Guide to the Human Genome
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Search of human proteins with 4502519

BLASTP 2.2.11 [Jun-05-2005]


Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer, 
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), 
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs",  Nucleic Acids Res. 25:3389-3402.

Query= gi|4502519 carbonic anhydrase IV precursor [Homo sapiens]
         (312 letters)

Database: hs.faa 
           37,866 sequences; 18,247,518 total letters

Searching..................................................done

                                                                 Score    E
Sequences producing significant alignments:                      (bits) Value

gi|4502519 carbonic anhydrase IV precursor [Homo sapiens]             636   0.0  
gi|45935383 carbonic anhydrase XII isoform 2 precursor [Homo sap...   146   3e-35
gi|6912284 carbonic anhydrase XIV precursor [Homo sapiens]            144   1e-34
gi|4502515 carbonic anhydrase XII isoform 1 precursor [Homo sapi...   141   6e-34
gi|70167127 carbonic anhydrase VI precursor [Homo sapiens]            135   4e-32
gi|4885101 carbonic anhydrase VII isoform 1 [Homo sapiens]            130   1e-30
gi|194097398 protein tyrosine phosphatase, receptor type, G prec...   126   2e-29
gi|4557395 carbonic anhydrase II [Homo sapiens]                       123   2e-28
gi|38348436 carbonic anhydrase XIII [Homo sapiens]                    121   9e-28
gi|4885099 carbonic anhydrase III [Homo sapiens]                      120   1e-27
gi|6005723 carbonic anhydrase VB, mitochondrial precursor [Homo ...   116   3e-26
gi|62240989 carbonic anhydrase VII isoform 2 [Homo sapiens]           112   4e-25
gi|91208428 protein tyrosine phosphatase, receptor-type, zeta1 p...   111   7e-25
gi|169636420 carbonic anhydrase IX precursor [Homo sapiens]           111   9e-25
gi|22027500 carbonic anhydrase VIII [Homo sapiens]                    109   3e-24
gi|4502521 carbonic anhydrase VA, mitochondrial precursor [Homo ...   108   6e-24
gi|192447434 carbonic anhydrase I [Homo sapiens]                      106   2e-23
gi|192447432 carbonic anhydrase I [Homo sapiens]                      106   2e-23
gi|192447430 carbonic anhydrase I [Homo sapiens]                      106   2e-23
gi|4502517 carbonic anhydrase I [Homo sapiens]                        106   2e-23
gi|130979954 carbonic anhydrase X [Homo sapiens]                       96   3e-20
gi|130979679 carbonic anhydrase X [Homo sapiens]                       96   3e-20
gi|9910366 carbonic anhydrase X [Homo sapiens]                         96   3e-20
gi|9951923 carbonic anhydrase XI precursor [Homo sapiens]              75   1e-13
gi|239757628 PREDICTED: similar to hCG1646661 [Homo sapiens]           47   2e-05
gi|239752124 PREDICTED: similar to hCG1646661 [Homo sapiens]           47   2e-05
gi|239746634 PREDICTED: similar to hCG1646661 [Homo sapiens]           47   2e-05
gi|239746647 PREDICTED: similar to hCG1646661 [Homo sapiens]           47   3e-05
gi|239757641 PREDICTED: similar to hCG1646661 [Homo sapiens]           45   6e-05
gi|50233787 nuclear protein in testis [Homo sapiens]                   30   2.8  

>gi|4502519 carbonic anhydrase IV precursor [Homo sapiens]
          Length = 312

 Score =  636 bits (1641), Expect = 0.0
 Identities = 312/312 (100%), Positives = 312/312 (100%)

Query: 1   MRMLLALLALSAARPSASAESHWCYEVQAESSNYPCLVPVKWGGNCQKDRQSPINIVTTK 60
           MRMLLALLALSAARPSASAESHWCYEVQAESSNYPCLVPVKWGGNCQKDRQSPINIVTTK
Sbjct: 1   MRMLLALLALSAARPSASAESHWCYEVQAESSNYPCLVPVKWGGNCQKDRQSPINIVTTK 60

Query: 61  AKVDKKLGRFFFSGYDKKQTWTVQNNGHSVMMLLENKASISGGGLPAPYQAKQLHLHWSD 120
           AKVDKKLGRFFFSGYDKKQTWTVQNNGHSVMMLLENKASISGGGLPAPYQAKQLHLHWSD
Sbjct: 61  AKVDKKLGRFFFSGYDKKQTWTVQNNGHSVMMLLENKASISGGGLPAPYQAKQLHLHWSD 120

Query: 121 LPYKGSEHSLDGEHFAMEMHIVHEKEKGTSRNVKEAQDPEDEIAVLAFLVEAGTQVNEGF 180
           LPYKGSEHSLDGEHFAMEMHIVHEKEKGTSRNVKEAQDPEDEIAVLAFLVEAGTQVNEGF
Sbjct: 121 LPYKGSEHSLDGEHFAMEMHIVHEKEKGTSRNVKEAQDPEDEIAVLAFLVEAGTQVNEGF 180

Query: 181 QPLVEALSNIPKPEMSTTMAESSLLDLLPKEEKLRHYFRYLGSLTTPTCDEKVVWTVFRE 240
           QPLVEALSNIPKPEMSTTMAESSLLDLLPKEEKLRHYFRYLGSLTTPTCDEKVVWTVFRE
Sbjct: 181 QPLVEALSNIPKPEMSTTMAESSLLDLLPKEEKLRHYFRYLGSLTTPTCDEKVVWTVFRE 240

Query: 241 PIQLHREQILAFSQKLYYDKEQTVSMKDNVRPLQQLGQRTVIKSGAPGRPLPWALPALLG 300
           PIQLHREQILAFSQKLYYDKEQTVSMKDNVRPLQQLGQRTVIKSGAPGRPLPWALPALLG
Sbjct: 241 PIQLHREQILAFSQKLYYDKEQTVSMKDNVRPLQQLGQRTVIKSGAPGRPLPWALPALLG 300

Query: 301 PMLACLLAGFLR 312
           PMLACLLAGFLR
Sbjct: 301 PMLACLLAGFLR 312


>gi|45935383 carbonic anhydrase XII isoform 2 precursor [Homo
           sapiens]
          Length = 343

 Score =  146 bits (368), Expect = 3e-35
 Identities = 103/316 (32%), Positives = 161/316 (50%), Gaps = 19/316 (6%)

Query: 3   MLLALLALSAARPSASAESHWCYEVQAESSNYPCLVPVKWGGNCQKDRQSPINIVTTKAK 62
           +LL +L    + P+    S W Y      +++    P     +C    QSPI++ +   +
Sbjct: 12  LLLVILKEQPSSPAPVNGSKWTYFGPDGENSWSKKYP-----SCGGLLQSPIDLHSDILQ 66

Query: 63  VDKKLGRFFFSGYD--KKQTWTVQNNGHSVMMLLENKASISGGGLPAPYQAKQLHLHWSD 120
            D  L    F GY+    + + + NNGHSV + L +   I G  L + Y A QLHLHW +
Sbjct: 67  YDASLTPLEFQGYNLSANKQFLLTNNGHSVKLNLPSDMHIQG--LQSRYSATQLHLHWGN 124

Query: 121 L--PYKGSEHSLDGEHFAMEMHIVHEKEKGTSRNVKEAQDPEDEIAVLAFLVEAGTQVNE 178
              P+ GSEH++ G+HFA E+HIVH        +   A +  + +AVLA L+E G+  N 
Sbjct: 125 PNDPH-GSEHTVSGQHFAAELHIVHYNSD-LYPDASTASNKSEGLAVLAVLIEMGS-FNP 181

Query: 179 GFQPLVEALSNIPKPEMSTTMAESSLLDLLPKEEKLRHYFRYLGSLTTPTCDEKVVWTVF 238
            +  +   L ++        +   ++ +LLP  E+   Y+RY GSLTTP C+  V+WTVF
Sbjct: 182 SYDKIFSHLQHVKYKGQEAFVPGFNIEELLP--ERTAEYYRYRGSLTTPPCNPTVLWTVF 239

