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Search of human proteins with 4503943
BLASTP 2.2.11 [Jun-05-2005]
Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer,
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997),
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs", Nucleic Acids Res. 25:3389-3402.
Query= gi|4503943 glutaryl-Coenzyme A dehydrogenase isoform a
precursor [Homo sapiens]
(438 letters)
Database: hs.faa
37,866 sequences; 18,247,518 total letters
Searching..................................................done
Score E
Sequences producing significant alignments: (bits) Value
gi|4503943 glutaryl-Coenzyme A dehydrogenase isoform a precursor... 877 0.0
gi|7669494 glutaryl-Coenzyme A dehydrogenase isoform b precursor... 830 0.0
gi|4557233 short-chain acyl-CoA dehydrogenase precursor [Homo sa... 175 8e-44
gi|226958412 isovaleryl Coenzyme A dehydrogenase isoform 1 [Homo... 160 3e-39
gi|4501859 acyl-Coenzyme A dehydrogenase, short/branched chain p... 155 5e-38
gi|226958414 isovaleryl Coenzyme A dehydrogenase isoform 2 [Homo... 148 8e-36
gi|4557235 acyl-Coenzyme A dehydrogenase, very long chain isofor... 148 8e-36
gi|76496475 acyl-Coenzyme A dehydrogenase, very long chain isofo... 148 8e-36
gi|21361497 acyl-Coenzyme A dehydrogenase family, member 9 [Homo... 142 8e-34
gi|187960098 medium-chain acyl-CoA dehydrogenase isoform b precu... 140 2e-33
gi|4557231 medium-chain acyl-CoA dehydrogenase isoform a precurs... 140 2e-33
gi|4501857 long-chain acyl-CoA dehydrogenase precursor [Homo sap... 123 4e-28
gi|7656849 acyl-Coenzyme A dehydrogenase family, member 8 [Homo ... 121 1e-27
gi|211971008 acyl-Coenzyme A dehydrogenase family, member 10 iso... 71 2e-12
gi|48976061 acyl-Coenzyme A dehydrogenase family, member 10 isof... 71 2e-12
gi|157502163 acyl-Coenzyme A oxidase-like 2 [Homo sapiens] 60 4e-09
gi|38505218 putative acyl-CoA dehydrogenase [Homo sapiens] 59 9e-09
gi|218563754 acyl-Coenzyme A oxidase-like 3 [Homo sapiens] 52 1e-06
gi|218563752 acyl-Coenzyme A oxidase-like 1 [Homo sapiens] 52 1e-06
gi|156104866 acyl-Coenzyme A oxidase 3 isoform b [Homo sapiens] 48 2e-05
gi|156104864 acyl-Coenzyme A oxidase 3 isoform a [Homo sapiens] 48 2e-05
gi|211971012 acyl-Coenzyme A dehydrogenase family, member 10 iso... 46 6e-05
gi|4501869 acyl-Coenzyme A oxidase 2 [Homo sapiens] 39 0.009
gi|21361458 Rho guanine nucleotide exchange factor (GEF) 17 [Hom... 37 0.046
gi|30089974 acyl-Coenzyme A oxidase 1 isoform b [Homo sapiens] 35 0.18
gi|30089972 acyl-Coenzyme A oxidase 1 isoform a [Homo sapiens] 34 0.30
gi|30410846 APG4 autophagy 4 homolog C isoform 8 [Homo sapiens] 32 0.87
gi|30410844 APG4 autophagy 4 homolog C isoform 7 [Homo sapiens] 32 0.87
gi|163310725 ER degradation enhancer, mannosidase alpha-like 3 [... 32 1.1
gi|7657104 G0/G1switch 2 [Homo sapiens] 32 1.5
>gi|4503943 glutaryl-Coenzyme A dehydrogenase isoform a precursor
[Homo sapiens]
Length = 438
Score = 877 bits (2265), Expect = 0.0
Identities = 438/438 (100%), Positives = 438/438 (100%)
Query: 1 MALRGVSVRLLSRGPGLHVLRTWVSSAAQTEKGGRTQSQLAKSSRPEFDWQDPLVLEEQL 60
MALRGVSVRLLSRGPGLHVLRTWVSSAAQTEKGGRTQSQLAKSSRPEFDWQDPLVLEEQL
Sbjct: 1 MALRGVSVRLLSRGPGLHVLRTWVSSAAQTEKGGRTQSQLAKSSRPEFDWQDPLVLEEQL 60
Query: 61 TTDEILIRDTFRTYCQERLMPRILLANRNEVFHREIISEMGELGVLGPTIKGYGCAGVSS 120
TTDEILIRDTFRTYCQERLMPRILLANRNEVFHREIISEMGELGVLGPTIKGYGCAGVSS
Sbjct: 61 TTDEILIRDTFRTYCQERLMPRILLANRNEVFHREIISEMGELGVLGPTIKGYGCAGVSS 120
Query: 121 VAYGLLARELERVDSGYRSAMSVQSSLVMHPIYAYGSEEQRQKYLPQLAKGELLGCFGLT 180
VAYGLLARELERVDSGYRSAMSVQSSLVMHPIYAYGSEEQRQKYLPQLAKGELLGCFGLT
Sbjct: 121 VAYGLLARELERVDSGYRSAMSVQSSLVMHPIYAYGSEEQRQKYLPQLAKGELLGCFGLT 180
Query: 181 EPNSGSDPSSMETRAHYNSSNKSYTLNGTKTWITNSPMADLFVVWARCEDGCIRGFLLEK 240
EPNSGSDPSSMETRAHYNSSNKSYTLNGTKTWITNSPMADLFVVWARCEDGCIRGFLLEK
Sbjct: 181 EPNSGSDPSSMETRAHYNSSNKSYTLNGTKTWITNSPMADLFVVWARCEDGCIRGFLLEK 240
Query: 241 GMRGLSAPRIQGKFSLRASATGMIIMDGVEVPEENVLPGASSLGGPFGCLNNARYGIAWG 300
GMRGLSAPRIQGKFSLRASATGMIIMDGVEVPEENVLPGASSLGGPFGCLNNARYGIAWG
Sbjct: 241 GMRGLSAPRIQGKFSLRASATGMIIMDGVEVPEENVLPGASSLGGPFGCLNNARYGIAWG 300
Query: 301 VLGASEFCLHTARQYALDRMQFGVPLARNQLIQKKLADMLTEITLGLHACLQLGRLKDQD 360
VLGASEFCLHTARQYALDRMQFGVPLARNQLIQKKLADMLTEITLGLHACLQLGRLKDQD
Sbjct: 301 VLGASEFCLHTARQYALDRMQFGVPLARNQLIQKKLADMLTEITLGLHACLQLGRLKDQD 360
Query: 361 KAAPEMVSLLKRNNCGKALDIARQARDMLGGNGISDEYHVIRHAMNLEAVNTYEGTHDIH 420
KAAPEMVSLLKRNNCGKALDIARQARDMLGGNGISDEYHVIRHAMNLEAVNTYEGTHDIH
Sbjct: 361 KAAPEMVSLLKRNNCGKALDIARQARDMLGGNGISDEYHVIRHAMNLEAVNTYEGTHDIH 420
Query: 421 ALILGRAITGIQAFTASK 438
ALILGRAITGIQAFTASK
