Guide to the Human Genome
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Search of human proteins with 4506577

BLASTP 2.2.11 [Jun-05-2005]


Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer, 
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), 
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs",  Nucleic Acids Res. 25:3389-3402.

Query= gi|4506577 RAR-related orphan receptor A isoform c [Homo
sapiens]
         (548 letters)

Database: hs.faa 
           37,866 sequences; 18,247,518 total letters

Searching..................................................done

                                                                 Score    E
Sequences producing significant alignments:                      (bits) Value

gi|4506577 RAR-related orphan receptor A isoform c [Homo sapiens]    1122   0.0  
gi|19743901 RAR-related orphan receptor A isoform b [Homo sapiens]   1014   0.0  
gi|19743905 RAR-related orphan receptor A isoform d [Homo sapiens]    941   0.0  
gi|19743903 RAR-related orphan receptor A isoform a [Homo sapiens]    937   0.0  
gi|19743907 RAR-related orphan receptor B [Homo sapiens]              583   e-166
gi|48255918 RAR-related orphan receptor C isoform b [Homo sapiens]    456   e-128
gi|19743909 RAR-related orphan receptor C isoform a [Homo sapiens]    456   e-128
gi|224177493 nuclear receptor subfamily 1, group D, member 2 iso...   143   5e-34
gi|224177491 nuclear receptor subfamily 1, group D, member 2 iso...   143   5e-34
gi|189491739 nuclear receptor subfamily 2, group C, member 1 iso...   132   6e-31
gi|13430848 nuclear receptor subfamily 1, group D, member 1 [Hom...   129   9e-30
gi|45545405 nuclear receptor subfamily 5, group A, member 2 isof...   124   2e-28
gi|4504343 nuclear receptor subfamily 5, group A, member 2 isofo...   124   2e-28
gi|112181200 retinoic acid receptor, gamma isoform 2 [Homo sapiens]   122   6e-28
gi|4506423 retinoic acid receptor, gamma isoform 1 [Homo sapiens]     122   6e-28
gi|14916494 retinoic acid receptor, beta isoform 1 [Homo sapiens]     122   1e-27
gi|223718064 retinoic acid receptor, alpha isoform 1 [Homo sapiens]   120   3e-27
gi|67459914 retinoic acid receptor, alpha isoform 2 [Homo sapiens]    120   3e-27
gi|4506419 retinoic acid receptor, alpha isoform 1 [Homo sapiens]     120   3e-27
gi|4506755 retinoid X receptor, alpha [Homo sapiens]                  115   8e-26
gi|189491766 nuclear receptor subfamily 2, group C, member 1 iso...   114   2e-25
gi|73808084 nuclear receptor subfamily 2, group C, member 1 isof...   114   2e-25
gi|116284373 peroxisome proliferative activated receptor gamma i...   114   3e-25
gi|20336229 peroxisome proliferative activated receptor gamma is...   114   3e-25
gi|116284368 peroxisome proliferative activated receptor gamma i...   114   3e-25
gi|116284370 peroxisome proliferative activated receptor gamma i...   114   3e-25
gi|5032173 nuclear receptor subfamily 2, group F, member 1 [Homo...   114   3e-25
gi|14149746 nuclear receptor subfamily 2, group F, member 2 isof...   113   4e-25
gi|11415052 retinoid X receptor, beta [Homo sapiens]                  113   4e-25
gi|5902068 retinoid X receptor, gamma isoform a [Homo sapiens]        111   1e-24

>gi|4506577 RAR-related orphan receptor A isoform c [Homo sapiens]
          Length = 548

 Score = 1122 bits (2902), Expect = 0.0
 Identities = 548/548 (100%), Positives = 548/548 (100%)

Query: 1   MNEGAPGDSDLETEARVPWSIMGHCLRTGQARMSATPTPAGEGARSSSTCSSLSRLFWSQ 60
           MNEGAPGDSDLETEARVPWSIMGHCLRTGQARMSATPTPAGEGARSSSTCSSLSRLFWSQ
Sbjct: 1   MNEGAPGDSDLETEARVPWSIMGHCLRTGQARMSATPTPAGEGARSSSTCSSLSRLFWSQ 60

Query: 61  LEHINWDGATAKNFINLREFFSFLLPALRKAQIEIIPCKICGDKSSGIHYGVITCEGCKG 120
           LEHINWDGATAKNFINLREFFSFLLPALRKAQIEIIPCKICGDKSSGIHYGVITCEGCKG
Sbjct: 61  LEHINWDGATAKNFINLREFFSFLLPALRKAQIEIIPCKICGDKSSGIHYGVITCEGCKG 120

Query: 121 FFRRSQQSNATYSCPRQKNCLIDRTSRNRCQHCRLQKCLAVGMSRDAVKFGRMSKKQRDS 180
           FFRRSQQSNATYSCPRQKNCLIDRTSRNRCQHCRLQKCLAVGMSRDAVKFGRMSKKQRDS
Sbjct: 121 FFRRSQQSNATYSCPRQKNCLIDRTSRNRCQHCRLQKCLAVGMSRDAVKFGRMSKKQRDS 180

Query: 181 LYAEVQKHRMQQQQRDHQQQPGEAEPLTPTYNISANGLTELHDDLSNYIDGHTPEGSKAD 240
           LYAEVQKHRMQQQQRDHQQQPGEAEPLTPTYNISANGLTELHDDLSNYIDGHTPEGSKAD
Sbjct: 181 LYAEVQKHRMQQQQRDHQQQPGEAEPLTPTYNISANGLTELHDDLSNYIDGHTPEGSKAD 240

Query: 241 SAVSSFYLDIQPSPDQSGLDINGIKPEPICDYTPASGFFPYCSFTNGETSPTVSMAELEH 300
           SAVSSFYLDIQPSPDQSGLDINGIKPEPICDYTPASGFFPYCSFTNGETSPTVSMAELEH
Sbjct: 241 SAVSSFYLDIQPSPDQSGLDINGIKPEPICDYTPASGFFPYCSFTNGETSPTVSMAELEH 300

Query: 301 LAQNISKSHLETCQYLREELQQITWQTFLQEEIENYQNKQREVMWQLCAIKITEAIQYVV 360
           LAQNISKSHLETCQYLREELQQITWQTFLQEEIENYQNKQREVMWQLCAIKITEAIQYVV
Sbjct: 301 LAQNISKSHLETCQYLREELQQITWQTFLQEEIENYQNKQREVMWQLCAIKITEAIQYVV 360

Query: 361 EFAKRIDGFMELCQNDQIVLLKAGSLEVVFIRMCRAFDSQNNTVYFDGKYASPDVFKSLG 420
           EFAKRIDGFMELCQNDQIVLLKAGSLEVVFIRMCRAFDSQNNTVYFDGKYASPDVFKSLG
Sbjct: 361 EFAKRIDGFMELCQNDQIVLLKAGSLEVVFIRMCRAFDSQNNTVYFDGKYASPDVFKSLG 420

Query: 421 CEDFISFVFEFGKSLCSMHLTEDEIALFSAFVLMSADRSWLQEKVKIEKLQQKIQLALQH 480
           CEDFISFVFEFGKSLCSMHLTEDEIALFSAFVLMSADRSWLQEKVKIEKLQQKIQLALQH
Sbjct: 421 CEDFISFVFEFGKSLCSMHLTEDEIALFSAFVLMSADRSWLQEKVKIEKLQQKIQLALQH 480

Query: 481 VLQKNHREDGILTKLICKVSTLRALCGRHTEKLMAFKAIYPDIVRLHFPPLYKELFTSEF 540
           VLQKNHREDGILTKLICKVSTLRALCGRHTEKLMAFKAIYPDIVRLHFPPLYKELFTSEF
Sbjct: 481 VLQKNHREDGILTKLICKVSTLRALCGRHTEKLMAFKAIYPDIVRLHFPPLYKELFTSEF 540

Query: 541 EPAMQIDG 548
           EPAMQIDG
Sbjct: 541 EPAMQIDG 548


>gi|19743901 RAR-related orphan receptor A isoform b [Homo sapiens]
          Length = 556

 Score = 1014 bits (2621), Expect = 0.0
 Identities = 509/556 (91%), Positives = 513/556 (92%), Gaps = 8/556 (1%)

Query: 1   MNEGAPGDSDLETEARVPWSIMGHCLRTGQARMSATPTPAGEGARSSSTCSSLSRL---F 57
           MNEGAPGDSDLETEARVPWSIMGHCLRTGQARMSATPTPAGEGAR       L  L    
Sbjct: 1   MNEGAPGDSDLETEARVPWSIMGHCLRTGQARMSATPTPAGEGARRDELFGILQILHQCI 60

Query: 58  WSQLEHINWDGATAKNFINLREFFSF-----LLPALRKAQIEIIPCKICGDKSSGIHYGV 112
            S  +     G       N +  +S      +      AQIEIIPCKICGDKSSGIHYGV
Sbjct: 61  LSSGDAFVLTGVCCSWRQNGKPPYSQKEDKEVQTGYMNAQIEIIPCKICGDKSSGIHYGV 120

Query: 113 ITCEGCKGFFRRSQQSNATYSCPRQKNCLIDRTSRNRCQHCRLQKCLAVGMSRDAVKFGR 172
           ITCEGCKGFFRRSQQSNATYSCPRQKNCLIDRTSRNRCQHCRLQKCLAVGMSRDAVKFGR
Sbjct: 121 ITCEGCKGFFRRSQQSNATYSCPRQKNCLIDRTSRNRCQHCRLQKCLAVGMSRDAVKFGR 180

Query: 173 MSKKQRDSLYAEVQKHRMQQQQRDHQQQPGEAEPLTPTYNISANGLTELHDDLSNYIDGH 232
           MSKKQRDSLYAEVQKHRMQQQQRDHQQQPGEAEPLTPTYNISANGLTELHDDLSNYIDGH
Sbjct: 181 MSKKQRDSLYAEVQKHRMQQQQRDHQQQPGEAEPLTPTYNISANGLTELHDDLSNYIDGH 240

Query: 233 TPEGSKADSAVSSFYLDIQPSPDQSGLDINGIKPEPICDYTPASGFFPYCSFTNGETSPT 292
           TPEGSKADSAVSSFYLDIQPSPDQSGLDINGIKPEPICDYTPASGFFPYCSFTNGETSPT
Sbjct: 241 TPEGSKADSAVSSFYLDIQPSPDQSGLDINGIKPEPICDYTPASGFFPYCSFTNGETSPT 300

Query: 293 VSMAELEHLAQNISKSHLETCQYLREELQQITWQTFLQEEIENYQNKQREVMWQLCAIKI 352
           VSMAELEHLAQNISKSHLETCQYLREELQQITWQTFLQEEIENYQNKQREVMWQLCAIKI
Sbjct: 301 VSMAELEHLAQNISKSHLETCQYLREELQQITWQTFLQEEIENYQNKQREVMWQLCAIKI 360

Query: 353 TEAIQYVVEFAKRIDGFMELCQNDQIVLLKAGSLEVVFIRMCRAFDSQNNTVYFDGKYAS 412
           TEAIQYVVEFAKRIDGFMELCQNDQIVLLKAGSLEVVFIRMCRAFDSQNNTVYFDGKYAS
Sbjct: 361 TEAIQYVVEFAKRIDGFMELCQNDQIVLLKAGSLEVVFIRMCRAFDSQNNTVYFDGKYAS 420

Query: 413 PDVFKSLGCEDFISFVFEFGKSLCSMHLTEDEIALFSAFVLMSADRSWLQEKVKIEKLQQ 472
           PDVFKSLGCEDFISFVFEFGKSLCSMHLTEDEIALFSAFVLMSADRSWLQEKVKIEKLQQ
Sbjct: 421 PDVFKSLGCEDFISFVFEFGKSLCSMHLTEDEIALFSAFVLMSADRSWLQEKVKIEKLQQ 480

