Guide to the Human Genome
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Search of human proteins with 4507125

BLASTP 2.2.11 [Jun-05-2005]


Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer, 
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), 
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs",  Nucleic Acids Res. 25:3389-3402.

Query= gi|4507125 small nuclear ribonucleoprotein polypeptide B/B'
isoform B [Homo sapiens]
         (231 letters)

Database: hs.faa 
           37,866 sequences; 18,247,518 total letters

Searching..................................................done

                                                                 Score    E
Sequences producing significant alignments:                      (bits) Value

gi|4507125 small nuclear ribonucleoprotein polypeptide B/B' isof...   484   e-137
gi|38150007 small nuclear ribonucleoprotein polypeptide B/B' iso...   481   e-136
gi|13027650 small nuclear ribonucleoprotein polypeptide N [Homo ...   454   e-128
gi|13027648 small nuclear ribonucleoprotein polypeptide N [Homo ...   454   e-128
gi|13027646 small nuclear ribonucleoprotein polypeptide N [Homo ...   454   e-128
gi|13027644 small nuclear ribonucleoprotein polypeptide N [Homo ...   454   e-128
gi|4507135 small nuclear ribonucleoprotein polypeptide N [Homo s...   454   e-128
gi|169216044 PREDICTED: similar to hCG2041320 [Homo sapiens]          234   5e-62
gi|169215838 PREDICTED: similar to hCG2041320 [Homo sapiens]          234   5e-62
gi|169215637 PREDICTED: similar to hCG2041320 [Homo sapiens]          234   5e-62
gi|5032069 splicing factor 3b, subunit 4 [Homo sapiens]                75   4e-14
gi|40805823 collagen, type XXII, alpha 1 [Homo sapiens]                66   2e-11
gi|18641360 collectin sub-family member 12 [Homo sapiens]              66   3e-11
gi|39930517 sterile alpha motif domain containing 1 [Homo sapiens]     65   4e-11
gi|111118976 collagen, type II, alpha 1 isoform 1 precursor [Hom...    65   5e-11
gi|111118974 collagen, type II, alpha 1 isoform 2 precursor [Hom...    65   5e-11
gi|89276751 alpha 1 type V collagen preproprotein [Homo sapiens]       65   5e-11
gi|4826998 splicing factor proline/glutamine rich (polypyrimidin...    65   6e-11
gi|160707881 formin 2 [Homo sapiens]                                   64   8e-11
gi|110349772 alpha 1 type I collagen preproprotein [Homo sapiens]      64   1e-10
gi|4557317 annexin A11 [Homo sapiens]                                  64   1e-10
gi|22165433 annexin A11 [Homo sapiens]                                 64   1e-10
gi|22165431 annexin A11 [Homo sapiens]                                 64   1e-10
gi|7706501 WW domain binding protein 11 [Homo sapiens]                 63   2e-10
gi|209571537 proline-rich protein BstNI subfamily 2 [Homo sapiens]     63   2e-10
gi|157168329 formin 1 [Homo sapiens]                                   62   4e-10
gi|42544123 splicing factor 1 isoform 3 [Homo sapiens]                 62   5e-10
gi|42544125 splicing factor 1 isoform 2 [Homo sapiens]                 62   5e-10
gi|42544130 splicing factor 1 isoform 1 [Homo sapiens]                 62   5e-10
gi|126352608 elastin isoform e precursor [Homo sapiens]                61   7e-10

>gi|4507125 small nuclear ribonucleoprotein polypeptide B/B' isoform
           B [Homo sapiens]
          Length = 231

 Score =  484 bits (1245), Expect = e-137
 Identities = 231/231 (100%), Positives = 231/231 (100%)

Query: 1   MTVGKSSKMLQHIDYRMRCILQDGRIFIGTFKAFDKHMNLILCDCDEFRKIKPKNSKQAE 60
           MTVGKSSKMLQHIDYRMRCILQDGRIFIGTFKAFDKHMNLILCDCDEFRKIKPKNSKQAE
Sbjct: 1   MTVGKSSKMLQHIDYRMRCILQDGRIFIGTFKAFDKHMNLILCDCDEFRKIKPKNSKQAE 60

Query: 61  REEKRVLGLVLLRGENLVSMTVEGPPPKDTGIARVPLAGAAGGPGIGRAAGRGIPAGVPM 120
           REEKRVLGLVLLRGENLVSMTVEGPPPKDTGIARVPLAGAAGGPGIGRAAGRGIPAGVPM
Sbjct: 61  REEKRVLGLVLLRGENLVSMTVEGPPPKDTGIARVPLAGAAGGPGIGRAAGRGIPAGVPM 120

Query: 121 PQAPAGLAGPVRGVGGPSQQVMTPQGRGTVAAAAAAATASIAGAPTQYPPGRGGPPPPMG 180
           PQAPAGLAGPVRGVGGPSQQVMTPQGRGTVAAAAAAATASIAGAPTQYPPGRGGPPPPMG
Sbjct: 121 PQAPAGLAGPVRGVGGPSQQVMTPQGRGTVAAAAAAATASIAGAPTQYPPGRGGPPPPMG 180

Query: 181 RGAPPPGMMGPPPGMRPPMGPPMGIPPGRGTPMGMPPPGMRPPPPGMRGLL 231
           RGAPPPGMMGPPPGMRPPMGPPMGIPPGRGTPMGMPPPGMRPPPPGMRGLL
Sbjct: 181 RGAPPPGMMGPPPGMRPPMGPPMGIPPGRGTPMGMPPPGMRPPPPGMRGLL 231


>gi|38150007 small nuclear ribonucleoprotein polypeptide B/B'
           isoform B' [Homo sapiens]
          Length = 240

 Score =  481 bits (1237), Expect = e-136
 Identities = 229/229 (100%), Positives = 229/229 (100%)

Query: 1   MTVGKSSKMLQHIDYRMRCILQDGRIFIGTFKAFDKHMNLILCDCDEFRKIKPKNSKQAE 60
           MTVGKSSKMLQHIDYRMRCILQDGRIFIGTFKAFDKHMNLILCDCDEFRKIKPKNSKQAE
Sbjct: 1   MTVGKSSKMLQHIDYRMRCILQDGRIFIGTFKAFDKHMNLILCDCDEFRKIKPKNSKQAE 60

Query: 61  REEKRVLGLVLLRGENLVSMTVEGPPPKDTGIARVPLAGAAGGPGIGRAAGRGIPAGVPM 120
           REEKRVLGLVLLRGENLVSMTVEGPPPKDTGIARVPLAGAAGGPGIGRAAGRGIPAGVPM
Sbjct: 61  REEKRVLGLVLLRGENLVSMTVEGPPPKDTGIARVPLAGAAGGPGIGRAAGRGIPAGVPM 120

Query: 121 PQAPAGLAGPVRGVGGPSQQVMTPQGRGTVAAAAAAATASIAGAPTQYPPGRGGPPPPMG 180
           PQAPAGLAGPVRGVGGPSQQVMTPQGRGTVAAAAAAATASIAGAPTQYPPGRGGPPPPMG
Sbjct: 121 PQAPAGLAGPVRGVGGPSQQVMTPQGRGTVAAAAAAATASIAGAPTQYPPGRGGPPPPMG 180

Query: 181 RGAPPPGMMGPPPGMRPPMGPPMGIPPGRGTPMGMPPPGMRPPPPGMRG 229
           RGAPPPGMMGPPPGMRPPMGPPMGIPPGRGTPMGMPPPGMRPPPPGMRG
Sbjct: 181 RGAPPPGMMGPPPGMRPPMGPPMGIPPGRGTPMGMPPPGMRPPPPGMRG 229


>gi|13027650 small nuclear ribonucleoprotein polypeptide N [Homo
           sapiens]
          Length = 240

 Score =  454 bits (1167), Expect = e-128
 Identities = 212/229 (92%), Positives = 222/229 (96%)

Query: 1   MTVGKSSKMLQHIDYRMRCILQDGRIFIGTFKAFDKHMNLILCDCDEFRKIKPKNSKQAE 60
           MTVGKSSKMLQHIDYRMRCILQDGRIFIGTFKAFDKHMNLILCDCDEFRKIKPKN+KQ E
Sbjct: 1   MTVGKSSKMLQHIDYRMRCILQDGRIFIGTFKAFDKHMNLILCDCDEFRKIKPKNAKQPE 60

Query: 61  REEKRVLGLVLLRGENLVSMTVEGPPPKDTGIARVPLAGAAGGPGIGRAAGRGIPAGVPM 120
           REEKRVLGLVLLRGENLVSMTVEGPPPKDTGIARVPLAGAAGGPG+GRAAGRG+PAGVP+
Sbjct: 61  REEKRVLGLVLLRGENLVSMTVEGPPPKDTGIARVPLAGAAGGPGVGRAAGRGVPAGVPI 120

Query: 121 PQAPAGLAGPVRGVGGPSQQVMTPQGRGTVAAAAAAATASIAGAPTQYPPGRGGPPPPMG 180
           PQAPAGLAGPVRGVGGPSQQVMTPQGRGTVAAAA AATASIAGAPTQYPPGRG PPPP+G
Sbjct: 121 PQAPAGLAGPVRGVGGPSQQVMTPQGRGTVAAAAVAATASIAGAPTQYPPGRGTPPPPVG 180

Query: 181 RGAPPPGMMGPPPGMRPPMGPPMGIPPGRGTPMGMPPPGMRPPPPGMRG 229
           R  PPPG+M PPPGMRPPMGPP+G+PP RGTP+GMPPPGMRPPPPG+RG
Sbjct: 181 RATPPPGIMAPPPGMRPPMGPPIGLPPARGTPIGMPPPGMRPPPPGIRG 229


>gi|13027648 small nuclear ribonucleoprotein polypeptide N [Homo
           sapiens]
          Length = 240

 Score =  454 bits (1167), Expect = e-128
 Identities = 212/229 (92%), Positives = 222/229 (96%)

Query: 1   MTVGKSSKMLQHIDYRMRCILQDGRIFIGTFKAFDKHMNLILCDCDEFRKIKPKNSKQAE 60
           MTVGKSSKMLQHIDYRMRCILQDGRIFIGTFKAFDKHMNLILCDCDEFRKIKPKN+KQ E
Sbjct: 1   MTVGKSSKMLQHIDYRMRCILQDGRIFIGTFKAFDKHMNLILCDCDEFRKIKPKNAKQPE 60

Query: 61  REEKRVLGLVLLRGENLVSMTVEGPPPKDTGIARVPLAGAAGGPGIGRAAGRGIPAGVPM 120
           REEKRVLGLVLLRGENLVSMTVEGPPPKDTGIARVPLAGAAGGPG+GRAAGRG+PAGVP+
Sbjct: 61  REEKRVLGLVLLRGENLVSMTVEGPPPKDTGIARVPLAGAAGGPGVGRAAGRGVPAGVPI 120

Query: 121 PQAPAGLAGPVRGVGGPSQQVMTPQGRGTVAAAAAAATASIAGAPTQYPPGRGGPPPPMG 180
           PQAPAGLAGPVRGVGGPSQQVMTPQGRGTVAAAA AATASIAGAPTQYPPGRG PPPP+G
Sbjct: 121 PQAPAGLAGPVRGVGGPSQQVMTPQGRGTVAAAAVAATASIAGAPTQYPPGRGTPPPPVG 180

Query: 181 RGAPPPGMMGPPPGMRPPMGPPMGIPPGRGTPMGMPPPGMRPPPPGMRG 229
           R  PPPG+M PPPGMRPPMGPP+G+PP RGTP+GMPPPGMRPPPPG+RG
Sbjct: 181 RATPPPGIMAPPPGMRPPMGPPIGLPPARGTPIGMPPPGMRPPPPGIRG 229


>gi|13027646 small nuclear ribonucleoprotein polypeptide N [Homo
           sapiens]
          Length = 240

 Score =  454 bits (1167), Expect = e-128
 Identities = 212/229 (92%), Positives = 222/229 (96%)

Query: 1   MTVGKSSKMLQHIDYRMRCILQDGRIFIGTFKAFDKHMNLILCDCDEFRKIKPKNSKQAE 60
           MTVGKSSKMLQHIDYRMRCILQDGRIFIGTFKAFDKHMNLILCDCDEFRKIKPKN+KQ E
Sbjct: 1   MTVGKSSKMLQHIDYRMRCILQDGRIFIGTFKAFDKHMNLILCDCDEFRKIKPKNAKQPE 60

Query: 61  REEKRVLGLVLLRGENLVSMTVEGPPPKDTGIARVPLAGAAGGPGIGRAAGRGIPAGVPM 120
           REEKRVLGLVLLRGENLVSMTVEGPPPKDTGIARVPLAGAAGGPG+GRAAGRG+PAGVP+
Sbjct: 61  REEKRVLGLVLLRGENLVSMTVEGPPPKDTGIARVPLAGAAGGPGVGRAAGRGVPAGVPI 120

Query: 121 PQAPAGLAGPVRGVGGPSQQVMTPQGRGTVAAAAAAATASIAGAPTQYPPGRGGPPPPMG 180
           PQAPAGLAGPVRGVGGPSQQVMTPQGRGTVAAAA AATASIAGAPTQYPPGRG PPPP+G
Sbjct: 121 PQAPAGLAGPVRGVGGPSQQVMTPQGRGTVAAAAVAATASIAGAPTQYPPGRGTPPPPVG 180

Query: 181 RGAPPPGMMGPPPGMRPPMGPPMGIPPGRGTPMGMPPPGMRPPPPGMRG 229
           R  PPPG+M PPPGMRPPMGPP+G+PP RGTP+GMPPPGMRPPPPG+RG
Sbjct: 181 RATPPPGIMAPPPGMRPPMGPPIGLPPARGTPIGMPPPGMRPPPPGIRG 229


>gi|13027644 small nuclear ribonucleoprotein polypeptide N [Homo
           sapiens]
          Length = 240

 Score =  454 bits (1167), Expect = e-128
 Identities = 212/229 (92%), Positives = 222/229 (96%)

Query: 1   MTVGKSSKMLQHIDYRMRCILQDGRIFIGTFKAFDKHMNLILCDCDEFRKIKPKNSKQAE 60
           MTVGKSSKMLQHIDYRMRCILQDGRIFIGTFKAFDKHMNLILCDCDEFRKIKPKN+KQ E
Sbjct: 1   MTVGKSSKMLQHIDYRMRCILQDGRIFIGTFKAFDKHMNLILCDCDEFRKIKPKNAKQPE 60

Query: 61  REEKRVLGLVLLRGENLVSMTVEGPPPKDTGIARVPLAGAAGGPGIGRAAGRGIPAGVPM 120
           REEKRVLGLVLLRGENLVSMTVEGPPPKDTGIARVPLAGAAGGPG+GRAAGRG+PAGVP+
Sbjct: 61  REEKRVLGLVLLRGENLVSMTVEGPPPKDTGIARVPLAGAAGGPGVGRAAGRGVPAGVPI 120

Query: 121 PQAPAGLAGPVRGVGGPSQQVMTPQGRGTVAAAAAAATASIAGAPTQYPPGRGGPPPPMG 180
           PQAPAGLAGPVRGVGGPSQQVMTPQGRGTVAAAA AATASIAGAPTQYPPGRG PPPP+G
Sbjct: 121 PQAPAGLAGPVRGVGGPSQQVMTPQGRGTVAAAAVAATASIAGAPTQYPPGRGTPPPPVG 180

Query: 181 RGAPPPGMMGPPPGMRPPMGPPMGIPPGRGTPMGMPPPGMRPPPPGMRG 229
           R  PPPG+M PPPGMRPPMGPP+G+PP RGTP+GMPPPGMRPPPPG+RG
Sbjct: 181 RATPPPGIMAPPPGMRPPMGPPIGLPPARGTPIGMPPPGMRPPPPGIRG 229


>gi|4507135 small nuclear ribonucleoprotein polypeptide N [Homo
           sapiens]
          Length = 240

 Score =  454 bits (1167), Expect = e-128
 Identities = 212/229 (92%), Positives = 222/229 (96%)

Query: 1   MTVGKSSKMLQHIDYRMRCILQDGRIFIGTFKAFDKHMNLILCDCDEFRKIKPKNSKQAE 60
           MTVGKSSKMLQHIDYRMRCILQDGRIFIGTFKAFDKHMNLILCDCDEFRKIKPKN+KQ E
Sbjct: 1   MTVGKSSKMLQHIDYRMRCILQDGRIFIGTFKAFDKHMNLILCDCDEFRKIKPKNAKQPE 60

Query: 61  REEKRVLGLVLLRGENLVSMTVEGPPPKDTGIARVPLAGAAGGPGIGRAAGRGIPAGVPM 120
           REEKRVLGLVLLRGENLVSMTVEGPPPKDTGIARVPLAGAAGGPG+GRAAGRG+PAGVP+
Sbjct: 61  REEKRVLGLVLLRGENLVSMTVEGPPPKDTGIARVPLAGAAGGPGVGRAAGRGVPAGVPI 120

Query: 121 PQAPAGLAGPVRGVGGPSQQVMTPQGRGTVAAAAAAATASIAGAPTQYPPGRGGPPPPMG 180
           PQAPAGLAGPVRGVGGPSQQVMTPQGRGTVAAAA AATASIAGAPTQYPPGRG PPPP+G
Sbjct: 121 PQAPAGLAGPVRGVGGPSQQVMTPQGRGTVAAAAVAATASIAGAPTQYPPGRGTPPPPVG 180

Query: 181 RGAPPPGMMGPPPGMRPPMGPPMGIPPGRGTPMGMPPPGMRPPPPGMRG 229
           R  PPPG+M PPPGMRPPMGPP+G+PP RGTP+GMPPPGMRPPPPG+RG
Sbjct: 181 RATPPPGIMAPPPGMRPPMGPPIGLPPARGTPIGMPPPGMRPPPPGIRG 229


>gi|169216044 PREDICTED: similar to hCG2041320 [Homo sapiens]
          Length = 318

 Score =  234 bits (597), Expect = 5e-62
 Identities = 114/141 (80%), Positives = 123/141 (87%)

Query: 7   SKMLQHIDYRMRCILQDGRIFIGTFKAFDKHMNLILCDCDEFRKIKPKNSKQAEREEKRV 66
           +++ QHIDYRM+CILQ+G IF G FKAFDKH+NLILCDCDEFRKIKPKN KQ E EEK  
Sbjct: 152 ARLQQHIDYRMKCILQEGTIFFGIFKAFDKHVNLILCDCDEFRKIKPKNVKQPELEEKHF 211

Query: 67  LGLVLLRGENLVSMTVEGPPPKDTGIARVPLAGAAGGPGIGRAAGRGIPAGVPMPQAPAG 126
            GLVLL GENLVSMTVEG PPK TGIARVPLAGAAGGPG+ RAAGRG+ AGVP+PQAP G
Sbjct: 212 WGLVLLHGENLVSMTVEGLPPKYTGIARVPLAGAAGGPGVVRAAGRGVSAGVPIPQAPGG 271

Query: 127 LAGPVRGVGGPSQQVMTPQGR 147
           LAGPV GVGGPSQQVMTPQ R
Sbjct: 272 LAGPVPGVGGPSQQVMTPQRR 292


>gi|169215838 PREDICTED: similar to hCG2041320 [Homo sapiens]
          Length = 318

 Score =  234 bits (597), Expect = 5e-62
 Identities = 114/141 (80%), Positives = 123/141 (87%)

Query: 7   SKMLQHIDYRMRCILQDGRIFIGTFKAFDKHMNLILCDCDEFRKIKPKNSKQAEREEKRV 66
           +++ QHIDYRM+CILQ+G IF G FKAFDKH+NLILCDCDEFRKIKPKN KQ E EEK  
Sbjct: 152 ARLQQHIDYRMKCILQEGTIFFGIFKAFDKHVNLILCDCDEFRKIKPKNVKQPELEEKHF 211

Query: 67  LGLVLLRGENLVSMTVEGPPPKDTGIARVPLAGAAGGPGIGRAAGRGIPAGVPMPQAPAG 126
            GLVLL GENLVSMTVEG PPK TGIARVPLAGAAGGPG+ RAAGRG+ AGVP+PQAP G
Sbjct: 212 WGLVLLHGENLVSMTVEGLPPKYTGIARVPLAGAAGGPGVVRAAGRGVSAGVPIPQAPGG 271

Query: 127 LAGPVRGVGGPSQQVMTPQGR 147
           LAGPV GVGGPSQQVMTPQ R
Sbjct: 272 LAGPVPGVGGPSQQVMTPQRR 292


>gi|169215637 PREDICTED: similar to hCG2041320 [Homo sapiens]
          Length = 318

 Score =  234 bits (597), Expect = 5e-62
 Identities = 114/141 (80%), Positives = 123/141 (87%)

Query: 7   SKMLQHIDYRMRCILQDGRIFIGTFKAFDKHMNLILCDCDEFRKIKPKNSKQAEREEKRV 66
           +++ QHIDYRM+CILQ+G IF G FKAFDKH+NLILCDCDEFRKIKPKN KQ E EEK  
Sbjct: 152 ARLQQHIDYRMKCILQEGTIFFGIFKAFDKHVNLILCDCDEFRKIKPKNVKQPELEEKHF 211

Query: 67  LGLVLLRGENLVSMTVEGPPPKDTGIARVPLAGAAGGPGIGRAAGRGIPAGVPMPQAPAG 126
            GLVLL GENLVSMTVEG PPK TGIARVPLAGAAGGPG+ RAAGRG+ AGVP+PQAP G
Sbjct: 212 WGLVLLHGENLVSMTVEGLPPKYTGIARVPLAGAAGGPGVVRAAGRGVSAGVPIPQAPGG 271

Query: 127 LAGPVRGVGGPSQQVMTPQGR 147
           LAGPV GVGGPSQQVMTPQ R
Sbjct: 272 LAGPVPGVGGPSQQVMTPQRR 292


>gi|5032069 splicing factor 3b, subunit 4 [Homo sapiens]
          Length = 424

 Score = 75.5 bits (184), Expect = 4e-14
 Identities = 60/149 (40%), Positives = 64/149 (42%), Gaps = 37/149 (24%)

Query: 85  PPPKDTGIAR--VPLAGA--AGGPGIGRAAGRGIPAGVPMPQAPAGLAGPVRGVGGPSQQ 140
           PPP   G A    P AG   AG PG G +         P P  P G+  P     G SQ 
Sbjct: 263 PPPMPPGAAGHGPPSAGTPGAGHPGHGHSH--------PHPFPPGGMPHP-----GMSQM 309

Query: 141 VMTPQGRGTVAAAAAAATASIAGAPTQYPPGRGGPPPPMGRGAPPPGMM--GPPPGMRPP 198
            +   G   +            G P   PPG GG PPP     PPPGM   GPPP   PP
Sbjct: 310 QLAHHGPHGL------------GHPHAGPPGSGGQPPPR----PPPGMPHPGPPPMGMPP 353

Query: 199 MGPPMGIPPGRGTPMGMPPPGMRPPPPGM 227
            GPP G P G   P  MPP GMR PPP M
Sbjct: 354 RGPPFGSPMGHPGP--MPPHGMRGPPPLM 380



 Score = 53.5 bits (127), Expect = 1e-07
 Identities = 38/99 (38%), Positives = 44/99 (44%), Gaps = 21/99 (21%)

Query: 148 GTVAAAAAAATASIAGAPTQYPPGRGGPPPP---------MGRGAPPPGMMGPPPGMRPP 198
           G+ A    AA   ++ A   +      PPPP         +G G PPPGM  PPPG  PP
Sbjct: 188 GSAAERLLAAQNPLSQADRPHQLFADAPPPPSAPNPVVSSLGSGLPPPGM--PPPGSFPP 245

Query: 199 MGPPMG-IPPGRGTPMGMPPP-------GMRPPPPGMRG 229
             PP G +PPG   P  MPPP       G  PP  G  G
Sbjct: 246 PVPPPGALPPG--IPPAMPPPPMPPGAAGHGPPSAGTPG 282



 Score = 45.4 bits (106), Expect = 4e-05
 Identities = 50/154 (32%), Positives = 53/154 (34%), Gaps = 24/154 (15%)

Query: 83  EGPPPKDTGIARVPLAGAAGGPGIGRAAGRGIPAGVPMPQAPAGLAGPVRGVGGPSQQVM 142
           + PPP       V   G+   P      G   P   P P  P G   P    G P     
Sbjct: 213 DAPPPPSAPNPVVSSLGSGLPP-----PGMPPPGSFPPPVPPPGALPP----GIPPAMPP 263

Query: 143 TPQGRGTVAAAAAAATASIAGAPTQYPPGRGGPPPPMGRGAPPPGMM-------GPPPGM 195
            P   G       +A    AG P     G   P P    G P PGM        GP    
Sbjct: 264 PPMPPGAAGHGPPSAGTPGAGHPGH---GHSHPHPFPPGGMPHPGMSQMQLAHHGPHGLG 320

Query: 196 RPPMGPPM--GIPPGRGTPMGMPPPGMRPPPPGM 227
            P  GPP   G PP R  P GMP PG  PPP GM
Sbjct: 321 HPHAGPPGSGGQPPPRPPP-GMPHPG--PPPMGM 351



 Score = 31.6 bits (70), Expect = 0.60
 Identities = 33/115 (28%), Positives = 36/115 (31%), Gaps = 30/115 (26%)

