Guide to the Human Genome
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Search of human proteins with 4503771

BLASTP 2.2.11 [Jun-05-2005]


Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer, 
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), 
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs",  Nucleic Acids Res. 25:3389-3402.

Query= gi|4503771 farnesyltransferase, CAAX box, alpha isoform a [Homo
sapiens]
         (379 letters)

Database: hs.faa 
           37,866 sequences; 18,247,518 total letters

Searching..................................................done

                                                                 Score    E
Sequences producing significant alignments:                      (bits) Value

gi|4503771 farnesyltransferase, CAAX box, alpha isoform a [Homo ...   785   0.0  
gi|66882524 farnesyltransferase, CAAX box, alpha isoform b [Homo...   585   e-167
gi|66882532 farnesyltransferase, CAAX box, alpha isoform c [Homo...   532   e-151
gi|53828918 Rab geranylgeranyltransferase alpha [Homo sapiens]         80   4e-15
gi|33469951 Rab geranylgeranyltransferase alpha [Homo sapiens]         80   4e-15
gi|153792604 protein prenyltransferase alpha subunit repeat cont...    46   6e-05
gi|38683860 insulin receptor substrate 2 [Homo sapiens]                40   0.003
gi|5032187 transducer of ERBB2, 1 [Homo sapiens]                       39   0.006
gi|239757043 PREDICTED: functional smad suppressing element 18 [...    37   0.029
gi|4503825 frizzled 1 [Homo sapiens]                                   37   0.038
gi|9257222 forkhead box O1 [Homo sapiens]                              37   0.038
gi|239751555 PREDICTED: functional smad suppressing element 18 [...    37   0.038
gi|239746067 PREDICTED: functional smad suppressing element 18 [...    37   0.038
gi|195972805 myocyte enhancer factor 2A isoform 4 [Homo sapiens]       36   0.050
gi|195972803 myocyte enhancer factor 2A isoform 3 [Homo sapiens]       36   0.050
gi|195972801 myocyte enhancer factor 2A isoform 2 [Homo sapiens]       36   0.050
gi|195972799 myocyte enhancer factor 2A isoform 1 [Homo sapiens]       36   0.050
gi|189491742 ataxin 7 isoform b [Homo sapiens]                         36   0.050
gi|4506797 ataxin 7 isoform a [Homo sapiens]                           36   0.050
gi|147902746 MEX3A protein [Homo sapiens]                              36   0.050
gi|23503317 coiled-coil domain containing 96 [Homo sapiens]            36   0.050
gi|239757409 PREDICTED: similar to zinc finger protein 208 [Homo...    35   0.085
gi|239746371 PREDICTED: similar to zinc finger protein 208 [Homo...    35   0.085
gi|18426913 drebrin 1 isoform b [Homo sapiens]                         35   0.085
gi|18426915 drebrin 1 isoform a [Homo sapiens]                         35   0.085
gi|45827729 scribble isoform b [Homo sapiens]                          35   0.085
gi|45827731 scribble isoform a [Homo sapiens]                          35   0.085
gi|222144283 hypothetical protein LOC65998 [Homo sapiens]              35   0.11 
gi|4507877 vinculin isoform VCL [Homo sapiens]                         35   0.11 
gi|7669550 vinculin isoform meta-VCL [Homo sapiens]                    35   0.11 

>gi|4503771 farnesyltransferase, CAAX box, alpha isoform a [Homo
           sapiens]
          Length = 379

 Score =  785 bits (2028), Expect = 0.0
 Identities = 379/379 (100%), Positives = 379/379 (100%)

Query: 1   MAATEGVGEAAQGGEPGQPAQPPPQPHPPPPQQQHKEEMAAEAGEAVASPMDDGFVSLDS 60
           MAATEGVGEAAQGGEPGQPAQPPPQPHPPPPQQQHKEEMAAEAGEAVASPMDDGFVSLDS
Sbjct: 1   MAATEGVGEAAQGGEPGQPAQPPPQPHPPPPQQQHKEEMAAEAGEAVASPMDDGFVSLDS 60

Query: 61  PSYVLYRDRAEWADIDPVPQNDGPNPVVQIIYSDKFRDVYDYFRAVLQRDERSERAFKLT 120
           PSYVLYRDRAEWADIDPVPQNDGPNPVVQIIYSDKFRDVYDYFRAVLQRDERSERAFKLT
Sbjct: 61  PSYVLYRDRAEWADIDPVPQNDGPNPVVQIIYSDKFRDVYDYFRAVLQRDERSERAFKLT 120

Query: 121 RDAIELNAANYTVWHFRRVLLKSLQKDLHEEMNYITAIIEEQPKNYQVWHHRRVLVEWLR 180
           RDAIELNAANYTVWHFRRVLLKSLQKDLHEEMNYITAIIEEQPKNYQVWHHRRVLVEWLR
Sbjct: 121 RDAIELNAANYTVWHFRRVLLKSLQKDLHEEMNYITAIIEEQPKNYQVWHHRRVLVEWLR 180

