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Search of human proteins with 4504847
BLASTP 2.2.11 [Jun-05-2005]
Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer,
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997),
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs", Nucleic Acids Res. 25:3389-3402.
Query= gi|4504847 potassium channel, subfamily K, member 1 [Homo
sapiens]
(336 letters)
Database: hs.faa
37,866 sequences; 18,247,518 total letters
Searching..................................................done
Score E
Sequences producing significant alignments: (bits) Value
gi|4504847 potassium channel, subfamily K, member 1 [Homo sapiens] 679 0.0
gi|4758624 potassium channel, subfamily K, member 6 [Homo sapiens] 250 1e-66
gi|16118231 potassium channel, subfamily K, member 7 isoform A [... 202 3e-52
gi|5031821 potassium channel, subfamily K, member 7 isoform C [H... 172 4e-43
gi|16118235 potassium channel, subfamily K, member 7 isoform B [... 172 4e-43
gi|16118233 potassium channel, subfamily K, member 7 isoform B [... 172 4e-43
gi|205360983 potassium channel, subfamily K, member 16 isoform 3... 155 4e-38
gi|14149764 potassium channel, subfamily K, member 16 isoform 2 ... 155 4e-38
gi|20143946 potassium channel, subfamily K, member 10 isoform 3 ... 151 7e-37
gi|20143944 potassium channel, subfamily K, member 10 isoform 2 ... 151 7e-37
gi|10863961 potassium channel, subfamily K, member 10 isoform 1 ... 151 7e-37
gi|205360971 potassium channel, subfamily K, member 16 isoform 1... 147 1e-35
gi|205360973 potassium channel, subfamily K, member 16 isoform 4... 146 3e-35
gi|14589851 potassium channel, subfamily K, member 2 isoform b [... 145 5e-35
gi|126365795 potassium channel, subfamily K, member 2 isoform c ... 145 5e-35
gi|62912487 potassium channel, subfamily K, member 2 isoform a [... 145 5e-35
gi|15718767 TRAAK [Homo sapiens] 144 8e-35
gi|4504851 potassium channel, subfamily K, member 5 [Homo sapiens] 133 2e-31
gi|4504849 potassium channel, subfamily K, member 3 [Homo sapiens] 120 2e-27
gi|17025230 potassium channel, subfamily K, member 17 isoform 1 ... 120 2e-27
gi|7706135 potassium channel, subfamily K, member 9 [Homo sapiens] 117 1e-26
gi|11641275 potassium family, subfamily K, member 15 [Homo sapiens] 114 1e-25
gi|16306555 potassium channel, subfamily K, member 13 [Homo sapi... 113 3e-25
gi|205361107 potassium channel, subfamily K, member 17 isoform 2... 108 9e-24
gi|11545761 potassium channel, subfamily K, member 12 [Homo sapi... 105 6e-23
gi|32469495 potassium channel, subfamily K, member 18 [Homo sapi... 60 2e-09
gi|240255505 potassium channel, subfamily T, member 1 [Homo sapi... 41 0.001
gi|41349443 potassium channel, subfamily T, member 2 [Homo sapiens] 38 0.011
gi|4504831 potassium voltage-gated channel, subfamily H, member ... 37 0.019
gi|27437001 potassium voltage-gated channel, subfamily H, member... 37 0.019
>gi|4504847 potassium channel, subfamily K, member 1 [Homo sapiens]
Length = 336
Score = 679 bits (1753), Expect = 0.0
Identities = 336/336 (100%), Positives = 336/336 (100%)
Query: 1 MLQSLAGSSCVRLVERHRSAWCFGFLVLGYLLYLVFGAVVFSSVELPYEDLLRQELRKLK 60
MLQSLAGSSCVRLVERHRSAWCFGFLVLGYLLYLVFGAVVFSSVELPYEDLLRQELRKLK
Sbjct: 1 MLQSLAGSSCVRLVERHRSAWCFGFLVLGYLLYLVFGAVVFSSVELPYEDLLRQELRKLK 60
Query: 61 RRFLEEHECLSEQQLEQFLGRVLEASNYGVSVLSNASGNWNWDFTSALFFASTVLSTTGY 120
RRFLEEHECLSEQQLEQFLGRVLEASNYGVSVLSNASGNWNWDFTSALFFASTVLSTTGY
Sbjct: 61 RRFLEEHECLSEQQLEQFLGRVLEASNYGVSVLSNASGNWNWDFTSALFFASTVLSTTGY 120
Query: 121 GHTVPLSDGGKAFCIIYSVIGIPFTLLFLTAVVQRITVHVTRRPVLYFHIRWGFSKQVVA 180
GHTVPLSDGGKAFCIIYSVIGIPFTLLFLTAVVQRITVHVTRRPVLYFHIRWGFSKQVVA
Sbjct: 121 GHTVPLSDGGKAFCIIYSVIGIPFTLLFLTAVVQRITVHVTRRPVLYFHIRWGFSKQVVA 180
Query: 181 IVHAVLLGFVTVSCFFFIPAAVFSVLEDDWNFLESFYFCFISLSTIGLGDYVPGEGYNQK 240
IVHAVLLGFVTVSCFFFIPAAVFSVLEDDWNFLESFYFCFISLSTIGLGDYVPGEGYNQK
Sbjct: 181 IVHAVLLGFVTVSCFFFIPAAVFSVLEDDWNFLESFYFCFISLSTIGLGDYVPGEGYNQK 240
Query: 241 FRELYKIGITCYLLLGLIAMLVVLETFCELHELKKFRKMFYVKKDKDEDQVHIIEHDQLS 300
FRELYKIGITCYLLLGLIAMLVVLETFCELHELKKFRKMFYVKKDKDEDQVHIIEHDQLS
Sbjct: 241 FRELYKIGITCYLLLGLIAMLVVLETFCELHELKKFRKMFYVKKDKDEDQVHIIEHDQLS 300
Query: 301 FSSITDQAAGMKEDQKQNEPFVATQSSACVDGPANH 336
FSSITDQAAGMKEDQKQNEPFVATQSSACVDGPANH
Sbjct: 301 FSSITDQAAGMKEDQKQNEPFVATQSSACVDGPANH 336
