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Search of human proteins with 4507041
BLASTP 2.2.11 [Jun-05-2005]
Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer,
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997),
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs", Nucleic Acids Res. 25:3389-3402.
Query= gi|4507041 solute carrier family 6 (neurotransmitter
transporter, dopamine), member 3 [Homo sapiens]
(620 letters)
Database: hs.faa
37,866 sequences; 18,247,518 total letters
Searching..................................................done
Score E
Sequences producing significant alignments: (bits) Value
gi|4507041 solute carrier family 6 (neurotransmitter transporter... 1262 0.0
gi|4557046 solute carrier family 6 member 2 [Homo sapiens] 850 0.0
gi|4507043 solute carrier family 6 member 4 [Homo sapiens] 612 e-175
gi|188528618 solute carrier family 6 (neurotransmitter transport... 542 e-154
gi|92859670 solute carrier family 6 (neurotransmitter transporte... 520 e-147
gi|171184408 solute carrier family 6 (neurotransmitter transport... 515 e-146
gi|171184406 solute carrier family 6 (neurotransmitter transport... 515 e-146
gi|171184404 solute carrier family 6 (neurotransmitter transport... 515 e-146
gi|134304856 solute carrier family 6, member 7 [Homo sapiens] 509 e-144
gi|21361581 solute carrier family 6 (neurotransmitter transporte... 507 e-143
gi|5032097 solute carrier family 6 member 8 isoform 1 [Homo sapi... 506 e-143
gi|197276623 solute carrier family 6 (neurotransmitter transport... 501 e-142
gi|54607094 solute carrier family 6 (neurotransmitter transporte... 501 e-142
gi|7657587 solute carrier family 6 (neurotransmitter transporter... 493 e-139
gi|218563756 solute carrier family 6 member 8 isoform 2 [Homo sa... 487 e-137
gi|67782313 solute carrier family 6 member 9 isoform 1 [Homo sap... 478 e-135
gi|67782317 solute carrier family 6 member 9 isoform 3 [Homo sap... 477 e-134
gi|67782315 solute carrier family 6 member 9 isoform 2 [Homo sap... 477 e-134
gi|6005715 solute carrier family 6 (amino acid transporter), mem... 476 e-134
gi|218563758 solute carrier family 6 member 8 isoform 3 [Homo sa... 407 e-113
gi|51468073 solute carrier family 6, member 19 [Homo sapiens] 360 2e-99
gi|194018524 solute carrier family 6, member 18 [Homo sapiens] 352 4e-97
gi|33354281 solute carrier family 6, member 15 isoform 1 [Homo s... 328 1e-89
gi|11181770 solute carrier family 6, member 20 isoform 1 [Homo s... 284 2e-76
gi|58219014 solute carrier family 6, member 17 [Homo sapiens] 273 3e-73
gi|226437581 solute carrier family 6, member 15 isoform 3 [Homo ... 260 3e-69
gi|12408638 solute carrier family 6, member 20 isoform 2 [Homo s... 237 3e-62
gi|197276625 solute carrier family 6 (neurotransmitter transport... 179 5e-45
gi|21361693 solute carrier family 6, member 15 isoform 2 [Homo s... 164 2e-40
gi|55749589 solute carrier family 6, member 16 [Homo sapiens] 163 4e-40
>gi|4507041 solute carrier family 6 (neurotransmitter transporter,
dopamine), member 3 [Homo sapiens]
Length = 620
Score = 1262 bits (3266), Expect = 0.0
Identities = 620/620 (100%), Positives = 620/620 (100%)
Query: 1 MSKSKCSVGLMSSVVAPAKEPNAVGPKEVELILVKEQNGVQLTSSTLTNPRQSPVEAQDR 60
MSKSKCSVGLMSSVVAPAKEPNAVGPKEVELILVKEQNGVQLTSSTLTNPRQSPVEAQDR
Sbjct: 1 MSKSKCSVGLMSSVVAPAKEPNAVGPKEVELILVKEQNGVQLTSSTLTNPRQSPVEAQDR 60
Query: 61 ETWGKKIDFLLSVIGFAVDLANVWRFPYLCYKNGGGAFLVPYLLFMVIAGMPLFYMELAL 120
ETWGKKIDFLLSVIGFAVDLANVWRFPYLCYKNGGGAFLVPYLLFMVIAGMPLFYMELAL
Sbjct: 61 ETWGKKIDFLLSVIGFAVDLANVWRFPYLCYKNGGGAFLVPYLLFMVIAGMPLFYMELAL 120
Query: 121 GQFNREGAAGVWKICPILKGVGFTVILISLYVGFFYNVIIAWALHYLFSSFTTELPWIHC 180
GQFNREGAAGVWKICPILKGVGFTVILISLYVGFFYNVIIAWALHYLFSSFTTELPWIHC
Sbjct: 121 GQFNREGAAGVWKICPILKGVGFTVILISLYVGFFYNVIIAWALHYLFSSFTTELPWIHC 180
Query: 181 NNSWNSPNCSDAHPGDSSGDSSGLNDTFGTTPAAEYFERGVLHLHQSHGIDDLGPPRWQL 240
NNSWNSPNCSDAHPGDSSGDSSGLNDTFGTTPAAEYFERGVLHLHQSHGIDDLGPPRWQL
Sbjct: 181 NNSWNSPNCSDAHPGDSSGDSSGLNDTFGTTPAAEYFERGVLHLHQSHGIDDLGPPRWQL 240
Query: 241 TACLVLVIVLLYFSLWKGVKTSGKVVWITATMPYVVLTALLLRGVTLPGAIDGIRAYLSV 300
TACLVLVIVLLYFSLWKGVKTSGKVVWITATMPYVVLTALLLRGVTLPGAIDGIRAYLSV
Sbjct: 241 TACLVLVIVLLYFSLWKGVKTSGKVVWITATMPYVVLTALLLRGVTLPGAIDGIRAYLSV 300
Query: 301 DFYRLCEASVWIDAATQVCFSLGVGFGVLIAFSSYNKFTNNCYRDAIVTTSINSLTSFSS 360
DFYRLCEASVWIDAATQVCFSLGVGFGVLIAFSSYNKFTNNCYRDAIVTTSINSLTSFSS
Sbjct: 301 DFYRLCEASVWIDAATQVCFSLGVGFGVLIAFSSYNKFTNNCYRDAIVTTSINSLTSFSS 360
Query: 361 GFVVFSFLGYMAQKHSVPIGDVAKDGPGLIFIIYPEAIATLPLSSAWAVVFFIMLLTLGI 420
GFVVFSFLGYMAQKHSVPIGDVAKDGPGLIFIIYPEAIATLPLSSAWAVVFFIMLLTLGI
Sbjct: 361 GFVVFSFLGYMAQKHSVPIGDVAKDGPGLIFIIYPEAIATLPLSSAWAVVFFIMLLTLGI 420
Query: 421 DSAMGGMESVITGLIDEFQLLHRHRELFTLFIVLATFLLSLFCVTNGGIYVFTLLDHFAA 480
DSAMGGMESVITGLIDEFQLLHRHRELFTLFIVLATFLLSLFCVTNGGIYVFTLLDHFAA
Sbjct: 421 DSAMGGMESVITGLIDEFQLLHRHRELFTLFIVLATFLLSLFCVTNGGIYVFTLLDHFAA 480
Query: 481 GTSILFGVLIEAIGVAWFYGVGQFSDDIQQMTGQRPSLYWRLCWKLVSPCFLLFVVVVSI 540
GTSILFGVLIEAIGVAWFYGVGQFSDDIQQMTGQRPSLYWRLCWKLVSPCFLLFVVVVSI
Sbjct: 481 GTSILFGVLIEAIGVAWFYGVGQFSDDIQQMTGQRPSLYWRLCWKLVSPCFLLFVVVVSI 540
Query: 541 VTFRPPHYGAYIFPDWANALGWVIATSSMAMVPIYAAYKFCSLPGSFREKLAYAIAPEKD 600
VTFRPPHYGAYIFPDWANALGWVIATSSMAMVPIYAAYKFCSLPGSFREKLAYAIAPEKD
Sbjct: 541 VTFRPPHYGAYIFPDWANALGWVIATSSMAMVPIYAAYKFCSLPGSFREKLAYAIAPEKD 600
Query: 601 RELVDRGEVRQFTLRHWLKV 620
RELVDRGEVRQFTLRHWLKV
Sbjct: 601 RELVDRGEVRQFTLRHWLKV 620
>gi|4557046 solute carrier family 6 member 2 [Homo sapiens]
Length = 617
Score = 850 bits (2195), Expect = 0.0
Identities = 416/620 (67%), Positives = 491/620 (79%), Gaps = 18/620 (2%)
Query: 11 MSSVVAPAKEPNAVGP-------KEVELILVKEQNGVQLTSSTLTNPRQSPVEAQDRETW 63
M+ V P GP K EL++VKE+NGVQ L PR +AQ RETW
Sbjct: 6 MNPQVQPENNGADTGPEQPLRARKTAELLVVKERNGVQC----LLAPRDG--DAQPRETW 59
Query: 64 GKKIDFLLSVIGFAVDLANVWRFPYLCYKNGGGAFLVPYLLFMVIAGMPLFYMELALGQF 123
GKKIDFLLSV+GFAVDLANVWRFPYLCYKNGGGAFL+PY LF++IAGMPLFYMELALGQ+
Sbjct: 60 GKKIDFLLSVVGFAVDLANVWRFPYLCYKNGGGAFLIPYTLFLIIAGMPLFYMELALGQY 119
Query: 124 NREGAAGVWKICPILKGVGFTVILISLYVGFFYNVIIAWALHYLFSSFTTELPWIHCNNS 183
NREGAA VWKICP KGVG+ VILI+LYVGF+YNVIIAW+L+YLFSSFT LPW C ++
Sbjct: 120 NREGAATVWKICPFFKGVGYAVILIALYVGFYYNVIIAWSLYYLFSSFTLNLPWTDCGHT 179
Query: 184 WNSPNCSDAHPGDSSGDSSGLNDTFGT---TPAAEYFERGVLHLHQSHGIDDLGPPRWQL 240
WNSPNC+D P +G G + + TPAAE++ERGVLHLH+S GI D+G P+WQL
Sbjct: 180 WNSPNCTD--PKLLNGSVLGNHTKYSKYKFTPAAEFYERGVLHLHESSGIHDIGLPQWQL 237
Query: 241 TACLVLVIVLLYFSLWKGVKTSGKVVWITATMPYVVLTALLLRGVTLPGAIDGIRAYLSV 300
CL++V+++LYFSLWKGVKTSGKVVWITAT+PY VL LL+ GVTLPGA +GI AYL +
Sbjct: 238 LLCLMVVVIVLYFSLWKGVKTSGKVVWITATLPYFVLFVLLVHGVTLPGASNGINAYLHI 297
Query: 301 DFYRLCEASVWIDAATQVCFSLGVGFGVLIAFSSYNKFTNNCYRDAIVTTSINSLTSFSS 360
DFYRL EA+VWIDAATQ+ FSLG GFGVLIAF+SYNKF NNCYRDA++T+SIN +TSF S
Sbjct: 298 DFYRLKEATVWIDAATQIFFSLGAGFGVLIAFASYNKFDNNCYRDALLTSSINCITSFVS 357
Query: 361 GFVVFSFLGYMAQKHSVPIGDVAKDGPGLIFIIYPEAIATLPLSSAWAVVFFIMLLTLGI 420
GF +FS LGYMA +H V I DVA +G GL+FI+YPEAI+TL S+ WAVVFF+MLL LG+
Sbjct: 358 GFAIFSILGYMAHEHKVNIEDVATEGAGLVFILYPEAISTLSGSTFWAVVFFVMLLALGL 417
Query: 421 DSAMGGMESVITGLIDEFQLLHRHRELFTLFIVLATFLLSLFCVTNGGIYVFTLLDHFAA 480
DS+MGGME+VITGL D+FQ+L RHR+LFT + +TFLL+LFC+T GGIYV TLLD FAA
Sbjct: 418 DSSMGGMEAVITGLADDFQVLKRHRKLFTFGVTFSTFLLALFCITKGGIYVLTLLDTFAA 477
Query: 481 GTSILFGVLIEAIGVAWFYGVGQFSDDIQQMTGQRPSLYWRLCWKLVSPCFLLFVVVVSI 540
GTSILF VL+EAIGV+WFYGV +FS+DIQQM G RP LYWRLCWK VSP FLLFVVVVSI
Sbjct: 478 GTSILFAVLMEAIGVSWFYGVDRFSNDIQQMMGFRPGLYWRLCWKFVSPAFLLFVVVVSI 537
Query: 541 VTFRPPHYGAYIFPDWANALGWVIATSSMAMVPIYAAYKFCSLPGSFREKLAYAIAPEKD 600
+ F+P Y YIFP WAN +GW IA SSM +VPIY YKF S GS E+LAY I PE +
Sbjct: 538 INFKPLTYDDYIFPPWANWVGWGIALSSMVLVPIYVIYKFLSTQGSLWERLAYGITPENE 597
Query: 601 RELVDRGEVRQFTLRHWLKV 620
LV + ++RQF L+HWL +
Sbjct: 598 HHLVAQRDIRQFQLQHWLAI 617
>gi|4507043 solute carrier family 6 member 4 [Homo sapiens]
Length = 630
Score = 612 bits (1577), Expect = e-175
Identities = 287/577 (49%), Positives = 404/577 (70%), Gaps = 13/577 (2%)
Query: 37 QNGVQLTSSTLTNPRQSPVEAQDRETWGKKIDFLLSVIGFAVDLANVWRFPYLCYKNGGG 96
++ + T++TL + + +RETWGKK+DFLLSVIG+AVDL NVWRFPY+CY+NGGG
Sbjct: 60 RHSIPATTTTLV----AELHQGERETWGKKVDFLLSVIGYAVDLGNVWRFPYICYQNGGG 115
Query: 97 AFLVPYLLFMVIAGMPLFYMELALGQFNREGAAGVW-KICPILKGVGFTVILISLYVGFF 155