Sbjct: 421 ALILGRAITGIQAFTASK 438
>gi|7669494 glutaryl-Coenzyme A dehydrogenase isoform b precursor
[Homo sapiens]
Length = 428
Score = 830 bits (2145), Expect = 0.0
Identities = 414/414 (100%), Positives = 414/414 (100%)
Query: 1 MALRGVSVRLLSRGPGLHVLRTWVSSAAQTEKGGRTQSQLAKSSRPEFDWQDPLVLEEQL 60
MALRGVSVRLLSRGPGLHVLRTWVSSAAQTEKGGRTQSQLAKSSRPEFDWQDPLVLEEQL
Sbjct: 1 MALRGVSVRLLSRGPGLHVLRTWVSSAAQTEKGGRTQSQLAKSSRPEFDWQDPLVLEEQL 60
Query: 61 TTDEILIRDTFRTYCQERLMPRILLANRNEVFHREIISEMGELGVLGPTIKGYGCAGVSS 120
TTDEILIRDTFRTYCQERLMPRILLANRNEVFHREIISEMGELGVLGPTIKGYGCAGVSS
Sbjct: 61 TTDEILIRDTFRTYCQERLMPRILLANRNEVFHREIISEMGELGVLGPTIKGYGCAGVSS 120
Query: 121 VAYGLLARELERVDSGYRSAMSVQSSLVMHPIYAYGSEEQRQKYLPQLAKGELLGCFGLT 180
VAYGLLARELERVDSGYRSAMSVQSSLVMHPIYAYGSEEQRQKYLPQLAKGELLGCFGLT
Sbjct: 121 VAYGLLARELERVDSGYRSAMSVQSSLVMHPIYAYGSEEQRQKYLPQLAKGELLGCFGLT 180
Query: 181 EPNSGSDPSSMETRAHYNSSNKSYTLNGTKTWITNSPMADLFVVWARCEDGCIRGFLLEK 240
EPNSGSDPSSMETRAHYNSSNKSYTLNGTKTWITNSPMADLFVVWARCEDGCIRGFLLEK
Sbjct: 181 EPNSGSDPSSMETRAHYNSSNKSYTLNGTKTWITNSPMADLFVVWARCEDGCIRGFLLEK 240
Query: 241 GMRGLSAPRIQGKFSLRASATGMIIMDGVEVPEENVLPGASSLGGPFGCLNNARYGIAWG 300
GMRGLSAPRIQGKFSLRASATGMIIMDGVEVPEENVLPGASSLGGPFGCLNNARYGIAWG
Sbjct: 241 GMRGLSAPRIQGKFSLRASATGMIIMDGVEVPEENVLPGASSLGGPFGCLNNARYGIAWG 300
Query: 301 VLGASEFCLHTARQYALDRMQFGVPLARNQLIQKKLADMLTEITLGLHACLQLGRLKDQD 360
VLGASEFCLHTARQYALDRMQFGVPLARNQLIQKKLADMLTEITLGLHACLQLGRLKDQD
Sbjct: 301 VLGASEFCLHTARQYALDRMQFGVPLARNQLIQKKLADMLTEITLGLHACLQLGRLKDQD 360
Query: 361 KAAPEMVSLLKRNNCGKALDIARQARDMLGGNGISDEYHVIRHAMNLEAVNTYE 414
KAAPEMVSLLKRNNCGKALDIARQARDMLGGNGISDEYHVIRHAMNLEAVNTYE
Sbjct: 361 KAAPEMVSLLKRNNCGKALDIARQARDMLGGNGISDEYHVIRHAMNLEAVNTYE 414
>gi|4557233 short-chain acyl-CoA dehydrogenase precursor [Homo
sapiens]
Length = 412
Score = 175 bits (443), Expect = 8e-44
Identities = 116/366 (31%), Positives = 182/366 (49%), Gaps = 10/366 (2%)
Query: 66 LIRDTFRTYCQERLMPRILLANRNEVFHREIISEMGELGVLGPTI-KGYGCAGVSSVAYG 124
++ T R + ++ L P ++ +F + +MG LG+L + + G AG+ +AY
Sbjct: 40 MLLQTCRDFAEKELFPIAAQVDKEHLFPAAQVKKMGGLGLLAMDVPEELGGAGLDYLAYA 99
Query: 125 LLARELERVDSGYRSAMSVQSSLVMHPIYAYGSEEQRQKYLPQLAKGELLGCFGLTEPNS 184
+ E+ R + MSV +SL + PI +GS+EQ+Q ++ G+ +GCF L+EP +
Sbjct: 100 IAMEEISRGCASTGVIMSVNNSLYLGPILKFGSKEQKQAWVTPFTSGDKIGCFALSEPGN 159
Query: 185 GSDPSSMETRAHYNSSNKSYTLNGTKTWITNSPMADLFVVWARCEDGC----IRGFLLEK 240
GSD + T A + S+ LNGTK WITN+ A VV+A + I FL+
Sbjct: 160 GSDAGAASTTAR--AEGDSWVLNGTKAWITNAWEASAAVVFASTDRALQNKGISAFLVPM 217
Query: 241 GMRGLSAPRIQGKFSLRASATGMIIMDGVEVPEENVLPGASSLGGPFGC--LNNARYGIA 298
GL+ + + K +R S+T +I + +P++++L G +G L+ R GIA
Sbjct: 218 PTPGLTLGKKEDKLGIRGSSTANLIFEDCRIPKDSIL-GEPGMGFKIAMQTLDMGRIGIA 276
Query: 299 WGVLGASEFCLHTARQYALDRMQFGVPLARNQLIQKKLADMLTEITLGLHACLQLGRLKD 358
LG ++ L A YA +RM FG PL + Q+IQ KLADM + + LKD
Sbjct: 277 SQALGIAQTALDCAVNYAENRMAFGAPLTKLQVIQFKLADMALALESARLLTWRAAMLKD 336
Query: 359 QDKAAPEMVSLLKRNNCGKALDIARQARDMLGGNGISDEYHVIRHAMNLEAVNTYEGTHD 418
K + ++ K A I+ QA +LGG G E RH + YEGT +
Sbjct: 337 NKKPFIKEAAMAKLAASEAATAISHQAIQILGGMGYVTEMPAERHYRDARITEIYEGTSE 396
Query: 419 IHALIL 424
I L++
Sbjct: 397 IQRLVI 402
>gi|226958412 isovaleryl Coenzyme A dehydrogenase isoform 1 [Homo
sapiens]
Length = 426
Score = 160 bits (404), Expect = 3e-39
Identities = 111/379 (29%), Positives = 184/379 (48%), Gaps = 14/379 (3%)
Query: 60 LTTDEILIRDTFRTYCQERLMPRILLANRNEVFH--REIISEMGELGVLGPTIK-GYGCA 116
L+ ++ +R T + QE L P+ +R+ F RE ++G LGVLG T YG +
Sbjct: 45 LSEEQRQLRQTMAKFLQEHLAPKAQEIDRSNEFKNLREFWKQLGNLGVLGITAPVQYGGS 104
Query: 117 GVSSVAYGLLARELERVDSGYRSAMSVQSSLVMHPIYAYGSEEQRQKYLPQLAKGELLGC 176
G+ + + L+ E+ R + S+L ++ + G+E Q++KYLP+L GE +G
Sbjct: 105 GLGYLEHVLVMEEISRASGAVGLSYGAHSNLCINQLVRNGNEAQKEKYLPKLISGEYIGA 164
Query: 177 FGLTEPNSGSDPSSMETRAHYNSSNKSYTLNGTKTWITNSPMADLFVVWARCEDGC---- 232
++EPN+GSD SM+ +A ++ Y LNG K WITN P AD+ +V+A+ +
Sbjct: 165 LAMSEPNAGSDVVSMKLKAEKKGNH--YILNGNKFWITNGPDADVLIVYAKTDLAAVPAS 222
Query: 233 --IRGFLLEKGMRGLSAPRIQGKFSLRASATGMIIMDGVEVPEENVLPGASSLG--GPFG 288
I F++EKGM G S + K +R S T +I + ++P N+L G + G
Sbjct: 223 RGITAFIVEKGMPGFSTSKKLDKLGMRGSNTCELIFEDCKIPAANIL-GHENKGVYVLMS 281
Query: 289 CLNNARYGIAWGVLGASEFCLHTARQYALDRMQFGVPLARNQLIQKKLADMLTEITLGLH 348
L+ R +A G LG + L Y R FG + QL+Q K+ADM T +
Sbjct: 282 GLDLERLVLAGGPLGLMQAVLDHTIPYLHVREAFGQKIGHFQLMQGKMADMYTRLMACRQ 341
Query: 349 ACLQLGRLKDQDKAAPEMVSLLKRNNCGKALDIARQARDMLGGNGISDEYHVIRHAMNLE 408
+ + D+ + + + + A +A GGNG +++ + R + +
Sbjct: 342 YVYNVAKACDEGHCTAKDCAGVILYSAECATQVALDGIQCFGGNGYINDFPMGRFLRDAK 401
Query: 409 AVNTYEGTHDIHALILGRA 427
GT ++ L++GRA
Sbjct: 402 LYEIGAGTSEVRRLVIGRA 420
