BLASTP 2.2.11 [Jun-05-2005] Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer, Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), "Gapped BLAST and PSI-BLAST: a new generation of protein database search programs", Nucleic Acids Res. 25:3389-3402. Query= gi|4506189 proteasome alpha 7 subunit [Homo sapiens] (248 letters) Database: hs.faa 37,866 sequences; 18,247,518 total letters Searching..................................................done Score E Sequences producing significant alignments: (bits) Value gi|4506189 proteasome alpha 7 subunit [Homo sapiens] 486 e-137 gi|68303563 proteasome alpha 8 subunit isoform 2 [Homo sapiens] 416 e-116 gi|68303561 proteasome alpha 8 subunit isoform 1 [Homo sapiens] 409 e-114 gi|68303565 proteasome alpha 8 subunit isoform 3 [Homo sapiens] 330 9e-91 gi|156713442 proteasome alpha 4 subunit isoform 1 [Homo sapiens] 162 3e-40 gi|4506185 proteasome alpha 4 subunit isoform 1 [Homo sapiens] 162 3e-40 gi|4506181 proteasome subunit alpha type 2 [Homo sapiens] 160 1e-39 gi|23110942 proteasome alpha 5 subunit [Homo sapiens] 152 3e-37 gi|4506179 proteasome alpha 1 subunit isoform 2 [Homo sapiens] 138 5e-33 gi|23110935 proteasome alpha 1 subunit isoform 1 [Homo sapiens] 138 5e-33 gi|23110944 proteasome alpha 6 subunit [Homo sapiens] 132 2e-31 gi|4506183 proteasome alpha 3 subunit isoform 1 [Homo sapiens] 125 3e-29 gi|23110939 proteasome alpha 3 subunit isoform 2 [Homo sapiens] 119 3e-27 gi|156713444 proteasome alpha 4 subunit isoform 2 [Homo sapiens] 111 7e-25 gi|221316716 proteasome alpha 1 subunit isoform 3 [Homo sapiens] 82 4e-16 gi|4506191 proteasome beta 10 subunit proprotein [Homo sapiens] 55 6e-08 gi|169206322 PREDICTED: similar to hCG30646 [Homo sapiens] 54 1e-07 gi|239750562 PREDICTED: similar to hCG30646 [Homo sapiens] 54 1e-07 gi|239744861 PREDICTED: similar to hCG30646 [Homo sapiens] 54 1e-07 gi|4506201 proteasome beta 5 subunit isoform 1 [Homo sapiens] 43 3e-04 gi|4506203 proteasome beta 7 subunit proprotein [Homo sapiens] 42 4e-04 gi|23110932 proteasome beta 9 subunit isoform 2 proprotein [Homo... 38 0.007 gi|4506205 proteasome beta 9 subunit isoform 1 proprotein [Homo ... 38 0.007 gi|239787084 zinc finger protein 611 isoform a [Homo sapiens] 32 0.51 gi|239787082 zinc finger protein 611 isoform a [Homo sapiens] 32 0.51 gi|239787080 zinc finger protein 611 isoform a [Homo sapiens] 32 0.51 gi|16507237 heat shock 70kDa protein 5 [Homo sapiens] 32 0.51 gi|51988900 XPG-complementing protein [Homo sapiens] 32 0.51 gi|21361831 partitioning-defective protein 3 homolog [Homo sapiens] 32 0.51 gi|4506193 proteasome beta 1 subunit [Homo sapiens] 31 0.88 >gi|4506189 proteasome alpha 7 subunit [Homo sapiens] Length = 248 Score = 486 bits (1250), Expect = e-137 Identities = 248/248 (100%), Positives = 248/248 (100%) Query: 1 MSYDRAITVFSPDGHLFQVEYAQEAVKKGSTAVGVRGRDIVVLGVEKKSVAKLQDERTVR 60 MSYDRAITVFSPDGHLFQVEYAQEAVKKGSTAVGVRGRDIVVLGVEKKSVAKLQDERTVR Sbjct: 1 MSYDRAITVFSPDGHLFQVEYAQEAVKKGSTAVGVRGRDIVVLGVEKKSVAKLQDERTVR 60 Query: 61 KICALDDNVCMAFAGLTADARIVINRARVECQSHRLTVEDPVTVEYITRYIASLKQRYTQ 120 KICALDDNVCMAFAGLTADARIVINRARVECQSHRLTVEDPVTVEYITRYIASLKQRYTQ Sbjct: 61 KICALDDNVCMAFAGLTADARIVINRARVECQSHRLTVEDPVTVEYITRYIASLKQRYTQ 120 Query: 121 SNGRRPFGISALIVGFDFDGTPRLYQTDPSGTYHAWKANAIGRGAKSVREFLEKNYTDEA 180 SNGRRPFGISALIVGFDFDGTPRLYQTDPSGTYHAWKANAIGRGAKSVREFLEKNYTDEA Sbjct: 121 SNGRRPFGISALIVGFDFDGTPRLYQTDPSGTYHAWKANAIGRGAKSVREFLEKNYTDEA 180 Query: 181 