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Search of human proteins with 44890065
BLASTP 2.2.11 [Jun-05-2005]
Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer,
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997),
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs", Nucleic Acids Res. 25:3389-3402.
Query= gi|44890065 hypothetical protein LOC6936 [Homo sapiens]
(781 letters)
Database: hs.faa
37,866 sequences; 18,247,518 total letters
Searching..................................................done
Score E
Sequences producing significant alignments: (bits) Value
gi|44890065 hypothetical protein LOC6936 [Homo sapiens] 1542 0.0
gi|22035565 GC-rich sequence DNA-binding factor candidate isofor... 422 e-118
gi|22035569 GC-rich sequence DNA-binding factor candidate isofor... 333 4e-91
gi|63252906 tropomyosin 1 alpha chain isoform 7 [Homo sapiens] 58 4e-08
gi|63252902 tropomyosin 1 alpha chain isoform 2 [Homo sapiens] 52 2e-06
gi|63252900 tropomyosin 1 alpha chain isoform 4 [Homo sapiens] 52 3e-06
gi|16262452 cingulin [Homo sapiens] 50 6e-06
gi|38569484 kinesin family member 21A [Homo sapiens] 49 2e-05
gi|109255234 centrosomal protein 290kDa [Homo sapiens] 48 3e-05
gi|154354990 ankyrin repeat domain 26 [Homo sapiens] 48 3e-05
gi|22538393 A-kinase anchor protein 9 isoform 3 [Homo sapiens] 47 7e-05
gi|22538387 A-kinase anchor protein 9 isoform 2 [Homo sapiens] 46 1e-04
gi|63252896 tropomyosin 1 alpha chain isoform 3 [Homo sapiens] 46 2e-04
gi|20336205 transcriptional regulator ATRX isoform 2 [Homo sapiens] 45 2e-04
gi|20336209 transcriptional regulator ATRX isoform 1 [Homo sapiens] 45 2e-04
gi|21735569 claspin [Homo sapiens] 45 3e-04
gi|217272804 hyaluronan-mediated motility receptor isoform d [Ho... 45 3e-04
gi|217272802 hyaluronan-mediated motility receptor isoform a [Ho... 45 3e-04
gi|217416398 hyaluronan-mediated motility receptor isoform c [Ho... 45 3e-04
gi|217416394 hyaluronan-mediated motility receptor isoform b [Ho... 45 3e-04
gi|115648142 centrosomal protein 164kDa [Homo sapiens] 44 8e-04
gi|87299628 biorientation of chromosomes in cell division 1-like... 43 0.001
gi|4758172 dentin matrix acidic phosphoprotein 1 isoform 1 precu... 43 0.001
gi|38045898 RAB6-interacting protein 2 isoform epsilon [Homo sap... 43 0.001
gi|38045896 RAB6-interacting protein 2 isoform delta [Homo sapiens] 43 0.001
gi|121256621 dentin matrix acidic phosphoprotein 1 isoform 2 pre... 43 0.001
gi|209862789 microtubule associated monoxygenase, calponin and L... 42 0.002
gi|22758136 MAP7 domain containing 2 [Homo sapiens] 42 0.002
gi|55770834 centromere protein F [Homo sapiens] 42 0.003
gi|148596984 golgi autoantigen, golgin subfamily b, macrogolgin ... 42 0.003
>gi|44890065 hypothetical protein LOC6936 [Homo sapiens]
Length = 781
Score = 1542 bits (3993), Expect = 0.0
Identities = 781/781 (100%), Positives = 781/781 (100%)
Query: 1 MAHRPKRTFRQRAADSSDSDGAEESPAEPGAPRELPVPGSAEEEPPSGGGRAQVAGLPHR 60
MAHRPKRTFRQRAADSSDSDGAEESPAEPGAPRELPVPGSAEEEPPSGGGRAQVAGLPHR
Sbjct: 1 MAHRPKRTFRQRAADSSDSDGAEESPAEPGAPRELPVPGSAEEEPPSGGGRAQVAGLPHR 60
Query: 61 VRGPRGRGRVWASSRRATKAAPRADEGSESRTLDVSTDEEDKIHHSSESKDDQGLSSDSS 120
VRGPRGRGRVWASSRRATKAAPRADEGSESRTLDVSTDEEDKIHHSSESKDDQGLSSDSS
Sbjct: 61 VRGPRGRGRVWASSRRATKAAPRADEGSESRTLDVSTDEEDKIHHSSESKDDQGLSSDSS 120
Query: 121 SSLGEKELSSTVKIPDAAFIQAARRKRELARAQDDYISLDVQHTSSISGMKRESEDDPES 180
SSLGEKELSSTVKIPDAAFIQAARRKRELARAQDDYISLDVQHTSSISGMKRESEDDPES
Sbjct: 121 SSLGEKELSSTVKIPDAAFIQAARRKRELARAQDDYISLDVQHTSSISGMKRESEDDPES 180
Query: 181 EPDDHEKRIPFTLRPQTLRQRMAEESISRNEETSEESQEDEKQDTWEQQQMRKAVKIIEE 240
EPDDHEKRIPFTLRPQTLRQRMAEESISRNEETSEESQEDEKQDTWEQQQMRKAVKIIEE
Sbjct: 181 EPDDHEKRIPFTLRPQTLRQRMAEESISRNEETSEESQEDEKQDTWEQQQMRKAVKIIEE 240
