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Search of human proteins with 4502057
BLASTP 2.2.11 [Jun-05-2005]
Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer,
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997),
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs", Nucleic Acids Res. 25:3389-3402.
Query= gi|4502057 arachidonate 5-lipoxygenase [Homo sapiens]
(674 letters)
Database: hs.faa
37,866 sequences; 18,247,518 total letters
Searching..................................................done
Score E
Sequences producing significant alignments: (bits) Value
gi|4502057 arachidonate 5-lipoxygenase [Homo sapiens] 1391 0.0
gi|85067501 arachidonate 15-lipoxygenase, second type isoform d ... 557 e-158
gi|4502053 arachidonate 12-lipoxygenase, 12R type [Homo sapiens] 536 e-152
gi|154426292 arachidonate 12-lipoxygenase [Homo sapiens] 522 e-148
gi|182765464 arachidonate lipoxygenase 3 [Homo sapiens] 518 e-147
gi|85067499 arachidonate 15-lipoxygenase, second type isoform a ... 516 e-146
gi|40316937 arachidonate 15-lipoxygenase [Homo sapiens] 499 e-141
gi|85067503 arachidonate 15-lipoxygenase, second type isoform b ... 460 e-129
gi|5174633 receptor for egg jelly-like protein precursor [Homo s... 65 2e-10
gi|239050813 lipoxygenase homology domains 1 isoform 1 [Homo sap... 59 1e-08
gi|224458290 lipoxygenase homology domains 1 isoform 3 [Homo sap... 51 3e-06
gi|239754889 PREDICTED: similar to hCG2036697 [Homo sapiens] 48 3e-05
gi|239749428 PREDICTED: hypothetical protein XP_002347033 [Homo ... 48 3e-05
gi|239743562 PREDICTED: hypothetical protein XP_002342894 [Homo ... 48 3e-05
gi|224458288 lipoxygenase homology domains 1 isoform 2 [Homo sap... 47 4e-05
gi|239756622 PREDICTED: polycystic kidney disease 1-like 3 [Homo... 46 1e-04
gi|239751108 PREDICTED: polycystic kidney disease 1-like 3 [Homo... 46 1e-04
gi|239745596 PREDICTED: polycystin 1-like 3 [Homo sapiens] 46 1e-04
gi|31559825 polycystin 1-like 3 [Homo sapiens] 46 1e-04
gi|116006951 polycystin 1-like 2 isoform a [Homo sapiens] 45 3e-04
gi|19923084 polycystin-1L1 [Homo sapiens] 41 0.004
gi|56790932 echinoderm microtubule associated protein like 1 iso... 33 0.86
gi|56790930 echinoderm microtubule associated protein like 1 iso... 33 0.86
gi|205360962 polycystin 1 isoform 2 precursor [Homo sapiens] 33 1.1
gi|205360954 polycystin 1 isoform 1 precursor [Homo sapiens] 33 1.1
gi|38348294 hypothetical protein LOC339145 [Homo sapiens] 32 2.5
gi|22749183 leucine rich repeat and Ig domain containing 2 [Homo... 31 3.3
gi|239049540 FCH domain only 1 isoform c [Homo sapiens] 31 4.3
gi|239049457 FCH domain only 1 isoform b [Homo sapiens] 31 4.3
gi|29789054 FCH domain only 1 isoform b [Homo sapiens] 31 4.3
>gi|4502057 arachidonate 5-lipoxygenase [Homo sapiens]
Length = 674
Score = 1391 bits (3601), Expect = 0.0
Identities = 674/674 (100%), Positives = 674/674 (100%)
Query: 1 MPSYTVTVATGSQWFAGTDDYIYLSLVGSAGCSEKHLLDKPFYNDFERGAVDSYDVTVDE 60
MPSYTVTVATGSQWFAGTDDYIYLSLVGSAGCSEKHLLDKPFYNDFERGAVDSYDVTVDE
Sbjct: 1 MPSYTVTVATGSQWFAGTDDYIYLSLVGSAGCSEKHLLDKPFYNDFERGAVDSYDVTVDE 60
Query: 61 ELGEIQLVRIEKRKYWLNDDWYLKYITLKTPHGDYIEFPCYRWITGDVEVVLRDGRAKLA 120
ELGEIQLVRIEKRKYWLNDDWYLKYITLKTPHGDYIEFPCYRWITGDVEVVLRDGRAKLA
Sbjct: 61 ELGEIQLVRIEKRKYWLNDDWYLKYITLKTPHGDYIEFPCYRWITGDVEVVLRDGRAKLA 120
Query: 121 RDDQIHILKQHRRKELETRQKQYRWMEWNPGFPLSIDAKCHKDLPRDIQFDSEKGVDFVL 180
RDDQIHILKQHRRKELETRQKQYRWMEWNPGFPLSIDAKCHKDLPRDIQFDSEKGVDFVL
Sbjct: 121 RDDQIHILKQHRRKELETRQKQYRWMEWNPGFPLSIDAKCHKDLPRDIQFDSEKGVDFVL 180
Query: 181 NYSKAMENLFINRFMHMFQSSWNDFADFEKIFVKISNTISERVMNHWQEDLMFGYQFLNG 240
NYSKAMENLFINRFMHMFQSSWNDFADFEKIFVKISNTISERVMNHWQEDLMFGYQFLNG
Sbjct: 181 NYSKAMENLFINRFMHMFQSSWNDFADFEKIFVKISNTISERVMNHWQEDLMFGYQFLNG 240
Query: 241 CNPVLIRRCTELPEKLPVTTEMVECSLERQLSLEQEVQQGNIFIVDFELLDGIDANKTDP 300
CNPVLIRRCTELPEKLPVTTEMVECSLERQLSLEQEVQQGNIFIVDFELLDGIDANKTDP
Sbjct: 241 CNPVLIRRCTELPEKLPVTTEMVECSLERQLSLEQEVQQGNIFIVDFELLDGIDANKTDP 300
Query: 301 CTLQFLAAPICLLYKNLANKIVPIAIQLNQIPGDENPIFLPSDAKYDWLLAKIWVRSSDF 360
CTLQFLAAPICLLYKNLANKIVPIAIQLNQIPGDENPIFLPSDAKYDWLLAKIWVRSSDF
Sbjct: 301 CTLQFLAAPICLLYKNLANKIVPIAIQLNQIPGDENPIFLPSDAKYDWLLAKIWVRSSDF 360
Query: 361 HVHQTITHLLRTHLVSEVFGIAMYRQLPAVHPIFKLLVAHVRFTIAINTKAREQLICECG 420
HVHQTITHLLRTHLVSEVFGIAMYRQLPAVHPIFKLLVAHVRFTIAINTKAREQLICECG
Sbjct: 361 HVHQTITHLLRTHLVSEVFGIAMYRQLPAVHPIFKLLVAHVRFTIAINTKAREQLICECG 420
Query: 421 LFDKANATGGGGHVQMVQRAMKDLTYASLCFPEAIKARGMESKEDIPYYFYRDDGLLVWE 480
LFDKANATGGGGHVQMVQRAMKDLTYASLCFPEAIKARGMESKEDIPYYFYRDDGLLVWE
Sbjct: 421 LFDKANATGGGGHVQMVQRAMKDLTYASLCFPEAIKARGMESKEDIPYYFYRDDGLLVWE 480
Query: 481 AIRTFTAEVVDIYYEGDQVVEEDPELQDFVNDVYVYGMRGRKSSGFPKSVKSREQLSEYL 540
AIRTFTAEVVDIYYEGDQVVEEDPELQDFVNDVYVYGMRGRKSSGFPKSVKSREQLSEYL
Sbjct: 481 AIRTFTAEVVDIYYEGDQVVEEDPELQDFVNDVYVYGMRGRKSSGFPKSVKSREQLSEYL 540
Query: 541 TVVIFTASAQHAAVNFGQYDWCSWIPNAPPTMRAPPPTAKGVVTIEQIVDTLPDRGRSCW 600
TVVIFTASAQHAAVNFGQYDWCSWIPNAPPTMRAPPPTAKGVVTIEQIVDTLPDRGRSCW
Sbjct: 541 TVVIFTASAQHAAVNFGQYDWCSWIPNAPPTMRAPPPTAKGVVTIEQIVDTLPDRGRSCW 600
Query: 601 HLGAVWALSQFQENELFLGMYPEEHFIEKPVKEAMARFRKNLEAIVSVIAERNKKKQLPY 660
HLGAVWALSQFQENELFLGMYPEEHFIEKPVKEAMARFRKNLEAIVSVIAERNKKKQLPY
Sbjct: 601 HLGAVWALSQFQENELFLGMYPEEHFIEKPVKEAMARFRKNLEAIVSVIAERNKKKQLPY 660
Query: 661 YYLSPDRIPNSVAI 674
YYLSPDRIPNSVAI
Sbjct: 661 YYLSPDRIPNSVAI 674
>gi|85067501 arachidonate 15-lipoxygenase, second type isoform d
[Homo sapiens]
Length = 676
Score = 557 bits (1435), Expect = e-158
Identities = 288/682 (42%), Positives = 426/682 (62%), Gaps = 14/682 (2%)
Query: 1 MPSYTVTVATGSQWFAGTDDYIYLSLVGSAGCSEKHLLDKPFYNDFERGAVDSYDVTVDE 60
