Guide to the Human Genome
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Name: VCL Sequence: fasta or formatted (1066aa) NCBI GI: 4507877
Description:

vinculin isoform VCL

Referenced in:

Cadherins and Related Proteins
Cytoskeleton
Extracellular Matrix
RNA-binding Proteins

Other entries for this name:
alt prot [1134aa] vinculin isoform meta-VCL
Composition:

amino acid map
 Amino acid        Percentage    Count  Longest homopolymer
 A alanine            12.5        133           3
 C cysteine            0.9         10           1
 D aspartate           6.0         64           2
 E glutamate           8.3         89           2
 F phenylalanine       1.4         15           1
 G glycine             5.2         55           2
 H histidine           1.0         11           1
 I isoleucine          5.3         56           2
 K lysine              7.1         76           2
 L leucine             8.8         94           3
 M methionine          3.4         36           3
 N asparagine          3.6         38           1
 P proline             5.1         54           5
 Q glutamine           5.8         62           2
 R arginine            6.2         66           2
 S serine              5.4         58           2
 T threonine           5.7         61           3
 V valine              6.7         71           2
 W tryptophan          0.8          9           1
 Y tyrosine            0.8          8           1
Comparative genomics:

Search single species RefSeq proteins at NCBI
   H. sapiens
   M. musculus
   D. rerio
   C. intestinalis
   S. purpuratus
   D. melanogaster
   C. elegans
   A. thaliana
   S. cerevisiae
   E. coli W3110
   A. pernix K1

Search summary

comparative genomics plot

   Figure data

Additional searches of
RefSeq proteins at NCBI

   All
   Eukaryotes
   Bacteria
   Archaea
   Viruses
   Primates
   Mammals
   Vertebrates

Related human proteins:
Protein          Relative score         Description

Self-match            1.000   vinculin isoform VCL 
VCL                   0.944   vinculin isoform meta-VCL 
CTNNA2                0.082   catenin, alpha 2 
CTNNA1                0.077   catenin, alpha 1 
CTNNA3                0.073   catenin, alpha 3 
CTNNA3                0.073   catenin, alpha 3 
MYH13                 0.018   myosin, heavy polypeptide 13, skeletal muscle [Homo...
MYH11                 0.016   smooth muscle myosin heavy chain 11 isoform SM1A [Ho...
MYH11                 0.016   smooth muscle myosin heavy chain 11 isoform SM1B [Ho...
MYH11                 0.016   smooth muscle myosin heavy chain 11 isoform SM2B [Ho...
MYH11                 0.016   smooth muscle myosin heavy chain 11 isoform SM2A [Ho...
PLEC1                 0.014   plectin 1 isoform 11 
PLEC1                 0.014   plectin 1 isoform 10 
PLEC1                 0.014   plectin 1 isoform 8 
PLEC1                 0.014   plectin 1 isoform 7 
PLEC1                 0.014   plectin 1 isoform 6 
PLEC1                 0.014   plectin 1 isoform 3 
PLEC1                 0.014   plectin 1 isoform 2 
PLEC1                 0.014   plectin 1 isoform 1 
MYH9                  0.014   myosin, heavy polypeptide 9, non-muscle 
MYH7B                 0.014   myosin, heavy polypeptide 7B, cardiac muscle, beta ...
CCDC158               0.013   coiled-coil domain containing 158 
MYH2                  0.011   myosin, heavy chain 2, skeletal muscle, adult [Homo...
MYH2                  0.011   myosin, heavy chain 2, skeletal muscle, adult [Homo...
FMNL1                 0.011   formin-like 1 
ANKRD24               0.011   ankyrin repeat domain 24 
MACF1                 0.011   microfilament and actin filament cross-linker protei...
MACF1                 0.011   microfilament and actin filament cross-linker protei...
MYH7                  0.011   myosin, heavy chain 7, cardiac muscle, beta 
MYH6                  0.011   myosin heavy chain 6 
Human BLASTP results (used to prepare the table)

Gene descriptions are from NCBI RefSeq. Search results were obtained with NCBI BLAST and RefSeq entries. When identical proteins are present, the self-match may not be listed first in BLASTP output. In such cases, the table above has been reordered to place it first.

See About the Figures for the scoring system used in the figure above right. The same scoring system was used in the table of BLASTP results.


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Guide to the Human Genome
Copyright © 2010 by Stewart Scherer. All rights reserved.

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