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Search of human proteins with 4505401
BLASTP 2.2.11 [Jun-05-2005]
Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer,
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997),
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs", Nucleic Acids Res. 25:3389-3402.
Query= gi|4505401 NK2 transcription factor related, locus 2 [Homo
sapiens]
(273 letters)
Database: hs.faa
37,866 sequences; 18,247,518 total letters
Searching..................................................done
Score E
Sequences producing significant alignments: (bits) Value
gi|4505401 NK2 transcription factor related, locus 2 [Homo sapiens] 558 e-159
gi|31377777 NK2 homeobox 8 [Homo sapiens] 151 7e-37
gi|157426823 NK2 homeobox 4 [Homo sapiens] 142 3e-34
gi|148746211 NK2 transcription factor related, locus 3 [Homo sap... 142 4e-34
gi|210147470 NK2 transcription factor related, locus 6 [Homo sap... 139 2e-33
gi|118766339 thyroid transcription factor 1 isoform 1 [Homo sapi... 137 1e-32
gi|4507715 thyroid transcription factor 1 isoform 2 [Homo sapiens] 137 1e-32
gi|4758090 NK2 transcription factor related, locus 5 [Homo sapiens] 134 1e-31
gi|4502365 NK3 homeobox 2 [Homo sapiens] 97 1e-20
gi|116805350 homeo box (H6 family) 1 [Homo sapiens] 87 1e-17
gi|157743259 H6 family homeobox 3 [Homo sapiens] 80 2e-15
gi|70608170 H6 family homeobox 2 [Homo sapiens] 78 7e-15
gi|19923352 NK3 homeobox 1 [Homo sapiens] 78 7e-15
gi|24497515 homeobox A3 isoform b [Homo sapiens] 75 8e-14
gi|24497513 homeobox A3 isoform a [Homo sapiens] 75 8e-14
gi|13562112 homeobox A3 isoform a [Homo sapiens] 75 8e-14
gi|45593144 gastrulation brain homeo box 2 [Homo sapiens] 74 1e-13
gi|64225290 distal-less homeobox 1 isoform 1 [Homo sapiens] 74 2e-13
gi|4885185 distal-less homeobox 3 [Homo sapiens] 72 4e-13
gi|4885187 distal-less homeobox 5 [Homo sapiens] 72 4e-13
gi|239742243 PREDICTED: HPX-153 homeobox [Homo sapiens] 72 5e-13
gi|7706621 T-cell leukemia homeobox 2 [Homo sapiens] 72 7e-13
gi|4758168 distal-less homeobox 2 [Homo sapiens] 71 9e-13
gi|239753784 PREDICTED: NK1 homeobox 1 [Homo sapiens] 71 9e-13
gi|23097236 homeobox A9 [Homo sapiens] 70 2e-12
gi|82659115 distal-less homeobox 6 [Homo sapiens] 69 3e-12
gi|121114296 caudal type homeobox 1 [Homo sapiens] 69 3e-12
gi|19923391 homeobox D3 [Homo sapiens] 69 4e-12
gi|20143962 distal-less homeobox 4 isoform a [Homo sapiens] 69 4e-12
gi|149588930 gastrulation brain homeo box 1 [Homo sapiens] 69 4e-12
>gi|4505401 NK2 transcription factor related, locus 2 [Homo sapiens]
Length = 273
Score = 558 bits (1437), Expect = e-159
Identities = 273/273 (100%), Positives = 273/273 (100%)
Query: 1 MSLTNTKTGFSVKDILDLPDTNDEEGSVAEGPEEENEGPEPAKRAGPLGQGALDAVQSLP 60
MSLTNTKTGFSVKDILDLPDTNDEEGSVAEGPEEENEGPEPAKRAGPLGQGALDAVQSLP
Sbjct: 1 MSLTNTKTGFSVKDILDLPDTNDEEGSVAEGPEEENEGPEPAKRAGPLGQGALDAVQSLP 60
Query: 61 LKNPFYDSSDNPYTRWLASTEGLQYSLHGLAAGAPPQDSSSKSPEPSADESPDNDKETPG 120
LKNPFYDSSDNPYTRWLASTEGLQYSLHGLAAGAPPQDSSSKSPEPSADESPDNDKETPG
Sbjct: 61 LKNPFYDSSDNPYTRWLASTEGLQYSLHGLAAGAPPQDSSSKSPEPSADESPDNDKETPG 120
