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Search of human proteins with 4502169
BLASTP 2.2.11 [Jun-05-2005]
Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer,
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997),
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs", Nucleic Acids Res. 25:3389-3402.
Query= gi|4502169 NEDD8 activating enzyme E1 subunit 1 isoform a [Homo
sapiens]
(534 letters)
Database: hs.faa
37,866 sequences; 18,247,518 total letters
Searching..................................................done
Score E
Sequences producing significant alignments: (bits) Value
gi|4502169 NEDD8 activating enzyme E1 subunit 1 isoform a [Homo ... 1069 0.0
gi|66363686 NEDD8 activating enzyme E1 subunit 1 isoform b [Homo... 1038 0.0
gi|66363688 NEDD8 activating enzyme E1 subunit 1 isoform c [Homo... 894 0.0
gi|7705473 SUMO1 activating enzyme subunit 1 isoform a [Homo sap... 102 9e-22
gi|225543288 SUMO1 activating enzyme subunit 1 isoform c [Homo s... 100 4e-21
gi|225543285 SUMO1 activating enzyme subunit 1 isoform b [Homo s... 100 4e-21
gi|4885585 SUMO1 activating enzyme subunit 1 isoform a [Homo sap... 100 4e-21
gi|23510338 ubiquitin-activating enzyme E1 [Homo sapiens] 79 1e-14
gi|23510340 ubiquitin-activating enzyme E1 [Homo sapiens] 79 1e-14
gi|38045948 ubiquitin-like modifier activating enzyme 7 [Homo sa... 73 6e-13
gi|150417996 ubiquitin-activating enzyme E1-like 2 [Homo sapiens] 64 3e-10
gi|4885649 SUMO-1 activating enzyme subunit 2 [Homo sapiens] 51 3e-06
gi|38045944 ubiquitin-activating enzyme 3 isoform 2 [Homo sapiens] 49 9e-06
gi|38045942 ubiquitin-activating enzyme 3 isoform 1 [Homo sapiens] 49 9e-06
gi|7657339 molybdenum cofactor synthesis 3 [Homo sapiens] 37 0.045
gi|71274148 pleckstrin homology domain containing, family G (wit... 32 1.5
gi|170763513 ATP/GTP binding protein 1 [Homo sapiens] 31 2.5
gi|38327032 ubiquitin-activating enzyme 5 isoform 2 [Homo sapiens] 31 3.2
gi|13376212 ubiquitin-activating enzyme 5 isoform 1 [Homo sapiens] 31 3.2
gi|111548666 SNF2 histone linker PHD RING helicase isoform a [Ho... 31 3.2
gi|27436873 SNF2 histone linker PHD RING helicase isoform b [Hom... 31 3.2
gi|22538387 A-kinase anchor protein 9 isoform 2 [Homo sapiens] 30 5.5
gi|22538393 A-kinase anchor protein 9 isoform 3 [Homo sapiens] 30 5.5
gi|21361724 nuclear transport factor 2-like export factor 2 [Hom... 30 5.5
gi|38373673 synaptonemal complex protein 2 [Homo sapiens] 30 5.5
gi|37594469 3-hydroxyisobutyryl-Coenzyme A hydrolase isoform 2 [... 30 7.2
gi|37594471 3-hydroxyisobutyryl-Coenzyme A hydrolase isoform 1 [... 30 7.2
gi|44890065 hypothetical protein LOC6936 [Homo sapiens] 29 9.4
gi|8923009 non-SMC element 4 homolog A [Homo sapiens] 29 9.4
>gi|4502169 NEDD8 activating enzyme E1 subunit 1 isoform a [Homo
sapiens]
Length = 534
Score = 1069 bits (2765), Expect = 0.0
Identities = 534/534 (100%), Positives = 534/534 (100%)
Query: 1 MAQLGKLLKEQKYDRQLRLWGDHGQEALESAHVCLINATATGTEILKNLVLPGIGSFTII 60
MAQLGKLLKEQKYDRQLRLWGDHGQEALESAHVCLINATATGTEILKNLVLPGIGSFTII
Sbjct: 1 MAQLGKLLKEQKYDRQLRLWGDHGQEALESAHVCLINATATGTEILKNLVLPGIGSFTII 60
Query: 61 DGNQVSGEDAGNNFFLQRSSIGKNRAEAAMEFLQELNSDVSGSFVEESPENLLDNDPSFF 120
DGNQVSGEDAGNNFFLQRSSIGKNRAEAAMEFLQELNSDVSGSFVEESPENLLDNDPSFF
Sbjct: 61 DGNQVSGEDAGNNFFLQRSSIGKNRAEAAMEFLQELNSDVSGSFVEESPENLLDNDPSFF 120
Query: 121 CRFTVVVATQLPESTSLRLADVLWNSQIPLLICRTYGLVGYMRIIIKEHPVIESHPDNAL 180
CRFTVVVATQLPESTSLRLADVLWNSQIPLLICRTYGLVGYMRIIIKEHPVIESHPDNAL
Sbjct: 121 CRFTVVVATQLPESTSLRLADVLWNSQIPLLICRTYGLVGYMRIIIKEHPVIESHPDNAL 180
Query: 181 EDLRLDKPFPELREHFQSYDLDHMEKKDHSHTPWIVIIAKYLAQWYSETNGRIPKTYKEK 240
EDLRLDKPFPELREHFQSYDLDHMEKKDHSHTPWIVIIAKYLAQWYSETNGRIPKTYKEK
Sbjct: 181 EDLRLDKPFPELREHFQSYDLDHMEKKDHSHTPWIVIIAKYLAQWYSETNGRIPKTYKEK 240
