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Search of human proteins with 4506003
BLASTP 2.2.11 [Jun-05-2005]
Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer,
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997),
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs", Nucleic Acids Res. 25:3389-3402.
Query= gi|4506003 protein phosphatase 1, catalytic subunit, alpha
isoform 1 [Homo sapiens]
(330 letters)
Database: hs.faa
37,866 sequences; 18,247,518 total letters
Searching..................................................done
Score E
Sequences producing significant alignments: (bits) Value
gi|4506003 protein phosphatase 1, catalytic subunit, alpha isofo... 689 0.0
gi|56790945 protein phosphatase 1, catalytic subunit, alpha isof... 680 0.0
gi|4506007 protein phosphatase 1, catalytic subunit, gamma isofo... 619 e-177
gi|46249376 protein phosphatase 1, catalytic subunit, beta isofo... 605 e-173
gi|4506005 protein phosphatase 1, catalytic subunit, beta isofor... 605 e-173
gi|45827798 protein phosphatase 1, catalytic subunit, alpha isof... 582 e-166
gi|57222565 protein phosphatase 2, catalytic subunit, beta isofo... 300 1e-81
gi|4758952 protein phosphatase 2, catalytic subunit, beta isofor... 300 1e-81
gi|4506017 protein phosphatase 2, catalytic subunit, alpha isofo... 295 5e-80
gi|4506027 protein phosphatase 4, catalytic subunit [Homo sapiens] 293 1e-79
gi|4506029 protein phosphatase 6, catalytic subunit isoform b [H... 267 8e-72
gi|183603929 protein phosphatase 6, catalytic subunit isoform a ... 260 1e-69
gi|183603931 protein phosphatase 6, catalytic subunit isoform c ... 229 3e-60
gi|194688147 protein phosphatase 3, catalytic subunit, alpha iso... 226 3e-59
gi|6715568 protein phosphatase 3, catalytic subunit, alpha isofo... 226 3e-59
gi|194688149 protein phosphatase 3, catalytic subunit, alpha iso... 224 6e-59
gi|21361290 protein phosphatase 3, catalytic subunit, gamma [Hom... 222 4e-58
gi|215272354 protein phosphatase 3, catalytic subunit, beta isof... 221 5e-58
gi|215272352 protein phosphatase 3, catalytic subunit, beta isof... 221 5e-58
gi|11036640 protein phosphatase 3, catalytic subunit, beta isofo... 221 5e-58
gi|5453958 protein phosphatase 5, catalytic subunit [Homo sapiens] 210 2e-54
gi|23312374 protein phosphatase with EF hand calcium-binding dom... 145 6e-35
gi|23312380 protein phosphatase with EF hand calcium-binding dom... 135 5e-32
gi|239752750 PREDICTED: similar to protein phosphatase 2, cataly... 121 7e-28
gi|239747318 PREDICTED: similar to protein phosphatase 2, cataly... 121 7e-28
gi|239741140 PREDICTED: similar to protein phosphatase 2, cataly... 121 7e-28
gi|23312386 serine/threonine protein phosphatase with EF-hand mo... 118 8e-27
gi|23312378 protein phosphatase with EF hand calcium-binding dom... 103 2e-22
gi|190610008 zinc finger protein 317 [Homo sapiens] 30 2.3
>gi|4506003 protein phosphatase 1, catalytic subunit, alpha isoform
1 [Homo sapiens]
Length = 330
Score = 689 bits (1777), Expect = 0.0
Identities = 330/330 (100%), Positives = 330/330 (100%)
Query: 1 MSDSEKLNLDSIIGRLLEVQGSRPGKNVQLTENEIRGLCLKSREIFLSQPILLELEAPLK 60
MSDSEKLNLDSIIGRLLEVQGSRPGKNVQLTENEIRGLCLKSREIFLSQPILLELEAPLK
Sbjct: 1 MSDSEKLNLDSIIGRLLEVQGSRPGKNVQLTENEIRGLCLKSREIFLSQPILLELEAPLK 60
Query: 61 ICGDIHGQYYDLLRLFEYGGFPPESNYLFLGDYVDRGKQSLETICLLLAYKIKYPENFFL 120
ICGDIHGQYYDLLRLFEYGGFPPESNYLFLGDYVDRGKQSLETICLLLAYKIKYPENFFL
Sbjct: 61 ICGDIHGQYYDLLRLFEYGGFPPESNYLFLGDYVDRGKQSLETICLLLAYKIKYPENFFL 120
Query: 121 LRGNHECASINRIYGFYDECKRRYNIKLWKTFTDCFNCLPIAAIVDEKIFCCHGGLSPDL 180
LRGNHECASINRIYGFYDECKRRYNIKLWKTFTDCFNCLPIAAIVDEKIFCCHGGLSPDL
Sbjct: 121 LRGNHECASINRIYGFYDECKRRYNIKLWKTFTDCFNCLPIAAIVDEKIFCCHGGLSPDL 180
Query: 181 QSMEQIRRIMRPTDVPDQGLLCDLLWSDPDKDVQGWGENDRGVSFTFGAEVVAKFLHKHD 240
QSMEQIRRIMRPTDVPDQGLLCDLLWSDPDKDVQGWGENDRGVSFTFGAEVVAKFLHKHD
Sbjct: 181 QSMEQIRRIMRPTDVPDQGLLCDLLWSDPDKDVQGWGENDRGVSFTFGAEVVAKFLHKHD 240
Query: 241 LDLICRAHQVVEDGYEFFAKRQLVTLFSAPNYCGEFDNAGAMMSVDETLMCSFQILKPAD 300
LDLICRAHQVVEDGYEFFAKRQLVTLFSAPNYCGEFDNAGAMMSVDETLMCSFQILKPAD
Sbjct: 241 LDLICRAHQVVEDGYEFFAKRQLVTLFSAPNYCGEFDNAGAMMSVDETLMCSFQILKPAD 300
Query: 301 KNKGKYGQFSGLNPGGRPITPPRNSAKAKK 330
KNKGKYGQFSGLNPGGRPITPPRNSAKAKK
Sbjct: 301 KNKGKYGQFSGLNPGGRPITPPRNSAKAKK 330
>gi|56790945 protein phosphatase 1, catalytic subunit, alpha isoform
3 [Homo sapiens]
Length = 341
Score = 680 bits (1755), Expect = 0.0
Identities = 330/341 (96%), Positives = 330/341 (96%), Gaps = 11/341 (3%)
Query: 1 MSDSEKLNLDSIIGRLLE-----------VQGSRPGKNVQLTENEIRGLCLKSREIFLSQ 49
MSDSEKLNLDSIIGRLLE VQGSRPGKNVQLTENEIRGLCLKSREIFLSQ
Sbjct: 1 MSDSEKLNLDSIIGRLLEGSRVLTPHCAPVQGSRPGKNVQLTENEIRGLCLKSREIFLSQ 60