M + V V+TG + AGT D + +S+VG+ G S LD +F GA + + VT+ E
Sbjct: 1 MAEFRVRVSTGEAFGAGTWDKVSVSIVGTRGESPPLPLDN-LGKEFTAGAEEDFQVTLPE 59
Query: 61 ELGEIQLVRIEKRKYWLN-------DDWYLKYITLKTPHGDYIEFPCYRWITGDVEVVLR 113
++G + L+R+ K L D W+ ++ L P G ++ FPCY+W+ G +VL+
Sbjct: 60 DVGRVLLLRVHKAPPVLPLLGPLAPDAWFCRWFQLTPPRGGHLLFPCYQWLEGAGTLVLQ 119
Query: 114 DGRAKLARDDQIHILKQHRRKELETRQKQYRWMEWNPGFPLSIDAKCHKDLPRDIQFDSE 173
+G AK++ D +L+Q R++EL+ RQ+ Y+W +NPG+P +D K +DL +I++ +
Sbjct: 120 EGTAKVSWADHHPVLQQQRQEELQARQEMYQWKAYNPGWPHCLDEKTVEDLELNIKYSTA 179
Query: 174 KGVDFVLNYSKAMENLFINRFMHMFQSSWNDFADFEKIFVKISNTISERVMNHWQEDLMF 233
K +F L A + I + + W + ++IF +E HWQED F
Sbjct: 180 KNANFYLQAGSAFAEMKIKGLLDR-KGLWRSLNEMKRIFNFRRTPAAEHAFEHWQEDAFF 238
Query: 234 GYQFLNGCNPVLIRRCTELPEKLPVTTEMVECSLERQLSLEQEVQQGNIFIVDFELLDGI 293
QFLNG NPVLIRRC LP+ PVT MV L SL+ E+++G++F+VD +L GI
Sbjct: 239 ASQFLNGLNPVLIRRCHYLPKNFPVTDAMVASVLGPGTSLQAELEKGSLFLVDHGILSGI 298
Query: 294 DANKTDPCTLQFLAAPICLLYKNLA-NKIVPIAIQLNQIPGDENPIFLPSDAKYDWLLAK 352
N + QF AAP+ LLY++ ++P+AIQL+Q PG +PIFLP+D K+DWLLAK
Sbjct: 299 QTNVINGKP-QFSAAPMTLLYQSPGCGPLLPLAIQLSQTPGPNSPIFLPTDDKWDWLLAK 357
Query: 353 IWVRSSDFHVHQTITHLLRTHLVSEVFGIAMYRQLPAVHPIFKLLVAHVRFTIAINTKAR 412
WVR+++F H+ +THLL +HL+ EVF +A RQLP HP+FKLL+ H R+T+ INT AR
Sbjct: 358 TWVRNAEFSFHEALTHLLHSHLLPEVFTLATLRQLPHCHPLFKLLIPHTRYTLHINTLAR 417
Query: 413 EQLICECGLFDKANATGGGGHVQMVQRAMKDLTYASLCFPEAIKARGMESKEDIPYYFYR 472
E LI + D++ G G +++QR MK L Y+ LC PE I+ RG+E DIP Y+YR
Sbjct: 418 ELLIVPGQVVDRSTGIGIEGFSELIQRNMKQLNYSLLCLPEDIRTRGVE---DIPGYYYR 474
Query: 473 DDGLLVWEAIRTFTAEVVDIYYEGDQVVEEDPELQDFVNDVYVYGMRGRKSSGFPKSVKS 532
DDG+ +W A+ F +E++ IYY D+ V++D ELQ +V +++ G ++SSG P S+++
Sbjct: 475 DDGMQIWGAVERFVSEIIGIYYPSDESVQDDRELQAWVREIFSKGFLNQESSGIPSSLET 534
Query: 533 REQLSEYLTVVIFTASAQHAAVNFGQYDWCSWIPNAPPTMRAPPPTAKGVVTIEQIVDTL 592
RE L +Y+T+VIFT SA+HAAV+ GQ+D C+W+PN PP+M+ PPPT+KG+ T E + TL
Sbjct: 535 REALVQYVTMVIFTCSAKHAAVSAGQFDSCAWMPNLPPSMQLPPPTSKGLATCEGFIATL 594
Query: 593 PDRGRSCWHLGAVWALSQFQENELFLGMYPEEHFIEKPVKEAMARFRKNLEAIVSVIAER 652
P +C + A+W LS+ ++ LG YP+EHF E+ + ++A F+ L I I ER
Sbjct: 595 PPVNATCDVILALWLLSKEPGDQRPLGTYPDEHFTEEAPRRSIATFQSRLAQISRGIQER 654
Query: 653 NKKKQLPYYYLSPDRIPNSVAI 674
N+ LPY YL P I NSV+I
Sbjct: 655 NQGLVLPYTYLDPPLIENSVSI 676
>gi|4502053 arachidonate 12-lipoxygenase, 12R type [Homo sapiens]
Length = 701
Score = 536 bits (1381), Expect = e-152
Identities = 282/707 (39%), Positives = 414/707 (58%), Gaps = 39/707 (5%)
Query: 1 MPSYTVTVATGSQWFAGTDDYIYLSLVGSAGCSEKHLLDKPFYNDFERGAVDSYDVTVDE 60
M +Y V VATG+ +GT D I L++VG+ G S K LL+ F DF GAV Y V +
Sbjct: 1 MATYKVRVATGTDLLSGTRDSISLTIVGTQGESHKQLLNH-FGRDFATGAVGQYTVQCPQ 59
Query: 61 ELGEIQLVRIEKRKY--WLNDDWYLKYITLKTPHGDYIEFPCYRWITGDVEVVLRDGRAK 118
+LGE+ ++R+ K +Y + D WY Y+ + P+G FP Y+W+ G + LR+ K
Sbjct: 60 DLGELIIIRLHKERYAFFPKDPWYCNYVQICAPNGRIYHFPAYQWMDGYETLALREATGK 119
Query: 119 LARDDQIHILKQHRRKELETRQKQYRWM----------------------------EWN- 149
DD + +L +HR++E+ +Q Y W EWN
Sbjct: 120 TTADDSLPVLLEHRKEEIRAKQDFYHWRVFLPGLPSYVHIPSYRPPVRRHRNPNRPEWNG 179
Query: 150 --PGFPLSIDAKCHKDLPRDIQFDSEKGVDFVLNYSKAMENLFINRFMHMFQSSWNDFAD 207
PGFP+ I+ K K L ++++ K F + M F R + + SW D
Sbjct: 180 YIPGFPILINFKATKFLNLNLRYSFLKTASFFVRLG-PMALAFKVRGLLDCKHSWKRLKD 238
Query: 208 FEKIFVKISNTISERVMNHWQEDLMFGYQFLNGCNPVLIRRCTELPEKLPVTTEMVECSL 267
KIF + +SE V HW ED FGYQ+LNG NP LIRRCT +P+K PVT +MV L
Sbjct: 239 IRKIFPGKKSVVSEYVAEHWAEDTFFGYQYLNGVNPGLIRRCTRIPDKFPVTDDMVAPFL 298
Query: 268 ERQLSLEQEVQQGNIFIVDFELLDGIDANKTDPCTLQFLAAPICLLYKNLANKIVPIAIQ 327
L+ E+++GNI++ D+ +++GI + Q AP+CLL+ K++PIAIQ
Sbjct: 299 GEGTCLQAELEKGNIYLADYRIMEGIPTVELSG-RKQHHCAPLCLLHFGPEGKMMPIAIQ 357
Query: 328 LNQIPGDENPIFLPSDAKYDWLLAKIWVRSSDFHVHQTITHLLRTHLVSEVFGIAMYRQL 387
L+Q PG + PIFLPSD+++DWLLAK WVR ++F+ H+ I HLL THL++E F +A+ R L
Sbjct: 358 LSQTPGPDCPIFLPSDSEWDWLLAKTWVRYAEFYSHEAIAHLLETHLIAEAFCLALLRNL 417
Query: 388 PAVHPIFKLLVAHVRFTIAINTKAREQLICECGLFDKANATGGGGHVQMVQRAMKDLTYA 447
P HP++KLL+ H R+T+ IN+ R L+ E GL K + G G ++ RA+ +LTY
Sbjct: 418 PMCHPLYKLLIPHTRYTVQINSIGRAVLLNEGGLSAKGMSLGVEGFAGVMVRALSELTYD 477
Query: 448 SLCFPEAIKARGMESKEDIPYYFYRDDGLLVWEAIRTFTAEVVDIYYEGDQVVEEDPELQ 507
SL P RG+ +D+P Y+YRDD L VW A+ + E++ YY D VE DPELQ
Sbjct: 478 SLYLPNDFVERGV---QDLPGYYYRDDSLAVWNALEKYVTEIITYYYPSDAAVEGDPELQ 534
Query: 508 DFVNDVYVYGMRGRKSSGFPKSVKSREQLSEYLTVVIFTASAQHAAVNFGQYDWCSWIPN 567
+V +++ + GR+SSGFP+ +++ +L Y+T+VI+T SA+HAAVN GQ ++ +W+PN
Sbjct: 535 SWVQEIFKECLLGRESSGFPRCLRTVPELIRYVTIVIYTCSAKHAAVNTGQMEFTAWMPN 594
Query: 568 APPTMRAPPPTAKGVVTIEQIVDTLPDRGRSCWHLGAVWALSQFQENELFLGMYPEEHFI 627
P +MR PP KG+ T+E +DTLPD +C L +W LS+ ++ LG +P+ HF+
Sbjct: 595 FPASMRNPPIQTKGLTTLETFMDTLPDVKTTCITLLVLWTLSREPDDRRPLGHFPDIHFV 654
Query: 628 EKPVKEAMARFRKNLEAIVSVIAERNKKKQLPYYYLSPDRIPNSVAI 674
E+ + ++ FR+ L I I +RNK +PYYYL P I NS++I
Sbjct: 655 EEAPRRSIEAFRQRLNQISHDIRQRNKCLPIPYYYLDPVLIENSISI 701
>gi|154426292 arachidonate 12-lipoxygenase [Homo sapiens]
Length = 663
Score = 522 bits (1344), Expect = e-148
Identities = 282/678 (41%), Positives = 411/678 (60%), Gaps = 19/678 (2%)
Query: 1 MPSYTVTVATGSQWFAGTDDYIYLSLVGSAGCSEKHLLDKPFYNDFERGAVDSYDVTVDE 60
M Y + VATG+ F+G+ + + L LVG+ G +E L +P RG + +D V E
Sbjct: 1 MGRYRIRVATGAWLFSGSYNRVQLWLVGTRGEAELELQLRP-----ARGEEEEFDHDVAE 55
Query: 61 ELGEIQLVRIEKRKYWLNDDWYLKYITLKTPHG-DYIEFPCYRWITGDVEVVLRDGRAKL 119
+LG +Q VR+ K + ++D W+ IT++ P + FPCYRW+ G+ + L +G A+L
Sbjct: 56 DLGLLQFVRLRKHHWLVDDAWFCDRITVQGPGACAEVAFPCYRWVQGEDILSLPEGTARL 115
Query: 120 ARDDQIHILKQHRRKELETRQKQYRWMEWNPGFPLSIDAKCHKDLPRDIQFDSEKGVDFV 179
D+ + + ++HR KEL+ RQ+ Y W W G PL+I A DLP +++F EK +DF
Sbjct: 116 PGDNALDMFQKHREKELKDRQQIYCWATWKEGLPLTIAADRKDDLPPNMRFHEEKRLDFE 175