Query: 121 GGGDAGKKRKRRVLFSKAQTYELERRFRQQRYLSAPEREHLASLIRLTPTQVKIWFQNHR 180
GGGDAGKKRKRRVLFSKAQTYELERRFRQQRYLSAPEREHLASLIRLTPTQVKIWFQNHR
Sbjct: 121 GGGDAGKKRKRRVLFSKAQTYELERRFRQQRYLSAPEREHLASLIRLTPTQVKIWFQNHR 180
Query: 181 YKMKRARAEKGMEVTPLPSPRRVAVPVLVRDGKPCHALKAQDLAAATFQAGIPFSAYSAQ 240
YKMKRARAEKGMEVTPLPSPRRVAVPVLVRDGKPCHALKAQDLAAATFQAGIPFSAYSAQ
Sbjct: 181 YKMKRARAEKGMEVTPLPSPRRVAVPVLVRDGKPCHALKAQDLAAATFQAGIPFSAYSAQ 240
Query: 241 SLQHMQYNAQYSSASTPQYPTAHPLVQAQQWTW 273
SLQHMQYNAQYSSASTPQYPTAHPLVQAQQWTW
Sbjct: 241 SLQHMQYNAQYSSASTPQYPTAHPLVQAQQWTW 273
>gi|31377777 NK2 homeobox 8 [Homo sapiens]
Length = 239
Score = 151 bits (381), Expect = 7e-37
Identities = 103/254 (40%), Positives = 126/254 (49%), Gaps = 61/254 (24%)
Query: 4 TNTKTGFSVKDILDLPDTNDEEGSVAEGPEEENEGPEPAKRAGPLGQGALDAVQSLPLKN 63
T+ + F+V+ +LDLP+ ++ E E P+P
Sbjct: 3 TSGRLSFTVRSLLDLPE---QDAQHLPRREPEPRAPQP---------------------- 37
Query: 64 PFYDSSDNPYTRWLASTEGLQYSLHGLAAGAPPQDSSSKSPEPSADESPDNDKETPGGGG 123
+P WL S G S +SS ++ P + + P +PG
Sbjct: 38 -------DPCAAWLDSERGHYPS---------SDESSLETSPPDSSQRPSARPASPGS-- 79
Query: 124 DAGKKRKRRVLFSKAQTYELERRFRQQRYLSAPEREHLASLIRLTPTQVKIWFQNHRYKM 183
DA K++KRRVLFSKAQT ELERRFRQQRYLSAPERE LASL+RLTPTQVKIWFQNHRYK+
Sbjct: 80 DAEKRKKRRVLFSKAQTLELERRFRQQRYLSAPEREQLASLLRLTPTQVKIWFQNHRYKL 139
Query: 184 KRARAEKGMEVTPLPSP----------RRVAVPVLVRDGKPC--------HALKAQDLAA 225
KRARA E L + RRV VPVLVRDG+PC AQ+
Sbjct: 140 KRARAPGAAESPDLAASAELHAAPGLLRRVVVPVLVRDGQPCGGGGGGEVGTAAAQEKCG 199
Query: 226 ATFQAGIPFSAYSA 239
A A P Y A
Sbjct: 200 APPAAACPLPGYPA 213
>gi|157426823 NK2 homeobox 4 [Homo sapiens]
Length = 354
Score = 142 bits (358), Expect = 3e-34
Identities = 72/102 (70%), Positives = 79/102 (77%), Gaps = 11/102 (10%)
Query: 125 AGKKRKRRVLFSKAQTYELERRFRQQRYLSAPEREHLASLIRLTPTQVKIWFQNHRYKMK 184
A +RKRRVLFS+AQ YELERRF+QQ+YLSAPEREHLAS+I LTPTQVKIWFQNHRYKMK
Sbjct: 186 AAPRRKRRVLFSQAQVYELERRFKQQKYLSAPEREHLASMIHLTPTQVKIWFQNHRYKMK 245
Query: 185 RARAEK-----------GMEVTPLPSPRRVAVPVLVRDGKPC 215
R +K G P PSPRRVAVPVLV+DGKPC
Sbjct: 246 RQAKDKAAQQLQQEGGLGPPPPPPPSPRRVAVPVLVKDGKPC 287
>gi|148746211 NK2 transcription factor related, locus 3 [Homo
sapiens]
Length = 364
Score = 142 bits (357), Expect = 4e-34
Identities = 111/284 (39%), Positives = 138/284 (48%), Gaps = 50/284 (17%)
Query: 6 TKTGFSVKDILDLPDTNDE-EGSVAEGPEEENEGPEPAKRAGPLGQGALDAVQSLPLKNP 64
T T FSVKDIL+L + G+ + E + P A G D +
Sbjct: 8 TSTPFSVKDILNLEQQHQHFHGAHLQADLEHHFHSAPCMLAAAEGTQFSDGGEE------ 61
Query: 65 FYDSSDN----PYTRWLASTEGLQYSLHGLAAGAPP-------QDSSSKSPEPSADESPD 113
D D Y LA+ +G HG + P +DS S+ E +
Sbjct: 62 --DEEDEGEKLSYLNSLAAADG-----HGDSGLCPQGYVHTVLRDSCSEPKEHEEEPEVV 114
Query: 114 NDK-----------ETPGGGGDAGK--------KRKRRVLFSKAQTYELERRFRQQRYLS 154
D+ ET G A + +RK RVLFS+AQ +ELERRF+QQRYLS
Sbjct: 115 RDRSQKSCQLKKSLETAGDCKAAEESERPKPRSRRKPRVLFSQAQVFELERRFKQQRYLS 174
Query: 155 APEREHLASLIRLTPTQVKIWFQNHRYKMKRARAEKGMEV---TPLPSPRRVAVPVLVRD 211
APEREHLAS ++LT TQVKIWFQN RYK KR R +K +E+ P P PRRVAVPVLVRD
Sbjct: 175 APEREHLASSLKLTSTQVKIWFQNRRYKCKRQRQDKSLELGAHAPPPPPRRVAVPVLVRD 234
Query: 212 GKPCHALKAQDLAAATFQAGIPFSAYSAQSLQHMQYNAQYSSAS 255
GKPC AQ A + SAYS S Y ++A+