Query: 181 DPSQELEFIADILNQDAKNYHAWQHRQWVIQEFKLWDNELQYVDQLLKEDVRNNSVWNQR 240
           DPSQELEFIADILNQDAKNYHAWQHRQWVIQEFKLWDNELQYVDQLLKEDVRNNSVWNQR
Sbjct: 181 DPSQELEFIADILNQDAKNYHAWQHRQWVIQEFKLWDNELQYVDQLLKEDVRNNSVWNQR 240

Query: 241 YFVISNTTGYNDRAVLEREVQYTLEMIKLVPHNESAWNYLKGILQDRGLSKYPNLLNQLL 300
           YFVISNTTGYNDRAVLEREVQYTLEMIKLVPHNESAWNYLKGILQDRGLSKYPNLLNQLL
Sbjct: 241 YFVISNTTGYNDRAVLEREVQYTLEMIKLVPHNESAWNYLKGILQDRGLSKYPNLLNQLL 300

Query: 301 DLQPSHSSPYLIAFLVDIYEDMLENQCDNKEDILNKALELCEILAKEKDTIRKEYWRYIG 360
           DLQPSHSSPYLIAFLVDIYEDMLENQCDNKEDILNKALELCEILAKEKDTIRKEYWRYIG
Sbjct: 301 DLQPSHSSPYLIAFLVDIYEDMLENQCDNKEDILNKALELCEILAKEKDTIRKEYWRYIG 360

Query: 361 RSLQSKHSTENDSPTNVQQ 379
           RSLQSKHSTENDSPTNVQQ
Sbjct: 361 RSLQSKHSTENDSPTNVQQ 379


>gi|66882524 farnesyltransferase, CAAX box, alpha isoform b [Homo
           sapiens]
          Length = 288

 Score =  585 bits (1507), Expect = e-167
 Identities = 283/283 (100%), Positives = 283/283 (100%)

Query: 97  RDVYDYFRAVLQRDERSERAFKLTRDAIELNAANYTVWHFRRVLLKSLQKDLHEEMNYIT 156
           RDVYDYFRAVLQRDERSERAFKLTRDAIELNAANYTVWHFRRVLLKSLQKDLHEEMNYIT
Sbjct: 6   RDVYDYFRAVLQRDERSERAFKLTRDAIELNAANYTVWHFRRVLLKSLQKDLHEEMNYIT 65

Query: 157 AIIEEQPKNYQVWHHRRVLVEWLRDPSQELEFIADILNQDAKNYHAWQHRQWVIQEFKLW 216
           AIIEEQPKNYQVWHHRRVLVEWLRDPSQELEFIADILNQDAKNYHAWQHRQWVIQEFKLW
Sbjct: 66  AIIEEQPKNYQVWHHRRVLVEWLRDPSQELEFIADILNQDAKNYHAWQHRQWVIQEFKLW 125

Query: 217 DNELQYVDQLLKEDVRNNSVWNQRYFVISNTTGYNDRAVLEREVQYTLEMIKLVPHNESA 276
           DNELQYVDQLLKEDVRNNSVWNQRYFVISNTTGYNDRAVLEREVQYTLEMIKLVPHNESA
Sbjct: 126 DNELQYVDQLLKEDVRNNSVWNQRYFVISNTTGYNDRAVLEREVQYTLEMIKLVPHNESA 185

Query: 277 WNYLKGILQDRGLSKYPNLLNQLLDLQPSHSSPYLIAFLVDIYEDMLENQCDNKEDILNK 336
           WNYLKGILQDRGLSKYPNLLNQLLDLQPSHSSPYLIAFLVDIYEDMLENQCDNKEDILNK
Sbjct: 186 WNYLKGILQDRGLSKYPNLLNQLLDLQPSHSSPYLIAFLVDIYEDMLENQCDNKEDILNK 245

Query: 337 ALELCEILAKEKDTIRKEYWRYIGRSLQSKHSTENDSPTNVQQ 379
           ALELCEILAKEKDTIRKEYWRYIGRSLQSKHSTENDSPTNVQQ
Sbjct: 246 ALELCEILAKEKDTIRKEYWRYIGRSLQSKHSTENDSPTNVQQ 288


>gi|66882532 farnesyltransferase, CAAX box, alpha isoform c [Homo
           sapiens]
          Length = 312

 Score =  532 bits (1370), Expect = e-151
 Identities = 278/380 (73%), Positives = 289/380 (76%), Gaps = 69/380 (18%)

Query: 1   MAATEGVGEAAQGGEPGQPAQPPPQPHPPPPQQQHKEEMAAEAGEAVASPMDDGFVSLDS 60
           MAATEGVGEAAQGGEPGQPAQP        P Q H      +  E +A+   +   S   
Sbjct: 1   MAATEGVGEAAQGGEPGQPAQP--------PPQPHPPPPQQQHKEEMAAEAGEAVAS--- 49

Query: 61  PSYVLYRDRAEWADIDPVPQNDGPNPVVQIIYSDKFRDVYDYFRAVLQRDERSERAFKLT 120
                             P +DG                                     
Sbjct: 50  ------------------PMDDG------------------------------------- 54