IETDDLTIKLVIKALLEVVQSGGKNIELAVMRRDQSLKILNPEEIEKYVAEIEKEKEENE 240 IETDDLTIKLVIKALLEVVQSGGKNIELAVMRRDQSLKILNPEEIEKYVAEIEKEKEENE Sbjct: 181 IETDDLTIKLVIKALLEVVQSGGKNIELAVMRRDQSLKILNPEEIEKYVAEIEKEKEENE 240 Query: 241 KKKQKKAS 248 KKKQKKAS Sbjct: 241 KKKQKKAS 248 >gi|68303563 proteasome alpha 8 subunit isoform 2 [Homo sapiens] Length = 250 Score = 416 bits (1068), Expect = e-116 Identities = 208/245 (84%), Positives = 228/245 (93%) Query: 3 YDRAITVFSPDGHLFQVEYAQEAVKKGSTAVGVRGRDIVVLGVEKKSVAKLQDERTVRKI 62 YDRAITVFSPDGHLFQVEYAQEAVKKGSTAVG+RG +IVVLGVEKKSVAKLQDERTVRKI Sbjct: 5 YDRAITVFSPDGHLFQVEYAQEAVKKGSTAVGIRGTNIVVLGVEKKSVAKLQDERTVRKI 64 Query: 63 CALDDNVCMAFAGLTADARIVINRARVECQSHRLTVEDPVTVEYITRYIASLKQRYTQSN 122 CALDD+VCMAFAGLTADAR+VINRARVECQSH+LTVEDPVTVEYITR+IA+LKQ+YTQSN Sbjct: 65 CALDDHVCMAFAGLTADARVVINRARVECQSHKLTVEDPVTVEYITRFIATLKQKYTQSN 124 Query: 123 GRRPFGISALIVGFDFDGTPRLYQTDPSGTYHAWKANAIGRGAKSVREFLEKNYTDEAIE 182 GRRPFGISALIVGFD DG RLYQTDPSGTYHAWKANAIGR AK+VREFLEKNYT++AI Sbjct: 125 GRRPFGISALIVGFDDDGISRLYQTDPSGTYHAWKANAIGRSAKTVREFLEKNYTEDAIA 184 Query: 183 TDDLTIKLVIKALLEVVQSGGKNIELAVMRRDQSLKILNPEEIEKYVAEIEKEKEENEKK 242 +D IKL IKALLEVVQSGGKNIELA++RR+Q LK+ + +E+E YV EIEKEKEE EKK Sbjct: 185 SDSEAIKLAIKALLEVVQSGGKNIELAIIRRNQPLKMFSAKEVELYVTEIEKEKEEAEKK 244 Query: 243 KQKKA 247 K KK+ Sbjct: 245 KSKKS 249 >gi|68303561 proteasome alpha 8 subunit isoform 1 [Homo sapiens] Length = 256 Score = 409 bits (1051), Expect = e-114 Identities = 208/251 (82%), Positives = 228/251 (90%), Gaps = 6/251 (2%) Query: 3 YDRAITVFSPDGHLFQVEYAQEAVKKGSTAVGVRGRDIVVLGVEKKSVAKLQDERTVRKI 62 YDRAITVFSPDGHLFQVEYAQEAVKKGSTAVG+RG +IVVLGVEKKSVAKLQDERTVRKI Sbjct: 5 YDRAITVFSPDGHLFQVEYAQEAVKKGSTAVGIRGTNIVVLGVEKKSVAKLQDERTVRKI 64 Query: 63 CALDDNVCMAFA------GLTADARIVINRARVECQSHRLTVEDPVTVEYITRYIASLKQ 116 CALDD+VCMAFA GLTADAR+VINRARVECQSH+LTVEDPVTVEYITR+IA+LKQ Sbjct: 65 CALDDHVCMAFAVLTIFIGLTADARVVINRARVECQSHKLTVEDPVTVEYITRFIATLKQ 124 Query: 117 RYTQSNGRRPFGISALIVGFDFDGTPRLYQTDPSGTYHAWKANAIGRGAKSVREFLEKNY 176 +YTQSNGRRPFGISALIVGFD DG RLYQTDPSGTYHAWKANAIGR AK+VREFLEKNY Sbjct: 125 KYTQSNGRRPFGISALIVGFDDDGISRLYQTDPSGTYHAWKANAIGRSAKTVREFLEKNY 184 Query: 177 TDEAIETDDLTIKLVIKALLEVVQSGGKNIELAVMRRDQSLKILNPEEIEKYVAEIEKEK 236 T++AI +D IKL IKALLEVVQSGGKNIELA++RR+Q LK+ + +E+E YV EIEKEK Sbjct: 185 TEDAIASDSEAIKLAIKALLEVVQSGGKNIELAIIRRNQPLKMFSAKEVELYVTEIEKEK 244 Query: 237 EENEKKKQKKA 247 EE EKKK KK+ Sbjct: 245 EEAEKKKSKKS 255 >gi|68303565 proteasome alpha 8 subunit isoform 3 [Homo sapiens] Length = 212 Score = 330 bits (845), Expect = 9e-91 Identities = 173/245 (70%), Positives = 191/245 (77%), Gaps = 38/245 (15%) Query: 3 YDRAITVFSPDGHLFQVEYAQEAVKKGSTAVGVRGRDIVVLGVEKKSVAKLQDERTVRKI 62 YDRAITVFSPDGHLFQVEYAQEAVKKGSTAVG+RG Sbjct: 5 YDRAITVFSPDGHLFQVEYAQEAVKKGSTAVGIRG------------------------- 39 Query: 63 CALDDNVCMAFAGLTADARIVINRARVECQSHRLTVEDPVTVEYITRYIASLKQRYTQSN 122 LTADAR+VINRARVECQSH+LTVEDPVTVEYITR+IA+LKQ+YTQSN Sbjct: 40 -------------LTADARVVINRARVECQSHKLTVEDPVTVEYITRFIATLKQKYTQSN 86 Query: 123 GRRPFGISALIVGFDFDGTPRLYQTDPSGTYHAWKANAIGRGAKSVREFLEKNYTDEAIE 182 GRRPFGISALIVGFD DG RLYQTDPSGTYHAWKANAIGR AK+VREFLEKNYT++AI Sbjct: 87 GRRPFGISALIVGFDDDGISRLYQTDPSGTYHAWKANAIGRSAKTVREFLEKNYTEDAIA 146 Query: 183 TDDLTIKLVIKALLEVVQSGGKNIELAVMRRDQSLKILNPEEIEKYVAEIEKEKEENEKK 242 +D IKL IKALLEVVQSGGKNIELA++RR+Q LK+ + +E+E YV EIEKEKEE EKK Sbjct: 147 SDSEAIKLAIKALLEVVQSGGKNIELAIIRRNQPLKMFSAKEVELYVTEIEKEKEEAEKK 206 Query: 243 KQKKA 247 K KK+ Sbjct: 207 KSKKS 211 >gi|156713442 proteasome alpha 4 