Query: 239 REPIQLHREQILAFSQKLY---YDKEQTVSMKDNVRPLQQLGQRTVIKSGAPGRPLPWAL 295
           R P+Q+ +EQ+LA    LY    D      M +N R +Q+  +R V  S + G  L  AL
Sbjct: 240 RNPVQISQEQLLALETALYCTHMDDPSPREMINNFRQVQKFDERLVYTSFSQGIILSLAL 299

Query: 296 PALLGPMLACLLAGFL 311
             +LG  +  +++ +L
Sbjct: 300 AGILGICIVVVVSIWL 315


>gi|6912284 carbonic anhydrase XIV precursor [Homo sapiens]
          Length = 337

 Score =  144 bits (362), Expect = 1e-34
 Identities = 95/273 (34%), Positives = 136/273 (49%), Gaps = 14/273 (5%)

Query: 16  SASAESHWCYEVQAESSNYPCLVPVKWGGNCQKDRQSPINIVTTKAKVDKKLGRFFFSGY 75
           +A    HW YE      ++P   P      C  + QSPI+I T     D  L      GY
Sbjct: 15  AADGGQHWTYEGPHGQDHWPASYP-----ECGNNAQSPIDIQTDSVTFDPDLPALQPHGY 69

Query: 76  DKKQT--WTVQNNGHSVMMLLENKASISGGGLPAPYQAKQLHLHWSDLPYKG-SEHSLDG 132
           D+  T    + NNGH+V + L +   +  GGLP  Y A QLHLHW      G SEH ++ 
Sbjct: 70  DQPGTEPLDLHNNGHTVQLSLPSTLYL--GGLPRKYVAAQLHLHWGQKGSPGGSEHQINS 127

Query: 133 EHFAMEMHIVHEKEKGTSRNVKEAQDPEDEIAVLAFLVEAGTQVNEGFQPLVEALSNIPK 192
           E    E+HIVH  +  +  ++ EA +    +AVL  L+E G   N  ++ ++  L  +  
Sbjct: 128 EATFAELHIVHY-DSDSYDSLSEAAERPQGLAVLGILIEVGETKNIAYEHILSHLHEVRH 186

Query: 193 PEMSTTMAESSLLDLLPKEEKLRHYFRYLGSLTTPTCDEKVVWTVFREPIQLHREQILAF 252
            +  T++   +L +LLPK+  L  YFRY GSLTTP C + V+WTVF    Q+  EQ+   
Sbjct: 187 KDQKTSVPPFNLRELLPKQ--LGQYFRYNGSLTTPPCYQSVLWTVFYRRSQISMEQLEKL 244

Query: 253 SQKLY-YDKEQTVSMKDNVRPLQQLGQRTVIKS 284
              L+  ++E +  +  N R LQ L QR V  S
Sbjct: 245 QGTLFSTEEEPSKLLVQNYRALQPLNQRMVFAS 277


>gi|4502515 carbonic anhydrase XII isoform 1 precursor [Homo
           sapiens]
          Length = 354

 Score =  141 bits (356), Expect = 6e-34
 Identities = 104/316 (32%), Positives = 160/316 (50%), Gaps = 20/316 (6%)

Query: 3   MLLALLALSAARPSASAESHWCYEVQAESSNYPCLVPVKWGGNCQKDRQSPINIVTTKAK 62
           +LL +L    + P+    S W Y      +++    P     +C    QSPI++ +   +
Sbjct: 12  LLLVILKEQPSSPAPVNGSKWTYFGPDGENSWSKKYP-----SCGGLLQSPIDLHSDILQ 66

Query: 63  VDKKLGRFFFSGYD--KKQTWTVQNNGHSVMMLLENKASISGGGLPAPYQAKQLHLHWSD 120
            D  L    F GY+    + + + NNGHSV + L +   I G  L + Y A QLHLHW +
Sbjct: 67  YDASLTPLEFQGYNLSANKQFLLTNNGHSVKLNLPSDMHIQG--LQSRYSATQLHLHWGN 124

Query: 121 L--PYKGSEHSLDGEHFAMEMHIVHEKEKGTSRNVKEAQDPEDEIAVLAFLVEAGTQVNE 178
              P+ GSEH++ G+HFA E+HIVH        +   A +  + +AVLA L+E G+  N 
Sbjct: 125 PNDPH-GSEHTVSGQHFAAELHIVHYNSD-LYPDASTASNKSEGLAVLAVLIEMGS-FNP 181

Query: 179 GFQPLVEALSNIPKPEMSTTMAESSLLDLLPKEEKLRHYFRYLGSLTTPTCDEKVVWTVF 238
            +  +   L ++        +   ++ +LLP  E+   Y+RY GSLTTP C+  V+WTVF
Sbjct: 182 SYDKIFSHLQHVKYKGQEAFVPGFNIEELLP--ERTAEYYRYRGSLTTPPCNPTVLWTVF 239

Query: 239 REPIQLHREQILAFSQKLY---YDKEQTVSMKDNVRPLQQLGQRTVIKSGAPGRPLPWAL 295
           R P+Q+ +EQ+LA    LY    D      M +N R +Q+  +R V  S +  + +  A 
Sbjct: 240 RNPVQISQEQLLALETALYCTHMDDPSPREMINNFRQVQKFDERLVYTSFSQVQ-VCTAA 298

Query: 296 PALLGPMLACLLAGFL 311
              LG +L+  LAG L
Sbjct: 299 GLSLGIILSLALAGIL 314


>gi|70167127 carbonic anhydrase VI precursor [Homo sapiens]
          Length = 308

 Score =  135 bits (341), Expect = 4e-32
 Identities = 98/296 (33%), Positives = 151/296 (51%), Gaps = 22/296 (7%)

Query: 1   MRMLLALLALSAARPSASAESHWCYEVQA-ESSNYPCLVPVKWGGNCQKDRQSPINIVTT 59
           MR L+ LL+L      A   S W Y   A + +++P   P      C   RQSPIN+  T
Sbjct: 1   MRALVLLLSLFLLGGQAQHVSDWTYSEGALDEAHWPQHYPA-----CGGQRQSPINLQRT 55

Query: 60  KAKVDKKLGRFFFSGYDKKQ-TWTVQNNGHSVMMLLEN--KASISGGGLPAPYQAKQLHL 116
           K + +  L     +GY+ +   + + NNGH+V + L +  + +++ G +   Y A+Q+H 
Sbjct: 56  KVRYNPSLKGLNMTGYETQAGEFPMVNNGHTVQISLPSTMRMTVADGTV---YIAQQMHF 112

Query: 117 HW--SDLPYKGSEHSLDGEHFAMEMHIVHEKEKGTSRNVKEAQDPEDEIAVLAFLVEAGT 174
           HW  +     GSEH++DG    +E+HIVH   K  S ++  AQD  D +AVLA  VE   
Sbjct: 113 HWGGASSEISGSEHTVDGIRHVIEIHIVHYNSKYKSYDI--AQDAPDGLAVLAAFVEVKN 170

Query: 175 QV-NEGFQPLVEALSNIPKPEMSTTMAESSLLDLLPKEEKLRHYFRYLGSLTTPTCDEKV 233
              N  +   +  L+NI  P   TT+    + D+LP+   L+HY+ Y GSLTTP C E V
Sbjct: 171 YPENTYYSNFISHLANIKYPGQRTTLTGLDVQDMLPRN--LQHYYTYHGSLTTPPCTENV 228

Query: 234 VWTVFREPIQLHREQILAFSQKLYYDKEQTVSMKDNVRPLQQLGQRTVIKSGAPGR 289
            W V  + ++L R Q+      L   + +T+   ++ R  Q L  R V++S  P +
Sbjct: 229 HWFVLADFVKLSRTQVWKLENSLLDHRNKTI--HNDYRRTQPLNHR-VVESNFPNQ 281