Query: 121 RDAIELNAANYTVW-HFRRVLLKSLQKDLHEEMNYITAIIEEQPKNYQVWHHRRVLVEWL 179
              + L++ +Y ++ HFRRVLLKSLQKDLHEEMNYITAIIEEQPKNYQVWHHRRVLVEWL
Sbjct: 55  --FVSLDSPSYVLYRHFRRVLLKSLQKDLHEEMNYITAIIEEQPKNYQVWHHRRVLVEWL 112

Query: 180 RDPSQELEFIADILNQDAKNYHAWQHRQWVIQEFKLWDNELQYVDQLLKEDVRNNSVWNQ 239
           RDPSQELEFIADILNQDAKNYHAWQHRQWVIQEFKLWDNELQYVDQLLKEDVRNNSVWNQ
Sbjct: 113 RDPSQELEFIADILNQDAKNYHAWQHRQWVIQEFKLWDNELQYVDQLLKEDVRNNSVWNQ 172

Query: 240 RYFVISNTTGYNDRAVLEREVQYTLEMIKLVPHNESAWNYLKGILQDRGLSKYPNLLNQL 299
           RYFVISNTTGYNDRAVLEREVQYTLEMIKLVPHNESAWNYLKGILQDRGLSKYPNLLNQL
Sbjct: 173 RYFVISNTTGYNDRAVLEREVQYTLEMIKLVPHNESAWNYLKGILQDRGLSKYPNLLNQL 232

Query: 300 LDLQPSHSSPYLIAFLVDIYEDMLENQCDNKEDILNKALELCEILAKEKDTIRKEYWRYI 359
           LDLQPSHSSPYLIAFLVDIYEDMLENQCDNKEDILNKALELCEILAKEKDTIRKEYWRYI
Sbjct: 233 LDLQPSHSSPYLIAFLVDIYEDMLENQCDNKEDILNKALELCEILAKEKDTIRKEYWRYI 292

Query: 360 GRSLQSKHSTENDSPTNVQQ 379
           GRSLQSKHSTENDSPTNVQQ
Sbjct: 293 GRSLQSKHSTENDSPTNVQQ 312


>gi|53828918 Rab geranylgeranyltransferase alpha [Homo sapiens]
          Length = 567

 Score = 79.7 bits (195), Expect = 4e-15
 Identities = 56/197 (28%), Positives = 93/197 (47%), Gaps = 20/197 (10%)

Query: 108 QRDERSERAFKLTRDAIELNAANYTVWHFRRVLLKSL--QKDLHE-------EMNYITAI 158
           Q  E  E   +LT   +  N    T+W+ RR +L+ L  QK   E       E+ ++ + 
Sbjct: 40  QAGELDESVLELTSQILGANPDFATLWNCRREVLQQLETQKSPEELAALVKAELGFLESC 99

Query: 159 IEEQPKNYQVWHHRRVLVEWLRDP--SQELEFIADILNQDAKNYHAWQHRQWVIQEFKLW 216
           +   PK+Y  WHHR  L+  L +P  ++ELE  A  L  D +N+H W +R++V  +  + 
Sbjct: 100 LRVNPKSYGTWHHRCWLLGRLPEPNWTRELELCARFLEVDERNFHCWDYRRFVATQAAVP 159

Query: 217 D-NELQYVDQLLKEDVRNNSVWNQRYFVI--------SNTTGYNDRAVLEREVQYTLEMI 267
              EL + D L+  +  N S W+ R  ++        S   G     VL +E++      
Sbjct: 160 PAEELAFTDSLITRNFSNYSSWHYRSCLLPQLHPQPDSGPQGRLPEDVLLKELELVQNAF 219

Query: 268 KLVPHNESAWNYLKGIL 284
              P+++SAW Y + +L
Sbjct: 220 FTDPNDQSAWFYHRWLL 236


>gi|33469951 Rab geranylgeranyltransferase alpha [Homo sapiens]
          Length = 567

 Score = 79.7 bits (195), Expect = 4e-15
 Identities = 56/197 (28%), Positives = 93/197 (47%), Gaps = 20/197 (10%)

Query: 108 QRDERSERAFKLTRDAIELNAANYTVWHFRRVLLKSL--QKDLHE-------EMNYITAI 158
           Q  E  E   +LT   +  N    T+W+ RR +L+ L  QK   E       E+ ++ + 
Sbjct: 40  QAGELDESVLELTSQILGANPDFATLWNCRREVLQQLETQKSPEELAALVKAELGFLESC 99

Query: 159 IEEQPKNYQVWHHRRVLVEWLRDP--SQELEFIADILNQDAKNYHAWQHRQWVIQEFKLW 216
           +   PK+Y  WHHR  L+  L +P  ++ELE  A  L  D +N+H W +R++V  +  + 
Sbjct: 100 LRVNPKSYGTWHHRCWLLGRLPEPNWTRELELCARFLEVDERNFHCWDYRRFVATQAAVP 159

Query: 217 D-NELQYVDQLLKEDVRNNSVWNQRYFVI--------SNTTGYNDRAVLEREVQYTLEMI 267
              EL + D L+  +  N S W+ R  ++        S   G     VL +E++      
Sbjct: 160 PAEELAFTDSLITRNFSNYSSWHYRSCLLPQLHPQPDSGPQGRLPEDVLLKELELVQNAF 219

