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Search of human proteins with 4504817
BLASTP 2.2.11 [Jun-05-2005]
Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer,
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997),
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs", Nucleic Acids Res. 25:3389-3402.
Query= gi|4504817 potassium voltage-gated channel, shaker-related
subfamily, member 4 [Homo sapiens]
(653 letters)
Database: hs.faa
37,866 sequences; 18,247,518 total letters
Searching..................................................done
Score E
Sequences producing significant alignments: (bits) Value
gi|4504817 potassium voltage-gated channel, shaker-related subfa... 1315 0.0
gi|88758565 potassium voltage-gated channel, shaker-related subf... 667 0.0
gi|119395748 potassium voltage-gated channel subfamily A member ... 656 0.0
gi|4826782 potassium voltage-gated channel, shaker-related subfa... 652 0.0
gi|25952087 potassium voltage-gated channel, shaker-related subf... 609 e-174
gi|4504821 potassium voltage-gated channel, shaker-related subfa... 602 e-172
gi|5031819 potassium voltage-gated channel, shaker-related subfa... 570 e-162
gi|25952092 potassium voltage-gated channel, shaker-related subf... 569 e-162
gi|27436974 potassium voltage-gated channel, Shab-related subfam... 274 2e-73
gi|4826786 Shaw-related voltage-gated potassium channel protein ... 273 5e-73
gi|163792201 Shaw-related voltage-gated potassium channel protei... 273 5e-73
gi|4826784 potassium voltage-gated channel, Shab-related subfami... 270 4e-72
gi|27436981 potassium voltage-gated channel, Shal-related subfam... 266 6e-71
gi|88758576 Shaw-related voltage-gated potassium channel protein... 260 2e-69
gi|24497462 Shaw-related voltage-gated potassium channel protein... 260 2e-69
gi|24497464 Shaw-related voltage-gated potassium channel protein... 260 2e-69
gi|27436984 potassium voltage-gated channel, Shal-related subfam... 258 9e-69
gi|27436986 potassium voltage-gated channel, Shal-related subfam... 258 9e-69
gi|9789987 potassium voltage-gated channel, Shal-related subfami... 257 3e-68
gi|21217561 Shaw-related voltage-gated potassium channel protein... 247 3e-65
gi|21217563 Shaw-related voltage-gated potassium channel protein... 247 3e-65
gi|24497458 Shaw-related voltage-gated potassium channel protein... 247 3e-65
gi|24497460 Shaw-related voltage-gated potassium channel protein... 235 1e-61
gi|13492973 potassium voltage-gated channel delayed-rectifier pr... 232 7e-61
gi|25952108 potassium voltage-gated channel delayed-rectifier pr... 228 1e-59
gi|20070166 potassium voltage-gated channel, subfamily F, member... 228 2e-59
gi|45383011 potassium voltage-gated channel, delayed-rectifier, ... 222 1e-57
gi|7657289 potassium channel, subfamily V, member 1 [Homo sapiens] 219 8e-57
gi|27436988 potassium voltage-gated channel, subfamily G, member... 218 1e-56
gi|19071574 potassium voltage-gated channel, subfamily G, member... 207 2e-53
>gi|4504817 potassium voltage-gated channel, shaker-related
subfamily, member 4 [Homo sapiens]
Length = 653
Score = 1315 bits (3402), Expect = 0.0
Identities = 653/653 (100%), Positives = 653/653 (100%)
Query: 1 MEVAMVSAESSGCNSHMPYGYAAQARARERERLAHSRAAAAAAVAAATAAVEGSGGSGGG 60
MEVAMVSAESSGCNSHMPYGYAAQARARERERLAHSRAAAAAAVAAATAAVEGSGGSGGG
Sbjct: 1 MEVAMVSAESSGCNSHMPYGYAAQARARERERLAHSRAAAAAAVAAATAAVEGSGGSGGG 60
Query: 61 SHHHHQSRGACTSHDPQSSRGSRRRRRQRSEKKKAHYRQSSFPHCSDLMPSGSEEKILRE 120
SHHHHQSRGACTSHDPQSSRGSRRRRRQRSEKKKAHYRQSSFPHCSDLMPSGSEEKILRE
Sbjct: 61 SHHHHQSRGACTSHDPQSSRGSRRRRRQRSEKKKAHYRQSSFPHCSDLMPSGSEEKILRE 120
Query: 121 LSEEEEDEEEEEEEEEEGRFYYSEDDHGDECSYTDLLPQDEGGGGYSSVRYSDCCERVVI 180
LSEEEEDEEEEEEEEEEGRFYYSEDDHGDECSYTDLLPQDEGGGGYSSVRYSDCCERVVI
Sbjct: 121 LSEEEEDEEEEEEEEEEGRFYYSEDDHGDECSYTDLLPQDEGGGGYSSVRYSDCCERVVI 180
Query: 181 NVSGLRFETQMKTLAQFPETLLGDPEKRTQYFDPLRNEYFFDRNRPSFDAILYYYQSGGR 240
NVSGLRFETQMKTLAQFPETLLGDPEKRTQYFDPLRNEYFFDRNRPSFDAILYYYQSGGR
Sbjct: 181 NVSGLRFETQMKTLAQFPETLLGDPEKRTQYFDPLRNEYFFDRNRPSFDAILYYYQSGGR 240
Query: 241 LKRPVNVPFDIFTEEVKFYQLGEEALLKFREDEGFVREEEDRALPENEFKKQIWLLFEYP 300
LKRPVNVPFDIFTEEVKFYQLGEEALLKFREDEGFVREEEDRALPENEFKKQIWLLFEYP
Sbjct: 241 LKRPVNVPFDIFTEEVKFYQLGEEALLKFREDEGFVREEEDRALPENEFKKQIWLLFEYP 300
Query: 301 ESSSPARGIAIVSVLVILISIVIFCLETLPEFRDDRDLVMALSAGGHGGLLNDTSAPHLE 360
ESSSPARGIAIVSVLVILISIVIFCLETLPEFRDDRDLVMALSAGGHGGLLNDTSAPHLE
Sbjct: 301 ESSSPARGIAIVSVLVILISIVIFCLETLPEFRDDRDLVMALSAGGHGGLLNDTSAPHLE 360
Query: 361 NSGHTIFNDPFFIVETVCIVWFSFEFVVRCFACPSQALFFKNIMNIIDIVSILPYFITLG 420
NSGHTIFNDPFFIVETVCIVWFSFEFVVRCFACPSQALFFKNIMNIIDIVSILPYFITLG
Sbjct: 361 NSGHTIFNDPFFIVETVCIVWFSFEFVVRCFACPSQALFFKNIMNIIDIVSILPYFITLG 420
Query: 421 TDLAQQQGGGNGQQQQAMSFAILRIIRLVRVFRIFKLSRHSKGLQILGHTLRASMRELGL 480
TDLAQQQGGGNGQQQQAMSFAILRIIRLVRVFRIFKLSRHSKGLQILGHTLRASMRELGL
Sbjct: 421 TDLAQQQGGGNGQQQQAMSFAILRIIRLVRVFRIFKLSRHSKGLQILGHTLRASMRELGL 480
Query: 481 LIFFLFIGVILFSSAVYFAEADEPTTHFQSIPDAFWWAVVTMTTVGYGDMKPITVGGKIV 540
LIFFLFIGVILFSSAVYFAEADEPTTHFQSIPDAFWWAVVTMTTVGYGDMKPITVGGKIV
Sbjct: 481 LIFFLFIGVILFSSAVYFAEADEPTTHFQSIPDAFWWAVVTMTTVGYGDMKPITVGGKIV 540
Query: 541 GSLCAIAGVLTIALPVPVIVSNFNYFYHRETENEEQTQLTQNAVSCPYLPSNLLKKFRSS 600
GSLCAIAGVLTIALPVPVIVSNFNYFYHRETENEEQTQLTQNAVSCPYLPSNLLKKFRSS
Sbjct: 541 GSLCAIAGVLTIALPVPVIVSNFNYFYHRETENEEQTQLTQNAVSCPYLPSNLLKKFRSS 600
Query: 601 TSSSLGDKSEYLEMEEGVKESLCAKEEKCQGKGDDSETDKNNCSNAKAVETDV 653
TSSSLGDKSEYLEMEEGVKESLCAKEEKCQGKGDDSETDKNNCSNAKAVETDV
Sbjct: 601 TSSSLGDKSEYLEMEEGVKESLCAKEEKCQGKGDDSETDKNNCSNAKAVETDV 653
>gi|88758565 potassium voltage-gated channel, shaker-related
subfamily, member 3 [Homo sapiens]
Length = 575
Score = 667 bits (1720), Expect = 0.0
Identities = 351/513 (68%), Positives = 405/513 (78%), Gaps = 27/513 (5%)
Query: 158 PQDEGGGGYSSVRYS------------DCC-ERVVINVSGLRFETQMKTLAQFPETLLGD 204
P G GG RY DCC ERVVIN+SGLRFETQ+KTL QFPETLLGD
Sbjct: 73 PPQGGCGGGGCDRYEPLPPSLPAAGEQDCCGERVVINISGLRFETQLKTLCQFPETLLGD 132
Query: 205 PEKRTQYFDPLRNEYFFDRNRPSFDAILYYYQSGGRLKRPVNVPFDIFTEEVKFYQLGEE 264
P++R +YFDPLRNEYFFDRNRPSFDAILYYYQSGGR++RPVNVP DIF+EE++FYQLGEE
Sbjct: 133 PKRRMRYFDPLRNEYFFDRNRPSFDAILYYYQSGGRIRRPVNVPIDIFSEEIRFYQLGEE 192
Query: 265 ALLKFREDEGFVREEEDRALPENEFKKQIWLLFEYPESSSPARGIAIVSVLVILISIVIF 324
A+ KFREDEGF+REEE R LP +F++Q+WLLFEYPESS PARGIAIVSVLVILISIVIF
Sbjct: 193 AMEKFREDEGFLREEE-RPLPRRDFQRQVWLLFEYPESSGPARGIAIVSVLVILISIVIF 251
Query: 325 CLETLPEFRDDRDLVMALSAGGHGGLLNDTSAPHLENSGHTIFNDPFFIVETVCIVWFSF 384
CLETLPEFRD++D + S N TS +G + F+DPFF+VET+CI+WFSF
Sbjct: 252 CLETLPEFRDEKDYPASTSQDSFEAAGNSTSG---SRAGASSFSDPFFVVETLCIIWFSF 308
Query: 385 EFVVRCFACPSQALFFKNIMNIIDIVSILPYFITLGTDLAQQQGGGNGQQQQAMSFAILR 444
E +VR FACPS+A F +NIMN+IDIV+I+PYFITLGT+LA++QG G QQAMS AILR
Sbjct: 309 ELLVRFFACPSKATFSRNIMNLIDIVAIIPYFITLGTELAERQGNG----QQAMSLAILR 364
Query: 445 IIRLVRVFRIFKLSRHSKGLQILGHTLRASMRELGLLIFFLFIGVILFSSAVYFAEADEP 504
+IRLVRVFRIFKLSRHSKGLQILG TL+ASMRELGLLIFFLFIGVILFSSAVYFAEAD+P
Sbjct: 365 VIRLVRVFRIFKLSRHSKGLQILGQTLKASMRELGLLIFFLFIGVILFSSAVYFAEADDP 424
Query: 505 TTHFQSIPDAFWWAVVTMTTVGYGDMKPITVGGKIVGSLCAIAGVLTIALPVPVIVSNFN 564
