BLASTP 2.2.11 [Jun-05-2005] Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer, Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), "Gapped BLAST and PSI-BLAST: a new generation of protein database search programs", Nucleic Acids Res. 25:3389-3402. Query= gi|4502617 cyclin D2 [Homo sapiens] (289 letters) Database: hs.faa 37,866 sequences; 18,247,518 total letters Searching..................................................done Score E Sequences producing significant alignments: (bits) Value gi|4502617 cyclin D2 [Homo sapiens] 582 e-166 gi|16950655 cyclin D1 [Homo sapiens] 358 2e-99 gi|4502619 cyclin D3 isoform 2 [Homo sapiens] 351 4e-97 gi|209862835 cyclin D3 isoform 1 [Homo sapiens] 248 4e-66 gi|209915553 cyclin D3 isoform 3 [Homo sapiens] 166 2e-41 gi|4502613 cyclin A [Homo sapiens] 93 2e-19 gi|209915556 cyclin D3 isoform 4 [Homo sapiens] 89 4e-18 gi|17318565 cyclin E2 [Homo sapiens] 89 6e-18 gi|161377472 cyclin A1 isoform c [Homo sapiens] 88 8e-18 gi|161377470 cyclin A1 isoform c [Homo sapiens] 88 8e-18 gi|161377468 cyclin A1 isoform b [Homo sapiens] 88 8e-18 gi|4502611 cyclin A1 isoform a [Homo sapiens] 88 8e-18 gi|17318559 cyclin E1 isoform 1 [Homo sapiens] 80 2e-15 gi|17318561 cyclin E1 isoform 2 [Homo sapiens] 80 2e-15 gi|14327896 cyclin B1 [Homo sapiens] 70 2e-12 gi|4757930 cyclin B2 [Homo sapiens] 68 1e-11 gi|153791755 cyclin domain containing [Homo sapiens] 62 8e-10 gi|118572588 cyclin F [Homo sapiens] 62 8e-10 gi|5802992 cyclin I [Homo sapiens] 60 3e-09 gi|242247025 cyclin N-terminal domain containing 2 isoform 2 [Ho... 56 3e-08 gi|40805832 cyclin G1 [Homo sapiens] 54 1e-07 gi|4757934 cyclin G1 [Homo sapiens] 54 1e-07 gi|90669307 cyclin B3 isoform 3 [Homo sapiens] 54 2e-07 gi|197276674 cyclin J isoform 1 [Homo sapiens] 54 2e-07 gi|89886237 cyclin I family, member 2 [Homo sapiens] 50 2e-06 gi|4757936 cyclin G2 [Homo sapiens] 47 2e-05 gi|4502623 cyclin H [Homo sapiens] 44 2e-04 gi|94680985 cyclin J-like [Homo sapiens] 44 2e-04 gi|16306525 cyclin B3 isoform 1 [Homo sapiens] 44 2e-04 gi|197276676 cyclin J isoform 3 [Homo sapiens] 41 0.001 >gi|4502617 cyclin D2 [Homo sapiens] Length = 289 Score = 582 bits (1501), Expect = e-166 Identities = 289/289 (100%), Positives = 289/289 (100%) Query: 1 MELLCHEVDPVRRAVRDRNLLRDDRVLQNLLTIEERYLPQCSYFKCVQKDIQPYMRRMVA 60 MELLCHEVDPVRRAVRDRNLLRDDRVLQNLLTIEERYLPQCSYFKCVQKDIQPYMRRMVA Sbjct: 1 MELLCHEVDPVRRAVRDRNLLRDDRVLQNLLTIEERYLPQCSYFKCVQKDIQPYMRRMVA 60 Query: 61 TWMLEVCEEQKCEEEVFPLAMNYLDRFLAGVPTPKSHLQLLGAVCMFLASKLKETSPLTA 120 TWMLEVCEEQKCEEEVFPLAMNYLDRFLAGVPTPKSHLQLLGAVCMFLASKLKETSPLTA Sbjct: 61 TWMLEVCEEQKCEEEVFPLAMNYLDRFLAGVPTPKSHLQLLGAVCMFLASKLKETSPLTA 120 Query: 121 EKLCIYTDNSIKPQELLEWELVVLGKLKWNLAAVTPHDFIEHILRKLPQQREKLSLIRKH 180 EKLCIYTDNSIKPQELLEWELVVLGKLKWNLAAVTPHDFIEHILRKLPQQREKLSLIRKH Sbjct: 121 EKLCIYTDNSIKPQELLEWELVVLGKLKWNLAAVTPHDFIEHILRKLPQQREKLSLIRKH 180 Query: 181 AQTFIALCATDFKFAMYPPSMIATGSVGAAICGLQQDEEVSSLTCDALTELLAKITNTDV 240 AQTFIALCATDFKFAMYPPSMIATGSVGAAICGLQQDEEVSSLTCDALTELLAKITNTDV Sbjct: 181 AQTFIALCATDFKFAMYPPSMIATGSVGAAICGLQQDEEVSSLTCDALTELLAKITNTDV 240 Query: 241 DCLKACQEQIEAVLLNSLQQYRQDQRDGSKSEDELDQASTPTDVRDIDL 289 DCLKACQEQIEAVLLNSLQQYRQDQRDGSKSEDELDQASTPTDVRDIDL Sbjct: 241 DCLKACQEQIEAVLLNSLQQYRQDQRDGSKSEDELDQASTPTDVRDIDL 289 >gi|16950655 cyclin D1 [Homo sapiens] Length = 295 Score = 358 bits (920), Expect = 2e-99 Identities = 181/293 (61%), Positives = 224/293 (76%), Gaps = 6/293 (2%) Query: 2 ELLCHEVDPVRRAVRDRNLLRDDRVLQNLLTIEERYLPQCSYFKCVQKDIQPYMRRMVAT 61 +LLC EV+ +RRA D NLL +DRVL+ +L EE P SYFKCVQK++ P MR++VAT Sbjct: 4 QLLCCEVETIRRAYPDANLL-NDRVLRAMLKAEETCAPSVSYFKCVQKEVLPSMRKIVAT 62 Query: 62 WMLEVCEEQKCEEEVFPLAMNYLDRFLAGVPTPKSHLQLLGAVCMFLASKLKETSPLTAE 121 WMLEVCEEQKCEEEVFPLAMNYLDRFL+ P KS LQLLGA CMF+ASK+KET PLTAE Sbjct: 63 WMLEVCEEQKCEEEVFPLAMNYLDRFLSLEPVKKSRLQLLGATCMFVASKMKETIPLTAE 122 Query: 122 KLCIYTDNSIKPQELLEWELVVLGKLKWNLAAVTPHDFIEHILRKLPQQREKLSLIRKHA 181 KLCIYTDNSI+P+ELL+ EL+++ KLKWNLAA+TPHDFIEH L K+P+ E +IRKHA Sbjct: 123 KLCIYTDNSIRPEELLQMELLLVNKLKWNLAAMTPHDFIEHFLSKMPEAEENKQIIRKHA 182 Query: 182 QTFIALCATDFKFAMYPPSMIATGSVGAAICGLQQDEEVSSLTCDALTELLAKITNTDVD 241 QTF+ALCATD KF PPSM+A GSV AA+ GL + L+ LT L+++ D D Sbjct: 183 QTFVALCATDVKFISNPPSMVAAGSVVAAVQGLNLRSPNNFLSYYRLTRFLSRVIKCDPD 242 Query: 242 CLKACQEQIEAVLLNSLQQYRQDQ-----RDGSKSEDELDQASTPTDVRDIDL 289 CL+ACQEQIEA+L +SL+Q +Q+ + + E+E+D A TPTDVRD+D+ Sbjct: 243 CLRACQEQIEALLESSLRQAQQNMDPKAAEEEEEEEEEVDLACTPTDVRDVDI 295 >gi|4502619 cyclin D3 isoform 2 [Homo sapiens] Length = 292 Score = 351 bits (901), Expect = 4e-97 Identities = 183/297 (61%), Positives = 227/297 (76%), Gaps = 13/297 (4%) Query: 1 MELLCHE-VDPVRRAVRDRNLLRDDRVLQNLLTIEERYLPQCSYFKCVQKDIQPYMRRMV 59 MELLC E RA D LL D RVLQ+LL +EERY+P+ SYF+CVQ++I+P+MR+M+ Sbjct: 1 MELLCCEGTRHAPRAGPDPRLLGDQRVLQSLLRLEERYVPRASYFQCVQREIKPHMRKML 60 Query: 60 ATWMLEVCEEQKCEEEVFPLAMNYLDRFLAGVPTPKSHLQLLGAVCMFLASKLKETSPLT 119 A WMLEVCEEQ+CEEEVFPLAMNYLDR+L+ VPT K+ LQLLGAVCM LASKL+ET+PLT Sbjct: 61 AYWMLEVCEEQRCEEEVFPLAMNYLDRYLSCVPTRKAQLQLLGAVCMLLASKLRETTPLT 120 Query: 120 AEKLCIYTDNSIKPQELLEWELVVLGKLKWNLAAVTPHDFIEHILRKLPQQREKLSLIRK 179 EKLCIYTD+++ P++L +WE++VLGKLKW+LAAV HDF+ IL +L R++ +L++K Sbjct: 121 IEKLCIYTDHAVSPRQLRDWEVLVLGKLKWDLAAVIAHDFLAFILHRLSLPRDRQALVKK 180 Query: 180 HAQTFIALCATDFKFAMYPPSMIATGSVGAAICGLQQDEEVSSLTCDALTELLAKITNTD 239 HAQTF+ALCATD+ FAMYPPSMIATGS+GAA+ GL S++ D LTELLA IT T+ Sbjct: 181 HAQTFLALCATDYTFAMYPPSMIATGSIGAAVQGL----GACSMSGDELTELLAGITGTE 236 Query: 240 VDCLKACQEQIEAVLLNSLQQYRQDQRD-------GSKSEDELDQASTPTDVRDIDL 289 VDCL+ACQEQIEA L SL++ Q GS S+ Q STPTDV I L Sbjct: 237 VDCLRACQEQIEAALRESLREASQTSSSPAPKAPRGSSSQGP-SQTSTPTDVTAIHL 292 >gi|209862835 cyclin D3 isoform 1 [Homo sapiens] Length = 211 Score = 248 bits (633), Expect = 4e-66 Identities = 130/216 (60%), Positives = 162/216 (75%), Gaps = 12/216 (5%) Query: 81 MNYLDRFLAGVPTPKSHLQLLGAVCMFLASKLKETSPLTAEKLCIYTDNSIKPQELLEWE 140 MNYLDR+L+ VPT K+ LQLLGAVCM LASKL+ET+PLT EKLCIYTD+++ P++L +WE Sbjct: 1 MNYLDRYLSCVPTRKAQLQLLGAVCMLLASKLRETTPLTIEKLCIYTDHAVSPRQLRDWE 60 Query: 141 LVVLGKLKWNLAAVTPHDFIEHILRKLPQQREKLSLIRKHAQTFIALCATDFKFAMYPPS 200 ++VLGKLKW+LAAV HDF+ IL +L R++ +L++KHAQTF+ALCATD+ FAMYPPS Sbjct: 61 VLVLGKLKWDLAAVIAHDFLAFILHRLSLPRDRQALVKKHAQTFLALCATDYTFAMYPPS 120 Query: 201 MIATGSVGAAICGLQQDEEVSSLTCDALTELLAKITNTDVDCLKACQEQIEAVLLNSLQQ 260 MIATGS+GAA+ GL S++ D LTELLA IT T+VDCL+ACQEQIEA L SL++ Sbjct: 121 MIATGSIGAAVQGL----GACSMSGDELTELLAGITGTEVDCLRACQEQIEAALRESLRE 176 Query: 261 YRQDQRD-------GSKSEDELDQASTPTDVRDIDL 289 Q GS S+ Q STPTDV I L Sbjct: 177 ASQTSSSPAPKAPRGSSSQGP-SQTSTPTDVTAIHL 211 >gi|209915553 cyclin D3 isoform 3 [Homo sapiens] Length = 220 Score = 166 bits (420), Expect = 2e-41 Identities = 91/161 (56%), Positives = 113/161 (70%), Gaps = 12/161 (7%) Query: 136 LLEWELVVLGKLKWNLAAVTPHDFIEHILRKLPQQREKLSLIRKHAQTFIALCATDFKFA 195 L +WE++VLGKLKW+LAAV HDF+ IL +L R++ +L++KHAQTF+ALCATD+ FA Sbjct: 65 LEDWEVLVLGKLKWDLAAVIAHDFLAFILHRLSLPRDRQALVKKHAQTFLALCATDYTFA 124 Query: 196 MYPPSMIATGSVGAAICGLQQDEEVSSLTCDALTELLAKITNTDVDCLKACQEQIEAVLL 255 MYPPSMIATGS+GAA+ GL S++ D LTELLA IT T+VDCL+ACQEQIEA L Sbjct: 125 MYPPSMIATGSIGAAVQGL----GACSMSGDELTELLAGITGTEVDCLRACQEQIEAALR 180 Query: 256 NSLQQYRQDQRD-------GSKSEDELDQASTPTDVRDIDL 289 SL++ Q GS S+ Q STPTDV I L Sbjct: 181 ESLREASQTSSSPAPKAPRGSSSQGP-SQTSTPTDVTAIHL 220 Score = 77.4 bits (189), Expect = 1e-14 Identities = 39/66 (59%), Positives = 50/66 (75%), Gaps = 1/66 (1%) Query: 1 MELLCHE-VDPVRRAVRDRNLLRDDRVLQNLLTIEERYLPQCSYFKCVQKDIQPYMRRMV 59 MELLC E RA D LL D RVLQ+LL +EERY+P+ SYF+CVQ++I+P+MR+M+ Sbjct: 1 MELLCCEGTRHAPRAGPDPRLLGDQRVLQSLLRLEERYVPRASYFQCVQREIKPHMRKML 60 Query: 60 ATWMLE 65 A WMLE Sbjct: 61 AYWMLE 66 >gi|4502613 cyclin A [Homo sapiens] Length = 432 Score = 93.2 bits (230), Expect = 2e-19 Identities = 72/243 (29%), Positives = 120/243 (49%), Gaps = 14/243 (5%) Query: 30 LLTIEERYLPQCSYFKCVQKDIQPYMRRMVATWMLEVCEEQKCEEEVFPLAMNYLDRFLA 89 L +E + P+ Y K Q DI MR ++ W++EV EE K + E LA+NY+DRFL+ Sbjct: 186 LREMEVKCKPKVGYMK-KQPDITNSMRAILVDWLVEVGEEYKLQNETLHLAVNYIDRFLS 244 Query: 90 GVPTPKSHLQLLGAVCMFLASKLKETSPLTAEKLCIYTDNSIKPQELLEWELVVLGKLKW 149 + + LQL+G M LASK +E P + TD++ +++L E +VL L + Sbjct: 245 SMSVLRGKLQLVGTAAMLLASKFEEIYPPEVAEFVYITDDTYTKKQVLRMEHLVLKVLTF 304 Query: 150 NLAAVTPHDFI-EHILRKLPQQREKLSLIRKHAQTFIALCATDFKFAMYPPSMIATGSVG 208 +LAA T + F+ ++ L + P + SL + ++L D + Y PS+IA + Sbjct: 305 DLAAPTVNQFLTQYFLHQQPANCKVESLAMFLGE--LSLIDAD-PYLKYLPSVIAGAAFH 361 Query: 209 AAICGLQQDEEVSSLTCDALTELLAKITNTDVDCLKACQEQIEAVLLNSLQQYRQDQRDG 268 A+ ++T + E L + T ++ LK C + L + Q +Q R+ Sbjct: 362 LAL---------YTVTGQSWPESLIRKTGYTLESLKPCLMDLHQTYLKAPQHAQQSIREK 412 Query: 269 SKS 271 K+ Sbjct: 413 YKN 415 >gi|209915556 cyclin D3 isoform 4 [Homo sapiens] Length = 96 Score = 89.0 bits (219), Expect = 4e-18 Identities = 55/101 (54%), Positives = 64/101 (63%), Gaps = 12/101 (11%) Query: 196 MYPPSMIATGSVGAAICGLQQDEEVSSLTCDALTELLAKITNTDVDCLKACQEQIEAVLL 255 MYPPSMIATGS+GAA+ GL S++ D LTELLA IT T+VDCL+ACQEQIEA L Sbjct: 1 MYPPSMIATGSIGAAVQGLG----ACSMSGDELTELLAGITGTEVDCLRACQEQIEAALR 56 Query: 256 NSLQQYRQDQRD-------GSKSEDELDQASTPTDVRDIDL 289 SL++ Q GS S+ Q STPTDV I L Sbjct: 57 ESLREASQTSSSPAPKAPRGSSSQGP-SQTSTPTDVTAIHL 96 >gi|17318565 cyclin E2 [Homo sapiens] Length = 404 Score = 88.6 bits (218), Expect = 6e-18 Identities = 53/161 (32%), Positives = 86/161 (53%), Gaps = 3/161 (1%) Query: 29 NLLTIEERYLPQCSYFKCVQKDIQPYMRRMVATWMLEVCEEQKCEEEVFPLAMNYLDRF- 87 N+L E RY+ +F+ + D++P MR ++ W+LEVCE E F LA ++ DRF Sbjct: 116 NMLKKESRYVHD-KHFEVLHSDLEPQMRSILLDWLLEVCEVYTLHRETFYLAQDFFDRFM 174 Query: 88 LAGVPTPKSHLQLLGAVCMFLASKLKETSPLTAEKLCIYTDNSIKPQELLEWELVVLGKL 147 L K+ LQL+G +F+ASKL+E ++ TD + +++L EL++L L Sbjct: 175 LTQKDINKNMLQLIGITSLFIASKLEEIYAPKLQEFAYVTDGACSEEDILRMELIILKAL 234 Query: 148 KWNLAAVTPHDFIEHILR-KLPQQREKLSLIRKHAQTFIAL 187 KW L VT ++ L+ + K+ L + +TFI + Sbjct: 235 KWELCPVTIISWLNLFLQVDALKDAPKVLLPQYSQETFIQI 275 >gi|161377472 cyclin A1 isoform c [Homo sapiens] Length = 421 Score = 88.2 bits (217), Expect = 8e-18 Identities = 63/189 (33%), Positives = 98/189 (51%), Gaps = 8/189 (4%) Query: 24 DRVLQNLLTIEERYLPQCSYFKCVQKDIQPYMRRMVATWMLEVCEEQKCEEEVFPLAMNY 83 + + Q L E R+ P+ Y K Q DI MR ++ W++EV EE K E LA+N+ Sbjct: 169 EEIYQYLREAEIRHRPKAHYMK-KQPDITEGMRTILVDWLVEVGEEYKLRAETLYLAVNF 227 Query: 84 LDRFLAGVPTPKSHLQLLGAVCMFLASKLKETSPLTAEKLCIYTDNSIKPQELLEWELVV 143 LDRFL+ + + LQL+G M LASK +E P ++ TD++ ++LL+ E ++ Sbjct: 228 LDRFLSCMSVLRGKLQLVGTAAMLLASKYEEIYPPEVDEFVYITDDTYTKRQLLKMEHLL 287 Query: 144 LGKLKWNLAAVTPHDFIEHILRKLPQQREKLSLIRKHAQTFIALCATDFKFAMYPPSMIA 203 L L ++L T + F+ LR+ +L + A+ ++L D F Y PS+IA Sbjct: 288 LKVLAFDLTVPTTNQFLLQYLRRQGVCVRTENLAKYVAE--LSLLEAD-PFLKYLPSLIA 344 Query: 204 TGSVGAAIC 212 AA C Sbjct: 345 ----AAAFC 349 >gi|161377470 cyclin A1 isoform c [Homo sapiens] Length = 421 Score = 88.2 bits (217), Expect = 8e-18 Identities = 63/189 (33%), Positives = 98/189 (51%), Gaps = 8/189 (4%) Query: 24 DRVLQNLLTIEERYLPQCSYFKCVQKDIQPYMRRMVATWMLEVCEEQKCEEEVFPLAMNY 83 + + Q L E R+ P+ Y K Q DI MR ++ W++EV EE K E LA+N+ Sbjct: 169 EEIYQYLREAEIRHRPKAHYMK-KQPDITEGMRTILVDWLVEVGEEYKLRAETLYLAVNF 227 Query: 84 LDRFLAGVPTPKSHLQLLGAVCMFLASKLKETSPLTAEKLCIYTDNSIKPQELLEWELVV 143 LDRFL+ + + LQL+G M LASK +E P ++ TD++ ++LL+ E ++ Sbjct: 228 LDRFLSCMSVLRGKLQLVGTAAMLLASKYEEIYPPEVDEFVYITDDTYTKRQLLKMEHLL 287 Query: 144 LGKLKWNLAAVTPHDFIEHILRKLPQQREKLSLIRKHAQTFIALCATDFKFAMYPPSMIA 203 L L ++L T + F+ LR+ +L + A+ ++L D F Y PS+IA Sbjct: 288 LKVLAFDLTVPTTNQFLLQYLRRQGVCVRTENLAKYVAE--LSLLEAD-PFLKYLPSLIA 344 Query: 204 TGSVGAAIC 212 AA C Sbjct: 345 ----AAAFC 349 >gi|161377468 cyclin A1 isoform b [Homo sapiens] Length = 464 Score = 88.2 bits (217), Expect = 8e-18 Identities = 63/189 (33%), Positives = 98/189 (51%), Gaps = 8/189 (4%) Query: 24 DRVLQNLLTIEERYLPQCSYFKCVQKDIQPYMRRMVATWMLEVCEEQKCEEEVFPLAMNY 83 + + Q L E R+ P+ Y K Q DI MR ++ W++EV EE K E LA+N+ Sbjct: 212 EEIYQYLREAEIRHRPKAHYMK-KQPDITEGMRTILVDWLVEVGEEYKLRAETLYLAVNF 270 Query: 84 LDRFLAGVPTPKSHLQLLGAVCMFLASKLKETSPLTAEKLCIYTDNSIKPQELLEWELVV 143 LDRFL+ + + LQL+G M LASK +E P ++ TD++ ++LL+ E ++ Sbjct: 271 LDRFLSCMSVLRGKLQLVGTAAMLLASKYEEIYPPEVDEFVYITDDTYTKRQLLKMEHLL 330 Query: 144 LGKLKWNLAAVTPHDFIEHILRKLPQQREKLSLIRKHAQTFIALCATDFKFAMYPPSMIA 203 L L ++L T + F+ LR+ +L + A+ ++L D F Y PS+IA Sbjct: 331 LKVLAFDLTVPTTNQFLLQYLRRQGVCVRTENLAKYVAE--LSLLEAD-PFLKYLPSLIA 387 Query: 204 TGSVGAAIC 212 AA C Sbjct: 388 ----AAAFC 392 >gi|4502611 cyclin A1 isoform a [Homo sapiens] Length = 465 Score = 88.2 bits (217), Expect = 8e-18 Identities = 63/189 (33%), Positives = 98/189 (51%), Gaps = 8/189 (4%) Query: 24 DRVLQNLLTIEERYLPQCSYFKCVQKDIQPYMRRMVATWMLEVCEEQKCEEEVFPLAMNY 83 + + Q L E R+ P+ Y K Q DI MR ++ W++EV EE K E LA+N+ Sbjct: 213 EEIYQYLREAEIRHRPKAHYMK-KQPDITEGMRTILVDWLVEVGEEYKLRAETLYLAVNF 271 Query: 84 LDRFLAGVPTPKSHLQLLGAVCMFLASKLKETSPLTAEKLCIYTDNSIKPQELLEWELVV 143 LDRFL+ + + LQL+G M LASK +E P ++ TD++ ++LL+ E ++ Sbjct: 272 LDRFLSCMSVLRGKLQLVGTAAMLLASKYEEIYPPEVDEFVYITDDTYTKRQLLKMEHLL 331 Query: 144 LGKLKWNLAAVTPHDFIEHILRKLPQQREKLSLIRKHAQTFIALCATDFKFAMYPPSMIA 203 L L ++L T + F+ LR+ +L + A+ ++L D F Y PS+IA Sbjct: 332 LKVLAFDLTVPTTNQFLLQYLRRQGVCVRTENLAKYVAE--LSLLEAD-PFLKYLPSLIA 388 Query: 204 TGSVGAAIC 212 AA C Sbjct: 389 ----AAAFC 393 >gi|17318559 cyclin E1 isoform 1 [Homo sapiens] Length = 410 Score = 80.1 bits (196), Expect = 2e-15 Identities = 57/198 (28%), Positives = 94/198 (47%), Gaps = 21/198 (10%) Query: 24 