Query: 268 KLVPHNESAWNYLKGIL 284
              P+++SAW Y + +L
Sbjct: 220 FTDPNDQSAWFYHRWLL 236


>gi|153792604 protein prenyltransferase alpha subunit repeat
           containing 1 [Homo sapiens]
          Length = 402

 Score = 45.8 bits (107), Expect = 6e-05
 Identities = 53/240 (22%), Positives = 99/240 (41%), Gaps = 48/240 (20%)

Query: 107 LQRDERSERAFKLTRDAIELNAANYTVWHFRRVLLKSLQKDLHEEMNYITAIIEEQPKNY 166
           L RDE  +    +T   + LN    T W+ R+ L+ S   +  ++++     + + PK+ 
Sbjct: 82  LNRDELID----VTCTLLLLNPDFTTAWNVRKELILSGTLNPIKDLHLGKLALTKFPKSP 137

Query: 167 QVWHHRR-VLVEWLRDPS-----------------------QELEFIADILNQDAKNYHA 202
           + W HRR VL + +++ S                       +E+E   +   +   NY+A
Sbjct: 138 ETWIHRRWVLQQLIQETSLPSFVTKGNLGTIPTERAQRLIQEEMEVCGEAAGRYPSNYNA 197

Query: 203 WQHRQWVIQ-----EFKLWDNELQYVDQLLKEDVRNNSVWNQRYFVISNTTGYN--DRAV 255
           W HR WV+Q     + K+  +EL          V ++S ++ R F++ +       D +V
Sbjct: 198 WSHRIWVLQHLAKLDVKILLDELSSTKHWASMHVSDHSGFHYRQFLLKSLISQTVIDSSV 257

Query: 256 LEREVQYTLEMIKLVPHNESAWNYLKGILQDRGLSKYPNLLNQ-------LLDLQPSHSS 308
           +E+      E   + P +E A      +  +      P+LL +       L+D  P H +
Sbjct: 258 MEQN-PLRSEPALVPPKDEEA-----AVSTEEPRINLPHLLEEEVEFSTDLIDSYPGHET 311


>gi|38683860 insulin receptor substrate 2 [Homo sapiens]
          Length = 1338

 Score = 40.0 bits (92), Expect = 0.003
 Identities = 22/61 (36%), Positives = 29/61 (47%), Gaps = 3/61 (4%)

Query: 2   AATEGVGEAAQGGEPGQPAQPPPQPHPPPPQQQHK---EEMAAEAGEAVASPMDDGFVSL 58
           AAT     ++  G       PPP PHPP P   H    +  ++ +  A  SP D GF+SL
Sbjct: 441 AATSPGSLSSSSGHGSGSYPPPPGPHPPLPHPLHHGPGQRPSSGSASASGSPSDPGFMSL 500

Query: 59  D 59
           D
Sbjct: 501 D 501


>gi|5032187 transducer of ERBB2, 1 [Homo sapiens]
          Length = 345

 Score = 39.3 bits (90), Expect = 0.006
 Identities = 18/36 (50%), Positives = 24/36 (66%), Gaps = 2/36 (5%)

Query: 6   GVGEAAQGGEPGQPAQPPPQPHPPPPQQQHKEEMAA 41
           G+G   Q  +  QPAQPPP   PPPPQQQ +++ +A
Sbjct: 233 GLGSQQQPQQQQQPAQPPPP--PPPPQQQQQQKTSA 266



 Score = 29.6 bits (65), Expect = 4.7
 Identities = 15/43 (34%), Positives = 22/43 (51%), Gaps = 2/43 (4%)

Query: 1   MAATEGVGEAAQGGEPGQPAQPPPQPHPPPPQQQHKEEMAAEA 43
           M +  G+G  +Q  +  Q  Q P QP PPPP  Q +++    A
Sbjct: 226 MHSLYGLGLGSQ--QQPQQQQQPAQPPPPPPPPQQQQQQKTSA 266


>gi|239757043 PREDICTED: functional smad suppressing element 18
           [Homo sapiens]
          Length = 996

 Score = 37.0 bits (84), Expect = 0.029
 Identities = 17/44 (38%), Positives = 22/44 (50%), Gaps = 3/44 (6%)

Query: 13  GGEPGQPAQPPPQPHPPPP---QQQHKEEMAAEAGEAVASPMDD 53
           G E   PA PPP P PPPP   Q  H   + +  G + + P +D
Sbjct: 687 GSERHHPAPPPPPPPPPPPPLAQHPHHRGLLSPGGTSCSYPSED 730


>gi|4503825 frizzled 1 [Homo sapiens]
          Length = 647

 Score = 36.6 bits (83), Expect = 0.038
 Identities = 19/42 (45%), Positives = 22/42 (52%)

Query: 6   GVGEAAQGGEPGQPAQPPPQPHPPPPQQQHKEEMAAEAGEAV 47
           GV   A G  PGQ   P  QP PPP QQQ  ++   E G +V
Sbjct: 69  GVRAQAAGQGPGQGPGPGQQPPPPPQQQQSGQQYNGERGISV 110