>gi|4501859 acyl-Coenzyme A dehydrogenase, short/branched chain
precursor [Homo sapiens]
Length = 432
Score = 155 bits (393), Expect = 5e-38
Identities = 109/378 (28%), Positives = 190/378 (50%), Gaps = 11/378 (2%)
Query: 58 EQLTTDEILIRDTFRTYCQERLMPRILLANRNEVFHREIISEMGELGVLGPTIKG-YGCA 116
+ T +E++I+ + + + QE++ P + + N + +I + + G++G + YG
Sbjct: 55 QTFTDEEMMIKSSVKKFAQEQIAPLVSTMDENSKMEKSVIQGLFQQGLMGIEVDPEYGGT 114
Query: 117 GVSSVAYGLLARELERVDSGYRSAMSVQSSLVMHPIYAYGSEEQRQKYLPQLAKGELLGC 176
G S ++ L+ EL +VD+ +Q++L+ I +G+EEQ+ YLPQL E +G
Sbjct: 115 GASFLSTVLVIEELAKVDASVAVFCEIQNTLINTLIRKHGTEEQKATYLPQLTT-EKVGS 173
Query: 177 FGLTEPNSGSDPSSMETRAHYNSSNKSYTLNGTKTWITNSPMADLFVVWARCEDGC---- 232
F L+E +GSD +++TRA + Y LNG+K WI+++ A LF+V A +
Sbjct: 174 FCLSEAGAGSDSFALKTRA--DKEGDYYVLNGSKMWISSAEHAGLFLVMANVDPTIGYKG 231
Query: 233 IRGFLLEKGMRGLSAPRIQGKFSLRASATGMIIMDGVEVPEENVLPGASSLGGPF--GCL 290
I FL+++ GL + + K LRAS+T + + V+VPE N+L G G + G L
Sbjct: 232 ITSFLVDRDTPGLHIGKPENKLGLRASSTCPLTFENVKVPEANIL-GQIGHGYKYAIGSL 290
Query: 291 NNARYGIAWGVLGASEFCLHTARQYALDRMQFGVPLARNQLIQKKLADMLTEITLGLHAC 350
N R GIA +LG ++ C Y +R+QFG L Q +Q ++A + T++
Sbjct: 291 NEGRIGIAAQMLGLAQGCFDYTIPYIKERIQFGKRLFDFQGLQHQVAHVATQLEAARLLT 350
Query: 351 LQLGRLKDQDKAAPEMVSLLKRNNCGKALDIARQARDMLGGNGISDEYHVIRHAMNLEAV 410
RL + K + S+ K A + + +GG G + +Y V ++ + +
Sbjct: 351 YNAARLLEAGKPFIKEASMAKYYASEIAGQTTSKCIEWMGGVGYTKDYPVEKYFRDAKIG 410
Query: 411 NTYEGTHDIHALILGRAI 428
YEG +I + + I
Sbjct: 411 TIYEGASNIQLNTIAKHI 428
>gi|226958414 isovaleryl Coenzyme A dehydrogenase isoform 2 [Homo
sapiens]
Length = 396
Score = 148 bits (374), Expect = 8e-36
Identities = 102/348 (29%), Positives = 169/348 (48%), Gaps = 12/348 (3%)
Query: 89 NEVFHREIISEMGELGVLGPTIK-GYGCAGVSSVAYGLLARELERVDSGYRSAMSVQSSL 147
+E +E ++G LGVLG T YG +G+ + + L+ E+ R + S+L
Sbjct: 46 SEEQRQEFWKQLGNLGVLGITAPVQYGGSGLGYLEHVLVMEEISRASGAVGLSYGAHSNL 105
Query: 148 VMHPIYAYGSEEQRQKYLPQLAKGELLGCFGLTEPNSGSDPSSMETRAHYNSSNKSYTLN 207
++ + G+E Q++KYLP+L GE +G ++EPN+GSD SM+ +A ++ Y LN
Sbjct: 106 CINQLVRNGNEAQKEKYLPKLISGEYIGALAMSEPNAGSDVVSMKLKAEKKGNH--YILN 163
Query: 208 GTKTWITNSPMADLFVVWARCEDGC------IRGFLLEKGMRGLSAPRIQGKFSLRASAT 261
G K WITN P AD+ +V+A+ + I F++EKGM G S + K +R S T
Sbjct: 164 GNKFWITNGPDADVLIVYAKTDLAAVPASRGITAFIVEKGMPGFSTSKKLDKLGMRGSNT 223
Query: 262 GMIIMDGVEVPEENVLPGASSLG--GPFGCLNNARYGIAWGVLGASEFCLHTARQYALDR 319
+I + ++P N+L G + G L+ R +A G LG + L Y R
Sbjct: 224 CELIFEDCKIPAANIL-GHENKGVYVLMSGLDLERLVLAGGPLGLMQAVLDHTIPYLHVR 282
Query: 320 MQFGVPLARNQLIQKKLADMLTEITLGLHACLQLGRLKDQDKAAPEMVSLLKRNNCGKAL 379
FG + QL+Q K+ADM T + + + D+ + + + + A
Sbjct: 283 EAFGQKIGHFQLMQGKMADMYTRLMACRQYVYNVAKACDEGHCTAKDCAGVILYSAECAT 342
Query: 380 DIARQARDMLGGNGISDEYHVIRHAMNLEAVNTYEGTHDIHALILGRA 427
+A GGNG +++ + R + + GT ++ L++GRA
Sbjct: 343 QVALDGIQCFGGNGYINDFPMGRFLRDAKLYEIGAGTSEVRRLVIGRA 390
>gi|4557235 acyl-Coenzyme A dehydrogenase, very long chain isoform 1
precursor [Homo sapiens]
Length = 655
Score = 148 bits (374), Expect = 8e-36
Identities = 105/339 (30%), Positives = 165/339 (48%), Gaps = 13/339 (3%)
Query: 97 ISEMGELGVLGPTIKGYGCAGVSSVAYGLLARELERVDSGYRSAMSVQSSLVMHPIYAYG 156
+ E+G G+ P+ G G+ + Y L + D G + S+ I +G
Sbjct: 136 LKELGAFGLQVPS--ELGGVGLCNTQYARLVEIVGMHDLGVGITLGAHQSIGFKGILLFG 193
Query: 157 SEEQRQKYLPQLAKGELLGCFGLTEPNSGSDPSSMETRAHYNSSNKSYTLNGTKTWITNS 216
++ Q++KYLP+LA GE + F LTEP+SGSD +S+ T A + K YTLNG+K WI+N
Sbjct: 194 TKAQKEKYLPKLASGETVAAFCLTEPSSGSDAASIRTSAVPSPCGKYYTLNGSKLWISNG 253
Query: 217 PMADLFVVWARC-----EDGCIR----GFLLEKGMRGLSAPRIQGKFSLRASATGMIIMD 267
+AD+F V+A+ G ++ F++E+G G++ + K ++AS T + D
Sbjct: 254 GLADIFTVFAKTPVTDPATGAVKEKITAFVVERGFGGITHGPPEKKMGIKASNTAEVFFD 313
Query: 268 GVEVPEENVL-PGASSLGGPFGCLNNARYGIAWGVLGASEFCLHTARQYALDRMQFGVPL 326
GV VP ENVL S LNN R+G+A + G + A +A +R QFG +
Sbjct: 314 GVRVPSENVLGEVGSGFKVAMHILNNGRFGMAAALAGTMRGIIAKAVDHATNRTQFGEKI 373
Query: 327 ARNQLIQKKLADMLTEITLGLHACLQLGRLKDQDKAAPEM-VSLLKRNNCGKALDIARQA 385
LIQ+KLA M+ + + DQ ++ ++ K A + +
Sbjct: 374 HNFGLIQEKLARMVMLQYVTESMAYMVSANMDQGATDFQIEAAISKIFGSEAAWKVTDEC 433
Query: 386 RDMLGGNGISDEYHVIRHAMNLEAVNTYEGTHDIHALIL 424
++GG G E V R +L +EGT+DI L +
Sbjct: 434 IQIMGGMGFMKEPGVERVLRDLRIFRIFEGTNDILRLFV 472
>gi|76496475 acyl-Coenzyme A dehydrogenase, very long chain isoform
2 precursor [Homo sapiens]
Length = 633
Score = 148 bits (374), Expect = 8e-36
Identities = 105/339 (30%), Positives = 165/339 (48%), Gaps = 13/339 (3%)
Query: 97 ISEMGELGVLGPTIKGYGCAGVSSVAYGLLARELERVDSGYRSAMSVQSSLVMHPIYAYG 156
+ E+G G+ P+ G G+ + Y L + D G + S+ I +G
Sbjct: 114 LKELGAFGLQVPS--ELGGVGLCNTQYARLVEIVGMHDLGVGITLGAHQSIGFKGILLFG 171