Query: 241 EDFRDLIRQGILKNENGAPEDEENFEEAIKNVNTALNTTQIPSSIEDIFNDDRCINITKQ 300
EDFRDLIRQGILKNENGAPEDEENFEEAIKNVNTALNTTQIPSSIEDIFNDDRCINITKQ
Sbjct: 241 EDFRDLIRQGILKNENGAPEDEENFEEAIKNVNTALNTTQIPSSIEDIFNDDRCINITKQ 300
Query: 301 TPSFWILARALKEFVAKEGQGNLPVRGTIPDMIADSGKYIKLQNVYREKAKKDAAAVGNH 360
TPSFWILARALKEFVAKEGQGNLPVRGTIPDMIADSGKYIKLQNVYREKAKKDAAAVGNH
Sbjct: 301 TPSFWILARALKEFVAKEGQGNLPVRGTIPDMIADSGKYIKLQNVYREKAKKDAAAVGNH 360
Query: 361 VAKLLQSIGQAPESISEKELKLLCSNSAFLRVVRCRSLAEEYGLDTINKDEIISSMDNPD 420
VAKLLQSIGQAPESISEKELKLLCSNSAFLRVVRCRSLAEEYGLDTINKDEIISSMDNPD
Sbjct: 361 VAKLLQSIGQAPESISEKELKLLCSNSAFLRVVRCRSLAEEYGLDTINKDEIISSMDNPD 420
Query: 421 NEIVLYLMLRAVDRFHKQQGRYPGVSNYQVEEDIGKLKSCLTGFLQEYGLSVMVKDDYVH 480
NEIVLYLMLRAVDRFHKQQGRYPGVSNYQVEEDIGKLKSCLTGFLQEYGLSVMVKDDYVH
Sbjct: 421 NEIVLYLMLRAVDRFHKQQGRYPGVSNYQVEEDIGKLKSCLTGFLQEYGLSVMVKDDYVH 480
Query: 481 EFCRYGAAEPHTIAAFLGGAAAQEVIKIITKQFVIFNNTYIYSGMSQTSATFQL 534
EFCRYGAAEPHTIAAFLGGAAAQEVIKIITKQFVIFNNTYIYSGMSQTSATFQL
Sbjct: 481 EFCRYGAAEPHTIAAFLGGAAAQEVIKIITKQFVIFNNTYIYSGMSQTSATFQL 534
>gi|66363686 NEDD8 activating enzyme E1 subunit 1 isoform b [Homo
sapiens]
Length = 528
Score = 1038 bits (2685), Expect = 0.0
Identities = 518/525 (98%), Positives = 520/525 (99%)
Query: 10 EQKYDRQLRLWGDHGQEALESAHVCLINATATGTEILKNLVLPGIGSFTIIDGNQVSGED 69
+Q + RLWGDHGQEALESAHVCLINATATGTEILKNLVLPGIGSFTIIDGNQVSGED
Sbjct: 4 QQTKTNEARLWGDHGQEALESAHVCLINATATGTEILKNLVLPGIGSFTIIDGNQVSGED 63
Query: 70 AGNNFFLQRSSIGKNRAEAAMEFLQELNSDVSGSFVEESPENLLDNDPSFFCRFTVVVAT 129
AGNNFFLQRSSIGKNRAEAAMEFLQELNSDVSGSFVEESPENLLDNDPSFFCRFTVVVAT
Sbjct: 64 AGNNFFLQRSSIGKNRAEAAMEFLQELNSDVSGSFVEESPENLLDNDPSFFCRFTVVVAT 123
Query: 130 QLPESTSLRLADVLWNSQIPLLICRTYGLVGYMRIIIKEHPVIESHPDNALEDLRLDKPF 189
QLPESTSLRLADVLWNSQIPLLICRTYGLVGYMRIIIKEHPVIESHPDNALEDLRLDKPF
Sbjct: 124 QLPESTSLRLADVLWNSQIPLLICRTYGLVGYMRIIIKEHPVIESHPDNALEDLRLDKPF 183
Query: 190 PELREHFQSYDLDHMEKKDHSHTPWIVIIAKYLAQWYSETNGRIPKTYKEKEDFRDLIRQ 249
PELREHFQSYDLDHMEKKDHSHTPWIVIIAKYLAQWYSETNGRIPKTYKEKEDFRDLIRQ
Sbjct: 184 PELREHFQSYDLDHMEKKDHSHTPWIVIIAKYLAQWYSETNGRIPKTYKEKEDFRDLIRQ 243
Query: 250 GILKNENGAPEDEENFEEAIKNVNTALNTTQIPSSIEDIFNDDRCINITKQTPSFWILAR 309
GILKNENGAPEDEENFEEAIKNVNTALNTTQIPSSIEDIFNDDRCINITKQTPSFWILAR
Sbjct: 244 GILKNENGAPEDEENFEEAIKNVNTALNTTQIPSSIEDIFNDDRCINITKQTPSFWILAR 303
Query: 310 ALKEFVAKEGQGNLPVRGTIPDMIADSGKYIKLQNVYREKAKKDAAAVGNHVAKLLQSIG 369
ALKEFVAKEGQGNLPVRGTIPDMIADSGKYIKLQNVYREKAKKDAAAVGNHVAKLLQSIG
Sbjct: 304 ALKEFVAKEGQGNLPVRGTIPDMIADSGKYIKLQNVYREKAKKDAAAVGNHVAKLLQSIG 363
Query: 370 QAPESISEKELKLLCSNSAFLRVVRCRSLAEEYGLDTINKDEIISSMDNPDNEIVLYLML 429
QAPESISEKELKLLCSNSAFLRVVRCRSLAEEYGLDTINKDEIISSMDNPDNEIVLYLML
Sbjct: 364 QAPESISEKELKLLCSNSAFLRVVRCRSLAEEYGLDTINKDEIISSMDNPDNEIVLYLML 423
Query: 430 RAVDRFHKQQGRYPGVSNYQVEEDIGKLKSCLTGFLQEYGLSVMVKDDYVHEFCRYGAAE 489
RAVDRFHKQQGRYPGVSNYQVEEDIGKLKSCLTGFLQEYGLSVMVKDDYVHEFCRYGAAE
Sbjct: 424 RAVDRFHKQQGRYPGVSNYQVEEDIGKLKSCLTGFLQEYGLSVMVKDDYVHEFCRYGAAE 483
Query: 490 PHTIAAFLGGAAAQEVIKIITKQFVIFNNTYIYSGMSQTSATFQL 534
PHTIAAFLGGAAAQEVIKIITKQFVIFNNTYIYSGMSQTSATFQL
Sbjct: 484 PHTIAAFLGGAAAQEVIKIITKQFVIFNNTYIYSGMSQTSATFQL 528
>gi|66363688 NEDD8 activating enzyme E1 subunit 1 isoform c [Homo
sapiens]
Length = 445
Score = 894 bits (2311), Expect = 0.0
Identities = 445/445 (100%), Positives = 445/445 (100%)
Query: 90 MEFLQELNSDVSGSFVEESPENLLDNDPSFFCRFTVVVATQLPESTSLRLADVLWNSQIP 149
MEFLQELNSDVSGSFVEESPENLLDNDPSFFCRFTVVVATQLPESTSLRLADVLWNSQIP
Sbjct: 1 MEFLQELNSDVSGSFVEESPENLLDNDPSFFCRFTVVVATQLPESTSLRLADVLWNSQIP 60
Query: 150 LLICRTYGLVGYMRIIIKEHPVIESHPDNALEDLRLDKPFPELREHFQSYDLDHMEKKDH 209
LLICRTYGLVGYMRIIIKEHPVIESHPDNALEDLRLDKPFPELREHFQSYDLDHMEKKDH
Sbjct: 61 LLICRTYGLVGYMRIIIKEHPVIESHPDNALEDLRLDKPFPELREHFQSYDLDHMEKKDH 120
Query: 210 SHTPWIVIIAKYLAQWYSETNGRIPKTYKEKEDFRDLIRQGILKNENGAPEDEENFEEAI 269
SHTPWIVIIAKYLAQWYSETNGRIPKTYKEKEDFRDLIRQGILKNENGAPEDEENFEEAI