Sbjct: 235 GKPCVTPSAQAYGA---PYSVGASAYSYNSFPAYGYGNSAAAAA 275
>gi|210147470 NK2 transcription factor related, locus 6 [Homo
sapiens]
Length = 219
Score = 139 bits (351), Expect = 2e-33
Identities = 88/181 (48%), Positives = 105/181 (58%), Gaps = 8/181 (4%)
Query: 94 APPQDSSSKSPEPSADESPDNDKETPGGGGDAGKKRKRRVLFSKAQTYELERRFRQQRYL 153
A P ++ PE S D+ + A ++RK RVLFS+AQ LERRF+QQRYL
Sbjct: 16 ASPLGGGTRVPERGVGNSGDSVRGGRSEQPKARQRRKPRVLFSQAQVLALERRFKQQRYL 75
Query: 154 SAPEREHLASLIRLTPTQVKIWFQNHRYKMKRARAEKGMEVTPLP-SPRRVAVPVLVRDG 212
SAPEREHLAS ++LT TQVKIWFQN RYK KR R +K +E+ P +PRRVAVPVLVRDG
Sbjct: 76 SAPEREHLASALQLTSTQVKIWFQNRRYKCKRQRQDKSLELAGHPLTPRRVAVPVLVRDG 135
Query: 213 KPC--HALKAQDLAAATFQAGIPFSAYSAQSLQHMQYNAQYSS--ASTPQYPTAH-PLVQ 267
KPC A + A P+S Y S Y A Y + A P P H PL
Sbjct: 136 KPCLGPGPGAPAFPSPYSAAVSPYSCYGGYS--GAPYGAGYGTCYAGAPSGPAPHTPLAS 193
Query: 268 A 268
A
Sbjct: 194 A 194
>gi|118766339 thyroid transcription factor 1 isoform 1 [Homo
sapiens]
Length = 401
Score = 137 bits (344), Expect = 1e-32
Identities = 81/150 (54%), Positives = 95/150 (63%), Gaps = 29/150 (19%)
Query: 128 KRKRRVLFSKAQTYELERRFRQQRYLSAPEREHLASLIRLTPTQVKIWFQNHRYKMKRAR 187
+RKRRVLFS+AQ YELERRF+QQ+YLSAPEREHLAS+I LTPTQVKIWFQNHRYKMKR
Sbjct: 191 RRKRRVLFSQAQVYELERRFKQQKYLSAPEREHLASMIHLTPTQVKIWFQNHRYKMKRQA 250
Query: 188 AEKGMEV--------------TPLP--------SPRRVAVPVLVRDGKPCHALKAQDLAA 225
+K + T P SPRRVAVPVLV+DGKPC A A A
Sbjct: 251 KDKAAQQQLQQDSGGGGGGGGTGCPQQQQAQQQSPRRVAVPVLVKDGKPCQA-GAPAPGA 309
Query: 226 ATFQAGIPFSAYSAQSLQHMQYNAQYSSAS 255
A+ Q ++ Q QH AQ ++A+
Sbjct: 310 ASLQ------GHAQQQAQHQAQAAQAAAAA 333
>gi|4507715 thyroid transcription factor 1 isoform 2 [Homo sapiens]
Length = 371
Score = 137 bits (344), Expect = 1e-32
Identities = 81/150 (54%), Positives = 95/150 (63%), Gaps = 29/150 (19%)
Query: 128 KRKRRVLFSKAQTYELERRFRQQRYLSAPEREHLASLIRLTPTQVKIWFQNHRYKMKRAR 187
+RKRRVLFS+AQ YELERRF+QQ+YLSAPEREHLAS+I LTPTQVKIWFQNHRYKMKR
Sbjct: 161 RRKRRVLFSQAQVYELERRFKQQKYLSAPEREHLASMIHLTPTQVKIWFQNHRYKMKRQA 220
Query: 188 AEKGMEV--------------TPLP--------SPRRVAVPVLVRDGKPCHALKAQDLAA 225
+K + T P SPRRVAVPVLV+DGKPC A A A
Sbjct: 221 KDKAAQQQLQQDSGGGGGGGGTGCPQQQQAQQQSPRRVAVPVLVKDGKPCQA-GAPAPGA 279
Query: 226 ATFQAGIPFSAYSAQSLQHMQYNAQYSSAS 255
A+ Q ++ Q QH AQ ++A+
Sbjct: 280 ASLQ------GHAQQQAQHQAQAAQAAAAA 303
>gi|4758090 NK2 transcription factor related, locus 5 [Homo sapiens]
Length = 324
Score = 134 bits (336), Expect = 1e-31
Identities = 94/231 (40%), Positives = 123/231 (53%), Gaps = 29/231 (12%)
Query: 6 TKTGFSVKDILDLPDTNDEEGSVAEGPE-----EENEGP--------EPAKRAGPLGQGA 52
T T FSVKDIL+L ++ S+A E E P +P AGP
Sbjct: 8 TPTPFSVKDILNL---EQQQRSLAAAGELSARLEATLAPSSCMLAAFKPEAYAGPEA--- 61
Query: 53 LDAVQSLPLKNPFYDSSDNPYTRWLASTEGLQYSLHGLAAGAPPQDSSSKSPEPSADESP 112
A LP + +P A + + P +D ++ E A +
Sbjct: 62 --AAPGLPELRAELGRAPSPAKCASAFPAAPAFYPRAYSDPDPAKDPRAEKKELCALQKA 119
Query: 113 DNDKETPGGGGD---AGKKRKRRVLFSKAQTYELERRFRQQRYLSAPEREHLASLIRLTP 169
++T + A ++RK RVLFS+AQ YELERRF+QQRYLSAPER+ LAS+++LT
Sbjct: 120 VELEKTEADNAERPRARRRRKPRVLFSQAQVYELERRFKQQRYLSAPERDQLASVLKLTS 179
Query: 170 TQVKIWFQNHRYKMKRARAEKGMEVTPLPSP-----RRVAVPVLVRDGKPC 215
