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Search of human proteins with 4502515
BLASTP 2.2.11 [Jun-05-2005]
Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer,
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997),
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs", Nucleic Acids Res. 25:3389-3402.
Query= gi|4502515 carbonic anhydrase XII isoform 1 precursor [Homo
sapiens]
(354 letters)
Database: hs.faa
37,866 sequences; 18,247,518 total letters
Searching..................................................done
Score E
Sequences producing significant alignments: (bits) Value
gi|4502515 carbonic anhydrase XII isoform 1 precursor [Homo sapi... 723 0.0
gi|45935383 carbonic anhydrase XII isoform 2 precursor [Homo sap... 694 0.0
gi|6912284 carbonic anhydrase XIV precursor [Homo sapiens] 267 9e-72
gi|169636420 carbonic anhydrase IX precursor [Homo sapiens] 201 8e-52
gi|70167127 carbonic anhydrase VI precursor [Homo sapiens] 186 2e-47
gi|4885101 carbonic anhydrase VII isoform 1 [Homo sapiens] 168 6e-42
gi|192447434 carbonic anhydrase I [Homo sapiens] 164 1e-40
gi|192447432 carbonic anhydrase I [Homo sapiens] 164 1e-40
gi|192447430 carbonic anhydrase I [Homo sapiens] 164 1e-40
gi|4502517 carbonic anhydrase I [Homo sapiens] 164 1e-40
gi|38348436 carbonic anhydrase XIII [Homo sapiens] 162 3e-40
gi|91208428 protein tyrosine phosphatase, receptor-type, zeta1 p... 158 8e-39
gi|194097398 protein tyrosine phosphatase, receptor type, G prec... 157 1e-38
gi|4557395 carbonic anhydrase II [Homo sapiens] 154 1e-37
gi|4885099 carbonic anhydrase III [Homo sapiens] 150 1e-36
gi|22027500 carbonic anhydrase VIII [Homo sapiens] 142 5e-34
gi|4502519 carbonic anhydrase IV precursor [Homo sapiens] 141 8e-34
gi|62240989 carbonic anhydrase VII isoform 2 [Homo sapiens] 139 3e-33
gi|4502521 carbonic anhydrase VA, mitochondrial precursor [Homo ... 134 1e-31
gi|130979954 carbonic anhydrase X [Homo sapiens] 124 2e-28
gi|130979679 carbonic anhydrase X [Homo sapiens] 124 2e-28
gi|9910366 carbonic anhydrase X [Homo sapiens] 124 2e-28
gi|6005723 carbonic anhydrase VB, mitochondrial precursor [Homo ... 122 4e-28
gi|9951923 carbonic anhydrase XI precursor [Homo sapiens] 97 3e-20
gi|239746647 PREDICTED: similar to hCG1646661 [Homo sapiens] 51 2e-06
gi|239757641 PREDICTED: similar to hCG1646661 [Homo sapiens] 50 3e-06
gi|239757628 PREDICTED: similar to hCG1646661 [Homo sapiens] 50 3e-06
gi|239752124 PREDICTED: similar to hCG1646661 [Homo sapiens] 50 3e-06
gi|239746634 PREDICTED: similar to hCG1646661 [Homo sapiens] 50 3e-06
gi|7669503 lysosomal-associated membrane protein 2 isoform B pre... 30 3.3
>gi|4502515 carbonic anhydrase XII isoform 1 precursor [Homo
sapiens]
Length = 354
Score = 723 bits (1867), Expect = 0.0
Identities = 354/354 (100%), Positives = 354/354 (100%)
Query: 1 MPRRSLHAAAVLLLVILKEQPSSPAPVNGSKWTYFGPDGENSWSKKYPSCGGLLQSPIDL 60
MPRRSLHAAAVLLLVILKEQPSSPAPVNGSKWTYFGPDGENSWSKKYPSCGGLLQSPIDL
Sbjct: 1 MPRRSLHAAAVLLLVILKEQPSSPAPVNGSKWTYFGPDGENSWSKKYPSCGGLLQSPIDL 60
Query: 61 HSDILQYDASLTPLEFQGYNLSANKQFLLTNNGHSVKLNLPSDMHIQGLQSRYSATQLHL 120
HSDILQYDASLTPLEFQGYNLSANKQFLLTNNGHSVKLNLPSDMHIQGLQSRYSATQLHL
Sbjct: 61 HSDILQYDASLTPLEFQGYNLSANKQFLLTNNGHSVKLNLPSDMHIQGLQSRYSATQLHL 120
Query: 121 HWGNPNDPHGSEHTVSGQHFAAELHIVHYNSDLYPDASTASNKSEGLAVLAVLIEMGSFN 180
HWGNPNDPHGSEHTVSGQHFAAELHIVHYNSDLYPDASTASNKSEGLAVLAVLIEMGSFN
Sbjct: 121 HWGNPNDPHGSEHTVSGQHFAAELHIVHYNSDLYPDASTASNKSEGLAVLAVLIEMGSFN 180
Query: 181 PSYDKIFSHLQHVKYKGQEAFVPGFNIEELLPERTAEYYRYRGSLTTPPCNPTVLWTVFR 240
PSYDKIFSHLQHVKYKGQEAFVPGFNIEELLPERTAEYYRYRGSLTTPPCNPTVLWTVFR
Sbjct: 181 PSYDKIFSHLQHVKYKGQEAFVPGFNIEELLPERTAEYYRYRGSLTTPPCNPTVLWTVFR 240
Query: 241 NPVQISQEQLLALETALYCTHMDDPSPREMINNFRQVQKFDERLVYTSFSQVQVCTAAGL 300
NPVQISQEQLLALETALYCTHMDDPSPREMINNFRQVQKFDERLVYTSFSQVQVCTAAGL
Sbjct: 241 NPVQISQEQLLALETALYCTHMDDPSPREMINNFRQVQKFDERLVYTSFSQVQVCTAAGL 300
Query: 301 SLGIILSLALAGILGICIVVVVSIWLFRRKSIKKGDNKGVIYKPATKMETEAHA 354
SLGIILSLALAGILGICIVVVVSIWLFRRKSIKKGDNKGVIYKPATKMETEAHA
Sbjct: 301 SLGIILSLALAGILGICIVVVVSIWLFRRKSIKKGDNKGVIYKPATKMETEAHA 354
>gi|45935383 carbonic anhydrase XII isoform 2 precursor [Homo
sapiens]
Length = 343
Score = 694 bits (1792), Expect = 0.0
Identities = 343/354 (96%), Positives = 343/354 (96%), Gaps = 11/354 (3%)