Sbjct: 121 SHTPWIVIIAKYLAQWYSETNGRIPKTYKEKEDFRDLIRQGILKNENGAPEDEENFEEAI 180
Query: 270 KNVNTALNTTQIPSSIEDIFNDDRCINITKQTPSFWILARALKEFVAKEGQGNLPVRGTI 329
KNVNTALNTTQIPSSIEDIFNDDRCINITKQTPSFWILARALKEFVAKEGQGNLPVRGTI
Sbjct: 181 KNVNTALNTTQIPSSIEDIFNDDRCINITKQTPSFWILARALKEFVAKEGQGNLPVRGTI 240
Query: 330 PDMIADSGKYIKLQNVYREKAKKDAAAVGNHVAKLLQSIGQAPESISEKELKLLCSNSAF 389
PDMIADSGKYIKLQNVYREKAKKDAAAVGNHVAKLLQSIGQAPESISEKELKLLCSNSAF
Sbjct: 241 PDMIADSGKYIKLQNVYREKAKKDAAAVGNHVAKLLQSIGQAPESISEKELKLLCSNSAF 300
Query: 390 LRVVRCRSLAEEYGLDTINKDEIISSMDNPDNEIVLYLMLRAVDRFHKQQGRYPGVSNYQ 449
LRVVRCRSLAEEYGLDTINKDEIISSMDNPDNEIVLYLMLRAVDRFHKQQGRYPGVSNYQ
Sbjct: 301 LRVVRCRSLAEEYGLDTINKDEIISSMDNPDNEIVLYLMLRAVDRFHKQQGRYPGVSNYQ 360
Query: 450 VEEDIGKLKSCLTGFLQEYGLSVMVKDDYVHEFCRYGAAEPHTIAAFLGGAAAQEVIKII 509
VEEDIGKLKSCLTGFLQEYGLSVMVKDDYVHEFCRYGAAEPHTIAAFLGGAAAQEVIKII
Sbjct: 361 VEEDIGKLKSCLTGFLQEYGLSVMVKDDYVHEFCRYGAAEPHTIAAFLGGAAAQEVIKII 420
Query: 510 TKQFVIFNNTYIYSGMSQTSATFQL 534
TKQFVIFNNTYIYSGMSQTSATFQL
Sbjct: 421 TKQFVIFNNTYIYSGMSQTSATFQL 445
>gi|7705473 SUMO1 activating enzyme subunit 1 isoform a [Homo
sapiens]
Length = 346
Score = 102 bits (254), Expect = 9e-22
Identities = 57/168 (33%), Positives = 86/168 (51%), Gaps = 3/168 (1%)
Query: 12 KYDRQLRLWGDHGQEALESAHVCLINATATGTEILKNLVLPGIGSFTIIDGNQVSGEDAG 71
+YDRQ+RLWG Q+ L ++ V L+ G EI KNL+L G+ T++D QV+ ED G
Sbjct: 18 QYDRQIRLWGLEAQKRLRASRVLLVGLKGLGAEIAKNLILAGVKGLTMLDHEQVTPEDPG 77
Query: 72 NNFFLQRSSIGKNRAEAAMEFLQELNSDVSGSFVEESPENLLDNDPSFFCRFTVVVATQL 131
F ++ S+G+NRAEA++E Q LN V V+ E++ SFF +F V T
Sbjct: 78 AQFLIRTGSVGRNRAEASLERAQNLNPMVD---VKVDTEDIEKKPESFFTQFDAVCLTCC 134
Query: 132 PESTSLRLADVLWNSQIPLLICRTYGLVGYMRIIIKEHPVIESHPDNA 179
+++ + + I +G GY + EH +E D A
Sbjct: 135 SRDVIVKVDQICHKNSIKFFTGDAFGYHGYTFANLGEHEFVEEETDVA 182
Score = 47.4 bits (111), Expect = 3e-05
Identities = 30/100 (30%), Positives = 48/100 (48%), Gaps = 5/100 (5%)
Query: 426 YLMLRAVDRFHKQQGRYPGVSNYQVEEDIGKLKSCLTGFLQEYGLSVMVKDDYVHEFCRY 485
Y +L+ + +F +GR P Y EED L L G+S D +F RY
Sbjct: 240 YFLLQVLLKFRTDKGRDPSSDTY--EEDSELLLQIRNDVLDSLGIS---PDLLPEDFVRY 294
Query: 486 GAAEPHTIAAFLGGAAAQEVIKIITKQFVIFNNTYIYSGM 525
+E + A +GG AQE++K ++++ NN + + GM
Sbjct: 295 CFSEMAPVCAVVGGILAQEIVKALSQRDPPHNNFFFFDGM 334
>gi|225543288 SUMO1 activating enzyme subunit 1 isoform c [Homo
sapiens]
Length = 266
Score = 100 bits (248), Expect = 4e-21
Identities = 55/162 (33%), Positives = 84/162 (51%), Gaps = 3/162 (1%)
Query: 12 KYDRQLRLWGDHGQEALESAHVCLINATATGTEILKNLVLPGIGSFTIIDGNQVSGEDAG 71
+YDRQ+RLWG Q+ L ++ V L+ G EI KNL+L G+ T++D QV+ ED G
Sbjct: 18 QYDRQIRLWGLEAQKRLRASRVLLVGLKGLGAEIAKNLILAGVKGLTMLDHEQVTPEDPG 77
Query: 72 NNFFLQRSSIGKNRAEAAMEFLQELNSDVSGSFVEESPENLLDNDPSFFCRFTVVVATQL 131
F ++ S+G+NRAEA++E Q LN V V+ E++ SFF +F V T
Sbjct: 78 AQFLIRTGSVGRNRAEASLERAQNLNPMVD---VKVDTEDIEKKPESFFTQFDAVCLTCC 134
Query: 132 PESTSLRLADVLWNSQIPLLICRTYGLVGYMRIIIKEHPVIE 173
+++ + + I +G GY + EH +E
Sbjct: 135 SRDVIVKVDQICHKNSIKFFTGDVFGYHGYTFANLGEHEFVE 176
>gi|225543285 SUMO1 activating enzyme subunit 1 isoform b [Homo
sapiens]
Length = 299
Score = 100 bits (248), Expect = 4e-21
Identities = 55/162 (33%), Positives = 84/162 (51%), Gaps = 3/162 (1%)
Query: 12 KYDRQLRLWGDHGQEALESAHVCLINATATGTEILKNLVLPGIGSFTIIDGNQVSGEDAG 71
+YDRQ+RLWG Q+ L ++ V L+ G EI KNL+L G+ T++D QV+ ED G
Sbjct: 18 QYDRQIRLWGLEAQKRLRASRVLLVGLKGLGAEIAKNLILAGVKGLTMLDHEQVTPEDPG 77
Query: 72 NNFFLQRSSIGKNRAEAAMEFLQELNSDVSGSFVEESPENLLDNDPSFFCRFTVVVATQL 131
F ++ S+G+NRAEA++E Q LN V V+ E++ SFF +F V T
Sbjct: 78 AQFLIRTGSVGRNRAEASLERAQNLNPMVD---VKVDTEDIEKKPESFFTQFDAVCLTCC 134
Query: 132 PESTSLRLADVLWNSQIPLLICRTYGLVGYMRIIIKEHPVIE 173
+++ + + I +G GY + EH +E
Sbjct: 135 SRDVIVKVDQICHKNSIKFFTGDVFGYHGYTFANLGEHEFVE 176
>gi|4885585 SUMO1 activating enzyme subunit 1 isoform a [Homo
sapiens]
