Home |
Table of Contents |
Search text |
Search genes |
Search sequences |
Purchase |
FAQ |
Blog |
Help
Search of human proteins with 4506121
BLASTP 2.2.11 [Jun-05-2005]
Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer,
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997),
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs", Nucleic Acids Res. 25:3389-3402.
Query= gi|4506121 protein Z, vitamin K-dependent plasma glycoprotein
[Homo sapiens]
(400 letters)
Database: hs.faa
37,866 sequences; 18,247,518 total letters
Searching..................................................done
Score E
Sequences producing significant alignments: (bits) Value
gi|4506121 protein Z, vitamin K-dependent plasma glycoprotein [H... 850 0.0
gi|4503625 coagulation factor X preproprotein [Homo sapiens] 191 8e-49
gi|4503649 coagulation factor IX preproprotein [Homo sapiens] 190 2e-48
gi|4506115 protein C [Homo sapiens] 178 7e-45
gi|10518503 coagulation factor VII isoform b precursor [Homo sap... 176 3e-44
gi|4503645 coagulation factor VII isoform a precursor [Homo sapi... 172 5e-43
gi|192447438 protein S, alpha preproprotein [Homo sapiens] 117 2e-26
gi|4557617 growth arrest-specific 6 isoform 1 precursor [Homo sa... 112 8e-25
gi|23957702 transmembrane protease, serine 6 [Homo sapiens] 87 3e-17
gi|122937283 6720455I24Rik homolog [Homo sapiens] 79 6e-15
gi|4503137 chymotrypsin-like [Homo sapiens] 75 1e-13
gi|31543811 proline rich Gla (G-carboxyglutamic acid) 3 (transme... 72 1e-12
gi|215422383 proline rich Gla (G-carboxyglutamic acid) 1 [Homo s... 71 2e-12
gi|4506135 proline rich Gla (G-carboxyglutamic acid) 1 [Homo sap... 71 2e-12
gi|189491647 fibulin 7 isoform 2 [Homo sapiens] 70 3e-12
gi|118498350 chymotrypsin B2 [Homo sapiens] 69 6e-12
gi|118498341 chymotrypsin B1 [Homo sapiens] 69 7e-12
gi|87196600 polyserase 3 [Homo sapiens] 69 1e-11
gi|134244285 Notch homolog 3 [Homo sapiens] 68 2e-11
gi|110347457 EGF-like-domain, multiple 3 [Homo sapiens] 67 3e-11
gi|4503635 coagulation factor II preproprotein [Homo sapiens] 66 5e-11
gi|41327708 crumbs homolog 1 precursor [Homo sapiens] 66 5e-11
gi|33667063 transmembrane protease, serine 9 [Homo sapiens] 66 6e-11
gi|78191798 plasma kallikrein B1 precursor [Homo sapiens] 65 8e-11
gi|29244926 corin [Homo sapiens] 65 8e-11
gi|148833508 notch1 preproprotein [Homo sapiens] 65 1e-10
gi|24041035 notch 2 preproprotein [Homo sapiens] 64 2e-10
gi|62526043 chymotrypsin C preproprotein [Homo sapiens] 63 5e-10
gi|110578663 hypothetical protein LOC203074 [Homo sapiens] 63 5e-10
gi|10190748 CEGP1 protein [Homo sapiens] 62 7e-10
>gi|4506121 protein Z, vitamin K-dependent plasma glycoprotein [Homo
sapiens]
Length = 400
Score = 850 bits (2196), Expect = 0.0
Identities = 400/400 (100%), Positives = 400/400 (100%)
Query: 1 MAGCVPLLQGLVLVLALHRVEPSVFLPASKANDVLVRWKRAGSYLLEELFEGNLEKECYE 60
MAGCVPLLQGLVLVLALHRVEPSVFLPASKANDVLVRWKRAGSYLLEELFEGNLEKECYE
Sbjct: 1 MAGCVPLLQGLVLVLALHRVEPSVFLPASKANDVLVRWKRAGSYLLEELFEGNLEKECYE 60
Query: 61 EICVYEEAREVFENEVVTDEFWRRYKGGSPCISQPCLHNGSCQDSIWGYTCTCSPGYEGS 120
EICVYEEAREVFENEVVTDEFWRRYKGGSPCISQPCLHNGSCQDSIWGYTCTCSPGYEGS
Sbjct: 61 EICVYEEAREVFENEVVTDEFWRRYKGGSPCISQPCLHNGSCQDSIWGYTCTCSPGYEGS 120
Query: 121 NCELAKNECHPERTDGCQHFCLPGQESYTCSCAQGYRLGEDHKQCVPHDQCACGVLTSEK 180
NCELAKNECHPERTDGCQHFCLPGQESYTCSCAQGYRLGEDHKQCVPHDQCACGVLTSEK
Sbjct: 121 NCELAKNECHPERTDGCQHFCLPGQESYTCSCAQGYRLGEDHKQCVPHDQCACGVLTSEK 180
Query: 181 RAPDLQDLPWQVKLTNSEGKDFCGGVIIRENFVLTTAKCSLLHRNITVKTYFNRTSQDPL 240
RAPDLQDLPWQVKLTNSEGKDFCGGVIIRENFVLTTAKCSLLHRNITVKTYFNRTSQDPL
Sbjct: 181 RAPDLQDLPWQVKLTNSEGKDFCGGVIIRENFVLTTAKCSLLHRNITVKTYFNRTSQDPL 240
Query: 241 MIKITHVHVHMRYDADAGENDLSLLELEWPIQCPGAGLPVCTPEKDFAEHLLIPRTRGLL 300
MIKITHVHVHMRYDADAGENDLSLLELEWPIQCPGAGLPVCTPEKDFAEHLLIPRTRGLL
Sbjct: 241 MIKITHVHVHMRYDADAGENDLSLLELEWPIQCPGAGLPVCTPEKDFAEHLLIPRTRGLL 300
Query: 301 SGWARNGTDLGNSLTTRPVTLVEGEECGQVLNVTVTTRTYCERSSVAAMHWMDGSVVTRE 360
SGWARNGTDLGNSLTTRPVTLVEGEECGQVLNVTVTTRTYCERSSVAAMHWMDGSVVTRE
Sbjct: 301 SGWARNGTDLGNSLTTRPVTLVEGEECGQVLNVTVTTRTYCERSSVAAMHWMDGSVVTRE 360
Query: 361 HRGSWFLTGVLGSQPVGGQAHMVLVTKVSRYSLWFKQIMN 400
HRGSWFLTGVLGSQPVGGQAHMVLVTKVSRYSLWFKQIMN
Sbjct: 361 HRGSWFLTGVLGSQPVGGQAHMVLVTKVSRYSLWFKQIMN 400
>gi|4503625 coagulation factor X preproprotein [Homo sapiens]
Length = 488
Score = 191 bits (486), Expect = 8e-49
Identities = 134/448 (29%), Positives = 198/448 (44%), Gaps = 75/448 (16%)
Query: 23 SVFLPASKANDVLVRWKRAGSYLLEELFEGNLEKECYEEICVYEEAREVFENEVVTDEFW 82
S+F+ +AN++L R RA S+L EE+ +G+LE+EC EE C YEEAREVFE+ T+EFW
Sbjct: 23 SLFIRREQANNILARVTRANSFL-EEMKKGHLERECMEETCSYEEAREVFEDSDKTNEFW 81
Query: 83 RRYKGGSPCISQPCLHNGSCQDSIWGYTCTCSPGYEGSNCELAKNECHPERTDGCQHFCL 142
+YK G C + PC + G C+D + YTCTC G+EG NCEL + C FC
Sbjct: 82 NKYKDGDQCETSPCQNQGKCKDGLGEYTCTCLEGFEGKNCELFTRKLCSLDNGDCDQFCH 141
Query: 143 PGQESYTCSCAQGYRLGEDHKQCVPHDQCACGVLTSEKR-------------APDLQDLP 189
Q S CSCA+GY L ++ K C+P CG T E+R APD +
Sbjct: 142 EEQNSVVCSCARGYTLADNGKACIPTGPYPCGKQTLERRKRSVAQATSSSGEAPD--SIT 199
Query: 190 WQV----------------------------KLTNSEGKDFC------------------ 203
W+ LT G C
Sbjct: 200 WKPYDAADLDPTENPFDLLDFNQTQPERGDNNLTRIVGGQECKDGECPWQALLINEENEG 259
Query: 204 --GGVIIRENFVLTTAKCSLLHRNITVKTYFNRTSQDPLMIKITHVHV---HMRYDADAG 258
GG I+ E ++LT A C + V+ T Q+ + V V H R+ +
Sbjct: 260 FCGGTILSEFYILTAAHCLYQAKRFKVRVGDRNTEQEEGGEAVHEVEVVIKHNRFTKETY 319
Query: 259 ENDLSLLELEWPIQCPGAGLPVCTPEKDFAEHLLIPRTRGLLSGWARNGTDLGNS--LTT 316
+ D+++L L+ PI P C PE+D+AE L+ + G++SG+ R S L
Sbjct: 320 DFDIAVLRLKTPITFRMNVAPACLPERDWAESTLMTQKTGIVSGFGRTHEKGRQSTRLKM 379
Query: 317 RPVTLVEGEECGQVLNVTVTTRTYC----ERSSVAAMHWMDGSVVTREHRGSWFLTGVLG 372
V V+ C + +T +C + A G VTR + ++F+TG++
Sbjct: 380 LEVPYVDRNSCKLSSSFIITQNMFCAGYDTKQEDACQGDSGGPHVTR-FKDTYFVTGIVS 438
Query: 373 -SQPVGGQAHMVLVTKVSRYSLWFKQIM 399
+ + + TKV+ + W + M
Sbjct: 439 WGEGCARKGKYGIYTKVTAFLKWIDRSM 466
>gi|4503649 coagulation factor IX preproprotein [Homo sapiens]
Length = 461
Score = 190 bits (482), Expect = 2e-48
Identities = 140/449 (31%), Positives = 200/449 (44%), Gaps = 61/449 (13%)
Query: 6 PLLQGLVLVLALHRVEPSVFLPASKANDVLVRWKRAGSYLLEELFEGNLEKECYEEICVY 65
P L + L+ L E +VFL AN +L R KR S LEE +GNLE+EC EE C +
Sbjct: 12 PGLITICLLGYLLSAECTVFLDHENANKILNRPKRYNSGKLEEFVQGNLERECMEEKCSF 71
Query: 66 EEAREVFENEVVTDEFWRRYKGGSPCISQPCLHNGSCQDSIWGYTCTCSPGYEGSNCELA 125
EEAREVFEN T EFW++Y G C S PCL+ GSC+D I Y C C G+EG NCEL
Sbjct: 72 EEAREVFENTERTTEFWKQYVDGDQCESNPCLNGGSCKDDINSYECWCPFGFEGKNCELD 131
Query: 126 KNECHPERTDGCQHFCLPGQES-YTCSCAQGYRLGEDHKQCVPHDQCACG---------V 175
C+ + C+ FC ++ CSC +GYRL E+ K C P CG +
Sbjct: 132 VT-CN-IKNGRCEQFCKNSADNKVVCSCTEGYRLAENQKSCEPAVPFPCGRVSVSQTSKL 189
Query: 176 LTSEKRAPDLQ------------------------------------DLPWQVKLTNSEG 199
+E PD+ PWQV L N +
Sbjct: 190 TRAETVFPDVDYVNSTEAETILDNITQSTQSFNDFTRVVGGEDAKPGQFPWQVVL-NGKV 248
Query: 200 KDFCGGVIIRENFVLTTAKCSLLHRNITV---KTYFNRTSQDPLMIKITHVHVHMRYDAD 256
FCGG I+ E +++T A C ITV + T + + H Y+A
Sbjct: 249 DAFCGGSIVNEKWIVTAAHCVETGVKITVVAGEHNIEETEHTEQKRNVIRIIPHHNYNAA 308
Query: 257 AGE--NDLSLLELEWPIQCPGAGLPVCTPEKDFAEHLLIPRTRGLLSGWARNGTDLGNSL 314
+ +D++LLEL+ P+ P+C +K++ ++ + G +SGW R ++L
Sbjct: 309 INKYNHDIALLELDEPLVLNSYVTPICIADKEYT-NIFLKFGSGYVSGWGRVFHKGRSAL 367
Query: 315 TTR--PVTLVEGEECGQVLNVTVTTRTYC---ERSSVAAMHWMDGSVVTREHRGSWFLTG 369
+ V LV+ C + T+ +C + G E G+ FLTG
Sbjct: 368 VLQYLRVPLVDRATCLRSTKFTIYNNMFCAGFHEGGRDSCQGDSGGPHVTEVEGTSFLTG 427
Query: 370 VLG-SQPVGGQAHMVLVTKVSRYSLWFKQ 397
++ + + + TKVSRY W K+
Sbjct: 428 IISWGEECAMKGKYGIYTKVSRYVNWIKE 456
>gi|4506115 protein C [Homo sapiens]
Length = 461
Score = 178 bits (452), Expect = 7e-45
Identities = 135/425 (31%), Positives = 193/425 (45%), Gaps = 58/425 (13%)
Query: 23 SVFLPASKANDVLVRWKRAGSYLLEELFEGNLEKECYEEICVYEEAREVFENEVVTDEFW 82
SVF + +A+ VL KRA S+L EEL +LE+EC EEIC +EEA+E+F+N T FW
Sbjct: 25 SVFSSSERAHQVLRIRKRANSFL-EELRHSSLERECIEEICDFEEAKEIFQNVDDTLAFW 83
Query: 83 RRYKGGSPCISQP--------CLHNGSCQDSIWGYTCTCSPGYEGSNC--ELAKNECHPE 132
++ G C+ P C +G+C D I ++C C G+EG C E++ C +
Sbjct: 84 SKHVDGDQCLVLPLEHPCASLCCGHGTCIDGIGSFSCDCRSGWEGRFCQREVSFLNCSLD 143
Query: 133 RTDGCQHFCLPGQESYTCSCAQGYRLGEDHKQCVPHDQCACG--VLTSEKRAPDLQ---- 186
GC H+CL CSCA GY+LG+D QC P + CG EK+ L+
Sbjct: 144 -NGGCTHYCLEEVGWRRCSCAPGYKLGDDLLQCHPAVKFPCGRPWKRMEKKRSHLKRDTE 202
Query: 187 -------------------DLPWQVKLTNSEGKDFCGGVIIRENFVLTTAKCSLLHRNIT 227
D PWQV L +S+ K CG V+I ++VLT A C + +
Sbjct: 203 DQEDQVDPRLIDGKMTRRGDSPWQVVLLDSKKKLACGAVLIHPSWVLTAAHCMDESKKLL 262
Query: 228 VKT---YFNRTSQDPLMIKITHVHVHMRYDADAGENDLSLLELEWPIQCPGAGLPVCTPE 284
V+ R + L + I V VH Y +ND++LL L P +P+C P+
Sbjct: 263 VRLGEYDLRRWEKWELDLDIKEVFVHPNYSKSTTDNDIALLHLAQPATLSQTIVPICLPD 322
Query: 285 KDFAEHLLIPR-TRGLLSGWA----------RNGTDLGNSLTTRPVTLVEGEECGQVLNV 333
AE L L++GW RN T + N + + +V EC +V++
Sbjct: 323 SGLAERELNQAGQETLVTGWGYHSSREKEAKRNRTFVLNFI---KIPVVPHNECSEVMSN 379
Query: 334 TVTTRTYCE---RSSVAAMHWMDGSVVTREHRGSWFLTGVLGSQPVGGQAHMV-LVTKVS 389
V+ C A G + G+WFL G++ G H + TKVS
Sbjct: 380 MVSENMLCAGILGDRQDACEGDSGGPMVASFHGTWFLVGLVSWGEGCGLLHNYGVYTKVS 439
Query: 390 RYSLW 394
RY W
Sbjct: 440 RYLDW 444
>gi|10518503 coagulation factor VII isoform b precursor [Homo
sapiens]
Length = 444
Score = 176 bits (447), Expect = 3e-44
Identities = 131/428 (30%), Positives = 197/428 (46%), Gaps = 40/428 (9%)
Query: 8 LQGLVLVLALHRVEPSVFLPASKANDVLVRWKRAGSYLLEELFEGNLEKECYEEICVYEE 67
L+ L L+L L +VF+ +A+ VL R +RA ++L EEL G+LE+EC EE C +EE
Sbjct: 6 LRLLCLLLGLQGCLAAVFVTQEEAHGVLHRRRRANAFL-EELRPGSLERECKEEQCSFEE 64
Query: 68 AREVFENEVVTDEFWRRYKGGSPCISQPCLHNGSCQDSIWGYTCTCSPGYEGSNCELAKN 127
ARE+F++ T FW Y G C S PC + GSC+D + Y C C P +EG NCE K+
Sbjct: 65 AREIFKDAERTKLFWISYSDGDQCASSPCQNGGSCKDQLQSYICFCLPAFEGRNCETHKD 124
Query: 128 E---CHPERTDGCQHFCLPGQ-ESYTCSCAQGYRLGEDHKQCVPHDQCACG-VLTSEKRA 182
+ C E GC+ +C +C C +GY L D C P + CG + EKR
Sbjct: 125 DQLICVNE-NGGCEQYCSDHTGTKRSCRCHEGYSLLADGVSCTPTVEYPCGKIPILEKRN 183
Query: 183 PDLQ-------------DLPWQVKLTNSEGKDFCGGVIIRENFVLTTAKCSLLHRN---- 225
+ PWQV L G CGG +I +V++ A C +N
Sbjct: 184 ASKPQGRIVGGKVCPKGECPWQVLLL-VNGAQLCGGTLINTIWVVSAAHCFDKIKNWRNL 242
Query: 226 --ITVKTYFNRTSQDPLMIKITHVHVHMRYDADAGENDLSLLELEWPIQCPGAGLPVCTP 283
+ + + D ++ V + Y +D++LL L P+ +P+C P
Sbjct: 243 IAVLGEHDLSEHDGDEQSRRVAQVIIPSTYVPGTTNHDIALLRLHQPVVLTDHVVPLCLP 302
Query: 284 EKDFAEHLLIPRTRGLLSGWA----RNGTDLGNSLTTRP-----VTLVEGEECGQVLNVT 334
E+ F+E L L+SGW R T L + P L + + G N+T
Sbjct: 303 ERTFSERTLAFVRFSLVSGWGQLLDRGATALELMVLNVPRLMTQDCLQQSRKVGDSPNIT 362
Query: 335 --VTTRTYCERSSVAAMHWMDGSVVTREHRGSWFLTGVLG-SQPVGGQAHMVLVTKVSRY 391
+ Y + S + G T +RG+W+LTG++ Q H + T+VS+Y
Sbjct: 363 EYMFCAGYSDGSKDSCKGDSGGPHAT-HYRGTWYLTGIVSWGQGCATVGHFGVYTRVSQY 421
Query: 392 SLWFKQIM 399
W +++M
Sbjct: 422 IEWLQKLM 429
>gi|4503645 coagulation factor VII isoform a precursor [Homo
sapiens]
Length = 466
Score = 172 bits (436), Expect = 5e-43
Identities = 126/412 (30%), Positives = 189/412 (45%), Gaps = 40/412 (9%)
Query: 24 VFLPASKANDVLVRWKRAGSYLLEELFEGNLEKECYEEICVYEEAREVFENEVVTDEFWR 83