Query: 241 RDIDLSCGNGSSKVKKFDTSISFPPVNLEIIKKQLNTRLTLLQETHRSHLREYEKYVQDV 300
RDIDLSCGNGSSKVKKFDTSISFPPVNLEIIKKQLNTRLTLLQETHRSHLREYEKYVQDV
Sbjct: 241 RDIDLSCGNGSSKVKKFDTSISFPPVNLEIIKKQLNTRLTLLQETHRSHLREYEKYVQDV 300
Query: 301 KSSKSTIQNLESSSNQALNCKFYKSMKIYVENLIDCLNEKIINIQEIESSMHALLLKQAM 360
KSSKSTIQNLESSSNQALNCKFYKSMKIYVENLIDCLNEKIINIQEIESSMHALLLKQAM
Sbjct: 301 KSSKSTIQNLESSSNQALNCKFYKSMKIYVENLIDCLNEKIINIQEIESSMHALLLKQAM 360
Query: 361 TFMKRRQDELKHESTYLQQLSRKDETSTSGNFSVDEKTQWILEEIESRRTKRRQARVLSG 420
TFMKRRQDELKHESTYLQQLSRKDETSTSGNFSVDEKTQWILEEIESRRTKRRQARVLSG
Sbjct: 361 TFMKRRQDELKHESTYLQQLSRKDETSTSGNFSVDEKTQWILEEIESRRTKRRQARVLSG 420
Query: 421 NCNHQEGTSSDDELPSAEMIDFQKSQGDILQKQKKVFEEVQDDFCNIQNILLKFQQWREK 480
NCNHQEGTSSDDELPSAEMIDFQKSQGDILQKQKKVFEEVQDDFCNIQNILLKFQQWREK
Sbjct: 421 NCNHQEGTSSDDELPSAEMIDFQKSQGDILQKQKKVFEEVQDDFCNIQNILLKFQQWREK 480
Query: 481 FPDSYYEAFISLCIPKLLNPLIRVQLIDWNPLKLESTGLKEMPWFKSVEEFMDSSVEDSK 540
FPDSYYEAFISLCIPKLLNPLIRVQLIDWNPLKLESTGLKEMPWFKSVEEFMDSSVEDSK
Sbjct: 481 FPDSYYEAFISLCIPKLLNPLIRVQLIDWNPLKLESTGLKEMPWFKSVEEFMDSSVEDSK 540
Query: 541 KESSSDKKVLSAIINKTIIPRLTDFVEFLWDPLSTSQTTSLITHCRVILEEHSTCENEVS 600
KESSSDKKVLSAIINKTIIPRLTDFVEFLWDPLSTSQTTSLITHCRVILEEHSTCENEVS
Sbjct: 541 KESSSDKKVLSAIINKTIIPRLTDFVEFLWDPLSTSQTTSLITHCRVILEEHSTCENEVS 600
Query: 601 KSRQDLLKSIVSRMKKAVEDDVFIPLYPKSAVENKTSPHSKFQERQFWSGLKLFRNILLW 660
KSRQDLLKSIVSRMKKAVEDDVFIPLYPKSAVENKTSPHSKFQERQFWSGLKLFRNILLW
Sbjct: 601 KSRQDLLKSIVSRMKKAVEDDVFIPLYPKSAVENKTSPHSKFQERQFWSGLKLFRNILLW 660
Query: 661 NGLLTDDTLQELGLGKLLNRYLIIALLNATPGPDVVKKCNQVAACLPEKWFENSAMRTSI 720
NGLLTDDTLQELGLGKLLNRYLIIALLNATPGPDVVKKCNQVAACLPEKWFENSAMRTSI
Sbjct: 661 NGLLTDDTLQELGLGKLLNRYLIIALLNATPGPDVVKKCNQVAACLPEKWFENSAMRTSI 720
Query: 721 PQLENFIQFLLQSAHKLSRSEFRDEVEEIILILVKIKALNQAESFIGEHHLDHLKSLIKE 780
PQLENFIQFLLQSAHKLSRSEFRDEVEEIILILVKIKALNQAESFIGEHHLDHLKSLIKE
Sbjct: 721 PQLENFIQFLLQSAHKLSRSEFRDEVEEIILILVKIKALNQAESFIGEHHLDHLKSLIKE 780
Query: 781 D 781
D
Sbjct: 781 D 781
>gi|22035565 GC-rich sequence DNA-binding factor candidate isoform 1
[Homo sapiens]
Length = 917
Score = 422 bits (1086), Expect = e-118
Identities = 249/741 (33%), Positives = 423/741 (57%), Gaps = 60/741 (8%)
Query: 95 VSTDEEDKIHHSSESKDDQGLSSDS-SSSLGEKELSSTVKIPDAAFIQAARRKRELARAQ 153
+S ED++ SE ++++ + + S++L + +IPDAAFI AAR+KR++AR
Sbjct: 179 ISEHGEDEMDMESEKEEEKPKTGGAFSNALSSLNVLRPGEIPDAAFIHAARKKRQMAREL 238
Query: 154 DDYISLDVQHTSSISGMKRESEDDPESEPDDHEKR-IPFTLRPQTLRQRMAEES--ISRN 210
D+ D + + RE E+D + DD EKR I F+++ ++ RQ++AEE +
Sbjct: 239 GDFTPHD--NEPGKGRLVREDENDASDDEDDDEKRRIVFSVKEKSQRQKIAEEIGIEGSD 296
Query: 211 EETSEESQEDEKQDTWEQQQMRKAVKIIEER-----DIDL-------------------- 245
++ ++DE+ WEQ+Q+RK + I + + ++++
Sbjct: 297 DDALVTGEQDEELSRWEQEQIRKGINIPQVQASQPAEVNMYYQNTYQTMPYGSSYGIPYS 356
Query: 246 --SCGNGSSKVKKFDTSISFP-------PVNLEIIKKQLNTRLTLLQETHRSHLREYEKY 296
+ G+ +K +K D ++ F PV ++++KKQL RL ++E H+++ +++EK+
Sbjct: 357 YTAYGSSDAKSQKTDNTVPFKTPSNEMTPVTIDLVKKQLKDRLDSMKELHKTNRQQHEKH 416
Query: 297 VQDVKSSKSTIQNLESSSNQ-ALNCKFYKSMKIYVENLIDCLNEKIINIQEIESSMHALL 355
+Q S I+ LE SS KF + M+ YV++L++C +EK+ I E+ES++H L
Sbjct: 417 LQSRVDSTRAIERLEGSSGGIGERYKFLQEMRGYVQDLLECFSEKVPLINELESAIHQLY 476
Query: 356 LKQAMTFMKRRQDELKHESTYLQQLSRKDETSTS-GNFSVD-----EKTQWILEEIESRR 409
++A ++RRQD++K ES+ S K + + +F D E + + E E+RR
Sbjct: 477 KQRASRLVQRRQDDIKDESSEFSSHSNKALMAPNLDSFGRDRALYQEHAKRRIAEREARR 536
Query: 410 TKRRQARVLSGN-CNHQEGTSSDDELPSAEMIDFQKSQGDILQKQKKVFEEVQDDFCNIQ 468
T+RRQAR +G +H EG SSDDE S ++ +F + I ++ KVFE+V + F +I
Sbjct: 537 TRRRQAREQTGKMADHLEGLSSDDEETSTDITNFNLEKDRISKESGKVFEDVLESFYSID 596
Query: 469 NILLKFQQWREKFPDSYYEAFISLCIPKLLNPLIRVQLIDWNPLKLESTGLKEMPWFKSV 528
I +F+ WR K+ SY +A+I LC+PKL NPLIR+QL+ W PL+ + + M WF+S+