>gi|9257222 forkhead box O1 [Homo sapiens]
          Length = 655

 Score = 36.6 bits (83), Expect = 0.038
 Identities = 21/49 (42%), Positives = 22/49 (44%)

Query: 2   AATEGVGEAAQGGEPGQPAQPPPQPHPPPPQQQHKEEMAAEAGEAVASP 50
           AAT G+    QG E G     PPQP PP P  QH     A AG     P
Sbjct: 101 AATGGLCGDFQGPEAGCLHPAPPQPPPPGPLSQHPPVPPAAAGPLAGQP 149


>gi|239751555 PREDICTED: functional smad suppressing element 18
           [Homo sapiens]
          Length = 1252

 Score = 36.6 bits (83), Expect = 0.038
 Identities = 17/44 (38%), Positives = 21/44 (47%), Gaps = 3/44 (6%)

Query: 13  GGEPGQPAQPPPQPHPPPP---QQQHKEEMAAEAGEAVASPMDD 53
           G E   PA PPP P PPPP   Q  H   + +  G +   P +D
Sbjct: 687 GSERHHPAPPPPPPPPPPPPLAQHPHHRGLLSPGGTSCCYPSED 730


>gi|239746067 PREDICTED: functional smad suppressing element 18
           [Homo sapiens]
          Length = 1252

 Score = 36.6 bits (83), Expect = 0.038
 Identities = 17/44 (38%), Positives = 21/44 (47%), Gaps = 3/44 (6%)

Query: 13  GGEPGQPAQPPPQPHPPPP---QQQHKEEMAAEAGEAVASPMDD 53
           G E   PA PPP P PPPP   Q  H   + +  G +   P +D
Sbjct: 687 GSERHHPAPPPPPPPPPPPPLAQHPHHRGLLSPGGTSCCYPSED 730


>gi|195972805 myocyte enhancer factor 2A isoform 4 [Homo sapiens]
          Length = 429

 Score = 36.2 bits (82), Expect = 0.050
 Identities = 29/83 (34%), Positives = 40/83 (48%), Gaps = 18/83 (21%)

Query: 6   GVGEAAQGGEPGQPAQPPPQPHPPPPQQQHKEEMAAEAGEAVASPMDDGFVSLDSPSYVL 65
           G  +  Q  +  QP  PPPQP P PPQ Q ++EM         SP+D   +S  S SY  
Sbjct: 340 GFQQQQQQQQQQQPP-PPPQPQPQPPQPQPRQEMG-------RSPVDS--LSSSSSSY-- 387

Query: 66  YRDRAEWADIDPVPQNDGPNPVV 88
             D ++  D    P+ D  +P+V
Sbjct: 388 --DGSDRED----PRGDFHSPIV 404


>gi|195972803 myocyte enhancer factor 2A isoform 3 [Homo sapiens]
          Length = 437

 Score = 36.2 bits (82), Expect = 0.050
 Identities = 29/83 (34%), Positives = 40/83 (48%), Gaps = 18/83 (21%)

Query: 6   GVGEAAQGGEPGQPAQPPPQPHPPPPQQQHKEEMAAEAGEAVASPMDDGFVSLDSPSYVL 65
           G  +  Q  +  QP  PPPQP P PPQ Q ++EM         SP+D   +S  S SY  
Sbjct: 348 GFQQQQQQQQQQQPP-PPPQPQPQPPQPQPRQEMG-------RSPVDS--LSSSSSSY-- 395

Query: 66  YRDRAEWADIDPVPQNDGPNPVV 88
             D ++  D    P+ D  +P+V
Sbjct: 396 --DGSDRED----PRGDFHSPIV 412


>gi|195972801 myocyte enhancer factor 2A isoform 2 [Homo sapiens]
          Length = 497

 Score = 36.2 bits (82), Expect = 0.050
 Identities = 29/83 (34%), Positives = 40/83 (48%), Gaps = 18/83 (21%)

Query: 6   GVGEAAQGGEPGQPAQPPPQPHPPPPQQQHKEEMAAEAGEAVASPMDDGFVSLDSPSYVL 65
           G  +  Q  +  QP  PPPQP P PPQ Q ++EM         SP+D   +S  S SY  
Sbjct: 408 GFQQQQQQQQQQQPP-PPPQPQPQPPQPQPRQEMG-------RSPVDS--LSSSSSSY-- 455

Query: 66  YRDRAEWADIDPVPQNDGPNPVV 88
             D ++  D    P+ D  +P+V
Sbjct: 456 --DGSDRED----PRGDFHSPIV 472


>gi|195972799 myocyte enhancer factor 2A isoform 1 [Homo sapiens]
          Length = 499

 Score = 36.2 bits (82), Expect = 0.050
 Identities = 29/83 (34%), Positives = 40/83 (48%), Gaps = 18/83 (21%)