Query: 85  PPPKDTGIARVPLAGAAGGPGIGRAAGRGIPAGVPMPQAPAGLAGPVRGVGGPSQQVMTP 144
           PPP        P+     GP  G       P G P P  P G+ GP          +M P
Sbjct: 337 PPPGMPHPGPPPMGMPPRGPPFGS------PMGHPGPMPPHGMRGP--------PPLMPP 382

Query: 145 QGRGTVAAAAAAATASIAGAPTQYPPG--RGGPPPPMGRGAPPPGMMGPPPGMRP 197
            G                G P   P G  RG  PPP     PP    GP  G  P
Sbjct: 383 HG--------------YTGPPRPPPYGYQRGPLPPPRPTPRPPVPPRGPLRGPLP 423


>gi|40805823 collagen, type XXII, alpha 1 [Homo sapiens]
          Length = 1626

 Score = 66.2 bits (160), Expect = 2e-11
 Identities = 58/152 (38%), Positives = 64/152 (42%), Gaps = 26/152 (17%)

Query: 97  LAGAAGGPGIGRAAGRGIPAGVPMPQAPAGLAGPVRGVGGPSQQVMTPQGRGTVAAAAAA 156
           L G  G PG     GR  P+GV  PQ   G  GP    G P   V   Q  G      A 
Sbjct: 606 LDGFPGKPGDTGQQGRPGPSGVAGPQGEKGDVGPAGPPGVPGSVV---QQEGLKGEQGAP 662

Query: 157 ATASIAGAPTQYPPGRGGPPPPMGRGAPP--------PGMMGPPP-----GMRPPMGPPM 203
                 GAP   PPG  GP  P GR  PP         G MGPP      G++ P GPP 
Sbjct: 663 GPRGHQGAPG--PPGARGPIGPEGRDGPPGLQGLRGKKGDMGPPGIPGLLGLQGPPGPP- 719

Query: 204 GI--PPGRGTPMGMPP----PGMRPPPPGMRG 229
           G+  PPG G   G+P     PG +P PPG  G
Sbjct: 720 GVPGPPGPGGSPGLPGEIGFPG-KPGPPGPTG 750



 Score = 54.7 bits (130), Expect = 7e-08
 Identities = 60/192 (31%), Positives = 73/192 (38%), Gaps = 42/192 (21%)

Query: 58  QAEREEKRVLGLVLLRGENLVSMTVEGPPPKDTGIARVPLAGAAGGPGI-GRAAGRGIPA 116
           Q E+ EK  LGL              GPP +D         G  G PG+ G    RG   
Sbjct: 526 QGEKGEKGSLGL-------------PGPPGRDGSKGMRGEPGELGEPGLPGEVGMRG--- 569

Query: 117 GVPMPQAPAGLAGPVRGVGGPSQQVMTPQGRGTVAAAAAAATASIAGAPTQYPPGRGGPP 176
               PQ P GL GP   VG P  Q    + +GT             G P     G+ G P
Sbjct: 570 ----PQGPPGLPGPPGRVGAPGLQGERGE-KGTRGEKGERGLDGFPGKPGD--TGQQGRP 622

Query: 177 PPMGRGAP--PPGMMGP--PPGMRPPMGPPMGIPPGRGTP-----MGMP-PPGMRPP--- 223
            P G   P    G +GP  PPG+   +    G+   +G P      G P PPG R P   
Sbjct: 623 GPSGVAGPQGEKGDVGPAGPPGVPGSVVQQEGLKGEQGAPGPRGHQGAPGPPGARGPIGP 682

Query: 224 -----PPGMRGL 230
                PPG++GL
Sbjct: 683 EGRDGPPGLQGL 694



 Score = 53.5 bits (127), Expect = 1e-07
 Identities = 65/207 (31%), Positives = 75/207 (36%), Gaps = 44/207 (21%)

Query: 58  QAEREEKRVLGLVLLRGENLVSMTVEGPP--PKDTGIARVPLAGAAGGP-----GIGRAA 110
           Q ER EK   G    RG       ++G P  P DTG    P      GP      +G A 
Sbjct: 589 QGERGEKGTRGEKGERG-------LDGFPGKPGDTGQQGRPGPSGVAGPQGEKGDVGPAG 641

Query: 111 GRGIPA------------GVPMPQAPAGLAGP--VRGVGGPSQQVMTPQGRGTVAAAAAA 156
             G+P             G P P+   G  GP   RG  GP  +   P  +G        
Sbjct: 642 PPGVPGSVVQQEGLKGEQGAPGPRGHQGAPGPPGARGPIGPEGRDGPPGLQGLRGKKGDM 701

Query: 157 ATASIAGA-PTQYPPGRGGPPPPMGRGAPP--------PGMMGPPPGMRP-----PMGPP 202
               I G    Q PPG  G P P G G  P        PG  GPP    P     P GPP
Sbjct: 702 GPPGIPGLLGLQGPPGPPGVPGPPGPGGSPGLPGEIGFPGKPGPPGPTGPPGKDGPNGPP 761

Query: 203 MGIPPGRGTPMGMPPPGMRPPPPGMRG 229
            G P  +G P      G+ P  PG+RG
Sbjct: 762 -GPPGTKGEPGERGEDGL-PGKPGLRG 786



 Score = 50.4 bits (119), Expect = 1e-06
 Identities = 51/169 (30%), Positives = 60/169 (35%), Gaps = 32/169 (18%)

Query: 86   PPKDTGIARVPLAGAAGGPGIGRAAGRGIPAGVPMPQAPAGLAGPVRGVGGPSQQVMTPQ 145
            PP   G+  +P  G  G  G+    GR    G      P GL GP  G+ GP        
Sbjct: 1118 PPGPPGLPGLP--GFKGDKGVPGKPGREGTEGKKGEAGPPGLPGPP-GIAGPQGSQGERG 1174

Query: 146  GRGTVAAAAAAATASIAGAPTQYPPGRGGPPPP---MGRGAPP-----PGMMGPPPGMRP 197
              G V          + G     PPG  GPP      G   PP     PG  GP PG + 
Sbjct: 1175 ADGEVGQKGDQGHPGVPGF--MGPPGNPGPPGADGIAGAAGPPGIQGSPGKEGP-PGPQG 1231

Query: 198  PMGPPMGIP-----------------PGRGTPMGMPPPGMRPPPPGMRG 229
            P G P GIP                 PG+    G+P P     PPG +G
Sbjct: 1232 PSGLP-GIPGEEGKEGRDGKPGPPGEPGKAGEPGLPGPEGARGPPGFKG 1279



 Score = 49.7 bits (117), Expect = 2e-06
 Identities = 54/163 (33%), Positives = 63/163 (38%), Gaps = 29/163 (17%)

Query: 84   GPPPKDTGIARVPLAGAAGGPGIGRAAGRGIPAGVPMPQAPAGLAGPVRGVGGPSQQVMT 143
            GPP  D       +AGAAG PGI  + G+    G P PQ P+GL G + G  G   +   
Sbjct: 1201 GPPGADG------IAGAAGPPGIQGSPGK---EGPPGPQGPSGLPG-IPGEEGKEGRDGK 1250

Query: 144  PQGRGTVAAAAAAATASIAGAPTQYPP------GRGGPPPPMGRGAPP--PGMMGPP--- 192
            P   G    A         GA  + PP      G  G P P G       PG  G P   
Sbjct: 1251 PGPPGEPGKAGEPGLPGPEGA--RGPPGFKGHTGDSGAPGPRGESGAMGLPGQEGLPGKD 1308

Query: 193  --PGMRPPMGP--PMGIPPGRGTP--MGMPPPGMRPPPPGMRG 229
               G   P GP  P G P   G+P   G P P   P   G +G
Sbjct: 1309 GDTGPTGPQGPQGPRGPPGKNGSPGSPGEPGPSGTPGQKGSKG 1351



 Score = 49.7 bits (117), Expect = 2e-06
 Identities = 50/166 (30%), Positives = 59/166 (35%), Gaps = 36/166 (21%)

Query: 98   AGAAGGPGIGRAAGRGIPAGVPMPQAPAGLAGPVRGVGGPSQQVMTPQGRGTVAAAAAAA 157
            +GA G PG     G+    G   PQ P G  GP    G P      P   GT     +  
Sbjct: 1293 SGAMGLPGQEGLPGKDGDTGPTGPQGPQGPRGPPGKNGSPGSPG-EPGPSGTPGQKGSKG 1351

Query: 158  TASIAGAPTQYPPGRGGPPPPMGRGAPP----PGMMGPP--------PGMRPPMGPP--- 202
                 G P    P RG P  P  +G P     PG  G P        PG++   GPP   
Sbjct: 1352 ENGSPGLPGFLGP-RGPPGEPGEKGVPGKEGVPGKPGEPGFKGERGDPGIKGDKGPPGGK 1410

Query: 203  -----MGIP--------------PGRGTPMGMPPPGMRPPPPGMRG 229
                  GIP              PG   P+G P P  +P  PG+RG
Sbjct: 1411 GQPGDPGIPGHKGHTGLMGPQGLPGENGPVGPPGPPGQPGFPGLRG 1456



 Score = 45.8 bits (107), Expect = 3e-05
 Identities = 52/176 (29%), Positives = 67/176 (38%), Gaps = 42/176 (23%)

Query: 89   DTGIARVPLAGAAGGPGI-GRAAGRGIPAGVPMPQAPAGLAGPVRGVGGPSQQVMTPQGR 147
            D GI      G +G PG  G    RG+P G P PQ PAG  G     G P ++   P G+
Sbjct: 1041 DPGIGVAGPPGPSGPPGDKGSPGSRGLP-GFPGPQGPAGRDG---APGNPGER--GPPGK 1094

Query: 148  GTVAAAAAAATASIAGAP--TQYPPGRGGPPPPMG----RGAP----------------P 185
              +++  +    ++         PPG  G P   G    +G P                P
Sbjct: 1095 PGLSSLLSPGDINLLAKDVCNDCPPGPPGLPGLPGFKGDKGVPGKPGREGTEGKKGEAGP 1154

Query: 186  PGMMGPPPGMRPPMGP-----------PMGIPPGRGTPMGMPPPGMRPPPPGMRGL 230
            PG+ G PPG+  P G              G     G P  M PPG  P PPG  G+
Sbjct: 1155 PGLPG-PPGIAGPQGSQGERGADGEVGQKGDQGHPGVPGFMGPPG-NPGPPGADGI 1208



 Score = 45.4 bits (106), Expect = 4e-05
 Identities = 50/156 (32%), Positives = 60/156 (38%), Gaps = 26/156 (16%)

Query: 99   GAAGGPGI-GRAAGRGI--PAGVPMPQAPAGLAGPVRGVGGPSQQVMTPQ----GRGTVA 151
            G  G PGI G     G+  P G+P    P G  GP    G P  +  +P      R    
Sbjct: 1411 GQPGDPGIPGHKGHTGLMGPQGLPGENGPVGPPGPPGQPGFPGLRGESPSMETLRRLIQE 1470

Query: 152  AAAAAATASIAGAPTQYPP-------GRGGPPPPMGRGAPP--PGMMGPP-----PGMRP 197
                     +A    Q PP       GR GPP P G+   P   G MG P      G+  
Sbjct: 1471 ELGKQLETRLAYLLAQMPPAYMKSSQGRPGPPGPPGKDGLPGRAGPMGEPGRPGQGGLEG 1530

Query: 198  PMGP--PMGIPPGRGTPMGMPPPGMRPP--PPGMRG 229
            P GP  P G    +G P G P  G+R    PPG+ G
Sbjct: 1531 PSGPIGPKGERGAKGDP-GAPGVGLRGEMGPPGIPG 1565



 Score = 45.1 bits (105), Expect = 5e-05
 Identities = 53/171 (30%), Positives = 64/171 (37%), Gaps = 44/171 (25%)

Query: 78  VSMTVEGPPPKDTGIARVPLAGA--------------AGGPGIGRAAGRGIPAGVPMPQA 123
           V++  E PPP      R P  G+              AG  G    AG   P G+P P+ 
Sbjct: 445 VTVVTEPPPPPPP--QRPPTPGSEQIGFLKTINCSCPAGEKGEMGVAG---PMGLPGPKG 499

Query: 124 PAGLAGPVRGVGGPSQQVMTPQGRGTVAAAAAAATASIAGAPTQYPPGRGGPPPPMGRGA 183
             G  GPV G  GP  +     G G           S+ G P   PPGR G     G   
Sbjct: 500 DIGAIGPV-GAPGPKGE-KGDVGIGPFGQGEKGEKGSL-GLPG--PPGRDGSKGMRGE-- 552

Query: 184 PPPGMMGPP-----PGMRPPMGPPMGIPPGRGTPMGMPPPGMRPPPPGMRG 229
             PG +G P      GMR P GPP           G+P P  R   PG++G
Sbjct: 553 --PGELGEPGLPGEVGMRGPQGPP-----------GLPGPPGRVGAPGLQG 590



 Score = 43.5 bits (101), Expect = 2e-04
 Identities = 54/171 (31%), Positives = 64/171 (37%), Gaps = 31/171 (18%)

Query: 82   VEGPPPKDTGIARVPLAGAAGGPG-IGRAAGRGIPAGVPMPQAPAGLAGP-VRGVGGPSQ 139
            + G P KD        AG  G PG +G     G P G+P P        P +RG  G   
Sbjct: 941  LRGTPGKDGERGEKGAAGEEGSPGPVGPRGDPGAP-GLPGPPGKGKDGEPGLRGSPGLPG 999

Query: 140  QVMTPQGRGTVAAAAAAATAS-----------IAGAP-TQYPPGRG--GPPPPMGRGAPP 185
             + T    G V  +   A              I G+P ++  PG G  GPP P G    P
Sbjct: 1000 PLGTKAACGKVRGSENCALGGQCVKGDRGAPGIPGSPGSRGDPGIGVAGPPGPSG----P 1055

Query: 186  PGMMGPP-----PGMRPPMGPPMGIPPGRGTPMGMPPPGMRPPPPGMRGLL 231
            PG  G P     PG   P G P G     G P    PPG     PG+  LL
Sbjct: 1056 PGDKGSPGSRGLPGFPGPQG-PAGRDGAPGNPGERGPPG----KPGLSSLL 1101



 Score = 43.1 bits (100), Expect = 2e-04
 Identities = 50/162 (30%), Positives = 58/162 (35%), Gaps = 31/162 (19%)

Query: 99   GAAGGPGIGRAAGRGIPAGVPMPQAPAGLAGP--VRGVGGPSQQVMTPQGRGTVAAAAAA 156
            GA G PG     G     G P P  P G  G   +RG  G   +       G   +    
Sbjct: 907  GAHGAPGAAGNPGAPGHVGAPGPSGPPGSVGAPGLRGTPGKDGERGEKGAAGEEGSPGPV 966

Query: 157  ATASIAGAP-TQYPPGRGGPPPPMGRGAPP-PGMMGPP-------------------PGM 195
                  GAP    PPG+G    P  RG+P  PG +G                      G 
Sbjct: 967  GPRGDPGAPGLPGPPGKGKDGEPGLRGSPGLPGPLGTKAACGKVRGSENCALGGQCVKGD 1026

Query: 196  RPPMGPPMGIPPGRGTP-MGMP-PPGMRPPP-----PGMRGL 230
            R   G P G P  RG P +G+  PPG   PP     PG RGL
Sbjct: 1027 RGAPGIP-GSPGSRGDPGIGVAGPPGPSGPPGDKGSPGSRGL 1067



 Score = 40.8 bits (94), Expect = 0.001
 Identities = 52/177 (29%), Positives = 59/177 (33%), Gaps = 37/177 (20%)

Query: 83   EGPPPKDTGIARVPLAGAAGGPGIGRAAGRG----IPAGV--PMPQAPAGLAGPVRGVGG 136
            +GP  +D         G  G PG+      G    +   V    P  P GL G + G  G
Sbjct: 1074 QGPAGRDGAPGNPGERGPPGKPGLSSLLSPGDINLLAKDVCNDCPPGPPGLPG-LPGFKG 1132

Query: 137  PSQQVMTPQGRGTVAAAAAAATASIAGAPTQYPPGRGGPPPPMG-RGAPP---------- 185
                   P   GT      A    + G     PPG  GP    G RGA            
Sbjct: 1133 DKGVPGKPGREGTEGKKGEAGPPGLPG-----PPGIAGPQGSQGERGADGEVGQKGDQGH 1187

Query: 186  ---PGMMGPPPGMRPP--------MGPPMGI--PPGRGTPMGMPPPGMRPPPPGMRG 229
               PG MGPP    PP         GPP GI   PG+  P G   P   P  PG  G
Sbjct: 1188 PGVPGFMGPPGNPGPPGADGIAGAAGPP-GIQGSPGKEGPPGPQGPSGLPGIPGEEG 1243



 Score = 38.1 bits (87), Expect = 0.006
 Identities = 37/120 (30%), Positives = 42/120 (35%), Gaps = 19/120 (15%)

Query: 99   GAAGGPGIGRAAGRGIPAGVPMPQAPAGLAGPVRGVGGPSQQVMTPQGRGTVAAAAAAAT 158
            G  G PG     GR  P G P      GL GP   +G        P+G         A  
Sbjct: 1500 GPPGPPGKDGLPGRAGPMGEPGRPGQGGLEGPSGPIG--------PKGERGAKGDPGAPG 1551

Query: 159  ASIAGAPTQYPPGRGGPPPPMG---RGAP----PPGMMGPP--PGMRPPMGPPMGIPPGR 209
              + G     PPG  G P   G    G P    P G  GP   PG+  P GPP    P +
Sbjct: 1552 VGLRG--EMGPPGIPGQPGEPGYAKDGLPGIPGPQGETGPAGHPGLPGPPGPPGQCDPSQ 1609



 Score = 37.4 bits (85), Expect = 0.011
 Identities = 38/119 (31%), Positives = 40/119 (33%), Gaps = 18/119 (15%)

Query: 84   GPPPKDTGIARVPLAGAAGGPGIGRAAGRGIPAGVPMPQAPAGLAGPVRGVGGPSQQVMT 143
            GPP KD    R    G  G PG G   G   P+G   P  P G  G     G P      
Sbjct: 1503 GPPGKDGLPGRAGPMGEPGRPGQGGLEG---PSG---PIGPKGERGAKGDPGAP------ 1550

Query: 144  PQGRGTVAAAAAAATASIAGAPTQYPPGRGGPPPPMGRGAPP--PGMMGP--PPGMRPP 198
              G G              G P     G  G P P G   P   PG+ GP  PPG   P
Sbjct: 1551 --GVGLRGEMGPPGIPGQPGEPGYAKDGLPGIPGPQGETGPAGHPGLPGPPGPPGQCDP 1607



 Score = 36.6 bits (83), Expect = 0.019
 Identities = 57/183 (31%), Positives = 70/183 (38%), Gaps = 39/183 (21%)

Query: 60  EREEKRVLGLVLLRGENLVSMTVEGPPPKDTGIARVPLAGAAGGPGI-------GRAAGR 112
           ER E  + G   LRGE  +        P + G A +P  GA G PG+       G     
Sbjct: 772 ERGEDGLPGKPGLRGE--IGEQGLAGRPGEKGEAGLP--GAPGFPGVRGEKGDQGEKGEL 827

Query: 113 GIPAGVPMPQAPAGLAGPVRGVGGP-SQQVMTPQGR--GTVAAAAAAATASIAGAP-TQY 168
           G+P G+   +   G AGP    G P +  + TP  R  G            + G P  Q 
Sbjct: 828 GLP-GLKGDRGEKGEAGPAGPPGLPGTTSLFTPHPRMPGEQGPKGEKGDPGLPGEPGLQG 886

Query: 169 PPGR---GGPPPPMG-------RGAP-------PPGMMGPPPGMRPPMGPP--MGIPPGR 209
            PG     GP  P G        GAP        PG +G P     P GPP  +G P  R
Sbjct: 887 RPGELGPQGPTGPPGAKGQEGAHGAPGAAGNPGAPGHVGAP----GPSGPPGSVGAPGLR 942

Query: 210 GTP 212
           GTP
Sbjct: 943 GTP 945



 Score = 31.6 bits (70), Expect = 0.60
 Identities = 47/162 (29%), Positives = 54/162 (33%), Gaps = 56/162 (34%)

Query: 99   GAAGGPGI----GRAAGRGIPA--GVPMPQAPAGLAGPVRGVGGPSQQVMTPQGRGTVAA 152
            G  G PGI    G   G+G P   G+P  +   GL GP +G+ G +  V  P        
Sbjct: 1393 GERGDPGIKGDKGPPGGKGQPGDPGIPGHKGHTGLMGP-QGLPGENGPVGPP-------- 1443

Query: 153  AAAAATASIAGAPTQYP-PGRGGPPPPMGR---------------------GAPPPGMMG 190
                      G P Q   PG  G  P M                          PP  M 
Sbjct: 1444 ----------GPPGQPGFPGLRGESPSMETLRRLIQEELGKQLETRLAYLLAQMPPAYMK 1493

Query: 191  PPPGMRPPMGPPM--GIPPGRGTPMGMPPPGMRPPPPGMRGL 230
               G   P GPP   G+P GR  PMG       P  PG  GL
Sbjct: 1494 SSQGRPGPPGPPGKDGLP-GRAGPMG------EPGRPGQGGL 1528



 Score = 30.4 bits (67), Expect = 1.3
 Identities = 29/83 (34%), Positives = 34/83 (40%), Gaps = 14/83 (16%)

Query: 89   DTGIARVPLAGAAGGPGIGRAAGR------GIPAGVPMPQAPAGLAGPVRGVGGPSQQVM 142
            D G   V L G  G PGI    G       G+P G+P PQ   G AG   G+ GP     
Sbjct: 1546 DPGAPGVGLRGEMGPPGIPGQPGEPGYAKDGLP-GIPGPQGETGPAGH-PGLPGP----- 1598

Query: 143  TPQGRGTVAAAAAAATASIAGAP 165
             P   G    +  A  AS+A  P
Sbjct: 1599 -PGPPGQCDPSQCAYFASLAARP 1620



 Score = 30.0 bits (66), Expect = 1.7
 Identities = 25/81 (30%), Positives = 31/81 (38%), Gaps = 13/81 (16%)

Query: 161 IAGAPTQYPPGRGGPPPPMGRGAPPPGM----------MGPPPGMRPPMG--PPMGIPPG 208
           I   P Q       PPPP  +  P PG              P G +  MG   PMG+P  
Sbjct: 438 IPSGPCQVTVVTEPPPPPPPQRPPTPGSEQIGFLKTINCSCPAGEKGEMGVAGPMGLPGP 497

Query: 209 RGTPMGMPPPGMRPPPPGMRG 229
           +G    + P G  P P G +G
Sbjct: 498 KGDIGAIGPVG-APGPKGEKG 517


>gi|18641360 collectin sub-family member 12 [Homo sapiens]
          Length = 742

 Score = 65.9 bits (159), Expect = 3e-11
 Identities = 56/166 (33%), Positives = 76/166 (45%), Gaps = 20/166 (12%)

Query: 74  GENLVSMTV-EGPP-PKDTGIARVPLAGAAGGPGIGRAAGRGIPAGVPMPQAPAGLAGPV 131
           G+ + + T+ +GPP P+     R    G+ G PG     G+    G P P  PAG  GP+
Sbjct: 432 GQLIKNFTILQGPPGPRGPRGDR----GSQGPPGPTGNKGQKGEKGEPGPPGPAGERGPI 487

Query: 132 RGVGGPSQQVMTPQGRGTVAAAAAAATASIAGAP-TQYPPGRGGPPPPMGRGAPPPGMMG 190
              G P ++     G+G+  +     +    G P  Q P G  GPP P G+    PG  G
Sbjct: 488 GPAGPPGER----GGKGSKGSQGPKGSRGSPGKPGPQGPSGDPGPPGPPGKEG-LPGPQG 542

Query: 191 PP--PGMRPPMGPPMGIPPGRGTP-----MGMPPPGMRPPPPGMRG 229
           PP   G++  +G P G+P  RG P      GMP P   P PPG  G
Sbjct: 543 PPGFQGLQGTVGEP-GVPGPRGLPGLPGVPGMPGPKGPPGPPGPSG 587



 Score = 38.5 bits (88), Expect = 0.005
 Identities = 45/142 (31%), Positives = 52/142 (36%), Gaps = 28/142 (19%)

Query: 83  EGPPPKDTGIARVPLAGAAGGPGI----------GRAAGRGIPAGVPMPQAPAGLAGPVR 132
           E  PP   G  R P+ G AG PG           G    RG P G P PQ P+G  GP  
Sbjct: 474 EPGPPGPAG-ERGPI-GPAGPPGERGGKGSKGSQGPKGSRGSP-GKPGPQGPSGDPGPP- 529

Query: 133 GVGGPSQQVMT-PQG-------RGTVAAAAAAATASIAGAP----TQYPPGRGGPPPPMG 180
             G P ++ +  PQG       +GTV          + G P       P G  GPP P G
Sbjct: 530 --GPPGKEGLPGPQGPPGFQGLQGTVGEPGVPGPRGLPGLPGVPGMPGPKGPPGPPGPSG 587

Query: 181 RGAPPPGMMGPPPGMRPPMGPP 202
              P      P P       PP
Sbjct: 588 AVVPLALQNEPTPAPEDNGCPP 609



 Score = 35.0 bits (79), Expect = 0.054
 Identities = 28/69 (40%), Positives = 29/69 (42%), Gaps = 13/69 (18%)