>gi|4758624 potassium channel, subfamily K, member 6 [Homo sapiens]
Length = 313
Score = 250 bits (638), Expect = 1e-66
Identities = 133/297 (44%), Positives = 192/297 (64%), Gaps = 17/297 (5%)
Query: 30 YLLYLVFGAVVFSSVELPYEDLLRQELRKLKRRFLEEHECLSEQQLEQFLGRVLEASNYG 89
Y YLV GA++ + +E P+E LR EL L+ + L+ C++ L+ F+ RVL A G
Sbjct: 14 YAAYLVLGALLVARLEGPHEARLRAELETLRAQLLQRSPCVAAPALDAFVERVLAAGRLG 73
Query: 90 VSVLSNASGNWN-----WDFTSALFFASTVLSTTGYGHTVPLSDGGKAFCIIYSVIGIPF 144
VL+NASG+ N WDF SALFFAST+++T GYG+T PL+D GKAF I ++++G+P
Sbjct: 74 RVVLANASGSANASDPAWDFASALFFASTLITTVGYGYTTPLTDAGKAFSIAFALLGVPT 133
Query: 145 TLLFLTAVVQRITVHVTRRPVLYFHIRWGFSKQVVAIVHAVLLGFVTVSCFFFIPAAVFS 204
T+L LTA QR+++ +T P+ + +RWG+ + A H V L V V+ F +PA +F+
Sbjct: 134 TMLLLTASAQRLSLLLTHVPLSWLSMRWGWDPRRAACWHLVALLGVVVTVCFLVPAVIFA 193
Query: 205 VLEDDWNFLESFYFCFISLSTIGLGDYVPGEGYNQKFRELYKIGITCYLLLGLIAMLVVL 264
LE+ W+FL++FYFCFISLSTIGLGDYVPGE Q +R LYK+ +T YL LGL+AM++VL
Sbjct: 194 HLEEAWSFLDAFYFCFISLSTIGLGDYVPGEAPGQPYRALYKVLVTVYLFLGLVAMVLVL 253
Query: 265 ETFCELHELKKFRKMFYVK-------KDKDEDQVHII-----EHDQLSFSSITDQAA 309
+TF + +L ++ + ++D+V I+ H QLS SS TD A+
Sbjct: 254 QTFRHVSDLHGLTELILLPPPCPASFNADEDDRVDILGPQPESHQQLSASSHTDYAS 310
>gi|16118231 potassium channel, subfamily K, member 7 isoform A
[Homo sapiens]
Length = 307
Score = 202 bits (515), Expect = 3e-52
Identities = 120/290 (41%), Positives = 167/290 (57%), Gaps = 5/290 (1%)
Query: 23 FGFLVLGYLLYLVFGAVVFSSVELPYEDLLRQELRKLKRRFLEEHE-CLSEQQLEQFLGR 81
+G LV+ +LL L GAVVF ++E P L+ ELR F EH CL LE+ LG
Sbjct: 10 YGLLVVAHLLALGLGAVVFQALEGPPACRLQAELRAELAAFQAEHRACLPPGALEELLGT 69
Query: 82 VLEASNYGVSVLSNASGNWNWDFTSALFFASTVLSTTGYGHTVPLSDGGKAFCIIYSVIG 141
L +GVS L N+S WD SAL FA+++L+TTGYGH PLS GGKAFC++Y+ +G
Sbjct: 70 ALATQAHGVSTLGNSSEGRTWDLPSALLFAASILTTTGYGHMAPLSPGGKAFCMVYAALG 129
Query: 142 IPFTLLFLTAVVQRITVHVTRRPVLYFHIRWGFSKQVVAIVHAVLLGFVTVSCFFFIPAA 201
+P +L L A ++ + V RP + + W S A++ AV LG + S F +PA
Sbjct: 130 LPASLA-LVATLRHCLLPVLSRPRAWVAVHWQLSPARAALLQAVALGLLVASSFVLLPAL 188
Query: 202 VFSVLEDDWNFLESFYFCFISLSTIGLGDYVPGEG--YNQKFRELYKIGITCYLLLGLIA 259
V L+ D + L + YFCF SLSTIGL D +PG G + L ++ + YLLLGL+A
Sbjct: 189 VLWGLQGDCSLLGAVYFCFSSLSTIGLEDLLPGRGRSLHPVIYHLGQLALLGYLLLGLLA 248
Query: 260 MLVVLETFCELHELKKFRKMFYVKKD-KDEDQVHIIEHDQLSFSSITDQA 308
ML+ +ETF EL +++ K F EDQ I+ D+L+ S++ A
Sbjct: 249 MLLAVETFSELPQVRAMGKFFRPSGPVTAEDQGGILGQDELALSTLPPAA 298
>gi|5031821 potassium channel, subfamily K, member 7 isoform C [Homo
sapiens]
Length = 257
Score = 172 bits (436), Expect = 4e-43
Identities = 95/215 (44%), Positives = 127/215 (59%), Gaps = 2/215 (0%)
Query: 23 FGFLVLGYLLYLVFGAVVFSSVELPYEDLLRQELRKLKRRFLEEHE-CLSEQQLEQFLGR 81
+G LV+ +LL L GAVVF ++E P L+ ELR F EH CL LE+ LG
Sbjct: 10 YGLLVVAHLLALGLGAVVFQALEGPPACRLQAELRAELAAFQAEHRACLPPGALEELLGT 69
Query: 82 VLEASNYGVSVLSNASGNWNWDFTSALFFASTVLSTTGYGHTVPLSDGGKAFCIIYSVIG 141
L +GVS L N+S WD SAL FA+++L+TTGYGH PLS GGKAFC++Y+ +G
Sbjct: 70 ALATQAHGVSTLGNSSEGRTWDLPSALLFAASILTTTGYGHMAPLSPGGKAFCMVYAALG 129
Query: 142 IPFTLLFLTAVVQRITVHVTRRPVLYFHIRWGFSKQVVAIVHAVLLGFVTVSCFFFIPAA 201
+P +L L A ++ + V RP + + W S A++ AV LG + S F +PA
Sbjct: 130 LPASLA-LVATLRHCLLPVLSRPRAWVAVHWQLSPARAALLQAVALGLLVASSFVLLPAL 188
Query: 202 VFSVLEDDWNFLESFYFCFISLSTIGLGDYVPGEG 236
V L+ D + L + YFCF SLSTIGL D +PG G
Sbjct: 189 VLWGLQGDCSLLGAVYFCFSSLSTIGLEDLLPGRG 223
>gi|16118235 potassium channel, subfamily K, member 7 isoform B
[Homo sapiens]
Length = 252
Score = 172 bits (436), Expect = 4e-43
Identities = 95/215 (44%), Positives = 127/215 (59%), Gaps = 2/215 (0%)
Query: 23 FGFLVLGYLLYLVFGAVVFSSVELPYEDLLRQELRKLKRRFLEEHE-CLSEQQLEQFLGR 81
+G LV+ +LL L GAVVF ++E P L+ ELR F EH CL LE+ LG
Sbjct: 10 YGLLVVAHLLALGLGAVVFQALEGPPACRLQAELRAELAAFQAEHRACLPPGALEELLGT 69
Query: 82 VLEASNYGVSVLSNASGNWNWDFTSALFFASTVLSTTGYGHTVPLSDGGKAFCIIYSVIG 141
L +GVS L N+S WD SAL FA+++L+TTGYGH PLS GGKAFC++Y+ +G
Sbjct: 70 ALATQAHGVSTLGNSSEGRTWDLPSALLFAASILTTTGYGHMAPLSPGGKAFCMVYAALG 129
Query: 142 IPFTLLFLTAVVQRITVHVTRRPVLYFHIRWGFSKQVVAIVHAVLLGFVTVSCFFFIPAA 201
+P +L L A ++ + V RP + + W S A++ AV LG + S F +PA
Sbjct: 130 LPASLA-LVATLRHCLLPVLSRPRAWVAVHWQLSPARAALLQAVALGLLVASSFVLLPAL 188
Query: 202 VFSVLEDDWNFLESFYFCFISLSTIGLGDYVPGEG 236
V L+ D + L + YFCF SLSTIGL D +PG G
Sbjct: 189 VLWGLQGDCSLLGAVYFCFSSLSTIGLEDLLPGRG 223
>gi|16118233 potassium channel, subfamily K, member 7 isoform B