VF+ +A+ VL R +RA ++L EEL G+LE+EC EE C +EEARE+F++ T FW
Sbjct: 44 VFVTQEEAHGVLHRRRRANAFL-EELRPGSLERECKEEQCSFEEAREIFKDAERTKLFWI 102
Query: 84 RYKGGSPCISQPCLHNGSCQDSIWGYTCTCSPGYEGSNCELAKNE---CHPERTDGCQHF 140
Y G C S PC + GSC+D + Y C C P +EG NCE K++ C E GC+ +
Sbjct: 103 SYSDGDQCASSPCQNGGSCKDQLQSYICFCLPAFEGRNCETHKDDQLICVNE-NGGCEQY 161
Query: 141 CLPGQ-ESYTCSCAQGYRLGEDHKQCVPHDQCACG-VLTSEKRAPDLQ------------ 186
C +C C +GY L D C P + CG + EKR
Sbjct: 162 CSDHTGTKRSCRCHEGYSLLADGVSCTPTVEYPCGKIPILEKRNASKPQGRIVGGKVCPK 221
Query: 187 -DLPWQVKLTNSEGKDFCGGVIIRENFVLTTAKCSLLHRN------ITVKTYFNRTSQDP 239
+ PWQV L G CGG +I +V++ A C +N + + + D
Sbjct: 222 GECPWQVLLL-VNGAQLCGGTLINTIWVVSAAHCFDKIKNWRNLIAVLGEHDLSEHDGDE 280
Query: 240 LMIKITHVHVHMRYDADAGENDLSLLELEWPIQCPGAGLPVCTPEKDFAEHLLIPRTRGL 299
++ V + Y +D++LL L P+ +P+C PE+ F+E L L
Sbjct: 281 QSRRVAQVIIPSTYVPGTTNHDIALLRLHQPVVLTDHVVPLCLPERTFSERTLAFVRFSL 340
Query: 300 LSGWA----RNGTDLGNSLTTRP-----VTLVEGEECGQVLNVT--VTTRTYCERSSVAA 348
+SGW R T L + P L + + G N+T + Y + S +
Sbjct: 341 VSGWGQLLDRGATALELMVLNVPRLMTQDCLQQSRKVGDSPNITEYMFCAGYSDGSKDSC 400
Query: 349 MHWMDGSVVTREHRGSWFLTGVLG-SQPVGGQAHMVLVTKVSRYSLWFKQIM 399
G T +RG+W+LTG++ Q H + T+VS+Y W +++M
Sbjct: 401 KGDSGGPHAT-HYRGTWYLTGIVSWGQGCATVGHFGVYTRVSQYIEWLQKLM 451
>gi|192447438 protein S, alpha preproprotein [Homo sapiens]
Length = 676
Score = 117 bits (293), Expect = 2e-26
Identities = 77/203 (37%), Positives = 99/203 (48%), Gaps = 38/203 (18%)
Query: 4 CVPLLQGLVLVLALHRVEPSVFLPASKANDVLVRWKRAGSYLLEELFEGNLEKECYEEIC 63
C LL L+LVL V + FL +A+ VLVR +RA S LLEE +GNLE+EC EE+C
Sbjct: 8 CGALLACLLLVLP---VSEANFLSKQQASQVLVRKRRANS-LLEETKQGNLERECIEELC 63
Query: 64 VYEEAREVFENEVVTDEFW-------RRYKGG-----------------------SPCIS 93
EEAREVFEN+ TD F+ R ++ G C
Sbjct: 64 NKEEAREVFENDPETDYFYPKYLVCLRSFQTGLFTAARQSTNAYPDLRSCVNAIPDQCSP 123
Query: 94 QPCLHNG--SCQDSIWGYTCTCSPGYEGSNCELAKNECHPER--TDGCQHFCLPGQESYT 149
PC +G SC+D +TCTC PG++G CE NEC GC C SY
Sbjct: 124 LPCNEDGYMSCKDGKASFTCTCKPGWQGEKCEFDINECKDPSNINGGCSQICDNTPGSYH 183
Query: 150 CSCAQGYRLGEDHKQCVPHDQCA 172
CSC G+ + + K C D+C+
Sbjct: 184 CSCKNGFVMLSNKKDCKDVDECS 206
Score = 34.3 bits (77), Expect = 0.20
Identities = 20/70 (28%), Positives = 31/70 (44%), Gaps = 10/70 (14%)
Query: 102 CQDSIWGYTCTCSPGY----EGSNCELAKNECHPERTDGCQHFCLPGQESYTCSC--AQG 155
C++ + C C GY + +CE +EC C C+ YTC C +G
Sbjct: 217 CKNIPGDFECECPEGYRYNLKSKSCEDI-DECSENM---CAQLCVNYPGGYTCYCDGKKG 272
Query: 156 YRLGEDHKQC 165
++L +D K C
Sbjct: 273 FKLAQDQKSC 282
>gi|4557617 growth arrest-specific 6 isoform 1 precursor [Homo
sapiens]
Length = 678
Score = 112 bits (279), Expect = 8e-25
Identities = 70/199 (35%), Positives = 92/199 (46%), Gaps = 25/199 (12%)
Query: 11 LVLVLALHRVEPSVFLPASKANDVLVRWKRAGSYLLEELFEGNLEKECYEEICVYEEARE 70
L+L+L + LPA +A L +R + EE +G+LE+EC EE+C EEARE
Sbjct: 18 LLLLLLAAECALAALLPAREATQFLRPRQRRAFQVFEEAKQGHLERECVEELCSREEARE 77
Query: 71 VFENEVVTDEFWRRY-----KGGSP-----------------CISQPCLHNG--SCQDSI 106
VFEN+ TD F+ RY K GSP C PC G +CQD +
Sbjct: 78 VFENDPETDYFYPRYLDCINKYGSPYTKNSGFATCVQNLPDQCTPNPCDRKGTQACQDLM 137
Query: 107 WGYTCTCSPGYEGSNCELAKNECHPERTDGCQHFCLPGQESYTCSCAQGYRLGEDHKQCV 166
+ C C G+ G C+ NEC E GC C S+ CSC G+ L D + C
Sbjct: 138 GNFFCLCKAGWGGRLCDKDVNECSQE-NGGCLQICHNKPGSFHCSCHSGFELSSDGRTCQ 196
Query: 167 PHDQCACGVLTSEKRAPDL 185
D+CA E R +L
Sbjct: 197 DIDECADSEACGEARCKNL 215
Score = 38.1 bits (87), Expect = 0.014
Identities = 20/77 (25%), Positives = 30/77 (38%), Gaps = 2/77 (2%)
Query: 91 CISQPCLHNGSCQDSIWGYTCTCSPGYEGSNCELAKNECHPERTDGCQHFCLPGQESYTC 150
C C++ Y+C C G+ S+ E A + C+ C+ SYTC
Sbjct: 201 CADSEACGEARCKNLPGSYSCLCDEGFAYSSQEKACRDVDECLQGRCEQVCVNSPGSYTC 260
Query: 151 SC--AQGYRLGEDHKQC 165
C G +L +D C
Sbjct: 261 HCDGRGGLKLSQDMDTC 277
>gi|23957702 transmembrane protease, serine 6 [Homo sapiens]
Length = 811
Score = 87.0 bits (214), Expect = 3e-17
Identities = 82/331 (24%), Positives = 134/331 (40%), Gaps = 52/331 (15%)
Query: 91 CISQPCLHNGS----CQDSI--WGYTCTCSPGYEGSNCELAKNECHPERTDGCQHFCLPG 144
C QP NGS CQ+ + +T C E +C N R D C G
Sbjct: 510 CDGQPDCLNGSDEEQCQEGVPCGTFTFQC----EDRSCVKKPNPQCDGRPD-----CRDG 560
Query: 145 QESYTCSCA-QGYRLGEDHKQCVPHDQCACGVLTSEKRAPDLQDLPWQVKLTNSEGKDFC 203
+ C C QG P + G ++SE + PWQ L G+ C
Sbjct: 561 SDEEHCDCGLQG-----------PSSRIVGGAVSSEG------EWPWQASL-QVRGRHIC 602
Query: 204 GGVIIRENFVLTTAKC--------SLLHRNITVKTYFNRTSQDPLMIKITHVHVHMRYDA 255
GG +I + +V+T A C ++L K + N + K++ + +H ++
Sbjct: 603 GGALIADRWVITAAHCFQEDSMASTVLWTVFLGKVWQNSRWPGEVSFKVSRLLLHPYHEE 662
Query: 256 DAGENDLSLLELEWPIQCPGAGLPVCTPEKDFAEHLLIPRTRGLLSGWA--RNGTDLGNS 313
D+ + D++LL+L+ P+ A PVC P + H P ++GW R G + N+
Sbjct: 663 DSHDYDVALLQLDHPVVRSAAVRPVCLPAR---SHFFEPGLHCWITGWGALREGGPISNA 719
Query: 314 LTTRPVTLVEGEECGQVLNVTVTTRTYC----ERSSVAAMHWMDGSVVTREHRGSWFLTG 369
L V L+ + C +V VT R C + A G +V + G WFL G
Sbjct: 720 LQKVDVQLIPQDLCSEVYRYQVTPRMLCAGYRKGKKDACQGDSGGPLVCKALSGRWFLAG 779
Query: 370 VLG-SQPVGGQAHMVLVTKVSRYSLWFKQIM 399
++ G + + T+++ W +Q++
Sbjct: 780 LVSWGLGCGRPNYFGVYTRITGVISWIQQVV 810
>gi|122937283 6720455I24Rik homolog [Homo sapiens]
Length = 1413
Score = 79.3 bits (194), Expect = 6e-15
Identities = 38/69 (55%), Positives = 47/69 (68%), Gaps = 7/69 (10%)
Query: 91 CISQPCLHNGSCQDSIWGYTCTCSPGYEGSNCELAKNEC--HPERTDG-CQHFCLPGQES 147
C SQPCLH GSCQD + GY C CS GYEG++CEL ++EC HP R G C++ LPG +
Sbjct: 757 CRSQPCLHGGSCQDRVAGYLCLCSTGYEGAHCELERDECRAHPCRNGGSCRN--LPG--A 812
Query: 148 YTCSCAQGY 156
Y C C G+
Sbjct: 813 YVCRCPAGF 821
Score = 58.5 bits (140), Expect = 1e-08
Identities = 30/92 (32%), Positives = 43/92 (46%), Gaps = 17/92 (18%)
Query: 91 CISQPCLHNGSCQDSIWGYTCTCSPGYEGSNCELAKN---------ECHPERTDGCQHFC 141
C PCL+ GSC D + YTC C+ ++G CE + CH T C
Sbjct: 391 CSPDPCLNGGSCVDLVGNYTCLCAEPFKGLRCETGDHPVPDACLSAPCHNGGT------C 444
Query: 142 LPGQESYTCSCAQGYRLGEDHKQCVPHDQCAC 173
+ + Y C C +G+ +G D ++ VP D C C
Sbjct: 445 VDADQGYVCECPEGF-MGLDCRERVP-DDCEC 474
Score = 55.1 bits (131), Expect = 1e-07
Identities = 32/88 (36%), Positives = 40/88 (45%), Gaps = 6/88 (6%)
Query: 89 SPCISQPCLHNGSCQDSIWGYTCTCSPGYEGSNCELAKNECHPERTDGCQH--FCLPGQE 146
SPC S PC + GSC YTC C G+ G +CE A+ H + C++ C
Sbjct: 543 SPCDSDPCFNGGSCDAHDDSYTCECPRGFHGKHCEKARP--HLCSSGPCRNGGTCKEAGG 600
Query: 147 SYTCSCAQGYRLGEDHKQCVPHDQCACG 174
Y CSC YR H + D CA G
Sbjct: 601 EYHCSCP--YRFTGRHCEIGKPDSCASG 626
Score = 55.1 bits (131), Expect = 1e-07
Identities = 25/71 (35%), Positives = 34/71 (47%), Gaps = 2/71 (2%)
Query: 91 CISQPCLHNGSCQDSIWGYTCTCSPGYEGSNCELAKNECHPERTDGCQHFCLPGQESYTC 150
C S PC H G C+ Y C C + G +CE + C G + +CL S++C
Sbjct: 833 CDSSPCQHGGRCESGGGAYLCVCPESFFGYHCETVSDPCFSSPCGG-RGYCLASNGSHSC 891
Query: 151 SCAQGYRLGED 161
+C GY GED
Sbjct: 892 TCKVGY-TGED 901
Score = 54.3 bits (129), Expect = 2e-07
Identities = 25/71 (35%), Positives = 37/71 (52%), Gaps = 5/71 (7%)
Query: 89 SPCISQPCLHNGSCQDSIWGYTCTCSPGYEGSNCELAKNECHPERTDGCQH--FCLPGQE 146
SPC ++ C H G CQ C C GY G+ CE+ ++C P D C + C+
Sbjct: 351 SPCDTKECQHGGQCQVENGSAVCVCQAGYTGAACEMDVDDCSP---DPCLNGGSCVDLVG 407
Query: 147 SYTCSCAQGYR 157
+YTC CA+ ++
Sbjct: 408 NYTCLCAEPFK 418
Score = 52.8 bits (125), Expect = 6e-07
Identities = 26/68 (38%), Positives = 32/68 (47%), Gaps = 5/68 (7%)
Query: 91 CISQPCLHNGSCQDSIWGYTCTCSPGYEGSNCELAKNECHPERTDGCQH--FCLPGQESY 148
C SQPC + G+C I + C C G+ G CE A++ C T CQH C S
Sbjct: 315 CASQPCQNGGTCTHGINSFRCQCPAGFGGPTCETAQSPCD---TKECQHGGQCQVENGSA 371
Query: 149 TCSCAQGY 156
C C GY
Sbjct: 372 VCVCQAGY 379
Score = 50.8 bits (120), Expect = 2e-06
Identities = 33/98 (33%), Positives = 46/98 (46%), Gaps = 18/98 (18%)
Query: 89 SPCIS-QPCLHNGSC-QDSIWG---YTCTCSPGYEGSNCELAKNECHPERTDGCQH--FC 141
S C++ +PCL+ G C D + G YTC+C G+ G C L NEC + CQ+ C
Sbjct: 270 SVCLALRPCLNGGKCIDDCVTGNPSYTCSCLSGFTGRRCHLDVNEC---ASQPCQNGGTC 326
Query: 142 LPGQESYTCSCAQGY--------RLGEDHKQCVPHDQC 171
G S+ C C G+ + D K+C QC
Sbjct: 327 THGINSFRCQCPAGFGGPTCETAQSPCDTKECQHGGQC 364
Score = 48.1 bits (113), Expect = 1e-05
Identities = 24/68 (35%), Positives = 31/68 (45%), Gaps = 5/68 (7%)
Query: 91 CISQPCLHNGSCQDSIWGYTCTCSPGYEGSNCELAKNEC--HPERTDGCQHFCLPGQESY 148
C S PC + G+C I Y C C PG+ G +CE+A + C P G C +
Sbjct: 623 CASGPCHNGGTCFHYIGKYKCDCPPGFSGRHCEIAPSPCFRSPCVNGGT---CEDRDTDF 679
Query: 149 TCSCAQGY 156
C C GY
Sbjct: 680 FCHCQAGY 687
Score = 48.1 bits (113), Expect = 1e-05
Identities = 22/68 (32%), Positives = 33/68 (48%), Gaps = 5/68 (7%)
Query: 91 CISQPCLHNGSCQDSIWGYTCTCSPGYEGSNCELAKNECHPERTDGCQH--FCLPGQESY 148
C + PC + GSC++ Y C C G+ G +CE + C + CQH C G +Y
Sbjct: 795 CRAHPCRNGGSCRNLPGAYVCRCPAGFVGVHCETEVDACD---SSPCQHGGRCESGGGAY 851
Query: 149 TCSCAQGY 156
C C + +
Sbjct: 852 LCVCPESF 859
Score = 44.3 bits (103), Expect = 2e-04
Identities = 17/43 (39%), Positives = 25/43 (58%), Gaps = 1/43 (2%)
Query: 89 SPCISQPCLHNGSCQDSIWGYTCTCSPGYEGSNCELAKNECHP 131
SPC PC++ G+C+D + C C GY G C+ A+ +C P
Sbjct: 659 SPCFRSPCVNGGTCEDRDTDFFCHCQAGYMGRRCQ-AEVDCGP 700
Score = 40.8 bits (94), Expect = 0.002
Identities = 21/61 (34%), Positives = 28/61 (45%), Gaps = 10/61 (16%)
Query: 62 ICVYEEAREVFENEVVTDEFWRRYKGGSPCISQPCLHNGSCQDSIWGYTCTCSPGYEGSN 121
+CV E+ + E V+D PC S PC G C S ++CTC GY G +
Sbjct: 852 LCVCPESFFGYHCETVSD----------PCFSSPCGGRGYCLASNGSHSCTCKVGYTGED 901
Query: 122 C 122
C
Sbjct: 902 C 902
Score = 40.8 bits (94), Expect = 0.002
Identities = 14/35 (40%), Positives = 20/35 (57%)
Query: 91 CISQPCLHNGSCQDSIWGYTCTCSPGYEGSNCELA 125
C PC + G+C ++C C PG++G CELA
Sbjct: 1311 CSENPCQNGGTCVPGADAHSCDCGPGFKGRRCELA 1345
Score = 34.7 bits (78), Expect = 0.16
Identities = 23/86 (26%), Positives = 37/86 (43%), Gaps = 6/86 (6%)
Query: 90 PC-ISQPCLHNGSCQDSIWGYTCTCSPGYEGSNCELAKNECHPERTDGCQHFCLPGQESY 148
PC ++ C G C + Y C C + S+ + + P G C +SY
Sbjct: 507 PCNMNTQCPDGGYCMEHGGSYLCVCHTDHNASHSLPSPCDSDPCFNGGS---CDAHDDSY 563
Query: 149 TCSCAQGYRLGEDHKQCVPHDQCACG 174
TC C +G+ G+ ++ PH C+ G
Sbjct: 564 TCECPRGFH-GKHCEKARPH-LCSSG 587
>gi|4503137 chymotrypsin-like [Homo sapiens]
Length = 264
Score = 75.1 bits (183), Expect = 1e-13
Identities = 62/221 (28%), Positives = 109/221 (49%), Gaps = 15/221 (6%)
Query: 189 PWQVKLTNSEGKDFCGGVIIRENFVLTTAKCSLL-HRNITVKTYFNRTSQ-DPL-MIKIT 245
PWQV L +S G FCGG +I +++V+T A C++ R+ V ++R+S +PL ++ ++
Sbjct: 46 PWQVSLQDSSGFHFCGGSLISQSWVVTAAHCNVSPGRHFVVLGEYDRSSNAEPLQVLSVS 105
Query: 246 HVHVHMRYDADAGENDLSLLELEWPIQCPGAGLPVCTPEKDFAEHLLIPRTRGLLSGWAR 305
H +++ ND++LL+L P Q PVC + A L + +GW R
Sbjct: 106 RAITHPSWNSTTMNNDVTLLKLASPAQYTTRISPVCLASSNEA---LTEGLTCVTTGWGR 162
Query: 306 NGTDLGN----SLTTRPVTLVEGEECGQVLNVTVTTRTYCERSSVAAMHWMD-GSVVTRE 360
+ +GN L + LV +C Q ++T C + A+ D G + +
Sbjct: 163 L-SGVGNVTPAHLQQVALPLVTVNQCRQYWGSSITDSMICAGGAGASSCQGDSGGPLVCQ 221
Query: 361 HRGSWFLTGVL--GSQPVGGQAHMVLVTKVSRYSLWFKQIM 399
+W L G++ G++ +A V T+VS++S W Q++
Sbjct: 222 KGNTWVLIGIVSWGTKNCNVRAPAV-YTRVSKFSTWINQVI 261
>gi|31543811 proline rich Gla (G-carboxyglutamic acid) 3
(transmembrane) [Homo sapiens]
Length = 231
Score = 71.6 bits (174), Expect = 1e-12
Identities = 36/73 (49%), Positives = 47/73 (64%), Gaps = 1/73 (1%)