Query: 180 LNYSKAMENLFINRFMHMFQSSWNDFADFEKIFVKISNTISERVMNHWQEDLMFGYQFLN 239
+ + R ++ SSWN DF++IF + ++E+V WQ+D +F YQFLN
Sbjct: 176 WTLKAGALEMALKR-VYTLLSSWNCLEDFDQIFWGQKSALAEKVRQCWQDDELFSYQFLN 234
Query: 240 GCNPVLIRRCTELPEKLPVTTEMVECSLERQLSLEQEVQQGNIFIVDFELLDGIDANKTD 299
G NP+L+RR T LP +L + + M E Q LE+E+Q G++F DF LLDGI AN
Sbjct: 235 GANPMLLRRSTSLPSRLVLPSGMEEL----QAQLEKELQNGSLFEADFILLDGIPANVIR 290
Query: 300 PCTLQFLAAPICLLYKNLANKIVPIAIQLNQIPGDENP---IFLPSDAKYDWLLAKIWVR 356
Q+LAAP+ +L K+ P+ IQ+ Q P +P +FLPSD WLLAK WVR
Sbjct: 291 G-EKQYLAAPLVMLKMEPNGKLQPMVIQI-QPPNPSSPTPTLFLPSDPPLAWLLAKSWVR 348
Query: 357 SSDFHVHQTITHLLRTHLVSEVFGIAMYRQLPAVHPIFKLLVAHVRFTIAINTKAREQLI 416
+SDF +H+ HLL THLV+EV +A R LP +HPIFK L+ H+R+T+ INT+AR QLI
Sbjct: 349 NSDFQLHEIQYHLLNTHLVAEVIAVATMRCLPGLHPIFKFLIPHIRYTMEINTRARTQLI 408
Query: 417 CECGLFDKANATGGGGHVQMVQRAMKDLTYASLCFPEAIKARGMESKEDIPYYFYRDDGL 476
+ G+FDKA +TGGGGHVQ+++RA LTY SLC P+ + RG+ +P Y D L
Sbjct: 409 SDGGIFDKAVSTGGGGHVQLLRRAAAQLTYCSLCPPDDLADRGLLG---LPGALYAHDAL 465
Query: 477 LVWEAIRTFTAEVVDIYYEGDQVVEEDPELQDFVNDVYVYGMRGRKSSGFPKSVKSREQL 536
+WE I + +V ++Y+ D +V+ DPELQ + ++ G+ + GFP S +S+ QL
Sbjct: 466 RLWEIIARYVEGIVHLFYQRDDIVKGDPELQAWCREITEVGLCQAQDRGFPVSFQSQSQL 525
Query: 537 SEYLTVVIFTASAQHAAVNFGQYDWCSWIPNAPPTMRAPPPTAKGVVTIEQIVDTLPDRG 596
+LT+ +FT +AQHAA+N GQ DW +W+PNAP TMR PPPT K VT+ ++ +LPD
Sbjct: 526 CHFLTMCVFTCTAQHAAINQGQLDWYAWVPNAPCTMRMPPPTTKEDVTMATVMGSLPDVR 585
Query: 597 RSCWHLGAVWALSQFQENELFLGMYPEEHFIEKPVKEAMARFRKNLEAIVSVIAERNKKK 656
++C + W LS+ Q + + LG + E++F K + +FR +LE + I RN++
Sbjct: 586 QACLQMAISWHLSRRQPDMVPLGHHKEKYFSGPKPKAVLNQFRTDLEKLEKEITARNEQL 645
Query: 657 QLPYYYLSPDRIPNSVAI 674
PY YL P I NSV I
Sbjct: 646 DWPYEYLKPSCIENSVTI 663
>gi|182765464 arachidonate lipoxygenase 3 [Homo sapiens]
Length = 711
Score = 518 bits (1333), Expect = e-147
Identities = 279/720 (38%), Positives = 406/720 (56%), Gaps = 55/720 (7%)
Query: 1 MPSYTVTVATGSQWFAGTDDYIYLSLVGSAGCSEKHLLDKPFYNDFERGAVDSYDVTVDE 60
M Y + V TG AGT D I ++LVG+ G S K LD+ DF G+V Y V
Sbjct: 1 MAVYRLCVTTGPYLRAGTLDNISVTLVGTCGESPKQRLDR-MGRDFAPGSVQKYKVRCTA 59
Query: 61 ELGEIQLVRIEKRKY--WLNDDWYLKYITLKTPHGDYIEFPCYRWITGDVEVVLRDGRAK 118
ELGE+ L+R+ K +Y + D WY I + P G FPCY+WI G V LR G A+
Sbjct: 60 ELGELLLLRVHKERYAFFRKDSWYCSRICVTEPDGSVSHFPCYQWIEGYCTVELRPGTAR 119
Query: 119 LARDDQIHILKQHRRKELETRQKQYRWMEWNPGFPLSIDAKCHKDLPRD----------- 167
D + +L HR +EL RQ+ YRW + PGFP +D +++ D
Sbjct: 120 TICQDSLPLLLDHRTRELRARQECYRWKIYAPGFPCMVDVNSFQEMESDKKFALTKTTTC 179
Query: 168 ------------------------------IQFDSEKGVDFVLNYSKAMENLFINRFMHM 197
+++ + K + + N A + + +
Sbjct: 180 VDQGDSSGNRYLPGFPMKIDIPSLMYMEPNVRYSATKTISLLFNAIPASLGMKLRGLLDR 239
Query: 198 FQSSWNDFADFEKIFVKISNTISERVMNHWQEDLMFGYQFLNGCNPVLIRRCTELPEKLP 257
+ SW D + IF ++ V HW ED FGYQ+LNG NPV++ + LP KLP
Sbjct: 240 -KGSWKKLDDMQNIFWCHKTFTTKYVTEHWCEDHFFGYQYLNGVNPVMLHCISSLPSKLP 298
Query: 258 VTTEMVECSLERQLSLEQEVQQGNIFIVDFELLDGIDANKTDPCT---LQFLAAPICLLY 314
VT +MV L + L+ E+++GNIF+ D+ +L A C Q++AAP+CLL+
Sbjct: 299 VTNDMVAPLLGQDTCLQTELERGNIFLADYWIL----AEAPTHCLNGRQQYVAAPLCLLW 354
Query: 315 KNLANKIVPIAIQLNQIPGDENPIFLPSDAKYDWLLAKIWVRSSDFHVHQTITHLLRTHL 374
+ +VP+AIQL+Q PG ++PIFLP+D+++DWLLAK WVR+S+F VH+ TH L THL
Sbjct: 355 LSPQGALVPLAIQLSQTPGPDSPIFLPTDSEWDWLLAKTWVRNSEFLVHENNTHFLCTHL 414
Query: 375 VSEVFGIAMYRQLPAVHPIFKLLVAHVRFTIAINTKAREQLICECGLFDKANATGGGGHV 434
+ E F +A RQLP HPI+KLL+ H R+T+ +NT AR L+ GL D+ + G G +
Sbjct: 415 LCEAFAMATLRQLPLCHPIYKLLLPHTRYTLQVNTIARATLLNPEGLVDQVTSIGRQGLI 474
Query: 435 QMVQRAMKDLTYASLCFPEAIKARGMESKEDIPYYFYRDDGLLVWEAIRTFTAEVVDIYY 494
++ + TY + C P++++ARG+ + IP Y YRDDGL +W AI +F +E+V YY
Sbjct: 475 YLMSTGLAHFTYTNFCLPDSLRARGVLA---IPNYHYRDDGLKIWAAIESFVSEIVGYYY 531
Query: 495 EGDQVVEEDPELQDFVNDVYVYGMRGRKSSGFPKSVKSREQLSEYLTVVIFTASAQHAAV 554
D V++D ELQ + +++ GR+SSGFP + + ++ ++LT +IF SAQHAAV
Sbjct: 532 PSDASVQQDSELQAWTGEIFAQAFLGRESSGFPSRLCTPGEMVKFLTAIIFNCSAQHAAV 591
Query: 555 NFGQYDWCSWIPNAPPTMRAPPPTAKGVVTIEQIVDTLPDRGRSCWHLGAVWALSQFQEN 614
N GQ+D+ +W+PNAP +MR PPP KG T++ +DTLP+ SC +L W +SQ ++
Sbjct: 592 NSGQHDFGAWMPNAPSSMRQPPPQTKGTTTLKTYLDTLPEVNISCNNLLLFWLVSQEPKD 651
Query: 615 ELFLGMYPEEHFIEKPVKEAMARFRKNLEAIVSVIAERNKKKQLPYYYLSPDRIPNSVAI 674
+ LG YP+EHF E+ + ++A F+ L I I ERN+ LPY YL P I NSV+I
Sbjct: 652 QRPLGTYPDEHFTEEAPRRSIAAFQSRLAQISRDIQERNQGLALPYTYLDPPLIENSVSI 711
>gi|85067499 arachidonate 15-lipoxygenase, second type isoform a
[Homo sapiens]
Length = 647
Score = 516 bits (1330), Expect = e-146
Identities = 274/682 (40%), Positives = 407/682 (59%), Gaps = 43/682 (6%)
Query: 1 MPSYTVTVATGSQWFAGTDDYIYLSLVGSAGCSEKHLLDKPFYNDFERGAVDSYDVTVDE 60
M + V V+TG + AGT D + +S+VG+ G S LD +F GA + + VT+ E
Sbjct: 1 MAEFRVRVSTGEAFGAGTWDKVSVSIVGTRGESPPLPLDN-LGKEFTAGAEEDFQVTLPE 59
Query: 61 ELGEIQLVRIEKRKYWLN-------DDWYLKYITLKTPHGDYIEFPCYRWITGDVEVVLR 113
++G + L+R+ K L D W+ ++ L P G ++ FPCY+W+ G +VL+
Sbjct: 60 DVGRVLLLRVHKAPPVLPLLGPLAPDAWFCRWFQLTPPRGGHLLFPCYQWLEGAGTLVLQ 119
Query: 114 DGRAKLARDDQIHILKQHRRKELETRQKQYRWMEWNPGFPLSIDAKCHKDLPRDIQFDSE 173
+G AK++ D +L+Q R++EL+ RQ+ Y+W +NPG+P +D K +DL +I++ +
Sbjct: 120 EGTAKVSWADHHPVLQQQRQEELQARQEMYQWKAYNPGWPHCLDEKTVEDLELNIKYSTA 179
Query: 174 KGVDFVLNYSKAMENLFINRFMHMFQSSWNDFADFEKIFVKISNTISERVMNHWQEDLMF 233
K +F L A + I + + W + ++IF +E HWQED F
Sbjct: 180 KNANFYLQAGSAFAEMKIKGLLDR-KGLWRSLNEMKRIFNFRRTPAAEHAFEHWQEDAFF 238
Query: 234 GYQFLNGCNPVLIRRCTELPEKLPVTTEMVECSLERQLSLEQEVQQGNIFIVDFELLDGI 293
QFLNG NPVLIRRC LP+ PVT MV L SL+ E+++G++F+VD +L GI
Sbjct: 239 ASQFLNGLNPVLIRRCHYLPKNFPVTDAMVASVLGPGTSLQAELEKGSLFLVDHGILSGI 298
Query: 294 DANKTDPCTLQFLAAPICLLYKNLA-NKIVPIAIQLNQIPGDENPIFLPSDAKYDWLLAK 352