Query: 1 MPRRSLHAAAVLLLVILKEQPSSPAPVNGSKWTYFGPDGENSWSKKYPSCGGLLQSPIDL 60
MPRRSLHAAAVLLLVILKEQPSSPAPVNGSKWTYFGPDGENSWSKKYPSCGGLLQSPIDL
Sbjct: 1 MPRRSLHAAAVLLLVILKEQPSSPAPVNGSKWTYFGPDGENSWSKKYPSCGGLLQSPIDL 60
Query: 61 HSDILQYDASLTPLEFQGYNLSANKQFLLTNNGHSVKLNLPSDMHIQGLQSRYSATQLHL 120
HSDILQYDASLTPLEFQGYNLSANKQFLLTNNGHSVKLNLPSDMHIQGLQSRYSATQLHL
Sbjct: 61 HSDILQYDASLTPLEFQGYNLSANKQFLLTNNGHSVKLNLPSDMHIQGLQSRYSATQLHL 120
Query: 121 HWGNPNDPHGSEHTVSGQHFAAELHIVHYNSDLYPDASTASNKSEGLAVLAVLIEMGSFN 180
HWGNPNDPHGSEHTVSGQHFAAELHIVHYNSDLYPDASTASNKSEGLAVLAVLIEMGSFN
Sbjct: 121 HWGNPNDPHGSEHTVSGQHFAAELHIVHYNSDLYPDASTASNKSEGLAVLAVLIEMGSFN 180
Query: 181 PSYDKIFSHLQHVKYKGQEAFVPGFNIEELLPERTAEYYRYRGSLTTPPCNPTVLWTVFR 240
PSYDKIFSHLQHVKYKGQEAFVPGFNIEELLPERTAEYYRYRGSLTTPPCNPTVLWTVFR
Sbjct: 181 PSYDKIFSHLQHVKYKGQEAFVPGFNIEELLPERTAEYYRYRGSLTTPPCNPTVLWTVFR 240
Query: 241 NPVQISQEQLLALETALYCTHMDDPSPREMINNFRQVQKFDERLVYTSFSQVQVCTAAGL 300
NPVQISQEQLLALETALYCTHMDDPSPREMINNFRQVQKFDERLVYTSFSQ
Sbjct: 241 NPVQISQEQLLALETALYCTHMDDPSPREMINNFRQVQKFDERLVYTSFSQ--------- 291
Query: 301 SLGIILSLALAGILGICIVVVVSIWLFRRKSIKKGDNKGVIYKPATKMETEAHA 354
GIILSLALAGILGICIVVVVSIWLFRRKSIKKGDNKGVIYKPATKMETEAHA
Sbjct: 292 --GIILSLALAGILGICIVVVVSIWLFRRKSIKKGDNKGVIYKPATKMETEAHA 343
>gi|6912284 carbonic anhydrase XIV precursor [Homo sapiens]
Length = 337
Score = 267 bits (683), Expect = 9e-72
Identities = 140/326 (42%), Positives = 206/326 (63%), Gaps = 9/326 (2%)
Query: 29 GSKWTYFGPDGENSWSKKYPSCGGLLQSPIDLHSDILQYDASLTPLEFQGYNLSANKQFL 88
G WTY GP G++ W YP CG QSPID+ +D + +D L L+ GY+ +
Sbjct: 19 GQHWTYEGPHGQDHWPASYPECGNNAQSPIDIQTDSVTFDPDLPALQPHGYDQPGTEPLD 78
Query: 89 LTNNGHSVKLNLPSDMHIQGLQSRYSATQLHLHWGNPNDPHGSEHTVSGQHFAAELHIVH 148
L NNGH+V+L+LPS +++ GL +Y A QLHLHWG P GSEH ++ + AELHIVH
Sbjct: 79 LHNNGHTVQLSLPSTLYLGGLPRKYVAAQLHLHWGQKGSPGGSEHQINSEATFAELHIVH 138
Query: 149 YNSDLYPDASTASNKSEGLAVLAVLIEMG-SFNPSYDKIFSHLQHVKYKGQEAFVPGFNI 207
Y+SD Y S A+ + +GLAVL +LIE+G + N +Y+ I SHL V++K Q+ VP FN+
Sbjct: 139 YDSDSYDSLSEAAERPQGLAVLGILIEVGETKNIAYEHILSHLHEVRHKDQKTSVPPFNL 198
Query: 208 EELLPERTAEYYRYRGSLTTPPCNPTVLWTVFRNPVQISQEQLLALETALYCTHMDDPSP 267
ELLP++ +Y+RY GSLTTPPC +VLWTVF QIS EQL L+ L+ T ++PS
Sbjct: 199 RELLPKQLGQYFRYNGSLTTPPCYQSVLWTVFYRRSQISMEQLEKLQGTLFSTE-EEPS- 256
Query: 268 REMINNFRQVQKFDERLVYTSFSQVQVCTAAGLSLGIILSLALAGILGICIVVVVSIWLF 327
+ ++ N+R +Q ++R+V+ SF Q + + G +LSL + GIL C+ ++++++
Sbjct: 257 KLLVQNYRALQPLNQRMVFASFIQ----AGSSYTTGEMLSLGV-GILVGCLCLLLAVYFI 311
Query: 328 RRKSIKKG-DNKGVIYKPATKMETEA 352
RK KK +N+ + + + TEA
Sbjct: 312 ARKIRKKRLENRKSVVFTSAQATTEA 337
>gi|169636420 carbonic anhydrase IX precursor [Homo sapiens]
Length = 459
Score = 201 bits (511), Expect = 8e-52
Identities = 124/338 (36%), Positives = 170/338 (50%), Gaps = 32/338 (9%)
Query: 30 SKWTYFGPDGENSWSKKYPSCGGLLQSPIDLHSDILQYDASLTPLEFQGYNLSANKQFLL 89
S W Y G+ W + P+C G QSP+D+ + + +L PLE G+ L + L
Sbjct: 139 SHWRY---GGDPPWPRVSPACAGRFQSPVDIRPQLAAFCPALRPLELLGFQLPPLPELRL 195
Query: 90 TNNGHSVKLNLPSDMHIQ-GLQSRYSATQLHLHWGNPNDPHGSEHTVSGQHFAAELHIVH 148
NNGHSV+L LP + + G Y A QLHLHWG P GSEHTV G F AE+H+VH
Sbjct: 196 RNNGHSVQLTLPPGLEMALGPGREYRALQLHLHWGAAGRP-GSEHTVEGHRFPAEIHVVH 254
Query: 149 YNSDLYPDASTASNKSEGLAVLAVLIEMG-SFNPSYDKIFSHLQHVKYKGQEAFVPGFNI 207
S + A + GLAVLA +E G N +Y+++ S L+ + +G E VPG +I
Sbjct: 255 L-STAFARVDEALGRPGGLAVLAAFLEEGPEENSAYEQLLSRLEEIAEEGSETQVPGLDI 313
Query: 208 EELLPERTAEYYRYRGSLTTPPCNPTVLWTVFRNPVQISQEQLLALETALYCTHMDDPSP 267
LLP + Y++Y GSLTTPPC V+WTVF V +S +QL L L+ P
Sbjct: 314 SALLPSDFSRYFQYEGSLTTPPCAQGVIWTVFNQTVMLSAKQLHTLSDTLW-----GPGD 368
Query: 268 REMINNFRQVQKFDERLVYTSFS-------------QVQVCTAAGLSLGIILSLALAGIL 314
+ NFR Q + R++ SF Q+ C AAG L ++ L A
Sbjct: 369 SRLQLNFRATQPLNGRVIEASFPAGVDSSPRAAEPVQLNSCLAAGDILALVFGLLFA--- 425
Query: 315 GICIVVVVSIWLFRRKSIKKGDNKGVIYKPATKMETEA 352
V V+ + R+ ++G GV Y+PA ET A
Sbjct: 426 ----VTSVAFLVQMRRQHRRGTKGGVSYRPAEVAETGA 459
>gi|70167127 carbonic anhydrase VI precursor [Homo sapiens]
Length = 308
Score = 186 bits (473), Expect = 2e-47
Identities = 104/265 (39%), Positives = 149/265 (56%), Gaps = 12/265 (4%)
Query: 30 SKWTYF-GPDGENSWSKKYPSCGGLLQSPIDLHSDILQYDASLTPLEFQGYNLSANKQFL 88
S WTY G E W + YP+CGG QSPI+L ++Y+ SL L GY A +F
Sbjct: 21 SDWTYSEGALDEAHWPQHYPACGGQRQSPINLQRTKVRYNPSLKGLNMTGYETQAG-EFP 79