Query: 23 SVFLPASKANDVLVRWKRAGSYLLEELFEGNLEKECYEEICVYEEAREVFENEVVTDEFW 82
+VFL A A+ VL R+ RA +L EEL +G +E+EC EEIC YEE +EVFEN+ T EFW
Sbjct: 2 AVFLEAKDAHSVLKRFPRANEFL-EELRQGTIERECMEEICSYEEVKEVFENKEKTMEFW 60
Query: 83 RRYKGGSPCISQP 95
+ Y + P
Sbjct: 61 KGYPNAVYSVRDP 73
>gi|215422383 proline rich Gla (G-carboxyglutamic acid) 1 [Homo
sapiens]
Length = 218
Score = 71.2 bits (173), Expect = 2e-12
Identities = 33/62 (53%), Positives = 41/62 (66%), Gaps = 1/62 (1%)
Query: 24 VFLPASKANDVLVRWKRAGSYLLEELFEGNLEKECYEEICVYEEAREVFENEVVTDEFWR 83
VFL KAN +L R+ RA + EE+ +GN+E+EC EE C +EEARE FEN T EFW
Sbjct: 4 VFLTGEKANSILKRYPRANGFF-EEIRQGNIERECKEEFCTFEEAREAFENNEKTKEFWS 62
Query: 84 RY 85
Y
Sbjct: 63 TY 64
>gi|4506135 proline rich Gla (G-carboxyglutamic acid) 1 [Homo
sapiens]
Length = 218
Score = 71.2 bits (173), Expect = 2e-12
Identities = 33/62 (53%), Positives = 41/62 (66%), Gaps = 1/62 (1%)
Query: 24 VFLPASKANDVLVRWKRAGSYLLEELFEGNLEKECYEEICVYEEAREVFENEVVTDEFWR 83
VFL KAN +L R+ RA + EE+ +GN+E+EC EE C +EEARE FEN T EFW
Sbjct: 4 VFLTGEKANSILKRYPRANGFF-EEIRQGNIERECKEEFCTFEEAREAFENNEKTKEFWS 62
Query: 84 RY 85
Y
Sbjct: 63 TY 64
>gi|189491647 fibulin 7 isoform 2 [Homo sapiens]
Length = 393
Score = 70.5 bits (171), Expect = 3e-12
Identities = 35/94 (37%), Positives = 46/94 (48%), Gaps = 8/94 (8%)
Query: 86 KGGSPCISQPCLHNGSCQDSIWGYTCTCSPGYEGSNC----ELAKNECHPERTDG----C 137
+G S C SQPC + G+C + + Y C C PG G+ C + NEC +G C
Sbjct: 135 RGISECSSQPCQNGGTCVEGVNQYRCICPPGRTGNRCQHQAQTDVNECELYGQEGRPRLC 194
Query: 138 QHFCLPGQESYTCSCAQGYRLGEDHKQCVPHDQC 171
H C+ SY C+C GYR D K C D+C
Sbjct: 195 MHACVNTPGSYRCTCPGGYRTLADGKSCEDVDEC 228
>gi|118498350 chymotrypsin B2 [Homo sapiens]
Length = 263
Score = 69.3 bits (168), Expect = 6e-12
Identities = 57/221 (25%), Positives = 98/221 (44%), Gaps = 16/221 (7%)
Query: 189 PWQVKLTNSEGKDFCGGVIIRENFVLTTAKCSLLHRNITVKTYFNRTSQDP--LMIKITH 246
PWQV L + G FCGG +I E++V+T A C + ++ V F++ S + ++KI
Sbjct: 46 PWQVSLQDKTGFHFCGGSLISEDWVVTAAHCGVRTSDVVVAGEFDQGSDEENIQVLKIAK 105
Query: 247 VHVHMRYDADAGENDLSLLELEWPIQCPGAGLPVCTP--EKDFAEHLLIPRTRGLLSGWA 304
V + ++ ND++LL+L P + VC P + DF L T GW
Sbjct: 106 VFKNPKFSILTVNNDITLLKLATPARFSQTVSAVCLPSADDDFPAGTLCATT-----GWG 160
Query: 305 R---NGTDLGNSLTTRPVTLVEGEECGQVLNVTVTTRTYCE-RSSVAAMHWMDGSVVTRE 360
+ N + L + L+ EC + +T C S V++ G + +
Sbjct: 161 KTKYNANKTPDKLQQAALPLLSNAECKKSWGRRITDVMICAGASGVSSCMGDSGGPLVCQ 220
Query: 361 HRGSWFLTGVL--GSQPVGGQAHMVLVTKVSRYSLWFKQIM 399
G+W L G++ GS+ V +V++ W ++I+
Sbjct: 221 KDGAWTLVGIVSWGSRTCSTTTPAV-YARVAKLIPWVQKIL 260
>gi|118498341 chymotrypsin B1 [Homo sapiens]
Length = 263
Score = 68.9 bits (167), Expect = 7e-12
Identities = 57/221 (25%), Positives = 98/221 (44%), Gaps = 16/221 (7%)
Query: 189 PWQVKLTNSEGKDFCGGVIIRENFVLTTAKCSLLHRNITVKTYFNRTSQDP--LMIKITH 246
PWQV L + G FCGG +I E++V+T A C + ++ V F++ S + ++KI
Sbjct: 46 PWQVSLQDKTGFHFCGGSLISEDWVVTAAHCGVRTSDVVVAGEFDQGSDEENIQVLKIAK 105
Query: 247 VHVHMRYDADAGENDLSLLELEWPIQCPGAGLPVCTP--EKDFAEHLLIPRTRGLLSGWA 304
V + ++ ND++LL+L P + VC P + DF L T GW
Sbjct: 106 VFKNPKFSILTVNNDITLLKLATPARFSQTVSAVCLPSADDDFPAGTLCATT-----GWG 160
Query: 305 R---NGTDLGNSLTTRPVTLVEGEECGQVLNVTVTTRTYCE-RSSVAAMHWMDGSVVTRE 360
+ N + L + L+ EC + +T C S V++ G + +
Sbjct: 161 KTKYNANKTPDKLQQAALPLLSNAECKKSWGRRITDVMICAGASGVSSCMGDSGGPLVCQ 220
Query: 361 HRGSWFLTGVL--GSQPVGGQAHMVLVTKVSRYSLWFKQIM 399
G+W L G++ GS + V +V++ W ++I+
Sbjct: 221 KDGAWTLVGIVSWGSDTCSTSSPGV-YARVTKLIPWVQKIL 260
>gi|87196600 polyserase 3 [Homo sapiens]
Length = 553
Score = 68.6 bits (166), Expect = 1e-11
Identities = 67/244 (27%), Positives = 104/244 (42%), Gaps = 24/244 (9%)
Query: 169 DQC-ACGVL-TSEKRAPDLQDLPWQVKLTNSEGKDFCGGVIIRENFVLTTAKCSLLHRNI 226
D C ACG L T+ +A PW+ +L + +G+ CGG ++ E VLT A C + +
Sbjct: 291 DSCVACGSLRTAGPQAGAPSPWPWEARLMH-QGQLACGGALVSEEAVLTAAHCFIGRQ-- 347
Query: 227 TVKTYFNRTSQDPLMIKITHVHVHMRYDADAGENDLSLLELEWPIQCPGAGLPVCTPEKD 286
+ + P + + +H Y G D++LL L P+ + P+C P
Sbjct: 348 APEEWSVGLGTRPEEWGLKQLILHGAYTHPEGGYDMALLLLAQPVTLGASLRPLCLP--- 404
Query: 287 FAEHLLIPRTRGLLSGWARNGTDLGNSLTTRPVTLVEGEECGQ-----------VLNVTV 335
+ +H L RG + G AR G + +SL T PVTL+ C + +L V
Sbjct: 405 YPDHHLPDGERGWVLGRARPGAGI-SSLQTVPVTLLGPRACSRLHAAPGGDGSPILPGMV 463
Query: 336 TTRTYCERSSVAAMHWMDGSVVTREHRGSWFLTGVLG-SQPVGGQAHMVLVTKVSRYSLW 394
T E S + G+ + E RG+WFL G+ G A + T + Y W
Sbjct: 464 CTSAVGELPSCEG---LSGAPLVHEVRGTWFLAGLHSFGDACQGPARPAVFTALPAYEDW 520
Query: 395 FKQI 398
+
Sbjct: 521 VSSL 524
Score = 34.3 bits (77), Expect = 0.20
Identities = 33/152 (21%), Positives = 60/152 (39%), Gaps = 16/152 (10%)
Query: 189 PWQVKLTNSEGKDFCGGVIIRENFVLTTAKC------SLLHRNITVKTYFNRTSQDP--L 240
PWQ + +G C G ++ + +VLT A C + L+ V R P
Sbjct: 49 PWQASVRR-QGAHICSGSLVADTWVLTAAHCFEKAAATELNSWSVVLGSLQREGLSPGAE 107
Query: 241 MIKITHVHVHMRYDADAGENDLSLLELEWPIQCPGAGLPVCTPEKDFAEHLLIPRTRGLL 300
+ + + + Y+ + +DL+LL+L P P+C P+ H
Sbjct: 108 EVGVAALQLPRAYNHYSQGSDLALLQLAHPT----THTPLCLPQ---PAHRFPFGASCWA 160
Query: 301 SGWARNGTDLGNSLTTRPVTLVEGEECGQVLN 332
+GW ++ +D +L + L+ C + N
Sbjct: 161 TGWDQDTSDAPGTLRNLRLRLISRPTCNCIYN 192
>gi|134244285 Notch homolog 3 [Homo sapiens]
Length = 2321
Score = 67.8 bits (164), Expect = 2e-11
Identities = 30/68 (44%), Positives = 38/68 (55%), Gaps = 5/68 (7%)
Query: 90 PCISQPCLHNGSCQDSIWGYTCTCSPGYEGSNCELAKNECHPERTDGCQH--FCLPGQES 147
PC++QPC H G+C+ + GY C C PGY G NCE +EC + CQH C+
Sbjct: 1087 PCLAQPCQHGGTCRGYMGGYMCECLPGYNGDNCEDDVDEC---ASQPCQHGGSCIDLVAR 1143
Query: 148 YTCSCAQG 155
Y CSC G
Sbjct: 1144 YLCSCPPG 1151
Score = 62.0 bits (149), Expect = 9e-10
Identities = 30/94 (31%), Positives = 49/94 (52%), Gaps = 12/94 (12%)
Query: 91 CISQPCLHNGSCQDSIWGYTCTCSPGYEGSNCELAKNECHPERTDGCQH--FCLPGQESY 148
C S PC++ G C+D + G++CTC G+ GS C+L +EC + C++ C+ + Y
Sbjct: 473 CQSSPCVNGGVCKDRVNGFSCTCPSGFSGSTCQLDVDEC---ASTPCRNGAKCVDQPDGY 529
Query: 149 TCSCAQGYR---LGEDHKQCVP----HDQCACGV 175
C CA+G+ + C P H +C G+
Sbjct: 530 ECRCAEGFEGTLCDRNVDDCSPDPCHHGRCVDGI 563
Score = 61.6 bits (148), Expect = 1e-09
Identities = 27/67 (40%), Positives = 38/67 (56%), Gaps = 4/67 (5%)
Query: 91 CISQPCLHNGSCQDSIWGYTCTCSPGYEGSNCELAKNECHPERTDGCQHF-CLPGQESYT 149
C S PC + C D GY C C+ G+EG+ C+ ++C P D C H C+ G S++
Sbjct: 511 CASTPCRNGAKCVDQPDGYECRCAEGFEGTLCDRNVDDCSP---DPCHHGRCVDGIASFS 567
Query: 150 CSCAQGY 156
C+CA GY
Sbjct: 568 CACAPGY 574
Score = 58.2 bits (139), Expect = 1e-08
Identities = 27/67 (40%), Positives = 36/67 (53%), Gaps = 6/67 (8%)
Query: 91 CISQPCLHNGSCQDSIWGYTCTCSPGYEGSNCELAKNECHPERTDGCQH--FCLPGQESY 148
C PC H+G C D I ++C C+PGY G+ CE +EC R+ C+H CL + Y
Sbjct: 549 CSPDPC-HHGRCVDGIASFSCACAPGYTGTRCESQVDEC---RSQPCRHGGKCLDLVDKY 604
Query: 149 TCSCAQG 155
C C G
Sbjct: 605 LCRCPSG 611
Score = 57.8 bits (138), Expect = 2e-08
Identities = 32/75 (42%), Positives = 37/75 (49%), Gaps = 9/75 (12%)
Query: 88 GSPCISQP-CLHNGSCQDSIWGYTCTCSPGYEGSNCELAKNE-----CHPERTDGCQHFC 141
G P S P CLHNG+C D + G+ CTC PGY G CE NE CH T C
Sbjct: 1167 GPPLDSGPRCLHNGTCVDLVGGFRCTCPPGYTGLRCEADINECRSGACHAAHTRDCLQD- 1225
Query: 142 LPGQESYTCSCAQGY 156
PG + C C G+
Sbjct: 1226 -PG-GGFRCLCHAGF 1238
Score = 57.4 bits (137), Expect = 2e-08
Identities = 29/85 (34%), Positives = 38/85 (44%), Gaps = 15/85 (17%)
Query: 91 CISQPCLHNGSCQDSIWGYTCTCSPGYEGSNC-----ELAKNECHPERTDGCQHFCLPGQ 145
C PCL+ GSCQD + ++C+C PG+ G C E N C P C
Sbjct: 853 CDPNPCLNGGSCQDGVGSFSCSCLPGFAGPRCARDVDECLSNPCGPGT-------CTDHV 905
Query: 146 ESYTCSCAQGY---RLGEDHKQCVP 167
S+TC+C GY +D C P
Sbjct: 906 ASFTCTCPPGYGGFHCEQDLPDCSP 930
Score = 57.4 bits (137), Expect = 2e-08
Identities = 30/84 (35%), Positives = 41/84 (48%), Gaps = 9/84 (10%)
Query: 91 CISQPCLHNGSCQDSIWGYTCTCSPGYEGSNCELAKNECHP----ERTDGCQH--FCLPG 144
C SQPC H GSC D + Y C+C PG G CE+ +++C P + C H C+
Sbjct: 1126 CASQPCQHGGSCIDLVARYLCSCPPGTLGVLCEINEDDCGPGPPLDSGPRCLHNGTCVDL 1185
Query: 145 QESYTCSCAQGY---RLGEDHKQC 165
+ C+C GY R D +C
Sbjct: 1186 VGGFRCTCPPGYTGLRCEADINEC 1209
Score = 55.1 bits (131), Expect = 1e-07
Identities = 35/94 (37%), Positives = 44/94 (46%), Gaps = 18/94 (19%)
Query: 91 CISQPCLHNGSCQDSIWGYTCTCSPGYEGSNCELAKNECHPERTDGCQH----FCLPGQE 146
C SQPC G+C G+ CTC PG +G CEL + C P + C+H PGQ
Sbjct: 738 CESQPCRAGGTCSSDGMGFHCTCPPGVQGRQCELL-SPCTP---NPCEHGGRCESAPGQL 793
Query: 147 SYTCSCAQGY---RLGEDHKQCV------PHDQC 171
CSC QG+ R +D +C PH C
Sbjct: 794 P-VCSCPQGWQGPRCQQDVDECAGPAPCGPHGIC 826
Score = 54.7 bits (130), Expect = 1e-07
Identities = 26/70 (37%), Positives = 35/70 (50%), Gaps = 5/70 (7%)
Query: 90 PCISQPCLHNGSCQDSIWG-YTCTCSPGYEGSNCELAKNECHPERTDGCQH--FCLPGQE 146
PC+S PC H C G + C+C PGY+G +C +EC + C+H CL
Sbjct: 122 PCLSSPCAHGARCSVGPDGRFLCSCPPGYQGRSCRSDVDECRV--GEPCRHGGTCLNTPG 179
Query: 147 SYTCSCAQGY 156
S+ C C GY
Sbjct: 180 SFRCQCPAGY 189
Score = 54.3 bits (129), Expect = 2e-07
Identities = 29/82 (35%), Positives = 39/82 (47%), Gaps = 9/82 (10%)
Query: 90 PCISQPCLHNGSC-QDSIWGYTCTCSPGYEGSNCELAKNECHPERTDGCQH--FCLPGQE 146
PC PC + G+C Q Y C C PG+EG NCE+ ++C R C + C+ G
Sbjct: 200 PCAPSPCRNGGTCRQSGDLTYDCACLPGFEGQNCEVNVDDCPGHR---CLNGGTCVDGVN 256
Query: 147 SYTCSCA---QGYRLGEDHKQC 165
+Y C C G ED +C
Sbjct: 257 TYNCQCPPEWTGQFCTEDVDEC 278
Score = 52.0 bits (123), Expect = 9e-07
Identities = 25/67 (37%), Positives = 32/67 (47%), Gaps = 4/67 (5%)
Query: 91 CISQPCLHNGSCQDSIWGYTCTCSPGYEGSNCELAKNECHPERTDGCQH-FCLPGQESYT 149
C SQPC H G C D + Y C C G G NCE+ ++C ++ C C G Y
Sbjct: 586 CRSQPCRHGGKCLDLVDKYLCRCPSGTTGVNCEVNIDDC---ASNPCTFGVCRDGINRYD 642
Query: 150 CSCAQGY 156
C C G+
Sbjct: 643 CVCQPGF 649
Score = 50.1 bits (118), Expect = 4e-06
Identities = 28/88 (31%), Positives = 43/88 (48%), Gaps = 9/88 (10%)
Query: 95 PCLHNGSCQDSIWGYTCTCSPGYEGSNCELAKNECHPERTDGCQH--FCLPGQESYTCSC 152
PC +G C + ++CTC GY G +C+ N+C P + C + C G S++CSC
Sbjct: 819 PCGPHGICTNLAGSFSCTCHGGYTGPSCDQDINDCDP---NPCLNGGSCQDGVGSFSCSC 875
Query: 153 AQGY---RLGEDHKQCVPHDQCACGVLT 177
G+ R D +C+ + C G T
Sbjct: 876 LPGFAGPRCARDVDECL-SNPCGPGTCT 902
Score = 49.7 bits (117), Expect = 5e-06
Identities = 29/91 (31%), Positives = 39/91 (42%), Gaps = 12/91 (13%)
Query: 91 CISQPCLHNGSCQDSIWGYTCTCSPGYEGSNCELAKNECHPERTDGCQHFCLPGQESYTC 150
C S PC G C+D I Y C C PG+ G C + NEC G C+ G+ + C
Sbjct: 624 CASNPCTF-GVCRDGINRYDCVCQPGFTGPLCNVEINEC-ASSPCGEGGSCVDGENGFRC 681
Query: 151 SCAQGYRLGEDHKQCVP------HDQCACGV 175
C G C+P H+ C+ G+
Sbjct: 682 LCPP----GSLPPLCLPPSHPCAHEPCSHGI 708
Score = 49.3 bits (116), Expect = 6e-06
Identities = 25/84 (29%), Positives = 37/84 (44%), Gaps = 4/84 (4%)
Query: 89 SPCISQPCLHNGSCQDSIWGY-TCTCSPGYEGSNCELAKNECHPERTDGCQHFCLPGQES 147
SPC PC H G C+ + C+C G++G C+ +EC G C S
Sbjct: 773 SPCTPNPCEHGGRCESAPGQLPVCSCPQGWQGPRCQQDVDECAGPAPCGPHGICTNLAGS 832
Query: 148 YTCSCAQGY---RLGEDHKQCVPH 168
++C+C GY +D C P+
Sbjct: 833 FSCTCHGGYTGPSCDQDINDCDPN 856
Score = 48.9 bits (115), Expect = 8e-06
Identities = 21/68 (30%), Positives = 36/68 (52%), Gaps = 5/68 (7%)
Query: 91 CISQPCLHNGSCQDSIWGYTCTCSPGYEGSNCELAKNECHPERTDGCQH--FCLPGQESY 148
C+S PC + +C D I +TC C G+ G+ CE+ +EC ++ C + C +
Sbjct: 435 CLSGPCRNQATCLDRIGQFTCICMAGFTGTYCEVDIDEC---QSSPCVNGGVCKDRVNGF 491
Query: 149 TCSCAQGY 156
+C+C G+
Sbjct: 492 SCTCPSGF 499