>gi|4885101 carbonic anhydrase VII isoform 1 [Homo sapiens]
          Length = 264

 Score =  130 bits (328), Expect = 1e-30
 Identities = 92/266 (34%), Positives = 133/266 (50%), Gaps = 21/266 (7%)

Query: 23  WCYEVQAESSNYPCLVPVKWGGNCQKDRQSPINIVTTKAKVDKKLGRFFFSGYDKKQTWT 82
           W Y      S++  L P+  G     DRQSPINI++++A     L     S Y+   + +
Sbjct: 7   WGYGQDDGPSHWHKLYPIAQG-----DRQSPINIISSQAVYSPSLQPLELS-YEACMSLS 60

Query: 83  VQNNGHSVMMLL---ENKASISGGGLPAPYQAKQLHLHWSDLPYKGSEHSLDGEHFAMEM 139
           + NNGHSV +     +++  ++GG L  PY+ KQ H HW      GSEH++DG+ F  E+
Sbjct: 61  ITNNGHSVQVDFNDSDDRTVVTGGPLEGPYRLKQFHFHWGKKHDVGSEHTVDGKSFPSEL 120

Query: 140 HIVHEKEKGTSRNVKEAQDPEDEIAVLAFLVEAGTQVNEGFQPLVEALSNIPKPEMSTTM 199
           H+VH   K  S    EA    D +AV+   +E G + +     L +AL  +       T 
Sbjct: 121 HLVHWNAKKYS-TFGEAASAPDGLAVVGVFLETGDE-HPSMNRLTDALYMV---RFKGTK 175

Query: 200 AESSLLD---LLPKEEKLRHYFRYLGSLTTPTCDEKVVWTVFREPIQLHREQILAFSQKL 256
           A+ S  +   LLP     RHY+ Y GSLTTP   E V W V REPI +   Q+  F   L
Sbjct: 176 AQFSCFNPKCLLPAS---RHYWTYPGSLTTPPLSESVTWIVLREPICISERQMGKFRSLL 232

Query: 257 Y-YDKEQTVSMKDNVRPLQQLGQRTV 281
           +  + ++ + M +N RP Q L  R V
Sbjct: 233 FTSEDDERIHMVNNFRPPQPLKGRVV 258


>gi|194097398 protein tyrosine phosphatase, receptor type, G
           precursor [Homo sapiens]
          Length = 1445

 Score =  126 bits (317), Expect = 2e-29
 Identities = 86/284 (30%), Positives = 135/284 (47%), Gaps = 17/284 (5%)

Query: 9   ALSAARPSASAESHWCYEVQAESSNYPCLVPVKWGGNCQKDRQSPINIVTTKAKVDKKLG 68
           A+   R  AS + +W Y       ++     V    +C    QSPI+I+   A+V ++  
Sbjct: 46  AVQIRRRKASGDPYWAYSGAYGPEHW-----VTSSVSCGGRHQSPIDILDQYARVGEEYQ 100

Query: 69  RFFFSGYDKK---QTWTVQNNGHSVMMLLENKASISGGGLPAPYQAKQLHLHWSDLPYK- 124
                G+D +   +TW ++N G +V +LL++   +SG GLP  ++A+++  HW       
Sbjct: 101 ELQLDGFDNESSNKTW-MKNTGKTVAILLKDDYFVSGAGLPGRFKAEKVEFHWGHSNGSA 159

Query: 125 GSEHSLDGEHFAMEMHIVHEKEKGTSRNVKEAQDPEDEIAVLAFLVEAGTQVNEGFQPLV 184
           GSEHS++G  F +EM I          + + A      I  +A   +   + N    P++
Sbjct: 160 GSEHSINGRRFPVEMQIFFYNPDDFD-SFQTAISENRIIGAMAIFFQVSPRDNSALDPII 218

Query: 185 EALSNIPKPEMSTTMAESSLLDLLPKEEKLRHYFRYLGSLTTPTCDEKVVWTVFREPIQL 244
             L  +   E  T +    L DLLP    L  Y+RY GSLTTP C E V W VFR P+ +
Sbjct: 219 HGLKGVVHHEKETFLDPFVLRDLLPAS--LGSYYRYTGSLTTPPCSEIVEWIVFRRPVPI 276

Query: 245 HREQILAFSQKLYYDKEQTVS----MKDNVRPLQQLGQRTVIKS 284
              Q+ AF      +++  V     +++N RP Q+L  R V KS
Sbjct: 277 SYHQLEAFYSIFTTEQQDHVKSVEYLRNNFRPQQRLHDRVVSKS 320


>gi|4557395 carbonic anhydrase II [Homo sapiens]
          Length = 260

 Score =  123 bits (308), Expect = 2e-28
 Identities = 91/265 (34%), Positives = 129/265 (48%), Gaps = 18/265 (6%)

Query: 22  HWCYEVQAESSNYPCLVPVKWGGNCQKDRQSPINIVTTKAKVDKKLGRFFFSGYDKKQTW 81
           HW Y       ++    P+  G     +RQSP++I T  AK D  L     S YD+  + 
Sbjct: 4   HWGYGKHNGPEHWHKDFPIAKG-----ERQSPVDIDTHTAKYDPSLKPLSVS-YDQATSL 57

Query: 82  TVQNNGHSVMMLLEN---KASISGGGLPAPYQAKQLHLHWSDLPYKGSEHSLDGEHFAME 138
            + NNGH+  +  ++   KA + GG L   Y+  Q H HW  L  +GSEH++D + +A E
Sbjct: 58  RILNNGHAFNVEFDDSQDKAVLKGGPLDGTYRLIQFHFHWGSLDGQGSEHTVDKKKYAAE 117

Query: 139 MHIVHEKEKGTSRNVKEAQDPEDEIAVLAFLVEAGTQVNEGFQPLVEALSNIPKPEMSTT 198
           +H+VH   K      K  Q P D +AVL   ++ G+    G Q +V+ L +I     S  
Sbjct: 118 LHLVHWNTKYGDFG-KAVQQP-DGLAVLGIFLKVGS-AKPGLQKVVDVLDSIKTKGKSAD 174

Query: 199 MAESSLLDLLPKEEKLRHYFRYLGSLTTPTCDEKVVWTVFREPIQLHREQILAFSQKLYY 258
                   LLP+      Y+ Y GSLTTP   E V W V +EPI +  EQ+L F +KL +
Sbjct: 175 FTNFDPRGLLPES---LDYWTYPGSLTTPPLLECVTWIVLKEPISVSSEQVLKF-RKLNF 230

Query: 259 --DKEQTVSMKDNVRPLQQLGQRTV 281
             + E    M DN RP Q L  R +
Sbjct: 231 NGEGEPEELMVDNWRPAQPLKNRQI 255


>gi|38348436 carbonic anhydrase XIII [Homo sapiens]
          Length = 262

 Score =  121 bits (303), Expect = 9e-28
 Identities = 82/237 (34%), Positives = 114/237 (48%), Gaps = 10/237 (4%)

Query: 49  DRQSPINIVTTKAKVDKKLGRFFFSGYDKKQTWTVQNNGHSVMMLL---ENKASISGGGL 105
           D+QSPI I T + K D  L R     YD      + N+GHS  +     ENK+ + GG L
Sbjct: 27  DQQSPIEIKTKEVKYDSSL-RPLSIKYDPSSAKIISNSGHSFNVDFDDTENKSVLRGGPL 85

Query: 106 PAPYQAKQLHLHWSDLPYKGSEHSLDGEHFAMEMHIVHEKEKGTSRNVKEAQDPEDEIAV 165
              Y+ +Q+HLHW      GSEH +DG  +A E+H+VH         V+ A +P D +AV
Sbjct: 86  TGSYRLRQVHLHWGSADDHGSEHIVDGVSYAAELHVVHWNSDKYPSFVEAAHEP-DGLAV 144