Query: 89 LTNNGHSVKLNLPSDMHIQGLQSR-YSATQLHLHWGNPNDP-HGSEHTVSGQHFAAELHI 146
+ NNGH+V+++LPS M + Y A Q+H HWG + GSEHTV G E+HI
Sbjct: 80 MVNNGHTVQISLPSTMRMTVADGTVYIAQQMHFHWGGASSEISGSEHTVDGIRHVIEIHI 139
Query: 147 VHYNSDLYPDASTASNKSEGLAVLAVLIEMGSF--NPSYDKIFSHLQHVKYKGQEAFVPG 204
VHYNS Y A + +GLAVLA +E+ ++ N Y SHL ++KY GQ + G
Sbjct: 140 VHYNSK-YKSYDIAQDAPDGLAVLAAFVEVKNYPENTYYSNFISHLANIKYPGQRTTLTG 198
Query: 205 FNIEELLPERTAEYYRYRGSLTTPPCNPTVLWTVFRNPVQISQEQLLALETALYCTHMDD 264
+++++LP YY Y GSLTTPPC V W V + V++S+ Q+ LE +L D
Sbjct: 199 LDVQDMLPRNLQHYYTYHGSLTTPPCTENVHWFVLADFVKLSRTQVWKLENSLL-----D 253
Query: 265 PSPREMINNFRQVQKFDERLVYTSF 289
+ + N++R+ Q + R+V ++F
Sbjct: 254 HRNKTIHNDYRRTQPLNHRVVESNF 278
>gi|4885101 carbonic anhydrase VII isoform 1 [Homo sapiens]
Length = 264
Score = 168 bits (426), Expect = 6e-42
Identities = 103/263 (39%), Positives = 145/263 (55%), Gaps = 12/263 (4%)
Query: 32 WTYFGPDGENSWSKKYPSCGGLLQSPIDLHSDILQYDASLTPLEFQGYNLSANKQFLLTN 91
W Y DG + W K YP G QSPI++ S Y SL PLE + A +TN
Sbjct: 7 WGYGQDDGPSHWHKLYPIAQGDRQSPINIISSQAVYSPSLQPLEL---SYEACMSLSITN 63
Query: 92 NGHSVKLNL-PSDMH--IQG--LQSRYSATQLHLHWGNPNDPHGSEHTVSGQHFAAELHI 146
NGHSV+++ SD + G L+ Y Q H HWG +D GSEHTV G+ F +ELH+
Sbjct: 64 NGHSVQVDFNDSDDRTVVTGGPLEGPYRLKQFHFHWGKKHDV-GSEHTVDGKSFPSELHL 122
Query: 147 VHYNSDLYPDASTASNKSEGLAVLAVLIEMGSFNPSYDKIFSHLQHVKYKGQEAFVPGFN 206
VH+N+ Y A++ +GLAV+ V +E G +PS +++ L V++KG +A FN
Sbjct: 123 VHWNAKKYSTFGEAASAPDGLAVVGVFLETGDEHPSMNRLTDALYMVRFKGTKAQFSCFN 182
Query: 207 IEELLPERTAEYYRYRGSLTTPPCNPTVLWTVFRNPVQISQEQLLALETALYCTHMDDPS 266
+ LLP + Y+ Y GSLTTPP + +V W V R P+ IS+ Q+ + L+ + +D
Sbjct: 183 PKCLLP-ASRHYWTYPGSLTTPPLSESVTWIVLREPICISERQMGKFRSLLFTS--EDDE 239
Query: 267 PREMINNFRQVQKFDERLVYTSF 289
M+NNFR Q R+V SF
Sbjct: 240 RIHMVNNFRPPQPLKGRVVKASF 262
>gi|192447434 carbonic anhydrase I [Homo sapiens]
Length = 261
Score = 164 bits (415), Expect = 1e-40
Identities = 95/263 (36%), Positives = 140/263 (53%), Gaps = 12/263 (4%)
Query: 32 WTYFGPDGENSWSKKYPSCGGLLQSPIDLHSDILQYDASLTPLEFQGYNLSANKQFLLTN 91
W Y +G WSK YP G QSP+D+ + ++D SL P+ YN + K+ + N
Sbjct: 6 WGYDDKNGPEQWSKLYPIANGNNQSPVDIKTSETKHDTSLKPISVS-YNPATAKEII--N 62
Query: 92 NGHSVKLNLPSDMHIQGLQS-----RYSATQLHLHWGNPNDPHGSEHTVSGQHFAAELHI 146
GHS +N + + L+ Y Q H HWG+ N+ HGSEHTV G ++AELH+
Sbjct: 63 VGHSFHVNFEDNDNRSVLKGGPFSDSYRLFQFHFHWGSTNE-HGSEHTVDGVKYSAELHV 121
Query: 147 VHYNSDLYPDASTASNKSEGLAVLAVLIEMGSFNPSYDKIFSHLQHVKYKGQEAFVPGFN 206
H+NS Y + A++K++GLAV+ VL+++G NP K+ LQ +K KG+ A F+
Sbjct: 122 AHWNSAKYSSLAEAASKADGLAVIGVLMKVGEANPKLQKVLDALQAIKTKGKRAPFTNFD 181
Query: 207 IEELLPERTAEYYRYRGSLTTPPCNPTVLWTVFRNPVQISQEQLLALETALYCTHMDDPS 266
LLP + +++ Y GSLT PP +V W + + + +S EQL + L D+
Sbjct: 182 PSTLLPS-SLDFWTYPGSLTHPPLYESVTWIICKESISVSSEQLAQFRSLLSNVEGDNAV 240
Query: 267 PREMINNFRQVQKFDERLVYTSF 289
P M +N R Q R V SF
Sbjct: 241 P--MQHNNRPTQPLKGRTVRASF 261
>gi|192447432 carbonic anhydrase I [Homo sapiens]
Length = 261
Score = 164 bits (415), Expect = 1e-40
Identities = 95/263 (36%), Positives = 140/263 (53%), Gaps = 12/263 (4%)
Query: 32 WTYFGPDGENSWSKKYPSCGGLLQSPIDLHSDILQYDASLTPLEFQGYNLSANKQFLLTN 91
W Y +G WSK YP G QSP+D+ + ++D SL P+ YN + K+ + N
Sbjct: 6 WGYDDKNGPEQWSKLYPIANGNNQSPVDIKTSETKHDTSLKPISVS-YNPATAKEII--N 62
Query: 92 NGHSVKLNLPSDMHIQGLQS-----RYSATQLHLHWGNPNDPHGSEHTVSGQHFAAELHI 146
GHS +N + + L+ Y Q H HWG+ N+ HGSEHTV G ++AELH+
Sbjct: 63 VGHSFHVNFEDNDNRSVLKGGPFSDSYRLFQFHFHWGSTNE-HGSEHTVDGVKYSAELHV 121
Query: 147 VHYNSDLYPDASTASNKSEGLAVLAVLIEMGSFNPSYDKIFSHLQHVKYKGQEAFVPGFN 206
H+NS Y + A++K++GLAV+ VL+++G NP K+ LQ +K KG+ A F+
Sbjct: 122 AHWNSAKYSSLAEAASKADGLAVIGVLMKVGEANPKLQKVLDALQAIKTKGKRAPFTNFD 181
Query: 207 IEELLPERTAEYYRYRGSLTTPPCNPTVLWTVFRNPVQISQEQLLALETALYCTHMDDPS 266
LLP + +++ Y GSLT PP +V W + + + +S EQL + L D+
Sbjct: 182 PSTLLPS-SLDFWTYPGSLTHPPLYESVTWIICKESISVSSEQLAQFRSLLSNVEGDNAV 240
Query: 267 PREMINNFRQVQKFDERLVYTSF 289
P M +N R Q R V SF
Sbjct: 241 P--MQHNNRPTQPLKGRTVRASF 261
>gi|192447430 carbonic anhydrase I [Homo sapiens]
Length = 261
Score = 164 bits (415), Expect = 1e-40
Identities = 95/263 (36%), Positives = 140/263 (53%), Gaps = 12/263 (4%)
Query: 32 WTYFGPDGENSWSKKYPSCGGLLQSPIDLHSDILQYDASLTPLEFQGYNLSANKQFLLTN 91
W Y +G WSK YP G QSP+D+ + ++D SL P+ YN + K+ + N
Sbjct: 6 WGYDDKNGPEQWSKLYPIANGNNQSPVDIKTSETKHDTSLKPISVS-YNPATAKEII--N 62