Sbjct: 597 CIKSQFEAWRSKYYTSYKDAYIGLCLPKLFNPLIRLQLLTWTPLEAKCRDFENMLWFESL 656
Query: 529 EEFMDSSVEDSKKESSSDKKVLSAIINKTIIPRLTDFVEFLWDPLSTSQTTSLITHCRVI 588
+ E +++ D +L I+ K I+P+LT E +WDP ST+QT+ ++ +
Sbjct: 657 LFY--GCEEREQEKDDVDVALLPTIVEKVILPKLTVIAENMWDPFSTTQTSRMVGITLKL 714
Query: 589 LEEHSTCENEVSKSRQDLLKSIVSRMKKAVEDDVFIPLYPKSAVENKTSPHSKFQERQFW 648
+ + + N +K+ Q LK+++ RM++ ++DDVF+PLYPK+ +ENK S F +RQFW
Sbjct: 715 INGYPSVVNAENKNTQVYLKALLLRMRRTLDDDVFMPLYPKNVLENKNSGPYLFFQRQFW 774
Query: 649 SGLKLFRNILLWNGLLTDDTLQELGLGKLLNRYLIIALLNATPGPDVVKKCNQVAACLPE 708
S +KL N L W G+ ++ TLQEL + LLNRY+++A N+ G D +KK V C P+
Sbjct: 775 SSVKLLGNFLQWYGIFSNKTLQELSIDGLLNRYILMAFQNSEYGDDSIKKAQNVINCFPK 834
Query: 709 KWFENSAMRTSIPQLENFIQFLLQSAHKLSRSEF----------RDEVEEIILILVKIKA 758
+WF N +I QLENF ++L+ A + R+ R+ +++I+ +L ++A
Sbjct: 835 QWFMNLKGERTISQLENFCRYLVHLADTIYRNSIGCSDVEKRNARENIKQIVKLLASVRA 894
Query: 759 LNQAESFIGEHHLDHLKSLIK 779
L+ A S +H++ KSLI+
Sbjct: 895 LDHAMSVASDHNVKEFKSLIE 915
Score = 33.1 bits (74), Expect = 1.0
Identities = 18/52 (34%), Positives = 26/52 (50%), Gaps = 2/52 (3%)
Query: 1 MAHRPKRTFRQRAADSSDSDGAEESPAEPGAPRELPVPGSAEEEPPSGGGRA 52
M + +R ++ DS + + + EP P LP PG+ EE P GG RA
Sbjct: 1 MFRKARRVNVRKRNDSEEEERERDEEQEP--PPLLPPPGTGEEAGPGGGDRA 50
>gi|22035569 GC-rich sequence DNA-binding factor candidate isoform 2
[Homo sapiens]
Length = 815
Score = 333 bits (854), Expect = 4e-91
Identities = 201/607 (33%), Positives = 346/607 (57%), Gaps = 50/607 (8%)
Query: 95 VSTDEEDKIHHSSESKDDQGLSSDS-SSSLGEKELSSTVKIPDAAFIQAARRKRELARAQ 153
+S ED++ SE ++++ + + S++L + +IPDAAFI AAR+KR++AR
Sbjct: 179 ISEHGEDEMDMESEKEEEKPKTGGAFSNALSSLNVLRPGEIPDAAFIHAARKKRQMAREL 238
Query: 154 DDYISLDVQHTSSISGMKRESEDDPESEPDDHEKR-IPFTLRPQTLRQRMAEES--ISRN 210
D+ D + + RE E+D + DD EKR I F+++ ++ RQ++AEE +
Sbjct: 239 GDFTPHD--NEPGKGRLVREDENDASDDEDDDEKRRIVFSVKEKSQRQKIAEEIGIEGSD 296
Query: 211 EETSEESQEDEKQDTWEQQQMRKAVKIIEER-----DIDL-------------------- 245
++ ++DE+ WEQ+Q+RK + I + + ++++
Sbjct: 297 DDALVTGEQDEELSRWEQEQIRKGINIPQVQASQPAEVNMYYQNTYQTMPYGSSYGIPYS 356
Query: 246 --SCGNGSSKVKKFDTSISFP-------PVNLEIIKKQLNTRLTLLQETHRSHLREYEKY 296
+ G+ +K +K D ++ F PV ++++KKQL RL ++E H+++ +++EK+
Sbjct: 357 YTAYGSSDAKSQKTDNTVPFKTPSNEMTPVTIDLVKKQLKDRLDSMKELHKTNRQQHEKH 416
Query: 297 VQDVKSSKSTIQNLESSSNQ-ALNCKFYKSMKIYVENLIDCLNEKIINIQEIESSMHALL 355
+Q S I+ LE SS KF + M+ YV++L++C +EK+ I E+ES++H L
Sbjct: 417 LQSRVDSTRAIERLEGSSGGIGERYKFLQEMRGYVQDLLECFSEKVPLINELESAIHQLY 476
Query: 356 LKQAMTFMKRRQDELKHESTYLQQLSRKDETSTS-GNFSVD-----EKTQWILEEIESRR 409
++A ++RRQD++K ES+ S K + + +F D E + + E E+RR
Sbjct: 477 KQRASRLVQRRQDDIKDESSEFSSHSNKALMAPNLDSFGRDRALYQEHAKRRIAEREARR 536
Query: 410 TKRRQARVLSGN-CNHQEGTSSDDELPSAEMIDFQKSQGDILQKQKKVFEEVQDDFCNIQ 468
T+RRQAR +G +H EG SSDDE S ++ +F + I ++ KVFE+V + F +I
Sbjct: 537 TRRRQAREQTGKMADHLEGLSSDDEETSTDITNFNLEKDRISKESGKVFEDVLESFYSID 596
Query: 469 NILLKFQQWREKFPDSYYEAFISLCIPKLLNPLIRVQLIDWNPLKLESTGLKEMPWFKSV 528
I +F+ WR K+ SY +A+I LC+PKL NPLIR+QL+ W PL+ + + M WF+S+
Sbjct: 597 CIKSQFEAWRSKYYTSYKDAYIGLCLPKLFNPLIRLQLLTWTPLEAKCRDFENMLWFESL 656
Query: 529 EEFMDSSVEDSKKESSSDKKVLSAIINKTIIPRLTDFVEFLWDPLSTSQTTSLITHCRVI 588
E +++ D +L I+ K I+P+LT E +WDP ST+QT+ ++ +
Sbjct: 657 --LFYGCEEREQEKDDVDVALLPTIVEKVILPKLTVIAENMWDPFSTTQTSRMVGITLKL 714
Query: 589 LEEHSTCENEVSKSRQDLLKSIVSRMKKAVEDDVFIPLYPKSAVENKTSPHSKFQERQFW 648
+ + + N +K+ Q LK+++ RM++ ++DDVF+PLYPK+ +ENK S F +RQFW
Sbjct: 715 INGYPSVVNAENKNTQVYLKALLLRMRRTLDDDVFMPLYPKNVLENKNSGPYLFFQRQFW 774
Query: 649 SGLKLFR 655
S +K+ +
Sbjct: 775 SSVKVIK 781
Score = 33.1 bits (74), Expect = 1.0
Identities = 18/52 (34%), Positives = 26/52 (50%), Gaps = 2/52 (3%)
Query: 1 MAHRPKRTFRQRAADSSDSDGAEESPAEPGAPRELPVPGSAEEEPPSGGGRA 52
M + +R ++ DS + + + EP P LP PG+ EE P GG RA