TQVKIWFQN RYK KR R ++ +E+ LP P RR+AVPVLVRDGKPC
Sbjct: 180 TQVKIWFQNRRYKCKRQRQDQTLELVGLPPPPPPPARRIAVPVLVRDGKPC 230
>gi|4502365 NK3 homeobox 2 [Homo sapiens]
Length = 333
Score = 97.4 bits (241), Expect = 1e-20
Identities = 83/231 (35%), Positives = 105/231 (45%), Gaps = 59/231 (25%)
Query: 21 TNDEEGSVAEGPE---------EENEGPEPAKRA-GPLGQGALDAVQSLPLKNPFYDSSD 70
T G AE PE EENE A G G G A SL L P +
Sbjct: 77 TRTAAGRTAESPEGWDSDSALSEENESRRRCADARGASGAGL--AGGSLSLGQPVCE--- 131
Query: 71 NPYTRWLASTEGLQYSLHGLAAGAPPQDSSSKSPEPSADESP--DNDKETP--------- 119
LA+++ L+ G + S S S D SP ++D P
Sbjct: 132 ------LAASKDLEEEAAG-------RSDSEMSASVSGDRSPRTEDDGVGPRGAHVSALC 178
Query: 120 ---GGGGDAG----------------KKRKRRVLFSKAQTYELERRFRQQRYLSAPEREH 160
GGGG +G +K++ R FS AQ +ELERRF QRYLS PER
Sbjct: 179 SGAGGGGGSGPAGVAEEEEEPAAPKPRKKRSRAAFSHAQVFELERRFNHQRYLSGPERAD 238
Query: 161 LASLIRLTPTQVKIWFQNHRYKMKRARAEKGMEVTPLPSPRRVAVPVLVRD 211
LA+ ++LT TQVKIWFQN RYK KR + + + P+ ++VAV VLVRD
Sbjct: 239 LAASLKLTETQVKIWFQNRRYKTKRRQMAADL-LASAPAAKKVAVKVLVRD 288
>gi|116805350 homeo box (H6 family) 1 [Homo sapiens]
Length = 348
Score = 87.4 bits (215), Expect = 1e-17
Identities = 76/226 (33%), Positives = 105/226 (46%), Gaps = 31/226 (13%)
Query: 31 GPEEENEGPEPAKRAGP-LGQGALDAVQSLPLKNPFYDSSDNPYTRWLASTEGLQYSLHG 89
GP GP P GP G A + P + Y +P T S E + G
Sbjct: 88 GPGALGLGPRPPPGPGPPFALGCGGAARWYPRAHGGYGGGLSPDTSDRDSPETGEEM--G 145
Query: 90 LAAGAPPQ------------DSSSKSPEPSADES------PDNDKETPGGGG-DAGKKRK 130
A GA P+ + +++ P +E+ P ET GG G G+K+K
Sbjct: 146 RAEGAWPRGPGPGAVQREAAELAARGPAAGTEEASELAEVPAAAGETRGGVGVGGGRKKK 205
Query: 131 RRVLFSKAQTYELERRFRQQRYLSAPEREHLASLIRLTPTQVKIWFQNHRYKMKRARAE- 189
R +FS++Q ++LE F +RYLS+ ER LA+ ++LT TQVKIWFQN R K KR A
Sbjct: 206 TRTVFSRSQVFQLESTFDLKRYLSSAERAGLAASLQLTETQVKIWFQNRRNKWKRQLAAE 265
Query: 190 -KGMEVTPLPSPRRVAVPVLVRDGKPCHALKAQDLAAATFQAGIPF 234
+ ++P + R V VPVL + P AAA A +PF
Sbjct: 266 LEAASLSPPGAQRLVRVPVLYHESPPA-------AAAAGPPATLPF 304
>gi|157743259 H6 family homeobox 3 [Homo sapiens]
Length = 357
Score = 80.1 bits (196), Expect = 2e-15
Identities = 74/247 (29%), Positives = 111/247 (44%), Gaps = 37/247 (14%)
Query: 25 EGSVAEGPEEENEGPEPAKRAGPLGQGALDAVQSLPLKNP---FYDSSDNPYTRWLA-ST 80
+ S A G + ++ PEP +A P + L K+P + SD+ ++ +
Sbjct: 142 DSSPASGTDRDS--PEPLLKADP-------DHKELDSKSPDEIILEESDSEESKKEGEAA 192
Query: 81 EGLQYSLHGLAAGAPPQDSSSKSPEPSADESPDNDKETPGGGGDAGKKRKRRVLFSKAQT 140
G + G AA P + K E S ++ P A +K+K R +FS++Q
Sbjct: 193 PGAAGASVGAAAATPGAEDWKKGAE-SPEKKP------------ACRKKKTRTVFSRSQV 239
Query: 141 YELERRFRQQRYLSAPEREHLASLIRLTPTQVKIWFQNHRYKMKRARAE--KGMEVTPLP 198
++LE F +RYLS+ ER LA+ + LT TQVKIWFQN R K KR A + ++
Sbjct: 240 FQLESTFDMKRYLSSSERAGLAASLHLTETQVKIWFQNRRNKWKRQLAAELEAANLSHAA 299
Query: 199 SPRRVAVPVLVRDGKPCHALKAQDLAAATFQAGIPFSAYSAQSLQHMQYNAQYSSASTPQ 258
+ R V VP+L + A+ AAA A +P S Q L + YS
Sbjct: 300 AQRIVRVPILYHENS-----AAEGAAAAAAGAPVPVS----QPLLTFPHPVYYSHPVVSS 350
Query: 259 YPTAHPL 265
P P+
Sbjct: 351 VPLLRPV 357
>gi|70608170 H6 family homeobox 2 [Homo sapiens]
Length = 273
Score = 78.2 bits (191), Expect = 7e-15
Identities = 62/195 (31%), Positives = 89/195 (45%), Gaps = 35/195 (17%)