T+ F SIPDAFWWAVVTMTTVGYGDM P+T+GGKIVGSLCAIAGVLTIALPVPVIVSNFN
Sbjct: 425 TSGFSSIPDAFWWAVVTMTTVGYGDMHPVTIGGKIVGSLCAIAGVLTIALPVPVIVSNFN 484
Query: 565 YFYHRETENEEQTQLTQNAVSCPYLPSNLLKKFRSSTSSSLGDKSEYLEMEE-GVKESLC 623
YFYHRETE EEQ+Q + SC +L S+ ++ R + S+S KSEY+ +EE G+ S
Sbjct: 485 YFYHRETEGEEQSQY-MHVGSCQHLSSS-AEELRKARSNSTLSKSEYMVIEEGGMNHSAF 542
Query: 624 AKEEKCQGKGDDSETDKNN---CSNAKAVETDV 653
+ G + T NN C N K + TDV
Sbjct: 543 PQTPFKTGNSTATCTTNNNPNSCVNIKKIFTDV 575
>gi|119395748 potassium voltage-gated channel subfamily A member 1
[Homo sapiens]
Length = 495
Score = 656 bits (1692), Expect = 0.0
Identities = 345/505 (68%), Positives = 400/505 (79%), Gaps = 19/505 (3%)
Query: 149 DECSYTDLLPQDEGGGGYSSVRYSDCCERVVINVSGLRFETQMKTLAQFPETLLGDPEKR 208
DE S PQD + +CCERVVIN+SGLRFETQ+KTLAQFP TLLG+P+KR
Sbjct: 10 DEASAAPGHPQDGSYPRQADHDDHECCERVVINISGLRFETQLKTLAQFPNTLLGNPKKR 69
Query: 209 TQYFDPLRNEYFFDRNRPSFDAILYYYQSGGRLKRPVNVPFDIFTEEVKFYQLGEEALLK 268
+YFDPLRNEYFFDRNRPSFDAILYYYQSGGRL+RPVNVP D+F+EE+KFY+LGEEA+ K
Sbjct: 70 MRYFDPLRNEYFFDRNRPSFDAILYYYQSGGRLRRPVNVPLDMFSEEIKFYELGEEAMEK 129
Query: 269 FREDEGFVREEEDRALPENEFKKQIWLLFEYPESSSPARGIAIVSVLVILISIVIFCLET 328
FREDEGF++EEE R LPE E+++Q+WLLFEYPESS PAR IAIVSV+VILISIVIFCLET
Sbjct: 130 FREDEGFIKEEE-RPLPEKEYQRQVWLLFEYPESSGPARVIAIVSVMVILISIVIFCLET 188
Query: 329 LPEFRDDRDLVMALSAGGHGGLLNDTSAPHLENSGHTIFNDPFFIVETVCIVWFSFEFVV 388
LPE +DD+D G +++T+ + N IF DPFFIVET+CI+WFSFE VV
Sbjct: 189 LPELKDDKDFT------GTVHRIDNTTVIYNSN----IFTDPFFIVETLCIIWFSFELVV 238
Query: 389 RCFACPSQALFFKNIMNIIDIVSILPYFITLGTDLAQQQGGGNGQQQQAMSFAILRIIRL 448
R FACPS+ FFKNIMN IDIV+I+PYFITLGT++A+Q+G G+Q A S AILR+IRL
Sbjct: 239 RFFACPSKTDFFKNIMNFIDIVAIIPYFITLGTEIAEQEGNQKGEQ--ATSLAILRVIRL 296
Query: 449 VRVFRIFKLSRHSKGLQILGHTLRASMRELGLLIFFLFIGVILFSSAVYFAEADEPTTHF 508
VRVFRIFKLSRHSKGLQILG TL+ASMRELGLLIFFLFIGVILFSSAVYFAEA+E +HF
Sbjct: 297 VRVFRIFKLSRHSKGLQILGQTLKASMRELGLLIFFLFIGVILFSSAVYFAEAEEAESHF 356
Query: 509 QSIPDAFWWAVVTMTTVGYGDMKPITVGGKIVGSLCAIAGVLTIALPVPVIVSNFNYFYH 568
SIPDAFWWAVV+MTTVGYGDM P+T+GGKIVGSLCAIAGVLTIALPVPVIVSNFNYFYH
Sbjct: 357 SSIPDAFWWAVVSMTTVGYGDMYPVTIGGKIVGSLCAIAGVLTIALPVPVIVSNFNYFYH 416
Query: 569 RETENEEQTQLTQNAVSCPYLPSNLLKKFRSSTSSSLGDKSEYLEMEEGVKESLCAKEEK 628
RETE EEQ QL VS P L S+ RSS++ S KSEY+E+EE + S+ A +
Sbjct: 417 RETEGEEQAQLLH--VSSPNLASDSDLSRRSSSTMS---KSEYMEIEEDMNNSI-AHYRQ 470
Query: 629 CQGKGDDSETDKNNCSNAKAVETDV 653
+ + T NC N + TDV
Sbjct: 471 VNIRTANCTTANQNCVNKSKLLTDV 495
>gi|4826782 potassium voltage-gated channel, shaker-related
subfamily, member 2 [Homo sapiens]
Length = 499
Score = 652 bits (1683), Expect = 0.0
Identities = 342/477 (71%), Positives = 388/477 (81%), Gaps = 16/477 (3%)
Query: 146 DHGDECSYTDLLPQDEGGGGYSSVRYSDCCERVVINVSGLRFETQMKTLAQFPETLLGDP 205
D DE + PQD Y +CCERVVIN+SGLRFETQ+KTLAQFPETLLGDP
Sbjct: 7 DPADEAAALPGHPQDT----YDPEADHECCERVVINISGLRFETQLKTLAQFPETLLGDP 62
Query: 206 EKRTQYFDPLRNEYFFDRNRPSFDAILYYYQSGGRLKRPVNVPFDIFTEEVKFYQLGEEA 265
+KR +YFDPLRNEYFFDRNRPSFDAILYYYQSGGRL+RPVNVP DIF+EE++FY+LGEEA
Sbjct: 63 KKRMRYFDPLRNEYFFDRNRPSFDAILYYYQSGGRLRRPVNVPLDIFSEEIRFYELGEEA 122
Query: 266 LLKFREDEGFVREEEDRALPENEFKKQIWLLFEYPESSSPARGIAIVSVLVILISIVIFC 325
+ FREDEG+++EEE R LPENEF++Q+WLLFEYPESS PAR IAIVSV+VILISIV FC
Sbjct: 123 MEMFREDEGYIKEEE-RPLPENEFQRQVWLLFEYPESSGPARIIAIVSVMVILISIVSFC 181
Query: 326 LETLPEFRDDRDLVMALSAGGHGGLLNDTSAPHLENSGHTIFNDPFFIVETVCIVWFSFE 385
LETLP FRD+ + G G + S + T F DPFFIVET+CI+WFSFE
Sbjct: 182 LETLPIFRDENE-----DMHGSGVTFHTYSNSTIGYQQSTSFTDPFFIVETLCIIWFSFE 236
Query: 386 FVVRCFACPSQALFFKNIMNIIDIVSILPYFITLGTDLAQQQGGGNGQQQQAMSFAILRI 445
F+VR FACPS+A FF NIMNIIDIV+I+PYFITLGT+LA++ Q QQAMS AILR+
Sbjct: 237 FLVRFFACPSKAGFFTNIMNIIDIVAIIPYFITLGTELAEKPEDAQ-QGQQAMSLAILRV 295
Query: 446 IRLVRVFRIFKLSRHSKGLQILGHTLRASMRELGLLIFFLFIGVILFSSAVYFAEADEPT 505
IRLVRVFRIFKLSRHSKGLQILG TL+ASMRELGLLIFFLFIGVILFSSAVYFAEADE
Sbjct: 296 IRLVRVFRIFKLSRHSKGLQILGQTLKASMRELGLLIFFLFIGVILFSSAVYFAEADERE 355
Query: 506 THFQSIPDAFWWAVVTMTTVGYGDMKPITVGGKIVGSLCAIAGVLTIALPVPVIVSNFNY 565
+ F SIPDAFWWAVV+MTTVGYGDM P T+GGKIVGSLCAIAGVLTIALPVPVIVSNFNY
Sbjct: 356 SQFPSIPDAFWWAVVSMTTVGYGDMVPTTIGGKIVGSLCAIAGVLTIALPVPVIVSNFNY 415
Query: 566 FYHRETENEEQTQLTQNAVSCPYLPSNL-LKKFRSSTSSSLGDKSEYLEMEEGVKES 621
FYHRETE EEQ Q Q SCP +PS+ LKK RS+++ S KS+Y+E++EGV S
Sbjct: 416 FYHRETEGEEQAQYLQ-VTSCPKIPSSPDLKKSRSASTIS---KSDYMEIQEGVNNS 468
>gi|25952087 potassium voltage-gated channel, shaker-related
subfamily, member 5 [Homo sapiens]
Length = 613
Score = 609 bits (1571), Expect = e-174
Identities = 321/473 (67%), Positives = 370/473 (78%), Gaps = 19/473 (4%)
Query: 176 ERVVINVSGLRFETQMKTLAQFPETLLGDPEKRTQYFDPLRNEYFFDRNRPSFDAILYYY 235
+RV IN+SGLRFETQ+ TLAQFP TLLGDP KR +YFDPLRNEYFFDRNRPSFD ILYYY
Sbjct: 120 QRVHINISGLRFETQLGTLAQFPNTLLGDPAKRLRYFDPLRNEYFFDRNRPSFDGILYYY 179
Query: 236 QSGGRLKRPVNVPFDIFTEEVKFYQLGEEALLKFREDEGFVREEEDRALPENEFKKQIWL 295
QSGGRL+RPVNV D+F +E++FYQLG+EA+ +FREDEGF++EEE + LP NEF++Q+WL
Sbjct: 180 QSGGRLRRPVNVSLDVFADEIRFYQLGDEAMERFREDEGFIKEEE-KPLPRNEFQRQVWL 238
Query: 296 LFEYPESSSPARGIAIVSVLVILISIVIFCLETLPEFRDDRDLVM---------ALSAGG 346
+FEYPESS AR IAIVSVLVILISI+ FCLETLPEFRD+R+L+ A + G
Sbjct: 239 IFEYPESSGSARAIAIVSVLVILISIITFCLETLPEFRDERELLRHPPAPHQPPAPAPGA 298
Query: 347 HG-GLLNDTSAPHLENSGHTIFNDPFFIVETVCIVWFSFEFVVRCFACPSQALFFKNIMN 405
+G G++ S P + DPFFIVET C++WF+FE +VR FACPS+A F +NIMN
Sbjct: 299 NGSGVMAPPSGPTVAPLLPRTLADPFFIVETTCVIWFTFELLVRFFACPSKAGFSRNIMN 358
Query: 406 IIDIVSILPYFITLGTDLAQQQ--GGGNGQQ-QQAMSFAILRIIRLVRVFRIFKLSRHSK 462
IID+V+I PYFITLGT+LA+QQ GGG GQ QQAMS AILR+IRLVRVFRIFKLSRHSK
Sbjct: 359 IIDVVAIFPYFITLGTELAEQQPGGGGGGQNGQQAMSLAILRVIRLVRVFRIFKLSRHSK 418
Query: 463 GLQILGHTLRASMRELGLLIFFLFIGVILFSSAVYFAEADEPTTHFQSIPDAFWWAVVTM 522
GLQILG TL+ASMRELGLLIFFLFIGVILFSSAVYFAEAD THF SIPDAFWWAVVTM
Sbjct: 419 GLQILGKTLQASMRELGLLIFFLFIGVILFSSAVYFAEADNQGTHFSSIPDAFWWAVVTM 478
Query: 523 TTVGYGDMKPITVGGKIVGSLCAIAGVLTIALPVPVIVSNFNYFYHRETENEEQTQLTQ- 581
TTVGYGDM+PITVGGKIVGSLCAIAGVLTIALPVPVIVSNFNYFYHRET++EE L +
Sbjct: 479 TTVGYGDMRPITVGGKIVGSLCAIAGVLTIALPVPVIVSNFNYFYHRETDHEEPAVLKEE 538
Query: 582 --NAVSCPYLPSNLLKKFRSSTSSSLGDKSEYLEMEEGVKESLCAKEEKCQGK 632
P L + +K S + S LE + + C EKC K
Sbjct: 539 QGTQSQGPGLDRGVQRKV-SGSRGSFCKAGGTLENADSARRGSCPL-EKCNVK 589
>gi|4504821 potassium voltage-gated channel, shaker-related
subfamily, member 6 [Homo sapiens]
Length = 529
Score = 602 bits (1551), Expect = e-172
Identities = 319/464 (68%), Positives = 360/464 (77%), Gaps = 45/464 (9%)
Query: 158 PQDEGGGGYSSVRYSDCC--ERVVINVSGLRFETQMKTLAQFPETLLGDPEKRTQYFDPL 215
P+ GGGG CC ER+VIN+SGLRFETQ++TL+ FP+TLLGDP +R ++FDPL
Sbjct: 29 PEAGGGGG--------CCSSERLVINISGLRFETQLRTLSLFPDTLLGDPGRRVRFFDPL 80
Query: 216 RNEYFFDRNRPSFDAILYYYQSGGRLKRPVNVPFDIFTEEVKFYQLGEEALLKFREDEGF 275
RNEYFFDRNRPSFDAILYYYQSGGRL+RPVNVP DIF EE++FYQLG+EAL FREDEG
Sbjct: 81 RNEYFFDRNRPSFDAILYYYQSGGRLRRPVNVPLDIFLEEIRFYQLGDEALAAFREDEGC 140
Query: 276 VRE--EEDRALPENEFKKQIWLLFEYPESSSPARGIAIVSVLVILISIVIFCLETLPEFR 333
+ E E+++ LP F++Q+WLLFEYPESS PARGIAIVSVLVILISIVIFCLETLP+FR
Sbjct: 141 LPEGGEDEKPLPSQPFQRQVWLLFEYPESSGPARGIAIVSVLVILISIVIFCLETLPQFR 200
Query: 334 DDR--------DLVMALSAGG--------------HG---GLLNDTSAPHLENSGHTIFN 368