Length = 346
Score = 100 bits (248), Expect = 4e-21
Identities = 55/162 (33%), Positives = 84/162 (51%), Gaps = 3/162 (1%)
Query: 12 KYDRQLRLWGDHGQEALESAHVCLINATATGTEILKNLVLPGIGSFTIIDGNQVSGEDAG 71
+YDRQ+RLWG Q+ L ++ V L+ G EI KNL+L G+ T++D QV+ ED G
Sbjct: 18 QYDRQIRLWGLEAQKRLRASRVLLVGLKGLGAEIAKNLILAGVKGLTMLDHEQVTPEDPG 77
Query: 72 NNFFLQRSSIGKNRAEAAMEFLQELNSDVSGSFVEESPENLLDNDPSFFCRFTVVVATQL 131
F ++ S+G+NRAEA++E Q LN V V+ E++ SFF +F V T
Sbjct: 78 AQFLIRTGSVGRNRAEASLERAQNLNPMVD---VKVDTEDIEKKPESFFTQFDAVCLTCC 134
Query: 132 PESTSLRLADVLWNSQIPLLICRTYGLVGYMRIIIKEHPVIE 173
+++ + + I +G GY + EH +E
Sbjct: 135 SRDVIVKVDQICHKNSIKFFTGDVFGYHGYTFANLGEHEFVE 176
Score = 48.1 bits (113), Expect = 2e-05
Identities = 44/167 (26%), Positives = 79/167 (47%), Gaps = 15/167 (8%)
Query: 361 VAKLLQSIGQAPESISEKELKLLCSNSAFLR--VVRCRSLAEEYGLDTINKDEIISSMDN 418
VAK+ Q + P++ K KL S + ++ VV C + E +D + ++ +++
Sbjct: 181 VAKVSQGVEDGPDT---KRAKLDSSETTMVKKKVVFC-PVKEALEVDW-SSEKAKAALKR 235
Query: 419 PDNEIVLYLMLRAVDRFHKQQGRYPGVSNYQVEEDIGKLKSCLTGFLQEYGLSVMVKDDY 478
++ Y +L+ + +F +GR P Y EED L L G+S D
Sbjct: 236 TTSD---YFLLQVLLKFRTDKGRDPSSDTY--EEDSELLLQIRNDVLDSLGIS---PDLL 287
Query: 479 VHEFCRYGAAEPHTIAAFLGGAAAQEVIKIITKQFVIFNNTYIYSGM 525
+F RY +E + A +GG AQE++K ++++ NN + + GM
Sbjct: 288 PEDFVRYCFSEMAPVCAVVGGILAQEIVKALSQRDPPHNNFFFFDGM 334
>gi|23510338 ubiquitin-activating enzyme E1 [Homo sapiens]
Length = 1058
Score = 79.0 bits (193), Expect = 1e-14
Identities = 52/160 (32%), Positives = 75/160 (46%), Gaps = 16/160 (10%)
Query: 8 LKEQKYDRQLRLWGDHGQEALESAHVCLINATATGTEILKNLVLPGIGSFTIIDGNQVSG 67
+ E Y RQL + G + L+++ V + G EI KN++L G+ + T+ D
Sbjct: 50 IDEGLYSRQLYVLGHEAMKRLQTSSVLVSGLRGLGVEIAKNIILGGVKAVTLHDQGTAQW 109
Query: 68 EDAGNNFFLQRSSIGKNRAEAAMEFLQELNSDV-----SGSFVEESPENLLDNDPSFFCR 122
D + F+L+ IGKNRAE + L ELNS V +G VE+ F
Sbjct: 110 ADLSSQFYLREEDIGKNRAEVSQPRLAELNSYVPVTAYTGPLVED-----------FLSG 158
Query: 123 FTVVVATQLPESTSLRLADVLWNSQIPLLICRTYGLVGYM 162
F VVV T P LR+ + N I L++ T GL G +
Sbjct: 159 FQVVVLTNTPLEDQLRVGEFCHNRGIKLVVADTRGLFGQL 198
Score = 45.8 bits (107), Expect = 1e-04
Identities = 46/212 (21%), Positives = 87/212 (41%), Gaps = 16/212 (7%)
Query: 7 LLKEQKYDRQLRLWGDHGQEALESAHVCLINATATGTEILKNLVLPGI-----GSFTIID 61
L ++ +YD Q+ ++G QE L L+ A A G E+LKN + G+ G + D
Sbjct: 445 LQRQNRYDGQVAVFGSDLQEKLGKQKYFLVGAGAIGCELLKNFAMIGLGCGEGGEIIVTD 504
Query: 62 GNQVSGEDAGNNFFLQRSSIGKNRAEAAMEFLQELNSDV----SGSFVEESPENLLDNDP 117
+ + + F + + K +++ A ++++N + + V E + D+D
Sbjct: 505 MDTIEKSNLNRQFLFRPWDVTKLKSDTAAAAVRQMNPHIRVTSHQNRVGPDTERIYDDD- 563
Query: 118 SFFCRFTVVVATQLPESTSLRLADVLWNSQIPLLICRTYGLVGYMRIII----KEHPVIE 173
FF V + + + PLL T G G ++++I + + +
Sbjct: 564 -FFQNLDGVANALDNVDARMYMDRRCVYYRKPLLESGTLGTKGNVQVVIPFLTESYSSSQ 622
Query: 174 SHPDNALEDLRLDKPFPELREHFQSYDLDHME 205
P+ ++ L K FP EH + D E
Sbjct: 623 DPPEKSIPICTL-KNFPNAIEHTLQWARDEFE 653
Score = 38.9 bits (89), Expect = 0.012
Identities = 42/220 (19%), Positives = 87/220 (39%), Gaps = 22/220 (10%)
Query: 312 KEFVAKEGQGNLPVRGTIPDMIADSGKYIKLQNVYREKAKKDAAAVGNHVAKLLQSIGQA 371
+E + + G P+ + + D+ + + R + + V +++ G
Sbjct: 204 EEMILTDSNGEQPLSAMVSMVTKDNPGVVTCLDEARHGFESGDFVSFSEVQGMVELNGNQ 263
Query: 372 PESISEKELKLL-------CSNSAFLRVVRCRSLAEEYGLDTINKDEIISSMDNPDNEIV 424
P E+K+L C S F +R +++ I+ +++S+ PD +
Sbjct: 264 P-----MEIKVLGPYTFSICDTSNFSDYIRGGIVSQVKVPKKISFKSLVASLAEPDFVVT 318
Query: 425 ----------LYLMLRAVDRFHKQQGRYPGVSNYQVEEDIGKLKSCLTGFLQEYGLSVMV 474
L++ +A+ +F Q GR P N + ++ L + +
Sbjct: 319 DFAKFSRPAQLHIGFQALHQFCAQHGRPPRPRNEEDAAELVALAQAVNARALPAVQQNNL 378
Query: 475 KDDYVHEFCRYGAAEPHTIAAFLGGAAAQEVIKIITKQFV 514
+D + + A + I AF+GG AAQEV+K + +F+
Sbjct: 379 DEDLIRKLAYVAAGDLAPINAFIGGLAAQEVMKACSGKFM 418
>gi|23510340 ubiquitin-activating enzyme E1 [Homo sapiens]
Length = 1058
Score = 79.0 bits (193), Expect = 1e-14