Query: 50 PILLELEAPLKICGDIHGQYYDLLRLFEYGGFPPESNYLFLGDYVDRGKQSLETICLLLA 109
PILLELEAPLKICGDIHGQYYDLLRLFEYGGFPPESNYLFLGDYVDRGKQSLETICLLLA
Sbjct: 61 PILLELEAPLKICGDIHGQYYDLLRLFEYGGFPPESNYLFLGDYVDRGKQSLETICLLLA 120
Query: 110 YKIKYPENFFLLRGNHECASINRIYGFYDECKRRYNIKLWKTFTDCFNCLPIAAIVDEKI 169
YKIKYPENFFLLRGNHECASINRIYGFYDECKRRYNIKLWKTFTDCFNCLPIAAIVDEKI
Sbjct: 121 YKIKYPENFFLLRGNHECASINRIYGFYDECKRRYNIKLWKTFTDCFNCLPIAAIVDEKI 180
Query: 170 FCCHGGLSPDLQSMEQIRRIMRPTDVPDQGLLCDLLWSDPDKDVQGWGENDRGVSFTFGA 229
FCCHGGLSPDLQSMEQIRRIMRPTDVPDQGLLCDLLWSDPDKDVQGWGENDRGVSFTFGA
Sbjct: 181 FCCHGGLSPDLQSMEQIRRIMRPTDVPDQGLLCDLLWSDPDKDVQGWGENDRGVSFTFGA 240
Query: 230 EVVAKFLHKHDLDLICRAHQVVEDGYEFFAKRQLVTLFSAPNYCGEFDNAGAMMSVDETL 289
EVVAKFLHKHDLDLICRAHQVVEDGYEFFAKRQLVTLFSAPNYCGEFDNAGAMMSVDETL
Sbjct: 241 EVVAKFLHKHDLDLICRAHQVVEDGYEFFAKRQLVTLFSAPNYCGEFDNAGAMMSVDETL 300
Query: 290 MCSFQILKPADKNKGKYGQFSGLNPGGRPITPPRNSAKAKK 330
MCSFQILKPADKNKGKYGQFSGLNPGGRPITPPRNSAKAKK
Sbjct: 301 MCSFQILKPADKNKGKYGQFSGLNPGGRPITPPRNSAKAKK 341
>gi|4506007 protein phosphatase 1, catalytic subunit, gamma isoform
[Homo sapiens]
Length = 323
Score = 619 bits (1595), Expect = e-177
Identities = 301/332 (90%), Positives = 310/332 (93%), Gaps = 11/332 (3%)
Query: 1 MSDSEKLNLDSIIGRLLEVQGSRPGKNVQLTENEIRGLCLKSREIFLSQPILLELEAPLK 60
M+D +KLN+DSII RLLEV+GS+PGKNVQL ENEIRGLCLKSREIFLSQPILLELEAPLK
Sbjct: 1 MADLDKLNIDSIIQRLLEVRGSKPGKNVQLQENEIRGLCLKSREIFLSQPILLELEAPLK 60
Query: 61 ICGDIHGQYYDLLRLFEYGGFPPESNYLFLGDYVDRGKQSLETICLLLAYKIKYPENFFL 120
ICGDIHGQYYDLLRLFEYGGFPPESNYLFLGDYVDRGKQSLETICLLLAYKIKYPENFFL
Sbjct: 61 ICGDIHGQYYDLLRLFEYGGFPPESNYLFLGDYVDRGKQSLETICLLLAYKIKYPENFFL 120
Query: 121 LRGNHECASINRIYGFYDECKRRYNIKLWKTFTDCFNCLPIAAIVDEKIFCCHGGLSPDL 180
LRGNHECASINRIYGFYDECKRRYNIKLWKTFTDCFNCLPIAAIVDEKIFCCHGGLSPDL
Sbjct: 121 LRGNHECASINRIYGFYDECKRRYNIKLWKTFTDCFNCLPIAAIVDEKIFCCHGGLSPDL 180
Query: 181 QSMEQIRRIMRPTDVPDQGLLCDLLWSDPDKDVQGWGENDRGVSFTFGAEVVAKFLHKHD 240
QSMEQIRRIMRPTDVPDQGLLCDLLWSDPDKDV GWGENDRGVSFTFGAEVVAKFLHKHD
Sbjct: 181 QSMEQIRRIMRPTDVPDQGLLCDLLWSDPDKDVLGWGENDRGVSFTFGAEVVAKFLHKHD 240
Query: 241 LDLICRAHQVVEDGYEFFAKRQLVTLFSAPNYCGEFDNAGAMMSVDETLMCSFQILKPAD 300
LDLICRAHQVVEDGYEFFAKRQLVTLFSAPNYCGEFDNAGAMMSVDETLMCSFQILKPA+
Sbjct: 241 LDLICRAHQVVEDGYEFFAKRQLVTLFSAPNYCGEFDNAGAMMSVDETLMCSFQILKPAE 300
Query: 301 KNKGKYGQFSGLNPGGRPITPPRN--SAKAKK 330
K K RP+TPPR + +AKK
Sbjct: 301 KKKPN---------ATRPVTPPRGMITKQAKK 323
>gi|46249376 protein phosphatase 1, catalytic subunit, beta isoform
1 [Homo sapiens]
Length = 327
Score = 605 bits (1559), Expect = e-173
Identities = 293/330 (88%), Positives = 311/330 (94%), Gaps = 4/330 (1%)
Query: 1 MSDSEKLNLDSIIGRLLEVQGSRPGKNVQLTENEIRGLCLKSREIFLSQPILLELEAPLK 60
M+D E LN+DS+I RLLEV+G RPGK VQ+TE E+RGLC+KSREIFLSQPILLELEAPLK
Sbjct: 1 MADGE-LNVDSLITRLLEVRGCRPGKIVQMTEAEVRGLCIKSREIFLSQPILLELEAPLK 59
Query: 61 ICGDIHGQYYDLLRLFEYGGFPPESNYLFLGDYVDRGKQSLETICLLLAYKIKYPENFFL 120
ICGDIHGQY DLLRLFEYGGFPPE+NYLFLGDYVDRGKQSLETICLLLAYKIKYPENFFL
Sbjct: 60 ICGDIHGQYTDLLRLFEYGGFPPEANYLFLGDYVDRGKQSLETICLLLAYKIKYPENFFL 119
Query: 121 LRGNHECASINRIYGFYDECKRRYNIKLWKTFTDCFNCLPIAAIVDEKIFCCHGGLSPDL 180
LRGNHECASINRIYGFYDECKRR+NIKLWKTFTDCFNCLPIAAIVDEKIFCCHGGLSPDL
Sbjct: 120 LRGNHECASINRIYGFYDECKRRFNIKLWKTFTDCFNCLPIAAIVDEKIFCCHGGLSPDL 179
Query: 181 QSMEQIRRIMRPTDVPDQGLLCDLLWSDPDKDVQGWGENDRGVSFTFGAEVVAKFLHKHD 240
QSMEQIRRIMRPTDVPD GLLCDLLWSDPDKDVQGWGENDRGVSFTFGA+VV+KFL++HD
Sbjct: 180 QSMEQIRRIMRPTDVPDTGLLCDLLWSDPDKDVQGWGENDRGVSFTFGADVVSKFLNRHD 239
Query: 241 LDLICRAHQVVEDGYEFFAKRQLVTLFSAPNYCGEFDNAGAMMSVDETLMCSFQILKPAD 300
LDLICRAHQVVEDGYEFFAKRQLVTLFSAPNYCGEFDNAG MMSVDETLMCSFQILKP++
Sbjct: 240 LDLICRAHQVVEDGYEFFAKRQLVTLFSAPNYCGEFDNAGGMMSVDETLMCSFQILKPSE 299
Query: 301 KNKGKYGQFSGLNPGGRPITPPRNSAKAKK 330
K K KY Q+ GLN GRP+TPPR + KK
Sbjct: 300 K-KAKY-QYGGLN-SGRPVTPPRTANPPKK 326
>gi|4506005 protein phosphatase 1, catalytic subunit, beta isoform 1
[Homo sapiens]
Length = 327
Score = 605 bits (1559), Expect = e-173
Identities = 293/330 (88%), Positives = 311/330 (94%), Gaps = 4/330 (1%)
Query: 1 MSDSEKLNLDSIIGRLLEVQGSRPGKNVQLTENEIRGLCLKSREIFLSQPILLELEAPLK 60
M+D E LN+DS+I RLLEV+G RPGK VQ+TE E+RGLC+KSREIFLSQPILLELEAPLK
Sbjct: 1 MADGE-LNVDSLITRLLEVRGCRPGKIVQMTEAEVRGLCIKSREIFLSQPILLELEAPLK 59
Query: 61 ICGDIHGQYYDLLRLFEYGGFPPESNYLFLGDYVDRGKQSLETICLLLAYKIKYPENFFL 120
ICGDIHGQY DLLRLFEYGGFPPE+NYLFLGDYVDRGKQSLETICLLLAYKIKYPENFFL
Sbjct: 60 ICGDIHGQYTDLLRLFEYGGFPPEANYLFLGDYVDRGKQSLETICLLLAYKIKYPENFFL 119
Query: 121 LRGNHECASINRIYGFYDECKRRYNIKLWKTFTDCFNCLPIAAIVDEKIFCCHGGLSPDL 180
LRGNHECASINRIYGFYDECKRR+NIKLWKTFTDCFNCLPIAAIVDEKIFCCHGGLSPDL