D V +S G HG G + + L G + F
Sbjct: 201 VDGRGGNNGGVSRVSPVSRGSQEEEEDEDDSYTFHHGITPGEMGTGGSSSLSTLGGSFFT 260
Query: 369 DPFFIVETVCIVWFSFEFVVRCFACPSQALFFKNIMNIIDIVSILPYFITLGTDLAQQQ- 427
DPFF+VET+CIVWF+FE +VR ACPS+ FF+NIMNIID+V+I PYFITLGT+L QQQ
Sbjct: 261 DPFFLVETLCIVWFTFELLVRFSACPSKPAFFRNIMNIIDLVAIFPYFITLGTELVQQQE 320
Query: 428 -----GGGNGQQQQAMSFAILRIIRLVRVFRIFKLSRHSKGLQILGHTLRASMRELGLLI 482
GGG QQAMS AILR+IRLVRVFRIFKLSRHSKGLQILG TL+ASMRELGLLI
Sbjct: 321 QQPASGGGGQNGQQAMSLAILRVIRLVRVFRIFKLSRHSKGLQILGKTLQASMRELGLLI 380
Query: 483 FFLFIGVILFSSAVYFAEADEPTTHFQSIPDAFWWAVVTMTTVGYGDMKPITVGGKIVGS 542
FFLFIGVILFSSAVYFAEAD+ + F SIPDAFWWAVVTMTTVGYGDM P+TVGGKIVGS
Sbjct: 381 FFLFIGVILFSSAVYFAEADDDDSLFPSIPDAFWWAVVTMTTVGYGDMYPMTVGGKIVGS 440
Query: 543 LCAIAGVLTIALPVPVIVSNFNYFYHRETENEEQTQLTQNAVSC 586
LCAIAGVLTIALPVPVIVSNFNYFYHRETE EEQ Q T V+C
Sbjct: 441 LCAIAGVLTIALPVPVIVSNFNYFYHRETEQEEQGQYTH--VTC 482
>gi|5031819 potassium voltage-gated channel, shaker-related
subfamily, member 10 [Homo sapiens]
Length = 511
Score = 570 bits (1469), Expect = e-162
Identities = 285/408 (69%), Positives = 331/408 (81%), Gaps = 21/408 (5%)
Query: 176 ERVVINVSGLRFETQMKTLAQFPETLLGDPEKRTQYFDPLRNEYFFDRNRPSFDAILYYY 235
+RV+IN++GLRFETQ++TL+QFPETLLGD EKR Q+FD +RNEYFFDRNRPSFD ILYYY
Sbjct: 86 QRVIINIAGLRFETQLRTLSQFPETLLGDREKRMQFFDSMRNEYFFDRNRPSFDGILYYY 145
Query: 236 QSGGRLKRPVNVPFDIFTEEVKFYQLGEEALLKFREDEGFVREEEDRALPENEFKKQIWL 295
QSGG+++RP NVP DIF +E+ FY+LG EA+ +FREDEGF+++ E LP N+ +Q WL
Sbjct: 146 QSGGKIRRPANVPIDIFADEISFYELGSEAMDQFREDEGFIKDPET-LLPTNDIHRQFWL 204
Query: 296 LFEYPESSSPARGIAIVSVLVILISIVIFCLETLPEFRDDRDLVMALSAGGHGGLLNDTS 355
LFEYPESSS AR +A+VSVLV++ISI IFCLETLPEFR+DR+L +
Sbjct: 205 LFEYPESSSAARAVAVVSVLVVVISITIFCLETLPEFREDRELKVVRD------------ 252
Query: 356 APHLENS----GHTIFNDPFFIVETVCIVWFSFEFVVRCFACPSQALFFKNIMNIIDIVS 411
P+L S T+F DPFF+VE+ CIVWF+FE V+R CPS+ FF+NIMNIIDI+S
Sbjct: 253 -PNLNMSKTVLSQTMFTDPFFMVESTCIVWFTFELVLRFVVCPSKTDFFRNIMNIIDIIS 311
Query: 412 ILPYFITLGTDLAQQQGGGNGQQQQAMSFAILRIIRLVRVFRIFKLSRHSKGLQILGHTL 471
I+PYF TL T+L Q+ QQ MS AILRIIRLVRVFRIFKLSRHSKGLQILG TL
Sbjct: 312 IIPYFATLITELVQET---EPSAQQNMSLAILRIIRLVRVFRIFKLSRHSKGLQILGQTL 368
Query: 472 RASMRELGLLIFFLFIGVILFSSAVYFAEADEPTTHFQSIPDAFWWAVVTMTTVGYGDMK 531
+ASMRELGLLIFFLFIGVILFSSAVYFAE DEP +HF SIPD FWWAVVTMTTVGYGDM
Sbjct: 369 KASMRELGLLIFFLFIGVILFSSAVYFAEVDEPESHFSSIPDGFWWAVVTMTTVGYGDMC 428
Query: 532 PITVGGKIVGSLCAIAGVLTIALPVPVIVSNFNYFYHRETENEEQTQL 579
P T GGKIVG+LCAIAGVLTIALPVPVIVSNFNYFYHRETENEE+ +
Sbjct: 429 PTTPGGKIVGTLCAIAGVLTIALPVPVIVSNFNYFYHRETENEEKQNI 476
>gi|25952092 potassium voltage-gated channel, shaker-related
subfamily, member 7 [Homo sapiens]
Length = 456
Score = 569 bits (1466), Expect = e-162
Identities = 285/405 (70%), Positives = 332/405 (81%), Gaps = 9/405 (2%)
Query: 174 CCERVVINVSGLRFETQMKTLAQFPETLLGDPEKRTQYFDPLRNEYFFDRNRPSFDAILY 233
CCER+V+NV+GLRFET+ +TL +FP+TLLGDP +R +++D R EYFFDR+RPSFDA+LY
Sbjct: 11 CCERLVLNVAGLRFETRARTLGRFPDTLLGDPARRGRFYDDARREYFFDRHRPSFDAVLY 70
Query: 234 YYQSGGRLKRPVNVPFDIFTEEVKFYQLGEEALLKFREDEGFVREEEDRALPENEFKKQI 293
YYQSGGRL+RP +VP D+F EEV FY LG AL + REDEG E R LP F +Q+
Sbjct: 71 YYQSGGRLRRPAHVPLDVFLEEVAFYGLGAAALARLREDEGCPVPPE-RPLPRRAFARQL 129
Query: 294 WLLFEYPESSSPARGIAIVSVLVILISIVIFCLETLPEFRDDRD---LVMALSAGGHGGL 350
WLLFE+PESS AR +A+VSVLVIL+SIV+FCLETLP+FRDDRD L A +AG
Sbjct: 130 WLLFEFPESSQAARVLAVVSVLVILVSIVVFCLETLPDFRDDRDGTGLAAAAAAGPFPAP 189
Query: 351 LNDTSAPHLENSGHTIFNDPFFIVETVCIVWFSFEFVVRCFACPSQALFFKNIMNIIDIV 410
LN +S N FNDPFF+VET+CI WFSFE +VR CPS+A+FFKN+MN+ID V
Sbjct: 190 LNGSSQMP-GNPPRLPFNDPFFVVETLCICWFSFELLVRLLVCPSKAIFFKNVMNLIDFV 248
Query: 411 SILPYFITLGTDLAQQQGGGNGQQQQAMSFAILRIIRLVRVFRIFKLSRHSKGLQILGHT 470
+ILPYF+ LGT+LA+Q+G G QQAMS AILR+IRLVRVFRIFKLSRHSKGLQILG T
Sbjct: 249 AILPYFVALGTELARQRGVG----QQAMSLAILRVIRLVRVFRIFKLSRHSKGLQILGQT 304
Query: 471 LRASMRELGLLIFFLFIGVILFSSAVYFAEADEPTTHFQSIPDAFWWAVVTMTTVGYGDM 530
LRASMRELGLLIFFLFIGV+LFSSAVYFAE D +HF SIP++FWWAVVTMTTVGYGDM
Sbjct: 305 LRASMRELGLLIFFLFIGVVLFSSAVYFAEVDRVDSHFTSIPESFWWAVVTMTTVGYGDM 364
Query: 531 KPITVGGKIVGSLCAIAGVLTIALPVPVIVSNFNYFYHRETENEE 575
P+TVGGKIVGSLCAIAGVLTI+LPVPVIVSNF+YFYHRETE EE
Sbjct: 365 APVTVGGKIVGSLCAIAGVLTISLPVPVIVSNFSYFYHRETEGEE 409
>gi|27436974 potassium voltage-gated channel, Shab-related
subfamily, member 2 [Homo sapiens]
Length = 911
Score = 274 bits (701), Expect = 2e-73
Identities = 167/434 (38%), Positives = 241/434 (55%), Gaps = 56/434 (12%)
Query: 169 VRYSDCCERVVINVSGLRFETQMKTLAQFPETLLGDPEKRTQYFDPLR---------NEY 219
+R C RV INV GL E +TL + P T LG + L NEY
Sbjct: 28 IRSKTCSRRVKINVGGLNHEVLWRTLDRLPRTRLGKLRDCNTHESLLEVCDDYNLNENEY 87
Query: 220 FFDRNRPSFDAILYYYQSGG--RLKRPVNVPF----------DIFTE---EVKFYQLGEE 264
FFDR+ +F +IL +Y++G ++ + F +I+ E + +++Q E+
Sbjct: 88 FFDRHPGAFTSILNFYRTGKLHMMEEMCALSFGQELDYWGIDEIYLESCCQARYHQKKEQ 147
Query: 265 ALLKFREDEGFVREEEDRALPEN---EFKKQIWLLFEYPESSSPARGIAIVSVLVILISI 321
+ R + +RE E + +K++W L E P SS A+ +AIVS+L I++S
Sbjct: 148 MNEELRREAETMREREGEEFDNTCCPDKRKKLWDLLEKPNSSVAAKILAIVSILFIVLST 207
Query: 322 VIFCLETLPEFRDDRDLVMALSAGGHGGLLNDTSAPHLENSGHTIFNDPFFIVETVCIVW 381
+ L TLPE ++ + G LND N VE VCI W
Sbjct: 208 IALSLNTLPELQETDEF----------GQLND--------------NRQLAHVEAVCIAW 243
Query: 382 FSFEFVVRCFACPSQALFFKNIMNIIDIVSILPYFITLGTDLAQQQGGGNGQQQQAMSFA 441
F+ E+++R + P++ FFK +N+ID+++ILPY++T+ + Q Q
Sbjct: 244 FTMEYLLRFLSSPNKWKFFKGPLNVIDLLAILPYYVTI---FLTESNKSVLQFQNVRR-- 298
Query: 442 ILRIIRLVRVFRIFKLSRHSKGLQILGHTLRASMRELGLLIFFLFIGVILFSSAVYFAEA 501
+++I R++R+ RI KL+RHS GLQ LG TLR S ELGLLI FL +G+++FSS V+FAE
Sbjct: 299 VVQIFRIMRILRILKLARHSTGLQSLGFTLRRSYNELGLLILFLAMGIMIFSSLVFFAEK 358
Query: 502 DEPTTHFQSIPDAFWWAVVTMTTVGYGDMKPITVGGKIVGSLCAIAGVLTIALPVPVIVS 561
DE T F SIP +FWWA +TMTTVGYGD+ P T+ GKIVG LC IAGVL IALP+P+IV+
Sbjct: 359 DEDATKFTSIPASFWWATITMTTVGYGDIYPKTLLGKIVGGLCCIAGVLVIALPIPIIVN 418
Query: 562 NFNYFYHRETENEE 575
NF+ FY + E+
Sbjct: 419 NFSEFYKEQKRQEK 432
>gi|4826786 Shaw-related voltage-gated potassium channel protein 1
isoform B [Homo sapiens]
Length = 511
Score = 273 bits (697), Expect = 5e-73
Identities = 176/462 (38%), Positives = 252/462 (54%), Gaps = 90/462 (19%)
Query: 173 DCCERVVINVSGLRFETQMKTLAQFPETLLG---DPEKRTQY-FDPLRNEYFFDRNRPSF 228
D ER+VINV G R +T TL P T L +P+ + + +DP +E+FFDR+ F
Sbjct: 5 DESERIVINVGGTRHQTYRSTLRTLPGTRLAWLAEPDAHSHFDYDPRADEFFFDRHPGVF 64
Query: 229 DAILYYYQSGGRLKRPVNVPFDIFTEEVKFYQL------------------GEEALLKF- 269
IL YY++G +L P +V ++ EE+ F+ + EEAL F
Sbjct: 65 AHILNYYRTG-KLHCPADVCGPLYEEELAFWGIDETDVEPCCWMTYRQHRDAEEALDSFG 123
Query: 270 ------------REDEGFVREEEDR-------ALPEN----------EFKKQIWLLFEYP 300
+ G + ED AL ++ ++ +IW LFE P
Sbjct: 124 GAPLDNSADDADADGPGDSGDGEDELEMTKRLALSDSPDGRPGGFWRRWQPRIWALFEDP 183
Query: 301 ESSSPARGIAIVSVLVILISIVIFCLETLPEFRDDRDLVMALSAGGHGGLLNDTSAPHLE 360
SS AR +A S+ IL+SI FCLET F ++N T ++
Sbjct: 184 YSSRYARYVAFASLFFILVSITTFCLETHERFNP---------------IVNKTEIENVR 228
Query: 361 NSGHTIF-----NDPFFI-VETVCIVWFSFEFVVRCFACPSQALFFKNIMNIIDIVSILP 414
N + + F +E VC+VWF+FEF++R CP++ F KN +NIID V+ILP
Sbjct: 229 NGTQVRYYREAETEAFLTYIEGVCVVWFTFEFLMRVIFCPNKVEFIKNSLNIIDFVAILP 288