Query: 92 NGHSVKLNLPSDMHIQGLQS-----RYSATQLHLHWGNPNDPHGSEHTVSGQHFAAELHI 146
GHS +N + + L+ Y Q H HWG+ N+ HGSEHTV G ++AELH+
Sbjct: 63 VGHSFHVNFEDNDNRSVLKGGPFSDSYRLFQFHFHWGSTNE-HGSEHTVDGVKYSAELHV 121
Query: 147 VHYNSDLYPDASTASNKSEGLAVLAVLIEMGSFNPSYDKIFSHLQHVKYKGQEAFVPGFN 206
H+NS Y + A++K++GLAV+ VL+++G NP K+ LQ +K KG+ A F+
Sbjct: 122 AHWNSAKYSSLAEAASKADGLAVIGVLMKVGEANPKLQKVLDALQAIKTKGKRAPFTNFD 181
Query: 207 IEELLPERTAEYYRYRGSLTTPPCNPTVLWTVFRNPVQISQEQLLALETALYCTHMDDPS 266
LLP + +++ Y GSLT PP +V W + + + +S EQL + L D+
Sbjct: 182 PSTLLPS-SLDFWTYPGSLTHPPLYESVTWIICKESISVSSEQLAQFRSLLSNVEGDNAV 240
Query: 267 PREMINNFRQVQKFDERLVYTSF 289
P M +N R Q R V SF
Sbjct: 241 P--MQHNNRPTQPLKGRTVRASF 261
>gi|4502517 carbonic anhydrase I [Homo sapiens]
Length = 261
Score = 164 bits (415), Expect = 1e-40
Identities = 95/263 (36%), Positives = 140/263 (53%), Gaps = 12/263 (4%)
Query: 32 WTYFGPDGENSWSKKYPSCGGLLQSPIDLHSDILQYDASLTPLEFQGYNLSANKQFLLTN 91
W Y +G WSK YP G QSP+D+ + ++D SL P+ YN + K+ + N
Sbjct: 6 WGYDDKNGPEQWSKLYPIANGNNQSPVDIKTSETKHDTSLKPISVS-YNPATAKEII--N 62
Query: 92 NGHSVKLNLPSDMHIQGLQS-----RYSATQLHLHWGNPNDPHGSEHTVSGQHFAAELHI 146
GHS +N + + L+ Y Q H HWG+ N+ HGSEHTV G ++AELH+
Sbjct: 63 VGHSFHVNFEDNDNRSVLKGGPFSDSYRLFQFHFHWGSTNE-HGSEHTVDGVKYSAELHV 121
Query: 147 VHYNSDLYPDASTASNKSEGLAVLAVLIEMGSFNPSYDKIFSHLQHVKYKGQEAFVPGFN 206
H+NS Y + A++K++GLAV+ VL+++G NP K+ LQ +K KG+ A F+
Sbjct: 122 AHWNSAKYSSLAEAASKADGLAVIGVLMKVGEANPKLQKVLDALQAIKTKGKRAPFTNFD 181
Query: 207 IEELLPERTAEYYRYRGSLTTPPCNPTVLWTVFRNPVQISQEQLLALETALYCTHMDDPS 266
LLP + +++ Y GSLT PP +V W + + + +S EQL + L D+
Sbjct: 182 PSTLLPS-SLDFWTYPGSLTHPPLYESVTWIICKESISVSSEQLAQFRSLLSNVEGDNAV 240
Query: 267 PREMINNFRQVQKFDERLVYTSF 289
P M +N R Q R V SF
Sbjct: 241 P--MQHNNRPTQPLKGRTVRASF 261
>gi|38348436 carbonic anhydrase XIII [Homo sapiens]
Length = 262
Score = 162 bits (411), Expect = 3e-40
Identities = 98/263 (37%), Positives = 150/263 (57%), Gaps = 12/263 (4%)
Query: 32 WTYFGPDGENSWSKKYPSCGGLLQSPIDLHSDILQYDASLTPLEFQGYNLSANKQFLLTN 91
W Y +G W + +P G QSPI++ + ++YD+SL PL + Y+ S+ K +++N
Sbjct: 6 WGYREHNGPIHWKEFFPIADGDQQSPIEIKTKEVKYDSSLRPLSIK-YDPSSAK--IISN 62
Query: 92 NGHSVKLNLPSDMH---IQG--LQSRYSATQLHLHWGNPNDPHGSEHTVSGQHFAAELHI 146
+GHS ++ + ++G L Y Q+HLHWG+ +D HGSEH V G +AAELH+
Sbjct: 63 SGHSFNVDFDDTENKSVLRGGPLTGSYRLRQVHLHWGSADD-HGSEHIVDGVSYAAELHV 121
Query: 147 VHYNSDLYPDASTASNKSEGLAVLAVLIEMGSFNPSYDKIFSHLQHVKYKGQEAFVPGFN 206
VH+NSD YP A+++ +GLAVL V +++G N KI L +K KG++ F+
Sbjct: 122 VHWNSDKYPSFVEAAHEPDGLAVLGVFLQIGEPNSQLQKITDTLDSIKEKGKQTRFTNFD 181
Query: 207 IEELLPERTAEYYRYRGSLTTPPCNPTVLWTVFRNPVQISQEQLLALETALYCTHMDDPS 266
+ LLP + +Y+ Y GSLT PP +V W V + P+ IS +Q LA +L CT + +
Sbjct: 182 LLSLLPP-SWDYWTYPGSLTVPPLLESVTWIVLKQPINISSQQ-LAKFRSLLCT-AEGEA 238
Query: 267 PREMINNFRQVQKFDERLVYTSF 289
+++N R Q R V SF
Sbjct: 239 AAFLVSNHRPPQPLKGRKVRASF 261
>gi|91208428 protein tyrosine phosphatase, receptor-type, zeta1
precursor [Homo sapiens]
Length = 2315
Score = 158 bits (399), Expect = 8e-39
Identities = 91/269 (33%), Positives = 148/269 (55%), Gaps = 15/269 (5%)
Query: 32 WTYFGPDGENSWSKKYPSCGGLLQSPIDLHSDILQYDASLTPLEFQGYNLSANKQFLLTN 91
W+Y G + +W KKYP+C QSPI++ D+ Q + +L L+FQG++ ++ + + N
Sbjct: 38 WSYTGALNQKNWGKKYPTCNSPKQSPINIDEDLTQVNVNLKKLKFQGWDKTSLENTFIHN 97
Query: 92 NGHSVKLNLPSDMHIQGLQSR--YSATQLHLHWGNPN-DPHGSEHTVSGQHFAAELHIVH 148
G +V++NL +D + G S + A+++ HWG N GSEH++ GQ F E+ I
Sbjct: 98 TGKTVEINLTNDYRVSGGVSEMVFKASKITFHWGKCNMSSDGSEHSLEGQKFPLEMQIYC 157
Query: 149 YNSDLYPDASTASNKSEGLAVLAVLIEMGS-FNPSYDKIFSHLQHVKYKGQEAFVPGFNI 207
+++D + A L L++L E+G+ N + I ++ V G++A + F +
Sbjct: 158 FDADRFSSFEEAVKGKGKLRALSILFEVGTEENLDFKAIIDGVESVSRFGKQAALDPFIL 217
Query: 208 EELLPERTAEYYRYRGSLTTPPCNPTVLWTVFRNPVQISQEQL------LALETALYCTH 261
LLP T +YY Y GSLT+PPC TV W VF++ V IS+ QL L ++ + Y
Sbjct: 218 LNLLPNSTDKYYIYNGSLTSPPCTDTVDWIVFKDTVSISESQLAVFCEVLTMQQSGYVML 277
Query: 262 MDDPSPREMINNFRQVQKFDERLVYTSFS 290
MD + NNFR+ Q R V++S++
Sbjct: 278 MD-----YLQNNFREQQYKFSRQVFSSYT 301
>gi|194097398 protein tyrosine phosphatase, receptor type, G
precursor [Homo sapiens]
Length = 1445
Score = 157 bits (398), Expect = 1e-38
Identities = 89/262 (33%), Positives = 134/262 (51%), Gaps = 6/262 (2%)
Query: 32 WTYFGPDGENSWSKKYPSCGGLLQSPIDLHSDILQYDASLTPLEFQGYNLSANKQFLLTN 91
W Y G G W SCGG QSPID+ + L+ G++ ++ + + N
