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Search of human proteins with 4504851
BLASTP 2.2.11 [Jun-05-2005]
Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer,
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997),
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs", Nucleic Acids Res. 25:3389-3402.
Query= gi|4504851 potassium channel, subfamily K, member 5 [Homo
sapiens]
(499 letters)
Database: hs.faa
37,866 sequences; 18,247,518 total letters
Searching..................................................done
Score E
Sequences producing significant alignments: (bits) Value
gi|4504851 potassium channel, subfamily K, member 5 [Homo sapiens] 1011 0.0
gi|205360983 potassium channel, subfamily K, member 16 isoform 3... 194 2e-49
gi|14149764 potassium channel, subfamily K, member 16 isoform 2 ... 194 2e-49
gi|20143946 potassium channel, subfamily K, member 10 isoform 3 ... 178 9e-45
gi|20143944 potassium channel, subfamily K, member 10 isoform 2 ... 178 9e-45
gi|10863961 potassium channel, subfamily K, member 10 isoform 1 ... 178 9e-45
gi|17025230 potassium channel, subfamily K, member 17 isoform 1 ... 178 1e-44
gi|205360973 potassium channel, subfamily K, member 16 isoform 4... 163 4e-40
gi|205360971 potassium channel, subfamily K, member 16 isoform 1... 162 5e-40
gi|14589851 potassium channel, subfamily K, member 2 isoform b [... 162 7e-40
gi|126365795 potassium channel, subfamily K, member 2 isoform c ... 162 7e-40
gi|62912487 potassium channel, subfamily K, member 2 isoform a [... 162 7e-40
gi|15718767 TRAAK [Homo sapiens] 162 9e-40
gi|205361107 potassium channel, subfamily K, member 17 isoform 2... 141 1e-33
gi|4504847 potassium channel, subfamily K, member 1 [Homo sapiens] 133 3e-31
gi|4758624 potassium channel, subfamily K, member 6 [Homo sapiens] 127 2e-29
gi|4504849 potassium channel, subfamily K, member 3 [Homo sapiens] 120 4e-27
gi|11641275 potassium family, subfamily K, member 15 [Homo sapiens] 118 1e-26
gi|7706135 potassium channel, subfamily K, member 9 [Homo sapiens] 116 4e-26
gi|16306555 potassium channel, subfamily K, member 13 [Homo sapi... 96 8e-20
gi|11545761 potassium channel, subfamily K, member 12 [Homo sapi... 92 8e-19
gi|5031821 potassium channel, subfamily K, member 7 isoform C [H... 81 3e-15
gi|16118231 potassium channel, subfamily K, member 7 isoform A [... 81 3e-15
gi|16118235 potassium channel, subfamily K, member 7 isoform B [... 81 3e-15
gi|16118233 potassium channel, subfamily K, member 7 isoform B [... 81 3e-15
gi|32469495 potassium channel, subfamily K, member 18 [Homo sapi... 52 2e-06
gi|238624132 large conductance calcium-activated potassium chann... 45 2e-04
gi|238624130 large conductance calcium-activated potassium chann... 45 2e-04
gi|62388890 large conductance calcium-activated potassium channe... 45 2e-04
gi|26638650 large conductance calcium-activated potassium channe... 45 2e-04
>gi|4504851 potassium channel, subfamily K, member 5 [Homo sapiens]
Length = 499
Score = 1011 bits (2613), Expect = 0.0
Identities = 499/499 (100%), Positives = 499/499 (100%)
Query: 1 MVDRGPLLTSAIIFYLAIGAAIFEVLEEPHWKEAKKNYYTQKLHLLKEFPCLGQEGLDKI 60
MVDRGPLLTSAIIFYLAIGAAIFEVLEEPHWKEAKKNYYTQKLHLLKEFPCLGQEGLDKI
Sbjct: 1 MVDRGPLLTSAIIFYLAIGAAIFEVLEEPHWKEAKKNYYTQKLHLLKEFPCLGQEGLDKI 60
Query: 61 LEVVSDAAGQGVAITGNQTFNNWNWPNAMIFAATVITTIGYGNVAPKTPAGRLFCVFYGL 120
LEVVSDAAGQGVAITGNQTFNNWNWPNAMIFAATVITTIGYGNVAPKTPAGRLFCVFYGL
Sbjct: 61 LEVVSDAAGQGVAITGNQTFNNWNWPNAMIFAATVITTIGYGNVAPKTPAGRLFCVFYGL 120
Query: 121 FGVPLCLTWISALGKFFGGRAKRLGQFLTKRGVSLRKAQITCTVIFIVWGVLVHLVIPPF 180
FGVPLCLTWISALGKFFGGRAKRLGQFLTKRGVSLRKAQITCTVIFIVWGVLVHLVIPPF
Sbjct: 121 FGVPLCLTWISALGKFFGGRAKRLGQFLTKRGVSLRKAQITCTVIFIVWGVLVHLVIPPF 180
Query: 181 VFMVTEGWNYIEGLYYSFITISTIGFGDFVAGVNPSANYHALYRYFVELWIYLGLAWLSL 240
VFMVTEGWNYIEGLYYSFITISTIGFGDFVAGVNPSANYHALYRYFVELWIYLGLAWLSL
Sbjct: 181 VFMVTEGWNYIEGLYYSFITISTIGFGDFVAGVNPSANYHALYRYFVELWIYLGLAWLSL 240
Query: 241 FVNWKVSMFVEVHKAIKKRRRRRKESFESSPHSRKALQVKGSTASKDVNIFSFLSKKEET 300
FVNWKVSMFVEVHKAIKKRRRRRKESFESSPHSRKALQVKGSTASKDVNIFSFLSKKEET
Sbjct: 241 FVNWKVSMFVEVHKAIKKRRRRRKESFESSPHSRKALQVKGSTASKDVNIFSFLSKKEET 300
Query: 301 YNDLIKQIGKKAMKTSGGGETGPGPGLGPQGGGLPALPPSLVPLVVYSKNRVPTLEEVSQ 360
YNDLIKQIGKKAMKTSGGGETGPGPGLGPQGGGLPALPPSLVPLVVYSKNRVPTLEEVSQ
Sbjct: 301 YNDLIKQIGKKAMKTSGGGETGPGPGLGPQGGGLPALPPSLVPLVVYSKNRVPTLEEVSQ 360
Query: 361 TLRSKGHVSRSPDEEAVARAPEDSSPAPEVFMNQLDRISEECEPWDAQDYHPLIFQDASI 420