Query: 23 DEEGSVAEGPEEENEGPEPA----KRAGPLGQGALDAVQSLPLKNPFYDSSDNPYTRWLA 78
D+ G +GP+ P P K +G G G L+ + PF S + +
Sbjct: 69 DQHGPKEQGPKHHPPIPFPCLGTPKGSGGSGPGGLE-------RTPFLSPSHSDFKE--- 118
Query: 79 STEGLQYSLHGLAAGAPPQDSSSKSPEPSADESPDNDKETPGGGGDAGKKRKRRVLFSKA 138
E L L AG SP P ++ D E G K+K R +FS++
Sbjct: 119 EKERL------LPAG---------SPSPGSERPRDGGAERQAGAA----KKKTRTVFSRS 159
Query: 139 QTYELERRFRQQRYLSAPEREHLASLIRLTPTQVKIWFQNHRYKMKRARAE--KGMEVTP 196
Q Y+LE F +RYLS+ ER LAS ++LT TQVK WFQN R K KR + + +
Sbjct: 160 QVYQLESTFDMKRYLSSSERACLASSLQLTETQVKTWFQNRRNKWKRQLSAELEAANMAH 219
Query: 197 LPSPRRVAVPVLVRD 211
+ V++P++ RD
Sbjct: 220 ASAQTLVSMPLVFRD 234
>gi|19923352 NK3 homeobox 1 [Homo sapiens]
Length = 234
Score = 78.2 bits (191), Expect = 7e-15
Identities = 36/58 (62%), Positives = 43/58 (74%)
Query: 128 KRKRRVLFSKAQTYELERRFRQQRYLSAPEREHLASLIRLTPTQVKIWFQNHRYKMKR 185
+++ R FS Q ELER+F Q+YLSAPER HLA ++LT TQVKIWFQN RYK KR
Sbjct: 124 QKRSRAAFSHTQVIELERKFSHQKYLSAPERAHLAKNLKLTETQVKIWFQNRRYKTKR 181
>gi|24497515 homeobox A3 isoform b [Homo sapiens]
Length = 285
Score = 74.7 bits (182), Expect = 8e-14
Identities = 43/111 (38%), Positives = 59/111 (53%), Gaps = 5/111 (4%)
Query: 97 QDSSSKSPEPSADESPDNDKETPGGGGDAGKKRKRRVLFSKAQTYELERRFRQQRYLSAP 156
Q++ K+ S+ ES DK PG ++ R ++ AQ ELE+ F RYL P
Sbjct: 6 QNTKQKTSSSSSGESCAGDKSPPG----QASSKRARTAYTSAQLVELEKEFHFNRYLCRP 61
Query: 157 EREHLASLIRLTPTQVKIWFQNHRYKMKRARAEKGMEVTP-LPSPRRVAVP 206
R +A+L+ LT Q+KIWFQN R K K+ + KGM + SP R VP
Sbjct: 62 RRVEMANLLNLTERQIKIWFQNRRMKYKKDQKGKGMLTSSGGQSPSRSPVP 112
>gi|24497513 homeobox A3 isoform a [Homo sapiens]
Length = 443
Score = 74.7 bits (182), Expect = 8e-14
Identities = 43/111 (38%), Positives = 59/111 (53%), Gaps = 5/111 (4%)
Query: 97 QDSSSKSPEPSADESPDNDKETPGGGGDAGKKRKRRVLFSKAQTYELERRFRQQRYLSAP 156
Q++ K+ S+ ES DK PG ++ R ++ AQ ELE+ F RYL P
Sbjct: 164 QNTKQKTSSSSSGESCAGDKSPPG----QASSKRARTAYTSAQLVELEKEFHFNRYLCRP 219
Query: 157 EREHLASLIRLTPTQVKIWFQNHRYKMKRARAEKGMEVTP-LPSPRRVAVP 206
R +A+L+ LT Q+KIWFQN R K K+ + KGM + SP R VP
Sbjct: 220 RRVEMANLLNLTERQIKIWFQNRRMKYKKDQKGKGMLTSSGGQSPSRSPVP 270
>gi|13562112 homeobox A3 isoform a [Homo sapiens]
Length = 443
Score = 74.7 bits (182), Expect = 8e-14
Identities = 43/111 (38%), Positives = 59/111 (53%), Gaps = 5/111 (4%)
Query: 97 QDSSSKSPEPSADESPDNDKETPGGGGDAGKKRKRRVLFSKAQTYELERRFRQQRYLSAP 156
Q++ K+ S+ ES DK PG ++ R ++ AQ ELE+ F RYL P
Sbjct: 164 QNTKQKTSSSSSGESCAGDKSPPG----QASSKRARTAYTSAQLVELEKEFHFNRYLCRP 219
Query: 157 EREHLASLIRLTPTQVKIWFQNHRYKMKRARAEKGMEVTP-LPSPRRVAVP 206
R +A+L+ LT Q+KIWFQN R K K+ + KGM + SP R VP
Sbjct: 220 RRVEMANLLNLTERQIKIWFQNRRMKYKKDQKGKGMLTSSGGQSPSRSPVP 270
>gi|45593144 gastrulation brain homeo box 2 [Homo sapiens]
Length = 348
Score = 73.9 bits (180), Expect = 1e-13
Identities = 42/101 (41%), Positives = 56/101 (55%), Gaps = 7/101 (6%)
Query: 116 KETPGGGGDAG------KKRKRRVLFSKAQTYELERRFRQQRYLSAPEREHLASLIRLTP 169
+ETP G AG K R+RR F+ Q ELE+ F ++YLS ER +A ++L+
Sbjct: 229 EETPPSSGAAGSTTSTGKNRRRRTAFTSEQLLELEKEFHCKKYLSLTERSQIAHALKLSE 288
Query: 170 TQVKIWFQNHRYKMKRARAEKGMEVTPLPSPR-RVAVPVLV 209
QVKIWFQN R K KR +A T PS ++ VP+ V
Sbjct: 289 VQVKIWFQNRRAKWKRVKAGNANSKTGEPSRNPKIVVPIPV 329
