Guide to the Human Genome
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Search of human proteins with 4504567

BLASTP 2.2.11 [Jun-05-2005]


Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer, 
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), 
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs",  Nucleic Acids Res. 25:3389-3402.

Query= gi|4504567 interferon regulatory factor 8 [Homo sapiens]
         (426 letters)

Database: hs.faa 
           37,866 sequences; 18,247,518 total letters

Searching..................................................done

                                                                 Score    E
Sequences producing significant alignments:                      (bits) Value

gi|4504567 interferon regulatory factor 8 [Homo sapiens]              882   0.0  
gi|167555104 interferon regulatory factor 4 [Homo sapiens]            302   3e-82
gi|25282407 interferon-stimulated transcription factor 3, gamma ...   216   3e-56
gi|5453700 interferon regulatory factor 6 [Homo sapiens]              206   3e-53
gi|148833515 interferon regulatory factor 5 isoform c [Homo sapi...   200   2e-51
gi|148833492 interferon regulatory factor 5 isoform c [Homo sapi...   200   2e-51
gi|148833488 interferon regulatory factor 5 isoform c [Homo sapi...   200   2e-51
gi|148833494 interferon regulatory factor 5 isoform d [Homo sapi...   197   2e-50
gi|4504727 interferon regulatory factor 5 isoform a [Homo sapiens]    196   3e-50
gi|148833496 interferon regulatory factor 5 isoform b [Homo sapi...   196   3e-50
gi|14249182 interferon regulatory factor 5 isoform b [Homo sapiens]   196   3e-50
gi|4504725 interferon regulatory factor 3 [Homo sapiens]              129   7e-30
gi|4504721 interferon regulatory factor 1 [Homo sapiens]              118   1e-26
gi|153082752 interferon regulatory factor 2 [Homo sapiens]            117   2e-26
gi|98985819 interferon regulatory factor 7 isoform d [Homo sapiens]    89   8e-18
gi|4758610 interferon regulatory factor 7 isoform a [Homo sapiens]     89   8e-18
gi|4809284 interferon regulatory factor 7 isoform b [Homo sapiens]     89   8e-18
gi|239757474 PREDICTED: similar to hCG1785205 [Homo sapiens]           57   2e-08
gi|239751984 PREDICTED: similar to hCG1785205 [Homo sapiens]           57   2e-08
gi|239746471 PREDICTED: hypothetical protein XP_002343764 [Homo ...    57   2e-08
gi|32967601 ankyrin 3 isoform 1 [Homo sapiens]                         32   1.4  
gi|14149680 extended synaptotagmin-like protein 1 [Homo sapiens]       31   1.9  
gi|9256590 protocadherin alpha 5 isoform 1 precursor [Homo sapiens]    31   2.4  
gi|14165416 protocadherin alpha 5 isoform 2 precursor [Homo sapi...    31   2.4  
gi|25777608 NLR family member X1 isoform 1 [Homo sapiens]              30   4.2  
gi|25777610 NLR family member X1 isoform 2 [Homo sapiens]              30   4.2  
gi|157364934 fibrosin [Homo sapiens]                                   30   4.2  
gi|49355778 inter-alpha trypsin inhibitor heavy chain precursor ...    30   5.5  
gi|153945780 inter-alpha trypsin inhibitor heavy chain precursor...    30   5.5  
gi|166235140 seizure related 6 homolog (mouse)-like 2 isoform 4 ...    29   7.1  

>gi|4504567 interferon regulatory factor 8 [Homo sapiens]
          Length = 426

 Score =  882 bits (2279), Expect = 0.0
 Identities = 426/426 (100%), Positives = 426/426 (100%)

Query: 1   MCDRNGGRRLRQWLIEQIDSSMYPGLIWENEEKSMFRIPWKHAGKQDYNQEVDASIFKAW 60
           MCDRNGGRRLRQWLIEQIDSSMYPGLIWENEEKSMFRIPWKHAGKQDYNQEVDASIFKAW
Sbjct: 1   MCDRNGGRRLRQWLIEQIDSSMYPGLIWENEEKSMFRIPWKHAGKQDYNQEVDASIFKAW 60

Query: 61  AVFKGKFKEGDKAEPATWKTRLRCALNKSPDFEEVTDRSQLDISEPYKVYRIVPEEEQKC 120
           AVFKGKFKEGDKAEPATWKTRLRCALNKSPDFEEVTDRSQLDISEPYKVYRIVPEEEQKC
Sbjct: 61  AVFKGKFKEGDKAEPATWKTRLRCALNKSPDFEEVTDRSQLDISEPYKVYRIVPEEEQKC 120

Query: 121 KLGVATAGCVNEVTEMECGRSEIDELIKEPSVDDYMGMIKRSPSPPEACRSQLLPDWWAQ 180
           KLGVATAGCVNEVTEMECGRSEIDELIKEPSVDDYMGMIKRSPSPPEACRSQLLPDWWAQ
Sbjct: 121 KLGVATAGCVNEVTEMECGRSEIDELIKEPSVDDYMGMIKRSPSPPEACRSQLLPDWWAQ 180

Query: 181 QPSTGVPLVTGYTTYDAHHSAFSQMVISFYYGGKLVGQATTTCPEGCRLSLSQPGLPGTK 240
           QPSTGVPLVTGYTTYDAHHSAFSQMVISFYYGGKLVGQATTTCPEGCRLSLSQPGLPGTK
Sbjct: 181 QPSTGVPLVTGYTTYDAHHSAFSQMVISFYYGGKLVGQATTTCPEGCRLSLSQPGLPGTK 240

Query: 241 LYGPEGLELVRFPPADAIPSERQRQVTRKLFGHLERGVLLHSSRQGVFVKRLCQGRVFCS 300
           LYGPEGLELVRFPPADAIPSERQRQVTRKLFGHLERGVLLHSSRQGVFVKRLCQGRVFCS
Sbjct: 241 LYGPEGLELVRFPPADAIPSERQRQVTRKLFGHLERGVLLHSSRQGVFVKRLCQGRVFCS 300

Query: 301 GNAVVCKGRPNKLERDEVVQVFDTSQFFRELQQFYNSQGRLPDGRVVLCFGEEFPDMAPL 360
           GNAVVCKGRPNKLERDEVVQVFDTSQFFRELQQFYNSQGRLPDGRVVLCFGEEFPDMAPL
Sbjct: 301 GNAVVCKGRPNKLERDEVVQVFDTSQFFRELQQFYNSQGRLPDGRVVLCFGEEFPDMAPL 360

Query: 361 RSKLILVQIEQLYVRQLAEEAGKSCGAGSVMQAPEEPPPDQVFRMFPDICASHQRSFFRE 420
           RSKLILVQIEQLYVRQLAEEAGKSCGAGSVMQAPEEPPPDQVFRMFPDICASHQRSFFRE
Sbjct: 361 RSKLILVQIEQLYVRQLAEEAGKSCGAGSVMQAPEEPPPDQVFRMFPDICASHQRSFFRE 420

Query: 421 NQQITV 426
           NQQITV
Sbjct: 421 NQQITV 426


>gi|167555104 interferon regulatory factor 4 [Homo sapiens]
          Length = 451

 Score =  302 bits (774), Expect = 3e-82
 Identities = 181/415 (43%), Positives = 233/415 (56%), Gaps = 46/415 (11%)

Query: 6   GGRRLRQWLIEQIDSSMYPGLIWENEEKSMFRIPWKHAGKQDYNQEVDASIFKAWAVFKG 65
           G  +LRQWLI+QIDS  YPGL+WENEEKS+FRIPWKHAGKQDYN+E DA++FKAWA+FKG
Sbjct: 20  GNGKLRQWLIDQIDSGKYPGLVWENEEKSIFRIPWKHAGKQDYNREEDAALFKAWALFKG 79