DRVLQNLLTIEERYLPQCSYFKCVQKDIQPYMRRMVATWMLEVCEEQKCEEEVFPLAMNY 83 + V + +L E+ YL +F +QP MR ++ W++EVCE K E F LA ++ Sbjct: 114 EEVWKIMLNKEKTYLRD-QHFLEQHPLLQPKMRAILLDWLMEVCEVYKLHRETFYLAQDF 172 Query: 84 LDRFLAGVPTP-KSHLQLLGAVCMFLASKLKETSPLTAEKLCIYTDNSIKPQELLEWELV 142 DR++A K+ LQL+G +F+A+KL+E P + TD + E+L EL+ Sbjct: 173 FDRYMATQENVVKTLLQLIGISSLFIAAKLEEIYPPKLHQFAYVTDGACSGDEILTMELM 232 Query: 143 VLGKLKWNLAAVT-------------PHDFIEHILRKLPQQREKLSLIRKHAQTFIALCA 189 ++ LKW L+ +T +D E +L + PQQ I + LC Sbjct: 233 IMKALKWRLSPLTIVSWLNVYMQVAYLNDLHEVLLPQYPQQ------IFIQIAELLDLCV 286 Query: 190 TDFKFAMYPPSMIATGSV 207 D +P ++A ++ Sbjct: 287 LDVDCLEFPYGILAASAL 304 >gi|17318561 cyclin E1 isoform 2 [Homo sapiens] Length = 395 Score = 80.1 bits (196), Expect = 2e-15 Identities = 57/198 (28%), Positives = 94/198 (47%), Gaps = 21/198 (10%) Query: 24 DRVLQNLLTIEERYLPQCSYFKCVQKDIQPYMRRMVATWMLEVCEEQKCEEEVFPLAMNY 83 + V + +L E+ YL +F +QP MR ++ W++EVCE K E F LA ++ Sbjct: 99 EEVWKIMLNKEKTYLRD-QHFLEQHPLLQPKMRAILLDWLMEVCEVYKLHRETFYLAQDF 157 Query: 84 LDRFLAGVPTP-KSHLQLLGAVCMFLASKLKETSPLTAEKLCIYTDNSIKPQELLEWELV 142 DR++A K+ LQL+G +F+A+KL+E P + TD + E+L EL+ Sbjct: 158 FDRYMATQENVVKTLLQLIGISSLFIAAKLEEIYPPKLHQFAYVTDGACSGDEILTMELM 217 Query: 143 VLGKLKWNLAAVT-------------PHDFIEHILRKLPQQREKLSLIRKHAQTFIALCA 189 ++ LKW L+ +T +D E +L + PQQ I + LC Sbjct: 218 IMKALKWRLSPLTIVSWLNVYMQVAYLNDLHEVLLPQYPQQ------IFIQIAELLDLCV 271 Query: 190 TDFKFAMYPPSMIATGSV 207 D +P ++A ++ Sbjct: 272 LDVDCLEFPYGILAASAL 289 >gi|14327896 cyclin B1 [Homo sapiens] Length = 433 Score = 70.1 bits (170), Expect = 2e-12 Identities = 45/175 (25%), Positives = 82/175 (46%), Gaps = 4/175 (2%) Query: 49 KDIQPYMRRMVATWMLEVCEEQKCEEEVFPLAMNYLDRFLAGVPTPKSHLQLLGAVCMFL 108 +++ MR ++ W+++V + + +E + ++ +DRF+ PK LQL+G MF+ Sbjct: 195 REVTGNMRAILIDWLVQVQMKFRLLQETMYMTVSIIDRFMQNNCVPKKMLQLVGVTAMFI 254 Query: 109 ASKLKETSPLTAEKLCIYTDNSIKPQELLEWELVVLGKLKWNLAAVTPHDFIEHILRKLP 168 ASK +E P TDN+ ++ + E+ +L L + L P F+ + Sbjct: 255 ASKYEEMYPPEIGDFAFVTDNTYTKHQIRQMEMKILRALNFGLGRPLPLHFLRRASKIGE 314 Query: 169 QQREKLSLIRKHAQTFIALCATDFKFAMYPPSMIATGSVGAAICGLQQDEEVSSL 223 E+ +L A+ + L D+ +PPS IA G+ A+ L E +L Sbjct: 315 VDVEQHTL----AKYLMELTMLDYDMVHFPPSQIAAGAFCLALKILDNGEWTPTL 365 >gi|4757930 cyclin B2 [Homo sapiens] Length = 398 Score = 67.8 bits (164), Expect = 1e-11 Identities = 42/158 (26%), Positives = 74/158 (46%), Gaps = 4/158 (2%) Query: 49 KDIQPYMRRMVATWMLEVCEEQKCEEEVFPLAMNYLDRFLAGVPTPKSHLQLLGAVCMFL 108 +DI MR ++ W+++V + + +E + + +DRFL P + LQL+G + L Sbjct: 159 RDINGRMRAILVDWLVQVHSKFRLLQETLYMCVGIMDRFLQVQPVSRKKLQLVGITALLL 218 Query: 109 ASKLKETSPLTAEKLCIYTDNSIKPQELLEWELVVLGKLKWNLAAVTPHDFIEHILRKLP 168 ASK +E E TDN+ ++ E E ++L +LK+ L P F+ + Sbjct: 219 ASKYEEMFSPNIEDFVYITDNAYTSSQIREMETLILKELKFELGRPLPLHFLRRASKAGE 278 Query: 169 QQREKLSLIRKHAQTFIALCATDFKFAMYPPSMIATGS 206 E+ +L A+ + L D+ Y PS +A + Sbjct: 279 VDVEQHTL----AKYLMELTLIDYDMVHYHPSKVAAAA 312 >gi|153791755 cyclin domain containing [Homo sapiens] Length = 350 Score = 61.6 bits (148), Expect = 8e-10 Identities = 46/160 (28%), Positives = 67/160 (41%), Gaps = 4/160 (2%) Query: 48 QKDIQPYMRRMVATWMLEVCEEQKCEEEVFPLAMNYLDRFLAGVPTPKSHLQLLGAVCMF 107 Q + R + +W++ V + E L +N LDRFL P QLLG + Sbjct: 125 QPQVTAESRCKLLSWLIPVHRQFGLSFESLCLTVNTLDRFLTTTPVAADCFQLLGVTSLL 184 Query: 108 LASKLKETSPLTAEKLCIYTDNSIKPQELLEWELVVLGKLKWNLAAVTPHDFIEHI--LR 165 +A K E P ++L + Q+L E +VL