Query: 166 LAFLVEAGTQVNEGFQPLVEALSNIPKPEMSTTMAESSLLDLLPKEEKLRHYFRYLGSLT 225
           L   ++ G + N   Q + + L +I +    T      LL LLP       Y+ Y GSLT
Sbjct: 145 LGVFLQIG-EPNSQLQKITDTLDSIKEKGKQTRFTNFDLLSLLPPS---WDYWTYPGSLT 200

Query: 226 TPTCDEKVVWTVFREPIQLHREQILAFSQKL-YYDKEQTVSMKDNVRPLQQLGQRTV 281
            P   E V W V ++PI +  +Q+  F   L   + E    +  N RP Q L  R V
Sbjct: 201 VPPLLESVTWIVLKQPINISSQQLAKFRSLLCTAEGEAAAFLVSNHRPPQPLKGRKV 257


>gi|4885099 carbonic anhydrase III [Homo sapiens]
          Length = 260

 Score =  120 bits (302), Expect = 1e-27
 Identities = 77/241 (31%), Positives = 118/241 (48%), Gaps = 11/241 (4%)

Query: 45  NCQKDRQSPINIVTTKAKVDKKLGRFFFSGYDKKQTWTVQNNGHSVMMLLEN---KASIS 101
           N + + QSP+ + T   + D  L  +  S YD     T+ NNG +  ++ ++   ++ + 
Sbjct: 22  NAKGENQSPVELHTKDIRHDPSLQPWSVS-YDGGSAKTILNNGKTCRVVFDDTYDRSMLR 80

Query: 102 GGGLPAPYQAKQLHLHWSDLPYKGSEHSLDGEHFAMEMHIVHEKEKGTSRNVKEAQDPED 161
           GG LP PY+ +Q HLHW      GSEH++DG  +A E+H+VH   K      KEA    D
Sbjct: 81  GGPLPGPYRLRQFHLHWGSSDDHGSEHTVDGVKYAAELHLVHWNPK--YNTFKEALKQRD 138

Query: 162 EIAVLAFLVEAGTQVNEGFQPLVEALSNIPKPEMSTTMAESSLLDLLPKEEKLRHYFRYL 221
            IAV+   ++ G + N  FQ  ++AL  I          +     L P     R Y+ Y 
Sbjct: 139 GIAVIGIFLKIGHE-NGEFQIFLDALDKIKTKGKEAPFTKFDPSCLFP---ACRDYWTYQ 194

Query: 222 GSLTTPTCDEKVVWTVFREPIQLHREQILAFSQKL-YYDKEQTVSMKDNVRPLQQLGQRT 280
           GS TTP C+E +VW + +EP+ +  +Q+      L   + E  V +  N RP Q +  R 
Sbjct: 195 GSFTTPPCEECIVWLLLKEPMTVSSDQMAKLRSLLSSAENEPPVPLVSNWRPPQPINNRV 254

Query: 281 V 281
           V
Sbjct: 255 V 255


>gi|6005723 carbonic anhydrase VB, mitochondrial precursor [Homo
           sapiens]
          Length = 317

 Score =  116 bits (290), Expect = 3e-26
 Identities = 82/240 (34%), Positives = 118/240 (49%), Gaps = 10/240 (4%)

Query: 49  DRQSPINIVTTKAKVDKKLGRFFFSGYDKKQTWTVQNNGHSVMMLLEN---KASISGGGL 105
           DRQSPINI    +  D  L     S YD      V NNG+S ++  E+   K+ I GG L
Sbjct: 62  DRQSPINIRWRDSVYDPGLKPLTIS-YDPATCLHVWNNGYSFLVEFEDSTDKSVIKGGPL 120

Query: 106 PAPYQAKQLHLHWSDLPYKGSEHSLDGEHFAMEMHIVHEKEKGTSRNVKEAQDPEDEIAV 165
              Y+ KQ H HW  +   GSEH++D + F  E+H+VH        N ++A   E+ +AV
Sbjct: 121 EHNYRLKQFHFHWGAIDAWGSEHTVDSKCFPAELHLVHWNAV-RFENFEDAALEENGLAV 179

Query: 166 LAFLVEAGTQVNEGFQPLVEALSNIPKPEMSTTMAESSLLDLLPKEEKLRHYFRYLGSLT 225
           +   ++ G    E  Q LV+ L +I   +            L+P       Y+ Y GSLT
Sbjct: 180 IGVFLKLGKHHKE-LQKLVDTLPSIKHKDALVEFGSFDPSCLMP---TCPDYWTYSGSLT 235

Query: 226 TPTCDEKVVWTVFREPIQLHREQILAFSQKLYYDK-EQTVSMKDNVRPLQQLGQRTVIKS 284
           TP   E V W + ++P+++  +Q+  F   L+  + E+   M DN RPLQ L  RTV  S
Sbjct: 236 TPPLSESVTWIIKKQPVEVDHDQLEQFRTLLFTSEGEKEKRMVDNFRPLQPLMNRTVRSS 295


>gi|62240989 carbonic anhydrase VII isoform 2 [Homo sapiens]
          Length = 208

 Score =  112 bits (280), Expect = 4e-25
 Identities = 74/207 (35%), Positives = 106/207 (51%), Gaps = 15/207 (7%)

Query: 82  TVQNNGHSVMMLL---ENKASISGGGLPAPYQAKQLHLHWSDLPYKGSEHSLDGEHFAME 138
           ++ NNGHSV +     +++  ++GG L  PY+ KQ H HW      GSEH++DG+ F  E
Sbjct: 4   SITNNGHSVQVDFNDSDDRTVVTGGPLEGPYRLKQFHFHWGKKHDVGSEHTVDGKSFPSE 63

Query: 139 MHIVHEKEKGTSRNVKEAQDPEDEIAVLAFLVEAGTQVNEGFQPLVEALSNIPKPEMSTT 198
           +H+VH   K  S    EA    D +AV+   +E G + +     L +AL  +       T
Sbjct: 64  LHLVHWNAKKYS-TFGEAASAPDGLAVVGVFLETGDE-HPSMNRLTDALYMV---RFKGT 118

Query: 199 MAESSLLD---LLPKEEKLRHYFRYLGSLTTPTCDEKVVWTVFREPIQLHREQILAFSQK 255
            A+ S  +   LLP     RHY+ Y GSLTTP   E V W V REPI +   Q+  F   
Sbjct: 119 KAQFSCFNPKCLLPAS---RHYWTYPGSLTTPPLSESVTWIVLREPICISERQMGKFRSL 175

Query: 256 LY-YDKEQTVSMKDNVRPLQQLGQRTV 281
           L+  + ++ + M +N RP Q L  R V
Sbjct: 176 LFTSEDDERIHMVNNFRPPQPLKGRVV 202


>gi|91208428 protein tyrosine phosphatase, receptor-type, zeta1
           precursor [Homo sapiens]
          Length = 2315

 Score =  111 bits (278), Expect = 7e-25
 Identities = 78/274 (28%), Positives = 129/274 (47%), Gaps = 18/274 (6%)

Query: 20  ESHWCYEVQAESSNYPCLVPVKWGGNCQKDRQSPINIVTTKAKVDKKLGRFFFSGYDKK- 78
           E  W Y       N+    P      C   +QSPINI     +V+  L +  F G+DK  
Sbjct: 35  EIGWSYTGALNQKNWGKKYPT-----CNSPKQSPINIDEDLTQVNVNLKKLKFQGWDKTS 89

Query: 79  -QTWTVQNNGHSVMMLLENKASISGGGLPAPYQAKQLHLHWS--DLPYKGSEHSLDGEHF 135
            +   + N G +V + L N   +SGG     ++A ++  HW   ++   GSEHSL+G+ F
Sbjct: 90  LENTFIHNTGKTVEINLTNDYRVSGGVSEMVFKASKITFHWGKCNMSSDGSEHSLEGQKF 149

Query: 136 AMEMHIV-HEKEKGTSRNVKEAQDPEDEIAVLAFLVEAGTQVNEGFQPLVEALSNIPKPE 194
            +EM I   + ++ +S   +EA   + ++  L+ L E GT+ N  F+ +++ + ++ +  
Sbjct: 150 PLEMQIYCFDADRFSS--FEEAVKGKGKLRALSILFEVGTEENLDFKAIIDGVESVSRFG 207