Score = 47.8 bits (112), Expect = 2e-05
Identities = 19/68 (27%), Positives = 33/68 (48%), Gaps = 5/68 (7%)
Query: 91 CISQPCLHNGSCQDSIWGYTCTCSPGYEGSNCELAKNECHPERTDGCQH--FCLPGQESY 148
C C + G+C D + ++C C PGY G++C+ +E P + C H C +
Sbjct: 928 CSPSSCFNGGTCVDGVNSFSCLCRPGYTGAHCQ---HEADPCLSRPCLHGGVCSAAHPGF 984
Query: 149 TCSCAQGY 156
C+C + +
Sbjct: 985 RCTCLESF 992
Score = 47.4 bits (111), Expect = 2e-05
Identities = 25/70 (35%), Positives = 33/70 (47%), Gaps = 8/70 (11%)
Query: 90 PCISQPCLHNGSCQDSIWGYTCTCSPGYEGSNC--ELAKNEC--HPERTDGCQHFCLPGQ 145
PC +PC H G C D+ G+ C C PG+ G C LA++ C P R G C
Sbjct: 698 PCAHEPCSH-GICYDAPGGFRCVCEPGWSGPRCSQSLARDACESQPCRAGGT---CSSDG 753
Query: 146 ESYTCSCAQG 155
+ C+C G
Sbjct: 754 MGFHCTCPPG 763
Score = 47.4 bits (111), Expect = 2e-05
Identities = 22/67 (32%), Positives = 32/67 (47%), Gaps = 3/67 (4%)
Query: 90 PCISQPCLHNGSCQDSIWGYTCTCSPGYEGSNCELAKNECHPERTDGCQHFCLPGQESYT 149
PC+S+PCLH G C + G+ CTC + G C+ + C + CQ+ Q
Sbjct: 965 PCLSRPCLHGGVCSAAHPGFRCTCLESFTGPQCQTLVDWCSRQ---PCQNGGRCVQTGAY 1021
Query: 150 CSCAQGY 156
C C G+
Sbjct: 1022 CLCPPGW 1028
Score = 45.8 bits (107), Expect = 7e-05
Identities = 24/66 (36%), Positives = 30/66 (45%), Gaps = 5/66 (7%)
Query: 93 SQPCLHNGSCQDSIWGYTCTCSPGYEGSNCELAKNEC--HPERTDGCQHFCLPGQESYTC 150
+ PC H G C ++ + C C GY G CE NEC P R Q CL +TC
Sbjct: 399 ANPCEHLGRCVNTQGSFLCQCGRGYTGPRCETDVNECLSGPCRN---QATCLDRIGQFTC 455
Query: 151 SCAQGY 156
C G+
Sbjct: 456 ICMAGF 461
Score = 45.4 bits (106), Expect = 9e-05
Identities = 28/92 (30%), Positives = 37/92 (40%), Gaps = 16/92 (17%)
Query: 91 CISQPCLHNGSCQDSIWGYTCTCSPGYEG-------SNCELAKNECHPERTDGCQHFCLP 143
C CL+ G+C D + Y C C P + G C+L N CH T C
Sbjct: 240 CPGHRCLNGGTCVDGVNTYNCQCPPEWTGQFCTEDVDECQLQPNACHNGGT------CFN 293
Query: 144 GQESYTCSCAQGYRLGEDHKQCVPHDQCACGV 175
++C C G+ GE Q + D CA V
Sbjct: 294 TLGGHSCVCVNGW-TGESCSQNI--DDCATAV 322
Score = 45.1 bits (105), Expect = 1e-04
Identities = 26/101 (25%), Positives = 41/101 (40%), Gaps = 10/101 (9%)
Query: 92 ISQPCLHNGSCQDSIWGYTCTCSPGYEGSNCELAKNECHPERTDGCQHFCLPGQESYTCS 151
+ +PC H G+C ++ + C C GY G CE C P G +Y C+
Sbjct: 164 VGEPCRHGGTCLNTPGSFRCQCPAGYTGPLCENPAVPCAPSPCRNGGTCRQSGDLTYDCA 223
Query: 152 CAQGYRLGEDHK---------QCVPHDQCACGVLTSEKRAP 183
C G+ G++ + +C+ C GV T + P
Sbjct: 224 CLPGFE-GQNCEVNVDDCPGHRCLNGGTCVDGVNTYNCQCP 263
Score = 44.7 bits (104), Expect = 2e-04
Identities = 29/87 (33%), Positives = 40/87 (45%), Gaps = 10/87 (11%)
Query: 90 PCIS-QPCLHNGSC-QDSIWGYTCTCSPGYEGSNCELAKNECHPERTDG---CQHFCLPG 144
PC+ PC + G C Q C C PG+ G C+L ++ CH G CQ + G
Sbjct: 42 PCLDGSPCANGGRCTQLPSREAACLCPPGWVGERCQL-EDPCHSGPCAGRGVCQSSVVAG 100
Query: 145 QESYTCSCAQGYRLGEDHKQCVPHDQC 171
++C C +G+R G D C D C
Sbjct: 101 TARFSCRCPRGFR-GPD---CSLPDPC 123
Score = 43.9 bits (102), Expect = 3e-04
Identities = 30/92 (32%), Positives = 41/92 (44%), Gaps = 14/92 (15%)
Query: 90 PCISQPCLHNGSCQDSIWG----YTCTCSPGYEGSNCELAKNECHPERTDGCQH--FCLP 143
PC S PC G CQ S+ ++C C G+ G +C L P + C H C
Sbjct: 81 PCHSGPCAGRGVCQSSVVAGTARFSCRCPRGFRGPDCSLP----DPCLSSPCAHGARCSV 136
Query: 144 GQES-YTCSCAQGYRLGEDHKQCVPHDQCACG 174
G + + CSC GY+ G + V D+C G
Sbjct: 137 GPDGRFLCSCPPGYQ-GRSCRSDV--DECRVG 165
Score = 43.1 bits (100), Expect = 4e-04
Identities = 28/83 (33%), Positives = 35/83 (42%), Gaps = 8/83 (9%)
Query: 92 ISQPCLHNGSCQDSIWGYTCTCSPGYEGSNCELAKNECHPERTDGCQH--FCLPGQESYT 149
+ Q C G C D + C C G GS+CE E P CQH C Y
Sbjct: 1051 LEQLCQAGGQCVDEDSSHYCVCPEGRTGSHCE---QEVDPCLAQPCQHGGTCRGYMGGYM 1107
Query: 150 CSCAQGYRLGEDHKQCVPHDQCA 172
C C GY G++ + V D+CA
Sbjct: 1108 CECLPGYN-GDNCEDDV--DECA 1127
Score = 42.4 bits (98), Expect = 8e-04
Identities = 26/92 (28%), Positives = 34/92 (36%), Gaps = 15/92 (16%)
Query: 89 SPCISQPCLHNGSCQDSI-----WGYTCTCSPGYEGSNCELAKNECH----------PER 133
SPC SQPC H G C+ S +TC C+ + G CE C +
Sbjct: 1248 SPCESQPCQHGGQCRPSPGPGGGLTFTCHCAQPFWGPRCERVARSCRELQCPVGVPCQQT 1307
Query: 134 TDGCQHFCLPGQESYTCSCAQGYRLGEDHKQC 165
G + C PG +C G G + C
Sbjct: 1308 PRGPRCACPPGLSGPSCRSFPGSPPGASNASC 1339
Score = 38.9 bits (89), Expect = 0.008
Identities = 29/119 (24%), Positives = 39/119 (32%), Gaps = 43/119 (36%)
Query: 91 CISQPCLHNGSCQDSIWGYTCTCSPGYEGSNCEL----AKNECH---------------- 130
C + C H +C D + + C C G G C L N CH
Sbjct: 318 CATAVCFHGATCHDRVASFYCACPMGKTGLLCHLDDACVSNPCHEDAICDTNPVNGRAIC 377
Query: 131 ---PERTDG---------------CQHF--CLPGQESYTCSCAQGY---RLGEDHKQCV 166
P T G C+H C+ Q S+ C C +GY R D +C+
Sbjct: 378 TCPPGFTGGACDQDVDECSIGANPCEHLGRCVNTQGSFLCQCGRGYTGPRCETDVNECL 436
Score = 38.9 bits (89), Expect = 0.008
Identities = 25/76 (32%), Positives = 33/76 (43%), Gaps = 13/76 (17%)
Query: 91 CISQPC--LHNGSC-QDSIWGYTCTCSPGYEGSNCELAKNECHPERTDGCQH--FCLP-- 143
C S C H C QD G+ C C G+ G C+ + C + CQH C P
Sbjct: 1209 CRSGACHAAHTRDCLQDPGGGFRCLCHAGFSGPRCQTVLSPC---ESQPCQHGGQCRPSP 1265
Query: 144 ---GQESYTCSCAQGY 156
G ++TC CAQ +
Sbjct: 1266 GPGGGLTFTCHCAQPF 1281
Score = 37.4 bits (85), Expect = 0.024
Identities = 26/90 (28%), Positives = 36/90 (40%), Gaps = 14/90 (15%)
Query: 91 CISQPCLHNGSCQDSIWGYTCTCSPGYEGSNCELAKNECHP---------ERTDGCQHFC 141
C QPC + G C + G C C PG+ G C++ C E+ C
Sbjct: 1004 CSRQPCQNGGRCVQT--GAYCLCPPGWSGRLCDIRSLPCREAAAQIGVRLEQLCQAGGQC 1061
Query: 142 LPGQESYTCSCAQGYRLGEDHKQCVPHDQC 171
+ S+ C C +G R G +Q V D C
Sbjct: 1062 VDEDSSHYCVCPEG-RTGSHCEQEV--DPC 1088
Score = 37.4 bits (85), Expect = 0.024
Identities = 17/49 (34%), Positives = 24/49 (48%), Gaps = 8/49 (16%)
Query: 83 RRYKGGSP------CISQPCLHNGSCQDSIWG--YTCTCSPGYEGSNCE 123
R + G P C + PCLH GSC+ + + C C+ G+ G CE
Sbjct: 1325 RSFPGSPPGASNASCAAAPCLHGGSCRPAPLAPFFRCACAQGWTGPRCE 1373
>gi|110347457 EGF-like-domain, multiple 3 [Homo sapiens]
Length = 1541
Score = 67.0 bits (162), Expect = 3e-11
Identities = 30/84 (35%), Positives = 40/84 (47%), Gaps = 2/84 (2%)
Query: 91 CISQPCLHNGSCQDSIWGYTCTCSPGYEGSNCELAKNECHPERTDGCQHFCLPGQESYTC 150
C + C H G C C C PG++G C+ +EC GCQH C+ SY C
Sbjct: 128 CSASLCFHGGRCVPGS-AQPCHCPPGFQGPRCQYDVDECRTHN-GGCQHRCVNTPGSYLC 185
Query: 151 SCAQGYRLGEDHKQCVPHDQCACG 174
C G+RL D + C+ + CA G
Sbjct: 186 ECKPGFRLHTDSRTCLAINSCALG 209
Score = 60.5 bits (145), Expect = 3e-09
Identities = 34/86 (39%), Positives = 42/86 (48%), Gaps = 12/86 (13%)
Query: 89 SPCISQPCLHNGSCQDSIWGYTCTCSPGY----EGSNCELAKNECHPERTDGCQHFCLPG 144
SPC Q C +N GY C C GY +G CE +EC R GC+H C
Sbjct: 379 SPCCQQVCTNNPG------GYECGCYAGYRLSADGCGCEDV-DECASSR-GGCEHHCTNL 430
Query: 145 QESYTCSCAQGYRLGEDHKQCVPHDQ 170
S+ CSC GYRL ED + C P ++
Sbjct: 431 AGSFQCSCEAGYRLHEDRRGCSPLEE 456
Score = 50.4 bits (119), Expect = 3e-06
Identities = 30/93 (32%), Positives = 43/93 (46%), Gaps = 11/93 (11%)
Query: 92 ISQPCLHNGSCQD-----SIWGYTCTCSPGYE----GSNCELAKNECHPERTDGCQHFCL 142
I+ L NG CQ +I + C C PG++ G +C + ++ C R C H C
Sbjct: 203 INSCALGNGGCQHHCVQLTITRHRCQCRPGFQLQEDGRHC-VRRSPC-ANRNGSCMHRCQ 260
Query: 143 PGQESYTCSCAQGYRLGEDHKQCVPHDQCACGV 175
+ C C GY+L D K C D+CA G+
Sbjct: 261 VVRGLARCECHVGYQLAADGKACEDVDECAAGL 293
Score = 47.0 bits (110), Expect = 3e-05
Identities = 26/85 (30%), Positives = 34/85 (40%), Gaps = 11/85 (12%)
Query: 96 CLHNGSCQDSIWGYTCTCSPGYE----GSNCELAK----NECHPERTDGCQHFCLPGQES 147
C H C ++ + C C GYE G C + N C GC H C
Sbjct: 296 CAHG--CLNTQGSFKCVCHAGYELGADGRQCYRIEMEIVNSCEANN-GGCSHGCSHTSAG 352
Query: 148 YTCSCAQGYRLGEDHKQCVPHDQCA 172
C+C +GY L D + C+ D CA
Sbjct: 353 PLCTCPRGYELDTDQRTCIDVDDCA 377
Score = 46.2 bits (108), Expect = 5e-05
Identities = 31/83 (37%), Positives = 38/83 (45%), Gaps = 10/83 (12%)
Query: 89 SPCISQ--PCLHNGSCQDSIWGYTCTCSPGYE----GSNCELAKNECHPERTDGCQHFCL 142
SPC ++ C+H CQ C C GY+ G CE +EC C H CL
Sbjct: 246 SPCANRNGSCMHR--CQVVRGLARCECHVGYQLAADGKACEDV-DECAAGLAQ-CAHGCL 301
Query: 143 PGQESYTCSCAQGYRLGEDHKQC 165
Q S+ C C GY LG D +QC
Sbjct: 302 NTQGSFKCVCHAGYELGADGRQC 324
Score = 43.1 bits (100), Expect = 4e-04
Identities = 32/102 (31%), Positives = 41/102 (40%), Gaps = 19/102 (18%)
Query: 82 WRRYKGGSPCI----SQPCLHNGSCQDSIWGY----TCTCSPGYEGSNCELAKNECHP-E 132
W K SPC+ + C SC + C C PG+ GS CE A C P
Sbjct: 1110 WTGDKCQSPCLRGWFGEACAQRCSCPPGAACHHVTGACRCPPGFTGSGCEQA---CPPGS 1166
Query: 133 RTDGCQHFC-LPGQE------SYTCSCAQGYRLGEDHKQCVP 167
+ C C PG+ + TCSCA GY ++C P
Sbjct: 1167 FGEDCAQMCQCPGENPACHPATGTCSCAAGYHGPSCQQRCPP 1208
Score = 42.7 bits (99), Expect = 6e-04
Identities = 26/80 (32%), Positives = 32/80 (40%), Gaps = 7/80 (8%)
Query: 96 CLHNGSCQDSIWGYTCTCSPGYEGSNCE---LAKNECHPERTDGCQHFCLPGQESYTCSC 152
C H C + G CTC GYE + + ++C CQ C Y C C
Sbjct: 342 CSHG--CSHTSAGPLCTCPRGYELDTDQRTCIDVDDCADSPC--CQQVCTNNPGGYECGC 397
Query: 153 AQGYRLGEDHKQCVPHDQCA 172
GYRL D C D+CA
Sbjct: 398 YAGYRLSADGCGCEDVDECA 417
Score = 37.4 bits (85), Expect = 0.024
Identities = 27/75 (36%), Positives = 33/75 (44%), Gaps = 9/75 (12%)
Query: 90 PCISQPC---LHNGSCQDSIWGYTCTCSPGYEGSNCELAKNECH----PERTDGCQHFCL 142
P S PC +GSC D+I G C C GY G CE + H E+ CQH
Sbjct: 867 PDCSHPCNCSAGHGSC-DAISGL-CLCEAGYVGPRCEQQCPQGHFGPGCEQRCQCQHGAA 924
Query: 143 PGQESYTCSCAQGYR 157
S C+C G+R
Sbjct: 925 CDHVSGACTCPAGWR 939
Score = 37.4 bits (85), Expect = 0.024
Identities = 27/89 (30%), Positives = 38/89 (42%), Gaps = 11/89 (12%)
Query: 88 GSPCISQPCLHNGSCQDSIWGYTCTCSPGYEGSNCELAKNECHPE-RTDGCQHFCL---- 142
G C NG+ D + G C C+PG+ G +C A C D C+H CL
Sbjct: 996 GHNCSQACACFNGASCDPVHGQ-CHCAPGWMGPSCLQA---CPAGLYGDNCRHSCLCQNG 1051
Query: 143 --PGQESYTCSCAQGYRLGEDHKQCVPHD 169
S C+C +G+ K+C+P D
Sbjct: 1052 GTCDPVSGHCACPEGWAGLACEKECLPRD 1080
Score = 36.6 bits (83), Expect = 0.041
Identities = 28/100 (28%), Positives = 37/100 (37%), Gaps = 18/100 (18%)
Query: 88 GSPCISQPCLHNGSCQDSIWGYTCTCSPGYEGSNCELAKNECHP-------ERTDGCQHF 140
G+ C + HN S + G TC C PG+ G CE + C P + CQH
Sbjct: 1341 GAACHLECSCHNNSTCEPATG-TCRCGPGFYGQACE---HPCPPGFHGAGCQGLCWCQHG 1396
Query: 141 CLPGQESYTCSCAQGYRLGEDHKQCVP-------HDQCAC 173
S C C G+ + C P H +C C
Sbjct: 1397 APCDPISGRCLCPAGFHGHFCERGCEPGSFGEGCHQRCDC 1436
Score = 35.8 bits (81), Expect = 0.070
Identities = 27/88 (30%), Positives = 35/88 (39%), Gaps = 18/88 (20%)
Query: 100 GSCQDSIWGYTCTCSPGYEGSNCELAKNECHPERTD-GCQHFC------LPGQESYTCSC 152
G+ D + G TC C PG G CE C R GC+H C L + +CSC
Sbjct: 1267 GAACDPVTG-TCLCPPGRAGVRCE---RGCPQNRFGVGCEHTCSCRNGGLCHASNGSCSC 1322
Query: 153 AQGYRLGEDHKQCVP-------HDQCAC 173
G+ C P H +C+C
Sbjct: 1323 GLGWTGRHCELACPPGRYGAACHLECSC 1350
Score = 34.3 bits (77), Expect = 0.20
Identities = 25/80 (31%), Positives = 32/80 (40%), Gaps = 14/80 (17%)
Query: 88 GSPC-ISQPCLHNGSCQDSIWGYTCTCSPGYEGSNCELAKNECHPERTDGCQHFCLPGQE 146
G C S C + G+C DS+ G C C PG G+NCE DGC
Sbjct: 561 GKNCSFSCSCQNGGTC-DSVTG-ACRCPPGVSGTNCE-----------DGCPKGYYGKHC 607
Query: 147 SYTCSCAQGYRLGEDHKQCV 166
C+CA R + C+
Sbjct: 608 RKKCNCANRGRCHRLYGACL 627
Score = 33.5 bits (75), Expect = 0.35
Identities = 28/86 (32%), Positives = 38/86 (44%), Gaps = 13/86 (15%)
Query: 96 CLHNGSCQDSIWGYTCTCSPGYEGSNCELAKNECHPER-TDGCQHFCLPGQESY------ 148
CL+ GSC D+ G C C G+ G++C L C R C H C GQ +
Sbjct: 1221 CLNGGSC-DAATG-ACRCPTGFLGTDCNLT---CPQGRFGPNCTHVCGCGQGAACDPVTG 1275
Query: 149 TCSCAQGYRLGEDHKQCVPHDQCACG 174
TC C G R G ++ P ++ G