[Homo sapiens]
Length = 252
Score = 172 bits (436), Expect = 4e-43
Identities = 95/215 (44%), Positives = 127/215 (59%), Gaps = 2/215 (0%)
Query: 23 FGFLVLGYLLYLVFGAVVFSSVELPYEDLLRQELRKLKRRFLEEHE-CLSEQQLEQFLGR 81
+G LV+ +LL L GAVVF ++E P L+ ELR F EH CL LE+ LG
Sbjct: 10 YGLLVVAHLLALGLGAVVFQALEGPPACRLQAELRAELAAFQAEHRACLPPGALEELLGT 69
Query: 82 VLEASNYGVSVLSNASGNWNWDFTSALFFASTVLSTTGYGHTVPLSDGGKAFCIIYSVIG 141
L +GVS L N+S WD SAL FA+++L+TTGYGH PLS GGKAFC++Y+ +G
Sbjct: 70 ALATQAHGVSTLGNSSEGRTWDLPSALLFAASILTTTGYGHMAPLSPGGKAFCMVYAALG 129
Query: 142 IPFTLLFLTAVVQRITVHVTRRPVLYFHIRWGFSKQVVAIVHAVLLGFVTVSCFFFIPAA 201
+P +L L A ++ + V RP + + W S A++ AV LG + S F +PA
Sbjct: 130 LPASLA-LVATLRHCLLPVLSRPRAWVAVHWQLSPARAALLQAVALGLLVASSFVLLPAL 188
Query: 202 VFSVLEDDWNFLESFYFCFISLSTIGLGDYVPGEG 236
V L+ D + L + YFCF SLSTIGL D +PG G
Sbjct: 189 VLWGLQGDCSLLGAVYFCFSSLSTIGLEDLLPGRG 223
>gi|205360983 potassium channel, subfamily K, member 16 isoform 3
[Homo sapiens]
Length = 294
Score = 155 bits (393), Expect = 4e-38
Identities = 86/239 (35%), Positives = 136/239 (56%), Gaps = 4/239 (1%)
Query: 26 LVLGYLLYLVFGAVVFSSVELPYEDLLRQELRKLKRRFLEEHECLSEQQLEQFLGRVLEA 85
L+L Y+ YL+ GA +F +E E R + + K RFLE + CL + +EQF+ ++EA
Sbjct: 17 LLLAYVCYLLLGATIFQLLERQAEAQSRDQFQLEKLRFLENYTCLDQWAMEQFVQVIMEA 76
Query: 86 SNYGVSVLSNASGNWNWDFTSALFFASTVLSTTGYGHTVPLSDGGKAFCIIYSVIGIPFT 145
GV+ N++ NWDF S+ FFA TV++T GYG+ P ++ G+ FC+ Y+++GIP
Sbjct: 77 WVKGVNPKGNSTNPSNWDFGSSFFFAGTVVTTIGYGNLAPSTEAGQVFCVFYALLGIPLN 136
Query: 146 LLFLTAVVQRITVHVTRRPVLYFHIRWGFSKQVVAIVHAVLLGFVTVSCFFFIPAAVFSV 205
++FL + + H+ R QV+ + + LG + + F P VFS
Sbjct: 137 VIFLNHLGTGLRAHLAAIERWEDRPRRSQVLQVLGLALFLTLGTLVILIF---PPMVFSH 193
Query: 206 LEDDWNFLESFYFCFISLSTIGLGDYVPGEGYNQKFRELYKIGITCYLLLGLIAMLVVL 264
+E W+F E FYF FI+LSTIG GDYV G ++ + +Y+ ++LLGL + ++L
Sbjct: 194 VE-GWSFSEGFYFAFITLSTIGFGDYVVGTDPSKHYISVYRSLAAIWILLGLAWLALIL 251
>gi|14149764 potassium channel, subfamily K, member 16 isoform 2
[Homo sapiens]
Length = 309
Score = 155 bits (393), Expect = 4e-38
Identities = 86/239 (35%), Positives = 136/239 (56%), Gaps = 4/239 (1%)
Query: 26 LVLGYLLYLVFGAVVFSSVELPYEDLLRQELRKLKRRFLEEHECLSEQQLEQFLGRVLEA 85
L+L Y+ YL+ GA +F +E E R + + K RFLE + CL + +EQF+ ++EA
Sbjct: 17 LLLAYVCYLLLGATIFQLLERQAEAQSRDQFQLEKLRFLENYTCLDQWAMEQFVQVIMEA 76
Query: 86 SNYGVSVLSNASGNWNWDFTSALFFASTVLSTTGYGHTVPLSDGGKAFCIIYSVIGIPFT 145
GV+ N++ NWDF S+ FFA TV++T GYG+ P ++ G+ FC+ Y+++GIP
Sbjct: 77 WVKGVNPKGNSTNPSNWDFGSSFFFAGTVVTTIGYGNLAPSTEAGQVFCVFYALLGIPLN 136
Query: 146 LLFLTAVVQRITVHVTRRPVLYFHIRWGFSKQVVAIVHAVLLGFVTVSCFFFIPAAVFSV 205
++FL + + H+ R QV+ + + LG + + F P VFS
Sbjct: 137 VIFLNHLGTGLRAHLAAIERWEDRPRRSQVLQVLGLALFLTLGTLVILIF---PPMVFSH 193
Query: 206 LEDDWNFLESFYFCFISLSTIGLGDYVPGEGYNQKFRELYKIGITCYLLLGLIAMLVVL 264
+E W+F E FYF FI+LSTIG GDYV G ++ + +Y+ ++LLGL + ++L
Sbjct: 194 VE-GWSFSEGFYFAFITLSTIGFGDYVVGTDPSKHYISVYRSLAAIWILLGLAWLALIL 251
>gi|20143946 potassium channel, subfamily K, member 10 isoform 3
[Homo sapiens]
Length = 543
Score = 151 bits (382), Expect = 7e-37
Identities = 84/239 (35%), Positives = 132/239 (55%), Gaps = 8/239 (3%)
Query: 31 LLYLVFGAVVFSSVELPYEDLLRQELRKLKRRFLEEHECLSEQQLEQFLGRVLEASNYGV 90
++YLV G +VF ++E P+E + + K FL +H C+S Q+LE + L+A N GV
Sbjct: 85 VVYLVTGGLVFRALEQPFESSQKNTIALEKAEFLRDHVCVSPQELETLIQHALDADNAGV 144
Query: 91 SVLSNASGNWN-WDFTSALFFASTVLSTTGYGHTVPLSDGGKAFCIIYSVIGIPFTLLFL 149
S + N+S N + WD SA FFA TV++T GYG+ P ++GGK FCI+Y++ GIP L
Sbjct: 145 SPIGNSSNNSSHWDLGSAFFFAGTVITTIGYGNIAPSTEGGKIFCILYAIFGIPLFGFLL 204
Query: 150 TAVVQRITVHVTRRPVLYFHI--RWGFSKQVVAIVHAVLLGFVTVSCFFF--IPAAVFSV 205
+ ++ + + + S+ + ++ +L F+ C F IPA +F
Sbjct: 205 AGIGDQLGTIFGKSIARVEKVFRKKQVSQTKIRVISTIL--FILAGCIVFVTIPAVIFKY 262
Query: 206 LEDDWNFLESFYFCFISLSTIGLGDYVPGEGYNQKFRELYKIGITCYLLLGLIAMLVVL 264
+E W LES YF ++L+T+G GD+V G +RE YK + ++L+GL VL
Sbjct: 263 IE-GWTALESIYFVVVTLTTVGFGDFVAGGNAGINYREWYKPLVWFWILVGLAYFAAVL 320
>gi|20143944 potassium channel, subfamily K, member 10 isoform 2
[Homo sapiens]
Length = 543
Score = 151 bits (382), Expect = 7e-37
Identities = 84/239 (35%), Positives = 132/239 (55%), Gaps = 8/239 (3%)
Query: 31 LLYLVFGAVVFSSVELPYEDLLRQELRKLKRRFLEEHECLSEQQLEQFLGRVLEASNYGV 90
++YLV G +VF ++E P+E + + K FL +H C+S Q+LE + L+A N GV
Sbjct: 85 VVYLVTGGLVFRALEQPFESSQKNTIALEKAEFLRDHVCVSPQELETLIQHALDADNAGV 144