Sbjct: 60 WAYSGAYGPEHWVTSSVSCGGRHQSPIDILDQYARVGEEYQELQLDGFDNESSNKTWMKN 119
Query: 92 NGHSVKLNLPSDMHIQG--LQSRYSATQLHLHWGNPNDPHGSEHTVSGQHFAAELHIVHY 149
G +V + L D + G L R+ A ++ HWG+ N GSEH+++G+ F E+ I Y
Sbjct: 120 TGKTVAILLKDDYFVSGAGLPGRFKAEKVEFHWGHSNGSAGSEHSINGRRFPVEMQIFFY 179
Query: 150 NSDLYPDASTASNKSEGLAVLAVLIEMGSF-NPSYDKIFSHLQHVKYKGQEAFVPGFNIE 208
N D + TA +++ + +A+ ++ N + D I L+ V + +E F+ F +
Sbjct: 180 NPDDFDSFQTAISENRIIGAMAIFFQVSPRDNSALDPIIHGLKGVVHHEKETFLDPFVLR 239
Query: 209 ELLPERTAEYYRYRGSLTTPPCNPTVLWTVFRNPVQISQEQLLALETALYCTHMDD--PS 266
+LLP YYRY GSLTTPPC+ V W VFR PV IS QL A +++ T D S
Sbjct: 240 DLLPASLGSYYRYTGSLTTPPCSEIVEWIVFRRPVPISYHQLEAF-YSIFTTEQQDHVKS 298
Query: 267 PREMINNFRQVQKFDERLVYTS 288
+ NNFR Q+ +R+V S
Sbjct: 299 VEYLRNNFRPQQRLHDRVVSKS 320
>gi|4557395 carbonic anhydrase II [Homo sapiens]
Length = 260
Score = 154 bits (389), Expect = 1e-37
Identities = 94/264 (35%), Positives = 137/264 (51%), Gaps = 15/264 (5%)
Query: 32 WTYFGPDGENSWSKKYPSCGGLLQSPIDLHSDILQYDASLTPLEFQGYNLSANKQFLLTN 91
W Y +G W K +P G QSP+D+ + +YD SL PL Y+ + + + L N
Sbjct: 5 WGYGKHNGPEHWHKDFPIAKGERQSPVDIDTHTAKYDPSLKPLSVS-YDQATSLRIL--N 61
Query: 92 NGHSVKLNLPSDMH---IQG--LQSRYSATQLHLHWGNPNDPHGSEHTVSGQHFAAELHI 146
NGH+ + ++G L Y Q H HWG+ D GSEHTV + +AAELH+
Sbjct: 62 NGHAFNVEFDDSQDKAVLKGGPLDGTYRLIQFHFHWGSL-DGQGSEHTVDKKKYAAELHL 120
Query: 147 VHYNSDLYPDASTASNKSEGLAVLAVLIEMGSFNPSYDKIFSHLQHVKYKGQEAFVPGFN 206
VH+N+ Y D A + +GLAVL + +++GS P K+ L +K KG+ A F+
Sbjct: 121 VHWNTK-YGDFGKAVQQPDGLAVLGIFLKVGSAKPGLQKVVDVLDSIKTKGKSADFTNFD 179
Query: 207 IEELLPERTAEYYRYRGSLTTPPCNPTVLWTVFRNPVQISQEQLLALETALYCTHMDDPS 266
LLPE + +Y+ Y GSLTTPP V W V + P+ +S EQ+L + +
Sbjct: 180 PRGLLPE-SLDYWTYPGSLTTPPLLECVTWIVLKEPISVSSEQVLKFRKLNF---NGEGE 235
Query: 267 PRE-MINNFRQVQKFDERLVYTSF 289
P E M++N+R Q R + SF
Sbjct: 236 PEELMVDNWRPAQPLKNRQIKASF 259
>gi|4885099 carbonic anhydrase III [Homo sapiens]
Length = 260
Score = 150 bits (380), Expect = 1e-36
Identities = 87/264 (32%), Positives = 142/264 (53%), Gaps = 13/264 (4%)
Query: 31 KWTYFGPDGENSWSKKYPSCGGLLQSPIDLHSDILQYDASLTPLEFQGYNLSANKQFLLT 90
+W Y +G + W + +P+ G QSP++LH+ +++D SL P Y+ + K L
Sbjct: 4 EWGYASHNGPDHWHELFPNAKGENQSPVELHTKDIRHDPSLQPWSVS-YDGGSAKTIL-- 60
Query: 91 NNGHSVKLNLPSDMH---IQG--LQSRYSATQLHLHWGNPNDPHGSEHTVSGQHFAAELH 145
NNG + ++ ++G L Y Q HLHWG+ +D HGSEHTV G +AAELH
Sbjct: 61 NNGKTCRVVFDDTYDRSMLRGGPLPGPYRLRQFHLHWGSSDD-HGSEHTVDGVKYAAELH 119
Query: 146 IVHYNSDLYPDASTASNKSEGLAVLAVLIEMGSFNPSYDKIFSHLQHVKYKGQEAFVPGF 205
+VH+N Y A + +G+AV+ + +++G N + L +K KG+EA F
Sbjct: 120 LVHWNPK-YNTFKEALKQRDGIAVIGIFLKIGHENGEFQIFLDALDKIKTKGKEAPFTKF 178
Query: 206 NIEELLPERTAEYYRYRGSLTTPPCNPTVLWTVFRNPVQISQEQLLALETALYCTHMDDP 265
+ L P +Y+ Y+GS TTPPC ++W + + P+ +S +Q+ L + L + P
Sbjct: 179 DPSCLFPA-CRDYWTYQGSFTTPPCEECIVWLLLKEPMTVSSDQMAKLRSLLSSAENEPP 237
Query: 266 SPREMINNFRQVQKFDERLVYTSF 289
P +++N+R Q + R+V SF
Sbjct: 238 VP--LVSNWRPPQPINNRVVRASF 259
>gi|22027500 carbonic anhydrase VIII [Homo sapiens]
Length = 290
Score = 142 bits (358), Expect = 5e-34
Identities = 85/269 (31%), Positives = 138/269 (51%), Gaps = 13/269 (4%)
Query: 29 GSKWTYFGPDGENSWSKKYPSCGGLLQSPIDLHSDILQYDASLTPLEFQGYNLSANKQFL 88
G +W Y + W +P G QSPI+L+S +YD SL + N +
Sbjct: 26 GVEWGY---EEGVEWGLVFPDANGEYQSPINLNSREARYDPSLLDVRLSP-NYVVCRDCE 81
Query: 89 LTNNGHSVKLNLPSDMHIQG----LQSRYSATQLHLHWGNPNDPHGSEHTVSGQHFAAEL 144
+TN+GH++++ L S + G + ++ HWG N GSEHTV+ + F EL
Sbjct: 82 VTNDGHTIQVILKSKSVLSGGPLPQGHEFELYEVRFHWGRENQ-RGSEHTVNFKAFPMEL 140
Query: 145 HIVHYNSDLYPDASTASNKSEGLAVLAVLIEMGSFNPSYDKIFSHLQHVKYKGQEAFVPG 204
H++H+NS L+ A K G+A++A+ +++G + + LQ ++YKG+ +P
Sbjct: 141 HLIHWNSTLFGSIDEAVGKPHGIAIIALFVQIGKEHVGLKAVTEILQDIQYKGKSKTIPC 200
Query: 205 FNIEELLPE-RTAEYYRYRGSLTTPPCNPTVLWTVFRNPVQISQ---EQLLALETALYCT 260
FN LLP+ +Y+ Y GSLT PPC+ V W +FR P+ ISQ E+ L T +
Sbjct: 201 FNPNTLLPDPLLRDYWVYEGSLTIPPCSEGVTWILFRYPLTISQLQIEEFRRLRTHVKGA 260
Query: 261 HMDDPSPREMINNFRQVQKFDERLVYTSF 289
+ + + +NFR Q +R++ +F
Sbjct: 261 ELVEGCDGILGDNFRPTQPLSDRVIRAAF 289
>gi|4502519 carbonic anhydrase IV precursor [Homo sapiens]
Length = 312
Score = 141 bits (356), Expect = 8e-34
Identities = 104/316 (32%), Positives = 160/316 (50%), Gaps = 20/316 (6%)
Query: 12 LLLVILKEQPSSPAPVNGSKWTYFGPDGENSWSKKYP-----SCGGLLQSPIDLHSDILQ 66
+LL +L + P+ S W Y +++ P +C QSPI++ + +