TLRSKGHVSRSPDEEAVARAPEDSSPAPEVFMNQLDRISEECEPWDAQDYHPLIFQDASI
Sbjct: 361 TLRSKGHVSRSPDEEAVARAPEDSSPAPEVFMNQLDRISEECEPWDAQDYHPLIFQDASI 420
Query: 421 TFVNTEAGLSDEETSKSSLEDNLAGEESPQQGAEAKAPLNMGEFPSSSESTFTSTESELS 480
TFVNTEAGLSDEETSKSSLEDNLAGEESPQQGAEAKAPLNMGEFPSSSESTFTSTESELS
Sbjct: 421 TFVNTEAGLSDEETSKSSLEDNLAGEESPQQGAEAKAPLNMGEFPSSSESTFTSTESELS 480
Query: 481 VPYEQLMNEYNKANSPKGT 499
VPYEQLMNEYNKANSPKGT
Sbjct: 481 VPYEQLMNEYNKANSPKGT 499
>gi|205360983 potassium channel, subfamily K, member 16 isoform 3
[Homo sapiens]
Length = 294
Score = 194 bits (493), Expect = 2e-49
Identities = 97/238 (40%), Positives = 152/238 (63%), Gaps = 3/238 (1%)
Query: 6 PLLTSAIIFYLAIGAAIFEVLEEPHWKEAKKNYYTQKLHLLKEFPCLGQEGLDKILEVVS 65
PLL A + YL +GA IF++LE +++ + +KL L+ + CL Q +++ ++V+
Sbjct: 16 PLLL-AYVCYLLLGATIFQLLERQAEAQSRDQFQLEKLRFLENYTCLDQWAMEQFVQVIM 74
Query: 66 DAAGQGVAITGNQTF-NNWNWPNAMIFAATVITTIGYGNVAPKTPAGRLFCVFYGLFGVP 124
+A +GV GN T +NW++ ++ FA TV+TTIGYGN+AP T AG++FCVFY L G+P
Sbjct: 75 EAWVKGVNPKGNSTNPSNWDFGSSFFFAGTVVTTIGYGNLAPSTEAGQVFCVFYALLGIP 134
Query: 125 LCLTWISALGKFFGGRAKRLGQFLTKRGVSLRKAQITCTVIFIVWGVLVHLVIPPFVFMV 184
L + +++ LG + ++ + S + Q+ +F+ G LV L+ PP VF
Sbjct: 135 LNVIFLNHLGTGLRAHLAAIERWEDRPRRS-QVLQVLGLALFLTLGTLVILIFPPMVFSH 193
Query: 185 TEGWNYIEGLYYSFITISTIGFGDFVAGVNPSANYHALYRYFVELWIYLGLAWLSLFV 242
EGW++ EG Y++FIT+STIGFGD+V G +PS +Y ++YR +WI LGLAWL+L +
Sbjct: 194 VEGWSFSEGFYFAFITLSTIGFGDYVVGTDPSKHYISVYRSLAAIWILLGLAWLALIL 251
>gi|14149764 potassium channel, subfamily K, member 16 isoform 2
[Homo sapiens]
Length = 309
Score = 194 bits (493), Expect = 2e-49
Identities = 97/238 (40%), Positives = 152/238 (63%), Gaps = 3/238 (1%)
Query: 6 PLLTSAIIFYLAIGAAIFEVLEEPHWKEAKKNYYTQKLHLLKEFPCLGQEGLDKILEVVS 65
PLL A + YL +GA IF++LE +++ + +KL L+ + CL Q +++ ++V+
Sbjct: 16 PLLL-AYVCYLLLGATIFQLLERQAEAQSRDQFQLEKLRFLENYTCLDQWAMEQFVQVIM 74
Query: 66 DAAGQGVAITGNQTF-NNWNWPNAMIFAATVITTIGYGNVAPKTPAGRLFCVFYGLFGVP 124
+A +GV GN T +NW++ ++ FA TV+TTIGYGN+AP T AG++FCVFY L G+P
Sbjct: 75 EAWVKGVNPKGNSTNPSNWDFGSSFFFAGTVVTTIGYGNLAPSTEAGQVFCVFYALLGIP 134
Query: 125 LCLTWISALGKFFGGRAKRLGQFLTKRGVSLRKAQITCTVIFIVWGVLVHLVIPPFVFMV 184
L + +++ LG + ++ + S + Q+ +F+ G LV L+ PP VF
Sbjct: 135 LNVIFLNHLGTGLRAHLAAIERWEDRPRRS-QVLQVLGLALFLTLGTLVILIFPPMVFSH 193
Query: 185 TEGWNYIEGLYYSFITISTIGFGDFVAGVNPSANYHALYRYFVELWIYLGLAWLSLFV 242
EGW++ EG Y++FIT+STIGFGD+V G +PS +Y ++YR +WI LGLAWL+L +
Sbjct: 194 VEGWSFSEGFYFAFITLSTIGFGDYVVGTDPSKHYISVYRSLAAIWILLGLAWLALIL 251
>gi|20143946 potassium channel, subfamily K, member 10 isoform 3
[Homo sapiens]
Length = 543
Score = 178 bits (452), Expect = 9e-45
Identities = 89/243 (36%), Positives = 138/243 (56%), Gaps = 10/243 (4%)
Query: 12 IIFYLAIGAAIFEVLEEPHWKEAKKNYYTQKLHLLKEFPCLGQEGLDKILEVVSDAAGQG 71
++ YL G +F LE+P K +K L++ C+ + L+ +++ DA G
Sbjct: 84 VVVYLVTGGLVFRALEQPFESSQKNTIALEKAEFLRDHVCVSPQELETLIQHALDADNAG 143
Query: 72 VAITGNQTFNNWNWP--NAMIFAATVITTIGYGNVAPKTPAGRLFCVFYGLFGVPLCLTW 129
V+ GN + N+ +W +A FA TVITTIGYGN+AP T G++FC+ Y +FG+PL
Sbjct: 144 VSPIGNSSNNSSHWDLGSAFFFAGTVITTIGYGNIAPSTEGGKIFCILYAIFGIPLFGFL 203
Query: 130 ISA----LGKFFGGRAKRLGQFLTKRGVSLRKAQITCTVIFIVWGVLVHLVIPPFVFMVT 185
++ LG FG R+ + K+ VS K ++ T++FI+ G +V + IP +F
Sbjct: 204 LAGIGDQLGTIFGKSIARVEKVFRKKQVSQTKIRVISTILFILAGCIVFVTIPAVIFKYI 263
Query: 186 EGWNYIEGLYYSFITISTIGFGDFVAGVNPSANYHALYRYFVELWIYLGLAW----LSLF 241
EGW +E +Y+ +T++T+GFGDFVAG N NY Y+ V WI +GLA+ LS+
Sbjct: 264 EGWTALESIYFVVVTLTTVGFGDFVAGGNAGINYREWYKPLVWFWILVGLAYFAAVLSMI 323
Query: 242 VNW 244
+W
Sbjct: 324 GDW 326
>gi|20143944 potassium channel, subfamily K, member 10 isoform 2
[Homo sapiens]
Length = 543
Score = 178 bits (452), Expect = 9e-45
Identities = 89/243 (36%), Positives = 138/243 (56%), Gaps = 10/243 (4%)
Query: 12 IIFYLAIGAAIFEVLEEPHWKEAKKNYYTQKLHLLKEFPCLGQEGLDKILEVVSDAAGQG 71
++ YL G +F LE+P K +K L++ C+ + L+ +++ DA G
Sbjct: 84 VVVYLVTGGLVFRALEQPFESSQKNTIALEKAEFLRDHVCVSPQELETLIQHALDADNAG 143
Query: 72 VAITGNQTFNNWNWP--NAMIFAATVITTIGYGNVAPKTPAGRLFCVFYGLFGVPLCLTW 129
V+ GN + N+ +W +A FA TVITTIGYGN+AP T G++FC+ Y +FG+PL
Sbjct: 144 VSPIGNSSNNSSHWDLGSAFFFAGTVITTIGYGNIAPSTEGGKIFCILYAIFGIPLFGFL 203
Query: 130 ISA----LGKFFGGRAKRLGQFLTKRGVSLRKAQITCTVIFIVWGVLVHLVIPPFVFMVT 185
++ LG FG R+ + K+ VS K ++ T++FI+ G +V + IP +F
Sbjct: 204 LAGIGDQLGTIFGKSIARVEKVFRKKQVSQTKIRVISTILFILAGCIVFVTIPAVIFKYI 263
Query: 186 EGWNYIEGLYYSFITISTIGFGDFVAGVNPSANYHALYRYFVELWIYLGLAW----LSLF 241
EGW +E +Y+ +T++T+GFGDFVAG N NY Y+ V WI +GLA+ LS+