Query: 473 KIQLALQHVLQKNHREDGILTKLICKVSTLRALCGRHTEKLMAFKAIYPDIVRLHFPPLY 532
           KIQLALQHVLQKNHREDGILTKLICKVSTLRALCGRHTEKLMAFKAIYPDIVRLHFPPLY
Sbjct: 481 KIQLALQHVLQKNHREDGILTKLICKVSTLRALCGRHTEKLMAFKAIYPDIVRLHFPPLY 540

Query: 533 KELFTSEFEPAMQIDG 548
           KELFTSEFEPAMQIDG
Sbjct: 541 KELFTSEFEPAMQIDG 556


>gi|19743905 RAR-related orphan receptor A isoform d [Homo sapiens]
          Length = 468

 Score =  941 bits (2432), Expect = 0.0
 Identities = 460/466 (98%), Positives = 462/466 (99%)

Query: 83  FLLPALRKAQIEIIPCKICGDKSSGIHYGVITCEGCKGFFRRSQQSNATYSCPRQKNCLI 142
           + + A  KAQIEIIPCKICGDKSSGIHYGVITCEGCKGFFRRSQQSNATYSCPRQKNCLI
Sbjct: 3   YFVIAAMKAQIEIIPCKICGDKSSGIHYGVITCEGCKGFFRRSQQSNATYSCPRQKNCLI 62

Query: 143 DRTSRNRCQHCRLQKCLAVGMSRDAVKFGRMSKKQRDSLYAEVQKHRMQQQQRDHQQQPG 202
           DRTSRNRCQHCRLQKCLAVGMSRDAVKFGRMSKKQRDSLYAEVQKHRMQQQQRDHQQQPG
Sbjct: 63  DRTSRNRCQHCRLQKCLAVGMSRDAVKFGRMSKKQRDSLYAEVQKHRMQQQQRDHQQQPG 122

Query: 203 EAEPLTPTYNISANGLTELHDDLSNYIDGHTPEGSKADSAVSSFYLDIQPSPDQSGLDIN 262
           EAEPLTPTYNISANGLTELHDDLSNYIDGHTPEGSKADSAVSSFYLDIQPSPDQSGLDIN
Sbjct: 123 EAEPLTPTYNISANGLTELHDDLSNYIDGHTPEGSKADSAVSSFYLDIQPSPDQSGLDIN 182

Query: 263 GIKPEPICDYTPASGFFPYCSFTNGETSPTVSMAELEHLAQNISKSHLETCQYLREELQQ 322
           GIKPEPICDYTPASGFFPYCSFTNGETSPTVSMAELEHLAQNISKSHLETCQYLREELQQ
Sbjct: 183 GIKPEPICDYTPASGFFPYCSFTNGETSPTVSMAELEHLAQNISKSHLETCQYLREELQQ 242

Query: 323 ITWQTFLQEEIENYQNKQREVMWQLCAIKITEAIQYVVEFAKRIDGFMELCQNDQIVLLK 382
           ITWQTFLQEEIENYQNKQREVMWQLCAIKITEAIQYVVEFAKRIDGFMELCQNDQIVLLK
Sbjct: 243 ITWQTFLQEEIENYQNKQREVMWQLCAIKITEAIQYVVEFAKRIDGFMELCQNDQIVLLK 302

Query: 383 AGSLEVVFIRMCRAFDSQNNTVYFDGKYASPDVFKSLGCEDFISFVFEFGKSLCSMHLTE 442
           AGSLEVVFIRMCRAFDSQNNTVYFDGKYASPDVFKSLGCEDFISFVFEFGKSLCSMHLTE
Sbjct: 303 AGSLEVVFIRMCRAFDSQNNTVYFDGKYASPDVFKSLGCEDFISFVFEFGKSLCSMHLTE 362

Query: 443 DEIALFSAFVLMSADRSWLQEKVKIEKLQQKIQLALQHVLQKNHREDGILTKLICKVSTL 502
           DEIALFSAFVLMSADRSWLQEKVKIEKLQQKIQLALQHVLQKNHREDGILTKLICKVSTL
Sbjct: 363 DEIALFSAFVLMSADRSWLQEKVKIEKLQQKIQLALQHVLQKNHREDGILTKLICKVSTL 422

Query: 503 RALCGRHTEKLMAFKAIYPDIVRLHFPPLYKELFTSEFEPAMQIDG 548
           RALCGRHTEKLMAFKAIYPDIVRLHFPPLYKELFTSEFEPAMQIDG
Sbjct: 423 RALCGRHTEKLMAFKAIYPDIVRLHFPPLYKELFTSEFEPAMQIDG 468


>gi|19743903 RAR-related orphan receptor A isoform a [Homo sapiens]
          Length = 523

 Score =  937 bits (2421), Expect = 0.0
 Identities = 457/458 (99%), Positives = 458/458 (100%)

Query: 91  AQIEIIPCKICGDKSSGIHYGVITCEGCKGFFRRSQQSNATYSCPRQKNCLIDRTSRNRC 150
           +QIEIIPCKICGDKSSGIHYGVITCEGCKGFFRRSQQSNATYSCPRQKNCLIDRTSRNRC
Sbjct: 66  SQIEIIPCKICGDKSSGIHYGVITCEGCKGFFRRSQQSNATYSCPRQKNCLIDRTSRNRC 125

Query: 151 QHCRLQKCLAVGMSRDAVKFGRMSKKQRDSLYAEVQKHRMQQQQRDHQQQPGEAEPLTPT 210
           QHCRLQKCLAVGMSRDAVKFGRMSKKQRDSLYAEVQKHRMQQQQRDHQQQPGEAEPLTPT
Sbjct: 126 QHCRLQKCLAVGMSRDAVKFGRMSKKQRDSLYAEVQKHRMQQQQRDHQQQPGEAEPLTPT 185

Query: 211 YNISANGLTELHDDLSNYIDGHTPEGSKADSAVSSFYLDIQPSPDQSGLDINGIKPEPIC 270
           YNISANGLTELHDDLSNYIDGHTPEGSKADSAVSSFYLDIQPSPDQSGLDINGIKPEPIC
Sbjct: 186 YNISANGLTELHDDLSNYIDGHTPEGSKADSAVSSFYLDIQPSPDQSGLDINGIKPEPIC 245

Query: 271 DYTPASGFFPYCSFTNGETSPTVSMAELEHLAQNISKSHLETCQYLREELQQITWQTFLQ 330
           DYTPASGFFPYCSFTNGETSPTVSMAELEHLAQNISKSHLETCQYLREELQQITWQTFLQ
Sbjct: 246 DYTPASGFFPYCSFTNGETSPTVSMAELEHLAQNISKSHLETCQYLREELQQITWQTFLQ 305

Query: 331 EEIENYQNKQREVMWQLCAIKITEAIQYVVEFAKRIDGFMELCQNDQIVLLKAGSLEVVF 390
           EEIENYQNKQREVMWQLCAIKITEAIQYVVEFAKRIDGFMELCQNDQIVLLKAGSLEVVF
Sbjct: 306 EEIENYQNKQREVMWQLCAIKITEAIQYVVEFAKRIDGFMELCQNDQIVLLKAGSLEVVF 365

Query: 391 IRMCRAFDSQNNTVYFDGKYASPDVFKSLGCEDFISFVFEFGKSLCSMHLTEDEIALFSA 450
           IRMCRAFDSQNNTVYFDGKYASPDVFKSLGCEDFISFVFEFGKSLCSMHLTEDEIALFSA
Sbjct: 366 IRMCRAFDSQNNTVYFDGKYASPDVFKSLGCEDFISFVFEFGKSLCSMHLTEDEIALFSA 425

Query: 451 FVLMSADRSWLQEKVKIEKLQQKIQLALQHVLQKNHREDGILTKLICKVSTLRALCGRHT 510
           FVLMSADRSWLQEKVKIEKLQQKIQLALQHVLQKNHREDGILTKLICKVSTLRALCGRHT
Sbjct: 426 FVLMSADRSWLQEKVKIEKLQQKIQLALQHVLQKNHREDGILTKLICKVSTLRALCGRHT 485

Query: 511 EKLMAFKAIYPDIVRLHFPPLYKELFTSEFEPAMQIDG 548
           EKLMAFKAIYPDIVRLHFPPLYKELFTSEFEPAMQIDG
Sbjct: 486 EKLMAFKAIYPDIVRLHFPPLYKELFTSEFEPAMQIDG 523


>gi|19743907 RAR-related orphan receptor B [Homo sapiens]
          Length = 459

 Score =  583 bits (1503), Expect = e-166
 Identities = 291/458 (63%), Positives = 353/458 (77%), Gaps = 14/458 (3%)

Query: 90  KAQIEIIPCKICGDKSSGIHYGVITCEGCKGFFRRSQQSNATYSCPRQKNCLIDRTSRNR 149
           +AQIE+IPCKICGDKSSGIHYGVITCEGCKGFFRRSQQ+NA+YSCPRQ+NCLIDRT+RNR
Sbjct: 2   RAQIEVIPCKICGDKSSGIHYGVITCEGCKGFFRRSQQNNASYSCPRQRNCLIDRTNRNR 61

Query: 150 CQHCRLQKCLAVGMSRDAVKFGRMSKKQRDSLYAEVQKHRMQQQQRDHQQQPGEAEPLTP 209
           CQHCRLQKCLA+GMSRDAVKFGRMSKKQRDSLYAEVQKH+ Q+ Q   QQQ GEAE L  
Sbjct: 62  CQHCRLQKCLALGMSRDAVKFGRMSKKQRDSLYAEVQKHQ-QRLQEQRQQQSGEAEALAR 120

Query: 210 TYNIS-ANGLTELHDDLSN-YIDGHTPEGSKADSAVSSFYLDI---QPSPDQSGLDINGI 264
            Y+ S +NGL+ L+++ S  Y +GH  +  K++      Y ++   QPSPDQSGLD+ GI
Sbjct: 121 VYSSSISNGLSNLNNETSGTYANGHVIDLPKSEG-----YYNVDSGQPSPDQSGLDMTGI 175

Query: 265 KP---EPICDYTPASGFFPYCSFTNGETSPTVSMAELEHLAQNISKSHLETCQYLREELQ 321
           K    EPI D T     F Y SF NG+ +P ++M E++ +AQNI KSHLETCQY  EEL 
Sbjct: 176 KQIKQEPIYDLTSVPNLFTYSSFNNGQLAPGITMTEIDRIAQNIIKSHLETCQYTMEELH 235

Query: 322 QITWQTFLQEEIENYQNKQREVMWQLCAIKITEAIQYVVEFAKRIDGFMELCQNDQIVLL 381
           Q+ WQT   EEI+ YQ+K RE +WQ CAI+IT AIQYVVEFAKRI GFMELCQNDQI+LL
Sbjct: 236 QLAWQTHTYEEIKAYQSKSREALWQQCAIQITHAIQYVVEFAKRITGFMELCQNDQILLL 295

Query: 382 KAGSLEVVFIRMCRAFDSQNNTVYFDGKYASPDVFKSLGCEDFISFVFEFGKSLCSMHLT 441
           K+G LEVV +RMCRAF+  NNTV F+GKY    +FK+LG +D ++  F+F K+LCS+ LT
Sbjct: 296 KSGCLEVVLVRMCRAFNPLNNTVLFEGKYGGMQMFKALGSDDLVNEAFDFAKNLCSLQLT 355

Query: 442 EDEIALFSAFVLMSADRSWLQEKVKIEKLQQKIQLALQHVLQKNHREDGILTKLICKVST 501
           E+EIALFS+ VL+S DR+WL E  K++KLQ+KI  ALQHV+QKNH +D  L KLI K+ T
Sbjct: 356 EEEIALFSSAVLISPDRAWLIEPRKVQKLQEKIYFALQHVIQKNHLDDETLAKLIAKIPT 415