Query: 91 SVLSNASGNWN-WDFTSALFFASTVLSTTGYGHTVPLSDGGKAFCIIYSVIGIPFTLLFL 149
S + N+S N + WD SA FFA TV++T GYG+ P ++GGK FCI+Y++ GIP L
Sbjct: 145 SPIGNSSNNSSHWDLGSAFFFAGTVITTIGYGNIAPSTEGGKIFCILYAIFGIPLFGFLL 204
Query: 150 TAVVQRITVHVTRRPVLYFHI--RWGFSKQVVAIVHAVLLGFVTVSCFFF--IPAAVFSV 205
+ ++ + + + S+ + ++ +L F+ C F IPA +F
Sbjct: 205 AGIGDQLGTIFGKSIARVEKVFRKKQVSQTKIRVISTIL--FILAGCIVFVTIPAVIFKY 262
Query: 206 LEDDWNFLESFYFCFISLSTIGLGDYVPGEGYNQKFRELYKIGITCYLLLGLIAMLVVL 264
+E W LES YF ++L+T+G GD+V G +RE YK + ++L+GL VL
Sbjct: 263 IE-GWTALESIYFVVVTLTTVGFGDFVAGGNAGINYREWYKPLVWFWILVGLAYFAAVL 320
>gi|10863961 potassium channel, subfamily K, member 10 isoform 1
[Homo sapiens]
Length = 538
Score = 151 bits (382), Expect = 7e-37
Identities = 84/239 (35%), Positives = 132/239 (55%), Gaps = 8/239 (3%)
Query: 31 LLYLVFGAVVFSSVELPYEDLLRQELRKLKRRFLEEHECLSEQQLEQFLGRVLEASNYGV 90
++YLV G +VF ++E P+E + + K FL +H C+S Q+LE + L+A N GV
Sbjct: 80 VVYLVTGGLVFRALEQPFESSQKNTIALEKAEFLRDHVCVSPQELETLIQHALDADNAGV 139
Query: 91 SVLSNASGNWN-WDFTSALFFASTVLSTTGYGHTVPLSDGGKAFCIIYSVIGIPFTLLFL 149
S + N+S N + WD SA FFA TV++T GYG+ P ++GGK FCI+Y++ GIP L
Sbjct: 140 SPIGNSSNNSSHWDLGSAFFFAGTVITTIGYGNIAPSTEGGKIFCILYAIFGIPLFGFLL 199
Query: 150 TAVVQRITVHVTRRPVLYFHI--RWGFSKQVVAIVHAVLLGFVTVSCFFF--IPAAVFSV 205
+ ++ + + + S+ + ++ +L F+ C F IPA +F
Sbjct: 200 AGIGDQLGTIFGKSIARVEKVFRKKQVSQTKIRVISTIL--FILAGCIVFVTIPAVIFKY 257
Query: 206 LEDDWNFLESFYFCFISLSTIGLGDYVPGEGYNQKFRELYKIGITCYLLLGLIAMLVVL 264
+E W LES YF ++L+T+G GD+V G +RE YK + ++L+GL VL
Sbjct: 258 IE-GWTALESIYFVVVTLTTVGFGDFVAGGNAGINYREWYKPLVWFWILVGLAYFAAVL 315
>gi|205360971 potassium channel, subfamily K, member 16 isoform 1
[Homo sapiens]
Length = 322
Score = 147 bits (371), Expect = 1e-35
Identities = 81/213 (38%), Positives = 121/213 (56%), Gaps = 4/213 (1%)
Query: 26 LVLGYLLYLVFGAVVFSSVELPYEDLLRQELRKLKRRFLEEHECLSEQQLEQFLGRVLEA 85
L+L Y+ YL+ GA +F +E E R + + K RFLE + CL + +EQF+ ++EA
Sbjct: 17 LLLAYVCYLLLGATIFQLLERQAEAQSRDQFQLEKLRFLENYTCLDQWAMEQFVQVIMEA 76
Query: 86 SNYGVSVLSNASGNWNWDFTSALFFASTVLSTTGYGHTVPLSDGGKAFCIIYSVIGIPFT 145
GV+ N++ NWDF S+ FFA TV++T GYG+ P ++ G+ FC+ Y+++GIP
Sbjct: 77 WVKGVNPKGNSTNPSNWDFGSSFFFAGTVVTTIGYGNLAPSTEAGQVFCVFYALLGIPLN 136
Query: 146 LLFLTAVVQRITVHVTRRPVLYFHIRWGFSKQVVAIVHAVLLGFVTVSCFFFIPAAVFSV 205
++FL + + H+ R QV+ + + LG + + F P VFS
Sbjct: 137 VIFLNHLGTGLRAHLAAIERWEDRPRRSQVLQVLGLALFLTLGTLVILIF---PPMVFSH 193
Query: 206 LEDDWNFLESFYFCFISLSTIGLGDYVPGEGYN 238
+E W+F E FYF FI+LSTIG GDYV G N
Sbjct: 194 VE-GWSFSEGFYFAFITLSTIGFGDYVVGHPLN 225
Score = 29.3 bits (64), Expect = 5.2
Identities = 13/39 (33%), Positives = 20/39 (51%)
Query: 209 DWNFLESFYFCFISLSTIGLGDYVPGEGYNQKFRELYKI 247
+W+F SF+F ++TIG G+ P Q F Y +
Sbjct: 92 NWDFGSSFFFAGTVVTTIGYGNLAPSTEAGQVFCVFYAL 130
>gi|205360973 potassium channel, subfamily K, member 16 isoform 4
[Homo sapiens]
Length = 262
Score = 146 bits (368), Expect = 3e-35
Identities = 80/209 (38%), Positives = 120/209 (57%), Gaps = 4/209 (1%)
Query: 26 LVLGYLLYLVFGAVVFSSVELPYEDLLRQELRKLKRRFLEEHECLSEQQLEQFLGRVLEA 85
L+L Y+ YL+ GA +F +E E R + + K RFLE + CL + +EQF+ ++EA
Sbjct: 17 LLLAYVCYLLLGATIFQLLERQAEAQSRDQFQLEKLRFLENYTCLDQWAMEQFVQVIMEA 76
Query: 86 SNYGVSVLSNASGNWNWDFTSALFFASTVLSTTGYGHTVPLSDGGKAFCIIYSVIGIPFT 145
GV+ N++ NWDF S+ FFA TV++T GYG+ P ++ G+ FC+ Y+++GIP
Sbjct: 77 WVKGVNPKGNSTNPSNWDFGSSFFFAGTVVTTIGYGNLAPSTEAGQVFCVFYALLGIPLN 136
Query: 146 LLFLTAVVQRITVHVTRRPVLYFHIRWGFSKQVVAIVHAVLLGFVTVSCFFFIPAAVFSV 205
++FL + + H+ R QV+ + + LG + + F P VFS
Sbjct: 137 VIFLNHLGTGLRAHLAAIERWEDRPRRSQVLQVLGLALFLTLGTLVILIF---PPMVFSH 193
Query: 206 LEDDWNFLESFYFCFISLSTIGLGDYVPG 234
+E W+F E FYF FI+LSTIG GDYV G
Sbjct: 194 VE-GWSFSEGFYFAFITLSTIGFGDYVVG 221
Score = 29.3 bits (64), Expect = 5.2
Identities = 13/39 (33%), Positives = 20/39 (51%)
Query: 209 DWNFLESFYFCFISLSTIGLGDYVPGEGYNQKFRELYKI 247
+W+F SF+F ++TIG G+ P Q F Y +
Sbjct: 92 NWDFGSSFFFAGTVVTTIGYGNLAPSTEAGQVFCVFYAL 130
>gi|14589851 potassium channel, subfamily K, member 2 isoform b
[Homo sapiens]
Length = 411
Score = 145 bits (366), Expect = 5e-35
Identities = 84/245 (34%), Positives = 141/245 (57%), Gaps = 11/245 (4%)
Query: 25 FLVLGYLLYLVFGAVVFSSVELPYEDLLRQELRKLKRRFLEEHECLSEQQLEQFLGRVLE 84
FLV+ +LYL+ GA VF ++E P+E R + K+ F+ +H C++ +L++ + +++
Sbjct: 51 FLVV--VLYLIIGATVFKALEQPHEISQRTTIVIQKQTFISQHSCVNSTELDELIQQIVA 108