Query: 66  KFKEG-DKAEPATWKTRLRCALNKSPDFEEVTDRSQLDISEPYKVYRIVPEEEQKCKLGV 124
           KF+EG DK +P TWKTRLRCALNKS DFEE+ +RSQLDIS+PYKVYRIVPE  +K    +
Sbjct: 80  KFREGIDKPDPPTWKTRLRCALNKSNDFEELVERSQLDISDPYKVYRIVPEGAKKGAKQL 139

Query: 125 ATAGCVNEVTE--------MECGRSEIDELIKEPSVDDYMGMIKRSPSPP---------- 166
                   ++               ++   +  P    +   +   P P           
Sbjct: 140 TLEDPQMSMSHPYTMTTPYPSLPAQQVHNYMMPPLDRSWRDYVPDQPHPEIPYQCPMTFG 199

Query: 167 --------EACRS--QLLPDWWAQQP----STGVPLVTGYTTYDAHHSAFSQMVISFYYG 212
                    AC +  Q+   ++A  P    + GVP      + +A   +  ++ I  YY 
Sbjct: 200 PRGHHWQGPACENGCQVTGTFYACAPPESQAPGVPTEPSIRSAEALAFSDCRLHICLYYR 259

Query: 213 GKLVGQATTTCPEGCRLSLSQPGLPGTKLYGPEGLELVRFP-PADAIPSERQRQVTRKLF 271
             LV + TT+ PEGCR+S           Y    L+ V FP P D      QR+   KL 
Sbjct: 260 EILVKELTTSSPEGCRISHGH-------TYDASNLDQVLFPYPED----NGQRKNIEKLL 308

Query: 272 GHLERGVLLHSSRQGVFVKRLCQGRVFCSGNAVVCKGRPNKLERDEVVQVFDTSQFFREL 331
            HLERGV+L  +  G++ KRLCQ R++  G   +C  RPNKLERD+  ++FDT QF  EL
Sbjct: 309 SHLERGVVLWMAPDGLYAKRLCQSRIYWDGPLALCNDRPNKLERDQTCKLFDTQQFLSEL 368

Query: 332 QQFYNSQGRLPDGRVVLCFGEEFPDMAPLRSKLILVQIEQLYVRQLAEEAGKSCG 386
           Q F +    LP  +V LCFGEEFPD    R KLI   +E L  RQL   A ++ G
Sbjct: 369 QAFAHHGRSLPRFQVTLCFGEEFPDPQRQR-KLITAHVEPLLARQLYYFAQQNSG 422


>gi|25282407 interferon-stimulated transcription factor 3, gamma
           48kDa [Homo sapiens]
          Length = 393

 Score =  216 bits (550), Expect = 3e-56
 Identities = 127/386 (32%), Positives = 203/386 (52%), Gaps = 27/386 (6%)

Query: 8   RRLRQWLIEQIDSSMYPGLIWENEEKSMFRIPWKHAGKQDYNQEVDASIFKAWAVFKGKF 67
           R+LR W++EQ++S  +PG+ W++  K+MFRIPWKHAGKQD+ ++ DA+ FKAWA+FKGK+
Sbjct: 10  RKLRNWVVEQVESGQFPGVCWDDTAKTMFRIPWKHAGKQDFREDQDAAFFKAWAIFKGKY 69

Query: 68  KEGDKAEPATWKTRLRCALNKSPDFEEVTDRSQLDISEPYKVYRIVPEEEQKCKLGVATA 127
           KEGD   PA WKTRLRCALNKS +F+EV +R ++D++EPYKVY+++P      + G    
Sbjct: 70  KEGDTGGPAVWKTRLRCALNKSSEFKEVPERGRMDVAEPYKVYQLLPPGIVSGQPGTQKV 129

Query: 128 GCVNEVTEMECGRSEIDELIK----EPSVDDYMGMIKRSPSPPEACRSQLLPDWWAQQPS 183
               + + +   R E ++ ++     PSV       +   +   A  S +     +  P 
Sbjct: 130 PSKRQHSSVSSERKEEEDAMQNCTLSPSVLQDSLNNEEEGASGGAVHSDIGSSSSSSSPE 189

Query: 184 TGVPLVTGYTTYDAHHSAFS---------QMVISFYYGGKLVGQATTTCPEGCRLSLSQP 234
                 T    +     +            ++++F Y G++VG+A     + CRL     
Sbjct: 190 PQEVTDTTEAPFQGDQRSLEFLLPPEPDYSLLLTFIYNGRVVGEAQVQSLD-CRLVAEPS 248

Query: 235 GLPGTKLYGPEGLELVRFPPADAIPSERQRQVTRKLFGHLERGVLLHSSRQGVFVKRLCQ 294
           G           +E V FP    +      + T++L   LERG+L+ S+ +G+FV+RLC 
Sbjct: 249 G-------SESSMEQVLFPKPGPL------EPTQRLLSQLERGILVASNPRGLFVQRLCP 295

Query: 295 GRVFCSGNAVVCKGRPNKLERDEVVQVFDTSQFFRELQQFYNSQGRLPDGRVVLCFGEEF 354
             +  +         P+ L  +E V++F T+ F R+L +++   G  P  +V L F EE 
Sbjct: 296 IPISWNAPQAPPGPGPHLLPSNECVELFRTAYFCRDLVRYFQGLGPPPKFQVTLNFWEES 355

Query: 355 PDMAPLRSKLILVQIEQLYVRQLAEE 380
              +     LI V++EQ + R L E+
Sbjct: 356 HGSSHTPQNLITVKMEQAFARYLLEQ 381


>gi|5453700 interferon regulatory factor 6 [Homo sapiens]
          Length = 467

 Score =  206 bits (524), Expect = 3e-53
 Identities = 141/415 (33%), Positives = 212/415 (51%), Gaps = 37/415 (8%)

Query: 9   RLRQWLIEQIDSSMYPGLIWENEEKSMFRIPWKHAGKQDYNQEVDASIFKAWAVFKGKFK 68
           RL+ WL+ Q+DS +YPGLIW + +   F+IPWKHA +    QE + +IFKAWAV  GK++
Sbjct: 9   RLKPWLVAQVDSGLYPGLIWLHRDSKRFQIPWKHATRHSPQQEEENTIFKAWAVETGKYQ 68

Query: 69  EG-DKAEPATWKTRLRCALNKSPDFEEVTDRSQLDISEPYKVYRIVP-EEEQKCKLGVAT 126
           EG D  +PA WK +LRCALNKS +F  + D ++     P K+Y++    + Q   +   +
Sbjct: 69  EGVDDPDPAKWKAQLRCALNKSREFNLMYDGTKEVPMNPVKIYQVCDIPQPQGSIINPGS 128

Query: 127 AGCV------NEVTEMECGRSEIDELIKEPSVDDYMGMIKRSPSP--------------- 165
            G        N+V E E    E+D+      + D    +  + SP               
Sbjct: 129 TGSAPWDEKDNDVDE-EDEEDELDQSQHHVPIQDTFPFLNINGSPMAPASVGNCSVGNCS 187

Query: 166 PEACRSQLLPDWWAQQPSTGVPLVTGYTTYDAHHSA--FSQMVISFYYGGKLVGQA-TTT 222
           PEA   +  P    +      P+   Y++ +   S+   + + I F Y GK  GQ  T +
Sbjct: 188 PEAVWPKTEP---LEMEVPQAPIQPFYSSPELWISSLPMTDLDIKFQYRGKEYGQTMTVS 244

Query: 223 CPEGCRLSLSQPG-LPG-TKLYGPEGLELVRFPPADAIPSERQRQVTRKLFGHLERGVLL 280
            P+GCRL     G +P   +L+GP  LE V+FP  + I +E+Q+  T KL   ++RG++L
Sbjct: 245 NPQGCRLFYGDLGPMPDQEELFGPVSLEQVKFPGPEHITNEKQKLFTSKLLDVMDRGLIL 304