Identities = 52/160 (32%), Positives = 75/160 (46%), Gaps = 16/160 (10%)
Query: 8 LKEQKYDRQLRLWGDHGQEALESAHVCLINATATGTEILKNLVLPGIGSFTIIDGNQVSG 67
+ E Y RQL + G + L+++ V + G EI KN++L G+ + T+ D
Sbjct: 50 IDEGLYSRQLYVLGHEAMKRLQTSSVLVSGLRGLGVEIAKNIILGGVKAVTLHDQGTAQW 109
Query: 68 EDAGNNFFLQRSSIGKNRAEAAMEFLQELNSDV-----SGSFVEESPENLLDNDPSFFCR 122
D + F+L+ IGKNRAE + L ELNS V +G VE+ F
Sbjct: 110 ADLSSQFYLREEDIGKNRAEVSQPRLAELNSYVPVTAYTGPLVED-----------FLSG 158
Query: 123 FTVVVATQLPESTSLRLADVLWNSQIPLLICRTYGLVGYM 162
F VVV T P LR+ + N I L++ T GL G +
Sbjct: 159 FQVVVLTNTPLEDQLRVGEFCHNRGIKLVVADTRGLFGQL 198
Score = 45.8 bits (107), Expect = 1e-04
Identities = 46/212 (21%), Positives = 87/212 (41%), Gaps = 16/212 (7%)
Query: 7 LLKEQKYDRQLRLWGDHGQEALESAHVCLINATATGTEILKNLVLPGI-----GSFTIID 61
L ++ +YD Q+ ++G QE L L+ A A G E+LKN + G+ G + D
Sbjct: 445 LQRQNRYDGQVAVFGSDLQEKLGKQKYFLVGAGAIGCELLKNFAMIGLGCGEGGEIIVTD 504
Query: 62 GNQVSGEDAGNNFFLQRSSIGKNRAEAAMEFLQELNSDV----SGSFVEESPENLLDNDP 117
+ + + F + + K +++ A ++++N + + V E + D+D
Sbjct: 505 MDTIEKSNLNRQFLFRPWDVTKLKSDTAAAAVRQMNPHIRVTSHQNRVGPDTERIYDDD- 563
Query: 118 SFFCRFTVVVATQLPESTSLRLADVLWNSQIPLLICRTYGLVGYMRIII----KEHPVIE 173
FF V + + + PLL T G G ++++I + + +
Sbjct: 564 -FFQNLDGVANALDNVDARMYMDRRCVYYRKPLLESGTLGTKGNVQVVIPFLTESYSSSQ 622
Query: 174 SHPDNALEDLRLDKPFPELREHFQSYDLDHME 205
P+ ++ L K FP EH + D E
Sbjct: 623 DPPEKSIPICTL-KNFPNAIEHTLQWARDEFE 653
Score = 38.9 bits (89), Expect = 0.012
Identities = 42/220 (19%), Positives = 87/220 (39%), Gaps = 22/220 (10%)
Query: 312 KEFVAKEGQGNLPVRGTIPDMIADSGKYIKLQNVYREKAKKDAAAVGNHVAKLLQSIGQA 371
+E + + G P+ + + D+ + + R + + V +++ G
Sbjct: 204 EEMILTDSNGEQPLSAMVSMVTKDNPGVVTCLDEARHGFESGDFVSFSEVQGMVELNGNQ 263
Query: 372 PESISEKELKLL-------CSNSAFLRVVRCRSLAEEYGLDTINKDEIISSMDNPDNEIV 424
P E+K+L C S F +R +++ I+ +++S+ PD +
Sbjct: 264 P-----MEIKVLGPYTFSICDTSNFSDYIRGGIVSQVKVPKKISFKSLVASLAEPDFVVT 318
Query: 425 ----------LYLMLRAVDRFHKQQGRYPGVSNYQVEEDIGKLKSCLTGFLQEYGLSVMV 474
L++ +A+ +F Q GR P N + ++ L + +
Sbjct: 319 DFAKFSRPAQLHIGFQALHQFCAQHGRPPRPRNEEDAAELVALAQAVNARALPAVQQNNL 378
Query: 475 KDDYVHEFCRYGAAEPHTIAAFLGGAAAQEVIKIITKQFV 514
+D + + A + I AF+GG AAQEV+K + +F+
Sbjct: 379 DEDLIRKLAYVAAGDLAPINAFIGGLAAQEVMKACSGKFM 418
>gi|38045948 ubiquitin-like modifier activating enzyme 7 [Homo
sapiens]
Length = 1012
Score = 73.2 bits (178), Expect = 6e-13
Identities = 52/162 (32%), Positives = 74/162 (45%), Gaps = 16/162 (9%)
Query: 6 KLLKEQKYDRQLRLWGDHGQEALESAHVCLINATATGTEILKNLVLPGIGSFTIIDGNQV 65
KLL E+ Y RQL + G + ++ A V + G E+ KNLVL G+GS T+ D +
Sbjct: 8 KLLDEELYSRQLYVLGSPAMQRIQGARVLVSGLQGLGAEVAKNLVLMGVGSLTLHDPHPT 67
Query: 66 SGEDAGNNFFLQRSSIGKNRAEAAMEFLQELNSDV-----SGSFVEESPENLLDNDPSFF 120
D F L + ++RAEA+ E L +LN V +G E+ LLD
Sbjct: 68 CWSDLAAQFLLSEQDLERSRAEASQELLAQLNRAVQVVVHTGDITEDL---LLD------ 118
Query: 121 CRFTVVVATQLPESTSLRLADVLWNSQIPLLICRTYGLVGYM 162
F VVV T L++ + + L T GLVG +
Sbjct: 119 --FQVVVLTAAKLEEQLKVGTLCHKHGVCFLAADTRGLVGQL 158
Score = 53.9 bits (128), Expect = 4e-07
Identities = 29/98 (29%), Positives = 49/98 (50%), Gaps = 5/98 (5%)
Query: 8 LKEQKYDRQLRLWGDHGQEALESAHVCLINATATGTEILKNLVLPGIGS-----FTIIDG 62
L+ +YD Q+ ++G QE L H L+ A A G E+LK L G+G+ T++D
Sbjct: 410 LRGSRYDGQIAVFGAGFQEKLRRQHYLLVGAGAIGCELLKVFALVGLGAGNSGGLTVVDM 469
Query: 63 NQVSGEDAGNNFFLQRSSIGKNRAEAAMEFLQELNSDV 100
+ + + F + +G+ +AE A + LN D+
Sbjct: 470 DHIERSNLSRQFLFRSQDVGRPKAEVAAAAARGLNPDL 507
>gi|150417996 ubiquitin-activating enzyme E1-like 2 [Homo sapiens]
Length = 1052
Score = 63.9 bits (154), Expect = 3e-10
Identities = 47/139 (33%), Positives = 64/139 (46%), Gaps = 5/139 (3%)
Query: 13 YDRQLRLWGDHGQEALESAHVCLINATATGTEILKNLVLPGIGSFTIIDGNQVSGEDAGN 72
Y RQ + GD + + +HV L G EI KNLVL GI + TI D + D G
Sbjct: 44 YSRQRYVLGDTAMQKMAKSHVFLSGMGGLGLEIAKNLVLAGIKAVTIHDTEKCQAWDLGT 103