Query: 85 ASNYGVSVLSNASGN-WNWDFTSALFFASTVLSTTGYGHTVPLSDGGKAFCIIYSVIGIP 143
A N G+ L N S +WD S+ FFA TV++T G+G+ P ++GGK FCIIY+++GIP
Sbjct: 109 AINAGIIPLGNTSNQISHWDLGSSFFFAGTVITTIGFGNISPRTEGGKIFCIIYALLGIP 168
Query: 144 FTLLFLTAVVQRITVHVTR--RPVLYFHIRWGFSKQVVAIVHAVLLGFVTVSCFFFI--P 199
L V ++ + V I+W S+ + I+ ++ F+ C F+ P
Sbjct: 169 LFGFLLAGVGDQLGTIFGKGIAKVEDTFIKWNVSQTKIRIISTII--FILFGCVLFVALP 226
Query: 200 AAVFSVLEDDWNFLESFYFCFISLSTIGLGDYVPGEGYNQKFRELYKIGITCYLLLGLIA 259
A +F +E W+ L++ YF I+L+TIG GDYV G G + ++ + YK + ++L+GL
Sbjct: 227 AIIFKHIE-GWSALDAIYFVVITLTTIGFGDYVAG-GSDIEYLDFYKPVVWFWILVGLAY 284
Query: 260 MLVVL 264
VL
Sbjct: 285 FAAVL 289
>gi|126365795 potassium channel, subfamily K, member 2 isoform c
[Homo sapiens]
Length = 426
Score = 145 bits (366), Expect = 5e-35
Identities = 84/245 (34%), Positives = 141/245 (57%), Gaps = 11/245 (4%)
Query: 25 FLVLGYLLYLVFGAVVFSSVELPYEDLLRQELRKLKRRFLEEHECLSEQQLEQFLGRVLE 84
FLV+ +LYL+ GA VF ++E P+E R + K+ F+ +H C++ +L++ + +++
Sbjct: 66 FLVV--VLYLIIGATVFKALEQPHEISQRTTIVIQKQTFISQHSCVNSTELDELIQQIVA 123
Query: 85 ASNYGVSVLSNASGN-WNWDFTSALFFASTVLSTTGYGHTVPLSDGGKAFCIIYSVIGIP 143
A N G+ L N S +WD S+ FFA TV++T G+G+ P ++GGK FCIIY+++GIP
Sbjct: 124 AINAGIIPLGNTSNQISHWDLGSSFFFAGTVITTIGFGNISPRTEGGKIFCIIYALLGIP 183
Query: 144 FTLLFLTAVVQRITVHVTR--RPVLYFHIRWGFSKQVVAIVHAVLLGFVTVSCFFFI--P 199
L V ++ + V I+W S+ + I+ ++ F+ C F+ P
Sbjct: 184 LFGFLLAGVGDQLGTIFGKGIAKVEDTFIKWNVSQTKIRIISTII--FILFGCVLFVALP 241
Query: 200 AAVFSVLEDDWNFLESFYFCFISLSTIGLGDYVPGEGYNQKFRELYKIGITCYLLLGLIA 259
A +F +E W+ L++ YF I+L+TIG GDYV G G + ++ + YK + ++L+GL
Sbjct: 242 AIIFKHIE-GWSALDAIYFVVITLTTIGFGDYVAG-GSDIEYLDFYKPVVWFWILVGLAY 299
Query: 260 MLVVL 264
VL
Sbjct: 300 FAAVL 304
>gi|62912487 potassium channel, subfamily K, member 2 isoform a
[Homo sapiens]
Length = 422
Score = 145 bits (366), Expect = 5e-35
Identities = 84/245 (34%), Positives = 141/245 (57%), Gaps = 11/245 (4%)
Query: 25 FLVLGYLLYLVFGAVVFSSVELPYEDLLRQELRKLKRRFLEEHECLSEQQLEQFLGRVLE 84
FLV+ +LYL+ GA VF ++E P+E R + K+ F+ +H C++ +L++ + +++
Sbjct: 62 FLVV--VLYLIIGATVFKALEQPHEISQRTTIVIQKQTFISQHSCVNSTELDELIQQIVA 119
Query: 85 ASNYGVSVLSNASGN-WNWDFTSALFFASTVLSTTGYGHTVPLSDGGKAFCIIYSVIGIP 143
A N G+ L N S +WD S+ FFA TV++T G+G+ P ++GGK FCIIY+++GIP
Sbjct: 120 AINAGIIPLGNTSNQISHWDLGSSFFFAGTVITTIGFGNISPRTEGGKIFCIIYALLGIP 179
Query: 144 FTLLFLTAVVQRITVHVTR--RPVLYFHIRWGFSKQVVAIVHAVLLGFVTVSCFFFI--P 199
L V ++ + V I+W S+ + I+ ++ F+ C F+ P
Sbjct: 180 LFGFLLAGVGDQLGTIFGKGIAKVEDTFIKWNVSQTKIRIISTII--FILFGCVLFVALP 237
Query: 200 AAVFSVLEDDWNFLESFYFCFISLSTIGLGDYVPGEGYNQKFRELYKIGITCYLLLGLIA 259
A +F +E W+ L++ YF I+L+TIG GDYV G G + ++ + YK + ++L+GL
Sbjct: 238 AIIFKHIE-GWSALDAIYFVVITLTTIGFGDYVAG-GSDIEYLDFYKPVVWFWILVGLAY 295
Query: 260 MLVVL 264
VL
Sbjct: 296 FAAVL 300
>gi|15718767 TRAAK [Homo sapiens]
Length = 393
Score = 144 bits (364), Expect = 8e-35
Identities = 87/256 (33%), Positives = 141/256 (55%), Gaps = 12/256 (4%)
Query: 18 RSAWCFGFLVLGYLLYLVFGAVVFSSVELPYEDLLRQELRKLKRRFLEEHECLSEQQLEQ 77
RS L L LLYLV GA+VF ++E P+E ++EL +++ +FL H C+S+Q+L
Sbjct: 2 RSTTLLALLAL-VLLYLVSGALVFRALEQPHEQQAQRELGEVREKFLRAHPCVSDQELGL 60
Query: 78 FLGRVLEASNYGVSVLSNASGNWN---WDFTSALFFASTVLSTTGYGHTVPLSDGGKAFC 134
+ V +A G +N++ N + WD SA FF+ T+++T GYG+ +D G+ FC
Sbjct: 61 LIKEVADALGGGADPETNSTSNSSHSAWDLGSAFFFSGTIITTIGYGNVALRTDAGRLFC 120
Query: 135 IIYSVIGIPFTLLFLTAVVQRITVHVTR--RPVLYFHIRWGFSKQVVAIVHAVLLGFVTV 192
I Y+++GIP + L V R+ + + ++W ++V ++ A+L F+ +
Sbjct: 121 IFYALVGIPLFGILLAGVGDRLGSSLRHGIGHIEAIFLKWHVPPELVRVLSAML--FLLI 178
Query: 193 SCFFFI--PAAVFSVLEDDWNFLESFYFCFISLSTIGLGDYVPGEGYNQKFRELYKIGIT 250
C F+ P VF +E DW+ LE+ YF ++L+T+G GDYV G Q Y+ +
Sbjct: 179 GCLLFVLTPTFVFCYME-DWSKLEAIYFVIVTLTTVGFGDYVAGADPRQD-SPAYQPLVW 236
Query: 251 CYLLLGLIAMLVVLET 266
++LLGL VL T
Sbjct: 237 FWILLGLAYFASVLTT 252
>gi|4504851 potassium channel, subfamily K, member 5 [Homo sapiens]
Length = 499
Score = 133 bits (335), Expect = 2e-31
Identities = 86/279 (30%), Positives = 149/279 (53%), Gaps = 26/279 (9%)
Query: 26 LVLGYLLYLVFGAVVFSSVELPYEDLLRQELRKLKRRFLEEHECLSEQQLEQFLGRVLEA 85
L + YL GA +F +E P+ ++ K L+E CL ++ L++ L V +A
Sbjct: 8 LTSAIIFYLAIGAAIFEVLEEPHWKEAKKNYYTQKLHLLKEFPCLGQEGLDKILEVVSDA 67
Query: 86 SNYGVSVLSNASGNWNWDFTSALFFASTVLSTTGYGHTVPLSDGGKAFCIIYSVIGIPFT 145