Sbjct: 1276 TCLCPPG-RAGVRCERGCPQNRFGVG 1300
Score = 33.1 bits (74), Expect = 0.46
Identities = 20/60 (33%), Positives = 26/60 (43%), Gaps = 5/60 (8%)
Query: 96 CLHNGSCQDSIWGYTCTCSPGYEGSNCELAKNECHPERTDGCQHFCLPGQESYTCSCAQG 155
C + G C S +C+C G+ G +CELA C P R H + TC A G
Sbjct: 1307 CRNGGLCHAS--NGSCSCGLGWTGRHCELA---CPPGRYGAACHLECSCHNNSTCEPATG 1361
Score = 32.7 bits (73), Expect = 0.60
Identities = 23/77 (29%), Positives = 36/77 (46%), Gaps = 11/77 (14%)
Query: 96 CLHNGSCQDSIWGYTCTCSPGYEGSNCELAKNECH--PERTDGCQHFCLPGQESY----- 148
C ++G C + G+ C+C+PG+ G +C+ A + H P+ + C C G S
Sbjct: 832 CANDGHCHPAT-GH-CSCAPGWTGFSCQRACDTGHWGPDCSHPCN--CSAGHGSCDAISG 887
Query: 149 TCSCAQGYRLGEDHKQC 165
C C GY +QC
Sbjct: 888 LCLCEAGYVGPRCEQQC 904
Score = 29.6 bits (65), Expect = 5.0
Identities = 22/70 (31%), Positives = 27/70 (38%), Gaps = 17/70 (24%)
Query: 87 GGSPCISQPCLHNGSCQDSIWGYTCTCSPGYEGSNCELAKNECHPERTD-GCQHFCLPGQ 145
GG+PC H + Q C C PG G +CE +C R GCQ C Q
Sbjct: 747 GGAPC------HGVTGQ-------CRCPPGRTGEDCEA---DCPEGRWGLGCQEICPACQ 790
Query: 146 ESYTCSCAQG 155
+ C G
Sbjct: 791 HAARCDPETG 800
Score = 29.6 bits (65), Expect = 5.0
Identities = 24/93 (25%), Positives = 31/93 (33%), Gaps = 25/93 (26%)
Query: 84 RYKGGSPCISQPCLHNGSCQDSIWGYTCTCSPGYEGSNCE------------------LA 125
R+ G I C H C C C PG+ GS C+
Sbjct: 777 RWGLGCQEICPACQHAARCDPETGA--CLCLPGFVGSRCQDVCPAGWYGPSCQTRCSCAN 834
Query: 126 KNECHPERTDGCQHFCLPGQESYTC--SCAQGY 156
CHP T C C PG ++C +C G+
Sbjct: 835 DGHCHP-ATGHCS--CAPGWTGFSCQRACDTGH 864
Score = 29.3 bits (64), Expect = 6.6
Identities = 24/79 (30%), Positives = 31/79 (39%), Gaps = 14/79 (17%)
Query: 96 CLHNGSCQDSIWGYTCTCSPGYEGSNCELAKNECHP-ERTDGCQHFC---LPGQESY--- 148
C + G C ++G C C PG G C L C P GC C P +S
Sbjct: 613 CANRGRCH-RLYG-ACLCDPGLYGRFCHLT---CPPWAFGPGCSEECQCVQPHTQSCDKR 667
Query: 149 --TCSCAQGYRLGEDHKQC 165
+CSC G+R +C
Sbjct: 668 DGSCSCKAGFRGERCQAEC 686
>gi|4503635 coagulation factor II preproprotein [Homo sapiens]
Length = 622
Score = 66.2 bits (160), Expect = 5e-11
Identities = 37/85 (43%), Positives = 50/85 (58%), Gaps = 6/85 (7%)
Query: 1 MAGCVPLLQGLVLVLALHRVEPSVFLPASKANDVLVRWKRAGSYLLEELFEGNLEKECYE 60
+ GC+ L LV + H VFL +A +L R +RA ++L EE+ +GNLE+EC E
Sbjct: 9 LPGCLALAALCSLVHSQH-----VFLAPQQARSLLQRVRRANTFL-EEVRKGNLERECVE 62
Query: 61 EICVYEEAREVFENEVVTDEFWRRY 85
E C YEEA E E+ TD FW +Y
Sbjct: 63 ETCSYEEAFEALESSTATDVFWAKY 87
Score = 57.4 bits (137), Expect = 2e-08
Identities = 47/172 (27%), Positives = 83/172 (48%), Gaps = 22/172 (12%)
Query: 189 PWQVKLTNSEGKDF-CGGVIIRENFVLTTAKCSLL---HRNITVKTYF------NRTSQD 238
PWQV L ++ CG +I + +VLT A C L +N T +RT +
Sbjct: 376 PWQVMLFRKSPQELLCGASLISDRWVLTAAHCLLYPPWDKNFTENDLLVRIGKHSRTRYE 435
Query: 239 PLMIKIT---HVHVHMRYD-ADAGENDLSLLELEWPIQCPGAGLPVCTPEKDFAEHLLIP 294
+ KI+ +++H RY+ + + D++L++L+ P+ PVC P+++ A LL
Sbjct: 436 RNIEKISMLEKIYIHPRYNWRENLDRDIALMKLKKPVAFSDYIHPVCLPDRETAASLLQA 495
Query: 295 RTRGLLSGWARNGTDLGNSLTTRPVTLVEGE-ECGQVLNVTVTTRTYCERSS 345
+G ++GW GN T + +G+ QV+N+ + R C+ S+
Sbjct: 496 GYKGRVTGW-------GNLKETWTANVGKGQPSVLQVVNLPIVERPVCKDST 540
>gi|41327708 crumbs homolog 1 precursor [Homo sapiens]
Length = 1406
Score = 66.2 bits (160), Expect = 5e-11
Identities = 27/64 (42%), Positives = 40/64 (62%), Gaps = 5/64 (7%)
Query: 91 CISQPCLHNGSCQDSIWGYTCTCSPGYEGSNCELAKNECHPERTDGCQH--FCLPGQESY 148
C SQPCL+ +CQD++ Y C C+PG+ G +CEL +EC + C H C+ G+ Y
Sbjct: 228 CWSQPCLNGATCQDALGAYFCDCAPGFLGDHCELNTDEC---ASQPCLHGGLCVDGENRY 284
Query: 149 TCSC 152
+C+C
Sbjct: 285 SCNC 288
Score = 62.8 bits (151), Expect = 5e-10
Identities = 29/68 (42%), Positives = 38/68 (55%), Gaps = 5/68 (7%)
Query: 91 CISQPCLHNGSCQDSIWGYTCTCSPGYEGSNCELAKNECHPERTDGCQH--FCLPGQESY 148
C S PC + CQD I GY+C C PGY+G +C+L +EC +D C++ CL Y
Sbjct: 152 CASSPCQNGAVCQDGIDGYSCFCVPGYQGRHCDLEVDEC---ASDPCKNEATCLNEIGRY 208
Query: 149 TCSCAQGY 156
TC C Y
Sbjct: 209 TCICPHNY 216
Score = 60.8 bits (146), Expect = 2e-09
Identities = 34/88 (38%), Positives = 44/88 (50%), Gaps = 8/88 (9%)
Query: 91 CISQPCLHNGSCQDSIWGYTCTCSPGYEGSNCELAKNECHPERTDGCQH-FCLPGQESYT 149
C S PCLH G+C+D Y C+C G+ G +CEL +EC ++ C H C +Y
Sbjct: 1143 CNSNPCLHGGNCEDIYSSYHCSCPLGWSGKHCELNIDECF---SNPCIHGNCSDRVAAYH 1199
Query: 150 CSCAQGY---RLGEDHKQCVPHDQCACG 174
C+C GY D C H QCA G
Sbjct: 1200 CTCEPGYTGVNCEVDIDNCQSH-QCANG 1226
Score = 57.0 bits (136), Expect = 3e-08
Identities = 21/40 (52%), Positives = 29/40 (72%)
Query: 91 CISQPCLHNGSCQDSIWGYTCTCSPGYEGSNCELAKNECH 130
C S+PC +N +C+DS+ YTC C PGY G+ CE+ NEC+
Sbjct: 305 CWSKPCHNNATCEDSVDNYTCHCWPGYTGAQCEIDLNECN 344
Score = 54.3 bits (129), Expect = 2e-07
Identities = 36/111 (32%), Positives = 49/111 (44%), Gaps = 18/111 (16%)
Query: 91 CISQPCLHNGSCQDSIWGYTCTCS-PGYEGSNCELA-----KNECHPERTDGCQHFCLPG 144
C SQPCLH G C D Y+C C+ G+ G++CE CH T C
Sbjct: 266 CASQPCLHGGLCVDGENRYSCNCTGSGFTGTHCETLMPLCWSKPCHNNAT------CEDS 319
Query: 145 QESYTCSCAQGYRLGE---DHKQCVPH---DQCACGVLTSEKRAPDLQDLP 189
++YTC C GY + D +C + C L+SEK+ + LP
Sbjct: 320 VDNYTCHCWPGYTGAQCEIDLNECNSNPCQSNGECVELSSEKQYGRITGLP 370
Score = 53.9 bits (128), Expect = 2e-07
Identities = 32/83 (38%), Positives = 43/83 (51%), Gaps = 6/83 (7%)
Query: 91 CISQPCLHNGSCQDSIWGYTCTCSPGYEGSNCELAKNECHPER-TDGCQHFCLPGQESYT 149
C S PC + +C + I YTC C Y G NCEL +EC + +G C +Y
Sbjct: 190 CASDPCKNEATCLNEIGRYTCICPHNYSGVNCELEIDECWSQPCLNGAT--CQDALGAYF 247
Query: 150 CSCAQGYRLGEDHKQCVPHDQCA 172
C CA G+ LG DH + + D+CA
Sbjct: 248 CDCAPGF-LG-DHCE-LNTDECA 267
Score = 47.8 bits (112), Expect = 2e-05
Identities = 26/70 (37%), Positives = 34/70 (48%), Gaps = 7/70 (10%)
Query: 91 CISQPCLHNGSC-QDSIWGYTCTCSPGYEGSNCELAKNECHPERTDGCQH--FCLPGQES 147
C C H G C QD I+ C C GY G CE+ +EC + CQ+ C G +
Sbjct: 114 CGKNSCQHGGICHQDPIYP-VCICPAGYAGRFCEIDHDEC---ASSPCQNGAVCQDGIDG 169
Query: 148 YTCSCAQGYR 157
Y+C C GY+
Sbjct: 170 YSCFCVPGYQ 179
Score = 47.8 bits (112), Expect = 2e-05
Identities = 38/133 (28%), Positives = 50/133 (37%), Gaps = 47/133 (35%)
Query: 82 WRRYKGG------SPCISQPCLHNGSCQD--------------------SIWGYTCTCSP 115
W Y G + C S PC NG C + GY C C P
Sbjct: 328 WPGYTGAQCEIDLNECNSNPCQSNGECVELSSEKQYGRITGLPSSFSYHEASGYVCICQP 387
Query: 116 GYEGSNCELAKNEC--HPERTDG-CQHFCLPGQESYTCSC--------------AQGYRL 158
G+ G +CE NEC +P + G C++ LPG +YTC C L
Sbjct: 388 GFTGIHCEEDVNECSSNPCQNGGTCEN--LPG--NYTCHCPFDNLSRTFYGGRDCSDILL 443
Query: 159 GEDHKQCVPHDQC 171
G H+QC+ + C
Sbjct: 444 GCTHQQCLNNGTC 456
Score = 47.4 bits (111), Expect = 2e-05
Identities = 29/89 (32%), Positives = 40/89 (44%), Gaps = 14/89 (15%)
Query: 90 PCISQPCLHNGSCQDSIW--GYTCTCSPGYEGSNCELAKNECHPERTDGCQHFCLPGQES 147
PC S PC + +C ++ + C C PGY G+ CE C + CQH + Q+
Sbjct: 73 PCFSNPCQGSATCVNTPGERSFLCKCPPGYSGTICETTIGSC---GKNSCQHGGICHQDP 129
Query: 148 Y--TCSCAQGY--RLGEDHKQCVPHDQCA 172
C C GY R E + HD+CA
Sbjct: 130 IYPVCICPAGYAGRFCE-----IDHDECA 153
Score = 43.9 bits (102), Expect = 3e-04
Identities = 19/39 (48%), Positives = 24/39 (61%), Gaps = 4/39 (10%)
Query: 91 CISQPCLHNGSC----QDSIWGYTCTCSPGYEGSNCELA 125
C Q CL+NG+C QD G++C C GY GS CE+A
Sbjct: 445 CTHQQCLNNGTCIPHFQDGQHGFSCLCPSGYTGSLCEIA 483
Score = 42.0 bits (97), Expect = 0.001
Identities = 22/75 (29%), Positives = 34/75 (45%), Gaps = 5/75 (6%)
Query: 86 KGGSPCISQPCLHNGSCQDSIWGYTCTCSPGYEG--SNCELAKNECHPERTDGCQHFCL- 142
K + C+S C +N +C+D C+CS +C+ K+ C G C+
Sbjct: 29 KNNTRCLSNSCQNNSTCKDFSKDNDCSCSDTANNLDKDCDNMKDPCFSNPCQG-SATCVN 87
Query: 143 -PGQESYTCSCAQGY 156
PG+ S+ C C GY
Sbjct: 88 TPGERSFLCKCPPGY 102
Score = 38.5 bits (88), Expect = 0.011
Identities = 24/77 (31%), Positives = 33/77 (42%), Gaps = 13/77 (16%)
Query: 91 CISQPCLHNGSCQDSIWGYTCTCSPGYEGSNCELAKNECHPERTDGCQH-------FCLP 143
C S PC + G+C++ YTC C P S +C + GC H C+P
Sbjct: 401 CSSNPCQNGGTCENLPGNYTCHC-PFDNLSRTFYGGRDCS-DILLGCTHQQCLNNGTCIP 458
Query: 144 ----GQESYTCSCAQGY 156
GQ ++C C GY
Sbjct: 459 HFQDGQHGFSCLCPSGY 475
Score = 38.5 bits (88), Expect = 0.011
Identities = 13/34 (38%), Positives = 19/34 (55%)
Query: 91 CISQPCLHNGSCQDSIWGYTCTCSPGYEGSNCEL 124
C S PC++ G CQD + + C C + G CE+
Sbjct: 1301 CASDPCVNGGLCQDLLNKFQCLCDVAFAGERCEV 1334
Score = 36.6 bits (83), Expect = 0.041
Identities = 15/32 (46%), Positives = 16/32 (50%)
Query: 91 CISQPCLHNGSCQDSIWGYTCTCSPGYEGSNC 122
C SQPC G C + Y C C YEG NC
Sbjct: 676 CESQPCQSRGRCINLWLSYQCDCHRPYEGPNC 707
Score = 33.9 bits (76), Expect = 0.27
Identities = 26/98 (26%), Positives = 37/98 (37%), Gaps = 10/98 (10%)
Query: 91 CISQPCLHNGSCQDSIWGYTCTCSPGYEGSNC---ELAKNECHPERTD-GCQH--FCLPG 144
C S C + +C GY+C C + G C L C E+T+ C + C
Sbjct: 1218 CQSHQCANGATCISHTNGYSCLCFGNFTGKFCRQSRLPSTVCGNEKTNLTCYNGGNCTEF 1277
Query: 145 QESYTCSCAQGYR---LGEDHKQCVPHDQCACGVLTSE 179
Q C C G+ +D +C D C G L +
Sbjct: 1278 QTELKCMCRPGFTGEWCEKDIDECA-SDPCVNGGLCQD 1314
Score = 32.7 bits (73), Expect = 0.60
Identities = 17/59 (28%), Positives = 25/59 (42%), Gaps = 5/59 (8%)
Query: 96 CLHNGSCQDSIWGYTCTCSPGYEGSNCELAKNECHPERTDGCQH--FCLPGQESYTCSC 152
C + G+C + C C PG+ G CE +EC +D C + C + C C
Sbjct: 1268 CYNGGNCTEFQTELKCMCRPGFTGEWCEKDIDEC---ASDPCVNGGLCQDLLNKFQCLC 1323
Score = 32.0 bits (71), Expect = 1.0
Identities = 20/84 (23%), Positives = 31/84 (36%), Gaps = 7/84 (8%)
Query: 47 EELFEGNLEKECYEEICVYEEAREVFENEV-------VTDEFWRRYKGGSPCISQPCLHN 99
E G K C +++ + + E F N V + G + C S PC +
Sbjct: 840 ETELNGGFFKGCIQDVRLNNQNLEFFPNPTNNASLNPVLVNVTQGCAGDNSCKSNPCHNG 899
Query: 100 GSCQDSIWGYTCTCSPGYEGSNCE 123
G C ++C+C G CE
Sbjct: 900 GVCHSRWDDFSCSCPALTSGKACE 923
>gi|33667063 transmembrane protease, serine 9 [Homo sapiens]
Length = 1059
Score = 65.9 bits (159), Expect = 6e-11
Identities = 56/224 (25%), Positives = 94/224 (41%), Gaps = 22/224 (9%)
Query: 189 PWQVKLTNSEGKDFCGGVIIRENFVLTTAKCSLLHRNITVKTYFNRT----SQDPLMIKI 244
PWQV L + CG V++ E ++L+ A C ++ + F T + + ++
Sbjct: 839 PWQVSLWLRRREHRCGAVLVAERWLLSAAHCFDVYGDPKQWAAFLGTPFLSGAEGQLERV 898
Query: 245 THVHVHMRYDADAGENDLSLLELEWPIQCPGAGLPVCTPEKDFAEHLLIPR----TRGLL 300
++ H Y+ + D++LLEL P++ P+C PE PR TR ++
Sbjct: 899 ARIYKHPFYNLYTLDYDVALLELAGPVRRSRLVRPICLPEP-------APRPPDGTRCVI 951
Query: 301 SGW--ARNGTDLGNSLTTRPVTLVEGEECGQVLNVTVTTRTYCERSSVAAMHWMDGS--- 355
+GW R G + L V L+ + C + V +++R C + G
Sbjct: 952 TGWGSVREGGSMARQLQKAAVRLLSEQTCRRFYPVQISSRMLCAGFPQGGVDSCSGDAGG 1011
Query: 356 -VVTREHRGSWFLTGVLGSQPVGGQAHMV-LVTKVSRYSLWFKQ 397
+ RE G W LTGV G+ H + T+V+ W Q
Sbjct: 1012 PLACREPSGRWVLTGVTSWGYGCGRPHFPGVYTRVAAVRGWIGQ 1055
Score = 64.3 bits (155), Expect = 2e-10
Identities = 72/309 (23%), Positives = 123/309 (39%), Gaps = 46/309 (14%)
Query: 76 VVTDEFWRRYKGGSPCISQPCLHNGSCQDSIWGYTCTCSPGYEGSNCELAKNECHPERTD 135
+V+ E R+KG +++ +G C G + +C S C N PE D
Sbjct: 131 IVSAELTGRHKGP---LAERDFKSGRCP----GNSFSCG----NSQCVTKVN---PECDD 176
Query: 136 GCQHFCLPGQESYTCSCAQGYRLGEDHKQCVPHDQCACGVLTSEKRAPDLQDLPWQVKLT 195
Q C G + C C P + A ++ + +P + PWQ L
Sbjct: 177 --QEDCSDGSDEAHCECG-----------LQPAWRMAGRIVGGMEASPG--EFPWQASLR 221
Query: 196 NSEGKDFCGGVIIRENFVLTTAKCSLLHRNITV------KTYFNRTSQDPLMIKITHVHV 249
++ + FCG II ++++ A C ++ T TY + + + ++ +
Sbjct: 222 ENK-EHFCGAAIINARWLVSAAHCFNEFQDPTKWVAYVGATYLSGSEASTVRAQVVQIVK 280
Query: 250 HMRYDADAGENDLSLLELEWPIQCPGAGLPVCTPEKDFAEHLLIPRTRGLLSGWARNGTD 309