Query: 6   GVGEAAQGGEPGQPAQPPPQPHPPPPQQQHKEEMAAEAGEAVASPMDDGFVSLDSPSYVL 65
           G  +  Q  +  QP  PPPQP P PPQ Q ++EM         SP+D   +S  S SY  
Sbjct: 410 GFQQQQQQQQQQQPP-PPPQPQPQPPQPQPRQEMG-------RSPVDS--LSSSSSSY-- 457

Query: 66  YRDRAEWADIDPVPQNDGPNPVV 88
             D ++  D    P+ D  +P+V
Sbjct: 458 --DGSDRED----PRGDFHSPIV 474


>gi|189491742 ataxin 7 isoform b [Homo sapiens]
          Length = 945

 Score = 36.2 bits (82), Expect = 0.050
 Identities = 29/95 (30%), Positives = 39/95 (41%), Gaps = 16/95 (16%)

Query: 2   AATEGVGEAAQGGEPGQPAQ---PPPQP----HPPPPQQQHKEEMAAEAGEAVASPMDDG 54
           AA  G   AA   +  Q  Q   PPPQP    HPPPP ++ + E   + G   AS     
Sbjct: 18  AAAGGAAAAAARQQQQQQQQQQPPPPQPQRQQHPPPPPRRTRPE---DGGPGAASTSAAA 74

Query: 55  FVS------LDSPSYVLYRDRAEWADIDPVPQNDG 83
             +      L SP  +L +    W +   +P  DG
Sbjct: 75  MATVGERRPLPSPEVMLGQSWNLWVEASKLPGKDG 109



 Score = 32.7 bits (73), Expect = 0.55
 Identities = 25/75 (33%), Positives = 34/75 (45%), Gaps = 7/75 (9%)

Query: 18  QPAQPPPQPHPPPP---QQQHKEE---MAAEAGEAVASPMDDGFVSLDSPSYVLYRDRAE 71
           QP QP   PHP PP   Q+ H+     + +E+   VAS       SL  P     +    
Sbjct: 406 QPPQPLRDPHPAPPRTSQEPHQNPHGVIPSESKPFVASKPKPHTPSLPRPPGCPAQQGGS 465

Query: 72  WADIDPVPQNDGPNP 86
            A IDP P ++ P+P
Sbjct: 466 -APIDPPPVHESPHP 479



 Score = 30.8 bits (68), Expect = 2.1
 Identities = 16/39 (41%), Positives = 20/39 (51%), Gaps = 5/39 (12%)

Query: 10  AAQGGEPGQPAQPPP---QPHPPPPQQQHKEEMAAEAGE 45
           A QGG    P  PPP    PHPP P  +    +++E GE
Sbjct: 460 AQQGGSA--PIDPPPVHESPHPPLPATEPASRLSSEEGE 496


>gi|4506797 ataxin 7 isoform a [Homo sapiens]
          Length = 892

 Score = 36.2 bits (82), Expect = 0.050
 Identities = 29/95 (30%), Positives = 39/95 (41%), Gaps = 16/95 (16%)

Query: 2   AATEGVGEAAQGGEPGQPAQ---PPPQP----HPPPPQQQHKEEMAAEAGEAVASPMDDG 54
           AA  G   AA   +  Q  Q   PPPQP    HPPPP ++ + E   + G   AS     
Sbjct: 18  AAAGGAAAAAARQQQQQQQQQQPPPPQPQRQQHPPPPPRRTRPE---DGGPGAASTSAAA 74

Query: 55  FVS------LDSPSYVLYRDRAEWADIDPVPQNDG 83
             +      L SP  +L +    W +   +P  DG
Sbjct: 75  MATVGERRPLPSPEVMLGQSWNLWVEASKLPGKDG 109



 Score = 32.7 bits (73), Expect = 0.55
 Identities = 25/75 (33%), Positives = 34/75 (45%), Gaps = 7/75 (9%)

Query: 18  QPAQPPPQPHPPPP---QQQHKEE---MAAEAGEAVASPMDDGFVSLDSPSYVLYRDRAE 71
           QP QP   PHP PP   Q+ H+     + +E+   VAS       SL  P     +    
Sbjct: 406 QPPQPLRDPHPAPPRTSQEPHQNPHGVIPSESKPFVASKPKPHTPSLPRPPGCPAQQGGS 465

Query: 72  WADIDPVPQNDGPNP 86
            A IDP P ++ P+P
Sbjct: 466 -APIDPPPVHESPHP 479



 Score = 30.8 bits (68), Expect = 2.1
 Identities = 16/39 (41%), Positives = 20/39 (51%), Gaps = 5/39 (12%)

Query: 10  AAQGGEPGQPAQPPP---QPHPPPPQQQHKEEMAAEAGE 45
           A QGG    P  PPP    PHPP P  +    +++E GE
Sbjct: 460 AQQGGSA--PIDPPPVHESPHPPLPATEPASRLSSEEGE 496


>gi|147902746 MEX3A protein [Homo sapiens]
          Length = 520

 Score = 36.2 bits (82), Expect = 0.050
 Identities = 17/26 (65%), Positives = 17/26 (65%), Gaps = 2/26 (7%)