Query: 171 GRGGPPPPMGRGAP-----PPGMMGPPPGMRPPMGPP--MGIP--PGRGTPMGMPPPGMR 221
           G  GPP P G   P     PPG  G   G +   GP    G P  PG   P G P P   
Sbjct: 473 GEPGPPGPAGERGPIGPAGPPGERGGK-GSKGSQGPKGSRGSPGKPGPQGPSGDPGP--- 528

Query: 222 PPPPGMRGL 230
           P PPG  GL
Sbjct: 529 PGPPGKEGL 537


>gi|39930517 sterile alpha motif domain containing 1 [Homo sapiens]
          Length = 538

 Score = 65.5 bits (158), Expect = 4e-11
 Identities = 47/145 (32%), Positives = 54/145 (37%), Gaps = 12/145 (8%)

Query: 86  PPKDTGIARVPLAGAAGGPGIGRAAGRGIPAGVPMPQAPAGLAGPVRGVGGPSQQVMTPQ 145
           PP+       P     G P    AA        P P AP   A P R     +     P 
Sbjct: 101 PPRRGATPPAPPRAPRGAPAAAAAAAPPPTPAPPPPPAPVAAAAPARAPRAAAAAATAPP 160

Query: 146 GRGTVAAAAAAATASIAGAPTQYPPGRGGPP---PPMG-RGAPPPGMMGPPPGMRPPMGP 201
             G       A  A+   AP   PP    PP   PP G R APPP +    P + PP  P
Sbjct: 161 SPGPAQPGPRAQRAAPLAAP---PPAPAAPPAVAPPAGPRRAPPPAVAAREPPLPPPPQP 217

Query: 202 PMGIPPGRGTPMGMPPPGMRPPPPG 226
           P   PP +  P   PPP  +PPP G
Sbjct: 218 P--APPQQQQP---PPPQPQPPPEG 237



 Score = 33.5 bits (75), Expect = 0.16
 Identities = 25/79 (31%), Positives = 25/79 (31%), Gaps = 10/79 (12%)

Query: 160 SIAGAPTQYPPGRGGPPPP---MGRGAP-------PPGMMGPPPGMRPPMGPPMGIPPGR 209
           S   A    PP RG  PP      RGAP       PP    PPP   P         P  
Sbjct: 92  SYRNAARVQPPRRGATPPAPPRAPRGAPAAAAAAAPPPTPAPPPPPAPVAAAAPARAPRA 151

Query: 210 GTPMGMPPPGMRPPPPGMR 228
                  PP   P  PG R
Sbjct: 152 AAAAATAPPSPGPAQPGPR 170



 Score = 33.1 bits (74), Expect = 0.21
 Identities = 36/120 (30%), Positives = 40/120 (33%), Gaps = 13/120 (10%)

Query: 85  PPPKDTGIARVPLAGAAGGPGIGRAAGRGIPAGVPMPQAP-----AGLAGPVRGVGGPSQ 139
           PPP     A V  A  A  P    AA    P+  P    P     A LA P      P  
Sbjct: 135 PPP-----APVAAAAPARAPRAAAAAATAPPSPGPAQPGPRAQRAAPLAAPPPAPAAPPA 189

Query: 140 QVMTPQGRGTVAAAAAAATASIAGAPTQ--YPPGRGGPPPPMGRGAPPPGMMGPPPGMRP 197
            V  P G       A AA       P Q   PP +  PPPP  +  P  G +      RP
Sbjct: 190 -VAPPAGPRRAPPPAVAAREPPLPPPPQPPAPPQQQQPPPPQPQPPPEGGAVRAGGAARP 248



 Score = 28.5 bits (62), Expect = 5.1
 Identities = 21/81 (25%), Positives = 29/81 (35%), Gaps = 22/81 (27%)

Query: 129 GPVRGVGGPSQQVMTPQGRGTVAAAAAAATASIAGAPTQYPPGRGGPPPPMGRGAPPPGM 188
           GP  G G  ++QV +          A+ AT   + +P   PPG+                
Sbjct: 394 GPAPGSG--TRQVFSMAAMNKEGGTASVATGPDSPSPVPLPPGK---------------- 435

Query: 189 MGPPPGMRPPMGPPMGIPPGR 209
               P +    G P G PPGR
Sbjct: 436 ----PALPGADGTPFGCPPGR 452


>gi|111118976 collagen, type II, alpha 1 isoform 1 precursor [Homo
           sapiens]
          Length = 1487

 Score = 65.1 bits (157), Expect = 5e-11
 Identities = 53/157 (33%), Positives = 60/157 (38%), Gaps = 26/157 (16%)

Query: 84  GPPPKDTGIARVPLAGAAGGPGIGRAAGRGIPAGVPMPQAPAGLAGP--VRGVGGPSQQV 141
           GPP  D         G AG  G   A G   P+G P PQ P G+ GP   RG  GP    
Sbjct: 837 GPPGADGQPGAKGEQGEAGQKGDAGAPGPQGPSGAPGPQGPTGVTGPKGARGAQGPPGAT 896

Query: 142 MTPQGRGTVAAAAAAATASIAGAPTQYPPGRGGPPPPMGRGAP--------PPGMMGPPP 193
             P   G V    +              PG  GPP P G+  P        PPG  G  P
Sbjct: 897 GFPGAAGRVGPPGSNGN-----------PGPPGPPGPSGKDGPKGARGDSGPPGRAG-EP 944

Query: 194 GMRPPMGPP-MGIPPGRGTPMGMPPPGMRPPPPGMRG 229
           G++ P GPP     PG   P G   P   P P G+ G
Sbjct: 945 GLQGPAGPPGEKGEPGDDGPSGAEGP---PGPQGLAG 978



 Score = 57.4 bits (137), Expect = 1e-08
 Identities = 51/158 (32%), Positives = 55/158 (34%), Gaps = 13/158 (8%)

Query: 84  GPPPKDTGIARVPLAGAAGGPGIGRAAGRGIPAGVPMPQAPAGLAGPVRGVGGPSQQVMT 143
           GPP        +   G  G PGI    G   P G P P  P G  GP  G  G       
Sbjct: 438 GPPGPQGATGPLGPKGQTGEPGIAGFKGEQGPKGEPGPAGPQGAPGPA-GEEGKRGARGE 496

Query: 144 PQGRGTVAAAAAAATASIAGAPTQ----YPPGRGGPPPPMGRGAP-----PPGMMGPP-- 192
           P G G +            G P Q     P G  G   P G   P      PG  G P  
Sbjct: 497 PGGVGPIGPPGERGAPGNRGFPGQDGLAGPKGAPGERGPSGLAGPKGANGDPGRPGEPGL 556

Query: 193 PGMRPPMGPPMGI-PPGRGTPMGMPPPGMRPPPPGMRG 229
           PG R   G P    P G+  P G P    RP PPG +G
Sbjct: 557 PGARGLTGRPGDAGPQGKVGPSGAPGEDGRPGPPGPQG 594



 Score = 55.8 bits (133), Expect = 3e-08
 Identities = 58/173 (33%), Positives = 60/173 (34%), Gaps = 41/173 (23%)

Query: 83  EGPPPKDTGIARVPLAGAAGGPG----------------IGRAAGRGIPA--GVPMPQAP 124
           EG P KD G     L G  G PG                 G A  RG P   G   P  P
Sbjct: 776 EGAPGKDGGRG---LTGPIGPPGPAGANGEKGEVGPPGPAGSAGARGAPGERGETGPPGP 832

Query: 125 AGLAGPVRGVGGPSQQVMTPQGRGTVAAAAAAATASIAGAP-TQYPPGRGGPPPPMGRGA 183
           AG AGP    G P          G       A     AGAP  Q P G  GP  P G   
Sbjct: 833 AGFAGPPGADGQP----------GAKGEQGEAGQKGDAGAPGPQGPSGAPGPQGPTGVTG 882

Query: 184 P--PPGMMGPP-----PGMRPPMGPPMGIPPGRGTPMGMPPPGMRPPPPGMRG 229
           P    G  GPP     PG    +GPP     G   P G P P  +  P G RG
Sbjct: 883 PKGARGAQGPPGATGFPGAAGRVGPPGS--NGNPGPPGPPGPSGKDGPKGARG 933



 Score = 52.8 bits (125), Expect = 3e-07
 Identities = 55/157 (35%), Positives = 62/157 (39%), Gaps = 26/157 (16%)

Query: 84   GPPPKDTGIARVP-LAGAAGGPGIGRAAGRGIPAGVPMPQAPAGLAGPVRGVGGPSQQVM 142
            GPP    G A  P L G AG PG     G   P+G   P  P GLAG    VG P Q+  
Sbjct: 936  GPP----GRAGEPGLQGPAGPPGEKGEPGDDGPSGAEGPPGPQGLAGQRGIVGLPGQR-- 989

Query: 143  TPQGRGTVAAAAAAATASIAGAPTQYPPGRGGPPPPMGRGAPPPGMMGP--------PPG 194
                RG       +      GAP     G  GPP P+G    PPG+ GP         PG
Sbjct: 990  --GERGFPGLPGPSGEPGKQGAPG--ASGDRGPPGPVG----PPGLTGPAGEPGREGSPG 1041

Query: 195  MRPPMG--PPMGIPPGRGTPMGMPPPGMRPPPPGMRG 229
               P G     G+   RG    +  PG  P PPG  G
Sbjct: 1042 ADGPPGRDGAAGVKGDRGETGAVGAPG-APGPPGSPG 1077



 Score = 52.4 bits (124), Expect = 3e-07
 Identities = 52/176 (29%), Positives = 59/176 (33%), Gaps = 35/176 (19%)

Query: 83  EGPPPKDTGIARVPLAGAAGGPGIGRAAGRGIPAGVPMPQAPAGLAGPVRGVGGPSQQVM 142
           +GPP           AG AG  G     G   P G P      GL GP+    GP     
Sbjct: 743 QGPPGLQGMPGERGAAGIAGPKGDRGDVGEKGPEGAPGKDGGRGLTGPI----GPPGPAG 798

Query: 143 TPQGRGTVAAAAAAATASIAGAPTQYPPGRGGPPPPMGRGAPP----------------- 185
               +G V     A +A   GAP +   G  GPP P G   PP                 
Sbjct: 799 ANGEKGEVGPPGPAGSAGARGAPGE--RGETGPPGPAGFAGPPGADGQPGAKGEQGEAGQ 856

Query: 186 ------PGMMGP--PPGMRPPMG--PPMGIPPGRGTP--MGMPPPGMRPPPPGMRG 229
                 PG  GP   PG + P G   P G    +G P   G P    R  PPG  G
Sbjct: 857 KGDAGAPGPQGPSGAPGPQGPTGVTGPKGARGAQGPPGATGFPGAAGRVGPPGSNG 912



 Score = 51.2 bits (121), Expect = 7e-07
 Identities = 51/149 (34%), Positives = 60/149 (40%), Gaps = 13/149 (8%)

Query: 84   GPPPKDTGIARVPLAGAAGGPGIGRAAGRGIPAGVPMPQAPAGLAGPVRGVGGPSQQVMT 143
            GPP            G +G PG     G   PAG P  +   G  GP    G P  Q + 
Sbjct: 918  GPPGPSGKDGPKGARGDSGPPGRAGEPGLQGPAGPPGEKGEPGDDGPSGAEGPPGPQGLA 977

Query: 144  PQGRGTVAAAAAAATASIAGAP-TQYPPGRGGPPPPMG-RGAPPPGMMGPPPGMRPPMGP 201
             Q RG V            G P     PG+ G P   G RG  PPG +G PPG+  P G 
Sbjct: 978  GQ-RGIVGLPGQRGERGFPGLPGPSGEPGKQGAPGASGDRG--PPGPVG-PPGLTGPAG- 1032

Query: 202  PMGIPPGR-GTPMGMPPPGMRPPPPGMRG 229
                 PGR G+P    PPG R    G++G
Sbjct: 1033 ----EPGREGSPGADGPPG-RDGAAGVKG 1056



 Score = 50.8 bits (120), Expect = 1e-06
 Identities = 59/185 (31%), Positives = 68/185 (36%), Gaps = 49/185 (26%)

Query: 83   EGPPPKD-----------TGIARVPLA-GAAGGPG----IGRAAGRGIPAGVPMPQAPAG 126
            +GPP +D           TG    P A G  G PG     G+   RG  AG   P  P+G
Sbjct: 1043 DGPPGRDGAAGVKGDRGETGAVGAPGAPGPPGSPGPAGPTGKQGDRG-EAGAQGPMGPSG 1101

Query: 127  LAGPVRGVGGPSQ------QVMTPQGRGTVAAAAAAATASIAGAPTQYPPGRGGPPPPMG 180
             AG  RG+ GP        +   P  RG            + G P   P G  G   P G
Sbjct: 1102 PAG-ARGIQGPQGPRGDKGEAGEPGERGLKGHRGFTGLQGLPGPPG--PSGDQGASGPAG 1158

Query: 181  RGAP--PPGMMGPP--------PGMRPPMGP--------PMGIPPGRGTPMGMPPPGMRP 222
               P  PPG +GP         PG   P GP        P G P   G P    PPG  P
Sbjct: 1159 PSGPRGPPGPVGPSGKDGANGIPGPIGPPGPRGRSGETGPAGPPGNPGPP---GPPG--P 1213

Query: 223  PPPGM 227
            P PG+
Sbjct: 1214 PGPGI 1218



 Score = 49.7 bits (117), Expect = 2e-06
 Identities = 52/172 (30%), Positives = 56/172 (32%), Gaps = 43/172 (25%)

Query: 97  LAGAAGGPGIGRAAGRGIPAGVPMPQAPAGLAGPVRGVG--------------------- 135
           L G  G  G   AAG     G P P  P G  GP  G G                     
Sbjct: 328 LPGERGRTGPAGAAGARGNDGQPGPAGPPGPVGPAGGPGFPGAPGAKGEAGPTGARGPEG 387

Query: 136 --GPSQQVMTPQGRGTVAAA------------AAAATASIAGAPTQYPPGRGGPPPPMGR 181
             GP  +  TP   G   A+             +A    IAGAP    PG  GPP P G 
Sbjct: 388 AQGPRGEPGTPGSPGPAGASGNPGTDGIPGAKGSAGAPGIAGAPGF--PGPRGPPGPQGA 445

Query: 182 GAP--PPGMMGPP--PGMRPPMGPPMGIPPGRGTPMGMPPPGMRPPPPGMRG 229
             P  P G  G P   G +   GP     PG   P G P P       G RG
Sbjct: 446 TGPLGPKGQTGEPGIAGFKGEQGPKG--EPGPAGPQGAPGPAGEEGKRGARG 495



 Score = 49.7 bits (117), Expect = 2e-06
 Identities = 49/154 (31%), Positives = 57/154 (37%), Gaps = 41/154 (26%)

Query: 99  GAAGGPGIGRAAGRGIPAGVPMPQAPAGLAGPVRGVGGPSQQVMTPQGRGTVAAAAAAAT 158
           G  G PG+    G+    G   P  PAG AG                 RG   A   +  
Sbjct: 621 GLPGAPGLRGLPGKDGETGAAGPPGPAGPAGE----------------RGEQGAPGPSGF 664

Query: 159 ASIAGAPTQYPPGRGGPPPPMG--RGAPPPGMMGPP-----PGMRPPMGP-----PMGIP 206
             + G P   PPG GG P   G    A  PG++GP      PG R   G      P G+P
Sbjct: 665 QGLPGPPG--PPGEGGKPGDQGVPGEAGAPGLVGPRGERGFPGERGSPGAQGLQGPRGLP 722

Query: 207 --PGRGTPMGMP----PPGMRPPP-----PGMRG 229
             PG   P G      PPG + PP     PG RG
Sbjct: 723 GTPGTDGPKGASGPAGPPGAQGPPGLQGMPGERG 756



 Score = 48.9 bits (115), Expect = 4e-06
 Identities = 55/178 (30%), Positives = 62/178 (34%), Gaps = 33/178 (18%)

Query: 83   EGPPPKDTGIARVPLAGAAGGPGIGRAAGRGIPAGVPMPQAPAGLAGP--------VRGV 134
            EG P  D    R   AG  G  G   A G     G P    PAG  G          +G 
Sbjct: 1037 EGSPGADGPPGRDGAAGVKGDRGETGAVGAPGAPGPPGSPGPAGPTGKQGDRGEAGAQGP 1096

Query: 135  GGPS-----QQVMTPQG-RGTVAAAAAAATASIAG----APTQYPPGRGGPPPPMGRGAP 184
             GPS     + +  PQG RG    A       + G       Q  PG  GP    G   P
Sbjct: 1097 MGPSGPAGARGIQGPQGPRGDKGEAGEPGERGLKGHRGFTGLQGLPGPPGPSGDQGASGP 1156

Query: 185  --------PPGMMGP-----PPGMRPPMGPPMGIPPGRGTPMGMPPPGMRPPPPGMRG 229
                    PPG +GP       G+  P+GPP   P GR    G   P   P PPG  G
Sbjct: 1157 AGPSGPRGPPGPVGPSGKDGANGIPGPIGPPG--PRGRSGETGPAGPPGNPGPPGPPG 1212



 Score = 48.5 bits (114), Expect = 5e-06
 Identities = 50/164 (30%), Positives = 57/164 (34%), Gaps = 34/164 (20%)

Query: 99  GAAGGPGIGRAAGRGIPAGVPMPQAPAGLAGP--------------------VRGVGGPS 138
           GAAG PG    AG     G P P    GL GP                      G+ GP 
Sbjct: 639 GAAGPPGPAGPAGERGEQGAPGPSGFQGLPGPPGPPGEGGKPGDQGVPGEAGAPGLVGPR 698

Query: 139 QQVMTPQGRGTVAAAAAAATASIAGAP-TQYPPGRGGPPPPMGRGAPP-----PGMMGP- 191
            +   P  RG+  A        + G P T  P G  GP  P G   PP     PG  G  
Sbjct: 699 GERGFPGERGSPGAQGLQGPRGLPGTPGTDGPKGASGPAGPPGAQGPPGLQGMPGERGAA 758

Query: 192 ----PPGMRPPMGP--PMGIPPGRGTPMGMPPPGMRPPPPGMRG 229
               P G R  +G   P G  PG+    G+  P   P P G  G
Sbjct: 759 GIAGPKGDRGDVGEKGPEG-APGKDGGRGLTGPIGPPGPAGANG 801



 Score = 48.1 bits (113), Expect = 6e-06
 Identities = 59/187 (31%), Positives = 63/187 (33%), Gaps = 50/187 (26%)

Query: 92  IARVPLAGAAGGPGIGRAAGRGI-------PAGVPMPQAPAGLAGPVRGVGGPSQQVMTP 144
           I    LA A+G PG     G          P G P PQ PAG  GP RG  G   +   P
Sbjct: 88  ICPTDLATASGQPGPKGQKGEPGDIKDIVGPKGPPGPQGPAGEQGP-RGDRGDKGEKGAP 146

Query: 145 QGRGTVAAAAAAATASIAGAP-TQYPPGRG------------------------GPPPPM 179
             RG              G P    PPG G                        GP  PM
Sbjct: 147 GPRGRDGEPGTPGNPGPPGPPGPPGPPGLGGNFAAQMAGGFDEKAGGAQLGVMQGPMGPM 206

Query: 180 G-RGAP-------PPGMMGPP-----PGMRPPMGP--PMGIP--PGRGTPMGMPPPGMRP 222
           G RG P       P G  G P     PG+  PMGP  P G P  PG     G P      
Sbjct: 207 GPRGPPGPAGAPGPQGFQGNPGEPGEPGVSGPMGPRGPPGPPGKPGDDGEAGKPGKAGER 266

Query: 223 PPPGMRG 229
            PPG +G
Sbjct: 267 GPPGPQG 273



 Score = 48.1 bits (113), Expect = 6e-06
 Identities = 49/141 (34%), Positives = 54/141 (38%), Gaps = 34/141 (24%)

Query: 99  GAAGGPGIGRAAGRGIPAGVPMPQAPAGLAGPVRGVGGPSQQVMTPQGRGTVAAAAAAAT 158
           G AG PG+   +G     G P P  P GL G  RG  GP              A AA A 
Sbjct: 300 GEAGAPGVKGESGSPGENGSPGPMGPRGLPGE-RGRTGP--------------AGAAGAR 344

Query: 159 ASIAGAPTQYPPGRGGPPPPMGRGAPP-----PGMMGP--PPGMRPPMGP--PMGIPPGR 209
            +         PG  GPP P+G    P     PG  G   P G R P G   P G P   
Sbjct: 345 GN------DGQPGPAGPPGPVGPAGGPGFPGAPGAKGEAGPTGARGPEGAQGPRGEP--- 395

Query: 210 GTPMGMPPPGMRPPPPGMRGL 230
           GTP G P P      PG  G+
Sbjct: 396 GTP-GSPGPAGASGNPGTDGI 415



 Score = 46.2 bits (108), Expect = 2e-05
 Identities = 48/157 (30%), Positives = 59/157 (37%), Gaps = 27/157 (17%)

Query: 99  GAAGGPGIGRAAGRGIPAGVPMPQAPAGLAGPVRGVGGPSQQVMTPQGRGTVAAAAAAAT 158
           G  G PG     G+  P+G P      G  GP +G  G    +  P  +G       A  
Sbjct: 561 GLTGRPGDAGPQGKVGPSGAPGEDGRPGPPGP-QGARGQPGVMGFPGPKGANGEPGKAGE 619

Query: 159 ASIAGAP-------TQYPPGRGGPPPPMG-------RGAPPP----GMMGP--PPGMRPP 198
             + GAP            G  GPP P G       +GAP P    G+ GP  PPG    
Sbjct: 620 KGLPGAPGLRGLPGKDGETGAAGPPGPAGPAGERGEQGAPGPSGFQGLPGPPGPPGEGGK 679

Query: 199 MGPPMGIPPGRGTPMGMPPPGMRPPP-----PGMRGL 230
            G   G+P   G P  + P G R  P     PG +GL
Sbjct: 680 PG-DQGVPGEAGAPGLVGPRGERGFPGERGSPGAQGL 715



 Score = 45.8 bits (107), Expect = 3e-05
 Identities = 54/161 (33%), Positives = 61/161 (37%), Gaps = 20/161 (12%)

Query: 86  PPKDTGIARVPLAGA----AGGPGIGRAAGRGIPAGVPMPQAPAGLAGPVRGVGGPSQQ- 140
           PP   G     +AG     AGG  +G   G   P G   P  PAG  GP    G P +  
Sbjct: 172 PPGLGGNFAAQMAGGFDEKAGGAQLGVMQGPMGPMGPRGPPGPAGAPGPQGFQGNPGEPG 231

Query: 141 ---VMTPQG-RGTVAAAAAAATASIAGAPTQYPPGRGGPPPPMG-RGAP-PPGMMGPP-- 192
              V  P G RG             AG P +   G  GPP P G RG P  PG+ G    
Sbjct: 232 EPGVSGPMGPRGPPGPPGKPGDDGEAGKPGK--AGERGPPGPQGARGFPGTPGLPGVKGH 289

Query: 193 ---PGMRPPMGPPMGIPPGRGTPMGMPPPGMRPPPPGMRGL 230
              PG+    G   G P  +G   G P     P P G RGL
Sbjct: 290 RGYPGLDGAKG-EAGAPGVKG-ESGSPGENGSPGPMGPRGL 328



 Score = 38.5 bits (88), Expect = 0.005
 Identities = 54/183 (29%), Positives = 59/183 (32%), Gaps = 37/183 (20%)

Query: 83   EGPPPKDTGIARVPLAGAAGGPGIGRAAGRGIPAGVPMPQAPAGLAGPVRGVGGP----- 137
            EGPP       +  + G  G  G     G   P+G P  Q   G +G  RG  GP     
Sbjct: 968  EGPPGPQGLAGQRGIVGLPGQRGERGFPGLPGPSGEPGKQGAPGASGD-RGPPGPVGPPG 1026

Query: 138  ------------SQQVMTPQGR-GTVAAAAAAATASIAGAP-TQYPPGRGGPPPPMGR-- 181
                        S     P GR G              GAP    PPG  GP  P G+  
Sbjct: 1027 LTGPAGEPGREGSPGADGPPGRDGAAGVKGDRGETGAVGAPGAPGPPGSPGPAGPTGKQG 1086

Query: 182  ---GAPPPGMMGP--PPGMRPPMGP--PMGIPPGRGTPMGMPPPGMR--------PPPPG 226
                A   G MGP  P G R   GP  P G     G P      G R        P PPG
Sbjct: 1087 DRGEAGAQGPMGPSGPAGARGIQGPQGPRGDKGEAGEPGERGLKGHRGFTGLQGLPGPPG 1146

Query: 227  MRG 229
              G
Sbjct: 1147 PSG 1149



 Score = 38.5 bits (88), Expect = 0.005
 Identities = 34/107 (31%), Positives = 39/107 (36%), Gaps = 16/107 (14%)

Query: 97   LAGAAGGPGIGRAAGRGIPAGVPMPQAPAGLAGP-----VRGVGGPSQQVMTPQGRGTVA 151
            L G  G PG     G   PAG   P+ P G  GP       G+ GP   +  P  RG   
Sbjct: 1138 LQGLPGPPGPSGDQGASGPAGPSGPRGPPGPVGPSGKDGANGIPGP---IGPPGPRGR-- 1192