Query: 73 NFFLQRSSI--GKNRAEAAMEFLQELNSDVSGSFVEESPENLLDNDPSFFCRFTVVVATQ 130
NFFL + +NRAEA ++ + ELN V S D SF ++ VV T+
Sbjct: 104 NFFLSEDDVVNKRNRAEAVLKHIAELNPYV--HVTSSSVPFNETTDLSFLDKYQCVVLTE 161
Query: 131 LPESTSLRLADVLWNSQIP 149
+ ++ D SQ P
Sbjct: 162 MKLPLQKKIND-FCRSQCP 179
Score = 48.1 bits (113), Expect = 2e-05
Identities = 30/102 (29%), Positives = 52/102 (50%), Gaps = 3/102 (2%)
Query: 412 IISSMDNPDNEIVLYLMLRAVDRFHKQQGRYPGVSNYQVEEDIGKLKSCLTGFLQEYGLS 471
+I NP+ + ++ + A+D+F ++ R P V Q E++ KL + ++ L+E
Sbjct: 312 LIVDFSNPEAPLEIHTAMLALDQFQEKYSRKPNVGCQQDSEELLKLATSISETLEE---K 368
Query: 472 VMVKDDYVHEFCRYGAAEPHTIAAFLGGAAAQEVIKIITKQF 513
V D VH +AA +GG A+QEV+K +T +F
Sbjct: 369 PDVNADIVHWLSWTAQGFLSPLAAAVGGVASQEVLKAVTGKF 410
Score = 48.1 bits (113), Expect = 2e-05
Identities = 52/219 (23%), Positives = 89/219 (40%), Gaps = 14/219 (6%)
Query: 7 LLKEQKYDRQLRLWGDHGQEALESAHVCLINATATGTEILKNLVLPGIGS------FTII 60
L + +YD GD + L++ ++ L+ A G E+LKN L G+G+ T+
Sbjct: 437 LPRGDRYDALRACIGDTLCQKLQNLNIFLVGCGAIGCEMLKNFALLGVGTSKEKGMITVT 496
Query: 61 DGNQVSGEDAGNNFFLQRSSIGKNRAEAAMEFLQELNSD--VSGSFVEESPENLLDNDPS 118
D + + + F + I K ++ A + ++NS + + P +
Sbjct: 497 DPDLIEKSNLNRQFLFRPHHIQKPKSYTAADATLKINSQIKIDAHLNKVCPTTETIYNDE 556
Query: 119 FFCRFTVVVATQLPESTSLRLADVLWNSQI-PLLICRTYGLVGYMRIIIKE-HPVIESHP 176
F+ + V++ T L + R D + + PLL T G G+ +I+ SH
Sbjct: 557 FYTKQDVII-TALDNVEARRYVDSRCLANLRPLLDSGTMGTKGHTEVIVPHLTESYNSHR 615
Query: 177 DNALEDLRLD--KPFPELREHFQSYDLDHMEKKDHSHTP 213
D E++ K FP EH + D E SH P
Sbjct: 616 DPPEEEIPFCTLKSFPAAIEHTIQWARDKFE-SSFSHKP 653
>gi|4885649 SUMO-1 activating enzyme subunit 2 [Homo sapiens]
Length = 640
Score = 50.8 bits (120), Expect = 3e-06
Identities = 35/142 (24%), Positives = 65/142 (45%), Gaps = 1/142 (0%)
Query: 26 EALESAHVCLINATATGTEILKNLVLPGIGSFTIIDGNQVSGEDAGNNFFLQRSSIGKNR 85
EA+ V ++ A G E+LKNLVL G +ID + + + F Q+ +G+++
Sbjct: 13 EAVAGGRVLVVGAGGIGCELLKNLVLTGFSHIDLIDLDTIDVSNLNRQFLFQKKHVGRSK 72
Query: 86 AEAAMEFLQELNSDVSGSFVEESPENLLDNDPSFFCRFTVVVATQLPESTSLRLADVLWN 145
A+ A E + + + +S N D + FF +F +V+ + + +
Sbjct: 73 AQVAKESVLQFYPKANIVAYHDSIMN-PDYNVEFFRQFILVMNALDNRAARNHVNRMCLA 131
Query: 146 SQIPLLICRTYGLVGYMRIIIK 167
+ +PL+ T G +G + I K
Sbjct: 132 ADVPLIESGTAGYLGQVTTIKK 153
>gi|38045944 ubiquitin-activating enzyme 3 isoform 2 [Homo sapiens]
Length = 449
Score = 49.3 bits (116), Expect = 9e-06
Identities = 31/103 (30%), Positives = 49/103 (47%), Gaps = 3/103 (2%)
Query: 25 QEALESAHVCLINATATGTEILKNLVLPGIGSFTIIDGNQVSGEDAGNNFFLQRSSIGKN 84
Q L++ V +I A G E+LKNL L G +ID + + + F + IG+
Sbjct: 50 QFLLDTCKVLVIGAGGLGCELLKNLALSGFRQIHVIDMDTIDVSNLNRQFLFRPKDIGRP 109
Query: 85 RAEAAMEFLQELNSDVSGSFVEESPENLLDNDPSFFCRFTVVV 127
+AE A EF LN V V + D + +F+ +F ++V
Sbjct: 110 KAEVAAEF---LNDRVPNCNVVPHFNKIQDFNDTFYRQFHIIV 149
>gi|38045942 ubiquitin-activating enzyme 3 isoform 1 [Homo sapiens]
Length = 463
Score = 49.3 bits (116), Expect = 9e-06
Identities = 31/103 (30%), Positives = 49/103 (47%), Gaps = 3/103 (2%)
Query: 25 QEALESAHVCLINATATGTEILKNLVLPGIGSFTIIDGNQVSGEDAGNNFFLQRSSIGKN 84
Q L++ V +I A G E+LKNL L G +ID + + + F + IG+
Sbjct: 64 QFLLDTCKVLVIGAGGLGCELLKNLALSGFRQIHVIDMDTIDVSNLNRQFLFRPKDIGRP 123
Query: 85 RAEAAMEFLQELNSDVSGSFVEESPENLLDNDPSFFCRFTVVV 127
+AE A EF LN V V + D + +F+ +F ++V
Sbjct: 124 KAEVAAEF---LNDRVPNCNVVPHFNKIQDFNDTFYRQFHIIV 163
>gi|7657339 molybdenum cofactor synthesis 3 [Homo sapiens]
Length = 460
Score = 37.0 bits (84), Expect = 0.045
Identities = 26/91 (28%), Positives = 42/91 (46%), Gaps = 2/91 (2%)
Query: 12 KYDRQLRL--WGDHGQEALESAHVCLINATATGTEILKNLVLPGIGSFTIIDGNQVSGED 69
+Y RQL L G HGQ L +A V ++ G + + L G+G ++D + V +
Sbjct: 62 RYSRQLVLPELGVHGQLRLGTACVLIVGCGGLGCPLAQYLAAAGVGRLGLVDYDVVEMSN 121
Query: 70 AGNNFFLQRSSIGKNRAEAAMEFLQELNSDV 100
+ G+ +A +A L+ LNS V
Sbjct: 122 LARQVLHGEALAGQAKAFSAAASLRRLNSAV 152