Query: 281 HSSRQGVFVKRLCQGRVFCSGNAVVCKGRPNKLERDEVVQVFDTSQFFRELQQFYNSQ-G 339
             S   ++  RLCQ +V+ SG        PN +ER + V++F    F  +L      Q  
Sbjct: 305 EVSGHAIYAIRLCQCKVYWSGPCAPSLVAPNLIERQKKVKLFCLETFLSDLIAHQKGQIE 364

Query: 340 RLPDGRVVLCFGEEFPDMAPLRSKLILVQIEQLYVRQLAE----EAGKSCGAGSV 390
           + P   + LCFGEE+PD  PL  KLILVQ+  +  R + E    +  +S  +GSV
Sbjct: 365 KQPPFEIYLCFGEEWPDGKPLERKLILVQVIPVVARMIYEMFSGDFTRSFDSGSV 419


>gi|148833515 interferon regulatory factor 5 isoform c [Homo
           sapiens]
          Length = 488

 Score =  200 bits (508), Expect = 2e-51
 Identities = 148/410 (36%), Positives = 197/410 (48%), Gaps = 46/410 (11%)

Query: 9   RLRQWLIEQIDSSMYPGLIWENEEKSMFRIPWKHAGKQDYNQEVDASIFKAWAVFKGKFK 68
           RL+ WL+ Q++S  YPGL W N EK +F IPW+HA +   +Q+ D +IFKAWA   GK+ 
Sbjct: 16  RLKPWLVAQVNSCQYPGLQWVNGEKKLFCIPWRHATRHGPSQDGDNTIFKAWAKETGKYT 75

Query: 69  EG-DKAEPATWKTRLRCALNKSPDFEEVTDRSQLDISEPYKVYRI-----VPEEEQKCKL 122
           EG D+A+PA WK  LRCALNKS DF  + D  +    +PYK+Y +      P + Q  + 
Sbjct: 76  EGVDEADPAKWKANLRCALNKSRDFRLIYDGPRDMPPQPYKIYEVCSNGPAPTDSQPPED 135

Query: 123 GVATAGCVNEVTEMECGRS----EIDELIKEPSV--------DDYMGMIKRSPSP----- 165
               AG   E  E E  R      + E +K P             +G     PSP     
Sbjct: 136 YSFGAG-EEEEEEEELQRMLPSLSLTEDVKWPPTLQPPTLQPPVVLGPPAPDPSPLAPPP 194

Query: 166 --PEACRSQL--------LPDWWAQQPSTGVPLVTGYTTYDAHHSAFSQMVISFYYGGKL 215
             P   R  L        LP   A  P  G  L+        H    + + I F Y G+ 
Sbjct: 195 GNPAGFRELLSEVLEPGPLP---ASLPPAGEQLLPD-LLISPHMLPLTDLEIKFQYRGRP 250

Query: 216 VGQATTTCPEGCRLSLSQPGLPGT----KLYGPEGLELVRFPPADAIPSERQRQVTRKLF 271
               T + P GCRL  SQ  L  T    +L+GP  LE VRFP  + IPS++QR  T +L 
Sbjct: 251 PRALTISNPHGCRLFYSQ--LEATQEQVELFGPISLEQVRFPSPEDIPSDKQRFYTNQLL 308

Query: 272 GHLERGVLLHSSRQGVFVKRLCQGRVFCSGN-AVVCKGRPNKLERDEVVQVFDTSQFFRE 330
             L+RG++L    Q ++  RLCQ +VF SG  A      PN ++R+   ++F    F  E
Sbjct: 309 DVLDRGLILQLQGQDLYAIRLCQCKVFWSGPCASAHDSCPNPIQREVKTKLFSLEHFLNE 368

Query: 331 LQQFYNSQGRLPDG-RVVLCFGEEFPDMAPLRSKLILVQIEQLYVRQLAE 379
           L  F   Q   P    +  CFGEE+PD  P   KLI VQ+  +  R L E
Sbjct: 369 LILFQKGQTNTPPPFEIFFCFGEEWPDRKPREKKLITVQVVPVAARLLLE 418


>gi|148833492 interferon regulatory factor 5 isoform c [Homo
           sapiens]
          Length = 488

 Score =  200 bits (508), Expect = 2e-51
 Identities = 148/410 (36%), Positives = 197/410 (48%), Gaps = 46/410 (11%)

Query: 9   RLRQWLIEQIDSSMYPGLIWENEEKSMFRIPWKHAGKQDYNQEVDASIFKAWAVFKGKFK 68
           RL+ WL+ Q++S  YPGL W N EK +F IPW+HA +   +Q+ D +IFKAWA   GK+ 
Sbjct: 16  RLKPWLVAQVNSCQYPGLQWVNGEKKLFCIPWRHATRHGPSQDGDNTIFKAWAKETGKYT 75

Query: 69  EG-DKAEPATWKTRLRCALNKSPDFEEVTDRSQLDISEPYKVYRI-----VPEEEQKCKL 122
           EG D+A+PA WK  LRCALNKS DF  + D  +    +PYK+Y +      P + Q  + 
Sbjct: 76  EGVDEADPAKWKANLRCALNKSRDFRLIYDGPRDMPPQPYKIYEVCSNGPAPTDSQPPED 135

Query: 123 GVATAGCVNEVTEMECGRS----EIDELIKEPSV--------DDYMGMIKRSPSP----- 165
               AG   E  E E  R      + E +K P             +G     PSP     
Sbjct: 136 YSFGAG-EEEEEEEELQRMLPSLSLTEDVKWPPTLQPPTLQPPVVLGPPAPDPSPLAPPP 194

Query: 166 --PEACRSQL--------LPDWWAQQPSTGVPLVTGYTTYDAHHSAFSQMVISFYYGGKL 215
             P   R  L        LP   A  P  G  L+        H    + + I F Y G+ 
Sbjct: 195 GNPAGFRELLSEVLEPGPLP---ASLPPAGEQLLPD-LLISPHMLPLTDLEIKFQYRGRP 250

Query: 216 VGQATTTCPEGCRLSLSQPGLPGT----KLYGPEGLELVRFPPADAIPSERQRQVTRKLF 271
               T + P GCRL  SQ  L  T    +L+GP  LE VRFP  + IPS++QR  T +L 
Sbjct: 251 PRALTISNPHGCRLFYSQ--LEATQEQVELFGPISLEQVRFPSPEDIPSDKQRFYTNQLL 308

Query: 272 GHLERGVLLHSSRQGVFVKRLCQGRVFCSGN-AVVCKGRPNKLERDEVVQVFDTSQFFRE 330
             L+RG++L    Q ++  RLCQ +VF SG  A      PN ++R+   ++F    F  E
Sbjct: 309 DVLDRGLILQLQGQDLYAIRLCQCKVFWSGPCASAHDSCPNPIQREVKTKLFSLEHFLNE 368

Query: 331 LQQFYNSQGRLPDG-RVVLCFGEEFPDMAPLRSKLILVQIEQLYVRQLAE 379
           L  F   Q   P    +  CFGEE+PD  P   KLI VQ+  +  R L E
Sbjct: 369 LILFQKGQTNTPPPFEIFFCFGEEWPDRKPREKKLITVQVVPVAARLLLE 418


>gi|148833488 interferon regulatory factor 5 isoform c [Homo
           sapiens]
          Length = 488

 Score =  200 bits (508), Expect = 2e-51
 Identities = 148/410 (36%), Positives = 197/410 (48%), Gaps = 46/410 (11%)

Query: 9   RLRQWLIEQIDSSMYPGLIWENEEKSMFRIPWKHAGKQDYNQEVDASIFKAWAVFKGKFK 68
           RL+ WL+ Q++S  YPGL W N EK +F IPW+HA +   +Q+ D +IFKAWA   GK+ 
Sbjct: 16  RLKPWLVAQVNSCQYPGLQWVNGEKKLFCIPWRHATRHGPSQDGDNTIFKAWAKETGKYT 75