Query: 415 YFITLGTDLAQQQGGGNGQQQQAMSFAILRIIRLVRVFRIFKLSRHSKGLQILGHTLRAS 474
+++ +G G + + + F LR++R VR+ RIFKL+RH GL++LGHTLRAS
Sbjct: 289 FYLEVGLS-----GLSSKAAKDVLGF--LRVVRFVRILRIFKLTRHFVGLRVLGHTLRAS 341
Query: 475 MRELGLLIFFLFIGVILFSSAVYFAEA-----DEPT----THFQSIPDAFWWAVVTMTTV 525
E LLI FL +GV++F++ +Y+AE ++P+ THF++IP FWWAVVTMTT+
Sbjct: 342 TNEFLLLIIFLALGVLIFATMIYYAERIGAQPNDPSASEHTHFKNIPIGFWWAVVTMTTL 401
Query: 526 GYGDMKPITVGGKIVGSLCAIAGVLTIALPVPVIVSNFNYFY 567
GYGDM P T G +VG+LCA+AGVLTIA+PVPVIV+NF +Y
Sbjct: 402 GYGDMYPQTWSGMLVGALCALAGVLTIAMPVPVIVNNFGMYY 443
>gi|163792201 Shaw-related voltage-gated potassium channel protein 1
isoform A [Homo sapiens]
Length = 585
Score = 273 bits (697), Expect = 5e-73
Identities = 176/462 (38%), Positives = 252/462 (54%), Gaps = 90/462 (19%)
Query: 173 DCCERVVINVSGLRFETQMKTLAQFPETLLG---DPEKRTQY-FDPLRNEYFFDRNRPSF 228
D ER+VINV G R +T TL P T L +P+ + + +DP +E+FFDR+ F
Sbjct: 5 DESERIVINVGGTRHQTYRSTLRTLPGTRLAWLAEPDAHSHFDYDPRADEFFFDRHPGVF 64
Query: 229 DAILYYYQSGGRLKRPVNVPFDIFTEEVKFYQL------------------GEEALLKF- 269
IL YY++G +L P +V ++ EE+ F+ + EEAL F
Sbjct: 65 AHILNYYRTG-KLHCPADVCGPLYEEELAFWGIDETDVEPCCWMTYRQHRDAEEALDSFG 123
Query: 270 ------------REDEGFVREEEDR-------ALPEN----------EFKKQIWLLFEYP 300
+ G + ED AL ++ ++ +IW LFE P
Sbjct: 124 GAPLDNSADDADADGPGDSGDGEDELEMTKRLALSDSPDGRPGGFWRRWQPRIWALFEDP 183
Query: 301 ESSSPARGIAIVSVLVILISIVIFCLETLPEFRDDRDLVMALSAGGHGGLLNDTSAPHLE 360
SS AR +A S+ IL+SI FCLET F ++N T ++
Sbjct: 184 YSSRYARYVAFASLFFILVSITTFCLETHERFNP---------------IVNKTEIENVR 228
Query: 361 NSGHTIF-----NDPFFI-VETVCIVWFSFEFVVRCFACPSQALFFKNIMNIIDIVSILP 414
N + + F +E VC+VWF+FEF++R CP++ F KN +NIID V+ILP
Sbjct: 229 NGTQVRYYREAETEAFLTYIEGVCVVWFTFEFLMRVIFCPNKVEFIKNSLNIIDFVAILP 288
Query: 415 YFITLGTDLAQQQGGGNGQQQQAMSFAILRIIRLVRVFRIFKLSRHSKGLQILGHTLRAS 474
+++ +G G + + + F LR++R VR+ RIFKL+RH GL++LGHTLRAS
Sbjct: 289 FYLEVGLS-----GLSSKAAKDVLGF--LRVVRFVRILRIFKLTRHFVGLRVLGHTLRAS 341
Query: 475 MRELGLLIFFLFIGVILFSSAVYFAEA-----DEPT----THFQSIPDAFWWAVVTMTTV 525
E LLI FL +GV++F++ +Y+AE ++P+ THF++IP FWWAVVTMTT+
Sbjct: 342 TNEFLLLIIFLALGVLIFATMIYYAERIGAQPNDPSASEHTHFKNIPIGFWWAVVTMTTL 401
Query: 526 GYGDMKPITVGGKIVGSLCAIAGVLTIALPVPVIVSNFNYFY 567
GYGDM P T G +VG+LCA+AGVLTIA+PVPVIV+NF +Y
Sbjct: 402 GYGDMYPQTWSGMLVGALCALAGVLTIAMPVPVIVNNFGMYY 443
>gi|4826784 potassium voltage-gated channel, Shab-related subfamily,
member 1 [Homo sapiens]
Length = 858
Score = 270 bits (689), Expect = 4e-72
Identities = 164/435 (37%), Positives = 237/435 (54%), Gaps = 58/435 (13%)
Query: 169 VRYSDCCERVVINVSGLRFETQMKTLAQFPETLLGDPEKRTQYFDPLR---------NEY 219
VR C RV +NV GL E +TL + P T LG + L NEY
Sbjct: 24 VRSKACSRRVRLNVGGLAHEVLWRTLDRLPRTRLGKLRDCNTHDSLLEVCDDYSLDDNEY 83
Query: 220 FFDRNRPSFDAILYYYQSGGRLKRPVNVPFDIFTEEV----------------KFYQLGE 263
FFDR+ +F +IL +Y++G RL + F++E+ +++Q E
Sbjct: 84 FFDRHPGAFTSILNFYRTG-RLHMMEEMCALSFSQELDYWGIDEIYLESCCQARYHQKKE 142
Query: 264 EALLKFREDEGFVREEEDRALPEN---EFKKQIWLLFEYPESSSPARGIAIVSVLVILIS 320
+ + + + +RE E E +K++W L E P SS A+ +AI+S++ I++S
Sbjct: 143 QMNEELKREAETLREREGEEFDNTCCAEKRKKLWDLLEKPNSSVAAKILAIISIMFIVLS 202
Query: 321 IVIFCLETLPEFRDDRDLVMALSAGGHGGLLNDTSAPHLENSGHTIFNDPFFIVETVCIV 380
+ L TLPE + L+ G + N VE VCI
Sbjct: 203 TIALSLNTLPELQS------------------------LDEFGQSTDNPQLAHVEAVCIA 238
Query: 381 WFSFEFVVRCFACPSQALFFKNIMNIIDIVSILPYFITLGTDLAQQQGGGNGQQQQAMSF 440
WF+ E+++R + P + FFK +N ID+++ILPY++T+ + Q Q
Sbjct: 239 WFTMEYLLRFLSSPKKWKFFKGPLNAIDLLAILPYYVTI---FLTESNKSVLQFQNVRR- 294
Query: 441 AILRIIRLVRVFRIFKLSRHSKGLQILGHTLRASMRELGLLIFFLFIGVILFSSAVYFAE 500
+++I R++R+ RI KL+RHS GLQ LG TLR S ELGLLI FL +G+++FSS V+FAE
Sbjct: 295 -VVQIFRIMRILRILKLARHSTGLQSLGFTLRRSYNELGLLILFLAMGIMIFSSLVFFAE 353
Query: 501 ADEPTTHFQSIPDAFWWAVVTMTTVGYGDMKPITVGGKIVGSLCAIAGVLTIALPVPVIV 560
DE T F+SIP +FWWA +TMTTVGYGD+ P T+ GKIVG LC IAGVL IALP+P+IV
Sbjct: 354 KDEDDTKFKSIPASFWWATITMTTVGYGDIYPKTLLGKIVGGLCCIAGVLVIALPIPIIV 413
Query: 561 SNFNYFYHRETENEE 575
+NF+ FY + E+
Sbjct: 414 NNFSEFYKEQKRQEK 428
>gi|27436981 potassium voltage-gated channel, Shal-related
subfamily, member 1 [Homo sapiens]
Length = 647
Score = 266 bits (679), Expect = 6e-71
Identities = 160/418 (38%), Positives = 238/418 (56%), Gaps = 50/418 (11%)
Query: 176 ERVVINVSGLRFETQMKTLAQFPETLLGDPEKRTQYFDPLRNEYFFDRNRPSFDAILYYY 235
E +V+NVSG RFET TL ++P+TLLG EK ++D EYFFDR+ F +L +Y
Sbjct: 40 EVLVVNVSGRRFETWKNTLDRYPDTLLGSSEKEF-FYDADSGEYFFDRDPDMFRHVLNFY 98
Query: 236 QSGGRLKRPVNVPFDIFTEEVKFYQL-----GEEALLKFR-----------EDEGFVREE 279
++G RL P F EE+ FY L G+ L ++R EDE +
Sbjct: 99 RTG-RLHCPRQECIQAFDEELAFYGLVPELVGDCCLEEYRDRKKENAERLAEDEEAEQAG 157
Query: 280 EDRALPE-NEFKKQIWLLFEYPESSSPARGIAIVSVLVILISIVIFCLETLPEFRDDRDL 338
+ ALP + ++++W FE P +S+ A V+ I +S++ +ET+P R
Sbjct: 158 DGPALPAGSSLRQRLWRAFENPHTSTAALVFYYVTGFFIAVSVIANVVETIPCRGSARRS 217
Query: 339 VMALSAGGHGGLLNDTSAPHLENSGHTIFNDPFFIVETVCIVWFSFEFVVRCFACPSQAL 398
G F FF ++T C++ F+ E+++R FA PS+
Sbjct: 218 SREQPCGER-------------------FPQAFFCMDTACVLIFTGEYLLRLFAAPSRCR 258
Query: 399 FFKNIMNIIDIVSILPYFITLGTDLAQQQGGGNGQQQQAMSFAILRIIRLVRVFRIFKLS 458
F +++M++ID+V+ILPY+I L G +F LR+ R VFRIFK S
Sbjct: 259 FLRSVMSLIDVVAILPYYIGLLVPKNDDVSG---------AFVTLRVFR---VFRIFKFS 306
Query: 459 RHSKGLQILGHTLRASMRELGLLIFFLFIGVILFSSAVYFAEADEPTTHFQSIPDAFWWA 518
RHS+GL+ILG+TL++ ELG L+F L + +I+F++ +++AE T+F SIP AFW+
Sbjct: 307 RHSQGLRILGYTLKSCASELGFLLFSLTMAIIIFATVMFYAEKGTNKTNFTSIPAAFWYT 366
Query: 519 VVTMTTVGYGDMKPITVGGKIVGSLCAIAGVLTIALPVPVIVSNFNYFYHRETENEEQ 576
+VTMTT+GYGDM P T+ GKI GS+C+++GVL IALPVPVIVSNF+ YH+ +++
Sbjct: 367 IVTMTTLGYGDMVPSTIAGKIFGSICSLSGVLVIALPVPVIVSNFSRIYHQNQRADKR 424
>gi|88758576 Shaw-related voltage-gated potassium channel protein 4
isoform c [Homo sapiens]
Length = 626
Score = 260 bits (665), Expect = 2e-69
Identities = 176/465 (37%), Positives = 243/465 (52%), Gaps = 88/465 (18%)
Query: 173 DCCERVVINVSGLRFETQMKTLAQFPETLL---------GDPEKRTQYFDPLRN------ 217
+ E+++INV G R ET TL P T L G PE +
Sbjct: 33 EASEKIIINVGGTRHETYRSTLRTLPGTRLAWLADPDGGGRPETDGGGVGSSGSSGGGGC 92
Query: 218 EYFFDRNRPSFDAILYYYQSGGRLKRPVNVPFDIFTEEVKFYQL---------------- 261
E+FFDR+ F +L YY++G +L P +V +F EE+ F+ +
Sbjct: 93 EFFFDRHPGVFAYVLNYYRTG-KLHCPADVCGPLFEEELTFWGIDETDVEPCCWMTYRQH 151
Query: 262 --GEEALLKFREDEGFVR----------EEEDRALPE-----------------NEFKKQ 292
EEAL F +G +E + AL ++ +
Sbjct: 152 RDAEEALDIFESPDGGGSGAGPSDEAGDDERELALQRLGPHEGGAGHGAGSGGCRGWQPR 211
Query: 293 IWLLFEYPESSSPARGIAIVSVLVILISIVIFCLETLPEFRDDRDLVMALSAGGHGGLLN 352
+W LFE P SS AR +A S+ IL+SI FCLET F DR++ L G N
Sbjct: 212 MWALFEDPYSSRAARVVAFASLFFILVSITTFCLETHEAFNIDRNVTEILRVG------N 265
Query: 353 DTSAPHLENSGHTIFNDPFFI-VETVCIVWFSFEFVVRCFACPSQALFFKNIMNIIDIVS 411
TS H T +P +E VC++WF+ EF+VR CP F KN++NIID V+
Sbjct: 266 ITSV-HFRREVET---EPILTYIEGVCVLWFTLEFLVRIVCCPDTLDFVKNLLNIIDFVA 321
Query: 412 ILPYFITLGTDLAQQQGGGNGQQQQAMSFAILRIIRLVRVFRIFKLSRHSKGLQILGHTL 471
ILP+++ +G G + + + F LR++R VR+ RIFKL+RH GL++LGHTL
Sbjct: 322 ILPFYLEVGLS-----GLSSKAARDVLGF--LRVVRFVRILRIFKLTRHFVGLRVLGHTL 374
Query: 472 RASMRELGLLIFFLFIGVILFSSAVYFAEA-----DEPT----THFQSIPDAFWWAVVTM 522