Query: 152  AAAAAATASIAGAPTQYPPGRGGPPPPMGRGAPPPGMMGPPPGMRPP 198
                +     AG P    PG  GPP P G G       G  P  + P
Sbjct: 1193 ----SGETGPAGPPGN--PGPPGPPGPPGPGIDMSAFAGLGPREKGP 1233



 Score = 37.0 bits (84), Expect = 0.014
 Identities = 50/159 (31%), Positives = 58/159 (36%), Gaps = 47/159 (29%)

Query: 82   VEGP--PPKDTGIARVP----LAGAAGGPGIGRAAGRGIPAGVPMPQAPAGLAGPVRGVG 135
            ++GP  P  D G A  P    L G  G  G+    G   P+G      PAG +GP RG  
Sbjct: 1108 IQGPQGPRGDKGEAGEPGERGLKGHRGFTGLQGLPGPPGPSGDQGASGPAGPSGP-RGPP 1166

Query: 136  GPSQQVMTPQGRGTVAAAAAAATASIAGAPTQYPPGRGGPPPPMGRGA------PPPGMM 189
            GP    + P G+                      PG  GPP P GR        PP    
Sbjct: 1167 GP----VGPSGKDGANGI----------------PGPIGPPGPRGRSGETGPAGPPGNP- 1205

Query: 190  GPPPGMRPPMGPPMGIPPGRGTPM----GMPPPGMRPPP 224
            GPP       GPP   PPG G  M    G+ P    P P
Sbjct: 1206 GPP-------GPPG--PPGPGIDMSAFAGLGPREKGPDP 1235


>gi|111118974 collagen, type II, alpha 1 isoform 2 precursor [Homo
           sapiens]
          Length = 1418

 Score = 65.1 bits (157), Expect = 5e-11
 Identities = 53/157 (33%), Positives = 60/157 (38%), Gaps = 26/157 (16%)

Query: 84  GPPPKDTGIARVPLAGAAGGPGIGRAAGRGIPAGVPMPQAPAGLAGP--VRGVGGPSQQV 141
           GPP  D         G AG  G   A G   P+G P PQ P G+ GP   RG  GP    
Sbjct: 768 GPPGADGQPGAKGEQGEAGQKGDAGAPGPQGPSGAPGPQGPTGVTGPKGARGAQGPPGAT 827

Query: 142 MTPQGRGTVAAAAAAATASIAGAPTQYPPGRGGPPPPMGRGAP--------PPGMMGPPP 193
             P   G V    +              PG  GPP P G+  P        PPG  G  P
Sbjct: 828 GFPGAAGRVGPPGSNGN-----------PGPPGPPGPSGKDGPKGARGDSGPPGRAG-EP 875

Query: 194 GMRPPMGPP-MGIPPGRGTPMGMPPPGMRPPPPGMRG 229
           G++ P GPP     PG   P G   P   P P G+ G
Sbjct: 876 GLQGPAGPPGEKGEPGDDGPSGAEGP---PGPQGLAG 909



 Score = 57.4 bits (137), Expect = 1e-08
 Identities = 51/158 (32%), Positives = 55/158 (34%), Gaps = 13/158 (8%)

Query: 84  GPPPKDTGIARVPLAGAAGGPGIGRAAGRGIPAGVPMPQAPAGLAGPVRGVGGPSQQVMT 143
           GPP        +   G  G PGI    G   P G P P  P G  GP  G  G       
Sbjct: 369 GPPGPQGATGPLGPKGQTGEPGIAGFKGEQGPKGEPGPAGPQGAPGPA-GEEGKRGARGE 427

Query: 144 PQGRGTVAAAAAAATASIAGAPTQ----YPPGRGGPPPPMGRGAP-----PPGMMGPP-- 192
           P G G +            G P Q     P G  G   P G   P      PG  G P  
Sbjct: 428 PGGVGPIGPPGERGAPGNRGFPGQDGLAGPKGAPGERGPSGLAGPKGANGDPGRPGEPGL 487

Query: 193 PGMRPPMGPPMGI-PPGRGTPMGMPPPGMRPPPPGMRG 229
           PG R   G P    P G+  P G P    RP PPG +G
Sbjct: 488 PGARGLTGRPGDAGPQGKVGPSGAPGEDGRPGPPGPQG 525



 Score = 55.8 bits (133), Expect = 3e-08
 Identities = 58/173 (33%), Positives = 60/173 (34%), Gaps = 41/173 (23%)

Query: 83  EGPPPKDTGIARVPLAGAAGGPG----------------IGRAAGRGIPA--GVPMPQAP 124
           EG P KD G     L G  G PG                 G A  RG P   G   P  P
Sbjct: 707 EGAPGKDGGRG---LTGPIGPPGPAGANGEKGEVGPPGPAGSAGARGAPGERGETGPPGP 763

Query: 125 AGLAGPVRGVGGPSQQVMTPQGRGTVAAAAAAATASIAGAP-TQYPPGRGGPPPPMGRGA 183
           AG AGP    G P          G       A     AGAP  Q P G  GP  P G   
Sbjct: 764 AGFAGPPGADGQP----------GAKGEQGEAGQKGDAGAPGPQGPSGAPGPQGPTGVTG 813

Query: 184 P--PPGMMGPP-----PGMRPPMGPPMGIPPGRGTPMGMPPPGMRPPPPGMRG 229
           P    G  GPP     PG    +GPP     G   P G P P  +  P G RG
Sbjct: 814 PKGARGAQGPPGATGFPGAAGRVGPPGS--NGNPGPPGPPGPSGKDGPKGARG 864



 Score = 52.8 bits (125), Expect = 3e-07
 Identities = 55/157 (35%), Positives = 62/157 (39%), Gaps = 26/157 (16%)

Query: 84   GPPPKDTGIARVP-LAGAAGGPGIGRAAGRGIPAGVPMPQAPAGLAGPVRGVGGPSQQVM 142
            GPP    G A  P L G AG PG     G   P+G   P  P GLAG    VG P Q+  
Sbjct: 867  GPP----GRAGEPGLQGPAGPPGEKGEPGDDGPSGAEGPPGPQGLAGQRGIVGLPGQR-- 920

Query: 143  TPQGRGTVAAAAAAATASIAGAPTQYPPGRGGPPPPMGRGAPPPGMMGP--------PPG 194
                RG       +      GAP     G  GPP P+G    PPG+ GP         PG
Sbjct: 921  --GERGFPGLPGPSGEPGKQGAPG--ASGDRGPPGPVG----PPGLTGPAGEPGREGSPG 972

Query: 195  MRPPMG--PPMGIPPGRGTPMGMPPPGMRPPPPGMRG 229
               P G     G+   RG    +  PG  P PPG  G
Sbjct: 973  ADGPPGRDGAAGVKGDRGETGAVGAPG-APGPPGSPG 1008



 Score = 52.4 bits (124), Expect = 3e-07
 Identities = 52/176 (29%), Positives = 59/176 (33%), Gaps = 35/176 (19%)

Query: 83  EGPPPKDTGIARVPLAGAAGGPGIGRAAGRGIPAGVPMPQAPAGLAGPVRGVGGPSQQVM 142
           +GPP           AG AG  G     G   P G P      GL GP+    GP     
Sbjct: 674 QGPPGLQGMPGERGAAGIAGPKGDRGDVGEKGPEGAPGKDGGRGLTGPI----GPPGPAG 729

Query: 143 TPQGRGTVAAAAAAATASIAGAPTQYPPGRGGPPPPMGRGAPP----------------- 185
               +G V     A +A   GAP +   G  GPP P G   PP                 
Sbjct: 730 ANGEKGEVGPPGPAGSAGARGAPGE--RGETGPPGPAGFAGPPGADGQPGAKGEQGEAGQ 787

Query: 186 ------PGMMGP--PPGMRPPMG--PPMGIPPGRGTP--MGMPPPGMRPPPPGMRG 229
                 PG  GP   PG + P G   P G    +G P   G P    R  PPG  G
Sbjct: 788 KGDAGAPGPQGPSGAPGPQGPTGVTGPKGARGAQGPPGATGFPGAAGRVGPPGSNG 843



 Score = 51.2 bits (121), Expect = 7e-07
 Identities = 51/149 (34%), Positives = 60/149 (40%), Gaps = 13/149 (8%)

Query: 84  GPPPKDTGIARVPLAGAAGGPGIGRAAGRGIPAGVPMPQAPAGLAGPVRGVGGPSQQVMT 143
           GPP            G +G PG     G   PAG P  +   G  GP    G P  Q + 
Sbjct: 849 GPPGPSGKDGPKGARGDSGPPGRAGEPGLQGPAGPPGEKGEPGDDGPSGAEGPPGPQGLA 908

Query: 144 PQGRGTVAAAAAAATASIAGAP-TQYPPGRGGPPPPMG-RGAPPPGMMGPPPGMRPPMGP 201
            Q RG V            G P     PG+ G P   G RG  PPG +G PPG+  P G 
Sbjct: 909 GQ-RGIVGLPGQRGERGFPGLPGPSGEPGKQGAPGASGDRG--PPGPVG-PPGLTGPAG- 963

Query: 202 PMGIPPGR-GTPMGMPPPGMRPPPPGMRG 229
                PGR G+P    PPG R    G++G
Sbjct: 964 ----EPGREGSPGADGPPG-RDGAAGVKG 987



 Score = 50.8 bits (120), Expect = 1e-06
 Identities = 59/185 (31%), Positives = 68/185 (36%), Gaps = 49/185 (26%)

Query: 83   EGPPPKD-----------TGIARVPLA-GAAGGPG----IGRAAGRGIPAGVPMPQAPAG 126
            +GPP +D           TG    P A G  G PG     G+   RG  AG   P  P+G
Sbjct: 974  DGPPGRDGAAGVKGDRGETGAVGAPGAPGPPGSPGPAGPTGKQGDRG-EAGAQGPMGPSG 1032

Query: 127  LAGPVRGVGGPSQ------QVMTPQGRGTVAAAAAAATASIAGAPTQYPPGRGGPPPPMG 180
             AG  RG+ GP        +   P  RG            + G P   P G  G   P G
Sbjct: 1033 PAG-ARGIQGPQGPRGDKGEAGEPGERGLKGHRGFTGLQGLPGPPG--PSGDQGASGPAG 1089

Query: 181  RGAP--PPGMMGPP--------PGMRPPMGP--------PMGIPPGRGTPMGMPPPGMRP 222
               P  PPG +GP         PG   P GP        P G P   G P    PPG  P
Sbjct: 1090 PSGPRGPPGPVGPSGKDGANGIPGPIGPPGPRGRSGETGPAGPPGNPGPP---GPPG--P 1144

Query: 223  PPPGM 227
            P PG+
Sbjct: 1145 PGPGI 1149



 Score = 49.7 bits (117), Expect = 2e-06
 Identities = 52/172 (30%), Positives = 56/172 (32%), Gaps = 43/172 (25%)

Query: 97  LAGAAGGPGIGRAAGRGIPAGVPMPQAPAGLAGPVRGVG--------------------- 135
           L G  G  G   AAG     G P P  P G  GP  G G                     
Sbjct: 259 LPGERGRTGPAGAAGARGNDGQPGPAGPPGPVGPAGGPGFPGAPGAKGEAGPTGARGPEG 318

Query: 136 --GPSQQVMTPQGRGTVAAA------------AAAATASIAGAPTQYPPGRGGPPPPMGR 181
             GP  +  TP   G   A+             +A    IAGAP    PG  GPP P G 
Sbjct: 319 AQGPRGEPGTPGSPGPAGASGNPGTDGIPGAKGSAGAPGIAGAPGF--PGPRGPPGPQGA 376

Query: 182 GAP--PPGMMGPP--PGMRPPMGPPMGIPPGRGTPMGMPPPGMRPPPPGMRG 229
             P  P G  G P   G +   GP     PG   P G P P       G RG
Sbjct: 377 TGPLGPKGQTGEPGIAGFKGEQGPKG--EPGPAGPQGAPGPAGEEGKRGARG 426



 Score = 49.7 bits (117), Expect = 2e-06
 Identities = 49/154 (31%), Positives = 57/154 (37%), Gaps = 41/154 (26%)

Query: 99  GAAGGPGIGRAAGRGIPAGVPMPQAPAGLAGPVRGVGGPSQQVMTPQGRGTVAAAAAAAT 158
           G  G PG+    G+    G   P  PAG AG                 RG   A   +  
Sbjct: 552 GLPGAPGLRGLPGKDGETGAAGPPGPAGPAGE----------------RGEQGAPGPSGF 595

Query: 159 ASIAGAPTQYPPGRGGPPPPMG--RGAPPPGMMGPP-----PGMRPPMGP-----PMGIP 206
             + G P   PPG GG P   G    A  PG++GP      PG R   G      P G+P
Sbjct: 596 QGLPGPPG--PPGEGGKPGDQGVPGEAGAPGLVGPRGERGFPGERGSPGAQGLQGPRGLP 653

Query: 207 --PGRGTPMGMP----PPGMRPPP-----PGMRG 229
             PG   P G      PPG + PP     PG RG
Sbjct: 654 GTPGTDGPKGASGPAGPPGAQGPPGLQGMPGERG 687



 Score = 48.9 bits (115), Expect = 4e-06
 Identities = 55/178 (30%), Positives = 62/178 (34%), Gaps = 33/178 (18%)

Query: 83   EGPPPKDTGIARVPLAGAAGGPGIGRAAGRGIPAGVPMPQAPAGLAGP--------VRGV 134
            EG P  D    R   AG  G  G   A G     G P    PAG  G          +G 
Sbjct: 968  EGSPGADGPPGRDGAAGVKGDRGETGAVGAPGAPGPPGSPGPAGPTGKQGDRGEAGAQGP 1027

Query: 135  GGPS-----QQVMTPQG-RGTVAAAAAAATASIAG----APTQYPPGRGGPPPPMGRGAP 184
             GPS     + +  PQG RG    A       + G       Q  PG  GP    G   P
Sbjct: 1028 MGPSGPAGARGIQGPQGPRGDKGEAGEPGERGLKGHRGFTGLQGLPGPPGPSGDQGASGP 1087

Query: 185  --------PPGMMGP-----PPGMRPPMGPPMGIPPGRGTPMGMPPPGMRPPPPGMRG 229
                    PPG +GP       G+  P+GPP   P GR    G   P   P PPG  G
Sbjct: 1088 AGPSGPRGPPGPVGPSGKDGANGIPGPIGPPG--PRGRSGETGPAGPPGNPGPPGPPG 1143



 Score = 48.5 bits (114), Expect = 5e-06
 Identities = 50/164 (30%), Positives = 57/164 (34%), Gaps = 34/164 (20%)

Query: 99  GAAGGPGIGRAAGRGIPAGVPMPQAPAGLAGP--------------------VRGVGGPS 138
           GAAG PG    AG     G P P    GL GP                      G+ GP 
Sbjct: 570 GAAGPPGPAGPAGERGEQGAPGPSGFQGLPGPPGPPGEGGKPGDQGVPGEAGAPGLVGPR 629

Query: 139 QQVMTPQGRGTVAAAAAAATASIAGAP-TQYPPGRGGPPPPMGRGAPP-----PGMMGP- 191
            +   P  RG+  A        + G P T  P G  GP  P G   PP     PG  G  
Sbjct: 630 GERGFPGERGSPGAQGLQGPRGLPGTPGTDGPKGASGPAGPPGAQGPPGLQGMPGERGAA 689

Query: 192 ----PPGMRPPMGP--PMGIPPGRGTPMGMPPPGMRPPPPGMRG 229
               P G R  +G   P G  PG+    G+  P   P P G  G
Sbjct: 690 GIAGPKGDRGDVGEKGPEG-APGKDGGRGLTGPIGPPGPAGANG 732



 Score = 48.1 bits (113), Expect = 6e-06
 Identities = 49/141 (34%), Positives = 54/141 (38%), Gaps = 34/141 (24%)

Query: 99  GAAGGPGIGRAAGRGIPAGVPMPQAPAGLAGPVRGVGGPSQQVMTPQGRGTVAAAAAAAT 158
           G AG PG+   +G     G P P  P GL G  RG  GP              A AA A 
Sbjct: 231 GEAGAPGVKGESGSPGENGSPGPMGPRGLPGE-RGRTGP--------------AGAAGAR 275

Query: 159 ASIAGAPTQYPPGRGGPPPPMGRGAPP-----PGMMGP--PPGMRPPMGP--PMGIPPGR 209
            +         PG  GPP P+G    P     PG  G   P G R P G   P G P   
Sbjct: 276 GN------DGQPGPAGPPGPVGPAGGPGFPGAPGAKGEAGPTGARGPEGAQGPRGEP--- 326

Query: 210 GTPMGMPPPGMRPPPPGMRGL 230
           GTP G P P      PG  G+
Sbjct: 327 GTP-GSPGPAGASGNPGTDGI 346



 Score = 47.4 bits (111), Expect = 1e-05
 Identities = 51/157 (32%), Positives = 54/157 (34%), Gaps = 43/157 (27%)

Query: 115 PAGVPMPQAPAGLAGPVRGVGGPSQQVMTPQGRGTVAAAAAAATASIAGAP-TQYPPGRG 173
           P G P PQ PAG  GP RG  G   +   P  RG              G P    PPG G
Sbjct: 49  PKGPPGPQGPAGEQGP-RGDRGDKGEKGAPGPRGRDGEPGTPGNPGPPGPPGPPGPPGLG 107

Query: 174 ------------------------GPPPPMG-RGAP-------PPGMMGPP-----PGMR 196
                                   GP  PMG RG P       P G  G P     PG+ 
Sbjct: 108 GNFAAQMAGGFDEKAGGAQLGVMQGPMGPMGPRGPPGPAGAPGPQGFQGNPGEPGEPGVS 167

Query: 197 PPMGP--PMGIP--PGRGTPMGMPPPGMRPPPPGMRG 229
            PMGP  P G P  PG     G P       PPG +G
Sbjct: 168 GPMGPRGPPGPPGKPGDDGEAGKPGKAGERGPPGPQG 204



 Score = 46.2 bits (108), Expect = 2e-05
 Identities = 48/157 (30%), Positives = 59/157 (37%), Gaps = 27/157 (17%)

Query: 99  GAAGGPGIGRAAGRGIPAGVPMPQAPAGLAGPVRGVGGPSQQVMTPQGRGTVAAAAAAAT 158
           G  G PG     G+  P+G P      G  GP +G  G    +  P  +G       A  
Sbjct: 492 GLTGRPGDAGPQGKVGPSGAPGEDGRPGPPGP-QGARGQPGVMGFPGPKGANGEPGKAGE 550

Query: 159 ASIAGAP-------TQYPPGRGGPPPPMG-------RGAPPP----GMMGP--PPGMRPP 198
             + GAP            G  GPP P G       +GAP P    G+ GP  PPG    
Sbjct: 551 KGLPGAPGLRGLPGKDGETGAAGPPGPAGPAGERGEQGAPGPSGFQGLPGPPGPPGEGGK 610

Query: 199 MGPPMGIPPGRGTPMGMPPPGMRPPP-----PGMRGL 230
            G   G+P   G P  + P G R  P     PG +GL
Sbjct: 611 PG-DQGVPGEAGAPGLVGPRGERGFPGERGSPGAQGL 646



 Score = 45.8 bits (107), Expect = 3e-05
 Identities = 54/161 (33%), Positives = 61/161 (37%), Gaps = 20/161 (12%)

Query: 86  PPKDTGIARVPLAGA----AGGPGIGRAAGRGIPAGVPMPQAPAGLAGPVRGVGGPSQQ- 140
           PP   G     +AG     AGG  +G   G   P G   P  PAG  GP    G P +  
Sbjct: 103 PPGLGGNFAAQMAGGFDEKAGGAQLGVMQGPMGPMGPRGPPGPAGAPGPQGFQGNPGEPG 162

Query: 141 ---VMTPQG-RGTVAAAAAAATASIAGAPTQYPPGRGGPPPPMG-RGAP-PPGMMGPP-- 192
              V  P G RG             AG P +   G  GPP P G RG P  PG+ G    
Sbjct: 163 EPGVSGPMGPRGPPGPPGKPGDDGEAGKPGK--AGERGPPGPQGARGFPGTPGLPGVKGH 220

Query: 193 ---PGMRPPMGPPMGIPPGRGTPMGMPPPGMRPPPPGMRGL 230
              PG+    G   G P  +G   G P     P P G RGL
Sbjct: 221 RGYPGLDGAKG-EAGAPGVKG-ESGSPGENGSPGPMGPRGL 259



 Score = 38.5 bits (88), Expect = 0.005
 Identities = 54/183 (29%), Positives = 59/183 (32%), Gaps = 37/183 (20%)

Query: 83   EGPPPKDTGIARVPLAGAAGGPGIGRAAGRGIPAGVPMPQAPAGLAGPVRGVGGP----- 137
            EGPP       +  + G  G  G     G   P+G P  Q   G +G  RG  GP     
Sbjct: 899  EGPPGPQGLAGQRGIVGLPGQRGERGFPGLPGPSGEPGKQGAPGASGD-RGPPGPVGPPG 957

Query: 138  ------------SQQVMTPQGR-GTVAAAAAAATASIAGAP-TQYPPGRGGPPPPMGR-- 181
                        S     P GR G              GAP    PPG  GP  P G+  
Sbjct: 958  LTGPAGEPGREGSPGADGPPGRDGAAGVKGDRGETGAVGAPGAPGPPGSPGPAGPTGKQG 1017

Query: 182  ---GAPPPGMMGP--PPGMRPPMGP--PMGIPPGRGTPMGMPPPGMR--------PPPPG 226
                A   G MGP  P G R   GP  P G     G P      G R        P PPG
Sbjct: 1018 DRGEAGAQGPMGPSGPAGARGIQGPQGPRGDKGEAGEPGERGLKGHRGFTGLQGLPGPPG 1077

Query: 227  MRG 229
              G
Sbjct: 1078 PSG 1080



 Score = 38.5 bits (88), Expect = 0.005
 Identities = 34/107 (31%), Positives = 39/107 (36%), Gaps = 16/107 (14%)

Query: 97   LAGAAGGPGIGRAAGRGIPAGVPMPQAPAGLAGP-----VRGVGGPSQQVMTPQGRGTVA 151
            L G  G PG     G   PAG   P+ P G  GP       G+ GP   +  P  RG   
Sbjct: 1069 LQGLPGPPGPSGDQGASGPAGPSGPRGPPGPVGPSGKDGANGIPGP---IGPPGPRGR-- 1123

Query: 152  AAAAAATASIAGAPTQYPPGRGGPPPPMGRGAPPPGMMGPPPGMRPP 198
                +     AG P    PG  GPP P G G       G  P  + P
Sbjct: 1124 ----SGETGPAGPPGN--PGPPGPPGPPGPGIDMSAFAGLGPREKGP 1164



 Score = 37.0 bits (84), Expect = 0.014
 Identities = 50/159 (31%), Positives = 58/159 (36%), Gaps = 47/159 (29%)

Query: 82   VEGP--PPKDTGIARVP----LAGAAGGPGIGRAAGRGIPAGVPMPQAPAGLAGPVRGVG 135
            ++GP  P  D G A  P    L G  G  G+    G   P+G      PAG +GP RG  
Sbjct: 1039 IQGPQGPRGDKGEAGEPGERGLKGHRGFTGLQGLPGPPGPSGDQGASGPAGPSGP-RGPP 1097

Query: 136  GPSQQVMTPQGRGTVAAAAAAATASIAGAPTQYPPGRGGPPPPMGRGA------PPPGMM 189
            GP    + P G+                      PG  GPP P GR        PP    
Sbjct: 1098 GP----VGPSGKDGANGI----------------PGPIGPPGPRGRSGETGPAGPPGNP- 1136

Query: 190  GPPPGMRPPMGPPMGIPPGRGTPM----GMPPPGMRPPP 224
            GPP       GPP   PPG G  M    G+ P    P P
Sbjct: 1137 GPP-------GPPG--PPGPGIDMSAFAGLGPREKGPDP 1166


>gi|89276751 alpha 1 type V collagen preproprotein [Homo sapiens]
          Length = 1838

 Score = 65.1 bits (157), Expect = 5e-11
 Identities = 57/164 (34%), Positives = 65/164 (39%), Gaps = 29/164 (17%)

Query: 83   EGP-----PPKDTGIARVPLAGAAGGPGIGRAAGRGIPAGVPMPQAPAGLAGPVRGVGGP 137
            EGP     PP   G+  +P  G  G  G     G+  P G P P+ P+G  G   G  GP
Sbjct: 1215 EGPRGFPGPPGPVGLQGLP--GPPGEKGETGDVGQMGPPGPPGPRGPSGAPG-ADGPQGP 1271

Query: 138  SQQVMTPQGRGTVAAAAAAATASIAGAPTQYPPGRGGPPPPMGR-----------GAPPP 186
                  P G G   A         AG P    PG GGPP P G             A PP
Sbjct: 1272 ------PGGIGNPGAVGEKGEPGEAGEPGL--PGEGGPPGPKGERGEKGESGPSGAAGPP 1323

Query: 187  GMMGPPPGMRPPMGP-PMGIPPGRGTPMGMPPPGMRPPPPGMRG 229
            G  GPP    P   P P+G P   G P G P P  +  PPG +G
Sbjct: 1324 GPKGPPGDDGPKGSPGPVGFPGDPGPP-GEPGPAGQDGPPGDKG 1366



 Score = 55.5 bits (132), Expect = 4e-08
 Identities = 50/157 (31%), Positives = 61/157 (38%), Gaps = 21/157 (13%)

