGYGRQGSGSGQSPGHGQRGSGSRQSPSYGR-H 1144
Query: 326 GSGGGRRGRGGYRGRGGFQGRG-GDPKSGDWVCPNPSCGNMNFARRNSCNQCNEPRPEDS 384
GSG GR G G G + G G +S S + ++++ S + + +
Sbjct: 1145 GSGSGRSSSSGQHGSGLGESSGFGHHESS-------SGQSSSYSQHGSGSGHSSGYGQHG 1197
Query: 385 RPSGGDFRGRGYGGERGYRGRGGR--GGDRGGYGGDRSGGGYGGDRSSGGGYSGDRSGGG 442
SG RG +G G G+ G R G R G G G S G SG
Sbjct: 1198 SRSGQSSRGERHGSSSGSSSHYGQHGSGSRQSSGHGRQGSGSGHSPSRGRHGSGLGHSSS 1257
Query: 443 YGGDRSGGGYGGDRG-----GGYGG-----DRGGGYG---GDRGGGYG-----GDRGGYG 484
+G SG G RG G+ + G G+ G G G G G
Sbjct: 1258 HGQHGSGSGRSSSRGPYESRSGHSSVFGQHESGSGHSSAYSQHGSGSGHFCSQGQHGSTS 1317
Query: 485 G-----DRGGGYGGDRGGYGGDRGGYGGDRGGYGGDRGGYGGDRSRGGYGGDRGGGSGYG 539
G D+ G G Y G RG GYG G G SRG +G G S YG
Sbjct: 1318 GQSSTFDQEGSSTGQSSSY-GHRGSGSSQSSGYGRHGAGSGQSPSRGRHGSGSGHSSSYG 1376
Query: 540 GDRSG-GYGGDRSGGGYGGDRGGGYG 564
SG G+ G G + G+G
Sbjct: 1377 QHGSGSGWSSSSGRHGSGSGQSSGFG 1402
Score = 116 bits (290), Expect = 7e-26
Identities = 149/586 (25%), Positives = 191/586 (32%), Gaps = 73/586 (12%)
Query: 4 SGSYGQSGGEQQSYSTYGNPGSQGYGQASQSYSGYGQ----TTDSSYGQNY----SGYSS 55
SGS SG Q S+ + G +G S SGYGQ + SS G+ + SS
Sbjct: 223 SGSGQSSGFSQHKSSSGQSSGYSQHGSGSGHSSGYGQHGSRSGQSSRGERHRSSSGSSSS 282
Query: 56 YGQSYSQSYGGYENQKQSSYSQQ--PYNNQGQQQNMESSGSQGGRAPSYDQPDYGQQDSY 113
YGQ S S + +Q S S+Q + G SS Q G SY +
Sbjct: 283 YGQHGSGSRQSLGHGRQGSGSRQSPSHVRHGSGSGHSSSHGQHGSGSSYSYSRGHYESGS 342
Query: 114 DQQSGYDQHQGSYDEQSNYDQQHD----SYSQNQQSYHSQRENYSHHTQDDRRDVSRYGE 169
Q SG+ QH+ + S Y + S SQ Q S + + S R S YG+
Sbjct: 343 GQTSGFGQHESGSGQSSGYSKHGSGSGHSSSQGQHGSTSGQASSSGQHGSSSRQSSSYGQ 402
Query: 170 DNRGYGGSQGGGRGRGGYDKDGRGPMTGSSGGDRGGFKNFGGHRDYGPRTDADSESDNSD 229
S G G+ G G+ P G G G + G H G S S
Sbjct: 403 HESASRHSSGRGQHSSG---SGQSPGHGQRGSGSGQSPSSGQH---GTGFGRSSSSGPYV 456
Query: 230 NNTIFVQGLGEGVSTDQVGEFFKQIGIIKTNKKTGKPMINLYTDKDTGKPKGEATVSFDD 289
+ + + G G S+ + + Q G +G G
Sbjct: 457 SGSGYSSGFGHHESSSEHSSGYTQHG------------------SGSGHSSGHGQ----- 493
Query: 290 PPSAKAAIDWFDGKEFHGNIIKVSFATRRPEFMRGGGSGGGRRGRGGYRGRGGFQGRGGD 349
HG+ S R G S G+ G G + G R G
Sbjct: 494 ----------------HGSRSGQSSRGERQGSSAGSSSSYGQHGSGSRQSLG--HSRHG- 534
Query: 350 PKSGDWVCPNPSCGNMNFARRNSCNQCNEPRPEDSRPSGGDFRGRGYGGERGYRGRGGRG 409
SG P+PS G R S + S G + G G G + R
Sbjct: 535 --SGSGQSPSPSRGRHESGSRQSSSYGPHGYGSGRSSSRGPYES-GSGHSSGLGHQESRS 591
Query: 410 GDRGGYGGDRSGGGYGGDRSSGGGYSGDRSGGGYGGDRSG--GGYGGDRGGGYGGDRGGG 467
G GYG S G+ G SG S G G SG +G G R G
Sbjct: 592 GQSSGYGQHGSSSGHSSTHGQHGSTSGQSSSCGQHGATSGQSSSHGQHGSGSSQSSRYGQ 651
Query: 468 YGGDRGGGYGGDRGGYGGDRGGGYGGDRGGYGGDRGGYGGDRGGYGGDRGGYGGDRSRGG 527
G G G RG +G D G + G G G G G G+G G
Sbjct: 652 QGS--GSGQSPSRGRHGSDFGHSSSYGQHGSGSGWSSSNGPHGSVSGQSSGFGHKSGSGQ 709
Query: 528 YGGDRGGGSGYGGDRSGGY--GGDRSGGGYGGDRGGGYGGDRGGYG 571
G GS G S GY G RSG ++ G G YG
Sbjct: 710 SSGYSQHGS--GSSHSSGYRKHGSRSGQSSRSEQHGSSSGLSSSYG 753
Score = 115 bits (288), Expect = 1e-25
Identities = 157/643 (24%), Positives = 210/643 (32%), Gaps = 80/643 (12%)
Query: 4 SGSYGQSGGEQQSYSTYGNPGSQGYGQASQSYS-GYGQTTDSSYGQNYSG-YSSYGQSYS 61
S Y Q G S Y GS+ GQ+S+S G SSYGQ+ SG + S G
Sbjct: 710 SSGYSQHGSGSSHSSGYRKHGSRS-GQSSRSEQHGSSSGLSSSYGQHGSGSHQSSGHGRQ 768
Query: 62 QSYGGYENQK----QSSYSQQPYNNQGQQQNMESS----GSQGGRAPSYDQPDYGQQDSY 113
S G+ + SS + G + SS S G+A + Q + G Y
Sbjct: 769 GSGSGHSPSRVRHGSSSGHSSSHGQHGSGTSCSSSCGHYESGSGQASGFGQHESGSGQGY 828
Query: 114 DQQSGYDQH------QGSYDEQSNYDQQHDSYSQNQQSYHSQRENYSHHTQDDRRDVSRY 167
Q H GS QS+ QHDS S Q S + Q E+ SHH R S
Sbjct: 829 SQHGSASGHFSSQGRHGSTSGQSSSSGQHDS-SSGQSSSYGQHESASHHASGRGRHGSGS 887
Query: 168 GED----NRGYGGSQGGGRGRGGYDKDGRGPMTGSSGGDRGGFKNFGGHRDYGPRTDADS 223
G+ RG G Q GR G GR +G G G FG G +
Sbjct: 888 GQSPGHGQRGSGSGQSPSYGRHG-SGSGRSSSSGRHGSGSGQSSGFGHKSSSGQSSGYTQ 946
Query: 224 ESDNSDNNTIFVQGLGEGVSTDQVGEFFKQIGIIKTNKKTGKPMINLYTDKDTGKPKGEA 283
S +++ + Q + + + G + + G G G++
Sbjct: 947 HGSGSGHSSSYEQHGSRSGQSSRSEQHGSSSGSSSSYGQHGSGSRQSLGHGQHGSGSGQS 1006
Query: 284 TVSFDDPPSAKAAIDWFDGKEFHGNIIKVSFATRRPEFMRGGGSGGGRRGRGGYRGRGGF 343
P + + +++ R + G G G R G+
Sbjct: 1007 P----SPSRGRHGSGSGQSSSYGPYRSGSGWSSSRGPYESGSGHSSGLGHRESRSGQSSG 1062
Query: 344 QGRGGDPKS--------GDWVCPNPSCGNMNFARRNSCNQCNEPRPEDSRPSGGDFRGRG 395
G+ G G + SCG + S + + S+ SG +G G
Sbjct: 1063 YGQHGSSSGHSSTHGQHGSTSGQSSSCGQHGASSGQSSSH-GQHGSGSSQSSGYGRQGSG 1121
Query: 396 YG-----GERGYR-------GRGGRG--------------GDRGGYGGDRSGGGYGGDRS 429
G G+RG GR G G G+ G+G S G S
Sbjct: 1122 SGQSPGHGQRGSGSRQSPSYGRHGSGSGRSSSSGQHGSGLGESSGFGHHESSSGQSSSYS 1181
Query: 430 SGGGYSGDRSGGGYGGDRSGGGYGGDRGGGYGGDRGGGYGGDRGGGYGGDRGGYGGDRGG 489
G SG SG G G RSG G+R G G + G G G G G
Sbjct: 1182 QHGSGSGHSSGYGQHGSRSGQSSRGERHGSSSG--SSSHYGQHGSGSRQSSGHGRQGSGS 1239
Query: 490 GYGGDRGGYGGDRG-----GYGGDRGGYGGDRGGYGGDRSRGGYGGDRGGGSGYG----- 539
G+ RG +G G G G G RG Y G GSG+
Sbjct: 1240 GHSPSRGRHGSGLGHSSSHGQHGSGSGRSSSRGPYESRSGHSSVFGQHESGSGHSSAYSQ 1299
Query: 540 -GDRSG-----GYGGDRSGGGYGGDRGGGYGGDRGGYGGKMGG 576
G SG G G SG D+ G G YG + G
Sbjct: 1300 HGSGSGHFCSQGQHGSTSGQSSTFDQEGSSTGQSSSYGHRGSG 1342
Score = 115 bits (287), Expect = 1e-25
Identities = 161/609 (26%), Positives = 213/609 (34%), Gaps = 83/609 (13%)
Query: 30 QASQSYSGYGQTTDSSYGQNYSGYSSYGQ-------SYSQSYGGYENQKQSSYSQQP--Y 80
++S S+S + + SY +N G G S+ + + G N SYS Q Y
Sbjct: 124 ESSFSHSSWSAGENDSYSRNVRGSLKPGTESISRRLSFQRDFSGQHN----SYSGQSSSY 179
Query: 81 NNQGQQQNMESSGSQGGRAPSYDQPDYGQQDSYDQQSGYDQHQGSYDEQSNYDQQHDSYS 140
Q + S Q G S P+YGQ S QS + GS QS+ QH S S
Sbjct: 180 GEQNSDSHQSSGRGQCGSG-SGQSPNYGQHGSGSGQSSSNDTHGSGSGQSSGFSQHKS-S 237
Query: 141 QNQQSYHSQRENYSHHTQDDRRDVSRYGEDNRG------------YGGSQGGGRGRGGYD 188
Q S +SQ + S H+ + SR G+ +RG YG G R G+
Sbjct: 238 SGQSSGYSQHGSGSGHSSGYGQHGSRSGQSSRGERHRSSSGSSSSYGQHGSGSRQSLGHG 297
Query: 189 KDGRGPMTGSSGGDRG-GFKNFGGHRDYGPRTDADSESDNSDNNTIFVQGLGEGVSTDQV 247
+ G G S G G + H +G S S S + + G G+ T
Sbjct: 298 RQGSGSRQSPSHVRHGSGSGHSSSHGQHG------SGSSYSYSRGHYESGSGQ---TSGF 348
Query: 248 GEFFKQIGIIKTNKKTGKPMINLYTDKDTGKPKGEATVSFDDPPSAKAAIDWFDGKEFHG 307
G+ G K G + + G G+A+ S S++ + + H
Sbjct: 349 GQHESGSGQSSGYSKHGSGSGHSSSQGQHGSTSGQASSSGQHGSSSRQSSSYGQ----HE 404
Query: 308 NIIKVSFATRRPEFMRGGGSGGGRRGRG-GYRGRGGFQGRGGDPKSGDWVCPNPSCGNMN 366
+ + S + G G G+RG G G G G G S + S +
Sbjct: 405 SASRHSSGRGQHSSGSGQSPGHGQRGSGSGQSPSSGQHGTGFGRSSSSGPYVSGSGYSSG 464
Query: 367 FARRNSCNQCNEPRPEDSRPSGGDFRGRGYGGERGYRGRGGRGGDRGG----YG----GD 418
F S ++ + + SG +G G RG R G G YG G
Sbjct: 465 FGHHESSSEHSSGYTQHGSGSGHSSGHGQHGSRSGQSSRGERQGSSAGSSSSYGQHGSGS 524
Query: 419 R---------SGGGYGGDRSSGGGYSGDRSGGGYGGDRSGGGYGGDRG---GGYGGDRGG 466
R SG G S G SG R YG G G RG G G G
Sbjct: 525 RQSLGHSRHGSGSGQSPSPSRGRHESGSRQSSSYGPHGYGSGRSSSRGPYESGSGHSSGL 584
Query: 467 GYGGDRGG---GYG--GDRGGYG---GDRGGGYG-----GDRGGYGGDRGGYGGDRGG-- 511
G+ R G GYG G G+ G G G G G G +G G
Sbjct: 585 GHQESRSGQSSGYGQHGSSSGHSSTHGQHGSTSGQSSSCGQHGATSGQSSSHGQHGSGSS 644
Query: 512 ----YGGDRGGYGGDRSRGGYGGDRGGGSGYGGDRSGGYGGDRSGGGYGGDRGGGYG-GD 566
YG G G SRG +G D G S YG SG G S G +G G G G
Sbjct: 645 QSSRYGQQGSGSGQSPSRGRHGSDFGHSSSYGQHGSGS-GWSSSNGPHGSVSGQSSGFGH 703
Query: 567 RGGYGGKMG 575
+ G G G
Sbjct: 704 KSGSGQSSG 712
Score = 110 bits (275), Expect = 4e-24
Identities = 153/593 (25%), Positives = 197/593 (33%), Gaps = 74/593 (12%)
Query: 7 YGQSGGEQQSYSTYGNPGSQGYGQASQSYSGYGQTTDSSYGQNYSGYSSYGQSYSQSYGG 66
+G S G SY +G+ Q G Q SG GQ+ S G++ SG S SY
Sbjct: 1443 HGSSSGSSSSYGQHGSGSRQSLGHG-QHGSGSGQSPSPSRGRHGSG-----SGQSSSYSP 1496
Query: 67 YENQKQSSYSQQPYNNQGQQQNMESSGSQGGRAPSYDQPDYGQQDSYDQQSGYDQHQGSY 126
Y + S S+ PY + + SSG + S YGQ S S GS
Sbjct: 1497 YGSGSGWSSSRGPY----ESGSSHSSGLGHRESRSGQSSGYGQHGSSSGHSSTHGQHGST 1552
Query: 127 DEQSNYDQQHDSYSQNQQSYHSQRENYSHHTQDDRRDVSRYGED----NRGYGGSQGGGR 182
QS+ QH + S Q S H Q + S + R S G+ RG G Q
Sbjct: 1553 SGQSSSCGQHGA-SSGQSSSHGQHGSGSSQSSGYGRQGSGSGQSPGHGQRGSGSRQSPSY 1611
Query: 183 GRGGYDKDGRGPMTGSSGGDRGGFKNFGGHRDYGPRTDADSESDNSDNNTIFVQGLGEGV 242
GR G GR +G G G FG H ES + +++ G G G
Sbjct: 1612 GRHG-SGSGRSSSSGQHGSGLGESSGFGHH-----------ESSSGQSSSYSQHGSGSGH 1659
Query: 243 STDQVGEFFKQIGIIKTNKKTGKPM--INLYTDKDTGKPK----GEATVSFDDPPSAKAA 296
S+ G+ + G ++ G + Y +G + G PS
Sbjct: 1660 SSGY-GQHGSRSGQSSRGERHGSSSRSSSRYGQHGSGSRQSSGHGRQGSGSGQSPSRGRH 1718
Query: 297 IDWFDGKEFHGNIIKVSFATRRPEFMRGGGSGGGRRG-RGGYRGRGGFQGRGGDPKSGDW 355
HG GSG GR RG Y R G G +SG
Sbjct: 1719 GSGLGHSSSHGQ----------------HGSGSGRSSSRGPYESRSGHSSVFGQHESGSG 1762
Query: 356 VCPNPSCGNMNFARRNSCNQCNEPRPEDSRPSGGDFRGRGYGGERGYRGRGGRGGDRGGY 415
+ + + C+Q + + S D G G + G Y
Sbjct: 1763 --HSSAYSQHGSGSGHFCSQ-GQHGSTSGQSSTFDQEGSSTGQSSSHGQHGSGSSQSSSY 1819
Query: 416 GGDRSGGGYGGDRSSGGGYSGDRSGGGYGGDRSGG-------GYGGDRGGGYGGDRGGGY 468
G SG G R G SG S G G SG G G + G+G +
Sbjct: 1820 GQQGSGSGQSPSRGRHGSGSGHSSSYGQHGSGSGWSSSSGRHGSGSGQSSGFGHHESSSW 1879
Query: 469 GGDRGGGYGGDRGGYGGDRGGGYGGDRGGYGGDRGGYGGDRGGYGGDRGGYG-GDRSRGG 527
+ GY G G G R G RG G G G +G G R G
Sbjct: 1880 ---QSSGYTQHGSGSGHSSSYEQHGSRSGQ-SSRGEQHGSSSGSSSSYGQHGSGSRQSLG 1935
Query: 528 YGGDRGGGSGYGGDRSGGYGGDRSG-----GGYGGDRGGGYGGDRGGYGGKMG 575
+ G G GSG S G G SG G YG G G+ RG Y G
Sbjct: 1936 H-GQHGSGSGQSPSPSRGRHGSGSGQSSSYGPYGS--GSGWSSSRGPYESGSG 1985
Score = 110 bits (275), Expect = 4e-24
Identities = 155/610 (25%), Positives = 210/610 (34%), Gaps = 77/610 (12%)
Query: 6 SYGQSGGEQQSYSTYGNPGSQGYGQASQSYSGYGQTTDSSYGQNYSGYSSYGQSYSQSYG 65
S GQ G ST+ GS +S G G + SSYGQ SG GQS S+
Sbjct: 2249 SQGQHGSTSGQSSTFDQEGSSTGQSSSHGQHGSGSSQSSSYGQQGSGS---GQSPSRGRH 2305
Query: 66 GYENQKQSSYSQQPYNNQGQQQNMESSGSQGGRAPSYDQPDYGQQDSYDQQSGYDQHQGS 125
G + SSY Q + G + GS G++ + + S Q SGY QH
Sbjct: 2306 GSGSGHSSSYGQHG-SGSGWSSSSGRHGSGSGQSSGFGH----HESSSWQSSGYTQHGSG 2360
Query: 126 YDEQSNYDQQHDSYSQNQQ-----SYHSQRENYSHHTQDDRRDVSRYGEDNRGYGGSQGG 180
S+Y+Q Q+ + S +Y H R+ + +G+ G G S
Sbjct: 2361 SGHSSSYEQHGSRSGQSSRGERHGSSSGSSSSYGQHGSGSRQSLG-HGQHGSGSGQSPSP 2419
Query: 181 GRGR---GGYDKDGRGPMTGSSG--GDRGGFKNFGGHRD-YGPRTDADSESDNSDNNTIF 234
RGR G P SG RG +++ GH G R +S
Sbjct: 2420 SRGRHGSGSGQSSSYSPYGSGSGWSSSRGPYESGSGHSSGLGHRESRSGQSS-------- 2471
Query: 235 VQGLGEGVSTDQVGEFFKQIGIIKTNKKTGKPMINLYTDKDTGKPKGEATVSFDDPPSAK 294
G G+ S+ Q G +G+ +G+ S+
Sbjct: 2472 --GYGQHGSSSGHSSTHGQHG-----STSGQSSSCGQHGASSGQSSSHGQHGSGSSQSSG 2524
Query: 295 AAIDWFDGKEFHGNIIKVSFATRRPEFMRGGGSGGGRRGRGGYRGRGGFQGRG-GDPKSG 353
+ G+ + S + + P + R G SG GR G G G + G G +S
Sbjct: 2525 YGRQGSGSGQSPGHGQRGSGSRQSPSYGRHG-SGSGRSSSSGQHGSGLGESSGFGHHESS 2583
Query: 354 DWVCPNPSCGNMNFARRNSCNQCNEPRPEDSRPSGGDFRGRGYGGERGYRGRGGR--GGD 411
S + ++++ S + + + SG RG +G G G+ G
Sbjct: 2584 -------SGQSSSYSQHGSGSGHSSGYGQHGSRSGQSSRGERHGSSSGSSSHYGQHGSGS 2636
Query: 412 RGGYGGDRSGGGYGGDRSSGGGYSGDRSGGGYGGDRSGGGYGGDRGG-----GYGG---- 462
R G R G G G S G SG +G SG G RG G+
Sbjct: 2637 RQSSGHGRQGSGSGQSPSRGRHGSGLGHSSSHGQHGSGSGRSSSRGPYESRLGHSSVFGQ 2696
Query: 463 -DRGGGYGG---DRGGGYG-----GDRGGYGG-----DRGGGYGGDRGGYGGDRGGYGGD 508
+ G G+ G G G G G G D+ G G YG RG
Sbjct: 2697 HESGSGHSSAYSQHGSGSGHFCSQGQHGSTSGQSSTFDQEGSSTGQSSSYG-HRGSGSSQ 2755
Query: 509 RGGYGGDRGGYGGDRSRGGYGGDRGGGSGYGGDRSGGYGGDRSGGGYGGDRGGGYGGDRG 568
GYG G G S G +G G S YG SG G SG G G G D
Sbjct: 2756 SSGYGRHGAGSGQSLSHGRHGSGSGQSSSYGQHGSGS--GQSSGYS---QHGSGSGQD-- 2808
Query: 569 GYGGKMGGRN 578
GY GG N
Sbjct: 2809 GYSYCKGGSN 2818
Score = 108 bits (270), Expect = 1e-23
Identities = 152/607 (25%), Positives = 212/607 (34%), Gaps = 92/607 (15%)
Query: 7 YGQSGGEQQSYSTYGNPGSQGYGQASQSYSGYGQTTDSSYGQNYSGYSSYGQSYSQSYGG 66
+G S G SY +G+ Q G Q SG GQ+ S G++ SG S SYG
Sbjct: 1913 HGSSSGSSSSYGQHGSGSRQSLGHG-QHGSGSGQSPSPSRGRHGSG-----SGQSSSYGP 1966
Query: 67 YENQKQSSYSQQPYNN-QGQQQNMESSGSQGGRAPSYDQPDYGQQDSYDQQSGYDQHQGS 125
Y + S S+ PY + G + S+ G++ Y Q +G + G QH GS
Sbjct: 1967 YGSGSGWSSSRGPYESGSGHSSGLGHRESRSGQSSGYGQ--HGSSSGHSSTHG--QH-GS 2021
Query: 126 YDEQSNYDQQHDSYSQNQQSYHSQRENYSHHTQDDRRDVSRYGED----NRGYGGSQGGG 181
QS+ QH + S Q S H Q + S + R S G+ RG G Q
Sbjct: 2022 ASGQSSSCGQHGA-SSGQSSSHGQHGSGSSQSSGYGRQGSGSGQSPGHGQRGSGSRQSPS 2080
Query: 182 RGRGGYDKDGRGPMTGSSGGDRGGFKNFGGHRDYGPRTDADSESDNSDNNTIFVQGLGEG 241
GR G GR +G G G FG H ES + +++ G G G
Sbjct: 2081 YGRHG-SGSGRSSSSGQHGPGLGESSGFGHH-----------ESSSGQSSSYSQHGSGSG 2128
Query: 242 VSTDQVGEFFKQIGIIKTNKKTGKPMINLYTDKDTGKPKGEATVSFDDPPSAKAAIDWFD 301
S+ G + ++G+ G+ G ++ S S++
Sbjct: 2129 HSS----------GYGQHGSRSGQ--------SSRGERHGSSSGS-----SSRYGQHGSG 2165
Query: 302 GKEFHGNIIKVSFATRRPEFMRGG------------GSGGGRRG-RGGYRGRGGFQGRGG 348
++ G+ + S + P R G GSG GR RG Y R G G
Sbjct: 2166 SRQSSGHGRQGSGSGHSPSRGRHGSGSGHSSSHGQHGSGSGRSSSRGPYESRSGHSSVFG 2225
Query: 349 DPKSGDWVCPNPSCGNMNFARRNSCNQCNEPRPEDSRPSGGDFRGRGYGGERGYRGRGGR 408
+SG + + + C+Q + + S D G G + G
Sbjct: 2226 QHESGSG--HSSAYSQHGSGSGHFCSQ-GQHGSTSGQSSTFDQEGSSTGQSSSHGQHGSG 2282
Query: 409 GGDRGGYGGDRSGGGYGGDRSSGGGYSGDRSGGGYGGDRSGG-------GYGGDRGGGYG 461
YG SG G R G SG S G G SG G G + G+G
Sbjct: 2283 SSQSSSYGQQGSGSGQSPSRGRHGSGSGHSSSYGQHGSGSGWSSSSGRHGSGSGQSSGFG 2342
Query: 462 GDRGGGYGGD------RGGGYGGDRGGYGGDRGGGYGGDR-GGYGGDRGGYG----GDRG 510
+ G G+ +G G G+R G G YG G R
Sbjct: 2343 HHESSSWQSSGYTQHGSGSGHSSSYEQHGSRSGQSSRGERHGSSSGSSSSYGQHGSGSRQ 2402
Query: 511 GYGGDRGGYGGDRSRGGYGGDRGGGSGYGGDRSGGYGGDRSGGGYGGDRGGGYGGDRGGY 570
G + G G +S G G GSG +S Y SG G+ RG G G+
Sbjct: 2403 SLGHGQHGSGSGQSPSPSRGRHGSGSG----QSSSYSPYGSGSGWSSSRGPYESG--SGH 2456
Query: 571 GGKMGGR 577
+G R
Sbjct: 2457 SSGLGHR 2463
Score = 107 bits (268), Expect = 2e-23
Identities = 155/624 (24%), Positives = 205/624 (32%), Gaps = 71/624 (11%)
Query: 2 SDSGS---YGQSGGEQQSYSTYGNPGSQGYGQASQSYSGYGQTTDSSYGQNYSGYSSYGQ 58
S SGS YGQ G + S +G GS S+ G G SS+GQ+ SG
Sbjct: 2151 SSSGSSSRYGQHGSGSRQSSGHGRQGSGSGHSPSRGRHGSGSGHSSSHGQHGSG-----S 2205
Query: 59 SYSQSYGGYENQK-QSSYSQQPYNNQGQQQNMESSGSQGGRAPSYDQ--PDYGQQDSYDQ 115
S S G YE++ SS Q + G GS G S Q GQ ++DQ
Sbjct: 2206 GRSSSRGPYESRSGHSSVFGQHESGSGHSSAYSQHGSGSGHFCSQGQHGSTSGQSSTFDQ 2265
Query: 116 QSGYDQHQGSYDEQSNYDQQHDSYSQNQQSYHSQRENYSHHTQDDRRDVSRYGEDNRGYG 175
+ S+ + + Q SY Q Q S Q + H S YG+ G G
Sbjct: 2266 EGSSTGQSSSHGQHGSGSSQSSSYGQ-QGSGSGQSPSRGRHGSGSGHS-SSYGQHGSGSG 2323
Query: 176 GSQGGGR-GRGGYDKDGRGPMTGSSGGDRGGFKNFGGHRDYGPRTDADSESDNSDNNTIF 234
S GR G G G G SS G ++ G S S S
Sbjct: 2324 WSSSSGRHGSGSGQSSGFGHHESSSWQSSGYTQHGSGSGHSSSYEQHGSRSGQSSRGERH 2383
Query: 235 VQGLGEGVSTDQVGEFFKQ-IGIIKTNKKTGKPMINLYTDKDTGKPKGEATVSFDDPPSA 293
G S Q G +Q +G + +G+ +G + + +
Sbjct: 2384 GSSSGSSSSYGQHGSGSRQSLGHGQHGSGSGQSPSPSRGRHGSGSGQSSSYSPYGSGSGW 2443
Query: 294 KAAIDWFDGKEFHGNIIKVSFATRRPEFMRGGGSGGGRRGRGGYRGRGGFQGRGGDPKSG 353
++ ++ H S E G SG G+ G G G+ G
Sbjct: 2444 SSSRGPYESGSGH------SSGLGHRESRSGQSSGYGQHGSSS--GHSSTHGQHGSTSG- 2494
Query: 354 DWVCPNPSCGNMNFARRNSCNQCNEPRPEDSRPSGGDFRGRGYG-----GERGYR----- 403
+ SCG + S + + S+ SG +G G G G+RG
Sbjct: 2495 ----QSSSCGQHGASSGQSSSH-GQHGSGSSQSSGYGRQGSGSGQSPGHGQRGSGSRQSP 2549
Query: 404 --GRGGRG--------------GDRGGYGGDRSGGGYGGDRSSGGGYSGDRSGGGYGGDR 447
GR G G G+ G+G S G S G SG SG G G R
Sbjct: 2550 SYGRHGSGSGRSSSSGQHGSGLGESSGFGHHESSSGQSSSYSQHGSGSGHSSGYGQHGSR 2609
Query: 448 SGGGYGGDRGGGYGGDRG----GGYGGDRGGGYGGDRGGYGGDRGGGYGGDRGGYGGDRG 503
SG G+R G G G G + G+G G G G G G+ G
Sbjct: 2610 SGQSSRGERHGSSSGSSSHYGQHGSGSRQSSGHGRQGSGSGQSPSRGRHGSGLGHSSSHG 2669
Query: 504 GYGGDRGGYGGDRGGYGGDRSRGGYGGDRGGGSGYG------GDRSG-----GYGGDRSG 552
+G G RG Y G GSG+ G SG G G SG
Sbjct: 2670 QHGSG-SGRSSSRGPYESRLGHSSVFGQHESGSGHSSAYSQHGSGSGHFCSQGQHGSTSG 2728
Query: 553 GGYGGDRGGGYGGDRGGYGGKMGG 576
D+ G G YG + G
Sbjct: 2729 QSSTFDQEGSSTGQSSSYGHRGSG 2752
Score = 105 bits (263), Expect = 9e-23
Identities = 143/579 (24%), Positives = 187/579 (32%), Gaps = 108/579 (18%)
Query: 6 SYGQSGGEQQSYSTYGNPGSQGYGQASQSYSGYGQTTDSSYGQNYSGYSSYGQSYSQSYG 65
S GQ G ST+ GS +S G G + SSYGQ SG GQS S+
Sbjct: 1779 SQGQHGSTSGQSSTFDQEGSSTGQSSSHGQHGSGSSQSSSYGQQGSGS---GQSPSRGRH 1835
Query: 66 GYENQKQSSYSQQPYNNQGQQQNMESSGSQGGRAPSYDQPDYGQQDSYDQQSGYDQHQGS 125
G + SSY Q + G + GS G++ + + S Q SGY QH
Sbjct: 1836 GSGSGHSSSYGQHG-SGSGWSSSSGRHGSGSGQSSGFGH----HESSSWQSSGYTQHGSG 1890
Query: 126 YDEQSNYDQQHDSYSQNQQ-----SYHSQRENYSHHTQDDRRDVSRYGEDNRGYGGSQGG 180
S+Y+Q Q+ + S +Y H R+ + +G+ G G S
Sbjct: 1891 SGHSSSYEQHGSRSGQSSRGEQHGSSSGSSSSYGQHGSGSRQSLG-HGQHGSGSGQSPSP 1949
Query: 181 GRGRGGYDKDGRGPMTGSSGGDRGGFKNFGGHRDYGPRTDADSESDNSDNNTIFVQGLGE 240
RGR G G SS G G + R GP S GLG
Sbjct: 1950 SRGR-----HGSGSGQSSSYGPYGSGSGWSSSR--GPYESGSGHSS----------GLGH 1992
Query: 241 GVSTDQVGEFFKQIGIIKTNKKTGKPMINLYTDKDTGKPKGEATVSFDDPPSAKAAIDWF 300
S + Q G + T G+
Sbjct: 1993 RESRSGQSSGYGQHGSSSGHSST----------------HGQ------------------ 2018
Query: 301 DGKEFHGNIIKVSFATRRPEFMRGGGSGGGRRGRGGYRGRG-GFQGRGGDPKSGDWVCPN 359
HG+ S + + G S G+ G G + G G QG G G +
Sbjct: 2019 -----HGSASGQSSSCGQHGASSGQSSSHGQHGSGSSQSSGYGRQGSGSGQSPGHGQRGS 2073
Query: 360 PSCGNMNFARRNSCNQCNEPRPEDSRPSGGDFRGRGYGGERGYRGRGGRGGDRGGYGGDR 419
S + ++ R S G G G G G G+ G+G
Sbjct: 2074 GSRQSPSYGRHGS--------------------GSGRSSSSGQHGPGL--GESSGFGHHE 2111
Query: 420 SGGGYGGDRSSGGGYSGDRSGGGYGGDRSGGGYGGDRGGGYGGDRGGGYGGDRGGGYGGD 479
S G S G SG SG G G RSG G+R G G YG
Sbjct: 2112 SSSGQSSSYSQHGSGSGHSSGYGQHGSRSGQSSRGERHGSSSGS---------SSRYGQH 2162
Query: 480 RGGYGGDRGGGYGGDRGGYGGDRGGYG---GDRGGYGGDRGGYGGDRSRGGYGGDRGGGS 536
G G G G G+ RG +G G +G G G SRG Y R G S
Sbjct: 2163 GSGSRQSSGHGRQGSGSGHSPSRGRHGSGSGHSSSHGQHGSGSGRSSSRGPY-ESRSGHS 2221
Query: 537 GYGGDRSGGYGGDRSGGGYGGDRGGGYGGDRGGYGGKMG 575
G G G + +G G G+ +G +G G
Sbjct: 2222 SVFGQHESGSGHSSAYSQHGS--GSGHFCSQGQHGSTSG 2258
Score = 103 bits (257), Expect = 4e-22
Identities = 154/634 (24%), Positives = 228/634 (35%), Gaps = 81/634 (12%)
Query: 4 SGSYGQSG-GEQQSYST----YGNPGSQGYGQ------ASQSYSGYGQTTDSSYGQNYSG 52
S S+GQ G G SYS G+ + G+GQ S YS +G + S Q G
Sbjct: 319 SSSHGQHGSGSSYSYSRGHYESGSGQTSGFGQHESGSGQSSGYSKHGSGSGHSSSQGQHG 378
Query: 53 YSSYGQSYSQSYGGYENQKQSSYSQ-QPYNNQGQQQNMESSGSQGGRAPSYDQ--PDYGQ 109
S+ GQ+ S G +++ SSY Q + + + SSGS G++P + Q GQ
Sbjct: 379 -STSGQASSSGQHGSSSRQSSSYGQHESASRHSSGRGQHSSGS--GQSPGHGQRGSGSGQ 435
Query: 110 QDSYDQQS---GYDQHQGSYDEQSNYDQ---QHDSYSQNQQSYHSQRENYSHHTQDDRRD 163
S Q G G Y S Y H+S S++ Y +Q + S H+ +
Sbjct: 436 SPSSGQHGTGFGRSSSSGPYVSGSGYSSGFGHHESSSEHSSGY-TQHGSGSGHSSGHGQH 494
Query: 164 VSRYGEDNRG------------YGGSQGGGRGRGGYDKDGRG---PMTGSSGGDRGGFKN 208
SR G+ +RG YG G R G+ + G G + S G G +
Sbjct: 495 GSRSGQSSRGERQGSSAGSSSSYGQHGSGSRQSLGHSRHGSGSGQSPSPSRGRHESGSRQ 554
Query: 209 FGGHRDYGPRTDADSESDNSDNNTIFVQGLGEGVS----TDQVGEFFKQIGIIKTNKKTG 264
+ +G + S ++ + GLG S + G+ G T+ + G