RAS E LLI FL +GV++F++ +Y+AE +P T F++IP FWWAVVTM
Sbjct: 375 RASTNEFLLLIIFLALGVLIFATMIYYAERIGARPSDPRGNDHTDFKNIPIGFWWAVVTM 434
Query: 523 TTVGYGDMKPITVGGKIVGSLCAIAGVLTIALPVPVIVSNFNYFY 567
TT+GYGDM P T G +VG+LCA+AGVLTIA+PVPVIV+NF +Y
Sbjct: 435 TTLGYGDMYPKTWSGMLVGALCALAGVLTIAMPVPVIVNNFGMYY 479
>gi|24497462 Shaw-related voltage-gated potassium channel protein 4
isoform a [Homo sapiens]
Length = 635
Score = 260 bits (665), Expect = 2e-69
Identities = 176/465 (37%), Positives = 243/465 (52%), Gaps = 88/465 (18%)
Query: 173 DCCERVVINVSGLRFETQMKTLAQFPETLL---------GDPEKRTQYFDPLRN------ 217
+ E+++INV G R ET TL P T L G PE +
Sbjct: 33 EASEKIIINVGGTRHETYRSTLRTLPGTRLAWLADPDGGGRPETDGGGVGSSGSSGGGGC 92
Query: 218 EYFFDRNRPSFDAILYYYQSGGRLKRPVNVPFDIFTEEVKFYQL---------------- 261
E+FFDR+ F +L YY++G +L P +V +F EE+ F+ +
Sbjct: 93 EFFFDRHPGVFAYVLNYYRTG-KLHCPADVCGPLFEEELTFWGIDETDVEPCCWMTYRQH 151
Query: 262 --GEEALLKFREDEGFVR----------EEEDRALPE-----------------NEFKKQ 292
EEAL F +G +E + AL ++ +
Sbjct: 152 RDAEEALDIFESPDGGGSGAGPSDEAGDDERELALQRLGPHEGGAGHGAGSGGCRGWQPR 211
Query: 293 IWLLFEYPESSSPARGIAIVSVLVILISIVIFCLETLPEFRDDRDLVMALSAGGHGGLLN 352
+W LFE P SS AR +A S+ IL+SI FCLET F DR++ L G N
Sbjct: 212 MWALFEDPYSSRAARVVAFASLFFILVSITTFCLETHEAFNIDRNVTEILRVG------N 265
Query: 353 DTSAPHLENSGHTIFNDPFFI-VETVCIVWFSFEFVVRCFACPSQALFFKNIMNIIDIVS 411
TS H T +P +E VC++WF+ EF+VR CP F KN++NIID V+
Sbjct: 266 ITSV-HFRREVET---EPILTYIEGVCVLWFTLEFLVRIVCCPDTLDFVKNLLNIIDFVA 321
Query: 412 ILPYFITLGTDLAQQQGGGNGQQQQAMSFAILRIIRLVRVFRIFKLSRHSKGLQILGHTL 471
ILP+++ +G G + + + F LR++R VR+ RIFKL+RH GL++LGHTL
Sbjct: 322 ILPFYLEVGLS-----GLSSKAARDVLGF--LRVVRFVRILRIFKLTRHFVGLRVLGHTL 374
Query: 472 RASMRELGLLIFFLFIGVILFSSAVYFAEA-----DEPT----THFQSIPDAFWWAVVTM 522
RAS E LLI FL +GV++F++ +Y+AE +P T F++IP FWWAVVTM
Sbjct: 375 RASTNEFLLLIIFLALGVLIFATMIYYAERIGARPSDPRGNDHTDFKNIPIGFWWAVVTM 434
Query: 523 TTVGYGDMKPITVGGKIVGSLCAIAGVLTIALPVPVIVSNFNYFY 567
TT+GYGDM P T G +VG+LCA+AGVLTIA+PVPVIV+NF +Y
Sbjct: 435 TTLGYGDMYPKTWSGMLVGALCALAGVLTIAMPVPVIVNNFGMYY 479
>gi|24497464 Shaw-related voltage-gated potassium channel protein 4
isoform b [Homo sapiens]
Length = 582
Score = 260 bits (665), Expect = 2e-69
Identities = 176/465 (37%), Positives = 243/465 (52%), Gaps = 88/465 (18%)
Query: 173 DCCERVVINVSGLRFETQMKTLAQFPETLL---------GDPEKRTQYFDPLRN------ 217
+ E+++INV G R ET TL P T L G PE +
Sbjct: 33 EASEKIIINVGGTRHETYRSTLRTLPGTRLAWLADPDGGGRPETDGGGVGSSGSSGGGGC 92
Query: 218 EYFFDRNRPSFDAILYYYQSGGRLKRPVNVPFDIFTEEVKFYQL---------------- 261
E+FFDR+ F +L YY++G +L P +V +F EE+ F+ +
Sbjct: 93 EFFFDRHPGVFAYVLNYYRTG-KLHCPADVCGPLFEEELTFWGIDETDVEPCCWMTYRQH 151
Query: 262 --GEEALLKFREDEGFVR----------EEEDRALPE-----------------NEFKKQ 292
EEAL F +G +E + AL ++ +
Sbjct: 152 RDAEEALDIFESPDGGGSGAGPSDEAGDDERELALQRLGPHEGGAGHGAGSGGCRGWQPR 211
Query: 293 IWLLFEYPESSSPARGIAIVSVLVILISIVIFCLETLPEFRDDRDLVMALSAGGHGGLLN 352
+W LFE P SS AR +A S+ IL+SI FCLET F DR++ L G N
Sbjct: 212 MWALFEDPYSSRAARVVAFASLFFILVSITTFCLETHEAFNIDRNVTEILRVG------N 265
Query: 353 DTSAPHLENSGHTIFNDPFFI-VETVCIVWFSFEFVVRCFACPSQALFFKNIMNIIDIVS 411
TS H T +P +E VC++WF+ EF+VR CP F KN++NIID V+
Sbjct: 266 ITSV-HFRREVET---EPILTYIEGVCVLWFTLEFLVRIVCCPDTLDFVKNLLNIIDFVA 321
Query: 412 ILPYFITLGTDLAQQQGGGNGQQQQAMSFAILRIIRLVRVFRIFKLSRHSKGLQILGHTL 471
ILP+++ +G G + + + F LR++R VR+ RIFKL+RH GL++LGHTL
Sbjct: 322 ILPFYLEVGLS-----GLSSKAARDVLGF--LRVVRFVRILRIFKLTRHFVGLRVLGHTL 374
Query: 472 RASMRELGLLIFFLFIGVILFSSAVYFAEA-----DEPT----THFQSIPDAFWWAVVTM 522
RAS E LLI FL +GV++F++ +Y+AE +P T F++IP FWWAVVTM
Sbjct: 375 RASTNEFLLLIIFLALGVLIFATMIYYAERIGARPSDPRGNDHTDFKNIPIGFWWAVVTM 434
Query: 523 TTVGYGDMKPITVGGKIVGSLCAIAGVLTIALPVPVIVSNFNYFY 567
TT+GYGDM P T G +VG+LCA+AGVLTIA+PVPVIV+NF +Y
Sbjct: 435 TTLGYGDMYPKTWSGMLVGALCALAGVLTIAMPVPVIVNNFGMYY 479
>gi|27436984 potassium voltage-gated channel, Shal-related
subfamily, member 3 isoform 1 [Homo sapiens]
Length = 655
Score = 258 bits (660), Expect = 9e-69
Identities = 152/415 (36%), Positives = 237/415 (57%), Gaps = 49/415 (11%)
Query: 176 ERVVINVSGLRFETQMKTLAQFPETLLGDPEKRTQYFDPLRNEYFFDRNRPSFDAILYYY 235
E +V+NVSG RF+T TL ++P+TLLG EK +F+ EYFFDR+ F +L +Y
Sbjct: 40 ELIVLNVSGRRFQTWRTTLERYPDTLLGSTEKEF-FFNEDTKEYFFDRDPEVFRCVLNFY 98
Query: 236 QSGGRLKRPVNVPFDIFTEEVKFYQLGEEAL-------LKFREDEGFVR-------EEED 281
++G +L P + +E+ FY + E + K R+ E R E
Sbjct: 99 RTG-KLHYPRYECISAYDDELAFYGILPEIIGDCCYEEYKDRKRENAERLMDDNDSENNQ 157
Query: 282 RALPENEFKKQIWLLFEYPESSSPARGIAIVSVLVILISIVIFCLETLPEFRDDRDLVMA 341
++P F++ +W FE P +S+ A V+ I +S++ +ET+P
Sbjct: 158 ESMPSLSFRQTMWRAFENPHTSTLALVFYYVTGFFIAVSVITNVVETVP----------- 206
Query: 342 LSAGGHGGLLNDTSAPHLENSGHTIFNDPFFIVETVCIVWFSFEFVVRCFACPSQALFFK 401
G + P E ++ FF ++T C++ F+ E+++R FA PS+ F +
Sbjct: 207 -----CGTVPGSKELPCGER-----YSVAFFCLDTACVMIFTVEYLLRLFAAPSRYRFIR 256
Query: 402 NIMNIIDIVSILPYFITLGTDLAQQQGGGNGQQQQAMSFAILRIIRLVRVFRIFKLSRHS 461
++M+IID+V+I+PY+I L + G +F LR+ R VFRIFK SRHS
Sbjct: 257 SVMSIIDVVAIMPYYIGLVMTNNEDVSG---------AFVTLRVFR---VFRIFKFSRHS 304
Query: 462 KGLQILGHTLRASMRELGLLIFFLFIGVILFSSAVYFAEADEPTTHFQSIPDAFWWAVVT 521
+GL+ILG+TL++ ELG L+F L + +I+F++ +++AE + F SIP +FW+ +VT
Sbjct: 305 QGLRILGYTLKSCASELGFLLFSLTMAIIIFATVMFYAEKGSSASKFTSIPASFWYTIVT 364
Query: 522 MTTVGYGDMKPITVGGKIVGSLCAIAGVLTIALPVPVIVSNFNYFYHRETENEEQ 576
MTT+GYGDM P T+ GKI GS+C+++GVL IALPVPVIVSNF+ YH+ +++
Sbjct: 365 MTTLGYGDMVPKTIAGKIFGSICSLSGVLVIALPVPVIVSNFSRIYHQNQRADKR 419
>gi|27436986 potassium voltage-gated channel, Shal-related
subfamily, member 3 isoform 2 [Homo sapiens]
Length = 636
Score = 258 bits (660), Expect = 9e-69
Identities = 152/415 (36%), Positives = 237/415 (57%), Gaps = 49/415 (11%)
Query: 176 ERVVINVSGLRFETQMKTLAQFPETLLGDPEKRTQYFDPLRNEYFFDRNRPSFDAILYYY 235
E +V+NVSG RF+T TL ++P+TLLG EK +F+ EYFFDR+ F +L +Y
Sbjct: 40 ELIVLNVSGRRFQTWRTTLERYPDTLLGSTEKEF-FFNEDTKEYFFDRDPEVFRCVLNFY 98
Query: 236 QSGGRLKRPVNVPFDIFTEEVKFYQLGEEAL-------LKFREDEGFVR-------EEED 281
++G +L P + +E+ FY + E + K R+ E R E
Sbjct: 99 RTG-KLHYPRYECISAYDDELAFYGILPEIIGDCCYEEYKDRKRENAERLMDDNDSENNQ 157
Query: 282 RALPENEFKKQIWLLFEYPESSSPARGIAIVSVLVILISIVIFCLETLPEFRDDRDLVMA 341
++P F++ +W FE P +S+ A V+ I +S++ +ET+P
Sbjct: 158 ESMPSLSFRQTMWRAFENPHTSTLALVFYYVTGFFIAVSVITNVVETVP----------- 206
Query: 342 LSAGGHGGLLNDTSAPHLENSGHTIFNDPFFIVETVCIVWFSFEFVVRCFACPSQALFFK 401
G + P E ++ FF ++T C++ F+ E+++R FA PS+ F +
Sbjct: 207 -----CGTVPGSKELPCGER-----YSVAFFCLDTACVMIFTVEYLLRLFAAPSRYRFIR 256
Query: 402 NIMNIIDIVSILPYFITLGTDLAQQQGGGNGQQQQAMSFAILRIIRLVRVFRIFKLSRHS 461
++M+IID+V+I+PY+I L + G +F LR+ R VFRIFK SRHS
Sbjct: 257 SVMSIIDVVAIMPYYIGLVMTNNEDVSG---------AFVTLRVFR---VFRIFKFSRHS 304
Query: 462 KGLQILGHTLRASMRELGLLIFFLFIGVILFSSAVYFAEADEPTTHFQSIPDAFWWAVVT 521
+GL+ILG+TL++ ELG L+F L + +I+F++ +++AE + F SIP +FW+ +VT
Sbjct: 305 QGLRILGYTLKSCASELGFLLFSLTMAIIIFATVMFYAEKGSSASKFTSIPASFWYTIVT 364
Query: 522 MTTVGYGDMKPITVGGKIVGSLCAIAGVLTIALPVPVIVSNFNYFYHRETENEEQ 576
MTT+GYGDM P T+ GKI GS+C+++GVL IALPVPVIVSNF+ YH+ +++
Sbjct: 365 MTTLGYGDMVPKTIAGKIFGSICSLSGVLVIALPVPVIVSNFSRIYHQNQRADKR 419
>gi|9789987 potassium voltage-gated channel, Shal-related subfamily,
member 2 [Homo sapiens]