>gi|64225290 distal-less homeobox 1 isoform 1 [Homo sapiens]
Length = 255
Score = 73.6 bits (179), Expect = 2e-13
Identities = 43/99 (43%), Positives = 57/99 (57%), Gaps = 6/99 (6%)
Query: 99 SSSKSPEPSADESPDNDKETPGGGGDA-----GKK-RKRRVLFSKAQTYELERRFRQQRY 152
S+S + D D++K T GG+ GKK RK R ++S Q L RRF+Q +Y
Sbjct: 93 SASLAQSRLEDPGADSEKSTVVEGGEVRFNGKGKKIRKPRTIYSSLQLQALNRRFQQTQY 152
Query: 153 LSAPEREHLASLIRLTPTQVKIWFQNHRYKMKRARAEKG 191
L+ PER LA+ + LT TQVKIWFQN R K K+ + G
Sbjct: 153 LALPERAELAASLGLTQTQVKIWFQNKRSKFKKLMKQGG 191
>gi|4885185 distal-less homeobox 3 [Homo sapiens]
Length = 287
Score = 72.4 bits (176), Expect = 4e-13
Identities = 49/137 (35%), Positives = 68/137 (49%), Gaps = 23/137 (16%)
Query: 66 YDSSDNPYTRWLASTEGLQYSLHGLAA------------GAPPQDSSSKSPEPSADESPD 113
Y + NPYT Q++L+GLA GA + + +P + P
Sbjct: 56 YGQTVNPYTYHH------QFNLNGLAGTGAYSPKSEYTYGASYRQYGAYREQPLPAQDPV 109
Query: 114 NDKETPGG-----GGDAGKKRKRRVLFSKAQTYELERRFRQQRYLSAPEREHLASLIRLT 168
+ KE P G K RK R ++S Q L+RRF++ +YL+ PER LA+ + LT
Sbjct: 110 SVKEEPEAEVRMVNGKPKKVRKPRTIYSSYQLAALQRRFQKAQYLALPERAELAAQLGLT 169
Query: 169 PTQVKIWFQNHRYKMKR 185
TQVKIWFQN R K K+
Sbjct: 170 QTQVKIWFQNRRSKFKK 186
>gi|4885187 distal-less homeobox 5 [Homo sapiens]
Length = 289
Score = 72.4 bits (176), Expect = 4e-13
Identities = 54/154 (35%), Positives = 74/154 (48%), Gaps = 31/154 (20%)
Query: 66 YDSSDNPYTRWLASTEGLQYSLHGL--AAGAPP--------------QDSSSKSPEPSAD 109
Y + NPY QY HG+ +AG+ P Q + + PSA
Sbjct: 66 YGKALNPY----------QYQYHGVNGSAGSYPAKAYADYSYASSYHQYGGAYNRVPSAT 115
Query: 110 ESPDNDKETPGG---GGDAGKKRKRRVLFSKAQTYELERRFRQQRYLSAPEREHLASLIR 166
P+ + P G K RK R ++S Q L+RRF++ +YL+ PER LA+ +
Sbjct: 116 NQPEKEVTEPEVRMVNGKPKKVRKPRTIYSSFQLAALQRRFQKTQYLALPERAELAASLG 175
Query: 167 LTPTQVKIWFQNHRYKMKRARAEKGMEVTPLPSP 200
LT TQVKIWFQN R K+K+ K E+ P SP
Sbjct: 176 LTQTQVKIWFQNKRSKIKKIM--KNGEMPPEHSP 207
>gi|239742243 PREDICTED: HPX-153 homeobox [Homo sapiens]
Length = 411
Score = 72.0 bits (175), Expect = 5e-13
Identities = 57/174 (32%), Positives = 78/174 (44%), Gaps = 14/174 (8%)
Query: 17 DLPDTNDEEGSVAEGPEEEN-EGPEPAKRAG----PLGQGALDAVQSLPLKNPFYDSSDN 71
++PD DE+ E PE E G E A+ G G G A ++ D +
Sbjct: 152 EVPD--DEDDDEDEAPETEAARGAEEARGGGGGLGARGSGCQGAAETDASPGATVDEAAA 209
Query: 72 PYTRWLASTEGLQYSLHGLAAGAPPQDSSSKSPEPSADESPDNDKETPGGGGDAGKKRKR 131
P R + G GA + +P+ +A + K T G +GK R+
Sbjct: 210 PGPRENSPVA------QGPPGGAAAPGGAGTTPQGTATAAKPKRKRT-GSDSKSGKPRRA 262
Query: 132 RVLFSKAQTYELERRFRQQRYLSAPEREHLASLIRLTPTQVKIWFQNHRYKMKR 185
R F+ Q LE +F+ RYLS ER +LA + LT TQVKIWFQN R K K+
Sbjct: 263 RTAFTYEQLVALENKFKATRYLSVCERLNLALSLSLTETQVKIWFQNRRTKWKK 316
>gi|7706621 T-cell leukemia homeobox 2 [Homo sapiens]
Length = 284
Score = 71.6 bits (174), Expect = 7e-13
Identities = 51/156 (32%), Positives = 72/156 (46%), Gaps = 32/156 (20%)
Query: 39 PEPAKRA----GPLGQGALDAVQSLPLKNPFYDSSDNPYTRWLASTEGLQYSLHGLAAGA 94
P PA A GP G G + L P+ DS G +++ L A
Sbjct: 92 PPPAGGAPAVPGPSGLGGAGGLAGLTF--PWMDS-------------GRRFAKDRLTAAL 136
Query: 95 PPQDSSSKSPEPSADESPDNDKETPGGGGDAGKKRKRRVLFSKAQTYELERRFRQQRYLS 154
P + + P + +P K++K R FS++Q ELERRF +Q+YL+