Query: 8  GEAAQGGEPGQPAQP--PPQPHPPPP 31
          GE   GG  G PAQP  PPQP PPPP
Sbjct: 59 GEDGGGGGGGAPAQPAAPPQPAPPPP 84



 Score = 35.0 bits (79), Expect = 0.11
 Identities = 17/43 (39%), Positives = 18/43 (41%)

Query: 8   GEAAQGGEPGQPAQPPPQPHPPPPQQQHKEEMAAEAGEAVASP 50
           G    GG P QPA PP    PPPP        AA A +    P
Sbjct: 62  GGGGGGGAPAQPAAPPQPAPPPPPAAPPAAPTAAPAAQTPQPP 104



 Score = 30.0 bits (66), Expect = 3.6
 Identities = 19/77 (24%), Positives = 28/77 (36%)

Query: 6   GVGEAAQGGEPGQPAQPPPQPHPPPPQQQHKEEMAAEAGEAVASPMDDGFVSLDSPSYVL 65
           G G  AQ   P QPA PPP   PP            +   A     D    +L   + + 
Sbjct: 66  GGGAPAQPAAPPQPAPPPPPAAPPAAPTAAPAAQTPQPPTAPKGASDAKLCALYKEAELR 125

Query: 66  YRDRAEWADIDPVPQND 82
            +  +   +  PVP ++
Sbjct: 126 LKGSSNTTECVPVPTSE 142


>gi|23503317 coiled-coil domain containing 96 [Homo sapiens]
          Length = 555

 Score = 36.2 bits (82), Expect = 0.050
 Identities = 21/54 (38%), Positives = 26/54 (48%), Gaps = 11/54 (20%)

Query: 1   MAATEGVGEAAQGGEPGQPAQPPPQPHPP----------PPQQQHKEEMAAEAG 44
           + A E  GE   G EPG+PA+P P+P  P          P      EE+ AEAG
Sbjct: 73  LTAAEAAGEEGPG-EPGRPAEPQPEPEEPAEVGAEEPAQPEPGAGPEELEAEAG 125


>gi|239757409 PREDICTED: similar to zinc finger protein 208 [Homo
           sapiens]
          Length = 1059

 Score = 35.4 bits (80), Expect = 0.085
 Identities = 19/51 (37%), Positives = 23/51 (45%), Gaps = 4/51 (7%)

Query: 16  PGQPAQPPPQPHPP----PPQQQHKEEMAAEAGEAVASPMDDGFVSLDSPS 62
           PG P QPPPQP PP    PPQ   K +    +  + +S       S  S S
Sbjct: 62  PGPPPQPPPQPPPPQYDYPPQSTFKPKAEVPSSSSSSSSSSSSSSSSSSSS 112


>gi|239746371 PREDICTED: similar to zinc finger protein 208 [Homo
           sapiens]
          Length = 1059

 Score = 35.4 bits (80), Expect = 0.085
 Identities = 19/51 (37%), Positives = 23/51 (45%), Gaps = 4/51 (7%)

Query: 16  PGQPAQPPPQPHPP----PPQQQHKEEMAAEAGEAVASPMDDGFVSLDSPS 62
           PG P QPPPQP PP    PPQ   K +    +  + +S       S  S S
Sbjct: 62  PGPPPQPPPQPPPPQYDYPPQSTFKPKAEVPSSSSSSSSSSSSSSSSSSSS 112


>gi|18426913 drebrin 1 isoform b [Homo sapiens]
          Length = 651

 Score = 35.4 bits (80), Expect = 0.085
 Identities = 18/42 (42%), Positives = 24/42 (57%), Gaps = 8/42 (19%)

Query: 20  AQPPPQPHPPPPQQQHKE--------EMAAEAGEAVASPMDD 53
           +QPPP P PPPP Q+ +E        E  A A +A A PM++
Sbjct: 364 SQPPPLPPPPPPAQETQEPSPILDSEETRAAAPQAWAGPMEE 405


>gi|18426915 drebrin 1 isoform a [Homo sapiens]
          Length = 649

 Score = 35.4 bits (80), Expect = 0.085
 Identities = 18/42 (42%), Positives = 24/42 (57%), Gaps = 8/42 (19%)

Query: 20  AQPPPQPHPPPPQQQHKE--------EMAAEAGEAVASPMDD 53
           +QPPP P PPPP Q+ +E        E  A A +A A PM++
Sbjct: 362 SQPPPLPPPPPPAQETQEPSPILDSEETRAAAPQAWAGPMEE 403


>gi|45827729 scribble isoform b [Homo sapiens]
          Length = 1630

 Score = 35.4 bits (80), Expect = 0.085
 Identities = 33/139 (23%), Positives = 59/139 (42%), Gaps = 18/139 (12%)

Query: 3    ATEGVGEAAQGGEPGQ-PAQPPPQPHPPPPQQQH-----KEEMAAEAGEAVASPMDDGFV 56
            + + V   A GG+  + P  P  Q  P PP         K+   A A    + P +D   
Sbjct: 1279 SVQRVPSGAAGGKMAESPCSPSGQQPPSPPSPDELPANVKQAYRAFAAVPTSHPPEDAPA 1338