Sbjct: 120 LRGNHECASINRIYGFYDECKRRFNIKLWKTFTDCFNCLPIAAIVDEKIFCCHGGLSPDL 179
Query: 181 QSMEQIRRIMRPTDVPDQGLLCDLLWSDPDKDVQGWGENDRGVSFTFGAEVVAKFLHKHD 240
QSMEQIRRIMRPTDVPD GLLCDLLWSDPDKDVQGWGENDRGVSFTFGA+VV+KFL++HD
Sbjct: 180 QSMEQIRRIMRPTDVPDTGLLCDLLWSDPDKDVQGWGENDRGVSFTFGADVVSKFLNRHD 239
Query: 241 LDLICRAHQVVEDGYEFFAKRQLVTLFSAPNYCGEFDNAGAMMSVDETLMCSFQILKPAD 300
LDLICRAHQVVEDGYEFFAKRQLVTLFSAPNYCGEFDNAG MMSVDETLMCSFQILKP++
Sbjct: 240 LDLICRAHQVVEDGYEFFAKRQLVTLFSAPNYCGEFDNAGGMMSVDETLMCSFQILKPSE 299
Query: 301 KNKGKYGQFSGLNPGGRPITPPRNSAKAKK 330
K K KY Q+ GLN GRP+TPPR + KK
Sbjct: 300 K-KAKY-QYGGLN-SGRPVTPPRTANPPKK 326
>gi|45827798 protein phosphatase 1, catalytic subunit, alpha isoform
2 [Homo sapiens]
Length = 286
Score = 582 bits (1500), Expect = e-166
Identities = 286/330 (86%), Positives = 286/330 (86%), Gaps = 44/330 (13%)
Query: 1 MSDSEKLNLDSIIGRLLEVQGSRPGKNVQLTENEIRGLCLKSREIFLSQPILLELEAPLK 60
MSDSEKLNLDSIIGRLLE
Sbjct: 1 MSDSEKLNLDSIIGRLLE------------------------------------------ 18
Query: 61 ICGDIHGQYYDLLRLFEYGGFPPESNYLFLGDYVDRGKQSLETICLLLAYKIKYPENFFL 120
GDIHGQYYDLLRLFEYGGFPPESNYLFLGDYVDRGKQSLETICLLLAYKIKYPENFFL
Sbjct: 19 --GDIHGQYYDLLRLFEYGGFPPESNYLFLGDYVDRGKQSLETICLLLAYKIKYPENFFL 76
Query: 121 LRGNHECASINRIYGFYDECKRRYNIKLWKTFTDCFNCLPIAAIVDEKIFCCHGGLSPDL 180
LRGNHECASINRIYGFYDECKRRYNIKLWKTFTDCFNCLPIAAIVDEKIFCCHGGLSPDL
Sbjct: 77 LRGNHECASINRIYGFYDECKRRYNIKLWKTFTDCFNCLPIAAIVDEKIFCCHGGLSPDL 136
Query: 181 QSMEQIRRIMRPTDVPDQGLLCDLLWSDPDKDVQGWGENDRGVSFTFGAEVVAKFLHKHD 240
QSMEQIRRIMRPTDVPDQGLLCDLLWSDPDKDVQGWGENDRGVSFTFGAEVVAKFLHKHD
Sbjct: 137 QSMEQIRRIMRPTDVPDQGLLCDLLWSDPDKDVQGWGENDRGVSFTFGAEVVAKFLHKHD 196
Query: 241 LDLICRAHQVVEDGYEFFAKRQLVTLFSAPNYCGEFDNAGAMMSVDETLMCSFQILKPAD 300
LDLICRAHQVVEDGYEFFAKRQLVTLFSAPNYCGEFDNAGAMMSVDETLMCSFQILKPAD
Sbjct: 197 LDLICRAHQVVEDGYEFFAKRQLVTLFSAPNYCGEFDNAGAMMSVDETLMCSFQILKPAD 256
Query: 301 KNKGKYGQFSGLNPGGRPITPPRNSAKAKK 330
KNKGKYGQFSGLNPGGRPITPPRNSAKAKK
Sbjct: 257 KNKGKYGQFSGLNPGGRPITPPRNSAKAKK 286
>gi|57222565 protein phosphatase 2, catalytic subunit, beta isoform
[Homo sapiens]
Length = 309
Score = 300 bits (768), Expect = 1e-81
Identities = 138/274 (50%), Positives = 191/274 (69%), Gaps = 2/274 (0%)
Query: 29 QLTENEIRGLCLKSREIFLSQPILLELEAPLKICGDIHGQYYDLLRLFEYGGFPPESNYL 88
QL EN++R LC K++EI + + E+ P+ +CGD+HGQ++DL+ LF GG P++NYL
Sbjct: 22 QLNENQVRTLCEKAKEILTKESNVQEVRCPVTVCGDVHGQFHDLMELFRIGGKSPDTNYL 81
Query: 89 FLGDYVDRGKQSLETICLLLAYKIKYPENFFLLRGNHECASINRIYGFYDECKRRY-NIK 147
F+GDYVDRG S+ET+ LL+A K++YPE +LRGNHE I ++YGFYDEC R+Y N
Sbjct: 82 FMGDYVDRGYYSVETVTLLVALKVRYPERITILRGNHESRQITQVYGFYDECLRKYGNAN 141
Query: 148 LWKTFTDCFNCLPIAAIVDEKIFCCHGGLSPDLQSMEQIRRIMRPTDVPDQGLLCDLLWS 207
+WK FTD F+ LP+ A+VD +IFC HGGLSP + +++ IR + R +VP +G +CDLLWS
Sbjct: 142 VWKYFTDLFDYLPLTALVDGQIFCLHGGLSPSIDTLDHIRALDRLQEVPHEGPMCDLLWS 201
Query: 208 DPDKDVQGWGENDRGVSFTFGAEVVAKFLHKHDLDLICRAHQVVEDGYEFFAKRQLVTLF 267
DPD D GWG + RG +TFG ++ F H + L L+ RAHQ+V +GY + R +VT+F
Sbjct: 202 DPD-DRGGWGISPRGAGYTFGQDISETFNHANGLTLVSRAHQLVMEGYNWCHDRNVVTIF 260
Query: 268 SAPNYCGEFDNAGAMMSVDETLMCSFQILKPADK 301
SAPNYC N A+M +D+TL SF PA +
Sbjct: 261 SAPNYCYRCGNQAAIMELDDTLKYSFLQFDPAPR 294
>gi|4758952 protein phosphatase 2, catalytic subunit, beta isoform
[Homo sapiens]
Length = 309
Score = 300 bits (768), Expect = 1e-81
Identities = 138/274 (50%), Positives = 191/274 (69%), Gaps = 2/274 (0%)
Query: 29 QLTENEIRGLCLKSREIFLSQPILLELEAPLKICGDIHGQYYDLLRLFEYGGFPPESNYL 88
QL EN++R LC K++EI + + E+ P+ +CGD+HGQ++DL+ LF GG P++NYL
Sbjct: 22 QLNENQVRTLCEKAKEILTKESNVQEVRCPVTVCGDVHGQFHDLMELFRIGGKSPDTNYL 81
Query: 89 FLGDYVDRGKQSLETICLLLAYKIKYPENFFLLRGNHECASINRIYGFYDECKRRY-NIK 147
F+GDYVDRG S+ET+ LL+A K++YPE +LRGNHE I ++YGFYDEC R+Y N
Sbjct: 82 FMGDYVDRGYYSVETVTLLVALKVRYPERITILRGNHESRQITQVYGFYDECLRKYGNAN 141
Query: 148 LWKTFTDCFNCLPIAAIVDEKIFCCHGGLSPDLQSMEQIRRIMRPTDVPDQGLLCDLLWS 207
+WK FTD F+ LP+ A+VD +IFC HGGLSP + +++ IR + R +VP +G +CDLLWS
Sbjct: 142 VWKYFTDLFDYLPLTALVDGQIFCLHGGLSPSIDTLDHIRALDRLQEVPHEGPMCDLLWS 201
Query: 208 DPDKDVQGWGENDRGVSFTFGAEVVAKFLHKHDLDLICRAHQVVEDGYEFFAKRQLVTLF 267
DPD D GWG + RG +TFG ++ F H + L L+ RAHQ+V +GY + R +VT+F
Sbjct: 202 DPD-DRGGWGISPRGAGYTFGQDISETFNHANGLTLVSRAHQLVMEGYNWCHDRNVVTIF 260
Query: 268 SAPNYCGEFDNAGAMMSVDETLMCSFQILKPADK 301
SAPNYC N A+M +D+TL SF PA +
Sbjct: 261 SAPNYCYRCGNQAAIMELDDTLKYSFLQFDPAPR 294
>gi|4506017 protein phosphatase 2, catalytic subunit, alpha isoform
[Homo sapiens]
Length = 309
Score = 295 bits (754), Expect = 5e-80
Identities = 135/274 (49%), Positives = 191/274 (69%), Gaps = 2/274 (0%)
Query: 29 QLTENEIRGLCLKSREIFLSQPILLELEAPLKICGDIHGQYYDLLRLFEYGGFPPESNYL 88
QL+E++++ LC K++EI + + E+ P+ +CGD+HGQ++DL+ LF GG P++NYL