Query: 195 MSTTMAESSLLDLLPKEEKLRHYFRYLGSLTTPTCDEKVVWTVFREPIQLHREQILAFSQ 254
               +    LL+LLP       Y+ Y GSLT+P C + V W VF++ + +   Q+  F +
Sbjct: 208 KQAALDPFILLNLLPNSTD--KYYIYNGSLTSPPCTDTVDWIVFKDTVSISESQLAVFCE 265

Query: 255 KLYYDKEQTVSMKD----NVRPLQQLGQRTVIKS 284
            L   +   V + D    N R  Q    R V  S
Sbjct: 266 VLTMQQSGYVMLMDYLQNNFREQQYKFSRQVFSS 299


>gi|169636420 carbonic anhydrase IX precursor [Homo sapiens]
          Length = 459

 Score =  111 bits (277), Expect = 9e-25
 Identities = 83/271 (30%), Positives = 122/271 (45%), Gaps = 17/271 (6%)

Query: 20  ESHWCYEVQAESSNYPCLVPVKWGGNCQKDRQSPINIVTTKAKVDKKLGRFFFSGYDKKQ 79
           +SHW Y        +P + P      C    QSP++I    A     L      G+    
Sbjct: 138 QSHWRY---GGDPPWPRVSPA-----CAGRFQSPVDIRPQLAAFCPALRPLELLGFQLPP 189

Query: 80  T--WTVQNNGHSVMMLLENKASISGGGLPAPYQAKQLHLHWSDLPYKGSEHSLDGEHFAM 137
                ++NNGHSV + L     ++ G     Y+A QLHLHW      GSEH+++G  F  
Sbjct: 190 LPELRLRNNGHSVQLTLPPGLEMALGP-GREYRALQLHLHWGAAGRPGSEHTVEGHRFPA 248

Query: 138 EMHIVHEKEKGTSRNVKEAQDPEDEIAVLAFLVEAGTQVNEGFQPLVEALSNIPKPEMST 197
           E+H+VH         V EA      +AVLA  +E G + N  ++ L+  L  I +    T
Sbjct: 249 EIHVVHLST--AFARVDEALGRPGGLAVLAAFLEEGPEENSAYEQLLSRLEEIAEEGSET 306

Query: 198 TMAESSLLDLLPKEEKLRHYFRYLGSLTTPTCDEKVVWTVFREPIQLHREQILAFSQKLY 257
            +    +  LLP +     YF+Y GSLTTP C + V+WTVF + + L  +Q+   S  L+
Sbjct: 307 QVPGLDISALLPSD--FSRYFQYEGSLTTPPCAQGVIWTVFNQTVMLSAKQLHTLSDTLW 364

Query: 258 YDKEQTVSMKDNVRPLQQLGQRTVIKSGAPG 288
              +  + +  N R  Q L  R +  S   G
Sbjct: 365 GPGDSRLQL--NFRATQPLNGRVIEASFPAG 393


>gi|22027500 carbonic anhydrase VIII [Homo sapiens]
          Length = 290

 Score =  109 bits (273), Expect = 3e-24
 Identities = 78/254 (30%), Positives = 131/254 (51%), Gaps = 15/254 (5%)

Query: 40  VKWG---GNCQKDRQSPINIVTTKAKVDKKLGRFFFS-GYDKKQTWTVQNNGHSVMMLLE 95
           V+WG    +   + QSPIN+ + +A+ D  L     S  Y   +   V N+GH++ ++L+
Sbjct: 35  VEWGLVFPDANGEYQSPINLNSREARYDPSLLDVRLSPNYVVCRDCEVTNDGHTIQVILK 94

Query: 96  NKASISGGGLPAPYQAK--QLHLHWSDLPYKGSEHSLDGEHFAMEMHIVHEKEKGTSRNV 153
           +K+ +SGG LP  ++ +  ++  HW     +GSEH+++ + F ME+H++H        ++
Sbjct: 95  SKSVLSGGPLPQGHEFELYEVRFHWGRENQRGSEHTVNFKAFPMELHLIHWNST-LFGSI 153

Query: 154 KEAQDPEDEIAVLAFLVEAGTQVNEGFQPLVEALSNIPKPEMSTTMAESSLLDLLPKEEK 213
            EA      IA++A  V+ G + + G + + E L +I     S T+   +   LLP +  
Sbjct: 154 DEAVGKPHGIAIIALFVQIGKE-HVGLKAVTEILQDIQYKGKSKTIPCFNPNTLLP-DPL 211

Query: 214 LRHYFRYLGSLTTPTCDEKVVWTVFREPIQLHREQILAFSQKLYYDKEQTV------SMK 267
           LR Y+ Y GSLT P C E V W +FR P+ + + QI  F +   + K   +       + 
Sbjct: 212 LRDYWVYEGSLTIPPCSEGVTWILFRYPLTISQLQIEEFRRLRTHVKGAELVEGCDGILG 271

Query: 268 DNVRPLQQLGQRTV 281
           DN RP Q L  R +
Sbjct: 272 DNFRPTQPLSDRVI 285


>gi|4502521 carbonic anhydrase VA, mitochondrial precursor [Homo
           sapiens]
          Length = 305

 Score =  108 bits (270), Expect = 6e-24
 Identities = 86/273 (31%), Positives = 126/273 (46%), Gaps = 14/273 (5%)

Query: 14  RPSASAESHWCYEVQAESSNYPC-LVPVKWGGNCQKDRQSPINIVTTKAKVDKKLGRFFF 72
           RP        C    + ++ +P   VPV   G     RQSPINI    +  D +L     
Sbjct: 29  RPGRWCSQRSCAWQTSNNTLHPLWTVPVSVPGGT---RQSPINIQWRDSVYDPQLKPLRV 85

Query: 73  SGYDKKQTWTVQNNGHSVMMLLENK---ASISGGGLPAPYQAKQLHLHWSDLPYKGSEHS 129
           S Y+      + N G+   +  ++    + ISGG L   Y+ KQ H HW  +   GSEH+
Sbjct: 86  S-YEAASCLYIWNTGYLFQVEFDDATEASGISGGPLENHYRLKQFHFHWGAVNEGGSEHT 144

Query: 130 LDGEHFAMEMHIVHEKEKGTSRNVKEAQDPEDEIAVLAFLVEAGTQVNEGFQPLVEALSN 189
           +DG  +  E+H+VH       +N KEA   E+ +AV+   ++ G   ++  Q LV+ L  
Sbjct: 145 VDGHAYPAELHLVHWNSV-KYQNYKEAVVGENGLAVIGVFLKLGAH-HQTLQRLVDILPE 202

Query: 190 IPKPEMSTTMAESSLLDLLPKEEKLRHYFRYLGSLTTPTCDEKVVWTVFREPIQLHREQI 249
           I   +    M       LLP       Y+ Y GSLTTP   E V W + +EP+++   Q+
Sbjct: 203 IKHKDARAAMRPFDPSTLLP---TCWDYWTYAGSLTTPPLTESVTWIIQKEPVEVAPSQL 259

Query: 250 LAFSQKLYYD-KEQTVSMKDNVRPLQQLGQRTV 281
            AF   L+    E+   M +N RPLQ L  R V
Sbjct: 260 SAFRTLLFSALGEEEKMMVNNYRPLQPLMNRKV 292


>gi|192447434 carbonic anhydrase I [Homo sapiens]
          Length = 261

 Score =  106 bits (265), Expect = 2e-23
 Identities = 80/267 (29%), Positives = 120/267 (44%), Gaps = 15/267 (5%)

Query: 19  AESHWCYEVQAESSNYPCLVPVKWGGNCQKDRQSPINIVTTKAKVDKKLGRFFFSGYDKK 78
           A   W Y+ +     +  L P+  G N     QSP++I T++ K D  L     S Y+  
Sbjct: 2   ASPDWGYDDKNGPEQWSKLYPIANGNN-----QSPVDIKTSETKHDTSLKPISVS-YNPA 55