Sbjct: 1 MFRKARRVNVRKRNDSEEEERERDEEQEP--PPLLPPPGTGEEAGPGGGDRA 50
>gi|63252906 tropomyosin 1 alpha chain isoform 7 [Homo sapiens]
Length = 284
Score = 57.8 bits (138), Expect = 4e-08
Identities = 55/265 (20%), Positives = 126/265 (47%), Gaps = 11/265 (4%)
Query: 98 DEEDKIHHSSESKDDQGLSSDSSSSLGEKELSSTVKIPDAAFIQAARRKRELARAQDDYI 157
D+E+ + + +++ D+ + D S L E+++++ K+ + + R EL +A+D +
Sbjct: 14 DKENALDRAEQAEADKKAAEDRSKQL-EEDIAAKEKLLRVSEDERDRVLEELHKAEDSLL 72
Query: 158 SLD---VQHTSSISGMKRESEDDPESEPDDHEKRIPFTLRPQTLRQRMAEESISRNEETS 214
+ + + + ++ + R + E E D ++R+ L+ ++ A+ES +
Sbjct: 73 AAEEAAAKAEADVASLNRRIQL-VEEELDRAQERLATALQKLEEAEKAADESERGMKVIE 131
Query: 215 EESQEDEKQDTWEQQQMRKAVKIIEERDIDLSCGNGSSKVKKFDTSISFPPVNLEIIK-- 272
+Q+DE++ ++ Q+++A I E D D + K+ ++ + E+ +
Sbjct: 132 SRAQKDEEKMEIQEIQLKEAKHIAE--DADRKYEEVARKLVIIESDLERAEERAELSEGQ 189
Query: 273 -KQLNTRLTLLQETHRSHLREYEKYVQDVKSSKSTIQNLESSSNQA-LNCKFYKSMKIYV 330
+QL +L ++ +T ++ + +KY Q + I+ L +A +F + +
Sbjct: 190 VRQLEEQLRIMDQTLKALMAAEDKYSQKEDRYEEEIKVLSDKLKEAETRAEFAERSVTKL 249
Query: 331 ENLIDCLNEKIINIQEIESSMHALL 355
E ID L EK+ + +E SMH +L
Sbjct: 250 EKSIDDLEEKVAHAKEENLSMHQML 274
>gi|63252902 tropomyosin 1 alpha chain isoform 2 [Homo sapiens]
Length = 284
Score = 52.0 bits (123), Expect = 2e-06
Identities = 55/265 (20%), Positives = 121/265 (45%), Gaps = 11/265 (4%)
Query: 98 DEEDKIHHSSESKDDQGLSSDSSSSLGEKELSSTVKIPDAAFIQAARRKRELARAQDDYI 157
D+E+ + + +++ D+ + D S L E+++++ K+ + + R EL +A+D +
Sbjct: 14 DKENALDRAEQAEADKKAAEDRSKQL-EEDIAAKEKLLRVSEDERDRVLEELHKAEDSLL 72
Query: 158 SLD---VQHTSSISGMKRESEDDPESEPDDHEKRIPFTLRPQTLRQRMAEESISRNEETS 214
+ + + + ++ + R + E E D ++R+ L+ ++ A+ES +
Sbjct: 73 AAEEAAAKAEADVASLNRRIQL-VEEELDRAQERLATALQKLEEAEKAADESERGMKVIE 131
Query: 215 EESQEDEKQDTWEQQQMRKAVKIIEERDIDLSCGNGSSKVKKFDTSISFPPVNLEIIK-- 272
+Q+DE++ ++ Q+++A I E D D + K+ ++ + E+ +
Sbjct: 132 SRAQKDEEKMEIQEIQLKEAKHIAE--DADRKYEEVARKLVIIESDLERAEERAELSEGK 189
Query: 273 -KQLNTRLTLLQETHRSHLREYEKYVQDVKSSKSTIQNLESSSNQA-LNCKFYKSMKIYV 330
+L L + +S + EKY Q + I+ L +A +F + +
Sbjct: 190 CAELEEELKTVTNNLKSLEAQAEKYSQKEDRYEEEIKVLSDKLKEAETRAEFAERSVTKL 249
Query: 331 ENLIDCLNEKIINIQEIESSMHALL 355
E ID L EK+ + +E SMH +L
Sbjct: 250 EKSIDDLEEKVAHAKEENLSMHQML 274
>gi|63252900 tropomyosin 1 alpha chain isoform 4 [Homo sapiens]
Length = 284
Score = 51.6 bits (122), Expect = 3e-06
Identities = 57/270 (21%), Positives = 121/270 (44%), Gaps = 21/270 (7%)
Query: 98 DEEDKIHHSSESKDDQGLSSDSSSSLGEKELSSTVKIPD--------AAFIQAARRKREL 149
D+E+ + + +++ D+ + D S L ++ +S K+ + ++ A+ K EL
Sbjct: 14 DKENALDRAEQAEADKKAAEDRSKQLEDELVSLQKKLKGTEDELDKYSEALKDAQEKLEL 73
Query: 150 ARAQDDYISLDVQHTSSISGMKRESEDDPESEPDDHEKRIPFTLRPQTLRQRMAEESISR 209
A + DV + + R + E E D ++R+ L+ ++ A+ES
Sbjct: 74 AEKKATDAEADV------ASLNRRIQL-VEEELDRAQERLATALQKLEEAEKAADESERG 126
Query: 210 NEETSEESQEDEKQDTWEQQQMRKAVKIIEERDIDLSCGNGSSKVKKFDTSISFPPVNLE 269
+ +Q+DE++ ++ Q+++A I E D D + K+ ++ + E
Sbjct: 127 MKVIESRAQKDEEKMEIQEIQLKEAKHIAE--DADRKYEEVARKLVIIESDLERAEERAE 184
Query: 270 IIK---KQLNTRLTLLQETHRSHLREYEKYVQDVKSSKSTIQNLESSSNQA-LNCKFYKS 325
+ + +QL +L ++ +T ++ + +KY Q + I+ L +A +F +
Sbjct: 185 LSEGQVRQLEEQLRIMDQTLKALMAAEDKYSQKEDRYEEEIKVLSDKLKEAETRAEFAER 244
Query: 326 MKIYVENLIDCLNEKIINIQEIESSMHALL 355
+E ID L EK+ + +E SMH +L
Sbjct: 245 SVTKLEKSIDDLEEKVAHAKEENLSMHQML 274
>gi|16262452 cingulin [Homo sapiens]
Length = 1203
Score = 50.4 bits (119), Expect = 6e-06
Identities = 74/373 (19%), Positives = 152/373 (40%), Gaps = 55/373 (14%)
Query: 76 RATKAAPRADEGSESRTLDVSTDEEDKIHHSSESKDDQGLSSDSSSSLGEKELSSTVKIP 135
R K + E S+ + ED + D + +S EK ++
Sbjct: 853 RLNKELEKIGEDSKQALQQLQAQLEDYKEKARREVADAQRQAKDWASEAEKTSGGLSRLQ 912
Query: 136 DAA-----FIQAARRKRELARAQDDYISLDVQHTSSISGMKRESEDDPESEPDDHEKRIP 190