Sbjct: 555 SSSYGPHGYGSGRSSSRGPYESGSGHSSGLGHQESRSGQSSGYGQHGSSSGHSSTHGQHG 614
Query: 265 KPMINLYTDKDTGKPKGEATVSFDDPPSAKAAIDWFDGKEFHGNIIKVSFATRRPEFMRG 324
+ G G+++ + + + G++ G+ S +F
Sbjct: 615 STSGQSSSCGQHGATSGQSSSHGQHGSGSSQSSRY--GQQGSGSGQSPSRGRHGSDFGHS 672
Query: 325 G-----GSGGGRRGRGGYRGRGGFQGRGGDPKSGDWVCPNPSCGNMNFARRNSCNQCNEP 379
GSG G G G Q G KSG S + +++ S + +
Sbjct: 673 SSYGQHGSGSGWSSSNGPHGSVSGQSSGFGHKSG-------SGQSSGYSQHGSGSSHSSG 725
Query: 380 RPEDSRPSGGDFRGRGYGGERG----YRGRGGRGGDRGGYGGDRSGGGYGGDR-----SS 430
+ SG R +G G Y G G+G SG G+ R SS
Sbjct: 726 YRKHGSRSGQSSRSEQHGSSSGLSSSYGQHGSGSHQSSGHGRQGSGSGHSPSRVRHGSSS 785
Query: 431 GGGYSGDRSGGGYGGDRSGGGY--GGDRGGGYG-GDRGGGYGGDRGG---GYGGDRGGYG 484
G S + G G S G Y G + G+G + G G G + G G+ +G +G
Sbjct: 786 GHSSSHGQHGSGTSCSSSCGHYESGSGQASGFGQHESGSGQGYSQHGSASGHFSSQGRHG 845
Query: 485 GDRG-GGYGGDRGGYGGDRGGYGGDRGG--YGGDRGGYGGDRSRGGYGGDRGGGSGYGGD 541
G G G YG + RG +G + G RG GSG
Sbjct: 846 STSGQSSSSGQHDSSSGQSSSYGQHESASHHASGRGRHGSGSGQSPGHGQRGSGSG---- 901
Query: 542 RSGGYGGDRSGGGYGGDRG--GGYGGDRGGYGGK 573
+S YG SG G G G G G+G K
Sbjct: 902 QSPSYGRHGSGSGRSSSSGRHGSGSGQSSGFGHK 935
Score = 99.8 bits (247), Expect = 6e-21
Identities = 147/614 (23%), Positives = 202/614 (32%), Gaps = 73/614 (11%)
Query: 5 GSYGQSGGEQQSYSTYGNPGSQGYGQASQSYSGYGQTTDSSYGQNYSGYSSYGQSYSQSY 64
G + G +YS +G+ GS + Q S GQ+ S++ Q SS GQS S +
Sbjct: 1285 GQHESGSGHSSAYSQHGS-GSGHFCSQGQHGSTSGQS--STFDQE---GSSTGQSSSYGH 1338
Query: 65 GGYENQKQSSYSQQPYNNQGQQQNMESSGSQGGRAPSYDQPDYGQQDSYD---------Q 115
G + + S Y + + GQ + GS G + SY Q G S Q
Sbjct: 1339 RGSGSSQSSGYGRHGAGS-GQSPSRGRHGSGSGHSSSYGQHGSGSGWSSSSGRHGSGSGQ 1397
Query: 116 QSGYDQHQGSYDEQSNYDQQHDSYSQNQQSYHSQRENYSHHTQDDRR-----DVSRYGED 170
SG+ H+ S QS+ QH S S + SY ++ +R S YG+
Sbjct: 1398 SSGFGHHESS-SWQSSGCTQHGSGSGHSSSYEQHGSRSGQSSRGERHGSSSGSSSSYGQ- 1455
Query: 171 NRGYGGSQGGGRGRGGYDKDGRGPMTGSSGGDRG-GFKNFGGHRDYGPRTDADSESDNSD 229
G G Q G G+ G G G S G G G + YG + S +
Sbjct: 1456 -HGSGSRQSLGHGQHG---SGSGQSPSPSRGRHGSGSGQSSSYSPYGSGSGWSSSRGPYE 1511
Query: 230 NNTIFVQGLGEGVSTDQVGEFFKQIGIIKTNKKTGKPMINLYTDKDTGKPKGEATVSFDD 289
+ + GLG S + Q G + T G G+++
Sbjct: 1512 SGSSHSSGLGHRESRSGQSSGYGQHGSSSGHSS---------THGQHGSTSGQSSSCGQH 1562
Query: 290 PPSAKAAIDWFDGKEFHGNIIKVSFATRRPEFMRGGGSGGGRRGRGGYRGRG-GFQGRGG 348
S+ + HG+ S R G G G+RG G + G G G
Sbjct: 1563 GASSGQS----SSHGQHGSGSSQSSGYGRQGSGSGQSPGHGQRGSGSRQSPSYGRHGSGS 1618
Query: 349 DPKSGDWVCPNPSCGNMNFARRNSCNQCNEPRPEDSRPSGGDFRGRGYGGERGYRGRGGR 408
S + + F S + + + SG +G G RG R
Sbjct: 1619 GRSSSSGQHGSGLGESSGFGHHESSSGQSSSYSQHGSGSGHSSGYGQHGSRSGQSSRGER 1678
Query: 409 GGDRGGYGGDRSGGGYGGDRSSGGGYSGDRSGGGYGGDRSGGGYG-----GDRGGGYGGD 463
G G G +SSG G G SG R G G G G G G G
Sbjct: 1679 HGSSSRSSSRYGQHGSGSRQSSGHGRQGSGSGQSPSRGRHGSGLGHSSSHGQHGSGSGRS 1738
Query: 464 RGGGYGGDRGGG---YGGDRGGYGGDRGGGYGGDRGGYGGDRGGYGGDRG---------- 510
G R G +G G G G G+ +G +G G
Sbjct: 1739 SSRGPYESRSGHSSVFGQHESGSGHSSAYSQHGSGSGHFCSQGQHGSTSGQSSTFDQEGS 1798
Query: 511 --GYGGDRGGYGGDRSRGGYGGDRGGGSGY---------GGDRSGGYGGDRSGGGYGGDR 559
G G +G S+ G +G GSG G S YG SG G+
Sbjct: 1799 STGQSSSHGQHGSGSSQSSSYGQQGSGSGQSPSRGRHGSGSGHSSSYGQHGSGSGWSSSS 1858
Query: 560 G--GGYGGDRGGYG 571
G G G G+G
Sbjct: 1859 GRHGSGSGQSSGFG 1872
Score = 84.3 bits (207), Expect = 3e-16
Identities = 131/544 (24%), Positives = 185/544 (34%), Gaps = 64/544 (11%)
Query: 57 GQSYSQSYGG------YENQKQSSYSQQPYNNQGQQQNMESSGSQGGRAPSYDQPDYGQQ 110
G+ Y Q G +++Q++ +++ N + + SS S G + Y +
Sbjct: 90 GKDYCQVSGSKLRDDTHQHQEEQEETEKEENKRQESSFSHSSWSAG------ENDSYSRN 143
Query: 111 DSYDQQSGYDQHQGSYDEQSNYDQQHDSYSQNQQSYHSQRENYSHHTQDDRRDVSRYGED 170
+ G + Q ++ QH+SYS SY Q + SH + + S G+
Sbjct: 144 VRGSLKPGTESISRRLSFQRDFSGQHNSYSGQSSSYGEQNSD-SHQSSGRGQCGSGSGQS 202
Query: 171 -NRGYGGSQGGGRGRGGYDKDGRGPMTG-----SSGGDRGGFKNFG---GHRD-YGPRTD 220
N G GS G G G +G SS G G+ G GH YG
Sbjct: 203 PNYGQHGSGSGQSSSNDTHGSGSGQSSGFSQHKSSSGQSSGYSQHGSGSGHSSGYGQHGS 262
Query: 221 ADSESDNSDNNTIFVQGLGEGVSTDQVGEFFKQIGIIKTNKKTGKPMINLYTDKDTGKPK 280
+S + + G S Q G +Q + + +G + +
Sbjct: 263 RSGQSSRGERHR---SSSGSSSSYGQHGSGSRQ-SLGHGRQGSG----SRQSPSHVRHGS 314
Query: 281 GEATVSFDDPPSAKAAIDWFDGKEFHGNIIKVSFATRRPEFMRGGGSGGGRRGRGGYRGR 340
G S + ++ + G G+ F + G G G G G
Sbjct: 315 GSGHSSSHGQHGSGSSYSYSRGHYESGSGQTSGFG----QHESGSGQSSGYSKHGSGSGH 370
Query: 341 GGFQGRGGDPKSGDWVCPNPSCGNMNFARRNSCNQCNEPRPEDSRPSGGDFRGRGYGGER 400
QG+ G SG + S + + +R++S +E S G G G
Sbjct: 371 SSSQGQHGS-TSGQ---ASSSGQHGSSSRQSSSYGQHESASRHSSGRGQHSSGSGQSPGH 426
Query: 401 GYRGRGGRGGDRGGYGGDRSGGGYGGDRSSGGGYSGDRSGGGYGGDRSGGGYGGDRGGGY 460
G RG G G + G G+G SSG SG G+G S + GY
Sbjct: 427 GQRGSGSGQSPSSG----QHGTGFGRSSSSGPYVSGSGYSSGFGHHES----SSEHSSGY 478
Query: 461 GGDRGGGYGGDRGGGYGGDRGGYG--GDRGGGYGGDRGGYG----GDRGGYGGDRGGYGG 514
G G G G G G R G G+R G G YG G R G R G G
Sbjct: 479 -TQHGSGSGHSSGHGQHGSRSGQSSRGERQGSSAGSSSSYGQHGSGSRQSLGHSRHGSG- 536
Query: 515 DRGGYGGDRSRGGY-GGDRGGGS----GYGGDRSGGYGGDRSGGGYGGDRG--GGYGGDR 567
G SRG + G R S GYG RS G SG G+ G G
Sbjct: 537 --SGQSPSPSRGRHESGSRQSSSYGPHGYGSGRSSSRGPYESGSGHSSGLGHQESRSGQS 594
Query: 568 GGYG 571
GYG
Sbjct: 595 SGYG 598
Score = 67.4 bits (163), Expect = 4e-11
Identities = 118/507 (23%), Positives = 154/507 (30%), Gaps = 66/507 (13%)
Query: 119 YDQHQGSYDEQSNYDQQHDSYSQNQQSYHSQRENYSHHTQDDRRDVSRYGEDNRGY--GG 176
Y Q GS + Q + ++ Q ++SH + + S Y + RG G
Sbjct: 93 YCQVSGSKLRDDTHQHQEEQEETEKEENKRQESSFSHSSWSAGENDS-YSRNVRGSLKPG 151
Query: 177 SQGGGRGRGGYDKDGRGPMTGSSGGDRG-GFKNFGGHRDYGPRTDADSESDNSDNNTIFV 235
++ R R + +D G SG G +N H+ G R S S S N
Sbjct: 152 TESISR-RLSFQRDFSGQHNSYSGQSSSYGEQNSDSHQSSG-RGQCGSGSGQSPNYGQHG 209
Query: 236 QGLGEGVSTDQVGEFFKQIGIIKTNKKTGKPMINLYTDKDTGKPKGEATVSFDDPPSAKA 295
G G+ S D G Q +K + +G+ G + S+
Sbjct: 210 SGSGQSSSNDTHGSGSGQSSGFSQHKSS------------SGQSSGYSQHGSGSGHSS-- 255
Query: 296 AIDWFDGKEFHGNIIKVSFATRRPEFMRGGGSGGGRRGRGGYRGRG-GFQGRGGDPKSGD 354
G HG+ S R G S G+ G G + G G QG G
Sbjct: 256 ------GYGQHGSRSGQSSRGERHRSSSGSSSSYGQHGSGSRQSLGHGRQGSGSRQSPSH 309
Query: 355 WVCPNPSCGNMNFARRNSCNQCNEPRPEDSRPSG----------GDFRGRGYGGERGYRG 404
+ S + + + S + + R SG G + GY G
Sbjct: 310 VRHGSGSGHSSSHGQHGSGSSYSYSRGHYESGSGQTSGFGQHESGSGQSSGYSKHGSGSG 369
Query: 405 RGGRGGDRGGYGGDRSGGGYGGDRSS-----GGGYSGDRSGGGYGGDRSGGGYG---GDR 456
G G G S G G S G S R G G SG G G R
Sbjct: 370 HSSSQGQHGSTSGQASSSGQHGSSSRQSSSYGQHESASRHSSGRGQHSSGSGQSPGHGQR 429
Query: 457 GGGYG-----GDRGGGYGGDRGGGYGGDRGGYGGDRGGGYGGDRGGYGGDRGGYGGDRGG 511
G G G G G G+G G GY G G + G G
Sbjct: 430 GSGSGQSPSSGQHGTGFGRSSSSGPYVSGSGYSSGFGHHESSSEHSSGYTQHGSGSGHSS 489
Query: 512 YGGDRGGYGGDRSRG-GYGGDRGGGSGYGGDRSG---GYGGDRSGGGYG----------- 556
G G G SRG G G S YG SG G R G G G
Sbjct: 490 GHGQHGSRSGQSSRGERQGSSAGSSSSYGQHGSGSRQSLGHSRHGSGSGQSPSPSRGRHE 549
Query: 557 -GDRGGGYGGDRGGYGGKMGGRNDYRN 582
G R G G G+ R Y +
Sbjct: 550 SGSRQSSSYGPHGYGSGRSSSRGPYES 576
Score = 61.6 bits (148), Expect = 2e-09
Identities = 73/269 (27%), Positives = 97/269 (36%), Gaps = 37/269 (13%)
Query: 4 SGSYGQSGGEQQSYSTYGNPG-----SQGYGQ---ASQSYSGYGQTTDSSYGQNYSGYSS 55
S S+GQ G S YG G S G+GQ S+ YG+ S + SG
Sbjct: 2509 SSSHGQHGSGSSQSSGYGRQGSGSGQSPGHGQRGSGSRQSPSYGRHGSGSGRSSSSGQHG 2568
Query: 56 YGQSYSQSYGGYENQ--KQSSYSQ--------QPYNNQGQQQNMESSGSQGGRAPSYDQP 105
G S +G +E+ + SSYSQ Y G + S G + G + S
Sbjct: 2569 SGLGESSGFGHHESSSGQSSSYSQHGSGSGHSSGYGQHGSRSGQSSRGERHG-SSSGSSS 2627
Query: 106 DYGQQDSYDQQSGYDQHQGSYDEQSNYDQQHDSYSQNQQSYHSQRENYSHHTQDDRRDVS 165
YGQ S +QS QGS QS +H S S H Q + S + S
Sbjct: 2628 HYGQHGSGSRQSSGHGRQGSGSGQSPSRGRHGS-GLGHSSSHGQHGSGSGRSSSRGPYES 2686
Query: 166 RYGEDNRGYGGSQGGGRGRGGYDKDGRGP-------MTGSSGGDRGGF----KNFGGHRD 214
R G + +G + G Y + G G GS+ G F + G
Sbjct: 2687 RLGHSS-VFGQHESGSGHSSAYSQHGSGSGHFCSQGQHGSTSGQSSTFDQEGSSTGQSSS 2745
Query: 215 YGPRTDADSESDNSDNNTIFVQGLGEGVS 243
YG R S+S + G G G S
Sbjct: 2746 YGHRGSGSSQSSGYGRH-----GAGSGQS 2769
Score = 61.6 bits (148), Expect = 2e-09
Identities = 59/209 (28%), Positives = 80/209 (38%), Gaps = 13/209 (6%)
Query: 2 SDSGS---YGQSGGEQQSYSTYGNPGSQGYGQASQSYSGYGQTTDSSYGQNYSGYSSYGQ 58
S SGS YGQ G + S +G GS S+ G G SS+GQ+ SG
Sbjct: 2621 SSSGSSSHYGQHGSGSRQSSGHGRQGSGSGQSPSRGRHGSGLGHSSSHGQHGSG-----S 2675
Query: 59 SYSQSYGGYENQK-QSSYSQQPYNNQGQQQNMESSGSQGGRAPSYDQ--PDYGQQDSYDQ 115
S S G YE++ SS Q + G GS G S Q GQ ++DQ
Sbjct: 2676 GRSSSRGPYESRLGHSSVFGQHESGSGHSSAYSQHGSGSGHFCSQGQHGSTSGQSSTFDQ 2735
Query: 116 QSGYDQHQGSYDEQSNYDQQHDSYSQNQQSYHSQRENYSHHTQDDRRDVSRYGEDNRGYG 175
+ SY + + Q Y ++ Q ++ H + S YG+ G G
Sbjct: 2736 EGSSTGQSSSYGHRGSGSSQSSGYGRHGAG-SGQSLSHGRHGSGSGQS-SSYGQHGSGSG 2793
Query: 176 GSQGGGRGRGGYDKDGRGPMTGSSGGDRG 204
S G + G +DG G S D G
Sbjct: 2794 QSSGYSQHGSGSGQDGYSYCKGGSNHDGG 2822
Score = 46.6 bits (109), Expect = 6e-05
Identities = 43/149 (28%), Positives = 55/149 (36%), Gaps = 22/149 (14%)
Query: 6 SYGQSGGEQQSYSTYGNPGSQGYGQASQSYSGYGQTTDSSYGQNYSGYSSYGQSYSQSYG 65
S GQ G ST+ GS +S + G G + S YG++ +G GQS S
Sbjct: 2719 SQGQHGSTSGQSSTFDQEGSSTGQSSSYGHRGSGSSQSSGYGRHGAG---SGQSLSHGRH 2775
Query: 66 GYENQKQSSYSQQPYNNQGQQQNMESSGSQGGRAPSYDQPDYGQ-QDSYDQQSGYDQH-- 122
G + + SSY Q GS G++ Y Q G QD Y G H
Sbjct: 2776 GSGSGQSSSYGQH--------------GSGSGQSSGYSQHGSGSGQDGYSYCKGGSNHDG 2821
Query: 123 --QGSYDEQSNYDQQHDSYSQNQQSYHSQ 149
GSY Y Q Q+ Y Q
Sbjct: 2822 GSSGSYFLSFPSSTSPYEYVQEQRCYFYQ 2850
Score = 42.7 bits (99), Expect = 0.001
Identities = 38/108 (35%), Positives = 45/108 (41%), Gaps = 8/108 (7%)
Query: 4 SGSYGQSGGEQQSYSTYGNPGSQGYGQASQSYSGYGQTTDSSYGQNYSGYSSYGQSYSQS 63
S SYG G S YG G+ S G G SSYGQ+ SG S YSQ
Sbjct: 2743 SSSYGHRGSGSSQSSGYGRHGAGSGQSLSHGRHGSGSGQSSSYGQHGSG-SGQSSGYSQ- 2800
Query: 64 YGGYENQKQSSYSQQPYNNQGQQQNMESSGSQGGRAPSYDQP-DYGQQ 110
+G Q SY + N+ G SSGS PS P +Y Q+
Sbjct: 2801 HGSGSGQDGYSYCKGGSNHDG-----GSSGSYFLSFPSSTSPYEYVQE 2843
Score = 37.4 bits (85), Expect = 0.039
Identities = 25/92 (27%), Positives = 35/92 (38%), Gaps = 6/92 (6%)
Query: 2 SDSGSYGQSGGEQQSYSTYGNPGSQGYGQASQSYSGYGQTTDSSYGQNYSGYSSYGQSYS 61
S S YG+ G ++G GS +S G G S Y Q+ SG G SY
Sbjct: 2754 SQSSGYGRHGAGSGQSLSHGRHGSGSGQSSSYGQHGSGSGQSSGYSQHGSGSGQDGYSYC 2813
Query: 62 QSYGGYENQKQSSY------SQQPYNNQGQQQ 87
+ ++ SY S PY +Q+
Sbjct: 2814 KGGSNHDGGSSGSYFLSFPSSTSPYEYVQEQR 2845
>gi|195972866 keratin 10 [Homo sapiens]
Length = 584
Score = 122 bits (307), Expect = 7e-28
Identities = 73/144 (50%), Positives = 77/144 (53%), Gaps = 15/144 (10%)
Query: 404 GRGGRGGDRGGYGGDRSGGGYGGDRSSGGGYSGDRSGGGYGGDRSGGGYGGDRGGGYGGD 463
G G GG GG GG GGGYGG SSGGG SG GGG+GG SGGGYGG G GG
Sbjct: 455 GEGSSGG--GGRGGGSFGGGYGGG-SSGGGSSGGGHGGGHGGS-SGGGYGGGSSG--GGS 508
Query: 464 RGGGYGGDRGGGYGGDRGGYGGDRGGGYGGDRGGYGGDRGGY-GGDRGGYGGDRGGYGGD 522
GGGYGG G GG+GG GGYGG G GG GGY GG GG GGYGG
Sbjct: 509 SGGGYGG------GSSSGGHGGSSSGGYGG--GSSGGGGGGYGGGSSGGGSSSGGGYGGG 560
Query: 523 RSRGGYGGDRGGGSGYGGDRSGGY 546
S GG+ G G + Y
Sbjct: 561 SSSGGHKSSSSGSVGESSSKGPRY 584
Score = 120 bits (301), Expect = 3e-27
Identities = 68/132 (51%), Positives = 71/132 (53%), Gaps = 16/132 (12%)
Query: 436 GDRSGGGYGGDRSGGGYGGDRGGG--YGGDRGGGYGGDRGGGYGGDRGGYGGDRGGGYGG 493
G GGG GG GGGYGG GG GG GGG+GG GGGYGG G GG GGGYGG
Sbjct: 457 GSSGGGGRGGGSFGGGYGGGSSGGGSSGGGHGGGHGGSSGGGYGGGSSG-GGSSGGGYGG 515
Query: 494 DRGGYGGDRGGYGGDR-GGYGGDRGGYGGDRSRGGYGGDRGGGSGYGGDRSGGYGGDRSG 552
G GG+GG GGYGG G GG GGYG GG SG G GGYGG S
Sbjct: 516 -----GSSSGGHGGSSSGGYGGGSSGGGG----GGYG---GGSSGGGSSSGGGYGGGSSS 563
Query: 553 GGYGGDRGGGYG 564
GG+ G G
Sbjct: 564 GGHKSSSSGSVG 575
Score = 120 bits (300), Expect = 5e-27
Identities = 70/136 (51%), Positives = 75/136 (55%), Gaps = 17/136 (12%)
Query: 442 GYGGDRSGGGYGGDRGGGYGGDRGGGYGGDRGGGYGGDRGGYGGDRGGGYGGDRGGYGGD 501
G G GG GG GGGYGG GG G GGG+GG G+GG GGGYGG G G
Sbjct: 455 GEGSSGGGGRGGGSFGGGYGGGSSGG--GSSGGGHGG---GHGGSSGGGYGGGSSGGGSS 509
Query: 502 RGGYGGDRGGYGGDRGGYGGDRSRGGYGG--DRGGGSGYGGDRSGGYGGDRSGGGYGGDR 559
GGYGG G GG+GG S GGYGG GGG GYGG SG GG SGGGYGG
Sbjct: 510 GGGYGG-----GSSSGGHGGS-SSGGYGGGSSGGGGGGYGGGSSG--GGSSSGGGYGG-- 559
Query: 560 GGGYGGDRGGYGGKMG 575
G GG + G +G
Sbjct: 560 GSSSGGHKSSSSGSVG 575
Score = 112 bits (279), Expect = 1e-24
Identities = 68/146 (46%), Positives = 74/146 (50%), Gaps = 9/146 (6%)
Query: 429 SSGGGYSGDRSGGGYGGDRSGGGYGGDRGGGYGGDRGGGYGGDRGGGYGGDRGGYGGDRG 488
SS YS RSGGG GG GGG GG +G GG GG+ G G G
Sbjct: 6 SSSKHYSSSRSGGGGGGGGCGGG-GGVSSLRISSSKGSLGGGFSSGGFSGGSFSRGSSGG 64
Query: 489 GGYGGDRGGYGGDRGGYGGDRGGYGGDRGGYGGDRSRGGYGGDRGGGSGYGGDRSGGY-- 546
G +GG GGYGG GG+GG G RG YG G YGG GGGS GG GG
Sbjct: 65 GCFGGSSGGYGG-LGGFGG-----GSFRGSYGSSSFGGSYGGSFGGGSFGGGSFGGGSFG 118
Query: 547 GGDRSGGGYGGDRGGGYGGDRGGYGG 572
GG GGG+GG GGG+GGD G G
Sbjct: 119 GGGFGGGGFGGGFGGGFGGDGGLLSG 144
Score = 112 bits (279), Expect = 1e-24
Identities = 65/133 (48%), Positives = 68/133 (51%), Gaps = 17/133 (12%)
Query: 388 GGDFRGRGYGGERGYRGRGGRGGDRGGYGGDRSGGGYGGDRSSGGGYSGDRSGGGYGGDR 447
GG F G GYGG G G G GG GG G SGGGYGG S GG SGGGYGG
Sbjct: 466 GGSFGG-GYGG--GSSGGGSSGGGHGGGHGGSSGGGYGGGSSGGGS-----SGGGYGGGS 517
Query: 448 SGGGYGGDRGGGYGGDRGGGYGGDRGGGYGGDRGGYGGDRGGGYGGDRGGYGGDRGGYGG 507
S GG+GG GGYGG GG GGGYGG G G GGGYGG G GG+
Sbjct: 518 SSGGHGGSSSGGYGGGSSGG----GGGGYGGGSSGGGSSSGGGYGG-----GSSSGGHKS 568
Query: 508 DRGGYGGDRGGYG 520
G G+ G
Sbjct: 569 SSSGSVGESSSKG 581
Score = 107 bits (266), Expect = 4e-23
Identities = 65/135 (48%), Positives = 69/135 (51%), Gaps = 18/135 (13%)
Query: 401 GYRGRGGRGGDR--GGYGGDRSGGGYGGDRSSGGGYSGDRSGGGYGGDRSGGGY------ 452
G G GGRGG GGYGG SGGG G GGG+ G SGGGYGG SGGG
Sbjct: 457 GSSGGGGRGGGSFGGGYGGGSSGGGSSGG-GHGGGHGGS-SGGGYGGGSSGGGSSGGGYG 514
Query: 453 GGDRGGGYGGDRGGGYGGDRGGGYGGDRGGYGGDRGGGYGGDRGGYGGDRGGYGGDRGGY 512
GG GG+GG GGYG GG GG GGYGG GG GGYGG G GG+
Sbjct: 515 GGSSSGGHGGSSSGGYG---GGSSGGGGGGYGGGSSGGGSSSGGGYGG-----GSSSGGH 566
Query: 513 GGDRGGYGGDRSRGG 527
G G+ S G
Sbjct: 567 KSSSSGSVGESSSKG 581
Score = 94.0 bits (232), Expect = 3e-19
Identities = 68/151 (45%), Positives = 76/151 (50%), Gaps = 22/151 (14%)
Query: 396 YGGERGYRG-RGGRGGDRGGYGGDRSGGGYGGDR--SSGGGYSGDRSGGGYGGDRSGGGY 452
Y + Y R G GG GG GG GGG R SS G G S GG+ SGG +
Sbjct: 5 YSSSKHYSSSRSGGGGGGGGCGG---GGGVSSLRISSSKGSLGGGFSSGGF----SGGSF 57
Query: 453 G-GDRGGGYGGDRGGGYGGDRGGGYGGDRGGYGGDR-GGGYGGDRGGYGGDRGGYGGDRG 510
G GGG G GGYGG G G G RG YG GG YGG GG G +GG G
Sbjct: 58 SRGSSGGGCFGGSSGGYGGLGGFGGGSFRGSYGSSSFGGSYGGSFGGGSFGGGSFGG--G 115
Query: 511 GYGGDRGGYGGDRSRGGYGGDRGGGSGYGGD 541
+GG GG+GG GG+GG G G G+GGD
Sbjct: 116 SFGG--GGFGG----GGFGG--GFGGGFGGD 138
Score = 92.0 bits (227), Expect = 1e-18
Identities = 57/110 (51%), Positives = 59/110 (53%), Gaps = 16/110 (14%)
Query: 467 GYGGDRGGGYGGDRGGYGGDRGGGYGGDRGGYGGDRGGYGGDRGGYGGDRGGYGGDRSRG 526
G G GGG GG G GGGYGG G G GG+GG GG G GGYGG S G
Sbjct: 455 GEGSSGGGGRGG------GSFGGGYGGGSSGGGSSGGGHGGGHGGSSG--GGYGGGSSGG 506
Query: 527 GYGGDRGGGSGYGGDRSGGYGGDRSGGGYGGDRGGGYGGDRGGYGGKMGG 576
G GGG G GG SGG+GG S GGYGG G GG GGYGG G
Sbjct: 507 G---SSGGGYG-GGSSSGGHGGS-SSGGYGG---GSSGGGGGGYGGGSSG 548
Score = 91.3 bits (225), Expect = 2e-18
Identities = 67/145 (46%), Positives = 76/145 (52%), Gaps = 28/145 (19%)
Query: 404 GRGGRGGDRGGYGGDRS----------GGGYGGDRSSGGGYSGDRSGGG-YGGDRSGGGY 452
G GG GG GG GG S GGG+ SGG +S SGGG +GG S GGY
Sbjct: 17 GGGGGGGGCGGGGGVSSLRISSSKGSLGGGFSSGGFSGGSFSRGSSGGGCFGG--SSGGY 74
Query: 453 GGDRGGGYGGDRGGGYGGDRGGGYGGDRGGYGGDRGGGYGGDRGGYGGDRGGYGGDRGGY 512
GG G G G RG GG YGG GG G GG +GG G +GG GG+GG GG+
Sbjct: 75 GGLGGFGGGSFRGSYGSSSFGGSYGGSFGG-GSFGGGSFGG--GSFGG--GGFGG--GGF 127
Query: 513 GGDRGGYGGDRSRGGYGGDRGGGSG 537
G GG+G GG+GGD G SG
Sbjct: 128 G---GGFG-----GGFGGDGGLLSG 144
Score = 84.7 bits (208), Expect = 2e-16
Identities = 58/131 (44%), Positives = 65/131 (49%), Gaps = 21/131 (16%)
Query: 397 GGERGYRGRGGRGG--------DRGGYGGDRSGGGYGGDR----SSGGGYSGDRSGG--- 441
GG G G GG GG +G GG S GG+ G SSGGG G SGG
Sbjct: 17 GGGGGGGGCGGGGGVSSLRISSSKGSLGGGFSSGGFSGGSFSRGSSGGGCFGGSSGGYGG 76
Query: 442 --GYGGDRSGGGYGGDR-GGGYGGDRGGGYGGDRGGGYGGDRGGYGGDRGGGYGGD-RGG 497
G+GG G YG GG YGG GGG G GG +GG G GG GGG+GG GG
Sbjct: 77 LGGFGGGSFRGSYGSSSFGGSYGGSFGGGSFG--GGSFGGGSFGGGGFGGGGFGGGFGGG 134
Query: 498 YGGDRGGYGGD 508
+GGD G G+
Sbjct: 135 FGGDGGLLSGN 145
Score = 82.8 bits (203), Expect = 8e-16
Identities = 66/182 (36%), Positives = 77/182 (42%), Gaps = 57/182 (31%)
Query: 324 GGGSGGGRRGRGGYRGRGGFQGRGGDPKSGDWVCPNPSCGNMNFARRNSCNQCNEPRPED 383
GGG GGG G GG + R
Sbjct: 17 GGGGGGGGCGGGG--------------------------------------GVSSLRISS 38
Query: 384 SRPS-GGDFRGRGYGG---ERGYRGRGGRGGDRGGYGGDRSGGGYGGDRSSGGGYSGDRS 439
S+ S GG F G+ G RG G G GG GGYGG GG+GG S G Y
Sbjct: 39 SKGSLGGGFSSGGFSGGSFSRGSSGGGCFGGSSGGYGG---LGGFGGG-SFRGSYGSSSF 94
Query: 440 GGGYGGDRSGGGYGGDRGGGYGGDRGGGYGGDRGGGYGGDRGGYGGDRGGGYGGDRGGYG 499
GG YGG GG +G GG +G GG +GG GG+GG GG+GG GGG+GGD G
Sbjct: 95 GGSYGGSFGGGSFG---GGSFG---GGSFGG---GGFGG--GGFGGGFGGGFGGDGGLLS 143
Query: 500 GD 501
G+
Sbjct: 144 GN 145
Score = 72.0 bits (175), Expect = 1e-12
Identities = 54/152 (35%), Positives = 59/152 (38%), Gaps = 28/152 (18%)
Query: 325 GGSGGGRRGRGGYRGRGGFQGRGGDPKSGDWVCPNPSCGNMNFARRNSCNQCNEPRPEDS 384
G SGGG RG G + G G GG G + + +S
Sbjct: 457 GSSGGGGRGGGSFGGGYGGGSSGGGSSGGGHGGGHGGSSGGGYGGGSS------------ 504
Query: 385 RPSGGDFRGRGYGGERGYRGRGGRGGDRGGYGGDRSGGGYGGDRSSGGGYSGDRSGGGYG 444
GG G GYGG G GG GGYGG SGGG GGGY G SG G
Sbjct: 505 ---GGGSSGGGYGGGSSSGGHGGSSS--GGYGGGSSGGG-------GGGYGGGSSG---G 549
Query: 445 GDRSGGGY-GGDRGGGYGGDRGGGYGGDRGGG 475
G SGGGY GG GG+ G G G
Sbjct: 550 GSSSGGGYGGGSSSGGHKSSSSGSVGESSSKG 581
Score = 56.2 bits (134), Expect = 8e-08
Identities = 46/111 (41%), Positives = 48/111 (43%), Gaps = 19/111 (17%)
Query: 468 YGGDRGGGYGGDRGGYGGDRGGGYGGDRGGYGGDRGGYGGDRGGYGGDRGGY-GGDRSRG 526
Y R GG GG GG GGG G +G GG G GG+ GG SRG
Sbjct: 11 YSSSRSGGGGG-----GGGCGGGGGVSSLRISSSKGSLGG-----GFSSGGFSGGSFSRG 60
Query: 527 GYGGDRGGGSGYGGDRSGGYGGDRSGGGYGGDRGG-GYGGDRGGYGGKMGG 576
GG GGS SGGYGG G G G RG G G YGG GG
Sbjct: 61 SSGGGCFGGS------SGGYGG-LGGFGGGSFRGSYGSSSFGGSYGGSFGG 104
Score = 46.6 bits (109), Expect = 6e-05
Identities = 43/123 (34%), Positives = 48/123 (39%), Gaps = 8/123 (6%)
Query: 323 RGGGSGGGRRGRGGYRG--RGGFQGRGGDPKSGDWVCPNPSCGNMNFARRNSCNQCNEPR 380
RGGGS GG G G G GG G G SG S G + +
Sbjct: 464 RGGGSFGGGYGGGSSGGGSSGGGHGGGHGGSSGGGYGGGSSGGGSSGGGYGGGSSSGGHG 523
Query: 381 PEDSRPSGGDFRGRGYGGERGYRGRGGRGGDR-GGYGGDRSGGGYGGDRSSGGGYSGDRS 439
S GG G G GG G G G G GGYGG S GG+ +SS G G+ S
Sbjct: 524 GSSSGGYGGGSSGGGGGGYGG--GSSGGGSSSGGGYGGGSSSGGH---KSSSSGSVGESS 578