subunit isoform 1 [Homo sapiens] Length = 261 Score = 162 bits (410), Expect = 3e-40 Identities = 86/251 (34%), Positives = 149/251 (59%), Gaps = 8/251 (3%) Query: 3 YDRAITVFSPDGHLFQVEYAQEAVKKGSTAVGVRGRDIVVLGVEKKSVAKLQDERTV-RK 61 YD T+FSP+G L+QVEYA EA+ T +G+ D V+L E++++ KL DE K Sbjct: 5 YDSRTTIFSPEGRLYQVEYAMEAIGHAGTCLGILANDGVLLAAERRNIHKLLDEVFFSEK 64 Query: 62 ICALDDNVCMAFAGLTADARIVINRARVECQSHRLTVEDPVTVEYITRYIASLKQRYTQS 121 I L++++ + AG+T+DA ++ N R+ Q + L ++P+ E + + +KQ YTQ Sbjct: 65 IYKLNEDMACSVAGITSDANVLTNELRLIAQRYLLQYQEPIPCEQLVTALCDIKQAYTQF 124 Query: 122 NGRRPFGISALIVGFDFDGTPRLYQTDPSGTYHAWKANAIGRGAKSVREFLEKNYTDEAI 181 G+RPFG+S L +G+D +LYQ+DPSG Y WKA IG + + L+++Y E Sbjct: 125 GGKRPFGVSLLYIGWDKHYGFQLYQSDPSGNYGGWKATCIGNNSAAAVSMLKQDY-KEGE 183 Query: 182 ETDDLTIKLVIKAL---LEVVQSGGKNIELAVMRRDQS---LKILNPEEIEKYVAEIEKE 235 T + L IK L ++V + + +E+A + R+ +++L +E+E+ + + E+E Sbjct: 184 MTLKSALALAIKVLNKTMDVSKLSAEKVEIATLTRENGKTVIRVLKQKEVEQLIKKHEEE 243 Query: 236 KEENEKKKQKK 246 + + E++K++K Sbjct: 244 EAKAEREKKEK 254 >gi|4506185 proteasome alpha 4 subunit isoform 1 [Homo sapiens] Length = 261 Score = 162 bits (410), Expect = 3e-40 Identities = 86/251 (34%), Positives = 149/251 (59%), Gaps = 8/251 (3%) Query: 3 YDRAITVFSPDGHLFQVEYAQEAVKKGSTAVGVRGRDIVVLGVEKKSVAKLQDERTV-RK 61 YD T+FSP+G L+QVEYA EA+ T +G+ D V+L E++++ KL DE K Sbjct: 5 YDSRTTIFSPEGRLYQVEYAMEAIGHAGTCLGILANDGVLLAAERRNIHKLLDEVFFSEK 64 Query: 62 ICALDDNVCMAFAGLTADARIVINRARVECQSHRLTVEDPVTVEYITRYIASLKQRYTQS 121 I L++++ + AG+T+DA ++ N R+ Q + L ++P+ E + + +KQ YTQ Sbjct: 65 IYKLNEDMACSVAGITSDANVLTNELRLIAQRYLLQYQEPIPCEQLVTALCDIKQAYTQF 124 Query: 122 NGRRPFGISALIVGFDFDGTPRLYQTDPSGTYHAWKANAIGRGAKSVREFLEKNYTDEAI 181 G+RPFG+S L +G+D +LYQ+DPSG Y WKA IG + + L+++Y E Sbjct: 125 GGKRPFGVSLLYIGWDKHYGFQLYQSDPSGNYGGWKATCIGNNSAAAVSMLKQDY-KEGE 183 Query: 182 ETDDLTIKLVIKAL---LEVVQSGGKNIELAVMRRDQS---LKILNPEEIEKYVAEIEKE 235 T + L IK L ++V + + +E+A + R+ +++L +E+E+ + + E+E Sbjct: 184 MTLKSALALAIKVLNKTMDVSKLSAEKVEIATLTRENGKTVIRVLKQKEVEQLIKKHEEE 243 Query: 236 KEENEKKKQKK 246 + + E++K++K Sbjct: 244 EAKAEREKKEK 254 >gi|4506181 proteasome subunit alpha type 2 [Homo sapiens] Length = 234 Score = 160 bits (405), Expect = 1e-39 Identities = 89/235 (37%), Positives = 140/235 (59%), Gaps = 12/235 (5%) Query: 3 YDRAITVFSPDGHLFQVEYAQEAVKKGSTAVGVRGRDIVVLGVEKKSVAKLQDERTVRKI 62 Y ++T FSP G L Q+EYA AV G+ +VG++ + VVL EKK + L DER+V K+ Sbjct: 6 YSFSLTTFSPSGKLVQIEYALAAVAGGAPSVGIKAANGVVLATEKKQKSILYDERSVHKV 65 Query: 63 CALDDNVCMAFAGLTADARIVINRARVECQSHRLTVEDPVTVEYITRYIASLKQRYTQSN 122 + ++ + ++G+ D R++++RAR Q + L ++P+ + + +AS+ Q YTQS Sbjct: 66 EPITKHIGLVYSGMGPDYRVLVHRARKLAQQYYLVYQEPIPTAQLVQRVASVMQEYTQSG 125 Query: 123 GRRPFGISALIVGFDFDGTPRLYQTDPSGTYHAWKANAIGRGAKSVREFLEKNYT----- 177 G RPFG+S LI G++ +G P L+Q+DPSG Y AWKA A+G+ + + FLEK Y Sbjct: 126 GVRPFGVSLLICGWN-EGRPYLFQSDPSGAYFAWKATAMGKNYVNGKTFLEKRYNEDLEL 184 Query: 178 DEAIETDDLTIKLVIKALLEVVQSGGKNIELAVMRRDQSLKILNPEEIEKYVAEI 232 ++AI T LT+K + Q NIE+ + + + L P E++ Y+A I Sbjct: 185 EDAIHTAILTLKESFEG-----QMTEDNIEVGIC-NEAGFRRLTPTEVKDYLAAI 233 >gi|23110942 proteasome alpha 5 subunit [Homo sapiens] Length = 241 Score = 152 bits (384), Expect = 3e-37 Identities = 87/240 (36%), Positives = 143/240 (59%), Gaps = 16/240 (6%) Query: 3 YDRAITVFSPDGHLFQVEYAQEAVKKGSTAVGVRGRDIVVLGVEKKSVAKLQDERTVRKI 62 YDR + FSP+G LFQVEYA EA+K GSTA+G++ + V L VEK+ + L + ++ KI Sbjct: 8 YDRGVNTFSPEGRLFQVEYAIEAIKLGSTAIGIQTSEGVCLAVEKRITSPLMEPSSIEKI 67 Query: 63 