Sbjct: 137 SPFSGTRRIGHPYQNRTPP-------------KRKKPRTSFSRSQVLELERRFLRQKYLA 183
Query: 155 APEREHLASLIRLTPTQVKIWFQNHRYKMKRARAEK 190
+ ER LA +R+T QVK WFQN R K +R AE+
Sbjct: 184 SAERAALAKALRMTDAQVKTWFQNRRTKWRRQTAEE 219
>gi|4758168 distal-less homeobox 2 [Homo sapiens]
Length = 328
Score = 71.2 bits (173), Expect = 9e-13
Identities = 38/86 (44%), Positives = 51/86 (59%)
Query: 100 SSKSPEPSADESPDNDKETPGGGGDAGKKRKRRVLFSKAQTYELERRFRQQRYLSAPERE 159
+S SP + E D + E G K RK R ++S Q L+RRF++ +YL+ PER
Sbjct: 124 TSSSPANNEPEKEDLEPEIRIVNGKPKKVRKPRTIYSSFQLAALQRRFQKTQYLALPERA 183
Query: 160 HLASLIRLTPTQVKIWFQNHRYKMKR 185
LA+ + LT TQVKIWFQN R K K+
Sbjct: 184 ELAASLGLTQTQVKIWFQNRRSKFKK 209
>gi|239753784 PREDICTED: NK1 homeobox 1 [Homo sapiens]
Length = 814
Score = 71.2 bits (173), Expect = 9e-13
Identities = 57/174 (32%), Positives = 78/174 (44%), Gaps = 14/174 (8%)
Query: 17 DLPDTNDEEGSVAEGPEEEN-EGPEPAKRAG----PLGQGALDAVQSLPLKNPFYDSSDN 71
++PD DE+ E PE E G E A+ G G G A ++ D +
Sbjct: 555 EVPD--DEDDDEDEAPETEAARGAEEARGGGGGLGARGSGCQGAAETDASPGATVDEAAA 612
Query: 72 PYTRWLASTEGLQYSLHGLAAGAPPQDSSSKSPEPSADESPDNDKETPGGGGDAGKKRKR 131
P R + G GA + +P+ +A + K T G +GK R+
Sbjct: 613 PGPRENSPVAP------GPPGGAAAPGGAGTTPQGTATAAKPKRKRT-GSDSKSGKPRRA 665
Query: 132 RVLFSKAQTYELERRFRQQRYLSAPEREHLASLIRLTPTQVKIWFQNHRYKMKR 185
R F+ Q LE +F+ RYLS ER +LA + LT TQVKIWFQN R K K+
Sbjct: 666 RTAFTYEQLVALENKFKATRYLSVCERLNLALSLSLTETQVKIWFQNRRTKWKK 719
>gi|23097236 homeobox A9 [Homo sapiens]
Length = 272
Score = 70.1 bits (170), Expect = 2e-12
Identities = 43/122 (35%), Positives = 59/122 (48%), Gaps = 17/122 (13%)
Query: 86 SLHGLAAGAPPQDSSSKSPEPSADESPDNDKETPGGGGD--------------AGKKRKR 131
SL A G+PP D + +PS +N+ E GG A RK+
Sbjct: 153 SLTDYACGSPPVD---REKQPSEGAFSENNAENESGGDKPPIDPNNPAANWLHARSTRKK 209
Query: 132 RVLFSKAQTYELERRFRQQRYLSAPEREHLASLIRLTPTQVKIWFQNHRYKMKRARAEKG 191
R ++K QT ELE+ F YL+ R +A L+ LT QVKIWFQN R KMK+ ++
Sbjct: 210 RCPYTKHQTLELEKEFLFNMYLTRDRRYEVARLLNLTERQVKIWFQNRRMKMKKINKDRA 269
Query: 192 ME 193
+
Sbjct: 270 KD 271
>gi|82659115 distal-less homeobox 6 [Homo sapiens]
Length = 265
Score = 69.3 bits (168), Expect = 3e-12
Identities = 56/158 (35%), Positives = 78/158 (49%), Gaps = 17/158 (10%)
Query: 63 NPFYDSSDNPYT-RWLASTEGLQYSLHGLAAGAPPQDSSSKSPEPSADESPDNDKETPGG 121
+P+ N Y R LA+ + +S H + +SS + + D++ D K T
Sbjct: 70 SPYASGGGNSYNHRSLAAYPYMSHSQH--SPYLQSYHNSSAAAQTRGDDT-DQQKTTVIE 126
Query: 122 GGDA-----GKK-RKRRVLFSKAQTYELERRFRQQRYLSAPEREHLASLIRLTPTQVKIW 175
G+ GKK RK R ++S Q L RF+Q +YL+ PER LA+ + LT TQVKIW
Sbjct: 127 NGEIRFNGKGKKIRKPRTIYSSLQLQALNHRFQQTQYLALPERAELAASLGLTQTQVKIW 186
Query: 176 FQNHRYKMKR--ARAEKGMEVTPLP-----SPRRVAVP 206
FQN R K K+ + E PL SPR A+P
Sbjct: 187 FQNKRSKFKKLLKQGSNPHESDPLQGSAALSPRSPALP 224
>gi|121114296 caudal type homeobox 1 [Homo sapiens]
Length = 265
Score = 69.3 bits (168), Expect = 3e-12
Identities = 47/137 (34%), Positives = 63/137 (45%), Gaps = 27/137 (19%)
Query: 90 LAAGAPPQDSSSKSPE-------------PSADESPDNDKETP----------GGGGDAG 126
LA G PP S +P P SP + TP GGGG +G
Sbjct: 90 LAFGPPPDFSPVPAPPGPGPGLLAQPLGGPGTPSSPGAQRPTPYEWMRRSVAAGGGGGSG 149
Query: 127 KKR---KRRVLFSKAQTYELERRFRQQRYLSAPEREHLASLIRLTPTQVKIWFQNHRYKM 183