AFL+PY + + G+PLFYMELALGQ++R G +W KICPI KG+G+ + +I+ Y+ +
Sbjct: 116 AFLLPYTIMAIFGGIPLFYMELALGQYHRNGCISIWRKICPIFKGIGYAICIIAFYIASY 175
Query: 156 YNVIIAWALHYLFSSFTTELPWIHCNNSWNSPNCSDAHPGDSSGDSSGLNDTFGTTPAAE 215
YN I+AWAL+YL SSFT +LPW C NSWN+ NC++ D+ + T+PA E
Sbjct: 176 YNTIMAWALYYLISSFTDQLPWTSCKNSWNTGNCTNYFSEDNITWT-----LHSTSPAEE 230
Query: 216 YFERGVLHLHQSHGIDDLGPPRWQLTACLVLVIVLLYFSLWKGVKTSGKVVWITATMPYV 275
++ R VL +H+S G+ DLG WQL C++L+ ++YFS+WKGVKTSGKVVW+TAT PY+
Sbjct: 231 FYTRHVLQIHRSKGLQDLGGISWQLALCIMLIFTVIYFSIWKGVKTSGKVVWVTATFPYI 290
Query: 276 VLTALLLRGVTLPGAIDGIRAYLSVDFYRLCEASVWIDAATQVCFSLGVGFGVLIAFSSY 335
+L+ LL+RG TLPGA G+ YL ++ +L E VWIDAA Q+ FSLG GFGVL+AF+SY
Sbjct: 291 ILSVLLVRGATLPGAWRGVLFYLKPNWQKLLETGVWIDAAAQIFFSLGPGFGVLLAFASY 350
Query: 336 NKFTNNCYRDAIVTTSINSLTSFSSGFVVFSFLGYMAQKHSVPIGDVAKD-GPGLIFIIY 394
NKF NNCY+DA+VT+ +N +TSF SGFV+F+ LGYMA+ + + +VAKD GP L+FI Y
Sbjct: 351 NKFNNNCYQDALVTSVVNCMTSFVSGFVIFTVLGYMAEMRNEDVSEVAKDAGPSLLFITY 410
Query: 395 PEAIATLPLSSAWAVVFFIMLLTLGIDSAMGGMESVITGLIDEF-QLLHRHRELFTLFIV 453
EAIA +P S+ +A++FF+ML+TLG+DS G+E VIT ++DEF + + RE F L +V
Sbjct: 411 AEAIANMPASTFFAIIFFLMLITLGLDSTFAGLEGVITAVLDEFPHVWAKRRERFVLAVV 470
Query: 454 LATFLLSLFCVTNGGIYVFTLLDHFAAGTSILFGVLIEAIGVAWFYGVGQFSDDIQQMTG 513
+ F SL +T GG YV LL+ +A G ++L LIEA+ V+WFYG+ QF D+++M G
Sbjct: 471 ITCFFGSLVTLTFGGAYVVKLLEEYATGPAVLTVALIEAVAVSWFYGITQFCRDVKEMLG 530
Query: 514 QRPSLYWRLCWKLVSPCFLLFVVVVSIVTFRPPHYGAYIFPDWANALGWVIATSSMAMVP 573
P +WR+CW +SP FLLF++ +++ Y +P W+ LG+ I TSS +P
Sbjct: 531 FSPGWFWRICWVAISPLFLLFIICSFLMSPPQLRLFQYNYPYWSIILGYCIGTSSFICIP 590
Query: 574 IYAAYKFCSLPGSFREKLAYAIAPEKDRELVDRGEVR 610
Y AY+ PG+F+E++ +I PE E + G++R
Sbjct: 591 TYIAYRLIITPGTFKERIIKSITPETPTE-IPCGDIR 626
>gi|188528618 solute carrier family 6 (neurotransmitter transporter,
GABA), member 1 [Homo sapiens]
Length = 599
Score = 542 bits (1397), Expect = e-154
Identities = 256/553 (46%), Positives = 364/553 (65%), Gaps = 14/553 (2%)
Query: 51 RQSPVEAQDRETWGKKIDFLLSVIGFAVDLANVWRFPYLCYKNGGGAFLVPYLLFMVIAG 110
++ + DR+TW + DFL+S +G+A+ L NVWRFPYLC KNGGGAFL+PY L ++ AG
Sbjct: 35 QKKAADLPDRDTWKGRFDFLMSCVGYAIGLGNVWRFPYLCGKNGGGAFLIPYFLTLIFAG 94
Query: 111 MPLFYMELALGQFNREGAAGVWKICPILKGVGFTVILISLYVGFFYNVIIAWALHYLFSS 170
+PLF +E +LGQ+ G GVWK+ P+ KGVG ++S ++ +Y VII+WA++YL++S
Sbjct: 95 VPLFLLECSLGQYTSIGGLGVWKLAPMFKGVGLAAAVLSFWLNIYYIVIISWAIYYLYNS 154
Query: 171 FTTELPWIHCNNSWNSPNCSDAHPGDSSGDSSGLNDTFGTTPAAEYFERGVLHLHQ-SHG 229
FTT LPW C+N WN+ C + S +N T T+ E++ER ++HQ + G
Sbjct: 155 FTTTLPWKQCDNPWNTDRCFSNY--------SMVNTTNMTSAVVEFWER---NMHQMTDG 203
Query: 230 IDDLGPPRWQLTACLVLVIVLLYFSLWKGVKTSGKVVWITATMPYVVLTALLLRGVTLPG 289
+D G RW L L + +L+YF +WKGV +GKVV+ +AT PY++L L RGVTLPG
Sbjct: 204 LDKPGQIRWPLAITLAIAWILVYFCIWKGVGWTGKVVYFSATYPYIMLIILFFRGVTLPG 263
Query: 290 AIDGIRAYLSVDFYRLCEASVWIDAATQVCFSLGVGFGVLIAFSSYNKFTNNCYRDAIVT 349
A +GI Y++ +F +L ++ VW+DAATQ+ FS G+G G LIA SYN F NN YRD+I+
Sbjct: 264 AKEGILFYITPNFRKLSDSEVWLDAATQIFFSYGLGLGSLIALGSYNSFHNNVYRDSIIV 323
Query: 350 TSINSLTSFSSGFVVFSFLGYMAQKHSVPIGDVAKDGPGLIFIIYPEAIATLPLSSAWAV 409
INS TS +GFV+FS +G+MA I DVA GPGL F+ YPEA+ LP+S WA+
Sbjct: 324 CCINSCTSMFAGFVIFSIVGFMAHVTKRSIADVAASGPGLAFLAYPEAVTQLPISPLWAI 383
Query: 410 VFFIMLLTLGIDSAMGGMESVITGLIDEF-QLLHRHRELFTLFIVLATFLLSLFCVTNGG 468
+FF MLL LGIDS +E IT L+DE+ +LL RELF + + ++L+ L +T GG
Sbjct: 384 LFFSMLLMLGIDSQFCTVEGFITALVDEYPRLLRNRRELFIAAVCIISYLIGLSNITQGG 443
Query: 469 IYVFTLLDHF-AAGTSILFGVLIEAIGVAWFYGVGQFSDDIQQMTGQRPSLYWRLCWKLV 527
IYVF L D++ A+G S+LF V E + ++WFYGV +F D+IQ+M G RP ++W+LCW
Sbjct: 444 IYVFKLFDYYSASGMSLLFLVFFECVSISWFYGVNRFYDNIQEMVGSRPCIWWKLCWSFF 503
Query: 528 SPCFLLFVVVVSIVTFRPPHYGAYIFPDWANALGWVIATSSMAMVPIYAAYKFCSLPGSF 587
+P + V + S V P G Y+FP W +GW++A SSM ++P Y AY F +L GS
Sbjct: 504 TPIIVAGVFIFSAVQMTPLTMGNYVFPKWGQGVGWLMALSSMVLIPGYMAYMFLTLKGSL 563
Query: 588 REKLAYAIAPEKD 600
++++ + P +D
Sbjct: 564 KQRIQVMVQPSED 576
>gi|92859670 solute carrier family 6 (neurotransmitter transporter,
glycine), member 5 [Homo sapiens]
Length = 797
Score = 520 bits (1338), Expect = e-147
Identities = 252/574 (43%), Positives = 367/574 (63%), Gaps = 32/574 (5%)
Query: 56 EAQDRETWGKKIDFLLSVIGFAVDLANVWRFPYLCYKNGGGAFLVPYLLFMVIAGMPLFY 115
E + R W K+DF+LS++G+AV L NVWRFPYL ++NGGGAFL+PYL+ + +AG+P+F+
Sbjct: 187 ENKARGNWSSKLDFILSMVGYAVGLGNVWRFPYLAFQNGGGAFLIPYLMMLALAGLPIFF 246
Query: 116 MELALGQFNREGAAGVWKICPILKGVGFTVILISLYVGFFYNVIIAWALHYLFSSFTTEL 175
+E++LGQF +G VWK P L+G G +++IS+ + +YNVII + L YLF+SF + L
Sbjct: 247 LEVSLGQFASQGPVSVWKAIPALQGCGIAMLIISVLIAIYYNVIICYTLFYLFASFVSVL 306
Query: 176 PWIHCNNSWNSPNCSDA------------HPGDSSGDS----------------SGLNDT 207
PW CNN WN+P C D HP +S S N T
Sbjct: 307 PWGSCNNPWNTPECKDKTKLLLDSCVISDHPKIQIKNSTFCMTAYPNVTMVNFTSQANKT 366
Query: 208 FGTTPAAEYFERGVLHLHQSHGIDDLGPPRWQLTACLVLVIVLLYFSLWKGVKTSGKVVW 267
F + + EYF+ VL + S GI+ G RW L CL L V++Y SL KG+KTSGKVV+
Sbjct: 367 F-VSGSEEYFKYFVLKI--SAGIEYPGEIRWPLALCLFLAWVIVYASLAKGIKTSGKVVY 423
Query: 268 ITATMPYVVLTALLLRGVTLPGAIDGIRAYLSVDFYRLCEASVWIDAATQVCFSLGVGFG 327
TAT PYVVL LL+RGVTLPGA GI +++ + +L +A+VW DAATQ+ FSL +G
Sbjct: 424 FTATFPYVVLVILLIRGVTLPGAGAGIWYFITPKWEKLTDATVWKDAATQIFFSLSAAWG 483
Query: 328 VLIAFSSYNKFTNNCYRDAIVTTSINSLTSFSSGFVVFSFLGYMAQKHSVPIGDVAKDGP 387
LI SSYNKF NNCYRD ++ T NS TS +GFV+FS +G+MA + V I +VA GP
Sbjct: 484 GLITLSSYNKFHNNCYRDTLIVTCTNSATSIFAGFVIFSVIGFMANERKVNIENVADQGP 543
Query: 388 GLIFIIYPEAIATLPLSSAWAVVFFIMLLTLGIDSAMGGMESVITGLIDEF-QLLHRHRE 446
G+ F++YPEA+ LPLS WA++FF+MLLTLG+D+ +E+++T + DEF + L H+
Sbjct: 544 GIAFVVYPEALTRLPLSPFWAIIFFLMLLTLGLDTMFATIETIVTSISDEFPKYLRTHKP 603
Query: 447 LFTLFIVLATFLLSLFCVTNGGIYVFTLLDHFAAGTSILFGVLIEAIGVAWFYGVGQFSD 506
+FTL + F++ +T GGIY+F L+D +AA +++ + E +G+++ YG+ +F +
Sbjct: 604 VFTLGCCICFFIMGFPMITQGGIYMFQLVDTYAASYALVIIAIFELVGISYVYGLQRFCE 663
Query: 507 DIQQMTGQRPSLYWRLCWKLVSPCFLLFVVVVSIVTFRPPHYGAYIFPDWANALGWVIAT 566
DI+ M G +P+++W++CW V+P L F++ S + P YG+Y +P+W+ LGW++
Sbjct: 664 DIEMMIGFQPNIFWKVCWAFVTPTILTFILCFSFYQWEPMTYGSYRYPNWSMVLGWLMLA 723
Query: 567 SSMAMVPIYAAYKFCSLPGSFREKLAYAIAPEKD 600
S+ +PI K PG F E+L +P+ D
Sbjct: 724 CSVIWIPIMFVIKMHLAPGRFIERLKLVCSPQPD 757
>gi|171184408 solute carrier family 6 (neurotransmitter transporter,
betaine/GABA), member 12 [Homo sapiens]
Length = 614
Score = 515 bits (1327), Expect = e-146
Identities = 249/549 (45%), Positives = 354/549 (64%), Gaps = 10/549 (1%)
Query: 56 EAQDRETWGKKIDFLLSVIGFAVDLANVWRFPYLCYKNGGGAFLVPYLLFMVIAGMPLFY 115
+ +DR W K++F+LSV G + L NVWRFPYLCYKNGGGAF +PY +F + G+P+F+
Sbjct: 32 QVKDRGQWTNKMEFVLSVAGEIIGLGNVWRFPYLCYKNGGGAFFIPYFIFFFVCGIPVFF 91
Query: 116 MELALGQFNREGAAGVW-KICPILKGVGFTVILISLYVGFFYNVIIAWALHYLFSSFTTE 174
+E+ALGQ+ +G+ W KICP+ +G+G ++I Y+ +Y +I+AWAL YLFSSFT+E
Sbjct: 92 LEVALGQYTSQGSVTAWRKICPLFQGIGLASVVIESYLNVYYIIILAWALFYLFSSFTSE 151
Query: 175 LPWIHCNNSWNSPNCSDAHPGDSSGDSSGLNDTFGTTPAAEYFERGVLHLHQSHGIDDLG 234
LPW CNN WN+ +C+D +G + + T+P E++ER VL + + GI DLG
Sbjct: 152 LPWTTCNNFWNTEHCTDFLNHSGAGTVTPFENF--TSPVMEFWERRVLGI--TSGIHDLG 207
Query: 235 PPRWQLTACLVLVIVLLYFSLWKGVKTSGKVVWITATMPYVVLTALLLRGVTLPGAIDGI 294
RW+L CL+L V+ YF +WKGVK++GKVV+ TAT PY++L LL+RGVTLPGA GI
Sbjct: 208 SLRWELALCLLLAWVICYFCIWKGVKSTGKVVYFTATFPYLMLVILLIRGVTLPGAYQGI 267
Query: 295 RAYLSVDFYRLCEASVWIDAATQVCFSLGVGFGVLIAFSSYNKFTNNCYRDAIVTTSINS 354
YL D +RL + VW+DA TQ+ FS + G L A SYNK+ NNCY+D I +NS
Sbjct: 268 IYYLKPDLFRLKDPQVWMDAGTQIFFSFAICQGCLTALGSYNKYHNNCYKDCIALCFLNS 327
Query: 355 LTSFSSGFVVFSFLGYMAQKHSVPIGDVAKDGPGLIFIIYPEAIATLPLSSAWAVVFFIM 414
TSF +GFVVFS LG+M+Q+ VPI +VA+ GPGL FI +P+A+ +PLS W+ +FFIM
Sbjct: 328 ATSFVAGFVVFSILGFMSQEQGVPISEVAESGPGLAFIAFPKAVTMMPLSQLWSCLFFIM 387
Query: 415 LLTLGIDSAMGGMESVITGLIDEFQLLHR---HRELFTLFIVLATFLLSLFCVTNGGIYV 471
L+ LG+DS +E ++T ID F R REL L I + +L+ LF VT GG+Y+
Sbjct: 388 LIFLGLDSQFVCVECLVTASIDMFPRQLRKSGRRELLILTIAVMCYLIGLFLVTEGGMYI 447
Query: 472 FTLLDHFA-AGTSILFGVLIEAIGVAWFYGVGQFSDDIQQMTGQRPSLYWRLCWKLVSPC 530
F L D++A +G +LF L E + ++W YG +F D+I+ M G RP ++ W ++P
Sbjct: 448 FQLFDYYASSGICLLFLSLFEVVCISWVYGADRFYDNIEDMIGYRPWPLVKISWLFLTPG 507
Query: 531 FLLFVVVVSIVTFRPPHY-GAYIFPDWANALGWVIATSSMAMVPIYAAYKFCSLPGSFRE 589
L + S+ + P Y Y++P W ++GW +A SSM VP++ G FR+
Sbjct: 508 LCLATFLFSLSKYTPLKYNNVYVYPPWGYSIGWFLALSSMVCVPLFVVITLLKTRGPFRK 567
Query: 590 KLAYAIAPE 598
+L I P+
Sbjct: 568 RLRQLITPD 576
>gi|171184406 solute carrier family 6 (neurotransmitter transporter,