>gi|71274148 pleckstrin homology domain containing, family G (with
RhoGef domain) member 1 [Homo sapiens]
Length = 1385
Score = 32.0 bits (71), Expect = 1.5
Identities = 31/149 (20%), Positives = 64/149 (42%), Gaps = 26/149 (17%)
Query: 247 IRQGILKNENGAPE---DEENFEEAIKNVNTA-LNTTQIPSSIEDIFNDDRCINITKQTP 302
IRQ + + E DE++++ + + +++ LN+T++ C + T P
Sbjct: 538 IRQALFPSRRSPQENEDDEDDYQMFVPSFSSSDLNSTRL------------CEDSTSSRP 585
Query: 303 SFWILARALKEFVAKEGQGNLPVR--------GTIPDMIADSGKYIKLQNVYREKAKKDA 354
W + + E G+ VR T P I S + +LQN + + +++
Sbjct: 586 CSWHMGQM--ESTETSSSGHRIVRRASSAGESNTCPPEIGTSDRTRELQNSPKTEGQEEM 643
Query: 355 AAVGNHVAKLLQSIGQAPESISEKELKLL 383
G+ + + I ++IS ++LKL+
Sbjct: 644 TPFGSSIELTIDDIDHVYDNISYEDLKLM 672
>gi|170763513 ATP/GTP binding protein 1 [Homo sapiens]
Length = 1186
Score = 31.2 bits (69), Expect = 2.5
Identities = 27/116 (23%), Positives = 47/116 (40%), Gaps = 15/116 (12%)
Query: 173 ESHPDNALEDLRL-DKPFPELREHFQSYDLDHMEKKDHSHTPWI--VIIAKYLAQWYSET 229
+ P +EDL++ + FPEL + FQ YDL E K + I+ + S
Sbjct: 369 QQEPGRTIEDLKMYEHLFPELVDDFQDYDLISKEPKPFVFEGKVRGPIVVPTAGEETSGN 428
Query: 230 NGRIPKTY------------KEKEDFRDLIRQGILKNENGAPEDEENFEEAIKNVN 273
+G + K ++K F DL ++ I N+ + + I +V+
Sbjct: 429 SGNLRKVVMKENISSKGDEGEKKSTFMDLAKEDIKDNDRTLQQQPGDQNRTISSVH 484
>gi|38327032 ubiquitin-activating enzyme 5 isoform 2 [Homo sapiens]
Length = 348
Score = 30.8 bits (68), Expect = 3.2
Identities = 19/75 (25%), Positives = 34/75 (45%), Gaps = 1/75 (1%)
Query: 26 EALESAHVCLINATATGTEILKNLVLPGIGSFTIIDGNQVSGEDAGNNFFLQRSSIGKNR 85
E + + V ++ G+ + L GIG + D ++V + N F Q G ++
Sbjct: 13 EKIRTFAVAIVGVGGVGSVTAEMLTRCGIGKLLLFDYDKVELANM-NRLFFQPHQAGLSK 71
Query: 86 AEAAMEFLQELNSDV 100
+AA L+ +N DV
Sbjct: 72 VQAAEHTLRNINPDV 86
>gi|13376212 ubiquitin-activating enzyme 5 isoform 1 [Homo sapiens]
Length = 404
Score = 30.8 bits (68), Expect = 3.2
Identities = 19/75 (25%), Positives = 34/75 (45%), Gaps = 1/75 (1%)
Query: 26 EALESAHVCLINATATGTEILKNLVLPGIGSFTIIDGNQVSGEDAGNNFFLQRSSIGKNR 85
E + + V ++ G+ + L GIG + D ++V + N F Q G ++
Sbjct: 69 EKIRTFAVAIVGVGGVGSVTAEMLTRCGIGKLLLFDYDKVELANM-NRLFFQPHQAGLSK 127
Query: 86 AEAAMEFLQELNSDV 100
+AA L+ +N DV
Sbjct: 128 VQAAEHTLRNINPDV 142
>gi|111548666 SNF2 histone linker PHD RING helicase isoform a [Homo
sapiens]
Length = 1687
Score = 30.8 bits (68), Expect = 3.2
Identities = 20/78 (25%), Positives = 33/78 (42%), Gaps = 21/78 (26%)
Query: 154 RTYGLVGYMRIIIKEHPVIESHPDNALEDLRLDKPFPELREHFQS--------------- 198
R + M ++I HP I L D RL++ +LREH+ S
Sbjct: 1077 RLHATHNLMELLIARHPGIPP----TLRDGRLEEEAKQLREHYMSKCNTEVAEAQQALYP 1132
Query: 199 --YDLDHMEKKDHSHTPW 214
+ +++K HS++PW
Sbjct: 1133 VQQTIHELQRKIHSNSPW 1150
>gi|27436873 SNF2 histone linker PHD RING helicase isoform b [Homo
sapiens]
Length = 1659
Score = 30.8 bits (68), Expect = 3.2
Identities = 20/78 (25%), Positives = 33/78 (42%), Gaps = 21/78 (26%)
Query: 154 RTYGLVGYMRIIIKEHPVIESHPDNALEDLRLDKPFPELREHFQS--------------- 198
R + M ++I HP I L D RL++ +LREH+ S
Sbjct: 1077 RLHATHNLMELLIARHPGIPP----TLRDGRLEEEAKQLREHYMSKCNTEVAEAQQALYP 1132
Query: 199 --YDLDHMEKKDHSHTPW 214
+ +++K HS++PW
Sbjct: 1133 VQQTIHELQRKIHSNSPW 1150
>gi|22538387 A-kinase anchor protein 9 isoform 2 [Homo sapiens]
Length = 3907
Score = 30.0 bits (66), Expect = 5.5
Identities = 13/42 (30%), Positives = 23/42 (54%)
Query: 235 KTYKEKEDFRDLIRQGILKNENGAPEDEENFEEAIKNVNTAL 276
+ Y+E + +L+RQ ++ ED+E +E IK +N L
Sbjct: 1596 RQYQEHQQATELLRQAHMRQMERQREDQEQLQEEIKRLNRQL 1637
>gi|22538393 A-kinase anchor protein 9 isoform 3 [Homo sapiens]
Length = 3899
Score = 30.0 bits (66), Expect = 5.5
Identities = 13/42 (30%), Positives = 23/42 (54%)
Query: 235 KTYKEKEDFRDLIRQGILKNENGAPEDEENFEEAIKNVNTAL 276
+ Y+E + +L+RQ ++ ED+E +E IK +N L
Sbjct: 1596 RQYQEHQQATELLRQAHMRQMERQREDQEQLQEEIKRLNRQL 1637
>gi|21361724 nuclear transport factor 2-like export factor 2 [Homo