Query: 83   EGPPPKDTGIARVPLAGAAGGPGIGRAAGRGIPAGVPMPQAPAGLAGPVR--------GV 134
            EG PP   G       G  G  G   AAG   P G P    P G  GPV         G 
Sbjct: 1298 EGGPPGPKGER-----GEKGESGPSGAAGPPGPKGPPGDDGPKGSPGPVGFPGDPGPPGE 1352

Query: 135  GGPSQQVMTPQGRGTVAAAAAAATASIAGAP-TQYPPGRGGPPPPMGRGAPPPGMMGPPP 193
             GP+ Q   P  +G         +    G P    PPG+ GPP P G    P G  G   
Sbjct: 1353 PGPAGQDGPPGDKGDDGEPGQTGSPGPTGEPGPSGPPGKRGPPGPAG----PEGRQGEK- 1407

Query: 194  GMRPPMGPPMGIPPGRGTPMGMPPPGMRPPPPGMRGL 230
            G +   G  +  PPG+  P+G      +P P G+RG+
Sbjct: 1408 GAKGEAG--LEGPPGKTGPIGPQGAPGKPGPDGLRGI 1442



 Score = 52.4 bits (124), Expect = 3e-07
 Identities = 67/186 (36%), Positives = 74/186 (39%), Gaps = 43/186 (23%)

Query: 83   EGPP----PKDTGIARVPLAGAAGGPGI-GRAAGRGIPA--------GVPMPQAPAG--- 126
            EGPP    P  +   R P AGAAG  GI GR   +G P         G   PQ PAG   
Sbjct: 1077 EGPPGPPGPAGSPGERGP-AGAAGPIGIPGRPGPQGPPGPAGEKGAPGEKGPQGPAGRDG 1135

Query: 127  LAGPVRGVGGPSQQVMTPQGRGTVAAAAAAATASIAGAP-TQYPPGRGGPPPPMGRGAPP 185
            L GPV G+ GP+  V  P   G              G    Q PPG  GP  P+G+  P 
Sbjct: 1136 LQGPV-GLPGPAGPVGPPGEDGDKGEIGEPGQKGSKGDKGEQGPPGPTGPQGPIGQ--PG 1192

Query: 186  PGMMGPPPGMRPPMG--------PPMGI--PPGRGTPMGMP-PPG----------MRPP- 223
            P      PG R   G         P G   PPG     G+P PPG          M PP 
Sbjct: 1193 PSGADGEPGPRGQQGLFGQKGDEGPRGFPGPPGPVGLQGLPGPPGEKGETGDVGQMGPPG 1252

Query: 224  PPGMRG 229
            PPG RG
Sbjct: 1253 PPGPRG 1258



 Score = 52.4 bits (124), Expect = 3e-07
 Identities = 50/160 (31%), Positives = 60/160 (37%), Gaps = 19/160 (11%)

Query: 82   VEGPPPKDTGIARVPLAGAAGGPGI----GRAAGRGIPA-----GVPMPQAPAGLAGPVR 132
            +EGPP K   I      G  G  G+    G    +G+P      G P P  P GL G ++
Sbjct: 1415 LEGPPGKTGPIGPQGAPGKPGPDGLRGIPGPVGEQGLPGSPGPDGPPGPMGPPGLPG-LK 1473

Query: 133  GVGGPSQQVMTPQGRGTVAAAAAAATASIAGAPTQYPPGRGGPPPPMGRGAPPPGMMGP- 191
            G  GP  +   P   G +            G P   P G  GP    G    P G +GP 
Sbjct: 1474 GDSGPKGEKGHPGLIGLIGPPGEQGEKGDRGLPG--PQGSSGPKGEQGI-TGPSGPIGPP 1530

Query: 192  -PPGMRPPMGPP----MGIPPGRGTPMGMPPPGMRPPPPG 226
             PPG+  P GP        P G     G P P   P PPG
Sbjct: 1531 GPPGLPGPPGPKGAKGSSGPTGPKGEAGHPGPPGPPGPPG 1570



 Score = 52.0 bits (123), Expect = 4e-07
 Identities = 54/156 (34%), Positives = 61/156 (39%), Gaps = 16/156 (10%)

Query: 84  GPPPKDTGIARVPLAGAAGGPGIGRAAGRGIPAGVPMPQAPAGLAGPVRGVGGPSQQVMT 143
           GPP  D         G  G PG     G   P G P P  P G+ G + G  GP   V  
Sbjct: 655 GPPGDDGERGDDGEVGPRGLPGEPGPRGLLGPKGPPGPPGPPGVTG-MDGQPGPKGNV-G 712

Query: 144 PQGR-GTVAAAAAAATASIAGAPTQYPPGRGGPPP---PMGRGAPP--PGMMGPP--PGM 195
           PQG  G            + G     P G  GPP    P+G+   P  PG  GPP  PG 
Sbjct: 713 PQGEPGPPGQQGNPGAQGLPG-----PQGAIGPPGEKGPLGKPGLPGMPGADGPPGHPGK 767

Query: 196 RPPMGPPMGI-PPGRGTPMGMPPPGMRPPPPGMRGL 230
             P G   G  PPG   P+G P P       G+RGL
Sbjct: 768 EGPPGEKGGQGPPGPQGPIGYPGPRGVKGADGIRGL 803



 Score = 52.0 bits (123), Expect = 4e-07
 Identities = 52/162 (32%), Positives = 62/162 (38%), Gaps = 22/162 (13%)

Query: 83   EGPP-----PKDTGIARVPLAGAAGGPGIGRAAGRGIPAGVPMPQAPAGLAGPV------ 131
            +GPP     P D G+      GA G  G     G   PAG P  + PAG AGP+      
Sbjct: 1050 DGPPGLRGFPGDRGLPGP--VGALGLKGNEGPPGPPGPAGSPGERGPAGAAGPIGIPGRP 1107

Query: 132  --RGVGGPSQQVMTPQGRGTVAAAAAAATASIAGAPTQYPPGRGGPPPPMGRGAP--PPG 187
              +G  GP+ +   P  +G    A         G P   P G  GPP   G       PG
Sbjct: 1108 GPQGPPGPAGEKGAPGEKGPQGPAGRDGLQGPVGLPG--PAGPVGPPGEDGDKGEIGEPG 1165

Query: 188  MMGPPPGMRPPMGPPMGIPPGRGTPMGMPPPGMRPPPPGMRG 229
              G   G +   GPP   P G   P+G P P      PG RG
Sbjct: 1166 QKG-SKGDKGEQGPPG--PTGPQGPIGQPGPSGADGEPGPRG 1204



 Score = 51.6 bits (122), Expect = 6e-07
 Identities = 58/179 (32%), Positives = 68/179 (37%), Gaps = 49/179 (27%)

Query: 93  ARVPLAGAAGGPGIGRAAGRGIPAGVPMPQAPAGLAGPV-----RGVGGPSQQVMTPQGR 147
           AR+ L G AG  G+    GR  P G P      G  G V     RGV GP      P  R
Sbjct: 553 ARLALRGPAGPMGL---TGRPGPVGPPGSGGLKGEPGDVGPQGPRGVQGPPGPAGKPGRR 609

Query: 148 GTVAAAAAAATAS------------IAGAPTQY----PPGRGGPPPPMG----------- 180
           G   +  A                 +AG P +      PG  GPP P G           
Sbjct: 610 GRAGSDGARGMPGQTGPKGDRGFDGLAGLPGEKGHRGDPGPSGPPGPPGDDGERGDDGEV 669

Query: 181 --RGAP----PPGMMGP--PPGMRPPMGPPMGIP--PGRGTPMGMPPPGMRPPPPGMRG 229
             RG P    P G++GP  PPG   P GPP G+    G+  P G   P   P PPG +G
Sbjct: 670 GPRGLPGEPGPRGLLGPKGPPG---PPGPP-GVTGMDGQPGPKGNVGPQGEPGPPGQQG 724



 Score = 51.2 bits (121), Expect = 7e-07
 Identities = 49/145 (33%), Positives = 55/145 (37%), Gaps = 32/145 (22%)

Query: 86   PPKDTGIARVPLAGAAGGPGIGRAAGRGIPAGVPMPQAPAGLAGPVRGVGGPSQQVMTPQ 145
            PP D G    P  G  G PG         P G P P  P G  GP  G  GP        
Sbjct: 1361 PPGDKGDDGEP--GQTGSPG---------PTGEPGPSGPPGKRGP-PGPAGP-------- 1400

Query: 146  GRGTVAAAAAAATASIAGAPTQYPPGRGGPPPPMGR-GAPPPGMMGPPPGMRPPMGPPMG 204
              G      A   A + G     PPG+ GP  P G  G P P  +   PG     G P G
Sbjct: 1401 -EGRQGEKGAKGEAGLEG-----PPGKTGPIGPQGAPGKPGPDGLRGIPGPVGEQGLP-G 1453

Query: 205  IPPGRGTPMGMPPPGMRPPPPGMRG 229
             P   G P  M PPG+    PG++G
Sbjct: 1454 SPGPDGPPGPMGPPGL----PGLKG 1474



 Score = 49.7 bits (117), Expect = 2e-06
 Identities = 50/145 (34%), Positives = 62/145 (42%), Gaps = 24/145 (16%)

Query: 86   PPKDTGIARVP-LAGAAGGPGIGRAAGRGIPAGVPMPQAPAGLAGPVRGVG--------G 136
            PP + G+  +    G  G PG     G+  P G+       GL GPV  +G        G
Sbjct: 1022 PPGEQGLPGLAGKEGTKGDPGPAGLPGKDGPPGLRGFPGDRGLPGPVGALGLKGNEGPPG 1081

Query: 137  PSQQVMTPQGRGTVAAAAAAATASIAGAPTQYPPGRGGPPPPMG-RGAPPPGMMGPP-PG 194
            P     +P  RG    A AA    I G      PG  GPP P G +GA  PG  GP  P 
Sbjct: 1082 PPGPAGSPGERG---PAGAAGPIGIPGR-----PGPQGPPGPAGEKGA--PGEKGPQGPA 1131

Query: 195  MRPPMGPPMGIPPGRGTPMGMPPPG 219
             R  +  P+G+ PG   P+G  PPG
Sbjct: 1132 GRDGLQGPVGL-PGPAGPVG--PPG 1153



 Score = 48.1 bits (113), Expect = 6e-06
 Identities = 55/196 (28%), Positives = 64/196 (32%), Gaps = 51/196 (26%)

Query: 83  EGPPPKDTGIARVPLAGAAGGPGIGRAAGRGIPAGVPMPQAPAGLAGPVRGVGGPSQQVM 142
           +G P     I      G  G PG+    G   P G P  + P G  G  +G  GP   + 
Sbjct: 729 QGLPGPQGAIGPPGEKGPLGKPGLPGMPGADGPPGHPGKEGPPGEKGG-QGPPGPQGPIG 787

Query: 143 TPQGRGTVAAAAAAATASIAGAPTQ----------------------YPPGRGGPPPPMG 180
            P  RG   A          G   +                       P G  GP  P G
Sbjct: 788 YPGPRGVKGADGIRGLKGTKGEKGEDGFPGFKGDMGIKGDRGEIGPPGPRGEDGPEGPKG 847

Query: 181 RGAP--PPGMMGPP--------------PGMRPPMGPPMGIP---------PGRGTPMGM 215
           RG P   PG +GPP              PG + P G  +G P          GRGTP   
Sbjct: 848 RGGPNGDPGPLGPPGEKGKLGVPGLPGYPGRQGPKG-SIGFPGFPGANGEKGGRGTPGKP 906

Query: 216 PPPGMRPP--PPGMRG 229
            P G R P  P G RG
Sbjct: 907 GPRGQRGPTGPRGERG 922



 Score = 47.4 bits (111), Expect = 1e-05
 Identities = 45/145 (31%), Positives = 48/145 (33%), Gaps = 18/145 (12%)

Query: 99  GAAGGPGIGRAAGRGIPAGVPMPQAPAGLAGPVRGVG--------GPSQQVMTPQGRGTV 150
           G  G  G     GRG P G P P  P G  G +   G        GP   +  P   G  
Sbjct: 835 GPRGEDGPEGPKGRGGPNGDPGPLGPPGEKGKLGVPGLPGYPGRQGPKGSIGFPGFPGAN 894

Query: 151 AAAAAAATASIAGAPTQYPPGRGGPPPPMGRGAP-----PPGMMGPPPGMRPPMGPPMGI 205
                  T    G     P G+ GP  P G   P      PG  G   G  P   P    
Sbjct: 895 GEKGGRGTPGKPG-----PRGQRGPTGPRGERGPRGITGKPGPKGNSGGDGPAGPPGERG 949

Query: 206 PPGRGTPMGMPPPGMRPPPPGMRGL 230
           P G   P G P P   P PPG  GL
Sbjct: 950 PNGPQGPTGFPGPKGPPGPPGKDGL 974



 Score = 45.4 bits (106), Expect = 4e-05
 Identities = 55/188 (29%), Positives = 62/188 (32%), Gaps = 58/188 (30%)

Query: 99   GAAGGPGIGRAAGRGIPAGVPMPQAPAGLAGPVRGVGGPSQQ----------------VM 142
            G AG PG     G   P G P P+ P G  G     G P Q+                V+
Sbjct: 940  GPAGPPGERGPNGPQGPTGFPGPKGPPGPPGKDGLPGHPGQRGETGFQGKTGPPGPPGVV 999

Query: 143  TPQG-RGTVAAAAAAATASIAGAPTQYP-------------------PGRGGPPP----P 178
             PQG  G              G P +                     PG+ GPP     P
Sbjct: 1000 GPQGPTGETGPMGERGHPGPPGPPGEQGLPGLAGKEGTKGDPGPAGLPGKDGPPGLRGFP 1059

Query: 179  MGRGAP-------------PPGMMGP--PPGMRPPMGP--PMGIPPGRGTPMGMPPPGMR 221
              RG P             PPG  GP   PG R P G   P+GI PGR  P G P P   
Sbjct: 1060 GDRGLPGPVGALGLKGNEGPPGPPGPAGSPGERGPAGAAGPIGI-PGRPGPQGPPGPAGE 1118

Query: 222  PPPPGMRG 229
               PG +G
Sbjct: 1119 KGAPGEKG 1126



 Score = 44.3 bits (103), Expect = 9e-05
 Identities = 57/187 (30%), Positives = 65/187 (34%), Gaps = 81/187 (43%)

Query: 102 GGPGIGRAAGRGIPA---------GVPMPQAPAGLAGPVRGVGGPSQQVMTPQGRGTVAA 152
           GGP  G    +G PA         G P P+ PAGL GP  G  GP+ QV  P  RG    
Sbjct: 446 GGPR-GEKGQKGEPAIIEPGMLIEGPPGPEGPAGLPGP-PGTMGPTGQVGDPGERG---- 499

Query: 153 AAAAATASIAGAPTQYPPGRGGPPPPMGRGAPPPGMM--------GPPPGMRPPM----- 199
                           PPGR G P   G   PP  M+        G   G + PM     
Sbjct: 500 ----------------PPGRPGLPGADGLPGPPGTMLMLPFRFGGGGDAGSKGPMVSAQE 543

Query: 200 ---------------GP--PMGI--------PPGRGTPMGMP-------PPGMRPPP--- 224
                          GP  PMG+        PPG G   G P       P G++ PP   
Sbjct: 544 SQAQAILQQARLALRGPAGPMGLTGRPGPVGPPGSGGLKGEPGDVGPQGPRGVQGPPGPA 603

Query: 225 --PGMRG 229
             PG RG
Sbjct: 604 GKPGRRG 610



 Score = 41.6 bits (96), Expect = 6e-04
 Identities = 54/169 (31%), Positives = 66/169 (39%), Gaps = 31/169 (18%)

Query: 80  MTVEGPPPKDTGIARVPLAGAAGGPG--IGRAAGRGIPAGVPMPQAPAGLAGPVRGVGGP 137
           M +EGPP  + G A +P      GP   +G    RG P    +P A  GL GP      P
Sbjct: 465 MLIEGPPGPE-GPAGLPGPPGTMGPTGQVGDPGERGPPGRPGLPGAD-GLPGP------P 516

Query: 138 SQQVMTP---QGRGTVAAAAAAATASIAGAPTQYPPGR---GGPPPPMGRGAPPPGMMGP 191
              +M P    G G   +     +A  + A       R    GP  PMG     PG +GP
Sbjct: 517 GTMLMLPFRFGGGGDAGSKGPMVSAQESQAQAILQQARLALRGPAGPMGL-TGRPGPVGP 575

Query: 192 P--------PGMRPPMGPPMGI--PPGRGTPMGMPPPGMRPPPPGMRGL 230
           P        PG   P G P G+  PPG   P G P    R    G RG+
Sbjct: 576 PGSGGLKGEPGDVGPQG-PRGVQGPPG---PAGKPGRRGRAGSDGARGM 620



 Score = 37.4 bits (85), Expect = 0.011
 Identities = 32/98 (32%), Positives = 40/98 (40%), Gaps = 8/98 (8%)

Query: 97   LAGAAGGPGI-GRAAGRGIPAGVPMPQAPAGLAGPVRGVGGPSQQVMTPQGRGTVAAAAA 155
            L G  G PG  G    RG+P     PQ  +G  G  +G+ GPS  +  P   G       
Sbjct: 1487 LIGLIGPPGEQGEKGDRGLPG----PQGSSGPKGE-QGITGPSGPIGPPGPPGLPGPPGP 1541

Query: 156  AATASIAGAPTQYPPGRGGPPPPMGRGAPPPGMMGPPP 193
                  +G PT  P G  G P P G   PP  ++ P P
Sbjct: 1542 KGAKGSSG-PTG-PKGEAGHPGPPGPPGPPGEVIQPLP 1577



 Score = 33.9 bits (76), Expect = 0.12
 Identities = 29/71 (40%), Positives = 32/71 (45%), Gaps = 13/71 (18%)

Query: 171 GRGGPPPPMGRGAPP----PGMM-GPPPGMRPPMGPPMGIPPGRGTPMG-MPPPGMRPPP 224
           G GGP    G+   P    PGM+   PPG   P G P   PPG   P G +  PG R PP
Sbjct: 444 GIGGPRGEKGQKGEPAIIEPGMLIEGPPGPEGPAGLPG--PPGTMGPTGQVGDPGERGPP 501

Query: 225 -----PGMRGL 230
                PG  GL
Sbjct: 502 GRPGLPGADGL 512


>gi|4826998 splicing factor proline/glutamine rich (polypyrimidine
           tract binding protein associated) [Homo sapiens]
          Length = 707

 Score = 64.7 bits (156), Expect = 6e-11
 Identities = 51/154 (33%), Positives = 56/154 (36%), Gaps = 25/154 (16%)

Query: 85  PPPKDTGIARVPLAGAAGGPGIGRAAGRGIPAGVPMPQAPAGLAGPVRGVGGPSQQVMTP 144
           PPP+D+    V     A GPG     G   PA    P A    +G   G           
Sbjct: 101 PPPQDSSKPVV-----AQGPGPAPGVGSAPPASSSAPPATPPTSGAPPG----------- 144

Query: 145 QGRGTVAAAAAAATASIAGAPTQYPPGRGGP-PPPMGRGAPPPGMMGPPPGMRPPMGPPM 203
            G G       A T++  GAP   PP  G P  PP   G PPP    P PG  P  GP  
Sbjct: 145 SGPGPTPTPPPAVTSAPPGAPPPTPPSSGVPTTPPQAGGPPPPPAAVPGPGPGPKQGPGP 204

Query: 204 GIPPGRGTPMGMPP--------PGMRPPPPGMRG 229
           G P G   P G  P        PG  P PP   G
Sbjct: 205 GGPKGGKMPGGPKPGGGPGLSTPGGHPKPPHRGG 238



 Score = 44.7 bits (104), Expect = 7e-05
 Identities = 48/157 (30%), Positives = 54/157 (34%), Gaps = 27/157 (17%)

Query: 99  GAAGGPGIGRAAGRGIPAGVPMPQAPAGLAGPVRGVGGPSQQVMTPQGRGTVAAAAAAAT 158
           G  GG G G    R  P G+ + Q   G  GP  G  GP   +  P              
Sbjct: 20  GGGGGRG-GLHDFRSPPPGMGLNQN-RGPMGPGPGQSGPKPPIPPPPPHQQQQQPPPQQP 77

Query: 159 ASIAGAPTQYPPG------RGGPPPPMGRG--------APPPGMMGPPPGMR--PPMGPP 202
                 P Q PP       +  PPPP             P PG+   PP     PP  PP
Sbjct: 78  PPQQPPPHQPPPHPQPHQQQQPPPPPQDSSKPVVAQGPGPAPGVGSAPPASSSAPPATPP 137

Query: 203 M-GIPPGRG---TPMGMP-----PPGMRPPPPGMRGL 230
             G PPG G   TP   P     PPG  PP P   G+
Sbjct: 138 TSGAPPGSGPGPTPTPPPAVTSAPPGAPPPTPPSSGV 174



 Score = 39.3 bits (90), Expect = 0.003
 Identities = 40/120 (33%), Positives = 43/120 (35%), Gaps = 32/120 (26%)

Query: 79  SMTVEGPPPKDTGIARVPLAGAAGGPGIGRAAGRGIPAGVPMPQAPAGLAGPVRGVGGPS 138
           S  V   PP+  G    P A    GPG  +  G G P G  MP       GP  G GGP 
Sbjct: 171 SSGVPTTPPQAGGPPPPPAAVPGPGPGPKQGPGPGGPKGGKMP------GGPKPG-GGPG 223

Query: 139 QQVMTPQGRGTVAAAAAAATASIAGAPTQYPPGRGGPPPPMGRGAPPP----GMMGPPPG 194
             + TP G                      PP RGG  P  GR   PP       GPPPG
Sbjct: 224 --LSTPGGH-------------------PKPPHRGGGEPRGGRQHHPPYHQQHHQGPPPG 262


>gi|160707881 formin 2 [Homo sapiens]
          Length = 1722

 Score = 64.3 bits (155), Expect = 8e-11
 Identities = 59/164 (35%), Positives = 68/164 (41%), Gaps = 31/164 (18%)

Query: 85   PPPKDTGIARVPLAGAAGGPGIGRAAGRGIPAGVPMPQAPAGLAGPVRGVGGPSQQVMTP 144
            PP    GI  +P    AG P      G  IP   P+P A   L  P+ G G P    +  
Sbjct: 924  PPLPGAGILPLPPLPGAGIPPPPPLPGAAIPPPPPLPGAGIPLPPPLPGAGIPPPPPLPG 983

Query: 145  QGRGTVAAAAAAATASIAGAPTQYP-PGRGGPPPPM--GRGAPPP------GMMGPPP-- 193
             G         A      G P   P PG G PPPP   G G PPP      G+  PPP  
Sbjct: 984  AGIPPPPPLPGA------GIPPPPPLPGAGIPPPPPLPGAGIPPPPPLPGAGIPPPPPLP 1037

Query: 194  --GMRPPMGPPM---GIPPGRGTP-MGMPPP------GMRPPPP 225
              G+ PP  PP+   GIPP    P  G+PPP      G+ PPPP
Sbjct: 1038 GAGIPPP--PPLPGAGIPPPPPLPGAGIPPPPPLPGAGIPPPPP 1079



 Score = 62.4 bits (150), Expect = 3e-10
 Identities = 58/166 (34%), Positives = 65/166 (39%), Gaps = 26/166 (15%)

Query: 85   PPPKDTGIARVPLAGAAGGPGIGRAAGRGIPAGVPMPQAPAGLAGPVRGVGGPSQQVMTP 144
            PP    GI   P    AG P      G GIP   P+P A      P+ G G P    +  
Sbjct: 1034 PPLPGAGIPPPPPLPGAGIPPPPPLPGAGIPPPPPLPGAGIPPPPPLPGAGIPPPPPLPG 1093

Query: 145  QGRGTVAAAAAAATASIAGAPTQYP-PGRGGPPPPM--GRGAPPP------GMMGPPPGM 195
             G                G P   P PG G PPPP   G G PPP      G+  PPP  
Sbjct: 1094 AGIPPPPPLPGV------GIPPPPPLPGAGIPPPPPLPGAGIPPPPPLPGAGIPPPPPLP 1147

Query: 196  R-----PPMGPPMGIP-----PGRGTPMGMPPPGMR-PPPPGMRGL 230
            R     PP  P  GIP     PG G P   P PG+  PPPP + G+
Sbjct: 1148 RVGIPPPPPLPGAGIPPPPPLPGAGIPPPPPLPGVGIPPPPPLPGV 1193



 Score = 61.2 bits (147), Expect = 7e-10
 Identities = 58/164 (35%), Positives = 66/164 (40%), Gaps = 42/164 (25%)

Query: 85   PPPKDTGIARVPLAGAAGGPGIGRAAGRGIPAGVPMPQAPAGLAGPVRGVGGPSQQVMTP 144
            PP    GI   P    AG P      G GIP   P+P A      P+ G G P    +  
Sbjct: 957  PPLPGAGIPLPPPLPGAGIPPPPPLPGAGIPPPPPLPGAGIPPPPPLPGAGIPPPPPLPG 1016

Query: 145  QGRGTVAAAAAAATASIAGAPTQYP-PGRGGPPPPM--GRGAPPP------GMMGPPP-- 193
                             AG P   P PG G PPPP   G G PPP      G+  PPP  
Sbjct: 1017 -----------------AGIPPPPPLPGAGIPPPPPLPGAGIPPPPPLPGAGIPPPPPLP 1059