N + QF AAP+ LLY++ ++P+AIQL+Q PG +PIFLP+D K+DWLLAK
Sbjct: 299 QTNVINGKP-QFSAAPMTLLYQSPGCGPLLPLAIQLSQTPGPNSPIFLPTDDKWDWLLAK 357
Query: 353 IWVRSSDFHVHQTITHLLRTHLVSEVFGIAMYRQLPAVHPIFKLLVAHVRFTIAINTKAR 412
WVR+++F H+ +THLL +HL+ EVF +A RQLP HP+FK
Sbjct: 358 TWVRNAEFSFHEALTHLLHSHLLPEVFTLATLRQLPHCHPLFK----------------- 400
Query: 413 EQLICECGLFDKANATGGGGHVQMVQRAMKDLTYASLCFPEAIKARGMESKEDIPYYFYR 472
+ G G +++QR MK L Y+ LC PE I+ RG+E DIP Y+YR
Sbjct: 401 ------------STGIGIEGFSELIQRNMKQLNYSLLCLPEDIRTRGVE---DIPGYYYR 445
Query: 473 DDGLLVWEAIRTFTAEVVDIYYEGDQVVEEDPELQDFVNDVYVYGMRGRKSSGFPKSVKS 532
DDG+ +W A+ F +E++ IYY D+ V++D ELQ +V +++ G ++SSG P S+++
Sbjct: 446 DDGMQIWGAVERFVSEIIGIYYPSDESVQDDRELQAWVREIFSKGFLNQESSGIPSSLET 505
Query: 533 REQLSEYLTVVIFTASAQHAAVNFGQYDWCSWIPNAPPTMRAPPPTAKGVVTIEQIVDTL 592
RE L +Y+T+VIFT SA+HAAV+ GQ+D C+W+PN PP+M+ PPPT+KG+ T E + TL
Sbjct: 506 REALVQYVTMVIFTCSAKHAAVSAGQFDSCAWMPNLPPSMQLPPPTSKGLATCEGFIATL 565
Query: 593 PDRGRSCWHLGAVWALSQFQENELFLGMYPEEHFIEKPVKEAMARFRKNLEAIVSVIAER 652
P +C + A+W LS+ ++ LG YP+EHF E+ + ++A F+ L I I ER
Sbjct: 566 PPVNATCDVILALWLLSKEPGDQRPLGTYPDEHFTEEAPRRSIATFQSRLAQISRGIQER 625
Query: 653 NKKKQLPYYYLSPDRIPNSVAI 674
N+ LPY YL P I NSV+I
Sbjct: 626 NQGLVLPYTYLDPPLIENSVSI 647
>gi|40316937 arachidonate 15-lipoxygenase [Homo sapiens]
Length = 662
Score = 499 bits (1284), Expect = e-141
Identities = 269/678 (39%), Positives = 409/678 (60%), Gaps = 20/678 (2%)
Query: 1 MPSYTVTVATGSQWFAGTDDYIYLSLVGSAGCSEKHLLDKPFYNDFERGAVDSYDVTVDE 60
M Y + V+TG+ +AG+++ + L LVG G + L K + RG V V E
Sbjct: 1 MGLYRIRVSTGASLYAGSNNQVQLWLVGQHG---EAALGKRLWP--ARGKETELKVEVPE 55
Query: 61 ELGEIQLVRIEKRKYWLNDDWYLKYITLKTPH-GDYIEFPCYRWITGDVEVVLRDGRAKL 119
LG + V++ KR +D W+ +I+++ P GD + FPCYRW+ G+ + L +G +
Sbjct: 56 YLGPLLFVKLRKRHLLKDDAWFCNWISVQGPGAGDEVRFPCYRWVEGNGVLSLPEGTGRT 115
Query: 120 ARDDQIHILKQHRRKELETRQKQYRWMEWNPGFPLSIDAKCHKDLPRDIQFDSEKGVDFV 179
+D + ++HR +ELE R+K YRW W G L++ DLP D +F +K VDF
Sbjct: 116 VGEDPQGLFQKHREEELEERRKLYRWGNWKDGLILNMAGAKLYDLPVDERFLEDKRVDFE 175
Query: 180 LNYSKAMENLFINRFMHMFQSSWNDFADFEKIFVKISNTISERVMNHWQEDLMFGYQFLN 239
++ +K + +L I +++ + W D DF +IF + ++ERV + W+ED +FGYQFLN
Sbjct: 176 VSLAKGLADLAIKDSLNVL-TCWKDLDDFNRIFWCGQSKLAERVRDSWKEDALFGYQFLN 234
Query: 240 GCNPVLIRRCTELPEKLPVTTEMVECSLERQLSLEQEVQQGNIFIVDFELLDGIDANKTD 299
G NPV++RR LP +L M E Q LE+E++ G +F DF LLDGI AN
Sbjct: 235 GANPVVLRRSAHLPARLVFPPGMEEL----QAQLEKELEGGTLFEADFSLLDGIKANVI- 289
Query: 300 PCTLQFLAAPICLLYKNLANKIVPIAIQLNQIPGDENP---IFLPSDAKYDWLLAKIWVR 356
C+ Q LAAP+ +L K++P+ IQL Q+P +P +FLP+D WLLAK WVR
Sbjct: 290 LCSQQHLAAPLVMLKLQPDGKLLPMVIQL-QLPRTGSPPPPLFLPTDPPMAWLLAKCWVR 348
Query: 357 SSDFHVHQTITHLLRTHLVSEVFGIAMYRQLPAVHPIFKLLVAHVRFTIAINTKAREQLI 416
SSDF +H+ +HLLR HL++EV +A R LP++HPIFKL++ H+R+T+ IN +AR L+
Sbjct: 349 SSDFQLHELQSHLLRGHLMAEVIVVATMRCLPSIHPIFKLIIPHLRYTLEINVRARTGLV 408
Query: 417 CECGLFDKANATGGGGHVQMVQRAMKDLTYASLCFPEAIKARGMESKEDIPYYFYRDDGL 476
+ G+FD+ +TGGGGHVQ++++A LTY+S C P+ + RG+ + FY D L
Sbjct: 409 SDMGIFDQIMSTGGGGHVQLLKQAGAFLTYSSFCPPDDLADRGLLG---VKSSFYAQDAL 465
Query: 477 LVWEAIRTFTAEVVDIYYEGDQVVEEDPELQDFVNDVYVYGMRGRKSSGFPKSVKSREQL 536
+WE I + +V ++Y+ D V++DPELQ + ++ G++G + GFP S+++R+Q+
Sbjct: 466 RLWEIIYRYVEGIVSLHYKTDVAVKDDPELQTWCREITEIGLQGAQDRGFPVSLQARDQV 525
Query: 537 SEYLTVVIFTASAQHAAVNFGQYDWCSWIPNAPPTMRAPPPTAKGVVTIEQIVDTLPDRG 596
++T+ IFT + QHA+V+ GQ DW SW+PNAP TMR PPPT K T+E ++ TLP+
Sbjct: 526 CHFVTMCIFTCTGQHASVHLGQLDWYSWVPNAPCTMRLPPPTTKD-ATLETVMATLPNFH 584
Query: 597 RSCWHLGAVWALSQFQENELFLGMYPEEHFIEKPVKEAMARFRKNLEAIVSVIAERNKKK 656
++ + W L + Q + +G + EE+F K + +FR+ L A+ I RN K
Sbjct: 585 QASLQMSITWQLGRRQPVMVAVGQHEEEYFSGPEPKAVLKKFREELAALDKEIEIRNAKL 644
Query: 657 QLPYYYLSPDRIPNSVAI 674
+PY YL P + NSVAI
Sbjct: 645 DMPYEYLRPSVVENSVAI 662
>gi|85067503 arachidonate 15-lipoxygenase, second type isoform b
[Homo sapiens]
Length = 602
Score = 460 bits (1183), Expect = e-129
Identities = 258/682 (37%), Positives = 378/682 (55%), Gaps = 88/682 (12%)
Query: 1 MPSYTVTVATGSQWFAGTDDYIYLSLVGSAGCSEKHLLDKPFYNDFERGAVDSYDVTVDE 60
M + V V+TG + AGT D + +S+VG+ G S LD +F GA + + VT+ E
Sbjct: 1 MAEFRVRVSTGEAFGAGTWDKVSVSIVGTRGESPPLPLDN-LGKEFTAGAEEDFQVTLPE 59
Query: 61 ELGEIQLVRIEKRKYWLN-------DDWYLKYITLKTPHGDYIEFPCYRWITGDVEVVLR 113
++G + L+R+ K L D W+ ++ L P G ++ FPCY+W+ G +VL+
Sbjct: 60 DVGRVLLLRVHKAPPVLPLLGPLAPDAWFCRWFQLTPPRGGHLLFPCYQWLEGAGTLVLQ 119
Query: 114 DGRAKLARDDQIHILKQHRRKELETRQKQYRWMEWNPGFPLSIDAKCHKDLPRDIQFDSE 173
+G AK++ D +L+Q R++EL+ RQ+ Y+W +NPG+P +D K +DL +I++ +
Sbjct: 120 EGTAKVSWADHHPVLQQQRQEELQARQEMYQWKAYNPGWPHCLDEKTVEDLELNIKYSTA 179
Query: 174 KGVDFVLNYSKAMENLFINRFMHMFQSSWNDFADFEKIFVKISNTISERVMNHWQEDLMF 233
K +F L A + I + + W + ++IF +E HWQED F
Sbjct: 180 KNANFYLQAGSAFAEMKIKGLLDR-KGLWRSLNEMKRIFNFRRTPAAEHAFEHWQEDAFF 238
Query: 234 GYQFLNGCNPVLIRRCTELPEKLPVTTEMVECSLERQLSLEQEVQQGNIFIVDFELLDGI 293
QFLNG NPVLIRRC LP+ PVT MV L SL+ E+++G++F+VD +L GI
Sbjct: 239 ASQFLNGLNPVLIRRCHYLPKNFPVTDAMVASVLGPGTSLQAELEKGSLFLVDHGILSGI 298
Query: 294 DANKTDPCTLQFLAAPICLLYKNLA-NKIVPIAIQLNQIPGDENPIFLPSDAKYDWLLAK 352
N + QF AAP+ LLY++ ++P+AIQL+Q PG +PIFLP+D K+DWLLAK
Sbjct: 299 QTNVINGKP-QFSAAPMTLLYQSPGCGPLLPLAIQLSQTPGPNSPIFLPTDDKWDWLLAK 357
Query: 353 IWVRSSDFHVHQTITHLLRTHLVSEVFGIAMYRQLPAVHPIFKLLVAHVRFTIAINTKAR 412
WVR+++F H+ +THLL +HL+ EVF +A RQLP HP+FK
Sbjct: 358 TWVRNAEFSFHEALTHLLHSHLLPEVFTLATLRQLPHCHPLFK----------------- 400
Query: 413 EQLICECGLFDKANATGGGGHVQMVQRAMKDLTYASLCFPEAIKARGMESKEDIPYYFYR 472
+ G G +++QR MK L Y+ LC PE I+ RG+ EDIP Y+YR
Sbjct: 401 ------------STGIGIEGFSELIQRNMKQLNYSLLCLPEDIRTRGV---EDIPGYYYR 445
Query: 473 DDGLLVWEAIRTFTAEVVDIYYEGDQVVEEDPELQDFVNDVYVYGMRGRKSSGFPKSVKS 532