Sbjct: 3 MLLALLALSAARPSASAESHWCYEVQAESSNYPCLVPVKWGGNCQKDRQSPINIVTTKAK 62
Query: 67 YDASLTPLEFQGYNLSANKQFLLTNNGHSVKLNLPSDMHIQG--LQSRYSATQLHLHWGN 124
D L F GY+ + + + NNGHSV + L + I G L + Y A QLHLHW +
Sbjct: 63 VDKKLGRFFFSGYD--KKQTWTVQNNGHSVMMLLENKASISGGGLPAPYQAKQLHLHWSD 120
Query: 125 PNDPH-GSEHTVSGQHFAAELHIVHYNSD-LYPDASTASNKSEGLAVLAVLIEMGS-FNP 181
P+ GSEH++ G+HFA E+HIVH + A + + +AVLA L+E G+ N
Sbjct: 121 L--PYKGSEHSLDGEHFAMEMHIVHEKEKGTSRNVKEAQDPEDEIAVLAFLVEAGTQVNE 178
Query: 182 SYDKIFSHLQHVKYKGQEAFVPGFNIEELLP--ERTAEYYRYRGSLTTPPCNPTVLWTVF 239
+ + L ++ + ++ +LLP E+ Y+RY GSLTTP C+ V+WTVF
Sbjct: 179 GFQPLVEALSNIPKPEMSTTMAESSLLDLLPKEEKLRHYFRYLGSLTTPTCDEKVVWTVF 238
Query: 240 RNPVQISQEQLLALETALYCTHMDDPSPREMINNFRQVQKFDERLVYTSFSQVQ-VCTAA 298
R P+Q+ +EQ+LA LY D M +N R +Q+ +R V S + + + A
Sbjct: 239 REPIQLHREQILAFSQKLY---YDKEQTVSMKDNVRPLQQLGQRTVIKSGAPGRPLPWAL 295
Query: 299 GLSLGIILSLALAGIL 314
LG +L+ LAG L
Sbjct: 296 PALLGPMLACLLAGFL 311
>gi|62240989 carbonic anhydrase VII isoform 2 [Homo sapiens]
Length = 208
Score = 139 bits (351), Expect = 3e-33
Identities = 82/206 (39%), Positives = 120/206 (58%), Gaps = 9/206 (4%)
Query: 89 LTNNGHSVKLNL-PSDMH--IQG--LQSRYSATQLHLHWGNPNDPHGSEHTVSGQHFAAE 143
+TNNGHSV+++ SD + G L+ Y Q H HWG +D GSEHTV G+ F +E
Sbjct: 5 ITNNGHSVQVDFNDSDDRTVVTGGPLEGPYRLKQFHFHWGKKHDV-GSEHTVDGKSFPSE 63
Query: 144 LHIVHYNSDLYPDASTASNKSEGLAVLAVLIEMGSFNPSYDKIFSHLQHVKYKGQEAFVP 203
LH+VH+N+ Y A++ +GLAV+ V +E G +PS +++ L V++KG +A
Sbjct: 64 LHLVHWNAKKYSTFGEAASAPDGLAVVGVFLETGDEHPSMNRLTDALYMVRFKGTKAQFS 123
Query: 204 GFNIEELLPERTAEYYRYRGSLTTPPCNPTVLWTVFRNPVQISQEQLLALETALYCTHMD 263
FN + LLP + Y+ Y GSLTTPP + +V W V R P+ IS+ Q+ + L+ + +
Sbjct: 124 CFNPKCLLP-ASRHYWTYPGSLTTPPLSESVTWIVLREPICISERQMGKFRSLLFTS--E 180
Query: 264 DPSPREMINNFRQVQKFDERLVYTSF 289
D M+NNFR Q R+V SF
Sbjct: 181 DDERIHMVNNFRPPQPLKGRVVKASF 206
>gi|4502521 carbonic anhydrase VA, mitochondrial precursor [Homo
sapiens]
Length = 305
Score = 134 bits (337), Expect = 1e-31
Identities = 82/252 (32%), Positives = 126/252 (50%), Gaps = 12/252 (4%)
Query: 43 WSKKYPSCGGLLQSPIDLHSDILQYDASLTPLEFQGYNLSANKQFLLTNNGHSVKLNLPS 102
W+ GG QSPI++ YD L PL + A + N G+ ++
Sbjct: 52 WTVPVSVPGGTRQSPINIQWRDSVYDPQLKPLRV---SYEAASCLYIWNTGYLFQVEFDD 108
Query: 103 DMHIQG-----LQSRYSATQLHLHWGNPNDPHGSEHTVSGQHFAAELHIVHYNSDLYPDA 157
G L++ Y Q H HWG N+ GSEHTV G + AELH+VH+NS Y +
Sbjct: 109 ATEASGISGGPLENHYRLKQFHFHWGAVNEG-GSEHTVDGHAYPAELHLVHWNSVKYQNY 167
Query: 158 STASNKSEGLAVLAVLIEMGSFNPSYDKIFSHLQHVKYKGQEAFVPGFNIEELLPERTAE 217
A GLAV+ V +++G+ + + ++ L +K+K A + F+ LLP +
Sbjct: 168 KEAVVGENGLAVIGVFLKLGAHHQTLQRLVDILPEIKHKDARAAMRPFDPSTLLP-TCWD 226
Query: 218 YYRYRGSLTTPPCNPTVLWTVFRNPVQISQEQLLALETALYCTHMDDPSPREMINNFRQV 277
Y+ Y GSLTTPP +V W + + PV+++ QL A T L+ ++ + M+NN+R +
Sbjct: 227 YWTYAGSLTTPPLTESVTWIIQKEPVEVAPSQLSAFRTLLFSALGEE--EKMMVNNYRPL 284
Query: 278 QKFDERLVYTSF 289
Q R V+ SF
Sbjct: 285 QPLMNRKVWASF 296
>gi|130979954 carbonic anhydrase X [Homo sapiens]
Length = 328
Score = 124 bits (310), Expect = 2e-28
Identities = 79/248 (31%), Positives = 130/248 (52%), Gaps = 17/248 (6%)
Query: 52 GLLQSPIDLHSDILQYDASLTPLEFQ--GYNLSANKQFLLTNNGHSVKLNLPSD--MHIQ 107
G QSP+++ + + +D LTPL G +S + N G V L L + ++I
Sbjct: 63 GKRQSPVNIETSHMIFDPFLTPLRINTGGRKVSGT----MYNTGRHVSLRLDKEHLVNIS 118
Query: 108 GLQSRYS--ATQLHLHWGNPNDPHGSEHTVSGQHFAAELHIVHYNSDLYPDASTASNKSE 165
G YS ++ LH+G+ D GSEH ++GQ F+ E+ ++HYN +LY + + A+
Sbjct: 119 GGPMTYSHRLEEIRLHFGS-EDSQGSEHLLNGQAFSGEVQLIHYNHELYTNVTEAAKSPN 177
Query: 166 GLAVLAVLIEMG-SFNPSYDKIFSH--LQHVKYKGQEAFVPGFNIEELLPERTAEYYRYR 222
GL V+++ I++ S NP +++ + + + YK + G NIEEL PE T+ + Y
Sbjct: 178 GLVVVSIFIKVSDSSNPFLNRMLNRDTITRITYKNDAYLLQGLNIEELYPE-TSSFITYD 236
Query: 223 GSLTTPPCNPTVLWTVFRNPVQISQEQLLALETALYCTHMDDPSPREMINNFRQVQKFDE 282
GS+T PPC T W + PV I++ Q+ +L L + M +NFR VQ +
Sbjct: 237 GSMTIPPCYETASWIIMNKPVYITRMQMHSLR--LLSQNQPSQIFLSMSDNFRPVQPLNN 294
Query: 283 RLVYTSFS 290
R + T+ +
Sbjct: 295 RCIRTNIN 302
>gi|130979679 carbonic anhydrase X [Homo sapiens]
Length = 328
Score = 124 bits (310), Expect = 2e-28
Identities = 79/248 (31%), Positives = 130/248 (52%), Gaps = 17/248 (6%)
Query: 52 GLLQSPIDLHSDILQYDASLTPLEFQ--GYNLSANKQFLLTNNGHSVKLNLPSD--MHIQ 107
G QSP+++ + + +D LTPL G +S + N G V L L + ++I
Sbjct: 63 GKRQSPVNIETSHMIFDPFLTPLRINTGGRKVSGT----MYNTGRHVSLRLDKEHLVNIS 118