CALDDNVCMAFAGLTADARIVINRARVECQSHRLTVEDPVTVEYITRYIASLKQRYTQSN 122 +D ++ A +GL ADA+ +I++ARVE Q+H T + +TVE +T+ +++L ++ + + Sbjct: 68 VEIDAHIGCAMSGLIADAKTLIDKARVETQNHWFTYNETMTVESVTQAVSNLALQFGEED 127 Query: 123 G-----RRPFGISALIVGFDFDGTPRLYQTDPSGTYHAWKANAIGRGAKSVREFLEKNY- 176 RPFG++ L G D G P+L+ DPSGT+ A AIG ++ + L++ Y Sbjct: 128 ADPGAMSRPFGVALLFGGVDEKG-PQLFHMDPSGTFVQCDARAIGSASEGAQSSLQEVYH 186 Query: 177 ----TDEAIETDDLTIKLVIKALLEVVQSGGKNIELAVMRRDQSLKILNPEEIEKYVAEI 232 EAI++ + +K V++ L NIELA ++ Q+ + EE+E+ + +I Sbjct: 187 KSMTLKEAIKSSLIILKQVMEEKLNAT-----NIELATVQPGQNFHMFTKEELEEVIKDI 241 >gi|4506179 proteasome alpha 1 subunit isoform 2 [Homo sapiens] Length = 263 Score = 138 bits (347), Expect = 5e-33 Identities = 79/246 (32%), Positives = 139/246 (56%), Gaps = 7/246 (2%) Query: 3 YDRAITVFSPDGHLFQVEYAQEAVKKGSTAVGVRGRDIVVLGVEKKSVAKLQDERTVRKI 62 YD +TV+SP G + Q+EYA EAVK+GS VG++ + VL K++ ++L + +KI Sbjct: 6 YDNDVTVWSPQGRIHQIEYAMEAVKQGSATVGLKSKTHAVLVALKRAQSELAAHQ--KKI 63 Query: 63 CALDDNVCMAFAGLTADARIVINRARVECQSHRLTVEDPVTVEYITRYIASLKQRYTQSN 122 +D+++ ++ AGLTADAR++ N R EC R + P+ V + I S Q TQ Sbjct: 64 LHVDNHIGISIAGLTADARLLCNFMRQECLDSRFVFDRPLPVSRLVSLIGSKTQIPTQRY 123 Query: 123 GRRPFGISALIVGFDFDGTPRLYQTDPSGTYHAWKANAIGRGAKSVREFLEKNYTDEAIE 182 GRRP+G+ LI G+D D P ++QT PS Y +A +IG ++S R +LE++ ++ Sbjct: 124 GRRPYGVGLLIAGYD-DMGPHIFQTCPSANYFDCRAMSIGARSQSARTYLERHMSEFMEC 182 Query: 183 TDDLTIKLVIKALLEVVQS----GGKNIELAVMRRDQSLKILNPEEIEKYVAEIEKEKEE 238 + +K ++AL E + + KN+ + ++ +D I + +++ ++ +E+ + Sbjct: 183 NLNELVKHGLRALRETLPAEQDLTTKNVSIGIVGKDLEFTIYDDDDVSPFLEGLEERPQR 242 Query: 239 NEKKKQ 244 + Q Sbjct: 243 KAQPAQ 248 >gi|23110935 proteasome alpha 1 subunit isoform 1 [Homo sapiens] Length = 269 Score = 138 bits (347), Expect = 5e-33 Identities = 79/246 (32%), Positives = 139/246 (56%), Gaps = 7/246 (2%) Query: 3 YDRAITVFSPDGHLFQVEYAQEAVKKGSTAVGVRGRDIVVLGVEKKSVAKLQDERTVRKI 62 YD +TV+SP G + Q+EYA EAVK+GS VG++ + VL K++ ++L + +KI Sbjct: 12 YDNDVTVWSPQGRIHQIEYAMEAVKQGSATVGLKSKTHAVLVALKRAQSELAAHQ--KKI 69 Query: 63 CALDDNVCMAFAGLTADARIVINRARVECQSHRLTVEDPVTVEYITRYIASLKQRYTQSN 122 +D+++ ++ AGLTADAR++ N R EC R + P+ V + I S Q TQ Sbjct: 70 LHVDNHIGISIAGLTADARLLCNFMRQECLDSRFVFDRPLPVSRLVSLIGSKTQIPTQRY 129 Query: 123 GRRPFGISALIVGFDFDGTPRLYQTDPSGTYHAWKANAIGRGAKSVREFLEKNYTDEAIE 182 GRRP+G+ LI G+D D P ++QT PS Y +A +IG ++S R +LE++ ++ Sbjct: 130 GRRPYGVGLLIAGYD-DMGPHIFQTCPSANYFDCRAMSIGARSQSARTYLERHMSEFMEC 188 Query: 183 TDDLTIKLVIKALLEVVQS----GGKNIELAVMRRDQSLKILNPEEIEKYVAEIEKEKEE 238 + +K ++AL E + + KN+ + ++ +D I + +++ ++ +E+ + Sbjct: 189 NLNELVKHGLRALRETLPAEQDLTTKNVSIGIVGKDLEFTIYDDDDVSPFLEGLEERPQR 248 Query: 239 NEKKKQ 244 + Q Sbjct: 249 KAQPAQ 254 >gi|23110944 proteasome alpha 6 subunit [Homo sapiens] Length = 246 Score = 132 bits (333), Expect = 2e-31 Identities = 78/234 (33%), Positives = 125/234 (53%), Gaps = 4/234 (1%) Query: 3 YDRAITVFSPDGHLFQVEYAQEAVKKGS-TAVGVRGRDIVVLGVEKKSVAKLQDERTVRK 61 +DR IT+FSP+G L+QVEYA +A+ +G T+V VRG+D V+ +KK KL D TV Sbjct: 9 FDRHITIFSPEGRLYQVEYAFKAINQGGLTSVAVRGKDCAVIVTQKKVPDKLLDSSTVTH 68 Query: 62 ICALDDNVCMAFAGLTADARIVINRARVECQSHRLTVEDPVTVEYITRYIASLKQRYTQS 121 + + +N+ G+TAD+R + RAR E + + + V+ + + IA + Q YTQ+ Sbjct: 69 LFKITENIGCVMTGMTADSRSQVQRARYEAANWKYKYGYEIPVDMLCKRIADISQVYTQN 128 Query: 122 NGRRPFGISALIVGFDFDGTPRLYQTDPSGTYHAWKANAIGRGAKSVREFLEKNYTDEAI 181 RP G +++G D + P++Y+ DP+G Y +KA A G FLEK + Sbjct: 129 AEMRPLGCCMILIGIDEEQGPQVYKCDPAGYYCGFKATAAGVKQTESTSFLEKKVKKKFD 188 Query: 182 ETDDLTIKLVIKALLEVVQSGGKNIEL---AVMRRDQSLKILNPEEIEKYVAEI 232 