Query: 440 GGG 442
G
Sbjct: 579 SKG 581
Score = 38.5 bits (88), Expect = 0.017
Identities = 23/58 (39%), Positives = 28/58 (48%), Gaps = 2/58 (3%)
Query: 168 GEDNRGYGGSQGGGRGRGGYDKDGRGPMTGSSGGDRGGFKNFGGHRDYGPRTDADSES 225
G + GYGG GG G GGY G SSGG GG + GGH+ + +S S
Sbjct: 524 GSSSGGYGGGSSGG-GGGGYGGGSSGG-GSSSGGGYGGGSSSGGHKSSSSGSVGESSS 579
Score = 37.4 bits (85), Expect = 0.039
Identities = 25/68 (36%), Positives = 33/68 (48%), Gaps = 4/68 (5%)
Query: 2 SDSGSYG---QSGGEQQSYSTYGNPGSQGYGQASQSYSGYGQTTDSSYGQNYSGYSSYGQ 58
S GS G SGG + G+ G +G +S Y G G S+ +Y G SS+G
Sbjct: 38 SSKGSLGGGFSSGGFSGGSFSRGSSGGGCFGGSSGGYGGLGGFGGGSFRGSY-GSSSFGG 96
Query: 59 SYSQSYGG 66
SY S+GG
Sbjct: 97 SYGGSFGG 104
Score = 37.4 bits (85), Expect = 0.039
Identities = 21/45 (46%), Positives = 23/45 (51%), Gaps = 3/45 (6%)
Query: 168 GEDNRGYGGSQGGGRGRGGYDKDGRGPMTGSSGGDRGGFKNFGGH 212
G G+GG GG G GGY G GSSGG GG + GGH
Sbjct: 481 GSSGGGHGGGHGGSSG-GGYGGGSSG--GGSSGGGYGGGSSSGGH 522
Score = 36.6 bits (83), Expect = 0.066
Identities = 36/114 (31%), Positives = 39/114 (34%), Gaps = 7/114 (6%)
Query: 324 GGGSGGGRRGRGGYRGRGGFQGRG-GDPKSGDWVCPNPSCGNMNFARRNSCNQCNEPRPE 382
GG SGGG G G G GG G G G SG S G + + +
Sbjct: 475 GGSSGGGSSGGGHGGGHGGSSGGGYGGGSSGG----GSSGGGYGGGSSSGGHGGSSSGGY 530
Query: 383 DSRPSGGDFRGRGYGGERGYRGRGGR--GGDRGGYGGDRSGGGYGGDRSSGGGY 434
SGG G G G G GG GG G S G G S G Y
Sbjct: 531 GGGSSGGGGGGYGGGSSGGGSSSGGGYGGGSSSGGHKSSSSGSVGESSSKGPRY 584
Score = 35.8 bits (81), Expect = 0.11
Identities = 21/50 (42%), Positives = 25/50 (50%), Gaps = 3/50 (6%)
Query: 163 DVSRYGEDNRGYGGSQGGGRGRGGYDKDGRGPMTGSSGGDRGGFKNFGGH 212
++ Y G G S GGGRG G + G G GSSGG G + GGH
Sbjct: 445 EIQTYRSLLEGEGSSGGGGRGGGSF---GGGYGGGSSGGGSSGGGHGGGH 491
Score = 35.8 bits (81), Expect = 0.11
Identities = 27/98 (27%), Positives = 36/98 (36%), Gaps = 3/98 (3%)
Query: 5 GSYGQSGGEQQSYSTYGNPGSQGYGQASQSYSGYGQTTDSSYGQNYSGYSSYGQSYSQSY 64
G G SGG S+ G GYG S S G+G ++ YG SG G S
Sbjct: 490 GHGGSSGGGYGGGSSGGGSSGGGYGGGSSS-GGHGGSSSGGYGGGSSGGGGGGYGGGSSG 548
Query: 65 GGYENQKQSSYSQQPYNNQGQQQNMESSGSQGGRAPSY 102
GG + Y + + + S G + P Y
Sbjct: 549 GG--SSSGGGYGGGSSSGGHKSSSSGSVGESSSKGPRY 584
Score = 34.7 bits (78), Expect = 0.25
Identities = 27/84 (32%), Positives = 31/84 (36%), Gaps = 2/84 (2%)
Query: 168 GEDNRGYGG--SQGGGRGRGGYDKDGRGPMTGSSGGDRGGFKNFGGHRDYGPRTDADSES 225
G GYGG S GG G G G GSS G GG + GG YG + S
Sbjct: 493 GSSGGGYGGGSSGGGSSGGGYGGGSSSGGHGGSSSGGYGGGSSGGGGGGYGGGSSGGGSS 552
Query: 226 DNSDNNTIFVQGLGEGVSTDQVGE 249
G + S+ VGE
Sbjct: 553 SGGGYGGGSSSGGHKSSSSGSVGE 576
Score = 34.3 bits (77), Expect = 0.33
Identities = 31/124 (25%), Positives = 38/124 (30%), Gaps = 9/124 (7%)
Query: 8 GQSGGEQQSYSTYGNPGSQGYGQASQSYSGYGQTTDSSYGQNYSGYSSYGQSYSQSYGGY 67
G SGG + ++G G S G+G S G Y G SS G S YGG
Sbjct: 457 GSSGGGGRGGGSFGGGYGGGSSGGGSSGGGHGGGHGGSSGGGYGGGSSGGGSSGGGYGG- 515
Query: 68 ENQKQSSYSQQPYNNQGQQQNMESSGSQGGRAPSYDQPDYGQQDSYDQQSGYDQHQGSYD 127
+ G GS GG Y G S G G +
Sbjct: 516 --------GSSSGGHGGSSSGGYGGGSSGGGGGGYGGGSSGGGSSSGGGYGGGSSSGGHK 567
Query: 128 EQSN 131
S+
Sbjct: 568 SSSS 571
Score = 33.5 bits (75), Expect = 0.56
Identities = 19/45 (42%), Positives = 21/45 (46%), Gaps = 1/45 (2%)
Query: 168 GEDNRGYGGSQGGGRGRGGYDKDGR-GPMTGSSGGDRGGFKNFGG 211
G +GG GGG GG G G GSSGG GG + GG
Sbjct: 463 GRGGGSFGGGYGGGSSGGGSSGGGHGGGHGGSSGGGYGGGSSGGG 507
Score = 33.5 bits (75), Expect = 0.56
Identities = 20/45 (44%), Positives = 22/45 (48%), Gaps = 2/45 (4%)
Query: 168 GEDNRGYGGSQGGGRGRG--GYDKDGRGPMTGSSGGDRGGFKNFG 210
G G+GGS GGG G G G G G GSS G GG + G
Sbjct: 485 GGHGGGHGGSSGGGYGGGSSGGGSSGGGYGGGSSSGGHGGSSSGG 529
Score = 32.3 bits (72), Expect = 1.3
Identities = 21/49 (42%), Positives = 23/49 (46%), Gaps = 3/49 (6%)
Query: 168 GEDNRGYGGSQGGGRGRGGYDKDGRGPMTGSSGGDRGGFKNFGGHRDYG 216
GE + G GG +GGG GGY G GSSGG GG YG
Sbjct: 455 GEGSSG-GGGRGGGSFGGGYGGGSSGG--GSSGGGHGGGHGGSSGGGYG 500
Score = 32.3 bits (72), Expect = 1.3
Identities = 25/69 (36%), Positives = 26/69 (37%), Gaps = 5/69 (7%)
Query: 2 SDSGSYGQSGGEQQSYSTYGNPGSQGYGQASQS-----YSGYGQTTDSSYGQNYSGYSSY 56
S GS G G S +G S GYG S Y G SS G Y G SS
Sbjct: 504 SGGGSSGGGYGGGSSSGGHGGSSSGGYGGGSSGGGGGGYGGGSSGGGSSSGGGYGGGSSS 563
Query: 57 GQSYSQSYG 65
G S S G
Sbjct: 564 GGHKSSSSG 572
Score = 31.2 bits (69), Expect = 2.8
Identities = 21/47 (44%), Positives = 24/47 (51%), Gaps = 6/47 (12%)
Query: 167 YGEDNRGYGG--SQGGGRGRGGYDKDGRGPMTGSSGGDRGGFKNFGG 211
+G + GYGG GGG RG Y G GS GG GG +FGG
Sbjct: 67 FGGSSGGYGGLGGFGGGSFRGSY---GSSSFGGSYGGSFGG-GSFGG 109
Score = 30.4 bits (67), Expect = 4.8
Identities = 20/48 (41%), Positives = 21/48 (43%), Gaps = 1/48 (2%)
Query: 300 FDGKEFHGNIIKVSFATRRPEFMRGGGSGGGRRGRGGYRGRGGFQGRG 347
F G F G+ SF GG GGG G GG G GGF G G
Sbjct: 80 FGGGSFRGSYGSSSFGGSYGGSFGGGSFGGGSFG-GGSFGGGGFGGGG 126
>gi|109255251 loricrin [Homo sapiens]
Length = 312
Score = 120 bits (302), Expect = 3e-27
Identities = 109/306 (35%), Positives = 116/306 (37%), Gaps = 72/306 (23%)
Query: 321 FMRGGGSGGGRRGRG-GYRGRGGFQGRGGDPKSGDWVCPNPSCGNMNFARRNSCNQCNEP 379
F GGGSGGG G G GY G GG+ G G C S G C
Sbjct: 36 FFGGGGSGGGSSGSGCGYSGGGGYSGGG---------CGGGSSGGGGGGGIGGC------ 80
Query: 380 RPEDSRPSGGDFRGRGYGGERGYRGRGGRGGDRGGYGGDRSGGGYGGDRSSGGGYSGDRS 439
G G GG Y G GG G GG G SGGG G SSGGG S
Sbjct: 81 -------------GGGSGGSVKYSGGGGSSG--GGSGCFSSGGGGSGCFSSGGGGSSGGG 125
Query: 440 GGGY---GGDRSGGGYG--GDRGGGY---------------GGDRGGGYGGDRGGGYGGD 479
G + GG SGGG G GGG+ GG GGG G GG GG
Sbjct: 126 SGCFSSGGGGSSGGGSGCFSSGGGGFSGQAVQCQSYGGVSSGGSSGGGSGCFSSGGGGGS 185
Query: 480 RGGYGGDRGGGYGGDRGGYGGD--------------RGGYGGDRGGYGGDRGGYGGDRSR 525
GY G G GG GG G + YGG G GG G G S
Sbjct: 186 VCGYSGGGSGCGGGSSGGSGSGYVSSQQVTQTSCAPQPSYGGGSSGGGGSGGS--GCFSS 243
Query: 526 GGYGGDRGGGSGYGGDRSG---GYGGDRSGGGYGGDRGGGYGGDRGGYGGKMGGRNDYRN 582
GG GG G G G G SG GG GGG G GGG G GG G G ++
Sbjct: 244 GGGGGSSGCGGGSSGIGSGCIISGGGSVCGGGSSG--GGGGGSSVGGSGSGKGVPICHQT 301
Query: 583 DQRNRP 588
Q+ P
Sbjct: 302 QQKQAP 307
Score = 120 bits (300), Expect = 5e-27
Identities = 99/251 (39%), Positives = 106/251 (42%), Gaps = 56/251 (22%)
Query: 378 EPRPEDSRPSGGDFRGRGYGGER-GYRGRGGRGGDRGGYG-GDRSGGGYGGDRSSGGGYS 435
+P + + SGG G G GG G+ G GG GG G G G GGGY G GGG S
Sbjct: 11 QPPVDCVKTSGGGGGGGGSGGGGCGFFGGGGSGGGSSGSGCGYSGGGGYSGG-GCGGGSS 69
Query: 436 GDRSGGGYGGDRSGGGYGGD-RGGGYGGDRGGGYG--GDRGGGYGGDRGGYGGDRGGGYG 492
G GGG GG GGG GG + G GG GGG G GGG G G GG GGG G
Sbjct: 70 GGGGGGGIGG--CGGGSGGSVKYSGGGGSSGGGSGCFSSGGGGSGCFSSGGGGSSGGGSG 127
Query: 493 ----GDRGGYGGDRGGYGGDRGGY---------------GGDRGGYGGDRSRGGYGGD-- 531
G G GG G + GG+ GG GG G S GG GG
Sbjct: 128 CFSSGGGGSSGGGSGCFSSGGGGFSGQAVQCQSYGGVSSGGSSGGGSGCFSSGGGGGSVC 187
Query: 532 --RGGGSGYGGDRSGG---------------------YGGDRSGGGYGGDRG----GGYG 564
GGGSG GG SGG YGG SGGG G G GG G
Sbjct: 188 GYSGGGSGCGGGSSGGSGSGYVSSQQVTQTSCAPQPSYGGGSSGGGGSGGSGCFSSGGGG 247
Query: 565 GDRGGYGGKMG 575
G G GG G
Sbjct: 248 GSSGCGGGSSG 258
Score = 116 bits (290), Expect = 7e-26
Identities = 82/187 (43%), Positives = 85/187 (45%), Gaps = 30/187 (16%)
Query: 419 RSGGGYGGDRSSGGGYSGDRSGGGYGGDRSGGGYGGDRGGGY--GGDRGGGYGGDRGGGY 476
++ GG GG SGGG G GGG GG SG G G GGGY GG GG GG GGG
Sbjct: 18 KTSGGGGGGGGSGGGGCGFFGGGGSGGGSSGSGCGYSGGGGYSGGGCGGGSSGGGGGGGI 77
Query: 477 GGDRGGYGGD-----RGGGYGGDRGGYGGDRGGYGGDRGGYGGDRGGYGGDRSRGGYGGD 531
GG GG GG GG GG G + GG G G GG GG G S GG GG
Sbjct: 78 GGCGGGSGGSVKYSGGGGSSGGGSGCFSSGGGGSGCFSSGGGGSSGGGSGCFSSGG-GGS 136
Query: 532 RGGGSG------------------YGGDRSGGYGGDRSG----GGYGGDRGGGYGGDRGG 569
GGGSG YGG SGG G SG GG GG G GG G
Sbjct: 137 SGGGSGCFSSGGGGFSGQAVQCQSYGGVSSGGSSGGGSGCFSSGGGGGSVCGYSGGGSGC 196
Query: 570 YGGKMGG 576
GG GG
Sbjct: 197 GGGSSGG 203
Score = 112 bits (279), Expect = 1e-24
Identities = 87/185 (47%), Positives = 89/185 (48%), Gaps = 25/185 (13%)
Query: 407 GRGGDRGGYGGDRSGGGYGGDRSSGGGYSGDRSGGGYGGDRSGGGY-GGDRGGGYGGDRG 465
G GG GG GG G G+ G SGGG SG SG GY G GGGY GG GGG G G
Sbjct: 21 GGGGGGGGSGG--GGCGFFGGGGSGGGSSG--SGCGYSG---GGGYSGGGCGGGSSGGGG 73
Query: 466 GGYGGDRGGGYGGDRGGYGGDRGGGYGGDRGGYGGDRGGYGGDRGGYGGDRGGYGGDRSR 525
GG G GGG GG GG GG GG G + GG G G GG GG G S
Sbjct: 74 GGGIGGCGGGSGGSVKYSGG--GGSSGGGSGCFSSGGGGSGCFSSGGGGSSGGGSGCFSS 131
Query: 526 GGYGGDRGGGSGY----GGDRSG------GYGGDRSGGGYGGDRG----GGYGGDRGGYG 571
GG GG GGGSG GG SG YGG SGG GG G GG GG GY
Sbjct: 132 GG-GGSSGGGSGCFSSGGGGFSGQAVQCQSYGGVSSGGSSGGGSGCFSSGGGGGSVCGYS 190
Query: 572 GKMGG 576
G G
Sbjct: 191 GGGSG 195
Score = 61.2 bits (147), Expect = 3e-09
Identities = 38/78 (48%), Positives = 39/78 (50%), Gaps = 8/78 (10%)
Query: 503 GGYGGDRGGYGGDRGGYGGDRSRGGYGGDRGGGSGYGGDRSGGYGGDRSGGGYGGDRGGG 562
GG GG G GG G +GG G GG G G GY G GGY G GG GG GGG
Sbjct: 21 GGGGGGGGSGGGGCGFFGGG---GSGGGSSGSGCGYSG--GGGYSG---GGCGGGSSGGG 72
Query: 563 YGGDRGGYGGKMGGRNDY 580
GG GG GG GG Y
Sbjct: 73 GGGGIGGCGGGSGGSVKY 90
Score = 61.2 bits (147), Expect = 3e-09
Identities = 84/291 (28%), Positives = 95/291 (32%), Gaps = 26/291 (8%)
Query: 175 GGSQGGGRGRGGYDKDGRGPMTGSSGGDRGGFKNFGGHRDYGPRTDADSESDNSDNNTIF 234
GG GGG G GG G G G S G G+ GG+ G S I
Sbjct: 22 GGGGGGGSGGGGCGFFGGGGSGGGSSGSGCGYSGGGGYSGGG---CGGGSSGGGGGGGIG 78
Query: 235 VQGLGEGVSTDQVGEFFKQIGIIKTNKKTGKPMINLYTDKDTGKPKGEATVSFDDPPSAK 294
G G G S G G G + G S S+
Sbjct: 79 GCGGGSGGSVKYSGGGGSSGGGSGCFSSGGGGSGCFSSGGGGSSGGGSGCFSSGGGGSSG 138
Query: 295 AAIDWFD--GKEFHGNIIKV-SFATRRPEFMRGGG-----SGGGRRGRGGYRGRGGFQGR 346
F G F G ++ S+ GGG SGGG GY G G G
Sbjct: 139 GGSGCFSSGGGGFSGQAVQCQSYGGVSSGGSSGGGSGCFSSGGGGGSVCGYSGGGSGCGG 198
Query: 347 GGDPKSGDWVCPNPSCGNMNFARRNSCNQCNEPRPEDSRPSGGDFRGRGYGGERGYRGRG 406
G SG + + SC P+P GG G G G G G
Sbjct: 199 GSSGGSGSGYVSSQQ------VTQTSC----APQPS----YGGGSSGGGGSGGSGCFSSG 244
Query: 407 GRGGDRGGYGGDRSGGGYGGDRSSGGGYSGDRSGGGYGGDRSGGGYGGDRG 457
G GG G GG SG G G S GG G S GG GG S GG G +G
Sbjct: 245 G-GGGSSGCGGGSSGIGSGCIISGGGSVCGGGSSGGGGGGSSVGGSGSGKG 294
Score = 37.7 bits (86), Expect = 0.030
Identities = 69/255 (27%), Positives = 86/255 (33%), Gaps = 56/255 (21%)
Query: 173 GYGGSQGGGRGRGGYDKDGRGPMT----GSSGGDRGGFKNFGGHRDYGPRTDADSESDNS 228
G GGS GGG G G G + GSSGG G F + GG G S
Sbjct: 92 GGGGSSGGGSGCFSSGGGGSGCFSSGGGGSSGGGSGCFSSGGGGSSGGGSGCFSSGGGGF 151
Query: 229 DNNTIFVQGLGEGVSTDQVGEFFKQIGIIKTNKKTGKPMINLYTDKDTGKPKGEATVSFD 288
+ Q G GVS+ G G + G + Y+ +G G + S
Sbjct: 152 SGQAVQCQSYG-GVSSG--GSSGGGSGCFSSGGGGGS--VCGYSGGGSGCGGGSSGGSGS 206
Query: 289 DPPSAKAAIDWFDGKEFHGNIIKVSFATRRPEFMRGGGSGGGRRGRGGYRGRGGFQGRGG 348
S++ +V+ + P+ GGGS GG GG G G F GG
Sbjct: 207 GYVSSQ----------------QVTQTSCAPQPSYGGGSSGG----GGSGGSGCFSSGGG 246
Query: 349 DPKSGDWVCPNPSCGNMNFARRNSCNQCNEPRPEDSRPSGGDFRGRGYGGERGYRGRGGR 408
SG CG + + C SGG G GG G G
Sbjct: 247 GGSSG--------CGGGSSGIGSGC-----------IISGG---GSVCGG-----GSSGG 279
Query: 409 GGDRGGYGGDRSGGG 423
GG GG SG G
Sbjct: 280 GGGGSSVGGSGSGKG 294
Score = 36.6 bits (83), Expect = 0.066
Identities = 54/204 (26%), Positives = 64/204 (31%), Gaps = 39/204 (19%)
Query: 4 SGSYGQSGGEQQSYSTYGNPGSQGYGQASQSYSGYGQTTDSSYGQNYSGYSSYGQSYSQS 63
SG G SGG +S+ G GS + SG G SS G SG S +S
Sbjct: 91 SGGGGSSGGGSGCFSS-GGGGSGCFSSGGGGSSGGGSGCFSSGGGGSSGGGS--GCFSSG 147
Query: 64 YGGYENQK---QSSYSQQPYNNQGQQQNMESSGSQGGRAPSYDQPDYGQQDSYDQQSGYD 120
GG+ Q QS + G SSG GG Y G SG
Sbjct: 148 GGGFSGQAVQCQSYGGVSSGGSSGGGSGCFSSGGGGGSVCGYSGGGSGCGGGSSGGSG-- 205
Query: 121 QHQGSYDEQSNYDQQHDSYSQNQQSYHSQRENYSHHTQDDRRDVSRYGEDNRGYGGSQGG 180
Y +QQ TQ YG + G GGS G
Sbjct: 206 ----------------SGYVSSQQV-----------TQTSCAPQPSYGGGSSGGGGSGGS 238
Query: 181 GRGRGGYDKDGRGPMTGSSGGDRG 204
G + G G +G GG G
Sbjct: 239 ----GCFSSGGGGGSSGCGGGSSG 258
>gi|109452587 family with sequence similarity 98, member B isoform 1
[Homo sapiens]
Length = 433
Score = 116 bits (290), Expect = 7e-26
Identities = 68/107 (63%), Positives = 71/107 (66%), Gaps = 8/107 (7%)
Query: 449 GGGYGGDRGGGYGGDRGGGYGGDRGGGYGGDRGGYGGDRGGGYGGDRGGYGGDRGGYGGD 508
GGG GG GGG GG RGGG GG GG+GG GG+GG GGG GG GG GG RGG+ G
Sbjct: 332 GGGRGGWGGGGGGGGRGGGGGGGGRGGWGGGGGGWGGGGGGG-GGWGGGGGGGRGGFQG- 389
Query: 509 RGGYGGDRGGYGGDRSRGGYGGDRGGGSGYGGDRSGGYGGDRSGGGY 555
RG YGG RGGYGG RGGYGG RG G YGG GG GG GGGY
Sbjct: 390 RGDYGG-RGGYGG---RGGYGG-RGYGDPYGGGGGGG-GGGGGGGGY 430
Score = 111 bits (278), Expect = 2e-24
Identities = 66/109 (60%), Positives = 70/109 (64%), Gaps = 7/109 (6%)
Query: 438 RSGGGYGGDRSGGGYGGDRGGGYGGDRGGGYGGDRGGGYGGDRGGYGGDRGGGYGGDRGG 497
+ GGG G GGG GG RGGG GG GG+GG GGG+GG GG GG GGG GG RGG
Sbjct: 329 QEGGGGRGGWGGGGGGGGRGGGGGGGGRGGWGGG-GGGWGGGGGG-GGGWGGGGGGGRGG 386
Query: 498 YGGDRGGYGGDRGGYGGDRGGYGGDRSRGGYGGDRGGGSGYGGDRSGGY 546
+ G RG YGG RGGYGG RGGYGG YGG GGG G GG GGY
Sbjct: 387 FQG-RGDYGG-RGGYGG-RGGYGGRGYGDPYGG--GGGGGGGGGGGGGY 430
Score = 105 bits (263), Expect = 9e-23
Identities = 74/130 (56%), Positives = 78/130 (60%), Gaps = 31/130 (23%)
Query: 409 GGDRGGYGGDRSGGGYGGDRSSGGGYSGDRSGGGYGGDRSGGGYGGDRGGGYGGDRGGGY 468
GG RGG+GG GGG GG R GGG GG R GG+GG GGG+GG GGG
Sbjct: 332 GGGRGGWGG---GGGGGG-----------RGGGGGGGGR--GGWGGG-GGGWGG--GGGG 372
Query: 469 GGDRGGGYGGDRGGYGGDRGGGYGGDRGGYGGDRGGYGGDRGGYGGDRGGYGGDRSRGGY 528
GG GGG GG RGG+ G G YGG RGGYGG RGGYGG GYG GG GG GG
Sbjct: 373 GGGWGGGGGGGRGGFQG--RGDYGG-RGGYGG-RGGYGG--RGYGDPYGGGGG----GGG 422
Query: 529 GGDRGGGSGY 538
GG GGG GY
Sbjct: 423 GG--GGGGGY 430
Score = 103 bits (258), Expect = 3e-22
Identities = 59/105 (56%), Positives = 61/105 (58%), Gaps = 8/105 (7%)
Query: 465 GGGYGGDRGGGYGGDRGGYGGDRGGGYGGDRGGYGGDRGGYGGDRGGYGGDRGGYGGDRS 524
GGG GG GGG GG RGG GG GG RGG+GG GG+GG GG GG GG GG R
Sbjct: 332 GGGRGGWGGGGGGGGRGGGGG------GGGRGGWGGGGGGWGGGGGGGGGWGGGGGGGRG 385
Query: 525 RGGYGGDRGGGSGYGGDRSGGYGGDRSGGGYGGDRGGGYGGDRGG 569
GD GG GYGG GGYGG G YGG GGG GG GG
Sbjct: 386 GFQGRGDYGGRGGYGG--RGGYGGRGYGDPYGGGGGGGGGGGGGG 428
Score = 101 bits (251), Expect = 2e-21
Identities = 67/130 (51%), Positives = 72/130 (55%), Gaps = 17/130 (13%)
Query: 374 NQCNEPRPE----DSRPSGGDFRGR-GYGGERGYRGRGGRGGDRGGYGGDRSGGGYGGDR 428
N+ P PE R GG RG G GG G RG GG GG RGG+GG GGG+GG
Sbjct: 313 NEIEPPPPEMPPWQKRQEGGGGRGGWGGGGGGGGRGGGGGGGGRGGWGG--GGGGWGGGG 370
Query: 429 SSGGGYSGDRSGGGYGGDRSGGGYGGDRGGGYGGDRGGGYGGDRGGGYGGDRGGYGGDRG 488
GGG+ G GGG GG + G YGG GGYGG GGYG G GYG GG GG G
Sbjct: 371 GGGGGWGGG-GGGGRGGFQGRGDYGG--RGGYGG--RGGYG---GRGYGDPYGGGGG--G 420
Query: 489 GGYGGDRGGY 498
GG GG GGY
Sbjct: 421 GGGGGGGGGY 430
Score = 100 bits (249), Expect = 4e-21
Identities = 72/136 (52%), Positives = 77/136 (56%), Gaps = 22/136 (16%)
Query: 378 EPRPEDSRPSGGDFRGRGYGGERGYRGRGGRGGDRGGYGGDRSGGGYGGDRSSGGGYSGD 437
EP P + P R G GG G+ G GG GG RGG GG GGG GG GGG+
Sbjct: 316 EPPPPEMPP--WQKRQEGGGGRGGWGGGGGGGG-RGGGGG---GGGRGGWGGGGGGW--- 366
Query: 438 RSGGGYGGDRSGGGYGGDRGGGYGGDRG-GGYGGDRGGGYGGDRGGYGGDRGGGYGGDRG 496
GGG GG GGG+GG GGG GG +G G YGG GGYGG RGGYG G GYG G
Sbjct: 367 --GGGGGG---GGGWGGGGGGGRGGFQGRGDYGG--RGGYGG-RGGYG---GRGYGDPYG 415
Query: 497 GYGGDRGGYGGDRGGY 512
G GG GG GG GGY
Sbjct: 416 G-GGGGGGGGGGGGGY 430
Score = 92.0 bits (227), Expect = 1e-18
Identities = 48/82 (58%), Positives = 54/82 (65%), Gaps = 5/82 (6%)
Query: 492 GGDRGGYGGDRGGYGGDRGGYGGDRGGYGGDRSRGGYGGDRGGGSGYGGDRSGGYGGDRS 551
GG RGG+GG GG G GG GG RGG+GG GG+GG GGG G+GG GG GG +
Sbjct: 332 GGGRGGWGGGGGGGGRGGGGGGGGRGGWGG--GGGGWGGGGGGGGGWGGGGGGGRGGFQG 389
Query: 552 GGGYGGDRGGGYGGDRGGYGGK 573
G YGG GGYGG RGGYGG+
Sbjct: 390 RGDYGGR--GGYGG-RGGYGGR 408
Score = 84.0 bits (206), Expect = 4e-16
Identities = 46/77 (59%), Positives = 51/77 (66%), Gaps = 4/77 (5%)
Query: 499 GGDRGGYGGDRGGYGGDRGGYGGDRSRGGYGGDRGGGSGYGGDRSGGYGGDRSGGGYGGD 558
GG RGG+GG GG GG RGG GG RGG+GG GGG G GG GG+GG GGG GG
Sbjct: 332 GGGRGGWGG--GGGGGGRGGGGGGGGRGGWGGG-GGGWGGGGGGGGGWGGG-GGGGRGGF 387
Query: 559 RGGGYGGDRGGYGGKMG 575
+G G G RGGYGG+ G
Sbjct: 388 QGRGDYGGRGGYGGRGG 404
Score = 77.0 bits (188), Expect = 4e-14
Identities = 56/133 (42%), Positives = 60/133 (45%), Gaps = 41/133 (30%)
Query: 324 GGGSGGGRRGRGGYRGRGGFQGRGGDPKSGDWVCPNPSCGNMNFARRNSCNQCNEPRPED 383
GGG GGGR G GG GRGG+ G GG G
Sbjct: 340 GGGGGGGRGGGGGGGGRGGWGGGGGGWGGGG----------------------------- 370
Query: 384 SRPSGGDFRGRGYGGERGYRGRGGRGGDRGGYGGDRSGGGYGGDRSSGGGYSGDRSGGGY 443
GG + G G GG G++GRG GG RGGYGG GGYG G GY GD GGG
Sbjct: 371 --GGGGGWGGGGGGGRGGFQGRGDYGG-RGGYGG---RGGYG-----GRGY-GDPYGGGG 418
Query: 444 GGDRSGGGYGGDR 456
GG GGG GG R
Sbjct: 419 GGGGGGGGGGGYR 431
Score = 76.3 bits (186), Expect = 8e-14
Identities = 57/150 (38%), Positives = 60/150 (40%), Gaps = 42/150 (28%)
Query: 319 PEFMRGGGSGGGRRGRGGYRGRGGFQGRGGDPKSGDWVCPNPSCGNMNFARRNSCNQCNE 378
P + + GGGR G GG G GG G GG G W
Sbjct: 323 PPWQKRQEGGGGRGGWGGGGGGGGRGGGGGGGGRGGW----------------------- 359
Query: 379 PRPEDSRPSGGDFRGRGYGGERGYRGRGGRGGDRGGYGGDRSGGGYGGDRSSGGGYSGDR 438
GG G G+GG G GG GG GG GG R G GD GGY G
Sbjct: 360 --------GGG---GGGWGG-----GGGGGGGWGGGGGGGRGGFQGRGDYGGRGGYGG-- 401
Query: 439 SGGGYGGDRSGGGYGGDRGGGYGGDRGGGY 468
GGYGG G YGG GGG GG GGGY
Sbjct: 402 -RGGYGGRGYGDPYGGGGGGGGGGGGGGGY 430
Score = 70.9 bits (172), Expect = 3e-12
Identities = 38/68 (55%), Positives = 41/68 (60%), Gaps = 6/68 (8%)
Query: 513 GGDRGGYGGDRSRGGYGGDRGGGSGYGGDRSGGYGGDRSGGGYGGDRGGGYGGDRGGYGG 572
GG RGG+GG GG GG RGGG G GG GG+GG G G GG GGG+GG GG G
Sbjct: 332 GGGRGGWGG----GGGGGGRGGGGGGGG--RGGWGGGGGGWGGGGGGGGGWGGGGGGGRG 385
Query: 573 KMGGRNDY 580
GR DY
Sbjct: 386 GFQGRGDY 393
Score = 42.0 bits (97), Expect = 0.002
Identities = 24/56 (42%), Positives = 27/56 (48%), Gaps = 2/56 (3%)
Query: 167 YGEDNRGYGGSQGGGRGRGGYDKDGRGPMTGSSGGDRGGFKNFGGHRDYGPRTDAD 222
+G G+GG GGG G GG GRG G GD GG +GG YG R D
Sbjct: 359 WGGGGGGWGGGGGGGGGWGGGGGGGRGGFQGR--GDYGGRGGYGGRGGYGGRGYGD 412
Score = 42.0 bits (97), Expect = 0.002
Identities = 23/50 (46%), Positives = 25/50 (50%)
Query: 166 RYGEDNRGYGGSQGGGRGRGGYDKDGRGPMTGSSGGDRGGFKNFGGHRDY 215
R G RG G +GG GRGGY G G G GG GG GG+R Y
Sbjct: 384 RGGFQGRGDYGGRGGYGGRGGYGGRGYGDPYGGGGGGGGGGGGGGGYRRY 433
Score = 39.3 bits (90), Expect = 0.010
Identities = 24/54 (44%), Positives = 27/54 (50%), Gaps = 6/54 (11%)
Query: 168 GEDNRGYGGSQGGGRGRGGYDKDGRGPMTGSSGGDRGGFK---NFGGHRDYGPR 218
G RG G GGG G GG G G G GG RGGF+ ++GG YG R
Sbjct: 352 GGGGRGGWGGGGGGWGGGG---GGGGGWGGGGGGGRGGFQGRGDYGGRGGYGGR 402
Score = 37.4 bits (85), Expect = 0.039
Identities = 22/51 (43%), Positives = 23/51 (45%)
Query: 168 GEDNRGYGGSQGGGRGRGGYDKDGRGPMTGSSGGDRGGFKNFGGHRDYGPR 218
G G GG +GG G GG G G G GG GG F G DYG R
Sbjct: 346 GRGGGGGGGGRGGWGGGGGGWGGGGGGGGGWGGGGGGGRGGFQGRGDYGGR 396
Score = 31.2 bits (69), Expect = 2.8