Sbjct: 22 QLSESQVKSLCEKAKEILTKESNVQEVRCPVTVCGDVHGQFHDLMELFRIGGKSPDTNYL 81
Query: 89 FLGDYVDRGKQSLETICLLLAYKIKYPENFFLLRGNHECASINRIYGFYDECKRRY-NIK 147
F+GDYVDRG S+ET+ LL+A K++Y E +LRGNHE I ++YGFYDEC R+Y N
Sbjct: 82 FMGDYVDRGYYSVETVTLLVALKVRYRERITILRGNHESRQITQVYGFYDECLRKYGNAN 141
Query: 148 LWKTFTDCFNCLPIAAIVDEKIFCCHGGLSPDLQSMEQIRRIMRPTDVPDQGLLCDLLWS 207
+WK FTD F+ LP+ A+VD +IFC HGGLSP + +++ IR + R +VP +G +CDLLWS
Sbjct: 142 VWKYFTDLFDYLPLTALVDGQIFCLHGGLSPSIDTLDHIRALDRLQEVPHEGPMCDLLWS 201
Query: 208 DPDKDVQGWGENDRGVSFTFGAEVVAKFLHKHDLDLICRAHQVVEDGYEFFAKRQLVTLF 267
DPD D GWG + RG +TFG ++ F H + L L+ RAHQ+V +GY + R +VT+F
Sbjct: 202 DPD-DRGGWGISPRGAGYTFGQDISETFNHANGLTLVSRAHQLVMEGYNWCHDRNVVTIF 260
Query: 268 SAPNYCGEFDNAGAMMSVDETLMCSFQILKPADK 301
SAPNYC N A+M +D+TL SF PA +
Sbjct: 261 SAPNYCYRCGNQAAIMELDDTLKYSFLQFDPAPR 294
>gi|4506027 protein phosphatase 4, catalytic subunit [Homo sapiens]
Length = 307
Score = 293 bits (750), Expect = 1e-79
Identities = 133/271 (49%), Positives = 194/271 (71%), Gaps = 2/271 (0%)
Query: 30 LTENEIRGLCLKSREIFLSQPILLELEAPLKICGDIHGQYYDLLRLFEYGGFPPESNYLF 89
+ E+E++ LC K+REI + + + +++P+ +CGDIHGQ+YDL LF GG PE+NYLF
Sbjct: 20 IKESEVKALCAKAREILVEESNVQRVDSPVTVCGDIHGQFYDLKELFRVGGDVPETNYLF 79
Query: 90 LGDYVDRGKQSLETICLLLAYKIKYPENFFLLRGNHECASINRIYGFYDECKRRY-NIKL 148
+GD+VDRG S+ET LLLA K++YP+ L+RGNHE I ++YGFYDEC R+Y ++ +
Sbjct: 80 MGDFVDRGFYSVETFLLLLALKVRYPDRITLIRGNHESRQITQVYGFYDECLRKYGSVTV 139
Query: 149 WKTFTDCFNCLPIAAIVDEKIFCCHGGLSPDLQSMEQIRRIMRPTDVPDQGLLCDLLWSD 208
W+ T+ F+ L ++AI+D KIFC HGGLSP +Q+++QIR I R +VP G +CDLLWSD
Sbjct: 140 WRYCTEIFDYLSLSAIIDGKIFCVHGGLSPSIQTLDQIRTIDRKQEVPHDGPMCDLLWSD 199
Query: 209 PDKDVQGWGENDRGVSFTFGAEVVAKFLHKHDLDLICRAHQVVEDGYEFFAKRQLVTLFS 268
P+ D GWG + RG + FG++VVA+F +D+D+ICRAHQ+V +GY++ ++T++S
Sbjct: 200 PE-DTTGWGVSPRGAGYLFGSDVVAQFNAANDIDMICRAHQLVMEGYKWHFNETVLTVWS 258
Query: 269 APNYCGEFDNAGAMMSVDETLMCSFQILKPA 299
APNYC N A++ +DE L F I + A
Sbjct: 259 APNYCYRCGNVAAILELDEHLQKDFIIFEAA 289
>gi|4506029 protein phosphatase 6, catalytic subunit isoform b [Homo
sapiens]
Length = 305
Score = 267 bits (683), Expect = 8e-72
Identities = 123/255 (48%), Positives = 176/255 (69%), Gaps = 2/255 (0%)
Query: 30 LTENEIRGLCLKSREIFLSQPILLELEAPLKICGDIHGQYYDLLRLFEYGGFPPESNYLF 89
L EN+++ LC ++ L + + + P+ +CGDIHGQ+YDL LF GG P++NY+F
Sbjct: 19 LPENDLKRLCDYVCDLLLEESNVQPVSTPVTVCGDIHGQFYDLCELFRTGGQVPDTNYIF 78
Query: 90 LGDYVDRGKQSLETICLLLAYKIKYPENFFLLRGNHECASINRIYGFYDECKRRY-NIKL 148
+GD+VDRG SLET LLA K K+P+ LLRGNHE I ++YGFYDEC+ +Y N
Sbjct: 79 MGDFVDRGYYSLETFTYLLALKAKWPDRITLLRGNHESRQITQVYGFYDECQTKYGNANA 138
Query: 149 WKTFTDCFNCLPIAAIVDEKIFCCHGGLSPDLQSMEQIRRIMRPTDVPDQGLLCDLLWSD 208
W+ T F+ L +AA++DE+I C HGGLSPD+++++QIR I R ++P +G CDL+WSD
Sbjct: 139 WRYCTKVFDMLTVAALIDEQILCVHGGLSPDIKTLDQIRTIERNQEIPHKGAFCDLVWSD 198
Query: 209 PDKDVQGWGENDRGVSFTFGAEVVAKFLHKHDLDLICRAHQVVEDGYEFFAKRQLVTLFS 268
P+ DV W + RG + FGA+V +F+H ++L LICRAHQ+V +GY+F +LVT++S
Sbjct: 199 PE-DVDTWAISPRGAGWLFGAKVTNEFVHINNLKLICRAHQLVHEGYKFMFDEKLVTVWS 257
Query: 269 APNYCGEFDNAGAMM 283
APNYC N ++M
Sbjct: 258 APNYCYRCGNIASIM 272
>gi|183603929 protein phosphatase 6, catalytic subunit isoform a
[Homo sapiens]
Length = 342
Score = 260 bits (665), Expect = 1e-69
Identities = 120/247 (48%), Positives = 170/247 (68%), Gaps = 2/247 (0%)
Query: 38 LCLKSREIFLSQPILLELEAPLKICGDIHGQYYDLLRLFEYGGFPPESNYLFLGDYVDRG 97
LC ++ L + + + P+ +CGDIHGQ+YDL LF GG P++NY+F+GD+VDRG
Sbjct: 64 LCDYVCDLLLEESNVQPVSTPVTVCGDIHGQFYDLCELFRTGGQVPDTNYIFMGDFVDRG 123
Query: 98 KQSLETICLLLAYKIKYPENFFLLRGNHECASINRIYGFYDECKRRY-NIKLWKTFTDCF 156
SLET LLA K K+P+ LLRGNHE I ++YGFYDEC+ +Y N W+ T F
Sbjct: 124 YYSLETFTYLLALKAKWPDRITLLRGNHESRQITQVYGFYDECQTKYGNANAWRYCTKVF 183
Query: 157 NCLPIAAIVDEKIFCCHGGLSPDLQSMEQIRRIMRPTDVPDQGLLCDLLWSDPDKDVQGW 216
+ L +AA++DE+I C HGGLSPD+++++QIR I R ++P +G CDL+WSDP+ DV W
Sbjct: 184 DMLTVAALIDEQILCVHGGLSPDIKTLDQIRTIERNQEIPHKGAFCDLVWSDPE-DVDTW 242
Query: 217 GENDRGVSFTFGAEVVAKFLHKHDLDLICRAHQVVEDGYEFFAKRQLVTLFSAPNYCGEF 276
+ RG + FGA+V +F+H ++L LICRAHQ+V +GY+F +LVT++SAPNYC
Sbjct: 243 AISPRGAGWLFGAKVTNEFVHINNLKLICRAHQLVHEGYKFMFDEKLVTVWSAPNYCYRC 302
Query: 277 DNAGAMM 283
N ++M
Sbjct: 303 GNIASIM 309
>gi|183603931 protein phosphatase 6, catalytic subunit isoform c
[Homo sapiens]
Length = 283
Score = 229 bits (583), Expect = 3e-60
Identities = 112/255 (43%), Positives = 160/255 (62%), Gaps = 24/255 (9%)
Query: 30 LTENEIRGLCLKSREIFLSQPILLELEAPLKICGDIHGQYYDLLRLFEYGGFPPESNYLF 89
L EN+++ LC ++ L + + + P+ +CGDIHGQ
Sbjct: 19 LPENDLKRLCDYVCDLLLEESNVQPVSTPVTVCGDIHGQ--------------------- 57
Query: 90 LGDYVDRGKQSLETICLLLAYKIKYPENFFLLRGNHECASINRIYGFYDECKRRY-NIKL 148
GD+VDRG SLET LLA K K+P+ LLRGNHE I ++YGFYDEC+ +Y N