Query: 79  QTWTVQNNGHSVMMLLE---NKASISGGGLPAPYQAKQLHLHWSDLPYKGSEHSLDGEHF 135
               + N GHS  +  E   N++ + GG     Y+  Q H HW      GSEH++DG  +
Sbjct: 56  TAKEIINVGHSFHVNFEDNDNRSVLKGGPFSDSYRLFQFHFHWGSTNEHGSEHTVDGVKY 115

Query: 136 AMEMHIVHEKEKGTSRNVKEAQDPEDEIAVLAFLVEAGTQVNEGFQPLVEALSNIPKPEM 195
           + E+H+ H      S ++ EA    D +AV+  L++ G + N   Q +++AL  I     
Sbjct: 116 SAELHVAHWNSAKYS-SLAEAASKADGLAVIGVLMKVG-EANPKLQKVLDALQAIKTKGK 173

Query: 196 STTMAESSLLDLLPKEEKLRHYFRYLGSLTTPTCDEKVVWTVFREPIQLHREQILAFSQK 255
                      LLP       ++ Y GSLT P   E V W + +E I +  EQ+  F   
Sbjct: 174 RAPFTNFDPSTLLPSS---LDFWTYPGSLTHPPLYESVTWIICKESISVSSEQLAQFRSL 230

Query: 256 L-YYDKEQTVSMKDNVRPLQQLGQRTV 281
           L   + +  V M+ N RP Q L  RTV
Sbjct: 231 LSNVEGDNAVPMQHNNRPTQPLKGRTV 257


>gi|192447432 carbonic anhydrase I [Homo sapiens]
          Length = 261

 Score =  106 bits (265), Expect = 2e-23
 Identities = 80/267 (29%), Positives = 120/267 (44%), Gaps = 15/267 (5%)

Query: 19  AESHWCYEVQAESSNYPCLVPVKWGGNCQKDRQSPINIVTTKAKVDKKLGRFFFSGYDKK 78
           A   W Y+ +     +  L P+  G N     QSP++I T++ K D  L     S Y+  
Sbjct: 2   ASPDWGYDDKNGPEQWSKLYPIANGNN-----QSPVDIKTSETKHDTSLKPISVS-YNPA 55

Query: 79  QTWTVQNNGHSVMMLLE---NKASISGGGLPAPYQAKQLHLHWSDLPYKGSEHSLDGEHF 135
               + N GHS  +  E   N++ + GG     Y+  Q H HW      GSEH++DG  +
Sbjct: 56  TAKEIINVGHSFHVNFEDNDNRSVLKGGPFSDSYRLFQFHFHWGSTNEHGSEHTVDGVKY 115

Query: 136 AMEMHIVHEKEKGTSRNVKEAQDPEDEIAVLAFLVEAGTQVNEGFQPLVEALSNIPKPEM 195
           + E+H+ H      S ++ EA    D +AV+  L++ G + N   Q +++AL  I     
Sbjct: 116 SAELHVAHWNSAKYS-SLAEAASKADGLAVIGVLMKVG-EANPKLQKVLDALQAIKTKGK 173

Query: 196 STTMAESSLLDLLPKEEKLRHYFRYLGSLTTPTCDEKVVWTVFREPIQLHREQILAFSQK 255
                      LLP       ++ Y GSLT P   E V W + +E I +  EQ+  F   
Sbjct: 174 RAPFTNFDPSTLLPSS---LDFWTYPGSLTHPPLYESVTWIICKESISVSSEQLAQFRSL 230

Query: 256 L-YYDKEQTVSMKDNVRPLQQLGQRTV 281
           L   + +  V M+ N RP Q L  RTV
Sbjct: 231 LSNVEGDNAVPMQHNNRPTQPLKGRTV 257


>gi|192447430 carbonic anhydrase I [Homo sapiens]
          Length = 261

 Score =  106 bits (265), Expect = 2e-23
 Identities = 80/267 (29%), Positives = 120/267 (44%), Gaps = 15/267 (5%)

Query: 19  AESHWCYEVQAESSNYPCLVPVKWGGNCQKDRQSPINIVTTKAKVDKKLGRFFFSGYDKK 78
           A   W Y+ +     +  L P+  G N     QSP++I T++ K D  L     S Y+  
Sbjct: 2   ASPDWGYDDKNGPEQWSKLYPIANGNN-----QSPVDIKTSETKHDTSLKPISVS-YNPA 55

Query: 79  QTWTVQNNGHSVMMLLE---NKASISGGGLPAPYQAKQLHLHWSDLPYKGSEHSLDGEHF 135
               + N GHS  +  E   N++ + GG     Y+  Q H HW      GSEH++DG  +
Sbjct: 56  TAKEIINVGHSFHVNFEDNDNRSVLKGGPFSDSYRLFQFHFHWGSTNEHGSEHTVDGVKY 115

Query: 136 AMEMHIVHEKEKGTSRNVKEAQDPEDEIAVLAFLVEAGTQVNEGFQPLVEALSNIPKPEM 195
           + E+H+ H      S ++ EA    D +AV+  L++ G + N   Q +++AL  I     
Sbjct: 116 SAELHVAHWNSAKYS-SLAEAASKADGLAVIGVLMKVG-EANPKLQKVLDALQAIKTKGK 173

Query: 196 STTMAESSLLDLLPKEEKLRHYFRYLGSLTTPTCDEKVVWTVFREPIQLHREQILAFSQK 255
                      LLP       ++ Y GSLT P   E V W + +E I +  EQ+  F   
Sbjct: 174 RAPFTNFDPSTLLPSS---LDFWTYPGSLTHPPLYESVTWIICKESISVSSEQLAQFRSL 230

Query: 256 L-YYDKEQTVSMKDNVRPLQQLGQRTV 281
           L   + +  V M+ N RP Q L  RTV
Sbjct: 231 LSNVEGDNAVPMQHNNRPTQPLKGRTV 257


>gi|4502517 carbonic anhydrase I [Homo sapiens]
          Length = 261

 Score =  106 bits (265), Expect = 2e-23
 Identities = 80/267 (29%), Positives = 120/267 (44%), Gaps = 15/267 (5%)

Query: 19  AESHWCYEVQAESSNYPCLVPVKWGGNCQKDRQSPINIVTTKAKVDKKLGRFFFSGYDKK 78
           A   W Y+ +     +  L P+  G N     QSP++I T++ K D  L     S Y+  
Sbjct: 2   ASPDWGYDDKNGPEQWSKLYPIANGNN-----QSPVDIKTSETKHDTSLKPISVS-YNPA 55

Query: 79  QTWTVQNNGHSVMMLLE---NKASISGGGLPAPYQAKQLHLHWSDLPYKGSEHSLDGEHF 135
               + N GHS  +  E   N++ + GG     Y+  Q H HW      GSEH++DG  +
Sbjct: 56  TAKEIINVGHSFHVNFEDNDNRSVLKGGPFSDSYRLFQFHFHWGSTNEHGSEHTVDGVKY 115

Query: 136 AMEMHIVHEKEKGTSRNVKEAQDPEDEIAVLAFLVEAGTQVNEGFQPLVEALSNIPKPEM 195
           + E+H+ H      S ++ EA    D +AV+  L++ G + N   Q +++AL  I     
Sbjct: 116 SAELHVAHWNSAKYS-SLAEAASKADGLAVIGVLMKVG-EANPKLQKVLDALQAIKTKGK 173

Query: 196 STTMAESSLLDLLPKEEKLRHYFRYLGSLTTPTCDEKVVWTVFREPIQLHREQILAFSQK 255
                      LLP       ++ Y GSLT P   E V W + +E I +  EQ+  F   
Sbjct: 174 RAPFTNFDPSTLLPSS---LDFWTYPGSLTHPPLYESVTWIICKESISVSSEQLAQFRSL 230