Identities = 17/43 (39%), Positives = 20/43 (46%)
Query: 169 EDNRGYGGSQGGGRGRGGYDKDGRGPMTGSSGGDRGGFKNFGG 211
++ G G GGG G GG G G G GG GG+ GG
Sbjct: 329 QEGGGGRGGWGGGGGGGGRGGGGGGGGRGGWGGGGGGWGGGGG 371
>gi|14043072 heterogeneous nuclear ribonucleoprotein A2/B1 isoform
B1 [Homo sapiens]
Length = 353
Score = 114 bits (286), Expect = 2e-25
Identities = 111/321 (34%), Positives = 135/321 (42%), Gaps = 90/321 (28%)
Query: 233 IFVQGLGEGVSTDQVGEFFKQIGIIKTNKKTGKPMINLYTDKDTGKPKGEATVSFDD-PP 291
+FV G+ E + ++F++ G I T I + TD+ +GK +G V+FDD P
Sbjct: 114 LFVGGIKEDTEEHHLRDYFEEYGKIDT--------IEIITDRQSGKKRGFGFVTFDDHDP 165
Query: 292 SAKAAIDWFDGKEFHGNIIKVSFATRRPEFMRGGGSGGGRRGRGGYRGRGGFQGRGGDPK 351
K + + +G+ +V A R E S R GRG
Sbjct: 166 VDKIVLQKYH--TINGHNAEVRKALSRQEMQEVQSS---RSGRG---------------- 204
Query: 352 SGDWVCPNPSCGNMNFARRNSCNQCNEPRPEDSRPSGGDFRGRGYGGERGYRGRGGRGGD 411
GN F DSR GG+F G G
Sbjct: 205 -----------GNFGFG--------------DSRGGGGNF------------GPGPGSNF 227
Query: 412 RGGYGGDRSGGGYGGDRSSGGGYSGDRSGGGYGGDRSGG--GYGGDRGGGYGGDRGGGYG 469
RGG GYG R G GY+G GGG GG GG GYGG R GGYGG G GY
Sbjct: 228 RGG------SDGYGSGRGFGDGYNG--YGGGPGGGNFGGSPGYGGGR-GGYGGG-GPGY- 276
Query: 470 GDRGGGYGGDRGGYGGDRGGGYGGDRGGYGGDRGGYGGDRGGYGGDR-GGYGGDRSRGG- 527
G++GGGYGG YG GG YG G Y D G Y YG + G +GG R+ GG
Sbjct: 277 GNQGGGYGGGYDNYG---GGNYGS--GNY-NDFGNYNQQPSNYGPMKSGNFGGSRNMGGP 330
Query: 528 YGGDRGGGSGYGGDRSGGYGG 548
YGG G G GG SGGYGG
Sbjct: 331 YGGGNYGPGGSGG--SGGYGG 349
Score = 114 bits (286), Expect = 2e-25
Identities = 70/156 (44%), Positives = 77/156 (49%), Gaps = 12/156 (7%)
Query: 421 GGGYG-GDRSSGGGYSGDRSGGGYGGDRSGGGYGGDRGGGYGGDRGGGYGGDRGGGYGGD 479
GG +G GD GGG G G + G G G G G GY G YGG GGG G
Sbjct: 204 GGNFGFGDSRGGGGNFGPGPGSNFRGGSDGYGSGRGFGDGYNG-----YGGGPGGGNFGG 258
Query: 480 RGGYGGDRGGGYGGDRGGYGGDRGGYGGDRGGYGGDRGGYGGDRSRGGYGGDRGGGSGYG 539
GYGG R GGYGG GYG GGYGG YGG G G G Y S YG
Sbjct: 259 SPGYGGGR-GGYGGGGPGYGNQGGGYGGGYDNYGGGNYGSGNYNDFGNYNQQ---PSNYG 314
Query: 540 GDRSGGYGGDRSGGG--YGGDRGGGYGGDRGGYGGK 573
+SG +GG R+ GG GG+ G G G GGYGG+
Sbjct: 315 PMKSGNFGGSRNMGGPYGGGNYGPGGSGGSGGYGGR 350
Score = 108 bits (271), Expect = 1e-23
Identities = 74/158 (46%), Positives = 82/158 (51%), Gaps = 13/158 (8%)
Query: 405 RGGRGGDRGGYGGDRSGGGYGGDRSSGGGYSGDRSGGGYGGDRS-GGGYGGDRGGGYGGD 463
R GRGG+ G +G R GGG G G G + GYG R G GY G GG GG+
Sbjct: 200 RSGRGGNFG-FGDSRGGGGNFGP---GPGSNFRGGSDGYGSGRGFGDGYNGYGGGPGGGN 255
Query: 464 RGG--GYGGDRGGGYGGDRGGYGGDRGGGYGGDRGGYGGDRGGYG--GDRGGYGGDRGGY 519
GG GYGG RGG YGG GY G++GGGYGG YGG G G D G Y Y
Sbjct: 256 FGGSPGYGGGRGG-YGGGGPGY-GNQGGGYGGGYDNYGGGNYGSGNYNDFGNYNQQPSNY 313
Query: 520 GGDRSRGGYGGDRGGGSGYGGDRSGGYGGDRSGGGYGG 557
G +S G +GG R G YGG G GG GGYGG
Sbjct: 314 GPMKS-GNFGGSRNMGGPYGGGNYGP-GGSGGSGGYGG 349
Score = 82.0 bits (201), Expect = 1e-15
Identities = 53/112 (47%), Positives = 63/112 (56%), Gaps = 13/112 (11%)
Query: 472 RGGGYG-GDRGGYGGDRGGGYGGDRGGYGGDRGGYGGDRGGYGGDRGGYGGDRSRGGYGG 530
RGG +G GD G GG+ G G G + + G GYG RG +G GYGG G GG
Sbjct: 203 RGGNFGFGDSRGGGGNFGPGPGSN---FRGGSDGYGSGRG-FGDGYNGYGG----GPGGG 254
Query: 531 DRGGGSGYGGDRSGGYGGDRSGGGYGGDRGGGYGGDRGGYGGKMGGRNDYRN 582
+ GG GYGG R GGYGG G GYG ++GGGYGG YGG G +Y +
Sbjct: 255 NFGGSPGYGGGR-GGYGG--GGPGYG-NQGGGYGGGYDNYGGGNYGSGNYND 302
Score = 56.6 bits (135), Expect = 6e-08
Identities = 45/169 (26%), Positives = 60/169 (35%), Gaps = 18/169 (10%)
Query: 18 STYGNPGSQGYGQASQSYSGYGQTTDSSYGQNYSGYSSYGQSYSQSYGGYENQKQSSYSQ 77
S G G+ G+G + +G S++ GY S G+ + Y GY
Sbjct: 199 SRSGRGGNFGFGDSRGGGGNFGPGPGSNFRGGSDGYGS-GRGFGDGYNGYGGGPGGG--- 254
Query: 78 QPYNNQGQQQNMESSGSQGGRAPSYDQPDYGQQDSYDQQSGYDQHQGSYDEQSNYDQQHD 137
N G G GG P Y G YD G + G+Y++ NY+QQ
Sbjct: 255 ---NFGGSPGYGGGRGGYGGGGPGYGNQGGGYGGGYDNYGGGNYGSGNYNDFGNYNQQPS 311
Query: 138 SYSQNQQSYHSQRENYSHHTQDDRRDVSRYGEDNRGYGGSQGGGRGRGG 186
+Y + N YG N G GGS GG G GG
Sbjct: 312 NYGPMKSGNFGGSRNMG----------GPYGGGNYGPGGS-GGSGGYGG 349
Score = 45.4 bits (106), Expect = 1e-04
Identities = 39/128 (30%), Positives = 47/128 (36%), Gaps = 17/128 (13%)
Query: 4 SGSYGQSGGEQQSYSTYGN-------PGSQGYGQASQSYSGYGQ---TTDSSYGQNYSGY 53
S YG G Y+ YG GS GYG Y G G YG Y Y
Sbjct: 231 SDGYGSGRGFGDGYNGYGGGPGGGNFGGSPGYGGGRGGYGGGGPGYGNQGGGYGGGYDNY 290
Query: 54 --SSYGQSYSQSYGGYENQKQSSYSQQPYNNQGQQQNMESSGSQGGRAPSYDQPDYGQQD 111
+YG +G Y NQ+ S+Y N G +NM G GG +Y G
Sbjct: 291 GGGNYGSGNYNDFGNY-NQQPSNYGPMKSGNFGGSRNM--GGPYGG--GNYGPGGSGGSG 345
Query: 112 SYDQQSGY 119
Y +S Y
Sbjct: 346 GYGGRSRY 353
Score = 42.0 bits (97), Expect = 0.002
Identities = 24/55 (43%), Positives = 29/55 (52%), Gaps = 12/55 (21%)
Query: 167 YGEDNRGYGGSQGGGR---------GRGGYDKDGRGPMTGSSGGD-RGGFKNFGG 211
+G+ GYGG GGG GRGGY G GP G+ GG GG+ N+GG
Sbjct: 240 FGDGYNGYGGGPGGGNFGGSPGYGGGRGGYG--GGGPGYGNQGGGYGGGYDNYGG 292
Score = 33.9 bits (76), Expect = 0.43
Identities = 65/266 (24%), Positives = 88/266 (33%), Gaps = 74/266 (27%)
Query: 106 DYGQQDSY----DQQSGYDQHQG--SYDEQSNYDQQHDSYSQNQQSYHS-QRENYSHHTQ 158
+YG+ D+ D+QSG + G ++D+ D+ Q YH+ N
Sbjct: 134 EYGKIDTIEIITDRQSGKKRGFGFVTFDDHDPVDKIV------LQKYHTINGHNAEVRKA 187
Query: 159 DDRRDVSRYGEDNRGYGGSQGGGRGRGGYDKDGRGPMTGSSGGDRG-------------- 204
R+++ G GG+ G G RGG G GP + GG G
Sbjct: 188 LSRQEMQEVQSSRSGRGGNFGFGDSRGGGGNFGPGPGSNFRGGSDGYGSGRGFGDGYNGY 247
Query: 205 ----GFKNFGGHRDYGPRTDADSESDNSDNNTIFVQGLGEGVSTDQVGEFFKQIGIIKTN 260
G NFGG YG N QG G G D G N
Sbjct: 248 GGGPGGGNFGGSPGYGGGRGGYGGGGPGYGN----QGGGYGGGYDNYG---------GGN 294
Query: 261 KKTGKPMINLYTDKDTGKPKGEATVSFDDPPSAKAAIDWFDGKEFHGNIIKVSFATRRPE 320
+G Y D +++ PS +G + +F R
Sbjct: 295 YGSGN-----YNDFG----------NYNQQPSN------------YGPMKSGNFGGSR-- 325
Query: 321 FMRGGGSGGGRRGRGGYRGRGGFQGR 346
GG GGG G GG G GG+ GR
Sbjct: 326 -NMGGPYGGGNYGPGGSGGSGGYGGR 350
>gi|4504447 heterogeneous nuclear ribonucleoprotein A2/B1 isoform A2
[Homo sapiens]
Length = 341
Score = 114 bits (286), Expect = 2e-25
Identities = 111/321 (34%), Positives = 135/321 (42%), Gaps = 90/321 (28%)
Query: 233 IFVQGLGEGVSTDQVGEFFKQIGIIKTNKKTGKPMINLYTDKDTGKPKGEATVSFDD-PP 291
+FV G+ E + ++F++ G I T I + TD+ +GK +G V+FDD P
Sbjct: 102 LFVGGIKEDTEEHHLRDYFEEYGKIDT--------IEIITDRQSGKKRGFGFVTFDDHDP 153
Query: 292 SAKAAIDWFDGKEFHGNIIKVSFATRRPEFMRGGGSGGGRRGRGGYRGRGGFQGRGGDPK 351
K + + +G+ +V A R E S R GRG
Sbjct: 154 VDKIVLQKYH--TINGHNAEVRKALSRQEMQEVQSS---RSGRG---------------- 192
Query: 352 SGDWVCPNPSCGNMNFARRNSCNQCNEPRPEDSRPSGGDFRGRGYGGERGYRGRGGRGGD 411
GN F DSR GG+F G G
Sbjct: 193 -----------GNFGFG--------------DSRGGGGNF------------GPGPGSNF 215
Query: 412 RGGYGGDRSGGGYGGDRSSGGGYSGDRSGGGYGGDRSGG--GYGGDRGGGYGGDRGGGYG 469
RGG GYG R G GY+G GGG GG GG GYGG R GGYGG G GY
Sbjct: 216 RGG------SDGYGSGRGFGDGYNG--YGGGPGGGNFGGSPGYGGGR-GGYGGG-GPGY- 264
Query: 470 GDRGGGYGGDRGGYGGDRGGGYGGDRGGYGGDRGGYGGDRGGYGGDR-GGYGGDRSRGG- 527
G++GGGYGG YG GG YG G Y D G Y YG + G +GG R+ GG
Sbjct: 265 GNQGGGYGGGYDNYG---GGNYGS--GNY-NDFGNYNQQPSNYGPMKSGNFGGSRNMGGP 318
Query: 528 YGGDRGGGSGYGGDRSGGYGG 548
YGG G G GG SGGYGG
Sbjct: 319 YGGGNYGPGGSGG--SGGYGG 337
Score = 114 bits (286), Expect = 2e-25
Identities = 70/156 (44%), Positives = 77/156 (49%), Gaps = 12/156 (7%)
Query: 421 GGGYG-GDRSSGGGYSGDRSGGGYGGDRSGGGYGGDRGGGYGGDRGGGYGGDRGGGYGGD 479
GG +G GD GGG G G + G G G G G GY G YGG GGG G
Sbjct: 192 GGNFGFGDSRGGGGNFGPGPGSNFRGGSDGYGSGRGFGDGYNG-----YGGGPGGGNFGG 246
Query: 480 RGGYGGDRGGGYGGDRGGYGGDRGGYGGDRGGYGGDRGGYGGDRSRGGYGGDRGGGSGYG 539
GYGG R GGYGG GYG GGYGG YGG G G G Y S YG
Sbjct: 247 SPGYGGGR-GGYGGGGPGYGNQGGGYGGGYDNYGGGNYGSGNYNDFGNYNQQ---PSNYG 302
Query: 540 GDRSGGYGGDRSGGG--YGGDRGGGYGGDRGGYGGK 573
+SG +GG R+ GG GG+ G G G GGYGG+
Sbjct: 303 PMKSGNFGGSRNMGGPYGGGNYGPGGSGGSGGYGGR 338
Score = 108 bits (271), Expect = 1e-23
Identities = 74/158 (46%), Positives = 82/158 (51%), Gaps = 13/158 (8%)
Query: 405 RGGRGGDRGGYGGDRSGGGYGGDRSSGGGYSGDRSGGGYGGDRS-GGGYGGDRGGGYGGD 463
R GRGG+ G +G R GGG G G G + GYG R G GY G GG GG+
Sbjct: 188 RSGRGGNFG-FGDSRGGGGNFGP---GPGSNFRGGSDGYGSGRGFGDGYNGYGGGPGGGN 243
Query: 464 RGG--GYGGDRGGGYGGDRGGYGGDRGGGYGGDRGGYGGDRGGYG--GDRGGYGGDRGGY 519
GG GYGG RGG YGG GY G++GGGYGG YGG G G D G Y Y
Sbjct: 244 FGGSPGYGGGRGG-YGGGGPGY-GNQGGGYGGGYDNYGGGNYGSGNYNDFGNYNQQPSNY 301
Query: 520 GGDRSRGGYGGDRGGGSGYGGDRSGGYGGDRSGGGYGG 557
G +S G +GG R G YGG G GG GGYGG
Sbjct: 302 GPMKS-GNFGGSRNMGGPYGGGNYGP-GGSGGSGGYGG 337
Score = 82.0 bits (201), Expect = 1e-15
Identities = 53/112 (47%), Positives = 63/112 (56%), Gaps = 13/112 (11%)
Query: 472 RGGGYG-GDRGGYGGDRGGGYGGDRGGYGGDRGGYGGDRGGYGGDRGGYGGDRSRGGYGG 530
RGG +G GD G GG+ G G G + + G GYG RG +G GYGG G GG
Sbjct: 191 RGGNFGFGDSRGGGGNFGPGPGSN---FRGGSDGYGSGRG-FGDGYNGYGG----GPGGG 242
Query: 531 DRGGGSGYGGDRSGGYGGDRSGGGYGGDRGGGYGGDRGGYGGKMGGRNDYRN 582
+ GG GYGG R GGYGG G GYG ++GGGYGG YGG G +Y +
Sbjct: 243 NFGGSPGYGGGR-GGYGG--GGPGYG-NQGGGYGGGYDNYGGGNYGSGNYND 290
Score = 56.6 bits (135), Expect = 6e-08
Identities = 45/169 (26%), Positives = 60/169 (35%), Gaps = 18/169 (10%)
Query: 18 STYGNPGSQGYGQASQSYSGYGQTTDSSYGQNYSGYSSYGQSYSQSYGGYENQKQSSYSQ 77
S G G+ G+G + +G S++ GY S G+ + Y GY
Sbjct: 187 SRSGRGGNFGFGDSRGGGGNFGPGPGSNFRGGSDGYGS-GRGFGDGYNGYGGGPGGG--- 242
Query: 78 QPYNNQGQQQNMESSGSQGGRAPSYDQPDYGQQDSYDQQSGYDQHQGSYDEQSNYDQQHD 137
N G G GG P Y G YD G + G+Y++ NY+QQ
Sbjct: 243 ---NFGGSPGYGGGRGGYGGGGPGYGNQGGGYGGGYDNYGGGNYGSGNYNDFGNYNQQPS 299
Query: 138 SYSQNQQSYHSQRENYSHHTQDDRRDVSRYGEDNRGYGGSQGGGRGRGG 186
+Y + N YG N G GGS GG G GG
Sbjct: 300 NYGPMKSGNFGGSRNMG----------GPYGGGNYGPGGS-GGSGGYGG 337
Score = 45.4 bits (106), Expect = 1e-04
Identities = 39/128 (30%), Positives = 47/128 (36%), Gaps = 17/128 (13%)
Query: 4 SGSYGQSGGEQQSYSTYGN-------PGSQGYGQASQSYSGYGQ---TTDSSYGQNYSGY 53
S YG G Y+ YG GS GYG Y G G YG Y Y
Sbjct: 219 SDGYGSGRGFGDGYNGYGGGPGGGNFGGSPGYGGGRGGYGGGGPGYGNQGGGYGGGYDNY 278
Query: 54 --SSYGQSYSQSYGGYENQKQSSYSQQPYNNQGQQQNMESSGSQGGRAPSYDQPDYGQQD 111
+YG +G Y NQ+ S+Y N G +NM G GG +Y G
Sbjct: 279 GGGNYGSGNYNDFGNY-NQQPSNYGPMKSGNFGGSRNM--GGPYGG--GNYGPGGSGGSG 333
Query: 112 SYDQQSGY 119
Y +S Y
Sbjct: 334 GYGGRSRY 341
Score = 42.0 bits (97), Expect = 0.002
Identities = 24/55 (43%), Positives = 29/55 (52%), Gaps = 12/55 (21%)
Query: 167 YGEDNRGYGGSQGGGR---------GRGGYDKDGRGPMTGSSGGD-RGGFKNFGG 211
+G+ GYGG GGG GRGGY G GP G+ GG GG+ N+GG
Sbjct: 228 FGDGYNGYGGGPGGGNFGGSPGYGGGRGGYG--GGGPGYGNQGGGYGGGYDNYGG 280
Score = 33.9 bits (76), Expect = 0.43
Identities = 65/266 (24%), Positives = 88/266 (33%), Gaps = 74/266 (27%)
Query: 106 DYGQQDSY----DQQSGYDQHQG--SYDEQSNYDQQHDSYSQNQQSYHS-QRENYSHHTQ 158
+YG+ D+ D+QSG + G ++D+ D+ Q YH+ N
Sbjct: 122 EYGKIDTIEIITDRQSGKKRGFGFVTFDDHDPVDKIV------LQKYHTINGHNAEVRKA 175
Query: 159 DDRRDVSRYGEDNRGYGGSQGGGRGRGGYDKDGRGPMTGSSGGDRG-------------- 204
R+++ G GG+ G G RGG G GP + GG G
Sbjct: 176 LSRQEMQEVQSSRSGRGGNFGFGDSRGGGGNFGPGPGSNFRGGSDGYGSGRGFGDGYNGY 235
Query: 205 ----GFKNFGGHRDYGPRTDADSESDNSDNNTIFVQGLGEGVSTDQVGEFFKQIGIIKTN 260
G NFGG YG N QG G G D G N
Sbjct: 236 GGGPGGGNFGGSPGYGGGRGGYGGGGPGYGN----QGGGYGGGYDNYG---------GGN 282
Query: 261 KKTGKPMINLYTDKDTGKPKGEATVSFDDPPSAKAAIDWFDGKEFHGNIIKVSFATRRPE 320
+G Y D +++ PS +G + +F R
Sbjct: 283 YGSGN-----YNDFG----------NYNQQPSN------------YGPMKSGNFGGSR-- 313
Query: 321 FMRGGGSGGGRRGRGGYRGRGGFQGR 346
GG GGG G GG G GG+ GR
Sbjct: 314 -NMGGPYGGGNYGPGGSGGSGGYGGR 338
>gi|56699482 hypothetical protein LOC25940 [Homo sapiens]
Length = 518
Score = 112 bits (281), Expect = 7e-25
Identities = 80/183 (43%), Positives = 89/183 (48%), Gaps = 22/183 (12%)
Query: 406 GGRGGDRGGYG----GDRSGGGYGGDRSSGGGYSGDRSGGGYGGDRSGGGYGGDRGGGYG 461
GGRGG RGGY G R G GG R GGY GGG G GG G GGG G
Sbjct: 334 GGRGGGRGGYEHSSYGGRGGHEQGGGRGGRGGYDHGGRGGGRGNKHQGGWTDGGSGGG-G 392
Query: 462 GDRGGGY--GGDRGGGYGGDRGGYGGDRGGGYGG-----DRGGYGGDRGGYGGDR----G 510
G + GGY G + GGY G GG +GGGYGG G G GGY D G
Sbjct: 393 GYQDGGYRDSGFQPGGYHGGHSS-GGYQGGGYGGFQTSSSYTGSGYQGGGYQQDNRYQDG 451
Query: 511 GYGGDR-GGYGGDRSRGGYGGDRGGGSGYGGDRSGGYGGDRSGGGYGGD-RGGGYGGDRG 568
G+ GDR GG GG RGG GG G G G+GG S Y GG + + GGY +
Sbjct: 452 GHHGDRGGGRGGRGGRGGRGGRAGQGGGWGGRGSQNY---HQGGQFEQHFQHGGYQYNHS 508
Query: 569 GYG 571
G+G
Sbjct: 509 GFG 511
Score = 105 bits (261), Expect = 2e-22
Identities = 90/223 (40%), Positives = 103/223 (46%), Gaps = 59/223 (26%)
Query: 374 NQCNEPRPE----------DSRPSGGDFRGRG------YGGERGYR---GRGGRGG-DRG 413
N+ P PE + +GG GRG YGG G+ GRGGRGG D G
Sbjct: 310 NEIEPPPPEMPPWQKRQDGPQQQTGGRGGGRGGYEHSSYGGRGGHEQGGGRGGRGGYDHG 369
Query: 414 GYGGDRS----GGGYGGDRSSGGGYS--GDRSGG----GYGGDRSGGGYGGDRGGGYGGD 463
G GG R GG G GGGY G R G GY G S GGY +GGGYGG
Sbjct: 370 GRGGGRGNKHQGGWTDGGSGGGGGYQDGGYRDSGFQPGGYHGGHSSGGY---QGGGYGGF 426
Query: 464 R------GGGYGGDRGGGYGGDR----GGYGGDRGGGYGGDRGGYGGDRGGYGGDRGGYG 513
+ G GY +GGGY D GG+ GDRGGG GG RGG GG RGG
Sbjct: 427 QTSSSYTGSGY---QGGGYQQDNRYQDGGHHGDRGGGRGG-RGGRGG--------RGGRA 474
Query: 514 GDRGGYGGDRSRGGYGGDRGGGSGYGGDRSGGYGGDRSGGGYG 556
G GG+GG S+ + GG + GGY + SG G G
Sbjct: 475 GQGGGWGGRGSQNYH----QGGQFEQHFQHGGYQYNHSGFGQG 513
Score = 101 bits (251), Expect = 2e-21
Identities = 76/166 (45%), Positives = 84/166 (50%), Gaps = 33/166 (19%)
Query: 388 GGDFRGRGYGGERGYRGRGGRGGDRGGY-------GGDRSGGGY--GGDRSSG---GGYS 435
GG +G G GG GY GGRGG RG GG GGGY GG R SG GGY
Sbjct: 352 GGHEQGGGRGGRGGY-DHGGRGGGRGNKHQGGWTDGGSGGGGGYQDGGYRDSGFQPGGYH 410
Query: 436 GDRS-----GGGYGGDRSGGGYGGD--RGGGYGGD---RGGGYGGDRGGGYGGDRGGYGG 485
G S GGGYGG ++ Y G +GGGY D + GG+ GDRGGG GG RGG GG
Sbjct: 411 GGHSSGGYQGGGYGGFQTSSSYTGSGYQGGGYQQDNRYQDGGHHGDRGGGRGG-RGGRGG 469
Query: 486 DRGG--GYGGDRGGYGGDRGGYGGD------RGGYGGDRGGYGGDR 523
RGG G GG GG G GG GGY + G+G R
Sbjct: 470 -RGGRAGQGGGWGGRGSQNYHQGGQFEQHFQHGGYQYNHSGFGQGR 514
Score = 93.2 bits (230), Expect = 6e-19
Identities = 69/147 (46%), Positives = 73/147 (49%), Gaps = 30/147 (20%)
Query: 454 GDRGGGYGGDRGGGYGGDRGGGYGGDRGGYGGDRGGGYGGDRGGYGGDRGGY--GGDRGG 511
G RGGG GG YGG G GG RGG GG GG GG RG +GG+ GG GG
Sbjct: 334 GGRGGGRGGYEHSSYGGRGGHEQGGGRGGRGGYDHGGRGGGRGNK--HQGGWTDGGSGGG 391
Query: 512 YGGDRGGY-----------GGDRSRGGYGGDRGG--------GSGYGGDRSGGYGGDR-- 550
G GGY GG S G GG GG GSGY G GGY D
Sbjct: 392 GGYQDGGYRDSGFQPGGYHGGHSSGGYQGGGYGGFQTSSSYTGSGYQG---GGYQQDNRY 448
Query: 551 SGGGYGGDRGGGYGGDRGGYGGKMGGR 577
GG+ GDRGGG GG RGG GG+ GGR
Sbjct: 449 QDGGHHGDRGGGRGG-RGGRGGR-GGR 473
Score = 49.3 bits (116), Expect = 1e-05
Identities = 71/260 (27%), Positives = 86/260 (33%), Gaps = 76/260 (29%)
Query: 189 KDGRGPMTGSSGGDRGGFKNFGGHRDYGPRTDADSESDNSDNNTIFVQGLGEGVSTDQVG 248
+DG TG GG RGG++ H YG R + G G G
Sbjct: 326 QDGPQQQTGGRGGGRGGYE----HSSYGGRGGHEQGGGRGGRGGYDHGGRGGG------- 374
Query: 249 EFFKQIGIIKTNKKTGKPMINLYTDKDTGKPKGEATVSFDDPPSAKAAIDWFDGKEFHGN 308
+ NK G +TD +G G + D
Sbjct: 375 ---------RGNKHQGG-----WTDGGSGGGGGYQDGGYRD------------------- 401
Query: 309 IIKVSFATRRPEFMRGGGSGGGRRGRGGYRGRGGFQGRGGDPKSGDWVCPNPSCGNMNFA 368
+ +P GG S GG +G GGY GGFQ SG
Sbjct: 402 ------SGFQPGGYHGGHSSGGYQG-GGY---GGFQTSSSYTGSG--------------Y 437
Query: 369 RRNSCNQCNEPRPEDSRPSGGDFRGRGYGGERGYRGRGGRGGDRGGYGGDRS----GGGY 424
+ Q N R +D G RG G GG G GRGGR G GG+GG S GG
Sbjct: 438 QGGGYQQDN--RYQDGGHHGD--RGGGRGGRGGRGGRGGRAGQGGGWGGRGSQNYHQGGQ 493
Query: 425 GGDRSSGGGYSGDRSGGGYG 444
GGY + SG G G
Sbjct: 494 FEQHFQHGGYQYNHSGFGQG 513
Score = 48.1 bits (113), Expect = 2e-05
Identities = 33/74 (44%), Positives = 35/74 (47%), Gaps = 10/74 (13%)
Query: 510 GGYGGDRGGYGGDRSRGGYGGDRGGGSGYGGDRS--GGYGGDRSGGGYGGDRGGGY--GG 565
GG GG RGGY YGG GG GG R GGY GGG G GG+ GG
Sbjct: 334 GGRGGGRGGY----EHSSYGGR--GGHEQGGGRGGRGGYDHGGRGGGRGNKHQGGWTDGG 387
Query: 566 DRGGYGGKMGGRND 579
GG G + GG D
Sbjct: 388 SGGGGGYQDGGYRD 401
Score = 44.7 bits (104), Expect = 2e-04
Identities = 59/207 (28%), Positives = 76/207 (36%), Gaps = 50/207 (24%)
Query: 9 QSGGEQQSYSTYGNPGSQGYGQASQSYSGYGQTTDSSYGQNYSGYSSYGQSYSQSYGGYE 68
Q G +QQ+ G +G G+ +S YG G G Y + GG
Sbjct: 326 QDGPQQQT-------GGRGGGRGGYEHSSYGGRGGHEQGGGRGGRGGY--DHGGRGGGRG 376
Query: 69 NQKQSSYSQQPYNNQGQQQNMESSGSQGGRAPSYDQPDYGQQDSYDQQSGYDQHQGSYDE 128
N+ Q ++ SG GG D G +DS Q GY H G
Sbjct: 377 NKHQGGWTDG------------GSGGGGG------YQDGGYRDSGFQPGGY--HGG---- 412
Query: 129 QSNYDQQHDSYSQNQQSYHSQRENYSHHTQDDRRDVSRYGEDNR----GYGGSQGGGR-G 183
S+ Q Y Q S Y Y +DNR G+ G +GGGR G
Sbjct: 413 HSSGGYQGGGYGGFQTSSSYTGSGYQG---------GGYQQDNRYQDGGHHGDRGGGRGG 463
Query: 184 RGGYDKDGRGPMTGSSGGDRG-GFKNF 209
RGG + GRG G GG G G +N+
Sbjct: 464 RGG--RGGRGGRAGQGGGWGGRGSQNY 488
Score = 43.5 bits (101), Expect = 5e-04
Identities = 41/154 (26%), Positives = 54/154 (35%), Gaps = 28/154 (18%)
Query: 2 SDSGSYGQSGGEQQSYSTYG-NPGSQGYGQASQSYSGYG----QTTDSSYGQNYSGYSSY 56
+D GS G G + Y G PG G +S Y G G QT+ S G Y G
Sbjct: 384 TDGGSGGGGGYQDGGYRDSGFQPGGYHGGHSSGGYQGGGYGGFQTSSSYTGSGYQG---- 439
Query: 57 GQSYSQSYGGYENQKQSSYSQQPYNNQGQQQNMESSGSQGGRAPSYDQPDYGQQDSYDQQ 116
GGY+ + + G + G +GGRA GQ + +
Sbjct: 440 --------GGYQQDNRYQDGGHHGDRGGGRGGRGGRGGRGGRA--------GQGGGWGGR 483
Query: 117 SGYDQHQGSYDEQSNYDQQHDSYSQNQQSYHSQR 150
+ HQG EQ QH Y N + R
Sbjct: 484 GSQNYHQGGQFEQ---HFQHGGYQYNHSGFGQGR 514
Score = 43.1 bits (100), Expect = 7e-04
Identities = 44/173 (25%), Positives = 62/173 (35%), Gaps = 35/173 (20%)
Query: 65 GGYENQKQSSYSQQPYNNQGQQQNMESSGSQGGRAPSYDQPDYGQQDSYDQ------QSG 118
GG N+ + + P + Q + +G +GG Y+ YG + ++Q + G
Sbjct: 306 GGRPNEIEPPPPEMPPWQKRQDGPQQQTGGRGGGRGGYEHSSYGGRGGHEQGGGRGGRGG 365
Query: 119 YD----------QHQGSY-DEQSNYDQQHDSYSQNQQSYHSQRENYSHHTQDDRRDVSRY 167
YD +HQG + D S + + + H S
Sbjct: 366 YDHGGRGGGRGNKHQGGWTDGGSGGGGGYQDGGYRDSGFQPGGYHGGH---------SSG 416
Query: 168 GEDNRGYGGSQ------GGGRGRGGYDKDGR---GPMTGSSGGDRGGFKNFGG 211
G GYGG Q G G GGY +D R G G GG RGG GG
Sbjct: 417 GYQGGGYGGFQTSSSYTGSGYQGGGYQQDNRYQDGGHHGDRGGGRGGRGGRGG 469
Score = 38.1 bits (87), Expect = 0.023
Identities = 29/89 (32%), Positives = 39/89 (43%), Gaps = 3/89 (3%)
Query: 128 EQSNYDQQHDSYSQNQQSYHSQRENYSHHTQDDRRDVSRYGEDNRGYGGSQGGGRGRGGY 187
E + ++ D Q R Y H + R + G G GG GGRG G
Sbjct: 318 EMPPWQKRQDGPQQQTGGRGGGRGGYEHSSYGGRGGHEQ-GGGRGGRGGYDHGGRGGGRG 376
Query: 188 DKDGRGPMTGSSGGDRGGFKNFGGHRDYG 216
+K G G SGG GG+++ GG+RD G
Sbjct: 377 NKHQGGWTDGGSGGG-GGYQD-GGYRDSG 403
Score = 32.3 bits (72), Expect = 1.3
Identities = 21/45 (46%), Positives = 24/45 (53%), Gaps = 7/45 (15%)
Query: 547 GGDRSGGGYGGDRGG----GYGGDRGGY--GGKMGGRNDYRNDQR 585
G + GG GG RGG YGG RGG+ GG GGR Y + R
Sbjct: 328 GPQQQTGGRGGGRGGYEHSSYGG-RGGHEQGGGRGGRGGYDHGGR 371
>gi|109148552 keratin 3 [Homo sapiens]
Length = 628