Query: 194  --GMRPPMGPPM---GIPPGRGTP-MGMPPP------GMRPPPP 225
              G+ PP  PP+   GIPP    P  G+PPP      G+ PPPP
Sbjct: 1060 GAGIPPP--PPLPGAGIPPPPPLPGAGIPPPPPLPGAGIPPPPP 1101



 Score = 60.5 bits (145), Expect = 1e-09
 Identities = 59/164 (35%), Positives = 68/164 (41%), Gaps = 42/164 (25%)

Query: 85   PPPKDTGIARVPLAGAAGGPGIGRAAGRGIPAGVPMPQAPAGLAGPVRGVGGPSQQVMTP 144
            PP    GI   P    AG   +    G GIP   P+P A      P+ G G P    + P
Sbjct: 913  PPLPGAGIPPPPPLPGAGILPLPPLPGAGIPPPPPLPGAAIPPPPPLPGAGIP----LPP 968

Query: 145  QGRGTVAAAAAAATASIAGAPTQYP-PGRGGPPPPM--GRGAPPP------GMMGPPP-- 193
               G             AG P   P PG G PPPP   G G PPP      G+  PPP  
Sbjct: 969  PLPG-------------AGIPPPPPLPGAGIPPPPPLPGAGIPPPPPLPGAGIPPPPPLP 1015

Query: 194  --GMRPPMGPPM---GIPPGRGTP-MGMPPP------GMRPPPP 225
              G+ PP  PP+   GIPP    P  G+PPP      G+ PPPP
Sbjct: 1016 GAGIPPP--PPLPGAGIPPPPPLPGAGIPPPPPLPGAGIPPPPP 1057



 Score = 57.0 bits (136), Expect = 1e-08
 Identities = 60/172 (34%), Positives = 70/172 (40%), Gaps = 39/172 (22%)

Query: 77   LVSMTVEGPPPKDTGIARVPLAGAAGGPGIGRAAGRGIPAGVPMPQAPAGLAGPVRGVGG 136
            L S  +  PPP   G   +P       P      G GIP   P+P A      P+ G G 
Sbjct: 891  LPSTAIPQPPPLQ-GTEMLP-------PPPPPLPGAGIPPPPPLPGAGILPLPPLPGAGI 942

Query: 137  PSQQVMTPQGRGTVAAAAAAATASIAGAPTQYP-PGRGGPPPPM--GRGAPPP------G 187
            P    +        AA         AG P   P PG G PPPP   G G PPP      G
Sbjct: 943  PPPPPLPG------AAIPPPPPLPGAGIPLPPPLPGAGIPPPPPLPGAGIPPPPPLPGAG 996

Query: 188  MMGPPP----GMRPPMGPPM---GIPPGRGTP-MGMPPP------GMRPPPP 225
            +  PPP    G+ PP  PP+   GIPP    P  G+PPP      G+ PPPP
Sbjct: 997  IPPPPPLPGAGIPPP--PPLPGAGIPPPPPLPGAGIPPPPPLPGAGIPPPPP 1046



 Score = 54.7 bits (130), Expect = 7e-08
 Identities = 52/152 (34%), Positives = 59/152 (38%), Gaps = 16/152 (10%)

Query: 85   PPPKDTGIARVPLAGAAGGPGIGRAAGRGIPAGVPMPQAPAGLAGPVRGVGGPSQQVMTP 144
            PP    GI   P     G P      G GIP   P+P A      P+ GVG P    +  
Sbjct: 1133 PPLPGAGIPPPPPLPRVGIPPPPPLPGAGIPPPPPLPGAGIPPPPPLPGVGIPPPPPLPG 1192

Query: 145  QGRGTVAAAAAAATASIAGAPTQYP-PGRGGPPPPMGRGAPPPGMMGPPPGMRPPMGPPM 203
             G         A      G P   P PG G PP P     PPPG   PPP + P  GPP+
Sbjct: 1193 VGIPPPPPLPGA------GIPPPPPLPGMGIPPAP-APPLPPPGTGIPPPPLLPVSGPPL 1245

Query: 204  GIPPGRGTPMGMPPP---GMRPP--PPGMRGL 230
                G  T   +P P   G  PP  P G+ GL
Sbjct: 1246 LPQVGSST---LPTPQVCGFLPPPLPSGLFGL 1274



 Score = 48.5 bits (114), Expect = 5e-06
 Identities = 42/132 (31%), Positives = 54/132 (40%), Gaps = 19/132 (14%)

Query: 114 IPAGVPMPQAPAGLAGPVRGVGGPSQQVMTPQGRGTVAAAAAAATASIAGAPTQYPP--- 170
           IP+  P+P   +  + P  G+  P    +      T+ + A      + G     PP   
Sbjct: 855 IPSPPPLPCTESSSSMPGLGMVPPPPPPLPGMTVPTLPSTAIPQPPPLQGTEMLPPPPPP 914

Query: 171 --GRGGPPPPMGRGA------PPPGMMGPPPGMRP----PMGPPMGIPPGRGTPMGMPPP 218
             G G PPPP   GA      P PG   PPP   P    P  PP+   PG G P+  P P
Sbjct: 915 LPGAGIPPPPPLPGAGILPLPPLPGAGIPPPPPLPGAAIPPPPPL---PGAGIPLPPPLP 971

Query: 219 GMR-PPPPGMRG 229
           G   PPPP + G
Sbjct: 972 GAGIPPPPPLPG 983



 Score = 46.2 bits (108), Expect = 2e-05
 Identities = 53/172 (30%), Positives = 68/172 (39%), Gaps = 35/172 (20%)

Query: 79   SMTVEGPPPKDTGIARVPLAGAAGG-PGIGRAAGRGIPA-GVPMPQAPAGLAGPVRGVGG 136
            S  +  PPP       +P   ++   PG+G       P  G+ +P  P+        + G
Sbjct: 852  SCNIPSPPP-------LPCTESSSSMPGLGMVPPPPPPLPGMTVPTLPSTAIPQPPPLQG 904

Query: 137  PSQQVMTPQGRGTVAAAAAAATASIAGA---PTQYPPGRGGPPPPMGRGA---PPPGMMG 190
                 M P     +  A       + GA   P    PG G PPPP   GA   PPP + G
Sbjct: 905  TE---MLPPPPPPLPGAGIPPPPPLPGAGILPLPPLPGAGIPPPPPLPGAAIPPPPPLPG 961

Query: 191  -----PPP----GMRPPMG-PPMGIPPGRGTP-MGMPPP------GMRPPPP 225
                 PPP    G+ PP   P  GIPP    P  G+PPP      G+ PPPP
Sbjct: 962  AGIPLPPPLPGAGIPPPPPLPGAGIPPPPPLPGAGIPPPPPLPGAGIPPPPP 1013


>gi|110349772 alpha 1 type I collagen preproprotein [Homo sapiens]
          Length = 1464

 Score = 63.9 bits (154), Expect = 1e-10
 Identities = 58/160 (36%), Positives = 65/160 (40%), Gaps = 21/160 (13%)

Query: 83  EGPPPKDTGIARVPLA----GAAGGPGIGRAAGRGIPAGVPMPQAPAGLAGPVRGVGGPS 138
           E  PP   G A  P A    GA G PG   A G    AG P P  PAG  GP+  VG P 
Sbjct: 804 EPGPPGPAGFAGPPGADGQPGAKGEPGDAGAKG---DAGPPGPAGPAGPPGPIGNVGAPG 860

Query: 139 QQVMTPQGRGTVAAAAAAATASIAG-APTQYPPGRGGPPPPMG-----RGAPPPGMMGPP 192
            +      RG+     A      AG      P G  GPP P G      G  P G  GP 
Sbjct: 861 AK----GARGSAGPPGATGFPGAAGRVGPPGPSGNAGPPGPPGPAGKEGGKGPRGETGPA 916

Query: 193 --PGMRPPMGPPMGIPPGRGTPMGMPPPGMRPPPPGMRGL 230
             PG   P GPP G    +G+P G   P   P  PG +G+
Sbjct: 917 GRPGEVGPPGPP-GPAGEKGSP-GADGPAGAPGTPGPQGI 954



 Score = 62.8 bits (151), Expect = 2e-10
 Identities = 57/162 (35%), Positives = 61/162 (37%), Gaps = 24/162 (14%)

Query: 86  PPKDTGIARVP----LAGAAGGPGIGRAAGRGIPAGV---PMPQAPAGLAGPVRGVGGPS 138
           PP  TG A  P      GA G  G     G   P GV   P P  PAG AGP    G   
Sbjct: 333 PPGPTGPAGPPGFPGAVGAKGEAGPQGPRGSEGPQGVRGEPGPPGPAGAAGPAGNPGADG 392

Query: 139 QQVMTPQGRGTVAAAAAAATASIAGA-PTQYPPGRGGPPPPMGRGAPP--PGMMGP---- 191
           Q    P  +G   A   A      GA     P G GGPP P G    P  PG  G     
Sbjct: 393 Q----PGAKGANGAPGIAGAPGFPGARGPSGPQGPGGPPGPKGNSGEPGAPGSKGDTGAK 448

Query: 192 ----PPGMRPPMGPPMGIPPGRGTPMGMPPPGMRPPPPGMRG 229
               P G++ P GP      G+    G P P   P PPG RG
Sbjct: 449 GEPGPVGVQGPPGP--AGEEGKRGARGEPGPTGLPGPPGERG 488



 Score = 57.8 bits (138), Expect = 8e-09
 Identities = 58/181 (32%), Positives = 67/181 (37%), Gaps = 51/181 (28%)

Query: 98  AGAAGGPGIGRAAG-RGIP-----AGVPMPQAPAGLAGP-----------VRGVG---GP 137
           AGA G PG   A G +G+P     AG+P P+   G AGP           VRG+    GP
Sbjct: 712 AGAPGAPGSQGAPGLQGMPGERGAAGLPGPKGDRGDAGPKGADGSPGKDGVRGLTGPIGP 771

Query: 138 SQQVMTPQGRGTVAAAAAAATASIAGAPTQYPPGRGGPPPPMGRGAPP-----PGMMGP- 191
                 P  +G    +  A      GAP     G  GPP P G   PP     PG  G  
Sbjct: 772 PGPAGAPGDKGESGPSGPAGPTGARGAPGD--RGEPGPPGPAGFAGPPGADGQPGAKGEP 829

Query: 192 ----------PPGMRPPMGPP-----MGIPPGRGTPMGMPPPGM--------RPPPPGMR 228
                     PPG   P GPP     +G P  +G      PPG         R  PPG  
Sbjct: 830 GDAGAKGDAGPPGPAGPAGPPGPIGNVGAPGAKGARGSAGPPGATGFPGAAGRVGPPGPS 889

Query: 229 G 229
           G
Sbjct: 890 G 890



 Score = 57.0 bits (136), Expect = 1e-08
 Identities = 57/173 (32%), Positives = 69/173 (39%), Gaps = 39/173 (22%)

Query: 82  VEGPP--------------PKDTGIARVPLAGAAGGPGIGRAAGRGIPA--GVPMPQAPA 125
           V+GPP              P  TG+   P  G  GGPG      RG P   GV  P+ PA
Sbjct: 456 VQGPPGPAGEEGKRGARGEPGPTGLPGPP--GERGGPG-----SRGFPGADGVAGPKGPA 508

Query: 126 GLAGPVRGVGGPSQQVMTPQGRGTVAAAAAAATASIAGAP-TQYPPGRGGPPPPMGRGAP 184
           G     RG  GP+    +P   G    A       + G+P +  P G+ GPP P G+   
Sbjct: 509 G----ERGSPGPAGPKGSPGEAGRPGEAGLPGAKGLTGSPGSPGPDGKTGPPGPAGQDGR 564

Query: 185 PPGMMGPPPGMRPPMGPPMGIP--------PGRGTPMGMPPPGMRPPPPGMRG 229
           P G  G PPG R   G  MG P        PG+    G+P P     P G  G
Sbjct: 565 P-GPPG-PPGARGQAG-VMGFPGPKGAAGEPGKAGERGVPGPPGAVGPAGKDG 614



 Score = 55.1 bits (131), Expect = 5e-08
 Identities = 59/175 (33%), Positives = 65/175 (37%), Gaps = 45/175 (25%)

Query: 83  EGPPPKDTGIARVPLAGAAGGPGIGRAAG----------------RGIPA--GVPMPQAP 124
           +G P KD G+    L G  G PG   A G                RG P   G P P  P
Sbjct: 754 DGSPGKD-GVRG--LTGPIGPPGPAGAPGDKGESGPSGPAGPTGARGAPGDRGEPGPPGP 810

Query: 125 AGLAGPVRGVGGPSQQVMTPQGRGTVAAAAAAATASIAGAPTQYPPGRGGPPPPMGR-GA 183
           AG AGP    G P         +G    A A   A   G     P G  GPP P+G  GA
Sbjct: 811 AGFAGPPGADGQPG-------AKGEPGDAGAKGDAGPPG-----PAGPAGPPGPIGNVGA 858

Query: 184 P----PPGMMGPP-----PGMRPPMGPPMGIPPGRGTPMGMPPPGMRPPPPGMRG 229
           P      G  GPP     PG    +GPP   P G   P G P P  +    G RG
Sbjct: 859 PGAKGARGSAGPPGATGFPGAAGRVGPPG--PSGNAGPPGPPGPAGKEGGKGPRG 911



 Score = 53.5 bits (127), Expect = 1e-07
 Identities = 50/143 (34%), Positives = 56/143 (39%), Gaps = 17/143 (11%)

Query: 98   AGAAGGPGIGRAAGRGIPAGVPMPQAPAGLAGPVRGVGGPSQQVMT-PQGR-GTVAAAAA 155
            AG  G  G   AAGR  P G      P G  GP    GG   +  T P GR G V     
Sbjct: 868  AGPPGATGFPGAAGRVGPPGPSGNAGPPGPPGPAGKEGGKGPRGETGPAGRPGEVGPPGP 927

Query: 156  AATASIAGAP-TQYPPGRGGPPPPMGRGAPPPGMMGPP--------PGMRPPMGP----- 201
               A   G+P    P G  G P P G  A   G++G P        PG+  P G      
Sbjct: 928  PGPAGEKGSPGADGPAGAPGTPGPQGI-AGQRGVVGLPGQRGERGFPGLPGPSGEPGKQG 986

Query: 202  PMGIPPGRGTPMGMPPPGMRPPP 224
            P G    RG P  M PPG+  PP
Sbjct: 987  PSGASGERGPPGPMGPPGLAGPP 1009



 Score = 52.4 bits (124), Expect = 3e-07
 Identities = 46/143 (32%), Positives = 51/143 (35%), Gaps = 16/143 (11%)

Query: 99  GAAGGPGIGRAAGRGIPAGVPMPQAPAGLAGPVRGVGGPSQQVMTPQGRGTVAAAAAAAT 158
           GA G PGI  A G     G   PQ P G  GP    G P      P  +G   A      
Sbjct: 398 GANGAPGIAGAPGFPGARGPSGPQGPGGPPGPKGNSGEPG----APGSKGDTGAKGEPGP 453

Query: 159 ASIAGAP----TQYPPGRGGPPPPMGRGAPP-----PGMMGPP--PGMRPPMGPP-MGIP 206
             + G P     +   G  G P P G   PP     PG  G P   G+  P GP      
Sbjct: 454 VGVQGPPGPAGEEGKRGARGEPGPTGLPGPPGERGGPGSRGFPGADGVAGPKGPAGERGS 513

Query: 207 PGRGTPMGMPPPGMRPPPPGMRG 229
           PG   P G P    RP   G+ G
Sbjct: 514 PGPAGPKGSPGEAGRPGEAGLPG 536



 Score = 52.0 bits (123), Expect = 4e-07
 Identities = 75/211 (35%), Positives = 84/211 (39%), Gaps = 44/211 (20%)

Query: 41  ILCD---CDEFRKIKPKNSKQAEREEKRVLGLVLLRGENLVSMTVEGP--PPKDTGIARV 95
           +LCD   CDE      KN   AE  E     +     E+       G   P  DTG  R 
Sbjct: 68  VLCDDVICDE-----TKNCPGAEVPEGECCPVCPDGSESPTDQETTGVEGPKGDTG-PRG 121

Query: 96  PLAGAAGGPGIGRAAGRGIPAGVPMPQAPAGLAGPVRGVGGPSQQVMTPQGRGTVAAAAA 155
           P  G AG PG     G+    G+P P  P G  GP  G+GG       PQ          
Sbjct: 122 P-RGPAGPPGRDGIPGQ---PGLPGPPGPPGPPGPP-GLGGN----FAPQ---LSYGYDE 169

Query: 156 AATASIAGAPTQYPPG-RGGPPPPMGRGAP-PPGMMGPP-----PGMRPPMGP--PMGIP 206
            +T  I+      P G RG P PP   GAP P G  GPP     PG   PMGP  P G P
Sbjct: 170 KSTGGISVPGPMGPSGPRGLPGPP---GAPGPQGFQGPPGEPGEPGASGPMGPRGPPG-P 225

Query: 207 PGR-------GTPMGMPPPGMRPPPPGMRGL 230
           PG+       G P G P     P P G RGL
Sbjct: 226 PGKNGDDGEAGKP-GRPGERGPPGPQGARGL 255



 Score = 50.1 bits (118), Expect = 2e-06
 Identities = 59/177 (33%), Positives = 66/177 (37%), Gaps = 33/177 (18%)

Query: 74  GENLVSMTVEGPPPKDTGIARVPLAGAAGGPGIGRAAGRGIPAGVPMPQAPAGLAGPVRG 133
           G N       G   K TG   VP      GP +G +  RG+P G P    P G  GP   
Sbjct: 156 GGNFAPQLSYGYDEKSTGGISVP------GP-MGPSGPRGLP-GPPGAPGPQGFQGPPGE 207

Query: 134 VGGPSQQVMTPQG-RGTVAAAAAAATASIAGAPTQYPPGRGGPPPPMG-RGAPP----PG 187
            G P      P G RG             AG P +  PG  GPP P G RG P     PG
Sbjct: 208 PGEPGAS--GPMGPRGPPGPPGKNGDDGEAGKPGR--PGERGPPGPQGARGLPGTAGLPG 263

Query: 188 MMGPP-----PGMRPPMGP--PMGIP--------PGRGTPMGMPPPGMRPPPPGMRG 229
           M G        G +   GP  P G P        PG+  P G+P    RP  PG  G
Sbjct: 264 MKGHRGFSGLDGAKGDAGPAGPKGEPGSPGENGAPGQMGPRGLPGERGRPGAPGPAG 320



 Score = 49.3 bits (116), Expect = 3e-06
 Identities = 48/149 (32%), Positives = 54/149 (36%), Gaps = 19/149 (12%)

Query: 99  GAAGGPGIGRAAGRGIPAGVPMPQAPAGLAGP-----------VRGVGGPSQQVMTPQGR 147
           G  G PG   A G+  P G+P  +   G  GP             G  GP+     P   
Sbjct: 287 GEPGSPGENGAPGQMGPRGLPGERGRPGAPGPAGARGNDGATGAAGPPGPTGPAGPPGFP 346

Query: 148 GTVAAAAAAATASIAGAP-TQYPPGRGGPPPPMGRGAPP--PGMMGPPPGMRPPMGPP-- 202
           G V A   A      G+   Q   G  GPP P G   P   PG  G  PG +   G P  
Sbjct: 347 GAVGAKGEAGPQGPRGSEGPQGVRGEPGPPGPAGAAGPAGNPGADG-QPGAKGANGAPGI 405

Query: 203 MGIP--PGRGTPMGMPPPGMRPPPPGMRG 229
            G P  PG   P G   PG  P P G  G
Sbjct: 406 AGAPGFPGARGPSGPQGPGGPPGPKGNSG 434



 Score = 48.9 bits (115), Expect = 4e-06
 Identities = 54/156 (34%), Positives = 61/156 (39%), Gaps = 25/156 (16%)

Query: 86   PPKDTGIARVPLAGAAGGPGI-GRAAGRGIP-----AGVPMPQAPAGLAGPVRGVGGPSQ 139
            P  +TG A  P  G  G PG  G A  +G P     AG P    P G+AG    VG P Q
Sbjct: 909  PRGETGPAGRP--GEVGPPGPPGPAGEKGSPGADGPAGAPGTPGPQGIAGQRGVVGLPGQ 966

Query: 140  Q-----VMTPQGRGTVAAAAAAATASIAGAP-TQYPPGRGGPPPPMGR-GAP----PPGM 188
            +        P   G       +  +   G P    PPG  GPP   GR GAP     PG 
Sbjct: 967  RGERGFPGLPGPSGEPGKQGPSGASGERGPPGPMGPPGLAGPPGESGREGAPGAEGSPGR 1026

Query: 189  MGPP-----PGMRPPMGPPMGIPPGRGTPMGMPPPG 219
             G P      G   P GPP G P   G P  + P G
Sbjct: 1027 DGSPGAKGDRGETGPAGPP-GAPGAPGAPGPVGPAG 1061



 Score = 47.8 bits (112), Expect = 8e-06
 Identities = 57/162 (35%), Positives = 62/162 (38%), Gaps = 24/162 (14%)

Query: 84  GPPPKDTGIARVPLAGAAGGPGIGRAAG-RGIPAGVPMPQAPAGLAGPVRGVGGPSQQVM 142
           GPP +        + G  G PG   A G RG P G    Q P G AGP RG  G      
Sbjct: 650 GPPGEAGKPGEQGVPGDLGAPGPSGARGERGFP-GERGVQGPPGPAGP-RGANG------ 701

Query: 143 TPQGRGTVAAAAAAATASIAGAP-TQYPPGRGG----PPPPMGRG-APPPGMMGPP---- 192
            P   G    A A       GAP  Q  PG  G    P P   RG A P G  G P    
Sbjct: 702 APGNDGAKGDAGAPGAPGSQGAPGLQGMPGERGAAGLPGPKGDRGDAGPKGADGSPGKDG 761

Query: 193 -PGMRPPMGP--PMGIPPGRGT--PMGMPPPGMRPPPPGMRG 229
             G+  P+GP  P G P  +G   P G   P      PG RG
Sbjct: 762 VRGLTGPIGPPGPAGAPGDKGESGPSGPAGPTGARGAPGDRG 803



 Score = 47.8 bits (112), Expect = 8e-06
 Identities = 60/182 (32%), Positives = 66/182 (36%), Gaps = 44/182 (24%)

Query: 83   EGPPPKDTGIARVPLAGAAGGPGIGRAAGRGIPAGVPMPQAP---------------AGL 127
            EG P  +    R    GA G  G    AG     G P    P               AG 
Sbjct: 1015 EGAPGAEGSPGRDGSPGAKGDRGETGPAGPPGAPGAPGAPGPVGPAGKSGDRGETGPAGP 1074

Query: 128  AGPVRGVG--GPSQQVMTPQG-RGTVAAAAAAATASIAG----APTQYPPGRGGPP---P 177
            AGPV  VG  GP+     PQG RG            I G    +  Q PPG  G P    
Sbjct: 1075 AGPVGPVGARGPA----GPQGPRGDKGETGEQGDRGIKGHRGFSGLQGPPGPPGSPGEQG 1130

Query: 178  PMGRGAP-----PPGMMGPP-----PGMRPPMGPPMGIPPGR---GTPMGMPPPGMRPPP 224
            P G   P     PPG  G P      G+  P+GPP   P GR     P+G P P   P P
Sbjct: 1131 PSGASGPAGPRGPPGSAGAPGKDGLNGLPGPIGPPG--PRGRTGDAGPVGPPGPPGPPGP 1188

Query: 225  PG 226
            PG
Sbjct: 1189 PG 1190



 Score = 47.8 bits (112), Expect = 8e-06
 Identities = 57/176 (32%), Positives = 63/176 (35%), Gaps = 47/176 (26%)

Query: 89   DTGIARVPLA-GAAGGPGIGRAAGRGIPAGVPMPQAPAGLAGPVRGVGGPSQQVMTPQG- 146
            +TG A  P A GA G PG    AG+    G   P  PAG  GPV G  GP+     PQG 
Sbjct: 1038 ETGPAGPPGAPGAPGAPGPVGPAGKSGDRGETGPAGPAGPVGPV-GARGPAG----PQGP 1092

Query: 147  RGTVAAAAAAATASIAG----------------------------APTQYPPGRGGPPPP 178
            RG            I G                            A  + PPG  G P  
Sbjct: 1093 RGDKGETGEQGDRGIKGHRGFSGLQGPPGPPGSPGEQGPSGASGPAGPRGPPGSAGAPGK 1152

Query: 179  MGRGAPPPGMMGPP-----PGMRPPMGPPMGIPPGRGTPMGMPPPG----MRPPPP 225
             G     PG +GPP      G   P+GPP   PPG   P G P  G      P PP
Sbjct: 1153 DGLNG-LPGPIGPPGPRGRTGDAGPVGPPG--PPGPPGPPGPPSAGFDFSFLPQPP 1205



 Score = 47.4 bits (111), Expect = 1e-05
 Identities = 50/157 (31%), Positives = 55/157 (35%), Gaps = 28/157 (17%)

Query: 97   LAGAAGGPGIGRAAGRGIPAGVPMPQAPAGLAGP--VRGVGGPSQQVMTPQGRGTVAAAA 154
            L G +G PG    +G     G P P  P GLAGP    G  G      +P   G+  A  
Sbjct: 975  LPGPSGEPGKQGPSGASGERGPPGPMGPPGLAGPPGESGREGAPGAEGSPGRDGSPGAKG 1034