Query: 256 L-YYDKEQTVSMKDNVRPLQQLGQRTV 281
           L   + +  V M+ N RP Q L  RTV
Sbjct: 231 LSNVEGDNAVPMQHNNRPTQPLKGRTV 257


>gi|130979954 carbonic anhydrase X [Homo sapiens]
          Length = 328

 Score = 96.3 bits (238), Expect = 3e-20
 Identities = 77/291 (26%), Positives = 134/291 (46%), Gaps = 25/291 (8%)

Query: 7   LLALSAARPSASA-ESHWCYEVQAESSNYPC-----LVPVKWGGNCQKDRQSPINIVTTK 60
           ++ +SA + S    E  W Y+   + S  P      LV   W       RQSP+NI T+ 
Sbjct: 16  IVCISAQQNSPKIHEGWWAYKEVVQGSFVPVPSFWGLVNSAWNLCSVGKRQSPVNIETSH 75

Query: 61  AKVDKKLGRFFFSGYDKKQTWTVQNNGHSVMMLL--ENKASISGGGLPAPYQAKQLHLHW 118
              D  L     +   +K + T+ N G  V + L  E+  +ISGG +   ++ +++ LH+
Sbjct: 76  MIFDPFLTPLRINTGGRKVSGTMYNTGRHVSLRLDKEHLVNISGGPMTYSHRLEEIRLHF 135

Query: 119 SDLPYKGSEHSLDGEHFAMEMHIVHEKEKGTSRNVKEAQDPEDEIAVLAFLVEAGTQVNE 178
                +GSEH L+G+ F+ E+ ++H   +  +   + A+ P   + V  F+     +V++
Sbjct: 136 GSEDSQGSEHLLNGQAFSGEVQLIHYNHELYTNVTEAAKSPNGLVVVSIFI-----KVSD 190

Query: 179 GFQPLVEALSNIPKPEMSTTMAESSLLDLLPKEE---KLRHYFRYLGSLTTPTCDEKVVW 235
              P +  + N       T   ++ LL  L  EE   +   +  Y GS+T P C E   W
Sbjct: 191 SSNPFLNRMLNRDTITRITYKNDAYLLQGLNIEELYPETSSFITYDGSMTIPPCYETASW 250

Query: 236 TVFREPI-----QLHREQILAFSQKLYYDKEQTVSMKDNVRPLQQLGQRTV 281
            +  +P+     Q+H  ++L+ +Q      +  +SM DN RP+Q L  R +
Sbjct: 251 IIMNKPVYITRMQMHSLRLLSQNQ----PSQIFLSMSDNFRPVQPLNNRCI 297


>gi|130979679 carbonic anhydrase X [Homo sapiens]
          Length = 328

 Score = 96.3 bits (238), Expect = 3e-20
 Identities = 77/291 (26%), Positives = 134/291 (46%), Gaps = 25/291 (8%)

Query: 7   LLALSAARPSASA-ESHWCYEVQAESSNYPC-----LVPVKWGGNCQKDRQSPINIVTTK 60
           ++ +SA + S    E  W Y+   + S  P      LV   W       RQSP+NI T+ 
Sbjct: 16  IVCISAQQNSPKIHEGWWAYKEVVQGSFVPVPSFWGLVNSAWNLCSVGKRQSPVNIETSH 75

Query: 61  AKVDKKLGRFFFSGYDKKQTWTVQNNGHSVMMLL--ENKASISGGGLPAPYQAKQLHLHW 118
              D  L     +   +K + T+ N G  V + L  E+  +ISGG +   ++ +++ LH+
Sbjct: 76  MIFDPFLTPLRINTGGRKVSGTMYNTGRHVSLRLDKEHLVNISGGPMTYSHRLEEIRLHF 135

Query: 119 SDLPYKGSEHSLDGEHFAMEMHIVHEKEKGTSRNVKEAQDPEDEIAVLAFLVEAGTQVNE 178
                +GSEH L+G+ F+ E+ ++H   +  +   + A+ P   + V  F+     +V++
Sbjct: 136 GSEDSQGSEHLLNGQAFSGEVQLIHYNHELYTNVTEAAKSPNGLVVVSIFI-----KVSD 190

Query: 179 GFQPLVEALSNIPKPEMSTTMAESSLLDLLPKEE---KLRHYFRYLGSLTTPTCDEKVVW 235
              P +  + N       T   ++ LL  L  EE   +   +  Y GS+T P C E   W
Sbjct: 191 SSNPFLNRMLNRDTITRITYKNDAYLLQGLNIEELYPETSSFITYDGSMTIPPCYETASW 250

Query: 236 TVFREPI-----QLHREQILAFSQKLYYDKEQTVSMKDNVRPLQQLGQRTV 281
            +  +P+     Q+H  ++L+ +Q      +  +SM DN RP+Q L  R +
Sbjct: 251 IIMNKPVYITRMQMHSLRLLSQNQ----PSQIFLSMSDNFRPVQPLNNRCI 297


>gi|9910366 carbonic anhydrase X [Homo sapiens]
          Length = 328

 Score = 96.3 bits (238), Expect = 3e-20
 Identities = 77/291 (26%), Positives = 134/291 (46%), Gaps = 25/291 (8%)

Query: 7   LLALSAARPSASA-ESHWCYEVQAESSNYPC-----LVPVKWGGNCQKDRQSPINIVTTK 60
           ++ +SA + S    E  W Y+   + S  P      LV   W       RQSP+NI T+ 
Sbjct: 16  IVCISAQQNSPKIHEGWWAYKEVVQGSFVPVPSFWGLVNSAWNLCSVGKRQSPVNIETSH 75

Query: 61  AKVDKKLGRFFFSGYDKKQTWTVQNNGHSVMMLL--ENKASISGGGLPAPYQAKQLHLHW 118
              D  L     +   +K + T+ N G  V + L  E+  +ISGG +   ++ +++ LH+
Sbjct: 76  MIFDPFLTPLRINTGGRKVSGTMYNTGRHVSLRLDKEHLVNISGGPMTYSHRLEEIRLHF 135

Query: 119 SDLPYKGSEHSLDGEHFAMEMHIVHEKEKGTSRNVKEAQDPEDEIAVLAFLVEAGTQVNE 178
                +GSEH L+G+ F+ E+ ++H   +  +   + A+ P   + V  F+     +V++
Sbjct: 136 GSEDSQGSEHLLNGQAFSGEVQLIHYNHELYTNVTEAAKSPNGLVVVSIFI-----KVSD 190

Query: 179 GFQPLVEALSNIPKPEMSTTMAESSLLDLLPKEE---KLRHYFRYLGSLTTPTCDEKVVW 235
              P +  + N       T   ++ LL  L  EE   +   +  Y GS+T P C E   W
Sbjct: 191 SSNPFLNRMLNRDTITRITYKNDAYLLQGLNIEELYPETSSFITYDGSMTIPPCYETASW 250

Query: 236 TVFREPI-----QLHREQILAFSQKLYYDKEQTVSMKDNVRPLQQLGQRTV 281
            +  +P+     Q+H  ++L+ +Q      +  +SM DN RP+Q L  R +
Sbjct: 251 IIMNKPVYITRMQMHSLRLLSQNQ----PSQIFLSMSDNFRPVQPLNNRCI 297


>gi|9951923 carbonic anhydrase XI precursor [Homo sapiens]
          Length = 328

 Score = 74.7 bits (182), Expect = 1e-13
 Identities = 75/306 (24%), Positives = 128/306 (41%), Gaps = 25/306 (8%)

Query: 2   RMLLALLALSAAR---PSASAESHWCYEVQAESSNYPC-----LVPVKWGGNCQKDRQSP 53
           R L+   AL AA    P+   E  W Y+   + +  P      LV   W       RQSP
Sbjct: 11  RALVLWAALGAAAHIGPAPDPEDWWSYKDNLQGNFVPGPPFWGLVNAAWSLCAVGKRQSP 70