Score = 107 bits (268), Expect = 2e-23
Identities = 73/167 (43%), Positives = 85/167 (50%), Gaps = 18/167 (10%)
Query: 409 GGDRGGYGGDRSGGGYGGDRSSGGGYSGDRSGGGYGGDRSGGGYGGDRGGGYGGDRGGGY 468
GG G+ G RS G R S +SG GG YG GG+G GG++
Sbjct: 10 GGGSQGFSG-RSAVVSGSSRMSCVAHSGGAGGGAYGFRSGAGGFGSRSLYNLGGNKSISI 68
Query: 469 ----GGDRGGGYGGDR------GGYGGDRGGGYGGDRGGYGGDRGGYGGDRGGYGGDRGG 518
GG R GG+GG R GGYGG G GYGG G+GG GG G GG+GG GG
Sbjct: 69 SVAAGGSRAGGFGGGRSSCAFAGGYGGGFGSGYGG---GFGGGFGGGRGMGGGFGG-AGG 124
Query: 519 YGGDRSRGGYGGDRGGGSGYGGDRSGGYGGDRSGGGYGGDRGGGYGG 565
+GG GG GG GG G+GG SGG+GG S G GG GG+ G
Sbjct: 125 FGGAGGFGGAGG-FGGPGGFGG--SGGFGGPGSLGSPGGFGPGGFPG 168
Score = 83.6 bits (205), Expect = 5e-16
Identities = 70/160 (43%), Positives = 82/160 (51%), Gaps = 33/160 (20%)
Query: 384 SRPSGGDFRGRGYGGERGYRGRGGRGGDRGGY--GGDRS-----------GGGYGGDRSS 430
SR S G GG G+R G G R Y GG++S GG+GG RSS
Sbjct: 27 SRMSCVAHSGGAGGGAYGFRSGAGGFGSRSLYNLGGNKSISISVAAGGSRAGGFGGGRSS 86
Query: 431 ---GGGYSGDRSGGGYGGDRSGGGYGGDRGGGYGGDRGGGYGGDRGGGYGGDRGGYGGDR 487
GGY G G GYGG GGG+GG RG GG G+GG GG+GG GG+GG
Sbjct: 87 CAFAGGYGGG-FGSGYGGG-FGGGFGGGRG--MGG----GFGG--AGGFGG-AGGFGG-- 133
Query: 488 GGGYGGDRGGYGGDRGGYGGDRGGYGGDRGGYGGDRSRGG 527
GG+GG GG+GG GG+GG G G GG+G GG
Sbjct: 134 AGGFGGP-GGFGGS-GGFGGP--GSLGSPGGFGPGGFPGG 169
Score = 82.0 bits (201), Expect = 1e-15
Identities = 66/149 (44%), Positives = 75/149 (50%), Gaps = 21/149 (14%)
Query: 439 SGGGYGG--DRSGGGYGGDRGGGY---GGDRGGGYGGDRGGGYGGDRGGY--GGDRGGGY 491
SGGG G RS G R GG GG YG G G G R Y GG++
Sbjct: 9 SGGGSQGFSGRSAVVSGSSRMSCVAHSGGAGGGAYGFRSGAGGFGSRSLYNLGGNKSISI 68
Query: 492 GGDRGGYGGDRGGYGGDR------GGYGGDRG-GYGGDRSRGGYGGDRGGGSGYGGDRSG 544
GG GG+GG R GGYGG G GYGG GG+GG RG G G+GG +G
Sbjct: 69 SVAAGG--SRAGGFGGGRSSCAFAGGYGGGFGSGYGGGFG-GGFGGGRGMGGGFGG--AG 123
Query: 545 GYGGDRSGGGYGGDRG-GGYGGDRGGYGG 572
G+GG GG GG G GG+GG GG+GG
Sbjct: 124 GFGGAGGFGGAGGFGGPGGFGGS-GGFGG 151
Score = 79.0 bits (193), Expect = 1e-14
Identities = 72/195 (36%), Positives = 87/195 (44%), Gaps = 43/195 (22%)
Query: 305 FHGNIIKVSFATRRPEFMRGGGSGGGRRGRGGYRGRGGFQGRGGDPKSGDWVCPNPSCGN 364
F G VS ++R GG+GGG G G GGF R S N
Sbjct: 16 FSGRSAVVSGSSRMSCVAHSGGAGGGAYGFRS--GAGGFGSR--------------SLYN 59
Query: 365 MNFARRNSCNQCNEPRPEDSRPSGGDFRGRGYGGERGYRG-RGGRGGDRG-GYGGDRSGG 422
+ + S + + G R G+GG R GG GG G GYGG GG
Sbjct: 60 LGGNKSISISV-----------AAGGSRAGGFGGGRSSCAFAGGYGGGFGSGYGGG-FGG 107
Query: 423 GYGGDRSSGGGYSGDRSGGGYGGDRSGGGYGGDRGGGYGGDRGGGYGGDRGGGYGGDRGG 482
G+GG R GGG+ G GG+GG GG+GG GG+GG GG+GG GG+GG G
Sbjct: 108 GFGGGRGMGGGFGG---AGGFGG---AGGFGG--AGGFGGP--GGFGG--SGGFGGP-GS 154
Query: 483 YGGDRGGGYGGDRGG 497
G G G GG GG
Sbjct: 155 LGSPGGFGPGGFPGG 169
Score = 74.7 bits (182), Expect = 2e-13
Identities = 62/145 (42%), Positives = 70/145 (48%), Gaps = 34/145 (23%)
Query: 448 SGGGYGGDRGGGYGGDRGGGYGGDR------GGGYGGDRGGYGGDRGGGYGGDRGGYGGD 501
SGGG G+ G G R GG GG G YG G G G R Y
Sbjct: 9 SGGG-----SQGFSGRSAVVSGSSRMSCVAHSGGAGG--GAYGFRSGAGGFGSRSLYN-- 59
Query: 502 RGGYGGDRG-----GYGGDR-GGYGGDRSR----GGYGGDRGGGSGYGGDRSGGYGGDRS 551
GG++ GG R GG+GG RS GGYGG G GSGYGG GG+GG R
Sbjct: 60 ---LGGNKSISISVAAGGSRAGGFGGGRSSCAFAGGYGG--GFGSGYGGGFGGGFGGGRG 114
Query: 552 -GGGYGGDRGGGYGGDRGGYGGKMG 575
GGG+GG GG+GG GG+GG G
Sbjct: 115 MGGGFGG--AGGFGG-AGGFGGAGG 136
Score = 72.8 bits (177), Expect = 8e-13
Identities = 39/81 (48%), Positives = 45/81 (55%), Gaps = 3/81 (3%)
Query: 448 SGGGYGGDRGGGYGGDRGGGYGGDRGGGYGGDRGGYGGDRGGGYGGDRGGYGGDRGGYGG 507
S GGYGG GGG GG GGG+ G G G RGG GG GGG+GG G+ G G+G
Sbjct: 534 SAGGYGGGYGGGMGGGLGGGFSAGGGSGSGFGRGG-GGGIGGGFGGGSSGFSGG-SGFGS 591
Query: 508 DRGG-YGGDRGGYGGDRSRGG 527
G YG GG+ +RGG
Sbjct: 592 ISGARYGVSGGGFSSASNRGG 612
Score = 66.2 bits (160), Expect = 8e-11
Identities = 38/91 (41%), Positives = 43/91 (47%), Gaps = 14/91 (15%)
Query: 458 GGYGGDRGGGYGGDRGGGYGGDRGGYGGDRGGGYGGDRGGYGGDRGGYGGDRGGYGGDRG 517
GGYGG GGG GG GGG+ GG G G+G RGG GG GG+GG
Sbjct: 536 GGYGGGYGGGMGGGLGGGFSA-----GGGSGSGFG---------RGGGGGIGGGFGGGSS 581
Query: 518 GYGGDRSRGGYGGDRGGGSGYGGDRSGGYGG 548
G+ G G G R G SG G + GG
Sbjct: 582 GFSGGSGFGSISGARYGVSGGGFSSASNRGG 612
Score = 65.1 bits (157), Expect = 2e-10
Identities = 40/88 (45%), Positives = 45/88 (51%), Gaps = 11/88 (12%)
Query: 474 GGYGGDRGGYGGDRGGGYGGDRGGYGGDRGGYGGDRGGYGGDRGGYGGDRSRGGYGGDRG 533
GGYGG GYGG GGG GG GG G+G RGG GG GG+GG S G+
Sbjct: 536 GGYGG---GYGGGMGGGLGGGFSAGGGSGSGFG--RGGGGGIGGGFGGGSS--GF----S 584
Query: 534 GGSGYGGDRSGGYGGDRSGGGYGGDRGG 561
GGSG+G YG G +RGG
Sbjct: 585 GGSGFGSISGARYGVSGGGFSSASNRGG 612
Score = 64.7 bits (156), Expect = 2e-10
Identities = 39/87 (44%), Positives = 44/87 (50%), Gaps = 10/87 (11%)
Query: 420 SGGGYGGDRSSGGGYSGDRSGGGYGGDRSGGGYGGDRGGGYGGDRGGGYGGDRGGGYGGD 479
S GGYGG GY G GG GG +GGG G G G GG GGG+GG G GG
Sbjct: 534 SAGGYGG------GYGGGMGGGLGGGFSAGGGSGSGFGRGGGGGIGGGFGGGSSGFSGG- 586
Query: 480 RGGYGGDRGGGYGGDRGGY--GGDRGG 504
G+G G YG GG+ +RGG
Sbjct: 587 -SGFGSISGARYGVSGGGFSSASNRGG 612
Score = 63.2 bits (152), Expect = 7e-10
Identities = 41/84 (48%), Positives = 46/84 (54%), Gaps = 10/84 (11%)
Query: 409 GGDRGGYGGDRSGGGYGGDRSSGGGYSGDRSGGGYGGDRSGGGYGGDRGGGYGGDRGG-G 467
GG GGYGG GGG GG S+GGG SG G+G GGG GG GGG G GG G
Sbjct: 536 GGYGGGYGGGM-GGGLGGGFSAGGG-----SGSGFGRG-GGGGIGGGFGGGSSGFSGGSG 588
Query: 468 YGGDRGGGYGGDRGGY--GGDRGG 489
+G G YG GG+ +RGG
Sbjct: 589 FGSISGARYGVSGGGFSSASNRGG 612
Score = 62.4 bits (150), Expect = 1e-09
Identities = 41/110 (37%), Positives = 50/110 (45%), Gaps = 11/110 (10%)
Query: 477 GGDRGGYGGDRGGGYGGDRGGYGGDRGGYGGDRGGYGGDRGGYGGDRSRGGYGGDRGGGS 536
GG G+ G G R GG GG G+ GG+G RS GG++
Sbjct: 10 GGGSQGFSGRSAVVSGSSRMSCVAHSGGAGGGAYGFRSGAGGFGS-RSLYNLGGNKSISI 68
Query: 537 GY--GGDRSGGYGGDRS--------GGGYGGDRGGGYGGDRGGYGGKMGG 576
GG R+GG+GG RS GGG+G GGG+GG GG G GG
Sbjct: 69 SVAAGGSRAGGFGGGRSSCAFAGGYGGGFGSGYGGGFGGGFGGGRGMGGG 118
Score = 60.1 bits (144), Expect = 6e-09
Identities = 36/78 (46%), Positives = 38/78 (48%), Gaps = 12/78 (15%)
Query: 496 GGYGGDRGGYGGDRGGYGGDRGGYGGDRSRGGYGGD---RGGGSGYGGDRSGGYGGDRSG 552
GGYGG GYGG G GG GG S GG G RGGG G GG GG G G
Sbjct: 536 GGYGG---GYGGGMG------GGLGGGFSAGGGSGSGFGRGGGGGIGGGFGGGSSGFSGG 586
Query: 553 GGYGGDRGGGYGGDRGGY 570
G+G G YG GG+
Sbjct: 587 SGFGSISGARYGVSGGGF 604
Score = 56.2 bits (134), Expect = 8e-08
Identities = 29/67 (43%), Positives = 32/67 (47%)
Query: 510 GGYGGDRGGYGGDRSRGGYGGDRGGGSGYGGDRSGGYGGDRSGGGYGGDRGGGYGGDRGG 569
GGYGG GG G GG+ G GSG+G GG GG GG G G G+G G
Sbjct: 536 GGYGGGYGGGMGGGLGGGFSAGGGSGSGFGRGGGGGIGGGFGGGSSGFSGGSGFGSISGA 595
Query: 570 YGGKMGG 576
G GG
Sbjct: 596 RYGVSGG 602
Score = 54.3 bits (129), Expect = 3e-07
Identities = 33/81 (40%), Positives = 35/81 (43%), Gaps = 5/81 (6%)
Query: 395 GYGGERGYRGRGGRGGDRGGYGGDRSGGGYGGDRSSGGGYSGDRSGGGYGGDRSGGGYGG 454
GYGG G GG GG GG SG G GG GGG+ GGG G G G+G
Sbjct: 537 GYGGGYGGGMGGGLGGGFSAGGGSGSGFGRGGGGGIGGGF-----GGGSSGFSGGSGFGS 591
Query: 455 DRGGGYGGDRGGGYGGDRGGG 475
G YG GG GG
Sbjct: 592 ISGARYGVSGGGFSSASNRGG 612
Score = 53.9 bits (128), Expect = 4e-07
Identities = 35/80 (43%), Positives = 38/80 (47%), Gaps = 6/80 (7%)
Query: 406 GGRGGDRGGYGGDRSGGGY--GGDRSSGGGYSGDRSGGGYGGDRSGGGYGGDRGGGYGGD 463
GG GG GG G GGG+ GG SG G G GGG GG GG G G G+G
Sbjct: 536 GGYGGGYGGGMGGGLGGGFSAGGGSGSGFGRGG---GGGIGGGFGGGSSGFSGGSGFGSI 592
Query: 464 RGGGYGGDRGG-GYGGDRGG 482
G YG GG +RGG
Sbjct: 593 SGARYGVSGGGFSSASNRGG 612
Score = 46.2 bits (108), Expect = 8e-05
Identities = 30/73 (41%), Positives = 33/73 (45%), Gaps = 2/73 (2%)
Query: 388 GGDFRGRGYGGERGYRGRGGRGGDRGGYGGDRSGGGYGGDRS--SGGGYSGDRSGGGYGG 445
GG G G G G+ GG G G GG GGG+GG S SGG G SG YG
Sbjct: 540 GGYGGGMGGGLGGGFSAGGGSGSGFGRGGGGGIGGGFGGGSSGFSGGSGFGSISGARYGV 599
Query: 446 DRSGGGYGGDRGG 458
G +RGG
Sbjct: 600 SGGGFSSASNRGG 612
Score = 45.4 bits (106), Expect = 1e-04
Identities = 33/77 (42%), Positives = 34/77 (44%), Gaps = 5/77 (6%)
Query: 393 GRGYGGERGYRGRGG--RGGDRGGYGGDRSGGGYGGDRSSGGGYSGDRSGGGYGGDRSGG 450
G GYGG G GG GG G G GGG GG GGG SG G G+ G SG
Sbjct: 539 GGGYGGGMGGGLGGGFSAGGGSGSGFGRGGGGGIGG--GFGGGSSGFSGGSGF-GSISGA 595
Query: 451 GYGGDRGGGYGGDRGGG 467
YG GG GG
Sbjct: 596 RYGVSGGGFSSASNRGG 612
Score = 36.6 bits (83), Expect = 0.066
Identities = 21/47 (44%), Positives = 22/47 (46%), Gaps = 6/47 (12%)
Query: 536 SGYGGDRSGGYGGDRSGG-----GYGGDRGGGYG-GDRGGYGGKMGG 576
S G GGYGG GG GG G G+G G GG GG GG
Sbjct: 532 SASAGGYGGGYGGGMGGGLGGGFSAGGGSGSGFGRGGGGGIGGGFGG 578
Score = 34.7 bits (78), Expect = 0.25
Identities = 21/51 (41%), Positives = 23/51 (45%), Gaps = 8/51 (15%)
Query: 173 GYGGSQGGGRGRGGYDKD-------GRGPMTGSSGGDRGGFKNFGGHRDYG 216
GYGG GGG G GG+ GRG G GG GG F G +G
Sbjct: 541 GYGGGMGGGLG-GGFSAGGGSGSGFGRGGGGGIGGGFGGGSSGFSGGSGFG 590
Score = 34.7 bits (78), Expect = 0.25
Identities = 24/81 (29%), Positives = 36/81 (44%), Gaps = 9/81 (11%)
Query: 5 GSYGQSGGEQQSYSTYGNPG-SQGYGQASQSYSG---YGQTTDSSYGQNYSGYSSYGQSY 60
G + GG + G G G+G S +SG +G + + YG + G+SS
Sbjct: 552 GGFSAGGGSGSGFGRGGGGGIGGGFGGGSSGFSGGSGFGSISGARYGVSGGGFSS----- 606
Query: 61 SQSYGGYENQKQSSYSQQPYN 81
+ + GG QSS S Q Y+
Sbjct: 607 ASNRGGSIKFSQSSQSSQRYS 627
Score = 33.1 bits (74), Expect = 0.73
Identities = 19/37 (51%), Positives = 20/37 (54%), Gaps = 7/37 (18%)
Query: 543 SGGYGGDRSGGGYGGDRGGGYGG--DRGGYGGKMGGR 577
+GGYGG GYGG GGG GG GG G GR
Sbjct: 535 AGGYGG-----GYGGGMGGGLGGGFSAGGGSGSGFGR 566
Score = 31.6 bits (70), Expect = 2.1
Identities = 19/39 (48%), Positives = 20/39 (51%), Gaps = 6/39 (15%)
Query: 173 GYGGSQGGGRGRGGYDKDGRGPMTGSSGGDRGGFKNFGG 211
G+GG GGGRG GG G G G G GGF GG
Sbjct: 104 GFGGGFGGGRGMGG----GFGGAGGFGGA--GGFGGAGG 136
Score = 31.6 bits (70), Expect = 2.1
Identities = 34/116 (29%), Positives = 38/116 (32%), Gaps = 35/116 (30%)
Query: 324 GGGSGGGRRGRGGYRGRGGFQGRGGDPKSGDWVCPNPSCGNMNFARRNSCNQCNEPRPED 383
GGG GGG G G GGF GG SG
Sbjct: 539 GGGYGGGMGGGLG----GGFSAGGG---SGSGF--------------------------- 564
Query: 384 SRPSGGDFRGRGYGGERGYRGRGGRGGDRGGYGGDRSGGGYGGDRSSGGGYSGDRS 439
R GG G GG G+ G G G G G SGGG+ + GG +S
Sbjct: 565 GRGGGGGIGGGFGGGSSGFSGGSGFGSISGARYG-VSGGGFSSASNRGGSIKFSQS 619
Score = 30.4 bits (67), Expect = 4.8
Identities = 17/39 (43%), Positives = 17/39 (43%)
Query: 173 GYGGSQGGGRGRGGYDKDGRGPMTGSSGGDRGGFKNFGG 211
GYGG G G G G G G G G GGF GG
Sbjct: 92 GYGGGFGSGYGGGFGGGFGGGRGMGGGFGGAGGFGGAGG 130
Score = 30.0 bits (66), Expect = 6.2
Identities = 18/44 (40%), Positives = 22/44 (50%), Gaps = 1/44 (2%)
Query: 173 GYGGSQGGGRGRGGYDKDGRGPMTGSSGGDRGGFKNFGGHRDYG 216
G+GG +G G G GG G G +GG GG FGG +G
Sbjct: 108 GFGGGRGMGGGFGGAGGFGGAGGFGGAGG-FGGPGGFGGSGGFG 150
Score = 29.6 bits (65), Expect = 8.1
Identities = 18/33 (54%), Positives = 18/33 (54%), Gaps = 1/33 (3%)
Query: 321 FMRGGGSGGGRRGRGGYRGRGGFQGRGGDPKSG 353
F GGGSG G GRGG G GG G G SG
Sbjct: 554 FSAGGGSGSG-FGRGGGGGIGGGFGGGSSGFSG 585
>gi|5803036 heterogeneous nuclear ribonucleoprotein A0 [Homo
sapiens]
Length = 305
Score = 102 bits (253), Expect = 1e-21
Identities = 61/125 (48%), Positives = 67/125 (53%), Gaps = 7/125 (5%)
Query: 420 SGGGYGGDRSSGGGYSGDRSGGG--YGGDRSGGGYGGDRGGGYGGDRGGGYGGDRGGGYG 477
SGGG GG RSS GG G GGG G GGG G + GGYGG GGGY GGG G
Sbjct: 181 SGGGGGGSRSSRGGRGGRGRGGGRDQNGLSKGGGGGYNSYGGYGGGGGGGYNAYGGGGGG 240
Query: 478 GDRGGYGGDRGGGYGGDRGGYGGDRGGYGGDRGGYGGDRGG--YGGDRSRGGYGGDRGGG 535
G G D G G+GG G Y + YG + G GG GG +GG + G Y G GGG
Sbjct: 241 SSYG--GSDYGNGFGG-FGSYSQHQSSYGPMKSGGGGGGGGSSWGGRSNSGPYRGGYGGG 297
Query: 536 SGYGG 540
GYGG
Sbjct: 298 GGYGG 302
Score = 96.3 bits (238), Expect = 7e-20
Identities = 86/266 (32%), Positives = 111/266 (41%), Gaps = 53/266 (19%)
Query: 218 RTDADSESDNSDNNTIFVQGLGEGVSTDQVGEFFKQIGIIKTNKKTGKPMINLYTDKDTG 277
R D+ ++ +FV GL V+ + E F Q G ++ + + DK +G
Sbjct: 85 REDSARPGAHAKVKKLFVGGLKGDVAEGDLIEHFSQFGTVEKAE--------IIADKQSG 136
Query: 278 KPKGEATVSFDDPPSA-KAAIDWFDGKEFHGNIIKVSFATRRPEFMRGGGSGGGRRGRGG 336
K +G V F + +A KAA+ F G+ ++V A + + GGG GG R RGG
Sbjct: 137 KKRGFGFVYFQNHDAADKAAVVKFH--PIQGHRVEVKKAVPKEDIYSGGGGGGSRSSRGG 194
Query: 337 Y--RGRGGFQGRGGDPKSGDWVCPNPSCGNMNFARRNSCNQCNEPRPEDSRPSGGDFRGR 394
RGRGG + + G K G G N + G
Sbjct: 195 RGGRGRGGGRDQNGLSKGGG--------GGYN-----------------------SYGGY 223
Query: 395 GYGGERGYRGRGGRGGDRGGYGGDRSGGGYGGDRSSGGGYSGDRSGGGYGGDRSGGGYGG 454
G GG GY GG GG YGG G G+GG G YS +S G GGG GG
Sbjct: 224 GGGGGGGYNAYGGGGGG-SSYGGSDYGNGFGGF----GSYSQHQSSYGPMKSGGGGGGGG 278
Query: 455 DRGGG--YGGDRGGGYGGDRGGGYGG 478
GG G GGYGG GGGYGG
Sbjct: 279 SSWGGRSNSGPYRGGYGG--GGGYGG 302
Score = 95.5 bits (236), Expect = 1e-19
Identities = 66/140 (47%), Positives = 73/140 (52%), Gaps = 16/140 (11%)
Query: 386 PSGGDFRGRGYGGERGYRGRGGRGGDRGGYGGDRSGGGYGGDRSSGGGYSGDRSGGGYGG 445
P + G G GG R RGGRGG G G D++G GG GGGY+ S GGYGG
Sbjct: 175 PKEDIYSGGGGGGSRS--SRGGRGGRGRGGGRDQNGLSKGG----GGGYN---SYGGYGG 225
Query: 446 DRSGG--GYGGDRGGG-YGG-DRGGGYGGDRGGGYGGDRGGYGGDRGGGYGGDRGGYGGD 501
GG YGG GG YGG D G G+GG G Y + YG + GG GG G G
Sbjct: 226 GGGGGYNAYGGGGGGSSYGGSDYGNGFGGF--GSYSQHQSSYGPMKSGGGGGGGGSSWGG 283
Query: 502 RGGYGGDRGGYGGDRGGYGG 521
R G RGGYGG GGYGG
Sbjct: 284 RSNSGPYRGGYGGG-GGYGG 302
Score = 95.1 bits (235), Expect = 2e-19
Identities = 66/132 (50%), Positives = 71/132 (53%), Gaps = 15/132 (11%)
Query: 439 SGGGYGGDRSGGGYGGDRGGGYGGDRGG-GYGGDRGGGYGGDRGGYGGDRGGGYGGDRGG 497
SGGG GG RS G G RG G G D+ G GG GGGY GGYGG GGGY GG
Sbjct: 181 SGGGGGGSRSSRGGRGGRGRGGGRDQNGLSKGG--GGGY-NSYGGYGGGGGGGYNAYGGG 237
Query: 498 YGGDRGGYGGDRGGYGGDRGGYGG-DRSRGGYGGDRGGGSGYGGDRSGGYGGDRSG---G 553
GG YGG YG GG+G + + YG + GG G GG S G G SG G
Sbjct: 238 GGG--SSYGG--SDYGNGFGGFGSYSQHQSSYGPMKSGGGGGGGGSSWG-GRSNSGPYRG 292
Query: 554 GYGGDRGGGYGG 565
GYGG GGGYGG
Sbjct: 293 GYGG--GGGYGG 302
Score = 77.4 bits (189), Expect = 3e-14
Identities = 53/123 (43%), Positives = 58/123 (47%), Gaps = 18/123 (14%)
Query: 468 YGGDRGGGYGGDRGGYGGDRGGGYGGDRGGY----GGDRGGYGGDRGGYGGDRGGYGGDR 523
Y G GGG RGG GG RG G G D+ G GG YGG GG GG YGG
Sbjct: 180 YSGGGGGGSRSSRGGRGG-RGRGGGRDQNGLSKGGGGGYNSYGGYGGGGGGGYNAYGGGG 238
Query: 524 SRGGYGGDRGGGSGYGG-----DRSGGYGGDRSGGGYGGDRGGGYGGD------RGGYGG 572
YGG G+G+GG YG +SGGG GG G +GG RGGYGG
Sbjct: 239 GGSSYGGS-DYGNGFGGFGSYSQHQSSYGPMKSGGG-GGGGGSSWGGRSNSGPYRGGYGG 296
Query: 573 KMG 575
G
Sbjct: 297 GGG 299
Score = 73.2 bits (178), Expect = 6e-13
Identities = 49/111 (44%), Positives = 54/111 (48%), Gaps = 18/111 (16%)
Query: 483 YGGDRGGGYGGDRGGYGGDRGGYGGDRGGYGGDRGGYGGDRSRGGYGGDRGGG-SGYGGD 541
Y G GGG RGG GG G GG R G +GG GG S GGYGG GGG + YGG
Sbjct: 180 YSGGGGGGSRSSRGGRGGR--GRGGGRDQNGLSKGGGGGYNSYGGYGGGGGGGYNAYGGG 237
Query: 542 RSG-GYGGDRSGGGYGGDRGGGY------------GGDRGGYGGKMGGRND 579
G YGG G G+GG G Y GG GG G GGR++
Sbjct: 238 GGGSSYGGSDYGNGFGG--FGSYSQHQSSYGPMKSGGGGGGGGSSWGGRSN 286
Score = 65.9 bits (159), Expect = 1e-10
Identities = 38/68 (55%), Positives = 39/68 (57%), Gaps = 2/68 (2%)
Query: 517 GGYGGDRS-RGGYGG-DRGGGSGYGGDRSGGYGGDRSGGGYGGDRGGGYGGDRGGYGGKM 574
GG GG RS RGG GG RGGG G GG GG S GGYGG GGGY GG GG
Sbjct: 183 GGGGGSRSSRGGRGGRGRGGGRDQNGLSKGGGGGYNSYGGYGGGGGGGYNAYGGGGGGSS 242
Query: 575 GGRNDYRN 582
G +DY N
Sbjct: 243 YGGSDYGN 250
Score = 42.4 bits (98), Expect = 0.001
Identities = 37/118 (31%), Positives = 49/118 (41%), Gaps = 22/118 (18%)
Query: 5 GSYGQSGGEQQSYSTYGNPGSQGYGQASQSYSGYGQTTD---SSYGQNYSGYSSYGQSYS 61
G G+ GG Q N S+G G SY GYG ++YG G S G Y
Sbjct: 196 GGRGRGGGRDQ------NGLSKGGGGGYNSYGGYGGGGGGGYNAYGGGGGGSSYGGSDYG 249
Query: 62 QSYGGYENQKQSSYSQQPYNNQGQQQNMESSGSQGGRAPSYDQPDYGQQDSYDQQSGY 119
+GG+ SYSQ +Q M+S G GG S+ G+ +S + GY
Sbjct: 250 NGFGGF-----GSYSQ----HQSSYGPMKSGGGGGGGGSSWG----GRSNSGPYRGGY 294
Score = 37.0 bits (84), Expect = 0.051
Identities = 24/79 (30%), Positives = 32/79 (40%), Gaps = 5/79 (6%)
Query: 139 YSQNQQSYHSQRENYSHHTQDDRRDVSRYGEDNRGYGGSQGGGR-----GRGGYDKDGRG 193
Y QN + H Q R +V + Y G GGG GRGG + G
Sbjct: 145 YFQNHDAADKAAVVKFHPIQGHRVEVKKAVPKEDIYSGGGGGGSRSSRGGRGGRGRGGGR 204
Query: 194 PMTGSSGGDRGGFKNFGGH 212
G S G GG+ ++GG+
Sbjct: 205 DQNGLSKGGGGGYNSYGGY 223
Score = 33.5 bits (75), Expect = 0.56
Identities = 29/102 (28%), Positives = 37/102 (36%), Gaps = 17/102 (16%)
Query: 25 SQGYGQASQSYSGYGQTTDSSYGQNYSGYSSYGQSYSQSYGGYENQKQSSYSQQPYNNQG 84
S G G S+S G G++ +G S G SYGGY Y
Sbjct: 181 SGGGGGGSRSSRGGRGGRGRGGGRDQNGLSKGGGGGYNSYGGYGGGGGGGY--------- 231
Query: 85 QQQNMESSGSQGGRAPSYDQPDYGQQDSYDQQSGYDQHQGSY 126
++ GG SY DYG + + Y QHQ SY
Sbjct: 232 ------NAYGGGGGGSSYGGSDYG--NGFGGFGSYSQHQSSY 265
Score = 33.5 bits (75), Expect = 0.56
Identities = 26/62 (41%), Positives = 29/62 (46%), Gaps = 13/62 (20%)
Query: 165 SRYGEDNRGYGG-------SQGGGRG---RGGYDKDGRGPMTGSSGGDRGGFKNFGGHRD 214
SR G RG GG S+GGG G GGY G G GG GG ++GG D
Sbjct: 191 SRGGRGGRGRGGGRDQNGLSKGGGGGYNSYGGYGGGGGGGYNAYGGG--GGGSSYGG-SD 247
Query: 215 YG 216
YG
Sbjct: 248 YG 249
Score = 31.2 bits (69), Expect = 2.8
Identities = 20/48 (41%), Positives = 23/48 (47%), Gaps = 5/48 (10%)
Query: 173 GYGGSQGGGRGRGGYDKDGRGPMTGSS--GGDRGGFKNFGGHR-DYGP 217
GYGG GG G Y G G G S G GGF ++ H+ YGP
Sbjct: 222 GYGGGGGG--GYNAYGGGGGGSSYGGSDYGNGFGGFGSYSQHQSSYGP 267
Score = 31.2 bits (69), Expect = 2.8
Identities = 22/63 (34%), Positives = 27/63 (42%), Gaps = 14/63 (22%)
Query: 168 GEDNRGYGGSQGG--------GRGRGGYD-----KDGRGPMTGSSGGDRGGFKNFGGHRD 214
G YGG GG G G GG+ + GPM S GG GG ++GG +
Sbjct: 228 GGGYNAYGGGGGGSSYGGSDYGNGFGGFGSYSQHQSSYGPMK-SGGGGGGGGSSWGGRSN 286
Query: 215 YGP 217
GP
Sbjct: 287 SGP 289
>gi|4504445 heterogeneous nuclear ribonucleoprotein A1 isoform a
[Homo sapiens]
Length = 320
Score = 100 bits (248), Expect = 5e-21
Identities = 81/291 (27%), Positives = 114/291 (39%), Gaps = 70/291 (24%)
Query: 218 RTDADSESDNSDNNTIFVQGLGEGVSTDQVGEFFKQIGIIKTNKKTGKPMINLYTDKDTG 277
R D+ + IFV G+ E + ++F+Q G I+ +I + TD+ +G
Sbjct: 92 REDSQRPGAHLTVKKIFVGGIKEDTEEHHLRDYFEQYGKIE--------VIEIMTDRGSG 143
Query: 278 KPKGEATVSFDDPPSAKAAIDWFDGKEFH---GNIIKVSFATRRPEFMRGGGSGGGRRGR 334
K +G A V+FDD S +D +++H G+ +V A + E S GR G
Sbjct: 144 KKRGFAFVTFDDHDS----VDKIVIQKYHTVNGHNCEVRKALSKQEMASASSSQRGRSGS 199
Query: 335 GGYRGRGGFQGRGGDPKSGDWVCPNPSCGNMNFARRNSCNQCNEPRPEDSRPSGGDFRGR 394
G + G RG
Sbjct: 200 GNF---------------------------------------------------GGGRGG 208
Query: 395 GYGGERGYRGRGGRGGDRGGYGGDRSGGGYGGDRSSGGGYSGDRSGGGYGGDRSGGGYGG 454
G+GG + GRGG RGG+GG R GGGYGG G+ D S G GG + G
Sbjct: 209 GFGGNDNF-GRGGNFSGRGGFGGSRGGGGYGGSGDGYNGFGNDGSNFGGGGSYNDFGNYN 267
Query: 455 DRGGGYGGDRGGGYGGDRGGGYGGDRGGYGGDRG-GGYGG--DRGGYGGDR 502
++ +G +GG +GG G YGG + R GGYGG YG R