+ GV++ N + N NW++ +A+ FA+TV++T GYG+ P + G+ FC+ Y + G+P
Sbjct: 68 AGQGVAITGNQTFN-NWNWPNAMIFAATVITTIGYGNVAPKTPAGRLFCVFYGLFGVPLC 126
Query: 146 LLFLTAV-------VQRITVHVTRRPVLYFHIRWGFSKQVVAIVHAVLLGFVTVSCFFFI 198
L +++A+ +R+ +T+R V + + V+ IV VL+ V I
Sbjct: 127 LTWISALGKFFGGRAKRLGQFLTKRGVSLRKAQ--ITCTVIFIVWGVLVHLV-------I 177
Query: 199 PAAVFSVLEDDWNFLESFYFCFISLSTIGLGDYVPGEGYNQKFRELYKIGITCYLLLGL- 257
P VF V E WN++E Y+ FI++STIG GD+V G + + LY+ + ++ LGL
Sbjct: 178 PPFVFMVTE-GWNYIEGLYYSFITISTIGFGDFVAGVNPSANYHALYRYFVELWIYLGLA 236
Query: 258 -IAMLV--VLETFCELHE-LKKFRKMFYVKKDKDEDQVH 292
+++ V + F E+H+ +KK R+ +K+ E H
Sbjct: 237 WLSLFVNWKVSMFVEVHKAIKKRRRR---RKESFESSPH 272
>gi|4504849 potassium channel, subfamily K, member 3 [Homo sapiens]
Length = 394
Score = 120 bits (300), Expect = 2e-27
Identities = 75/208 (36%), Positives = 116/208 (55%), Gaps = 13/208 (6%)
Query: 26 LVLGYLLYLVFGAVVFSSVELPYEDLLRQELRKLKRRFLEEHECLSEQQLEQFLGRVLEA 85
L++ YL+ GA VF ++E E + RQ L +L+++ L LS+ E+ VL
Sbjct: 11 LIVCTFTYLLVGAAVFDALESEPELIERQRL-ELRQQELRARYNLSQGGYEELERVVLRL 69
Query: 86 SNYGVSVLSNASGNWNWDFTSALFFASTVLSTTGYGHTVPLSDGGKAFCIIYSVIGIPFT 145
+ V W F + +FA TV++T GYGH P +DGGK FC+ Y+++GIP T
Sbjct: 70 KPHKAGV--------QWRFAGSFYFAITVITTIGYGHAAPSTDGGKVFCMFYALLGIPLT 121
Query: 146 LLFLTAVVQRITVHVTRRPVLYFHIR-WGFSKQVVAIVHAVLLGFVTVSCFFFIPAAVFS 204
L+ ++ +RI V R +L+ + G + V++ + VL+GF + I AA FS
Sbjct: 122 LVMFQSLGERINTLV--RYLLHRAKKGLGMRRADVSMANMVLIGFFSCISTLCIGAAAFS 179
Query: 205 VLEDDWNFLESFYFCFISLSTIGLGDYV 232
E W F +++Y+CFI+L+TIG GDYV
Sbjct: 180 HYE-HWTFFQAYYYCFITLTTIGFGDYV 206
Score = 32.0 bits (71), Expect = 0.80
Identities = 23/75 (30%), Positives = 30/75 (40%), Gaps = 16/75 (21%)
Query: 210 WNFLESFYFCFISLSTIGLGDYVPGEGYNQKFRELYKIGITCYLLLGLIAMLVVLETFCE 269
W F SFYF ++TIG G P K+ Y LLG+ LV+ ++ E
Sbjct: 78 WRFAGSFYFAITVITTIGYGHAAPSTDGG-------KVFCMFYALLGIPLTLVMFQSLGE 130
Query: 270 ---------LHELKK 275
LH KK
Sbjct: 131 RINTLVRYLLHRAKK 145
Score = 28.5 bits (62), Expect = 8.9
Identities = 18/63 (28%), Positives = 26/63 (41%), Gaps = 8/63 (12%)
Query: 101 NWDFTSALFFASTVLSTTGYGHTVPLSDGGK--------AFCIIYSVIGIPFTLLFLTAV 152
+W F A ++ L+T G+G V L AF +Y + G+ FL V
Sbjct: 183 HWTFFQAYYYCFITLTTIGFGDYVALQKDQALQTQPQYVAFSFVYILTGLTVIGAFLNLV 242
Query: 153 VQR 155
V R
Sbjct: 243 VLR 245
>gi|17025230 potassium channel, subfamily K, member 17 isoform 1
[Homo sapiens]
Length = 332
Score = 120 bits (300), Expect = 2e-27
Identities = 73/246 (29%), Positives = 130/246 (52%), Gaps = 15/246 (6%)
Query: 26 LVLGYLLYLVFGAVVFSSVELPYEDLLRQELRKLKRRFLEEHECLSEQQLEQFLGRVLEA 85
L+L YL YL G VF ++E + ++ K L+ CL L+ + V++A
Sbjct: 25 LLLAYLAYLALGTGVFWTLEGRAAQDSSRSFQRDKWELLQNFTCLDRPALDSLIRDVVQA 84
Query: 86 SNYGVSVLSNASGNWNWDFTSALFFASTVLSTTGYGHTVPLSDGGKAFCIIYSVIGIPFT 145
G S+LSN + W+ + FF+ + ++T GYG+ P + + FCI ++++GIP
Sbjct: 85 YKNGASLLSNTTSMGRWELVGSFFFSVSTITTIGYGNLSPNTMAARLFCIFFALVGIPLN 144
Query: 146 LLFLTAVVQRITVHVTRRPVLYFHIRWGFSKQ------VVAIVHAVLLGFVTVSCFFFIP 199
L+ L + H+ ++ V ++ R G + Q +A A+L G + F +P
Sbjct: 145 LVVLNRL-----GHLMQQGVNHWASRLGGTWQDPDKARWLAGSGALLSGLL---LFLLLP 196
Query: 200 AAVFSVLEDDWNFLESFYFCFISLSTIGLGDYVPGEGYNQKFRELYKIGITCYLLLGLIA 259
+FS +E W++ E FYF FI+LST+G GDYV G +Q++ YK ++ ++L G+
Sbjct: 197 PLLFSHME-GWSYTEGFYFAFITLSTVGFGDYVIGMNPSQRYPLWYKNMVSLWILFGMAW 255
Query: 260 MLVVLE 265
+ ++++
Sbjct: 256 LALIIK 261
>gi|7706135 potassium channel, subfamily K, member 9 [Homo sapiens]
Length = 374
Score = 117 bits (293), Expect = 1e-26
Identities = 80/236 (33%), Positives = 127/236 (53%), Gaps = 18/236 (7%)
Query: 26 LVLGYLLYLVFGAVVFSSVELPYEDLLRQELRKLKRRFLEEHECLSE--QQLEQFLGRVL 83
L++ YL+ GA VF ++E +E ++L+ + R ++ SE +QLE +L
Sbjct: 11 LIVCTFTYLLVGAAVFDALESDHEMREEEKLKAEEIRIKGKYNISSEDYRQLELV---IL 67
Query: 84 EASNYGVSVLSNASGNWNWDFTSALFFASTVLSTTGYGHTVPLSDGGKAFCIIYSVIGIP 143
++ + V W F + +FA TV++T GYGH P +D GKAFC+ Y+V+GIP
Sbjct: 68 QSEPHRAGV--------QWKFAGSFYFAITVITTIGYGHAAPGTDAGKAFCMFYAVLGIP 119
Query: 144 FTLLFLTAVVQRITVHVTRRPVLYFHIRWGFSKQVVAIVHAVLLGFVTVSCFFFIPAAVF 203
TL+ ++ +R+ V R + G V++ + V +GF + I AA F
Sbjct: 120 LTLVMFQSLGERMNTFV-RYLLKRIKKCCGMRNTDVSMENMVTVGFFSCMGTLCIGAAAF 178
Query: 204 SVLEDDWNFLESFYFCFISLSTIGLGDYV--PGEGYNQKFRELYKIGITCYLLLGL 257
S E +W+F ++Y+CFI+L+TIG GDYV +G QK + LY Y+L+GL
Sbjct: 179 SQCE-EWSFFHAYYYCFITLTTIGFGDYVALQTKGALQK-KPLYVAFSFMYILVGL 232