Query: 108 GLQSRYS--ATQLHLHWGNPNDPHGSEHTVSGQHFAAELHIVHYNSDLYPDASTASNKSE 165
G YS ++ LH+G+ D GSEH ++GQ F+ E+ ++HYN +LY + + A+
Sbjct: 119 GGPMTYSHRLEEIRLHFGS-EDSQGSEHLLNGQAFSGEVQLIHYNHELYTNVTEAAKSPN 177
Query: 166 GLAVLAVLIEMG-SFNPSYDKIFSH--LQHVKYKGQEAFVPGFNIEELLPERTAEYYRYR 222
GL V+++ I++ S NP +++ + + + YK + G NIEEL PE T+ + Y
Sbjct: 178 GLVVVSIFIKVSDSSNPFLNRMLNRDTITRITYKNDAYLLQGLNIEELYPE-TSSFITYD 236
Query: 223 GSLTTPPCNPTVLWTVFRNPVQISQEQLLALETALYCTHMDDPSPREMINNFRQVQKFDE 282
GS+T PPC T W + PV I++ Q+ +L L + M +NFR VQ +
Sbjct: 237 GSMTIPPCYETASWIIMNKPVYITRMQMHSLR--LLSQNQPSQIFLSMSDNFRPVQPLNN 294
Query: 283 RLVYTSFS 290
R + T+ +
Sbjct: 295 RCIRTNIN 302
>gi|9910366 carbonic anhydrase X [Homo sapiens]
Length = 328
Score = 124 bits (310), Expect = 2e-28
Identities = 79/248 (31%), Positives = 130/248 (52%), Gaps = 17/248 (6%)
Query: 52 GLLQSPIDLHSDILQYDASLTPLEFQ--GYNLSANKQFLLTNNGHSVKLNLPSD--MHIQ 107
G QSP+++ + + +D LTPL G +S + N G V L L + ++I
Sbjct: 63 GKRQSPVNIETSHMIFDPFLTPLRINTGGRKVSGT----MYNTGRHVSLRLDKEHLVNIS 118
Query: 108 GLQSRYS--ATQLHLHWGNPNDPHGSEHTVSGQHFAAELHIVHYNSDLYPDASTASNKSE 165
G YS ++ LH+G+ D GSEH ++GQ F+ E+ ++HYN +LY + + A+
Sbjct: 119 GGPMTYSHRLEEIRLHFGS-EDSQGSEHLLNGQAFSGEVQLIHYNHELYTNVTEAAKSPN 177
Query: 166 GLAVLAVLIEMG-SFNPSYDKIFSH--LQHVKYKGQEAFVPGFNIEELLPERTAEYYRYR 222
GL V+++ I++ S NP +++ + + + YK + G NIEEL PE T+ + Y
Sbjct: 178 GLVVVSIFIKVSDSSNPFLNRMLNRDTITRITYKNDAYLLQGLNIEELYPE-TSSFITYD 236
Query: 223 GSLTTPPCNPTVLWTVFRNPVQISQEQLLALETALYCTHMDDPSPREMINNFRQVQKFDE 282
GS+T PPC T W + PV I++ Q+ +L L + M +NFR VQ +
Sbjct: 237 GSMTIPPCYETASWIIMNKPVYITRMQMHSLR--LLSQNQPSQIFLSMSDNFRPVQPLNN 294
Query: 283 RLVYTSFS 290
R + T+ +
Sbjct: 295 RCIRTNIN 302
>gi|6005723 carbonic anhydrase VB, mitochondrial precursor [Homo
sapiens]
Length = 317
Score = 122 bits (307), Expect = 4e-28
Identities = 80/244 (32%), Positives = 124/244 (50%), Gaps = 12/244 (4%)
Query: 51 GGLLQSPIDLHSDILQYDASLTPLEFQGYNLSANKQFLLTNNGHSVKLNLPSDMH---IQ 107
GG QSPI++ YD L PL Y+ + + NNG+S + I+
Sbjct: 60 GGDRQSPINIRWRDSVYDPGLKPLTIS-YDPATCLH--VWNNGYSFLVEFEDSTDKSVIK 116
Query: 108 G--LQSRYSATQLHLHWGNPNDPHGSEHTVSGQHFAAELHIVHYNSDLYPDASTASNKSE 165
G L+ Y Q H HWG D GSEHTV + F AELH+VH+N+ + + A+ +
Sbjct: 117 GGPLEHNYRLKQFHFHWG-AIDAWGSEHTVDSKCFPAELHLVHWNAVRFENFEDAALEEN 175
Query: 166 GLAVLAVLIEMGSFNPSYDKIFSHLQHVKYKGQEAFVPGFNIEELLPERTAEYYRYRGSL 225
GLAV+ V +++G + K+ L +K+K F+ L+P +Y+ Y GSL
Sbjct: 176 GLAVIGVFLKLGKHHKELQKLVDTLPSIKHKDALVEFGSFDPSCLMP-TCPDYWTYSGSL 234
Query: 226 TTPPCNPTVLWTVFRNPVQISQEQLLALETALYCTHMDDPSPREMINNFRQVQKFDERLV 285
TTPP + +V W + + PV++ +QL T L+ + + + M++NFR +Q R V
Sbjct: 235 TTPPLSESVTWIIKKQPVEVDHDQLEQFRTLLFTS--EGEKEKRMVDNFRPLQPLMNRTV 292
Query: 286 YTSF 289
+SF
Sbjct: 293 RSSF 296
>gi|9951923 carbonic anhydrase XI precursor [Homo sapiens]
Length = 328
Score = 96.7 bits (239), Expect = 3e-20
Identities = 81/271 (29%), Positives = 127/271 (46%), Gaps = 27/271 (9%)
Query: 3 RRSLHAAAVLLLVILKEQPSSPAPVNGSKWTYF---------GPDGENSWSKKYPSCG-G 52
R S A VL + PAP W+Y GP + + C G
Sbjct: 6 RLSAPRALVLWAALGAAAHIGPAPDPEDWWSYKDNLQGNFVPGPPFWGLVNAAWSLCAVG 65
Query: 53 LLQSPIDLHSDILQYDASLTPLEFQ--GYNLSANKQFLLTNNGHSVKLNLPSD---MHIQ 107
QSP+D+ + YD L PL G L L N G V LP+ +++
Sbjct: 66 KRQSPVDVELKRVLYDPFLPPLRLSTGGEKLRGT----LYNTGRHVSF-LPAPRPVVNVS 120
Query: 108 GLQSRYS--ATQLHLHWGNPNDPHGSEHTVSGQHFAAELHIVHYNSDLYPDASTASNKSE 165
G YS ++L L +G D GSEH ++ Q F+AE+ ++H+N +LY + S AS
Sbjct: 121 GGPLLYSHRLSELRLLFG-ARDGAGSEHQINHQGFSAEVQLIHFNQELYGNFSAASRGPN 179
Query: 166 GLAVLAVLIEMGS-FNPSYDKIFSH--LQHVKYKGQEAFVPGFNIEELLPERTAEYYRYR 222
GLA+L++ + + S NP ++ + + + YK F+ ++E L PE + + Y+
Sbjct: 180 GLAILSLFVNVASTSNPFLSRLLNRDTITRISYKNDAYFLQDLSLELLFPE-SFGFITYQ 238
Query: 223 GSLTTPPCNPTVLWTVFRNPVQISQEQLLAL 253
GSL+TPPC+ TV W + + I+ Q+ +L
Sbjct: 239 GSLSTPPCSETVTWILIDRALNITSLQMHSL 269
>gi|239746647 PREDICTED: similar to hCG1646661 [Homo sapiens]
Length = 190
Score = 50.8 bits (120), Expect = 2e-06
Identities = 37/124 (29%), Positives = 55/124 (44%), Gaps = 14/124 (11%)
Query: 142 AELHIVHYNSDLYPDASTASNKSEGL----------AVLAVLIEMGSFNPSYDKIFSHLQ 191
+++H+VH N+ Y A +GL + E N ++ I S L+
Sbjct: 21 SKMHVVHSNTK-YQSMEEAPRHGDGLECRPCCWRTPCTWSPSQEQDCSNTNFCAIVSGLR 79
Query: 192 HVKYKGQEAFVPGFNIEELLPERTAEYYRYRGSLTTPPCNPTVLWTVFRNPVQISQEQLL 251
V + F + + P T+ Y R+ GSLT P C PTVLWTVF +P+ I Q+