Query: 502 LRALCGRHTEKLMAFKAIYPDIVRLHFPPLYKELFTSE 539
           + A+C  H EKL  FK  +P+IV   FPPLYKELF  +
Sbjct: 416 ITAVCNLHGEKLQVFKQSHPEIVNTLFPPLYKELFNPD 453


>gi|48255918 RAR-related orphan receptor C isoform b [Homo sapiens]
          Length = 497

 Score =  456 bits (1173), Expect = e-128
 Identities = 242/491 (49%), Positives = 317/491 (64%), Gaps = 41/491 (8%)

Query: 90  KAQIEIIPCKICGDKSSGIHYGVITCEGCKGFFRRSQQSNATYSCPRQKNCLIDRTSRNR 149
           + QIE+IPCKICGDKSSGIHYGVITCEGCKGFFRRSQ+ NA YSC RQ+NC IDRTSRNR
Sbjct: 2   RTQIEVIPCKICGDKSSGIHYGVITCEGCKGFFRRSQRCNAAYSCTRQQNCPIDRTSRNR 61

Query: 150 CQHCRLQKCLAVGMSRDAVKFGRMSKKQRDSLYAEVQKHRMQQQQRDHQ----------- 198
           CQHCRLQKCLA+GMSRDAVKFGRMSKKQRDSL+AEVQK   Q+QQ+  +           
Sbjct: 62  CQHCRLQKCLALGMSRDAVKFGRMSKKQRDSLHAEVQKQLQQRQQQQQEPVVKTPPAGAQ 121

Query: 199 --------------QQPGEAEPLTPTYNISANGLTELHDDLSNYIDG------------- 231
                         Q P  + P  P  +    GL +      +Y +              
Sbjct: 122 GADTLTYTLGLPDGQLPLGSSPDLPEASACPPGLLKASGSGPSYSNNLAKAGLNGASCHL 181

Query: 232 -HTPEGSKADSAVSSFYLDIQPSPDQSGLDINGIKPEPICDYTPASGFFPYCSFTNGETS 290
            ++PE  KA+   S +    Q +PD+ GL     +   + +       +   SF +   +
Sbjct: 182 EYSPERGKAEGRESFYSTGSQLTPDRCGLRFEEHRHPGLGELGQGPDSYGSPSFRSTPEA 241

Query: 291 PTVSMAELEHLAQNISKSHLETCQYLREELQQITWQTFLQEEIENYQNKQREVMWQLCAI 350
           P  S+ E+EHL Q++ KS+ ETCQ   E+L +     F +EE+  YQ K    MW+ CA 
Sbjct: 242 PYASLTEIEHLVQSVCKSYRETCQLRLEDLLRQRSNIFSREEVTGYQRKSMWEMWERCAH 301

Query: 351 KITEAIQYVVEFAKRIDGFMELCQNDQIVLLKAGSLEVVFIRMCRAFDSQNNTVYFDGKY 410
            +TEAIQYVVEFAKR+ GFMELCQNDQIVLLKAG++EVV +RMCRA+++ N TV+F+GKY
Sbjct: 302 HLTEAIQYVVEFAKRLSGFMELCQNDQIVLLKAGAMEVVLVRMCRAYNADNRTVFFEGKY 361

Query: 411 ASPDVFKSLGCEDFISFVFEFGKSLCSMHLTEDEIALFSAFVLMSADRSWLQEKVKIEKL 470
              ++F++LGC + IS +F+F  SL ++H +EDEIAL++A VL++A R  LQEK K+E+L
Sbjct: 362 GGMELFRALGCSELISSIFDFSHSLSALHFSEDEIALYTALVLINAHRPGLQEKRKVEQL 421

Query: 471 QQKIQLALQHVLQKNHREDGILTKLICKVSTLRALCGRHTEKLMAFKAIYPDIVRLHFPP 530
           Q  ++LA  H L K HR+  IL KL  K   LR+LC +H E+L  F+ ++P +V+  FPP
Sbjct: 422 QYNLELAFHHHLCKTHRQ-SILAKLPPK-GKLRSLCSQHVERLQIFQHLHPIVVQAAFPP 479

Query: 531 LYKELFTSEFE 541
           LYKELF++E E
Sbjct: 480 LYKELFSTETE 490


>gi|19743909 RAR-related orphan receptor C isoform a [Homo sapiens]
          Length = 518

 Score =  456 bits (1172), Expect = e-128
 Identities = 242/490 (49%), Positives = 317/490 (64%), Gaps = 41/490 (8%)

Query: 91  AQIEIIPCKICGDKSSGIHYGVITCEGCKGFFRRSQQSNATYSCPRQKNCLIDRTSRNRC 150
           +QIE+IPCKICGDKSSGIHYGVITCEGCKGFFRRSQ+ NA YSC RQ+NC IDRTSRNRC
Sbjct: 24  SQIEVIPCKICGDKSSGIHYGVITCEGCKGFFRRSQRCNAAYSCTRQQNCPIDRTSRNRC 83

Query: 151 QHCRLQKCLAVGMSRDAVKFGRMSKKQRDSLYAEVQKHRMQQQQRDHQ------------ 198
           QHCRLQKCLA+GMSRDAVKFGRMSKKQRDSL+AEVQK   Q+QQ+  +            
Sbjct: 84  QHCRLQKCLALGMSRDAVKFGRMSKKQRDSLHAEVQKQLQQRQQQQQEPVVKTPPAGAQG 143

Query: 199 -------------QQPGEAEPLTPTYNISANGLTELHDDLSNYIDG-------------- 231
                        Q P  + P  P  +    GL +      +Y +               
Sbjct: 144 ADTLTYTLGLPDGQLPLGSSPDLPEASACPPGLLKASGSGPSYSNNLAKAGLNGASCHLE 203

Query: 232 HTPEGSKADSAVSSFYLDIQPSPDQSGLDINGIKPEPICDYTPASGFFPYCSFTNGETSP 291
           ++PE  KA+   S +    Q +PD+ GL     +   + +       +   SF +   +P
Sbjct: 204 YSPERGKAEGRESFYSTGSQLTPDRCGLRFEEHRHPGLGELGQGPDSYGSPSFRSTPEAP 263

Query: 292 TVSMAELEHLAQNISKSHLETCQYLREELQQITWQTFLQEEIENYQNKQREVMWQLCAIK 351
             S+ E+EHL Q++ KS+ ETCQ   E+L +     F +EE+  YQ K    MW+ CA  
Sbjct: 264 YASLTEIEHLVQSVCKSYRETCQLRLEDLLRQRSNIFSREEVTGYQRKSMWEMWERCAHH 323

Query: 352 ITEAIQYVVEFAKRIDGFMELCQNDQIVLLKAGSLEVVFIRMCRAFDSQNNTVYFDGKYA 411
           +TEAIQYVVEFAKR+ GFMELCQNDQIVLLKAG++EVV +RMCRA+++ N TV+F+GKY 
Sbjct: 324 LTEAIQYVVEFAKRLSGFMELCQNDQIVLLKAGAMEVVLVRMCRAYNADNRTVFFEGKYG 383

Query: 412 SPDVFKSLGCEDFISFVFEFGKSLCSMHLTEDEIALFSAFVLMSADRSWLQEKVKIEKLQ 471
             ++F++LGC + IS +F+F  SL ++H +EDEIAL++A VL++A R  LQEK K+E+LQ
Sbjct: 384 GMELFRALGCSELISSIFDFSHSLSALHFSEDEIALYTALVLINAHRPGLQEKRKVEQLQ 443

Query: 472 QKIQLALQHVLQKNHREDGILTKLICKVSTLRALCGRHTEKLMAFKAIYPDIVRLHFPPL 531
             ++LA  H L K HR+  IL KL  K   LR+LC +H E+L  F+ ++P +V+  FPPL
Sbjct: 444 YNLELAFHHHLCKTHRQ-SILAKLPPK-GKLRSLCSQHVERLQIFQHLHPIVVQAAFPPL 501

Query: 532 YKELFTSEFE 541
           YKELF++E E
Sbjct: 502 YKELFSTETE 511


>gi|224177493 nuclear receptor subfamily 1, group D, member 2
           isoform 2 [Homo sapiens]
          Length = 504

 Score =  143 bits (360), Expect = 5e-34
 Identities = 77/182 (42%), Positives = 120/182 (65%), Gaps = 2/182 (1%)

Query: 338 NKQREVMWQLCAIKITEAIQYVVEFAKRIDGFMELCQNDQIVLLKAGSLEVVFIRMCRAF 397
           +K    +W+  ++  T A++ VVEFAKRI GF +L Q+DQ+ LLKAG+ EV+ +R    F
Sbjct: 320 HKSGHEIWEEFSMSFTPAVKEVVEFAKRIPGFRDLSQHDQVNLLKAGTFEVLMVRFASLF 379

Query: 398 DSQNNTVYF-DGKYASPDVFKSLGCEDFISFVFEFGKSLCSMHLTEDEIALFSAFVLMSA 456
           D++  TV F  GK  S D   S+G  D ++ +FEF + L ++ L+++E++LF+A VL+SA
Sbjct: 380 DAKERTVTFLSGKKYSVDDLHSMGAGDLLNSMFEFSEKLNALQLSDEEMSLFTAVVLVSA 439

Query: 457 DRSWLQEKVKIEKLQQKIQLALQHVLQKNH-REDGILTKLICKVSTLRALCGRHTEKLMA 515
           DRS ++    +E LQ+ +  AL+ ++ KNH  E  I TKL+ K+  LR+L   H+E+L+A
Sbjct: 440 DRSGIENVNSVEALQETLIRALRTLIMKNHPNEASIFTKLLLKLPDLRSLNNMHSEELLA 499

Query: 516 FK 517
           FK
Sbjct: 500 FK 501



 Score =  124 bits (312), Expect = 2e-28
 Identities = 59/109 (54%), Positives = 75/109 (68%), Gaps = 4/109 (3%)

Query: 95  IIPCKICGDKSSGIHYGVITCEGCKGFFRRSQQSNATYS-CPRQKNCLIDRTSRNRCQHC 153
           ++ CK+CGD +SG HYGV  CEGCKGFFRRS Q N  Y  C + +NC I R +RNRCQ C
Sbjct: 25  VLLCKVCGDVASGFHYGVHACEGCKGFFRRSIQQNIQYKKCLKNENCSIMRMNRNRCQQC 84

Query: 154 RLQKCLAVGMSRDAVKFGRMSKKQRDSLYAEVQ---KHRMQQQQRDHQQ 199
           R +KCL+VGMSRDAV+FGR+ K+++  +  E+Q   K  M  Q   H Q
Sbjct: 85  RFKKCLSVGMSRDAVRFGRIPKREKQRMLIEMQSAMKTMMNSQFSGHLQ 133


>gi|224177491 nuclear receptor subfamily 1, group D, member 2
           isoform 1 [Homo sapiens]
          Length = 579

 Score =  143 bits (360), Expect = 5e-34
 Identities = 77/182 (42%), Positives = 120/182 (65%), Gaps = 2/182 (1%)

Query: 338 NKQREVMWQLCAIKITEAIQYVVEFAKRIDGFMELCQNDQIVLLKAGSLEVVFIRMCRAF 397
           +K    +W+  ++  T A++ VVEFAKRI GF +L Q+DQ+ LLKAG+ EV+ +R    F
Sbjct: 395 HKSGHEIWEEFSMSFTPAVKEVVEFAKRIPGFRDLSQHDQVNLLKAGTFEVLMVRFASLF 454