T + T++ I L V+ K E+ V + +IL EI+ ++ + Sbjct: 189 WTFEQTVETAITCLSTVLSIDFKPSEIEVGVVTVENPKFRILTEAEIDAHLVAL 242 >gi|4506183 proteasome alpha 3 subunit isoform 1 [Homo sapiens] Length = 255 Score = 125 bits (315), Expect = 3e-29 Identities = 79/250 (31%), Positives = 137/250 (54%), Gaps = 18/250 (7%) Query: 3 YDRAITVFSPDGHLFQVEYAQEAVKKGSTAVGVRGRDIVVLGVEKKSVAKLQDERTVRKI 62 YD + + FSPDG +FQVEYA +AV+ STA+G+R +D VV GVEK ++KL +E + +++ Sbjct: 8 YDLSASTFSPDGRVFQVEYAMKAVENSSTAIGIRCKDGVVFGVEKLVLSKLYEEGSNKRL 67 Query: 63 CALDDNVCMAFAGLTADARIVINRARVECQSHRLTVEDPVTVEYITRYIASLKQRYTQSN 122 +D +V MA AGL ADAR + + AR E + R + ++++ +A YT + Sbjct: 68 FNVDRHVGMAVAGLLADARSLADIAREEASNFRSNFGYNIPLKHLADRVAMYVHAYTLYS 127 Query: 123 GRRPFGISALIVGFDFDGTPRLYQTDPSGTYHAWKANAIGRGAKSVREFLEKNYTDEAIE 182 RPFG S ++ + + +LY DPSG + + AIG+ ++ + +EK ++ Sbjct: 128 AVRPFGCSFMLGSYSVNDGAQLYMIDPSGVSYGYWGCAIGKARQAAKTEIEK------LQ 181 Query: 183 TDDLTIKLVIKALLEVV-----QSGGKNIELAVM-------RRDQSLKILNPEEIEKYVA 230 ++T + ++K + +++ + K EL + R + + EE EKY Sbjct: 182 MKEMTCRDIVKEVAKIIYIVHDEVKDKAFELELSWVGELTNGRHEIVPKDIREEAEKYAK 241 Query: 231 EIEKEKEENE 240 E KE++E++ Sbjct: 242 ESLKEEDESD 251 >gi|23110939 proteasome alpha 3 subunit isoform 2 [Homo sapiens] Length = 248 Score = 119 bits (297), Expect = 3e-27 Identities = 81/250 (32%), Positives = 135/250 (54%), Gaps = 25/250 (10%) Query: 3 YDRAITVFSPDGHLFQVEYAQEAVKKGSTAVGVRGRDIVVLGVEKKSVAKLQDERTVRKI 62 YD + + FSPDG +FQVEYA +AV+ STA+G+R +D VV GVEK ++KL +E + +++ Sbjct: 8 YDLSASTFSPDGRVFQVEYAMKAVENSSTAIGIRCKDGVVFGVEKLVLSKLYEEGSNKRL 67 Query: 63 CALDDNVCMAFAGLTADARIVINRARVECQSHRLTVEDPVTVEYITRYIASLKQRYTQSN 122 +D +V MA AGL ADAR + + AR E + R + ++++ +A YT + Sbjct: 68 FNVDRHVGMAVAGLLADARSLADIAREEASNFRSNFGYNIPLKHLADRVAMYVHAYTLYS 127 Query: 123 GRRPFGISALIVGFDFDGTPRLYQTDPSGTYHAWKANAIGRGAKSVREFLEKNYTDEAIE 182 RPFG S DG +LY DPSG + + AIG+ ++ + +EK ++ Sbjct: 128 AVRPFGCSV------NDGA-QLYMIDPSGVSYGYWGCAIGKARQAAKTEIEK------LQ 174 Query: 183 TDDLTIKLVIKALLEVV-----QSGGKNIELAVM-------RRDQSLKILNPEEIEKYVA 230 ++T + ++K + +++ + K EL + R + + EE EKY Sbjct: 175 MKEMTCRDIVKEVAKIIYIVHDEVKDKAFELELSWVGELTNGRHEIVPKDIREEAEKYAK 234 Query: 231 EIEKEKEENE 240 E KE++E++ Sbjct: 235 ESLKEEDESD 244 >gi|156713444 proteasome alpha 4 subunit isoform 2 [Homo sapiens] Length = 190 Score = 111 bits (277), Expect = 7e-25 Identities = 58/179 (32%), Positives = 105/179 (58%), Gaps = 7/179 (3%) Query: 74 AGLTADARIVINRARVECQSHRLTVEDPVTVEYITRYIASLKQRYTQSNGRRPFGISALI 133 AG+T+DA ++ N R+ Q + L ++P+ E + + +KQ YTQ G+RPFG+S L Sbjct: 6 AGITSDANVLTNELRLIAQRYLLQYQEPIPCEQLVTALCDIKQAYTQFGGKRPFGVSLLY 65 Query: 134 VGFDFDGTPRLYQTDPSGTYHAWKANAIGRGAKSVREFLEKNYTDEAIETDDLTIKLVIK 193 +G+D +LYQ+DPSG Y WKA IG + + L+++Y E T + L IK Sbjct: 66 IGWDKHYGFQLYQSDPSGNYGGWKATCIGNNSAAAVSMLKQDY-KEGEMTLKSALALAIK 124 Query: 194 AL---LEVVQSGGKNIELAVMRRDQS---LKILNPEEIEKYVAEIEKEKEENEKKKQKK 246 L ++V + + +E+A + R+ +++L +E+E+ + + E+E+ + E++K++K Sbjct: 125 VLNKTMDVSKLSAEKVEIATLTRENGKTVIRVLKQKEVEQLIKKHEEEEAKAEREKKEK 183 >gi|221316716 proteasome alpha 1 subunit isoform 3 [Homo sapiens] Length = 130 Score = 82.0 bits (201), Expect = 4e-16 Identities = 43/111 (38%), Positives = 68/111 (61%), Gaps = 2/111 (1%) Query: 3 YDRAITVFSPDGHLFQVEYAQEAVKKGSTAVGVRGRDIVVLGVEKKSVAKLQDERTVRKI 62 YD +TV+SP G + Q+EYA EAVK+GS VG++ + VL K++ ++L + +KI Sbjct: 6 YDNDVTVWSPQGRIHQIEYAMEAVKQGSATVGLKSKTHAVLVALKRAQSELAAHQ--KKI 63 Query: 63 CALDDNVCMAFAGLTADARIVINRARVECQSHRLTVEDPVTVEYITRYIAS 113 +D+++ ++ AGLTADAR++ N R EC R + P+ V + I S