Sbjct: 80 KVPEPVN--LMSTFLLASMRPN-TSSYCRFAGSLTPPDCEPTVLWTVFEDPIPIRWVQMT 136
Query: 252 ALET 255
T
Sbjct: 137 LFHT 140
>gi|239757641 PREDICTED: similar to hCG1646661 [Homo sapiens]
Length = 190
Score = 50.1 bits (118), Expect = 3e-06
Identities = 36/122 (29%), Positives = 55/122 (45%), Gaps = 10/122 (8%)
Query: 142 AELHIVHYNSDLYPDASTASNKSEGLAVLAVLIEMG-SFNPSYDKIFSHLQHVKYKGQEA 200
+++H+VH N+ Y A +GL +++PS ++ S+
Sbjct: 21 SKMHVVHSNTK-YQSMEEAPRHGDGLECRPCCWRTPRTWSPSQEQDCSNTNFCAIVSGLR 79
Query: 201 FVPG-------FNIEELLPERTAEYYRYRGSLTTPPCNPTVLWTVFRNPVQISQEQLLAL 253
VP F + + P T+ Y R+ GSLT P C PTVLWTVF +P+ I Q+
Sbjct: 80 KVPEPVNLRSTFLLASMRPN-TSSYCRFAGSLTPPDCEPTVLWTVFEDPIPIRWVQMTLF 138
Query: 254 ET 255
T
Sbjct: 139 HT 140
>gi|239757628 PREDICTED: similar to hCG1646661 [Homo sapiens]
Length = 190
Score = 50.1 bits (118), Expect = 3e-06
Identities = 37/124 (29%), Positives = 55/124 (44%), Gaps = 14/124 (11%)
Query: 142 AELHIVHYNSDLYPDASTASNKSEGLA----------VLAVLIEMGSFNPSYDKIFSHLQ 191
+++H+VH N+ Y A +GL + E N ++ I S L+
Sbjct: 21 SKMHVVHSNTK-YQSMEEAPRHGDGLECRPCCWRTPRTWSPSQEQDCSNTNFCAIVSGLR 79
Query: 192 HVKYKGQEAFVPGFNIEELLPERTAEYYRYRGSLTTPPCNPTVLWTVFRNPVQISQEQLL 251
V + F + + P T+ Y R+ GSLT P C PTVLWTVF +P+ I Q+
Sbjct: 80 KVPEPVN--LMSTFPLASMRPN-TSSYCRFAGSLTPPDCEPTVLWTVFEDPIPIRWVQMT 136
Query: 252 ALET 255
T
Sbjct: 137 LFYT 140
>gi|239752124 PREDICTED: similar to hCG1646661 [Homo sapiens]
Length = 190
Score = 50.1 bits (118), Expect = 3e-06
Identities = 37/124 (29%), Positives = 55/124 (44%), Gaps = 14/124 (11%)
Query: 142 AELHIVHYNSDLYPDASTASNKSEGLA----------VLAVLIEMGSFNPSYDKIFSHLQ 191
+++H+VH N+ Y A +GL + E N ++ I S L+
Sbjct: 21 SKMHVVHSNTK-YQSMEEAPRHGDGLECRPCCWRTPRTWSPSQEQDCSNTNFCAIVSGLR 79
Query: 192 HVKYKGQEAFVPGFNIEELLPERTAEYYRYRGSLTTPPCNPTVLWTVFRNPVQISQEQLL 251
V + F + + P T+ Y R+ GSLT P C PTVLWTVF +P+ I Q+
Sbjct: 80 KVPEPVN--LMSTFPLASMRPN-TSSYCRFAGSLTPPDCEPTVLWTVFEDPIPIRWVQMT 136
Query: 252 ALET 255
T
Sbjct: 137 LFYT 140
>gi|239746634 PREDICTED: similar to hCG1646661 [Homo sapiens]
Length = 190
Score = 50.1 bits (118), Expect = 3e-06
Identities = 37/124 (29%), Positives = 55/124 (44%), Gaps = 14/124 (11%)
Query: 142 AELHIVHYNSDLYPDASTASNKSEGLA----------VLAVLIEMGSFNPSYDKIFSHLQ 191
+++H+VH N+ Y A +GL + E N ++ I S L+
Sbjct: 21 SKMHVVHSNTK-YQSMEEAPRHGDGLECRPCCWRTPRTWSPSQEQDCSNTNFCAIVSGLR 79
Query: 192 HVKYKGQEAFVPGFNIEELLPERTAEYYRYRGSLTTPPCNPTVLWTVFRNPVQISQEQLL 251
V + F + + P T+ Y R+ GSLT P C PTVLWTVF +P+ I Q+
Sbjct: 80 KVPEPVN--LMSTFPLASMRPN-TSSYCRFAGSLTPPDCEPTVLWTVFEDPIPIRWVQMT 136
Query: 252 ALET 255
T
Sbjct: 137 LFYT 140
>gi|7669503 lysosomal-associated membrane protein 2 isoform B
precursor [Homo sapiens]
Length = 410
Score = 30.0 bits (66), Expect = 3.3
Identities = 24/91 (26%), Positives = 44/91 (48%), Gaps = 4/91 (4%)
Query: 245 ISQEQLLALETALYCTHMDDPSPREMINNFRQVQKFDERLVYTSFSQVQVCTAAGLSLG- 303
I+ L + L ++M + ++ Q+ FD R+ + +Q + TA SL
Sbjct: 313 IANNNLSYWDAPLGSSYMCNKEQTVSVSGAFQINTFDLRVQPFNVTQGKYSTAQECSLDD 372
Query: 304 ---IILSLALAGILGICIVVVVSIWLFRRKS 331
+I + AG+ G+ IV+V++ + RRKS
Sbjct: 373 DTILIPIIVGAGLSGLIIVIVIAYVIGRRKS 403
Database: hs.faa
Posted date: Aug 4, 2009 4:42 PM
Number of letters in database: 18,247,518
Number of sequences in database: 37,866
Lambda K H
0.318 0.134 0.405
Gapped
Lambda K H
0.267 0.0410 0.140
Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Hits to DB: 14,438,128
Number of Sequences: 37866
Number of extensions: 662610
Number of successful extensions: 1683
Number of sequences better than 10.0: 30
Number of HSP's better than 10.0 without gapping: 31
Number of HSP's successfully gapped in prelim test: 4
Number of HSP's that attempted gapping in prelim test: 1580
Number of HSP's gapped (non-prelim): 37
length of query: 354
length of database: 18,247,518
effective HSP length: 103
effective length of query: 251
effective length of database: 14,347,320
effective search space: 3601177320
effective search space used: 3601177320
T: 11
A: 40
X1: 16 ( 7.3 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 41 (21.7 bits)
S2: 62 (28.5 bits)
Search results were obtained with NCBI BLAST and RefSeq entries.
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Guide to the Human Genome
Copyright © 2010 by Stewart Scherer. All rights reserved.