Sbjct: 264 EGWTALESIYFVVVTLTTVGFGDFVAGGNAGINYREWYKPLVWFWILVGLAYFAAVLSMI 323
Query: 242 VNW 244
+W
Sbjct: 324 GDW 326
>gi|10863961 potassium channel, subfamily K, member 10 isoform 1
[Homo sapiens]
Length = 538
Score = 178 bits (452), Expect = 9e-45
Identities = 89/243 (36%), Positives = 138/243 (56%), Gaps = 10/243 (4%)
Query: 12 IIFYLAIGAAIFEVLEEPHWKEAKKNYYTQKLHLLKEFPCLGQEGLDKILEVVSDAAGQG 71
++ YL G +F LE+P K +K L++ C+ + L+ +++ DA G
Sbjct: 79 VVVYLVTGGLVFRALEQPFESSQKNTIALEKAEFLRDHVCVSPQELETLIQHALDADNAG 138
Query: 72 VAITGNQTFNNWNWP--NAMIFAATVITTIGYGNVAPKTPAGRLFCVFYGLFGVPLCLTW 129
V+ GN + N+ +W +A FA TVITTIGYGN+AP T G++FC+ Y +FG+PL
Sbjct: 139 VSPIGNSSNNSSHWDLGSAFFFAGTVITTIGYGNIAPSTEGGKIFCILYAIFGIPLFGFL 198
Query: 130 ISA----LGKFFGGRAKRLGQFLTKRGVSLRKAQITCTVIFIVWGVLVHLVIPPFVFMVT 185
++ LG FG R+ + K+ VS K ++ T++FI+ G +V + IP +F
Sbjct: 199 LAGIGDQLGTIFGKSIARVEKVFRKKQVSQTKIRVISTILFILAGCIVFVTIPAVIFKYI 258
Query: 186 EGWNYIEGLYYSFITISTIGFGDFVAGVNPSANYHALYRYFVELWIYLGLAW----LSLF 241
EGW +E +Y+ +T++T+GFGDFVAG N NY Y+ V WI +GLA+ LS+
Sbjct: 259 EGWTALESIYFVVVTLTTVGFGDFVAGGNAGINYREWYKPLVWFWILVGLAYFAAVLSMI 318
Query: 242 VNW 244
+W
Sbjct: 319 GDW 321
>gi|17025230 potassium channel, subfamily K, member 17 isoform 1
[Homo sapiens]
Length = 332
Score = 178 bits (451), Expect = 1e-44
Identities = 94/264 (35%), Positives = 141/264 (53%), Gaps = 1/264 (0%)
Query: 7 LLTSAIIFYLAIGAAIFEVLEEPHWKEAKKNYYTQKLHLLKEFPCLGQEGLDKILEVVSD 66
LL A + YLA+G +F LE +++ +++ K LL+ F CL + LD ++ V
Sbjct: 24 LLLLAYLAYLALGTGVFWTLEGRAAQDSSRSFQRDKWELLQNFTCLDRPALDSLIRDVVQ 83
Query: 67 AAGQGVAITGNQT-FNNWNWPNAMIFAATVITTIGYGNVAPKTPAGRLFCVFYGLFGVPL 125
A G ++ N T W + F+ + ITTIGYGN++P T A RLFC+F+ L G+PL
Sbjct: 84 AYKNGASLLSNTTSMGRWELVGSFFFSVSTITTIGYGNLSPNTMAARLFCIFFALVGIPL 143
Query: 126 CLTWISALGKFFGGRAKRLGQFLTKRGVSLRKAQITCTVIFIVWGVLVHLVIPPFVFMVT 185
L ++ LG L KA+ ++ G+L+ L++PP +F
Sbjct: 144 NLVVLNRLGHLMQQGVNHWASRLGGTWQDPDKARWLAGSGALLSGLLLFLLLPPLLFSHM 203
Query: 186 EGWNYIEGLYYSFITISTIGFGDFVAGVNPSANYHALYRYFVELWIYLGLAWLSLFVNWK 245
EGW+Y EG Y++FIT+ST+GFGD+V G+NPS Y Y+ V LWI G+AWL+L +
Sbjct: 204 EGWSYTEGFYFAFITLSTVGFGDYVIGMNPSQRYPLWYKNMVSLWILFGMAWLALIIKLI 263
Query: 246 VSMFVEVHKAIKKRRRRRKESFES 269
+S + KE F+S
Sbjct: 264 LSQLETPGRVCSCCHHSSKEDFKS 287
>gi|205360973 potassium channel, subfamily K, member 16 isoform 4
[Homo sapiens]
Length = 262
Score = 163 bits (412), Expect = 4e-40
Identities = 83/209 (39%), Positives = 131/209 (62%), Gaps = 3/209 (1%)
Query: 6 PLLTSAIIFYLAIGAAIFEVLEEPHWKEAKKNYYTQKLHLLKEFPCLGQEGLDKILEVVS 65
PLL A + YL +GA IF++LE +++ + +KL L+ + CL Q +++ ++V+
Sbjct: 16 PLLL-AYVCYLLLGATIFQLLERQAEAQSRDQFQLEKLRFLENYTCLDQWAMEQFVQVIM 74
Query: 66 DAAGQGVAITGNQTF-NNWNWPNAMIFAATVITTIGYGNVAPKTPAGRLFCVFYGLFGVP 124
+A +GV GN T +NW++ ++ FA TV+TTIGYGN+AP T AG++FCVFY L G+P
Sbjct: 75 EAWVKGVNPKGNSTNPSNWDFGSSFFFAGTVVTTIGYGNLAPSTEAGQVFCVFYALLGIP 134
Query: 125 LCLTWISALGKFFGGRAKRLGQFLTKRGVSLRKAQITCTVIFIVWGVLVHLVIPPFVFMV 184
L + +++ LG + ++ R + Q+ +F+ G LV L+ PP VF
Sbjct: 135 LNVIFLNHLGTGLRAHLAAIERW-EDRPRRSQVLQVLGLALFLTLGTLVILIFPPMVFSH 193
Query: 185 TEGWNYIEGLYYSFITISTIGFGDFVAGV 213
EGW++ EG Y++FIT+STIGFGD+V G+
Sbjct: 194 VEGWSFSEGFYFAFITLSTIGFGDYVVGL 222
>gi|205360971 potassium channel, subfamily K, member 16 isoform 1
[Homo sapiens]
Length = 322
Score = 162 bits (411), Expect = 5e-40
Identities = 83/208 (39%), Positives = 130/208 (62%), Gaps = 3/208 (1%)
Query: 6 PLLTSAIIFYLAIGAAIFEVLEEPHWKEAKKNYYTQKLHLLKEFPCLGQEGLDKILEVVS 65
PLL A + YL +GA IF++LE +++ + +KL L+ + CL Q +++ ++V+
Sbjct: 16 PLLL-AYVCYLLLGATIFQLLERQAEAQSRDQFQLEKLRFLENYTCLDQWAMEQFVQVIM 74
Query: 66 DAAGQGVAITGNQTF-NNWNWPNAMIFAATVITTIGYGNVAPKTPAGRLFCVFYGLFGVP 124
+A +GV GN T +NW++ ++ FA TV+TTIGYGN+AP T AG++FCVFY L G+P
Sbjct: 75 EAWVKGVNPKGNSTNPSNWDFGSSFFFAGTVVTTIGYGNLAPSTEAGQVFCVFYALLGIP 134
Query: 125 LCLTWISALGKFFGGRAKRLGQFLTKRGVSLRKAQITCTVIFIVWGVLVHLVIPPFVFMV 184
L + +++ LG + ++ R + Q+ +F+ G LV L+ PP VF
Sbjct: 135 LNVIFLNHLGTGLRAHLAAIERW-EDRPRRSQVLQVLGLALFLTLGTLVILIFPPMVFSH 193
Query: 185 TEGWNYIEGLYYSFITISTIGFGDFVAG 212
EGW++ EG Y++FIT+STIGFGD+V G
Sbjct: 194 VEGWSFSEGFYFAFITLSTIGFGDYVVG 221
>gi|14589851 potassium channel, subfamily K, member 2 isoform b
[Homo sapiens]
Length = 411
Score = 162 bits (410), Expect = 7e-40
Identities = 83/243 (34%), Positives = 138/243 (56%), Gaps = 11/243 (4%)
Query: 12 IIFYLAIGAAIFEVLEEPHWKEAKKNYYTQKLHLLKEFPCLGQEGLDKILEVVSDAAGQG 71
++ YL IGA +F+ LE+PH + QK + + C+ LD++++ + A G
Sbjct: 54 VVLYLIIGATVFKALEQPHEISQRTTIVIQKQTFISQHSCVNSTELDELIQQIVAAINAG 113