Sbjct: 64 LHVDNHIGISIAGLTADARLLCNFMRQECLDSRFVFDRPLPVSRLVSLIGS 114 >gi|4506191 proteasome beta 10 subunit proprotein [Homo sapiens] Length = 273 Score = 55.1 bits (131), Expect = 6e-08 Identities = 51/194 (26%), Positives = 87/194 (44%), Gaps = 14/194 (7%) Query: 25 AVKKGSTAVGVRGRDIVVLGVEKKSVA-KLQDERTVRKICALDDNVCMAFAGLTADARIV 83 A K G+T G+ +D V+LG + ++ + +++ KI + + AG+ ADA + Sbjct: 35 ARKTGTTIAGLVFQDGVILGADTRATNDSVVADKSCEKIHFIAPKIYCCGAGVAADAEMT 94 Query: 84 INRARVECQSHRLTVEDPVTVEYITRYIASLKQRYTQSNGRRPFGISALIVGFDFDGTPR 143 + + H L+ V +TR + RY + G S ++ G D G P+ Sbjct: 95 TRMVASKMELHALSTGREPRVATVTRILRQTLFRY-----QGHVGASLIVGGVDLTG-PQ 148 Query: 144 LYQTDPSGTYHAWKANAIGRGAKSVREFLE----KNYTDEAIETDDLTIKLVIKALLEVV 199 LY P G+Y A+G G + LE N T EA + L ++ V +L + Sbjct: 149 LYGVHPHGSYSRLPFTALGSGQDAALAVLEDRFQPNMTLEAAQ--GLLVEAVTAGILGDL 206 Query: 200 QSGGKNIELAVMRR 213 SGG N++ V+ + Sbjct: 207 GSGG-NVDACVITK 219 >gi|169206322 PREDICTED: similar to hCG30646 [Homo sapiens] Length = 272 Score = 54.3 bits (129), Expect = 1e-07 Identities = 48/172 (27%), Positives = 71/172 (41%), Gaps = 41/172 (23%) Query: 3 YDRAITVFSPDGHLFQVEYAQEAVKKGS-TAVGVRGRDIVVLGVEKKSVAKLQDERTVRK 61 +DR + +FSP L+QV+YA +A+ +G T+V VR +D V+ K KL D RT Sbjct: 93 FDRHLIIFSPKVQLYQVQYAFKAINQGGLTSVAVRKKDCAVIVTHKIVPDKLLDSRT--H 150 Query: 62 ICALDDNVCMAFAGLTADARIVINRARVECQSHRLTVEDPVTVEYITRYIASLKQRYTQS 121 + + N G+TAD+R RA+ + A+ K + Sbjct: 151 LFKMTKNTGRVITGVTADSRSREQRAQYKA--------------------ANCKYNIFEE 190 Query: 122 NGRRPFGISALIVGFDFDGTPRLYQTDPSGTYHAWKANAIGRGAKSVREFLE 173 G PR+Y+ D +G Y +KA A G FLE Sbjct: 191 LG------------------PRVYKCDAAGYYCGFKATAAGVKQAESTSFLE 224 >gi|239750562 PREDICTED: similar to hCG30646 [Homo sapiens] Length = 272 Score = 54.3 bits (129), Expect = 1e-07 Identities = 48/172 (27%), Positives = 71/172 (41%), Gaps = 41/172 (23%) Query: 3 YDRAITVFSPDGHLFQVEYAQEAVKKGS-TAVGVRGRDIVVLGVEKKSVAKLQDERTVRK 61 +DR + +FSP L+QV+YA +A+ +G T+V VR +D V+ K KL D RT Sbjct: 93 FDRHLIIFSPKVQLYQVQYAFKAINQGGLTSVAVRKKDCAVIVTHKIVPDKLLDSRT--H 150 Query: 62 ICALDDNVCMAFAGLTADARIVINRARVECQSHRLTVEDPVTVEYITRYIASLKQRYTQS 121 + + N G+TAD+R RA+ + A+ K + Sbjct: 151 LFKMTKNTGRVITGVTADSRSREQRAQYKA--------------------ANCKYNIFEE 190 Query: 122 NGRRPFGISALIVGFDFDGTPRLYQTDPSGTYHAWKANAIGRGAKSVREFLE 173 G PR+Y+ D +G Y +KA A G FLE Sbjct: 191 LG------------------PRVYKCDAAGYYCGFKATAAGVKQAESTSFLE 224 >gi|239744861 PREDICTED: similar to hCG30646 [Homo sapiens] Length = 272 Score = 54.3 bits (129), Expect = 1e-07 Identities = 48/172 (27%), Positives = 71/172 (41%), Gaps = 41/172 (23%) Query: 3 YDRAITVFSPDGHLFQVEYAQEAVKKGS-TAVGVRGRDIVVLGVEKKSVAKLQDERTVRK 61 +DR + +FSP L+QV+YA +A+ +G T+V VR +D V+ K KL D RT Sbjct: 93 FDRHLIIFSPKVQLYQVQYAFKAINQGGLTSVAVRKKDCAVIVTHKIVPDKLLDSRT--H 150 Query: 62 ICALDDNVCMAFAGLTADARIVINRARVECQSHRLTVEDPVTVEYITRYIASLKQRYTQS 121 + + N G+TAD+R RA+ + A+ K + Sbjct: 151 LFKMTKNTGRVITGVTADSRSREQRAQYKA--------------------ANCKYNIFEE 190 Query: 122 NGRRPFGISALIVGFDFDGTPRLYQTDPSGTYHAWKANAIGRGAKSVREFLE 173 G PR+Y+ D +G Y +KA A G FLE Sbjct: 191 LG------------------PRVYKCDAAGYYCGFKATAAGVKQAESTSFLE 224 >gi|4506201 proteasome beta 5 subunit isoform 1 [Homo sapiens] Length = 263 Score = 42.7 bits (99), Expect = 3e-04 Identities = 39/194 (20%), Positives = 86/194 (44%), Gaps = 9/194 (4%) Query: 29 GSTAVGVRGRDIVVLGVEKKSVAKLQ-DERTVRKICALDDNVCMAFAGLTADARIVINRA 87 G+T + + R V++ + ++ A +TV+K+ ++ + AG AD Sbjct: 59 GTTTLAFKFRHGVIVAADSRATAGAYIASQTVKKVIEINPYLLGTMAGGAADCSFWERLL 118 Query: 88 