Query: 157 SEEQRQKYLPQLAKGELLGCFGLTEPNSGSDPSSMETRAHYNSSNKSYTLNGTKTWITNS 216
++ Q++KYLP+LA GE + F LTEP+SGSD +S+ T A + K YTLNG+K WI+N
Sbjct: 172 TKAQKEKYLPKLASGETVAAFCLTEPSSGSDAASIRTSAVPSPCGKYYTLNGSKLWISNG 231
Query: 217 PMADLFVVWARC-----EDGCIR----GFLLEKGMRGLSAPRIQGKFSLRASATGMIIMD 267
+AD+F V+A+ G ++ F++E+G G++ + K ++AS T + D
Sbjct: 232 GLADIFTVFAKTPVTDPATGAVKEKITAFVVERGFGGITHGPPEKKMGIKASNTAEVFFD 291
Query: 268 GVEVPEENVL-PGASSLGGPFGCLNNARYGIAWGVLGASEFCLHTARQYALDRMQFGVPL 326
GV VP ENVL S LNN R+G+A + G + A +A +R QFG +
Sbjct: 292 GVRVPSENVLGEVGSGFKVAMHILNNGRFGMAAALAGTMRGIIAKAVDHATNRTQFGEKI 351
Query: 327 ARNQLIQKKLADMLTEITLGLHACLQLGRLKDQDKAAPEM-VSLLKRNNCGKALDIARQA 385
LIQ+KLA M+ + + DQ ++ ++ K A + +
Sbjct: 352 HNFGLIQEKLARMVMLQYVTESMAYMVSANMDQGATDFQIEAAISKIFGSEAAWKVTDEC 411
Query: 386 RDMLGGNGISDEYHVIRHAMNLEAVNTYEGTHDIHALIL 424
++GG G E V R +L +EGT+DI L +
Sbjct: 412 IQIMGGMGFMKEPGVERVLRDLRIFRIFEGTNDILRLFV 450
>gi|21361497 acyl-Coenzyme A dehydrogenase family, member 9 [Homo
sapiens]
Length = 621
Score = 142 bits (357), Expect = 8e-34
Identities = 104/354 (29%), Positives = 177/354 (50%), Gaps = 23/354 (6%)
Query: 95 EIISEMGELGVLGPTI-KGYGCAGVSSVAYGLLARELERVDSGYRSAMSVQSSLVMHPIY 153
E + ++ LG+ G + + YG G S+ Y L E+ +D ++ ++ + I
Sbjct: 96 ETLEKLKSLGLFGLQVPEEYGGLGFSNTMYSRLG-EIISMDGSITVTLAAHQAIGLKGII 154
Query: 154 AYGSEEQRQKYLPQLAKGELLGCFGLTEPNSGSDPSSMETRAHYNSSNKSYTLNGTKTWI 213
G+EEQ+ KYLP+LA GE + F LTEP SGSD +S+ +RA + K Y LNG+K WI
Sbjct: 155 LAGTEEQKAKYLPKLASGEHIAAFCLTEPASGSDAASIRSRATLSEDKKHYILNGSKVWI 214
Query: 214 TNSPMADLFVVWARCE----DGCIR----GFLLEKGMRGLSAPRIQGKFSLRASATGMII 265
TN +A++F V+A+ E DG ++ F++E+ G++ + + K +R S T +
Sbjct: 215 TNGGLANIFTVFAKTEVVDSDGSVKDKITAFIVERDFGGVTNGKPEDKLGIRGSNTCEVH 274
Query: 266 MDGVEVPEENVLPGASSLGGPF----GCLNNARYGIAWGVLGASEFCLHTARQYALDRMQ 321
+ ++P EN+L +G F LN+ R+ + V G + + +YA R Q
Sbjct: 275 FENTKIPVENIL---GEVGDGFKVAMNILNSGRFSMGSVVAGLLKRLIEMTAEYACTRKQ 331
Query: 322 FGVPLARNQLIQKKLADMLTEITLGLHACLQLGRLKDQDKAAPEM---VSLLKRNNCGKA 378
F L+ LIQ+K A M + + + DQ P+ +++K + A
Sbjct: 332 FNKRLSEFGLIQEKFALMAQKAYVMESMTYLTAGMLDQ-PGFPDCSIEAAMVKVFSSEAA 390
Query: 379 LDIARQARDMLGGNGISDEYHVIRHAMNLEAVNTYEGTHDIHALILGRAITGIQ 432
+A +LGG G + +Y R + + +EGT++I + + A+TG+Q
Sbjct: 391 WQCVSEALQILGGLGYTRDYPYERILRDTRILLIFEGTNEILRMYI--ALTGLQ 442
>gi|187960098 medium-chain acyl-CoA dehydrogenase isoform b
precursor [Homo sapiens]
Length = 425
Score = 140 bits (353), Expect = 2e-33
Identities = 110/399 (27%), Positives = 190/399 (47%), Gaps = 15/399 (3%)
Query: 37 QSQLAKSSRPEFDWQDPLVLEEQLTTDEILIRDTFRTYCQERLMPRILLANRNEVFHREI 96
+SQ K++R + L + T + + T R + +E ++P ++ + +
Sbjct: 25 RSQHTKANRQR---EPGLGFSFEFTEQQKEFQATARKFAREEIIPVAAEYDKTGEYPVPL 81
Query: 97 ISEMGELGVLGPTI-KGYGCAGVSSVAYGLLARELERVDSGYRSAMSVQSSLVMHPIYAY 155
I ELG++ I + G G+ + L++ EL +G ++A+ +SL PI
Sbjct: 82 IRRAWELGLMNTHIPENCGGLGLGTFDACLISEELAYGCTGVQTAIE-GNSLGQMPIIIA 140
Query: 156 GSEEQRQKYLPQLAKGELLGCFGLTEPNSGSDPSSMETRAHYNSSNKSYTLNGTKTWITN 215
G+++Q++KYL ++ + L+ + +TEP +GSD + ++T+A Y +NG K WITN
Sbjct: 141 GNDQQKKKYLGRMTEEPLMCAYCVTEPGAGSDVAGIKTKA--EKKGDEYIINGQKMWITN 198
Query: 216 SPMADLFVVWARCE-------DGCIRGFLLEKGMRGLSAPRIQGKFSLRASATGMIIMDG 268
A+ + + AR + + GF++E G+ R + R S T I+ +
Sbjct: 199 GGKANWYFLLARSDPDPKAPANKAFTGFIVEADTPGIQIGRKELNMGQRCSDTRGIVFED 258
Query: 269 VEVPEENVLPG-ASSLGGPFGCLNNARYGIAWGVLGASEFCLHTARQYALDRMQFGVPLA 327
V+VP+ENVL G + G + R +A G +G ++ L A +YAL+R FG L
Sbjct: 259 VKVPKENVLIGDGAGFKVAMGAFDKTRPVVAAGAVGLAQRALDEATKYALERKTFGKLLV 318
Query: 328 RNQLIQKKLADMLTEITLGLHACLQLGRLKDQDKAAPEMVSLLKRNNCGKALDIARQARD 387
+Q I LA+M ++ L + + D + S+ K A +A A
Sbjct: 319 EHQAISFMLAEMAMKVELARMSYQRAAWEVDSGRRNTYYASIAKAFAGDIANQLATDAVQ 378
Query: 388 MLGGNGISDEYHVIRHAMNLEAVNTYEGTHDIHALILGR 426
+LGGNG + EY V + + + YEGT I LI+ R
Sbjct: 379 ILGGNGFNTEYPVEKLMRDAKIYQIYEGTSQIQRLIVAR 417
>gi|4557231 medium-chain acyl-CoA dehydrogenase isoform a precursor
[Homo sapiens]
Length = 421
Score = 140 bits (353), Expect = 2e-33
Identities = 110/399 (27%), Positives = 190/399 (47%), Gaps = 15/399 (3%)
Query: 37 QSQLAKSSRPEFDWQDPLVLEEQLTTDEILIRDTFRTYCQERLMPRILLANRNEVFHREI 96
+SQ K++R + L + T + + T R + +E ++P ++ + +
Sbjct: 21 RSQHTKANRQR---EPGLGFSFEFTEQQKEFQATARKFAREEIIPVAAEYDKTGEYPVPL 77
Query: 97 ISEMGELGVLGPTI-KGYGCAGVSSVAYGLLARELERVDSGYRSAMSVQSSLVMHPIYAY 155
I ELG++ I + G G+ + L++ EL +G ++A+ +SL PI
Sbjct: 78 IRRAWELGLMNTHIPENCGGLGLGTFDACLISEELAYGCTGVQTAIE-GNSLGQMPIIIA 136
Query: 156 GSEEQRQKYLPQLAKGELLGCFGLTEPNSGSDPSSMETRAHYNSSNKSYTLNGTKTWITN 215
G+++Q++KYL ++ + L+ + +TEP +GSD + ++T+A Y +NG K WITN