D +QA++ +R+ AR + ++ +Q G+++E+E+ S+ DD +++
Sbjct: 913 DEIQRLRQALQASQAERDTARLDKELLAQRLQ------GLEQEAENKKRSQ-DDRARQL- 964
Query: 191 FTLRPQTLRQRMAEESISRNEETSEESQEDEKQDTWEQQQMRKAVKIIEERDI--DLSCG 248
+ L ++++ +EE + ++ + Q + ++++ER DL C
Sbjct: 965 -----KGLEEKVSRLETELDEEKNTVELLTDRVNRGRDQVDQLRTELMQERSARQDLECD 1019
Query: 249 NGSSKVKKFDTSISFPPVNLEIIKKQLNTRLTLLQETHR-----SHLREYEKYVQDVKSS 303
++LE K L TRL + + S L + +Q+ +
Sbjct: 1020 K----------------ISLERQNKDLKTRLASSEGFQKPSASLSQLESQNQLLQERLQA 1063
Query: 304 KSTIQNLESSSNQALNCKFYKSMKIYVENLIDCLNEKIINIQEIESSMHALLLKQAMTFM 363
+ + + S+N+ L K K + I +E+ + +N Q+ + S+ L
Sbjct: 1064 EEREKTVLQSTNRKLERK-VKELSIQIED-----ERQHVNDQKDQLSLRVKAL------- 1110
Query: 364 KRRQDELKHESTYLQQLSRKDETSTSGNFSVDEKTQWILEEIESRRTKRRQARVLSGNCN 423
KR+ DE + E L L +K + V+E+ Q ++ +E + + R+ +R + +
Sbjct: 1111 KRQVDEAEEEIERLDGLRKKAQREVEEQHEVNEQLQARIKSLE-KDSWRKASRSAAESAL 1169
Query: 424 HQEGTSSDDELPS 436
EG SSD+E S
Sbjct: 1170 KNEGLSSDEEFDS 1182
>gi|38569484 kinesin family member 21A [Homo sapiens]
Length = 1661
Score = 48.9 bits (115), Expect = 2e-05
Identities = 67/319 (21%), Positives = 130/319 (40%), Gaps = 43/319 (13%)
Query: 120 SSSLGEKELSS---TVKIPDAAFIQAARRKRELARAQDDYISLDVQHTSSISGMKRESED 176
SS+ LSS T++I D A + KR+ R + S++G + ++
Sbjct: 520 SSTFSPTILSSDKETIEIIDLAKKDLEKLKRKEKRKK-----------KSVAGKEDNTDT 568
Query: 177 DPESEPDDHEKRIPFTLRPQTLRQRMAEESISRNEETSEESQED-----EKQDTWEQQQM 231
D E + EK + + + E S +EE EE +ED E D + +
Sbjct: 569 DQEKK---EEKGVSERENNELEVEESQEVSDHEDEEEEEEEEEDDIDGGESSDESDSESD 625
Query: 232 RKAVKIIEERDIDLSCGNGSSKVKKFDTSISFPPVNLEIIKKQLNTRLTLLQETHRSHLR 291
KA + +I + + + S L+ +KKQ +L +LQ R
Sbjct: 626 EKANYQADLANITCEIAIKQKLIDELENSQK----RLQTLKKQYEEKLMMLQHKIRDTQL 681
Query: 292 EYEKYVQDVKSSKSTIQNLESSSNQALNCKFYKSMKIYVENLIDCLNEKIINIQEIESSM 351
E ++ +Q++ S +ES S + K ++ E + +N+++ +Q +
Sbjct: 682 ERDQVLQNLGS-------VESYSEEKA-----KKVRSEYEKKLQAMNKELQRLQAAQKE- 728
Query: 352 HALLLKQAMTFMKR----RQDELKHESTYLQQLSRKDETSTSGNFSVDEKTQWILEEIES 407
HA LLK + K+ +QD ++ + T ++ + + E + + + I + +
Sbjct: 729 HARLLKNQSQYEKQLKKLQQDVMEMKKTKVRLMKQMKEEQEKARLTESRRNREIAQLKKD 788
Query: 408 RRTKRRQARVLSGNCNHQE 426
+R + Q R+L +QE
Sbjct: 789 QRKRDHQLRLLEAQKRNQE 807
>gi|109255234 centrosomal protein 290kDa [Homo sapiens]
Length = 2479
Score = 48.1 bits (113), Expect = 3e-05
Identities = 61/292 (20%), Positives = 127/292 (43%), Gaps = 26/292 (8%)
Query: 122 SLGEKELSSTVKIPDAAFIQAARRKRELARAQDDYISLDVQHTSSISGMKRESEDDPESE 181
S G + + +PD +A + +Q++Y+ +Q + + ED E
Sbjct: 753 SEGSNVVFKGIDLPDGIAPSSA----SIINSQNEYLIHLLQELENKEKKLKNLEDSLE-- 806
Query: 182 PDDHEKRIPFTLRPQTLRQRMAEESISRNEETSEESQE-DEKQDTWEQQQMRKAVKIIEE 240
D+ ++ Q+L + +E +S E ES+ E++ E Q + A+K+ E
Sbjct: 807 --DYNRKFAVIRHQQSL---LYKEYLSEKETWKTESKTIKEEKRKLEDQVQQDAIKVKEY 861
Query: 241 RDIDLSCGNGSSKVKKFDTSISFPPVNLEIIKKQLNTRLTLLQETHRSHLREYEKYVQDV 300
++ + S ++KK S L++ +K L + T L E R +E EK
Sbjct: 862 NNLLNALQMDSDEMKKILAENSRKITVLQVNEKSLIRQYTTLVELERQLRKENEK----- 916
Query: 301 KSSKSTIQNLESSSNQALNC-KFYKSMKIYVENLIDCLNEKIINIQEIESSMHALLLKQA 359
K+ + ++E+ + + C + +K M I+ + + + +++ E+E L KQ
Sbjct: 917 --QKNELLSMEAEVCEKIGCLQRFKEMAIFKIAALQKVVDNSVSLSELE-----LANKQY 969
Query: 360 MTFMKRRQDELKHESTYLQQLSRKDETSTSGNFSVDEKTQWILEEIESRRTK 411
+ +D L+ ++ +Q+ S + N S+ E+ + I +E+E + K
Sbjct: 970 NELTAKYRDILQKDNMLVQRTSNLEHLECE-NISLKEQVESINKELEITKEK 1020
Score = 36.6 bits (83), Expect = 0.092
Identities = 65/305 (21%), Positives = 123/305 (40%), Gaps = 37/305 (12%)
Query: 204 EESISRNEETSEESQEDEKQDTWEQQQMRKA---VKIIEERDIDLSCGNGSSKV-KKFDT 259
++ RNEE +E +E K+ QQ+ KA + +E+ L GS+ V K D
Sbjct: 706 DQLTGRNEELRQELRESRKEAINYSQQLAKANLKIDHLEKETSLLRQSEGSNVVFKGIDL 765
Query: 260 SISFPPVNLEIIKKQLNTRLTLLQETHRSH--LREYEKYVQDVKSSKSTIQNLES----- 312
P + II Q + LLQE L+ E ++D + I++ +S