Query: 72 VAITGNQT--FNNWNWPNAMIFAATVITTIGYGNVAPKTPAGRLFCVFYGLFGVPLCLTW 129
+ GN + ++W+ ++ FA TVITTIG+GN++P+T G++FC+ Y L G+PL
Sbjct: 114 IIPLGNTSNQISHWDLGSSFFFAGTVITTIGFGNISPRTEGGKIFCIIYALLGIPLFGFL 173
Query: 130 ISA----LGKFFGGRAKRLGQFLTKRGVSLRKAQITCTVIFIVWGVLVHLVIPPFVFMVT 185
++ LG FG ++ K VS K +I T+IFI++G ++ + +P +F
Sbjct: 174 LAGVGDQLGTIFGKGIAKVEDTFIKWNVSQTKIRIISTIIFILFGCVLFVALPAIIFKHI 233
Query: 186 EGWNYIEGLYYSFITISTIGFGDFVAGVNPSANYHALYRYFVELWIYLGLAW----LSLF 241
EGW+ ++ +Y+ IT++TIGFGD+VAG Y Y+ V WI +GLA+ LS+
Sbjct: 234 EGWSALDAIYFVVITLTTIGFGDYVAG-GSDIEYLDFYKPVVWFWILVGLAYFAAVLSMI 292
Query: 242 VNW 244
+W
Sbjct: 293 GDW 295
>gi|126365795 potassium channel, subfamily K, member 2 isoform c
[Homo sapiens]
Length = 426
Score = 162 bits (410), Expect = 7e-40
Identities = 83/243 (34%), Positives = 138/243 (56%), Gaps = 11/243 (4%)
Query: 12 IIFYLAIGAAIFEVLEEPHWKEAKKNYYTQKLHLLKEFPCLGQEGLDKILEVVSDAAGQG 71
++ YL IGA +F+ LE+PH + QK + + C+ LD++++ + A G
Sbjct: 69 VVLYLIIGATVFKALEQPHEISQRTTIVIQKQTFISQHSCVNSTELDELIQQIVAAINAG 128
Query: 72 VAITGNQT--FNNWNWPNAMIFAATVITTIGYGNVAPKTPAGRLFCVFYGLFGVPLCLTW 129
+ GN + ++W+ ++ FA TVITTIG+GN++P+T G++FC+ Y L G+PL
Sbjct: 129 IIPLGNTSNQISHWDLGSSFFFAGTVITTIGFGNISPRTEGGKIFCIIYALLGIPLFGFL 188
Query: 130 ISA----LGKFFGGRAKRLGQFLTKRGVSLRKAQITCTVIFIVWGVLVHLVIPPFVFMVT 185
++ LG FG ++ K VS K +I T+IFI++G ++ + +P +F
Sbjct: 189 LAGVGDQLGTIFGKGIAKVEDTFIKWNVSQTKIRIISTIIFILFGCVLFVALPAIIFKHI 248
Query: 186 EGWNYIEGLYYSFITISTIGFGDFVAGVNPSANYHALYRYFVELWIYLGLAW----LSLF 241
EGW+ ++ +Y+ IT++TIGFGD+VAG Y Y+ V WI +GLA+ LS+
Sbjct: 249 EGWSALDAIYFVVITLTTIGFGDYVAG-GSDIEYLDFYKPVVWFWILVGLAYFAAVLSMI 307
Query: 242 VNW 244
+W
Sbjct: 308 GDW 310
>gi|62912487 potassium channel, subfamily K, member 2 isoform a
[Homo sapiens]
Length = 422
Score = 162 bits (410), Expect = 7e-40
Identities = 83/243 (34%), Positives = 138/243 (56%), Gaps = 11/243 (4%)
Query: 12 IIFYLAIGAAIFEVLEEPHWKEAKKNYYTQKLHLLKEFPCLGQEGLDKILEVVSDAAGQG 71
++ YL IGA +F+ LE+PH + QK + + C+ LD++++ + A G
Sbjct: 65 VVLYLIIGATVFKALEQPHEISQRTTIVIQKQTFISQHSCVNSTELDELIQQIVAAINAG 124
Query: 72 VAITGNQT--FNNWNWPNAMIFAATVITTIGYGNVAPKTPAGRLFCVFYGLFGVPLCLTW 129
+ GN + ++W+ ++ FA TVITTIG+GN++P+T G++FC+ Y L G+PL
Sbjct: 125 IIPLGNTSNQISHWDLGSSFFFAGTVITTIGFGNISPRTEGGKIFCIIYALLGIPLFGFL 184
Query: 130 ISA----LGKFFGGRAKRLGQFLTKRGVSLRKAQITCTVIFIVWGVLVHLVIPPFVFMVT 185
++ LG FG ++ K VS K +I T+IFI++G ++ + +P +F
Sbjct: 185 LAGVGDQLGTIFGKGIAKVEDTFIKWNVSQTKIRIISTIIFILFGCVLFVALPAIIFKHI 244
Query: 186 EGWNYIEGLYYSFITISTIGFGDFVAGVNPSANYHALYRYFVELWIYLGLAW----LSLF 241
EGW+ ++ +Y+ IT++TIGFGD+VAG Y Y+ V WI +GLA+ LS+
Sbjct: 245 EGWSALDAIYFVVITLTTIGFGDYVAG-GSDIEYLDFYKPVVWFWILVGLAYFAAVLSMI 303
Query: 242 VNW 244
+W
Sbjct: 304 GDW 306
>gi|15718767 TRAAK [Homo sapiens]
Length = 393
Score = 162 bits (409), Expect = 9e-40
Identities = 87/249 (34%), Positives = 140/249 (56%), Gaps = 13/249 (5%)
Query: 8 LTSAIIFYLAIGAAIFEVLEEPHWKEAKKNYYTQKLHLLKEFPCLGQEGLDKILEVVSDA 67
L + ++ YL GA +F LE+PH ++A++ + L+ PC+ + L +++ V+DA
Sbjct: 9 LLALVLLYLVSGALVFRALEQPHEQQAQRELGEVREKFLRAHPCVSDQELGLLIKEVADA 68
Query: 68 AGQGVAITGNQTFNN----WNWPNAMIFAATVITTIGYGNVAPKTPAGRLFCVFYGLFGV 123
G G N T N+ W+ +A F+ T+ITTIGYGNVA +T AGRLFC+FY L G+
Sbjct: 69 LGGGADPETNSTSNSSHSAWDLGSAFFFSGTIITTIGYGNVALRTDAGRLFCIFYALVGI 128
Query: 124 PLCLTWISALGKFFGGRAK----RLGQFLTKRGVSLRKAQITCTVIFIVWGVLVHLVIPP 179
PL ++ +G G + + K V ++ ++F++ G L+ ++ P
Sbjct: 129 PLFGILLAGVGDRLGSSLRHGIGHIEAIFLKWHVPPELVRVLSAMLFLLIGCLLFVLTPT 188
Query: 180 FVFMVTEGWNYIEGLYYSFITISTIGFGDFVAGVNPSANYHALYRYFVELWIYLGLAW-- 237
FVF E W+ +E +Y+ +T++T+GFGD+VAG +P + A Y+ V WI LGLA+
Sbjct: 189 FVFCYMEDWSKLEAIYFVIVTLTTVGFGDYVAGADPRQDSPA-YQPLVWFWILLGLAYFA 247
Query: 238 --LSLFVNW 244
L+ NW
Sbjct: 248 SVLTTIGNW 256
>gi|205361107 potassium channel, subfamily K, member 17 isoform 2
[Homo sapiens]
Length = 271
Score = 141 bits (356), Expect = 1e-33
Identities = 74/205 (36%), Positives = 113/205 (55%), Gaps = 1/205 (0%)
Query: 7 LLTSAIIFYLAIGAAIFEVLEEPHWKEAKKNYYTQKLHLLKEFPCLGQEGLDKILEVVSD 66
LL A + YLA+G +F LE +++ +++ K LL+ F CL + LD ++ V
Sbjct: 24 LLLLAYLAYLALGTGVFWTLEGRAAQDSSRSFQRDKWELLQNFTCLDRPALDSLIRDVVQ 83
Query: 67 AAGQGVAITGNQT-FNNWNWPNAMIFAATVITTIGYGNVAPKTPAGRLFCVFYGLFGVPL 125
A G ++ N T W + F+ + ITTIGYGN++P T A RLFC+F+ L G+PL
Sbjct: 84 AYKNGASLLSNTTSMGRWELVGSFFFSVSTITTIGYGNLSPNTMAARLFCIFFALVGIPL 143
Query: 126 CLTWISALGKFFGGRAKRLGQFLTKRGVSLRKAQITCTVIFIVWGVLVHLVIPPFVFMVT 185