Sbjct: 268 NQSSNFGPMKGGNFGGRSSGPYGGGGQYFAKPRNQGGYGGSSSSSSYGSGR 318
Score = 92.0 bits (227), Expect = 1e-18
Identities = 59/139 (42%), Positives = 71/139 (51%), Gaps = 16/139 (11%)
Query: 429 SSGGGYSGDRSGGGYGGDRSGGGYGGD----RGGGYGGDRGGGYGGDR-GGGYGGDRGGY 483
S+ G G +GG R GGG+GG+ RGG + G GG+GG R GGGYGG GY
Sbjct: 188 SASSSQRGRSGSGNFGGGR-GGGFGGNDNFGRGGNFSG--RGGFGGSRGGGGYGGSGDGY 244
Query: 484 G--GDRGGGYGGDRGGYGGDRGGYGGDRGGYGGDRGGYGGDRSRGGYGGDRGGGSGYGGD 541
G+ G +GG GG D G Y +G +GG G RS G YG GGG +
Sbjct: 245 NGFGNDGSNFGG--GGSYNDFGNYNNQSSNFGPMKGGNFGGRSSGPYG---GGGQYFAKP 299
Query: 542 RS-GGYGGDRSGGGYGGDR 559
R+ GGYGG S YG R
Sbjct: 300 RNQGGYGGSSSSSSYGSGR 318
Score = 92.0 bits (227), Expect = 1e-18
Identities = 56/135 (41%), Positives = 66/135 (48%), Gaps = 10/135 (7%)
Query: 399 ERGYRGRGGRGGDRGGYGGDRSGGGYGGDRSSGGGYSGDRSGGGYGGDRSGGGYGGDRGG 458
+RG G G GG RGG G G GG+ S GG+ G R GGGYGG SG GY G G
Sbjct: 193 QRGRSGSGNFGGGRGGGFGGNDNFGRGGNFSGRGGFGGSRGGGGYGG--SGDGYNG--FG 248
Query: 459 GYGGDRGGGYGGDRGGGYGGDRGGYGGDRGGGYGG-DRGGYGGDRGGYGGDRGGYGGDRG 517
G + GGG + G Y +G +GG +GG G YGG GG ++G
Sbjct: 249 NDGSNFGGGGSYNDFGNYNNQSSNFGPMKGGNFGGRSSGPYGG-----GGQYFAKPRNQG 303
Query: 518 GYGGDRSRGGYGGDR 532
GYGG S YG R
Sbjct: 304 GYGGSSSSSSYGSGR 318
Score = 92.0 bits (227), Expect = 1e-18
Identities = 58/130 (44%), Positives = 71/130 (54%), Gaps = 22/130 (16%)
Query: 447 RSGGG-YGGDRGGGYGGDRGGGYGGDRGGGYGGDRGGYGGDRGGGYGGDRGGYGGDRGGY 505
RSG G +GG RGGG+GG+ G RGG + G RGG+GG RGGG GYGG GY
Sbjct: 196 RSGSGNFGGGRGGGFGGNDNFG----RGGNFSG-RGGFGGSRGGG------GYGGSGDGY 244
Query: 506 GGDRGGYGGDRGGYGGDRSRGGYGGDRGGGSGYGGDRSGGYGGDRSGGGYGGDRGGGYGG 565
G +G D +GG S +G S +G + G +GG RS G YGG GG Y
Sbjct: 245 NG----FGNDGSNFGGGGSYNDFGNYNNQSSNFGPMKGGNFGG-RSSGPYGG--GGQYFA 297
Query: 566 ---DRGGYGG 572
++GGYGG
Sbjct: 298 KPRNQGGYGG 307
Score = 75.1 bits (183), Expect = 2e-13
Identities = 49/113 (43%), Positives = 59/113 (52%), Gaps = 17/113 (15%)
Query: 461 GGDRGGGYGGDRGGGYGGDRGGYGGDRGGGYGGDRGGYGGDRGGYGGDRGGYGGDRGGYG 520
G G +GG RGGG+GG+ +G RGG + G RGG+GG RGG GGYGG GY
Sbjct: 195 GRSGSGNFGGGRGGGFGGN-DNFG--RGGNFSG-RGGFGGSRGG-----GGYGGSGDGYN 245
Query: 521 GDRSRGGYGGDRGGGSGYGGDRSGGYGGDRSGGGYGGDRGGGYGG-DRGGYGG 572
G G G + GGG Y G Y S +G +GG +GG G YGG
Sbjct: 246 GF---GNDGSNFGGGGSYND--FGNYNNQSSN--FGPMKGGNFGGRSSGPYGG 291
Score = 58.5 bits (140), Expect = 2e-08
Identities = 31/68 (45%), Positives = 38/68 (55%), Gaps = 4/68 (5%)
Query: 517 GGYGGDRSRGGYGGDRGGGSGYGGDRSGGYGGDRSGGGYGGDRGG--GYGGDRGGYGGKM 574
G +GG R GG+GG+ G G GG+GG R GGGYGG G G+G D +GG
Sbjct: 200 GNFGGGRG-GGFGGNDNFGRGGNFSGRGGFGGSRGGGGYGGSGDGYNGFGNDGSNFGGG- 257
Query: 575 GGRNDYRN 582
G ND+ N
Sbjct: 258 GSYNDFGN 265
Score = 51.6 bits (122), Expect = 2e-06
Identities = 27/58 (46%), Positives = 33/58 (56%), Gaps = 3/58 (5%)
Query: 532 RGGGSGYGGDRSGGYGGDRSGGGYGGDRG-GGYGGDR--GGYGGKMGGRNDYRNDQRN 586
R G +GG R GG+GG+ + G G G GG+GG R GGYGG G N + ND N
Sbjct: 196 RSGSGNFGGGRGGGFGGNDNFGRGGNFSGRGGFGGSRGGGGYGGSGDGYNGFGNDGSN 253
Score = 38.9 bits (89), Expect = 0.013
Identities = 30/113 (26%), Positives = 41/113 (36%), Gaps = 22/113 (19%)
Query: 6 SYGQSGGEQQSYSTYGNPGSQGYGQASQSYSGYGQTTDSSYGQNYSGYSSYGQSYSQSYG 65
++G+ G G+ G GYG + Y+G+G G N+ G SY +G
Sbjct: 215 NFGRGGNFSGRGGFGGSRGGGGYGGSGDGYNGFGND-----GSNFGGGGSYND-----FG 264
Query: 66 GYENQKQS----------SYSQQPYNNQGQQQNMESSGSQGGRAPSYDQPDYG 108
Y NQ + S PY GQ +QGG S YG
Sbjct: 265 NYNNQSSNFGPMKGGNFGGRSSGPYGGGGQY--FAKPRNQGGYGGSSSSSSYG 315
Score = 37.0 bits (84), Expect = 0.051
Identities = 18/45 (40%), Positives = 22/45 (48%), Gaps = 11/45 (24%)
Query: 543 SGGYGGDRSGGGYGGDRGGGYGGD-----------RGGYGGKMGG 576
S G G +GG RGGG+GG+ RGG+GG GG
Sbjct: 190 SSSQRGRSGSGNFGGGRGGGFGGNDNFGRGGNFSGRGGFGGSRGG 234
Score = 33.5 bits (75), Expect = 0.56
Identities = 23/64 (35%), Positives = 29/64 (45%), Gaps = 7/64 (10%)
Query: 168 GEDNRGYGGSQGGGRGRGGYDKDGRGPMTGSSGGDRGGF----KNFGGHRDYGPRTDADS 223
G DN G GG+ GRGG+ G G SG GF NFGG Y + ++
Sbjct: 212 GNDNFGRGGNF---SGRGGFGGSRGGGGYGGSGDGYNGFGNDGSNFGGGGSYNDFGNYNN 268
Query: 224 ESDN 227
+S N
Sbjct: 269 QSSN 272
Score = 33.1 bits (74), Expect = 0.73
Identities = 40/127 (31%), Positives = 51/127 (40%), Gaps = 22/127 (17%)
Query: 136 HDSYSQNQ-QSYHSQR-ENYSHHTQDDRRDVSRYGEDNRGYGGSQ--GGGRGRG--GYDK 189
HDS + Q YH+ N +++++ RG GS GGGRG G G D
Sbjct: 156 HDSVDKIVIQKYHTVNGHNCEVRKALSKQEMASASSSQRGRSGSGNFGGGRGGGFGGNDN 215
Query: 190 DGRGPM---TGSSGGDRGGFKNFGGHRDYGPRTDADSESDNSDNNTIFVQGLGEGVSTDQ 246
GRG G GG RGG GG YG D + N +N G G S +
Sbjct: 216 FGRGGNFSGRGGFGGSRGG----GG---YGGSGDGYNGFGNDGSN------FGGGGSYND 262
Query: 247 VGEFFKQ 253
G + Q
Sbjct: 263 FGNYNNQ 269
Score = 30.8 bits (68), Expect = 3.6
Identities = 17/49 (34%), Positives = 25/49 (51%), Gaps = 4/49 (8%)
Query: 173 GYGGSQGGGRGRGGYDKDGRGPMTGSSGGDRGGFKNFGGHR----DYGP 217
G+GGS+GGG G D GS+ G G + +FG + ++GP
Sbjct: 227 GFGGSRGGGGYGGSGDGYNGFGNDGSNFGGGGSYNDFGNYNNQSSNFGP 275
>gi|212549553 interleukin enhancer binding factor 3 isoform d [Homo
sapiens]
Length = 898
Score = 99.8 bits (247), Expect = 6e-21
Identities = 78/232 (33%), Positives = 95/232 (40%), Gaps = 33/232 (14%)
Query: 374 NQCNEPRPEDSRPSGGDFRGRGYGGERGYRG-------RGGRGGDRGGYGGDRSGGGYGG 426
N+ P R GG RGRG G RG+ G G G GYGG+ + GY
Sbjct: 635 NEVPPPPNLRGRGRGGSIRGRGRG--RGFGGANHGGYMNAGAGYGSYGYGGNSATAGY-S 691
Query: 427 DRSSGGGYSGDRSGGGYGGDRSGGGYGGDRGGGYGGDRGGGYGGDRGGGYGGDRGGYGGD 486
S GG+SG+ SGGG GG GY G Y GD Y + G + +GG
Sbjct: 692 QFYSNGGHSGNASGGGGGGGGGSSGY----GSYYQGD---NYNSPVPPKHAGKKQPHGGQ 744
Query: 487 RGGGYGGDRGGYGGDRGGYG-----------GDRGGYGGDRGGYGGDRSRGGYGGDRGGG 535
+ YG + G + Y G + GY +G Y S GG GGG
Sbjct: 745 QKPSYGSGYQSHQGQQQSYNQSPYSNYGPPQGKQKGYNHGQGSYSYSNSYNSPGG--GGG 802
Query: 536 SGYGGDRSGGYGGD--RSGGGYGGDRGGGYG-GDRGGYGGKMGGRNDYRNDQ 584
S Y + Y G RSGG G G Y G GGYGG GG + Y+ Q
Sbjct: 803 SDYNYESKFNYSGSGGRSGGNSYGSGGASYNPGSHGGYGGGSGGGSSYQGKQ 854
Score = 64.7 bits (156), Expect = 2e-10
Identities = 61/230 (26%), Positives = 93/230 (40%), Gaps = 40/230 (17%)
Query: 2 SDSGSYGQSGGEQQSYSTYGNPGSQGYGQ--ASQSYSGYGQTTDSSYGQNYSGYSSY--G 57
++ G Y +G SY GN + GY Q ++ +SG G SGY SY G
Sbjct: 664 ANHGGYMNAGAGYGSYGYGGNSATAGYSQFYSNGGHSGNASGGGGGGGGGSSGYGSYYQG 723
Query: 58 QSYS-----------QSYGGYENQKQSSYSQQPYNNQGQQQNMESSGSQGGRAPSYDQPD 106
+Y+ Q +GG Q++ SY ++QGQQQ SY+Q
Sbjct: 724 DNYNSPVPPKHAGKKQPHGG---QQKPSYGSGYQSHQGQQQ-------------SYNQSP 767
Query: 107 YGQQ-DSYDQQSGYDQHQGSYDEQSNYDQQHDSYSQNQQSYHSQRENYSHHTQDDRRDVS 165
Y +Q GY+ QGSY +Y ++S S ++ +++ R +
Sbjct: 768 YSNYGPPQGKQKGYNHGQGSY----SYSNSYNSPGGGGGSDYNYESKFNYSGSGGRSGGN 823
Query: 166 RYGED----NRGYGGSQGGGRGRGGYDKDGRGPMTGSSGGDRGGFKNFGG 211
YG N G G GGG G G + +G + S+ G +N+ G
Sbjct: 824 SYGSGGASYNPGSHGGYGGGSGGGSSYQGKQGGYSQSNYNSPGSGQNYSG 873
Score = 58.2 bits (139), Expect = 2e-08
Identities = 51/177 (28%), Positives = 74/177 (41%), Gaps = 15/177 (8%)
Query: 47 GQNYSGYSSYGQSYSQSYGGYENQKQSSYSQQPYNNQGQQQNMESSGSQGGRAPSYDQPD 106
G N+ GY + G Y SYG N + YSQ Y+N G N S G GG S
Sbjct: 663 GANHGGYMNAGAGYG-SYGYGGNSATAGYSQF-YSNGGHSGNA-SGGGGGGGGGSSGYGS 719
Query: 107 YGQQDSYDQQSGYDQHQGSYDEQSNYDQQHDSYSQNQQSYHSQRENYSHHTQDDRRDVSR 166
Y Q D+Y+ +H G +Q + QQ SY QS+ Q+++Y+ + S
Sbjct: 720 YYQGDNYNSPVP-PKHAGK--KQPHGGQQKPSYGSGYQSHQGQQQSYN------QSPYSN 770
Query: 167 YGEDNRGYGGSQGGGRGRGGYDKDGRGPMTGSSGGDRGGFKNFGGHRDYGPRTDADS 223
YG G +G G+G Y G GG +++ + G R+ +S
Sbjct: 771 YGPPQ---GKQKGYNHGQGSYSYSNSYNSPGGGGGSDYNYESKFNYSGSGGRSGGNS 824
Score = 49.3 bits (116), Expect = 1e-05
Identities = 49/153 (32%), Positives = 65/153 (42%), Gaps = 23/153 (15%)
Query: 2 SDSGSYGQSGGEQQSY-----STYGNP-GSQ---GYGQASQSYS------GYGQTTDSSY 46
S Y G+QQSY S YG P G Q +GQ S SYS G G +D +Y
Sbjct: 748 SYGSGYQSHQGQQQSYNQSPYSNYGPPQGKQKGYNHGQGSYSYSNSYNSPGGGGGSDYNY 807
Query: 47 GQNYSGYSSYGQSYSQSYGGYENQKQSSYSQQPYNNQGQQQNMESS--GSQGGRAPS-YD 103
++ S G+S SYG +SY+ + G SS G QGG + S Y+
Sbjct: 808 ESKFNYSGSGGRSGGNSYGS----GGASYNPGSHGGYGGGSGGGSSYQGKQGGYSQSNYN 863
Query: 104 QPDYGQQDSYDQQSGYDQHQGSYDEQSNYDQQH 136
P GQ S S Y QG Y +++ +
Sbjct: 864 SPGSGQNYS-GPPSSYQSSQGGYGRNADHSMNY 895
Score = 43.5 bits (101), Expect = 5e-04
Identities = 38/88 (43%), Positives = 43/88 (48%), Gaps = 18/88 (20%)
Query: 4 SGSYGQSGGEQQSYSTYG---NPGSQG-YGQASQSYSGY----GQTTDSSY-----GQNY 50
SGS G+SGG SY + G NPGS G YG S S Y G + S+Y GQNY
Sbjct: 814 SGSGGRSGGN--SYGSGGASYNPGSHGGYGGGSGGGSSYQGKQGGYSQSNYNSPGSGQNY 871
Query: 51 SGYSSYGQSYSQSYGGYENQKQSSYSQQ 78
SG S SY S GGY S + Q
Sbjct: 872 SGPPS---SYQSSQGGYGRNADHSMNYQ 896
>gi|24234750 interleukin enhancer binding factor 3 isoform a [Homo
sapiens]
Length = 894
Score = 99.8 bits (247), Expect = 6e-21
Identities = 78/232 (33%), Positives = 95/232 (40%), Gaps = 33/232 (14%)
Query: 374 NQCNEPRPEDSRPSGGDFRGRGYGGERGYRG-------RGGRGGDRGGYGGDRSGGGYGG 426
N+ P R GG RGRG G RG+ G G G GYGG+ + GY
Sbjct: 631 NEVPPPPNLRGRGRGGSIRGRGRG--RGFGGANHGGYMNAGAGYGSYGYGGNSATAGY-S 687
Query: 427 DRSSGGGYSGDRSGGGYGGDRSGGGYGGDRGGGYGGDRGGGYGGDRGGGYGGDRGGYGGD 486
S GG+SG+ SGGG GG GY G Y GD Y + G + +GG
Sbjct: 688 QFYSNGGHSGNASGGGGGGGGGSSGY----GSYYQGD---NYNSPVPPKHAGKKQPHGGQ 740
Query: 487 RGGGYGGDRGGYGGDRGGYG-----------GDRGGYGGDRGGYGGDRSRGGYGGDRGGG 535
+ YG + G + Y G + GY +G Y S GG GGG
Sbjct: 741 QKPSYGSGYQSHQGQQQSYNQSPYSNYGPPQGKQKGYNHGQGSYSYSNSYNSPGG--GGG 798
Query: 536 SGYGGDRSGGYGGD--RSGGGYGGDRGGGYG-GDRGGYGGKMGGRNDYRNDQ 584
S Y + Y G RSGG G G Y G GGYGG GG + Y+ Q
Sbjct: 799 SDYNYESKFNYSGSGGRSGGNSYGSGGASYNPGSHGGYGGGSGGGSSYQGKQ 850
Score = 64.7 bits (156), Expect = 2e-10
Identities = 61/230 (26%), Positives = 93/230 (40%), Gaps = 40/230 (17%)
Query: 2 SDSGSYGQSGGEQQSYSTYGNPGSQGYGQ--ASQSYSGYGQTTDSSYGQNYSGYSSY--G 57
++ G Y +G SY GN + GY Q ++ +SG G SGY SY G
Sbjct: 660 ANHGGYMNAGAGYGSYGYGGNSATAGYSQFYSNGGHSGNASGGGGGGGGGSSGYGSYYQG 719
Query: 58 QSYS-----------QSYGGYENQKQSSYSQQPYNNQGQQQNMESSGSQGGRAPSYDQPD 106
+Y+ Q +GG Q++ SY ++QGQQQ SY+Q
Sbjct: 720 DNYNSPVPPKHAGKKQPHGG---QQKPSYGSGYQSHQGQQQ-------------SYNQSP 763
Query: 107 YGQQ-DSYDQQSGYDQHQGSYDEQSNYDQQHDSYSQNQQSYHSQRENYSHHTQDDRRDVS 165
Y +Q GY+ QGSY +Y ++S S ++ +++ R +
Sbjct: 764 YSNYGPPQGKQKGYNHGQGSY----SYSNSYNSPGGGGGSDYNYESKFNYSGSGGRSGGN 819
Query: 166 RYGED----NRGYGGSQGGGRGRGGYDKDGRGPMTGSSGGDRGGFKNFGG 211
YG N G G GGG G G + +G + S+ G +N+ G
Sbjct: 820 SYGSGGASYNPGSHGGYGGGSGGGSSYQGKQGGYSQSNYNSPGSGQNYSG 869
Score = 58.2 bits (139), Expect = 2e-08
Identities = 51/177 (28%), Positives = 74/177 (41%), Gaps = 15/177 (8%)
Query: 47 GQNYSGYSSYGQSYSQSYGGYENQKQSSYSQQPYNNQGQQQNMESSGSQGGRAPSYDQPD 106
G N+ GY + G Y SYG N + YSQ Y+N G N S G GG S
Sbjct: 659 GANHGGYMNAGAGYG-SYGYGGNSATAGYSQF-YSNGGHSGNA-SGGGGGGGGGSSGYGS 715
Query: 107 YGQQDSYDQQSGYDQHQGSYDEQSNYDQQHDSYSQNQQSYHSQRENYSHHTQDDRRDVSR 166
Y Q D+Y+ +H G +Q + QQ SY QS+ Q+++Y+ + S
Sbjct: 716 YYQGDNYNSPVP-PKHAGK--KQPHGGQQKPSYGSGYQSHQGQQQSYN------QSPYSN 766
Query: 167 YGEDNRGYGGSQGGGRGRGGYDKDGRGPMTGSSGGDRGGFKNFGGHRDYGPRTDADS 223
YG G +G G+G Y G GG +++ + G R+ +S
Sbjct: 767 YGPPQ---GKQKGYNHGQGSYSYSNSYNSPGGGGGSDYNYESKFNYSGSGGRSGGNS 820
Score = 49.3 bits (116), Expect = 1e-05
Identities = 49/153 (32%), Positives = 65/153 (42%), Gaps = 23/153 (15%)
Query: 2 SDSGSYGQSGGEQQSY-----STYGNP-GSQ---GYGQASQSYS------GYGQTTDSSY 46
S Y G+QQSY S YG P G Q +GQ S SYS G G +D +Y
Sbjct: 744 SYGSGYQSHQGQQQSYNQSPYSNYGPPQGKQKGYNHGQGSYSYSNSYNSPGGGGGSDYNY 803
Query: 47 GQNYSGYSSYGQSYSQSYGGYENQKQSSYSQQPYNNQGQQQNMESS--GSQGGRAPS-YD 103
++ S G+S SYG +SY+ + G SS G QGG + S Y+
Sbjct: 804 ESKFNYSGSGGRSGGNSYGS----GGASYNPGSHGGYGGGSGGGSSYQGKQGGYSQSNYN 859
Query: 104 QPDYGQQDSYDQQSGYDQHQGSYDEQSNYDQQH 136
P GQ S S Y QG Y +++ +
Sbjct: 860 SPGSGQNYS-GPPSSYQSSQGGYGRNADHSMNY 891
Score = 43.5 bits (101), Expect = 5e-04
Identities = 38/88 (43%), Positives = 43/88 (48%), Gaps = 18/88 (20%)
Query: 4 SGSYGQSGGEQQSYSTYG---NPGSQG-YGQASQSYSGY----GQTTDSSY-----GQNY 50
SGS G+SGG SY + G NPGS G YG S S Y G + S+Y GQNY
Sbjct: 810 SGSGGRSGGN--SYGSGGASYNPGSHGGYGGGSGGGSSYQGKQGGYSQSNYNSPGSGQNY 867
Query: 51 SGYSSYGQSYSQSYGGYENQKQSSYSQQ 78
SG S SY S GGY S + Q
Sbjct: 868 SGPPS---SYQSSQGGYGRNADHSMNYQ 892
>gi|242117971 RNA binding motif protein, X-linked-like 1 [Homo
sapiens]
Length = 390
Score = 98.6 bits (244), Expect = 1e-20
Identities = 124/395 (31%), Positives = 144/395 (36%), Gaps = 62/395 (15%)
Query: 242 VSTDQVGEFFKQIGIIKTNKKTGKPMINLY---------TDKDTGKPKGEATVSFDDPPS 292
V D+ G+ F +TN+K + + Y D++T K +G A V+F+ P
Sbjct: 2 VEADRPGKLFIGGLNTETNEKALETVFGKYGRIVEVLLIKDRETNKSRGFAFVTFESPAD 61
Query: 293 AKAAIDWFDGKEFHGNIIKVSFATRRPEFMRG-GGSGGGRRGRGGYR----GRGGFQGRG 347
AK A +GK G IKV AT +P F RG G R RG R GRGG G
Sbjct: 62 AKDAARDMNGKSLDGKAIKVEQAT-KPSFERGRHGPPPPPRSRGPPRGFGAGRGGSGGTR 120
Query: 348 GDPKSGDWVCPNPSCGNMNFA--------RRNSCNQCNEPRPEDSRPSGGDFRGRGYGGE 399
G P G + N N + +R + P P+ S PSG G GG
Sbjct: 121 GPPSRGGHMDDGGYSMNFNMSSSRGPLPVKRGPPPRSGGPSPKRSAPSGLVRSSSGMGGR 180
Query: 400 RGY-RGRGGRGGD---------RGGYGGDRSGGGYGGDRSSGGGYSGDRSGGGYG---GD 446
RGR GG R Y R G D S Y R Y D
Sbjct: 181 APLSRGRDSYGGPPRREPLPSRRDVYLSPRDDGYSTKDSYSSRDYPSSRDTRDYAPPPRD 240
Query: 447 RSGGGYGGDR------GGGYGGDRGGGYGGDR-------GGGYGGDRGGYGGDRGGGY-G 492
+ YG GY GDR GYG DR GG Y YG R
Sbjct: 241 YTYRDYGHSSSRDDYPSRGY-GDR-DGYGRDRDYSDHPSGGSYRDSYESYGNSRSAPLTR 298
Query: 493 GDRGGYGGDR--GGYGGDRGGYGGDRGGYGGDRSRGGYGGDRGGGSGYGGDRS--GGYGG 548
G YGG Y R GYGG R Y RS DR G G S GY
Sbjct: 299 GPPPSYGGSSRYDDYSSSRDGYGGSRDSYSSSRSDLYSSCDRVGRQERGLPPSVERGYPS 358
Query: 549 DR---SGGGYGGDRGGGYGGDRGGYGGKMGGRNDY 580
R S G RG G GG R G GGR+ Y
Sbjct: 359 SRDSYSSSSRGAPRGAGPGGSRSDRG---GGRSRY 390
Score = 46.2 bits (108), Expect = 8e-05
Identities = 46/185 (24%), Positives = 66/185 (35%), Gaps = 43/185 (23%)
Query: 52 GYSSYGQSYSQSYGGYENQKQSSYSQQP----YNNQGQQQNMESSGSQGGRAPSYDQPDY 107
GYS+ S+ Y + + Y+ P Y + G + + S+G Y
Sbjct: 213 GYSTKDSYSSRDYPSSRDTRD--YAPPPRDYTYRDYGHSSSRDDYPSRG----------Y 260
Query: 108 GQQDSYDQQSGYDQHQ--GSY-DEQSNY------------------DQQHDSYSQNQQSY 146
G +D Y + Y H GSY D +Y ++D YS ++ Y
Sbjct: 261 GDRDGYGRDRDYSDHPSGGSYRDSYESYGNSRSAPLTRGPPPSYGGSSRYDDYSSSRDGY 320
Query: 147 HSQRENYSHHTQDDRRDVSRYGEDNRGYGGS--QGGGRGRGGYDKDGRGPMTGSSGG--- 201
R++YS D R G RG S +G R Y RG G+ G
Sbjct: 321 GGSRDSYSSSRSDLYSSCDRVGRQERGLPPSVERGYPSSRDSYSSSSRGAPRGAGPGGSR 380
Query: 202 -DRGG 205
DRGG
Sbjct: 381 SDRGG 385
Score = 35.0 bits (79), Expect = 0.19
Identities = 75/343 (21%), Positives = 108/343 (31%), Gaps = 91/343 (26%)
Query: 24 GSQGYGQASQSYSGYGQTTDSSYGQNYSGYSSYG----QSYSQSYGGYENQKQSSYSQQP 79
G G G S G D Y N++ SS G + G + K+S+ S
Sbjct: 112 GRGGSGGTRGPPSRGGHMDDGGYSMNFNMSSSRGPLPVKRGPPPRSGGPSPKRSAPSGL- 170
Query: 80 YNNQGQQQNMESSGSQGGRAPSYDQPDYGQQDSYDQQSGYDQHQGSYDEQSNYDQQHDSY 139
+ SS GGRAP +DSY G + + D Y
Sbjct: 171 ---------VRSSSGMGGRAPLSRG-----RDSY----------GGPPRREPLPSRRDVY 206
Query: 140 SQNQQSYHSQRENYSHHTQDDRRDVSRYGEDNR-------GYGGSQGGGRGRGGYDKDGR 192
+ +S +++YS RD Y R G+ S+ RG D+DG
Sbjct: 207 LSPRDDGYSTKDSYSSRDYPSSRDTRDYAPPPRDYTYRDYGHSSSRDDYPSRGYGDRDGY 266
Query: 193 GPMTG-----SSGGDRGGFKNFGGHR----------DYGPRTDADSESDNSDNNTIFVQG 237
G S G R ++++G R YG + D S + D
Sbjct: 267 GRDRDYSDHPSGGSYRDSYESYGNSRSAPLTRGPPPSYGGSSRYDDYSSSRD-------- 318
Query: 238 LGEGVSTDQVGEFFKQIGIIKTNKKTGKPMINLYTDKDTGKPKGEATVSFDDPPSAKAAI 297
G G S D + + + + G+ L + G P + S S++ A
Sbjct: 319 -GYGGSRDSYSS--SRSDLYSSCDRVGRQERGLPPSVERGYPSSRDSYS----SSSRGA- 370
Query: 298 DWFDGKEFHGNIIKVSFATRRPEFMRGGGSGGGRRGRGGYRGR 340
RG G GG R RGG R R
Sbjct: 371 ------------------------PRGAGPGGSRSDRGGGRSR 389
Score = 33.1 bits (74), Expect = 0.73
Identities = 31/118 (26%), Positives = 40/118 (33%), Gaps = 21/118 (17%)
Query: 3 DSGSYGQSGGEQQSYSTYGNP--------------GSQGYGQASQSYSGYGQTTDSSYGQ 48
D + G + SY +YGN GS Y S S GYG + DS
Sbjct: 271 DYSDHPSGGSYRDSYESYGNSRSAPLTRGPPPSYGGSSRYDDYSSSRDGYGGSRDSYSSS 330
Query: 49 NYSGYSSYGQSYSQSYG-------GYENQKQSSYSQQPYNNQGQQQNMESSGSQGGRA 99
YSS + Q G GY + + S S +G S GGR+
Sbjct: 331 RSDLYSSCDRVGRQERGLPPSVERGYPSSRDSYSSSSRGAPRGAGPGGSRSDRGGGRS 388
>gi|21361809 RNA binding motif protein, X-linked-like 1 [Homo
sapiens]
Length = 390
Score = 98.6 bits (244), Expect = 1e-20
Identities = 124/395 (31%), Positives = 144/395 (36%), Gaps = 62/395 (15%)
Query: 242 VSTDQVGEFFKQIGIIKTNKKTGKPMINLY---------TDKDTGKPKGEATVSFDDPPS 292
V D+ G+ F +TN+K + + Y D++T K +G A V+F+ P
Sbjct: 2 VEADRPGKLFIGGLNTETNEKALETVFGKYGRIVEVLLIKDRETNKSRGFAFVTFESPAD 61
Query: 293 AKAAIDWFDGKEFHGNIIKVSFATRRPEFMRG-GGSGGGRRGRGGYR----GRGGFQGRG 347
AK A +GK G IKV AT +P F RG G R RG R GRGG G
Sbjct: 62 AKDAARDMNGKSLDGKAIKVEQAT-KPSFERGRHGPPPPPRSRGPPRGFGAGRGGSGGTR 120
Query: 348 GDPKSGDWVCPNPSCGNMNFA--------RRNSCNQCNEPRPEDSRPSGGDFRGRGYGGE 399
G P G + N N + +R + P P+ S PSG G GG
Sbjct: 121 GPPSRGGHMDDGGYSMNFNMSSSRGPLPVKRGPPPRSGGPSPKRSAPSGLVRSSSGMGGR 180
Query: 400 RGY-RGRGGRGGD---------RGGYGGDRSGGGYGGDRSSGGGYSGDRSGGGYG---GD 446
RGR GG R Y R G D S Y R Y D
Sbjct: 181 APLSRGRDSYGGPPRREPLPSRRDVYLSPRDDGYSTKDSYSSRDYPSSRDTRDYAPPPRD 240
Query: 447 RSGGGYGGDR------GGGYGGDRGGGYGGDR-------GGGYGGDRGGYGGDRGGGY-G 492
+ YG GY GDR GYG DR GG Y YG R
Sbjct: 241 YTYRDYGHSSSRDDYPSRGY-GDR-DGYGRDRDYSDHPSGGSYRDSYESYGNSRSAPLTR 298
Query: 493 GDRGGYGGDR--GGYGGDRGGYGGDRGGYGGDRSRGGYGGDRGGGSGYGGDRS--GGYGG 548
G YGG Y R GYGG R Y RS DR G G S GY
Sbjct: 299 GPPPSYGGSSRYDDYSSSRDGYGGSRDSYSSSRSDLYSSCDRVGRQERGLPPSVERGYPS 358
Query: 549 DR---SGGGYGGDRGGGYGGDRGGYGGKMGGRNDY 580
R S G RG G GG R G GGR+ Y
Sbjct: 359 SRDSYSSSSRGAPRGAGPGGSRSDRG---GGRSRY 390
Score = 46.2 bits (108), Expect = 8e-05
Identities = 46/185 (24%), Positives = 66/185 (35%), Gaps = 43/185 (23%)
Query: 52 GYSSYGQSYSQSYGGYENQKQSSYSQQP----YNNQGQQQNMESSGSQGGRAPSYDQPDY 107
GYS+ S+ Y + + Y+ P Y + G + + S+G Y
Sbjct: 213 GYSTKDSYSSRDYPSSRDTRD--YAPPPRDYTYRDYGHSSSRDDYPSRG----------Y 260
Query: 108 GQQDSYDQQSGYDQHQ--GSY-DEQSNY------------------DQQHDSYSQNQQSY 146
G +D Y + Y H GSY D +Y ++D YS ++ Y
Sbjct: 261 GDRDGYGRDRDYSDHPSGGSYRDSYESYGNSRSAPLTRGPPPSYGGSSRYDDYSSSRDGY 320
Query: 147 HSQRENYSHHTQDDRRDVSRYGEDNRGYGGS--QGGGRGRGGYDKDGRGPMTGSSGG--- 201
R++YS D R G RG S +G R Y RG G+ G
Sbjct: 321 GGSRDSYSSSRSDLYSSCDRVGRQERGLPPSVERGYPSSRDSYSSSSRGAPRGAGPGGSR 380
Query: 202 -DRGG 205
DRGG
Sbjct: 381 SDRGG 385
Score = 35.0 bits (79), Expect = 0.19
Identities = 75/343 (21%), Positives = 108/343 (31%), Gaps = 91/343 (26%)
Query: 24 GSQGYGQASQSYSGYGQTTDSSYGQNYSGYSSYG----QSYSQSYGGYENQKQSSYSQQP 79
G G G S G D Y N++ SS G + G + K+S+ S
Sbjct: 112 GRGGSGGTRGPPSRGGHMDDGGYSMNFNMSSSRGPLPVKRGPPPRSGGPSPKRSAPSGL- 170