Query: 69  EG-DKAEPATWKTRLRCALNKSPDFEEVTDRSQLDISEPYKVYRI-----VPEEEQKCKL 122
           EG D+A+PA WK  LRCALNKS DF  + D  +    +PYK+Y +      P + Q  + 
Sbjct: 76  EGVDEADPAKWKANLRCALNKSRDFRLIYDGPRDMPPQPYKIYEVCSNGPAPTDSQPPED 135

Query: 123 GVATAGCVNEVTEMECGRS----EIDELIKEPSV--------DDYMGMIKRSPSP----- 165
               AG   E  E E  R      + E +K P             +G     PSP     
Sbjct: 136 YSFGAG-EEEEEEEELQRMLPSLSLTEDVKWPPTLQPPTLQPPVVLGPPAPDPSPLAPPP 194

Query: 166 --PEACRSQL--------LPDWWAQQPSTGVPLVTGYTTYDAHHSAFSQMVISFYYGGKL 215
             P   R  L        LP   A  P  G  L+        H    + + I F Y G+ 
Sbjct: 195 GNPAGFRELLSEVLEPGPLP---ASLPPAGEQLLPD-LLISPHMLPLTDLEIKFQYRGRP 250

Query: 216 VGQATTTCPEGCRLSLSQPGLPGT----KLYGPEGLELVRFPPADAIPSERQRQVTRKLF 271
               T + P GCRL  SQ  L  T    +L+GP  LE VRFP  + IPS++QR  T +L 
Sbjct: 251 PRALTISNPHGCRLFYSQ--LEATQEQVELFGPISLEQVRFPSPEDIPSDKQRFYTNQLL 308

Query: 272 GHLERGVLLHSSRQGVFVKRLCQGRVFCSGN-AVVCKGRPNKLERDEVVQVFDTSQFFRE 330
             L+RG++L    Q ++  RLCQ +VF SG  A      PN ++R+   ++F    F  E
Sbjct: 309 DVLDRGLILQLQGQDLYAIRLCQCKVFWSGPCASAHDSCPNPIQREVKTKLFSLEHFLNE 368

Query: 331 LQQFYNSQGRLPDG-RVVLCFGEEFPDMAPLRSKLILVQIEQLYVRQLAE 379
           L  F   Q   P    +  CFGEE+PD  P   KLI VQ+  +  R L E
Sbjct: 369 LILFQKGQTNTPPPFEIFFCFGEEWPDRKPREKKLITVQVVPVAARLLLE 418


>gi|148833494 interferon regulatory factor 5 isoform d [Homo
           sapiens]
          Length = 514

 Score =  197 bits (500), Expect = 2e-50
 Identities = 144/432 (33%), Positives = 196/432 (45%), Gaps = 64/432 (14%)

Query: 9   RLRQWLIEQIDSSMYPGLIWENEEKSMFRIPWKHAGKQDYNQEVDASIFKAWAVFKGKFK 68
           RL+ WL+ Q++S  YPGL W N EK +F IPW+HA +   +Q+ D +IFKAWA   GK+ 
Sbjct: 16  RLKPWLVAQVNSCQYPGLQWVNGEKKLFCIPWRHATRHGPSQDGDNTIFKAWAKETGKYT 75

Query: 69  EG-DKAEPATWKTRLRCALNKSPDFEEVTDRSQLDISEPYKVYRI-----VPEEEQKCKL 122
           EG D+A+PA WK  LRCALNKS DF  + D  +    +PYK+Y +      P + Q  + 
Sbjct: 76  EGVDEADPAKWKANLRCALNKSRDFRLIYDGPRDMPPQPYKIYEVCSNGPAPTDSQPPED 135

Query: 123 GVATAGCVNEVTE----MECGRSEIDELIKEPSVDDYMGMIKRSPSPPEACRSQLLPDWW 178
               AG   E  E    M    S  D +   P +  Y  ++K     P   +   L    
Sbjct: 136 YSFGAGEEEEEEEELQRMLPSLSLTDAVQSGPHMTPY-SLLKEDVKWPPTLQPPTLRPPT 194

Query: 179 AQQPSTGVPLVTGYTTYD------------------------------------------ 196
            Q P+   P+V G    D                                          
Sbjct: 195 LQPPTLQPPVVLGPPAPDPSPLAPPPGNPAGFRELLSEVLEPGPLPASLPPAGEQLLPDL 254

Query: 197 ---AHHSAFSQMVISFYYGGKLVGQATTTCPEGCRLSLSQPGLPGT----KLYGPEGLEL 249
               H    + + I F Y G+     T + P GCRL  SQ  L  T    +L+GP  LE 
Sbjct: 255 LISPHMLPLTDLEIKFQYRGRPPRALTISNPHGCRLFYSQ--LEATQEQVELFGPISLEQ 312

Query: 250 VRFPPADAIPSERQRQVTRKLFGHLERGVLLHSSRQGVFVKRLCQGRVFCSGN-AVVCKG 308
           VRFP  + IPS++QR  T +L   L+RG++L    Q ++  RLCQ +VF SG  A     
Sbjct: 313 VRFPSPEDIPSDKQRFYTNQLLDVLDRGLILQLQGQDLYAIRLCQCKVFWSGPCASAHDS 372

Query: 309 RPNKLERDEVVQVFDTSQFFRELQQFYNSQGRLPDG-RVVLCFGEEFPDMAPLRSKLILV 367
            PN ++R+   ++F    F  EL  F   Q   P    +  CFGEE+PD  P   KLI V
Sbjct: 373 CPNPIQREVKTKLFSLEHFLNELILFQKGQTNTPPPFEIFFCFGEEWPDRKPREKKLITV 432

Query: 368 QIEQLYVRQLAE 379
           Q+  +  R L E
Sbjct: 433 QVVPVAARLLLE 444


>gi|4504727 interferon regulatory factor 5 isoform a [Homo sapiens]
          Length = 504

 Score =  196 bits (499), Expect = 3e-50
 Identities = 148/425 (34%), Positives = 197/425 (46%), Gaps = 60/425 (14%)

Query: 9   RLRQWLIEQIDSSMYPGLIWENEEKSMFRIPWKHAGKQDYNQEVDASIFKAWAVFKGKFK 68
           RL+ WL+ Q++S  YPGL W N EK +F IPW+HA +   +Q+ D +IFKAWA   GK+ 
Sbjct: 16  RLKPWLVAQVNSCQYPGLQWVNGEKKLFCIPWRHATRHGPSQDGDNTIFKAWAKETGKYT 75

Query: 69  EG-DKAEPATWKTRLRCALNKSPDFEEVTDRSQLDISEPYKVYRI-----VPEEEQKCKL 122
           EG D+A+PA WK  LRCALNKS DF  + D  +    +PYK+Y +      P + Q  + 
Sbjct: 76  EGVDEADPAKWKANLRCALNKSRDFRLIYDGPRDMPPQPYKIYEVCSNGPAPTDSQPPED 135

Query: 123 GVATAGCVNEVTE----MECGRSEIDELIKEPSVDDY----------------------- 155
               AG   E  E    M    S  D +   P +  Y                       
Sbjct: 136 YSFGAGEEEEEEEELQRMLPSLSLTDAVQSGPHMTPYSLLKEDVKWPPTLQPPTLQPPVV 195

Query: 156 MGMIKRSPSP-------PEACRSQL--------LPDWWAQQPSTGVPLVTGYTTYDAHHS 200
           +G     PSP       P   R  L        LP   A  P  G  L+        H  
Sbjct: 196 LGPPAPDPSPLAPPPGNPAGFRELLSEVLEPGPLP---ASLPPAGEQLLPD-LLISPHML 251

Query: 201 AFSQMVISFYYGGKLVGQATTTCPEGCRLSLSQPGLPGT----KLYGPEGLELVRFPPAD 256
             + + I F Y G+     T + P GCRL  SQ  L  T    +L+GP  LE VRFP  +
Sbjct: 252 PLTDLEIKFQYRGRPPRALTISNPHGCRLFYSQ--LEATQEQVELFGPISLEQVRFPSPE 309