betaine/GABA), member 12 [Homo sapiens]
Length = 614
Score = 515 bits (1327), Expect = e-146
Identities = 249/549 (45%), Positives = 354/549 (64%), Gaps = 10/549 (1%)
Query: 56 EAQDRETWGKKIDFLLSVIGFAVDLANVWRFPYLCYKNGGGAFLVPYLLFMVIAGMPLFY 115
+ +DR W K++F+LSV G + L NVWRFPYLCYKNGGGAF +PY +F + G+P+F+
Sbjct: 32 QVKDRGQWTNKMEFVLSVAGEIIGLGNVWRFPYLCYKNGGGAFFIPYFIFFFVCGIPVFF 91
Query: 116 MELALGQFNREGAAGVW-KICPILKGVGFTVILISLYVGFFYNVIIAWALHYLFSSFTTE 174
+E+ALGQ+ +G+ W KICP+ +G+G ++I Y+ +Y +I+AWAL YLFSSFT+E
Sbjct: 92 LEVALGQYTSQGSVTAWRKICPLFQGIGLASVVIESYLNVYYIIILAWALFYLFSSFTSE 151
Query: 175 LPWIHCNNSWNSPNCSDAHPGDSSGDSSGLNDTFGTTPAAEYFERGVLHLHQSHGIDDLG 234
LPW CNN WN+ +C+D +G + + T+P E++ER VL + + GI DLG
Sbjct: 152 LPWTTCNNFWNTEHCTDFLNHSGAGTVTPFENF--TSPVMEFWERRVLGI--TSGIHDLG 207
Query: 235 PPRWQLTACLVLVIVLLYFSLWKGVKTSGKVVWITATMPYVVLTALLLRGVTLPGAIDGI 294
RW+L CL+L V+ YF +WKGVK++GKVV+ TAT PY++L LL+RGVTLPGA GI
Sbjct: 208 SLRWELALCLLLAWVICYFCIWKGVKSTGKVVYFTATFPYLMLVILLIRGVTLPGAYQGI 267
Query: 295 RAYLSVDFYRLCEASVWIDAATQVCFSLGVGFGVLIAFSSYNKFTNNCYRDAIVTTSINS 354
YL D +RL + VW+DA TQ+ FS + G L A SYNK+ NNCY+D I +NS
Sbjct: 268 IYYLKPDLFRLKDPQVWMDAGTQIFFSFAICQGCLTALGSYNKYHNNCYKDCIALCFLNS 327
Query: 355 LTSFSSGFVVFSFLGYMAQKHSVPIGDVAKDGPGLIFIIYPEAIATLPLSSAWAVVFFIM 414
TSF +GFVVFS LG+M+Q+ VPI +VA+ GPGL FI +P+A+ +PLS W+ +FFIM
Sbjct: 328 ATSFVAGFVVFSILGFMSQEQGVPISEVAESGPGLAFIAFPKAVTMMPLSQLWSCLFFIM 387
Query: 415 LLTLGIDSAMGGMESVITGLIDEFQLLHR---HRELFTLFIVLATFLLSLFCVTNGGIYV 471
L+ LG+DS +E ++T ID F R REL L I + +L+ LF VT GG+Y+
Sbjct: 388 LIFLGLDSQFVCVECLVTASIDMFPRQLRKSGRRELLILTIAVMCYLIGLFLVTEGGMYI 447
Query: 472 FTLLDHFA-AGTSILFGVLIEAIGVAWFYGVGQFSDDIQQMTGQRPSLYWRLCWKLVSPC 530
F L D++A +G +LF L E + ++W YG +F D+I+ M G RP ++ W ++P
Sbjct: 448 FQLFDYYASSGICLLFLSLFEVVCISWVYGADRFYDNIEDMIGYRPWPLVKISWLFLTPG 507
Query: 531 FLLFVVVVSIVTFRPPHY-GAYIFPDWANALGWVIATSSMAMVPIYAAYKFCSLPGSFRE 589
L + S+ + P Y Y++P W ++GW +A SSM VP++ G FR+
Sbjct: 508 LCLATFLFSLSKYTPLKYNNVYVYPPWGYSIGWFLALSSMVCVPLFVVITLLKTRGPFRK 567
Query: 590 KLAYAIAPE 598
+L I P+
Sbjct: 568 RLRQLITPD 576
>gi|171184404 solute carrier family 6 (neurotransmitter transporter,
betaine/GABA), member 12 [Homo sapiens]
Length = 614
Score = 515 bits (1327), Expect = e-146
Identities = 249/549 (45%), Positives = 354/549 (64%), Gaps = 10/549 (1%)
Query: 56 EAQDRETWGKKIDFLLSVIGFAVDLANVWRFPYLCYKNGGGAFLVPYLLFMVIAGMPLFY 115
+ +DR W K++F+LSV G + L NVWRFPYLCYKNGGGAF +PY +F + G+P+F+
Sbjct: 32 QVKDRGQWTNKMEFVLSVAGEIIGLGNVWRFPYLCYKNGGGAFFIPYFIFFFVCGIPVFF 91
Query: 116 MELALGQFNREGAAGVW-KICPILKGVGFTVILISLYVGFFYNVIIAWALHYLFSSFTTE 174
+E+ALGQ+ +G+ W KICP+ +G+G ++I Y+ +Y +I+AWAL YLFSSFT+E
Sbjct: 92 LEVALGQYTSQGSVTAWRKICPLFQGIGLASVVIESYLNVYYIIILAWALFYLFSSFTSE 151
Query: 175 LPWIHCNNSWNSPNCSDAHPGDSSGDSSGLNDTFGTTPAAEYFERGVLHLHQSHGIDDLG 234
LPW CNN WN+ +C+D +G + + T+P E++ER VL + + GI DLG
Sbjct: 152 LPWTTCNNFWNTEHCTDFLNHSGAGTVTPFENF--TSPVMEFWERRVLGI--TSGIHDLG 207
Query: 235 PPRWQLTACLVLVIVLLYFSLWKGVKTSGKVVWITATMPYVVLTALLLRGVTLPGAIDGI 294
RW+L CL+L V+ YF +WKGVK++GKVV+ TAT PY++L LL+RGVTLPGA GI
Sbjct: 208 SLRWELALCLLLAWVICYFCIWKGVKSTGKVVYFTATFPYLMLVILLIRGVTLPGAYQGI 267
Query: 295 RAYLSVDFYRLCEASVWIDAATQVCFSLGVGFGVLIAFSSYNKFTNNCYRDAIVTTSINS 354
YL D +RL + VW+DA TQ+ FS + G L A SYNK+ NNCY+D I +NS
Sbjct: 268 IYYLKPDLFRLKDPQVWMDAGTQIFFSFAICQGCLTALGSYNKYHNNCYKDCIALCFLNS 327
Query: 355 LTSFSSGFVVFSFLGYMAQKHSVPIGDVAKDGPGLIFIIYPEAIATLPLSSAWAVVFFIM 414
TSF +GFVVFS LG+M+Q+ VPI +VA+ GPGL FI +P+A+ +PLS W+ +FFIM
Sbjct: 328 ATSFVAGFVVFSILGFMSQEQGVPISEVAESGPGLAFIAFPKAVTMMPLSQLWSCLFFIM 387
Query: 415 LLTLGIDSAMGGMESVITGLIDEFQLLHR---HRELFTLFIVLATFLLSLFCVTNGGIYV 471
L+ LG+DS +E ++T ID F R REL L I + +L+ LF VT GG+Y+
Sbjct: 388 LIFLGLDSQFVCVECLVTASIDMFPRQLRKSGRRELLILTIAVMCYLIGLFLVTEGGMYI 447
Query: 472 FTLLDHFA-AGTSILFGVLIEAIGVAWFYGVGQFSDDIQQMTGQRPSLYWRLCWKLVSPC 530
F L D++A +G +LF L E + ++W YG +F D+I+ M G RP ++ W ++P
Sbjct: 448 FQLFDYYASSGICLLFLSLFEVVCISWVYGADRFYDNIEDMIGYRPWPLVKISWLFLTPG 507
Query: 531 FLLFVVVVSIVTFRPPHY-GAYIFPDWANALGWVIATSSMAMVPIYAAYKFCSLPGSFRE 589
L + S+ + P Y Y++P W ++GW +A SSM VP++ G FR+
Sbjct: 508 LCLATFLFSLSKYTPLKYNNVYVYPPWGYSIGWFLALSSMVCVPLFVVITLLKTRGPFRK 567
Query: 590 KLAYAIAPE 598
+L I P+
Sbjct: 568 RLRQLITPD 576
>gi|134304856 solute carrier family 6, member 7 [Homo sapiens]
Length = 636
Score = 509 bits (1312), Expect = e-144
Identities = 253/545 (46%), Positives = 344/545 (63%), Gaps = 1/545 (0%)
Query: 57 AQDRETWGKKIDFLLSVIGFAVDLANVWRFPYLCYKNGGGAFLVPYLLFMVIAGMPLFYM 116
A R W K+DFLLS IG+ V L NVWRFPY Y NGGGAFLVPY L + I G+PLF++
Sbjct: 34 AAHRGNWTGKLDFLLSCIGYCVGLGNVWRFPYRAYTNGGGAFLVPYFLMLAICGIPLFFL 93
Query: 117 ELALGQFNREGAAGVWKICPILKGVGFTVILISLYVGFFYNVIIAWALHYLFSSFTTELP 176
EL+LGQF+ G VWKI P+ KG G ++LI V +YN+IIA+ L YLF+S T++LP
Sbjct: 94 ELSLGQFSSLGPLAVWKISPLFKGAGAAMLLIVGLVAIYYNMIIAYVLFYLFASLTSDLP 153
Query: 177 WIHCNNSWNSPNCSDAHPGDSSGDSSGLNDTFGTTPAAEYFERGVLHLHQSHGIDDLGPP 236
W HC N WN+ C + + LN T +P+ EY+ R VLH+ S GI G
Sbjct: 154 WEHCGNWWNTELCLEHRVSKDGNGALPLNLTCTVSPSEEYWSRYVLHIQGSQGIGSPGEI 213
Query: 237 RWQLTACLVLVIVLLYFSLWKGVKTSGKVVWITATMPYVVLTALLLRGVTLPGAIDGIRA 296
RW L CL+L V+++ + KGVK+SGKVV+ TAT PY++L LL+RGVTLPGA GI+
Sbjct: 214 RWNLCLCLLLAWVIVFLCILKGVKSSGKVVYFTATFPYLILLMLLVRGVTLPGAWKGIQF 273
Query: 297 YLSVDFYRLCEASVWIDAATQVCFSLGVGFGVLIAFSSYNKFTNNCYRDAIVTTSINSLT 356
YL+ F+ L + VWI+AA Q+ +SLGVGFG L+ F+SYN F N YRD + T N++T
Sbjct: 274 YLTPQFHHLLSSKVWIEAALQIFYSLGVGFGGLLTFASYNTFHQNIYRDTFIVTLGNAIT 333
Query: 357 SFSSGFVVFSFLGYMAQKHSVPIGDVAKDGPGLIFIIYPEAIATLPLSSAWAVVFFIMLL 416
S +GF +FS LGYM+Q+ VP+ VAK GPGL F++YP+A+ LPLS W+ +FF MLL
Sbjct: 334 SILAGFAIFSVLGYMSQELGVPVDQVAKAGPGLAFVVYPQAMTMLPLSPFWSFLFFFMLL 393
Query: 417 TLGIDSAMGGMESVITGLIDEF-QLLHRHRELFTLFIVLATFLLSLFCVTNGGIYVFTLL 475
TLG+DS +E+++T + DEF L + +F+ I +A +L+ L T+GG+Y LL
Sbjct: 394 TLGLDSQFAFLETIVTAVTDEFPYYLRPKKAVFSGLICVAMYLMGLILTTDGGMYWLVLL 453
Query: 476 DHFAAGTSILFGVLIEAIGVAWFYGVGQFSDDIQQMTGQRPSLYWRLCWKLVSPCFLLFV 535
D ++A ++ V+ + V YG+ +F DI M G +P LY+R CW +SP LL +
Sbjct: 454 DDYSASFGLMVVVITTCLAVTRVYGIQRFCRDIHMMLGFKPGLYFRACWLFLSPATLLAL 513
Query: 536 VVVSIVTFRPPHYGAYIFPDWANALGWVIATSSMAMVPIYAAYKFCSLPGSFREKLAYAI 595
+V SIV ++P YG+Y FP WA LG ++ S M+P GS E+L A
Sbjct: 514 MVYSIVKYQPSEYGSYRFPPWAELLGILMGLLSCLMIPAGMLVAVLREEGSLWERLQQAS 573
Query: 596 APEKD 600
P D
Sbjct: 574 RPAMD 578
>gi|21361581 solute carrier family 6 (neurotransmitter transporter,
GABA), member 13 [Homo sapiens]
Length = 602
Score = 507 bits (1306), Expect = e-143
Identities = 246/548 (44%), Positives = 352/548 (64%), Gaps = 11/548 (2%)
Query: 59 DRETWGKKIDFLLSVIGFAVDLANVWRFPYLCYKNGGGAFLVPYLLFMVIAGMPLFYMEL 118
+R W K++F+LSV G + L NVWRFPYLCYKNGGGAF +PYL+F+ G+P+F +E
Sbjct: 31 ERGHWNNKMEFVLSVAGEIIGLGNVWRFPYLCYKNGGGAFFIPYLVFLFTCGIPVFLLET 90
Query: 119 ALGQFNREGAAGVW-KICPILKGVGFTVILISLYVGFFYNVIIAWALHYLFSSFTTELPW 177
ALGQ+ +G W KICPI +G+G+ +I + + +Y +++AWAL YLFSSFT +LPW
Sbjct: 91 ALGQYTSQGGVTAWRKICPIFEGIGYASQMIVILLNVYYIIVLAWALFYLFSSFTIDLPW 150
Query: 178 IHCNNSWNSPNCSDAHPGDSSGDSSGLNDTFGTTPAAEYFERGVLHLHQSHGIDDLGPPR 237
C + WN+ +C + + S + + N T+P E++ER VL + S GI LG R
Sbjct: 151 GGCYHEWNTEHCMEFQKTNGSLNGTSEN---ATSPVIEFWERRVLKI--SDGIQHLGALR 205
Query: 238 WQLTACLVLVIVLLYFSLWKGVKTSGKVVWITATMPYVVLTALLLRGVTLPGAIDGIRAY 297
W+L CL+L V+ YF +WKGVK++GKVV+ TAT PY++L LL+RGVTLPGA GI+ Y
Sbjct: 206 WELALCLLLAWVICYFCIWKGVKSTGKVVYFTATFPYLMLVVLLIRGVTLPGAAQGIQFY 265
Query: 298 LSVDFYRLCEASVWIDAATQVCFSLGVGFGVLIAFSSYNKFTNNCYRDAIVTTSINSLTS 357
L + RL + VW+DA TQ+ FS + G L A SYNK+ NNCYRD I +NS TS
Sbjct: 266 LYPNLTRLWDPQVWMDAGTQIFFSFAICLGCLTALGSYNKYHNNCYRDCIALCFLNSGTS 325
Query: 358 FSSGFVVFSFLGYMAQKHSVPIGDVAKDGPGLIFIIYPEAIATLPLSSAWAVVFFIMLLT 417
F +GF +FS LG+M+Q+ VPI +VA+ GPGL FI YP A+ LP S WA FF M++
Sbjct: 326 FVAGFAIFSILGFMSQEQGVPISEVAESGPGLAFIAYPRAVVMLPFSPLWACCFFFMVVL 385
Query: 418 LGIDSAMGGMESVITGLIDEFQLLHR---HRELFTLFIVLATFLLSLFCVTNGGIYVFTL 474
LG+DS +ES++T L+D + + R RE+ L + + +FL+ L +T GG+YVF L
Sbjct: 386 LGLDSQFVCVESLVTALVDMYPHVFRKKNRREVLILGVSVVSFLVGLIMLTEGGMYVFQL 445
Query: 475 LDHFAA-GTSILFGVLIEAIGVAWFYGVGQFSDDIQQMTGQRPSLYWRLCWKLVSPCFLL 533
D++AA G +LF + E++ VAW YG +F D+I+ M G RP + CW ++P
Sbjct: 446 FDYYAASGMCLLFVAIFESLCVAWVYGAKRFYDNIEDMIGYRPWPLIKYCWLFLTPAVCT 505
Query: 534 FVVVVSIVTFRPPHYG-AYIFPDWANALGWVIATSSMAMVPIYAAYKFCSLPGSFREKLA 592