Length = 630
Score = 257 bits (656), Expect = 3e-68
Identities = 153/414 (36%), Positives = 236/414 (57%), Gaps = 49/414 (11%)
Query: 178 VVINVSGLRFETQMKTLAQFPETLLGDPEKRTQYFDPLRNEYFFDRNRPSFDAILYYYQS 237
+V+NVSG RF+T TL ++P+TLLG E R ++ P +YFFDR+ F IL +Y++
Sbjct: 43 IVLNVSGTRFQTWQDTLERYPDTLLGSSE-RDFFYHPETQQYFFDRDPDIFRHILNFYRT 101
Query: 238 GGRLKRPVNVPFDIFTEEVKFYQLGEEAL-------LKFREDEGFVREEEDR-------- 282
G +L P + + EE+ F+ L E + K R E R ++D
Sbjct: 102 G-KLHYPRHECISAYDEELAFFGLIPEIIGDCCYEEYKDRRRENAERLQDDADTDTAGES 160
Query: 283 ALPENEFKKQIWLLFEYPESSSPARGIAIVSVLVILISIVIFCLETLPEFRDDRDLVMAL 342
ALP ++++W FE P +S+ A V+ I +S++ +ET+P
Sbjct: 161 ALPTMTARQRVWRAFENPHTSTMALVFYYVTGFFIAVSVIANVVETVP------------ 208
Query: 343 SAGGHGGLLNDTSAPHLENSGHTIFNDPFFIVETVCIVWFSFEFVVRCFACPSQALFFKN 402
G G + + + FF ++T C++ F+ E+++R A PS+ F ++
Sbjct: 209 -CGSSPGHIKELPCGER-------YAVAFFCLDTACVMIFTVEYLLRLAAAPSRYRFVRS 260
Query: 403 IMNIIDIVSILPYFITLGTDLAQQQGGGNGQQQQAMSFAILRIIRLVRVFRIFKLSRHSK 462
+M+IID+V+ILPY+I L + G +F LR+ R VFRIFK SRHS+
Sbjct: 261 VMSIIDVVAILPYYIGLVMTDNEDVSG---------AFVTLRVFR---VFRIFKFSRHSQ 308
Query: 463 GLQILGHTLRASMRELGLLIFFLFIGVILFSSAVYFAEADEPTTHFQSIPDAFWWAVVTM 522
GL+ILG+TL++ ELG L+F L + +I+F++ +++AE + F SIP AFW+ +VTM
Sbjct: 309 GLRILGYTLKSCASELGFLLFSLTMAIIIFATVMFYAEKGSSASKFTSIPAAFWYTIVTM 368
Query: 523 TTVGYGDMKPITVGGKIVGSLCAIAGVLTIALPVPVIVSNFNYFYHRETENEEQ 576
TT+GYGDM P T+ GKI GS+C+++GVL IALPVPVIVSNF+ YH+ +++
Sbjct: 369 TTLGYGDMVPKTIAGKIFGSICSLSGVLVIALPVPVIVSNFSRIYHQNQRADKR 422
>gi|21217561 Shaw-related voltage-gated potassium channel protein 2
isoform KV3.2a [Homo sapiens]
Length = 613
Score = 247 bits (630), Expect = 3e-65
Identities = 159/400 (39%), Positives = 223/400 (55%), Gaps = 70/400 (17%)
Query: 218 EYFFDRNRPSFDAILYYYQSGGRLKRPVNVPFDIFTEEVKFYQL---------------- 261
E+FFDR+ F +L YY++G +L P +V +F EE+ F+ +
Sbjct: 101 EFFFDRHPGVFAYVLNYYRTG-KLHCPADVCGPLFEEELAFWGIDETDVEPCCWMTYRQH 159
Query: 262 --GEEALLKFREDE---GFVREEEDRALPE-------------------NEFKKQIWLLF 297
EEAL F + G ++ED A + ++W LF
Sbjct: 160 RDAEEALDIFETPDLIGGDPGDDEDLAAKRLGIEDAAGLGGPDGKSGRWRRLQPRMWALF 219
Query: 298 EYPESSSPARGIAIVSVLVILISIVIFCLETLPEFRDDRDLVMALSAGGHGGLLNDTSAP 357
E P SS AR IA S+ IL+SI FCLET F ++ + +N TS
Sbjct: 220 EDPYSSRAARFIAFASLFFILVSITTFCLETHEAFNIVKNKTEPV--------INGTSVV 271
Query: 358 HLENSGHTIFNDPFFI-VETVCIVWFSFEFVVRCFACPSQALFFKNIMNIIDIVSILPYF 416
+ I DP VE VC+VWF+FEF+VR P++ F KN++NIID V+ILP++
Sbjct: 272 ----LQYEIETDPALTYVEGVCVVWFTFEFLVRIVFSPNKLEFIKNLLNIIDFVAILPFY 327
Query: 417 ITLGTDLAQQQGGGNGQQQQAMSFAILRIIRLVRVFRIFKLSRHSKGLQILGHTLRASMR 476
+ +G G + + + F LR++R VR+ RIFKL+RH GL++LGHTLRAS
Sbjct: 328 LEVGLS-----GLSSKAAKDVLGF--LRVVRFVRILRIFKLTRHFVGLRVLGHTLRASTN 380
Query: 477 ELGLLIFFLFIGVILFSSAVYFAEA-----DEPT----THFQSIPDAFWWAVVTMTTVGY 527
E LLI FL +GV++F++ +Y+AE ++P+ T F++IP FWWAVVTMTT+GY
Sbjct: 381 EFLLLIIFLALGVLIFATMIYYAERVGAQPNDPSASEHTQFKNIPIGFWWAVVTMTTLGY 440
Query: 528 GDMKPITVGGKIVGSLCAIAGVLTIALPVPVIVSNFNYFY 567
GDM P T G +VG+LCA+AGVLTIA+PVPVIV+NF +Y
Sbjct: 441 GDMYPQTWSGMLVGALCALAGVLTIAMPVPVIVNNFGMYY 480
>gi|21217563 Shaw-related voltage-gated potassium channel protein 2
isoform KV3.2b [Homo sapiens]
Length = 638
Score = 247 bits (630), Expect = 3e-65
Identities = 159/400 (39%), Positives = 223/400 (55%), Gaps = 70/400 (17%)
Query: 218 EYFFDRNRPSFDAILYYYQSGGRLKRPVNVPFDIFTEEVKFYQL---------------- 261
E+FFDR+ F +L YY++G +L P +V +F EE+ F+ +
Sbjct: 101 EFFFDRHPGVFAYVLNYYRTG-KLHCPADVCGPLFEEELAFWGIDETDVEPCCWMTYRQH 159
Query: 262 --GEEALLKFREDE---GFVREEEDRALPE-------------------NEFKKQIWLLF 297
EEAL F + G ++ED A + ++W LF
Sbjct: 160 RDAEEALDIFETPDLIGGDPGDDEDLAAKRLGIEDAAGLGGPDGKSGRWRRLQPRMWALF 219
Query: 298 EYPESSSPARGIAIVSVLVILISIVIFCLETLPEFRDDRDLVMALSAGGHGGLLNDTSAP 357
E P SS AR IA S+ IL+SI FCLET F ++ + +N TS
Sbjct: 220 EDPYSSRAARFIAFASLFFILVSITTFCLETHEAFNIVKNKTEPV--------INGTSVV 271
Query: 358 HLENSGHTIFNDPFFI-VETVCIVWFSFEFVVRCFACPSQALFFKNIMNIIDIVSILPYF 416
+ I DP VE VC+VWF+FEF+VR P++ F KN++NIID V+ILP++
Sbjct: 272 ----LQYEIETDPALTYVEGVCVVWFTFEFLVRIVFSPNKLEFIKNLLNIIDFVAILPFY 327
Query: 417 ITLGTDLAQQQGGGNGQQQQAMSFAILRIIRLVRVFRIFKLSRHSKGLQILGHTLRASMR 476
+ +G G + + + F LR++R VR+ RIFKL+RH GL++LGHTLRAS
Sbjct: 328 LEVGLS-----GLSSKAAKDVLGF--LRVVRFVRILRIFKLTRHFVGLRVLGHTLRASTN 380
Query: 477 ELGLLIFFLFIGVILFSSAVYFAEA-----DEPT----THFQSIPDAFWWAVVTMTTVGY 527
E LLI FL +GV++F++ +Y+AE ++P+ T F++IP FWWAVVTMTT+GY
Sbjct: 381 EFLLLIIFLALGVLIFATMIYYAERVGAQPNDPSASEHTQFKNIPIGFWWAVVTMTTLGY 440
Query: 528 GDMKPITVGGKIVGSLCAIAGVLTIALPVPVIVSNFNYFY 567
GDM P T G +VG+LCA+AGVLTIA+PVPVIV+NF +Y
Sbjct: 441 GDMYPQTWSGMLVGALCALAGVLTIAMPVPVIVNNFGMYY 480
>gi|24497458 Shaw-related voltage-gated potassium channel protein 2
isoform KV3.2c [Homo sapiens]
Length = 558
Score = 247 bits (630), Expect = 3e-65
Identities = 159/400 (39%), Positives = 223/400 (55%), Gaps = 70/400 (17%)
Query: 218 EYFFDRNRPSFDAILYYYQSGGRLKRPVNVPFDIFTEEVKFYQL---------------- 261
E+FFDR+ F +L YY++G +L P +V +F EE+ F+ +
Sbjct: 101 EFFFDRHPGVFAYVLNYYRTG-KLHCPADVCGPLFEEELAFWGIDETDVEPCCWMTYRQH 159
Query: 262 --GEEALLKFREDE---GFVREEEDRALPE-------------------NEFKKQIWLLF 297
EEAL F + G ++ED A + ++W LF
Sbjct: 160 RDAEEALDIFETPDLIGGDPGDDEDLAAKRLGIEDAAGLGGPDGKSGRWRRLQPRMWALF 219
Query: 298 EYPESSSPARGIAIVSVLVILISIVIFCLETLPEFRDDRDLVMALSAGGHGGLLNDTSAP 357
E P SS AR IA S+ IL+SI FCLET F ++ + +N TS
Sbjct: 220 EDPYSSRAARFIAFASLFFILVSITTFCLETHEAFNIVKNKTEPV--------INGTSVV 271
Query: 358 HLENSGHTIFNDPFFI-VETVCIVWFSFEFVVRCFACPSQALFFKNIMNIIDIVSILPYF 416
+ I DP VE VC+VWF+FEF+VR P++ F KN++NIID V+ILP++
Sbjct: 272 ----LQYEIETDPALTYVEGVCVVWFTFEFLVRIVFSPNKLEFIKNLLNIIDFVAILPFY 327
Query: 417 ITLGTDLAQQQGGGNGQQQQAMSFAILRIIRLVRVFRIFKLSRHSKGLQILGHTLRASMR 476
+ +G G + + + F LR++R VR+ RIFKL+RH GL++LGHTLRAS
Sbjct: 328 LEVGLS-----GLSSKAAKDVLGF--LRVVRFVRILRIFKLTRHFVGLRVLGHTLRASTN 380
Query: 477 ELGLLIFFLFIGVILFSSAVYFAEA-----DEPT----THFQSIPDAFWWAVVTMTTVGY 527
E LLI FL +GV++F++ +Y+AE ++P+ T F++IP FWWAVVTMTT+GY
Sbjct: 381 EFLLLIIFLALGVLIFATMIYYAERVGAQPNDPSASEHTQFKNIPIGFWWAVVTMTTLGY 440
Query: 528 GDMKPITVGGKIVGSLCAIAGVLTIALPVPVIVSNFNYFY 567
GDM P T G +VG+LCA+AGVLTIA+PVPVIV+NF +Y
Sbjct: 441 GDMYPQTWSGMLVGALCALAGVLTIAMPVPVIVNNFGMYY 480
>gi|24497460 Shaw-related voltage-gated potassium channel protein 3
[Homo sapiens]
Length = 757
Score = 235 bits (599), Expect = 1e-61
Identities = 132/289 (45%), Positives = 183/289 (63%), Gaps = 24/289 (8%)
Query: 289 FKKQIWLLFEYPESSSPARGIAIVSVLVILISIVIFCLETLPEFRDDRDLVMALSAGGHG 348
++ ++W LFE P SS AR +A S+ ILISI FCLET F + + ++ G
Sbjct: 272 WQPRVWALFEDPYSSRAARYVAFASLFFILISITTFCLETHEGFIHISNKTVTQASPIPG 331
Query: 349 GLLNDTSAPHLENSGHTIFNDPFFI-VETVCIVWFSFEFVVRCFACPSQALFFKNIMNII 407
AP + + +PF VE VC+VWF+FEF++R CP + F K+ +NII
Sbjct: 332 -------APPENITNVEVETEPFLTYVEGVCVVWFTFEFLMRITFCPDKVEFLKSSLNII 384
Query: 408 DIVSILPYFITLGTDLAQQQGGGNGQQQQAMSFAILRIIRLVRVFRIFKLSRHSKGLQIL 467
D V+ILP+++ +G G + + + F LR++R VR+ RIFKL+RH GL++L
Sbjct: 385 DCVAILPFYLEVGLS-----GLSSKAAKDVLGF--LRVVRFVRILRIFKLTRHFVGLRVL 437
Query: 468 GHTLRASMRELGLLIFFLFIGVILFSSAVYFAE---ADEPT------THFQSIPDAFWWA 518