H Y+AD + D+++LEL P+ PVC P A H+ P + L+SGW D
Sbjct: 281 HPLYNADTADFDVAVLELTSPLPFGRHIQPVCLPA---ATHIFPPSKKCLISGWGYLKED 337
Query: 310 L---GNSLTTRPVTLVEGEECGQVLNVTVTTRTYC----ERSSVAAMHWMDGSVVTREHR 362
L V L++ C + ++T R C + + G +V E
Sbjct: 338 FLVKPEVLQKATVELLDQALCASLYGHSLTDRMVCAGYLDGKVDSCQGDSGGPLVCEEPS 397
Query: 363 GSWFLTGVL 371
G +FL G++
Sbjct: 398 GRFFLAGIV 406
Score = 57.8 bits (138), Expect = 2e-08
Identities = 54/229 (23%), Positives = 97/229 (42%), Gaps = 21/229 (9%)
Query: 187 DLPWQVKLTNSEGKDFCGGVIIRENFVLTTAKCSLLHRNITVKTYFNRTSQ-----DPLM 241
++PWQV L + FCG ++ + ++L+ A C + V+ + S P+
Sbjct: 514 EVPWQVSLKEGS-RHFCGATVVGDRWLLSAAHCFNHTKVEQVRAHLGTASLLGLGGSPVK 572
Query: 242 IKITHVHVHMRYDADAGENDLSLLELEWPIQCPGAGLPVCTPEKDFAEHLLIPRTRGLLS 301
I + V +H Y+ + DL++LEL P+ PVC P A + ++S
Sbjct: 573 IGLRRVVLHPLYNPGILDFDLAVLELASPLAFNKYIQPVCLP---LAIQKFPVGRKCMIS 629
Query: 302 GWARNGTDLGNS-----LTTRPVTLVEGEECGQVLNVTVTTRTYC----ERSSVAAMHWM 352
GW T GN+ L V +++ + C + N ++T R C E +
Sbjct: 630 GW--GNTQEGNATKPELLQKASVGIIDQKTCSVLYNFSLTDRMICAGFLEGKVDSCQGDS 687
Query: 353 DGSVVTREHRGSWFLTGVLGSQPVGGQAHMV-LVTKVSRYSLWFKQIMN 400
G + E G ++L G++ Q + T+++R W +IM+
Sbjct: 688 GGPLACEEAPGVFYLAGIVSWGIGCAQVKKPGVYTRITRLKGWILEIMS 736
>gi|78191798 plasma kallikrein B1 precursor [Homo sapiens]
Length = 638
Score = 65.5 bits (158), Expect = 8e-11
Identities = 63/271 (23%), Positives = 108/271 (39%), Gaps = 26/271 (9%)
Query: 143 PGQESYTCSCAQGYRLGEDHKQCVPHDQCACGVLTSEKRAPDLQ----DLPWQVKLTN-- 196
P + +Y + GY L + C D C TS + + PWQV L
Sbjct: 357 PTRIAYGTQGSSGYSL----RLCNTGDNSVCTTKTSTRIVGGTNSSWGEWPWQVSLQVKL 412
Query: 197 SEGKDFCGGVIIRENFVLTTAKC------SLLHRNITVKTYFNRTSQDPLMIKITHVHVH 250
+ + CGG +I +VLT A C + R + + ++D +I + +H
Sbjct: 413 TAQRHLCGGSLIGHQWVLTAAHCFDGLPLQDVWRIYSGILNLSDITKDTPFSQIKEIIIH 472
Query: 251 MRYDADAGENDLSLLELEWPIQCPGAGLPVCTPEKDFAEHLLIPRTRGLLSGW--ARNGT 308
Y G +D++L++L+ P+ P+C P K + T ++GW ++
Sbjct: 473 QNYKVSEGNHDIALIKLQAPLNYTEFQKPICLPSKGDTSTIY---TNCWVTGWGFSKEKG 529
Query: 309 DLGNSLTTRPVTLVEGEEC-GQVLNVTVTTRTYC---ERSSVAAMHWMDGSVVTREHRGS 364
++ N L + LV EEC + + +T R C + A G + +H G
Sbjct: 530 EIQNILQKVNIPLVTNEECQKRYQDYKITQRMVCAGYKEGGKDACKGDSGGPLVCKHNGM 589
Query: 365 WFLTGVLG-SQPVGGQAHMVLVTKVSRYSLW 394
W L G+ + + + TKV+ Y W
Sbjct: 590 WRLVGITSWGEGCARREQPGVYTKVAEYMDW 620
>gi|29244926 corin [Homo sapiens]
Length = 1042
Score = 65.5 bits (158), Expect = 8e-11
Identities = 56/204 (27%), Positives = 85/204 (41%), Gaps = 36/204 (17%)
Query: 189 PWQVKLTNSEGKDFCGGVIIRENFVLTTAKC-----------------SLLHRNITVKTY 231
PWQ L + CG V+I + +VLT A C +L H ++ ++T
Sbjct: 814 PWQCSLQSEPSGHICGCVLIAKKWVLTVAHCFEGRENAAVWKVVLGINNLDHPSVFMQTR 873
Query: 232 FNRTSQDPLMIKITHVHVHMRYDADAGENDLSLLELEWPIQCPGAGLPVCTPEKDFAEHL 291
F +T + +H RY + D+S++EL I G PVC P E
Sbjct: 874 FVKT-----------IILHPRYSRAVVDYDISIVELSEDISETGYVRPVCLPN---PEQW 919
Query: 292 LIPRTRGLLSGWARNGTDLGNSLTTRPVTLVEGEECGQVLNV-TVTTRTYC---ERSSV- 346
L P T ++GW G + L V ++ E C ++ T+TTR C E +V
Sbjct: 920 LEPDTYCYITGWGHMGNKMPFKLQEGEVRIISLEHCQSYFDMKTITTRMICAGYESGTVD 979
Query: 347 AAMHWMDGSVVTREHRGSWFLTGV 370
+ M G +V + G W L G+
Sbjct: 980 SCMGDSGGPLVCEKPGGRWTLFGL 1003
>gi|148833508 notch1 preproprotein [Homo sapiens]
Length = 2555
Score = 65.1 bits (157), Expect = 1e-10
Identities = 44/133 (33%), Positives = 58/133 (43%), Gaps = 26/133 (19%)
Query: 58 CYEEI----CVYEEAREVFENEVVTDEFWRRYKGGSPCISQPCLHNGSCQDSIWGYTCTC 113
C ++I C+ E EV TDE C S PCLHNG C D I + C C
Sbjct: 467 CLDQIGEFQCICMPGYEGVHCEVNTDE----------CASSPCLHNGRCLDKINEFQCEC 516
Query: 114 SPGYEGSNCELAKNECHPERTDGCQH--FCLPGQESYTCSCAQGY---RLGEDHKQCVP- 167
G+ G C+ +EC + C++ CL G +YTC C +GY D +C P
Sbjct: 517 PTGFTGHLCQYDVDEC---ASTPCKNGAKCLDGPNTYTCVCTEGYTGTHCEVDIDECDPD 573
Query: 168 ---HDQCACGVLT 177
+ C GV T
Sbjct: 574 PCHYGSCKDGVAT 586
Score = 61.2 bits (147), Expect = 2e-09
Identities = 32/89 (35%), Positives = 42/89 (47%), Gaps = 9/89 (10%)
Query: 91 CISQPCLHNGSCQDSIWGYTCTCSPGYEGSNCELAKNECHPERTDGCQH--FCLPGQESY 148
C+ PC H SCQ++ GY C C GY G NCE ++C P + C + C G +
Sbjct: 873 CVLSPCRHGASCQNTHGGYRCHCQAGYSGRNCETDIDDCRP---NPCHNGGSCTDGINTA 929
Query: 149 TCSCAQGYR---LGEDHKQCVPHDQCACG 174
C C G+R ED +C D C G
Sbjct: 930 FCDCLPGFRGTFCEEDINECA-SDPCRNG 957
Score = 60.5 bits (145), Expect = 3e-09
Identities = 28/68 (41%), Positives = 35/68 (51%), Gaps = 5/68 (7%)
Query: 91 CISQPCLHNGSCQDSIWGYTCTCSPGYEGSNCELAKNECHPERTDGCQH--FCLPGQESY 148
C C + G+C D I +TC C PG+ GS C+ NEC + C H C G SY
Sbjct: 987 CTESSCFNGGTCVDGINSFTCLCPPGFTGSYCQHDVNECD---SQPCLHGGTCQDGCGSY 1043
Query: 149 TCSCAQGY 156
C+C QGY
Sbjct: 1044 RCTCPQGY 1051
Score = 60.1 bits (144), Expect = 3e-09
Identities = 33/106 (31%), Positives = 47/106 (44%), Gaps = 9/106 (8%)
Query: 57 ECYEEICVYEEAREVFEN-EVVTDEFWRRYK---GGSPCISQPCLHNGSCQDSIWGYTCT 112
EC CV+ R+ + D W + C S PC++ G+C+D GY CT
Sbjct: 719 ECNSNPCVHGACRDSLNGYKCDCDPGWSGTNCDINNNECESNPCVNGGTCKDMTSGYVCT 778
Query: 113 CSPGYEGSNCELAKNECHPERTDGC--QHFCLPGQESYTCSCAQGY 156
C G+ G NC+ NEC ++ C Q C+ Y C+C Y
Sbjct: 779 CREGFSGPNCQTNINEC---ASNPCLNQGTCIDDVAGYKCNCLLPY 821
Score = 59.7 bits (143), Expect = 5e-09
Identities = 27/67 (40%), Positives = 36/67 (53%), Gaps = 4/67 (5%)
Query: 91 CISQPCLHNGSCQDSIWGYTCTCSPGYEGSNCELAKNECHPERTDGCQH-FCLPGQESYT 149
C S PC + C D YTC C+ GY G++CE+ +EC P D C + C G ++T
Sbjct: 532 CASTPCKNGAKCLDGPNTYTCVCTEGYTGTHCEVDIDECDP---DPCHYGSCKDGVATFT 588
Query: 150 CSCAQGY 156
C C GY
Sbjct: 589 CLCRPGY 595
Score = 59.7 bits (143), Expect = 5e-09
Identities = 31/71 (43%), Positives = 35/71 (49%), Gaps = 12/71 (16%)
Query: 91 CISQPCLHNGSCQDSIWGYTCTCSPGYEGSNC-----ELAKNECHPERTDGCQHFCLPGQ 145
C S PC +G+C D I GY C C PGY GS C E A N CH T C G
Sbjct: 645 CASSPC-DSGTCLDKIDGYECACEPGYTGSMCNINIDECAGNPCHNGGT------CEDGI 697
Query: 146 ESYTCSCAQGY 156
+TC C +GY
Sbjct: 698 NGFTCRCPEGY 708
Score = 59.3 bits (142), Expect = 6e-09
Identities = 27/66 (40%), Positives = 33/66 (50%), Gaps = 2/66 (3%)
Query: 91 CISQPCLHNGSCQDSIWGYTCTCSPGYEGSNCELAKNECHPERTDGCQHFCLPGQESYTC 150
C SQPC H G+CQD Y C C G G NCE+ ++C D CL + Y C
Sbjct: 607 CSSQPCRHGGTCQDRDNAYLCFCLKGTTGPNCEINLDDCASSPCD--SGTCLDKIDGYEC 664
Query: 151 SCAQGY 156
+C GY
Sbjct: 665 ACEPGY 670
Score = 59.3 bits (142), Expect = 6e-09
Identities = 28/68 (41%), Positives = 33/68 (48%), Gaps = 5/68 (7%)
Query: 91 CISQPCLHNGSCQDSIWGYTCTCSPGYEGSNCELAKNEC--HPERTDGCQHFCLPGQESY 148
C SQPCLH G+CQD Y CTC GY G NC+ + C P + G C Y
Sbjct: 1025 CDSQPCLHGGTCQDGCGSYRCTCPQGYTGPNCQNLVHWCDSSPCKNGG---KCWQTHTQY 1081
Query: 149 TCSCAQGY 156
C C G+
Sbjct: 1082 RCECPSGW 1089
Score = 57.8 bits (138), Expect = 2e-08
Identities = 25/68 (36%), Positives = 36/68 (52%), Gaps = 5/68 (7%)
Query: 91 CISQPCLHNGSCQDSIWGYTCTCSPGYEGSNCELAKNECHPERTDGCQH--FCLPGQESY 148
C+S PC ++ +C D I + C C PGYEG +CE+ +EC + C H CL +
Sbjct: 456 CVSNPCQNDATCLDQIGEFQCICMPGYEGVHCEVNTDEC---ASSPCLHNGRCLDKINEF 512
Query: 149 TCSCAQGY 156
C C G+
Sbjct: 513 QCECPTGF 520
Score = 57.4 bits (137), Expect = 2e-08
Identities = 26/66 (39%), Positives = 36/66 (54%), Gaps = 3/66 (4%)
Query: 93 SQPCLHNGSCQDSIWGYTCTCSPGYEGSNCELAKNEC--HPERTDGCQHFCLPGQESYTC 150
S C +NG+C D + GY+CTC PG+ G CE NEC +P G Q+ C+ + C
Sbjct: 1235 SPKCFNNGTCVDQVGGYSCTCPPGFVGERCEGDVNECLSNPCDARGTQN-CVQRVNDFHC 1293
Query: 151 SCAQGY 156
C G+
Sbjct: 1294 ECRAGH 1299
Score = 57.0 bits (136), Expect = 3e-08
Identities = 27/67 (40%), Positives = 35/67 (52%), Gaps = 6/67 (8%)
Query: 91 CISQPCLHNGSCQDSIWGYTCTCSPGYEGSNCELAKNECHPERTDGCQH--FCLPGQESY 148
C PC H GSC+D + +TC C PGY G +CE NEC + C+H C +Y
Sbjct: 570 CDPDPC-HYGSCKDGVATFTCLCRPGYTGHHCETNINEC---SSQPCRHGGTCQDRDNAY 625
Query: 149 TCSCAQG 155
C C +G
Sbjct: 626 LCFCLKG 632
Score = 55.8 bits (133), Expect = 7e-08
Identities = 26/67 (38%), Positives = 34/67 (50%), Gaps = 5/67 (7%)
Query: 91 CISQPCLHNGSCQDSIWGYTCTCSPGYEGSNCELAKNEC--HPERTDGCQHFCLPGQESY 148
C PC + +C D + GY+C C GY G NC +EC HP + G CL +Y
Sbjct: 1149 CSPSPCQNGATCTDYLGGYSCKCVAGYHGVNCSEEIDECLSHPCQNGGT---CLDLPNTY 1205
Query: 149 TCSCAQG 155
CSC +G
Sbjct: 1206 KCSCPRG 1212
Score = 53.9 bits (128), Expect = 2e-07
Identities = 24/67 (35%), Positives = 32/67 (47%), Gaps = 4/67 (5%)
Query: 91 CISQPCLHNGSCQDSIWGYTCTCSPGYEGSNCELAKNECHPERTDGCQH-FCLPGQESYT 149
C PC + G+C+D I G+TC C GY C NEC+ ++ C H C Y
Sbjct: 682 CAGNPCHNGGTCEDGINGFTCRCPEGYHDPTCLSEVNECN---SNPCVHGACRDSLNGYK 738
Query: 150 CSCAQGY 156
C C G+
Sbjct: 739 CDCDPGW 745
Score = 53.9 bits (128), Expect = 2e-07
Identities = 24/66 (36%), Positives = 34/66 (51%), Gaps = 1/66 (1%)
Query: 91 CISQPCLHNGSCQDSIWGYTCTCSPGYEGSNCELAKNECHPERTDGCQHFCLPGQESYTC 150
C S PC + +C D + YTCTC G+ G +CE +C E + C+ G S+TC
Sbjct: 949 CASDPCRNGANCTDCVDSYTCTCPAGFSGIHCENNTPDC-TESSCFNGGTCVDGINSFTC 1007
Query: 151 SCAQGY 156
C G+
Sbjct: 1008 LCPPGF 1013
Score = 53.1 bits (126), Expect = 4e-07
Identities = 30/104 (28%), Positives = 49/104 (47%), Gaps = 10/104 (9%)
Query: 91 CISQPCLHNGSCQDSIWGYTCTCSPGYEGSNCELAKNECHP-----ERTDGC--QHFCLP 143
C+S PC + G+C D Y C+C G +G +CE+ ++C+P R+ C C+
Sbjct: 1187 CLSHPCQNGGTCLDLPNTYKCSCPRGTQGVHCEINVDDCNPPVDPVSRSPKCFNNGTCVD 1246
Query: 144 GQESYTCSCAQGY---RLGEDHKQCVPHDQCACGVLTSEKRAPD 184
Y+C+C G+ R D +C+ + A G +R D
Sbjct: 1247 QVGGYSCTCPPGFVGERCEGDVNECLSNPCDARGTQNCVQRVND 1290
Score = 52.8 bits (125), Expect = 6e-07
Identities = 24/68 (35%), Positives = 35/68 (51%), Gaps = 1/68 (1%)
Query: 91 CISQPCLHNGSCQDSIWGYTCTCSPGYEGSNCELAKNECHPER-TDGCQHFCLPGQESYT 149
C S PCL+ G+C D + GY C C Y G+ CE+ C P +G + ES++
Sbjct: 795 CASNPCLNQGTCIDDVAGYKCNCLLPYTGATCEVVLAPCAPSPCRNGGECRQSEDYESFS 854
Query: 150 CSCAQGYR 157
C C G++
Sbjct: 855 CVCPTGWQ 862
Score = 50.1 bits (118), Expect = 4e-06
Identities = 27/82 (32%), Positives = 38/82 (46%), Gaps = 8/82 (9%)
Query: 92 ISQPCLHNGSCQDSIWGYTCTCSPGYEGSNCELAKNECHPERTDGCQH--FCLPGQESYT 149
+++ C H G C D+ + C C GY GS CE +EC P CQ+ C Y+
Sbjct: 1112 VARLCQHGGLCVDAGNTHHCRCQAGYTGSYCEDLVDECSP---SPCQNGATCTDYLGGYS 1168
Query: 150 CSCAQGY---RLGEDHKQCVPH 168
C C GY E+ +C+ H
Sbjct: 1169 CKCVAGYHGVNCSEEIDECLSH 1190
Score = 49.7 bits (117), Expect = 5e-06
Identities = 28/83 (33%), Positives = 40/83 (48%), Gaps = 10/83 (12%)
Query: 93 SQPCLHNGSCQDSIWGYTCTCSPGYEGSNCELAKNECHPERTDGCQH--FCLPGQESYTC 150
+ PC H G C +++ + C C GY G CE+ NEC ++ CQ+ CL + C
Sbjct: 420 ANPCEHAGKCINTLGSFECQCLQGYTGPRCEIDVNEC---VSNPCQNDATCLDQIGEFQC 476
Query: 151 SCAQGYRLGEDHKQC-VPHDQCA 172
C GY + C V D+CA
Sbjct: 477 ICMPGY----EGVHCEVNTDECA 495
Score = 49.7 bits (117), Expect = 5e-06
Identities = 24/72 (33%), Positives = 33/72 (45%), Gaps = 7/72 (9%)
Query: 89 SPCISQPCLHNGSCQDS--IWGYTCTCSPGYEGSNCELAKNECHPERTDGCQH--FCLPG 144
+PC PC + G C+ S ++C C G++G CE+ NEC C+H C
Sbjct: 831 APCAPSPCRNGGECRQSEDYESFSCVCPTGWQGQTCEVDINEC---VLSPCRHGASCQNT 887
Query: 145 QESYTCSCAQGY 156
Y C C GY
Sbjct: 888 HGGYRCHCQAGY 899
Score = 47.4 bits (111), Expect = 2e-05
Identities = 22/67 (32%), Positives = 34/67 (50%), Gaps = 3/67 (4%)
Query: 91 CISQPCLHNGSCQD-SIWGYTCTCSPGYEGSNCELAKNECHPERTDGCQHFCLPGQESYT 149
C++ PC + G+C ++ Y C C PG+ G +C+ A +G Q CLP + SY