L ++ LG L KA+ ++ G+L+ L++PP +F
Sbjct: 144 NLVVLNRLGHLMQQGVNHWASRLGGTWQDPDKARWLAGSGALLSGLLLFLLLPPLLFSHM 203
Query: 186 EGWNYIEGLYYSFITISTIGFGDFV 210
EGW+Y EG Y++FIT+ST+GFGD+V
Sbjct: 204 EGWSYTEGFYFAFITLSTVGFGDYV 228
>gi|4504847 potassium channel, subfamily K, member 1 [Homo sapiens]
Length = 336
Score = 133 bits (335), Expect = 3e-31
Identities = 86/279 (30%), Positives = 149/279 (53%), Gaps = 26/279 (9%)
Query: 8 LTSAIIFYLAIGAAIFEVLEEPHWKEAKKNYYTQKLHLLKEFPCLGQEGLDKILEVVSDA 67
L + YL GA +F +E P+ ++ K L+E CL ++ L++ L V +A
Sbjct: 26 LVLGYLLYLVFGAVVFSSVELPYEDLLRQELRKLKRRFLEEHECLSEQQLEQFLGRVLEA 85
Query: 68 AGQGVAITGNQTFN-NWNWPNAMIFAATVITTIGYGNVAPKTPAGRLFCVFYGLFGVPLC 126
+ GV++ N + N NW++ +A+ FA+TV++T GYG+ P + G+ FC+ Y + G+P
Sbjct: 86 SNYGVSVLSNASGNWNWDFTSALFFASTVLSTTGYGHTVPLSDGGKAFCIIYSVIGIPFT 145
Query: 127 LTWISALGKFFGGRAKRLGQFLTKRGVSLRKAQ--ITCTVIFIVWGVLVHLV-------I 177
L +++A+ +R+ +T+R V + + V+ IV VL+ V I
Sbjct: 146 LLFLTAV-------VQRITVHVTRRPVLYFHIRWGFSKQVVAIVHAVLLGFVTVSCFFFI 198
Query: 178 PPFVFMVTE-GWNYIEGLYYSFITISTIGFGDFVAGVNPSANYHALYRYFVELWIYLGLA 236
P VF V E WN++E Y+ FI++STIG GD+V G + + LY+ + ++ LGL
Sbjct: 199 PAAVFSVLEDDWNFLESFYFCFISLSTIGLGDYVPGEGYNQKFRELYKIGITCYLLLGL- 257
Query: 237 WLSLFVNWKVSMFVEVHKAIKKRRRR---RKESFESSPH 272
+++ V + F E+H+ +KK R+ +K+ E H
Sbjct: 258 -IAMLV--VLETFCELHE-LKKFRKMFYVKKDKDEDQVH 292
>gi|4758624 potassium channel, subfamily K, member 6 [Homo sapiens]
Length = 313
Score = 127 bits (320), Expect = 2e-29
Identities = 82/256 (32%), Positives = 128/256 (50%), Gaps = 26/256 (10%)
Query: 4 RGPLLTSAIIFY---LAIGAAIFEVLEEPHWKEAKKNYYTQKLHLLKEFPCLGQEGLDKI 60
RG LL A+ Y L +GA + LE PH + T + LL+ PC+ LD
Sbjct: 3 RGALLAGALAAYAAYLVLGALLVARLEGPHEARLRAELETLRAQLLQRSPCVAAPALDAF 62
Query: 61 LEVVSDAAGQGVAITGNQTFNN------WNWPNAMIFAATVITTIGYGNVAPKTPAGRLF 114
+E V A G + N + + W++ +A+ FA+T+ITT+GYG P T AG+ F
Sbjct: 63 VERVLAAGRLGRVVLANASGSANASDPAWDFASALFFASTLITTVGYGYTTPLTDAGKAF 122
Query: 115 CVFYGLFGVPLCLTWISALGKFFGGRAKRLGQFLT---------KRGVSLRKAQITCTVI 165
+ + L GVP + ++A A+RL LT + G R+A V
Sbjct: 123 SIAFALLGVPTTMLLLTA-------SAQRLSLLLTHVPLSWLSMRWGWDPRRAACWHLVA 175
Query: 166 FIVWGVLVHLVIPPFVFM-VTEGWNYIEGLYYSFITISTIGFGDFVAGVNPSANYHALYR 224
+ V V ++P +F + E W++++ Y+ FI++STIG GD+V G P Y ALY+
Sbjct: 176 LLGVVVTVCFLVPAVIFAHLEEAWSFLDAFYFCFISLSTIGLGDYVPGEAPGQPYRALYK 235
Query: 225 YFVELWIYLGLAWLSL 240
V ++++LGL + L
Sbjct: 236 VLVTVYLFLGLVAMVL 251
>gi|4504849 potassium channel, subfamily K, member 3 [Homo sapiens]
Length = 394
Score = 120 bits (300), Expect = 4e-27
Identities = 82/252 (32%), Positives = 131/252 (51%), Gaps = 20/252 (7%)
Query: 15 YLAIGAAIFEVLE-EPHWKEAKKNYYTQKLHLLKEFPCLGQEGLDKILEVVSDAAGQGVA 73
YL +GAA+F+ LE EP E ++ Q+ L+ L Q G +++ VV +
Sbjct: 18 YLLVGAAVFDALESEPELIERQRLELRQQE--LRARYNLSQGGYEELERVV-------LR 68
Query: 74 ITGNQTFNNWNWPNAMIFAATVITTIGYGNVAPKTPAGRLFCVFYGLFGVPLCLTWISAL 133
+ ++ W + + FA TVITTIGYG+ AP T G++FC+FY L G+PL L +L
Sbjct: 69 LKPHKAGVQWRFAGSFYFAITVITTIGYGHAAPSTDGGKVFCMFYALLGIPLTLVMFQSL 128
Query: 134 GKFFGGRAKRLGQFL---TKRGVSLRKAQITCTVIFIV--WGVLVHLVIPPFVFMVTEGW 188
G+ R L ++L K+G+ +R+A ++ + ++ + + L I F E W
Sbjct: 129 GE----RINTLVRYLLHRAKKGLGMRRADVSMANMVLIGFFSCISTLCIGAAAFSHYEHW 184
Query: 189 NYIEGLYYSFITISTIGFGDFVAGVNPSA-NYHALYRYFVELWIYLGLAWLSLFVNWKVS 247
+ + YY FIT++TIGFGD+VA A Y F ++I GL + F+N V
Sbjct: 185 TFFQAYYYCFITLTTIGFGDYVALQKDQALQTQPQYVAFSFVYILTGLTVIGAFLNLVVL 244
Query: 248 MFVEVHKAIKKR 259
F+ ++ +KR
Sbjct: 245 RFMTMNAEDEKR 256
>gi|11641275 potassium family, subfamily K, member 15 [Homo sapiens]
Length = 330
Score = 118 bits (295), Expect = 1e-26
Identities = 86/251 (34%), Positives = 124/251 (49%), Gaps = 22/251 (8%)
Query: 8 LTSAIIFYLAIGAAIFEVLEEPHWKEAKKNYYTQKLHLLKE---FPCLGQEGLDKI-LEV 63
L + YL +GAA+F+ LE + ++ QK L+ F L+++ L+
Sbjct: 11 LVLCTLCYLLVGAAVFDALESEA-ESGRQRLLVQKRGALRRKFGFSAEDYRELERLALQA 69
Query: 64 VSDAAGQGVAITGNQTFNNWNWPNAMIFAATVITTIGYGNVAPKTPAGRLFCVFYGLFGV 123
AG+ W +P + FA TVITTIGYG+ AP T +G++FC+FY L G+
Sbjct: 70 EPHRAGR-----------QWKFPGSFYFAITVITTIGYGHAAPGTDSGKVFCMFYALLGI 118
Query: 124 PLCLTWISALGKFFGGRAKRLGQFLTKRGVSLRKAQITCTVIFIVWGVL---VHLVIPPF 180
PL L +LG+ +RL K + LR ++ T +V G+L L +
Sbjct: 119 PLTLVTFQSLGERLNAVVRRL-LLAAKCCLGLRWTCVS-TENLVVAGLLACAATLALGAV 176
Query: 181 VFMVTEGWNYIEGLYYSFITISTIGFGDFVAGVNPSANYHAL-YRYFVELWIYLGLAWLS 239
F EGW + YY FIT++TIGFGDFVA + A L Y F L+I LGL +
Sbjct: 177 AFSHFEGWTFFHAYYYCFITLTTIGFGDFVALQSGEALQRKLPYVAFSFLYILLGLTVIG 236
Query: 240 LFVNWKVSMFV 250
F+N V F+