GHTLRAS E LLI FL +GV++F++ +Y+AE AD T+F++IP FWWA
Sbjct: 438 GHTLRASTNEFLLLIIFLALGVLIFATMIYYAERIGADPDDILGSNHTYFKNIPIGFWWA 497
Query: 519 VVTMTTVGYGDMKPITVGGKIVGSLCAIAGVLTIALPVPVIVSNFNYFY 567
VVTMTT+GYGDM P T G +VG+LCA+AGVLTIA+PVPVIV+NF +Y
Sbjct: 498 VVTMTTLGYGDMYPKTWSGMLVGALCALAGVLTIAMPVPVIVNNFGMYY 546
Score = 61.2 bits (147), Expect = 3e-09
Identities = 40/106 (37%), Positives = 59/106 (55%), Gaps = 13/106 (12%)
Query: 162 GGGGYSSVRYSDCCERVVINVSGLRFETQMKTLAQFPETLLG---DPEKRTQY-FDPLRN 217
GGGG S ++VINV G+R ET TL P T L +PE ++ +DP +
Sbjct: 82 GGGGDSG--------KIVINVGGVRHETYRSTLRTLPGTRLAGLTEPEAAARFDYDPGAD 133
Query: 218 EYFFDRNRPSFDAILYYYQSGGRLKRPVNVPFDIFTEEVKFYQLGE 263
E+FFDR+ F +L YY++ G+L P +V +F EE+ F+ + E
Sbjct: 134 EFFFDRHPGVFAYVLNYYRT-GKLHCPADVCGPLFEEELGFWGIDE 178
>gi|13492973 potassium voltage-gated channel delayed-rectifier
protein S1 [Homo sapiens]
Length = 526
Score = 232 bits (592), Expect = 7e-61
Identities = 147/450 (32%), Positives = 232/450 (51%), Gaps = 63/450 (14%)
Query: 164 GGYSSVRYSDCCERVVINVSGLRFETQMKTLAQFPETLLG---------DPEKRTQYFDP 214
G + +R+ E + +NV G+R + + LA+FP T LG + +D
Sbjct: 38 GPDTGIRWRRSDEALRVNVGGVRRQLSARALARFPGTRLGRLQAAASEEQARRLCDDYDE 97
Query: 215 LRNEYFFDRNRPSFDAILYYYQSGGRLKRPVNVPFDIFTEEVKFYQLGEEALLKFREDEG 274
E++FDR+ F ++L++Y++G L + F +E ++ LGE AL
Sbjct: 98 AAREFYFDRHPGFFLSLLHFYRTG-HLHVLDELCVFAFGQEADYWGLGENALAACCRARY 156
Query: 275 FVRE-------EEDRALPEN------------------------EFKKQIWLLFEYPESS 303
R +ED P + ++++WL E P S
Sbjct: 157 LERRLTQPHAWDEDSDTPSSVDPCPDEISDVQRELARYGAARCGRLRRRLWLTMENPGYS 216
Query: 304 SPARGIAIVSVLVILISIVIFCLETLPEF--RDDRDLVMALSAGGHGGLLNDTSAPHLEN 361
P++ + VS+ V+L SI C+ +LPE+ R+ V A++AG
Sbjct: 217 LPSKLFSCVSISVVLASIAAMCIHSLPEYQAREAAAAVAAVAAG---------------R 261
Query: 362 SGHTIFNDPFFI-VETVCIVWFSFEFVVRCFACPSQALFFKNIMNIIDIVSILPYFITLG 420
S + +DP +E CI WFSFE R PS FF + +N+IDIVS+LP+++TL
Sbjct: 262 SPEGVRDDPVLRRLEYFCIAWFSFEVSSRLLLAPSTRNFFCHPLNLIDIVSVLPFYLTL- 320
Query: 421 TDLAQQQGGGNGQQQQAMSFAILRIIRLVRVFRIFKLSRHSKGLQILGHTLRASMRELGL 480
LA G G ++ ++++ RL+R+FR+ KL+RHS GL+ LG TL+ S RE+G+
Sbjct: 321 --LAGVALGDQGGKEFGHLGKVVQVFRLMRIFRVLKLARHSTGLRSLGATLKHSYREVGI 378
Query: 481 LIFFLFIGVILFSSAVYFAEADEPTTHFQSIPDAFWWAVVTMTTVGYGDMKPITVGGKIV 540
L+ +L +GV +FS Y AE +E F +IP +WW V+MTTVGYGD+ P+TV GK+
Sbjct: 379 LLLYLAVGVSVFSGVAYTAEKEEDVG-FNTIPACWWWGTVSMTTVGYGDVVPVTVAGKLA 437
Query: 541 GSLCAIAGVLTIALPVPVIVSNFNYFYHRE 570
S C + G+L +ALP+ +I + F++FY R+
Sbjct: 438 ASGCILGGILVVALPITIIFNKFSHFYRRQ 467
>gi|25952108 potassium voltage-gated channel delayed-rectifier
protein S3 [Homo sapiens]
Length = 491
Score = 228 bits (582), Expect = 1e-59
Identities = 149/455 (32%), Positives = 228/455 (50%), Gaps = 73/455 (16%)
Query: 176 ERVVINVSGLRFETQMKTLAQFPETLLG------DPEKRTQYFDPLR---NEYFFDRNRP 226
E V +NV G + TL +FP T LG E + D EY+FDRN
Sbjct: 15 ELVNLNVGGFKQSVDQSTLLRFPHTRLGKLLTCHSEEAILELCDDYSVADKEYYFDRNPS 74
Query: 227 SFDAILYYYQSGGRLKRPVNVPFDIFTEEVKFYQLGEEAL-------------------- 266
F +L +Y + G+L + F +E++++ + E +
Sbjct: 75 LFRYVLNFYYT-GKLHVMEELCVFSFCQEIEYWGINELFIDSCCSNRYQERKEENHEKDW 133
Query: 267 ----------LKFREDEGFVRE-EEDRALPENEFKKQIWLLFEYPESSSPARGIAIVSVL 315
F E F +E E+ L + +K+IW+ E P A+ IAI S+
Sbjct: 134 DQKSHDVSTDSSFEESSLFEKELEKFDTLRFGQLRKKIWIRMENPAYCLSAKLIAISSLS 193
Query: 316 VILISIVIFCLETLPEFRDDRDLVMALSAGGHGGLLNDTSAPHLENSGHTIFNDPFFIVE 375
V+L SIV C+ ++ EF+++ G ++D P LE VE
Sbjct: 194 VVLASIVAMCVHSMSEFQNE------------DGEVDD---PVLEG------------VE 226
Query: 376 TVCIVWFSFEFVVRCFACPSQALFFKNIMNIIDIVSILPYFITLGTDLAQQQGGGNGQQQ 435
CI WF+ E VR A P Q F+KN +NIID VSI+P++ TL D +++ +
Sbjct: 227 IACIAWFTGELAVRLAAAPCQKKFWKNPLNIIDFVSIIPFYATLAVDTKEEE----SEDI 282
Query: 436 QAMSFAILRIIRLVRVFRIFKLSRHSKGLQILGHTLRASMRELGLLIFFLFIGVILFSSA 495
+ M +++I+RL+R+FRI KL+RHS GL+ LG TLR S E+GLL+ FL +G+ +FS
Sbjct: 283 ENMG-KVVQILRLMRIFRILKLARHSVGLRSLGATLRHSYHEVGLLLLFLSVGISIFSVL 341
Query: 496 VYFAEADEPTTHFQSIPDAFWWAVVTMTTVGYGDMKPITVGGKIVGSLCAIAGVLTIALP 555
+Y E D+ T+ SIP +WWA ++MTTVGYGD P+T+ GK++ S C I G+L +ALP
Sbjct: 342 IYSVEKDDHTSSLTSIPICWWWATISMTTVGYGDTHPVTLAGKLIASTCIICGILVVALP 401
Query: 556 VPVIVSNFNYFYHRETENEEQTQLTQNAVSCPYLP 590
+ +I + F+ +Y ++ + + C LP
Sbjct: 402 ITIIFNKFSKYYQKQKDIDVDQCSEDAPEKCHELP 436
>gi|20070166 potassium voltage-gated channel, subfamily F, member 1
[Homo sapiens]
Length = 494
Score = 228 bits (580), Expect = 2e-59
Identities = 151/440 (34%), Positives = 233/440 (52%), Gaps = 70/440 (15%)
Query: 165 GYSSVRYSDCCERVVINVSGLRFETQMKTLAQFPETLLGDPEK-----------RTQYFD 213
G S SD E +V+NV G+R L+Q+PET L + +D
Sbjct: 13 GSQSSAASDDIE-IVVNVGGVRQVLYGDLLSQYPETRLAELINCLAGGYDTIFSLCDDYD 71
Query: 214 PLRNEYFFDRNRPSFDAILYYYQSGGRLKRPVNVPFDIFTEEVKFYQLGEEALLKFRED- 272
P + E++FDR+ +F ++ Y G + P F E+ F+++ LKF +D
Sbjct: 72 PGKREFYFDRDPDAFKCVIEVYYFGEVHMKKGICPI-CFKNEMDFWKVD----LKFLDDC 126
Query: 273 ----EGFVREE------------EDRALPENEFK-----KQIWLLFEYPESSSPARGIAI 311
REE +D + E + K +W E PESS PAR +A+
Sbjct: 127 CKSHLSEKREELEEIARRVQLILDDLGVDAAEGRWRRCQKCVWKFLEKPESSCPARVVAV 186
Query: 312 VSVLVILISIVIFCLETLPEFRDDRDLVMALSAGGHGGLLNDTSAPHLENSGHTIFNDPF 371
+S L+IL+S V+ C+ T+PE + L A G N P LEN
Sbjct: 187 LSFLLILVSSVVMCMGTIPELQ-------VLDAEG-----NRVEHPTLEN---------- 224
Query: 372 FIVETVCIVWFSFEFVVRCFACPSQALFFKNIMNIIDIVSILPYFITLG-TDLAQQQGGG 430
VET CI WF+ E+++R F+ P++ F + MNI+D+++ILP++++L T L +
Sbjct: 225 --VETACIGWFTLEYLLRLFSSPNKLHFALSFMNIVDVLAILPFYVSLTLTHLGARMMEL 282
Query: 431 NGQQQQAMSFAILRIIRLVRVFRIFKLSRHSKGLQILGHTLRASMRELGLLIFFLFIGVI 490
QQ + +R++R+ RIFKL+RHS GLQ L + L+ S +ELGLL+ +L +G+
Sbjct: 283 TNVQQAVQA------LRIMRIARIFKLARHSSGLQTLTYALKRSFKELGLLLMYLAVGIF 336
Query: 491 LFSSAVYFAEADEPTTHFQSIPDAFWWAVVTMTTVGYGDMKPITVGGKIVGSLCAIAGVL 550
+FS+ Y E P T F+SIP +FWWA++TMTTVGYGD+ P T GK+ ++ + GV+
Sbjct: 337 VFSALGYTMEQSHPETLFKSIPQSFWWAIITMTTVGYGDIYPKTTLGKLNAAISFLCGVI 396
Query: 551 TIALPVPVIVSNFNYFYHRE 570
IALP+ I++NF +Y+++
Sbjct: 397 AIALPIHPIINNFVRYYNKQ 416
>gi|45383011 potassium voltage-gated channel, delayed-rectifier,
subfamily S, member 2 [Homo sapiens]
Length = 477
Score = 222 bits (565), Expect = 1e-57
Identities = 150/488 (30%), Positives = 244/488 (50%), Gaps = 77/488 (15%)
Query: 180 INVSGLRFETQMKTLAQFPETLLG------DPEKRTQY---FDPLRNEYFFDRNRPSFDA 230
INV G + + TL +FPET LG E + +D ++ E++FDRN F
Sbjct: 21 INVGGFKRRLRSHTLLRFPETRLGRLLLCHSREAILELCDDYDDVQREFYFDRNPELFPY 80
Query: 231 ILYYYQSGGRLKRPVNVPFDIFTEEVKFYQLGE---EALLKFREDEGFVREEEDR----- 282
+L++Y +G +L + F++E++++ + E ++ + V E+++
Sbjct: 81 VLHFYHTG-KLHVMAELCVFSFSQEIEYWGINEFFIDSCCSYSYHGRKVEPEQEKWDEQS 139
Query: 283 -----------------------ALPENEFKKQIWLLFEYPESSSPARGIAIVSVLVILI 319
P F++Q+WL + P S +R +I+S+LV++
Sbjct: 140 DQESTTSSFDEILAFYNDASKFDGQPLGNFRRQLWLALDNPGYSVLSRVFSILSILVVMG 199
Query: 320 SIVIFCLETLPEFRDDRDLVMALSAGGHGGLLNDTSAPHLENSGHTIFNDPFF-IVETVC 378
SI+ CL +LP+F+ + S G G DP F IVE
Sbjct: 200 SIITMCLNSLPDFQ------IPDSQGNPG-------------------EDPRFEIVEHFG 234
Query: 379 IVWFSFEFVVRCFACPSQALFFKNIMNIIDIVSILPYFITLGTDLAQQQGGGNGQQQQAM 438
I WF+FE V R P FFKN +N+ID++SI+P++ITL +L + A
Sbjct: 235 IAWFTFELVARFAVAPDFLKFFKNALNLIDLMSIVPFYITLVVNLVVES-----TPTLAN 289
Query: 439 SFAILRIIRLVRVFRIFKLSRHSKGLQILGHTLRASMRELGLLIFFLFIGVILFSSAVYF 498