+ S++ + P Y Y +P W +ALGW++A SSM +P ++ Y+ +L G FRE++
Sbjct: 506 ATFLFSLIKYTPLTYNKKYTYPWWGDALGWLLALSSMVCIPAWSLYRLGTLKGPFRERIR 565
Query: 593 YAIAPEKD 600
+ P +D
Sbjct: 566 QLMCPAED 573
>gi|5032097 solute carrier family 6 member 8 isoform 1 [Homo
sapiens]
Length = 635
Score = 506 bits (1302), Expect = e-143
Identities = 244/548 (44%), Positives = 346/548 (63%), Gaps = 12/548 (2%)
Query: 60 RETWGKKIDFLLSVIGFAVDLANVWRFPYLCYKNGGGAFLVPYLLFMVIAGMPLFYMELA 119
RETW +++DF++S +GFAV L NVWRFPYLCYKNGGG FL+PY+L ++ G+P+F++E++
Sbjct: 52 RETWTRQMDFIMSCVGFAVGLGNVWRFPYLCYKNGGGVFLIPYVLIALVGGIPIFFLEIS 111
Query: 120 LGQFNREGAAGVWKICPILKGVGFTVILISLYVGFFYNVIIAWALHYLFSSFTTELPWIH 179
LGQF + G+ VW ICP+ KG+G+ ++I Y +Y +++AW +YL SFTT LPW
Sbjct: 112 LGQFMKAGSINVWNICPLFKGLGYASMVIVFYCNTYYIMVLAWGFYYLVKSFTTTLPWAT 171
Query: 180 CNNSWNSPNCSDAHPGDSSGDSSGLNDTFGT-----TPAAEYFERGVLHLHQSHGIDDLG 234
C ++WN+P+C + + ++S N T +P E++E VL L S G++ G
Sbjct: 172 CGHTWNTPDCVEIFRHEDCANASLANLTCDQLADRRSPVIEFWENKVLRL--SGGLEVPG 229
Query: 235 PPRWQLTACLVLVIVLLYFSLWKGVKTSGKVVWITATMPYVVLTALLLRGVTLPGAIDGI 294
W++T CL+ VL+YF +WKGVK++GK+V+ TAT PYVVL LL+RGV LPGA+DGI
Sbjct: 230 ALNWEVTLCLLACWVLVYFCVWKGVKSTGKIVYFTATFPYVVLVVLLVRGVLLPGALDGI 289
Query: 295 RAYLSVDFYRLCEASVWIDAATQVCFSLGVGFGVLIAFSSYNKFTNNCYRDAIVTTSINS 354
YL D+ +L VWIDA TQ+ FS +G G L A SYN+F NNCY+DAI+ INS
Sbjct: 290 IYYLKPDWSKLGSPQVWIDAGTQIFFSYAIGLGALTALGSYNRFNNNCYKDAIILALINS 349
Query: 355 LTSFSSGFVVFSFLGYMAQKHSVPIGDVAKDGPGLIFIIYPEAIATLPLSSAWAVVFFIM 414
TSF +GFVVFS LG+MA + V I VA+ GPGL FI YP A+ +P++ WA +FF M
Sbjct: 350 GTSFFAGFVVFSILGFMAAEQGVHISKVAESGPGLAFIAYPRAVTLMPVAPLWAALFFFM 409
Query: 415 LLTLGIDSAMGGMESVITGLIDEFQLLHR---HRELFTLFIVLATFLLSLFCVTNGGIYV 471
LL LG+DS G+E ITGL+D + RE+ F++ L VT+GG+YV
Sbjct: 410 LLLLGLDSQFVGVEGFITGLLDLLPASYYFRFQREISVALCCALCFVIDLSMVTDGGMYV 469
Query: 472 FTLLDHF-AAGTSILFGVLIEAIGVAWFYGVGQFSDDIQQMTGQRPSLYWRLCWKLVSPC 530
F L D++ A+GT++L+ E + VAW YG +F DDI M G RP + + CW +P
Sbjct: 470 FQLFDYYSASGTTLLWQAFWECVVVAWVYGADRFMDDIACMIGYRPCPWMKWCWSFFTPL 529
Query: 531 FLLFVVVVSIVTFRPPHY-GAYIFPDWANALGWVIATSSMAMVPIYAAYKFCSLPGSFRE 589
+ + + ++V + P Y Y++P W A+GW A SSM VP++ G+ E
Sbjct: 530 VCMGIFIFNVVYYEPLVYNNTYVYPWWGEAMGWAFALSSMLCVPLHLLGCLLRAKGTMAE 589
Query: 590 KLAYAIAP 597
+ + P
Sbjct: 590 RWQHLTQP 597
>gi|197276623 solute carrier family 6 (neurotransmitter transporter,
taurine), member 6 isoform a [Homo sapiens]
Length = 620
Score = 501 bits (1290), Expect = e-142
Identities = 248/554 (44%), Positives = 349/554 (62%), Gaps = 9/554 (1%)
Query: 60 RETWGKKIDFLLSVIGFAVDLANVWRFPYLCYKNGGGAFLVPYLLFMVIAGMPLFYMELA 119
RE W KIDF+LSV G V L NVWRFPYLCYKNGGGAFL+PY +F+ +G+P+F++E+
Sbjct: 41 REKWSSKIDFVLSVAGGFVGLGNVWRFPYLCYKNGGGAFLIPYFIFLFGSGLPVFFLEII 100
Query: 120 LGQFNREGAAGVW-KICPILKGVGFTVILISLYVGFFYNVIIAWALHYLFSSFTTELPWI 178
+GQ+ EG W KICP+ G+G+ ++I + +Y VI+AWA +YLF SF ELPW
Sbjct: 101 IGQYTSEGGITCWEKICPLFSGIGYASVVIVSLLNVYYIVILAWATYYLFQSFQKELPWA 160
Query: 179 HCNNSWNSPNCSDAHPGDSSGDSSGLNDTFGTTPAAEYFERGVLHLHQSHGIDDLGPPRW 238
HCN+SWN+P+C + + ++ T T+P E++ER VL L S GID G +W
Sbjct: 161 HCNHSWNTPHCMEDTMRKNKSVWITISSTNFTSPVIEFWERNVLSL--SPGIDHPGSLKW 218
Query: 239 QLTACLVLVIVLLYFSLWKGVKTSGKVVWITATMPYVVLTALLLRGVTLPGAIDGIRAYL 298
L CL+LV ++ +F +WKGV+++GKVV+ TAT P+ +L LL+RG+TLPGA GI+ YL
Sbjct: 219 DLALCLLLVWLVCFFCIWKGVRSTGKVVYFTATFPFAMLLVLLVRGLTLPGAGAGIKFYL 278
Query: 299 SVDFYRLCEASVWIDAATQVCFSLGVGFGVLIAFSSYNKFTNNCYRDAIVTTSINSLTSF 358
D RL + VWIDA TQ+ FS + G + + SYNK+ N YRD ++ +NS TSF
Sbjct: 279 YPDITRLEDPQVWIDAGTQIFFSYAICLGAMTSLGSYNKYKYNSYRDCMLLGCLNSGTSF 338
Query: 359 SSGFVVFSFLGYMAQKHSVPIGDVAKDGPGLIFIIYPEAIATLPLSSAWAVVFFIMLLTL 418
SGF +FS LG+MAQ+ V I DVA+ GPGL FI YP+A+ +PL + W+++FFIMLL L
Sbjct: 339 VSGFAIFSILGFMAQEQGVDIADVAESGPGLAFIAYPKAVTMMPLPTFWSILFFIMLLLL 398
Query: 419 GIDSAMGGMESVITGLIDEFQLLHR---HRELFTLFIVLATFLLSLFCVTNGGIYVFTLL 475
G+DS +E IT L+D + R RE+F F+ ++LL L VT GG+YVF L
Sbjct: 399 GLDSQFVEVEGQITSLVDLYPSFLRKGYRREIFIAFVCSISYLLGLTMVTEGGMYVFQLF 458
Query: 476 DHFAA-GTSILFGVLIEAIGVAWFYGVGQFSDDIQQMTGQRPSLYWRLCWKLVSPCFLLF 534
D++AA G +L+ E +AW YG D I+ M G RP + + W +++P +
Sbjct: 459 DYYAASGVCLLWVAFFECFVIAWIYGGDNLYDGIEDMIGYRPGPWMKYSWAVITPVLCVG 518
Query: 535 VVVVSIVTFRPPHYG-AYIFPDWANALGWVIATSSMAMVPIYAAYKFCSLPGSFREKLAY 593
+ S+V + P Y Y++P+WA LGW +A SSM VP+ + C G F ++ Y
Sbjct: 519 CFIFSLVKYVPLTYNKTYVYPNWAIGLGWSLALSSMLCVPLVIVIRLCQTEGPFLVRVKY 578
Query: 594 AIAP-EKDRELVDR 606
+ P E +R V+R
Sbjct: 579 LLTPREPNRWAVER 592
>gi|54607094 solute carrier family 6 (neurotransmitter transporter,
taurine), member 6 isoform a [Homo sapiens]
Length = 620
Score = 501 bits (1290), Expect = e-142
Identities = 248/554 (44%), Positives = 349/554 (62%), Gaps = 9/554 (1%)
Query: 60 RETWGKKIDFLLSVIGFAVDLANVWRFPYLCYKNGGGAFLVPYLLFMVIAGMPLFYMELA 119
RE W KIDF+LSV G V L NVWRFPYLCYKNGGGAFL+PY +F+ +G+P+F++E+
Sbjct: 41 REKWSSKIDFVLSVAGGFVGLGNVWRFPYLCYKNGGGAFLIPYFIFLFGSGLPVFFLEII 100
Query: 120 LGQFNREGAAGVW-KICPILKGVGFTVILISLYVGFFYNVIIAWALHYLFSSFTTELPWI 178
+GQ+ EG W KICP+ G+G+ ++I + +Y VI+AWA +YLF SF ELPW
Sbjct: 101 IGQYTSEGGITCWEKICPLFSGIGYASVVIVSLLNVYYIVILAWATYYLFQSFQKELPWA 160
Query: 179 HCNNSWNSPNCSDAHPGDSSGDSSGLNDTFGTTPAAEYFERGVLHLHQSHGIDDLGPPRW 238
HCN+SWN+P+C + + ++ T T+P E++ER VL L S GID G +W
Sbjct: 161 HCNHSWNTPHCMEDTMRKNKSVWITISSTNFTSPVIEFWERNVLSL--SPGIDHPGSLKW 218
Query: 239 QLTACLVLVIVLLYFSLWKGVKTSGKVVWITATMPYVVLTALLLRGVTLPGAIDGIRAYL 298
L CL+LV ++ +F +WKGV+++GKVV+ TAT P+ +L LL+RG+TLPGA GI+ YL
Sbjct: 219 DLALCLLLVWLVCFFCIWKGVRSTGKVVYFTATFPFAMLLVLLVRGLTLPGAGAGIKFYL 278
Query: 299 SVDFYRLCEASVWIDAATQVCFSLGVGFGVLIAFSSYNKFTNNCYRDAIVTTSINSLTSF 358
D RL + VWIDA TQ+ FS + G + + SYNK+ N YRD ++ +NS TSF
Sbjct: 279 YPDITRLEDPQVWIDAGTQIFFSYAICLGAMTSLGSYNKYKYNSYRDCMLLGCLNSGTSF 338
Query: 359 SSGFVVFSFLGYMAQKHSVPIGDVAKDGPGLIFIIYPEAIATLPLSSAWAVVFFIMLLTL 418
SGF +FS LG+MAQ+ V I DVA+ GPGL FI YP+A+ +PL + W+++FFIMLL L
Sbjct: 339 VSGFAIFSILGFMAQEQGVDIADVAESGPGLAFIAYPKAVTMMPLPTFWSILFFIMLLLL 398
Query: 419 GIDSAMGGMESVITGLIDEFQLLHR---HRELFTLFIVLATFLLSLFCVTNGGIYVFTLL 475
G+DS +E IT L+D + R RE+F F+ ++LL L VT GG+YVF L
Sbjct: 399 GLDSQFVEVEGQITSLVDLYPSFLRKGYRREIFIAFVCSISYLLGLTMVTEGGMYVFQLF 458
Query: 476 DHFAA-GTSILFGVLIEAIGVAWFYGVGQFSDDIQQMTGQRPSLYWRLCWKLVSPCFLLF 534
D++AA G +L+ E +AW YG D I+ M G RP + + W +++P +
Sbjct: 459 DYYAASGVCLLWVAFFECFVIAWIYGGDNLYDGIEDMIGYRPGPWMKYSWAVITPVLCVG 518
Query: 535 VVVVSIVTFRPPHYG-AYIFPDWANALGWVIATSSMAMVPIYAAYKFCSLPGSFREKLAY 593
+ S+V + P Y Y++P+WA LGW +A SSM VP+ + C G F ++ Y
Sbjct: 519 CFIFSLVKYVPLTYNKTYVYPNWAIGLGWSLALSSMLCVPLVIVIRLCQTEGPFLVRVKY 578
Query: 594 AIAP-EKDRELVDR 606
+ P E +R V+R
Sbjct: 579 LLTPREPNRWAVER 592
>gi|7657587 solute carrier family 6 (neurotransmitter transporter,
GABA), member 11 [Homo sapiens]
Length = 632
Score = 493 bits (1268), Expect = e-139
Identities = 234/551 (42%), Positives = 347/551 (62%), Gaps = 9/551 (1%)
Query: 59 DRETWGKKIDFLLSVIGFAVDLANVWRFPYLCYKNGGGAFLVPYLLFMVIAGMPLFYMEL 118
+R W K++F+LSV G + L NVWRFPYLCYKNGGGAFL+PY++F + G+P+F++E
Sbjct: 49 ERGHWNNKVEFVLSVAGEIIGLGNVWRFPYLCYKNGGGAFLIPYVVFFICCGIPVFFLET 108
Query: 119 ALGQFNREGAAGVW-KICPILKGVGFTVILISLYVGFFYNVIIAWALHYLFSSFTTELPW 177
ALGQF EG W K+CP+ +G+G+ +I ++ +Y +I+AWA+ YL + FTTELPW
Sbjct: 109 ALGQFTSEGGITCWRKVCPLFEGIGYATQVIEAHLNVYYIIILAWAIFYLSNCFTTELPW 168
Query: 178 IHCNNSWNSPNCSDAHPGDSSGDSSGLNDTFGTTPAAEYFERGVLHLHQSHGIDDLGPPR 237
C + WN+ NC + + S + S ++ T+P E++E VL + S GI+ +G R
Sbjct: 169 ATCGHEWNTENCVEFQKLNVS-NYSHVSLQNATSPVMEFWEHRVLAI--SDGIEHIGNLR 225
Query: 238 WQLTACLVLVIVLLYFSLWKGVKTSGKVVWITATMPYVVLTALLLRGVTLPGAIDGIRAY 297
W+L CL+ + YF +WKG K++GKVV++TAT PY++L LL+RGVTLPGA +GI+ Y
Sbjct: 226 WELALCLLAAWTICYFCIWKGTKSTGKVVYVTATFPYIMLLILLIRGVTLPGASEGIKFY 285
Query: 298 LSVDFYRLCEASVWIDAATQVCFSLGVGFGVLIAFSSYNKFTNNCYRDAIVTTSINSLTS 357
L D RL + VW+DA TQ+ FS + G L A SYN + NNCYRD I+ +NS TS
Sbjct: 286 LYPDLSRLSDPQVWVDAGTQIFFSYAICLGCLTALGSYNNYNNNCYRDCIMLCCLNSGTS 345
Query: 358 FSSGFVVFSFLGYMAQKHSVPIGDVAKDGPGLIFIIYPEAIATLPLSSAWAVVFFIMLLT 417
F +GF +FS LG+MA + VPI +VA+ GPGL FI YP+A+ +PLS WA +FF+ML+
Sbjct: 346 FVAGFAIFSVLGFMAYEQGVPIAEVAESGPGLAFIAYPKAVTMMPLSPLWATLFFMMLIF 405
Query: 418 LGIDSAMGGMESVITGLIDEFQLLHR---HRELFTLFIVLATFLLSLFCVTNGGIYVFTL 474
LG+DS +ES++T ++D + + R REL L + + ++ L L +T GG+Y+F L
Sbjct: 406 LGLDSQFVCVESLVTAVVDMYPKVFRRGYRRELLILALSVISYFLGLVMLTEGGMYIFQL 465