Sbjct: 137 GNDQQKKKYLGRMTEEPLMCAYCVTEPGAGSDVAGIKTKA--EKKGDEYIINGQKMWITN 194
Query: 216 SPMADLFVVWARCE-------DGCIRGFLLEKGMRGLSAPRIQGKFSLRASATGMIIMDG 268
A+ + + AR + + GF++E G+ R + R S T I+ +
Sbjct: 195 GGKANWYFLLARSDPDPKAPANKAFTGFIVEADTPGIQIGRKELNMGQRCSDTRGIVFED 254
Query: 269 VEVPEENVLPG-ASSLGGPFGCLNNARYGIAWGVLGASEFCLHTARQYALDRMQFGVPLA 327
V+VP+ENVL G + G + R +A G +G ++ L A +YAL+R FG L
Sbjct: 255 VKVPKENVLIGDGAGFKVAMGAFDKTRPVVAAGAVGLAQRALDEATKYALERKTFGKLLV 314
Query: 328 RNQLIQKKLADMLTEITLGLHACLQLGRLKDQDKAAPEMVSLLKRNNCGKALDIARQARD 387
+Q I LA+M ++ L + + D + S+ K A +A A
Sbjct: 315 EHQAISFMLAEMAMKVELARMSYQRAAWEVDSGRRNTYYASIAKAFAGDIANQLATDAVQ 374
Query: 388 MLGGNGISDEYHVIRHAMNLEAVNTYEGTHDIHALILGR 426
+LGGNG + EY V + + + YEGT I LI+ R
Sbjct: 375 ILGGNGFNTEYPVEKLMRDAKIYQIYEGTSQIQRLIVAR 413
>gi|4501857 long-chain acyl-CoA dehydrogenase precursor [Homo
sapiens]
Length = 430
Score = 123 bits (308), Expect = 4e-28
Identities = 104/375 (27%), Positives = 169/375 (45%), Gaps = 19/375 (5%)
Query: 66 LIRDTFRTYCQERLMPRILLANRNEVFHREIISEMGELGVLGPTIKGYGCAGVSSVAYGL 125
+ R + R + QE ++P + RE+ + G+ G+LG I + G+ Y
Sbjct: 59 IFRKSVRKFFQEEVIPHHSEWEKAGEVSREVWEKAGKQGLLGVNIAEH-LGGIGGDLYSA 117
Query: 126 -LARELERVDSGYRSAMSVQSSLVMHPIYAYGSEEQRQKYLPQLAKGELLGCFGLTEPNS 184
+ E + + S+ S +VM I +GSEEQ + ++PQ+ G+ +G +TEP +
Sbjct: 118 AIVWEEQAYSNCSGPGFSIHSGIVMSYITNHGSEEQIKHFIPQMTAGKCIGAIAMTEPGA 177
Query: 185 GSDPSSMETRAHYNSSNKSYTLNGTKTWITNSPMADLFVVWARCEDGC------IRGFLL 238
GSD ++T A + S+ + LNG+K +I+N ++D+ +V A I FL+
Sbjct: 178 GSDLQGIKTNAKKDGSD--WILNGSKVFISNGSLSDVVIVVAVTNHEAPSPAHGISLFLV 235
Query: 239 EKGMRGLSAPRIQGKFSLRASATGMIIMDGVEVPEENVLPGASSLGGPFGC--LNNARYG 296
E GM+G R K L+A T + + + +P +L G + G + L R
Sbjct: 236 ENGMKGFIKGRKLHKMGLKAQDTAELFFEDIRLPASALL-GEENKGFYYIMKELPQERLL 294
Query: 297 IAWGVLGASEFCLHTARQYALDRMQFGVPLARNQLIQKKLADMLTEITLG---LHACLQL 353
IA + ASEF R Y R FG +A Q +Q KLA++ T I + + CLQL
Sbjct: 295 IADVAISASEFMFEETRNYVKQRKAFGKTVAHLQTVQHKLAELKTHICVTRAFVDNCLQL 354
Query: 354 GRLKDQDKAAPEMVSLLKRNNCGKALDIARQARDMLGGNGISDEYHVIRHAMNLEAVNTY 413
K D A M +A + GG G EY + + ++ Y
Sbjct: 355 HEAKRLDSATACMAKYWASE---LQNSVAYDCVQLHGGWGYMWEYPIAKAYVDARVQPIY 411
Query: 414 EGTHDIHALILGRAI 428
GT++I ++ R I
Sbjct: 412 GGTNEIMKELIAREI 426
>gi|7656849 acyl-Coenzyme A dehydrogenase family, member 8 [Homo
sapiens]
Length = 415
Score = 121 bits (303), Expect = 1e-27
Identities = 100/362 (27%), Positives = 171/362 (47%), Gaps = 11/362 (3%)
Query: 74 YCQERLMPRILLANRNEVFHREIISEMGELGVLGPTIK-GYGCAGVSSVAYGLLARELER 132
+ + P + ++ E+F +++ + +LG G I+ G +G+S + ++ L
Sbjct: 55 FAAREMAPNMAEWDQKELFPVDVMRKAAQLGFGGVYIQTDVGGSGLSRLDTSVIFEALAT 114
Query: 133 VDSGYRSAMSVQSSLVMHPIYAYGSEEQRQKYLPQLAKGELLGCFGLTEPNSGSDPSSME 192
+ + +S+ + + I ++G+EEQR K+ P L E + LTEP SGSD +S+
Sbjct: 115 GCTSTTAYISIHN-MCAWMIDSFGNEEQRHKFCPPLCTMEKFASYCLTEPGSGSDAASLL 173
Query: 193 TRAHYNSSNKSYTLNGTKTWITNSPMADLFVVWARCEDGCIRG---FLLEKGMRGLSAPR 249
T A Y LNG+K +I+ + +D++VV R +G ++EKG GLS +
Sbjct: 174 TSA--KKQGDHYILNGSKAFISGAGESDIYVVMCRTGGPGPKGISCIVVEKGTPGLSFGK 231
Query: 250 IQGKFSLRASATGMIIMDGVEVPEENVLPGASSLGGPFGC--LNNARYGIAWGVLGASEF 307
+ K + T +I + VP N + G+ G LN R IA LGA+
Sbjct: 232 KEKKVGWNSQPTRAVIFEDCAVPVANRI-GSEGQGFLIAVRGLNGGRINIASCSLGAAHA 290
Query: 308 CLHTARQYALDRMQFGVPLARNQLIQKKLADMLTEITLG-LHACLQLGRLKDQDKAAPEM 366
+ R + R QFG PLA NQ +Q LADM T + L L+++ K A +
Sbjct: 291 SVILTRDHLNVRKQFGEPLASNQYLQFTLADMATRLVAARLMVRNAAVALQEERKDAVAL 350
Query: 367 VSLLKRNNCGKALDIARQARDMLGGNGISDEYHVIRHAMNLEAVNTYEGTHDIHALILGR 426
S+ K + I QA M GG G +Y V ++ + EG++++ +++ R
Sbjct: 351 CSMAKLFATDECFAICNQALQMHGGYGYLKDYAVQQYVRDSRVHQILEGSNEVMRILISR 410
Query: 427 AI 428
++
Sbjct: 411 SL 412
>gi|211971008 acyl-Coenzyme A dehydrogenase family, member 10 isoform
a [Homo sapiens]
Length = 1090
Score = 71.2 bits (173), Expect = 2e-12
Identities = 72/288 (25%), Positives = 118/288 (40%), Gaps = 21/288 (7%)
Query: 149 MHPIYAYGSEEQRQKYLPQLAKGELLGCFGLTEPN-SGSDPSSMETRAHYNSSNKSYTLN 207
M + YG+E Q+ ++L L +G+ CF +TEP + SD +++E A + Y +N
Sbjct: 795 MELLVRYGTEAQKARWLIPLLEGKARSCFAMTEPQVASSDATNIE--ASIREEDSFYVIN 852
Query: 208 GTKTWITN--SPMADLFVVWARCEDGCIRG-----FLLEKGMRGLSAPRIQGKFSLR--A 258
G K WIT P L V + + R L+ G+ R + L
Sbjct: 853 GHKWWITGILDPRCQLCVFMGKTDPHAPRHRQQSVLLVPMDTPGIKIIRPLTVYGLEDAP 912
Query: 259 SATGMIIMDGVEVPEENVLPGASSLGGPF----GCLNNARYGIAWGVLGASEFCLHTARQ 314
G + + V VP+EN++ G G F G L R ++G SE L +
Sbjct: 913 GGHGEVRFEHVRVPKENMVLGP---GRGFEIAQGRLGPGRIHHCMRLIGFSERALALMKA 969
Query: 315 YALDRMQFGVPLARNQLIQKKLADMLTEITLGLHACLQLGRLKD--QDKAAPEMVSLLKR 372
R+ FG PL + +A EI L+ L D +KAA ++++K