+ +++RL+R+FRI KL+RHS GL+ LG TL+ S +E+GLL+ +L +G+ +FS Y
Sbjct: 290 LGRVAQVLRLMRIFRILKLARHSTGLRSLGATLKYSYKEVGLLLLYLSVGISIFSVVAYT 349
Query: 499 AEADEPTTHFQSIPDAFWWAVVTMTTVGYGDMKPITVGGKIVGSLCAIAGVLTIALPVPV 558
E +E +IP +WWA V+MTTVGYGD+ P T GK+ S C +AG+L + LP+ +
Sbjct: 350 IEKEE-NEGLATIPACWWWATVSMTTVGYGDVVPGTTAGKLTASACILAGILVVVLPITL 408
Query: 559 IVSNFNYFYHRETENEEQTQLTQNAVSCPYLPSNLLKKFRS----STSSSLGDKSEYLEM 614
I + F++FY R+ + E + +PS L+ + + S +SL + S
Sbjct: 409 IFNKFSHFYRRQKQLESAMRSCDFGDGMKEVPSVNLRDYYAHKVKSLMASLTNMSRSSPS 468
Query: 615 EEGVKESL 622
E + +SL
Sbjct: 469 ELSLNDSL 476
>gi|7657289 potassium channel, subfamily V, member 1 [Homo sapiens]
Length = 500
Score = 219 bits (557), Expect = 8e-57
Identities = 157/524 (29%), Positives = 245/524 (46%), Gaps = 103/524 (19%)
Query: 146 DHGDECSYTDLLPQDEGGGGYSSVRYSDCCERVVINVSGLRFETQMKTLAQFPETLLG-- 203
D G S + EG G + DC +NV G RF + L+ FP T LG
Sbjct: 14 DSGSLTSLDSSVFCSEGEG--EPLALGDC---FTVNVGGSRFVLSQQALSCFPHTRLGKL 68
Query: 204 -----------------DPEKRTQYFDPLRNEYFFDRNRPSFDAILYYYQSGGRLKRPVN 246
P + +P+ NEYFFDR+ +F +L+YY++G RL
Sbjct: 69 AVVVASYRRPGALAAVPSPLELCDDANPVDNEYFFDRSSQAFRYVLHYYRTG-RLHVMEQ 127
Query: 247 VPFDIFTEEVKFYQLGEEALLKFREDEGFVREEEDRALP--------------ENEF--- 289
+ F +E++++ + E ++ D F R+E L E +F
Sbjct: 128 LCALSFLQEIQYWGIDELSIDSCCRDRYFRRKELSETLDFKKDTEDQESQHESEQDFSQG 187
Query: 290 -----KKQIWLLFEYPESSSPARGIAIVSVLVILISIVIFCLETLPEFRDDRDLVMALSA 344
++++W + E P SS+ AR ++S++ +++SI+ L + D L+
Sbjct: 188 PCPTVRQKLWNILEKPGSSTAARIFGVISIIFVVVSIINMALMSAELSWLDLQLLE---- 243
Query: 345 GGHGGLLNDTSAPHLENSGHTIFNDPFFIVETVCIVWFSFEFVVRCFACPSQALFFKNIM 404
I+E VCI WF+ EFV+R + F + +
Sbjct: 244 ----------------------------ILEYVCISWFTGEFVLRFLCVRDRCRFLRKVP 275
Query: 405 NIIDIVSILPYFITLGTDLAQQQGGGNGQQQQAMSFAILRIIRLVRVFRIFKLSRHSKGL 464
NIID+++ILP++ITL L + G Q+ I++++RL+R R+ KL RHS GL
Sbjct: 276 NIIDLLAILPFYITL---LVESLSGSQTTQELENVGRIVQVLRLLRALRMLKLGRHSTGL 332
Query: 465 QILGHTLRASMRELGLLIFFLFIGVILFSSAVYFAEADEPTTHFQSIPDAFWWAVVTMTT 524
+ LG T+ E+GLL+ FL +G+ +FS+ YFAE P T F S+P A+WWA +MTT
Sbjct: 333 RSLGMTITQCYEEVGLLLLFLSVGISIFSTVEYFAEQSIPDTTFTSVPCAWWWATTSMTT 392
Query: 525 VGYGDMKPITVGGKIVGSLCAIAGVLTIALPVPVIVSNFNYFYH-------RETENEEQT 577
VGYGD++P T GKIV +C ++G+L +ALP+ +I F+ Y + E
Sbjct: 393 VGYGDIRPDTTTGKIVAFMCILSGILVLALPIAIINDRFSACYFTLKLKEAAVRQREALK 452
Query: 578 QLTQNAVSCPYLPSNLLKKF--------------RSSTSSSLGD 607
+LT+N + Y+ NL + R+ST SS GD
Sbjct: 453 KLTKNIATDSYISVNLRDVYARSIMEMLRLKGRERASTRSSGGD 496
>gi|27436988 potassium voltage-gated channel, subfamily G, member 1
[Homo sapiens]
Length = 513
Score = 218 bits (555), Expect = 1e-56
Identities = 155/462 (33%), Positives = 232/462 (50%), Gaps = 72/462 (15%)
Query: 156 LLPQDEGGGGYSSVRYSDCCERVVINVSGLRFETQMKTLAQFPETLLGDPEKRTQYFDPL 215
L PQDE G D R++INV G+++ TL +FP T LG + T + D L
Sbjct: 46 LRPQDEPRQGCQP---EDRRRRIIINVGGIKYSLPWTTLDEFPLTRLGQLKACTNFDDIL 102
Query: 216 R---------NEYFFDRNRPSFDAILYYYQSGGRLKRPVNVPFDIFTEEVKFYQLGEEAL 266
NE+FFDRN +F IL + ++G +L+ + F EE+ ++ + E+ L
Sbjct: 103 NVCDDYDVTCNEFFFDRNPGAFGTILTFLRAG-KLRLLREMCALSFQEELLYWGIAEDHL 161
Query: 267 ---------LKFREDEGFV-REEEDRALP----------ENEFK-----KQIWLLFEYPE 301
K E V REEED AL E E + +++ + E P
Sbjct: 162 DGCCKRRYLQKIEEFAEMVEREEEDDALDSEGRDSEGPAEGEGRLGRCMRRLRDMVERPH 221
Query: 302 SSSPARGIAIVSVLVILISIVIFCLETLPEFRDDRDLVMALSAGGHGGLLNDTSAPHLEN 361
S P + A +SVL + ++ V + TLP R++ + H
Sbjct: 222 SGLPGKVFACLSVLFVTVTAVNLSVSTLPSLREEEE------------------QGHCSQ 263
Query: 362 SGHTIFNDPFFIVETVCIVWFSFEFVVRCFACPSQALFFKNIMNIIDIVSILPYFITLGT 421
H +F IVE+VC+ WFS EF++R PS+ F ++ + +ID+V+ILPY+ITL
Sbjct: 264 MCHNVF-----IVESVCVGWFSLEFLLRLIQAPSKFAFLRSPLTLIDLVAILPYYITLLV 318
Query: 422 DLA----QQQGGGNGQQQQAMSFAILRIIRLVRVFRIFKLSRHSKGLQILGHTLRASMRE 477
D A ++ G GN + +LR++R +R+ + +L+RHS GLQ LG T R RE
Sbjct: 319 DGAAAGRRKPGAGNSYLDKVG--LVLRVLRALRILYVMRLARHSLGLQTLGLTARRCTRE 376
Query: 478 LGLLIFFLFIGVILFSSAVYFAE---ADEPTTHFQSIPDAFWWAVVTMTTVGYGDMKPIT 534
GLL+ FL + + LF+ +Y E AD P F SIP +WWAV+TMTTVGYGDM P +
Sbjct: 377 FGLLLLFLCVAIALFAPLLYVIENEMADSP--EFTSIPACYWWAVITMTTVGYGDMVPRS 434
Query: 535 VGGKIVGSLCAIAGVLTIALPVPVIVSNFNYFYHRETENEEQ 576
G++V ++G+L +A PV I F+ Y + +E+
Sbjct: 435 TPGQVVALSSILSGILLMAFPVTSIFHTFSRSYLELKQEQER 476
>gi|19071574 potassium voltage-gated channel, subfamily G, member 3
isoform 1 [Homo sapiens]
Length = 436
Score = 207 bits (528), Expect = 2e-53
Identities = 143/431 (33%), Positives = 223/431 (51%), Gaps = 64/431 (14%)
Query: 178 VVINVSGLRFETQMKTLAQFP----ETLLGDPEKRTQY-----FDPLRNEYFFDRNRPSF 228
VV+NV G R+ + L FP L G +R +D RNEYFFDR+ +F
Sbjct: 11 VVLNVGGARYSLSRELLKDFPLRRVSRLHGCRSERDVLEVCDDYDRERNEYFFDRHSEAF 70
Query: 229 DAILYYYQSGGRLKRPVNVPFDIFTEEVKFYQLGEEALLKF------------------R 270
IL Y + G+L+ + F E+ ++ L E A L++
Sbjct: 71 GFILLYVRGHGKLRFAPRMCELSFYNEMIYWGL-EGAHLEYCCQRRLDDRMSDTYTFYSA 129
Query: 271 EDEGFVREEEDR-----ALPENEFKKQIWLLFEYPESSSPARGIAIVSVLVILISIVIFC 325
++ G + +E R A P + +++ FE P SS A+ +A VSV+ +++S+V+ C
Sbjct: 130 DEPGVLGRDEARPGGAEAAPSRRWLERMRRTFEEPTSSLAAQILASVSVVFVIVSMVVLC 189
Query: 326 LETLPEFRDDRDLVMALSAGGHGGLLNDTS----APHLENSGHTIFNDPFFIVETVCIVW 381
TLP++R+ A L+D S P E SG I+E +CI W
Sbjct: 190 ASTLPDWRN---------AAADNRSLDDRSRYSAGPGREPSG---------IIEAICIGW 231
Query: 382 FSFEFVVRCFACPSQALFFKNIMNIIDIVSILPYFITLGTDLAQQQGGGNGQQQQAMSFA 441
F+ E +VR ++ F K +NIID+++I PY+I++ L G N Q Q+A
Sbjct: 232 FTAECIVRFIVSKNKCEFVKRPLNIIDLLAITPYYISV---LMTVFTGENSQLQRAG--V 286
Query: 442 ILRIIRLVRVFRIFKLSRHSKGLQILGHTLRASMRELGLLIFFLFIGVILFSSAVYFAE- 500
LR++R++R+F + KL+RH GLQ LG TL+ RE+ +L+ F+ + + +FS+ E
Sbjct: 287 TLRVLRMMRIFWVIKLARHFIGLQTLGLTLKRCYREMVMLLVFICVAMAIFSALSQLLEH 346
Query: 501 ---ADEPTTHFQSIPDAFWWAVVTMTTVGYGDMKPITVGGKIVGSLCAIAGVLTIALPVP 557
+ F SIP A WW +++MTTVGYGDM PITV G+I+G +C ++G++ +ALP+
Sbjct: 347 GLDLETSNKDFTSIPAACWWVIISMTTVGYGDMYPITVPGRILGGVCVVSGIVLLALPIT 406
Query: 558 VIVSNFNYFYH 568
I +F YH
Sbjct: 407 FIYHSFVQCYH 417
Database: hs.faa
Posted date: Aug 4, 2009 4:42 PM
Number of letters in database: 18,247,518
Number of sequences in database: 37,866
Lambda K H
0.319 0.135 0.397
Gapped
Lambda K H
0.267 0.0410 0.140
Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Hits to DB: 25,753,589
Number of Sequences: 37866
Number of extensions: 1288206
Number of successful extensions: 27118
Number of sequences better than 10.0: 30
Number of HSP's better than 10.0 without gapping: 535
Number of HSP's successfully gapped in prelim test: 279
Number of HSP's that attempted gapping in prelim test: 15266
Number of HSP's gapped (non-prelim): 6135
length of query: 653
length of database: 18,247,518
effective HSP length: 109
effective length of query: 544
effective length of database: 14,120,124
effective search space: 7681347456
effective search space used: 7681347456
T: 11
A: 40
X1: 16 ( 7.4 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 41 (21.7 bits)
S2: 65 (29.6 bits)
Search results were obtained with NCBI BLAST and RefSeq entries.
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Guide to the Human Genome
Copyright © 2010 by Stewart Scherer. All rights reserved.