Query: 398 DSQNNTVYF-DGKYASPDVFKSLGCEDFISFVFEFGKSLCSMHLTEDEIALFSAFVLMSA 456
           D++  TV F  GK  S D   S+G  D ++ +FEF + L ++ L+++E++LF+A VL+SA
Sbjct: 455 DAKERTVTFLSGKKYSVDDLHSMGAGDLLNSMFEFSEKLNALQLSDEEMSLFTAVVLVSA 514

Query: 457 DRSWLQEKVKIEKLQQKIQLALQHVLQKNH-REDGILTKLICKVSTLRALCGRHTEKLMA 515
           DRS ++    +E LQ+ +  AL+ ++ KNH  E  I TKL+ K+  LR+L   H+E+L+A
Sbjct: 515 DRSGIENVNSVEALQETLIRALRTLIMKNHPNEASIFTKLLLKLPDLRSLNNMHSEELLA 574

Query: 516 FK 517
           FK
Sbjct: 575 FK 576



 Score =  124 bits (312), Expect = 2e-28
 Identities = 59/109 (54%), Positives = 75/109 (68%), Gaps = 4/109 (3%)

Query: 95  IIPCKICGDKSSGIHYGVITCEGCKGFFRRSQQSNATYS-CPRQKNCLIDRTSRNRCQHC 153
           ++ CK+CGD +SG HYGV  CEGCKGFFRRS Q N  Y  C + +NC I R +RNRCQ C
Sbjct: 100 VLLCKVCGDVASGFHYGVHACEGCKGFFRRSIQQNIQYKKCLKNENCSIMRMNRNRCQQC 159

Query: 154 RLQKCLAVGMSRDAVKFGRMSKKQRDSLYAEVQ---KHRMQQQQRDHQQ 199
           R +KCL+VGMSRDAV+FGR+ K+++  +  E+Q   K  M  Q   H Q
Sbjct: 160 RFKKCLSVGMSRDAVRFGRIPKREKQRMLIEMQSAMKTMMNSQFSGHLQ 208


>gi|189491739 nuclear receptor subfamily 2, group C, member 1
           isoform a [Homo sapiens]
          Length = 603

 Score =  132 bits (333), Expect = 6e-31
 Identities = 129/481 (26%), Positives = 217/481 (45%), Gaps = 71/481 (14%)

Query: 98  CKICGDKSSGIHYGVITCEGCKGFFRRSQQSNATYSCPRQKNCLIDRTSRNRCQHCRLQK 157
           C +CGDK+SG HYG +TCEGCKGFF+RS + N  YSC   K+C+I++  RNRCQ+CRLQ+
Sbjct: 113 CVVCGDKASGRHYGAVTCEGCKGFFKRSIRKNLVYSCRGSKDCIINKHHRNRCQYCRLQR 172

Query: 158 CLAVGMSRDAVKFGR----MSKKQRDSLYAEVQKHRMQQQQRDHQQQPGEAEP--LTPTY 211
           C+A GM +D+V+  R    +S+++  +  A  +K  +++  R     P  A P  +T + 
Sbjct: 173 CIAFGMKQDSVQCERKPIEVSREKSSNCAASTEKIYIRKDLR----SPLTATPTFVTDSE 228

Query: 212 NISANGLTELHDDLSNYIDGHTPEGSKADSAV-------------SSFYLDIQPSPDQSG 258
           +  + GL     D   +++ H P G K +SAV              S   ++  S    G
Sbjct: 229 STRSTGLL----DSGMFMNIH-PSGVKTESAVLMTSDKAESCQGDLSTLANVVTSLANLG 283

Query: 259 --LDINGIKPEPICDYTPASGFFPYCSFTNGETSPTVSMAELEHLAQNISKSHLETCQY- 315
              D++    E     + ++     C F   +T+  VS A  + LA+ ++      CQ  
Sbjct: 284 KTKDLSQNSNEMSMIESLSNDDTSLCEFQEMQTNGDVSRA-FDTLAKALNPGESTACQSS 342

Query: 316 ---LREELQQITWQTFLQEEIENYQNKQREVMWQL-CAIKITEA--------IQYVVEFA 363
              +   +  IT  + +     NY  K+  ++     A ++T          + Y+ E A
Sbjct: 343 VAGMEGSVHLITGDSSI-----NYTEKEGPLLSDSHVAFRLTMPSPMPEYLNVHYIGESA 397

Query: 364 KR-----------IDGFMELCQNDQIVLLKAGSLEVVFIRMCRAFDSQN---------NT 403
            R           I  F  L Q + I L+KA   E+  + + + +   N         N 
Sbjct: 398 SRLLFLSMHWALSIPSFQALGQENSISLVKAYWNELFTLGLAQCWQVMNVATILATFVNC 457

Query: 404 VYFDGKYASPDVFKSLGCEDFISFVFEFGKSLCSMHLTEDEIALFSAFVLMSADRSWLQE 463
           ++   +       +     + I  + EF  S+  + +   E A   A VL S D   L+ 
Sbjct: 458 LHNSLQQDKMSTERRKLLMEHIFKLQEFCNSMVKLCIDGYEYAYLKAIVLFSPDHPSLEN 517

Query: 464 KVKIEKLQQKIQLALQHVLQKNHREDGI-LTKLICKVSTLRALCGRHTEKLMAFKAIYPD 522
             +IEK Q+K  +  Q  + K + +D   L++L+ ++  LR +    TE+L  FK +  +
Sbjct: 518 MEQIEKFQEKAYVEFQDYITKTYPDDTYRLSRLLLRLPALRLMNATITEELF-FKGLIGN 576

Query: 523 I 523
           I
Sbjct: 577 I 577


>gi|13430848 nuclear receptor subfamily 1, group D, member 1 [Homo
           sapiens]
          Length = 614

 Score =  129 bits (323), Expect = 9e-30
 Identities = 73/179 (40%), Positives = 103/179 (57%), Gaps = 13/179 (7%)

Query: 34  SATPTPAGEGARSSSTCSSLSRLFWSQLEHINWDGATAKNFINLREFFSFLLPALRKAQI 93
           S  P+ + +G+ SSS+ SS S   +       ++G+   +     E  S + P+   + I
Sbjct: 70  SIPPSLSDDGSPSSSSSSSSSSSSF-------YNGSPPGSLQVAMEDSSRVSPSKSTSNI 122

Query: 94  E-----IIPCKICGDKSSGIHYGVITCEGCKGFFRRSQQSNATYS-CPRQKNCLIDRTSR 147
                 ++ CK+CGD +SG HYGV  CEGCKGFFRRS Q N  Y  C + +NC I R +R
Sbjct: 123 TKLNGMVLLCKVCGDVASGFHYGVHACEGCKGFFRRSIQQNIQYKRCLKNENCSIVRINR 182

Query: 148 NRCQHCRLQKCLAVGMSRDAVKFGRMSKKQRDSLYAEVQKHRMQQQQRDHQQQPGEAEP 206
           NRCQ CR +KCL+VGMSRDAV+FGR+ K+++  + AE+Q        +   Q P E  P
Sbjct: 183 NRCQQCRFKKCLSVGMSRDAVRFGRIPKREKQRMLAEMQSAMNLANNQLSSQCPLETSP 241



 Score =  128 bits (321), Expect = 2e-29
 Identities = 70/176 (39%), Positives = 112/176 (63%), Gaps = 2/176 (1%)

Query: 344 MWQLCAIKITEAIQYVVEFAKRIDGFMELCQNDQIVLLKAGSLEVVFIRMCRAFDSQNNT 403
           +W+  ++  T A++ VVEFAK I GF +L Q+DQ+ LLKAG+ EV+ +R    F+ ++ T
Sbjct: 435 IWEDFSMSFTPAVREVVEFAKHIPGFRDLSQHDQVTLLKAGTFEVLMVRFASLFNVKDQT 494

Query: 404 VYFDGKYA-SPDVFKSLGCEDFISFVFEFGKSLCSMHLTEDEIALFSAFVLMSADRSWLQ 462
           V F  +   S     ++G  D +S +F+F + L S+ LTE+E+ LF+A VL+SADRS ++
Sbjct: 495 VMFLSRTTYSLQELGAMGMGDLLSAMFDFSEKLNSLALTEEELGLFTAVVLVSADRSGME 554

Query: 463 EKVKIEKLQQKIQLALQHVLQKNH-REDGILTKLICKVSTLRALCGRHTEKLMAFK 517
               +E+LQ+ +  AL+ ++ KN   E    TKL+ K+  LR L   H+EKL++F+
Sbjct: 555 NSASVEQLQETLLRALRALVLKNRPLETSRFTKLLLKLPDLRTLNNMHSEKLLSFR 610


>gi|45545405 nuclear receptor subfamily 5, group A, member 2 isoform
           1 [Homo sapiens]
          Length = 541

 Score =  124 bits (311), Expect = 2e-28
 Identities = 113/450 (25%), Positives = 192/450 (42%), Gaps = 33/450 (7%)

Query: 98  CKICGDKSSGIHYGVITCEGCKGFFRRSQQSNATYSCPRQKNCLIDRTSRNRCQHCRLQK 157
           C +CGDK SG HYG++TCE CKGFF+R+ Q+N  Y+C   +NC ID+T R RC +CR QK
Sbjct: 86  CPVCGDKVSGYHYGLLTCESCKGFFKRTVQNNKRYTCIENQNCQIDKTQRKRCPYCRFQK 145

Query: 158 CLAVGMSRDAV----------KFGRMSK-----KQRDSLYAEVQKHRMQQQQRDHQQQPG 202
           CL+VGM  +AV          KFG M K     KQ+          +++   +  Q  P 
Sbjct: 146 CLSVGMKLEAVRADRMRGGRNKFGPMYKRDRALKQQKKALIRANGLKLEAMSQVIQAMPS 205

Query: 203 EAEPLTPTYNI--SANGLTELHDDLSNYIDGHTPEGSKADSAVSSFYLDIQPSPDQSGLD 260
           +    +   NI  ++ GL   H  L       +P  +   S     +  +Q         
Sbjct: 206 DLTISSAIQNIHSASKGLPLNHAALPPTDYDRSPFVTSPISMTMPPHGSLQGYQTYGHFP 265

Query: 261 INGIKPEPICDYTPASGFFPYCSFTNGETSPTVSMAELEHLAQNISKSHLETCQYLREEL 320
              IK E    YT +       S+   ++  T S A + HL   + K   +      E  
Sbjct: 266 SRAIKSEYPDPYTSSPESIMGYSYM--DSYQTSSPASIPHLILELLKCEPD------EPQ 317

Query: 321 QQITWQTFLQEEIENYQNKQREVMWQLCAIKITEAIQYVVEFAKRIDGFMELCQNDQIVL 380
            Q     +LQ+E  N    ++   + L      + +  +VE+A+    F EL  +DQ+ L
Sbjct: 318 VQAKIMAYLQQEQANRSKHEKLSTFGLMCKMADQTLFSIVEWARSSIFFRELKVDDQMKL 377

Query: 381 LKAGSLEVVFIRMC--RAFDSQNNTVYF-DGKYASPDVFKSLG---CEDFISFVFEFGKS 434
           L+    E++ +     +    +  +++   G+     +  S       + +S   E    
Sbjct: 378 LQNCWSELLILDHIYRQVVHGKEGSIFLVTGQQVDYSIIASQAGATLNNLMSHAQELVAK 437

Query: 435 LCSMHLTEDEIALFSAFVLMSADRSWLQEKVKIEKLQQKIQLALQHVLQKNH-REDGILT 493
           L S+   + E       VL S D   L+    +E +Q+++  AL      N+ ++     
Sbjct: 438 LRSLQFDQREFVCLKFLVLFSLDVKNLENFQLVEGVQEQVNAALLDYTMCNYPQQTEKFG 497

Query: 494 KLICKVSTLRALCGRHTEKLMAFKAIYPDI 523
           +L+ ++  +RA+     E+ + +K +  D+
Sbjct: 498 QLLLRLPEIRAI-SMQAEEYLYYKHLNGDV 526