Query: 80 YNNQGQQQNMESSGSQGGRAPSYDQPDYGQQDSYDQQSGYDQHQGSYDEQSNYDQQHDSY 139
+ SS GGRAP +DSY G + + D Y
Sbjct: 171 ---------VRSSSGMGGRAPLSRG-----RDSY----------GGPPRREPLPSRRDVY 206
Query: 140 SQNQQSYHSQRENYSHHTQDDRRDVSRYGEDNR-------GYGGSQGGGRGRGGYDKDGR 192
+ +S +++YS RD Y R G+ S+ RG D+DG
Sbjct: 207 LSPRDDGYSTKDSYSSRDYPSSRDTRDYAPPPRDYTYRDYGHSSSRDDYPSRGYGDRDGY 266
Query: 193 GPMTG-----SSGGDRGGFKNFGGHR----------DYGPRTDADSESDNSDNNTIFVQG 237
G S G R ++++G R YG + D S + D
Sbjct: 267 GRDRDYSDHPSGGSYRDSYESYGNSRSAPLTRGPPPSYGGSSRYDDYSSSRD-------- 318
Query: 238 LGEGVSTDQVGEFFKQIGIIKTNKKTGKPMINLYTDKDTGKPKGEATVSFDDPPSAKAAI 297
G G S D + + + + G+ L + G P + S S++ A
Sbjct: 319 -GYGGSRDSYSS--SRSDLYSSCDRVGRQERGLPPSVERGYPSSRDSYS----SSSRGA- 370
Query: 298 DWFDGKEFHGNIIKVSFATRRPEFMRGGGSGGGRRGRGGYRGR 340
RG G GG R RGG R R
Sbjct: 371 ------------------------PRGAGPGGSRSDRGGGRSR 389
Score = 33.1 bits (74), Expect = 0.73
Identities = 31/118 (26%), Positives = 40/118 (33%), Gaps = 21/118 (17%)
Query: 3 DSGSYGQSGGEQQSYSTYGNP--------------GSQGYGQASQSYSGYGQTTDSSYGQ 48
D + G + SY +YGN GS Y S S GYG + DS
Sbjct: 271 DYSDHPSGGSYRDSYESYGNSRSAPLTRGPPPSYGGSSRYDDYSSSRDGYGGSRDSYSSS 330
Query: 49 NYSGYSSYGQSYSQSYG-------GYENQKQSSYSQQPYNNQGQQQNMESSGSQGGRA 99
YSS + Q G GY + + S S +G S GGR+
Sbjct: 331 RSDLYSSCDRVGRQERGLPPSVERGYPSSRDSYSSSSRGAPRGAGPGGSRSDRGGGRS 388
>gi|56699409 RNA binding motif protein, X-linked [Homo sapiens]
Length = 391
Score = 97.8 bits (242), Expect = 2e-20
Identities = 122/402 (30%), Positives = 142/402 (35%), Gaps = 75/402 (18%)
Query: 242 VSTDQVGEFFKQIGIIKTNKKTGKPMINLY---------TDKDTGKPKGEATVSFDDPPS 292
V D+ G+ F +TN+K + + Y D++T K +G A V+F+ P
Sbjct: 2 VEADRPGKLFIGGLNTETNEKALEAVFGKYGRIVEVLLMKDRETNKSRGFAFVTFESPAD 61
Query: 293 AKAAIDWFDGKEFHGNIIKVSFATRRPEFMRG-----------GGSGGGRRGRGGYRGRG 341
AK A +GK G IKV AT +P F G G G R GRGG G
Sbjct: 62 AKDAARDMNGKSLDGKAIKVEQAT-KPSFESGRRGPPPPPRSRGPPRGLRGGRGGSGGTR 120
Query: 342 GFQGRGGDPKSGDWVCPNPSCGNMNF----------ARRNSCNQCNEPRPEDSRPSGGDF 391
G RGG G + +MNF +R + P P+ S PSG
Sbjct: 121 GPPSRGGHMDDGGY--------SMNFNMSSSRGPLPVKRGPPPRSGGPPPKRSAPSGPVR 172
Query: 392 RGRGYGGERGY-RGRGGRGGD---------RGGYGGDRSGGGYGGDRSSGGGYSGDRSGG 441
G GG RGR GG R Y R G D S Y R
Sbjct: 173 SSSGMGGRAPVSRGRDSYGGPPRREPLPSRRDVYLSPRDDGYSTKDSYSSRDYPSSRDTR 232
Query: 442 GYG---GDRSGGGYGGDRGGGYGGDRG----GGYGGDR-------GGGYGGDRGGYGGDR 487
Y D + YG RG GYG DR GG Y YG R
Sbjct: 233 DYAPPPRDYTYRDYGHSSSRDDYPSRGYSDRDGYGRDRDYSDHPSGGSYRDSYESYGNSR 292
Query: 488 GG-GYGGDRGGYGGDR--GGYGGDRGGYGGDRGGYGGDRS-RGGYGGDRGGGS--GYGGD 541
G YGG Y R GYGG R Y RS G DR G G
Sbjct: 293 SAPPTRGPPPSYGGSSRYDDYSSSRDGYGGSRDSYSSSRSDLYSSGRDRVGRQERGLPPS 352
Query: 542 RSGGYGGDR---SGGGYGGDRGGGYGGDRGGYGGKMGGRNDY 580
GY R S G RGGG GG R G GGR+ Y
Sbjct: 353 MERGYPPPRDSYSSSSRGAPRGGGRGGSRSDRG---GGRSRY 391
Score = 46.2 bits (108), Expect = 8e-05
Identities = 51/196 (26%), Positives = 70/196 (35%), Gaps = 25/196 (12%)
Query: 20 YGNPGSQGYGQ----ASQSYSGYGQTTDSSYGQNYSGYSSYGQSYSQSYGGYENQKQSSY 75
Y +P GY +S+ Y T D + Y YG S S+ ++ Y
Sbjct: 206 YLSPRDDGYSTKDSYSSRDYPSSRDTRDYAPPPRDYTYRDYGHSSSR-----DDYPSRGY 260
Query: 76 SQQPYNNQGQQQNMESSGSQGGRAPSYDQPDYGQQDSYDQQSGYDQHQGSYDEQSNYDQQ 135
S + + G+ ++ S G SY+ YG S G G +Y
Sbjct: 261 SDR--DGYGRDRDYSDHPSGGSYRDSYES--YGNSRSAPPTRGPPPSYGGSSRYDDYSSS 316
Query: 136 HDSYSQNQQSYHSQRENYSHHTQDDRRDVSRYGEDNRGYGGS--QGGGRGRGGYDKDGRG 193
D Y ++ SY S R + +D R G RG S +G R Y RG
Sbjct: 317 RDGYGGSRDSYSSSRSDLYSSGRD------RVGRQERGLPPSMERGYPPPRDSYSSSSRG 370
Query: 194 -PMTGSSGG---DRGG 205
P G GG DRGG
Sbjct: 371 APRGGGRGGSRSDRGG 386
Score = 43.1 bits (100), Expect = 7e-04
Identities = 65/287 (22%), Positives = 96/287 (33%), Gaps = 53/287 (18%)
Query: 24 GSQGYGQASQSYSGYGQTTDSSYGQNYSGYSSYGQSYSQSYGGYENQKQSSYSQQPYNNQ 83
G G G S G D Y N++ SS G + P
Sbjct: 112 GRGGSGGTRGPPSRGGHMDDGGYSMNFNMSSSRGPL------PVKRGPPPRSGGPPPKRS 165
Query: 84 GQQQNMESSGSQGGRAP-SYDQPDYG------------------QQDSYDQQSGYDQHQ- 123
+ SS GGRAP S + YG + D Y + Y
Sbjct: 166 APSGPVRSSSGMGGRAPVSRGRDSYGGPPRREPLPSRRDVYLSPRDDGYSTKDSYSSRDY 225
Query: 124 GSYDEQSNYDQQHDSYSQNQQSYHSQRENYSHHTQDDRRDVSRYGEDNRGYGGSQGGGRG 183
S + +Y Y+ + S R++Y DR YG D R Y GG
Sbjct: 226 PSSRDTRDYAPPPRDYTYRDYGHSSSRDDYPSRGYSDR---DGYGRD-RDYSDHPSGGSY 281
Query: 184 RGGYDKDG--------RGPMTGSSGGDRGGFKNFGGHRD-YGPRTDADSESDNSDNNTIF 234
R Y+ G RGP G R + ++ RD YG D S +S + ++
Sbjct: 282 RDSYESYGNSRSAPPTRGPPPSYGGSSR--YDDYSSSRDGYGGSRD----SYSSSRSDLY 335
Query: 235 VQGLGEGVSTDQVGEFFKQIGIIKTNKKTGKPMINLYTDKDTGKPKG 281
G D+VG ++ G+ + ++ P + Y+ G P+G
Sbjct: 336 SSG------RDRVGR--QERGLPPSMERGYPPPRDSYSSSSRGAPRG 374
>gi|119395750 keratin 1 [Homo sapiens]
Length = 644
Score = 96.7 bits (239), Expect = 5e-20
Identities = 69/164 (42%), Positives = 80/164 (48%), Gaps = 23/164 (14%)
Query: 394 RGYGGERGYRGRGG-RGGDRGGYGGDRSGGGYGGDRSSGGGYSGDRSGGGYGGDRSGGGY 452
R + GYR GG G G R RS GGG GGG G +GGG+
Sbjct: 3 RQFSSRSGYRSGGGFSSGSAGIINYQRRTTSSSTRRSGGGGGRFSSCGGGGGSFGAGGGF 62
Query: 453 GGDRGGGYGGDRGGGYGGDRGGGYGGDRGGYGGDRGGGYGGDRGGYGGDRGGYGGDRGGY 512
G GG + RGGG G G+GG GYGG GG+GG GG+G GG+
Sbjct: 63 GSRSLVNLGGSKSISISVARGGGRGS---GFGG----GYGG--GGFGG--GGFG--GGGF 109
Query: 513 GGDRGGYGGDRSRGGYGGDRGGGSGYGGDRSGGYGGDRSGGGYG 556
GG GG GG GG+GG GG G+GG GG+GG GGGYG
Sbjct: 110 GG--GGIGG----GGFGGFGSGGGGFGG---GGFGGGGYGGGYG 144
Score = 96.3 bits (238), Expect = 7e-20
Identities = 61/125 (48%), Positives = 62/125 (49%), Gaps = 10/125 (8%)
Query: 448 SGGGYGGDRGGGYGGDRGGGYGGDRGGGYGGDRGGYGGDRGGGYGGDRGGYGGDRGGYGG 507
SGGG G GGGYG GG G GG YG GG GG G YG YG G YG
Sbjct: 513 SGGGSRGGGGGGYGS--GGSSYGSGGGSYGSGGGGGGGR--GSYGSGGSSYGSGGGSYGS 568
Query: 508 DRGGYGGDRGGYGGDRSRGGY-GGDRGGGSGYGGDRSGGYGGDRSGGGYGGDRGGGYGGD 566
GG GG G YG S GGY GG GGG G G R G GG SGG GG RG GG
Sbjct: 569 --GGGGGGHGSYGSGSSSGGYRGGSGGGGGGSSGGR--GSGGGSSGGSIGG-RGSSSGGV 623
Query: 567 RGGYG 571
+ G
Sbjct: 624 KSSGG 628
Score = 92.0 bits (227), Expect = 1e-18
Identities = 61/137 (44%), Positives = 64/137 (46%), Gaps = 15/137 (10%)
Query: 409 GGDRGGYGGDRSGGGYGGDRSS----GGGY-SGDRSGGGYGGDRSGGGYGGDRGGGYGGD 463
GG RGG GGGYG SS GG Y SG GGG G SGG G GG YG
Sbjct: 515 GGSRGG-----GGGGYGSGGSSYGSGGGSYGSGGGGGGGRGSYGSGGSSYGSGGGSYGS- 568
Query: 464 RGGGYGGDRGGGYGGDRGGYGGDRGGGYGGDRGGYGGDRGGYGGDRGGYGGDRGGYGGDR 523
GGG GG G G GGY G GGG GG GG G G GG GG G GG +
Sbjct: 569 -GGGGGGHGSYGSGSSSGGYRGGSGGGGGGSSGGRGSGGGSSGGSIGGRGSSSGGV---K 624
Query: 524 SRGGYGGDRGGGSGYGG 540
S GG + + Y G
Sbjct: 625 SSGGSSSVKFVSTTYSG 641
Score = 91.7 bits (226), Expect = 2e-18
Identities = 56/118 (47%), Positives = 57/118 (48%), Gaps = 17/118 (14%)
Query: 461 GGDRGGGYGGDRGGGYGGDRGGYGGDRGGGYGGDRGGYGGDRGGYGGDRGGYGGDRGGYG 520
GG RGGG GGGYG YG GGG G GG GG RG YG YG G YG
Sbjct: 515 GGSRGGG-----GGGYGSGGSSYGS--GGGSYGSGGGGGGGRGSYGSGGSSYGSGGGSYG 567
Query: 521 GDRSRGGYGGDRGGGSGYG-GDRSGGYGGDRSGGGYGGDRGGGYGGDRGGYGGKMGGR 577
GG GG YG G SGGY G GGG G G G GG G GG +GGR
Sbjct: 568 S-------GGGGGGHGSYGSGSSSGGYRGGSGGGGGGSSGGRGSGG--GSSGGSIGGR 616
Score = 90.9 bits (224), Expect = 3e-18
Identities = 51/112 (45%), Positives = 52/112 (46%), Gaps = 3/112 (2%)
Query: 465 GGGYGGDRGGGYGGDRGGYGGDRGGGYGGDRGGYGGDRGGYGGDRGGYGGDRGGYGGDRS 524
GGG G GGGYG YG GGG G GG GG RG YG YG G YG
Sbjct: 514 GGGSRGGGGGGYGSGGSSYGS--GGGSYGSGGGGGGGRGSYGSGGSSYGSGGGSYGSGGG 571
Query: 525 RGGYGGDRGGGSGYGGDRSGGYGGDRSGGGYGGDRGGGYGGDRGGYGGKMGG 576
GG+ G G GS GG R G GG G G GG GG GG G GG
Sbjct: 572 GGGH-GSYGSGSSSGGYRGGSGGGGGGSSGGRGSGGGSSGGSIGGRGSSSGG 622
Score = 87.4 bits (215), Expect = 3e-17
Identities = 70/178 (39%), Positives = 82/178 (46%), Gaps = 46/178 (25%)
Query: 334 RGGYRGRGGFQGRGGDPKSGDWVCPNPSCGNMNFARRNSCNQCNEPRPEDSRPSGGDFRG 393
R GYR GGF + S G +N+ RR + + +R SGG
Sbjct: 8 RSGYRSGGGFS--------------SGSAGIINYQRRTTSSS--------TRRSGGG--- 42
Query: 394 RGYGGERGYRGRGGRGGDRGGYGGDRSGGGYGGDRS-----SGGGYSGDRSGGGYGGDRS 448
GG G GG GG G RS GG +S + GG G GGGYGG
Sbjct: 43 ---GGRFSSCGGGGGSFGAGGGFGSRSLVNLGGSKSISISVARGGGRGSGFGGGYGGGGF 99
Query: 449 GGGYGGDRGGGYGGDRGGGYGGDRGGGYGGDRGGYGGDRGGGYGGDRGGYGGDRGGYG 506
GGG G GGG+GG GG GG GG+G GG+G GGG+GG GGYG GGYG
Sbjct: 100 GGG--GFGGGGFGG---GGIGGGGFGGFGSGGGGFG---GGGFGG--GGYG---GGYG 144
Score = 86.7 bits (213), Expect = 6e-17
Identities = 60/129 (46%), Positives = 61/129 (47%), Gaps = 17/129 (13%)
Query: 430 SGGGYSGDRSGGGYGGDRSGGGYGGDRGGGYGGDRGGGYG----GDRGGGYGGDRGGYGG 485
SGGG G GGGYG SGG G GG YG GGG G G G YG G YG
Sbjct: 513 SGGGSRGG-GGGGYG---SGGSSYGSGGGSYGSGGGGGGGRGSYGSGGSSYGSGGGSYGS 568
Query: 486 DRGGGYGGDRGGYGGDRGGYGGDRGGYGGDRGGYGGDRSRGGYGGDRGGGSGYGGDRSGG 545
GG GG G YG GG RGG GG GG G R G GG GG G G SGG
Sbjct: 569 ---GGGGGGHGSYGSGSSS-GGYRGGSGGGGGGSSGGRGSG--GGSSGGSIGGRGSSSGG 622
Query: 546 YGGDRSGGG 554
+S GG
Sbjct: 623 V---KSSGG 628
Score = 85.1 bits (209), Expect = 2e-16
Identities = 61/126 (48%), Positives = 61/126 (48%), Gaps = 10/126 (7%)
Query: 420 SGGGYGGDRSSGGGYSGDRSGGGYGGDRSGGGYGGDRGGGYGGDRGGGYGGDRGGGYGGD 479
SGGG S GGG G SGG G SGGG G GGG GG G GG G GG
Sbjct: 513 SGGG-----SRGGGGGGYGSGGSSYG--SGGGSYGSGGGGGGGRGSYGSGGSSYGSGGGS 565
Query: 480 RGGYGGDRGGGYGGDRGGYGGDRGGYGGDRGGYGGDRGGYGGDRSRGGYGGDRGGGSGYG 539
G GG G G G GG RGG GG GG G RG GG S GG G RG SG G
Sbjct: 566 YGSGGGGGGHGSYGSGSSSGGYRGGSGGGGGGSSGGRGSGGG--SSGGSIGGRGSSSG-G 622
Query: 540 GDRSGG 545
SGG
Sbjct: 623 VKSSGG 628
Score = 72.0 bits (175), Expect = 1e-12
Identities = 60/170 (35%), Positives = 64/170 (37%), Gaps = 47/170 (27%)
Query: 310 IKVSFATRRPEFMRGGGSGGGRRGRGGYRGRGGFQGRGGDPKSGDWVCPNPSCGNMNFAR 369
+ VS +T GG GG G GGY G G GG
Sbjct: 501 VSVSVSTSHTTISGGGSRGG---GGGGYGSGGSSYGSGG--------------------- 536
Query: 370 RNSCNQCNEPRPEDSRPSGGDFRGRGYGGERGYRGRGGR--GGDRGGYGGDRSGGGYG-- 425
S SGG G GG RG G GG G G YG GGG+G
Sbjct: 537 -------------GSYGSGG-----GGGGGRGSYGSGGSSYGSGGGSYGSGGGGGGHGSY 578
Query: 426 GDRSSGGGYSGDRSGGGYGGDRSGGGYGGDRGGGYGGDRGGGYGGDRGGG 475
G SS GGY G SGGG GG G G GG GG G RG GG + G
Sbjct: 579 GSGSSSGGYRGG-SGGGGGGSSGGRGSGGGSSGGSIGGRGSSSGGVKSSG 627
Score = 63.5 bits (153), Expect = 5e-10
Identities = 43/104 (41%), Positives = 44/104 (42%), Gaps = 26/104 (25%)
Query: 488 GGGYGGDRGGYGGDRGGYGGDRGGYGGDRGGYGGDRSRGGYGGDRGGGSGYGGDRSGGYG 547
GG GG GGYG YG G YG GG GG RG YG GGS YG
Sbjct: 515 GGSRGGGGGGYGSGGSSYGSGGGSYGSGGGGGGG---RGSYGS---GGSSYGS------- 561
Query: 548 GDRSGGGYGGDRGGG----------YGGDRGGYGGKMGGRNDYR 581
GG YG GGG GG RGG GG GG + R
Sbjct: 562 ---GGGSYGSGGGGGGHGSYGSGSSSGGYRGGSGGGGGGSSGGR 602
Score = 58.5 bits (140), Expect = 2e-08
Identities = 49/135 (36%), Positives = 53/135 (39%), Gaps = 26/135 (19%)
Query: 323 RGGGSGGGRRGRGGYRGRGGFQGRGGDPKSGDWVCPNPSCGNMNFARRNSCNQCNEPRPE 382
R G GGGR G G GG G GG F R+ N
Sbjct: 37 RRSGGGGGRFSSCG--GGGGSFGAGG-----------------GFGSRSLVNLGGSKSIS 77
Query: 383 DSRPSGGDFRGRGYGGERGYRGRGGRGGDRGGYGGDRSGGG------YGGDRSSGGGYSG 436
S GG RG G+GG G G GG G GG+GG GGG GG GGG+ G
Sbjct: 78 ISVARGGG-RGSGFGGGYGGGGFGGGGFGGGGFGGGGIGGGGFGGFGSGGGGFGGGGFGG 136
Query: 437 DRSGGGYGGDRSGGG 451
GGGYG GG
Sbjct: 137 GGYGGGYGPVCPPGG 151
Score = 48.9 bits (115), Expect = 1e-05
Identities = 42/116 (36%), Positives = 48/116 (41%), Gaps = 23/116 (19%)
Query: 324 GGGS----GGGRRGRGGYRGRGGFQGRGGDPKSGDWVCPNPSCGNMNFARRNSCNQCNEP 379
GGGS GGG GRG Y G G GG G + G+ ++ +S
Sbjct: 535 GGGSYGSGGGGGGGRGSYGSGGSSYGSGG----GSYGSGGGGGGHGSYGSGSS------- 583
Query: 380 RPEDSRPSGGDFRGRGYGGERGYRGRGGRGGDRGGYGGDRSGGGYGGDRSSGGGYS 435
SGG G G GG GRG GG GG G R G GG +SSGG S
Sbjct: 584 -------SGGYRGGSGGGGGGSSGGRGSGGGSSGGSIGGR-GSSSGGVKSSGGSSS 631
Score = 46.2 bits (108), Expect = 8e-05
Identities = 32/78 (41%), Positives = 34/78 (43%), Gaps = 6/78 (7%)
Query: 513 GGDRGGYGGDRSRGGYG-GDRGGGSGYGGDRSGGYGGDRSGGGYGGDRGGGYGGDRGGYG 571
GG RGG GG GYG G GSG G SGG GG G G G GG G G
Sbjct: 515 GGSRGGGGG-----GYGSGGSSYGSGGGSYGSGGGGGGGRGSYGSGGSSYGSGGGSYGSG 569
Query: 572 GKMGGRNDYRNDQRNRPY 589
G GG Y + + Y
Sbjct: 570 GGGGGHGSYGSGSSSGGY 587
Score = 42.4 bits (98), Expect = 0.001
Identities = 35/124 (28%), Positives = 42/124 (33%), Gaps = 8/124 (6%)
Query: 89 MESSGSQGGRAPSYDQPDYGQQDSYDQQSG-YDQHQGSYDEQSNYDQQHDSYSQNQQSYH 147
+ GS+GG Y SY G Y G + +Y SY SY
Sbjct: 512 ISGGGSRGGGGGGYGSGG----SSYGSGGGSYGSGGGGGGGRGSYGSGGSSYGSGGGSYG 567
Query: 148 SQRENYSHHTQDDRRDVSRYGEDNRGYGGSQGGGRGRGGYDKDGRGPMTGSSGGDRGGFK 207
S H + Y + G GG GGRG GG G G G GG K
Sbjct: 568 SGGGGGGHGSYGSGSSSGGYRGGSGGGGGGSSGGRGSGG---GSSGGSIGGRGSSSGGVK 624
Query: 208 NFGG 211
+ GG
Sbjct: 625 SSGG 628
Score = 37.0 bits (84), Expect = 0.051
Identities = 35/100 (35%), Positives = 38/100 (38%), Gaps = 11/100 (11%)
Query: 1 MSDSGSYGQSGGEQQSYSTYGNPGSQGYGQASQSYS--GYGQTTDSSYGQNYSGYSSYGQ 58
+S GS G GG YG+ GS YG SY G G SYG S Y S G
Sbjct: 512 ISGGGSRGGGGGG------YGSGGSS-YGSGGGSYGSGGGGGGGRGSYGSGGSSYGSGGG 564
Query: 59 SYSQSYGGYENQKQSSYSQQPYNNQGQQQNMESSGSQGGR 98
SY GG + S S G GS GGR
Sbjct: 565 SYGSGGGGGGHGSYGSGSSSGGYRGGSGGG--GGGSSGGR 602
Score = 34.7 bits (78), Expect = 0.25
Identities = 22/49 (44%), Positives = 26/49 (53%), Gaps = 2/49 (4%)
Query: 164 VSRYGEDNRGYGGSQGGGR-GRGGYDKDGRGPMTGSSGGDRGGFKNFGG 211
V+R G G+GG GGG G GG+ G G G GG GGF + GG
Sbjct: 80 VARGGGRGSGFGGGYGGGGFGGGGFGGGGFGG-GGIGGGGFGGFGSGGG 127
Score = 34.7 bits (78), Expect = 0.25
Identities = 22/52 (42%), Positives = 23/52 (44%), Gaps = 1/52 (1%)
Query: 167 YGEDNRGYGGSQGGGRGRGGYDKDGRGPMTGSSGGDRGGFKNFGGH-RDYGP 217
YG G GG GGG G GG G G GG GG GG+ YGP
Sbjct: 94 YGGGGFGGGGFGGGGFGGGGIGGGGFGGFGSGGGGFGGGGFGGGGYGGGYGP 145
Score = 32.0 bits (71), Expect = 1.6
Identities = 25/66 (37%), Positives = 28/66 (42%), Gaps = 5/66 (7%)
Query: 2 SDSGSYGQSGGEQQSYSTYGNPGSQG-YGQASQSYSGYGQTTDSSYGQNYSGYSSYGQSY 60
S SYG GG SY + G G G YG S S GY + G + G S G S
Sbjct: 554 SGGSSYGSGGG---SYGSGGGGGGHGSYGSGSSS-GGYRGGSGGGGGGSSGGRGSGGGSS 609
Query: 61 SQSYGG 66
S GG
Sbjct: 610 GGSIGG 615
Score = 31.2 bits (69), Expect = 2.8
Identities = 18/39 (46%), Positives = 18/39 (46%)
Query: 173 GYGGSQGGGRGRGGYDKDGRGPMTGSSGGDRGGFKNFGG 211
GYGG GG G GG G G G GG G FGG
Sbjct: 93 GYGGGGFGGGGFGGGGFGGGGIGGGGFGGFGSGGGGFGG 131
Score = 30.0 bits (66), Expect = 6.2
Identities = 24/73 (32%), Positives = 32/73 (43%), Gaps = 3/73 (4%)
Query: 2 SDSGSYGQSGGEQQSYSTYGNPGSQGYGQASQSYSGYGQTTDSSYGQNYSGYSSYGQSYS 61
S GSYG SGG + +YG+ S G + G G + G SG S G+
Sbjct: 561 SGGGSYG-SGGGGGGHGSYGSGSSSGGYRGGSGGGGGGSSGGRGSGGGSSGGSIGGR--G 617
Query: 62 QSYGGYENQKQSS 74
S GG ++ SS
Sbjct: 618 SSSGGVKSSGGSS 630
>gi|25777671 protein phosphatase 1, regulatory subunit 10 [Homo
sapiens]
Length = 940
Score = 96.3 bits (238), Expect = 7e-20
Identities = 98/265 (36%), Positives = 108/265 (40%), Gaps = 37/265 (13%)
Query: 324 GGGSGGGRRGRGGYRG----------RGG--FQGRGGDPKSGDWVCPNPSCGNMNFARRN 371
GG G G GG G RGG F GDP G + P G + R
Sbjct: 648 GGPMPGPHGGPGGPVGPRLLGPPPPPRGGDPFWDGPGDPMRGGPMRGGPGPGPGPYHRGR 707
Query: 372 SCNQCNEPRPEDSRPSGGDFRGRGYGGERGYRGRGGRGGDRGGYGGDRSGGGYGGDRSSG 431
NEP P P G GR GG GRGG GG G GG R G GG +
Sbjct: 708 GGRGGNEPPPPPP-PFRGARGGRSGGGPPN--GRGGPGGGMVGGGGHRPHEGPGGGMGNS 764
Query: 432 GGYSGDRS-GGGYG-GDRSGGGYGGDRGGGYGGDR-----GGGYGGDRGG----GYGGDR 480
G+ GGG G G R G GG GGG GG R GGG G G G GG
Sbjct: 765 SGHRPHEGPGGGMGSGHRPHEGPGGSMGGG-GGHRPHEGPGGGISGGSGHRPHEGPGGGM 823
Query: 481 GGYGGDRGG-GYGGDRGGYGGDR----GGYGGDRGGYGGDRGGYGGDRSRGGYGGDRGG- 534
G GG R G GG GG GG R G+GG G D G+ G RG + G
Sbjct: 824 GAGGGHRPHEGPGGSMGGSGGHRPHEGPGHGGPHGHRPHDVPGHRGHDHRGPPPHEHRGH 883
Query: 535 -GSGYGGDRSGGYGGDRSGGGYGGD 558
G G+GG GG+ G G +GGD
Sbjct: 884 DGPGHGG---GGHRGHDGGHSHGGD 905
Score = 82.0 bits (201), Expect = 1e-15
Identities = 88/255 (34%), Positives = 93/255 (36%), Gaps = 33/255 (12%)
Query: 333 GRGGYRGRGGFQGRGGDPKSGDWVCPNPSCGNMNFARRNSCNQCNEPRPEDSRPSGGDFR 392
G GG +G F G P G P G P P P GGD
Sbjct: 633 GPGGPKGMQHFPPGPGGPMPGPHGGPGGPVGP---------RLLGPPPP----PRGGDPF 679
Query: 393 GRGYGGE-RGYRGRGGRGGDRGGYGGDRSGGGYGGDRSSGGGYSGDRSGGGYGGDRSGGG 451
G G RG RGG G G Y R G G + G R G RSGGG
Sbjct: 680 WDGPGDPMRGGPMRGGPGPGPGPYHRGRGGRGGNEPPPPPPPFRGARGG------RSGGG 733
Query: 452 YGGDRGGGYGGDRGGGYGGDRGGGYGGDRGGYGGDRGGGYGGDRGGYGGDRGGYGGDRGG 511
RGG GG GGG G G GG G G R G GG G G
Sbjct: 734 PPNGRGGPGGGMVGGG-GHRPHEGPGGGMGNSSGHR------PHEGPGGGMGSGHRPHEG 786
Query: 512 YGGDRGGYGGDRSRGGYGGDRGGGSGY-----GGDRSGGYGGDRSGGGYGGDRGGGYGGD 566
GG GG GG R G GG GGSG+ G G GG R G GG GG GG
Sbjct: 787 PGGSMGGGGGHRPHEGPGGGISGGSGHRPHEGPGGGMGAGGGHRPHEGPGGSMGGS-GGH 845
Query: 567 RGGYGGKMGGRNDYR 581
R G GG + +R
Sbjct: 846 RPHEGPGHGGPHGHR 860
Score = 68.2 bits (165), Expect = 2e-11
Identities = 95/295 (32%), Positives = 110/295 (37%), Gaps = 48/295 (16%)
Query: 320 EFMRGGGSGGGRRGRGGYR------GRGGFQGRGGDPKSGDWVCPNPSCGNMNFARRNSC 373
E + GGSGG G GG + G G G P+ P G +N +
Sbjct: 535 ETLEPGGSGGSPDGAGGSKLPPVLANLMGSMGAGKGPQG-------PGGGGIN-VQEILT 586
Query: 374 NQCNEPRPEDSRPSGGDFRGRGYGGE-------RGYRGRG--GRGGDRGGYGGDRSGGGY 424
+ P +S PS + Y + G G G G GG GG + G
Sbjct: 587 SIMGSP---NSHPSEELLKQPDYSDKIKQMLVPHGLLGPGPIANGFPPGGPGGPK--GMQ 641
Query: 425 GGDRSSGGGYSGDRSG-GGYGGDRSGGGYGGDRGGGYGGDRGGG--YGGDRGGGYGGDRG 481
GG G G GG G R G RGG D G GG GG G G
Sbjct: 642 HFPPGPGGPMPGPHGGPGGPVGPRLLGPPPPPRGGDPFWDGPGDPMRGGPMRGGPGPGPG 701
Query: 482 GYGGDRGGGYGGD--------RGGYGGDRGGYG--GDRGGYGGDRGGYGGDRSRGGYGGD 531
Y RGG G + RG GG GG G RGG GG G GG R G GG
Sbjct: 702 PYHRGRGGRGGNEPPPPPPPFRGARGGRSGG-GPPNGRGGPGGGMVGGGGHRPHEGPGGG 760
Query: 532 RGGGSGYGGDRSGGYG---GDRSGGGYGGDRGGGYGGDR--GGYGGKMGGRNDYR 581
G SG+ G G G R G GG GGG GG R G GG + G + +R
Sbjct: 761 MGNSSGHRPHEGPGGGMGSGHRPHEGPGGSMGGG-GGHRPHEGPGGGISGGSGHR 814
Score = 56.6 bits (135), Expect = 6e-08
Identities = 55/180 (30%), Positives = 65/180 (36%), Gaps = 45/180 (25%)
Query: 318 RPEFMRGGGSGGGRRGRGGYRGRGGFQGRGGDPKSGDWVCPNPSCGNMNFARRNSCNQCN 377
RP GGG G G R + G GG G GG
Sbjct: 768 RPHEGPGGGMGSGHR---PHEGPGGSMGGGG----------------------------- 795
Query: 378 EPRPEDSRPSGGDFRGRGYGGERGYRGRGGRGGDRGGYGGDRSGGGYGGDRSSGGGYSGD 437
RP G G G G G+R G GG G GG R G GG GG+
Sbjct: 796 -----GHRPHEGP--GGGISGGSGHRPHEGPGGGMGAGGGHRPHEGPGGSMGGSGGHR-P 847
Query: 438 RSGGGYGGDRSGGGYG--GDRGGGYGGDRGGGYGGDRGGGYGGDRGGYGGDRGG-GYGGD 494
G G+GG + G RG + G + G G G+GG GG+ G GG +GGD
Sbjct: 848 HEGPGHGGPHGHRPHDVPGHRGHDHRGPPPHEHRGHDGPGHGG--GGHRGHDGGHSHGGD 905
Score = 33.1 bits (74), Expect = 0.73
Identities = 22/53 (41%), Positives = 28/53 (52%), Gaps = 7/53 (13%)
Query: 171 NRGYGGSQGGGRGRGGYDKDGRGPMTGSSG-----GDRGGFKNFGGHRDY-GP 217
+ G GGS GGG G ++ G G ++G SG G GG GGHR + GP