Query: 257 AIPSERQRQVTRKLFGHLERGVLLHSSRQGVFVKRLCQGRVFCSGN-AVVCKGRPNKLER 315
            IPS++QR  T +L   L+RG++L    Q ++  RLCQ +VF SG  A      PN ++R
Sbjct: 310 DIPSDKQRFYTNQLLDVLDRGLILQLQGQDLYAIRLCQCKVFWSGPCASAHDSCPNPIQR 369

Query: 316 DEVVQVFDTSQFFRELQQFYNSQGRLPDG-RVVLCFGEEFPDMAPLRSKLILVQIEQLYV 374
           +   ++F    F  EL  F   Q   P    +  CFGEE+PD  P   KLI VQ+  +  
Sbjct: 370 EVKTKLFSLEHFLNELILFQKGQTNTPPPFEIFFCFGEEWPDRKPREKKLITVQVVPVAA 429

Query: 375 RQLAE 379
           R L E
Sbjct: 430 RLLLE 434


>gi|148833496 interferon regulatory factor 5 isoform b [Homo
           sapiens]
          Length = 498

 Score =  196 bits (498), Expect = 3e-50
 Identities = 148/420 (35%), Positives = 197/420 (46%), Gaps = 56/420 (13%)

Query: 9   RLRQWLIEQIDSSMYPGLIWENEEKSMFRIPWKHAGKQDYNQEVDASIFKAWAVFKGKFK 68
           RL+ WL+ Q++S  YPGL W N EK +F IPW+HA +   +Q+ D +IFKAWA   GK+ 
Sbjct: 16  RLKPWLVAQVNSCQYPGLQWVNGEKKLFCIPWRHATRHGPSQDGDNTIFKAWAKETGKYT 75

Query: 69  EG-DKAEPATWKTRLRCALNKSPDFEEVTDRSQLDISEPYKVYRI-----VPEEEQKCKL 122
           EG D+A+PA WK  LRCALNKS DF  + D  +    +PYK+Y +      P + Q  + 
Sbjct: 76  EGVDEADPAKWKANLRCALNKSRDFRLIYDGPRDMPPQPYKIYEVCSNGPAPTDSQPPED 135

Query: 123 GVATAGCVNEVTEMECGRS----EIDELIKEPSV------------------DDYMGMIK 160
               AG   E  E E  R      + E +K P                       +G   
Sbjct: 136 YSFGAG-EEEEEEEELQRMLPSLSLTEDVKWPPTLQPPTLRPPTLQPPTLQPPVVLGPPA 194

Query: 161 RSPSP-------PEACRSQL--------LPDWWAQQPSTGVPLVTGYTTYDAHHSAFSQM 205
             PSP       P   R  L        LP   A  P  G  L+        H    + +
Sbjct: 195 PDPSPLAPPPGNPAGFRELLSEVLEPGPLP---ASLPPAGEQLLPD-LLISPHMLPLTDL 250

Query: 206 VISFYYGGKLVGQATTTCPEGCRLSLSQPGLPGT----KLYGPEGLELVRFPPADAIPSE 261
            I F Y G+     T + P GCRL  SQ  L  T    +L+GP  LE VRFP  + IPS+
Sbjct: 251 EIKFQYRGRPPRALTISNPHGCRLFYSQ--LEATQEQVELFGPISLEQVRFPSPEDIPSD 308

Query: 262 RQRQVTRKLFGHLERGVLLHSSRQGVFVKRLCQGRVFCSGN-AVVCKGRPNKLERDEVVQ 320
           +QR  T +L   L+RG++L    Q ++  RLCQ +VF SG  A      PN ++R+   +
Sbjct: 309 KQRFYTNQLLDVLDRGLILQLQGQDLYAIRLCQCKVFWSGPCASAHDSCPNPIQREVKTK 368

Query: 321 VFDTSQFFRELQQFYNSQGRLPDG-RVVLCFGEEFPDMAPLRSKLILVQIEQLYVRQLAE 379
           +F    F  EL  F   Q   P    +  CFGEE+PD  P   KLI VQ+  +  R L E
Sbjct: 369 LFSLEHFLNELILFQKGQTNTPPPFEIFFCFGEEWPDRKPREKKLITVQVVPVAARLLLE 428


>gi|14249182 interferon regulatory factor 5 isoform b [Homo sapiens]
          Length = 498

 Score =  196 bits (498), Expect = 3e-50
 Identities = 148/420 (35%), Positives = 197/420 (46%), Gaps = 56/420 (13%)

Query: 9   RLRQWLIEQIDSSMYPGLIWENEEKSMFRIPWKHAGKQDYNQEVDASIFKAWAVFKGKFK 68
           RL+ WL+ Q++S  YPGL W N EK +F IPW+HA +   +Q+ D +IFKAWA   GK+ 
Sbjct: 16  RLKPWLVAQVNSCQYPGLQWVNGEKKLFCIPWRHATRHGPSQDGDNTIFKAWAKETGKYT 75

Query: 69  EG-DKAEPATWKTRLRCALNKSPDFEEVTDRSQLDISEPYKVYRI-----VPEEEQKCKL 122
           EG D+A+PA WK  LRCALNKS DF  + D  +    +PYK+Y +      P + Q  + 
Sbjct: 76  EGVDEADPAKWKANLRCALNKSRDFRLIYDGPRDMPPQPYKIYEVCSNGPAPTDSQPPED 135

Query: 123 GVATAGCVNEVTEMECGRS----EIDELIKEPSV------------------DDYMGMIK 160
               AG   E  E E  R      + E +K P                       +G   
Sbjct: 136 YSFGAG-EEEEEEEELQRMLPSLSLTEDVKWPPTLQPPTLRPPTLQPPTLQPPVVLGPPA 194

Query: 161 RSPSP-------PEACRSQL--------LPDWWAQQPSTGVPLVTGYTTYDAHHSAFSQM 205
             PSP       P   R  L        LP   A  P  G  L+        H    + +
Sbjct: 195 PDPSPLAPPPGNPAGFRELLSEVLEPGPLP---ASLPPAGEQLLPD-LLISPHMLPLTDL 250

Query: 206 VISFYYGGKLVGQATTTCPEGCRLSLSQPGLPGT----KLYGPEGLELVRFPPADAIPSE 261
            I F Y G+     T + P GCRL  SQ  L  T    +L+GP  LE VRFP  + IPS+
Sbjct: 251 EIKFQYRGRPPRALTISNPHGCRLFYSQ--LEATQEQVELFGPISLEQVRFPSPEDIPSD 308

Query: 262 RQRQVTRKLFGHLERGVLLHSSRQGVFVKRLCQGRVFCSGN-AVVCKGRPNKLERDEVVQ 320
           +QR  T +L   L+RG++L    Q ++  RLCQ +VF SG  A      PN ++R+   +
Sbjct: 309 KQRFYTNQLLDVLDRGLILQLQGQDLYAIRLCQCKVFWSGPCASAHDSCPNPIQREVKTK 368

Query: 321 VFDTSQFFRELQQFYNSQGRLPDG-RVVLCFGEEFPDMAPLRSKLILVQIEQLYVRQLAE 379
           +F    F  EL  F   Q   P    +  CFGEE+PD  P   KLI VQ+  +  R L E
Sbjct: 369 LFSLEHFLNELILFQKGQTNTPPPFEIFFCFGEEWPDRKPREKKLITVQVVPVAARLLLE 428


>gi|4504725 interferon regulatory factor 3 [Homo sapiens]
          Length = 427

 Score =  129 bits (323), Expect = 7e-30
 Identities = 109/400 (27%), Positives = 172/400 (43%), Gaps = 54/400 (13%)