>gi|4504343 nuclear receptor subfamily 5, group A, member 2 isoform
           2 [Homo sapiens]
          Length = 495

 Score =  124 bits (311), Expect = 2e-28
 Identities = 113/450 (25%), Positives = 192/450 (42%), Gaps = 33/450 (7%)

Query: 98  CKICGDKSSGIHYGVITCEGCKGFFRRSQQSNATYSCPRQKNCLIDRTSRNRCQHCRLQK 157
           C +CGDK SG HYG++TCE CKGFF+R+ Q+N  Y+C   +NC ID+T R RC +CR QK
Sbjct: 40  CPVCGDKVSGYHYGLLTCESCKGFFKRTVQNNKRYTCIENQNCQIDKTQRKRCPYCRFQK 99

Query: 158 CLAVGMSRDAV----------KFGRMSK-----KQRDSLYAEVQKHRMQQQQRDHQQQPG 202
           CL+VGM  +AV          KFG M K     KQ+          +++   +  Q  P 
Sbjct: 100 CLSVGMKLEAVRADRMRGGRNKFGPMYKRDRALKQQKKALIRANGLKLEAMSQVIQAMPS 159

Query: 203 EAEPLTPTYNI--SANGLTELHDDLSNYIDGHTPEGSKADSAVSSFYLDIQPSPDQSGLD 260
           +    +   NI  ++ GL   H  L       +P  +   S     +  +Q         
Sbjct: 160 DLTISSAIQNIHSASKGLPLNHAALPPTDYDRSPFVTSPISMTMPPHGSLQGYQTYGHFP 219

Query: 261 INGIKPEPICDYTPASGFFPYCSFTNGETSPTVSMAELEHLAQNISKSHLETCQYLREEL 320
              IK E    YT +       S+   ++  T S A + HL   + K   +      E  
Sbjct: 220 SRAIKSEYPDPYTSSPESIMGYSYM--DSYQTSSPASIPHLILELLKCEPD------EPQ 271

Query: 321 QQITWQTFLQEEIENYQNKQREVMWQLCAIKITEAIQYVVEFAKRIDGFMELCQNDQIVL 380
            Q     +LQ+E  N    ++   + L      + +  +VE+A+    F EL  +DQ+ L
Sbjct: 272 VQAKIMAYLQQEQANRSKHEKLSTFGLMCKMADQTLFSIVEWARSSIFFRELKVDDQMKL 331

Query: 381 LKAGSLEVVFIRMC--RAFDSQNNTVYF-DGKYASPDVFKSLG---CEDFISFVFEFGKS 434
           L+    E++ +     +    +  +++   G+     +  S       + +S   E    
Sbjct: 332 LQNCWSELLILDHIYRQVVHGKEGSIFLVTGQQVDYSIIASQAGATLNNLMSHAQELVAK 391

Query: 435 LCSMHLTEDEIALFSAFVLMSADRSWLQEKVKIEKLQQKIQLALQHVLQKNH-REDGILT 493
           L S+   + E       VL S D   L+    +E +Q+++  AL      N+ ++     
Sbjct: 392 LRSLQFDQREFVCLKFLVLFSLDVKNLENFQLVEGVQEQVNAALLDYTMCNYPQQTEKFG 451

Query: 494 KLICKVSTLRALCGRHTEKLMAFKAIYPDI 523
           +L+ ++  +RA+     E+ + +K +  D+
Sbjct: 452 QLLLRLPEIRAI-SMQAEEYLYYKHLNGDV 480


>gi|112181200 retinoic acid receptor, gamma isoform 2 [Homo sapiens]
          Length = 443

 Score =  122 bits (307), Expect = 6e-28
 Identities = 52/81 (64%), Positives = 64/81 (79%)

Query: 97  PCKICGDKSSGIHYGVITCEGCKGFFRRSQQSNATYSCPRQKNCLIDRTSRNRCQHCRLQ 156
           PC +C DKSSG HYGV +CEGCKGFFRRS Q N  Y+C R KNC+I++ +RNRCQ+CRLQ
Sbjct: 78  PCFVCNDKSSGYHYGVSSCEGCKGFFRRSIQKNMVYTCHRDKNCIINKVTRNRCQYCRLQ 137

Query: 157 KCLAVGMSRDAVKFGRMSKKQ 177
           KC  VGMS++AV+  R  KK+
Sbjct: 138 KCFEVGMSKEAVRNDRNKKKK 158



 Score = 94.4 bits (233), Expect = 2e-19
 Identities = 67/241 (27%), Positives = 117/241 (48%), Gaps = 12/241 (4%)

Query: 297 ELEHLAQNISKSHLETCQYLREELQQITWQTFLQEEIENYQNKQREVMWQLCAIKITEAI 356
           +LE L   +SK+H ET   L + L + T  +     ++         +W   +   T+ I
Sbjct: 174 QLEELITKVSKAHQETFPSLCQ-LGKYTTNSSADHRVQLDLG-----LWDKFSELATKCI 227

Query: 357 QYVVEFAKRIDGFMELCQNDQIVLLKAGSLEVVFIRMCRAFDSQNNTVYF-DGKYASPDV 415
             +VEFAKR+ GF  L   DQI LLKA  L+++ +R+C  +  + +T+ F DG   +   
Sbjct: 228 IKIVEFAKRLPGFTGLSIADQITLLKAACLDILMLRICTRYTPEQDTMTFSDGLTLNRTQ 287

Query: 416 FKSLGCEDFISFVFEFGKSLCSMHLTEDEIALFSAFVLMSADRSWLQEKVKIEKLQQKIQ 475
             + G       VF F   L  + + + E  L SA  L+  DR  L+E  K++KLQ+ + 
Sbjct: 288 MHNAGFGPLTDLVFAFAGQLLPLEMDDTETGLLSAICLICGDRMDLEEPEKVDKLQEPLL 347

Query: 476 LALQ-HVLQKNHREDGILTKLICKVSTLRALCGRHTEKLMAFKAIYPDIVRLHFPPLYKE 534
            AL+ +  ++   +  +  +++ K++ LR +  +  E+ +  K   P       PPL +E
Sbjct: 348 EALRLYARRRRPSQPYMFPRMLMKITDLRGISTKGAERAITLKMEIPG----PMPPLIRE 403

Query: 535 L 535
           +
Sbjct: 404 M 404


>gi|4506423 retinoic acid receptor, gamma isoform 1 [Homo sapiens]
          Length = 454

 Score =  122 bits (307), Expect = 6e-28
 Identities = 52/81 (64%), Positives = 64/81 (79%)

Query: 97  PCKICGDKSSGIHYGVITCEGCKGFFRRSQQSNATYSCPRQKNCLIDRTSRNRCQHCRLQ 156
           PC +C DKSSG HYGV +CEGCKGFFRRS Q N  Y+C R KNC+I++ +RNRCQ+CRLQ
Sbjct: 89  PCFVCNDKSSGYHYGVSSCEGCKGFFRRSIQKNMVYTCHRDKNCIINKVTRNRCQYCRLQ 148

Query: 157 KCLAVGMSRDAVKFGRMSKKQ 177
           KC  VGMS++AV+  R  KK+
Sbjct: 149 KCFEVGMSKEAVRNDRNKKKK 169



 Score = 94.4 bits (233), Expect = 2e-19
 Identities = 67/241 (27%), Positives = 117/241 (48%), Gaps = 12/241 (4%)

Query: 297 ELEHLAQNISKSHLETCQYLREELQQITWQTFLQEEIENYQNKQREVMWQLCAIKITEAI 356
           +LE L   +SK+H ET   L + L + T  +     ++         +W   +   T+ I
Sbjct: 185 QLEELITKVSKAHQETFPSLCQ-LGKYTTNSSADHRVQLDLG-----LWDKFSELATKCI 238

Query: 357 QYVVEFAKRIDGFMELCQNDQIVLLKAGSLEVVFIRMCRAFDSQNNTVYF-DGKYASPDV 415
             +VEFAKR+ GF  L   DQI LLKA  L+++ +R+C  +  + +T+ F DG   +   
Sbjct: 239 IKIVEFAKRLPGFTGLSIADQITLLKAACLDILMLRICTRYTPEQDTMTFSDGLTLNRTQ 298

Query: 416 FKSLGCEDFISFVFEFGKSLCSMHLTEDEIALFSAFVLMSADRSWLQEKVKIEKLQQKIQ 475
             + G       VF F   L  + + + E  L SA  L+  DR  L+E  K++KLQ+ + 
Sbjct: 299 MHNAGFGPLTDLVFAFAGQLLPLEMDDTETGLLSAICLICGDRMDLEEPEKVDKLQEPLL 358

Query: 476 LALQ-HVLQKNHREDGILTKLICKVSTLRALCGRHTEKLMAFKAIYPDIVRLHFPPLYKE 534
            AL+ +  ++   +  +  +++ K++ LR +  +  E+ +  K   P       PPL +E
Sbjct: 359 EALRLYARRRRPSQPYMFPRMLMKITDLRGISTKGAERAITLKMEIPG----PMPPLIRE 414

Query: 535 L 535
           +
Sbjct: 415 M 415


>gi|14916494 retinoic acid receptor, beta isoform 1 [Homo sapiens]
          Length = 448

 Score =  122 bits (305), Expect = 1e-27
 Identities = 54/100 (54%), Positives = 69/100 (69%)

Query: 97  PCKICGDKSSGIHYGVITCEGCKGFFRRSQQSNATYSCPRQKNCLIDRTSRNRCQHCRLQ 156
           PC +C DKSSG HYGV  CEGCKGFFRRS Q N  Y+C R KNC+I++ +RNRCQ+CRLQ
Sbjct: 80  PCFVCQDKSSGYHYGVSACEGCKGFFRRSIQKNMIYTCHRDKNCVINKVTRNRCQYCRLQ 139

Query: 157 KCLAVGMSRDAVKFGRMSKKQRDSLYAEVQKHRMQQQQRD 196
           KC  VGMS+++V+  R  KK+  S     + + M  +  D
Sbjct: 140 KCFEVGMSKESVRNDRNKKKKETSKQECTESYEMTAELDD 179



 Score =  100 bits (250), Expect = 3e-21
 Identities = 68/242 (28%), Positives = 121/242 (50%), Gaps = 12/242 (4%)

Query: 296 AELEHLAQNISKSHLETCQYLREELQQITWQTFLQEEIENYQNKQREVMWQLCAIKITEA 355
           AEL+ L + I K+H ET   L +  +  T          +++ +    +W   +   T+ 
Sbjct: 175 AELDDLTEKIRKAHQETFPSLCQLGKYTT------NSSADHRVRLDLGLWDKFSELATKC 228

Query: 356 IQYVVEFAKRIDGFMELCQNDQIVLLKAGSLEVVFIRMCRAFDSQNNTVYF-DGKYASPD 414
           I  +VEFAKR+ GF  L   DQI LLKA  L+++ +R+C  +  + +T+ F DG   +  
Sbjct: 229 IIKIVEFAKRLPGFTGLTIADQITLLKAACLDILILRICTRYTPEQDTMTFSDGLTLNRT 288

Query: 415 VFKSLGCEDFISFVFEFGKSLCSMHLTEDEIALFSAFVLMSADRSWLQEKVKIEKLQQKI 474
              + G       VF F   L  + + + E  L SA  L+  DR  L+E  K++KLQ+ +
Sbjct: 289 QMHNAGFGPLTDLVFTFANQLLPLEMDDTETGLLSAICLICGDRQDLEEPTKVDKLQEPL 348