DDG+ +W G P S+++
Sbjct: 446 DDGMQIW---------------------------------------------GIPSSLET 460
Query: 533 REQLSEYLTVVIFTASAQHAAVNFGQYDWCSWIPNAPPTMRAPPPTAKGVVTIEQIVDTL 592
RE L +Y+T+VIFT SA+HAAV+ GQ+D C+W+PN PP+M+ PPPT+KG+ T E + TL
Sbjct: 461 REALVQYVTMVIFTCSAKHAAVSAGQFDSCAWMPNLPPSMQLPPPTSKGLATCEGFIATL 520
Query: 593 PDRGRSCWHLGAVWALSQFQENELFLGMYPEEHFIEKPVKEAMARFRKNLEAIVSVIAER 652
P +C + A+W LS+ ++ LG YP+EHF E+ + ++A F+ L I I ER
Sbjct: 521 PPVNATCDVILALWLLSKEPGDQRPLGTYPDEHFTEEAPRRSIATFQSRLAQISRGIQER 580
Query: 653 NKKKQLPYYYLSPDRIPNSVAI 674
N+ LPY YL P I NSV+I
Sbjct: 581 NQGLVLPYTYLDPPLIENSVSI 602
>gi|5174633 receptor for egg jelly-like protein precursor [Homo
sapiens]
Length = 2253
Score = 65.5 bits (158), Expect = 2e-10
Identities = 31/105 (29%), Positives = 57/105 (54%), Gaps = 1/105 (0%)
Query: 4 YTVTVATGSQWFAGTDDYIYLSLVGSAGCSEKHLLDKPFYNDFERGAVDSYDVTVDEELG 63
Y VT+ TGS+W +GT +++ L G+ S+ H L P + RG+++++ +T +LG
Sbjct: 1232 YLVTIFTGSRWGSGTRANVFVQLRGTVSTSDVHCLSHPHFTTLYRGSINTFLLTTKSDLG 1291
Query: 64 EIQLVRIEKRKYWLNDDWYLKYITLKTPHGDYI-EFPCYRWITGD 107
+I +R+ + WYL I ++ +I F C +W++ D
Sbjct: 1292 DIHSIRVWHNNEGRSPSWYLSRIKVENLFSRHIWLFICQKWLSVD 1336
>gi|239050813 lipoxygenase homology domains 1 isoform 1 [Homo
sapiens]
Length = 2211
Score = 59.3 bits (142), Expect = 1e-08
Identities = 39/105 (37%), Positives = 53/105 (50%), Gaps = 5/105 (4%)
Query: 4 YTVTVATGSQWFAGTDDYIYLSLVGSAGCSEKHLLDKPFYNDFERGAVDSYDVTVDEELG 63
Y V ATG AGTD ++++L G G S K L + FE+G VD + V + +G
Sbjct: 45 YEVVTATGDVRGAGTDANVFITLFGENGLSPKLQLTSKSKSAFEKGNVDVFRVRTN-NVG 103
Query: 64 EIQLVRIEKRKYWLNDDWYLKYI---TLKTPHGDYIEFPCYRWIT 105
I VRIE LN WYL ++ +K PH Y F C W++
Sbjct: 104 LIYKVRIEHDNTGLNASWYLDHVIVTDMKRPHLRYY-FNCNNWLS 147
Score = 58.5 bits (140), Expect = 2e-08
Identities = 38/112 (33%), Positives = 52/112 (46%), Gaps = 6/112 (5%)
Query: 1 MPSYTVTVATGSQWFAGTDDYIYLSLVGSAGCSEKHLLDKPFYND--FERGAVDSYDVTV 58
M Y VTV TG AGTD +YL L G G + + LL N FE+G D + +
Sbjct: 552 MARYHVTVCTGELEGAGTDANVYLCLFGDVGDTGERLLYNCRNNTDLFEKGNADEFTIE- 610
Query: 59 DEELGEIQLVRIEKRKYWLNDDWYLKYITLK---TPHGDYIEFPCYRWITGD 107
+ ++ VRI WYL + ++ P D +EFPC RW+ D
Sbjct: 611 SVTMRNVRRVRIRHDGKGSGSGWYLDRVLVREEGQPESDNVEFPCLRWLDKD 662
Score = 51.2 bits (121), Expect = 3e-06
Identities = 33/102 (32%), Positives = 53/102 (51%), Gaps = 2/102 (1%)
Query: 4 YTVTVATGSQWFAGTDDYIYLSLVGSAGCSEKHLLDKPFYNDFERGAVDSYDVTVDEELG 63
Y V V TG + AGTD +++++ G+ G + K L + N FERG+ D + + ELG
Sbjct: 2094 YEVIVTTGYEPGAGTDANVFVTIFGANGDTGKRELKQKMRNLFERGSTDRFFLET-LELG 2152
Query: 64 EIQLVRIEKRKYWLNDDWYLKYITL-KTPHGDYIEFPCYRWI 104
E++ VR+E W ++ + + T G F C RW+
Sbjct: 2153 ELRKVRLEHDSSGYCSGWLVEKVEVTNTSTGVATIFNCGRWL 2194
Score = 47.4 bits (111), Expect = 4e-05
Identities = 31/106 (29%), Positives = 58/106 (54%), Gaps = 6/106 (5%)
Query: 3 SYTVTVATGSQWFAGTDDYIYLSLVGSAGCSEKHLL--DKPFYNDFERGAVDSYDV-TVD 59
+++VT+ TG + AGTD ++++L G+ + LL K + FER +++ + V T+D
Sbjct: 1176 TFSVTIKTGVKKNAGTDANVFITLFGTQDDTGMTLLKSSKTNSDKFERDSIEIFTVETLD 1235
Query: 60 EELGEIQLVRIEKRKYWLNDDWYLKYITLKTPH-GDYIEFPCYRWI 104
LG++ VR+ W++ ++ + P G + FPC RW+
Sbjct: 1236 --LGDLWKVRLGHDNTGKAPGWFVDWVEVDAPSLGKCMTFPCGRWL 1279
Score = 47.0 bits (110), Expect = 6e-05
Identities = 37/133 (27%), Positives = 62/133 (46%), Gaps = 10/133 (7%)
Query: 3 SYTVTVATGSQWFAGTDDYIYLSLVGS--AGCSEKHLLDKPFYNDFERGAVDSYDVTVDE 60
+Y V V TG+ AGTD +YL++ G E+ L N FE+G D++ +
Sbjct: 1023 TYEVQVVTGNVPKAGTDANVYLTIYGEEYGDTGERPLKKSDKSNKFEQGQTDTFTIYA-I 1081
Query: 61 ELGEIQLVRIEKRKYWLNDDWYLKYITLKTPHGDY-IEFPCYRWITGDVEVVLRDGR--A 117
+LG + +RI W+L I + + + FPC RW+ + + DG+
Sbjct: 1082 DLGALTKIRIRHDNTGNRAGWFLDRIDITDMNNEITYYFPCQRWLAVEED----DGQLSR 1137
Query: 118 KLARDDQIHILKQ 130
+L D+ ++L Q
Sbjct: 1138 ELLPVDESYVLPQ 1150
Score = 46.6 bits (109), Expect = 8e-05
Identities = 30/105 (28%), Positives = 53/105 (50%), Gaps = 4/105 (3%)
Query: 4 YTVTVATGSQWFAGTDDYIYLSLVGSAGCSEKHLLDKP--FYNDFERGAVDSYDVTVDEE 61
Y+V + TG+ AGTD +Y+++ G G + + L K N FERG D++ + +
Sbjct: 1462 YSVQIFTGNIPGAGTDAKVYITIYGDLGDTGERYLGKSENRTNKFERGTADTFIIEA-AD 1520
Query: 62 LGEIQLVRIEKRKYWLNDDWYLKYITL-KTPHGDYIEFPCYRWIT 105
LG I +++ DWY++ + + + D F C RW++
Sbjct: 1521 LGVIYKIKLRHDNSKWCADWYVEKVEIWNDTNEDEFLFLCGRWLS 1565
Score = 45.1 bits (105), Expect = 2e-04
Identities = 40/149 (26%), Positives = 64/149 (42%), Gaps = 18/149 (12%)
Query: 3 SYTVTVATGSQWFAGTDDYIYLSLVGSAG--CSEKHLLDKPFYNDFERGAVDSYDVTVDE 60
+Y VTV TG AGT IYL + G+ G S K L+ F+RG D + + +
Sbjct: 297 TYIVTVFTGDVRGAGTKSKIYLVMYGARGNKNSGKIFLEG---GVFDRGRTDIFHIELAV 353
Query: 61 ELGEIQLVRIEKRKYWLNDDWYLKYITLKTPH-GDYIEFPCYRWITGDVEVVLRDGRAKL 119
L + V + +N W+ + + + P G FPC W L + +A
Sbjct: 354 LLSPLSRVSVGHGNVGVNRGWFCEKVVILCPFTGIQQTFPCSNW--------LDEKKADG 405
Query: 120 ARDDQIHILKQHRRKELETRQKQYRWMEW 148
+ Q++ + R+K L K++ W W
Sbjct: 406 LIERQLYEMVSLRKKRL----KKFPWSLW 430
Score = 44.7 bits (104), Expect = 3e-04
Identities = 29/105 (27%), Positives = 48/105 (45%), Gaps = 5/105 (4%)
Query: 4 YTVTVATGSQWFAGTDDYIYLSLVGSAGCSEKHLL---DKPFYNDFERGAVDSYDVTVDE 60
Y +++ TG A TD +Y+ L G + K +L D + FERG VD + +
Sbjct: 686 YHISLKTGDVSGASTDSRVYIKLYGDKSDTIKQVLLVSDNNLKDYFERGRVDEFTLET-L 744
Query: 61 ELGEIQLVRIEKRKYWLNDDWYLKYITLKTP-HGDYIEFPCYRWI 104
+G I + I ++ W+L + ++ P G FP RW+
Sbjct: 745 NIGNINRLVIGHDSTGMHASWFLGSVQIRVPRQGKQYTFPANRWL 789
Score = 43.9 bits (102), Expect = 5e-04
Identities = 32/114 (28%), Positives = 52/114 (45%), Gaps = 5/114 (4%)
Query: 3 SYTVTVATGSQWFAGTDDYIYLSLVGSAGCSEKHLLDKPF-YNDFERGAVDSYDVTVDEE 61
SYTV V T AGTD +++ + G G S L + +N FER D+++
Sbjct: 1824 SYTVAVKTSDILGAGTDANVFIIIFGENGDSGTLALKQSANWNKFERNNTDTFNFPDMLS 1883
Query: 62 LGEIQLVRIEKRKYWLNDDWYLKYITLK-TPHGDYIEFPCYRWIT---GDVEVV 111