Query: 9   RLRQWLIEQIDSSMYPGLIWENEEKSMFRIPWKHAGKQDYNQEVDASIFKAWAVFKGKFK 68
           R+  WL+ Q+D     G+ W N+ ++ FRIPWKH  +QD  QE D  IF+AWA   G + 
Sbjct: 7   RILPWLVSQLDLGQLEGVAWVNKSRTRFRIPWKHGLRQDAQQE-DFGIFQAWAEATGAYV 65

Query: 69  EG-DKAEPATWKTRLRCALNKSPDFEEVTDRSQLDISEPYKVYRIVPEEEQKCKLGVATA 127
            G DK +  TWK   R ALN+        DRS+ D  +P+K+Y  V         GV   
Sbjct: 66  PGRDKPDLPTWKRNFRSALNRKEGLRLAEDRSK-DPHDPHKIYEFV-------NSGVGDF 117

Query: 128 GCVNEVTEMECGRSEIDELIKEPSVDDYMGMIKRSPSP----------PEACRSQLLPDW 177
              +   +   G S  D   +E  +D+ +G +  +P P          PE C   L    
Sbjct: 118 SQPDTSPDTNGGGSTSD--TQEDILDELLGNMVLAPLPDPGPPSLAVAPEPCPQPL---- 171

Query: 178 WAQQPSTGVPLVTGYTTYDAHHSAFSQMV---------ISFYYGGKLVGQATTTCPEGCR 228
             + PS   P  T +       +   +++         ++ +Y G+ V Q T +CPEG R
Sbjct: 172 --RSPSLDNP--TPFPNLGPSENPLKRLLVPGEEWEFEVTAFYRGRQVFQQTISCPEGLR 227

Query: 229 LSLSQPG---LPGTKLYGPEGLELVRFPPADAIPSERQRQVTRKLFGHLERGVLLHSSRQ 285
           L  S+ G   LPG  +  P+        P  ++         R +   L  G+ L  + Q
Sbjct: 228 LVGSEVGDRTLPGWPVTLPD--------PGMSLTDRGVMSYVRHVLSCLGGGLALWRAGQ 279

Query: 286 GVFVKRLCQGRVFCSGNAVVC----KGRPNKLERDEVVQVFDTSQFFRELQQFYNSQGRL 341
            ++ +RL     + + +  +      G   ++ +D+   VFD   F  +L  F    GR 
Sbjct: 280 WLWAQRLGHCHTYWAVSEELLPNSGHGPDGEVPKDKEGGVFDLGPFIVDLITFTEGSGRS 339

Query: 342 PDGRVVLCFGEEFPDMAPLRSKLILVQIEQLYVRQLAEEA 381
           P   +  C GE +P   P   +L++V++    +R L E A
Sbjct: 340 PRYALWFCVGESWPQDQPWTKRLVMVKVVPTCLRALVEMA 379


>gi|4504721 interferon regulatory factor 1 [Homo sapiens]
          Length = 325

 Score =  118 bits (295), Expect = 1e-26
 Identities = 56/140 (40%), Positives = 87/140 (62%), Gaps = 4/140 (2%)

Query: 9   RLRQWLIEQIDSSMYPGLIWENEEKSMFRIPWKHAGKQDYNQEVDASIFKAWAVFKGKFK 68
           R+R WL  QI+S+  PGLIW N+E+ +F+IPWKHA K  ++   DA +F++WA+  G++K
Sbjct: 7   RMRPWLEMQINSNQIPGLIWINKEEMIFQIPWKHAAKHGWDINKDACLFRSWAIHTGRYK 66

Query: 69  EGDK-AEPATWKTRLRCALNKSPDFEEVTDRSQLDISEPYKVYRIVP---EEEQKCKLGV 124
            G+K  +P TWK   RCA+N  PD EEV D+S+   S   +VYR++P   + ++K +   
Sbjct: 67  AGEKEPDPKTWKANFRCAMNSLPDIEEVKDQSRNKGSSAVRVYRMLPPLTKNQRKERKSK 126

Query: 125 ATAGCVNEVTEMECGRSEID 144
           ++    ++     CG S  D
Sbjct: 127 SSRDAKSKAKRKSCGDSSPD 146


>gi|153082752 interferon regulatory factor 2 [Homo sapiens]
          Length = 349

 Score =  117 bits (294), Expect = 2e-26
 Identities = 54/116 (46%), Positives = 76/116 (65%), Gaps = 1/116 (0%)

Query: 9   RLRQWLIEQIDSSMYPGLIWENEEKSMFRIPWKHAGKQDYNQEVDASIFKAWAVFKGKFK 68
           R+R WL EQI+S+  PGL W N+EK +F+IPW HA +  ++ E DA +F+ WA+  GK +
Sbjct: 7   RMRPWLEEQINSNTIPGLKWLNKEKKIFQIPWMHAARHGWDVEKDAPLFRNWAIHTGKHQ 66

Query: 69  EG-DKAEPATWKTRLRCALNKSPDFEEVTDRSQLDISEPYKVYRIVPEEEQKCKLG 123
            G DK +P TWK   RCA+N  PD EEV D+S    +  ++VYR++P  E+  K G
Sbjct: 67  PGVDKPDPKTWKANFRCAMNSLPDIEEVKDKSIKKGNNAFRVYRMLPLSERPSKKG 122


>gi|98985819 interferon regulatory factor 7 isoform d [Homo sapiens]
          Length = 516

 Score = 89.0 bits (219), Expect = 8e-18
 Identities = 47/114 (41%), Positives = 67/114 (58%), Gaps = 12/114 (10%)

Query: 12  QWLIEQIDSSMYPGLIWENEEKSMFRIPWKHAGKQDYNQEVDASIFKAWAVFKGKF---- 67
           +WL+ +I S  Y GL W +E ++ FR+PWKH  ++D + E DA IFKAWAV +G++    
Sbjct: 29  EWLLGEISSGCYEGLQWLDEARTCFRVPWKHFARKDLS-EADARIFKAWAVARGRWPPSS 87

Query: 68  ------KEGDKAEPATWKTRLRCALNKSPDFEEVTDRSQLDISEPYKVYRIVPE 115
                  E + AE A WKT  RCAL  +  F  + D S  D ++P+KVY +  E
Sbjct: 88  RGGGPPPEAETAERAGWKTNFRCALRSTRRFVMLRDNSG-DPADPHKVYALSRE 140



 Score = 46.6 bits (109), Expect = 4e-05
 Identities = 42/169 (24%), Positives = 72/169 (42%), Gaps = 10/169 (5%)

Query: 207 ISFYYGGKLVGQATTTCPEGCRLSLSQPGLPGTKLYGPEGLELVRFPPADAIPSERQRQV 266
           ++  Y G+ V Q     P  C      P  P  +   P+    V FP    +P ++Q + 
Sbjct: 304 VTIMYKGRTVLQKVVGHPS-CTFLYGPPD-PAVRATDPQQ---VAFPSPAELPDQKQLRY 358

Query: 267 TRKLFGHLERGVLLHSSRQGVFVKRLCQGRVFCSGNAVVCKGRPNK----LERDEVVQVF 322
           T +L  H+  G+ L      ++ +R+ + +V+           P+     L R+    +F
Sbjct: 359 TEELLRHVAPGLHLELRGPQLWARRMGKCKVYWEVGGPPGSASPSTPACLLPRNCDTPIF 418

Query: 323 DTSQFFRELQQFYNSQGR-LPDGRVVLCFGEEFPDMAPLRSKLILVQIE 370
           D   FF+EL +F   Q R  P   + L FG++     P    L+LV++E
Sbjct: 419 DFRVFFQELVEFRARQRRGSPRYTIYLGFGQDLSAGRPKEKSLVLVKLE 467


>gi|4758610 interferon regulatory factor 7 isoform a [Homo sapiens]
          Length = 503

 Score = 89.0 bits (219), Expect = 8e-18
 Identities = 47/114 (41%), Positives = 67/114 (58%), Gaps = 12/114 (10%)