Sbjct: 237 AFLNLVVLRFL 247
>gi|7706135 potassium channel, subfamily K, member 9 [Homo sapiens]
Length = 374
Score = 116 bits (291), Expect = 4e-26
Identities = 78/265 (29%), Positives = 125/265 (47%), Gaps = 18/265 (6%)
Query: 15 YLAIGAAIFEVLEEPHWKEAKKNYYTQKLHLLKEFPCLGQEGLDKILEVV-SDAAGQGVA 73
YL +GAA+F+ LE H ++ +++ + ++ ++ L ++ S+ GV
Sbjct: 18 YLLVGAAVFDALESDHEMREEEKLKAEEIRIKGKYNISSEDYRQLELVILQSEPHRAGV- 76
Query: 74 ITGNQTFNNWNWPNAMIFAATVITTIGYGNVAPKTPAGRLFCVFYGLFGVPLCLTWISAL 133
W + + FA TVITTIGYG+ AP T AG+ FC+FY + G+PL L +L
Sbjct: 77 --------QWKFAGSFYFAITVITTIGYGHAAPGTDAGKAFCMFYAVLGIPLTLVMFQSL 128
Query: 134 GK----FFGGRAKRLGQFLTKRGVSLRKAQITCTVIFIVWGVLVHLVIPPFVFMVTEGWN 189
G+ F KR+ + R + + F G L I F E W+
Sbjct: 129 GERMNTFVRYLLKRIKKCCGMRNTDVSMENMVTVGFFSCMGT---LCIGAAAFSQCEEWS 185
Query: 190 YIEGLYYSFITISTIGFGDFVAGVNPSA-NYHALYRYFVELWIYLGLAWLSLFVNWKVSM 248
+ YY FIT++TIGFGD+VA A LY F ++I +GL + F+N V
Sbjct: 186 FFHAYYYCFITLTTIGFGDYVALQTKGALQKKPLYVAFSFMYILVGLTVIGAFLNLVVLR 245
Query: 249 FVEVHKAIKKRRRRRKESFESSPHS 273
F+ ++ ++R + S + +S
Sbjct: 246 FLTMNSEDERRDAEERASLAGNRNS 270
>gi|16306555 potassium channel, subfamily K, member 13 [Homo
sapiens]
Length = 408
Score = 95.9 bits (237), Expect = 8e-20
Identities = 71/258 (27%), Positives = 119/258 (46%), Gaps = 26/258 (10%)
Query: 7 LLTSAIIFYLAIGAAIFEVLEEPHWKEAKKNYYTQKLHLLKEFPCLGQEGLDKILEVVSD 66
LL + I+ YL GAA+F LE H ++AK+ + ++L L ++ L L +
Sbjct: 22 LLAALIVLYLLGGAAVFSALELAHERQAKQRW-EERLANFSRGHNLSRDELRGFLRHYEE 80
Query: 67 AAGQGVAITGNQTFNNWNWPNAMIFAATVITTIGYGNVAPKTPAGRLFCVFYGLFG---- 122
A G+ + + W++ A F TV++TIG+G P T G++F +FYGL G
Sbjct: 81 ATRAGIRVDNVRP--RWDFTGAFYFVGTVVSTIGFGMTTPATVGGKIFLIFYGLVGCSST 138
Query: 123 -------VPLCLTWISALGKFFGGRAKRLGQFLTKRGV---------SLR--KAQITCTV 164
+ +T I+ + K R R L + + SL K + +
Sbjct: 139 ILFFNLFLERLITIIAYIMKSCHQRQLRRRGALPQESLKDAGQCEVDSLAGWKPSVYYVM 198
Query: 165 IFIVWGVLVHLVIPPFVFMVTEGWNYIEGLYYSFITISTIGFGDFVAGVNPSANYHALYR 224
+ + ++ ++ EGW+Y + LY+ F+ STIGFGD V+ N LYR
Sbjct: 199 LILCTASILISCCASAMYTPIEGWSYFDSLYFCFVAFSTIGFGDLVSSQNAHYESQGLYR 258
Query: 225 YFVELWIYLGLAWL-SLF 241
+ ++I +G+ + SLF
Sbjct: 259 FANFVFILMGVCCIYSLF 276
>gi|11545761 potassium channel, subfamily K, member 12 [Homo
sapiens]
Length = 430
Score = 92.4 bits (228), Expect = 8e-19
Identities = 80/262 (30%), Positives = 119/262 (45%), Gaps = 34/262 (12%)
Query: 7 LLTSAIIFYLAIGAAIFEVLEEPHWKEAKKNYYTQKLHLLKEFPC---LGQEGLDKILEV 63
LL + I YL GA +F LE P EA+ + L+ F + + L L
Sbjct: 41 LLAALIGLYLVAGATVFSALESPGEAEARARWGAT----LRNFSAAHGVAEPELRAFLRH 96
Query: 64 VSDAAGQGVAITGNQTFNNWNWPNAMIFAATVITTIGYGNVAPKTPAGRLFCVFYGLFGV 123
A GV + W++P A F TV++TIG+G P T G+ F + YGLFG
Sbjct: 97 YEAALAAGVRADALRP--RWDFPGAFYFVGTVVSTIGFGMTTPATVGGKAFLIAYGLFGC 154
Query: 124 P-------LCLTWISALGKFFGGRAKRLGQF--------LTKRGVSLRKA------QITC 162
L L I +L F RA R Q +RG +L +A + +
Sbjct: 155 AGTILFFNLFLERIISLLAFI-MRACRERQLRRSGLLPATFRRGSALSEADSLAGWKPSV 213
Query: 163 TVIFIVWGVLVHLV--IPPFVFMVTEGWNYIEGLYYSFITISTIGFGDFVAGVNPSANYH 220
+ ++ G+ L+ ++ EGW+Y++ LY+ F+T STIGFGD V+ + +
Sbjct: 214 YHVLLILGLFAVLLSCCASAMYTSVEGWDYVDSLYFCFVTFSTIGFGDLVSSQHAAYRNQ 273
Query: 221 ALYRYFVELWIYLGLAWL-SLF 241
LYR L+I LG+ + SLF
Sbjct: 274 GLYRLGNFLFILLGVCCIYSLF 295
>gi|5031821 potassium channel, subfamily K, member 7 isoform C [Homo
sapiens]
Length = 257
Score = 80.9 bits (198), Expect = 3e-15
Identities = 56/210 (26%), Positives = 99/210 (47%), Gaps = 4/210 (1%)
Query: 7 LLTSAIIFYLAIGAAIFEVLEEPHWKEAKKNYYTQKLHLLKEF-PCLGQEGLDKILEVVS 65
LL A + L +GA +F+ LE P + + E CL L+++L
Sbjct: 12 LLVVAHLLALGLGAVVFQALEGPPACRLQAELRAELAAFQAEHRACLPPGALEELLGTAL 71
Query: 66 DAAGQGVAITGNQTFNN-WNWPNAMIFAATVITTIGYGNVAPKTPAGRLFCVFYGLFGVP 124
GV+ GN + W+ P+A++FAA+++TT GYG++AP +P G+ FC+ Y G+P
Sbjct: 72 ATQAHGVSTLGNSSEGRTWDLPSALLFAASILTTTGYGHMAPLSPGGKAFCMVYAALGLP 131
Query: 125 LCLTWISALGKFFGGRAKRLGQFLTKR-GVSLRKAQITCTVIFIVWGVLVHLVIPPFVFM 183
L ++ L R ++ +S +A + V + +++P V
Sbjct: 132 ASLALVATLRHCLLPVLSRPRAWVAVHWQLSPARAALLQAVALGLLVASSFVLLPALVLW 191
Query: 184 VTEG-WNYIEGLYYSFITISTIGFGDFVAG 212
+G + + +Y+ F ++STIG D + G
Sbjct: 192 GLQGDCSLLGAVYFCFSSLSTIGLEDLLPG 221
>gi|16118231 potassium channel, subfamily K, member 7 isoform A
[Homo sapiens]
Length = 307
Score = 80.9 bits (198), Expect = 3e-15
Identities = 56/210 (26%), Positives = 99/210 (47%), Gaps = 4/210 (1%)
Query: 7 LLTSAIIFYLAIGAAIFEVLEEPHWKEAKKNYYTQKLHLLKEF-PCLGQEGLDKILEVVS 65
LL A + L +GA +F+ LE P + + E CL L+++L
Sbjct: 12 LLVVAHLLALGLGAVVFQALEGPPACRLQAELRAELAAFQAEHRACLPPGALEELLGTAL 71