Sbjct: 58 -GDFVDRGYYSLETFTYLLALKAKWPDRITLLRGNHESRQITQVYGFYDECQTKYGNANA 116
Query: 149 WKTFTDCFNCLPIAAIVDEKIFCCHGGLSPDLQSMEQIRRIMRPTDVPDQGLLCDLLWSD 208
W+ T F+ L +AA++DE+I C HGGLSPD+++++QIR I R ++P +G CDL+WSD
Sbjct: 117 WRYCTKVFDMLTVAALIDEQILCVHGGLSPDIKTLDQIRTIERNQEIPHKGAFCDLVWSD 176
Query: 209 PDKDVQGWGENDRGVSFTFGAEVVAKFLHKHDLDLICRAHQVVEDGYEFFAKRQLVTLFS 268
P+ DV W + RG + FGA+V +F+H ++L LICRAHQ+V +GY+F +LVT++S
Sbjct: 177 PE-DVDTWAISPRGAGWLFGAKVTNEFVHINNLKLICRAHQLVHEGYKFMFDEKLVTVWS 235
Query: 269 APNYCGEFDNAGAMM 283
APNYC N ++M
Sbjct: 236 APNYCYRCGNIASIM 250
>gi|194688147 protein phosphatase 3, catalytic subunit, alpha
isoform isoform 2 [Homo sapiens]
Length = 511
Score = 226 bits (575), Expect = 3e-59
Identities = 110/278 (39%), Positives = 171/278 (61%), Gaps = 13/278 (4%)
Query: 26 KNVQLTENEIRGLCLKSREIFLSQPILLELEAPLKICGDIHGQYYDLLRLFEYGGFPPES 85
K +L E+ + + I + LL+++AP+ +CGDIHGQ++DL++LFE GG P +
Sbjct: 52 KEGRLEESVALRIITEGASILRQEKNLLDIDAPVTVCGDIHGQFFDLMKLFEVGGSPANT 111
Query: 86 NYLFLGDYVDRGKQSLETICLLLAYKIKYPENFFLLRGNHECASINRIYGFYDECKRRYN 145
YLFLGDYVDRG S+E + L A KI YP+ FLLRGNHEC + + F ECK +Y+
Sbjct: 112 RYLFLGDYVDRGYFSIECVLYLWALKILYPKTLFLLRGNHECRHLTEYFTFKQECKIKYS 171
Query: 146 IKLWKTFTDCFNCLPIAAIVDEKIFCCHGGLSPDLQSMEQIRRIMRPTDVPDQGLLCDLL 205
+++ D F+CLP+AA+++++ C HGGLSP++ +++ IR++ R + P G +CD+L
Sbjct: 172 ERVYDACMDAFDCLPLAALMNQQFLCVHGGLSPEINTLDDIRKLDRFKEPPAYGPMCDIL 231
Query: 206 WSDP------DKDVQGWGEND-RGVSFTFGAEVVAKFLHKHDLDLICRAHQVVEDGYEFF 258
WSDP +K + + N RG S+ + V +FL ++L I RAH+ + GY +
Sbjct: 232 WSDPLEDFGNEKTQEHFTHNTVRGCSYFYSYPAVCEFLQHNNLLSILRAHEAQDAGYRMY 291
Query: 259 AKRQ------LVTLFSAPNYCGEFDNAGAMMSVDETLM 290
K Q L+T+FSAPNY ++N A++ + +M
Sbjct: 292 RKSQTTGFPSLITIFSAPNYLDVYNNKAAVLKYENNVM 329
>gi|6715568 protein phosphatase 3, catalytic subunit, alpha isoform
isoform 1 [Homo sapiens]
Length = 521
Score = 226 bits (575), Expect = 3e-59
Identities = 110/278 (39%), Positives = 171/278 (61%), Gaps = 13/278 (4%)
Query: 26 KNVQLTENEIRGLCLKSREIFLSQPILLELEAPLKICGDIHGQYYDLLRLFEYGGFPPES 85
K +L E+ + + I + LL+++AP+ +CGDIHGQ++DL++LFE GG P +
Sbjct: 52 KEGRLEESVALRIITEGASILRQEKNLLDIDAPVTVCGDIHGQFFDLMKLFEVGGSPANT 111
Query: 86 NYLFLGDYVDRGKQSLETICLLLAYKIKYPENFFLLRGNHECASINRIYGFYDECKRRYN 145
YLFLGDYVDRG S+E + L A KI YP+ FLLRGNHEC + + F ECK +Y+
Sbjct: 112 RYLFLGDYVDRGYFSIECVLYLWALKILYPKTLFLLRGNHECRHLTEYFTFKQECKIKYS 171
Query: 146 IKLWKTFTDCFNCLPIAAIVDEKIFCCHGGLSPDLQSMEQIRRIMRPTDVPDQGLLCDLL 205
+++ D F+CLP+AA+++++ C HGGLSP++ +++ IR++ R + P G +CD+L
Sbjct: 172 ERVYDACMDAFDCLPLAALMNQQFLCVHGGLSPEINTLDDIRKLDRFKEPPAYGPMCDIL 231
Query: 206 WSDP------DKDVQGWGEND-RGVSFTFGAEVVAKFLHKHDLDLICRAHQVVEDGYEFF 258
WSDP +K + + N RG S+ + V +FL ++L I RAH+ + GY +
Sbjct: 232 WSDPLEDFGNEKTQEHFTHNTVRGCSYFYSYPAVCEFLQHNNLLSILRAHEAQDAGYRMY 291
Query: 259 AKRQ------LVTLFSAPNYCGEFDNAGAMMSVDETLM 290
K Q L+T+FSAPNY ++N A++ + +M
Sbjct: 292 RKSQTTGFPSLITIFSAPNYLDVYNNKAAVLKYENNVM 329
>gi|194688149 protein phosphatase 3, catalytic subunit, alpha
isoform isoform 3 [Homo sapiens]
Length = 469
Score = 224 bits (572), Expect = 6e-59
Identities = 112/280 (40%), Positives = 171/280 (61%), Gaps = 13/280 (4%)
Query: 26 KNVQLTENEIRGLCLKSREIFLSQPILLELEAPLKICGDIHGQYYDLLRLFEYGGFPPES 85
K +L E+ + + I + LL+++AP+ +CGDIHGQ++DL++LFE GG P +
Sbjct: 52 KEGRLEESVALRIITEGASILRQEKNLLDIDAPVTVCGDIHGQFFDLMKLFEVGGSPANT 111
Query: 86 NYLFLGDYVDRGKQSLETICLLLAYKIKYPENFFLLRGNHECASINRIYGFYDECKRRYN 145
YLFLGDYVDRG S+E + L A KI YP+ FLLRGNHEC + + F ECK +Y+
Sbjct: 112 RYLFLGDYVDRGYFSIECVLYLWALKILYPKTLFLLRGNHECRHLTEYFTFKQECKIKYS 171
Query: 146 IKLWKTFTDCFNCLPIAAIVDEKIFCCHGGLSPDLQSMEQIRRIMRPTDVPDQGLLCDLL 205
+++ D F+CLP+AA+++++ C HGGLSP++ +++ IR++ R + P G +CD+L
Sbjct: 172 ERVYDACMDAFDCLPLAALMNQQFLCVHGGLSPEINTLDDIRKLDRFKEPPAYGPMCDIL 231
Query: 206 WSDP------DKDVQGWGEND-RGVSFTFGAEVVAKFLHKHDLDLICRAHQVVEDGYEFF 258
WSDP +K + + N RG S+ + V +FL ++L I RAH+ + GY +
Sbjct: 232 WSDPLEDFGNEKTQEHFTHNTVRGCSYFYSYPAVCEFLQHNNLLSILRAHEAQDAGYRMY 291
Query: 259 AKRQ------LVTLFSAPNYCGEFDNAGAMMSVDETLMCS 292
K Q L+T+FSAPNY ++N M V+ +CS
Sbjct: 292 RKSQTTGFPSLITIFSAPNYLDVYNNKVTEMLVNVLNICS 331
>gi|21361290 protein phosphatase 3, catalytic subunit, gamma [Homo
sapiens]
Length = 512
Score = 222 bits (565), Expect = 4e-58
Identities = 104/259 (40%), Positives = 166/259 (64%), Gaps = 13/259 (5%)
Query: 45 IFLSQPILLELEAPLKICGDIHGQYYDLLRLFEYGGFPPESNYLFLGDYVDRGKQSLETI 104
I + ++E++AP+ +CGDIHGQ++DL++LFE GG P + YLFLGDYVDRG S+E +
Sbjct: 67 ILRQEKTMIEVDAPITVCGDIHGQFFDLMKLFEVGGSPSNTRYLFLGDYVDRGYFSIECV 126
Query: 105 CLLLAYKIKYPENFFLLRGNHECASINRIYGFYDECKRRYNIKLWKTFTDCFNCLPIAAI 164
L + KI +P+ FLLRGNHEC + + F EC+ +Y+ +++ + F+CLP+AA+