RVECQSHRLTVEDPVTVEYITRYIASLKQRYTQSNGRRPFGISALIVGFDFDGTPRLYQT 147 +C+ + L ++ ++V ++ +A++ +Y + +I G+D G P LY Sbjct: 119 ARQCRIYELRNKERISVAAASKLLANMVYQYKGMG----LSMGTMICGWDKRG-PGLYYV 173 Query: 148 DPSGTYHAWKANAIGRGAKSVREFLEKNYTD--EAIETDDLTIKLVIKALLEVVQSGGKN 205 D G + ++G G+ +++ Y+ E + DL + + +A SGG Sbjct: 174 DSEGNRISGATFSVGSGSVYAYGVMDRGYSYDLEVEQAYDLARRAIYQATYRDAYSGGA- 232 Query: 206 IELAVMRRDQSLKI 219 + L +R D +++ Sbjct: 233 VNLYHVREDGWIRV 246 >gi|4506203 proteasome beta 7 subunit proprotein [Homo sapiens] Length = 277 Score = 42.4 bits (98), Expect = 4e-04 Identities = 46/199 (23%), Positives = 81/199 (40%), Gaps = 11/199 (5%) Query: 27 KKGSTAVGVRGRDIVVLGVEKKSV-AKLQDERTVRKICALDDNVCMAFAGLTADARIVIN 85 K G+T GV +D +VLG + ++ + ++ KI + N+ AG AD + Sbjct: 41 KTGTTIAGVVYKDGIVLGADTRATEGMVVADKNCSKIHFISPNIYCCGAGTAADTDMTTQ 100 Query: 86 RARVECQSHRLTVEDPVTVEYITRYIASLKQRYTQSNGRRPFGISALIVGFDFDGTPRLY 145 + H L+ V R + + RY + G + ++ G D G P LY Sbjct: 101 LISSNLELHSLSTGRLPRVVTANRMLKQMLFRY-----QGYIGAALVLGGVDVTG-PHLY 154 Query: 146 QTDPSGTYHAWKANAIGRGAKSVREFLEKNYTD--EAIETDDLTIKLVIKALLEVVQSGG 203 P G+ +G G+ + E + E E +L + + + + S G Sbjct: 155 SIYPHGSTDKLPYVTMGSGSLAAMAVFEDKFRPDMEEEEAKNLVSEAIAAGIFNDLGS-G 213 Query: 204 KNIELAVMRRDQSLKILNP 222 NI+L V+ +++ L L P Sbjct: 214 SNIDLCVISKNK-LDFLRP 231 >gi|23110932 proteasome beta 9 subunit isoform 2 proprotein [Homo sapiens] Length = 209 Score = 38.1 bits (87), Expect = 0.007 Identities = 28/123 (22%), Positives = 54/123 (43%), Gaps = 6/123 (4%) Query: 26 VKKGSTAVGVRGRDIVVLGVEKK-SVAKLQDERTVRKICALDDNVCMAFAGLTADARIVI 84 V G+T + V VV+G + + S + R K+ L + + A +G ADA+ V Sbjct: 7 VHTGTTIMAVEFDGGVVMGSDSRVSAGEAVVNRVFDKLSPLHERIYCALSGSAADAQAVA 66 Query: 85 NRARVECQSHRLTVEDPVTVEYITRYIASLKQRYTQSNGRRPFGISALIVGFDFDGTPRL 144 + A + + H + +E+P V + ++ +Y R ++ G+D ++ Sbjct: 67 DMAAYQLELHGIELEEPPLVLAAANVVRNISYKY-----REDLSAHLMVAGWDQREGGQV 121 Query: 145 YQT 147 Y T Sbjct: 122 YGT 124 >gi|4506205 proteasome beta 9 subunit isoform 1 proprotein [Homo sapiens] Length = 219 Score = 38.1 bits (87), Expect = 0.007 Identities = 28/123 (22%), Positives = 54/123 (43%), Gaps = 6/123 (4%) Query: 26 VKKGSTAVGVRGRDIVVLGVEKK-SVAKLQDERTVRKICALDDNVCMAFAGLTADARIVI 84 V G+T + V VV+G + + S + R K+ L + + A +G ADA+ V Sbjct: 17 VHTGTTIMAVEFDGGVVMGSDSRVSAGEAVVNRVFDKLSPLHERIYCALSGSAADAQAVA 76 Query: 85 NRARVECQSHRLTVEDPVTVEYITRYIASLKQRYTQSNGRRPFGISALIVGFDFDGTPRL 144 + A + + H + +E+P V + ++ +Y R ++ G+D ++ Sbjct: 77 DMAAYQLELHGIELEEPPLVLAAANVVRNISYKY-----REDLSAHLMVAGWDQREGGQV 131 Query: 145 YQT 147 Y T Sbjct: 132 YGT 134 >gi|239787084 zinc finger protein 611 isoform a [Homo sapiens] Length = 705 Score = 32.0 bits (71), Expect = 0.51 Identities = 22/75 (29%), Positives = 43/75 (57%), Gaps = 4/75 (5%) Query: 169 REFLEKNYTDEAIETDDLTIKLVIKALLEVVQSGGKNIELAVMRRDQSLKILNP--EEIE 226 RE + +NY + +E D++ K ++K +L Q + I ++R +S I + +EIE Sbjct: 50 REVMLENYRN--LEAVDISSKCMMKEVLSTGQGNTEVIHTGTLQRHESHHIGDFCFQEIE 107 Query: 227 KYVAEIEKEKEENEK 241 K + +IE + +E+E+ Sbjct: 108 KEIHDIEFQCQEDER 122 >gi|239787082 zinc finger protein 611 isoform a [Homo sapiens] Length = 705 Score = 32.0 bits (71), Expect = 0.51 Identities = 22/75 (29%), Positives = 43/75 (57%), Gaps = 4/75 (5%) Query: 169 REFLEKNYTDEAIETDDLTIKLVIKALLEVVQSGGKNIELAVMRRDQSLKILNP--EEIE 226 RE + +NY + +E D++ K ++K +L Q + I ++R +S I + +EIE Sbjct: 50 REVMLENYRN--LEAVDISSKCMMKEVLSTGQGNTEVIHTGTLQRHESHHIGDFCFQEIE 107 Query: 227 KYVAEIEKEKEENEK 241 K + +IE + +E+E+ Sbjct: 108 KEIHDIEFQCQEDER 122 >gi|239787080 