Query: 12  QWLIEQIDSSMYPGLIWENEEKSMFRIPWKHAGKQDYNQEVDASIFKAWAVFKGKF---- 67
           +WL+ +I S  Y GL W +E ++ FR+PWKH  ++D + E DA IFKAWAV +G++    
Sbjct: 16  EWLLGEISSGCYEGLQWLDEARTCFRVPWKHFARKDLS-EADARIFKAWAVARGRWPPSS 74

Query: 68  ------KEGDKAEPATWKTRLRCALNKSPDFEEVTDRSQLDISEPYKVYRIVPE 115
                  E + AE A WKT  RCAL  +  F  + D S  D ++P+KVY +  E
Sbjct: 75  RGGGPPPEAETAERAGWKTNFRCALRSTRRFVMLRDNSG-DPADPHKVYALSRE 127



 Score = 46.6 bits (109), Expect = 4e-05
 Identities = 42/169 (24%), Positives = 72/169 (42%), Gaps = 10/169 (5%)

Query: 207 ISFYYGGKLVGQATTTCPEGCRLSLSQPGLPGTKLYGPEGLELVRFPPADAIPSERQRQV 266
           ++  Y G+ V Q     P  C      P  P  +   P+    V FP    +P ++Q + 
Sbjct: 291 VTIMYKGRTVLQKVVGHPS-CTFLYGPPD-PAVRATDPQQ---VAFPSPAELPDQKQLRY 345

Query: 267 TRKLFGHLERGVLLHSSRQGVFVKRLCQGRVFCSGNAVVCKGRPNK----LERDEVVQVF 322
           T +L  H+  G+ L      ++ +R+ + +V+           P+     L R+    +F
Sbjct: 346 TEELLRHVAPGLHLELRGPQLWARRMGKCKVYWEVGGPPGSASPSTPACLLPRNCDTPIF 405

Query: 323 DTSQFFRELQQFYNSQGR-LPDGRVVLCFGEEFPDMAPLRSKLILVQIE 370
           D   FF+EL +F   Q R  P   + L FG++     P    L+LV++E
Sbjct: 406 DFRVFFQELVEFRARQRRGSPRYTIYLGFGQDLSAGRPKEKSLVLVKLE 454


>gi|4809284 interferon regulatory factor 7 isoform b [Homo sapiens]
          Length = 474

 Score = 89.0 bits (219), Expect = 8e-18
 Identities = 47/114 (41%), Positives = 67/114 (58%), Gaps = 12/114 (10%)

Query: 12  QWLIEQIDSSMYPGLIWENEEKSMFRIPWKHAGKQDYNQEVDASIFKAWAVFKGKF---- 67
           +WL+ +I S  Y GL W +E ++ FR+PWKH  ++D + E DA IFKAWAV +G++    
Sbjct: 16  EWLLGEISSGCYEGLQWLDEARTCFRVPWKHFARKDLS-EADARIFKAWAVARGRWPPSS 74

Query: 68  ------KEGDKAEPATWKTRLRCALNKSPDFEEVTDRSQLDISEPYKVYRIVPE 115
                  E + AE A WKT  RCAL  +  F  + D S  D ++P+KVY +  E
Sbjct: 75  RGGGPPPEAETAERAGWKTNFRCALRSTRRFVMLRDNSG-DPADPHKVYALSRE 127



 Score = 46.6 bits (109), Expect = 4e-05
 Identities = 42/169 (24%), Positives = 72/169 (42%), Gaps = 10/169 (5%)

Query: 207 ISFYYGGKLVGQATTTCPEGCRLSLSQPGLPGTKLYGPEGLELVRFPPADAIPSERQRQV 266
           ++  Y G+ V Q     P  C      P  P  +   P+    V FP    +P ++Q + 
Sbjct: 262 VTIMYKGRTVLQKVVGHPS-CTFLYGPPD-PAVRATDPQQ---VAFPSPAELPDQKQLRY 316

Query: 267 TRKLFGHLERGVLLHSSRQGVFVKRLCQGRVFCSGNAVVCKGRPNK----LERDEVVQVF 322
           T +L  H+  G+ L      ++ +R+ + +V+           P+     L R+    +F
Sbjct: 317 TEELLRHVAPGLHLELRGPQLWARRMGKCKVYWEVGGPPGSASPSTPACLLPRNCDTPIF 376

Query: 323 DTSQFFRELQQFYNSQGR-LPDGRVVLCFGEEFPDMAPLRSKLILVQIE 370
           D   FF+EL +F   Q R  P   + L FG++     P    L+LV++E
Sbjct: 377 DFRVFFQELVEFRARQRRGSPRYTIYLGFGQDLSAGRPKEKSLVLVKLE 425


>gi|239757474 PREDICTED: similar to hCG1785205 [Homo sapiens]
          Length = 362

 Score = 57.4 bits (137), Expect = 2e-08
 Identities = 28/58 (48%), Positives = 33/58 (56%), Gaps = 9/58 (15%)

Query: 17 QIDSSMYPGLIWENEEKSMFRIPWKHAGKQDYNQEVDASIFKAWAVFKGKFKEGDKAE 74
          QI+S  Y GL WE+  K++FRIPWKH  KQ Y         +AW V KGK  EG   E
Sbjct: 16 QIESGCYVGLCWEDAGKTLFRIPWKHVAKQGY---------QAWMVHKGKHLEGTNKE 64


>gi|239751984 PREDICTED: similar to hCG1785205 [Homo sapiens]
          Length = 362

 Score = 57.4 bits (137), Expect = 2e-08
 Identities = 28/58 (48%), Positives = 33/58 (56%), Gaps = 9/58 (15%)

Query: 17 QIDSSMYPGLIWENEEKSMFRIPWKHAGKQDYNQEVDASIFKAWAVFKGKFKEGDKAE 74
          QI+S  Y GL WE+  K++FRIPWKH  KQ Y         +AW V KGK  EG   E
Sbjct: 16 QIESGCYVGLCWEDAGKTLFRIPWKHVAKQGY---------QAWMVHKGKHLEGTNKE 64


>gi|239746471 PREDICTED: hypothetical protein XP_002343764 [Homo
          sapiens]
          Length = 362

 Score = 57.4 bits (137), Expect = 2e-08
 Identities = 28/58 (48%), Positives = 33/58 (56%), Gaps = 9/58 (15%)

Query: 17 QIDSSMYPGLIWENEEKSMFRIPWKHAGKQDYNQEVDASIFKAWAVFKGKFKEGDKAE 74
          QI+S  Y GL WE+  K++FRIPWKH  KQ Y         +AW V KGK  EG   E
Sbjct: 16 QIESGCYVGLCWEDAGKTLFRIPWKHVAKQGY---------QAWMVHKGKHLEGTNKE 64


>gi|32967601 ankyrin 3 isoform 1 [Homo sapiens]
          Length = 4377

 Score = 31.6 bits (70), Expect = 1.4
 Identities = 31/151 (20%), Positives = 67/151 (44%), Gaps = 16/151 (10%)

Query: 235  GLPGTKLYGPE--GLELVRFPPADAIPSERQRQVTRKLFG------HLERGVLLH----- 281
            G P ++L G +    E +   P   I S+  + V+    G      H ++  +LH     
Sbjct: 2489 GPPSSELQGSDKRSREKIATAPKKEILSKIYKDVSENGVGKVSKDEHFDKVTVLHYSGNV 2548

Query: 282  SSRQGVFVKRLCQGRVFCSGNAVVCKGRPNKLERDEVVQVFDTSQFFRELQQFYNSQGRL 341
            SS +     R  + R+      ++ + R ++  ++   ++ + SQFFR+  +  N + + 
Sbjct: 2549 SSPKHAMWMRFTEDRLDRGREKLIYEDRVDRTVKEAEEKLTEVSQFFRDKTEKLNDELQS 2608