KL + L A T F+EH R Sbjct: 185 IACKQVEVHPPRVKQLLALCCGAFSRQQLCNLECIVLHKLHFTLGAPTISFFLEHFTHAR 244 Query: 166 KLPQQREKLSLIRKH--AQTFIALCATDFKFAMYPPSMIA 203 Q E + A+ L D+ F Y PS++A Sbjct: 245 VEAGQAEASEALEAQALARGVAELSLADYAFTSYSPSLLA 284 >gi|118572588 cyclin F [Homo sapiens] Length = 786 Score = 61.6 bits (148), Expect = 8e-10 Identities = 54/235 (22%), Positives = 105/235 (44%), Gaps = 11/235 (4%) Query: 47 VQKDIQPYMRRMVATWMLEVCEEQKCEEEVFPLAMNYLDRFLAGVPTPKSHLQLLGAVCM 106 VQK + MR ++ W++EV + L + +DR+L P+ LQLLG CM Sbjct: 301 VQKGLNDTMRYILIDWLVEVATMKDFTSLCLHLTVECVDRYLRRRLVPRYRLQLLGIACM 360 Query: 107 FLASKLKETSPLTAEKLCIYTDNSIKPQELLEWELVVLGKLKWNLAAVTPHDFIEHILRK 166 + ++ LT + TDN+ K ++L+ ++ L+ + T D+ E +L Sbjct: 361 VICTRFISKEILTIREAVWLTDNTYKYEDLVRMMGEIVSALEGKIRVPTVVDYKEVLLTL 420 Query: 167 LPQQREKLSLIRKHAQTFIA-LCATDFKFAMYPPSMIATGSVGAAICGLQQDE----EVS 221 +P + L +H +F+ L + Y P+ +A ++ A Q + ++ Sbjct: 421 VP-----VELRTQHLCSFLCELSLLHTSLSAYAPARLAAAALLLARLTHGQTQPWTTQLW 475 Query: 222 SLTCDALTELLAKITNTDVDCL-KACQEQIEAVLLNSLQQYRQDQRDGSKSEDEL 275 LT + +L+ + + C + V L +++Q +D+R G S++E+ Sbjct: 476 DLTGFSYEDLIPCVLSLHKKCFHDDAPKDYRQVSLTAVKQRFEDKRYGEISQEEV 530 >gi|5802992 cyclin I [Homo sapiens] Length = 377 Score = 59.7 bits (143), Expect = 3e-09 Identities = 37/121 (30%), Positives = 56/121 (46%), Gaps = 3/121 (2%) Query: 49 KDIQPYMRRMVATWMLEVCEEQKCEEEVFPLAMNYLDRFLAGVPTPKSHLQLLGAVCMFL 108 +++ P R V W+ ++ + E F LA + LDRFLA V +L + C FL Sbjct: 38 QNVSPSQRDEVIQWLAKLKYQFNLYPETFALASSLLDRFLATVKAHPKYLSCIAISCFFL 97 Query: 109 ASKLKETSPLTAEKLCIYTDN--SIKPQELLEWELVVLGKLKWNLAAVTPHDFIEHILRK 166 A+K E + D+ E+L E ++L KL W+L TP DF+ HI Sbjct: 98 AAKTVEEDERIPVLKVLARDSFCGCSSSEILRMERIILDKLNWDLHTATPLDFL-HIFHA 156 Query: 167 L 167 + Sbjct: 157 I 157 >gi|242247025 cyclin N-terminal domain containing 2 isoform 2 [Homo sapiens] Length = 307 Score = 56.2 bits (134), Expect = 3e-08 Identities = 32/107 (29%), Positives = 55/107 (51%) Query: 45 KCVQKDIQPYMRRMVATWMLEVCEEQKCEEEVFPLAMNYLDRFLAGVPTPKSHLQLLGAV 104 + + + + P MR +V W+++V E + LA++ LD +L+ LQLLG Sbjct: 97 RALPRAVTPEMRALVVDWLVQVHEYLGLAGDTLYLAVHLLDSYLSAGRVRLHRLQLLGVA 156 Query: 105 CMFLASKLKETSPLTAEKLCIYTDNSIKPQELLEWELVVLGKLKWNL 151 C+F+A K++E LC+ + +S ELL E +L +L + L Sbjct: 157 CLFVACKMEECVLPEPAFLCLLSADSFSRAELLRAERRILSRLDFRL 203 >gi|40805832 cyclin G1 [Homo sapiens] Length = 295 Score = 54.3 bits (129), Expect = 1e-07 Identities = 44/161 (27%), Positives = 72/161 (44%), Gaps = 11/161 (6%) Query: 73 EEEVFPLAMNYLDRFLAGVPTPKSHLQLLGAVCMFLASKLKETS---PLTAEKLCIYTDN 129 + E F LA+N LDRFL+ + HL +G C +LA K E PL + + I + Sbjct: 69 DTETFSLAVNLLDRFLSKMKVQPKHLGCVGLSCFYLAVKSIEEERNVPLATDLIRI-SQY 127 Query: 130 SIKPQELLEWELVVLGKLKWNLAAVTPHDFIE----HILRKLP-QQREKLSLIRKHAQTF 184 +L+ E +VL K+ W + A T F++ + LP ++R ++ R AQ Sbjct: 128 RFTVSDLMRMEKIVLEKVCWKVKATTAFQFLQLYYSLLQENLPLERRNSINFERLEAQ-- 185 Query: 185 IALCATDFKFAMYPPSMIATGSVGAAICGLQQDEEVSSLTC 225 + C F+ PS++A + I + E + C Sbjct: 186 LKACHCRIIFSKAKPSVLALSIIALEIQAQKCVELTEGIEC 226 >gi|4757934 cyclin G1 [Homo sapiens] Length = 295 Score = 54.3 bits (129), Expect = 1e-07 Identities = 44/161 (27%), Positives = 72/161 (44%), Gaps = 11/161 (6%) Query: 73 EEEVFPLAMNYLDRFLAGVPTPKSHLQLLGAVCMFLASKLKETS---PLTAEKLCIYTDN 129 + E F LA+N LDRFL+ + HL +G C +LA K E PL + + I + Sbjct: 69 DTETFSLAVNLLDRFLSKMKVQPKHLGCVGLSCFYLAVKSIEEERNVPLATDLIRI-SQY 127 Query: 130 