K R K RV+++ Q ELE+ F RY++ + LA+ + LT QVKIWFQN R K
Sbjct: 150 KTRTKDKYRVVYTDHQRLELEKEFHYSRYITIRRKSELAANLGLTERQVKIWFQNRRAKE 209
Query: 184 KRARAEKGMEVTPLPSP 200
++ +K + P P P
Sbjct: 210 RKVNKKKQQQQQP-PQP 225
>gi|19923391 homeobox D3 [Homo sapiens]
Length = 432
Score = 68.9 bits (167), Expect = 4e-12
Identities = 42/107 (39%), Positives = 59/107 (55%), Gaps = 7/107 (6%)
Query: 97 QDSSSKSPEPSADESPDNDKETPGGGGDAGKKRKRRVLFSKAQTYELERRFRQQRYLSAP 156
Q+S K+ +A ES + DK PG ++ R ++ AQ ELE+ F RYL P
Sbjct: 169 QNSKQKNSCATAGESCE-DKSPPGPAS-----KRVRTAYTSAQLVELEKEFHFNRYLCRP 222
Query: 157 EREHLASLIRLTPTQVKIWFQNHRYKMKRARAEKGMEVTPL-PSPRR 202
R +A+L+ LT Q+KIWFQN R K K+ + KG+ +P SP R
Sbjct: 223 RRVEMANLLNLTERQIKIWFQNRRMKYKKDQKAKGILHSPASQSPER 269
>gi|20143962 distal-less homeobox 4 isoform a [Homo sapiens]
Length = 240
Score = 68.9 bits (167), Expect = 4e-12
Identities = 52/156 (33%), Positives = 72/156 (46%), Gaps = 13/156 (8%)
Query: 39 PEPAKRAG-PLGQGALDAVQ-SLPLKNPF-------YDSSDNPYTRWLASTEGLQYSLHG 89
P P+ A PLG A +L P+ Y NP +L+ + S
Sbjct: 23 PVPSVAAAYPLGLSPTTAASPNLSYSRPYGHLLSYPYTEPANPGDSYLSCQQPAALSQPL 82
Query: 90 LAAGAPPQDSSSKSPEPSADESPDNDKETPGGGGDAGKKRKRRVLFSKAQTYELERRFRQ 149
PQ+ + S +P SP+ + P A K RK R ++S Q L +RF+
Sbjct: 83 CGPAEHPQELEADSEKPRL--SPEPSERRPQA--PAKKLRKPRTIYSSLQLQHLNQRFQH 138
Query: 150 QRYLSAPEREHLASLIRLTPTQVKIWFQNHRYKMKR 185
+YL+ PER LA+ + LT TQVKIWFQN R K K+
Sbjct: 139 TQYLALPERAQLAAQLGLTQTQVKIWFQNKRSKYKK 174
>gi|149588930 gastrulation brain homeo box 1 [Homo sapiens]
Length = 363
Score = 68.9 bits (167), Expect = 4e-12
Identities = 38/94 (40%), Positives = 53/94 (56%), Gaps = 3/94 (3%)
Query: 118 TPGGGGDAGKKRKRRVLFSKAQTYELERRFRQQRYLSAPEREHLASLIRLTPTQVKIWFQ 177
T G GK R+RR F+ Q ELE+ F ++YLS ER +A ++L+ QVKIWFQ
Sbjct: 251 TAGVTAPGGKSRRRRTAFTSEQLLELEKEFHCKKYLSLTERSQIAHALKLSEVQVKIWFQ 310
Query: 178 NHRYKMKRARA--EKGMEVTPLPSPRRVAVPVLV 209
N R K KR +A P+ +P ++ VP+ V
Sbjct: 311 NRRAKWKRIKAGNVSSRSGEPVRNP-KIVVPIPV 343
Database: hs.faa
Posted date: Aug 4, 2009 4:42 PM
Number of letters in database: 18,247,518
Number of sequences in database: 37,866
Lambda K H
0.311 0.128 0.378
Gapped
Lambda K H
0.267 0.0410 0.140
Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Hits to DB: 12,316,417
Number of Sequences: 37866
Number of extensions: 652312
Number of successful extensions: 3905
Number of sequences better than 10.0: 30
Number of HSP's better than 10.0 without gapping: 290
Number of HSP's successfully gapped in prelim test: 87
Number of HSP's that attempted gapping in prelim test: 3394
Number of HSP's gapped (non-prelim): 561
length of query: 273
length of database: 18,247,518
effective HSP length: 101
effective length of query: 172
effective length of database: 14,423,052
effective search space: 2480764944
effective search space used: 2480764944
T: 11
A: 40
X1: 16 ( 7.2 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 42 (21.8 bits)
S2: 61 (28.1 bits)
Search results were obtained with NCBI BLAST and RefSeq entries.
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Guide to the Human Genome
Copyright © 2010 by Stewart Scherer. All rights reserved.