Query: 66 DAAGQGVAITGNQTFNN-WNWPNAMIFAATVITTIGYGNVAPKTPAGRLFCVFYGLFGVP 124
GV+ GN + W+ P+A++FAA+++TT GYG++AP +P G+ FC+ Y G+P
Sbjct: 72 ATQAHGVSTLGNSSEGRTWDLPSALLFAASILTTTGYGHMAPLSPGGKAFCMVYAALGLP 131
Query: 125 LCLTWISALGKFFGGRAKRLGQFLTKR-GVSLRKAQITCTVIFIVWGVLVHLVIPPFVFM 183
L ++ L R ++ +S +A + V + +++P V
Sbjct: 132 ASLALVATLRHCLLPVLSRPRAWVAVHWQLSPARAALLQAVALGLLVASSFVLLPALVLW 191
Query: 184 VTEG-WNYIEGLYYSFITISTIGFGDFVAG 212
+G + + +Y+ F ++STIG D + G
Sbjct: 192 GLQGDCSLLGAVYFCFSSLSTIGLEDLLPG 221
>gi|16118235 potassium channel, subfamily K, member 7 isoform B
[Homo sapiens]
Length = 252
Score = 80.9 bits (198), Expect = 3e-15
Identities = 56/210 (26%), Positives = 99/210 (47%), Gaps = 4/210 (1%)
Query: 7 LLTSAIIFYLAIGAAIFEVLEEPHWKEAKKNYYTQKLHLLKEF-PCLGQEGLDKILEVVS 65
LL A + L +GA +F+ LE P + + E CL L+++L
Sbjct: 12 LLVVAHLLALGLGAVVFQALEGPPACRLQAELRAELAAFQAEHRACLPPGALEELLGTAL 71
Query: 66 DAAGQGVAITGNQTFNN-WNWPNAMIFAATVITTIGYGNVAPKTPAGRLFCVFYGLFGVP 124
GV+ GN + W+ P+A++FAA+++TT GYG++AP +P G+ FC+ Y G+P
Sbjct: 72 ATQAHGVSTLGNSSEGRTWDLPSALLFAASILTTTGYGHMAPLSPGGKAFCMVYAALGLP 131
Query: 125 LCLTWISALGKFFGGRAKRLGQFLTKR-GVSLRKAQITCTVIFIVWGVLVHLVIPPFVFM 183
L ++ L R ++ +S +A + V + +++P V
Sbjct: 132 ASLALVATLRHCLLPVLSRPRAWVAVHWQLSPARAALLQAVALGLLVASSFVLLPALVLW 191
Query: 184 VTEG-WNYIEGLYYSFITISTIGFGDFVAG 212
+G + + +Y+ F ++STIG D + G
Sbjct: 192 GLQGDCSLLGAVYFCFSSLSTIGLEDLLPG 221
>gi|16118233 potassium channel, subfamily K, member 7 isoform B
[Homo sapiens]
Length = 252
Score = 80.9 bits (198), Expect = 3e-15
Identities = 56/210 (26%), Positives = 99/210 (47%), Gaps = 4/210 (1%)
Query: 7 LLTSAIIFYLAIGAAIFEVLEEPHWKEAKKNYYTQKLHLLKEF-PCLGQEGLDKILEVVS 65
LL A + L +GA +F+ LE P + + E CL L+++L
Sbjct: 12 LLVVAHLLALGLGAVVFQALEGPPACRLQAELRAELAAFQAEHRACLPPGALEELLGTAL 71
Query: 66 DAAGQGVAITGNQTFNN-WNWPNAMIFAATVITTIGYGNVAPKTPAGRLFCVFYGLFGVP 124
GV+ GN + W+ P+A++FAA+++TT GYG++AP +P G+ FC+ Y G+P
Sbjct: 72 ATQAHGVSTLGNSSEGRTWDLPSALLFAASILTTTGYGHMAPLSPGGKAFCMVYAALGLP 131
Query: 125 LCLTWISALGKFFGGRAKRLGQFLTKR-GVSLRKAQITCTVIFIVWGVLVHLVIPPFVFM 183
L ++ L R ++ +S +A + V + +++P V
Sbjct: 132 ASLALVATLRHCLLPVLSRPRAWVAVHWQLSPARAALLQAVALGLLVASSFVLLPALVLW 191
Query: 184 VTEG-WNYIEGLYYSFITISTIGFGDFVAG 212
+G + + +Y+ F ++STIG D + G
Sbjct: 192 GLQGDCSLLGAVYFCFSSLSTIGLEDLLPG 221
>gi|32469495 potassium channel, subfamily K, member 18 [Homo
sapiens]
Length = 384
Score = 51.6 bits (122), Expect = 2e-06
Identities = 33/126 (26%), Positives = 60/126 (47%), Gaps = 6/126 (4%)
Query: 12 IIFYLAIGAAIFEVLEEPHWKEAKKNYYTQKLHLLKEFPCLGQEGLDKILEVVSDAAGQG 71
++ Y +GA +F +E+ A + +K L+E C + ++E
Sbjct: 30 LVTYALVGAVVFSAIEDGQVLVAADDGEFEKF--LEEL-CRILNCSETVVEDRKQDLQGH 86
Query: 72 VAITGNQTFN---NWNWPNAMIFAATVITTIGYGNVAPKTPAGRLFCVFYGLFGVPLCLT 128
+ Q FN +W++ +++ F TV +T+GYG + P T G+ C+ Y LFG+PL
Sbjct: 87 LQKVKPQWFNRTTHWSFLSSLFFCCTVFSTVGYGYIYPVTRLGKYLCMLYALFGIPLMFL 146
Query: 129 WISALG 134
++ G
Sbjct: 147 VLTDTG 152
Score = 31.6 bits (70), Expect = 1.8
Identities = 21/109 (19%), Positives = 48/109 (44%), Gaps = 8/109 (7%)
Query: 148 LTKRGVSLRKAQITCTVIFIVWGVLVHLVIPPFVFMVTEGWNYIEGLYYSFITISTIGFG 207
L + G + + I +I ++ + F T+ ++ Y+ F+T++TIGFG
Sbjct: 269 LDEVGQQVERLDIPLPIIALIVFAYISCAAAILPFWETQ-LDFENAFYFCFVTLTTIGFG 327
Query: 208 DFVAGVNPSANYHALYRYFVELWIYLGLAWLSLFVNWKVSMFVEVHKAI 256
D V H + F ++I +G+ + + + ++++K +
Sbjct: 328 DTVL-------EHPNFFLFFSIYIIVGMEIVFIAFKLVQNRLIDIYKNV 369
>gi|238624132 large conductance calcium-activated potassium channel
subfamily M alpha member 1 isoform d [Homo sapiens]
Length = 1219
Score = 45.1 bits (105), Expect = 2e-04
Identities = 27/86 (31%), Positives = 42/86 (48%), Gaps = 6/86 (6%)
Query: 77 NQTFNNWNWPNAMIFAATVITTIGYGNVAPKTPAGRLFCVFYGLFGVPLCLTWISALGKF 136
NQ W + ++T+GYG+V KT GRLF VF+ L G+ + +++ + +
Sbjct: 334 NQALTYWE---CVYLLMVTMSTVGYGDVYAKTTLGRLFMVFFILGGLAMFASYVPEIIEL 390
Query: 137 FGGRAKRLGQFLTKRGVSLRKAQITC 162
G R K G + VS RK + C
Sbjct: 391 IGNRKKYGGSY---SAVSGRKHIVVC 413
Score = 32.0 bits (71), Expect = 1.3
Identities = 31/123 (25%), Positives = 50/123 (40%), Gaps = 18/123 (14%)
Query: 182 FMVTEGWNYIEGLYYSFITISTIGFGDFVAGVNPSANYHALYRYFVELWIYLGLAWLSLF 241
F + Y E +Y +T+ST+G+GD A L R F+ +I GLA + +
Sbjct: 331 FQNNQALTYWECVYLLMVTMSTVGYGDVYAKT-------TLGRLFMVFFILGGLAMFASY 383
Query: 242 VNWKVSMFVEVHKAIKKRRRRRKESFESSPHSRKALQVKGSTASKDVNIF--SFLSKKEE 299
V + + R++ S+ RK + V G + V+ F FL K +
Sbjct: 384 VPEIIELI---------GNRKKYGGSYSAVSGRKHIVVCGHITLESVSNFLKDFLHKDRD 434