Sbjct: 784 HEGPGGSMGGGGGHRPHEGPG-GGISGGSGHRPHEGPGGGMGAGGGHRPHEGP 835
Score = 29.6 bits (65), Expect = 8.1
Identities = 18/46 (39%), Positives = 20/46 (43%), Gaps = 7/46 (15%)
Query: 179 GGGRGRGGYDKDGRGPMTGSSGGDR------GGFKNFGGHRDY-GP 217
GGG G G +G G G GG R GG GHR + GP
Sbjct: 774 GGGMGSGHRPHEGPGGSMGGGGGHRPHEGPGGGISGGSGHRPHEGP 819
>gi|47132620 keratin 2 [Homo sapiens]
Length = 639
Score = 95.9 bits (237), Expect = 9e-20
Identities = 64/141 (45%), Positives = 73/141 (51%), Gaps = 10/141 (7%)
Query: 407 GRGGDRGGYGGDRSGGGY--GGDRSSGGGYSGDRSGGGYGGDRSGGGYGGDRGGGYGGDR 464
GRGG GG+ G SG GG R S +S GG GG GGG+G G GG +
Sbjct: 11 GRGGGGGGFRGFSSGSAVVSGGSRRSTSSFSCLSRHGGGGGGFGGGGFGSRSLVGLGGTK 70
Query: 465 GGGYGGDRGGGYGGDRGGYGGDRGGGYGGDR---GGYGGDRGGYGGDRGGYGGDR-GGYG 520
GGG G GG+GG RGGG+GG GG G GG+GG GG+GG R GG+G
Sbjct: 71 SISISVAGGGGGFGAAGGFGG-RGGGFGGGSSFGGGSGFSGGGFGG--GGFGGGRFGGFG 127
Query: 521 GDRSRGGYGGDRG-GGSGYGG 540
G GG GG G G GY G
Sbjct: 128 GPGGVGGLGGPGGFGPGGYPG 148
Score = 87.8 bits (216), Expect = 3e-17
Identities = 55/127 (43%), Positives = 58/127 (45%), Gaps = 14/127 (11%)
Query: 421 GGGYGGDRSSGGGYSGDRSGGGYGGDRSGGGYGGDRGGGYGGDRGGGYGGDRGGGYGGDR 480
GG G SSGGGYS S G GG R G GG GGG GGGYG GGG GG
Sbjct: 519 GGSGGRGSSSGGGYSSGSSSYGSGG-RQSGSRGGSGGGG--SISGGGYGS--GGGSGGRY 573
Query: 481 GGYGGDRGGGYGGDRGGYGGDRGGYGGDRGGYGGDRGGYGGDRSRGGYGGDRGGGSGYGG 540
G GG +GG G GGYG G + G GG S GGYG GG S G
Sbjct: 574 GSGGGSKGGSISG---------GGYGSGGGKHSSGGGSRGGSSSGGGYGSGGGGSSSVKG 624
Query: 541 DRSGGYG 547
+G
Sbjct: 625 SSGEAFG 631
Score = 86.7 bits (213), Expect = 6e-17
Identities = 54/119 (45%), Positives = 58/119 (48%), Gaps = 9/119 (7%)
Query: 402 YRGRGGRGGDRGGYGGDRSGGGYGGDRSSGGGYSGDRSGGGYGGDRSGGGYGGDRGGGYG 461
+ G GGRG GG G YG SGG SG R G G GG SGGGYG GGG G
Sbjct: 518 FGGSGGRGSSSGG-GYSSGSSSYG----SGGRQSGSRGGSGGGGSISGGGYGS--GGGSG 570
Query: 462 GDRGGGYGGDRGGGYGGDRGGYGGDRGGGYGGDRGGYGGDRGGYGGDRGGYGGDRGGYG 520
G G G GG +GG G G GG + GG RGG GGYG GG +G G
Sbjct: 571 GRYGSG-GGSKGGSISGGGYGSGGGKHSSGGGSRGG-SSSGGGYGSGGGGSSSVKGSSG 627
Score = 83.6 bits (205), Expect = 5e-16
Identities = 59/129 (45%), Positives = 69/129 (53%), Gaps = 11/129 (8%)
Query: 387 SGGDFRGRGYGGERGYRGRGGRGGDRGGYGGDRSGGGYGGDRSSGGGYSGDRSGGGYGGD 446
SGG R G GG G GG+ G RS G GG +S +G GGG+G
Sbjct: 30 SGGSRRSTSSFSCLSRHGGGGGGFGGGGF-GSRSLVGLGGTKSISISVAG--GGGGFG-- 84
Query: 447 RSGGGYGGDRGGGYGGDRG-GGYGGDRGGGYGGDRGGYGGDRGGGYGGDRGGYGGDRGGY 505
+ GG+GG RGGG+GG GG G GGG+GG GG+GG R GG+GG GG GG G
Sbjct: 85 -AAGGFGG-RGGGFGGGSSFGGGSGFSGGGFGG--GGFGGGRFGGFGGP-GGVGGLGGPG 139
Query: 506 GGDRGGYGG 514
G GGY G
Sbjct: 140 GFGPGGYPG 148
Score = 81.6 bits (200), Expect = 2e-15
Identities = 55/129 (42%), Positives = 58/129 (44%), Gaps = 12/129 (9%)
Query: 448 SGGGYGGDRGGGYGGDRGGGYG-GDRGGGYGGDRGGYGGDRGGGYGGDRGGYGGDRGGYG 506
S +GG GG G GGGY G G GG + G G GGG GGYG G
Sbjct: 514 SKAAFGGS--GGRGSSSGGGYSSGSSSYGSGGRQSGSRGGSGGGGSISGGGYGSG----G 567
Query: 507 GDRGGYGGDRGGYGGDRSRGGYGGDRGGGSGYGGDRSGGYGGDRSGGGYGGDRGGGYGGD 566
G G YG G GG S GGYG G S GG R GG SGGGYG GGG
Sbjct: 568 GSGGRYGSGGGSKGGSISGGGYGSGGGKHSSGGGSR----GGSSSGGGYGSG-GGGSSSV 622
Query: 567 RGGYGGKMG 575
+G G G
Sbjct: 623 KGSSGEAFG 631
Score = 79.0 bits (193), Expect = 1e-14
Identities = 68/168 (40%), Positives = 76/168 (45%), Gaps = 30/168 (17%)
Query: 332 RGRGGYRGRGGFQGRGGDPKSGDWVCPNPSCGNMNFARRNSCNQCNEPRPEDSRPSGGDF 391
RGRGG G GGF+G SG V S R S C GG F
Sbjct: 10 RGRGG--GGGGFRGFS----SGSAVVSGGS------RRSTSSFSCLSRHGG----GGGGF 53
Query: 392 RGRGYGGERGYRGRGGRGGDRGGYGGDRSGGGYGGDRSSGGGYSGDRSGGGYGGDRSGGG 451
G G+G R G GG G GGG+G GG+ G GGG+GG S GG
Sbjct: 54 GGGGFGS-RSLVGLGGTKSISISVAG--GGGGFGA----AGGFGG--RGGGFGGGSSFGG 104
Query: 452 YGGDRGGGYGGDRGGGYGGDRGGGYGGDR--GGYGGDRGGGYGGDRGG 497
G GGG+G GGG+GG R GG+GG GG GG G G GG GG
Sbjct: 105 GSGFSGGGFG---GGGFGGGRFGGFGGPGGVGGLGGPGGFGPGGYPGG 149
Score = 78.6 bits (192), Expect = 2e-14
Identities = 59/143 (41%), Positives = 68/143 (47%), Gaps = 33/143 (23%)
Query: 392 RGRGYGGERGY----------------------RGRGGRGGDRGGYGGDRSGGGYGGDRS 429
RG G GG RG+ R GG GG GG G RS G GG +S
Sbjct: 12 RGGGGGGFRGFSSGSAVVSGGSRRSTSSFSCLSRHGGGGGGFGGGGFGSRSLVGLGGTKS 71
Query: 430 SG----GGYSGDRSGGGYGGDRSGGGYGGDRGGGYGGDRGGGYGGDRGGGYGGDR-GGYG 484
GG G + GG+GG GGG+GG G +GG G GG GGG+GG R GG+G
Sbjct: 72 ISISVAGGGGGFGAAGGFGG--RGGGFGG--GSSFGGGSGFSGGGFGGGGFGGGRFGGFG 127
Query: 485 GDRGGGYGGDRGGYGGDRGGYGG 507
G G G G GG+G GGY G
Sbjct: 128 GPGGVGGLGGPGGFG--PGGYPG 148
Score = 75.9 bits (185), Expect = 1e-13
Identities = 49/104 (47%), Positives = 50/104 (48%), Gaps = 8/104 (7%)
Query: 389 GDFRGRGYGGERGYRGRGGR-GGDRGGYGGDRS--GGGYGGDRSSGGGYSGDRSGGGYGG 445
G G GY G GGR G RGG GG S GGGYG SGG Y GG GG
Sbjct: 525 GSSSGGGYSSGSSSYGSGGRQSGSRGGSGGGGSISGGGYGSGGGSGGRYGS--GGGSKGG 582
Query: 446 DRSGGGYGGDRGGGYGGDRGGGYGG-DRGGGYGGDRGGYGGDRG 488
SGGGYG GGG GG GG GGGYG GG +G
Sbjct: 583 SISGGGYGS--GGGKHSSGGGSRGGSSSGGGYGSGGGGSSSVKG 624
Score = 73.9 bits (180), Expect = 4e-13
Identities = 52/123 (42%), Positives = 57/123 (46%), Gaps = 9/123 (7%)
Query: 384 SRPSGGDFRGRGYGGERGYRGRGGRGGDRGGYGGDRSGGGYGGDRSSGGGYSGDRSGGGY 443
S+ + G GRG GY G G G R G G GG SGGGY SGGG
Sbjct: 514 SKAAFGGSGGRGSSSGGGYSSGSSSYGSGGRQSGSRGGSG-GGGSISGGGYG---SGGGS 569
Query: 444 GGDRSGGGYGGDRGGGYGGDRGGGYGGDRGGGYGGDRGGYGGDRGGGYGGDRGGYGGDRG 503
GG R G G GG +GG G G G GG + GG RG G GGGYG GG +G
Sbjct: 570 GG-RYGSG-GGSKGGSISGG-GYGSGGGKHSSGGGSRG--GSSSGGGYGSGGGGSSSVKG 624
Query: 504 GYG 506
G
Sbjct: 625 SSG 627
Score = 73.6 bits (179), Expect = 5e-13
Identities = 48/114 (42%), Positives = 50/114 (43%), Gaps = 19/114 (16%)
Query: 478 GDRGGYGGDRGGGYGGDRGGYGGDRGGYGGDRGGYGGDRGGYGGDRSRGGYGGDRGGGSG 537
G GG G GGGY YG G G RGG GG GG S GGYG G G
Sbjct: 519 GGSGGRGSSSGGGYSSGSSSYGSG-GRQSGSRGGSGG-----GGSISGGGYGSGGGSGGR 572
Query: 538 YGGDRSGGYGGDRSGGGY----------GGDRGGGYGGDRGGYGGKMGGRNDYR 581
YG G GG SGGGY GG RGG G GGYG GG + +
Sbjct: 573 YGSG-GGSKGGSISGGGYGSGGGKHSSGGGSRGGSSSG--GGYGSGGGGSSSVK 623
Score = 64.7 bits (156), Expect = 2e-10
Identities = 52/137 (37%), Positives = 57/137 (41%), Gaps = 26/137 (18%)
Query: 335 GGYRGRGGFQGRGGDPKSGDWVCPNPSCGNMNFARRNSCNQCNEPRPEDSRPSGGDFRGR 394
GG GRG G G S + S G + +R S GG G
Sbjct: 519 GGSGGRGSSSGGGYSSGSSSY----GSGGRQSGSRGGS-------------GGGGSISGG 561
Query: 395 GYGGERGYRGRGGRGGDRGGYGGDRSGGGYGGDRSSGGGYSGDRSGGGYGGDRSGGGYGG 454
GYG G GR G GG G GG SGGGYG S GG +S GG GG SGGGYG
Sbjct: 562 GYGSGGGSGGRYGSGG--GSKGGSISGGGYG---SGGGKHSS--GGGSRGGSSSGGGYGS 614
Query: 455 DRGGGYG--GDRGGGYG 469
GG G G +G
Sbjct: 615 GGGGSSSVKGSSGEAFG 631
Score = 52.8 bits (125), Expect = 9e-07
Identities = 31/75 (41%), Positives = 34/75 (45%), Gaps = 7/75 (9%)
Query: 502 RGGYGGDRGGYGGDRGGYGGDRSRGGYGGDRGGGSGYGGDRSGGYGGDRSGGGYGGDRGG 561
+ +GG G GGY S G GG + G G G GG SGGGYG GG
Sbjct: 515 KAAFGGSGGRGSSSGGGYSSGSSSYGSGGRQSGSRG-----GSGGGGSISGGGYGS--GG 567
Query: 562 GYGGDRGGYGGKMGG 576
G GG G GG GG
Sbjct: 568 GSGGRYGSGGGSKGG 582
Score = 47.8 bits (112), Expect = 3e-05
Identities = 38/120 (31%), Positives = 39/120 (32%), Gaps = 41/120 (34%)
Query: 323 RGGGSGGGRRGRGGYRGRGGFQGRGGDPKSGDWVCPNPSCGNMNFARRNSCNQCNEPRPE 382
RGG GGG GGY GG GR G
Sbjct: 549 RGGSGGGGSISGGGYGSGGGSGGRYG---------------------------------S 575
Query: 383 DSRPSGGDFRGRGYGGERGYRGRGGRGGDRGGYGGDRSGGGYGGDRSSGGGYSGDRSGGG 442
GG G GYG G GG G GG SGGGYG S GGG S + G
Sbjct: 576 GGGSKGGSISGGGYGSGGGKHSSGG-----GSRGGSSSGGGYG---SGGGGSSSVKGSSG 627
Score = 44.7 bits (104), Expect = 2e-04
Identities = 39/103 (37%), Positives = 42/103 (40%), Gaps = 33/103 (32%)
Query: 326 GSGGGRRGRGGYRGRGGFQGRGGDPKSGDWVCPNPSCGNMNFARRNSCNQCNEPRPEDSR 385
G GGG GG+ GRGG G GG G G F
Sbjct: 78 GGGGGFGAAGGFGGRGG--GFGGGSSFG---------GGSGF------------------ 108
Query: 386 PSGGDFRGRGYGGER--GYRGRGGRGGDRGGYGGDRSGGGYGG 426
SGG F G G+GG R G+ G GG GG GG GG GG GG
Sbjct: 109 -SGGGFGGGGFGGGRFGGFGGPGGVGG-LGGPGGFGPGGYPGG 149
Score = 44.7 bits (104), Expect = 2e-04
Identities = 27/59 (45%), Positives = 29/59 (49%), Gaps = 5/59 (8%)
Query: 524 SRGGYGGDRGGGSGYGGDRSGGYGGDRSGGGYGGDRGGGYGG---DRGGY--GGKMGGR 577
S+ +GG G GS GG S G SGG G RGG GG GGY GG GGR
Sbjct: 514 SKAAFGGSGGRGSSSGGGYSSGSSSYGSGGRQSGSRGGSGGGGSISGGGYGSGGGSGGR 572
Score = 34.3 bits (77), Expect = 0.33
Identities = 28/84 (33%), Positives = 32/84 (38%), Gaps = 13/84 (15%)
Query: 168 GEDNRGYGGSQGGGRG---------RGGYDK-DGRGPMTGSSGGDRGGFKNFGGHRDYGP 217
G + G GG Q G RG GGY G G GS GG +GG + GG YG
Sbjct: 535 GSSSYGSGGRQSGSRGGSGGGGSISGGGYGSGGGSGGRYGSGGGSKGGSISGGG---YGS 591
Query: 218 RTDADSESDNSDNNTIFVQGLGEG 241
S S + G G G
Sbjct: 592 GGGKHSSGGGSRGGSSSGGGYGSG 615
Score = 33.9 bits (76), Expect = 0.43
Identities = 21/51 (41%), Positives = 25/51 (49%), Gaps = 6/51 (11%)
Query: 166 RYGEDNRGYGGSQGGGRGRGGYDKDGRGPMTGSSGGDRGGFKNFGGHRDYG 216
RYG GGS+GG GGY G +G GG RGG + GG+ G
Sbjct: 572 RYGSG----GGSKGGSISGGGYGSGGGKHSSG--GGSRGGSSSGGGYGSGG 616
Score = 32.7 bits (73), Expect = 0.96
Identities = 29/103 (28%), Positives = 42/103 (40%), Gaps = 15/103 (14%)
Query: 1 MSDSGSYGQSGGEQQSYSTYGNPGSQGYGQASQSYSGYGQTTDSSYGQ------NYSGYS 54
++ ++G SGG G+ GY S SY G+ + S G + GY
Sbjct: 512 VASKAAFGGSGGR-------GSSSGGGYSSGSSSYGSGGRQSGSRGGSGGGGSISGGGYG 564
Query: 55 SYGQSYSQSYGGYENQKQSSYSQQPYNNQGQQQNMESSGSQGG 97
S G S + YG K S S Y + G + + GS+GG
Sbjct: 565 SGGGSGGR-YGSGGGSKGGSISGGGYGSGGGKHS-SGGGSRGG 605
Score = 32.3 bits (72), Expect = 1.3
Identities = 19/61 (31%), Positives = 27/61 (44%)
Query: 5 GSYGQSGGEQQSYSTYGNPGSQGYGQASQSYSGYGQTTDSSYGQNYSGYSSYGQSYSQSY 64
G YG GG + + G GS G +S S G ++ YG G SS S +++
Sbjct: 571 GRYGSGGGSKGGSISGGGYGSGGGKHSSGGGSRGGSSSGGGYGSGGGGSSSVKGSSGEAF 630
Query: 65 G 65
G
Sbjct: 631 G 631
Score = 31.6 bits (70), Expect = 2.1
Identities = 25/74 (33%), Positives = 30/74 (40%), Gaps = 4/74 (5%)
Query: 154 SHHTQDDRRDVSRYGEDNRGY--GGSQGGGRGRGGYDKDGRGPMTGSSGGDRGGFKNFGG 211
S + R+ SR G G GG G G G GG G G GS G GG+ + GG
Sbjct: 537 SSYGSGGRQSGSRGGSGGGGSISGGGYGSGGGSGGRYGSGGGSKGGSISG--GGYGSGGG 594
Query: 212 HRDYGPRTDADSES 225
G + S S
Sbjct: 595 KHSSGGGSRGGSSS 608
Score = 31.2 bits (69), Expect = 2.8
Identities = 22/70 (31%), Positives = 26/70 (37%), Gaps = 1/70 (1%)
Query: 173 GYGGSQGGGRGRGGYDKDGRGPMTGSSGGDRGGFK-NFGGHRDYGPRTDADSESDNSDNN 231
G G S GGG G G +GS GG GG + GG+ G S
Sbjct: 523 GRGSSSGGGYSSGSSSYGSGGRQSGSRGGSGGGGSISGGGYGSGGGSGGRYGSGGGSKGG 582
Query: 232 TIFVQGLGEG 241
+I G G G
Sbjct: 583 SISGGGYGSG 592
Score = 30.8 bits (68), Expect = 3.6
Identities = 26/67 (38%), Positives = 29/67 (43%), Gaps = 3/67 (4%)
Query: 4 SGSYGQSGGEQQ-SYSTYGNPGSQGYGQASQSYSGYGQTTDSSYGQNYSGYSSYGQSY-- 60
SGS G SGG S YG+ G G S S G + YG +SS G S
Sbjct: 546 SGSRGGSGGGGSISGGGYGSGGGSGGRYGSGGGSKGGSISGGGYGSGGGKHSSGGGSRGG 605
Query: 61 SQSYGGY 67
S S GGY
Sbjct: 606 SSSGGGY 612
Score = 29.6 bits (65), Expect = 8.1
Identities = 15/25 (60%), Positives = 16/25 (64%), Gaps = 2/25 (8%)
Query: 324 GGGSGGGRRGRGGYRGRGGFQGRGG 348
GGG GGGR G G+ G GG G GG
Sbjct: 115 GGGFGGGRFG--GFGGPGGVGGLGG 137
Score = 29.6 bits (65), Expect = 8.1
Identities = 36/100 (36%), Positives = 43/100 (43%), Gaps = 12/100 (12%)
Query: 2 SDSGSYGQSGGEQQSYSTYGNPGSQGYGQASQSYSGYGQTTDSSYGQNYSGYSSYGQSYS 61
S S SYG SGG Q G+ G G G S S GYG + S G+ SG S G S S
Sbjct: 534 SGSSSYG-SGGRQS-----GSRGGSG-GGGSISGGGYG-SGGGSGGRYGSGGGSKGGSIS 585
Query: 62 QSYGGYENQKQSSYSQQPYNNQGQQQNMESSGSQGGRAPS 101
G K SS ++G + GS GG + S
Sbjct: 586 GGGYGSGGGKHSSGG----GSRGGSSSGGGYGSGGGGSSS 621
>gi|58761498 heterogeneous nuclear ribonucleoprotein A1-like [Homo
sapiens]
Length = 320
Score = 94.0 bits (232), Expect = 3e-19
Identities = 86/286 (30%), Positives = 119/286 (41%), Gaps = 67/286 (23%)
Query: 218 RTDADSESDNSDNNTIFVQGLGEGVSTDQVGEFFKQIGIIKTNKKTGKPMINLYTDKDTG 277
R D+ + IFV G+ E + ++F+Q G I+ +I + TD+ +G
Sbjct: 92 REDSQRPGAHLTVKKIFVGGIKEDTEEHHLRDYFEQYGKIE--------VIEIMTDRGSG 143
Query: 278 KPKGEATVSFDDPPSAKAAIDWFDGKEFH---GNIIKVSFATRRPEFMRGGGSGGGRRGR 334
K +G A V+FDD S +D +++H G+ +V A + E S GRRG
Sbjct: 144 KKRGFAFVTFDDHDS----VDKIVIQKYHTVKGHNCEVRKALPKQEMASASSSQRGRRGS 199
Query: 335 GGYRGRGGFQGRGGDPKSGDWVCPNPSCGNMNFARRNSCNQCNEPRPEDSRPSGGDFRGR 394
G + GG +G G GN NF R GG+F GR
Sbjct: 200 GNF---GGGRGDGFG-------------GNDNFGR------------------GGNFSGR 225
Query: 395 -GYGGERGYRGRGGRGGDRGGYGGDRSGGGYGGDRSSGGGYSGDRSGGGYGGDRSGGGYG 453
G+GG G G GG G G+G D S G GG + G Y+ S +G
Sbjct: 226 GGFGGSCGGGGYGGSGDGYNGFGNDGSNFGGGGSYNDFGNYNNQSS-----------NFG 274
Query: 454 GDRGGGYGGDRGGGYGGDRGGGYGG---DRGGYG-GDRGGGYGGDR 495
+GG +GG G YGG GG Y ++GGYG YG R
Sbjct: 275 PMKGGNFGGRSSGPYGG--GGQYFAKPQNQGGYGVSSSSSSYGSGR 318
Score = 86.3 bits (212), Expect = 7e-17
Identities = 54/130 (41%), Positives = 67/130 (51%), Gaps = 21/130 (16%)
Query: 445 GDRSGGGYGGDRGGGYGGDRGGGYGGDRGGGYGGDRGGYGGDRGGGYGGDRGGYGGDRGG 504
G R G +GG RG G+GG+ G RGG + G RGG+GG GGG GYGG G
Sbjct: 195 GRRGSGNFGGGRGDGFGGNDNFG----RGGNFSG-RGGFGGSCGGG------GYGGSGDG 243
Query: 505 YGGDRGGYGGDRGGYGGDRSRGGYGGDRGGGSGYGGDRSGGYGGDRSGGGYGGDRGGGYG 564
Y G +G D +GG S +G S +G + G +GG RS G YGG GG Y
Sbjct: 244 YNG----FGNDGSNFGGGGSYNDFGNYNNQSSNFGPMKGGNFGG-RSSGPYGG--GGQYF 296
Query: 565 G---DRGGYG 571
++GGYG
Sbjct: 297 AKPQNQGGYG 306
Score = 85.1 bits (209), Expect = 2e-16
Identities = 56/137 (40%), Positives = 65/137 (47%), Gaps = 12/137 (8%)
Query: 429 SSGGGYSGDRSGGGYGGDRSGGGYGGD----RGGGYGGDRGGGYGGDRGGGYGGDRGGYG 484
S+ G R G +GG R G G+GG+ RGG + G RGG G GGGYGG GY
Sbjct: 188 SASSSQRGRRGSGNFGGGR-GDGFGGNDNFGRGGNFSG-RGGFGGSCGGGGYGGSGDGYN 245
Query: 485 --GDRGGGYGGDRGGYGGDRGGYGGDRGGYGGDRGGYGGDRSRGGYGGDRGGGSGYGGDR 542
G+ G +GG GG D G Y +G +GG G RS G YGG GG
Sbjct: 246 GFGNDGSNFGG--GGSYNDFGNYNNQSSNFGPMKGGNFGGRSSGPYGG--GGQYFAKPQN 301
Query: 543 SGGYGGDRSGGGYGGDR 559
GGYG S YG R
Sbjct: 302 QGGYGVSSSSSSYGSGR 318
Score = 85.1 bits (209), Expect = 2e-16
Identities = 54/135 (40%), Positives = 64/135 (47%), Gaps = 10/135 (7%)
Query: 399 ERGYRGRGGRGGDRGGYGGDRSGGGYGGDRSSGGGYSGDRSGGGYGGDRSGGGYGGDRGG 458
+RG RG G GG RG G G GG+ S GG+ G GGGYGG SG GY G G
Sbjct: 193 QRGRRGSGNFGGGRGDGFGGNDNFGRGGNFSGRGGFGGSCGGGGYGG--SGDGYNG--FG 248
Query: 459 GYGGDRGGGYGGDRGGGYGGDRGGYGGDRGGGYGG-DRGGYGGDRGGYGGDRGGYGGDRG 517
G + GGG + G Y +G +GG +GG G YGG GG ++G
Sbjct: 249 NDGSNFGGGGSYNDFGNYNNQSSNFGPMKGGNFGGRSSGPYGG-----GGQYFAKPQNQG 303
Query: 518 GYGGDRSRGGYGGDR 532
GYG S YG R
Sbjct: 304 GYGVSSSSSSYGSGR 318
Score = 69.7 bits (169), Expect = 7e-12
Identities = 49/113 (43%), Positives = 59/113 (52%), Gaps = 18/113 (15%)
Query: 462 GDRGGG-YGGDRGGGYGGDRGGYGGDRGGGYGGDRGGYGGDRGGYGGDRGGYGGDRGGYG 520
G RG G +GG RG G+GG+ +G RGG + G RGG+GG GG GGYGG GY
Sbjct: 195 GRRGSGNFGGGRGDGFGGN-DNFG--RGGNFSG-RGGFGGSCGG-----GGYGGSGDGYN 245
Query: 521 GDRSRGGYGGDRGGGSGYGGDRSGGYGGDRSGGGYGGDRGGGYGG-DRGGYGG 572
G G G + GGG Y G Y S +G +GG +GG G YGG
Sbjct: 246 GF---GNDGSNFGGGGSYND--FGNYNNQSSN--FGPMKGGNFGGRSSGPYGG 291
Score = 53.5 bits (127), Expect = 5e-07
Identities = 31/67 (46%), Positives = 38/67 (56%), Gaps = 9/67 (13%)
Query: 521 GDRSRGGYGGDRGGGSGYGGDRSGGYGGDRSG-GGYGGDRGGGYGGDRGGYGGKMGGRND 579
G R G +GG RG G+GG+ + G GG+ SG GG+GG GGG GYGG G N
Sbjct: 195 GRRGSGNFGGGRG--DGFGGNDNFGRGGNFSGRGGFGGSCGGG------GYGGSGDGYNG 246
Query: 580 YRNDQRN 586
+ ND N
Sbjct: 247 FGNDGSN 253
Score = 52.8 bits (125), Expect = 9e-07
Identities = 38/83 (45%), Positives = 45/83 (54%), Gaps = 20/83 (24%)
Query: 503 GGYGGDRG-GYGG-DRGGYGGDRS-RGGYGGDRGGGSGYGGDRSGGYGGDRSGGGYGGDR 559
G +GG RG G+GG D G GG+ S RGG+GG GGG GYGG SG GY
Sbjct: 200 GNFGGGRGDGFGGNDNFGRGGNFSGRGGFGGSCGGG---------GYGG--SGDGY---- 244
Query: 560 GGGYGGDRGGYGGKMGGRNDYRN 582
G+G D +GG G ND+ N
Sbjct: 245 -NGFGNDGSNFGGG-GSYNDFGN 265
Score = 38.5 bits (88), Expect = 0.017
Identities = 30/113 (26%), Positives = 41/113 (36%), Gaps = 22/113 (19%)
Query: 6 SYGQSGGEQQSYSTYGNPGSQGYGQASQSYSGYGQTTDSSYGQNYSGYSSYGQSYSQSYG 65
++G+ G G+ G GYG + Y+G+G G N+ G SY +G
Sbjct: 215 NFGRGGNFSGRGGFGGSCGGGGYGGSGDGYNGFGND-----GSNFGGGGSYND-----FG 264
Query: 66 GYENQKQS----------SYSQQPYNNQGQQQNMESSGSQGGRAPSYDQPDYG 108
Y NQ + S PY GQ +QGG S YG
Sbjct: 265 NYNNQSSNFGPMKGGNFGGRSSGPYGGGGQY--FAKPQNQGGYGVSSSSSSYG 315
Score = 36.6 bits (83), Expect = 0.066
Identities = 18/45 (40%), Positives = 22/45 (48%), Gaps = 11/45 (24%)
Query: 543 SGGYGGDRSGGGYGGDRGGGYGGD-----------RGGYGGKMGG 576
S G R G +GG RG G+GG+ RGG+GG GG
Sbjct: 190 SSSQRGRRGSGNFGGGRGDGFGGNDNFGRGGNFSGRGGFGGSCGG 234
Score = 34.7 bits (78), Expect = 0.25
Identities = 39/124 (31%), Positives = 52/124 (41%), Gaps = 16/124 (12%)
Query: 136 HDSYSQNQ-QSYHSQR-ENYSHHTQDDRRDVSRYGEDNRGYGGSQ--GGGRGRG--GYDK 189
HDS + Q YH+ + N +++++ RG GS GGGRG G G D
Sbjct: 156 HDSVDKIVIQKYHTVKGHNCEVRKALPKQEMASASSSQRGRRGSGNFGGGRGDGFGGNDN 215
Query: 190 DGRGPMTGSSGGDRGGFKNFGGHRDYGPRTDADSESDNSDNNTIFVQGLGEGVSTDQVGE 249
GRG G+ G RGGF G YG D + N +N G G S + G
Sbjct: 216 FGRG---GNFSG-RGGFGGSCGGGGYGGSGDGYNGFGNDGSN------FGGGGSYNDFGN 265
Query: 250 FFKQ 253
+ Q
Sbjct: 266 YNNQ 269
Score = 33.1 bits (74), Expect = 0.73
Identities = 23/64 (35%), Positives = 29/64 (45%), Gaps = 7/64 (10%)
Query: 168 GEDNRGYGGSQGGGRGRGGYDKDGRGPMTGSSGGDRGGF----KNFGGHRDYGPRTDADS 223
G DN G GG+ GRGG+ G G SG GF NFGG Y + ++
Sbjct: 212 GNDNFGRGGNF---SGRGGFGGSCGGGGYGGSGDGYNGFGNDGSNFGGGGSYNDFGNYNN 268
Query: 224 ESDN 227
+S N
Sbjct: 269 QSSN 272
Database: hs.faa
Posted date: Aug 4, 2009 4:42 PM
Number of letters in database: 18,247,518
Number of sequences in database: 37,866
Lambda K H
0.309 0.140 0.438
Gapped
Lambda K H
0.267 0.0410 0.140
Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Hits to DB: 31,253,403
Number of Sequences: 37866
Number of extensions: 2285643
Number of successful extensions: 68174
Number of sequences better than 10.0: 30
Number of HSP's better than 10.0 without gapping: 559
Number of HSP's successfully gapped in prelim test: 505
Number of HSP's that attempted gapping in prelim test: 14151
Number of HSP's gapped (non-prelim): 19881
length of query: 589
length of database: 18,247,518
effective HSP length: 108
effective length of query: 481
effective length of database: 14,157,990
effective search space: 6809993190
effective search space used: 6809993190
T: 11
A: 40
X1: 16 ( 7.1 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 42 (21.6 bits)
S2: 65 (29.6 bits)
Search results were obtained with NCBI BLAST and RefSeq entries.
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Guide to the Human Genome
Copyright © 2010 by Stewart Scherer. All rights reserved.