Query: 155  AAATASIAGAP-TQYPPGRGGPPPPMGRGAP-----PPGMMGP--PPGMRPPMGP----- 201
                   AG P     PG  GP  P G+        P G  GP  P G R P GP     
Sbjct: 1035 DRGETGPAGPPGAPGAPGAPGPVGPAGKSGDRGETGPAGPAGPVGPVGARGPAGPQGPRG 1094

Query: 202  ---------PMGIPPGRGTPMGMPPPGMRPPPPGMRG 229
                       GI   RG      PPG    PPG  G
Sbjct: 1095 DKGETGEQGDRGIKGHRGFSGLQGPPG----PPGSPG 1127



 Score = 46.6 bits (109), Expect = 2e-05
 Identities = 53/155 (34%), Positives = 59/155 (38%), Gaps = 31/155 (20%)

Query: 99  GAAGGPGIGRAAGRGIPAGVPMPQAPAGLAGPVRGVGGPSQQVMTPQGRGTVAAAAAAAT 158
           G  G PG    AG+   AG   P  PAG AG  RG  GP+    +P  +G    A     
Sbjct: 599 GVPGPPGAVGPAGKDGEAGAQGPPGPAGPAGE-RGEQGPAG---SPGFQGLPGPAGPPGE 654

Query: 159 ASIAGAPTQYPPGRGGPPPPMG----RGAP-------PPGMMGP--------PPGMRPPM 199
           A   G   Q  PG  G P P G    RG P       PPG  GP          G +   
Sbjct: 655 AGKPG--EQGVPGDLGAPGPSGARGERGFPGERGVQGPPGPAGPRGANGAPGNDGAKGDA 712

Query: 200 GPPMGIPPGRGTPMGMPPPGMR-----PPPPGMRG 229
           G P G P  +G P     PG R     P P G RG
Sbjct: 713 GAP-GAPGSQGAPGLQGMPGERGAAGLPGPKGDRG 746



 Score = 44.7 bits (104), Expect = 7e-05
 Identities = 47/134 (35%), Positives = 53/134 (39%), Gaps = 25/134 (18%)

Query: 99  GAAGGPGIGRAAGRGIPAGVPMPQAPAGLAGPVRGVGGPSQQVMTPQGRGTVAAAAAAAT 158
           GAAG PG  +A  RG+P G P    PAG  G     G P          G    A     
Sbjct: 587 GAAGEPG--KAGERGVP-GPPGAVGPAGKDGEAGAQGPP----------GPAGPAGERGE 633

Query: 159 ASIAGAP-TQYPPGRGGPPPPMGRGAPPPGMMGPPPGMRPPMGPPMGIPPGRGTP--MGM 215
              AG+P  Q  PG  GPP   G+    PG  G P  +  P   P G    RG P   G+
Sbjct: 634 QGPAGSPGFQGLPGPAGPPGEAGK----PGEQGVPGDLGAP--GPSGARGERGFPGERGV 687

Query: 216 PPPGMRPPPPGMRG 229
             P   P P G RG
Sbjct: 688 QGP---PGPAGPRG 698


>gi|4557317 annexin A11 [Homo sapiens]
          Length = 505

 Score = 63.9 bits (154), Expect = 1e-10
 Identities = 54/136 (39%), Positives = 57/136 (41%), Gaps = 31/136 (22%)

Query: 115 PAGVPMPQAPAGLAGPVRGVGGPSQQVMTPQGRGTVA--------------AAAAAATAS 160
           P G P P AP G  GP  G   P    M P G   VA              AA  + T  
Sbjct: 10  PGGYP-PAAPGG--GPWGGAAYPPPPSMPPIGLDNVATYAGQFNQDYLSGMAANMSGTFG 66

Query: 161 IAGAPTQYP--PGRGGPP-PPMGRGAPP-------PGMMGPPPGMRPPMGPPMGIPPGRG 210
            A  P  YP  PG G PP PP G G PP       P  M PPPG  PP   P   PP  G
Sbjct: 67  GANMPNLYPGAPGAGYPPVPPGGFGQPPSAQQPVPPYGMYPPPGGNPPSRMP-SYPPYPG 125

Query: 211 TPM---GMPPPGMRPP 223
            P+    MPPPG +PP
Sbjct: 126 APVPGQPMPPPGQQPP 141



 Score = 47.4 bits (111), Expect = 1e-05
 Identities = 45/141 (31%), Positives = 52/141 (36%), Gaps = 37/141 (26%)

Query: 97  LAGAAGGPGIGRAAGRGIPAGVPMPQAPAGLAGPVRGVGGPSQQVMTPQGRGTVAAAAAA 156
           ++G  GG  +         AG P P  P G   P       +QQ + P G          
Sbjct: 61  MSGTFGGANMPNLYPGAPGAGYP-PVPPGGFGQPPS-----AQQPVPPYG---------- 104

Query: 157 ATASIAGAPTQYPPGRGGPPP-----PMGRGAPPPGMMGPPPGMRPPMGPPMGIPPGRGT 211
                      YPP  G PP      P   GAP PG   PPPG +PP   P G PP   T
Sbjct: 105 ----------MYPPPGGNPPSRMPSYPPYPGAPVPGQPMPPPGQQPPGAYP-GQPP--VT 151

Query: 212 PMGMPP---PGMRPPPPGMRG 229
             G PP   PG + P P   G
Sbjct: 152 YPGQPPVPLPGQQQPVPSYPG 172



 Score = 36.2 bits (82), Expect = 0.024
 Identities = 31/106 (29%), Positives = 33/106 (31%), Gaps = 47/106 (44%)

Query: 168 YPPGRGGPPPPMGRGAPPPGMMGPPPGMRPPMG--------------------------- 200
           YPP  GG PP    G P  G   PPP   PP+G                           
Sbjct: 6   YPPPPGGYPPAAPGGGPWGGAAYPPPPSMPPIGLDNVATYAGQFNQDYLSGMAANMSGTF 65

Query: 201 ------------PPMGIPP----GRGTP----MGMPPPGMRPPPPG 226
                       P  G PP    G G P      +PP GM PPP G
Sbjct: 66  GGANMPNLYPGAPGAGYPPVPPGGFGQPPSAQQPVPPYGMYPPPGG 111



 Score = 28.5 bits (62), Expect = 5.1
 Identities = 17/37 (45%), Positives = 18/37 (48%), Gaps = 5/37 (13%)

Query: 191 PPPGMRPPMGPPMGIPPGRGTPMGMPPPGMRPPPPGM 227
           PPPG  PP  P  G   G   P   PPP M  PP G+
Sbjct: 8   PPPGGYPPAAPGGGPWGGAAYP---PPPSM--PPIGL 39


>gi|22165433 annexin A11 [Homo sapiens]
          Length = 505

 Score = 63.9 bits (154), Expect = 1e-10
 Identities = 54/136 (39%), Positives = 57/136 (41%), Gaps = 31/136 (22%)

Query: 115 PAGVPMPQAPAGLAGPVRGVGGPSQQVMTPQGRGTVA--------------AAAAAATAS 160
           P G P P AP G  GP  G   P    M P G   VA              AA  + T  
Sbjct: 10  PGGYP-PAAPGG--GPWGGAAYPPPPSMPPIGLDNVATYAGQFNQDYLSGMAANMSGTFG 66

Query: 161 IAGAPTQYP--PGRGGPP-PPMGRGAPP-------PGMMGPPPGMRPPMGPPMGIPPGRG 210
            A  P  YP  PG G PP PP G G PP       P  M PPPG  PP   P   PP  G
Sbjct: 67  GANMPNLYPGAPGAGYPPVPPGGFGQPPSAQQPVPPYGMYPPPGGNPPSRMP-SYPPYPG 125

Query: 211 TPM---GMPPPGMRPP 223
            P+    MPPPG +PP
Sbjct: 126 APVPGQPMPPPGQQPP 141



 Score = 47.4 bits (111), Expect = 1e-05
 Identities = 45/141 (31%), Positives = 52/141 (36%), Gaps = 37/141 (26%)

Query: 97  LAGAAGGPGIGRAAGRGIPAGVPMPQAPAGLAGPVRGVGGPSQQVMTPQGRGTVAAAAAA 156
           ++G  GG  +         AG P P  P G   P       +QQ + P G          
Sbjct: 61  MSGTFGGANMPNLYPGAPGAGYP-PVPPGGFGQPPS-----AQQPVPPYG---------- 104

Query: 157 ATASIAGAPTQYPPGRGGPPP-----PMGRGAPPPGMMGPPPGMRPPMGPPMGIPPGRGT 211
                      YPP  G PP      P   GAP PG   PPPG +PP   P G PP   T
Sbjct: 105 ----------MYPPPGGNPPSRMPSYPPYPGAPVPGQPMPPPGQQPPGAYP-GQPP--VT 151

Query: 212 PMGMPP---PGMRPPPPGMRG 229
             G PP   PG + P P   G
Sbjct: 152 YPGQPPVPLPGQQQPVPSYPG 172



 Score = 36.2 bits (82), Expect = 0.024
 Identities = 31/106 (29%), Positives = 33/106 (31%), Gaps = 47/106 (44%)

Query: 168 YPPGRGGPPPPMGRGAPPPGMMGPPPGMRPPMG--------------------------- 200
           YPP  GG PP    G P  G   PPP   PP+G                           
Sbjct: 6   YPPPPGGYPPAAPGGGPWGGAAYPPPPSMPPIGLDNVATYAGQFNQDYLSGMAANMSGTF 65

Query: 201 ------------PPMGIPP----GRGTP----MGMPPPGMRPPPPG 226
                       P  G PP    G G P      +PP GM PPP G
Sbjct: 66  GGANMPNLYPGAPGAGYPPVPPGGFGQPPSAQQPVPPYGMYPPPGG 111



 Score = 28.5 bits (62), Expect = 5.1
 Identities = 17/37 (45%), Positives = 18/37 (48%), Gaps = 5/37 (13%)

Query: 191 PPPGMRPPMGPPMGIPPGRGTPMGMPPPGMRPPPPGM 227
           PPPG  PP  P  G   G   P   PPP M  PP G+
Sbjct: 8   PPPGGYPPAAPGGGPWGGAAYP---PPPSM--PPIGL 39


>gi|22165431 annexin A11 [Homo sapiens]
          Length = 505

 Score = 63.9 bits (154), Expect = 1e-10
 Identities = 54/136 (39%), Positives = 57/136 (41%), Gaps = 31/136 (22%)

Query: 115 PAGVPMPQAPAGLAGPVRGVGGPSQQVMTPQGRGTVA--------------AAAAAATAS 160
           P G P P AP G  GP  G   P    M P G   VA              AA  + T  
Sbjct: 10  PGGYP-PAAPGG--GPWGGAAYPPPPSMPPIGLDNVATYAGQFNQDYLSGMAANMSGTFG 66

Query: 161 IAGAPTQYP--PGRGGPP-PPMGRGAPP-------PGMMGPPPGMRPPMGPPMGIPPGRG 210
            A  P  YP  PG G PP PP G G PP       P  M PPPG  PP   P   PP  G
Sbjct: 67  GANMPNLYPGAPGAGYPPVPPGGFGQPPSAQQPVPPYGMYPPPGGNPPSRMP-SYPPYPG 125

Query: 211 TPM---GMPPPGMRPP 223
            P+    MPPPG +PP
Sbjct: 126 APVPGQPMPPPGQQPP 141



 Score = 47.4 bits (111), Expect = 1e-05
 Identities = 45/141 (31%), Positives = 52/141 (36%), Gaps = 37/141 (26%)

Query: 97  LAGAAGGPGIGRAAGRGIPAGVPMPQAPAGLAGPVRGVGGPSQQVMTPQGRGTVAAAAAA 156
           ++G  GG  +         AG P P  P G   P       +QQ + P G          
Sbjct: 61  MSGTFGGANMPNLYPGAPGAGYP-PVPPGGFGQPPS-----AQQPVPPYG---------- 104

Query: 157 ATASIAGAPTQYPPGRGGPPP-----PMGRGAPPPGMMGPPPGMRPPMGPPMGIPPGRGT 211
                      YPP  G PP      P   GAP PG   PPPG +PP   P G PP   T
Sbjct: 105 ----------MYPPPGGNPPSRMPSYPPYPGAPVPGQPMPPPGQQPPGAYP-GQPP--VT 151

Query: 212 PMGMPP---PGMRPPPPGMRG 229
             G PP   PG + P P   G
Sbjct: 152 YPGQPPVPLPGQQQPVPSYPG 172



 Score = 36.2 bits (82), Expect = 0.024
 Identities = 31/106 (29%), Positives = 33/106 (31%), Gaps = 47/106 (44%)

Query: 168 YPPGRGGPPPPMGRGAPPPGMMGPPPGMRPPMG--------------------------- 200
           YPP  GG PP    G P  G   PPP   PP+G                           
Sbjct: 6   YPPPPGGYPPAAPGGGPWGGAAYPPPPSMPPIGLDNVATYAGQFNQDYLSGMAANMSGTF 65

Query: 201 ------------PPMGIPP----GRGTP----MGMPPPGMRPPPPG 226
                       P  G PP    G G P      +PP GM PPP G
Sbjct: 66  GGANMPNLYPGAPGAGYPPVPPGGFGQPPSAQQPVPPYGMYPPPGG 111



 Score = 28.5 bits (62), Expect = 5.1
 Identities = 17/37 (45%), Positives = 18/37 (48%), Gaps = 5/37 (13%)

Query: 191 PPPGMRPPMGPPMGIPPGRGTPMGMPPPGMRPPPPGM 227
           PPPG  PP  P  G   G   P   PPP M  PP G+
Sbjct: 8   PPPGGYPPAAPGGGPWGGAAYP---PPPSM--PPIGL 39


>gi|7706501 WW domain binding protein 11 [Homo sapiens]
          Length = 641

 Score = 63.2 bits (152), Expect = 2e-10
 Identities = 55/156 (35%), Positives = 67/156 (42%), Gaps = 36/156 (23%)

Query: 84  GPPPKDTGIARVPLAGAAGGPGIGRAAGRGIPAGVPMPQAPAGLAGP-VRGVGGPSQQVM 142
           GPPP   G    P     G P        G+P G P P AP  L  P + G+ GP  +++
Sbjct: 409 GPPP--LGPPPAPPLRPPGPP-------TGLPPGPP-PGAPPFLRPPGMPGLRGPLPRLL 458

Query: 143 TPQGRGTVAAAAAAATASIAGAPTQYPPGR--GGPPPPMGRGAPP-------PGMMGPPP 193
            P                  G P   PPG   G PP P  RG PP       PG+  P P
Sbjct: 459 PP--------------GPPPGRPPGPPPGPPPGLPPGPPPRGPPPRLPPPAPPGIPPPRP 504

Query: 194 GM-RPPMGPPMG-IPPGRGTPMGMPPPGMRPPPPGM 227
           GM RPP+ PP+G  PPG   P  +P PG+   PP +
Sbjct: 505 GMMRPPLVPPLGPAPPGLFPPAPLPNPGVLSAPPNL 540



 Score = 55.5 bits (132), Expect = 4e-08
 Identities = 40/103 (38%), Positives = 48/103 (46%), Gaps = 24/103 (23%)

Query: 146 GRGTVAAAAAAATASIAGAPTQYPPGRGGPP------PPMGRGAPPPGMM-GPPPG---- 194
           G  T ++   A   S+  +  Q PP  G PP      PP+    PP G+  GPPPG    
Sbjct: 382 GTSTASSQQQAPPQSVPPSQIQAPPMPGPPPLGPPPAPPLRPPGPPTGLPPGPPPGAPPF 441

Query: 195 MRPPMGP----------PMGIPPGR--GTPMGMPPPGMRPPPP 225
           +RPP  P          P G PPGR  G P G PPPG+ P PP
Sbjct: 442 LRPPGMPGLRGPLPRLLPPGPPPGRPPGPPPG-PPPGLPPGPP 483



 Score = 45.1 bits (105), Expect = 5e-05
 Identities = 32/81 (39%), Positives = 39/81 (48%), Gaps = 19/81 (23%)

Query: 155 AAATASIAGAPTQYPPGRGGPPPPMGRGAPPPGMMGPPPGMRPPMGPPMGIPPGRGTPMG 214
           + A++     P   PP +   PP  G   PPP  +GPPP   PP+ PP       G P G
Sbjct: 384 STASSQQQAPPQSVPPSQIQAPPMPG---PPP--LGPPPA--PPLRPP-------GPPTG 429

Query: 215 M---PPPGMRP--PPPGMRGL 230
           +   PPPG  P   PPGM GL
Sbjct: 430 LPPGPPPGAPPFLRPPGMPGL 450



 Score = 28.5 bits (62), Expect = 5.1
 Identities = 29/93 (31%), Positives = 39/93 (41%), Gaps = 10/93 (10%)

Query: 120 MPQAPAGLAG---PVRGVGGPSQQVMTPQGRGTVAAAAAAATASIAGAPTQYPPGRGGPP 176
           MP AP+ +     P+ G   PS    T    G    A +       G P + PPGR  P 
Sbjct: 144 MPHAPSNILIQDIPLPGAQPPSILKKT-SAYGPPTRAVSILPLLGHGVP-RLPPGRKPPG 201

Query: 177 PPMGRGAPPPGMMGPPPGMRPPMGPPMGIPPGR 209
           PP G   PPP  +    G +  +G  + +PP R
Sbjct: 202 PPPG---PPPPQVVQMYGRK--VGFALDLPPRR 229


>gi|209571537 proline-rich protein BstNI subfamily 2 [Homo sapiens]
          Length = 416

 Score = 62.8 bits (151), Expect = 2e-10
 Identities = 51/157 (32%), Positives = 62/157 (39%), Gaps = 14/157 (8%)

Query: 83  EGPPPKDTG---IARVPLAGAAGGPGIGRAAGRGIPAGVPMPQAPAGLAG-PVRGVGGPS 138
           +GPPP+       AR P     G P  G    +G P     PQ P    G   +G   P 
Sbjct: 222 QGPPPQGDNKSQSARSPPGKPQGPPPQGGNQPQGPPPPPGKPQGPPPQGGNKPQGPPPPG 281

Query: 139 QQVMTPQGRGTVAAAAAAATASIAGAPTQYPPGRG----GPPPPMGRGAPPPGMMGPPPG 194
           +    PQG      + + ++ S  G P   PP  G    GPPPP G+   PP   G  P 
Sbjct: 282 K----PQGPPPQGGSKSRSSRSPPGKPQGPPPQGGNQPQGPPPPPGKPQGPPPQGGNKPQ 337

Query: 195 MRPPMGPPMGIPP--GRGTPMGMPPPGMRPPPPGMRG 229
             PP G P G PP  G  +     PPG    PP   G
Sbjct: 338 GPPPPGKPQGPPPQGGSKSRSARSPPGKPQGPPQQEG 374



 Score = 58.5 bits (140), Expect = 5e-09
 Identities = 54/172 (31%), Positives = 61/172 (35%), Gaps = 29/172 (16%)

Query: 83  EGPPPKDTGIARVPLAGAAGGPGIGRAAGRGIPAGVPMPQAPAG-----------LAGPV 131
           +GPPP+     + P     G P      G   P G P P  P G            + P 
Sbjct: 58  QGPPPQGGNQPQGP-PPPPGKPQGPPPQGGNKPQGPPPPGKPQGPPPQGDKSRSPRSPPG 116

Query: 132 RGVGGPSQQVMTPQGRGTVAAAAAAATASIAGAPT-QYPPGRGGPPPPMGRG------AP 184
           +  G P Q    PQG                  P    PPG+   PPP G        +P
Sbjct: 117 KPQGPPPQGGNQPQGPPPPPGKPQGPPPQGGNKPQGPPPPGKPQGPPPQGDNKSRSSRSP 176

Query: 185 PPGMMGPPP-------GMRPPMGPPMGIPP-GRGTPMGMPPPG--MRPPPPG 226
           P    GPPP       G  PP G P G PP G   P G PPPG    PPP G
Sbjct: 177 PGKPQGPPPQGGNQPQGPPPPPGKPQGPPPQGGNKPQGPPPPGKPQGPPPQG 228



 Score = 58.5 bits (140), Expect = 5e-09
 Identities = 58/174 (33%), Positives = 69/174 (39%), Gaps = 35/174 (20%)

Query: 83  EGPPPKD--TGIARVPLAGAAGGPGIGRAAGRGIPAGVPMPQAPAGLAG-PVRGVGGPSQ 139
           +GPPP+   +   R P     G P  G    +G P     PQ P    G   +G   P +
Sbjct: 99  QGPPPQGDKSRSPRSPPGKPQGPPPQGGNQPQGPPPPPGKPQGPPPQGGNKPQGPPPPGK 158

Query: 140 QVMTPQGRGTVAAAAAAATASIAGAPTQYPPGRG----GPPPPMG-------------RG 182
               PQG        + ++ S  G P   PP  G    GPPPP G             +G
Sbjct: 159 ----PQGPPPQGDNKSRSSRSPPGKPQGPPPQGGNQPQGPPPPPGKPQGPPPQGGNKPQG 214

Query: 183 APPPGM-MGPPP-------GMRPPMGPPMGIPP-GRGTPMGMPPPGMRP--PPP 225
            PPPG   GPPP         R P G P G PP G   P G PPP  +P  PPP
Sbjct: 215 PPPPGKPQGPPPQGDNKSQSARSPPGKPQGPPPQGGNQPQGPPPPPGKPQGPPP 268



 Score = 57.8 bits (138), Expect = 8e-09
 Identities = 45/133 (33%), Positives = 57/133 (42%), Gaps = 18/133 (13%)

Query: 109 AAGRGIPAGVPMPQAPAGLAGPVRGVGGPSQQVMTPQGRGTVAAAAAAATASIAGAPTQY 168
           ++ + +   V   ++P+ +AG  +G   P Q    PQG  +               P   
Sbjct: 14  SSAQNLNEDVSQEESPSLIAGNPQGA--PPQGGNKPQGPPSPPGKPQGPPPQGGNQPQGP 71

Query: 169 PPGRGGP--PPPMG----RGAPPPGM-MGPPP------GMRPPMGPPMGIPP-GRGTPMG 214
           PP  G P  PPP G    +G PPPG   GPPP        R P G P G PP G   P G
Sbjct: 72  PPPPGKPQGPPPQGGNKPQGPPPPGKPQGPPPQGDKSRSPRSPPGKPQGPPPQGGNQPQG 131

Query: 215 MPPPGMRP--PPP 225
            PPP  +P  PPP
Sbjct: 132 PPPPPGKPQGPPP 144



 Score = 57.0 bits (136), Expect = 1e-08
 Identities = 48/170 (28%), Positives = 62/170 (36%), Gaps = 19/170 (11%)

Query: 76  NLVSMTVEGPPPKDTGIARVPLAGAA---GGPGIGRAAGRGIPAGVPMPQAPAGLAGPVR 132
           +L++   +G PP+     + P +      G P  G    +G P     PQ P    G   
Sbjct: 30  SLIAGNPQGAPPQGGNKPQGPPSPPGKPQGPPPQGGNQPQGPPPPPGKPQGPPPQGGNKP 89

Query: 133 GVGGPSQQVMTPQGRGTVAAAAAAATASIAGAPTQYPPGRGGPPPPMGRGAPPPGMMGPP 192
               P  +   P  +G  + +  +      G P Q      GPPPP G+   PP   G  
Sbjct: 90  QGPPPPGKPQGPPPQGDKSRSPRSPPGKPQGPPPQGGNQPQGPPPPPGKPQGPPPQGGNK 149

Query: 193 PGMRPPMGPPMGIPP-----------GRGTPMGMPPPGMR-----PPPPG 226
           P   PP G P G PP             G P G PP G       PPPPG
Sbjct: 150 PQGPPPPGKPQGPPPQGDNKSRSSRSPPGKPQGPPPQGGNQPQGPPPPPG 199



 Score = 46.2 bits (108), Expect = 2e-05
 Identities = 43/138 (31%), Positives = 54/138 (39%), Gaps = 10/138 (7%)

Query: 83  EGPPPKD---TGIARVPLAGAAGGPGIGRAAGRGIPAGVPMPQAPAGLAG-PVRGVGGPS 138
           +GPPP+    +  +R P     G P  G    +G P     PQ P    G   +G   P 
Sbjct: 284 QGPPPQGGSKSRSSRSPPGKPQGPPPQGGNQPQGPPPPPGKPQGPPPQGGNKPQGPPPPG 343

Query: 139 QQVMTPQGRGTVAAAAAAATASIAGAPTQYPPGRGGPPPPMGRGAPPPGMMGPPPGMRPP 198
           +    P   G+ + +A +      G P Q      GPPPP G G P      PP G   P
Sbjct: 344 KPQGPPPQGGSKSRSARSPPGKPQGPPQQEGNNPQGPPPPAG-GNPQQ-PQAPPAGQ--P 399

Query: 199 MGPPMGIPPGRGTPMGMP 216
            GPP   PP  G P   P
Sbjct: 400 QGPPR--PPQGGRPSRPP 415



 Score = 38.5 bits (88), Expect = 0.005
 Identities = 46/150 (30%), Positives = 53/150 (35%), Gaps = 17/150 (11%)