Sbjct: 970 RVKSRLAFGKPLVEQGTVLADIAQSRVEIEQARLLVLRAAHLMDLAGNKAAALDIAMIKM 1029
Query: 373 NNCGKALDIARQARDMLGGNGISDEYHVIRHAMNLEAVNTYEGTHDIH 420
A + +A G G+S +Y + + A+ +G ++H
Sbjct: 1030 VAPSMASRVIDRAIQAFGAAGLSSDYPLAQFFTWARALRFADGPDEVH 1077
>gi|48976061 acyl-Coenzyme A dehydrogenase family, member 10 isoform b
[Homo sapiens]
Length = 1059
Score = 71.2 bits (173), Expect = 2e-12
Identities = 72/288 (25%), Positives = 118/288 (40%), Gaps = 21/288 (7%)
Query: 149 MHPIYAYGSEEQRQKYLPQLAKGELLGCFGLTEPN-SGSDPSSMETRAHYNSSNKSYTLN 207
M + YG+E Q+ ++L L +G+ CF +TEP + SD +++E A + Y +N
Sbjct: 764 MELLVRYGTEAQKARWLIPLLEGKARSCFAMTEPQVASSDATNIE--ASIREEDSFYVIN 821
Query: 208 GTKTWITN--SPMADLFVVWARCEDGCIRG-----FLLEKGMRGLSAPRIQGKFSLR--A 258
G K WIT P L V + + R L+ G+ R + L
Sbjct: 822 GHKWWITGILDPRCQLCVFMGKTDPHAPRHRQQSVLLVPMDTPGIKIIRPLTVYGLEDAP 881
Query: 259 SATGMIIMDGVEVPEENVLPGASSLGGPF----GCLNNARYGIAWGVLGASEFCLHTARQ 314
G + + V VP+EN++ G G F G L R ++G SE L +
Sbjct: 882 GGHGEVRFEHVRVPKENMVLGP---GRGFEIAQGRLGPGRIHHCMRLIGFSERALALMKA 938
Query: 315 YALDRMQFGVPLARNQLIQKKLADMLTEITLGLHACLQLGRLKD--QDKAAPEMVSLLKR 372
R+ FG PL + +A EI L+ L D +KAA ++++K
Sbjct: 939 RVKSRLAFGKPLVEQGTVLADIAQSRVEIEQARLLVLRAAHLMDLAGNKAAALDIAMIKM 998
Query: 373 NNCGKALDIARQARDMLGGNGISDEYHVIRHAMNLEAVNTYEGTHDIH 420
A + +A G G+S +Y + + A+ +G ++H
Sbjct: 999 VAPSMASRVIDRAIQAFGAAGLSSDYPLAQFFTWARALRFADGPDEVH 1046
>gi|157502163 acyl-Coenzyme A oxidase-like 2 [Homo sapiens]
Length = 547
Score = 60.1 bits (144), Expect = 4e-09
Identities = 72/321 (22%), Positives = 128/321 (39%), Gaps = 48/321 (14%)
Query: 156 GSEEQRQKYLPQLAKGELLGCFGLTEPNSGSDPSSMETRAHYNSSNKSYTL-----NGTK 210
GS E K+ L + + G F +TE GS+ ++T A ++ S + + + N K
Sbjct: 69 GSPEHVTKWFQPLQEQKYTGMFAMTERGHGSNARGIQTEATFDLSAQEFVIDTPCENAEK 128
Query: 211 TWITNSPMADLFVVWAR-CEDGCIRG---FLL----EKG--MRGLSAPRIQGKFSLRASA 260
+I N+ + V+A+ DG +G F++ E G G++A + K L
Sbjct: 129 MYIGNAMYGNYAAVFAQLIIDGRSQGPHCFIVPVRDENGSLYPGVTAIDMMYKEGLHGVD 188
Query: 261 TGMIIMDGVEVPEENVLPGASSL-----------------GGPFGCLNNARYGIAWGVLG 303
G++I D V +P EN+L S+ L +R +A+ +G
Sbjct: 189 NGILIFDKVRIPRENLLDKFGSVAPDGQYHSPIRNKSARFNAMLAALTPSRLAVAFQAMG 248
Query: 304 ASEFCLHTARQYALDRMQFG------VPLARNQLIQKKLADMLTEITLGLHACLQLGRLK 357
A + L A +Y+ R QFG V + +Q +L L G L
Sbjct: 249 AMKLGLTIAIRYSHSRRQFGPKTKEEVKIIEHQTQTLRLMPHLATALALTFVSRYAGALL 308
Query: 358 DQD----------KAAPEMVSLLKRNNCGKALDIARQARDMLGGNGISDEYHVIRHAMNL 407
D+D ++ +V+ LK + + + + R+ GG G E + +
Sbjct: 309 DEDVFQGKELVNSRSLQALVAGLKAYSTWENIRCLQDCRECTGGMGYMMENRISGLKCDT 368
Query: 408 EAVNTYEGTHDIHALILGRAI 428
+ T+EG + ++GR +
Sbjct: 369 DVFATFEGDDVVMLQVVGREL 389
>gi|38505218 putative acyl-CoA dehydrogenase [Homo sapiens]
Length = 780
Score = 58.9 bits (141), Expect = 9e-09
Identities = 79/330 (23%), Positives = 133/330 (40%), Gaps = 36/330 (10%)
Query: 116 AGVSSVAYGLLARELERV----DSGYRSAMSVQSSLVMHPIYAYGSEEQRQKYLPQLAKG 171
+G+S V Y L+A E + D A + V+H YGSEEQ++++L L +G
Sbjct: 442 SGLSHVDYALIAEETGKCFFAPDVFNCQAPDTGNMEVLH---LYGSEEQKKQWLEPLLQG 498
Query: 172 ELLGCFGLTEPN-SGSDPSSMETRAHYNSSNKSYTLNGTKTWIT--NSPMADLFVVWARC 228
+ CF +TEP+ + SD +++E SY +NG K W + +P + +V R
Sbjct: 499 NITSCFCMTEPDVASSDATNIE--CSIQRDEDSYVINGKKWWSSGAGNPKCKIAIVLGRT 556
Query: 229 EDGCIRG------FLLEKGMRGLSAPRIQGKFSLRASATG---MIIMDGVEVPEENVLPG 279
++ + L+ G+ R F + G I + V VP N++ G
Sbjct: 557 QNTSLSRHKQHSMILVPMNTPGVKIIRPLSVFGYTDNFHGGHFEIHFNQVRVPATNLILG 616
Query: 280 ASSLGGPF----GCLNNARYGIAWGVLGASEFCLHTARQYALDRMQFGVPLARNQLIQKK 335
G F G L R +G +E L + A R+ F L ++++
Sbjct: 617 E---GRGFEISQGRLGPGRIHHCMRTVGLAERALQIMCERATQRIAFKKKLYAHEVVAHW 673
Query: 336 LADMLTEI----TLGLHACLQLGRLKDQD-KAAPEMVSLLKRNNCGKALDIARQARDMLG 390
+A+ I L L A + L K M+ + K +D A Q + G
Sbjct: 674 IAESRIAIEKIRLLTLKAAHSMDTLGSAGAKKEIAMIKVAAPRAVSKIVDWAIQ---VCG 730
Query: 391 GNGISDEYHVIRHAMNLEAVNTYEGTHDIH 420
G G+S +Y + + +G ++H
Sbjct: 731 GAGVSQDYPLANMYAITRVLRLADGPDEVH 760
>gi|218563754 acyl-Coenzyme A oxidase-like 3 [Homo sapiens]
Length = 517
Score = 51.6 bits (122), Expect = 1e-06
Identities = 51/200 (25%), Positives = 86/200 (43%), Gaps = 32/200 (16%)
Query: 156 GSEEQRQKYLPQLAKGELLGCFGLTEPNSGSDPSSMETRAHYNSSNKSYTL-----NGTK 210
GS E K+ L + + G F +TE GS+ ++T A ++ S + + + N K
Sbjct: 69 GSPEHVTKWFQPLQEQKYTGMFAMTERGHGSNARGIQTEATFDLSAQEFVIDTPCENAEK 128
Query: 211 TWITNSPMADLFVVWAR-CEDGCIRG---FLL----EKG--MRGLSAPRIQGKFSLRASA 260
+I N+ + V+A+ DG +G F++ E G G++A + K L
Sbjct: 129 MYIGNAMYGNYAAVFAQLIIDGRSQGPHCFIVPVRDENGSLYPGVTAIDMMYKEGLHGVD 188
Query: 261 TGMIIMDGVEVPEENVLPGASSL-----------------GGPFGCLNNARYGIAWGVLG 303
G++I D V +P EN+L S+ L +R +A+ +G
Sbjct: 189 NGILIFDKVRIPRENLLDKFGSVAPDGQYHSPIRNKSARFNAMLAALTPSRLAVAFQAMG 248