LG + +R+ + W+L Y+ +K + F C W++ GD + V
Sbjct: 1884 LGHLCKLRVWHDNKGIFPGWHLSYVDVKDNSRDETFHFQCDCWLSKSEGDGQTV 1937
Score = 42.0 bits (97), Expect = 0.002
Identities = 34/114 (29%), Positives = 57/114 (50%), Gaps = 17/114 (14%)
Query: 4 YTVTVATGSQWFAGTDDYIYLSLVG-SAGCSEKHLL------DKPFYNDFERGAVDSYDV 56
Y +T+ T + AGTD I++ + G A C+++ L K F FER + + V
Sbjct: 1308 YEITLYTSDVFAAGTDANIFIIIYGCDAVCTQQKYLCTNKREQKQF---FERKSASRFIV 1364
Query: 57 TVDEELGEI-QLVRIEKRKYWLNDDWYLKYITLK--TPHGDYIE---FPCYRWI 104
+ E++GEI + +RI +N W+ ++ ++ P D E FPC RW+
Sbjct: 1365 EL-EDVGEIIEKIRIGHNNTGMNPGWHCSHVDIRRLLPDKDGAETLTFPCDRWL 1417
Score = 40.8 bits (94), Expect = 0.004
Identities = 32/120 (26%), Positives = 59/120 (49%), Gaps = 9/120 (7%)
Query: 4 YTVTVATGSQWFAGTDDYIYLSLVGSAGCSEKHLLDKPFYNDFERGAVDSYDVTVDEELG 63
Y V V TG AGTD +++++ G G + + L+ ++FE+GA D + + +LG
Sbjct: 174 YEVKVYTGDVIGAGTDADVFINIFGEYGDTGERRLENE-KDNFEKGAEDRF-ILDAPDLG 231
Query: 64 EIQLVRIEKRKYWLNDDWYLKYITLK-TPHGDYIEFPCYRWITGDVEVVLRDGRAKLARD 122
++ + + + W+L I ++ + +FP RW+ D + DG K+ RD
Sbjct: 232 QLMKINVGHNNKGGSAGWFLSQIVIEDIGNKRKYDFPLNRWLALDED----DG--KIQRD 285
Score = 38.9 bits (89), Expect = 0.016
Identities = 31/103 (30%), Positives = 50/103 (48%), Gaps = 3/103 (2%)
Query: 4 YTVTVATGSQWFAGTDDYIYLSLVGSAGCSEKHLLDKPFYNDFERGAVDSYDVTVDEELG 63
Y +TV TG GTD I+++L G G +E+ LDK FER D++ + + ++
Sbjct: 1698 YEMTVWTGDVVGGGTDSNIFMTLYGINGSTEEMQLDKKKAR-FEREQNDTFIMEI-LDIA 1755
Query: 64 EIQLVRIEKRKYWLNDDWYLKYITLKTPH-GDYIEFPCYRWIT 105
+RI +W+L+ I LK + GD F W++
Sbjct: 1756 PFTKMRIRIDGLGSRPEWFLERILLKNMNTGDLTMFYYGDWLS 1798
Score = 35.8 bits (81), Expect = 0.13
Identities = 32/142 (22%), Positives = 60/142 (42%), Gaps = 15/142 (10%)
Query: 4 YTVTVATGSQWFAGTDDYIYLSLVGSAGCSEKHLLDKPFYNDFERGAVDSYDVTVDEELG 63
Y V + TG AGT +Y+ + G G +E L FER + D++ + ++G
Sbjct: 816 YEVEIWTGDVGGAGTSARVYMQIYGEKGKTEVLFLSSR-SKVFERASKDTFQLEA-ADVG 873
Query: 64 EIQLVRIEKRKYWLNDDWYLKYITLKTPHGDYIEFPCYRWITGDVEVV-LRDGRAKLARD 122
E+ +R+ W++ + L+ + +V++ + R K +D
Sbjct: 874 EVYKLRLGHTGEGFGPSWFVDTVWLR------------HLVVREVDLTPEEEARKKKEKD 921
Query: 123 DQIHILKQHRRKELETRQKQYR 144
+LK+ R K R+K+ R
Sbjct: 922 KLRQLLKKERLKAKLQRKKKKR 943
>gi|224458290 lipoxygenase homology domains 1 isoform 3 [Homo
sapiens]
Length = 512
Score = 51.2 bits (121), Expect = 3e-06
Identities = 33/102 (32%), Positives = 53/102 (51%), Gaps = 2/102 (1%)
Query: 4 YTVTVATGSQWFAGTDDYIYLSLVGSAGCSEKHLLDKPFYNDFERGAVDSYDVTVDEELG 63
Y V V TG + AGTD +++++ G+ G + K L + N FERG+ D + + ELG
Sbjct: 395 YEVIVTTGYEPGAGTDANVFVTIFGANGDTGKRELKQKMRNLFERGSTDRFFLET-LELG 453
Query: 64 EIQLVRIEKRKYWLNDDWYLKYITL-KTPHGDYIEFPCYRWI 104
E++ VR+E W ++ + + T G F C RW+
Sbjct: 454 ELRKVRLEHDSSGYCSGWLVEKVEVTNTSTGVATIFNCGRWL 495
Score = 43.9 bits (102), Expect = 5e-04
Identities = 32/114 (28%), Positives = 52/114 (45%), Gaps = 5/114 (4%)
Query: 3 SYTVTVATGSQWFAGTDDYIYLSLVGSAGCSEKHLLDKPF-YNDFERGAVDSYDVTVDEE 61
SYTV V T AGTD +++ + G G S L + +N FER D+++
Sbjct: 125 SYTVAVKTSDILGAGTDANVFIIIFGENGDSGTLALKQSANWNKFERNNTDTFNFPDMLS 184
Query: 62 LGEIQLVRIEKRKYWLNDDWYLKYITLK-TPHGDYIEFPCYRWIT---GDVEVV 111
LG + +R+ + W+L Y+ +K + F C W++ GD + V
Sbjct: 185 LGHLCKLRVWHDNKGIFPGWHLSYVDVKDNSRDETFHFQCDCWLSKSEGDGQTV 238
Score = 36.6 bits (83), Expect = 0.078
Identities = 30/101 (29%), Positives = 49/101 (48%), Gaps = 3/101 (2%)
Query: 6 VTVATGSQWFAGTDDYIYLSLVGSAGCSEKHLLDKPFYNDFERGAVDSYDVTVDEELGEI 65
+TV TG GTD I+++L G G +E+ LDK FER D++ + + ++
Sbjct: 1 MTVWTGDVVGGGTDSNIFMTLYGINGSTEEMQLDKKKAR-FEREQNDTFIMEI-LDIAPF 58
Query: 66 QLVRIEKRKYWLNDDWYLKYITLKTPH-GDYIEFPCYRWIT 105
+RI +W+L+ I LK + GD F W++
Sbjct: 59 TKMRIRIDGLGSRPEWFLERILLKNMNTGDLTMFYYGDWLS 99
>gi|239754889 PREDICTED: similar to hCG2036697 [Homo sapiens]
Length = 1029
Score = 48.1 bits (113), Expect = 3e-05
Identities = 38/127 (29%), Positives = 59/127 (46%), Gaps = 10/127 (7%)
Query: 4 YTVTVATGSQWFAGTDDYIYLSLVGSAG-CSEKHLLDKPFYNDFERGAVDSYDVTVDEEL 62
Y V VATG W AGT +Y+S+ G G + L +F RG D++ + L
Sbjct: 43 YEVNVATGELWNAGTVANVYISIHGEKGDTGSRQLFRSKSSFNFLRGQTDTFFLEA-VHL 101
Query: 63 GEIQLVRIEKRKYWLNDDWYLKYITLKTPHGDY-IEFPCYRWI---TGDVEVVLRDGRAK 118
G++ + I + W+L + +K P +Y F C+RW+ D ++V R
Sbjct: 102 GDLCKIVIGHDGLGPGNGWFLDDVVIKDPTTNYEYAFFCHRWLDQGEDDCKIV----REL 157
Query: 119 LARDDQI 125
ARD+ I
Sbjct: 158 YARDNSI 164
>gi|239749428 PREDICTED: hypothetical protein XP_002347033 [Homo
sapiens]
Length = 1029
Score = 48.1 bits (113), Expect = 3e-05
Identities = 38/127 (29%), Positives = 59/127 (46%), Gaps = 10/127 (7%)
Query: 4 YTVTVATGSQWFAGTDDYIYLSLVGSAG-CSEKHLLDKPFYNDFERGAVDSYDVTVDEEL 62
Y V VATG W AGT +Y+S+ G G + L +F RG D++ + L
Sbjct: 43 YEVNVATGELWNAGTVANVYISIHGEKGDTGSRQLFRSKSSFNFLRGQTDTFFLEA-VHL 101
Query: 63 GEIQLVRIEKRKYWLNDDWYLKYITLKTPHGDY-IEFPCYRWI---TGDVEVVLRDGRAK 118
G++ + I + W+L + +K P +Y F C+RW+ D ++V R
Sbjct: 102 GDLCKIVIGHDGLGPGNGWFLDDVVIKDPTTNYEYAFFCHRWLDQGEDDCKIV----REL 157
Query: 119 LARDDQI 125
ARD+ I
Sbjct: 158 YARDNSI 164
>gi|239743562 PREDICTED: hypothetical protein XP_002342894 [Homo
sapiens]
Length = 1029
Score = 48.1 bits (113), Expect = 3e-05
Identities = 38/127 (29%), Positives = 59/127 (46%), Gaps = 10/127 (7%)
Query: 4 YTVTVATGSQWFAGTDDYIYLSLVGSAG-CSEKHLLDKPFYNDFERGAVDSYDVTVDEEL 62
Y V VATG W AGT +Y+S+ G G + L +F RG D++ + L
Sbjct: 43 YEVNVATGELWNAGTVANVYISIHGEKGDTGSRQLFRSKSSFNFLRGQTDTFFLEA-VHL 101
Query: 63 GEIQLVRIEKRKYWLNDDWYLKYITLKTPHGDY-IEFPCYRWI---TGDVEVVLRDGRAK 118
G++ + I + W+L + +K P +Y F C+RW+ D ++V R
Sbjct: 102 GDLCKIVIGHDGLGPGNGWFLDDVVIKDPTTNYEYAFFCHRWLDQGEDDCKIV----REL 157
Query: 119 LARDDQI 125
ARD+ I
Sbjct: 158 YARDNSI 164
>gi|224458288 lipoxygenase homology domains 1 isoform 2 [Homo