Query: 475 LDHFAA-GTSILFGVLIEAIGVAWFYGVGQFSDDIQQMTGQRPSLYWRLCWKLVSPCFLL 533
D +AA G +LF + E I + W YG +F D+I+ M G RP + CW +++P
Sbjct: 466 FDSYAASGMCLLFVAIFECICIGWVYGSNRFYDNIEDMIGYRPPSLIKWCWMIMTPGICA 525
Query: 534 FVVVVSIVTFRPPHY-GAYIFPDWANALGWVIATSSMAMVPIYAAYKFCSLPGSFREKLA 592
+ + ++ ++P Y Y +P W +GW++A SSM +P++ G+ EKL
Sbjct: 526 GIFIFFLIKYKPLKYNNIYTYPAWGYGIGWLMALSSMLCIPLWICITVWKTEGTLPEKLQ 585
Query: 593 YAIAPEKDREL 603
P D ++
Sbjct: 586 KLTTPSTDLKM 596
>gi|218563756 solute carrier family 6 member 8 isoform 2 [Homo
sapiens]
Length = 625
Score = 487 bits (1254), Expect = e-137
Identities = 238/548 (43%), Positives = 338/548 (61%), Gaps = 22/548 (4%)
Query: 60 RETWGKKIDFLLSVIGFAVDLANVWRFPYLCYKNGGGAFLVPYLLFMVIAGMPLFYMELA 119
RETW +++DF++S +GFAV L NVWRFPYLCYKNGGG FL+PY+L ++ G+P+F++E++
Sbjct: 52 RETWTRQMDFIMSCVGFAVGLGNVWRFPYLCYKNGGGVFLIPYVLIALVGGIPIFFLEIS 111
Query: 120 LGQFNREGAAGVWKICPILKGVGFTVILISLYVGFFYNVIIAWALHYLFSSFTTELPWIH 179
LGQF + G+ VW ICP+ KG+G+ ++I Y +Y +++AW +YL SFTT LPW
Sbjct: 112 LGQFMKAGSINVWNICPLFKGLGYASMVIVFYCNTYYIMVLAWGFYYLVKSFTTTLPWAT 171
Query: 180 CNNSWNSPNCSDAHPGDSSGDSSGLNDTFG-----TTPAAEYFERGVLHLHQSHGIDDLG 234
C ++WN+P+C + + ++S N T +P E++E VL L S G++ G
Sbjct: 172 CGHTWNTPDCVEIFRHEDCANASLANLTCDQLADRRSPVIEFWENKVLRL--SGGLEVPG 229
Query: 235 PPRWQLTACLVLVIVLLYFSLWKGVKTSGKVVWITATMPYVVLTALLLRGVTLPGAIDGI 294
W++T CL+ VL+YF +WKGVK++GK+V+ TAT PYVVL LL+RGV LPGA+DGI
Sbjct: 230 ALNWEVTLCLLACWVLVYFCVWKGVKSTGKIVYFTATFPYVVLVVLLVRGVLLPGALDGI 289
Query: 295 RAYLSVDFYRLCEASVWIDAATQVCFSLGVGFGVLIAFSSYNKFTNNCYRDAIVTTSINS 354
YL D+ +L VWIDA TQ+ FS +G G L A SYN+F NNCY
Sbjct: 290 IYYLKPDWSKLGSPQVWIDAGTQIFFSYAIGLGALTALGSYNRFNNNCYNG--------- 340
Query: 355 LTSFSSGFVVFSFLGYMAQKHSVPIGDVAKDGPGLIFIIYPEAIATLPLSSAWAVVFFIM 414
TSF +GFVVFS LG+MA + V I VA+ GPGL FI YP A+ +P++ WA +FF M
Sbjct: 341 -TSFFAGFVVFSILGFMAAEQGVHISKVAESGPGLAFIAYPRAVTLMPVAPLWAALFFFM 399
Query: 415 LLTLGIDSAMGGMESVITGLIDEFQLLHR---HRELFTLFIVLATFLLSLFCVTNGGIYV 471
LL LG+DS G+E ITGL+D + RE+ F++ L VT+GG+YV
Sbjct: 400 LLLLGLDSQFVGVEGFITGLLDLLPASYYFRFQREISVALCCALCFVIDLSMVTDGGMYV 459
Query: 472 FTLLDHF-AAGTSILFGVLIEAIGVAWFYGVGQFSDDIQQMTGQRPSLYWRLCWKLVSPC 530
F L D++ A+GT++L+ E + VAW YG +F DDI M G RP + + CW +P
Sbjct: 460 FQLFDYYSASGTTLLWQAFWECVVVAWVYGADRFMDDIACMIGYRPCPWMKWCWSFFTPL 519
Query: 531 FLLFVVVVSIVTFRPPHY-GAYIFPDWANALGWVIATSSMAMVPIYAAYKFCSLPGSFRE 589
+ + + ++V + P Y Y++P W A+GW A SSM VP++ G+ E
Sbjct: 520 VCMGIFIFNVVYYEPLVYNNTYVYPWWGEAMGWAFALSSMLCVPLHLLGCLLRAKGTMAE 579
Query: 590 KLAYAIAP 597
+ + P
Sbjct: 580 RWQHLTQP 587
>gi|67782313 solute carrier family 6 member 9 isoform 1 [Homo
sapiens]
Length = 652
Score = 478 bits (1229), Expect = e-135
Identities = 239/582 (41%), Positives = 365/582 (62%), Gaps = 27/582 (4%)
Query: 36 EQNGVQLTSSTLTNPRQSPVEAQDRETWGKKIDFLLSVIGFAVDLANVWRFPYLCYKNGG 95
EQNG + +T + R WG +I+F+L+ +G+AV L NVWRFPYLCY+NGG
Sbjct: 28 EQNGAVPSEATKRDQNLK------RGNWGNQIEFVLTSVGYAVGLGNVWRFPYLCYRNGG 81
Query: 96 GAFLVPYLLFMVIAGMPLFYMELALGQFNREGAAGVWKICPILKGVGFTVILISLYVGFF 155
GAF+ PY + ++ G+PLF+MEL+ GQF +G GVW+I P+ KGVG+ ++++S Y+G +
Sbjct: 82 GAFMFPYFIMLIFCGIPLFFMELSFGQFASQGCLGVWRISPMFKGVGYGMMVVSTYIGIY 141
Query: 156 YNVIIAWALHYLFSSFTTELPWIHCNNSWNSPNCSDAHPGDSSGDSSG------------ 203
YNV+I A +Y FSS T LPW +CNN WN+ +C+ D+S ++G
Sbjct: 142 YNVVICIAFYYFFSSMTHVLPWAYCNNPWNTHDCAGVL--DASNLTNGSRPAALPSNLSH 199
Query: 204 -LNDTFG-TTPAAEYFERGVLHLHQSHGIDDLGPPRWQLTACLVLVIVLLYFSLWKGVKT 261
LN + T+P+ EY+ VL L S I + G R L CL + ++++ L +GVK+
Sbjct: 200 LLNHSLQRTSPSEEYWRLYVLKL--SDDIGNFGEVRLPLLGCLGVSWLVVFLCLIRGVKS 257
Query: 262 SGKVVWITATMPYVVLTALLLRGVTLPGAIDGIRAYLSVDFYRLCEASVWIDAATQVCFS 321
SGKVV+ TAT PYVVLT L +RGVTL GA DGI YL+ + ++ EA VW DAA+Q+ +S
Sbjct: 258 SGKVVYFTATFPYVVLTILFVRGVTLEGAFDGIMYYLTPQWDKILEAKVWGDAASQIFYS 317
Query: 322 LGVGFGVLIAFSSYNKFTNNCYRDAIVTTSINSLTSFSSGFVVFSFLGYMAQKHSVPIGD 381
LG +G LI +SYNKF NNCYRD+++ + N TS +GFV+FS LG+MA V +
Sbjct: 318 LGCAWGGLITMASYNKFHNNCYRDSVIISITNCATSVYAGFVIFSILGFMANHLGVDVSR 377
Query: 382 VAKDGPGLIFIIYPEAIATLPLSSAWAVVFFIMLLTLGIDSAMGGMESVITGLIDEF--Q 439
VA GPGL F+ YPEA+ LP+S W+++FF ML+ LG+ + +E+++T ++DE +
Sbjct: 378 VADHGPGLAFVAYPEALTLLPISPLWSLLFFFMLILLGLGTQFCLLETLVTAIVDEVGNE 437
Query: 440 LLHRHRELFTLFIVLATFLLSLFCVTNGGIYVFTLLDHFAAGTSILFGVLIEAIGVAWFY 499
+ + + TL + +A FLL + + GIY L+D++AA S++ I + + + Y
Sbjct: 438 WILQKKTYVTLGVAVAGFLLGIPLTSQAGIYWLLLMDNYAASFSLVVISCIMCVAIMYIY 497
Query: 500 GVGQFSDDIQQMTGQRPSLYWRLCWKLVSPCFLLFVVVVSIVTFRPPHYGAYIFPDWANA 559
G + DIQ M G P L++++CW+ VSP + F++V +++ ++P Y Y +P WA A
Sbjct: 498 GHRNYFQDIQMMLGFPPPLFFQICWRFVSPAIIFFILVFTVIQYQPITYNHYQYPGWAVA 557
Query: 560 LGWVIATSSMAMVPIYAAYKFCSLPG-SFREKLAYAIAPEKD 600
+G+++A SS+ +P+YA ++ C G + ++L A P +D
Sbjct: 558 IGFLMALSSVLCIPLYAMFRLCRTDGDTLLQRLKNATKPSRD 599
>gi|67782317 solute carrier family 6 member 9 isoform 3 [Homo
sapiens]
Length = 633
Score = 477 bits (1227), Expect = e-134
Identities = 234/558 (41%), Positives = 357/558 (63%), Gaps = 21/558 (3%)
Query: 60 RETWGKKIDFLLSVIGFAVDLANVWRFPYLCYKNGGGAFLVPYLLFMVIAGMPLFYMELA 119
R WG +I+F+L+ +G+AV L NVWRFPYLCY+NGGGAF+ PY + ++ G+PLF+MEL+
Sbjct: 27 RGNWGNQIEFVLTSVGYAVGLGNVWRFPYLCYRNGGGAFMFPYFIMLIFCGIPLFFMELS 86
Query: 120 LGQFNREGAAGVWKICPILKGVGFTVILISLYVGFFYNVIIAWALHYLFSSFTTELPWIH 179
GQF +G GVW+I P+ KGVG+ ++++S Y+G +YNV+I A +Y FSS T LPW +
Sbjct: 87 FGQFASQGCLGVWRISPMFKGVGYGMMVVSTYIGIYYNVVICIAFYYFFSSMTHVLPWAY 146
Query: 180 CNNSWNSPNCSDAHPGDSSGDSSG-------------LNDTFG-TTPAAEYFERGVLHLH 225
CNN WN+ +C+ D+S ++G LN + T+P+ EY+ VL L
Sbjct: 147 CNNPWNTHDCAGVL--DASNLTNGSRPAALPSNLSHLLNHSLQRTSPSEEYWRLYVLKL- 203
Query: 226 QSHGIDDLGPPRWQLTACLVLVIVLLYFSLWKGVKTSGKVVWITATMPYVVLTALLLRGV 285
S I + G R L CL + ++++ L +GVK+SGKVV+ TAT PYVVLT L +RGV
Sbjct: 204 -SDDIGNFGEVRLPLLGCLGVSWLVVFLCLIRGVKSSGKVVYFTATFPYVVLTILFVRGV 262
Query: 286 TLPGAIDGIRAYLSVDFYRLCEASVWIDAATQVCFSLGVGFGVLIAFSSYNKFTNNCYRD 345
TL GA DGI YL+ + ++ EA VW DAA+Q+ +SLG +G LI +SYNKF NNCYRD
Sbjct: 263 TLEGAFDGIMYYLTPQWDKILEAKVWGDAASQIFYSLGCAWGGLITMASYNKFHNNCYRD 322
Query: 346 AIVTTSINSLTSFSSGFVVFSFLGYMAQKHSVPIGDVAKDGPGLIFIIYPEAIATLPLSS 405
+++ + N TS +GFV+FS LG+MA V + VA GPGL F+ YPEA+ LP+S
Sbjct: 323 SVIISITNCATSVYAGFVIFSILGFMANHLGVDVSRVADHGPGLAFVAYPEALTLLPISP 382
Query: 406 AWAVVFFIMLLTLGIDSAMGGMESVITGLIDEF--QLLHRHRELFTLFIVLATFLLSLFC 463
W+++FF ML+ LG+ + +E+++T ++DE + + + + TL + +A FLL +
Sbjct: 383 LWSLLFFFMLILLGLGTQFCLLETLVTAIVDEVGNEWILQKKTYVTLGVAVAGFLLGIPL 442
Query: 464 VTNGGIYVFTLLDHFAAGTSILFGVLIEAIGVAWFYGVGQFSDDIQQMTGQRPSLYWRLC 523
+ GIY L+D++AA S++ I + + + YG + DIQ M G P L++++C
Sbjct: 443 TSQAGIYWLLLMDNYAASFSLVVISCIMCVAIMYIYGHRNYFQDIQMMLGFPPPLFFQIC 502
Query: 524 WKLVSPCFLLFVVVVSIVTFRPPHYGAYIFPDWANALGWVIATSSMAMVPIYAAYKFCSL 583
W+ VSP + F++V +++ ++P Y Y +P WA A+G+++A SS+ +P+YA ++ C
Sbjct: 503 WRFVSPAIIFFILVFTVIQYQPITYNHYQYPGWAVAIGFLMALSSVLCIPLYAMFRLCRT 562
Query: 584 PG-SFREKLAYAIAPEKD 600
G + ++L A P +D
Sbjct: 563 DGDTLLQRLKNATKPSRD 580
>gi|67782315 solute carrier family 6 member 9 isoform 2 [Homo
sapiens]
Length = 706
Score = 477 bits (1227), Expect = e-134
Identities = 234/558 (41%), Positives = 357/558 (63%), Gaps = 21/558 (3%)
Query: 60 RETWGKKIDFLLSVIGFAVDLANVWRFPYLCYKNGGGAFLVPYLLFMVIAGMPLFYMELA 119
R WG +I+F+L+ +G+AV L NVWRFPYLCY+NGGGAF+ PY + ++ G+PLF+MEL+
Sbjct: 100 RGNWGNQIEFVLTSVGYAVGLGNVWRFPYLCYRNGGGAFMFPYFIMLIFCGIPLFFMELS 159
Query: 120 LGQFNREGAAGVWKICPILKGVGFTVILISLYVGFFYNVIIAWALHYLFSSFTTELPWIH 179
GQF +G GVW+I P+ KGVG+ ++++S Y+G +YNV+I A +Y FSS T LPW +
Sbjct: 160 FGQFASQGCLGVWRISPMFKGVGYGMMVVSTYIGIYYNVVICIAFYYFFSSMTHVLPWAY 219
Query: 180 CNNSWNSPNCSDAHPGDSSGDSSG-------------LNDTFG-TTPAAEYFERGVLHLH 225
CNN WN+ +C+ D+S ++G LN + T+P+ EY+ VL L
Sbjct: 220 CNNPWNTHDCAGVL--DASNLTNGSRPAALPSNLSHLLNHSLQRTSPSEEYWRLYVLKL- 276
Query: 226 QSHGIDDLGPPRWQLTACLVLVIVLLYFSLWKGVKTSGKVVWITATMPYVVLTALLLRGV 285
S I + G R L CL + ++++ L +GVK+SGKVV+ TAT PYVVLT L +RGV
Sbjct: 277 -SDDIGNFGEVRLPLLGCLGVSWLVVFLCLIRGVKSSGKVVYFTATFPYVVLTILFVRGV 335
Query: 286 TLPGAIDGIRAYLSVDFYRLCEASVWIDAATQVCFSLGVGFGVLIAFSSYNKFTNNCYRD 345
TL GA DGI YL+ + ++ EA VW DAA+Q+ +SLG +G LI +SYNKF NNCYRD
Sbjct: 336 TLEGAFDGIMYYLTPQWDKILEAKVWGDAASQIFYSLGCAWGGLITMASYNKFHNNCYRD 395
Query: 346 AIVTTSINSLTSFSSGFVVFSFLGYMAQKHSVPIGDVAKDGPGLIFIIYPEAIATLPLSS 405
+++ + N TS +GFV+FS LG+MA V + VA GPGL F+ YPEA+ LP+S