Query: 304 ASEFCLHTARQYALDRMQFG 323
A + L A +Y+ R QFG
Sbjct: 249 AMKLGLTIAIRYSHSRRQFG 268
>gi|218563752 acyl-Coenzyme A oxidase-like 1 [Homo sapiens]
Length = 580
Score = 51.6 bits (122), Expect = 1e-06
Identities = 51/200 (25%), Positives = 86/200 (43%), Gaps = 32/200 (16%)
Query: 156 GSEEQRQKYLPQLAKGELLGCFGLTEPNSGSDPSSMETRAHYNSSNKSYTL-----NGTK 210
GS E K+ L + + G F +TE GS+ ++T A ++ S + + + N K
Sbjct: 69 GSPEHVTKWFQPLQEQKYTGMFAMTERGHGSNARGIQTEATFDLSAQEFVIDTPCENAEK 128
Query: 211 TWITNSPMADLFVVWAR-CEDGCIRG---FLL----EKG--MRGLSAPRIQGKFSLRASA 260
+I N+ + V+A+ DG +G F++ E G G++A + K L
Sbjct: 129 MYIGNAMYGNYAAVFAQLIIDGRSQGPHCFIVPVRDENGSLYPGVTAIDMMYKEGLHGVD 188
Query: 261 TGMIIMDGVEVPEENVLPGASSL-----------------GGPFGCLNNARYGIAWGVLG 303
G++I D V +P EN+L S+ L +R +A+ +G
Sbjct: 189 NGILIFDKVRIPRENLLDKFGSVAPDGQYHSPIRNKSARFNAMLAALTPSRLAVAFQAMG 248
Query: 304 ASEFCLHTARQYALDRMQFG 323
A + L A +Y+ R QFG
Sbjct: 249 AMKLGLTIAIRYSHSRRQFG 268
>gi|156104866 acyl-Coenzyme A oxidase 3 isoform b [Homo sapiens]
Length = 624
Score = 47.8 bits (112), Expect = 2e-05
Identities = 50/225 (22%), Positives = 92/225 (40%), Gaps = 36/225 (16%)
Query: 134 DSGYRSAMSVQSSLVMHPIYAYGSEEQRQKYLPQLAKGELLGCFGLTEPNSGSDPSSMET 193
DS + + S + +Y+ GSE + Y+ ++ + E+ GCF LTE + GS+ ++ T
Sbjct: 114 DSSLAAKYLLHSLVFGSAVYSSGSE-RHLTYIQKIFRMEIFGCFALTELSHGSNTKAIRT 172
Query: 194 RAHYNSSNKSYTLN-----GTKTWITN-SPMADLFVVWARC---EDGC--IRGFLLE--- 239
AHY+ + + + ++ K W+ N A VV+A+ D C + F+++
Sbjct: 173 TAHYDPATEEFIIHSPDFEAAKFWVGNMGKTATHAVVFAKLCVPGDQCHGLHPFIVQIRD 232
Query: 240 ----KGMRGLSAPRIQGKFSLRASATGMIIMDGVEVPEENVLPGASSL------------ 283
M G+ I K G + V VP +++L +
Sbjct: 233 PKTLLPMPGVMVGDIGKKLGQNGLDNGFAMFHKVRVPRQSLLNRMGDVTPEGTYVSPFKD 292
Query: 284 -----GGPFGCLNNARYGIAWGVLGASEFCLHTARQYALDRMQFG 323
G G L++ R I + + + A +++ R QFG
Sbjct: 293 VRQRFGASLGSLSSGRVSIVSLAILNLKLAVAIALRFSATRRQFG 337
>gi|156104864 acyl-Coenzyme A oxidase 3 isoform a [Homo sapiens]
Length = 700
Score = 47.8 bits (112), Expect = 2e-05
Identities = 50/225 (22%), Positives = 92/225 (40%), Gaps = 36/225 (16%)
Query: 134 DSGYRSAMSVQSSLVMHPIYAYGSEEQRQKYLPQLAKGELLGCFGLTEPNSGSDPSSMET 193
DS + + S + +Y+ GSE + Y+ ++ + E+ GCF LTE + GS+ ++ T
Sbjct: 114 DSSLAAKYLLHSLVFGSAVYSSGSE-RHLTYIQKIFRMEIFGCFALTELSHGSNTKAIRT 172
Query: 194 RAHYNSSNKSYTLN-----GTKTWITN-SPMADLFVVWARC---EDGC--IRGFLLE--- 239
AHY+ + + + ++ K W+ N A VV+A+ D C + F+++
Sbjct: 173 TAHYDPATEEFIIHSPDFEAAKFWVGNMGKTATHAVVFAKLCVPGDQCHGLHPFIVQIRD 232
Query: 240 ----KGMRGLSAPRIQGKFSLRASATGMIIMDGVEVPEENVLPGASSL------------ 283
M G+ I K G + V VP +++L +
Sbjct: 233 PKTLLPMPGVMVGDIGKKLGQNGLDNGFAMFHKVRVPRQSLLNRMGDVTPEGTYVSPFKD 292
Query: 284 -----GGPFGCLNNARYGIAWGVLGASEFCLHTARQYALDRMQFG 323
G G L++ R I + + + A +++ R QFG
Sbjct: 293 VRQRFGASLGSLSSGRVSIVSLAILNLKLAVAIALRFSATRRQFG 337
>gi|211971012 acyl-Coenzyme A dehydrogenase family, member 10
isoform c [Homo sapiens]
Length = 890
Score = 46.2 bits (108), Expect = 6e-05
Identities = 24/67 (35%), Positives = 38/67 (56%), Gaps = 3/67 (4%)
Query: 149 MHPIYAYGSEEQRQKYLPQLAKGELLGCFGLTEPN-SGSDPSSMETRAHYNSSNKSYTLN 207
M + YG+E Q+ ++L L +G+ CF +TEP + SD +++E A + Y +N
Sbjct: 764 MELLVRYGTEAQKARWLIPLLEGKARSCFAMTEPQVASSDATNIE--ASIREEDSFYVIN 821
Query: 208 GTKTWIT 214
G K WIT
Sbjct: 822 GHKWWIT 828
>gi|4501869 acyl-Coenzyme A oxidase 2 [Homo sapiens]
Length = 681
Score = 38.9 bits (89), Expect = 0.009
Identities = 45/181 (24%), Positives = 74/181 (40%), Gaps = 29/181 (16%)
Query: 125 LLARELERVDSG------YRSAMSVQSSLVMHPIY-----AYGSEEQRQKYLPQLAKGEL 173
L+AR L ++ G YR A+S +L +H ++ + GSEEQ K+ P ++
Sbjct: 89 LIARRLGWLEDGRELGYAYR-ALSGDVALNIHRVFVRALRSLGSEEQIAKWDPLCKNIQI 147
Query: 174 LGCFGLTEPNSGSDPSSMETRAHYNSSNKSY-----TLNGTKTW---ITNSPMADLFVVW 225
+ + TE G+ +ET A Y+++ + + TL TK W + S L
Sbjct: 148 IATYAQTELGHGTYLQGLETEATYDAATQEFVIHSPTLTATKWWPGDLGRSATHALVQAQ 207
Query: 226 ARCEDG---------CIRGFLLEKGMRGLSAPRIQGKFSLRASATGMIIMDGVEVPEENV 276
C IR + G+ I K + G + ++ V VP EN+
Sbjct: 208 LICSGARRGMHAFIVPIRSLQDHTPLPGIIIGDIGPKMDFDQTDNGFLQLNHVRVPRENM 267
Query: 277 L 277
L
Sbjct: 268 L 268
>gi|21361458 Rho guanine nucleotide exchange factor (GEF) 17 [Homo
sapiens]
Length = 2063
Score = 36.6 bits (83), Expect = 0.046
Identities = 27/86 (31%), Positives = 37/86 (43%), Gaps = 9/86 (10%)
Query: 158 EEQRQKYLPQLAKGELLGCFGLTEPNSGSDPSSMETRAHYNSSNKSYTLNGTKTWITNSP 217
EEQ +LP L G FG P S M+ RA SS+ S+T + ++ P
Sbjct: 1684 EEQEPGFLP------LSGSFG---PGGPCGTSPMDGRALRRSSHGSFTRGSLEDLLSVDP 1734
Query: 218 MADLFVVWARCEDGCIRGFLLEKGMR 243
A VW EDGC+ + +R
Sbjct: 1735 EAYQSSVWLGTEDGCVHVYQSSDSIR 1760