sapiens]
Length = 1114
Score = 47.4 bits (111), Expect = 4e-05
Identities = 31/106 (29%), Positives = 58/106 (54%), Gaps = 6/106 (5%)
Query: 3 SYTVTVATGSQWFAGTDDYIYLSLVGSAGCSEKHLL--DKPFYNDFERGAVDSYDV-TVD 59
+++VT+ TG + AGTD ++++L G+ + LL K + FER +++ + V T+D
Sbjct: 65 TFSVTIKTGVKKNAGTDANVFITLFGTQDDTGMTLLKSSKTNSDKFERDSIEIFTVETLD 124
Query: 60 EELGEIQLVRIEKRKYWLNDDWYLKYITLKTPH-GDYIEFPCYRWI 104
LG++ VR+ W++ ++ + P G + FPC RW+
Sbjct: 125 --LGDLWKVRLGHDNTGKAPGWFVDWVEVDAPSLGKCMTFPCGRWL 168
Score = 46.6 bits (109), Expect = 8e-05
Identities = 30/105 (28%), Positives = 53/105 (50%), Gaps = 4/105 (3%)
Query: 4 YTVTVATGSQWFAGTDDYIYLSLVGSAGCSEKHLLDKP--FYNDFERGAVDSYDVTVDEE 61
Y+V + TG+ AGTD +Y+++ G G + + L K N FERG D++ + +
Sbjct: 351 YSVQIFTGNIPGAGTDAKVYITIYGDLGDTGERYLGKSENRTNKFERGTADTFIIEA-AD 409
Query: 62 LGEIQLVRIEKRKYWLNDDWYLKYITL-KTPHGDYIEFPCYRWIT 105
LG I +++ DWY++ + + + D F C RW++
Sbjct: 410 LGVIYKIKLRHDNSKWCADWYVEKVEIWNDTNEDEFLFLCGRWLS 454
Score = 43.9 bits (102), Expect = 5e-04
Identities = 32/114 (28%), Positives = 52/114 (45%), Gaps = 5/114 (4%)
Query: 3 SYTVTVATGSQWFAGTDDYIYLSLVGSAGCSEKHLLDKPF-YNDFERGAVDSYDVTVDEE 61
SYTV V T AGTD +++ + G G S L + +N FER D+++
Sbjct: 775 SYTVAVKTSDILGAGTDANVFIIIFGENGDSGTLALKQSANWNKFERNNTDTFNFPDMLS 834
Query: 62 LGEIQLVRIEKRKYWLNDDWYLKYITLK-TPHGDYIEFPCYRWIT---GDVEVV 111
LG + +R+ + W+L Y+ +K + F C W++ GD + V
Sbjct: 835 LGHLCKLRVWHDNKGIFPGWHLSYVDVKDNSRDETFHFQCDCWLSKSEGDGQTV 888
Score = 42.0 bits (97), Expect = 0.002
Identities = 34/114 (29%), Positives = 57/114 (50%), Gaps = 17/114 (14%)
Query: 4 YTVTVATGSQWFAGTDDYIYLSLVG-SAGCSEKHLL------DKPFYNDFERGAVDSYDV 56
Y +T+ T + AGTD I++ + G A C+++ L K F FER + + V
Sbjct: 197 YEITLYTSDVFAAGTDANIFIIIYGCDAVCTQQKYLCTNKREQKQF---FERKSASRFIV 253
Query: 57 TVDEELGEI-QLVRIEKRKYWLNDDWYLKYITLK--TPHGDYIE---FPCYRWI 104
+ E++GEI + +RI +N W+ ++ ++ P D E FPC RW+
Sbjct: 254 EL-EDVGEIIEKIRIGHNNTGMNPGWHCSHVDIRRLLPDKDGAETLTFPCDRWL 306
Score = 38.9 bits (89), Expect = 0.016
Identities = 31/103 (30%), Positives = 50/103 (48%), Gaps = 3/103 (2%)
Query: 4 YTVTVATGSQWFAGTDDYIYLSLVGSAGCSEKHLLDKPFYNDFERGAVDSYDVTVDEELG 63
Y +TV TG GTD I+++L G G +E+ LDK FER D++ + + ++
Sbjct: 649 YEMTVWTGDVVGGGTDSNIFMTLYGINGSTEEMQLDKKKAR-FEREQNDTFIMEI-LDIA 706
Query: 64 EIQLVRIEKRKYWLNDDWYLKYITLKTPH-GDYIEFPCYRWIT 105
+RI +W+L+ I LK + GD F W++
Sbjct: 707 PFTKMRIRIDGLGSRPEWFLERILLKNMNTGDLTMFYYGDWLS 749
Score = 37.7 bits (86), Expect = 0.035
Identities = 19/51 (37%), Positives = 30/51 (58%)
Query: 4 YTVTVATGSQWFAGTDDYIYLSLVGSAGCSEKHLLDKPFYNDFERGAVDSY 54
Y V V TG + AGTD +++++ G+ G + K L + N FERG+ D +
Sbjct: 1045 YEVIVTTGYEPGAGTDANVFVTIFGANGDTGKRELKQKMRNLFERGSTDRF 1095
Score = 30.4 bits (67), Expect = 5.6
Identities = 28/107 (26%), Positives = 45/107 (42%), Gaps = 4/107 (3%)
Query: 4 YTVTVATGSQWFAGTDDYIYLSLVGSAGCSEKHL-LDKP-FYNDFERGAVDSYDVTVDEE 61
Y V+V TG A TD ++ L+G K + LD P F RG+V+ + V +
Sbjct: 518 YYVSVTTGKHKDAATDSRAFIFLIGEDDERSKRIWLDYPRGKRGFSRGSVEEFYV-AGLD 576
Query: 62 LGEIQLVRIEKRKYWLNDDWYLKYITLKTP-HGDYIEFPCYRWITGD 107
+G I+ + + W ++ + L P G C W+ D
Sbjct: 577 VGIIKKIELGHDGASPESCWLVEELCLAVPTQGTKYMLNCNCWLAKD 623
>gi|239756622 PREDICTED: polycystic kidney disease 1-like 3 [Homo
sapiens]
Length = 1732
Score = 46.2 bits (108), Expect = 1e-04
Identities = 26/83 (31%), Positives = 41/83 (49%)
Query: 4 YTVTVATGSQWFAGTDDYIYLSLVGSAGCSEKHLLDKPFYNDFERGAVDSYDVTVDEELG 63
Y + V TG + A T + ++L GS G SE H L P FERG +D + +T LG
Sbjct: 745 YLIQVYTGYRRSAATTAKVVITLYGSEGRSEPHHLCDPQKTVFERGGLDVFLLTTWTSLG 804
Query: 64 EIQLVRIEKRKYWLNDDWYLKYI 86
+ +R+ ++ WY+ +
Sbjct: 805 NLHSLRLWHDNSGVSPSWYVSQV 827
>gi|239751108 PREDICTED: polycystic kidney disease 1-like 3 [Homo
sapiens]
Length = 1731
Score = 46.2 bits (108), Expect = 1e-04
Identities = 26/83 (31%), Positives = 41/83 (49%)
Query: 4 YTVTVATGSQWFAGTDDYIYLSLVGSAGCSEKHLLDKPFYNDFERGAVDSYDVTVDEELG 63
Y + V TG + A T + ++L GS G SE H L P FERG +D + +T LG
Sbjct: 745 YLIQVYTGYRRSAATTAKVVITLYGSEGRSEPHHLCDPQKTVFERGGLDVFLLTTWTSLG 804
Query: 64 EIQLVRIEKRKYWLNDDWYLKYI 86
+ +R+ ++ WY+ +
Sbjct: 805 NLHSLRLWHDNSGVSPSWYVSQV 827
>gi|239745596 PREDICTED: polycystin 1-like 3 [Homo sapiens]
Length = 1731
Score = 46.2 bits (108), Expect = 1e-04
Identities = 26/83 (31%), Positives = 41/83 (49%)
Query: 4 YTVTVATGSQWFAGTDDYIYLSLVGSAGCSEKHLLDKPFYNDFERGAVDSYDVTVDEELG 63
Y + V TG + A T + ++L GS G SE H L P FERG +D + +T LG
Sbjct: 745 YLIQVYTGYRRSAATTAKVVITLYGSEGRSEPHHLCDPQKTVFERGGLDVFLLTTWTSLG 804
Query: 64 EIQLVRIEKRKYWLNDDWYLKYI 86
+ +R+ ++ WY+ +
Sbjct: 805 NLHSLRLWHDNSGVSPSWYVSQV 827
>gi|31559825 polycystin 1-like 3 [Homo sapiens]
Length = 1732
Score = 46.2 bits (108), Expect = 1e-04
Identities = 26/83 (31%), Positives = 41/83 (49%)
Query: 4 YTVTVATGSQWFAGTDDYIYLSLVGSAGCSEKHLLDKPFYNDFERGAVDSYDVTVDEELG 63
Y + V TG + A T + ++L GS G SE H L P FERG +D + +T LG
Sbjct: 745 YLIQVYTGYRRSAATTAKVVITLYGSEGRSEPHHLCDPQKTVFERGGLDVFLLTTWTSLG 804
Query: 64 EIQLVRIEKRKYWLNDDWYLKYI 86
+ +R+ ++ WY+ +
Sbjct: 805 NLHSLRLWHDNSGVSPSWYVSQV 827
>gi|116006951 polycystin 1-like 2 isoform a [Homo sapiens]
Length = 2459
Score = 44.7 bits (104), Expect = 3e-04
Identities = 28/83 (33%), Positives = 42/83 (50%)
Query: 4 YTVTVATGSQWFAGTDDYIYLSLVGSAGCSEKHLLDKPFYNDFERGAVDSYDVTVDEELG 63
Y VTV TG + A T + ++L G G E H L P FERGAVD++ ++ LG
Sbjct: 1392 YLVTVYTGHRRGAATSSKVTVTLYGLDGEREPHHLADPDTPVFERGAVDAFLLSTLFPLG 1451
Query: 64 EIQLVRIEKRKYWLNDDWYLKYI 86
E++ +R+ WY+ +
Sbjct: 1452 ELRSLRLWHDNSGDRPSWYVSRV 1474
>gi|19923084 polycystin-1L1 [Homo sapiens]
Length = 2849
Score = 40.8 bits (94), Expect = 0.004
Identities = 26/103 (25%), Positives = 48/103 (46%), Gaps = 1/103 (0%)