Sbjct: 396 SVIISITNCATSVYAGFVIFSILGFMANHLGVDVSRVADHGPGLAFVAYPEALTLLPISP 455
Query: 406 AWAVVFFIMLLTLGIDSAMGGMESVITGLIDEF--QLLHRHRELFTLFIVLATFLLSLFC 463
W+++FF ML+ LG+ + +E+++T ++DE + + + + TL + +A FLL +
Sbjct: 456 LWSLLFFFMLILLGLGTQFCLLETLVTAIVDEVGNEWILQKKTYVTLGVAVAGFLLGIPL 515
Query: 464 VTNGGIYVFTLLDHFAAGTSILFGVLIEAIGVAWFYGVGQFSDDIQQMTGQRPSLYWRLC 523
+ GIY L+D++AA S++ I + + + YG + DIQ M G P L++++C
Sbjct: 516 TSQAGIYWLLLMDNYAASFSLVVISCIMCVAIMYIYGHRNYFQDIQMMLGFPPPLFFQIC 575
Query: 524 WKLVSPCFLLFVVVVSIVTFRPPHYGAYIFPDWANALGWVIATSSMAMVPIYAAYKFCSL 583
W+ VSP + F++V +++ ++P Y Y +P WA A+G+++A SS+ +P+YA ++ C
Sbjct: 576 WRFVSPAIIFFILVFTVIQYQPITYNHYQYPGWAVAIGFLMALSSVLCIPLYAMFRLCRT 635
Query: 584 PG-SFREKLAYAIAPEKD 600
G + ++L A P +D
Sbjct: 636 DGDTLLQRLKNATKPSRD 653
>gi|6005715 solute carrier family 6 (amino acid transporter), member
14 [Homo sapiens]
Length = 642
Score = 476 bits (1226), Expect = e-134
Identities = 248/574 (43%), Positives = 350/574 (60%), Gaps = 35/574 (6%)
Query: 56 EAQDRETWGKKIDFLLSVIGFAVDLANVWRFPYLCYKNGGGAFLVPYLLFMVIAGMPLFY 115
E QDR W KK D+LLS+IG+AV L NVWRFPYL Y NGGGAFL+PY + + +AG+PLF+
Sbjct: 32 ENQDRGNWSKKSDYLLSMIGYAVGLGNVWRFPYLTYSNGGGAFLIPYAIMLALAGLPLFF 91
Query: 116 MELALGQFNREGAAGVWKICPILKGVGFTVILISLYVGFFYNVIIAWALHYLFSSFTTEL 175
+E +LGQF G VW+I P+ +GVG T++LIS++V +YNVIIA++L+Y+F+SF +EL
Sbjct: 92 LECSLGQFASLGPVSVWRILPLFQGVGITMVLISIFVTIYYNVIIAYSLYYMFASFQSEL 151
Query: 176 PWIHCNNSWNSPNCSDA---HPGDSSGDSSGLNDTF-----------------------G 209
PW +C +SW+ NCS + + S + G+ + G
Sbjct: 152 PWKNC-SSWSDKNCSRSPIVTHCNVSTVNKGIQEIIQMNKSWVDINNFTCINGSEIYQPG 210
Query: 210 TTPAAEYFERGVLHLHQSHGIDDLGPPRWQLTACLVLVIVLLYFSLWKGVKTSGKVVWIT 269
P+ +Y+ + + L +S G+++ G W L CL+L +++ +L+KG+K+SGKVV+ T
Sbjct: 211 QLPSEQYWNK--VALQRSSGMNETGVIVWYLALCLLLAWLIVGAALFKGIKSSGKVVYFT 268
Query: 270 ATMPYVVLTALLLRGVTLPGAIDGIRAYLSV--DFYRLCEASVWIDAATQVCFSLGVGFG 327
A PYVVL LL+RG TL GA GI Y+ +F +L EA VW DAATQ+ +SL V +G
Sbjct: 269 ALFPYVVLLILLVRGATLEGASKGISYYIGAQSNFTKLKEAEVWKDAATQIFYSLSVAWG 328
Query: 328 VLIAFSSYNKFTNNCYRDAIVTTSINSLTSFSSGFVVFSFLGYMAQKHSVPIGDVAKDGP 387
L+A SSYNKF NNC+ DAIV N LTS +GF +FS LG+MA + V K G
Sbjct: 329 GLVALSSYNKFKNNCFSDAIVVCLTNCLTSVFAGFAIFSILGHMAHISGKEVSQVVKSGF 388
Query: 388 GLIFIIYPEAIATLPLSSAWAVVFFIMLLTLGIDSAMGGMESVITGLIDEF-QLLHRHRE 446
L FI YPEA+A LP W+++FF MLLTLG+DS +E++ T + D F +++ + R
Sbjct: 389 DLAFIAYPEALAQLPGGPFWSILFFFMLLTLGLDSQFASIETITTTIQDLFPKVMKKMRV 448
Query: 447 LFTLFIVLATFLLSLFCVTNGGIYVFTLLDHFAAGTSILFGVLIEAIGVAWFYGVGQFSD 506
TL L FLL L CVT GIY L+DHF AG IL ++E +G+ W YG +F +
Sbjct: 449 PITLGCCLVLFLLGLVCVTQAGIYWVHLIDHFCAGWGILIAAILELVGIIWIYGGNRFIE 508
Query: 507 DIQQMTGQRP---SLYWRLCWKLVSPCFLLFVVVVSIVTFRPPHYGAYIFPDWANALGWV 563
D + M G + L+WR CW +++P L+ + + S+V F P+YGA +PDW ALGW
Sbjct: 509 DTEMMIGAKRWIFWLWWRACWFVITPILLIAIFIWSLVQFHRPNYGAIPYPDWGVALGWC 568
Query: 564 IATSSMAMVPIYAAYKFCSLPGSFREKLAYAIAP 597
+ + +PI A K G+ ++L P
Sbjct: 569 MIVFCIIWIPIMAIIKIIQAKGNIFQRLISCCRP 602
>gi|218563758 solute carrier family 6 member 8 isoform 3 [Homo
sapiens]
Length = 520
Score = 407 bits (1045), Expect = e-113
Identities = 204/483 (42%), Positives = 290/483 (60%), Gaps = 12/483 (2%)
Query: 125 REGAAGVWKICPILKGVGFTVILISLYVGFFYNVIIAWALHYLFSSFTTELPWIHCNNSW 184
+ G+ VW ICP+ KG+G+ ++I Y +Y +++AW +YL SFTT LPW C ++W
Sbjct: 2 KAGSINVWNICPLFKGLGYASMVIVFYCNTYYIMVLAWGFYYLVKSFTTTLPWATCGHTW 61
Query: 185 NSPNCSDAHPGDSSGDSSGLNDTFGT-----TPAAEYFERGVLHLHQSHGIDDLGPPRWQ 239
N+P+C + + ++S N T +P E++E VL L S G++ G W+
Sbjct: 62 NTPDCVEIFRHEDCANASLANLTCDQLADRRSPVIEFWENKVLRL--SGGLEVPGALNWE 119
Query: 240 LTACLVLVIVLLYFSLWKGVKTSGKVVWITATMPYVVLTALLLRGVTLPGAIDGIRAYLS 299
+T CL+ VL+YF +WKGVK++GK+V+ TAT PYVVL LL+RGV LPGA+DGI YL
Sbjct: 120 VTLCLLACWVLVYFCVWKGVKSTGKIVYFTATFPYVVLVVLLVRGVLLPGALDGIIYYLK 179
Query: 300 VDFYRLCEASVWIDAATQVCFSLGVGFGVLIAFSSYNKFTNNCYRDAIVTTSINSLTSFS 359
D+ +L VWIDA TQ+ FS +G G L A SYN+F NNCY+DAI+ INS TSF
Sbjct: 180 PDWSKLGSPQVWIDAGTQIFFSYAIGLGALTALGSYNRFNNNCYKDAIILALINSGTSFF 239
Query: 360 SGFVVFSFLGYMAQKHSVPIGDVAKDGPGLIFIIYPEAIATLPLSSAWAVVFFIMLLTLG 419
+GFVVFS LG+MA + V I VA+ GPGL FI YP A+ +P++ WA +FF MLL LG
Sbjct: 240 AGFVVFSILGFMAAEQGVHISKVAESGPGLAFIAYPRAVTLMPVAPLWAALFFFMLLLLG 299
Query: 420 IDSAMGGMESVITGLIDEFQLLHR---HRELFTLFIVLATFLLSLFCVTNGGIYVFTLLD 476
+DS G+E ITGL+D + RE+ F++ L VT+GG+YVF L D
Sbjct: 300 LDSQFVGVEGFITGLLDLLPASYYFRFQREISVALCCALCFVIDLSMVTDGGMYVFQLFD 359
Query: 477 HF-AAGTSILFGVLIEAIGVAWFYGVGQFSDDIQQMTGQRPSLYWRLCWKLVSPCFLLFV 535
++ A+GT++L+ E + VAW YG +F DDI M G RP + + CW +P + +
Sbjct: 360 YYSASGTTLLWQAFWECVVVAWVYGADRFMDDIACMIGYRPCPWMKWCWSFFTPLVCMGI 419
Query: 536 VVVSIVTFRPPHY-GAYIFPDWANALGWVIATSSMAMVPIYAAYKFCSLPGSFREKLAYA 594
+ ++V + P Y Y++P W A+GW A SSM VP++ G+ E+ +
Sbjct: 420 FIFNVVYYEPLVYNNTYVYPWWGEAMGWAFALSSMLCVPLHLLGCLLRAKGTMAERWQHL 479
Query: 595 IAP 597
P
Sbjct: 480 TQP 482
>gi|51468073 solute carrier family 6, member 19 [Homo sapiens]
Length = 634
Score = 360 bits (925), Expect = 2e-99
Identities = 212/603 (35%), Positives = 308/603 (51%), Gaps = 89/603 (14%)
Query: 56 EAQDRETWGKKIDFLLSVIGFAVDLANVWRFPYLCYKNGGGAFLVPYLLFMVIAGMPLFY 115
EA R W K ++L+ +GF V L NVWRFPYLC +GGGAF++P+L+ +V+ G+PL Y
Sbjct: 28 EASSRPKWDNKAQYMLTCLGFCVGLGNVWRFPYLCQSHGGGAFMIPFLILLVLEGIPLLY 87
Query: 116 MELALGQFNREGAAGVWK-ICPILKGVGFTVILISLYVGFFYNVIIAWALHYLFSSFTTE 174
+E A+GQ R G+ GVW I P LKG+G +L S VG +YN II+W + YLF+SF
Sbjct: 88 LEFAIGQRLRRGSLGVWSSIHPALKGLGLASMLTSFMVGLYYNTIISWIMWYLFNSFQEP 147
Query: 175 LPWIHCNNSWNSPNCSDAHPGDSSGDSSGLNDTFGTTPAAEYFERGVLHLHQSHGIDDLG 234
LPW C + N D + ++P ++ R L++ S I D G
Sbjct: 148 LPWSDCPLNENQTGYVD--------------ECARSSPVDYFWYRETLNISTS--ISDSG 191
Query: 235 PPRWQLTACLVLVIVLLYFSLWKGVKTSGKVVWITATMPYVVLTALLLRGVTLPGAIDGI 294
+W + CL +LY +G++T+GK V+IT+T+PYVVLT L+RG+TL GA +GI
Sbjct: 192 SIQWWMLLCLACAWSVLYMCTIRGIETTGKAVYITSTLPYVVLTIFLIRGLTLKGATNGI 251
Query: 295 RAYLSVDFYRLCEASVWIDAATQVCFSLGVGFGVLIAFSSYNKFTNNCYRDAIVTTSINS 354
+ + L + W+DA QV FS + FG LI+FSSYN NNC +D+++ + IN
Sbjct: 252 VFLFTPNVTELAQPDTWLDAGAQVFFSFSLAFGGLISFSSYNSVHNNCEKDSVIVSIING 311
Query: 355 LTSFSSGFVVFSFLGYMAQKH----------------SVPIGDV---------------- 382
TS VV+S +G+ A + +P G+V
Sbjct: 312 FTSVYVAIVVYSVIGFRATQRYDDCFSTNILTLINGFDLPEGNVTQENFVDMQQRCNASD 371
Query: 383 --------------------AKDGPGLIFIIYPEAIATLPLSSAWAVVFFIMLLTLGIDS 422
A +G GL FI++ EAI +PLS W+V+FFIML LG+ S
Sbjct: 372 PAAYAQLVFQTCDINAFLSEAVEGTGLAFIVFTEAITKMPLSPLWSVLFFIMLFCLGLSS 431
Query: 423 AMGGMESVITGLIDEFQLLHR-HRELFTLFIVLATFLLSLFCVTNGGIYVFTLLDHFAAG 481
G ME V+ L D + + +E+ T I L TFL+ N G Y +LLD +A
Sbjct: 432 MFGNMEGVVVPLQDLRVIPPKWPKEVLTGLICLGTFLIGFIFTLNSGQYWLSLLDSYAGS 491
Query: 482 TSILFGVLIEAIGVAWFYGVGQFSDDIQQMTGQRPSLYWRLCWKLVSPCFLL------FV 535
+L E V + YGV +F+ DI+ M G +P+++W++ W++VSP +L FV
Sbjct: 492 IPLLIIAFCEMFSVVYVYGVDRFNKDIEFMIGHKPNIFWQVTWRVVSPLLMLIIFLFFFV 551
Query: 536 VVVS---IVTFRPPHYGAY------IFPDWANALGWVIATSSMAMVPIYAAYKF----CS 582
V VS + P Y + +P+W + ++A +P YA YK C
Sbjct: 552 VEVSQELTYSIWDPGYEEFPKSQKISYPNWVYVVVVIVAGVPSLTIPGYAIYKLIRNHCQ 611
Query: 583 LPG 585
PG
Sbjct: 612 KPG 614
>gi|194018524 solute carrier family 6, member 18 [Homo sapiens]
Length = 628
Score = 352 bits (904), Expect = 4e-97
Identities = 203/587 (34%), Positives = 308/587 (52%), Gaps = 86/587 (14%)
Query: 59 DRETWGKKIDFLLSVIGFAVDLANVWRFPYLCYKNGGGAFLVPYLLFMVIAGMPLFYMEL 118
+R W K +LLS GFAV L N+WRFPYLC GGGAFL+PY++ +V G+P+F++EL
Sbjct: 17 ERPKWDNKAQYLLSCTGFAVGLGNIWRFPYLCQTYGGGAFLIPYVIALVFEGIPIFHVEL 76
Query: 119 ALGQFNREGAAGVWK-ICPILKGVGFTVILISLYVGFFYNVIIAWALHYLFSSFTTELPW 177
A+GQ R+G+ GVW I P L GVG + +S + +YN I+AW L YL +SF LPW
Sbjct: 77 AIGQRLRKGSVGVWTAISPYLSGVGLGCVTLSFLISLYYNTIVAWVLWYLLNSFQHPLPW 136
Query: 178 IHCNNSWNSPNCSDAHPGDSSGDSSGLNDTFGTTPAAEYFERGVLHLHQSHGIDDLGPPR 237
C N + + + G++ + ++ R L++ + I+D G +
Sbjct: 137 SSCPPDLNR--------------TGFVEECQGSSAVSYFWYRQTLNI--TADINDSGSIQ 180
Query: 238 WQLTACLVLVIVLLYFSLWKGVKTSGKVVWITATMPYVVLTALLLRGVTLPGAIDGIRAY 297
W L CL ++Y + +G++T+GKV++ TA PY+VLT L+RG+TLPGA G+
Sbjct: 181 WWLLICLAASWAVVYMCVIRGIETTGKVIYFTALFPYLVLTIFLIRGLTLPGATKGLIYL 240
Query: 298 LSVDFYRLCEASVWIDAATQVCFSLGVGFGVLIAFSSYNKFTNNCYRDAIVTTSINSLTS 357
+ + + L VW+DAATQ+ FSL + FG IAF+SYN N+C +DA+V +N +TS
Sbjct: 241 FTPNMHILQNPRVWLDAATQIFFSLSLAFGGHIAFASYNSPRNDCQKDAVVIALVNRMTS 300