Sbjct: 127 LYLWSLKINHPKTLFLLRGNHECRHLTDYFTFKQECRIKYSEQVYDACMETFDCLPLAAL 186
Query: 165 VDEKIFCCHGGLSPDLQSMEQIRRIMRPTDVPDQGLLCDLLWSDPDKD------VQGWGE 218
++++ C HGG+SP++ S++ IR++ R T+ P G +CDLLWSDP +D ++ +
Sbjct: 187 LNQQFLCVHGGMSPEITSLDDIRKLDRFTEPPAFGPVCDLLWSDPSEDYGNEKTLEHYTH 246
Query: 219 ND-RGVSFTFGAEVVAKFLHKHDLDLICRAHQVVEDGYEFFAKRQ------LVTLFSAPN 271
N RG S+ + V +FL ++L I RAH+ + GY + K Q L+T+FSAPN
Sbjct: 247 NTVRGCSYFYSYPAVCEFLQNNNLLSIIRAHEAQDAGYRMYRKSQATGFPSLITIFSAPN 306
Query: 272 YCGEFDNAGAMMSVDETLM 290
Y ++N A++ + +M
Sbjct: 307 YLDVYNNKAAVLKYENNVM 325
>gi|215272354 protein phosphatase 3, catalytic subunit, beta isoform
c [Homo sapiens]
Length = 515
Score = 221 bits (564), Expect = 5e-58
Identities = 105/259 (40%), Positives = 160/259 (61%), Gaps = 13/259 (5%)
Query: 45 IFLSQPILLELEAPLKICGDIHGQYYDLLRLFEYGGFPPESNYLFLGDYVDRGKQSLETI 104
I + ++E+EAP+ +CGDIHGQ++DL++LFE GG P + YLFLGDYVDRG S+E +
Sbjct: 80 ILRREKTMIEVEAPITVCGDIHGQFFDLMKLFEVGGSPANTRYLFLGDYVDRGYFSIECV 139
Query: 105 CLLLAYKIKYPENFFLLRGNHECASINRIYGFYDECKRRYNIKLWKTFTDCFNCLPIAAI 164
L KI YP FLLRGNHEC + + F ECK +Y+ ++++ + F+ LP+AA+
Sbjct: 140 LYLWVLKILYPSTLFLLRGNHECRHLTEYFTFKQECKIKYSERVYEACMEAFDSLPLAAL 199
Query: 165 VDEKIFCCHGGLSPDLQSMEQIRRIMRPTDVPDQGLLCDLLWSDPDKDVQGWGEND---- 220
++++ C HGGLSP++ +++ IRR+ R + P G +CDLLWSDP +D +
Sbjct: 200 LNQQFLCVHGGLSPEIHTLDDIRRLDRFKEPPAFGPMCDLLWSDPSEDFGNEKSQEHFSH 259
Query: 221 ---RGVSFTFGAEVVAKFLHKHDLDLICRAHQVVEDGYEFFAKRQ------LVTLFSAPN 271
RG S+ + V +FL ++L I RAH+ + GY + K Q L+T+FSAPN
Sbjct: 260 NTVRGCSYFYNYPAVCEFLQNNNLLSIIRAHEAQDAGYRMYRKSQTTGFPSLITIFSAPN 319
Query: 272 YCGEFDNAGAMMSVDETLM 290
Y ++N A++ + +M
Sbjct: 320 YLDVYNNKAAVLKYENNVM 338
>gi|215272352 protein phosphatase 3, catalytic subunit, beta isoform
a [Homo sapiens]
Length = 525
Score = 221 bits (564), Expect = 5e-58
Identities = 105/259 (40%), Positives = 160/259 (61%), Gaps = 13/259 (5%)
Query: 45 IFLSQPILLELEAPLKICGDIHGQYYDLLRLFEYGGFPPESNYLFLGDYVDRGKQSLETI 104
I + ++E+EAP+ +CGDIHGQ++DL++LFE GG P + YLFLGDYVDRG S+E +
Sbjct: 80 ILRREKTMIEVEAPITVCGDIHGQFFDLMKLFEVGGSPANTRYLFLGDYVDRGYFSIECV 139
Query: 105 CLLLAYKIKYPENFFLLRGNHECASINRIYGFYDECKRRYNIKLWKTFTDCFNCLPIAAI 164
L KI YP FLLRGNHEC + + F ECK +Y+ ++++ + F+ LP+AA+
Sbjct: 140 LYLWVLKILYPSTLFLLRGNHECRHLTEYFTFKQECKIKYSERVYEACMEAFDSLPLAAL 199
Query: 165 VDEKIFCCHGGLSPDLQSMEQIRRIMRPTDVPDQGLLCDLLWSDPDKDVQGWGEND---- 220
++++ C HGGLSP++ +++ IRR+ R + P G +CDLLWSDP +D +
Sbjct: 200 LNQQFLCVHGGLSPEIHTLDDIRRLDRFKEPPAFGPMCDLLWSDPSEDFGNEKSQEHFSH 259
Query: 221 ---RGVSFTFGAEVVAKFLHKHDLDLICRAHQVVEDGYEFFAKRQ------LVTLFSAPN 271
RG S+ + V +FL ++L I RAH+ + GY + K Q L+T+FSAPN
Sbjct: 260 NTVRGCSYFYNYPAVCEFLQNNNLLSIIRAHEAQDAGYRMYRKSQTTGFPSLITIFSAPN 319
Query: 272 YCGEFDNAGAMMSVDETLM 290
Y ++N A++ + +M
Sbjct: 320 YLDVYNNKAAVLKYENNVM 338
>gi|11036640 protein phosphatase 3, catalytic subunit, beta isoform
b [Homo sapiens]
Length = 524
Score = 221 bits (564), Expect = 5e-58
Identities = 105/259 (40%), Positives = 160/259 (61%), Gaps = 13/259 (5%)
Query: 45 IFLSQPILLELEAPLKICGDIHGQYYDLLRLFEYGGFPPESNYLFLGDYVDRGKQSLETI 104
I + ++E+EAP+ +CGDIHGQ++DL++LFE GG P + YLFLGDYVDRG S+E +
Sbjct: 80 ILRREKTMIEVEAPITVCGDIHGQFFDLMKLFEVGGSPANTRYLFLGDYVDRGYFSIECV 139
Query: 105 CLLLAYKIKYPENFFLLRGNHECASINRIYGFYDECKRRYNIKLWKTFTDCFNCLPIAAI 164
L KI YP FLLRGNHEC + + F ECK +Y+ ++++ + F+ LP+AA+
Sbjct: 140 LYLWVLKILYPSTLFLLRGNHECRHLTEYFTFKQECKIKYSERVYEACMEAFDSLPLAAL 199
Query: 165 VDEKIFCCHGGLSPDLQSMEQIRRIMRPTDVPDQGLLCDLLWSDPDKDVQGWGEND---- 220
++++ C HGGLSP++ +++ IRR+ R + P G +CDLLWSDP +D +
Sbjct: 200 LNQQFLCVHGGLSPEIHTLDDIRRLDRFKEPPAFGPMCDLLWSDPSEDFGNEKSQEHFSH 259
Query: 221 ---RGVSFTFGAEVVAKFLHKHDLDLICRAHQVVEDGYEFFAKRQ------LVTLFSAPN 271
RG S+ + V +FL ++L I RAH+ + GY + K Q L+T+FSAPN
Sbjct: 260 NTVRGCSYFYNYPAVCEFLQNNNLLSIIRAHEAQDAGYRMYRKSQTTGFPSLITIFSAPN 319
Query: 272 YCGEFDNAGAMMSVDETLM 290
Y ++N A++ + +M
Sbjct: 320 YLDVYNNKAAVLKYENNVM 338
>gi|5453958 protein phosphatase 5, catalytic subunit [Homo sapiens]
Length = 499
Score = 210 bits (534), Expect = 2e-54
Identities = 103/222 (46%), Positives = 145/222 (65%), Gaps = 3/222 (1%)
Query: 59 LKICGDIHGQYYDLLRLFEYGGFPPESN-YLFLGDYVDRGKQSLETICLLLAYKIKYPEN 117
+ +CGD HGQ+YDLL +FE G P E+N Y+F GD+VDRG S+E I L +K+ YP++
Sbjct: 237 ITVCGDTHGQFYDLLNIFELNGLPSETNPYIFNGDFVDRGSFSVEVILTLFGFKLLYPDH 296
Query: 118 FFLLRGNHECASINRIYGFYDECKRRYNIKLWKTFTDCFNCLPIAAIVDEKIFCCHGGL- 176
F LLRGNHE ++N+IYGF E K +Y ++++ F++ F LP+A ++ K+ HGGL
Sbjct: 297 FHLLRGNHETDNMNQIYGFEGEVKAKYTAQMYELFSEVFEWLPLAQCINGKVLIMHGGLF 356
Query: 177 SPDLQSMEQIRRIMRPTDVPDQGLLCDLLWSDPDKDVQGWGENDRGVSFTFGAEVVAKFL 236
S D +++ IR+I R PD G +CDLLWSDP G + RGVS FG +V FL