Query: 300 TYN 302
N
Sbjct: 435 DVN 437
>gi|238624130 large conductance calcium-activated potassium channel
subfamily M alpha member 1 isoform c [Homo sapiens]
Length = 1236
Score = 45.1 bits (105), Expect = 2e-04
Identities = 27/86 (31%), Positives = 42/86 (48%), Gaps = 6/86 (6%)
Query: 77 NQTFNNWNWPNAMIFAATVITTIGYGNVAPKTPAGRLFCVFYGLFGVPLCLTWISALGKF 136
NQ W + ++T+GYG+V KT GRLF VF+ L G+ + +++ + +
Sbjct: 334 NQALTYWE---CVYLLMVTMSTVGYGDVYAKTTLGRLFMVFFILGGLAMFASYVPEIIEL 390
Query: 137 FGGRAKRLGQFLTKRGVSLRKAQITC 162
G R K G + VS RK + C
Sbjct: 391 IGNRKKYGGSY---SAVSGRKHIVVC 413
Score = 32.0 bits (71), Expect = 1.3
Identities = 31/123 (25%), Positives = 50/123 (40%), Gaps = 18/123 (14%)
Query: 182 FMVTEGWNYIEGLYYSFITISTIGFGDFVAGVNPSANYHALYRYFVELWIYLGLAWLSLF 241
F + Y E +Y +T+ST+G+GD A L R F+ +I GLA + +
Sbjct: 331 FQNNQALTYWECVYLLMVTMSTVGYGDVYAKT-------TLGRLFMVFFILGGLAMFASY 383
Query: 242 VNWKVSMFVEVHKAIKKRRRRRKESFESSPHSRKALQVKGSTASKDVNIF--SFLSKKEE 299
V + + R++ S+ RK + V G + V+ F FL K +
Sbjct: 384 VPEIIELI---------GNRKKYGGSYSAVSGRKHIVVCGHITLESVSNFLKDFLHKDRD 434
Query: 300 TYN 302
N
Sbjct: 435 DVN 437
>gi|62388890 large conductance calcium-activated potassium channel
subfamily M alpha member 1 isoform a [Homo sapiens]
Length = 1182
Score = 45.1 bits (105), Expect = 2e-04
Identities = 27/86 (31%), Positives = 42/86 (48%), Gaps = 6/86 (6%)
Query: 77 NQTFNNWNWPNAMIFAATVITTIGYGNVAPKTPAGRLFCVFYGLFGVPLCLTWISALGKF 136
NQ W + ++T+GYG+V KT GRLF VF+ L G+ + +++ + +
Sbjct: 334 NQALTYWE---CVYLLMVTMSTVGYGDVYAKTTLGRLFMVFFILGGLAMFASYVPEIIEL 390
Query: 137 FGGRAKRLGQFLTKRGVSLRKAQITC 162
G R K G + VS RK + C
Sbjct: 391 IGNRKKYGGSY---SAVSGRKHIVVC 413
Score = 32.0 bits (71), Expect = 1.3
Identities = 31/123 (25%), Positives = 50/123 (40%), Gaps = 18/123 (14%)
Query: 182 FMVTEGWNYIEGLYYSFITISTIGFGDFVAGVNPSANYHALYRYFVELWIYLGLAWLSLF 241
F + Y E +Y +T+ST+G+GD A L R F+ +I GLA + +
Sbjct: 331 FQNNQALTYWECVYLLMVTMSTVGYGDVYAKT-------TLGRLFMVFFILGGLAMFASY 383
Query: 242 VNWKVSMFVEVHKAIKKRRRRRKESFESSPHSRKALQVKGSTASKDVNIF--SFLSKKEE 299
V + + R++ S+ RK + V G + V+ F FL K +
Sbjct: 384 VPEIIELI---------GNRKKYGGSYSAVSGRKHIVVCGHITLESVSNFLKDFLHKDRD 434
Query: 300 TYN 302
N
Sbjct: 435 DVN 437
>gi|26638650 large conductance calcium-activated potassium channel
subfamily M alpha member 1 isoform b [Homo sapiens]
Length = 1178
Score = 45.1 bits (105), Expect = 2e-04
Identities = 27/86 (31%), Positives = 42/86 (48%), Gaps = 6/86 (6%)
Query: 77 NQTFNNWNWPNAMIFAATVITTIGYGNVAPKTPAGRLFCVFYGLFGVPLCLTWISALGKF 136
NQ W + ++T+GYG+V KT GRLF VF+ L G+ + +++ + +
Sbjct: 334 NQALTYWE---CVYLLMVTMSTVGYGDVYAKTTLGRLFMVFFILGGLAMFASYVPEIIEL 390
Query: 137 FGGRAKRLGQFLTKRGVSLRKAQITC 162
G R K G + VS RK + C
Sbjct: 391 IGNRKKYGGSY---SAVSGRKHIVVC 413
Score = 32.0 bits (71), Expect = 1.3
Identities = 31/123 (25%), Positives = 50/123 (40%), Gaps = 18/123 (14%)
Query: 182 FMVTEGWNYIEGLYYSFITISTIGFGDFVAGVNPSANYHALYRYFVELWIYLGLAWLSLF 241
F + Y E +Y +T+ST+G+GD A L R F+ +I GLA + +
Sbjct: 331 FQNNQALTYWECVYLLMVTMSTVGYGDVYAKT-------TLGRLFMVFFILGGLAMFASY 383
Query: 242 VNWKVSMFVEVHKAIKKRRRRRKESFESSPHSRKALQVKGSTASKDVNIF--SFLSKKEE 299
V + + R++ S+ RK + V G + V+ F FL K +
Sbjct: 384 VPEIIELI---------GNRKKYGGSYSAVSGRKHIVVCGHITLESVSNFLKDFLHKDRD 434
Query: 300 TYN 302
N
Sbjct: 435 DVN 437
Database: hs.faa
Posted date: Aug 4, 2009 4:42 PM
Number of letters in database: 18,247,518
Number of sequences in database: 37,866
Lambda K H
0.317 0.135 0.406
Gapped
Lambda K H
0.267 0.0410 0.140
Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Hits to DB: 19,827,127
Number of Sequences: 37866
Number of extensions: 956950
Number of successful extensions: 5469
Number of sequences better than 10.0: 30
Number of HSP's better than 10.0 without gapping: 118
Number of HSP's successfully gapped in prelim test: 71
Number of HSP's that attempted gapping in prelim test: 5029
Number of HSP's gapped (non-prelim): 407
length of query: 499
length of database: 18,247,518
effective HSP length: 106
effective length of query: 393
effective length of database: 14,233,722
effective search space: 5593852746
effective search space used: 5593852746
T: 11
A: 40
X1: 16 ( 7.3 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 41 (21.7 bits)
S2: 64 (29.3 bits)
Search results were obtained with NCBI BLAST and RefSeq entries.
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Guide to the Human Genome
Copyright © 2010 by Stewart Scherer. All rights reserved.