Query: 83  EGPPPKDTGIAR-VPLAGAAGGP---GIGRAAGRGIPAGVPMPQAPAGLAGPVRGVGGPS 138
           +GPPP+     +  P  G   GP   G  ++     P G P    P G   P     GP 
Sbjct: 264 QGPPPQGGNKPQGPPPPGKPQGPPPQGGSKSRSSRSPPGKPQGPPPQGGNQPQ----GPP 319

Query: 139 QQVMTPQGRGTVAAAAAAATASIAGAPTQYPPGRGGPPPPMGRGAPPPGMMGPPPGM-RP 197
                PQG                G P Q PP +GG      R +PP    GPP      
Sbjct: 320 PPPGKPQGPPPQGGNKPQGPPP-PGKP-QGPPPQGGSKSRSAR-SPPGKPQGPPQQEGNN 376

Query: 198 PMGPPMGIPPGRGTPM--GMPPPGMRPPPP 225
           P GPP   PP  G P     PP G    PP
Sbjct: 377 PQGPP---PPAGGNPQQPQAPPAGQPQGPP 403


>gi|157168329 formin 1 [Homo sapiens]
          Length = 1196

 Score = 62.0 bits (149), Expect = 4e-10
 Identities = 51/153 (33%), Positives = 62/153 (40%), Gaps = 33/153 (21%)

Query: 76  NLVSMTVEGPPP--KDTGIARVPLAGAAGGPGIGRAAGRGIPAGVPMPQAPAGLAGPVRG 133
           N+ S++   PP   KD   A  P+ G A      + A    PA +P P            
Sbjct: 611 NISSLSQLSPPNDHKDIHAALQPMEGMASNQ---QKALPPPPASIPPPPP---------- 657

Query: 134 VGGPSQQVMTPQGRGTVAAAAAAATASIAGAPTQYPPGRGGPPPPMGRGAPPPGMMGPPP 193
                     P G G+++ A      S AG P   PP    PPPP+    PPP   GPPP
Sbjct: 658 ---------LPSGLGSLSPAPPMPPVS-AGPPLPPPPP---PPPPL----PPPSSAGPPP 700

Query: 194 GMRPPMGPPMGIPPG-RGTPMGMPPPGMRPPPP 225
              PP  P    PP   G P   PPPG+ PPPP
Sbjct: 701 PPPPPPLPNSPAPPNPGGPPPAPPPPGLAPPPP 733


>gi|42544123 splicing factor 1 isoform 3 [Homo sapiens]
          Length = 548

 Score = 61.6 bits (148), Expect = 5e-10
 Identities = 61/215 (28%), Positives = 79/215 (36%), Gaps = 39/215 (18%)

Query: 41  ILCDCDEFRKIKPKNSKQAEREEKRVLGLVLLRGENLVSMTVEGPP-PKDTGIARVPLAG 99
           I  DC   R   P++++   R +K  L L+   GE  V  +V     P  T +A  P   
Sbjct: 288 IASDCKFQRPGDPQSAQDKARMDKEYLSLMAELGEAPVPASVGSTSGPATTPLASAPRPA 347

Query: 100 AAGGPGIGRAAGRGIPAGVPMPQAPAGLAGPVRGV--GGPSQQVMTPQGRGTVAAAAAAA 157
           A        +      +  P   +    + P  G+  GGP      P    +      + 
Sbjct: 348 APANNPPPPSLMSTTQSRPPWMNSGPSESRPYHGMHGGGPGGPGGGPH---SFPHPLPSL 404

Query: 158 TASIAGAPTQY------PPGRGGPPPPMGRGAPPPGMMGPPP------------------ 193
           T    G P Q+      PP    PPPPM +G  PPG  GPPP                  
Sbjct: 405 TGGHGGHPMQHNPNGPPPPWMQPPPPPMNQGPHPPGHHGPPPMDQYLGSTPVGSGVYRLH 464

Query: 194 ---GMRPPMGPPMGIPPGRGTPMGMPPPGMRPPPP 225
              GM PP  PPMG+ P    P   PP G  PPPP
Sbjct: 465 QGKGMMPP--PPMGMMP----PPPPPPSGQPPPPP 493



 Score = 44.7 bits (104), Expect = 7e-05
 Identities = 32/105 (30%), Positives = 40/105 (38%), Gaps = 26/105 (24%)

Query: 149 TVAAAAAAATASIAGAPTQYPPGRGGPPPPM--GRGAPPPGMMGPPPGMRP--------- 197
           +V + +  AT  +A AP    P    PPP +     + PP M   P   RP         
Sbjct: 328 SVGSTSGPATTPLASAPRPAAPANNPPPPSLMSTTQSRPPWMNSGPSESRPYHGMHGGGP 387

Query: 198 --PMGPPMGIP-------------PGRGTPMGMPPPGMRPPPPGM 227
             P G P   P             P +  P G PPP M+PPPP M
Sbjct: 388 GGPGGGPHSFPHPLPSLTGGHGGHPMQHNPNGPPPPWMQPPPPPM 432


>gi|42544125 splicing factor 1 isoform 2 [Homo sapiens]
          Length = 638

 Score = 61.6 bits (148), Expect = 5e-10
 Identities = 61/215 (28%), Positives = 79/215 (36%), Gaps = 39/215 (18%)

Query: 41  ILCDCDEFRKIKPKNSKQAEREEKRVLGLVLLRGENLVSMTVEGPP-PKDTGIARVPLAG 99
           I  DC   R   P++++   R +K  L L+   GE  V  +V     P  T +A  P   
Sbjct: 288 IASDCKFQRPGDPQSAQDKARMDKEYLSLMAELGEAPVPASVGSTSGPATTPLASAPRPA 347

Query: 100 AAGGPGIGRAAGRGIPAGVPMPQAPAGLAGPVRGV--GGPSQQVMTPQGRGTVAAAAAAA 157
           A        +      +  P   +    + P  G+  GGP      P    +      + 
Sbjct: 348 APANNPPPPSLMSTTQSRPPWMNSGPSESRPYHGMHGGGPGGPGGGPH---SFPHPLPSL 404

Query: 158 TASIAGAPTQY------PPGRGGPPPPMGRGAPPPGMMGPPP------------------ 193
           T    G P Q+      PP    PPPPM +G  PPG  GPPP                  
Sbjct: 405 TGGHGGHPMQHNPNGPPPPWMQPPPPPMNQGPHPPGHHGPPPMDQYLGSTPVGSGVYRLH 464

Query: 194 ---GMRPPMGPPMGIPPGRGTPMGMPPPGMRPPPP 225
              GM PP  PPMG+ P    P   PP G  PPPP
Sbjct: 465 QGKGMMPP--PPMGMMP----PPPPPPSGQPPPPP 493



 Score = 45.1 bits (105), Expect = 5e-05
 Identities = 45/174 (25%), Positives = 61/174 (35%), Gaps = 46/174 (26%)

Query: 84  GPPPKDTGIARVPLAGAAGGPGIGRA-AGRGI----PAGVPMPQAPAGLAGPVRGVGGP- 137
           GPPP D  +   P+     G G+ R   G+G+    P G+  P  P     P     GP 
Sbjct: 443 GPPPMDQYLGSTPV-----GSGVYRLHQGKGMMPPPPMGMMPPPPPPPSGQPPPPPSGPL 497

Query: 138 --------------------SQQVMTPQGRGTVAAAAAAATASIAGAPTQYPPGRGGPPP 177
                               +     P  + T     +A T SI     Q       P  
Sbjct: 498 PPWQQQQQQPPPPPPPSSSMASSTPLPWQQNTTTTTTSAGTGSIPPWQQQQAAAAASPGA 557

Query: 178 PMGRGAPPPGMMGPPPGMRPPMGPPMGIPPGRGTPMGMPPPGMRPPPPGMRGLL 231
           P  +G P   M+  PPG++P       +PPG        PP   PPPPG  G++
Sbjct: 558 PQMQGNPT--MVPLPPGVQP------PLPPG-------APPPPPPPPPGSAGMM 596



 Score = 44.7 bits (104), Expect = 7e-05
 Identities = 32/105 (30%), Positives = 40/105 (38%), Gaps = 26/105 (24%)

Query: 149 TVAAAAAAATASIAGAPTQYPPGRGGPPPPM--GRGAPPPGMMGPPPGMRP--------- 197
           +V + +  AT  +A AP    P    PPP +     + PP M   P   RP         
Sbjct: 328 SVGSTSGPATTPLASAPRPAAPANNPPPPSLMSTTQSRPPWMNSGPSESRPYHGMHGGGP 387

Query: 198 --PMGPPMGIP-------------PGRGTPMGMPPPGMRPPPPGM 227
             P G P   P             P +  P G PPP M+PPPP M
Sbjct: 388 GGPGGGPHSFPHPLPSLTGGHGGHPMQHNPNGPPPPWMQPPPPPM 432



 Score = 30.8 bits (68), Expect = 1.0
 Identities = 30/113 (26%), Positives = 36/113 (31%), Gaps = 24/113 (21%)

Query: 85  PPPKDTGIARVPLAGAAGGPGIGRAAGRG-IPAGVPMPQAPAGLAGPVRGVGGPSQQVMT 143
           PPP  +  +  PL           +AG G IP       A A   G  +  G P+   + 
Sbjct: 511 PPPSSSMASSTPLPWQQNTTTTTTSAGTGSIPPWQQQQAAAAASPGAPQMQGNPTMVPLP 570

Query: 144 PQGRGTVAAAAAAATASIAGAPTQYPPGRGGPPPP-----MGRGAPPPGMMGP 191
           P                  G     PPG   PPPP      G   PP G  GP
Sbjct: 571 P------------------GVQPPLPPGAPPPPPPPPPGSAGMMIPPRGGDGP 605


>gi|42544130 splicing factor 1 isoform 1 [Homo sapiens]
          Length = 639

 Score = 61.6 bits (148), Expect = 5e-10
 Identities = 61/215 (28%), Positives = 79/215 (36%), Gaps = 39/215 (18%)

Query: 41  ILCDCDEFRKIKPKNSKQAEREEKRVLGLVLLRGENLVSMTVEGPP-PKDTGIARVPLAG 99
           I  DC   R   P++++   R +K  L L+   GE  V  +V     P  T +A  P   
Sbjct: 288 IASDCKFQRPGDPQSAQDKARMDKEYLSLMAELGEAPVPASVGSTSGPATTPLASAPRPA 347

Query: 100 AAGGPGIGRAAGRGIPAGVPMPQAPAGLAGPVRGV--GGPSQQVMTPQGRGTVAAAAAAA 157
           A        +      +  P   +    + P  G+  GGP      P    +      + 
Sbjct: 348 APANNPPPPSLMSTTQSRPPWMNSGPSESRPYHGMHGGGPGGPGGGPH---SFPHPLPSL 404

Query: 158 TASIAGAPTQY------PPGRGGPPPPMGRGAPPPGMMGPPP------------------ 193
           T    G P Q+      PP    PPPPM +G  PPG  GPPP                  
Sbjct: 405 TGGHGGHPMQHNPNGPPPPWMQPPPPPMNQGPHPPGHHGPPPMDQYLGSTPVGSGVYRLH 464

Query: 194 ---GMRPPMGPPMGIPPGRGTPMGMPPPGMRPPPP 225
              GM PP  PPMG+ P    P   PP G  PPPP
Sbjct: 465 QGKGMMPP--PPMGMMP----PPPPPPSGQPPPPP 493



 Score = 54.7 bits (130), Expect = 7e-08
 Identities = 45/146 (30%), Positives = 52/146 (35%), Gaps = 28/146 (19%)

Query: 85  PPPKDTGIARVPLAGAAGGPGIGRAAGRG-IPAGVPMPQAPAGLAGPVRGVGGPSQQVMT 143
           PPP  +  +  PL           +AG G IP       A A   G  +  G P+   + 
Sbjct: 511 PPPSSSMASSTPLPWQQNTTTTTTSAGTGSIPPWQQQQAAAAASPGAPQMQGNPTMVPLP 570

Query: 144 PQGRGTVAAAAAAATASIAGAPTQYPPGRGGPPPPMGRGAPPPGMMG----PPPGMRPPM 199
           P                  G     PPG   PPPP     PPPG  G    PPP   PPM
Sbjct: 571 P------------------GVQPPLPPGAPPPPPP-----PPPGSAGMMYAPPPPPPPPM 607

Query: 200 GPPMGIPPGRGTPMGMPPPGMRPPPP 225
            P   +        GMPP GM P PP
Sbjct: 608 DPSNFVTMMGMGVAGMPPFGMPPAPP 633



 Score = 53.1 bits (126), Expect = 2e-07
 Identities = 60/203 (29%), Positives = 71/203 (34%), Gaps = 70/203 (34%)

Query: 84  GPPPKDTGIARVPLAGAAGGPGIGRA-AGRGI----PAGVPMPQAPAGLAGPVRGVGGP- 137
           GPPP D  +   P+     G G+ R   G+G+    P G+  P  P     P     GP 
Sbjct: 443 GPPPMDQYLGSTPV-----GSGVYRLHQGKGMMPPPPMGMMPPPPPPPSGQPPPPPSGPL 497

Query: 138 ----SQQVMTPQ---------------------------GRGTV--------AAAAAAAT 158
                QQ   P                            G G++        AAAA+   
Sbjct: 498 PPWQQQQQQPPPPPPPSSSMASSTPLPWQQNTTTTTTSAGTGSIPPWQQQQAAAAASPGA 557

Query: 159 ASIAGAPTQYP--PG------RGGPPPPMGRGAPPPG----MMGPPPGMRPPMGPP---- 202
             + G PT  P  PG       G PPPP     PPPG    M  PPP   PPM P     
Sbjct: 558 PQMQGNPTMVPLPPGVQPPLPPGAPPPP---PPPPPGSAGMMYAPPPPPPPPMDPSNFVT 614

Query: 203 -MGIPPGRGTPMGMPPPGMRPPP 224
            MG+      P GMPP    PPP
Sbjct: 615 MMGMGVAGMPPFGMPPAPPPPPP 637



 Score = 44.7 bits (104), Expect = 7e-05
 Identities = 32/105 (30%), Positives = 40/105 (38%), Gaps = 26/105 (24%)

Query: 149 TVAAAAAAATASIAGAPTQYPPGRGGPPPPM--GRGAPPPGMMGPPPGMRP--------- 197
           +V + +  AT  +A AP    P    PPP +     + PP M   P   RP         
Sbjct: 328 SVGSTSGPATTPLASAPRPAAPANNPPPPSLMSTTQSRPPWMNSGPSESRPYHGMHGGGP 387

Query: 198 --PMGPPMGIP-------------PGRGTPMGMPPPGMRPPPPGM 227
             P G P   P             P +  P G PPP M+PPPP M
Sbjct: 388 GGPGGGPHSFPHPLPSLTGGHGGHPMQHNPNGPPPPWMQPPPPPM 432


>gi|126352608 elastin isoform e precursor [Homo sapiens]
          Length = 705

 Score = 61.2 bits (147), Expect = 7e-10
 Identities = 59/163 (36%), Positives = 70/163 (42%), Gaps = 20/163 (12%)

Query: 86  PPKDTGIARVPLAGAAGG---PGIGRAA-GRGI--PAGVPMPQAPAGLAGPVRGVGGPSQ 139
           P +  G+      G  GG   PG G  A G G   P G P+   P GLAG   G G  + 
Sbjct: 23  PSRPGGVPGAIPGGVPGGVFYPGAGLGALGGGALGPGGKPLKPVPGGLAGAGLGAGLGAF 82

Query: 140 QVMTPQGR---GTVAAAAAAATASIAGAPTQYPPGRGGPPPPMGRGAPPPGMMGPPPGMR 196
             +T  G    G VA AAAA  A+ AGA     PG GG     G   P PG  G  PG  
Sbjct: 83  PAVTFPGALVPGGVADAAAAYKAAKAGAGLGGVPGVGGLGVSAGAVVPQPG-AGVKPGKV 141

Query: 197 PPMGPPMGIP---------PGRGTPMGMPP-PGMRPPPPGMRG 229
           P +G P   P         PG G   G+P   G++P  PG+ G
Sbjct: 142 PGVGLPGVYPGGVLPGARFPGVGVLPGVPTGAGVKPKAPGVGG 184



 Score = 50.8 bits (120), Expect = 1e-06
 Identities = 51/136 (37%), Positives = 65/136 (47%), Gaps = 26/136 (19%)

Query: 91  GIARVPL--AGAAGGPGIGRAAGRGIP--AGVPMPQAPAGLAGPVRGVGGPSQQVMTPQG 146
           G+  +P    GA G PG G   G GIP  AGVP      G+ G V GVGG     ++P+ 
Sbjct: 390 GVGGIPTYGVGAGGFPGFGVGVG-GIPGVAGVP------GVGG-VPGVGGVPGVGISPE- 440

Query: 147 RGTVAAAAAAATASIAGAPTQYPPGRGGPPPPMGRGAPPPGMMGPPPGMRPPMG--PPMG 204
               A AAAAA A+  G      PG G  P   G G  P   + P  G+ P +G  P +G
Sbjct: 441 ----AQAAAAAKAAKYGLV----PGVGVAP---GVGVAPGVGVAPGVGLAPGVGVAPGVG 489

Query: 205 IPPGRGTPMGMPPPGM 220
           + PG G   G+ P G+
Sbjct: 490 VAPGVGVAPGIGPGGV 505



 Score = 50.4 bits (119), Expect = 1e-06
 Identities = 51/130 (39%), Positives = 63/130 (48%), Gaps = 31/130 (23%)

Query: 98  AGAAGG-PGIGRAAGRGIPAGVPMPQAPAGLAGPVRGVGGPSQQVMTPQGRGTVAAAAAA 156
           AGAAG  PG+G   G G+P          G+ G + G+GG +       G GT AAAAAA
Sbjct: 268 AGAAGVLPGVG---GAGVP----------GVPGAIPGIGGIA-------GVGTPAAAAAA 307

Query: 157 ATASIAGAPTQYPPGRGGPPPPMGRGAPPPGMMGPPPGMRPPMG-PPMGIP--PGRGTPM 213
           A A+ A    +Y    G  P   G G   PG++G P    P +G P  GIP  PG G P 
Sbjct: 308 AAAAKA---AKYGAAAGLVPGGPGFG---PGVVGVPGAGVPGVGVPGAGIPVVPGAGIP- 360

Query: 214 GMPPPGMRPP 223
           G   PG+  P
Sbjct: 361 GAAVPGVVSP 370



 Score = 46.2 bits (108), Expect = 2e-05
 Identities = 45/135 (33%), Positives = 54/135 (40%), Gaps = 22/135 (16%)

Query: 98  AGAAGGPGIGRAAGRGIPAGVPMPQAPAGLA-GPVRGVGGPSQQVMTPQGRGTVAAAAAA 156
           AG  G PG+G   G G+ AG  +PQ  AG+  G V GVG P          G +  A   
Sbjct: 110 AGLGGVPGVG---GLGVSAGAVVPQPGAGVKPGKVPGVGLPGVYP-----GGVLPGARFP 161

Query: 157 ATASIAGAPTQYPPGRGGPPPPMGRGAPPPGMMGPPPGMRPPMGPPMG-------IPPGR 209
               + G PT    G G  P   G G    G+ G  P   P  G P+G       +P G 
Sbjct: 162 GVGVLPGVPT----GAGVKPKAPGVGGAFAGIPGVGPFGGPQPGVPLGYPIKAPKLPGGY 217

Query: 210 GTP--MGMPPPGMRP 222
           G P   G  P G  P
Sbjct: 218 GLPYTTGKLPYGYGP 232



 Score = 43.5 bits (101), Expect = 2e-04
 Identities = 41/117 (35%), Positives = 51/117 (43%), Gaps = 15/117 (12%)

Query: 91  GIARVPLAGAAGGPGIGRAAGRGIPAGVPMPQAPAGLAGPVRGVG-GPSQQVMTPQGRGT 149
           G+   P  G A  PG+G A G G+  GV          G   GVG  P   V    G G 
Sbjct: 457 GVGVAPGVGVA--PGVGVAPGVGLAPGV----------GVAPGVGVAPGVGVAPGIGPGG 504

Query: 150 VAAAAAAATASIAGAPTQYPPGRGGPPPPMGRGAPPPGMMGPPPGMRPPMGPPMGIP 206
           VAAAA +A    A A  +   G G   P +G G   PG +G   G+ P +G   G+P
Sbjct: 505 VAAAAKSAAKVAAKAQLRAAAGLGAGIPGLGVGVGVPG-LGVGAGV-PGLGVGAGVP 559



 Score = 42.7 bits (99), Expect = 3e-04
 Identities = 45/133 (33%), Positives = 55/133 (41%), Gaps = 29/133 (21%)

Query: 81  TVEGPPPKDTGI----ARVPLAGAAGGPGIGRAAGRGI-----PAGVPMPQA-------- 123
           T  G  PK  G+    A +P  G  GGP  G   G  I     P G  +P          
Sbjct: 171 TGAGVKPKAPGVGGAFAGIPGVGPFGGPQPGVPLGYPIKAPKLPGGYGLPYTTGKLPYGY 230

Query: 124 -PAGLAGPVRGVGGPSQQVMTPQGRGTVAAAAAAATASIAGAPTQYPPGRGGPPPPMGRG 182
            P G+AG     G P     T  G G  AAAAAAA A+      ++  G  G  P +G G
Sbjct: 231 GPGGVAGAAGKAGYP-----TGTGVGPQAAAAAAAKAA-----AKFGAGAAGVLPGVG-G 279

Query: 183 APPPGMMGPPPGM 195
           A  PG+ G  PG+
Sbjct: 280 AGVPGVPGAIPGI 292



 Score = 37.0 bits (84), Expect = 0.014
 Identities = 42/117 (35%), Positives = 50/117 (42%), Gaps = 13/117 (11%)

Query: 102 GGPGIGRAAGRGIP-AGVPMPQAPAGLAGPVRGVGGPSQQ---VMTPQGRGTVAAAAAAA 157
           GGPG G     G+P AGVP    P      V G G P      V++P+     AA AA  
Sbjct: 325 GGPGFGPGV-VGVPGAGVPGVGVPGAGIPVVPGAGIPGAAVPGVVSPEAAAKAAAKAAKY 383

Query: 158 TA----SIAGAPTQYPPGRGG-PPPPMGRGAPPPGMMGPPPGMRPPMG--PPMGIPP 207
            A     + G PT Y  G GG P   +G G  P     P  G  P +G  P +GI P
Sbjct: 384 GARPGVGVGGIPT-YGVGAGGFPGFGVGVGGIPGVAGVPGVGGVPGVGGVPGVGISP 439



 Score = 35.4 bits (80), Expect = 0.042
 Identities = 37/102 (36%), Positives = 44/102 (43%), Gaps = 15/102 (14%)

Query: 93  ARVPLAGAAG-GPGIGRAAGRGIPAGVPMPQAPAGLAGPVRGVGGPSQQVMTPQGRGTVA 151
           A+  L  AAG G GI    G G+  GVP     AG+ G   G G P        G G V 
Sbjct: 517 AKAQLRAAAGLGAGI---PGLGVGVGVPGLGVGAGVPGLGVGAGVP--------GFGAVP 565

Query: 152 AAAAAATASIAGAPTQYPPGRGGPPPPMGRGAPPPGMMGPPP 193
            A AAA A+  GA     PG  G    +G    P G++G  P
Sbjct: 566 GALAAAKAAKYGAAV---PGVLGGLGALGGVGIPGGVVGAGP 604



 Score = 32.3 bits (72), Expect = 0.35
 Identities = 41/126 (32%), Positives = 48/126 (38%), Gaps = 29/126 (23%)

Query: 84  GPPPKDTGIARVPLAGAAGGPGIGRAAGRGIPAGVPMPQAPA---------------GLA 128
           G P    G+    L   AG PG+G   G G+P    +P A A               G  
Sbjct: 530 GIPGLGVGVGVPGLGVGAGVPGLG--VGAGVPGFGAVPGALAAAKAAKYGAAVPGVLGGL 587

Query: 129 GPVRGVGGPSQQVMTPQGRGTVAAAAAAATAS------IAGAPTQYPPGRG--GPPPPMG 180
           G + GVG P   V    G G  AAAAAA  A+      + GA      G G  G P   G
Sbjct: 588 GALGGVGIPGGVV----GAGPAAAAAAAKAAAKAAQFGLVGAAGLGGLGVGGLGVPGVGG 643

Query: 181 RGAPPP 186
            G  PP
Sbjct: 644 LGGIPP 649


  Database: hs.faa
    Posted date:  Aug 4, 2009  4:42 PM
  Number of letters in database: 18,247,518
  Number of sequences in database:  37,866
  
Lambda     K      H
   0.318    0.141    0.448 

Gapped
Lambda     K      H
   0.267   0.0410    0.140 


Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Hits to DB: 15,763,959
Number of Sequences: 37866
Number of extensions: 1427885
Number of successful extensions: 34605
Number of sequences better than 10.0: 30
Number of HSP's better than 10.0 without gapping: 782
Number of HSP's successfully gapped in prelim test: 1700
Number of HSP's that attempted gapping in prelim test: 9453
Number of HSP's gapped (non-prelim): 11323
length of query: 231
length of database: 18,247,518
effective HSP length: 99
effective length of query: 132
effective length of database: 14,498,784
effective search space: 1913839488
effective search space used: 1913839488
T: 11
A: 40
X1: 16 ( 7.3 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 41 (21.6 bits)
S2: 60 (27.7 bits)

Search results were obtained with NCBI BLAST and RefSeq entries.


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Guide to the Human Genome
Copyright © 2010 by Stewart Scherer. All rights reserved.

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