Sbjct: 766 PDGIAPSSASIINSQNEYLIHLLQELENKEKKLKNLEDSLEDYNRKFAVIRHQQSLLYKE 825
Query: 313 --SSNQALNCKFYKSMKIYVENLIDCLNEKIINIQEIESSMHALLL------------KQ 358
S + + K++K L D + + I ++E + ++AL + +
Sbjct: 826 YLSEKETWKTE-SKTIKEEKRKLEDQVQQDAIKVKEYNNLLNALQMDSDEMKKILAENSR 884
Query: 359 AMTFMKRRQDELKHESTYL----QQLSRKDETSTSGNFSVDEKTQWILEEIESRRTKRRQ 414
+T ++ + L + T L +QL +++E + S++ + + E+I + +
Sbjct: 885 KITVLQVNEKSLIRQYTTLVELERQLRKENEKQKNELLSMEAE---VCEKIGCLQRFKEM 941
Query: 415 ARVLSGNCNHQEGTS---SDDELPSAEMIDFQKSQGDILQKQKKVFEEVQD-DFCNIQNI 470
A S S+ EL + + + DILQK + + + + +NI
Sbjct: 942 AIFKIAALQKVVDNSVSLSELELANKQYNELTAKYRDILQKDNMLVQRTSNLEHLECENI 1001
Query: 471 LLKFQ 475
LK Q
Sbjct: 1002 SLKEQ 1006
Score = 31.6 bits (70), Expect = 3.0
Identities = 60/340 (17%), Positives = 139/340 (40%), Gaps = 33/340 (9%)
Query: 85 DEGSESRTLDVSTDEEDK--IHHSSESKDDQGLSSDSSSSLGEKELSSTVKIPDAAFIQA 142
++ E + V EED +HH E + D L+ ++ + S T + FI+
Sbjct: 1564 EKAREEQREIVKKHEEDLHILHHRLELQADSSLNKFKQTAWDLMKQSPTPVPTNKHFIRL 1623
Query: 143 ARRKRELARAQDDYISLDVQHTSSISGMKRESEDDPESEPDDHEKRIPFTLRPQTLRQRM 202
A ++ +A D SL V+ +K+ S+ D E + + E ++ + Q
Sbjct: 1624 AEMEQTVAEQDDSLSSLLVK-------LKKVSQ-DLERQREITELKVKEFENIKLQLQEN 1675
Query: 203 AEESISRNEETSEESQEDEKQDTWEQQQMRKAVKIIEERDIDLSCGNGSSKVKKFDTSIS 262
E+ + + + E+ + Q E Q ++ ++ +E + + V++ + ++
Sbjct: 1676 HEDEVKKVKAEVEDLKYLLDQSQKESQCLKSELQAQKEANSRAPTTTMRNLVERLKSQLA 1735
Query: 263 FPPVNLEIIKK---QLNTRLTLLQETH--------RSHLREYEKYVQDVKSSKSTIQNLE 311
+ + + +L +T E +HL + + + K+ +++L
Sbjct: 1736 LKEKQQKALSRALLELRAEMTAAAEERIISATSQKEAHLNVQQIVDRHTRELKTQVEDL- 1794
Query: 312 SSSNQALNCKFYKSMKIYVENLIDCLNEKIINIQEIESSMHALLLKQAMTFMKRRQDELK 371
+ N + K+ K +L D LN+ +Q+ + + + +L R ++E+
Sbjct: 1795 -NENLLKLKEALKTSKNRENSLTDNLNDLNNELQKKQKAYNKIL---------REKEEID 1844
Query: 372 HESTYLQQLSRKDETSTSGNFSVDEKTQWILEEIESRRTK 411
E+ L++ ++ + G D K Q ++EE++ + K
Sbjct: 1845 QENDELKRQIKRLTSGLQGKPLTDNK-QSLIEELQRKVKK 1883
>gi|154354990 ankyrin repeat domain 26 [Homo sapiens]
Length = 1710
Score = 48.1 bits (113), Expect = 3e-05
Identities = 105/503 (20%), Positives = 218/503 (43%), Gaps = 44/503 (8%)
Query: 150 ARAQDDYISLDVQHTSSISGMKRESEDDPESEPDDHEKRIPFTLRPQTLRQRMAEESISR 209
A ++ + L+ ++ IS E + E + E+ + Q L + ++S+S
Sbjct: 1180 AESEKQSLLLEERNKELISECNHLKERQYQYENEKAEREVVVRQLQQELADTLKKQSMSE 1239
Query: 210 N--EETSEE--SQEDEKQDTWEQQ-QMRKAVKIIEERDID-LSCGNGSSKVKKFDTSISF 263
E TS + EDE QD ++ Q+R ++ ++R + + C + K++ +
Sbjct: 1240 ASLEVTSRYRINLEDETQDLKKKLGQIRNQLQEAQDRHTEAVRC---AEKMQDHKQKLEK 1296
Query: 264 PPVNLEI-IKKQLNTRLTLLQETHRSHLREYEKYVQDVKSSKSTIQNLESSSNQALNCKF 322
L++ +KKQ++ L + ++L E EK + +K Q+LE + +Q +
Sbjct: 1297 DNAKLKVTVKKQMDKIEELQKNLLNANLSEDEK--EQLKKLMELKQSLECNLDQEMKKNV 1354
Query: 323 YKSMKIY-VENLIDCLNEKIINIQEIESSMHALLLKQAMTFMKRRQDELKHESTYLQQLS 381
+I +NL+ +K+ + E S H L K + M + ++LKH+ + L+
Sbjct: 1355 ELEREITGFKNLLKMTRKKLNEYENGEFSFHGDL-KTSQFEMDIQINKLKHK---IDDLT 1410
Query: 382 RKDETSTSGNFSVDEKTQWILEEIESRRTKRRQARVLSGNCNHQE----GTSSDDELPSA 437
+ ET+ S +D K Q + EE+ S +T +++ L N E S E
Sbjct: 1411 AELETAGSKCLHLDTKNQILQEELLSMKTVQKKCEKLQKNKKKLEQEVINLRSHIERNMV 1470
Query: 438 EMIDFQKSQGDILQKQKKVFEEVQDDFCNIQNILLKFQQWREKFPDSYYEAF---ISLCI 494
E+ ++ + +I ++ ++ E + Q+ E+F ++ + + + L I
Sbjct: 1471 ELGQVKQYKQEIEERARQEIAEKLKEVNLFLQAQAASQENLEQFRENNFASMKSQMELRI 1530
Query: 495 PKLLNPL--IRVQLIDWNPLKLE---STGLKEMPWFKSVEEFMDSSVEDSKKESSSDKKV 549
L + L I+ D+N +LE L+E+ KS+ + + E + + K +
Sbjct: 1531 KDLESELSKIKTSQEDFNKTELEKYKQLYLEELKVRKSLSSKLTKTNE--RLAEVNTKLL 1588
Query: 550 LSAIINKTIIPRLTDFVEFLWDPLSTSQTTSLITHCRVILEE------------HSTCEN 597
+ ++++ LT + P + SL + ++I E +++ EN
Sbjct: 1589 VEKQQSRSLFTTLTT-RPVMEPPCVGNLNNSLDLNRKLIPRENLVISTSNPRASNNSMEN 1647
Query: 598 EVSKSRQDLLKSIVSRMKKAVED 620