>gi|30089974 acyl-Coenzyme A oxidase 1 isoform b [Homo sapiens]
Length = 660
Score = 34.7 bits (78), Expect = 0.18
Identities = 32/149 (21%), Positives = 59/149 (39%), Gaps = 17/149 (11%)
Query: 146 SLVMHPIYAYGSEEQRQKYLPQLAKGELLGCFGLTEPNSGSDPSSMETRAHYNSSNKSYT 205
S+ + + G+ Q++K+L +++G + TE G+ +ET A Y+ + +
Sbjct: 105 SMFIPTLLNQGTTAQKEKWLLSSKGLQIIGTYAQTEMGHGTHLRGLETTATYDPETQEFI 164
Query: 206 LNGT-----KTW---ITNSPMADLFVVWARCEDGC---------IRGFLLEKGMRGLSAP 248
LN K W + + + + + C IR K + G++
Sbjct: 165 LNSPTVTSIKWWPGGLGKTSNHAIVLAQLITKGKCYGLHAFIVPIREIGTHKPLPGITVG 224
Query: 249 RIQGKFSLRASATGMIIMDGVEVPEENVL 277
I KF G + MD +P EN+L
Sbjct: 225 DIGPKFGYDEIDNGYLKMDNHRIPRENML 253
>gi|30089972 acyl-Coenzyme A oxidase 1 isoform a [Homo sapiens]
Length = 660
Score = 33.9 bits (76), Expect = 0.30
Identities = 32/162 (19%), Positives = 61/162 (37%), Gaps = 17/162 (10%)
Query: 133 VDSGYRSAMSVQSSLVMHPIYAYGSEEQRQKYLPQLAKGELLGCFGLTEPNSGSDPSSME 192
V G + + + + + + EQ++++ E++G + TE G+ +E
Sbjct: 92 VHRGRPEPLDLHLGMFLPTLLHQATAEQQERFFMPAWNLEIIGTYAQTEMGHGTHLRGLE 151
Query: 193 TRAHYNSSNKSYTLNGT-----KTW---ITNSPMADLFVVWARCEDGC---------IRG 235
T A Y+ + + LN K W + + + + + C IR
Sbjct: 152 TTATYDPETQEFILNSPTVTSIKWWPGGLGKTSNHAIVLAQLITKGKCYGLHAFIVPIRE 211
Query: 236 FLLEKGMRGLSAPRIQGKFSLRASATGMIIMDGVEVPEENVL 277
K + G++ I KF G + MD +P EN+L
Sbjct: 212 IGTHKPLPGITVGDIGPKFGYDEIDNGYLKMDNHRIPRENML 253
>gi|30410846 APG4 autophagy 4 homolog C isoform 8 [Homo sapiens]
Length = 458
Score = 32.3 bits (72), Expect = 0.87
Identities = 27/95 (28%), Positives = 45/95 (47%), Gaps = 9/95 (9%)
Query: 10 LLSRGPGLHVL-RTWVSSAAQTEKGGRTQSQLAKSSRP-EFDWQDPLVLEEQLTTDEILI 67
LL++G LH L R W A + ++S + + + ++ L E + T I +
Sbjct: 119 LLAQGLILHFLGRAWTWPDALNIENSDSESWTSHTVKKFTASFEASLSGEREFKTPTISL 178
Query: 68 RDTFRTYCQERLMPRILLANRNEVFHREIISEMGE 102
++T Y + M RNEV+HR+IIS G+
Sbjct: 179 KETIGKYSDDHEM-------RNEVYHRKIISWFGD 206
>gi|30410844 APG4 autophagy 4 homolog C isoform 7 [Homo sapiens]
Length = 458
Score = 32.3 bits (72), Expect = 0.87
Identities = 27/95 (28%), Positives = 45/95 (47%), Gaps = 9/95 (9%)
Query: 10 LLSRGPGLHVL-RTWVSSAAQTEKGGRTQSQLAKSSRP-EFDWQDPLVLEEQLTTDEILI 67
LL++G LH L R W A + ++S + + + ++ L E + T I +
Sbjct: 119 LLAQGLILHFLGRAWTWPDALNIENSDSESWTSHTVKKFTASFEASLSGEREFKTPTISL 178
Query: 68 RDTFRTYCQERLMPRILLANRNEVFHREIISEMGE 102
++T Y + M RNEV+HR+IIS G+
Sbjct: 179 KETIGKYSDDHEM-------RNEVYHRKIISWFGD 206
>gi|163310725 ER degradation enhancer, mannosidase alpha-like 3
[Homo sapiens]
Length = 932
Score = 32.0 bits (71), Expect = 1.1
Identities = 26/105 (24%), Positives = 43/105 (40%), Gaps = 23/105 (21%)
Query: 18 HVLRTWVSSAAQTEKGGRTQSQLAKSSRPEFDW----------QDPL-----------VL 56
H+L W+S+ Q+ T S+ + FDW DPL V+
Sbjct: 494 HLLPLWLSTTNQSISKKNTTSEYTELDDSNFDWTCPNTQILFPNDPLYAQSIREPLKNVV 553
Query: 57 EEQLTTDEILIRDTFRTYCQERLMPRILLANRNEVFHREIISEMG 101
++ I + ++FR+ + L R +A E H EI+ +MG
Sbjct: 554 DKSCPRGIIRVEESFRSGAKPPLRARDFMATNPE--HLEILKKMG 596
>gi|7657104 G0/G1switch 2 [Homo sapiens]
Length = 103
Score = 31.6 bits (70), Expect = 1.5
Identities = 27/101 (26%), Positives = 45/101 (44%), Gaps = 18/101 (17%)
Query: 317 LDRMQFGVPLARNQLIQKKLADMLTEITLGLHACL---QLG-------------RLKDQD 360
++ +Q +PLA+ + QK+ M+ LG L LG RL+DQ+
Sbjct: 1 METVQELIPLAKEMMAQKRKGKMVKLYVLGSVLALFGVVLGLMETVCSPFTAARRLRDQE 60
Query: 361 KAAPEMVSLLKRNNCGKAL--DIARQARDMLGGNGISDEYH 399
A E+ + L+R K + +Q +LGG +S+ H
Sbjct: 61 AAVAELQAALERQALQKQALQEKGKQQDTVLGGRALSNRQH 101
Database: hs.faa
Posted date: Aug 4, 2009 4:42 PM
Number of letters in database: 18,247,518
Number of sequences in database: 37,866
Lambda K H
0.319 0.135 0.400
Gapped
Lambda K H
0.267 0.0410 0.140
Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Hits to DB: 15,791,957
Number of Sequences: 37866
Number of extensions: 670906
Number of successful extensions: 1467
Number of sequences better than 10.0: 30
Number of HSP's better than 10.0 without gapping: 28
Number of HSP's successfully gapped in prelim test: 4
Number of HSP's that attempted gapping in prelim test: 1378
Number of HSP's gapped (non-prelim): 37
length of query: 438
length of database: 18,247,518
effective HSP length: 105
effective length of query: 333
effective length of database: 14,271,588
effective search space: 4752438804
effective search space used: 4752438804
T: 11
A: 40
X1: 16 ( 7.4 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 41 (21.8 bits)
S2: 63 (28.9 bits)
Search results were obtained with NCBI BLAST and RefSeq entries.
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Guide to the Human Genome
Copyright © 2010 by Stewart Scherer. All rights reserved.