Query: 4 YTVTVATGSQWFAGTDDYIYLSLVGSAGCSEKHLLDKPFYNDFERGAVDSYDVTVDEELG 63
Y V + TG + A +Y+ L G G SE L P FER + ++ ++ +LG
Sbjct: 1798 YAVVIDTGFRAPARLTSKVYIVLCGDNGLSETKELSCPEKPLFERNSRHTFILSAPAQLG 1857
Query: 64 EIQLVRIEKRKYWLNDDWYLKYITLKTPH-GDYIEFPCYRWIT 105
++ +R+ + W++ ++ +K H G FP W++
Sbjct: 1858 LLRKIRLWHDSRGPSPGWFISHVMVKELHTGQGWFFPAQCWLS 1900
>gi|56790932 echinoderm microtubule associated protein like 1
isoform a [Homo sapiens]
Length = 834
Score = 33.1 bits (74), Expect = 0.86
Identities = 24/100 (24%), Positives = 48/100 (48%), Gaps = 14/100 (14%)
Query: 479 WEAIRTFTAEVVDIYYEGDQ---VVEEDPE-----LQDFVNDVYVYGM--RGRKSSGFPK 528
W T T ++V ++ +G++ V+ P+ + N +Y+YG+ GRK + K
Sbjct: 627 WFVFDTETKDLVTVHTDGNEQLSVMRYSPDGNFLAIGSHDNCIYIYGVSDNGRKYTRVGK 686
Query: 529 SVKSREQLSEYLTVVIFTASAQHAAVNFGQYDWCSWIPNA 568
S ++T + ++ ++Q N G Y+ W+P+A
Sbjct: 687 CSGH----SSFITHLDWSVNSQFLVSNSGDYEILYWVPSA 722
>gi|56790930 echinoderm microtubule associated protein like 1
isoform b [Homo sapiens]
Length = 815
Score = 33.1 bits (74), Expect = 0.86
Identities = 24/100 (24%), Positives = 48/100 (48%), Gaps = 14/100 (14%)
Query: 479 WEAIRTFTAEVVDIYYEGDQ---VVEEDPE-----LQDFVNDVYVYGM--RGRKSSGFPK 528
W T T ++V ++ +G++ V+ P+ + N +Y+YG+ GRK + K
Sbjct: 608 WFVFDTETKDLVTVHTDGNEQLSVMRYSPDGNFLAIGSHDNCIYIYGVSDNGRKYTRVGK 667
Query: 529 SVKSREQLSEYLTVVIFTASAQHAAVNFGQYDWCSWIPNA 568
S ++T + ++ ++Q N G Y+ W+P+A
Sbjct: 668 CSGH----SSFITHLDWSVNSQFLVSNSGDYEILYWVPSA 703
>gi|205360962 polycystin 1 isoform 2 precursor [Homo sapiens]
Length = 4302
Score = 32.7 bits (73), Expect = 1.1
Identities = 20/86 (23%), Positives = 39/86 (45%), Gaps = 2/86 (2%)
Query: 4 YTVTVATGSQWFAGTDDYIYLSLVGSAGCSEKHLLDKPFYNDFERGAVDSYDVTVDEELG 63
Y + V TG +GT ++ + L G S LD F R ++D + + LG
Sbjct: 3120 YEILVKTGWGRGSGTTAHVGIMLYGVDSRSGHRHLDGD--RAFHRNSLDIFRIATPHSLG 3177
Query: 64 EIQLVRIEKRKYWLNDDWYLKYITLK 89
+ +R+ L+ W+L+++ ++
Sbjct: 3178 SVWKIRVWHDNKGLSPAWFLQHVIVR 3203
>gi|205360954 polycystin 1 isoform 1 precursor [Homo sapiens]
Length = 4303
Score = 32.7 bits (73), Expect = 1.1
Identities = 20/86 (23%), Positives = 39/86 (45%), Gaps = 2/86 (2%)
Query: 4 YTVTVATGSQWFAGTDDYIYLSLVGSAGCSEKHLLDKPFYNDFERGAVDSYDVTVDEELG 63
Y + V TG +GT ++ + L G S LD F R ++D + + LG
Sbjct: 3120 YEILVKTGWGRGSGTTAHVGIMLYGVDSRSGHRHLDGD--RAFHRNSLDIFRIATPHSLG 3177
Query: 64 EIQLVRIEKRKYWLNDDWYLKYITLK 89
+ +R+ L+ W+L+++ ++
Sbjct: 3178 SVWKIRVWHDNKGLSPAWFLQHVIVR 3203
>gi|38348294 hypothetical protein LOC339145 [Homo sapiens]
Length = 304
Score = 31.6 bits (70), Expect = 2.5
Identities = 35/143 (24%), Positives = 60/143 (41%), Gaps = 14/143 (9%)
Query: 437 VQRAMKDLTYASLCFPEAIKARGMESKEDIPYYFYRDDGLLVWEAIRTFTAEVVDIYYEG 496
VQRA D + +L E + + +D+ +F + E + F A+ V++Y
Sbjct: 149 VQRAAVDSSRTTLQLEETVDGFQRQKLKDLQKFFC---DFVTIEMV--FHAKAVEVYSSA 203
Query: 497 DQVVEE---DPELQDF---VNDVYV-YGMRGRKSSGFPKSVKSREQLSEYLTVVIFTASA 549
Q +E+ + +L DF + VY Y R ++ P SV L V + A+
Sbjct: 204 FQTLEKYDLERDLLDFRAKMQGVYGHYDTRLLANTSPPPSVLQSLASQGTLQVQLSRANE 263
Query: 550 --QHAAVNFGQYDWCSWIPNAPP 570
+H N G++ C W+ P
Sbjct: 264 DPEHPHANHGRFSLCEWVVKGQP 286
>gi|22749183 leucine rich repeat and Ig domain containing 2 [Homo
sapiens]
Length = 606
Score = 31.2 bits (69), Expect = 3.3
Identities = 27/102 (26%), Positives = 45/102 (44%), Gaps = 6/102 (5%)
Query: 247 RRCTELPEKLPVTTEMVECSLERQLSLEQEVQQGNIFIVDFELLDGIDANKTDPCTLQFL 306
RR +PE +P+ T++++ S R S+ E + + +L D I AN +P L
Sbjct: 46 RRLIAIPEGIPIETKILDLSKNRLKSVNPEEFISYPLLEEIDLSDNIIAN-VEPGAFNNL 104
Query: 307 AAPICLLYKNLANKIVPIAI-----QLNQIPGDENPIFLPSD 343
L K K+VP+ + L ++ EN I + D
Sbjct: 105 FNLRSLRLKGNRLKLVPLGVFTGLSNLTKLDISENKIVILLD 146
>gi|239049540 FCH domain only 1 isoform c [Homo sapiens]
Length = 839
Score = 30.8 bits (68), Expect = 4.3
Identities = 12/25 (48%), Positives = 17/25 (68%), Gaps = 5/25 (20%)
Query: 563 SWIPN-----APPTMRAPPPTAKGV 582
SW+P +PP+ RAPPP A+G+
Sbjct: 441 SWVPRPGTPQSPPSCRAPPPEARGI 465
>gi|239049457 FCH domain only 1 isoform b [Homo sapiens]
Length = 889
Score = 30.8 bits (68), Expect = 4.3
Identities = 12/25 (48%), Positives = 17/25 (68%), Gaps = 5/25 (20%)
Query: 563 SWIPN-----APPTMRAPPPTAKGV 582
SW+P +PP+ RAPPP A+G+
Sbjct: 491 SWVPRPGTPQSPPSCRAPPPEARGI 515
>gi|29789054 FCH domain only 1 isoform b [Homo sapiens]
Length = 889
Score = 30.8 bits (68), Expect = 4.3
Identities = 12/25 (48%), Positives = 17/25 (68%), Gaps = 5/25 (20%)
Query: 563 SWIPN-----APPTMRAPPPTAKGV 582
SW+P +PP+ RAPPP A+G+
Sbjct: 491 SWVPRPGTPQSPPSCRAPPPEARGI 515
Database: hs.faa
Posted date: Aug 4, 2009 4:42 PM
Number of letters in database: 18,247,518
Number of sequences in database: 37,866
Lambda K H
0.322 0.138 0.431
Gapped
Lambda K H
0.267 0.0410 0.140
Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Hits to DB: 26,106,062
Number of Sequences: 37866
Number of extensions: 1160486
Number of successful extensions: 2920
Number of sequences better than 10.0: 30
Number of HSP's better than 10.0 without gapping: 25
Number of HSP's successfully gapped in prelim test: 7
Number of HSP's that attempted gapping in prelim test: 2819
Number of HSP's gapped (non-prelim): 62
length of query: 674
length of database: 18,247,518
effective HSP length: 109
effective length of query: 565
effective length of database: 14,120,124
effective search space: 7977870060
effective search space used: 7977870060
T: 11
A: 40
X1: 16 ( 7.4 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 41 (21.9 bits)
S2: 65 (29.6 bits)
Search results were obtained with NCBI BLAST and RefSeq entries.
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Guide to the Human Genome
Copyright © 2010 by Stewart Scherer. All rights reserved.