zinc finger protein 611 isoform a [Homo sapiens] Length = 705 Score = 32.0 bits (71), Expect = 0.51 Identities = 22/75 (29%), Positives = 43/75 (57%), Gaps = 4/75 (5%) Query: 169 REFLEKNYTDEAIETDDLTIKLVIKALLEVVQSGGKNIELAVMRRDQSLKILNP--EEIE 226 RE + +NY + +E D++ K ++K +L Q + I ++R +S I + +EIE Sbjct: 50 REVMLENYRN--LEAVDISSKCMMKEVLSTGQGNTEVIHTGTLQRHESHHIGDFCFQEIE 107 Query: 227 KYVAEIEKEKEENEK 241 K + +IE + +E+E+ Sbjct: 108 KEIHDIEFQCQEDER 122 >gi|16507237 heat shock 70kDa protein 5 [Homo sapiens] Length = 654 Score = 32.0 bits (71), Expect = 0.51 Identities = 20/63 (31%), Positives = 34/63 (53%), Gaps = 4/63 (6%) Query: 185 DLTIKLVIKALLEVV--QSGGKNIELAVMRRDQSLKILNPEEIEKYVAEIEKEKEENEKK 242 ++T ++ + +L V G N + DQ+ L PEEIE+ V + EK EE++K Sbjct: 498 EVTFEIDVNGILRVTAEDKGTGNKNKITITNDQNR--LTPEEIERMVNDAEKFAEEDKKL 555 Query: 243 KQK 245 K++ Sbjct: 556 KER 558 >gi|51988900 XPG-complementing protein [Homo sapiens] Length = 1186 Score = 32.0 bits (71), Expect = 0.51 Identities = 18/41 (43%), Positives = 26/41 (63%), Gaps = 1/41 (2%) Query: 208 LAVMRRDQSLKILNP-EEIEKYVAEIEKEKEENEKKKQKKA 247 L +RR+ L +L P +E EK+ +E E EKE E+ QK+A Sbjct: 134 LTQVRRENDLYVLPPLQEEEKHSSEEEDEKEWQERMNQKQA 174 >gi|21361831 partitioning-defective protein 3 homolog [Homo sapiens] Length = 1356 Score = 32.0 bits (71), Expect = 0.51 Identities = 23/86 (26%), Positives = 46/86 (53%), Gaps = 2/86 (2%) Query: 162 GRGA-KSVREFLEKNYTDEAIETDDLTIKLVIKALLEVVQSGGKNIELAVMRRDQSL-KI 219 GRG +S R ++K+Y A++ DD ++ + + E +SG +++ A + SL + Sbjct: 918 GRGCNESFRAAIDKSYDKPAVDDDDEGMETLEEDTEESSRSGRESVSTASDQPSHSLERQ 977 Query: 220 LNPEEIEKYVAEIEKEKEENEKKKQK 245 +N + + + +K+K EKKK + Sbjct: 978 MNGNQEKGDKTDRKKDKTGKEKKKDR 1003 >gi|4506193 proteasome beta 1 subunit [Homo sapiens] Length = 241 Score = 31.2 bits (69), Expect = 0.88 Identities = 30/149 (20%), Positives = 56/149 (37%), Gaps = 5/149 (3%) Query: 26 VKKGSTAVGVRGRDIVVLGVEKK-SVAKLQDERTVRKICALDDNVCMAFAGLTADARIVI 84 V G T + + G D ++ + + S R K L D + +G D + Sbjct: 34 VFNGGTILAIAGEDFAIVASDTRLSEGFSIHTRDSPKCYKLTDKTVIGCSGFHGDCLTLT 93 Query: 85 NRARVECQSHRLTVEDPVTVEYITRYIASLKQRYTQSNGRRPFGISALIVGFDFDGTPRL 144 + ++ + +T T IA++ S P+ + +I G D +G + Sbjct: 94 KIIEARLKMYKHSNNKAMT----TGAIAAMLSTILYSRRFFPYYVYNIIGGLDEEGKGAV 149 Query: 145 YQTDPSGTYHAWKANAIGRGAKSVREFLE 173 Y DP G+Y A G + ++ L+ Sbjct: 150 YSFDPVGSYQRDSFKAGGSASAMLQPLLD 178 Database: hs.faa Posted date: Aug 4, 2009 4:42 PM Number of letters in database: 18,247,518 Number of sequences in database: 37,866 Lambda K H 0.316 0.133 0.367 Gapped Lambda K H 0.267 0.0410 0.140 Matrix: BLOSUM62 Gap Penalties: Existence: 11, Extension: 1 Number of Hits to DB: 8,501,884 Number of Sequences: 37866 Number of extensions: 352865 Number of successful extensions: 2769 Number of sequences better than 10.0: 30 Number of HSP's better than 10.0 without gapping: 30 Number of HSP's successfully gapped in prelim test: 32 Number of HSP's that attempted gapping in prelim test: 2647 Number of HSP's gapped (non-prelim): 121 length of query: 248 length of database: 18,247,518 effective HSP length: 100 effective length of query: 148 effective length of database: 14,460,918 effective search space: 2140215864 effective search space used: 2140215864 T: 11 A: 40 X1: 16 ( 7.3 bits) X2: 38 (14.6 bits) X3: 64 (24.7 bits) S1: 41 (21.6 bits) S2: 60 (27.7 bits)
Search results were obtained with NCBI BLAST and RefSeq entries.
Guide to the Human Genome
Copyright © 2010 by Stewart Scherer. All rights reserved.