Query: 475 QLALQ-HVLQKNHREDGILTKLICKVSTLRALCGRHTEKLMAFKAIYPDIVRLHFPPLYK 533
             AL+ ++ ++   +  +  K++ K++ LR++  +  E+++  K   P       PPL +
Sbjct: 349 LEALKIYIRKRRPSKPHMFPKILMKITDLRSISAKGAERVITLKMEIPG----SMPPLIQ 404

Query: 534 EL 535
           E+
Sbjct: 405 EM 406


>gi|223718064 retinoic acid receptor, alpha isoform 1 [Homo sapiens]
          Length = 462

 Score =  120 bits (301), Expect = 3e-27
 Identities = 51/81 (62%), Positives = 63/81 (77%)

Query: 97  PCKICGDKSSGIHYGVITCEGCKGFFRRSQQSNATYSCPRQKNCLIDRTSRNRCQHCRLQ 156
           PC +C DKSSG HYGV  CEGCKGFFRRS Q N  Y+C R KNC+I++ +RNRCQ+CRLQ
Sbjct: 87  PCFVCQDKSSGYHYGVSACEGCKGFFRRSIQKNMVYTCHRDKNCIINKVTRNRCQYCRLQ 146

Query: 157 KCLAVGMSRDAVKFGRMSKKQ 177
           KC  VGMS+++V+  R  KK+
Sbjct: 147 KCFEVGMSKESVRNDRNKKKK 167



 Score = 89.4 bits (220), Expect = 8e-18
 Identities = 65/245 (26%), Positives = 117/245 (47%), Gaps = 20/245 (8%)

Query: 297 ELEHLAQNISKSHLETCQYLREELQQITWQTFLQEEIENYQNKQREVM----WQLCAIKI 352
           E+  L + + K+H ET   L +          L +   N  ++QR  +    W   +   
Sbjct: 183 EVGELIEKVRKAHQETFPALCQ----------LGKYTTNNSSEQRVSLDIDLWDKFSELS 232

Query: 353 TEAIQYVVEFAKRIDGFMELCQNDQIVLLKAGSLEVVFIRMCRAFDSQNNTVYF-DGKYA 411
           T+ I   VEFAK++ GF  L   DQI LLKA  L+++ +R+C  +  + +T+ F DG   
Sbjct: 233 TKCIIKTVEFAKQLPGFTTLTIADQITLLKAACLDILILRICTRYTPEQDTMTFSDGLTL 292

Query: 412 SPDVFKSLGCEDFISFVFEFGKSLCSMHLTEDEIALFSAFVLMSADRSWLQEKVKIEKLQ 471
           +     + G       VF F   L  + + + E  L SA  L+  DR  L++  +++ LQ
Sbjct: 293 NRTQMHNAGFGPLTDLVFAFANQLLPLEMDDAETGLLSAICLICGDRQDLEQPDRVDMLQ 352

Query: 472 QKIQLALQ-HVLQKNHREDGILTKLICKVSTLRALCGRHTEKLMAFKAIYPDIVRLHFPP 530
           + +  AL+ +V ++      +  K++ K++ LR++  +  E+++  K   P       PP
Sbjct: 353 EPLLEALKVYVRKRRPSRPHMFPKMLMKITDLRSISAKGAERVITLKMEIPG----SMPP 408

Query: 531 LYKEL 535
           L +E+
Sbjct: 409 LIQEM 413


>gi|67459914 retinoic acid receptor, alpha isoform 2 [Homo sapiens]
          Length = 457

 Score =  120 bits (301), Expect = 3e-27
 Identities = 51/81 (62%), Positives = 63/81 (77%)

Query: 97  PCKICGDKSSGIHYGVITCEGCKGFFRRSQQSNATYSCPRQKNCLIDRTSRNRCQHCRLQ 156
           PC +C DKSSG HYGV  CEGCKGFFRRS Q N  Y+C R KNC+I++ +RNRCQ+CRLQ
Sbjct: 82  PCFVCQDKSSGYHYGVSACEGCKGFFRRSIQKNMVYTCHRDKNCIINKVTRNRCQYCRLQ 141

Query: 157 KCLAVGMSRDAVKFGRMSKKQ 177
           KC  VGMS+++V+  R  KK+
Sbjct: 142 KCFEVGMSKESVRNDRNKKKK 162



 Score = 89.4 bits (220), Expect = 8e-18
 Identities = 65/245 (26%), Positives = 117/245 (47%), Gaps = 20/245 (8%)

Query: 297 ELEHLAQNISKSHLETCQYLREELQQITWQTFLQEEIENYQNKQREVM----WQLCAIKI 352
           E+  L + + K+H ET   L +          L +   N  ++QR  +    W   +   
Sbjct: 178 EVGELIEKVRKAHQETFPALCQ----------LGKYTTNNSSEQRVSLDIDLWDKFSELS 227

Query: 353 TEAIQYVVEFAKRIDGFMELCQNDQIVLLKAGSLEVVFIRMCRAFDSQNNTVYF-DGKYA 411
           T+ I   VEFAK++ GF  L   DQI LLKA  L+++ +R+C  +  + +T+ F DG   
Sbjct: 228 TKCIIKTVEFAKQLPGFTTLTIADQITLLKAACLDILILRICTRYTPEQDTMTFSDGLTL 287

Query: 412 SPDVFKSLGCEDFISFVFEFGKSLCSMHLTEDEIALFSAFVLMSADRSWLQEKVKIEKLQ 471
           +     + G       VF F   L  + + + E  L SA  L+  DR  L++  +++ LQ
Sbjct: 288 NRTQMHNAGFGPLTDLVFAFANQLLPLEMDDAETGLLSAICLICGDRQDLEQPDRVDMLQ 347

Query: 472 QKIQLALQ-HVLQKNHREDGILTKLICKVSTLRALCGRHTEKLMAFKAIYPDIVRLHFPP 530
           + +  AL+ +V ++      +  K++ K++ LR++  +  E+++  K   P       PP
Sbjct: 348 EPLLEALKVYVRKRRPSRPHMFPKMLMKITDLRSISAKGAERVITLKMEIPG----SMPP 403

Query: 531 LYKEL 535
           L +E+
Sbjct: 404 LIQEM 408


>gi|4506419 retinoic acid receptor, alpha isoform 1 [Homo sapiens]
          Length = 462

 Score =  120 bits (301), Expect = 3e-27
 Identities = 51/81 (62%), Positives = 63/81 (77%)

Query: 97  PCKICGDKSSGIHYGVITCEGCKGFFRRSQQSNATYSCPRQKNCLIDRTSRNRCQHCRLQ 156
           PC +C DKSSG HYGV  CEGCKGFFRRS Q N  Y+C R KNC+I++ +RNRCQ+CRLQ
Sbjct: 87  PCFVCQDKSSGYHYGVSACEGCKGFFRRSIQKNMVYTCHRDKNCIINKVTRNRCQYCRLQ 146

Query: 157 KCLAVGMSRDAVKFGRMSKKQ 177
           KC  VGMS+++V+  R  KK+
Sbjct: 147 KCFEVGMSKESVRNDRNKKKK 167



 Score = 89.4 bits (220), Expect = 8e-18
 Identities = 65/245 (26%), Positives = 117/245 (47%), Gaps = 20/245 (8%)

Query: 297 ELEHLAQNISKSHLETCQYLREELQQITWQTFLQEEIENYQNKQREVM----WQLCAIKI 352
           E+  L + + K+H ET   L +          L +   N  ++QR  +    W   +   
Sbjct: 183 EVGELIEKVRKAHQETFPALCQ----------LGKYTTNNSSEQRVSLDIDLWDKFSELS 232

Query: 353 TEAIQYVVEFAKRIDGFMELCQNDQIVLLKAGSLEVVFIRMCRAFDSQNNTVYF-DGKYA 411
           T+ I   VEFAK++ GF  L   DQI LLKA  L+++ +R+C  +  + +T+ F DG   
Sbjct: 233 TKCIIKTVEFAKQLPGFTTLTIADQITLLKAACLDILILRICTRYTPEQDTMTFSDGLTL 292

Query: 412 SPDVFKSLGCEDFISFVFEFGKSLCSMHLTEDEIALFSAFVLMSADRSWLQEKVKIEKLQ 471
           +     + G       VF F   L  + + + E  L SA  L+  DR  L++  +++ LQ
Sbjct: 293 NRTQMHNAGFGPLTDLVFAFANQLLPLEMDDAETGLLSAICLICGDRQDLEQPDRVDMLQ 352

Query: 472 QKIQLALQ-HVLQKNHREDGILTKLICKVSTLRALCGRHTEKLMAFKAIYPDIVRLHFPP 530
           + +  AL+ +V ++      +  K++ K++ LR++  +  E+++  K   P       PP
Sbjct: 353 EPLLEALKVYVRKRRPSRPHMFPKMLMKITDLRSISAKGAERVITLKMEIPG----SMPP 408

Query: 531 LYKEL 535
           L +E+
Sbjct: 409 LIQEM 413


>gi|4506755 retinoid X receptor, alpha [Homo sapiens]
          Length = 462

 Score =  115 bits (289), Expect = 8e-26
 Identities = 58/127 (45%), Positives = 79/127 (62%), Gaps = 16/127 (12%)

Query: 98  CKICGDKSSGIHYGVITCEGCKGFFRRSQQSNATYSCPRQKNCLIDRTSRNRCQHCRLQK 157
           C ICGD+SSG HYGV +CEGCKGFF+R+ + + TY+C   K+CLID+  RNRCQ+CR QK
Sbjct: 135 CAICGDRSSGKHYGVYSCEGCKGFFKRTVRKDLTYTCRDNKDCLIDKRQRNRCQYCRYQK 194

Query: 158 CLAVGMSRDAVKFGRMSKKQRDSLYAEVQKHRMQQQQRDHQQQPGE--------AEPLTP 209
           CLA+GM R+AV+  R   K R+       ++ ++     ++  P E         EP T 
Sbjct: 195 CLAMGMKREAVQEERQRGKDRN-------ENEVESTSSANEDMPVERILEAELAVEPKTE 247

Query: 210 TYNISAN 216
           TY + AN
Sbjct: 248 TY-VEAN 253



 Score = 57.0 bits (136), Expect = 4e-08
 Identities = 44/164 (26%), Positives = 78/164 (47%), Gaps = 3/164 (1%)

Query: 359 VVEFAKRIDGFMELCQNDQIVLLKAGSLEVVFIRMC-RAFDSQNNTVYFDGKYASPDVFK 417
           +VE+AKRI  F EL  +DQ++LL+AG  E++      R+   ++  +   G +   +   
Sbjct: 279 LVEWAKRIPHFSELPLDDQVILLRAGWNELLIASFSHRSIAVKDGILLATGLHVHRNSAH 338

Query: 418 SLGCEDFISFVF-EFGKSLCSMHLTEDEIALFSAFVLMSADRSWLQEKVKIEKLQQKIQL 476
           S G       V  E    +  M + + E+    A VL + D   L    ++E L++K+  
Sbjct: 339 SAGVGAIFDRVLTELVSKMRDMQMDKTELGCLRAIVLFNPDSKGLSNPAEVEALREKVYA 398

Query: 477 ALQ-HVLQKNHREDGILTKLICKVSTLRALCGRHTEKLMAFKAI 519
           +L+ +   K   + G   KL+ ++  LR++  +  E L  FK I
Sbjct: 399 SLEAYCKHKYPEQPGRFAKLLLRLPALRSIGLKCLEHLFFFKLI 442


>gi|189491766 nuclear receptor subfamily 2, group C, member 1
           isoform c [Homo sapiens]
          Length = 483

 Score =  114 bits (286), Expect = 2e-25
 Identities = 62/152 (40%), Positives = 94/152 (61%), Gaps = 15/152 (9%)