+SK +Q+L K+I +K+A +
Sbjct: 1648 YLSKMQQELEKNITRELKEAAAE 1670
Score = 30.8 bits (68), Expect = 5.0
Identities = 34/184 (18%), Positives = 79/184 (42%), Gaps = 35/184 (19%)
Query: 89 ESRTLDVSTDEEDKIHHSSESKDDQGLSSDSSSSLGE----------------------- 125
E R +++E++K+ + +S DD + SS + E
Sbjct: 660 EGRPTKKTSNEKNKVKNQIQSMDDVDDLTQSSETASEDCELPHSSYKNFMLLIEQLGMEC 719
Query: 126 KELSSTVKIPDAAFIQAARRKRELARAQDDYISLDVQHTSS-ISGMKRESEDDPESEPD- 183
K+ S +KI DAA + R EL + + +++ ++ ++ ++RE + E +
Sbjct: 720 KDSVSLLKIQDAAL--SCERLLELKKNHCELLTVKIKKMEDKVNVLQRELSETKEIKSQL 777
Query: 184 DHEK--------RIPFTLRPQTLRQRMAEESISRNEETSEESQEDEKQDTWEQQQMRKAV 235
+H+K + F+L + ++R A+ + E +E +++ +QQ+ ++
Sbjct: 778 EHQKVEWERELCSLRFSLNQEEEKRRNADTLYEKIREQLRRKEEQYRKEVEVKQQLELSL 837
Query: 236 KIIE 239
+ +E
Sbjct: 838 QTLE 841
>gi|22538393 A-kinase anchor protein 9 isoform 3 [Homo sapiens]
Length = 3899
Score = 47.0 bits (110), Expect = 7e-05
Identities = 97/513 (18%), Positives = 197/513 (38%), Gaps = 96/513 (18%)
Query: 196 QTLRQRMAEESISRNEETSEESQED------EKQDTWEQQQMRKAVKIIEERDIDLSCGN 249
+ LR+R+ EES +R + E S+ + + T ++Q+++ II+ + +L C
Sbjct: 1897 EELRERLHEESRAREQLAVELSKAEGVIDGYADEKTLFERQIQEKTDIIDRLEQELLC-- 1954
Query: 250 GSSKVKKFDTSISFPPVNLEIIKKQLN--------TRLTLLQETHRSHLREYEKYVQ--- 298
S+++++ + E++ +Q LLQET + + E Q
Sbjct: 1955 ASNRLQELEAEQQQIQEERELLSRQKEAMKAEAGPVEQQLLQETEKLMKEKLEVQCQAEK 2014
Query: 299 --------------DVKSSKSTIQNLES----------SSNQALNCKFYKSMKIYVENLI 334
DV+ S LE NQAL + K K E I
Sbjct: 2015 VRDDLQKQVKALEIDVEEQVSRFIELEQEKNTELMDLRQQNQALEKQLEKMRKFLDEQAI 2074
Query: 335 DCLNEKIINIQEIESSMHALLLKQAMTFMKRRQDELKHESTYLQQLSRKDETSTSGNFSV 394
D +E+ + QEI+ L+Q + + R Q +H++ ++QL+ +
Sbjct: 2075 DREHERDVFQQEIQK------LEQQLKVVPRFQPISEHQTREVEQLAN----------HL 2118
Query: 395 DEKTQWILEEIESRRTKRRQARVLSGNCNHQEGTSSDDELPSAEMIDFQKSQGDI----- 449
EKT E + S+ +R + + E EL A +++ +K G +
Sbjct: 2119 KEKTDKCSELLLSKEQLQRDIQERNEEIEKLEFRVR--ELEQALLVEDRKHFGAVEAKPE 2176
Query: 450 ------LQKQKKVFEEVQDDFCNIQNILLKFQQWREKFPDSYYEAFISLCIPKLLNPLIR 503
LQ ++ + + + N++ L +F++ E + + + L I K R
Sbjct: 2177 LSLEVQLQAERDAIDRKEKEITNLEEQLEQFREELENKNEEVQQLHMQLEIQK-KESTTR 2235
Query: 504 VQLIDWNPLKLESTGLKEMPWFKSVEEFMDSSVEDSKKESSSDKKVLSAIINKTIIPRLT 563
+Q ++ +E FK E + ++++S S+ D+ VL + I +
Sbjct: 2236 LQELE-----------QENKLFKDDMEKLGLAIKESDAMSTQDQHVLFGKFAQIIQEKEV 2284
Query: 564 DFVEFLWDPLSTSQTTSLITHCRVILEEHSTCENEVSKSRQDLLKSIVSRMKKAVEDDVF 623
+ + Q T L ++ T +N+V + + +L++ + ++++ + D
Sbjct: 2285 EIDQL------NEQVTKLQQQLKI------TTDNKVIEEKNELIRDLETQIECLMSDQEC 2332
Query: 624 IPLYPKSAVENKTSPHSKFQERQFWSGLKLFRN 656
+ + +E K Q+ G K N
Sbjct: 2333 VKRNREEEIEQLNEVIEKLQQELANIGQKTSMN 2365
Score = 37.0 bits (84), Expect = 0.070
Identities = 59/306 (19%), Positives = 125/306 (40%), Gaps = 27/306 (8%)
Query: 143 ARRKRELARAQ---DDYISLDVQHTSSISGMKRESEDDPESEPDDHEKRIPFTLRPQTLR 199
A K ELA+ + + + +H + + E +D + ++ + + L+
Sbjct: 3154 AELKSELAQTKLELETTLKAQHKHLKELEAFRLEVKDKTDEVHLLNDTLASEQKKSRELQ 3213
Query: 200 QRMAEES--ISRNEETSEESQEDEKQDTWEQQQMRKAVKIIEERDIDLSCGNGSSKVKK- 256
+ +E + R+EE +E ED K Q+Q + ++ E+ L K++
Sbjct: 3214 WALEKEKAKLGRSEERDKEELEDLKFSLESQKQRNLQLNLLLEQQKQL-LNESQQKIESQ 3272
Query: 257 ---FDTSISFPPVNLEIIKKQLNTRLTLLQETHRSHLREYEKYVQDVKSSKSTIQNLESS 313
+D +S ++ L + ++E + RE E + Q ++SS T Q+
Sbjct: 3273 RMLYDAQLSEEQGRNLELQVLLESEKVRIREMSSTLDRERELHAQ-LQSSDGTGQSRPPL 3331
Query: 314 SNQALNCKFYKSMKIYVENLIDCLNE----KIINIQ-----EIESSMHALLLKQAMTFMK 364
++ L + K ++ +++ LNE K+ ++Q E + +H L+
Sbjct: 3332 PSEDLLKELQKQLEEKHSRIVELLNETEKYKLDSLQTRQQMEKDRQVHRKTLQTEQEANT 3391
Query: 365 RRQDELKHESTYLQQLSRKDETSTSGNFSVD---EKTQWILEEIE----SRRTKRRQARV 417
Q ++ + ++ L R+ E + +D ++ Q I++E + R KR R+
Sbjct: 3392 EGQKKMHELQSKVEDLQRQLEEKRQQVYKLDLEGQRLQGIMQEFQKQELEREEKRESRRI 3451