Query: 342  PDGRVVLCFGEEFPDMAPLRS---KLILVQI 369
            P+ +     G+E+   +P  S   K++L ++
Sbjct: 2609 PEKKARPKNGKEYSSQSPTSSSPEKVLLTEL 2639


>gi|14149680 extended synaptotagmin-like protein 1 [Homo sapiens]
          Length = 1104

 Score = 31.2 bits (69), Expect = 1.9
 Identities = 24/90 (26%), Positives = 41/90 (45%), Gaps = 13/90 (14%)

Query: 104 SEPYKVYRI--------VPEEEQKCKLGVATAGCVNEVTEMECGRSEIDELIKEPSVDDY 155
           S+PY + R+        V +EE   + G      V+EV   E    E++   K+P  DD+
Sbjct: 356 SDPYALVRLGTQTFCSRVIDEELNPQWGETYEVMVHEVPGQEI---EVEVFDKDPDKDDF 412

Query: 156 MGMIKRSPSPPEACRSQLLPDWWAQQPSTG 185
           +G +K      +  ++ +L DW+  Q   G
Sbjct: 413 LGRMKLDVG--KVLQASVLDDWFPLQGGQG 440


>gi|9256590 protocadherin alpha 5 isoform 1 precursor [Homo sapiens]
          Length = 936

 Score = 30.8 bits (68), Expect = 2.4
 Identities = 25/80 (31%), Positives = 42/80 (52%), Gaps = 7/80 (8%)

Query: 273 HLERGVLLHSSRQGVFVKRLCQGRVFCSGNAVVCKGRPNKLERDEVVQVFDTS----QFF 328
           +L+ G+L  +SR  +  + LC+ R  CS +  V   RP ++   EV  V D +    +F 
Sbjct: 77  NLQNGILFVNSR--IDREELCRRRAECSIHLEVIVDRPLQVFHVEVA-VKDINDNPPRFS 133

Query: 329 RELQQFYNSQGRLPDGRVVL 348
           R+ Q+ +  + R+PD R  L
Sbjct: 134 RQEQRLFILESRMPDSRFPL 153


>gi|14165416 protocadherin alpha 5 isoform 2 precursor [Homo
           sapiens]
          Length = 816

 Score = 30.8 bits (68), Expect = 2.4
 Identities = 25/80 (31%), Positives = 42/80 (52%), Gaps = 7/80 (8%)

Query: 273 HLERGVLLHSSRQGVFVKRLCQGRVFCSGNAVVCKGRPNKLERDEVVQVFDTS----QFF 328
           +L+ G+L  +SR  +  + LC+ R  CS +  V   RP ++   EV  V D +    +F 
Sbjct: 77  NLQNGILFVNSR--IDREELCRRRAECSIHLEVIVDRPLQVFHVEVA-VKDINDNPPRFS 133

Query: 329 RELQQFYNSQGRLPDGRVVL 348
           R+ Q+ +  + R+PD R  L
Sbjct: 134 RQEQRLFILESRMPDSRFPL 153


>gi|25777608 NLR family member X1 isoform 1 [Homo sapiens]
          Length = 975

 Score = 30.0 bits (66), Expect = 4.2
 Identities = 16/52 (30%), Positives = 27/52 (51%), Gaps = 5/52 (9%)

Query: 370 EQLYVRQLAEEAGKSC-GAGSVMQAPEEPPPDQVFRMFP----DICASHQRS 416
           E  Y   + ++ G S  G     + P+EPP D+VF +FP     + ++H R+
Sbjct: 586 EDYYNDDVLDQMGASILGVEGPRRHPDEPPEDEVFELFPMFMGGLLSAHNRA 637


>gi|25777610 NLR family member X1 isoform 2 [Homo sapiens]
          Length = 921

 Score = 30.0 bits (66), Expect = 4.2
 Identities = 16/52 (30%), Positives = 27/52 (51%), Gaps = 5/52 (9%)

Query: 370 EQLYVRQLAEEAGKSC-GAGSVMQAPEEPPPDQVFRMFP----DICASHQRS 416
           E  Y   + ++ G S  G     + P+EPP D+VF +FP     + ++H R+
Sbjct: 586 EDYYNDDVLDQMGASILGVEGPRRHPDEPPEDEVFELFPMFMGGLLSAHNRA 637


>gi|157364934 fibrosin [Homo sapiens]
          Length = 460

 Score = 30.0 bits (66), Expect = 4.2
 Identities = 18/72 (25%), Positives = 25/72 (34%), Gaps = 5/72 (6%)

Query: 116 EEQKCKLGVATAGCVNEVTEMECGRSEIDELIKEPSVDDYMGMIKRSPSPPEACRSQLLP 175
           +E+      A A           G   +  L + P    ++G     PSPP+ C   L P
Sbjct: 308 KEEAAAAAAAAAAAAAAAAAAATGPQGLHLLFERPRPPPFLG-----PSPPDRCAGFLEP 362

Query: 176 DWWAQQPSTGVP 187
            W A  P    P
Sbjct: 363 TWLAAPPRLARP 374


>gi|49355778 inter-alpha trypsin inhibitor heavy chain precursor 5
           isoform 3 [Homo sapiens]
          Length = 702

 Score = 29.6 bits (65), Expect = 5.5
 Identities = 19/51 (37%), Positives = 24/51 (47%)

Query: 18  IDSSMYPGLIWENEEKSMFRIPWKHAGKQDYNQEVDASIFKAWAVFKGKFK 68
           I   +Y G I E E+KS  R+  K     + N E    IF+A AV   K K
Sbjct: 102 IGDKVYQGEITEREKKSGDRVKEKRNKTTEENGEKGTEIFRASAVIPSKDK 152


>gi|153945780 inter-alpha trypsin inhibitor heavy chain precursor 5
           isoform 1 [Homo sapiens]
          Length = 956

 Score = 29.6 bits (65), Expect = 5.5
 Identities = 19/51 (37%), Positives = 24/51 (47%)

Query: 18  IDSSMYPGLIWENEEKSMFRIPWKHAGKQDYNQEVDASIFKAWAVFKGKFK 68
           I   +Y G I E E+KS  R+  K     + N E    IF+A AV   K K
Sbjct: 102 IGDKVYQGEITEREKKSGDRVKEKRNKTTEENGEKGTEIFRASAVIPSKDK 152


>gi|166235140 seizure related 6 homolog (mouse)-like 2 isoform 4
           [Homo sapiens]
          Length = 809

 Score = 29.3 bits (64), Expect = 7.1
 Identities = 15/42 (35%), Positives = 20/42 (47%)

Query: 185 GVPLVTGYTTYDAHHSAFSQMVISFYYGGKLVGQATTTCPEG 226
           GVP     T Y  H+ A   +    Y G +L+G+ T TC  G
Sbjct: 661 GVPENGYQTLYKHHYQAGESLRFFCYEGFELIGEVTITCVPG 702


  Database: hs.faa
    Posted date:  Aug 4, 2009  4:42 PM
  Number of letters in database: 18,247,518
  Number of sequences in database:  37,866
  
Lambda     K      H
   0.320    0.136    0.423 

Gapped
Lambda     K      H
   0.267   0.0410    0.140 


Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Hits to DB: 18,839,253
Number of Sequences: 37866
Number of extensions: 906628
Number of successful extensions: 2239
Number of sequences better than 10.0: 30
Number of HSP's better than 10.0 without gapping: 27
Number of HSP's successfully gapped in prelim test: 9
Number of HSP's that attempted gapping in prelim test: 2147
Number of HSP's gapped (non-prelim): 55
length of query: 426
length of database: 18,247,518
effective HSP length: 105
effective length of query: 321
effective length of database: 14,271,588
effective search space: 4581179748
effective search space used: 4581179748
T: 11
A: 40
X1: 16 ( 7.4 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 41 (21.8 bits)
S2: 63 (28.9 bits)

Search results were obtained with NCBI BLAST and RefSeq entries.


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Guide to the Human Genome
Copyright © 2010 by Stewart Scherer. All rights reserved.

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