>gi|11641275 potassium family, subfamily K, member 15 [Homo sapiens]
Length = 330
Score = 114 bits (285), Expect = 1e-25
Identities = 77/233 (33%), Positives = 116/233 (49%), Gaps = 12/233 (5%)
Query: 26 LVLGYLLYLVFGAVVFSSVELPYEDLLRQELRKLKRRFLEEHECLSEQQLEQFLGRVLEA 85
LVL L YL+ GA VF ++E E RQ L KR L S + + L+A
Sbjct: 11 LVLCTLCYLLVGAAVFDALESEAESG-RQRLLVQKRGALRRKFGFSAEDYRELERLALQA 69
Query: 86 SNYGVSVLSNASGNWNWDFTSALFFASTVLSTTGYGHTVPLSDGGKAFCIIYSVIGIPFT 145
+ W F + +FA TV++T GYGH P +D GK FC+ Y+++GIP T
Sbjct: 70 EPH--------RAGRQWKFPGSFYFAITVITTIGYGHAAPGTDSGKVFCMFYALLGIPLT 121
Query: 146 LLFLTAVVQRITVHVTRRPVLYFHIRWGFSKQVVAIVHAVLLGFVTVSCFFFIPAAVFSV 205
L+ ++ +R+ V RR +L G V+ + V+ G + + + A FS
Sbjct: 122 LVTFQSLGERLNA-VVRRLLLAAKCCLGLRWTCVSTENLVVAGLLACAATLALGAVAFSH 180
Query: 206 LEDDWNFLESFYFCFISLSTIGLGDYVPGEGYNQKFRELYKIGIT-CYLLLGL 257
E W F ++Y+CFI+L+TIG GD+V + R+L + + Y+LLGL
Sbjct: 181 FE-GWTFFHAYYYCFITLTTIGFGDFVALQSGEALQRKLPYVAFSFLYILLGL 232
>gi|16306555 potassium channel, subfamily K, member 13 [Homo
sapiens]
Length = 408
Score = 113 bits (282), Expect = 3e-25
Identities = 79/254 (31%), Positives = 124/254 (48%), Gaps = 25/254 (9%)
Query: 25 FLVLGYL--LYLVFGAVVFSSVELPYEDLLRQELRKLKRRFLEEHECLSEQQLEQFLGRV 82
FL+L L LYL+ GA VFS++EL +E +Q + F H LS +L FL
Sbjct: 20 FLLLAALIVLYLLGGAAVFSALELAHERQAKQRWEERLANFSRGHN-LSRDELRGFLRHY 78
Query: 83 LEASNYGVSVLSNASGNWNWDFTSALFFASTVLSTTGYGHTVPLSDGGKAFCIIYSVIGI 142
EA+ G+ V + WDFT A +F TV+ST G+G T P + GGK F I Y ++G
Sbjct: 79 EEATRAGIRVDNVRP---RWDFTGAFYFVGTVVSTIGFGMTTPATVGGKIFLIFYGLVGC 135
Query: 143 PFTLLFLTAVVQRITV------------HVTRRPVL-YFHIRWGFSKQVVAI------VH 183
T+LF ++R+ + RR L ++ +V ++ V+
Sbjct: 136 SSTILFFNLFLERLITIIAYIMKSCHQRQLRRRGALPQESLKDAGQCEVDSLAGWKPSVY 195
Query: 184 AVLLGFVTVSCFFFIPAAVFSVLEDDWNFLESFYFCFISLSTIGLGDYVPGEGYNQKFRE 243
V+L T S A+ + W++ +S YFCF++ STIG GD V + + + +
Sbjct: 196 YVMLILCTASILISCCASAMYTPIEGWSYFDSLYFCFVAFSTIGFGDLVSSQNAHYESQG 255
Query: 244 LYKIGITCYLLLGL 257
LY+ ++L+G+
Sbjct: 256 LYRFANFVFILMGV 269
>gi|205361107 potassium channel, subfamily K, member 17 isoform 2
[Homo sapiens]
Length = 271
Score = 108 bits (269), Expect = 9e-24
Identities = 67/213 (31%), Positives = 111/213 (52%), Gaps = 15/213 (7%)
Query: 26 LVLGYLLYLVFGAVVFSSVELPYEDLLRQELRKLKRRFLEEHECLSEQQLEQFLGRVLEA 85
L+L YL YL G VF ++E + ++ K L+ CL L+ + V++A
Sbjct: 25 LLLAYLAYLALGTGVFWTLEGRAAQDSSRSFQRDKWELLQNFTCLDRPALDSLIRDVVQA 84
Query: 86 SNYGVSVLSNASGNWNWDFTSALFFASTVLSTTGYGHTVPLSDGGKAFCIIYSVIGIPFT 145
G S+LSN + W+ + FF+ + ++T GYG+ P + + FCI ++++GIP
Sbjct: 85 YKNGASLLSNTTSMGRWELVGSFFFSVSTITTIGYGNLSPNTMAARLFCIFFALVGIPLN 144
Query: 146 LLFLTAVVQRITVHVTRRPVLYFHIRWGFSKQ------VVAIVHAVLLGFVTVSCFFFIP 199
L+ L + H+ ++ V ++ R G + Q +A A+L G + F +P
Sbjct: 145 LVVLNRL-----GHLMQQGVNHWASRLGGTWQDPDKARWLAGSGALLSGLL---LFLLLP 196
Query: 200 AAVFSVLEDDWNFLESFYFCFISLSTIGLGDYV 232
+FS +E W++ E FYF FI+LST+G GDYV
Sbjct: 197 PLLFSHME-GWSYTEGFYFAFITLSTVGFGDYV 228
>gi|11545761 potassium channel, subfamily K, member 12 [Homo
sapiens]
Length = 430
Score = 105 bits (262), Expect = 6e-23
Identities = 83/258 (32%), Positives = 125/258 (48%), Gaps = 33/258 (12%)
Query: 25 FLVLGYL--LYLVFGAVVFSSVELPYEDLLRQELRKLKRRFLEEHECLSEQQLEQFLGRV 82
F++L L LYLV GA VFS++E P E R R F H ++E +L FL
Sbjct: 39 FVLLAALIGLYLVAGATVFSALESPGEAEARARWGATLRNFSAAHG-VAEPELRAFLRHY 97
Query: 83 LEASNYGVSVLSNASGNWNWDFTSALFFASTVLSTTGYGHTVPLSDGGKAFCIIYSVIGI 142
A GV + WDF A +F TV+ST G+G T P + GGKAF I Y + G
Sbjct: 98 EAALAAGVRADALRP---RWDFPGAFYFVGTVVSTIGFGMTTPATVGGKAFLIAYGLFGC 154
Query: 143 PFTLLFLTAVVQRITV------------HVTRRPVLYFHIRWGFSKQVV--------AIV 182
T+LF ++RI + R +L R G + ++
Sbjct: 155 AGTILFFNLFLERIISLLAFIMRACRERQLRRSGLLPATFRRGSALSEADSLAGWKPSVY 214
Query: 183 HAVL---LGFVTVSCFFFIPAAVFSVLEDDWNFLESFYFCFISLSTIGLGDYVPGEGYNQ 239
H +L L V +SC +A+++ +E W++++S YFCF++ STIG GD V +
Sbjct: 215 HVLLILGLFAVLLSC---CASAMYTSVEG-WDYVDSLYFCFVTFSTIGFGDLVSSQHAAY 270
Query: 240 KFRELYKIGITCYLLLGL 257
+ + LY++G ++LLG+
Sbjct: 271 RNQGLYRLGNFLFILLGV 288
>gi|32469495 potassium channel, subfamily K, member 18 [Homo
sapiens]
Length = 384
Score = 60.5 bits (145), Expect = 2e-09
Identities = 41/133 (30%), Positives = 67/133 (50%), Gaps = 12/133 (9%)
Query: 24 GFLVLGYLL-YLVFGAVVFSSVE-----LPYEDLLRQELRKLKRRFLEEHECLSEQQLEQ 77
G L +L+ Y + GAVVFS++E + +D ++ + R L E + E + +