Query: 98  CKICGDKSSGIHYGVITCEGCKGFFRRSQQSNATYSCPRQKNCLIDRTSRNRCQHCRLQK 157
           C +CGDK+SG HYG +TCEGCKGFF+RS + N  YSC   K+C+I++  RNRCQ+CRLQ+
Sbjct: 113 CVVCGDKASGRHYGAVTCEGCKGFFKRSIRKNLVYSCRGSKDCIINKHHRNRCQYCRLQR 172

Query: 158 CLAVGMSRDAVKFGR----MSKKQRDSLYAEVQKHRMQQQQRDHQQQPGEAEP--LTPTY 211
           C+A GM +D+V+  R    +S+++  +  A  +K  +++  R     P  A P  +T + 
Sbjct: 173 CIAFGMKQDSVQCERKPIEVSREKSSNCAASTEKIYIRKDLR----SPLTATPTFVTDSE 228

Query: 212 NISANGLTELHDDLSNYIDGHTPEGSKADSAV 243
           +  + GL     D   +++ H P G K +SAV
Sbjct: 229 STRSTGLL----DSGMFMNIH-PSGVKTESAV 255


>gi|73808084 nuclear receptor subfamily 2, group C, member 1 isoform
           b [Homo sapiens]
          Length = 467

 Score =  114 bits (286), Expect = 2e-25
 Identities = 62/152 (40%), Positives = 94/152 (61%), Gaps = 15/152 (9%)

Query: 98  CKICGDKSSGIHYGVITCEGCKGFFRRSQQSNATYSCPRQKNCLIDRTSRNRCQHCRLQK 157
           C +CGDK+SG HYG +TCEGCKGFF+RS + N  YSC   K+C+I++  RNRCQ+CRLQ+
Sbjct: 113 CVVCGDKASGRHYGAVTCEGCKGFFKRSIRKNLVYSCRGSKDCIINKHHRNRCQYCRLQR 172

Query: 158 CLAVGMSRDAVKFGR----MSKKQRDSLYAEVQKHRMQQQQRDHQQQPGEAEP--LTPTY 211
           C+A GM +D+V+  R    +S+++  +  A  +K  +++  R     P  A P  +T + 
Sbjct: 173 CIAFGMKQDSVQCERKPIEVSREKSSNCAASTEKIYIRKDLR----SPLTATPTFVTDSE 228

Query: 212 NISANGLTELHDDLSNYIDGHTPEGSKADSAV 243
           +  + GL     D   +++ H P G K +SAV
Sbjct: 229 STRSTGLL----DSGMFMNIH-PSGVKTESAV 255


>gi|116284373 peroxisome proliferative activated receptor gamma
           isoform 1 [Homo sapiens]
          Length = 477

 Score =  114 bits (284), Expect = 3e-25
 Identities = 51/91 (56%), Positives = 67/91 (73%), Gaps = 3/91 (3%)

Query: 96  IPCKICGDKSSGIHYGVITCEGCKGFFRRSQQSNATYS-CPRQKNCLIDRTSRNRCQHCR 154
           I C++CGDK+SG HYGV  CEGCKGFFRR+ +    Y  C    NC I + SRN+CQ+CR
Sbjct: 109 IECRVCGDKASGFHYGVHACEGCKGFFRRTIRLKLIYDRC--DLNCRIHKKSRNKCQYCR 166

Query: 155 LQKCLAVGMSRDAVKFGRMSKKQRDSLYAEV 185
            QKCLAVGMS +A++FGRM + +++ L AE+
Sbjct: 167 FQKCLAVGMSHNAIRFGRMPQAEKEKLLAEI 197



 Score = 92.8 bits (229), Expect = 7e-19
 Identities = 63/212 (29%), Positives = 107/212 (50%), Gaps = 9/212 (4%)

Query: 331 EEIENYQNKQREV---MWQLCAIKITEAIQYVVEFAKRIDGFMELCQNDQIVLLKAGSLE 387
           + I   Q + +EV   ++Q C  +  EA+Q + E+AK I GF+ L  NDQ+ LLK G  E
Sbjct: 265 KHITPLQEQSKEVAIRIFQGCQFRSVEAVQEITEYAKSIPGFVNLDLNDQVTLLKYGVHE 324

Query: 388 VVFIRMCRAFDSQNNTVYFDGKYASPDVFKSL--GCEDFISFVFEFGKSLCSMHLTEDEI 445
           +++  +    +     +     + + +  KSL     DF+   FEF     ++ L + ++
Sbjct: 325 IIYTMLASLMNKDGVLISEGQGFMTREFLKSLRKPFGDFMEPKFEFAVKFNALELDDSDL 384

Query: 446 ALFSAFVLMSADRSWLQEKVKIEKLQQKIQLALQHVLQKNHREDG-ILTKLICKVSTLRA 504
           A+F A +++S DR  L     IE +Q  +  AL+  L+ NH E   +  KL+ K++ LR 
Sbjct: 385 AIFIAVIILSGDRPGLLNVKPIEDIQDNLLQALELQLKLNHPESSQLFAKLLQKMTDLRQ 444

Query: 505 LCGRHTEKLMAFKAIYPDIVRLHFPPLYKELF 536
           +   H + L   K    D + LH  PL +E++
Sbjct: 445 IVTEHVQLLQVIKKTETD-MSLH--PLLQEIY 473


>gi|20336229 peroxisome proliferative activated receptor gamma
           isoform 2 [Homo sapiens]
          Length = 505

 Score =  114 bits (284), Expect = 3e-25
 Identities = 51/91 (56%), Positives = 67/91 (73%), Gaps = 3/91 (3%)

Query: 96  IPCKICGDKSSGIHYGVITCEGCKGFFRRSQQSNATYS-CPRQKNCLIDRTSRNRCQHCR 154
           I C++CGDK+SG HYGV  CEGCKGFFRR+ +    Y  C    NC I + SRN+CQ+CR
Sbjct: 137 IECRVCGDKASGFHYGVHACEGCKGFFRRTIRLKLIYDRC--DLNCRIHKKSRNKCQYCR 194

Query: 155 LQKCLAVGMSRDAVKFGRMSKKQRDSLYAEV 185
            QKCLAVGMS +A++FGRM + +++ L AE+
Sbjct: 195 FQKCLAVGMSHNAIRFGRMPQAEKEKLLAEI 225



 Score = 92.8 bits (229), Expect = 7e-19
 Identities = 63/212 (29%), Positives = 107/212 (50%), Gaps = 9/212 (4%)

Query: 331 EEIENYQNKQREV---MWQLCAIKITEAIQYVVEFAKRIDGFMELCQNDQIVLLKAGSLE 387
           + I   Q + +EV   ++Q C  +  EA+Q + E+AK I GF+ L  NDQ+ LLK G  E
Sbjct: 293 KHITPLQEQSKEVAIRIFQGCQFRSVEAVQEITEYAKSIPGFVNLDLNDQVTLLKYGVHE 352

Query: 388 VVFIRMCRAFDSQNNTVYFDGKYASPDVFKSL--GCEDFISFVFEFGKSLCSMHLTEDEI 445
           +++  +    +     +     + + +  KSL     DF+   FEF     ++ L + ++
Sbjct: 353 IIYTMLASLMNKDGVLISEGQGFMTREFLKSLRKPFGDFMEPKFEFAVKFNALELDDSDL 412

Query: 446 ALFSAFVLMSADRSWLQEKVKIEKLQQKIQLALQHVLQKNHREDG-ILTKLICKVSTLRA 504
           A+F A +++S DR  L     IE +Q  +  AL+  L+ NH E   +  KL+ K++ LR 
Sbjct: 413 AIFIAVIILSGDRPGLLNVKPIEDIQDNLLQALELQLKLNHPESSQLFAKLLQKMTDLRQ 472

Query: 505 LCGRHTEKLMAFKAIYPDIVRLHFPPLYKELF 536
           +   H + L   K    D + LH  PL +E++
Sbjct: 473 IVTEHVQLLQVIKKTETD-MSLH--PLLQEIY 501


>gi|116284368 peroxisome proliferative activated receptor gamma
           isoform 1 [Homo sapiens]
          Length = 477

 Score =  114 bits (284), Expect = 3e-25
 Identities = 51/91 (56%), Positives = 67/91 (73%), Gaps = 3/91 (3%)

Query: 96  IPCKICGDKSSGIHYGVITCEGCKGFFRRSQQSNATYS-CPRQKNCLIDRTSRNRCQHCR 154
           I C++CGDK+SG HYGV  CEGCKGFFRR+ +    Y  C    NC I + SRN+CQ+CR
Sbjct: 109 IECRVCGDKASGFHYGVHACEGCKGFFRRTIRLKLIYDRC--DLNCRIHKKSRNKCQYCR 166

Query: 155 LQKCLAVGMSRDAVKFGRMSKKQRDSLYAEV 185
            QKCLAVGMS +A++FGRM + +++ L AE+
Sbjct: 167 FQKCLAVGMSHNAIRFGRMPQAEKEKLLAEI 197



 Score = 92.8 bits (229), Expect = 7e-19
 Identities = 63/212 (29%), Positives = 107/212 (50%), Gaps = 9/212 (4%)

Query: 331 EEIENYQNKQREV---MWQLCAIKITEAIQYVVEFAKRIDGFMELCQNDQIVLLKAGSLE 387
           + I   Q + +EV   ++Q C  +  EA+Q + E+AK I GF+ L  NDQ+ LLK G  E
Sbjct: 265 KHITPLQEQSKEVAIRIFQGCQFRSVEAVQEITEYAKSIPGFVNLDLNDQVTLLKYGVHE 324

Query: 388 VVFIRMCRAFDSQNNTVYFDGKYASPDVFKSL--GCEDFISFVFEFGKSLCSMHLTEDEI 445
           +++  +    +     +     + + +  KSL     DF+   FEF     ++ L + ++
Sbjct: 325 IIYTMLASLMNKDGVLISEGQGFMTREFLKSLRKPFGDFMEPKFEFAVKFNALELDDSDL 384

Query: 446 ALFSAFVLMSADRSWLQEKVKIEKLQQKIQLALQHVLQKNHREDG-ILTKLICKVSTLRA 504
           A+F A +++S DR  L     IE +Q  +  AL+  L+ NH E   +  KL+ K++ LR 
Sbjct: 385 AIFIAVIILSGDRPGLLNVKPIEDIQDNLLQALELQLKLNHPESSQLFAKLLQKMTDLRQ 444

Query: 505 LCGRHTEKLMAFKAIYPDIVRLHFPPLYKELF 536
           +   H + L   K    D + LH  PL +E++
Sbjct: 445 IVTEHVQLLQVIKKTETD-MSLH--PLLQEIY 473


>gi|116284370 peroxisome proliferative activated receptor gamma
           isoform 1 [Homo sapiens]
          Length = 477

 Score =  114 bits (284), Expect = 3e-25
 Identities = 51/91 (56%), Positives = 67/91 (73%), Gaps = 3/91 (3%)

Query: 96  IPCKICGDKSSGIHYGVITCEGCKGFFRRSQQSNATYS-CPRQKNCLIDRTSRNRCQHCR 154
           I C++CGDK+SG HYGV  CEGCKGFFRR+ +    Y  C    NC I + SRN+CQ+CR
Sbjct: 109 IECRVCGDKASGFHYGVHACEGCKGFFRRTIRLKLIYDRC--DLNCRIHKKSRNKCQYCR 166

Query: 155 LQKCLAVGMSRDAVKFGRMSKKQRDSLYAEV 185
            QKCLAVGMS +A++FGRM + +++ L AE+
Sbjct: 167 FQKCLAVGMSHNAIRFGRMPQAEKEKLLAEI 197



 Score = 92.8 bits (229), Expect = 7e-19
 Identities = 63/212 (29%), Positives = 107/212 (50%), Gaps = 9/212 (4%)