sapiens]
Length = 197
Score = 30.0 bits (66), Expect = 5.5
Identities = 25/84 (29%), Positives = 34/84 (40%), Gaps = 2/84 (2%)
Query: 59 IIDGNQVSGEDAGNNFF--LQRSSIGKNRAEAAMEFLQELNSDVSGSFVEESPENLLDND 116
I +GN VSG DA NNFF L S N + Q S + V N
Sbjct: 102 IWNGNAVSGLDALNNFFDTLPSSEFQVNMLDCQPVHEQATQSQTTVLVVTSGTVKFDGNK 161
Query: 117 PSFFCRFTVVVATQLPESTSLRLA 140
FF + ++ A P +T ++A
Sbjct: 162 QHFFNQNFLLTAQSTPNNTVWKIA 185
>gi|38373673 synaptonemal complex protein 2 [Homo sapiens]
Length = 1530
Score = 30.0 bits (66), Expect = 5.5
Identities = 21/99 (21%), Positives = 44/99 (44%), Gaps = 5/99 (5%)
Query: 218 IAKYLAQWYSETNGRIP-KTYKEKEDFRDLIRQGILKNENGAPEDEENFEEAIKNVNTAL 276
I K + + E R+P K K K++++DL + + +EN +N+++ +
Sbjct: 999 ITKKMDKTIPEGRIRLPRKATKTKKNYKDLSNSESECEQEFSHSFKENIPVKEENIHSRM 1058
Query: 277 NTTQIPSSIEDIFNDDRCINITKQTPSFWILARALKEFV 315
T ++P + +F C K+ W + LK+ +
Sbjct: 1059 KTVKLPKKQQKVF----CAETEKELSKQWKNSSLLKDAI 1093
>gi|37594469 3-hydroxyisobutyryl-Coenzyme A hydrolase isoform 2
[Homo sapiens]
Length = 338
Score = 29.6 bits (65), Expect = 7.2
Identities = 19/68 (27%), Positives = 32/68 (47%)
Query: 79 SSIGKNRAEAAMEFLQELNSDVSGSFVEESPENLLDNDPSFFCRFTVVVATQLPESTSLR 138
S I ++++ E + ++NS S + VEE ENL + SF V+ P S +
Sbjct: 251 SKIDRDKSFILEEHMDKINSCFSANTVEEIIENLQQDGSSFALEQLKVINKMSPTSLKIT 310
Query: 139 LADVLWNS 146
L ++ S
Sbjct: 311 LRQLMEGS 318
>gi|37594471 3-hydroxyisobutyryl-Coenzyme A hydrolase isoform 1
[Homo sapiens]
Length = 386
Score = 29.6 bits (65), Expect = 7.2
Identities = 19/68 (27%), Positives = 32/68 (47%)
Query: 79 SSIGKNRAEAAMEFLQELNSDVSGSFVEESPENLLDNDPSFFCRFTVVVATQLPESTSLR 138
S I ++++ E + ++NS S + VEE ENL + SF V+ P S +
Sbjct: 251 SKIDRDKSFILEEHMDKINSCFSANTVEEIIENLQQDGSSFALEQLKVINKMSPTSLKIT 310
Query: 139 LADVLWNS 146
L ++ S
Sbjct: 311 LRQLMEGS 318
>gi|44890065 hypothetical protein LOC6936 [Homo sapiens]
Length = 781
Score = 29.3 bits (64), Expect = 9.4
Identities = 16/59 (27%), Positives = 30/59 (50%), Gaps = 5/59 (8%)
Query: 125 VVVATQLPESTSLRLADVLWNSQIPLLICRTYGLVGYMRIIIKEHPVIESHPDNALEDL 183
++ T +P T + LW+ PL +T L+ + R+I++EH E+ + +DL
Sbjct: 553 IINKTIIPRLTDF--VEFLWD---PLSTSQTTSLITHCRVILEEHSTCENEVSKSRQDL 606
>gi|8923009 non-SMC element 4 homolog A [Homo sapiens]
Length = 385
Score = 29.3 bits (64), Expect = 9.4
Identities = 19/82 (23%), Positives = 37/82 (45%), Gaps = 6/82 (7%)
Query: 345 VYREKAKKDAAAVGNHVAKLLQSIGQAPESISEKELKLLCSNSAFLRVVRCRSLAEEYGL 404
++ E ++ A + H L +G EK +L S+F + +L G+
Sbjct: 120 LFNEVSRAREAVLDAHFLVLASDLG------IEKAKQLRSDLSSFDMLRYVETLLTHMGV 173
Query: 405 DTINKDEIISSMDNPDNEIVLY 426
+ + +E+I D+PD E ++Y
Sbjct: 174 NPLEAEELIRDEDSPDFEFIVY 195
Database: hs.faa
Posted date: Aug 4, 2009 4:42 PM
Number of letters in database: 18,247,518
Number of sequences in database: 37,866
Lambda K H
0.318 0.135 0.391
Gapped
Lambda K H
0.267 0.0410 0.140
Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Hits to DB: 19,640,301
Number of Sequences: 37866
Number of extensions: 877892
Number of successful extensions: 1969
Number of sequences better than 10.0: 29
Number of HSP's better than 10.0 without gapping: 19
Number of HSP's successfully gapped in prelim test: 10
Number of HSP's that attempted gapping in prelim test: 1926
Number of HSP's gapped (non-prelim): 44
length of query: 534
length of database: 18,247,518
effective HSP length: 107
effective length of query: 427
effective length of database: 14,195,856
effective search space: 6061630512
effective search space used: 6061630512
T: 11
A: 40
X1: 16 ( 7.3 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 41 (21.7 bits)
S2: 64 (29.3 bits)
Search results were obtained with NCBI BLAST and RefSeq entries.
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Guide to the Human Genome
Copyright © 2010 by Stewart Scherer. All rights reserved.