Sbjct: 357 SEDGVTLDDIRKIERNRQPPDSGPMCDLLWSDPQPQ-NGRSISKRGVSCQFGPDVTKAFL 415
Query: 237 HKHDLDLICRAHQVVEDGYEFFAKRQLVTLFSAPNYCGEFDN 278
+++LD I R+H+V +GYE + VT+FSAPNYC + N
Sbjct: 416 EENNLDYIIRSHEVKAEGYEVAHGGRCVTVFSAPNYCDQMGN 457
>gi|23312374 protein phosphatase with EF hand calcium-binding domain
1 isoform 1b [Homo sapiens]
Length = 625
Score = 145 bits (365), Expect = 6e-35
Identities = 86/244 (35%), Positives = 129/244 (52%), Gaps = 19/244 (7%)
Query: 61 ICGDIHGQYYDLLRLFEYGGFPPESN-YLFLGDYVDRGKQSLETICLLLAYKIKYPENFF 119
ICGD+HG+ DL +F G P E N Y+F GD+VDRGK S+E + +L + YP +
Sbjct: 169 ICGDLHGKLDDLFLIFYKNGLPSERNPYVFNGDFVDRGKNSIEILMILCVSFLVYPNDLH 228
Query: 120 LLRGNHECASINRIYGFYDECKRRYNI---KLWKTFTDCFNCLPIAAIVDEKIFCCHGGL 176
L RGNHE +N YGF E +Y + ++ + + + LPI IVD +I HGG+
Sbjct: 229 LNRGNHEDFMMNLRYGFTKEILHKYKLHGKRILQILEEFYAWLPIGTIVDNEILVIHGGI 288
Query: 177 S--PDLQSMEQIRR------IMRPTDV-------PDQGLLCDLLWSDPDKDVQGWGENDR 221
S DL + ++ R ++ PT+ + D+LWSDP + R
Sbjct: 289 SETTDLNLLHRVERNKMKSVLIPPTETNRDHDTDSKHNKIIDILWSDPRGKNGCFPNTCR 348
Query: 222 GVSFTFGAEVVAKFLHKHDLDLICRAHQVVEDGYEFFAKRQLVTLFSAPNYCGEFDNAGA 281
G FG +V +K L+K+ L ++ R+H+ +GYE ++VT+FSA NY E N GA
Sbjct: 349 GGGCYFGPDVTSKILNKYQLKMLIRSHECKPEGYEICHDGKVVTIFSASNYYEEGSNRGA 408
Query: 282 MMSV 285
+ +
Sbjct: 409 YIKL 412
>gi|23312380 protein phosphatase with EF hand calcium-binding domain
1 isoform 1 [Homo sapiens]
Length = 653
Score = 135 bits (340), Expect = 5e-32
Identities = 88/272 (32%), Positives = 132/272 (48%), Gaps = 47/272 (17%)
Query: 61 ICGDIHGQYYDLLRLFEYGGFPPESN-YLFLGDYVDRGKQSLETICLLLAYKIKYPENFF 119
ICGD+HG+ DL +F G P E N Y+F GD+VDRGK S+E + +L + YP +
Sbjct: 169 ICGDLHGKLDDLFLIFYKNGLPSERNPYVFNGDFVDRGKNSIEILMILCVSFLVYPNDLH 228
Query: 120 LLRGNHECASINRIYGFYDECKRRYNI---KLWKTFTDCFNCLPIAAIVDEKIFCCHGGL 176
L RGNHE +N YGF E +Y + ++ + + + LPI IVD +I HGG+
Sbjct: 229 LNRGNHEDFMMNLRYGFTKEILHKYKLHGKRILQILEEFYAWLPIGTIVDNEILVIHGGI 288
Query: 177 S--PDLQSMEQIRR------IMRPTDV----------------------------PDQGL 200
S DL + ++ R ++ PT+ P + L
Sbjct: 289 SETTDLNLLHRVERNKMKSVLIPPTETNRDHDTDSKHNKVGVTFNAHGRIKTNGSPTEHL 348
Query: 201 -------LCDLLWSDPDKDVQGWGENDRGVSFTFGAEVVAKFLHKHDLDLICRAHQVVED 253
+ D+LWSDP + RG FG +V +K L+K+ L ++ R+H+ +
Sbjct: 349 TEHEWEQIIDILWSDPRGKNGCFPNTCRGGGCYFGPDVTSKILNKYQLKMLIRSHECKPE 408
Query: 254 GYEFFAKRQLVTLFSAPNYCGEFDNAGAMMSV 285
GYE ++VT+FSA NY E N GA + +
Sbjct: 409 GYEICHDGKVVTIFSASNYYEEGSNRGAYIKL 440
>gi|239752750 PREDICTED: similar to protein phosphatase 2, catalytic
subunit, alpha [Homo sapiens]
Length = 384
Score = 121 bits (304), Expect = 7e-28
Identities = 77/244 (31%), Positives = 113/244 (46%), Gaps = 55/244 (22%)
Query: 30 LTENEIRGLCLKSREIFLSQPILLELEAPLKICGDIHGQYYDLLRLFEYGGFPPESNYLF 89
L +++ LC +++EI + E+ P+ + GD HGQ
Sbjct: 172 LGSRKVKSLCKEAKEILTEESNAQEVWCPVTVSGDKHGQ--------------------- 210
Query: 90 LGDYVDRGKQSLETICLLLAYKIKYPENFFLLRGNHECASINRIYGFYDECKRRYNIKLW 149
GDY+DRG S+E + LLLA K+ Y E +L NHE I ++Y Y+EC R++
Sbjct: 211 -GDYIDRGYYSIEIVMLLLAVKVSYHECVTILPRNHESRQITQVYHSYEECLRKHG---- 265
Query: 150 KTFTDCFNCLPIAAIVDEKIFCCHGGLSPDLQSMEQIRRIMRPTDVPDQGLLCDLLWSDP 209
A D ++FC HGGLSP + ++ IR + +P +G + DLL+SDP
Sbjct: 266 ------------NANGDGQLFCLHGGLSPSVDTLHHIRTLNCLQKIPHEGPMGDLLYSDP 313
Query: 210 DKDVQGWGENDRGVSFTFGAEVVAKFLHKHDLDLICRAHQVVEDGYEFFAKRQLVTLFSA 269
D D TF H L L+ RAHQ+V G+ + +V +FS
Sbjct: 314 D---------DHDTPETFN--------HASGLRLVSRAHQLVMVGHNWCHDWNVVAIFST 356
Query: 270 PNYC 273
PNYC
Sbjct: 357 PNYC 360
>gi|239747318 PREDICTED: similar to protein phosphatase 2, catalytic
subunit, alpha [Homo sapiens]
Length = 254
Score = 121 bits (304), Expect = 7e-28
Identities = 77/244 (31%), Positives = 113/244 (46%), Gaps = 55/244 (22%)
Query: 30 LTENEIRGLCLKSREIFLSQPILLELEAPLKICGDIHGQYYDLLRLFEYGGFPPESNYLF 89
L +++ LC +++EI + E+ P+ + GD HGQ
Sbjct: 51 LGSRKVKSLCKEAKEILTEESNAQEVWCPVTVSGDKHGQ--------------------- 89
Query: 90 LGDYVDRGKQSLETICLLLAYKIKYPENFFLLRGNHECASINRIYGFYDECKRRYNIKLW 149
GDY+DRG S+E + LLLA K+ Y E +L NHE I ++Y Y+EC R++
Sbjct: 90 -GDYIDRGYYSIEIVMLLLAVKVSYHECVTILPRNHESRQITQVYHSYEECLRKHG---- 144
Query: 150 KTFTDCFNCLPIAAIVDEKIFCCHGGLSPDLQSMEQIRRIMRPTDVPDQGLLCDLLWSDP 209
A D ++FC HGGLSP + ++ IR + +P +G + DLL+SDP
Sbjct: 145 ------------NANGDGQLFCLHGGLSPSVDTLHHIRTLNCLQKIPHEGPMGDLLYSDP 192
Query: 210 DKDVQGWGENDRGVSFTFGAEVVAKFLHKHDLDLICRAHQVVEDGYEFFAKRQLVTLFSA 269
D D TF H L L+ RAHQ+V G+ + +V +FS
Sbjct: 193 D---------DHDTPETFN--------HASGLRLVSRAHQLVMVGHNWCHDWNVVAIFST 235
Query: 270 PNYC 273
PNYC
Sbjct: 236 PNYC 239
>gi|239741140 PREDICTED: similar to protein phosphatase 2, catalytic
subunit, alpha [Homo sapiens]
Length = 254
Score = 121 bits (304), Expect = 7e-28