Query: 57   S------LDSPSYVLYRDRAEWADIDP-VPQNDGPNPVVQIIYSDKFRDVYDYFRAVLQR 109
                     SP  + +R+R ++ +++  VPQ +GP   V ++ +D  R + +     LQ 
Sbjct: 1339 QPPTPGPAASPEQLSFRERQKYFELEVRVPQAEGPPKRVSLVGADDLRKMQEEEARKLQ- 1397

Query: 110  DERSERAFKLTRDAIELNA 128
                ++  ++ R+A E  A
Sbjct: 1398 ----QKRAQMLREAAEAGA 1412


>gi|45827731 scribble isoform a [Homo sapiens]
          Length = 1655

 Score = 35.4 bits (80), Expect = 0.085
 Identities = 33/139 (23%), Positives = 59/139 (42%), Gaps = 18/139 (12%)

Query: 3    ATEGVGEAAQGGEPGQ-PAQPPPQPHPPPPQQQH-----KEEMAAEAGEAVASPMDDGFV 56
            + + V   A GG+  + P  P  Q  P PP         K+   A A    + P +D   
Sbjct: 1279 SVQRVPSGAAGGKMAESPCSPSGQQPPSPPSPDELPANVKQAYRAFAAVPTSHPPEDAPA 1338

Query: 57   S------LDSPSYVLYRDRAEWADIDP-VPQNDGPNPVVQIIYSDKFRDVYDYFRAVLQR 109
                     SP  + +R+R ++ +++  VPQ +GP   V ++ +D  R + +     LQ 
Sbjct: 1339 QPPTPGPAASPEQLSFRERQKYFELEVRVPQAEGPPKRVSLVGADDLRKMQEEEARKLQ- 1397

Query: 110  DERSERAFKLTRDAIELNA 128
                ++  ++ R+A E  A
Sbjct: 1398 ----QKRAQMLREAAEAGA 1412


>gi|222144283 hypothetical protein LOC65998 [Homo sapiens]
          Length = 678

 Score = 35.0 bits (79), Expect = 0.11
 Identities = 14/26 (53%), Positives = 17/26 (65%)

Query: 13  GGEPGQPAQPPPQPHPPPPQQQHKEE 38
           G EPG  A PPP P PPPP  + +E+
Sbjct: 552 GQEPGGLALPPPPPPPPPPPPRSREQ 577


>gi|4507877 vinculin isoform VCL [Homo sapiens]
          Length = 1066

 Score = 35.0 bits (79), Expect = 0.11
 Identities = 22/74 (29%), Positives = 29/74 (39%), Gaps = 23/74 (31%)

Query: 1   MAATEGVGEAAQGGEPGQPAQPP-----------------------PQPHPPPPQQQHKE 37
           + A   V EA Q  EP  P  PP                       P P PPPP+++ +E
Sbjct: 825 LGAVAKVREAFQPQEPDFPPPPPDLEQLRLTDELAPPKPPLPEGEVPPPRPPPPEEKDEE 884

Query: 38  EMAAEAGEAVASPM 51
               +AGE +  PM
Sbjct: 885 FPEQKAGEVINQPM 898


>gi|7669550 vinculin isoform meta-VCL [Homo sapiens]
          Length = 1134

 Score = 35.0 bits (79), Expect = 0.11
 Identities = 22/74 (29%), Positives = 29/74 (39%), Gaps = 23/74 (31%)

Query: 1   MAATEGVGEAAQGGEPGQPAQPP-----------------------PQPHPPPPQQQHKE 37
           + A   V EA Q  EP  P  PP                       P P PPPP+++ +E
Sbjct: 825 LGAVAKVREAFQPQEPDFPPPPPDLEQLRLTDELAPPKPPLPEGEVPPPRPPPPEEKDEE 884

Query: 38  EMAAEAGEAVASPM 51
               +AGE +  PM
Sbjct: 885 FPEQKAGEVINQPM 898


  Database: hs.faa
    Posted date:  Aug 4, 2009  4:42 PM
  Number of letters in database: 18,247,518
  Number of sequences in database:  37,866
  
Lambda     K      H
   0.316    0.133    0.406 

Gapped
Lambda     K      H
   0.267   0.0410    0.140 


Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Hits to DB: 16,492,192
Number of Sequences: 37866
Number of extensions: 850222
Number of successful extensions: 14430
Number of sequences better than 10.0: 30
Number of HSP's better than 10.0 without gapping: 202
Number of HSP's successfully gapped in prelim test: 140
Number of HSP's that attempted gapping in prelim test: 10978
Number of HSP's gapped (non-prelim): 2590
length of query: 379
length of database: 18,247,518
effective HSP length: 104
effective length of query: 275
effective length of database: 14,309,454
effective search space: 3935099850
effective search space used: 3935099850
T: 11
A: 40
X1: 16 ( 7.3 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 41 (21.6 bits)
S2: 63 (28.9 bits)

Search results were obtained with NCBI BLAST and RefSeq entries.


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Guide to the Human Genome
Copyright © 2010 by Stewart Scherer. All rights reserved.

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