Query: 331 EEIENYQNKQREV---MWQLCAIKITEAIQYVVEFAKRIDGFMELCQNDQIVLLKAGSLE 387
           + I   Q + +EV   ++Q C  +  EA+Q + E+AK I GF+ L  NDQ+ LLK G  E
Sbjct: 265 KHITPLQEQSKEVAIRIFQGCQFRSVEAVQEITEYAKSIPGFVNLDLNDQVTLLKYGVHE 324

Query: 388 VVFIRMCRAFDSQNNTVYFDGKYASPDVFKSL--GCEDFISFVFEFGKSLCSMHLTEDEI 445
           +++  +    +     +     + + +  KSL     DF+   FEF     ++ L + ++
Sbjct: 325 IIYTMLASLMNKDGVLISEGQGFMTREFLKSLRKPFGDFMEPKFEFAVKFNALELDDSDL 384

Query: 446 ALFSAFVLMSADRSWLQEKVKIEKLQQKIQLALQHVLQKNHREDG-ILTKLICKVSTLRA 504
           A+F A +++S DR  L     IE +Q  +  AL+  L+ NH E   +  KL+ K++ LR 
Sbjct: 385 AIFIAVIILSGDRPGLLNVKPIEDIQDNLLQALELQLKLNHPESSQLFAKLLQKMTDLRQ 444

Query: 505 LCGRHTEKLMAFKAIYPDIVRLHFPPLYKELF 536
           +   H + L   K    D + LH  PL +E++
Sbjct: 445 IVTEHVQLLQVIKKTETD-MSLH--PLLQEIY 473


>gi|5032173 nuclear receptor subfamily 2, group F, member 1 [Homo
           sapiens]
          Length = 423

 Score =  114 bits (284), Expect = 3e-25
 Identities = 50/82 (60%), Positives = 61/82 (74%)

Query: 96  IPCKICGDKSSGIHYGVITCEGCKGFFRRSQQSNATYSCPRQKNCLIDRTSRNRCQHCRL 155
           I C +CGDKSSG HYG  TCEGCK FF+RS + N TY+C   +NC ID+  RN+CQ+CRL
Sbjct: 84  IECVVCGDKSSGKHYGQFTCEGCKSFFKRSVRRNLTYTCRANRNCPIDQHHRNQCQYCRL 143

Query: 156 QKCLAVGMSRDAVKFGRMSKKQ 177
           +KCL VGM R+AV+ GRM   Q
Sbjct: 144 KKCLKVGMRREAVQRGRMPPTQ 165



 Score = 46.2 bits (108), Expect = 8e-05
 Identities = 42/164 (25%), Positives = 74/164 (45%), Gaps = 4/164 (2%)

Query: 360 VEFAKRIDGFMELCQNDQIVLLKA--GSLEVVFIRMCRAFDSQNNTVYFDGKYASP-DVF 416
           VE+A+ I  F +L   DQ+ LL+     L V+    C         +   G +ASP    
Sbjct: 231 VEWARNIPFFPDLQITDQVSLLRLTWSELFVLNAAQCSMPLHVAPLLAAAGLHASPMSAD 290

Query: 417 KSLGCEDFISFVFEFGKSLCSMHLTEDEIALFSAFVLMSADRSWLQEKVKIEKLQQKIQL 476
           + +   D I    E  + L ++H+   E +   A VL ++D   L +   IE LQ+K Q 
Sbjct: 291 RVVAFMDHIRIFQEQVEKLKALHVDSAEYSCLKAIVLFTSDACGLSDAAHIESLQEKSQC 350

Query: 477 ALQHVLQKNH-REDGILTKLICKVSTLRALCGRHTEKLMAFKAI 519
           AL+  ++  +  +     KL+ ++ +LR +     E+L   + +
Sbjct: 351 ALEEYVRSQYPNQPSRFGKLLLRLPSLRTVSSSVIEQLFFVRLV 394


>gi|14149746 nuclear receptor subfamily 2, group F, member 2 isoform
           a [Homo sapiens]
          Length = 414

 Score =  113 bits (283), Expect = 4e-25
 Identities = 50/89 (56%), Positives = 65/89 (73%)

Query: 89  RKAQIEIIPCKICGDKSSGIHYGVITCEGCKGFFRRSQQSNATYSCPRQKNCLIDRTSRN 148
           ++ Q + I C +CGDKSSG HYG  TCEGCK FF+RS + N +Y+C   +NC ID+  RN
Sbjct: 70  KQQQQQHIECVVCGDKSSGKHYGQFTCEGCKSFFKRSVRRNLSYTCRANRNCPIDQHHRN 129

Query: 149 RCQHCRLQKCLAVGMSRDAVKFGRMSKKQ 177
           +CQ+CRL+KCL VGM R+AV+ GRM   Q
Sbjct: 130 QCQYCRLKKCLKVGMRREAVQRGRMPPTQ 158



 Score = 45.4 bits (106), Expect = 1e-04
 Identities = 41/164 (25%), Positives = 74/164 (45%), Gaps = 4/164 (2%)

Query: 360 VEFAKRIDGFMELCQNDQIVLLKA--GSLEVVFIRMCRAFDSQNNTVYFDGKYASP-DVF 416
           VE+A+ I  F +L   DQ+ LL+     L V+    C         +   G +ASP    
Sbjct: 224 VEWARNIPFFPDLQITDQVALLRLTWSELFVLNAAQCSMPLHVAPLLAAAGLHASPMSAD 283

Query: 417 KSLGCEDFISFVFEFGKSLCSMHLTEDEIALFSAFVLMSADRSWLQEKVKIEKLQQKIQL 476
           + +   D I    E  + L ++H+   E +   A VL ++D   L +   +E LQ+K Q 
Sbjct: 284 RVVAFMDHIRIFQEQVEKLKALHVDSAEYSCLKAIVLFTSDACGLSDVAHVESLQEKSQC 343

Query: 477 ALQHVLQKNH-REDGILTKLICKVSTLRALCGRHTEKLMAFKAI 519
           AL+  ++  +  +     KL+ ++ +LR +     E+L   + +
Sbjct: 344 ALEEYVRSQYPNQPTRFGKLLLRLPSLRTVSSSVIEQLFFVRLV 387


>gi|11415052 retinoid X receptor, beta [Homo sapiens]
          Length = 533

 Score =  113 bits (283), Expect = 4e-25
 Identities = 48/82 (58%), Positives = 61/82 (74%)

Query: 98  CKICGDKSSGIHYGVITCEGCKGFFRRSQQSNATYSCPRQKNCLIDRTSRNRCQHCRLQK 157
           C ICGD+SSG HYGV +CEGCKGFF+R+ + + TYSC   K+C +D+  RNRCQ+CR QK
Sbjct: 205 CAICGDRSSGKHYGVYSCEGCKGFFKRTIRKDLTYSCRDNKDCTVDKRQRNRCQYCRYQK 264

Query: 158 CLAVGMSRDAVKFGRMSKKQRD 179
           CLA GM R+AV+  R   K +D
Sbjct: 265 CLATGMKREAVQEERQRGKDKD 286



 Score = 58.9 bits (141), Expect = 1e-08
 Identities = 44/164 (26%), Positives = 79/164 (48%), Gaps = 3/164 (1%)

Query: 359 VVEFAKRIDGFMELCQNDQIVLLKAGSLEVVFIRMC-RAFDSQNNTVYFDGKYASPDVFK 417
           +VE+AKRI  F  L  +DQ++LL+AG  E++      R+ D ++  +   G +   +   
Sbjct: 350 LVEWAKRIPHFSSLPLDDQVILLRAGWNELLIASFSHRSIDVRDGILLATGLHVHRNSAH 409

Query: 418 SLGCEDFISFVF-EFGKSLCSMHLTEDEIALFSAFVLMSADRSWLQEKVKIEKLQQKIQL 476
           S G       V  E    +  M + + E+    A +L + D   L    ++E L++K+  
Sbjct: 410 SAGVGAIFDRVLTELVSKMRDMRMDKTELGCLRAIILFNPDAKGLSNPSEVEVLREKVYA 469

Query: 477 ALQ-HVLQKNHREDGILTKLICKVSTLRALCGRHTEKLMAFKAI 519
           +L+ +  QK   + G   KL+ ++  LR++  +  E L  FK I
Sbjct: 470 SLETYCKQKYPEQQGRFAKLLLRLPALRSIGLKCLEHLFFFKLI 513


>gi|5902068 retinoid X receptor, gamma isoform a [Homo sapiens]
          Length = 463

 Score =  111 bits (278), Expect = 1e-24
 Identities = 48/87 (55%), Positives = 63/87 (72%)

Query: 98  CKICGDKSSGIHYGVITCEGCKGFFRRSQQSNATYSCPRQKNCLIDRTSRNRCQHCRLQK 157
           C ICGD+SSG HYGV +CEGCKGFF+R+ + +  Y+C   K+CLID+  RNRCQ+CR QK
Sbjct: 139 CAICGDRSSGKHYGVYSCEGCKGFFKRTIRKDLIYTCRDNKDCLIDKRQRNRCQYCRYQK 198

Query: 158 CLAVGMSRDAVKFGRMSKKQRDSLYAE 184
           CL +GM R+AV+  R   ++R    AE
Sbjct: 199 CLVMGMKREAVQEERQRSRERAESEAE 225



 Score = 60.8 bits (146), Expect = 3e-09
 Identities = 48/188 (25%), Positives = 84/188 (44%), Gaps = 4/188 (2%)

Query: 335 NYQNKQREVMWQLCAIKITEAIQYVVEFAKRIDGFMELCQNDQIVLLKAGSLEVVFIRMC 394
           N +N   + +  +C     +    +VE+AKRI  F +L   DQ++LL+AG  E++     
Sbjct: 257 NMENSTNDPVTNICHAADKQLFT-LVEWAKRIPHFSDLTLEDQVILLRAGWNELLIASFS 315

Query: 395 -RAFDSQNNTVYFDGKYASPDVFKSLGCEDFISFVF-EFGKSLCSMHLTEDEIALFSAFV 452
            R+   Q+  +   G +       S G       V  E    +  M + + E+    A V
Sbjct: 316 HRSVSVQDGILLATGLHVHRSSAHSAGVGSIFDRVLTELVSKMKDMQMDKSELGCLRAIV 375

Query: 453 LMSADRSWLQEKVKIEKLQQKIQLALQ-HVLQKNHREDGILTKLICKVSTLRALCGRHTE 511
           L + D   L    ++E L++K+   L+ +  QK   + G   KL+ ++  LR++  +  E
Sbjct: 376 LFNPDAKGLSNPSEVETLREKVYATLEAYTKQKYPEQPGRFAKLLLRLPALRSIGLKCLE 435

Query: 512 KLMAFKAI 519
            L  FK I
Sbjct: 436 HLFFFKLI 443


  Database: hs.faa
    Posted date:  Aug 4, 2009  4:42 PM
  Number of letters in database: 18,247,518
  Number of sequences in database:  37,866
  
Lambda     K      H
   0.321    0.134    0.408 

Gapped
Lambda     K      H
   0.267   0.0410    0.140 


Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Hits to DB: 21,802,757
Number of Sequences: 37866
Number of extensions: 995390
Number of successful extensions: 4379
Number of sequences better than 10.0: 30
Number of HSP's better than 10.0 without gapping: 125
Number of HSP's successfully gapped in prelim test: 12
Number of HSP's that attempted gapping in prelim test: 3952
Number of HSP's gapped (non-prelim): 312
length of query: 548
length of database: 18,247,518
effective HSP length: 107
effective length of query: 441
effective length of database: 14,195,856
effective search space: 6260372496
effective search space used: 6260372496
T: 11
A: 40
X1: 16 ( 7.4 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 41 (21.9 bits)
S2: 64 (29.3 bits)

Search results were obtained with NCBI BLAST and RefSeq entries.


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Guide to the Human Genome
Copyright © 2010 by Stewart Scherer. All rights reserved.

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