Query: 358 FSSGFVVFSFLGYMA----------------QKHSVPIGDVAKD---------------- 385
+ VFS LG+ A P +++D
Sbjct: 301 LYASIAVFSVLGFKATNDYEHCLDRNILSLINDFDFPEQSISRDDYPAVLMHLNATWPKR 360
Query: 386 --------------------GPGLIFIIYPEAIATLPLSSAWAVVFFIMLLTLGIDSAMG 425
GPGL F+++ E +P + WA++FF ML TLG+ + G
Sbjct: 361 VAQLPLKACLLEDFLDKSASGPGLAFVVFTETDLHMPGAPVWAMLFFGMLFTLGLSTMFG 420
Query: 426 GMESVITGLIDEFQLLHR--HRELFTLFIVLATFLLSLFCVTNGGIYVFTLLDHFAAGTS 483
+E+VIT L+D +L R +E T + L FL + G Y + D+FAA +
Sbjct: 421 TVEAVITPLLD-VGVLPRWVPKEALTGLVCLVCFLSATCFTLQSGNYWLEIFDNFAASPN 479
Query: 484 ILFGVLIEAIGVAWFYGVGQFSDDIQQMTGQRPSLYWRLCWKLVSPCFL-LFVVVVSIVT 542
+L +E +GV + YG+ +F DDI MTG+RPS YWRL W++VSP L +FV + ++
Sbjct: 480 LLMLAFLEVVGVVYVYGMKRFCDDIAWMTGRRPSPYWRLTWRVVSPLLLTIFVAYIILLF 539
Query: 543 FRPPHYGAY-------------IFPDWANALGWVIATSSMAMVPIYA 576
++P Y A+ ++P WA A +++ + VP+ A
Sbjct: 540 WKPLRYKAWNPKYELFPSRQEKLYPGWARAACVLLSLLPVLWVPVAA 586
>gi|33354281 solute carrier family 6, member 15 isoform 1 [Homo
sapiens]
Length = 730
Score = 328 bits (840), Expect = 1e-89
Identities = 191/599 (31%), Positives = 304/599 (50%), Gaps = 106/599 (17%)
Query: 59 DRETWGKKIDFLLSVIGFAVDLANVWRFPYLCYKNGGGAFLVPYLLFMVIAGMPLFYMEL 118
+R W K+ ++L+ +GF+V L NVWRFPYLC KNGGGA+L+PYL+ +++ G+PLF++EL
Sbjct: 60 ERPAWNSKLQYILAQVGFSVGLGNVWRFPYLCQKNGGGAYLLPYLILLMVIGIPLFFLEL 119
Query: 119 ALGQFNREGAAGVWK-ICPILKGVGFTVILISLYVGFFYNVIIAWALHYLFSSFTTELPW 177
++GQ R G+ GVW I P L G+GF ++ +V +YNVII W+L Y SF LPW
Sbjct: 120 SVGQRIRRGSIGVWNYISPKLGGIGFASCVVCYFVALYYNVIIGWSLFYFSQSFQQPLPW 179
Query: 178 IHC------NNSWNSPNCSDAHPGDSSGDSSGLNDTFGTTPAAEYFERGVLHLHQSHGID 231
C ++++ P C + + Y+ R L++ S I
Sbjct: 180 DQCPLVKNASHTFVEPECEQS------------------SATTYYWYREALNISSS--IS 219
Query: 232 DLGPPRWQLTACLVLVIVLLYFSLWKGVKTSGKVVWITATMPYVVLTALLLRGVTLPGAI 291
+ G W++T CL+ V++ ++ KG+++SGK+++ ++ PYVVL L+R L G+I
Sbjct: 220 ESGGLNWKMTICLLAAWVMVCLAMIKGIQSSGKIIYFSSLFPYVVLICFLIRAFLLNGSI 279
Query: 292 DGIRAYLSVDFYRLCEASVWIDAATQVCFSLGVGFGVLIAFSSYNKFTN----------- 340
DGIR + + E VW +AATQV F+LG+GFG +IAFSSYNK N
Sbjct: 280 DGIRHMFTPKLEIMLEPKVWREAATQVFFALGLGFGGVIAFSSYNKRDNNCHFDAVLVSF 339
Query: 341 -NCYRDAIVTTSINSLTSFSSGFV-----------VFSFL--GYMAQK---HSVPIGDV- 382
N + + T + ++ F + + + FL G ++Q H + + V
Sbjct: 340 INFFTSVLATLVVFAVLGFKANVINEKCITQNSETIMKFLKMGNISQDIIPHHINLSTVT 399
Query: 383 -----------------------------------AKDGPGLIFIIYPEAIATLPLSSAW 407
A G GL FI + EA+ P S W
Sbjct: 400 AEDYHLVYDIIQKVKEEEFPALHLNSCKIEEELNKAVQGTGLAFIAFTEAMTHFPASPFW 459
Query: 408 AVVFFIMLLTLGIDSAMGGMESVITGLIDEFQLLHRHRELFTLFIVLATFLLSLFCVTNG 467
+V+FF+ML+ LG+ S G +E ++T ++D F++ +E+ T+ L F + L V
Sbjct: 460 SVMFFLMLVNLGLGSMFGTIEGIVTPIVDTFKV---RKEILTVICCLLAFCIGLIFVQRS 516
Query: 468 GIYVFTLLDHFAAGTSILFGVLIEAIGVAWFYGVGQFSDDIQQMTGQRPSLYWRLCWKLV 527
G Y T+ D ++A +L V++E I V + YG+ +F +D++ M G PS Y+ WK +
Sbjct: 517 GNYFVTMFDDYSATLPLLIVVILENIAVCFVYGIDKFMEDLKDMLGFAPSRYYYYMWKYI 576
Query: 528 SPCFLLFVVVVSIVT--FRPPHYGAYI----------FPDWANALGWVIATSSMAMVPI 574
SP LL +++ S+V PP Y A+I +P W + + ++ VP+
Sbjct: 577 SPLMLLSLLIASVVNMGLSPPGYNAWIEDKASEEFLSYPTWGLVVCVSLVVFAILPVPV 635
>gi|11181770 solute carrier family 6, member 20 isoform 1 [Homo
sapiens]
Length = 592
Score = 284 bits (726), Expect = 2e-76
Identities = 186/590 (31%), Positives = 297/590 (50%), Gaps = 88/590 (14%)
Query: 60 RETWGKKIDFLLSVIGFAVDLANVWRFPYLCYKNGGGAFLVPYLLFMVIAGMPLFYMELA 119
R W + F+ + I +AV L NVWRFPYLC GGG+FLVPY++ +++ GMPL Y+ELA
Sbjct: 5 RPLWANSLQFVFACISYAVGLGNVWRFPYLCQMYGGGSFLVPYIIMLIVEGMPLLYLELA 64
Query: 120 LGQFNREGAAGVWK-ICPILKGVGFTVILISLYVGFFYNVIIAWALHYLFSSFTTELPWI 178
+GQ R+G+ G W+ I P L GVG +++S ++ +YNVI AWA YLF SF LPW
Sbjct: 65 VGQRMRQGSIGAWRTISPYLSGVGVASVVVSFFLSMYYNVINAWAFWYLFHSFQDPLPWS 124
Query: 179 HCNNSWNSPNCSDAHPGDSSGDSSGLNDTFGTTPAAEYF-ERGVLHLHQSHGIDDLGPPR 237
C +G+ +G ++ + +YF R L++ S + + G +
Sbjct: 125 VC---------------PLNGNHTGYDEECEKASSTQYFWYRKTLNISPS--LQENGGVQ 167
Query: 238 WQLTACLVLVIVLLYFSLWKGVKTSGKVVWITATMPYVVLTALLLRGVTLPGAIDGIRAY 297
W+ CL+L +++Y + +G +++GKVV+ TA++PY VL L+RG+TL GA +G+
Sbjct: 168 WEPALCLLLAWLVVYLCILRGTESTGKVVYFTASLPYCVLIIYLIRGLTLHGATNGLMYM 227
Query: 298 LSVDFYRLCEASVWIDAATQVCFSLGVGFGVLIAFSSYNKFTNNCYRDAIVTTSINSLTS 357
+ +L WI+AATQ+ FSLG+GFG LIAF+SYN+ +NNC + AI+ + INS TS
Sbjct: 228 FTPKIEQLANPKAWINAATQIFFSLGLGFGSLIAFASYNEPSNNCQKHAIIVSLINSFTS 287
Query: 358 FSSGFVVFSFLGYMA--------QKHSVPIGDVAKDGPGLIFIIYPEAIATLPLSSAWAV 409
+ V FS G+ A +K S+ + + G + E + L+SA+
Sbjct: 288 IFASIVTFSIYGFKATFNYENCLKKVSLLLTNTFDLEDGFLTASNLEQVKGY-LASAYPS 346
Query: 410 VFFIMLLTLGIDSAMGGMESVITGLIDEFQLLH---RHRELFTLFIVLATFLL------- 459
+ M + S +++ + G F + ++ E+ L+ VL F+L
Sbjct: 347 KYSEMFPQIKNCSLESELDTAVQGTGLAFIVYTEAIKNMEVSQLWSVLYFFMLLMLGIGS 406
Query: 460 ----------------------------SLFCVTNGGI-YVFT---------LLDHFAAG 481
L C+ N I VFT + + +AA
Sbjct: 407 MLGNTAAILTPLTDSKIISSHLPKEAISGLVCLVNCAIGMVFTMEAGNYWFDIFNDYAAT 466
Query: 482 TSILFGVLIEAIGVAWFYGVGQFSDDIQQMTGQRPSLYWRLCWKLVSPCFLLFVVVVSIV 541
S+L VL+E I V + YG+ +F D++ MTG+ S YW++ W VSP +++VS+
Sbjct: 467 LSLLLIVLVETIAVCYVYGLRRFESDLKAMTGRAVSWYWKVMWAGVSP-----LLIVSLF 521
Query: 542 TFRPPHY---GAYIFPDWANALGWVIATS----SMAMVPIYAAYKFCSLP 584
F Y G + W + G ++ ++A++ + A +P
Sbjct: 522 VFYLSDYILTGTLKYQAWDASQGQLVTKDYPAYALAVIGLLVASSTMCIP 571
>gi|58219014 solute carrier family 6, member 17 [Homo sapiens]
Length = 727
Score = 273 bits (699), Expect = 3e-73
Identities = 139/323 (43%), Positives = 204/323 (63%), Gaps = 17/323 (5%)
Query: 52 QSPVEAQDRETWGKKIDFLLSVIGFAVDLANVWRFPYLCYKNGGGAFLVPYLLFMVIAGM 111
+ ++A+DR W K+ ++L+ IGF+V L N+WRFPYLC KNGGGA+LVPYL+ ++I G+
Sbjct: 52 EEELDAEDRPAWNSKLQYILAQIGFSVGLGNIWRFPYLCQKNGGGAYLVPYLVLLIIIGI 111
Query: 112 PLFYMELALGQFNREGAAGVWK-ICPILKGVGFTVILISLYVGFFYNVIIAWALHYLFSS 170
PLF++ELA+GQ R G+ GVW ICP L G+GF+ ++ L+VG +YNVII W++ Y F S
Sbjct: 112 PLFFLELAVGQRIRRGSIGVWHYICPRLGGIGFSSCIVCLFVGLYYNVIIGWSIFYFFKS 171
Query: 171 FTTELPWIHCNNSWNSPNCSDAHPGDSSGDSSGLNDTFGTTPAAEYF-ERGVLHLHQSHG 229
F LPW C P +G + + + A YF R L + S
Sbjct: 172 FQYPLPWSEC-------------PVVRNGSVAVVEAECEKSSATTYFWYREALDISDS-- 216
Query: 230 IDDLGPPRWQLTACLVLVIVLLYFSLWKGVKTSGKVVWITATMPYVVLTALLLRGVTLPG 289
I + G W++T CL++ ++ ++ KG+++SGKV++ ++ PYVVL L+RG+ L G
Sbjct: 217 ISESGGLNWKMTLCLLVAWSIVGMAVVKGIQSSGKVMYFSSLFPYVVLACFLVRGLLLRG 276
Query: 290 AIDGIRAYLSVDFYRLCEASVWIDAATQVCFSLGVGFGVLIAFSSYNKFTNNCYRDAIVT 349
A+DGI + ++ + VW +AATQV F+LG+GFG +IAFSSYNK NNC+ DA +
Sbjct: 277 AVDGILHMFTPKLDKMLDPQVWREAATQVFFALGLGFGGVIAFSSYNKQDNNCHFDAALV 336
Query: 350 TSINSLTSFSSGFVVFSFLGYMA 372
+ IN TS + VVF+ LG+ A
Sbjct: 337 SFINFFTSVLATLVVFAVLGFKA 359
Score = 124 bits (310), Expect = 3e-28
Identities = 72/206 (34%), Positives = 110/206 (53%), Gaps = 17/206 (8%)
Query: 381 DVAKDGPGLIFIIYPEAIATLPLSSAWAVVFFIMLLTLGIDSAMGGMESVITGLIDEFQL 440
D + G GL FI + EA+ P S W+V+FF+ML+ LG+ S +G M + T +ID F++
Sbjct: 432 DKSVQGTGLAFIAFTEAMTHFPASPFWSVMFFLMLINLGLGSMIGTMAGITTPIIDTFKV 491
Query: 441 LHRHRELFTLFIVLATFLLSLFCVTNGGIYVFTLLDHFAAGTSILFGVLIEAIGVAWFYG 500
+E+FT+ + FL+ L V G Y T+ D ++A + V++E I VAW YG
Sbjct: 492 ---PKEMFTVGCCVFAFLVGLLFVQRSGNYFVTMFDDYSATLPLTLIVILENIAVAWIYG 548
Query: 501 VGQFSDDIQQMTGQRPSLYWRLCWKLVSPCFLLFVVVVSIVTF--RPPHYGAYI------ 552
+F ++ +M G RP ++ WK VSP + + SI+ PP Y A+I
Sbjct: 549 TKKFMQELTEMLGFRPYRFYFYMWKFVSPLCMAVLTTASIIQLGVTPPGYSAWIKEEAAE 608
Query: 553 ----FPDWANALGWVIATSSMAMVPI 574
FP+WA AL +I +A +PI
Sbjct: 609 RYLYFPNWAMAL--LITLIVVATLPI 632
>gi|226437581 solute carrier family 6, member 15 isoform 3 [Homo
sapiens]
Length = 623
Score = 260 bits (664), Expect = 3e-69
Identities = 164/551 (29%), Positives = 266/551 (48%), Gaps = 106/551 (19%)
Query: 107 VIAGMPLFYMELALGQFNREGAAGVWK-ICPILKGVGFTVILISLYVGFFYNVIIAWALH 165
++ G+PLF++EL++GQ R G+ GVW I P L G+GF ++ +V +YNVII W+L
Sbjct: 1 MVIGIPLFFLELSVGQRIRRGSIGVWNYISPKLGGIGFASCVVCYFVALYYNVIIGWSLF 60
Query: 166 YLFSSFTTELPWIHC------NNSWNSPNCSDAHPGDSSGDSSGLNDTFGTTPAAEYFER 219
Y SF LPW C ++++ P C + + Y+ R
Sbjct: 61 YFSQSFQQPLPWDQCPLVKNASHTFVEPECEQS------------------SATTYYWYR 102
Query: 220 GVLHLHQSHGIDDLGPPRWQLTACLVLVIVLLYFSLWKGVKTSGKVVWITATMPYVVLTA 279
L++ S I + G W++T CL+ V++ ++ KG+++SGK+++ ++ PYVVL
Sbjct: 103 EALNISSS--ISESGGLNWKMTICLLAAWVMVCLAMIKGIQSSGKIIYFSSLFPYVVLIC 160
Query: 280 LLLRGVTLPGAIDGIRAYLSVDFYRLCEASVWIDAATQVCFSLGVGFGVLIAFSSYNKFT 339
L+R L G+IDGIR + + E VW +AATQV F+LG+GFG +IAFSSYNK