Sbjct: 106 CLTNPCRNGGTCDLLTLTEYKCRCPPGWSGKSCQQADPCASNPCANGGQ--CLPFEASYI 163
Query: 150 CSCAQGY 156
C C +
Sbjct: 164 CHCPPSF 170
Score = 47.0 bits (110), Expect = 3e-05
Identities = 26/86 (30%), Positives = 33/86 (38%), Gaps = 3/86 (3%)
Query: 90 PCISQPCLHNGSCQDSIWGYTCTCSPGYEGSNCELAKNECHPERTDGCQH--FCLPGQES 147
PC S PC + G C Y C C P + G C NEC ++ C+H C S
Sbjct: 143 PCASNPCANGGQCLPFEASYICHCPPSFHGPTCRQDVNEC-GQKPGLCRHGGTCHNEVGS 201
Query: 148 YTCSCAQGYRLGEDHKQCVPHDQCAC 173
Y C C + + VP C
Sbjct: 202 YRCVCRATHTGPNCERPYVPCSPSPC 227
Score = 45.4 bits (106), Expect = 9e-05
Identities = 25/80 (31%), Positives = 36/80 (45%), Gaps = 5/80 (6%)
Query: 90 PCISQPCLHNGSCQDS-IWGYTCTCSPGYEGSNCELAKNECHPERTDGCQHFCLPGQESY 148
PC PC + G+C+ + + C C PG+ G NCE ++C P C+ G +Y
Sbjct: 221 PCSPSPCQNGGTCRPTGDVTHECACLPGFTGQNCEENIDDC-PGNNCKNGGACVDGVNTY 279
Query: 149 TCSCA---QGYRLGEDHKQC 165
C C G ED +C
Sbjct: 280 NCRCPPEWTGQYCTEDVDEC 299
Score = 43.9 bits (102), Expect = 3e-04
Identities = 26/84 (30%), Positives = 36/84 (42%), Gaps = 6/84 (7%)
Query: 91 CISQPCLHNGSCQDSIWGYTCTCSPGYEGSNCELAKNECHPERTDGCQH--FCLPGQESY 148
C C + G+C D + Y C C P + G C +EC + CQ+ C Y
Sbjct: 261 CPGNNCKNGGACVDGVNTYNCRCPPEWTGQYCTEDVDECQ-LMPNACQNGGTCHNTHGGY 319
Query: 149 TCSCAQGYRLGEDHKQCVPHDQCA 172
C C G+ GED + + D CA
Sbjct: 320 NCVCVNGW-TGEDCSENI--DDCA 340
Score = 42.7 bits (99), Expect = 6e-04
Identities = 22/75 (29%), Positives = 31/75 (41%), Gaps = 9/75 (12%)
Query: 91 CISQPCLHNGSCQDSIWGYTCTCSPGYEGSNCELAKNECH-PERTDG------CQH--FC 141
C S PC + G C + Y C C G+ G C++ C + G CQH C
Sbjct: 1063 CDSSPCKNGGKCWQTHTQYRCECPSGWTGLYCDVPSVSCEVAAQRQGVDVARLCQHGGLC 1122
Query: 142 LPGQESYTCSCAQGY 156
+ ++ C C GY
Sbjct: 1123 VDAGNTHHCRCQAGY 1137
Score = 42.0 bits (97), Expect = 0.001
Identities = 30/97 (30%), Positives = 42/97 (43%), Gaps = 15/97 (15%)
Query: 84 RYKGGSPCISQPCLHNGSC----QDSIWGYTCTCSPGYEGSNC-ELAKNEC--HPERTDG 136
R + +PC+S PC + G+C + + Y C+C+ G+ G C N C +P R G
Sbjct: 56 RCQDPNPCLSTPCKNAGTCHVVDRRGVADYACSCALGFSGPLCLTPLDNACLTNPCRNGG 115
Query: 137 -CQHFCLPGQESYTCSCAQGYRLGEDHKQCVPHDQCA 172
C L Y C C G+ K C D CA
Sbjct: 116 TCDLLTL---TEYKCRCPPGW----SGKSCQQADPCA 145
Score = 42.0 bits (97), Expect = 0.001
Identities = 22/67 (32%), Positives = 32/67 (47%), Gaps = 8/67 (11%)
Query: 91 CISQPCLHNGSC---QDSIWGYTCTCSPGYEGSNCELAKNECHPERTDGCQH--FCLPGQ 145
C +PC + G+C ++ G+ C C G+EG+ CE C R C + C+ G
Sbjct: 1311 CKGKPCKNGGTCAVASNTARGFICKCPAGFEGATCENDARTCGSLR---CLNGGTCISGP 1367
Query: 146 ESYTCSC 152
S TC C
Sbjct: 1368 RSPTCLC 1374
Score = 38.5 bits (88), Expect = 0.011
Identities = 26/88 (29%), Positives = 34/88 (38%), Gaps = 11/88 (12%)
Query: 91 CISQPCLHNGSCQDSIWGYTCTCSPGYEGSNCEL----AKNECHPERTDGCQHFCLPGQE 146
C S C H +C D + + C C G G C L N C+ +G P
Sbjct: 339 CASAACFHGATCHDRVASFYCECPHGRTGLLCHLNDACISNPCN----EGSNCDTNPVNG 394
Query: 147 SYTCSCAQGYRLGEDHKQCVPHDQCACG 174
C+C GY G Q V D+C+ G
Sbjct: 395 KAICTCPSGY-TGPACSQDV--DECSLG 419
Score = 36.2 bits (82), Expect = 0.054
Identities = 19/70 (27%), Positives = 27/70 (38%), Gaps = 4/70 (5%)
Query: 91 CISQPCLHNGS--CQDSIWGYTCTCSPGYEGSNCELAKNEC--HPERTDGCQHFCLPGQE 146
C+S PC G+ C + + C C G+ G CE N C P + G
Sbjct: 1271 CLSNPCDARGTQNCVQRVNDFHCECRAGHTGRRCESVINGCKGKPCKNGGTCAVASNTAR 1330
Query: 147 SYTCSCAQGY 156
+ C C G+
Sbjct: 1331 GFICKCPAGF 1340
Score = 35.8 bits (81), Expect = 0.070
Identities = 24/73 (32%), Positives = 31/73 (42%), Gaps = 7/73 (9%)
Query: 90 PCISQP---CLHNGSCQDSIWGYTCTCSPGYEGSNCELAKNEC--HPERTDG-CQHFCLP 143
P SQP CL+ G C+ + C C + G C+ N C P + G C
Sbjct: 22 PRCSQPGETCLNGGKCEAANGTEACVCGGAFVGPRCQ-DPNPCLSTPCKNAGTCHVVDRR 80
Query: 144 GQESYTCSCAQGY 156
G Y CSCA G+
Sbjct: 81 GVADYACSCALGF 93
Score = 32.3 bits (72), Expect = 0.78
Identities = 22/71 (30%), Positives = 28/71 (39%), Gaps = 15/71 (21%)
Query: 91 CISQPCLHNGSCQDSIWGYTCTCSPGYEGSNCE-------LAKNECHPERTDGCQHFCLP 143
C S CL+ G+C TC C + G C+ L N C+ + T C P
Sbjct: 1352 CGSLRCLNGGTCISGPRSPTCLCLGPFTGPECQFPASSPCLGGNPCYNQGT------CEP 1405
Query: 144 GQES--YTCSC 152
ES Y C C
Sbjct: 1406 TSESPFYRCLC 1416
>gi|24041035 notch 2 preproprotein [Homo sapiens]
Length = 2471
Score = 64.3 bits (155), Expect = 2e-10
Identities = 31/84 (36%), Positives = 47/84 (55%), Gaps = 9/84 (10%)
Query: 91 CISQPCLHNGSCQDSIWGYTCTCSPGYEGSNCELAKNECHPERTDGCQH-FCLPGQESYT 149
C S PCL++G C D + GY C C PG G NCE+ ++C ++ C H C+ G Y+
Sbjct: 611 CYSSPCLNDGRCIDLVNGYQCNCQPGTSGVNCEINFDDC---ASNPCIHGICMDGINRYS 667
Query: 150 CSCAQGYRLGEDHKQC-VPHDQCA 172
C C+ G+ ++C + D+CA
Sbjct: 668 CVCSPGF----TGQRCNIDIDECA 687
Score = 64.3 bits (155), Expect = 2e-10
Identities = 35/82 (42%), Positives = 41/82 (50%), Gaps = 8/82 (9%)
Query: 91 CISQPCLHNGSCQDSIWGYTCTCSPGYEGSNCELAKNECHP---ERTDGCQHFCLPGQES 147
C S PCL+ G+C D I GYTC C Y G NC+ C P E C+ P ES
Sbjct: 799 CASNPCLNQGTCFDDISGYTCHCVLPYTGKNCQTVLAPCSPNPCENAAVCKE--SPNFES 856
Query: 148 YTCSCA---QGYRLGEDHKQCV 166
YTC CA QG R D +C+
Sbjct: 857 YTCLCAPGWQGQRCTIDIDECI 878
Score = 63.5 bits (153), Expect = 3e-10
Identities = 29/69 (42%), Positives = 36/69 (52%), Gaps = 5/69 (7%)
Query: 91 CISQPCLHNGSCQDSIWGYTCTCSPGYEGSNCELAKNECHPERTDGCQH--FCLPGQESY 148
C S PC H +C D I GY C C PGY+G NCE +EC + CQ+ C+ +
Sbjct: 1153 CASNPCQHGATCSDFIGGYRCECVPGYQGVNCEYEVDEC---QNQPCQNGGTCIDLVNHF 1209
Query: 149 TCSCAQGYR 157
CSC G R
Sbjct: 1210 KCSCPPGTR 1218
Score = 60.1 bits (144), Expect = 3e-09
Identities = 32/90 (35%), Positives = 48/90 (53%), Gaps = 9/90 (10%)
Query: 85 YKGGSPCISQPCLHNGSCQDSIWGYTCTCSPGYEGSNCELAKNECHPERTDGCQH--FCL 142
Y + C+S PC+H G+C + GY C C G+ G NCE+ KNEC ++ CQ+ C
Sbjct: 718 YSQVNECLSNPCIH-GNCTGGLSGYKCLCDAGWVGINCEVDKNEC---LSNPCQNGGTCD 773
Query: 143 PGQESYTCSCAQGYRLGEDHKQCVPHDQCA 172
Y C+C +G++ + V D+CA
Sbjct: 774 NLVNGYRCTCKKGFK---GYNCQVNIDECA 800
Score = 58.5 bits (140), Expect = 1e-08
Identities = 29/67 (43%), Positives = 34/67 (50%), Gaps = 4/67 (5%)
Query: 91 CISQPCLHNGSCQDSIWGYTCTCSPGYEGSNCELAKNECHPERTDGCQHF-CLPGQESYT 149
C S PCL+ C D GY C C+ G+ G CE + C P D C H C G +SYT
Sbjct: 536 CSSTPCLNGAKCIDHPNGYECQCATGFTGVLCEENIDNCDP---DPCHHGQCQDGIDSYT 592
Query: 150 CSCAQGY 156
C C GY
Sbjct: 593 CICNPGY 599
Score = 58.5 bits (140), Expect = 1e-08
Identities = 25/68 (36%), Positives = 35/68 (51%), Gaps = 5/68 (7%)
Query: 91 CISQPCLHNGSCQDSIWGYTCTCSPGYEGSNCELAKNEC--HPERTDGCQHFCLPGQESY 148
C++ PC + GSC D + ++C C PG+ G C+ NEC P + G C SY
Sbjct: 915 CLANPCQNGGSCMDGVNTFSCLCLPGFTGDKCQTDMNECLSEPCKNGGT---CSDYVNSY 971
Query: 149 TCSCAQGY 156
TC C G+
Sbjct: 972 TCKCQAGF 979
Score = 58.5 bits (140), Expect = 1e-08
Identities = 25/66 (37%), Positives = 38/66 (57%), Gaps = 1/66 (1%)
Query: 91 CISQPCLHNGSCQDSIWGYTCTCSPGYEGSNCELAKNECHPERTDGCQHFCLPGQESYTC 150
C+S+PC + G+C D + YTC C G++G +CE NEC E + C+ G S++C
Sbjct: 953 CLSEPCKNGGTCSDYVNSYTCKCQAGFDGVHCENNINEC-TESSCFNGGTCVDGINSFSC 1011
Query: 151 SCAQGY 156
C G+
Sbjct: 1012 LCPVGF 1017
Score = 57.8 bits (138), Expect = 2e-08
Identities = 25/68 (36%), Positives = 37/68 (54%), Gaps = 5/68 (7%)
Query: 91 CISQPCLHNGSCQDSIWGYTCTCSPGYEGSNCELAKNECHPERTDGC--QHFCLPGQESY 148
C+S PC + G+C + + GY CTC G++G NC++ +EC ++ C Q C Y
Sbjct: 761 CLSNPCQNGGTCDNLVNGYRCTCKKGFKGYNCQVNIDEC---ASNPCLNQGTCFDDISGY 817
Query: 149 TCSCAQGY 156
TC C Y
Sbjct: 818 TCHCVLPY 825
Score = 57.0 bits (136), Expect = 3e-08
Identities = 25/68 (36%), Positives = 39/68 (57%), Gaps = 5/68 (7%)
Query: 91 CISQPCLHNGSCQDSIWGYTCTCSPGYEGSNCELAKNECHPERTDGCQH--FCLPGQESY 148
C S PC ++ +C D I G+TC C PG++G +CEL NEC +++ C + C+ +
Sbjct: 460 CHSDPCQNDATCLDKIGGFTCLCMPGFKGVHCELEINEC---QSNPCVNNGQCVDKVNRF 516
Query: 149 TCSCAQGY 156
C C G+
Sbjct: 517 QCLCPPGF 524
Score = 56.6 bits (135), Expect = 4e-08
Identities = 23/68 (33%), Positives = 40/68 (58%), Gaps = 5/68 (7%)
Query: 91 CISQPCLHNGSCQDSIWGYTCTCSPGYEGSNCELAKNECHPERTDGCQH--FCLPGQESY 148
CIS+PC+++G C ++ Y C C PG+ G +CE ++C + CQ+ C+ G ++
Sbjct: 877 CISKPCMNHGLCHNTQGSYMCECPPGFSGMDCEEDIDDC---LANPCQNGGSCMDGVNTF 933
Query: 149 TCSCAQGY 156
+C C G+
Sbjct: 934 SCLCLPGF 941
Score = 55.8 bits (133), Expect = 7e-08
Identities = 26/67 (38%), Positives = 35/67 (52%), Gaps = 5/67 (7%)
Query: 93 SQPCLHNGSCQDSIWGYTCTCSPGYEGSNCELAKNECHPERTDGCQH--FCLPGQESYTC 150
S PC H G C ++ + C C GY G CE+ NECH +D CQ+ CL +TC
Sbjct: 424 SNPCEHAGKCVNTDGAFHCECLKGYAGPRCEMDINECH---SDPCQNDATCLDKIGGFTC 480
Query: 151 SCAQGYR 157
C G++
Sbjct: 481 LCMPGFK 487
Score = 55.8 bits (133), Expect = 7e-08
Identities = 29/93 (31%), Positives = 44/93 (47%), Gaps = 10/93 (10%)
Query: 91 CISQPCLHNGSCQDSIWGYTCTCSPGYEGSNCELAKNECHPER-TDGCQHFCLPGQESYT 149
C S PC++NG C D + + C C PG+ G C++ ++C +G + C+ Y
Sbjct: 498 CQSNPCVNNGQCVDKVNRFQCLCPPGFTGPVCQIDIDDCSSTPCLNGAK--CIDHPNGYE 555
Query: 150 CSCAQGYR---LGEDHKQCVP----HDQCACGV 175
C CA G+ E+ C P H QC G+
Sbjct: 556 CQCATGFTGVLCEENIDNCDPDPCHHGQCQDGI 588
Score = 55.5 bits (132), Expect = 9e-08
Identities = 29/83 (34%), Positives = 42/83 (50%), Gaps = 9/83 (10%)
Query: 90 PCISQPCLHNGSC-QDSIWGYTCTCSPGYEGSNCELAKNECHPERTDGCQH--FCLPGQE 146
PC PC++ G+C Q + + C C PG+EGS CE ++C R CQ+ C+ G
Sbjct: 224 PCAPSPCVNGGTCRQTGDFTFECNCLPGFEGSTCERNIDDCPNHR---CQNGGVCVDGVN 280
Query: 147 SYTCSCA---QGYRLGEDHKQCV 166
+Y C C G ED +C+
Sbjct: 281 TYNCRCPPQWTGQFCTEDVDECL 303
Score = 54.7 bits (130), Expect = 1e-07
Identities = 28/67 (41%), Positives = 35/67 (52%), Gaps = 6/67 (8%)
Query: 91 CISQPCLHNGSCQDSIWGYTCTCSPGYEGSNCELAKNECH--PERTDGCQHFCLPGQESY 148
C PC H+G CQD I YTC C+PGY G+ C +EC+ P DG C+ Y
Sbjct: 574 CDPDPC-HHGQCQDGIDSYTCICNPGYMGAICSDQIDECYSSPCLNDG---RCIDLVNGY 629
Query: 149 TCSCAQG 155
C+C G
Sbjct: 630 QCNCQPG 636
Score = 53.9 bits (128), Expect = 2e-07
Identities = 26/68 (38%), Positives = 34/68 (50%), Gaps = 5/68 (7%)
Query: 91 CISQPCLHNGSCQDSIWGYTCTCSPGYEGSNCELAKNEC--HPERTDGCQHFCLPGQESY 148
C C + G+C D I ++C C G+ GS C NEC HP +G C+ G +Y
Sbjct: 991 CTESSCFNGGTCVDGINSFSCLCPVGFTGSFCLHEINECSSHPCLNEGT---CVDGLGTY 1047
Query: 149 TCSCAQGY 156
CSC GY
Sbjct: 1048 RCSCPLGY 1055
Score = 52.8 bits (125), Expect = 6e-07
Identities = 25/68 (36%), Positives = 33/68 (48%), Gaps = 4/68 (5%)
Query: 91 CISQPCLHNGSCQDSIWGYTCTCSPGYEGSNCELAKNECHPERTDGCQH--FCLPGQESY 148
C+S PC + +C ++C C G+ G CE NEC + CQH CL SY
Sbjct: 148 CLSHPCANGSTCTTVANQFSCKCLTGFTGQKCETDVNEC--DIPGHCQHGGTCLNLPGSY 205
Query: 149 TCSCAQGY 156
C C QG+
Sbjct: 206 QCQCPQGF 213
Score = 52.0 bits (123), Expect = 9e-07
Identities = 24/63 (38%), Positives = 32/63 (50%), Gaps = 3/63 (4%)
Query: 96 CLHNGSCQDSIWGYTCTCSPGYEGSNCELAKNEC--HPERTDGCQHFCLPGQESYTCSCA 153
CL+ G C D I GY+C C PG+ G CE NEC +P ++G C+ Y C C
Sbjct: 1235 CLNGGQCMDRIGGYSCRCLPGFAGERCEGDINECLSNPCSSEGSLD-CIQLTNDYLCVCR 1293
Query: 154 QGY 156
+
Sbjct: 1294 SAF 1296
Score = 51.6 bits (122), Expect = 1e-06
Identities = 24/68 (35%), Positives = 33/68 (48%), Gaps = 5/68 (7%)
Query: 91 CISQPCLHNGSCQDSIWGYTCTCSPGYEGSNCELAKNEC--HPERTDGCQHFCLPGQESY 148
C S PCL+ G+C D + Y C+C GY G NC+ N C P + G C+ +
Sbjct: 1029 CSSHPCLNEGTCVDGLGTYRCSCPLGYTGKNCQTLVNLCSRSPCKNKGT---CVQKKAES 1085
Query: 149 TCSCAQGY 156
C C G+
Sbjct: 1086 QCLCPSGW 1093
Score = 50.4 bits (119), Expect = 3e-06