Identities = 77/244 (31%), Positives = 113/244 (46%), Gaps = 55/244 (22%)
Query: 30 LTENEIRGLCLKSREIFLSQPILLELEAPLKICGDIHGQYYDLLRLFEYGGFPPESNYLF 89
L +++ LC +++EI + E+ P+ + GD HGQ
Sbjct: 51 LGSRKVKSLCKEAKEILTEESNAQEVWCPVTVSGDKHGQ--------------------- 89
Query: 90 LGDYVDRGKQSLETICLLLAYKIKYPENFFLLRGNHECASINRIYGFYDECKRRYNIKLW 149
GDY+DRG S+E + LLLA K+ Y E +L NHE I ++Y Y+EC R++
Sbjct: 90 -GDYIDRGYYSIEIVMLLLAVKVSYHECVTILPRNHESRQITQVYHSYEECLRKHG---- 144
Query: 150 KTFTDCFNCLPIAAIVDEKIFCCHGGLSPDLQSMEQIRRIMRPTDVPDQGLLCDLLWSDP 209
A D ++FC HGGLSP + ++ IR + +P +G + DLL+SDP
Sbjct: 145 ------------NANGDGQLFCLHGGLSPSVDTLHHIRTLNCLQKIPHEGPMGDLLYSDP 192
Query: 210 DKDVQGWGENDRGVSFTFGAEVVAKFLHKHDLDLICRAHQVVEDGYEFFAKRQLVTLFSA 269
D D TF H L L+ RAHQ+V G+ + +V +FS
Sbjct: 193 D---------DHDTPETFN--------HASGLRLVSRAHQLVMVGHNWCHDWNVVAIFST 235
Query: 270 PNYC 273
PNYC
Sbjct: 236 PNYC 239
>gi|23312386 serine/threonine protein phosphatase with EF-hand
motifs 2 [Homo sapiens]
Length = 753
Score = 118 bits (295), Expect = 8e-27
Identities = 58/136 (42%), Positives = 87/136 (63%), Gaps = 6/136 (4%)
Query: 59 LKICGDIHGQYYDLLRLFEYGGFP-PESNYLFLGDYVDRGKQSLETICLLLAYKIKYPEN 117
+ +CGD+HGQ DL+ +F G P PE +Y+F GD+VDRGK S+E + +L A+ + YP+
Sbjct: 174 ITVCGDLHGQLDDLIFIFYKNGLPSPERSYVFNGDFVDRGKDSVEILMILFAFMLVYPKE 233
Query: 118 FFLLRGNHECASINRIYGFYDECKRRYNI---KLWKTFTDCFNCLPIAAIVDEKIFCCHG 174
F L RGNHE +N YGF E +Y + ++ +T D F LP+A ++DEK+ HG
Sbjct: 234 FHLNRGNHEDHMVNLRYGFTKEVMNKYKVHGKEILRTLQDVFCWLPLATLIDEKVLILHG 293
Query: 175 GLS--PDLQSMEQIRR 188
G+S DL+ +++I R
Sbjct: 294 GVSDITDLELLDKIER 309
Score = 59.7 bits (143), Expect = 3e-09
Identities = 30/87 (34%), Positives = 46/87 (52%)
Query: 203 DLLWSDPDKDVQGWGENDRGVSFTFGAEVVAKFLHKHDLDLICRAHQVVEDGYEFFAKRQ 262
D+LWSDP RG FG +V + L K+++ + R+H+ +GYEF R+
Sbjct: 443 DILWSDPMAQEGCKANTIRGGGCYFGPDVTQQLLQKYNMQFLIRSHECKPEGYEFCHNRK 502
Query: 263 LVTLFSAPNYCGEFDNAGAMMSVDETL 289
++T+FSA NY N GA + + L
Sbjct: 503 VLTIFSASNYYEVGSNRGAYVKLGPAL 529
>gi|23312378 protein phosphatase with EF hand calcium-binding domain
1 isoform 3 [Homo sapiens]
Length = 591
Score = 103 bits (257), Expect = 2e-22
Identities = 76/237 (32%), Positives = 111/237 (46%), Gaps = 39/237 (16%)
Query: 61 ICGDIHGQYYDLLRLFEYGGFPPESN-YLFLGDYVDRGKQSLETICLLLAYKIKYPENFF 119
ICGD+HG+ DL +F G P E N Y+F GD+VDRGK S+E + +L + YP +
Sbjct: 169 ICGDLHGKLDDLFLIFYKNGLPSERNPYVFNGDFVDRGKNSIEILMILCVSFLVYPNDLH 228
Query: 120 LLRGNHECASINRIYGFYDECKRRYNI---KLWKTFTDCFNCLPIAAIVDEKIFCCHGGL 176
L RGNHE +N YGF E +Y + ++ + + + LPI IVD +I HGG+
Sbjct: 229 LNRGNHEDFMMNLRYGFTKEILHKYKLHGKRILQILEEFYAWLPIGTIVDNEILVIHGGI 288
Query: 177 S--PDLQSMEQIRR------IMRPTDVPDQGLLCDLLWSDPDKDVQGWGENDRGVSFTFG 228
S DL + ++ R ++ PT+ D D D + N GV+F
Sbjct: 289 SETTDLNLLHRVERNKMKSVLIPPTETN----------RDHDTDSK---HNKVGVTFNAH 335
Query: 229 AEVVAKFLHKHDLDLICRAHQVVEDGYEFFAKRQLVTLFSAPNYCGEFDNAGAMMSV 285
+ + E +E Q+VT+FSA NY E N GA + +
Sbjct: 336 GRIKTNG---------SPTEHLTEHEWE-----QVVTIFSASNYYEEGSNRGAYIKL 378
>gi|190610008 zinc finger protein 317 [Homo sapiens]
Length = 595
Score = 30.4 bits (67), Expect = 2.3
Identities = 22/96 (22%), Positives = 42/96 (43%), Gaps = 12/96 (12%)
Query: 125 HECASINRIYGFYDECKRRYNIKLWKTFTDCFNC-----------LPIAAIVDEKIF-CC 172
+ECA+ +++G Y +R ++ L K +C C + + EK + C
Sbjct: 474 YECAACGKVFGDYLSRRRHMSVHLVKKRVECRQCGKAFRNQSTLKTHMRSHTGEKPYECD 533
Query: 173 HGGLSPDLQSMEQIRRIMRPTDVPDQGLLCDLLWSD 208
H G + + S + R + + P + L+C +SD
Sbjct: 534 HCGKAFSIGSNLNVHRRIHTGEKPYECLVCGKAFSD 569
Database: hs.faa
Posted date: Aug 4, 2009 4:42 PM
Number of letters in database: 18,247,518
Number of sequences in database: 37,866
Lambda K H
0.323 0.142 0.446
Gapped
Lambda K H
0.267 0.0410 0.140
Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Hits to DB: 13,927,127
Number of Sequences: 37866
Number of extensions: 639135
Number of successful extensions: 1061
Number of sequences better than 10.0: 29
Number of HSP's better than 10.0 without gapping: 28
Number of HSP's successfully gapped in prelim test: 1
Number of HSP's that attempted gapping in prelim test: 974
Number of HSP's gapped (non-prelim): 33
length of query: 330
length of database: 18,247,518
effective HSP length: 103
effective length of query: 227
effective length of database: 14,347,320
effective search space: 3256841640
effective search space used: 3256841640
T: 11
A: 40
X1: 16 ( 7.5 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 41 (21.9 bits)
S2: 62 (28.5 bits)
Search results were obtained with NCBI BLAST and RefSeq entries.
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Guide to the Human Genome
Copyright © 2010 by Stewart Scherer. All rights reserved.