Sbjct: 161 FLIRAFLLNGSIDGIRHMFTPKLEIMLEPKVWREAATQVFFALGLGFGGVIAFSSYNKRD 220
Query: 340 N------------NCYRDAIVTTSINSLTSFSSGFV-----------VFSFL--GYMAQK 374
N N + + T + ++ F + + + FL G ++Q
Sbjct: 221 NNCHFDAVLVSFINFFTSVLATLVVFAVLGFKANVINEKCITQNSETIMKFLKMGNISQD 280
Query: 375 ---HSVPIGDV------------------------------------AKDGPGLIFIIYP 395
H + + V A G GL FI +
Sbjct: 281 IIPHHINLSTVTAEDYHLVYDIIQKVKEEEFPALHLNSCKIEEELNKAVQGTGLAFIAFT 340
Query: 396 EAIATLPLSSAWAVVFFIMLLTLGIDSAMGGMESVITGLIDEFQLLHRHRELFTLFIVLA 455
EA+ P S W+V+FF+ML+ LG+ S G +E ++T ++D F++ +E+ T+ L
Sbjct: 341 EAMTHFPASPFWSVMFFLMLVNLGLGSMFGTIEGIVTPIVDTFKV---RKEILTVICCLL 397
Query: 456 TFLLSLFCVTNGGIYVFTLLDHFAAGTSILFGVLIEAIGVAWFYGVGQFSDDIQQMTGQR 515
F + L V G Y T+ D ++A +L V++E I V + YG+ +F +D++ M G
Sbjct: 398 AFCIGLIFVQRSGNYFVTMFDDYSATLPLLIVVILENIAVCFVYGIDKFMEDLKDMLGFA 457
Query: 516 PSLYWRLCWKLVSPCFLLFVVVVSIVT--FRPPHYGAYI----------FPDWANALGWV 563
PS Y+ WK +SP LL +++ S+V PP Y A+I +P W +
Sbjct: 458 PSRYYYYMWKYISPLMLLSLLIASVVNMGLSPPGYNAWIEDKASEEFLSYPTWGLVVCVS 517
Query: 564 IATSSMAMVPI 574
+ ++ VP+
Sbjct: 518 LVVFAILPVPV 528
>gi|12408638 solute carrier family 6, member 20 isoform 2 [Homo
sapiens]
Length = 555
Score = 237 bits (604), Expect = 3e-62
Identities = 170/590 (28%), Positives = 274/590 (46%), Gaps = 125/590 (21%)
Query: 60 RETWGKKIDFLLSVIGFAVDLANVWRFPYLCYKNGGGAFLVPYLLFMVIAGMPLFYMELA 119
R W + F+ + I +AV L NVWRFPYLC GGG+FLVPY++ +++ GMPL Y+ELA
Sbjct: 5 RPLWANSLQFVFACISYAVGLGNVWRFPYLCQMYGGGSFLVPYIIMLIVEGMPLLYLELA 64
Query: 120 LGQFNREGAAGVWK-ICPILKGVGFTVILISLYVGFFYNVIIAWALHYLFSSFTTELPWI 178
+GQ R+G+ G W+ I P L GVG +++S ++ +YNVI AWA YLF SF LPW
Sbjct: 65 VGQRMRQGSIGAWRTISPYLSGVGVASVVVSFFLSMYYNVINAWAFWYLFHSFQDPLPWS 124
Query: 179 HCNNSWNSPNCSDAHPGDSSGDSSGLNDTFGTTPAAEYF-ERGVLHLHQSHGIDDLGPPR 237
C +G+ +G ++ + +YF R L++ S + + G +
Sbjct: 125 VC---------------PLNGNHTGYDEECEKASSTQYFWYRKTLNI--SPSLQENGGVQ 167
Query: 238 WQLTACLVLVIVLLYFSLWKGVKTSGKVVWITATMPYVVLTALLLRGVTLPGAIDGIRAY 297
W+ CL+L +++Y + +G +++GK+
Sbjct: 168 WEPALCLLLAWLVVYLCILRGTESTGKI-------------------------------- 195
Query: 298 LSVDFYRLCEASVWIDAATQVCFSLGVGFGVLIAFSSYNKFTNNCYRDAIVTTSINSLTS 357
+L WI+AATQ+ FSLG+GFG LIAF+SYN+ +NNC + AI+ + INS TS
Sbjct: 196 -----EQLANPKAWINAATQIFFSLGLGFGSLIAFASYNEPSNNCQKHAIIVSLINSFTS 250
Query: 358 FSSGFVVFSFLGYMA--------QKHSVPIGDVAKDGPGLIFIIYPEAIATLPLSSAWAV 409
+ V FS G+ A +K S+ + + G + E + L+SA+
Sbjct: 251 IFASIVTFSIYGFKATFNYENCLKKVSLLLTNTFDLEDGFLTASNLEQVKGY-LASAYPS 309
Query: 410 VFFIMLLTLGIDSAMGGMESVITGLIDEFQLLH---RHRELFTLFIVLATFLL------- 459
+ M + S +++ + G F + ++ E+ L+ VL F+L
Sbjct: 310 KYSEMFPQIKNCSLESELDTAVQGTGLAFIVYTEAIKNMEVSQLWSVLYFFMLLMLGIGS 369
Query: 460 ----------------------------SLFCVTNGGI-YVFT---------LLDHFAAG 481
L C+ N I VFT + + +AA
Sbjct: 370 MLGNTAAILTPLTDSKIISSHLPKEAISGLVCLVNCAIGMVFTMEAGNYWFDIFNDYAAT 429
Query: 482 TSILFGVLIEAIGVAWFYGVGQFSDDIQQMTGQRPSLYWRLCWKLVSPCFLLFVVVVSIV 541
S+L VL+E I V + YG+ +F D++ MTG+ S YW++ W VSP +++VS+
Sbjct: 430 LSLLLIVLVETIAVCYVYGLRRFESDLKAMTGRAVSWYWKVMWAGVSP-----LLIVSLF 484
Query: 542 TFRPPHY---GAYIFPDWANALGWVIATS----SMAMVPIYAAYKFCSLP 584
F Y G + W + G ++ ++A++ + A +P
Sbjct: 485 VFYLSDYILTGTLKYQAWDASQGQLVTKDYPAYALAVIGLLVASSTMCIP 534
>gi|197276625 solute carrier family 6 (neurotransmitter transporter,
taurine), member 6 isoform b [Homo sapiens]
Length = 200
Score = 179 bits (455), Expect = 5e-45
Identities = 78/160 (48%), Positives = 109/160 (68%), Gaps = 1/160 (0%)
Query: 60 RETWGKKIDFLLSVIGFAVDLANVWRFPYLCYKNGGGAFLVPYLLFMVIAGMPLFYMELA 119
RE W KIDF+LSV G V L NVWRFPYLCYKNGGGAFL+PY +F+ +G+P+F++E+
Sbjct: 41 REKWSSKIDFVLSVAGGFVGLGNVWRFPYLCYKNGGGAFLIPYFIFLFGSGLPVFFLEII 100
Query: 120 LGQFNREGAAGVW-KICPILKGVGFTVILISLYVGFFYNVIIAWALHYLFSSFTTELPWI 178
+GQ+ EG W KICP+ G+G+ ++I + +Y VI+AWA +YLF SF ELPW
Sbjct: 101 IGQYTSEGGITCWEKICPLFSGIGYASVVIVSLLNVYYIVILAWATYYLFQSFQKELPWA 160
Query: 179 HCNNSWNSPNCSDAHPGDSSGDSSGLNDTFGTTPAAEYFE 218
HCN+SWN+P+C + + ++ T T+P E++E
Sbjct: 161 HCNHSWNTPHCMEDTMRKNKSVWITISSTNFTSPVIEFWE 200
>gi|21361693 solute carrier family 6, member 15 isoform 2 [Homo
sapiens]
Length = 289
Score = 164 bits (415), Expect = 2e-40
Identities = 83/240 (34%), Positives = 136/240 (56%), Gaps = 30/240 (12%)
Query: 59 DRETWGKKIDFLLSVIGFAVDLANVWRFPYLCYKNGGGAFLVPYLLFMVIAGMPLFYMEL 118
+R W K+ ++L+ +GF+V L NVWRFPYLC KNGGGA+L+PYL+ +++ G+PLF++EL
Sbjct: 60 ERPAWNSKLQYILAQVGFSVGLGNVWRFPYLCQKNGGGAYLLPYLILLMVIGIPLFFLEL 119
Query: 119 ALGQFNREGAAGVWK-ICPILKGVGFTVILISLYVGFFYNVIIAWALHYLFSSFTTELPW 177
++GQ R G+ GVW I P L G+GF ++ +V +YNVII W+L Y SF LPW
Sbjct: 120 SVGQRIRRGSIGVWNYISPKLGGIGFASCVVCYFVALYYNVIIGWSLFYFSQSFQQPLPW 179
Query: 178 IHC------NNSWNSPNCSDAHPGDSSGDSSGLNDTFGTTPAAEYFERGVLHLHQSHGID 231
C ++++ P C ++ Y+ R L++ S I
Sbjct: 180 DQCPLVKNASHTFVEPECEQ------------------SSATTYYWYREALNI--SSSIS 219
Query: 232 DLGPPRWQLTACLVLVIVLLYFSLWKGVKTSGKVVWITATMPYVVLTALLLRGVTLPGAI 291
+ G W++T CL+ V++ ++ KG+++SGKV + P+++L + + L ++
Sbjct: 220 ESGGLNWKMTICLLAAWVMVCLAMIKGIQSSGKVSMLE---PFLILLITISGFIPLSNSV 276
>gi|55749589 solute carrier family 6, member 16 [Homo sapiens]
Length = 736
Score = 163 bits (413), Expect = 4e-40
Identities = 94/318 (29%), Positives = 159/318 (50%), Gaps = 25/318 (7%)
Query: 60 RETWGKKIDFLLSVIGFAVDLANVWRFPYLCYKNGGGAFLVPYLLFMVIAGMPLFYMELA 119
R W K +++L+ +GF++ + +WRF YL +GG +F Y+ + + G+PL ++E+A
Sbjct: 103 RPFWSSKTEYILAQVGFSMKPSCLWRFAYLWLNSGGCSFAAIYIFMLFLVGVPLLFLEMA 162
Query: 120 LGQFNREGAAGVWK-ICPILKGVGFTVILISLYVGFFYNVIIAWALHYLFSSFTTELPWI 178
GQ R+G GVWK I P + GVG++ ++ +G ++NV+ +W + Y+ SF +PW
Sbjct: 163 AGQSMRQGGMGVWKIIAPWIGGVGYSSFMVCFILGLYFNVVNSWIIFYMSQSFQFPVPWE 222
Query: 179 HC----NNSWNSPNCSDAHPGDSSGDSSGLNDTFGTTPAAEYFERGVLHLHQSHGIDDLG 234
C N+S P C TTP+ ++ + L S I+D G
Sbjct: 223 KCPLTMNSSGFDPECE------------------RTTPSIYFWYQQA--LKASDRIEDGG 262
Query: 235 PPRWQLTACLVLVIVLLYFSLWKGVKTSGKVVWITATMPYVVLTALLLRGVTLPGAIDGI 294
P + L L L+ + G+K++GKV+++ +P ++ +R + L GA G+
Sbjct: 263 SPVYSLVLPFFLCWCLVGAFMINGLKSTGKVIYVLVLLPCFIIVGFFIRTLLLEGAKFGL 322
Query: 295 RAYLSVDFYRLCEASVWIDAATQVCFSLGVGFGVLIAFSSYNKFTNNCYRDAIVTTSINS 354
+ + + SVW A QV + G+G G + + +SY +NNC DA + + IN
Sbjct: 323 QQLVVAKISDVYNMSVWSLAGGQVLSNTGIGLGSVASLASYMPQSNNCLSDAFLVSVINL 382
Query: 355 LTSFSSGFVVFSFLGYMA 372
LT F LG+ A
Sbjct: 383 LTLLVFTSFNFCVLGFWA 400
Score = 102 bits (253), Expect = 1e-21
Identities = 63/213 (29%), Positives = 105/213 (49%), Gaps = 14/213 (6%)
Query: 383 AKDGPGLIFIIYPEAIATLPLSSAWAVVFFIMLLTLGIDSAMGGMESVITGLIDEFQLLH 442
A +GP F+ + EA++ LP S W+ +FF+MLL +G+ SA+G M+ +IT L D F
Sbjct: 473 ASEGPKFAFLSFVEAMSFLPPSVFWSFIFFLMLLAMGLSSAIGIMQGIITPLQDTFSFFR 532
Query: 443 RHRELFTLFIVLATFLLSLFCVTNGGIYVFTLLDHFAAGTSILFGVLIEAIGVAWFYGVG 502
+H +L + + L F+ LF G Y LL + I+ V+ E + V+W YG
Sbjct: 533 KHTKLLIVGVFLLMFVCGLFFTRPSGSYFIRLLSDYWIVFPIIVVVVFETMAVSWAYGAR 592
Query: 503 QFSDDIQQMTGQRPSLYWRLCWKLVSPCFLLFVVVVSIV--TFRPPHYGAY--------- 551
+F D+ + G S + W + P LL + V +V +P Y ++
Sbjct: 593 RFLADLTILLGHPISPIFGWLWPHLCPVVLLIIFVTMMVHLCMKPITYMSWDSSTSKEVL 652
Query: 552 -IFPDWANALGWVIATSSMAMVPIYAAYKFCSL 583
+P WA L +I ++ ++PI A + +C +
Sbjct: 653 RPYPPWALLL--MITLFAIVILPIPAYFVYCRI 683
Database: hs.faa
Posted date: Aug 4, 2009 4:42 PM
Number of letters in database: 18,247,518
Number of sequences in database: 37,866
Lambda K H
0.326 0.141 0.451
Gapped
Lambda K H
0.267 0.0410 0.140
Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Hits to DB: 23,694,073
Number of Sequences: 37866
Number of extensions: 1030427
Number of successful extensions: 2926
Number of sequences better than 10.0: 30
Number of HSP's better than 10.0 without gapping: 32
Number of HSP's successfully gapped in prelim test: 2
Number of HSP's that attempted gapping in prelim test: 2777
Number of HSP's gapped (non-prelim): 45
length of query: 620
length of database: 18,247,518
effective HSP length: 108
effective length of query: 512
effective length of database: 14,157,990
effective search space: 7248890880
effective search space used: 7248890880
T: 11
A: 40
X1: 15 ( 7.1 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 40 (21.7 bits)
S2: 65 (29.6 bits)
Search results were obtained with NCBI BLAST and RefSeq entries.
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Guide to the Human Genome
Copyright © 2010 by Stewart Scherer. All rights reserved.