Identities = 23/70 (32%), Positives = 35/70 (50%), Gaps = 4/70 (5%)
Query: 91 CISQPCLHNGSCQDSIWG--YTCTCSPGYEGSNCELAKNECHPERTDGCQHF--CLPGQE 146
CIS PC C + Y CTC GY+G++C +EC ++ C+H C+
Sbjct: 379 CISNPCHKGALCDTNPLNGQYICTCPQGYKGADCTEDVDECAMANSNPCEHAGKCVNTDG 438
Query: 147 SYTCSCAQGY 156
++ C C +GY
Sbjct: 439 AFHCECLKGY 448
Score = 49.3 bits (116), Expect = 6e-06
Identities = 25/72 (34%), Positives = 35/72 (48%), Gaps = 7/72 (9%)
Query: 89 SPCISQPCLHNGSCQDS--IWGYTCTCSPGYEGSNCELAKNEC--HPERTDGCQHFCLPG 144
+PC PC + C++S YTC C+PG++G C + +EC P G C
Sbjct: 835 APCSPNPCENAAVCKESPNFESYTCLCAPGWQGQRCTIDIDECISKPCMNHG---LCHNT 891
Query: 145 QESYTCSCAQGY 156
Q SY C C G+
Sbjct: 892 QGSYMCECPPGF 903
Score = 47.4 bits (111), Expect = 2e-05
Identities = 26/81 (32%), Positives = 40/81 (49%), Gaps = 7/81 (8%)
Query: 91 CISQPCLHNGSCQDSIWGYTCTCSPGYEGSNCELAKNEC--HPERTDGCQHFCLPGQESY 148
C +QPC + G+C D + + C+C PG G CE ++C P +G Q C+ Y
Sbjct: 1191 CQNQPCQNGGTCIDLVNHFKCSCPPGTRGLLCEENIDDCARGPHCLNGGQ--CMDRIGGY 1248
Query: 149 TCSCAQGY---RLGEDHKQCV 166
+C C G+ R D +C+
Sbjct: 1249 SCRCLPGFAGERCEGDINECL 1269
Score = 43.5 bits (101), Expect = 3e-04
Identities = 23/64 (35%), Positives = 31/64 (48%), Gaps = 5/64 (7%)
Query: 96 CLHNGSCQDSIWGYTCTCSPGYEGSNCELAKNECHPERTDGCQH--FCLPGQESYTCSCA 153
C H+G C ++ + C C GY GS CE +EC ++ CQH C Y C C
Sbjct: 1120 CQHSGVCINAGNTHYCQCPLGYTGSYCEEQLDEC---ASNPCQHGATCSDFIGGYRCECV 1176
Query: 154 QGYR 157
GY+
Sbjct: 1177 PGYQ 1180
Score = 43.1 bits (100), Expect = 4e-04
Identities = 26/82 (31%), Positives = 36/82 (43%), Gaps = 18/82 (21%)
Query: 84 RYKGGSPC-ISQPCLHNGSCQD-SIWGYTCTCSPGYEGSNCELAKNECHPERTDGC-QHF 140
+Y PC +S+PCL+ G+C S Y CTC G+ G C+ TD C H
Sbjct: 102 QYSTSHPCFVSRPCLNGGTCHMLSRDTYECTCQVGFTGKECQW---------TDACLSHP 152
Query: 141 CLPGQ------ESYTCSCAQGY 156
C G ++C C G+
Sbjct: 153 CANGSTCTTVANQFSCKCLTGF 174
Score = 42.4 bits (98), Expect = 8e-04
Identities = 21/67 (31%), Positives = 29/67 (43%), Gaps = 4/67 (5%)
Query: 91 CISQPCLHNGSCQDSIWGYTCTCSPGYEGSNCELAKNECHPERTDGCQH-FCLPGQESYT 149
C S PC +C + + G+ C C G +C NEC ++ C H C G Y
Sbjct: 686 CASNPCRKGATCINGVNGFRCICPEGPHHPSCYSQVNEC---LSNPCIHGNCTGGLSGYK 742
Query: 150 CSCAQGY 156
C C G+
Sbjct: 743 CLCDAGW 749
Score = 42.0 bits (97), Expect = 0.001
Identities = 29/86 (33%), Positives = 37/86 (43%), Gaps = 11/86 (12%)
Query: 91 CISQPCLHNGSCQDSIWGYTCTCSPGYEGSNCEL----AKNECHPERTDGCQHFCLPGQE 146
C C +C D + ++C C G G C L N CH C L GQ
Sbjct: 342 CAFASCTPGSTCIDRVASFSCMCPEGKAGLLCHLDDACISNPCHKGAL--CDTNPLNGQ- 398
Query: 147 SYTCSCAQGYRLGEDHKQCVPHDQCA 172
Y C+C QGY+ G D + V D+CA
Sbjct: 399 -YICTCPQGYK-GADCTEDV--DECA 420
Score = 42.0 bits (97), Expect = 0.001
Identities = 19/38 (50%), Positives = 22/38 (57%), Gaps = 2/38 (5%)
Query: 89 SPCISQPCLHNGSC--QDSIWGYTCTCSPGYEGSNCEL 124
S C S PC H GSC Q Y+C C+P + GS CEL
Sbjct: 1376 SGCASSPCQHGGSCHPQRQPPYYSCQCAPPFSGSRCEL 1413
Score = 41.6 bits (96), Expect = 0.001
Identities = 25/84 (29%), Positives = 37/84 (44%), Gaps = 6/84 (7%)
Query: 91 CISQPCLHNGSCQDSIWGYTCTCSPGYEGSNCELAKNECHPERTDGCQH--FCLPGQESY 148
C + C + G C D + Y C C P + G C +EC + + CQ+ C Y
Sbjct: 264 CPNHRCQNGGVCVDGVNTYNCRCPPQWTGQFCTEDVDECLLQ-PNACQNGGTCANRNGGY 322
Query: 149 TCSCAQGYRLGEDHKQCVPHDQCA 172
C C G+ G+D + + D CA
Sbjct: 323 GCVCVNGWS-GDDCSENI--DDCA 343
Score = 39.7 bits (91), Expect = 0.005
Identities = 26/96 (27%), Positives = 38/96 (39%), Gaps = 14/96 (14%)
Query: 91 CISQPCLHNGSC---QDSIWGYTCTCSPGYEGSNCELAKNECHPERTDGCQH-------F 140
C PCL+ G+C + G+ C C PG+ G+ C+ + + + + C H F
Sbjct: 1308 CPQMPCLNGGTCAVASNMPDGFICRCPPGFSGARCQSSCGQVKCRKGEQCVHTASGPRCF 1367
Query: 141 CLPGQESYTCSCAQG--YRLGEDHKQ-CVPHDQCAC 173
C P CA G H Q P+ C C
Sbjct: 1368 C-PSPRDCESGCASSPCQHGGSCHPQRQPPYYSCQC 1402
Score = 38.9 bits (89), Expect = 0.008
Identities = 31/101 (30%), Positives = 38/101 (37%), Gaps = 18/101 (17%)
Query: 96 CLHNGSCQDSIWGYTCTCSPGYEGSNCELAKNECHPE--------RTDGCQHF---CLPG 144
C H G+C + Y C C G+ G C+ C P R G F CLPG
Sbjct: 192 CQHGGTCLNLPGSYQCQCPQGFTGQYCDSLYVPCAPSPCVNGGTCRQTGDFTFECNCLPG 251
Query: 145 QESYTCSCAQGYRLGED--HKQCVPHDQCACGVLTSEKRAP 183
E TC R +D + +C C GV T R P
Sbjct: 252 FEGSTCE-----RNIDDCPNHRCQNGGVCVDGVNTYNCRCP 287
Score = 38.1 bits (87), Expect = 0.014
Identities = 23/88 (26%), Positives = 39/88 (44%), Gaps = 12/88 (13%)
Query: 90 PCISQPCLHNGSC--QDSIWGYTCTCSPGYEGSNCELAKNE----CHPERTDGCQHFCLP 143
PC C + G+C Q + TC C+ G+ G +C+ + + P G H +
Sbjct: 67 PCEKNRCQNGGTCVAQAMLGKATCRCASGFTGEDCQYSTSHPCFVSRPCLNGGTCH--ML 124
Query: 144 GQESYTCSCAQGYRLGEDHKQCVPHDQC 171
+++Y C+C G+ K+C D C
Sbjct: 125 SRDTYECTCQVGF----TGKECQWTDAC 148
Score = 38.1 bits (87), Expect = 0.014
Identities = 23/91 (25%), Positives = 35/91 (38%), Gaps = 12/91 (13%)
Query: 91 CISQPCLHNGSCQDSIWGYTCTCSPGYEGSNCELAKNECHPERTDG-------CQH--FC 141
C PC + G+C C C G+ G+ C++ C + CQH C
Sbjct: 1067 CSRSPCKNKGTCVQKKAESQCLCPSGWAGAYCDVPNVSCDIAASRRGVLVEHLCQHSGVC 1126
Query: 142 LPGQESYTCSCAQGYRLGEDHKQCVPHDQCA 172
+ ++ C C GY +Q D+CA
Sbjct: 1127 INAGNTHYCQCPLGYTGSYCEEQL---DECA 1154
Score = 33.5 bits (75), Expect = 0.35
Identities = 20/79 (25%), Positives = 27/79 (34%), Gaps = 4/79 (5%)
Query: 91 CISQPCLHNGS--CQDSIWGYTCTCSPGYEGSNCELAKNEC--HPERTDGCQHFCLPGQE 146
C+S PC GS C Y C C + G +CE + C P G +
Sbjct: 1268 CLSNPCSSEGSLDCIQLTNDYLCVCRSAFTGRHCETFVDVCPQMPCLNGGTCAVASNMPD 1327
Query: 147 SYTCSCAQGYRLGEDHKQC 165
+ C C G+ C
Sbjct: 1328 GFICRCPPGFSGARCQSSC 1346
>gi|62526043 chymotrypsin C preproprotein [Homo sapiens]
Length = 268
Score = 62.8 bits (151), Expect = 5e-10
Identities = 59/229 (25%), Positives = 97/229 (42%), Gaps = 22/229 (9%)
Query: 189 PWQVKLT---NSEGKDFCGGVIIRENFVLTTAKCSLLHRNITVKTYFNRTS----QDPLM 241
PWQ+ L N + CGG +I NFVLT A C R V N + L
Sbjct: 42 PWQISLQYLKNDTWRHTCGGTLIASNFVLTAAHCISNTRTYRVAVGKNNLEVEDEEGSLF 101
Query: 242 IKITHVHVHMRYDADAGENDLSLLELEWPIQCPGAGLPVCTPEKDFAEHLLIPRTRG-LL 300
+ + +HVH R++A ND++L++L ++ C PEKD L+P+ +
Sbjct: 102 VGVDTIHVHKRWNALLLRNDIALIKLAEHVELSDTIQVACLPEKD----SLLPKDYPCYV 157
Query: 301 SGWARNGTD--LGNSLTTRPVTLVEGEECGQV----LNVTVTTRTYCERSSVAAMHWMDG 354
+GW R T+ + + L +V+ C ++ V T ++A + G
Sbjct: 158 TGWGRLWTNGPIADKLQQGLQPVVDHATCSRIDWWGFRVKKTMVCAGGDGVISACNGDSG 217
Query: 355 SVVTRE-HRGSWFLTGVLGSQPVGG---QAHMVLVTKVSRYSLWFKQIM 399
+ + GSW + G++ G + V+ T+VS Y W + M
Sbjct: 218 GPLNCQLENGSWEVFGIVSFGSRRGCNTRKKPVVYTRVSAYIDWINEKM 266
>gi|110578663 hypothetical protein LOC203074 [Homo sapiens]
Length = 352
Score = 62.8 bits (151), Expect = 5e-10
Identities = 55/231 (23%), Positives = 103/231 (44%), Gaps = 23/231 (9%)
Query: 184 DLQDLPWQVKLTNSEGKDFCGGVIIRENFVLTTAKC----SLLHRNITVKTYFNRTSQDP 239
++ + PWQV + + + FCGG I+ + ++LT A C L ++V N +
Sbjct: 75 EVGEFPWQVSI-QARSEPFCGGSILNKWWILTAAHCLYSEELFPEELSVVLGTNDLTSPS 133
Query: 240 LMIK-ITHVHVHMRYDADAGENDLSLLELEWPIQCPGAGLPVCTPEKDFAEHLLIPRT-- 296
+ IK + + +H + +ND++LL L PI+ +P+C P + P T
Sbjct: 134 MEIKEVASIILHKDFKRANMDNDIALLLLASPIKLDDLKVPICLPTQPG------PATWR 187
Query: 297 RGLLSGWARNGTDLGNSLTT----RPVTLVEGEECGQV---LNVTVTTRTYCERSSVAAM 349
++GW + NS+ T P+ +++ EEC ++ L + Y S A
Sbjct: 188 ECWVAGWGQTNAADKNSVKTDLMKAPMVIMDWEECSKMFPKLTKNMLCAGYKNESYDACK 247
Query: 350 HWMDGSVV-TREHRGSWFLTGVLG-SQPVGGQAHMVLVTKVSRYSLWFKQI 398
G +V T E W+ G++ + G + + T + Y+LW +++
Sbjct: 248 GDSGGPLVCTPEPGEKWYQVGIISWGKSCGEKNTPGIYTSLVNYNLWIEKV 298
>gi|10190748 CEGP1 protein [Homo sapiens]
Length = 999
Score = 62.4 bits (150), Expect = 7e-10
Identities = 30/78 (38%), Positives = 40/78 (51%), Gaps = 3/78 (3%)
Query: 96 CLHNGSCQDSIWGYTCTCSPGY--EGSNCELAKNECHPERTDGCQHFCLPGQESYTCSCA 153
C + CQ++ Y C+C PGY EG CE +EC E GC H CL +Y C+C
Sbjct: 56 CHADALCQNTPTSYKCSCKPGYQGEGRQCEDI-DECGNELNGGCVHDCLNIPGNYRCTCF 114
Query: 154 QGYRLGEDHKQCVPHDQC 171
G+ L D C+ D+C
Sbjct: 115 DGFMLAHDGHNCLDVDEC 132
Score = 53.1 bits (126), Expect = 4e-07
Identities = 26/76 (34%), Positives = 40/76 (52%), Gaps = 6/76 (7%)
Query: 101 SCQDSIWGYTCTCSPGY----EGSNCELAKNECHPERTDGCQHFCLPGQESYTCSCAQGY 156
+C+D+ G C+C G+ +G C+ +EC R GC HFC S+ C C +G+
Sbjct: 296 TCKDTSTGVHCSCPVGFTLQLDGKTCKDI-DECQT-RNGGCDHFCKNIVGSFDCGCKKGF 353
Query: 157 RLGEDHKQCVPHDQCA 172
+L D K C D+C+
Sbjct: 354 KLLTDEKSCQDVDECS 369
Score = 51.2 bits (121), Expect = 2e-06
Identities = 27/75 (36%), Positives = 39/75 (52%), Gaps = 8/75 (10%)
Query: 96 CLHNGSCQDSIWGYTCTCSPGY----EGSNCELAKNECHPERTDGCQHFCLPGQESYTCS 151
C+H+ C + Y CTC G+ +G NC L +EC E GCQH C+ SY C
Sbjct: 98 CVHD--CLNIPGNYRCTCFDGFMLAHDGHNC-LDVDECL-ENNGGCQHTCVNVMGSYECC 153
Query: 152 CAQGYRLGEDHKQCV 166
C +G+ L ++ C+
Sbjct: 154 CKEGFFLSDNQHTCI 168
Score = 41.2 bits (95), Expect = 0.002
Identities = 26/78 (33%), Positives = 36/78 (46%), Gaps = 7/78 (8%)
Query: 92 ISQPCLHNGSCQDSIWGYTCTCSPGYE---GSNCELAKNECHPERTDGCQHFCLPGQESY 148
+ + C H SC + + C C+ GY ++C NEC GCQ C+ SY
Sbjct: 370 LDRTCDH--SCINHPGTFACACNRGYTLYGFTHCG-DTNECSINN-GGCQQVCVNTVGSY 425
Query: 149 TCSCAQGYRLGEDHKQCV 166
C C GY+L + K CV
Sbjct: 426 ECQCHPGYKLHWNKKDCV 443
Score = 40.0 bits (92), Expect = 0.004
Identities = 28/102 (27%), Positives = 45/102 (44%), Gaps = 13/102 (12%)
Query: 84 RYKGGSPCISQPCLHNGSCQDSIWG-YTCTCSPGYEGSNCELAKNE------CHPERTDG 136
R + G C+++ + C+++ G C C PG+E LAKN+ C+ G
Sbjct: 170 RSEEGLSCMNKDHGCSHICKEAPRGSVACECRPGFE-----LAKNQRDCILTCN-HGNGG 223
Query: 137 CQHFCLPGQESYTCSCAQGYRLGEDHKQCVPHDQCACGVLTS 178
CQH C + CSC Y++ D + C+ + V S
Sbjct: 224 CQHSCDDTADGPECSCHPQYKMHTDGRSCLEREDTVLEVTES 265
Score = 34.3 bits (77), Expect = 0.20
Identities = 28/107 (26%), Positives = 37/107 (34%), Gaps = 34/107 (31%)
Query: 96 CLHNGSCQDSIWGYTCTCSPGY----EGSNCELAKNECHPERTD---------------- 135
C H SC D+ G C+C P Y +G +C L + + E T+
Sbjct: 224 CQH--SCDDTADGPECSCHPQYKMHTDGRSC-LEREDTVLEVTESNTTSVVDGDKRVKRR 280
Query: 136 -----------GCQHFCLPGQESYTCSCAQGYRLGEDHKQCVPHDQC 171
GC C CSC G+ L D K C D+C
Sbjct: 281 LLMETCAVNNGGCDRTCKDTSTGVHCSCPVGFTLQLDGKTCKDIDEC 327
Database: hs.faa
Posted date: Aug 4, 2009 4:42 PM
Number of letters in database: 18,247,518
Number of sequences in database: 37,866
Lambda K H
0.320 0.136 0.444
Gapped
Lambda K H
0.267 0.0410 0.140
Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Hits to DB: 17,402,005
Number of Sequences: 37866
Number of extensions: 858292
Number of successful extensions: 4202
Number of sequences better than 10.0: 30
Number of HSP's better than 10.0 without gapping: 217
Number of HSP's successfully gapped in prelim test: 208
Number of HSP's that attempted gapping in prelim test: 2010
Number of HSP's gapped (non-prelim): 1669
length of query: 400
length of database: 18,247,518
effective HSP length: 104
effective length of query: 296
effective length of database: 14,309,454
effective search space: 4235598384
effective search space used: 4235598384
T: 11
A: 40
X1: 16 ( 7.4 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 41 (21.8 bits)
S2: 63 (28.9 bits)
Search results were obtained with NCBI BLAST and RefSeq entries.
Home |
Table of Contents |
Search text |
Search genes |
Search sequences |
Purchase |
FAQ |
Blog |
Help
Guide to the Human Genome
Copyright © 2010 by Stewart Scherer. All rights reserved.