Guide to the Human Genome
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Name: NAE1 Sequence: fasta or formatted (534aa) NCBI GI: 4502169
Description:

NEDD8 activating enzyme E1 subunit 1 isoform a

Referenced in:

Additional Brain Proteins
Ubiquitin and Related Protein Modifications

Other entries for this name:
alt prot [528aa] NEDD8 activating enzyme E1 subunit 1 isoform b
alt prot [445aa] NEDD8 activating enzyme E1 subunit 1 isoform c
Composition:

amino acid map
 Amino acid        Percentage    Count  Longest homopolymer
 A alanine             7.1         38           3
 C cysteine            1.5          8           1
 D aspartate           5.8         31           2
 E glutamate           8.2         44           2
 F phenylalanine       4.3         23           2
 G glycine             6.0         32           2
 H histidine           2.2         12           1
 I isoleucine          7.7         41           3
 K lysine              6.2         33           2
 L leucine             9.7         52           2
 M methionine          1.7          9           1
 N asparagine          5.6         30           2
 P proline             3.7         20           1
 Q glutamine           4.9         26           2
 R arginine            4.5         24           1
 S serine              6.6         35           2
 T threonine           4.5         24           2
 V valine              5.4         29           3
 W tryptophan          0.9          5           1
 Y tyrosine            3.4         18           1
Comparative genomics:

Search single species RefSeq proteins at NCBI
   H. sapiens
   M. musculus
   D. rerio
   C. intestinalis
   S. purpuratus
   D. melanogaster
   C. elegans
   A. thaliana
   S. cerevisiae
   E. coli W3110
   A. pernix K1

Search summary

comparative genomics plot

   Figure data

Additional searches of
RefSeq proteins at NCBI

   All
   Eukaryotes
   Bacteria
   Archaea
   Viruses
   Primates
   Mammals
   Vertebrates

Related human proteins:
Protein          Relative score         Description

Self-match            1.000   NEDD8 activating enzyme E1 subunit 1 isoform a 
NAE1                  0.970   NEDD8 activating enzyme E1 subunit 1 isoform b [Homo...
NAE1                  0.832   NEDD8 activating enzyme E1 subunit 1 isoform c [Homo...
SAE1                  0.074   SUMO1 activating enzyme subunit 1 isoform a 
SAE1                  0.072   SUMO1 activating enzyme subunit 1 isoform c 
SAE1                  0.072   SUMO1 activating enzyme subunit 1 isoform b 
SAE1                  0.072   SUMO1 activating enzyme subunit 1 isoform a 
UBA1                  0.052   ubiquitin-activating enzyme E1 
UBA1                  0.052   ubiquitin-activating enzyme E1 
UBA7                  0.046   ubiquitin-like modifier activating enzyme 7 
UBA6                  0.037   ubiquitin-activating enzyme E1-like 2 
UBA2                  0.025   SUMO-1 activating enzyme subunit 2 
UBA3                  0.023   ubiquitin-activating enzyme 3 isoform 2 
UBA3                  0.023   ubiquitin-activating enzyme 3 isoform 1 
MOCS3                 0.011   molybdenum cofactor synthesis 3 
PLEKHG1               0.007   pleckstrin homology domain containing, family G (wit...
AGTPBP1               0.006   ATP/GTP binding protein 1 
UBA5                  0.006   ubiquitin-activating enzyme 5 isoform 2 
UBA5                  0.006   ubiquitin-activating enzyme 5 isoform 1 
SHPRH                 0.006   SNF2 histone linker PHD RING helicase isoform a [Ho...
SHPRH                 0.006   SNF2 histone linker PHD RING helicase isoform b [Hom...
AKAP9                 0.005   A-kinase anchor protein 9 isoform 2 
AKAP9                 0.005   A-kinase anchor protein 9 isoform 3 
NXT2                  0.005   nuclear transport factor 2-like export factor 2 [Hom...
SYCP2                 0.005   synaptonemal complex protein 2 
HIBCH                 0.005   3-hydroxyisobutyryl-Coenzyme A hydrolase isoform 2 [...
HIBCH                 0.005   3-hydroxyisobutyryl-Coenzyme A hydrolase isoform 1 [...
C2orf3                0.004   hypothetical protein LOC6936 
NSMCE4A               0.004   non-SMC element 4 homolog A 
Human BLASTP results (used to prepare the table)

Gene descriptions are from NCBI RefSeq. Search results were obtained with NCBI BLAST and RefSeq entries. When identical proteins are present, the self-match may not be listed first in BLASTP output. In such cases, the table above has been reordered to place it first.

See About the Figures for the scoring system used in the figure above right. The same scoring system was used in the table of BLASTP results.


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Guide to the Human Genome
Copyright © 2010 by Stewart Scherer. All rights reserved.

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