Query: 54  INIVTTKAKVDKKLGRFFFSGYDKKQTWTVQNNGHSVMMLLENK--ASISGGGLPAPYQA 111
           +++   +   D  L     S   +K   T+ N G  V  L   +   ++SGG L   ++ 
Sbjct: 71  VDVELKRVLYDPFLPPLRLSTGGEKLRGTLYNTGRHVSFLPAPRPVVNVSGGPLLYSHRL 130

Query: 112 KQLHLHWSDLPYKGSEHSLDGEHFAMEMHIVHEKEKGTSRNVKEAQDPEDEIAVLAFLVE 171
            +L L +      GSEH ++ + F+ E+ ++H  ++    N   A    + +A+L+  V 
Sbjct: 131 SELRLLFGARDGAGSEHQINHQGFSAEVQLIHFNQE-LYGNFSAASRGPNGLAILSLFVN 189

Query: 172 AGTQVNEGFQPLV--EALSNIPKPEMSTTMAESSLLDLLPKEEKLRHYFRYLGSLTTPTC 229
             +  N     L+  + ++ I     +  + + SL  L P+      +  Y GSL+TP C
Sbjct: 190 VASTSNPFLSRLLNRDTITRISYKNDAYFLQDLSLELLFPES---FGFITYQGSLSTPPC 246

Query: 230 DEKVVWTVFRE-----PIQLHREQILAFSQKLYYDKEQTVSMKDNVRPLQQLGQRTVIKS 284
            E V W +         +Q+H  ++L+ +       +   S+  N RPLQ L  R +  +
Sbjct: 247 SETVTWILIDRALNITSLQMHSLRLLSQNP----PSQIFQSLSGNSRPLQPLAHRALRGN 302

Query: 285 GAPGRP 290
             P  P
Sbjct: 303 RDPRHP 308


>gi|239757628 PREDICTED: similar to hCG1646661 [Homo sapiens]
          Length = 190

 Score = 47.0 bits (110), Expect = 2e-05
 Identities = 26/76 (34%), Positives = 37/76 (48%), Gaps = 5/76 (6%)

Query: 177 NEGFQPLVEALSNIPKPEMSTTMAESSLLDLLPKEEKLRHYFRYLGSLTTPTCDEKVVWT 236
           N  F  +V  L  +P+P     M+   L  + P       Y R+ GSLT P C+  V+WT
Sbjct: 68  NTNFCAIVSGLRKVPEPV--NLMSTFPLASMRPNTSS---YCRFAGSLTPPDCEPTVLWT 122

Query: 237 VFREPIQLHREQILAF 252
           VF +PI +   Q+  F
Sbjct: 123 VFEDPIPIRWVQMTLF 138


>gi|239752124 PREDICTED: similar to hCG1646661 [Homo sapiens]
          Length = 190

 Score = 47.0 bits (110), Expect = 2e-05
 Identities = 26/76 (34%), Positives = 37/76 (48%), Gaps = 5/76 (6%)

Query: 177 NEGFQPLVEALSNIPKPEMSTTMAESSLLDLLPKEEKLRHYFRYLGSLTTPTCDEKVVWT 236
           N  F  +V  L  +P+P     M+   L  + P       Y R+ GSLT P C+  V+WT
Sbjct: 68  NTNFCAIVSGLRKVPEPV--NLMSTFPLASMRPNTSS---YCRFAGSLTPPDCEPTVLWT 122

Query: 237 VFREPIQLHREQILAF 252
           VF +PI +   Q+  F
Sbjct: 123 VFEDPIPIRWVQMTLF 138


>gi|239746634 PREDICTED: similar to hCG1646661 [Homo sapiens]
          Length = 190

 Score = 47.0 bits (110), Expect = 2e-05
 Identities = 26/76 (34%), Positives = 37/76 (48%), Gaps = 5/76 (6%)

Query: 177 NEGFQPLVEALSNIPKPEMSTTMAESSLLDLLPKEEKLRHYFRYLGSLTTPTCDEKVVWT 236
           N  F  +V  L  +P+P     M+   L  + P       Y R+ GSLT P C+  V+WT
Sbjct: 68  NTNFCAIVSGLRKVPEPV--NLMSTFPLASMRPNTSS---YCRFAGSLTPPDCEPTVLWT 122

Query: 237 VFREPIQLHREQILAF 252
           VF +PI +   Q+  F
Sbjct: 123 VFEDPIPIRWVQMTLF 138


>gi|239746647 PREDICTED: similar to hCG1646661 [Homo sapiens]
          Length = 190

 Score = 46.6 bits (109), Expect = 3e-05
 Identities = 26/76 (34%), Positives = 37/76 (48%), Gaps = 5/76 (6%)

Query: 177 NEGFQPLVEALSNIPKPEMSTTMAESSLLDLLPKEEKLRHYFRYLGSLTTPTCDEKVVWT 236
           N  F  +V  L  +P+P     M+   L  + P       Y R+ GSLT P C+  V+WT
Sbjct: 68  NTNFCAIVSGLRKVPEPV--NLMSTFLLASMRPNTSS---YCRFAGSLTPPDCEPTVLWT 122

Query: 237 VFREPIQLHREQILAF 252
           VF +PI +   Q+  F
Sbjct: 123 VFEDPIPIRWVQMTLF 138


>gi|239757641 PREDICTED: similar to hCG1646661 [Homo sapiens]
          Length = 190

 Score = 45.4 bits (106), Expect = 6e-05
 Identities = 25/77 (32%), Positives = 38/77 (49%), Gaps = 7/77 (9%)

Query: 177 NEGFQPLVEALSNIPKP-EMSTTMAESSLLDLLPKEEKLRHYFRYLGSLTTPTCDEKVVW 235
           N  F  +V  L  +P+P  + +T   +S+            Y R+ GSLT P C+  V+W
Sbjct: 68  NTNFCAIVSGLRKVPEPVNLRSTFLLASM------RPNTSSYCRFAGSLTPPDCEPTVLW 121

Query: 236 TVFREPIQLHREQILAF 252
           TVF +PI +   Q+  F
Sbjct: 122 TVFEDPIPIRWVQMTLF 138


>gi|50233787 nuclear protein in testis [Homo sapiens]
          Length = 1132

 Score = 30.0 bits (66), Expect = 2.8
 Identities = 16/66 (24%), Positives = 36/66 (54%), Gaps = 1/66 (1%)

Query: 119  SDLPYKGSEHSL-DGEHFAMEMHIVHEKEKGTSRNVKEAQDPEDEIAVLAFLVEAGTQVN 177
            S LP +G+ +++   E    + H   ++ KG  +  KEA++ ++E++  A+L+ +   ++
Sbjct: 972  STLPRRGTRNAIVPRETSVSKTHRSADRAKGKEKKKKEAEEEDEELSNFAYLLASKLSLS 1031

Query: 178  EGFQPL 183
                PL
Sbjct: 1032 PREHPL 1037


  Database: hs.faa
    Posted date:  Aug 4, 2009  4:42 PM
  Number of letters in database: 18,247,518
  Number of sequences in database:  37,866
  
Lambda     K      H
   0.317    0.132    0.400 

Gapped
Lambda     K      H
   0.267   0.0410    0.140 


Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Hits to DB: 12,370,316
Number of Sequences: 37866
Number of extensions: 569102
Number of successful extensions: 1834
Number of sequences better than 10.0: 30
Number of HSP's better than 10.0 without gapping: 30
Number of HSP's successfully gapped in prelim test: 6
Number of HSP's that attempted gapping in prelim test: 1744
Number of HSP's gapped (non-prelim): 37
length of query: 312
length of database: 18,247,518
effective HSP length: 102
effective length of query: 210
effective length of database: 14,385,186
effective search space: 3020889060
effective search space used: 3020889060
T: 11
A: 40
X1: 16 ( 7.3 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 41 (21.7 bits)
S2: 62 (28.5 bits)

Search results were obtained with NCBI BLAST and RefSeq entries.


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Guide to the Human Genome
Copyright © 2010 by Stewart Scherer. All rights reserved.

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