Sbjct: 23 GLCFLCFLVTYALVGAVVFSAIEDGQVLVAADDGEFEKFLEELCRILNCSETVVEDRKQD 82
Query: 78 FLGRVLEASNYGVSVLSNASGNWNWDFTSALFFASTVLSTTGYGHTVPLSDGGKAFCIIY 137
G + + + ++ W F S+LFF TV ST GYG+ P++ GK C++Y
Sbjct: 83 LQGHLQKVKPQWFNRTTH------WSFLSSLFFCCTVFSTVGYGYIYPVTRLGKYLCMLY 136
Query: 138 SVIGIPFTLLFLT 150
++ GIP L LT
Sbjct: 137 ALFGIPLMFLVLT 149
Score = 40.4 bits (93), Expect = 0.002
Identities = 20/47 (42%), Positives = 28/47 (59%), Gaps = 4/47 (8%)
Query: 186 LLGFVTVSCFFFIPAAVFSVLEDDWNFLESFYFCFISLSTIGLGDYV 232
L+ F +SC AA+ E +F +FYFCF++L+TIG GD V
Sbjct: 288 LIVFAYISC----AAAILPFWETQLDFENAFYFCFVTLTTIGFGDTV 330
Score = 33.5 bits (75), Expect = 0.28
Identities = 18/66 (27%), Positives = 32/66 (48%), Gaps = 1/66 (1%)
Query: 103 DFTSALFFASTVLSTTGYGHTVPLSDGGKAFCIIYSVIGIPFTLLFLTAVVQRITVHVTR 162
DF +A +F L+T G+G TV F IY ++G+ + V R+ + + +
Sbjct: 309 DFENAFYFCFVTLTTIGFGDTVLEHPNFFLFFSIYIIVGMEIVFIAFKLVQNRL-IDIYK 367
Query: 163 RPVLYF 168
+L+F
Sbjct: 368 NVMLFF 373
Score = 31.6 bits (70), Expect = 1.0
Identities = 19/55 (34%), Positives = 24/55 (43%), Gaps = 7/55 (12%)
Query: 210 WNFLESFYFCFISLSTIGLGDYVPGEGYNQKFRELYKIGITCYLLLGLIAMLVVL 264
W+FL S +FC ST+G GY L K Y L G+ M +VL
Sbjct: 101 WSFLSSLFFCCTVFSTVGY-------GYIYPVTRLGKYLCMLYALFGIPLMFLVL 148
>gi|240255505 potassium channel, subfamily T, member 1 [Homo
sapiens]
Length = 1235
Score = 41.2 bits (95), Expect = 0.001
Identities = 21/57 (36%), Positives = 31/57 (54%), Gaps = 3/57 (5%)
Query: 180 AIVHAVLLGFVTVSCFFFIPAAVFSVLE---DDWNFLESFYFCFISLSTIGLGDYVP 233
A+ + VL+ F T+ C F LE ++ + L SFYFC ++ ST+G GD P
Sbjct: 266 AMFNQVLILFCTLLCLVFTGTCGIQHLERAGENLSLLTSFYFCIVTFSTVGYGDVTP 322
>gi|41349443 potassium channel, subfamily T, member 2 [Homo sapiens]
Length = 1135
Score = 38.1 bits (87), Expect = 0.011
Identities = 25/81 (30%), Positives = 39/81 (48%), Gaps = 7/81 (8%)
Query: 180 AIVHAVLLGFVTVSCFFFIPAAVFSVLE---DDWNFLESFYFCFISLSTIGLGDYVPGEG 236
A+ + VL+ T+ C F LE N +S YFC ++ ST+G GD P E
Sbjct: 194 AMFNQVLILISTLLCLIFTCICGIQHLERIGKKLNLFDSLYFCIVTFSTVGFGDVTP-ET 252
Query: 237 YNQKFRELYKIGITCYLLLGL 257
++ K L+ + + C L+ L
Sbjct: 253 WSSK---LFVVAMICVALVVL 270
>gi|4504831 potassium voltage-gated channel, subfamily H, member 1
isoform 2 [Homo sapiens]
Length = 962
Score = 37.4 bits (85), Expect = 0.019
Identities = 23/89 (25%), Positives = 44/89 (49%), Gaps = 11/89 (12%)
Query: 85 ASNYGVSVLSNASGNWNWD--------FTSALFFASTVLSTTGYGHTVPLSDGGKAFCII 136
A + G N SG+ W+ + S+L+F T L++ G+G+ P +D K F +
Sbjct: 396 AMDIGTPYQFNGSGSGKWEGGPSKNSVYISSLYFTMTSLTSVGFGNIAPSTDIEKIFAVA 455
Query: 137 YSVIG-IPFTLLF--LTAVVQRITVHVTR 162
+IG + + +F +T + Q++ + R
Sbjct: 456 IMMIGSLLYATIFGNVTTIFQQMYANTNR 484
>gi|27437001 potassium voltage-gated channel, subfamily H, member 1
isoform 1 [Homo sapiens]
Length = 989
Score = 37.4 bits (85), Expect = 0.019
Identities = 23/89 (25%), Positives = 44/89 (49%), Gaps = 11/89 (12%)
Query: 85 ASNYGVSVLSNASGNWNWD--------FTSALFFASTVLSTTGYGHTVPLSDGGKAFCII 136
A + G N SG+ W+ + S+L+F T L++ G+G+ P +D K F +
Sbjct: 423 AMDIGTPYQFNGSGSGKWEGGPSKNSVYISSLYFTMTSLTSVGFGNIAPSTDIEKIFAVA 482
Query: 137 YSVIG-IPFTLLF--LTAVVQRITVHVTR 162
+IG + + +F +T + Q++ + R
Sbjct: 483 IMMIGSLLYATIFGNVTTIFQQMYANTNR 511
Database: hs.faa
Posted date: Aug 4, 2009 4:42 PM
Number of letters in database: 18,247,518
Number of sequences in database: 37,866
Lambda K H
0.327 0.141 0.434
Gapped
Lambda K H
0.267 0.0410 0.140
Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Hits to DB: 11,555,267
Number of Sequences: 37866
Number of extensions: 470967
Number of successful extensions: 2015
Number of sequences better than 10.0: 30
Number of HSP's better than 10.0 without gapping: 65
Number of HSP's successfully gapped in prelim test: 33
Number of HSP's that attempted gapping in prelim test: 1788
Number of HSP's gapped (non-prelim): 183
length of query: 336
length of database: 18,247,518
effective HSP length: 103
effective length of query: 233
effective length of database: 14,347,320
effective search space: 3342925560
effective search space used: 3342925560
T: 11
A: 40
X1: 15 ( 7.1 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 40 (21.7 bits)
S2: 62 (28.5 bits)
Search results were obtained with NCBI BLAST and RefSeq entries.
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Guide to the Human Genome
Copyright © 2010 by Stewart Scherer. All rights reserved.