SIKPQELLEWELVVLGKLKWNLAAVTPHDFIE----HILRKLP-QQREKLSLIRKHAQTF 184 +L+ E +VL K+ W + A T F++ + LP ++R ++ R AQ Sbjct: 128 RFTVSDLMRMEKIVLEKVCWKVKATTAFQFLQLYYSLLQENLPLERRNSINFERLEAQ-- 185 Query: 185 IALCATDFKFAMYPPSMIATGSVGAAICGLQQDEEVSSLTC 225 + C F+ PS++A + I + E + C Sbjct: 186 LKACHCRIIFSKAKPSVLALSIIALEIQAQKCVELTEGIEC 226 >gi|90669307 cyclin B3 isoform 3 [Homo sapiens] Length = 1395 Score = 53.9 bits (128), Expect = 2e-07 Identities = 34/131 (25%), Positives = 61/131 (46%) Query: 48 QKDIQPYMRRMVATWMLEVCEEQKCEEEVFPLAMNYLDRFLAGVPTPKSHLQLLGAVCMF 107 Q +I MR ++ W++EV + E LA+ +D +L K LQLLGA Sbjct: 1153 QIEITSDMRAILVDWLVEVQVSFEMTHETLYLAVKLVDLYLMKAVCKKDKLQLLGATAFM 1212 Query: 108 LASKLKETSPLTAEKLCIYTDNSIKPQELLEWELVVLGKLKWNLAAVTPHDFIEHILRKL 167 +A+K +E + + D++ + E+L E+ +L LK ++ + F+ R + Sbjct: 1213 IAAKFEEHNSPRVDDFVYICDDNYQRSEVLSMEINILNVLKCDINIPIAYHFLRRYARCI 1272 Query: 168 PQQREKLSLIR 178 + L+L R Sbjct: 1273 HTNMKTLTLSR 1283 >gi|197276674 cyclin J isoform 1 [Homo sapiens] Length = 383 Score = 53.9 bits (128), Expect = 2e-07 Identities = 46/151 (30%), Positives = 68/151 (45%), Gaps = 19/151 (12%) Query: 79 LAMNYLDRFLAGVPTPKSHLQLLGAVCMFLASKL--KETSPLTAEKL----CIYTDNSI- 131 LA+ LD F+ L L+ C+ LASK KE S E+L C+ N + Sbjct: 63 LAVYLLDLFMDRYDISIQQLHLVALSCLLLASKFEEKEDSVPKLEQLNSLGCMTNMNLVL 122 Query: 132 KPQELLEWELVVLGKLKWNLAAVTPHDFIEHILRKLPQQR-----------EKLSL-IRK 179 Q LL EL++L +WNL T FIE+ L + + EK L + K Sbjct: 123 TKQNLLHMELLLLETFQWNLCLPTAAHFIEYYLSEAVHETDLHDGWPMICLEKTKLYMAK 182 Query: 180 HAQTFIALCATDFKFAMYPPSMIATGSVGAA 210 +A F+ + D+ F Y PS++A V ++ Sbjct: 183 YADYFLEVSLQDYAFLNYAPSLVAAACVASS 213 >gi|89886237 cyclin I family, member 2 [Homo sapiens] Length = 369 Score = 50.4 bits (119), Expect = 2e-06 Identities = 50/214 (23%), Positives = 83/214 (38%), Gaps = 23/214 (10%) Query: 59 VATWMLEVCEEQKCEEEVFPLAMNYLDRFLAGVPTPKSHLQLLGAVCMFLASKLKETSPL 118 V W+L + + F LA+ R L V + +L + LA+K+ E Sbjct: 153 VVLWLLRLQNTFYFSQSTFNLALTIFGRLLISVKVKEKYLHCATITSLRLAAKVNEEEEF 212 Query: 119 TAE--KLCIYTDNSIKPQELLEWELVVLGKLKWNLAAVTPHDFI-----------EHILR 165 + + + P ELL EL +L +L W+L TP DF+ H+L Sbjct: 213 IPQVKDFTKHYGSDYSPNELLRMELAILDRLHWDLYIGTPLDFLTIFHALVVLSWPHVLE 272 Query: 166 KLPQQREKLSLIRKHAQTFIALCATDFKFAMYPPSMIATGSVGAAICGLQQDEEVSSLTC 225 LPQ+ L + Q + C + + GS A + + E + C Sbjct: 273 LLPQRNPSLHVASLTRQ--LQHCMAGHQLLQF------KGSTLALVIITLELERLMPGWC 324 Query: 226 DALTELLAKITNTDVDCLKACQEQIEAVLLNSLQ 259 +++LL K D+ +C +++ L SLQ Sbjct: 325 APISDLLKKAQVGDMQ--YSCCKELVMQQLRSLQ 356 >gi|4757936 cyclin G2 [Homo sapiens] Length = 344 Score = 47.0 bits (110), Expect = 2e-05 Identities = 51/178 (28%), Positives = 82/178 (46%), Gaps = 25/178 (14%) Query: 75 EVFPLAMNYLDRFLAGVPTPKSHLQLLGAVCMFLASKLKETS---PLTAEKLCIYTDNSI 131 E F LA+N LDRFLA + HL +G LA+++ E P T + + I + Sbjct: 75 ETFVLAVNILDRFLALMKVKPKHLSCIGVCSFLLAARIVEEDCNIPSTHDVIRI-SQCKC 133 Query: 132 KPQELLEWELVVLGKLKWNLAAVTPHDFIE----HILRKLPQQREKLSLIRKHAQTFIAL 187 ++ E ++ KL + L A T +F+ IL +++E LSL + AQ + Sbjct: 134 TASDIKRMEKIISEKLHYELEATTALNFLHLYHTIILCHTSERKEILSLDKLEAQ--LKA 191 Query: 188 CATDFKFAMYPPSMIATGSVGAAICGLQQDEEVSSLTCDALTELL------AKITNTD 239 C F+ PS++ A+C L + EV +L L E+L +KI +T+ Sbjct: 192 CNCRLIFSKAKPSVL-------ALCLL--NLEVETLKSVELLEILLLVKKHSKINDTE 240 >gi|4502623 cyclin H [Homo sapiens] Length = 323 Score = 43.9 bits (102), Expect = 2e-04 Identities = 45/179 (25%), Positives = 74/179 (41%), Gaps = 29/179 (16%) Query: 63 MLEVCEEQK--CEEEVFPLAMNYLDRFLAGVPTPKSHLQLLGAVCMFLASKLKE------ 114 +LE C K V A Y RF + H +++ C FLA K+ E Sbjct: 64 LLEFCSVFKPAMPRSVVGTACMYFKRFYLNNSVMEYHPRIIMLTCAFLACKVDEFNVSSP 123 Query: 115 -------TSPLTAEKLCIYTDNSIKPQELLEWELVVLGKLKWNLAAVTPHDFIEHILRKL 167 SPL EK +++LE+EL+++ +L ++L P+ E L L Sbjct: 124 QFVGNLRESPLGQEKAL---------EQILEYELLLIQQLNFHLIVHNPYRPFEGFLIDL 174 Query: 168 PQQR---EKLSLIRKHAQTFIALCATDFKFAMYPPSMIATGSV--GAAICGLQQDEEVS 221 + E ++RK A F+ A + +Y PS IA ++ A+ G+ + +S Sbjct: 175 KTRYPILENPEILRKTADDFLNRIALTDAYLLYTPSQIALTAILSSASRAGITMESYLS 233 >gi|94680985 cyclin J-like [Homo sapiens] Length = 435 Score = 43.9 bits (102), Expect = 2e-04 Identities = 36/143 (25%), Positives = 62/143 (43%), Gaps = 21/143 (14%) Query: 130 SIKPQELLEWELVVLGKLKWNLAAVTPHDFIEHILRKLPQQ-------------REKLSL 176 ++ +ELL EL++L WNL TP F+++ L Q R+ Sbjct: 169 TLTKKELLSTELLLLEAFSWNLCLPTPAHFLDYYLLASVSQKDHHCHTWPTTCPRKTKEC 228 Query: 177 IRKHAQTFIALCATDFKFAMYPPSMIATGSVGAAICGLQQDEEVSSLTCDALTELLAKIT 236 ++++A F+ + D F + PS++A VGA+ LQ T L +I+ Sbjct: 229 LKEYAHYFLEVTLQDHIFYKFQPSVVAAACVGASRICLQ--------LSPYWTRDLQRIS 280 Query: 237 NTDVDCLKACQEQIEAVLLNSLQ 259 + ++ L C E + V N L+ Sbjct: 281 SYSLEHLSTCIEILLVVYDNVLK 303 >gi|16306525 cyclin B3 isoform 1 [Homo sapiens] Length = 291 Score = 43.5 bits (101), Expect = 2e-04 Identities = 27/104 (25%), Positives = 48/104 (46%) Query: 75 EVFPLAMNYLDRFLAGVPTPKSHLQLLGAVCMFLASKLKETSPLTAEKLCIYTDNSIKPQ 134 E LA+ +D +L K LQLLGA +A+K +E + + D++ + Sbjct: 76 ETLYLAVKLVDLYLMKAVCKKDKLQLLGATAFMIAAKFEEHNSPRVDDFVYICDDNYQRS 135 Query: 135 ELLEWELVVLGKLKWNLAAVTPHDFIEHILRKLPQQREKLSLIR 178 E+L E+ +L LK ++ + F+ R + + L+L R Sbjct: 136 EVLSMEINILNVLKCDINIPIAYHFLRRYARCIHTNMKTLTLSR 179 >gi|197276676 cyclin J isoform 3 [Homo sapiens] Length = 371 Score = 41.2 bits (95), Expect = 0.001 Identities = 33/93 (35%), Positives = 44/93 (47%), Gaps = 7/93 (7%) Query: 79 LAMNYLDRFLAGVPTPKSHLQLLGAVCMFLASKL--KETSPLTAEKL----CIYTDNSI- 131 LA+ LD F+ L L+ C+ LASK KE S E+L C+ N + Sbjct: 63 LAVYLLDLFMDRYDISIQQLHLVALSCLLLASKFEEKEDSVPKLEQLNSLGCMTNMNLVL 122 Query: 132 KPQELLEWELVVLGKLKWNLAAVTPHDFIEHIL 164 Q LL EL++L +WNL T FIE+ L Sbjct: 123 TKQNLLHMELLLLETFQWNLCLPTAAHFIEYYL 155 Database: hs.faa Posted date: Aug 4, 2009 4:42 PM Number of letters in database: 18,247,518 Number of sequences in database: 37,866 Lambda K H 0.321 0.135 0.401 Gapped Lambda K H 0.267 0.0410 0.140 Matrix: BLOSUM62 Gap Penalties: Existence: 11, Extension: 1 Number of Hits to DB: 11,143,764 Number of Sequences: 37866 Number of extensions: 473495 Number of successful extensions: 1137 Number of sequences better than 10.0: 30 Number of HSP's better than 10.0 without gapping: 32 Number of HSP's successfully gapped in prelim test: 9 Number of HSP's that attempted gapping in prelim test: 1086 Number of HSP's gapped (non-prelim): 42 length of query: 289 length of database: 18,247,518 effective HSP length: 101 effective length of query: 188 effective length of database: 14,423,052 effective search space: 2711533776 effective search space used: 2711533776 T: 11 A: 40 X1: 16 ( 7.4 bits) X2: 38 (14.6 bits) X3: 64 (24.7 bits) S1: 41 (21.9 bits) S2: 61 (28.1 bits)
Search results were obtained with NCBI BLAST and RefSeq entries.
Guide to the Human Genome
Copyright © 2010 by Stewart Scherer. All rights reserved.