Query: 418 LSGNCN 423
L N N
Sbjct: 3452 LYQNLN 3457
Score = 32.0 bits (71), Expect = 2.3
Identities = 58/276 (21%), Positives = 112/276 (40%), Gaps = 29/276 (10%)
Query: 266 VNLEIIKKQLNTRLTLLQETHRSHLREYEKYVQDVKSSKSTIQNLESSSNQALNCKFYKS 325
+ LEI KK+ TRL L++ ++ + EK +K S ++ S Q + F K
Sbjct: 2223 MQLEIQKKESTTRLQELEQENKLFKDDMEKLGLAIKES-------DAMSTQDQHVLFGKF 2275
Query: 326 MKIYVEN--LIDCLNEKIINIQEIESSMHALLLKQAMTFMKRRQDELKHESTYLQQLSRK 383
+I E ID LNE++ +Q+ L + ++ + + ++ T ++ L
Sbjct: 2276 AQIIQEKEVEIDQLNEQVTKLQQ------QLKITTDNKVIEEKNELIRDLETQIECLMSD 2329
Query: 384 DETSTSGNFSVDEKTQWILEEIESRRTKRRQARVLSGNCNHQEGTSSDDELP--SAEMID 441
E E+ ++E+++ Q ++ + +E S +L AE +
Sbjct: 2330 QECVKRNREEEIEQLNEVIEKLQQELANIGQKTSMNAHSLSEEADSLKHQLDVVIAEKLA 2389
Query: 442 FQ---KSQGDILQKQKKVFEEVQDDFCNIQNILLKFQQWREKFP--DSYYEAFISLCIPK 496
+ ++ + + K V +E + L ++ RE S E +++ I
Sbjct: 2390 LEQQVETANEEMTFMKNVLKETNFKMNQLTQELFSLKRERESVEKIQSIPENSVNVAIDH 2449
Query: 497 LL--NPLIRVQLIDWNPLKLESTGLKEMPWFKSVEE 530
L P + V L + + LK L+ +FKS EE
Sbjct: 2450 LSKDKPELEVVLTE-DALK----SLENQTYFKSFEE 2480
>gi|22538387 A-kinase anchor protein 9 isoform 2 [Homo sapiens]
Length = 3907
Score = 46.2 bits (108), Expect = 1e-04
Identities = 98/513 (19%), Positives = 201/513 (39%), Gaps = 88/513 (17%)
Query: 196 QTLRQRMAEESISRNEETSEESQED------EKQDTWEQQQMRKAVKIIEERDIDLSCGN 249
+ LR+R+ EES +R + E S+ + + T ++Q+++ II+ + +L C
Sbjct: 1897 EELRERLHEESRAREQLAVELSKAEGVIDGYADEKTLFERQIQEKTDIIDRLEQELLC-- 1954
Query: 250 GSSKVKKFDTSISFPPVNLEIIKKQLN--------TRLTLLQETHRSHLREYEKYVQ--- 298
S+++++ + E++ +Q LLQET + + E Q
Sbjct: 1955 ASNRLQELEAEQQQIQEERELLSRQKEAMKAEAGPVEQQLLQETEKLMKEKLEVQCQAEK 2014
Query: 299 --------------DVKSSKSTIQNLES----------SSNQALNCKFYKSMKIYVENLI 334
DV+ S LE NQAL + K K E I
Sbjct: 2015 VRDDLQKQVKALEIDVEEQVSRFIELEQEKNTELMDLRQQNQALEKQLEKMRKFLDEQAI 2074
Query: 335 DCLNEKIINIQEIESSMHALLLKQAMTFMKRRQDELKHESTYLQQLSR--KDETSTSGNF 392
D +E+ + QEI+ L+Q + + R Q +H++ ++QL+ K++T
Sbjct: 2075 DREHERDVFQQEIQK------LEQQLKVVPRFQPISEHQTREVEQLANHLKEKTDKCSEL 2128
Query: 393 ---------SVDEKTQWILEEIESRRTKRRQARVLSGNCNHQEGTSSDDELPSAEMIDFQ 443
+ E+ + I E++E R + QA ++S + + D + A +
Sbjct: 2129 LLSKEQLQRDIQERNEEI-EKLEFRVRELEQALLVSADTFQK---VEDRKHFGAVEAKPE 2184
Query: 444 KSQGDILQKQKKVFEEVQDDFCNIQNILLKFQQWREKFPDSYYEAFISLCIPKLLNPLIR 503
S LQ ++ + + + N++ L +F++ E + + + L I K R
Sbjct: 2185 LSLEVQLQAERDAIDRKEKEITNLEEQLEQFREELENKNEEVQQLHMQLEIQK-KESTTR 2243
Query: 504 VQLIDWNPLKLESTGLKEMPWFKSVEEFMDSSVEDSKKESSSDKKVLSAIINKTIIPRLT 563
+Q ++ +E FK E + ++++S S+ D+ VL + I +
Sbjct: 2244 LQELE-----------QENKLFKDDMEKLGLAIKESDAMSTQDQHVLFGKFAQIIQEKEV 2292
Query: 564 DFVEFLWDPLSTSQTTSLITHCRVILEEHSTCENEVSKSRQDLLKSIVSRMKKAVEDDVF 623
+ + Q T L ++ T +N+V + + +L++ + ++++ + D
Sbjct: 2293 EIDQL------NEQVTKLQQQLKI------TTDNKVIEEKNELIRDLETQIECLMSDQEC 2340
Query: 624 IPLYPKSAVENKTSPHSKFQERQFWSGLKLFRN 656
+ + +E K Q+ G K N
Sbjct: 2341 VKRNREEEIEQLNEVIEKLQQELANIGQKTSMN 2373
Score = 38.9 bits (89), Expect = 0.019
Identities = 92/433 (21%), Positives = 168/433 (38%), Gaps = 58/433 (13%)
Query: 79 KAAPRADEGSESRTLDVST------DEEDKIHHSSESKDDQGLSSDSSSSLGEK------ 126
K PR SE +T +V ++ DK SK+ + EK
Sbjct: 2095 KVVPRFQPISEHQTREVEQLANHLKEKTDKCSELLLSKEQLQRDIQERNEEIEKLEFRVR 2154
Query: 127 ELSSTVKIPDAAFIQAARRKRELARAQDDYISLDVQHTSSISGMKRESEDDPESEPDDHE 186
EL + + F + RK A +SL+VQ + + R+ ++ E +
Sbjct: 2155 ELEQALLVSADTFQKVEDRKHFGAVEAKPELSLEVQLQAERDAIDRKEKEITNLEEQLEQ 2214
Query: 187 KRIPFTLRPQTLRQRMAEESISRNEETSEESQEDEKQDTWEQQQMRKAVKIIEERDIDLS 246
R + + ++Q + I + E T+ QE E+++ + M K I+E D +S
Sbjct: 2215 FREELENKNEEVQQLHMQLEIQKKESTT-RLQELEQENKLFKDDMEKLGLAIKESDA-MS 2272
Query: 247 CGNGSSKVKKFDTSISFPPVNLEIIKKQLNTRLTLLQ------------ETHRSHLREYE 294
+ KF I V ++ QLN ++T LQ E +R+ E
Sbjct: 2273 TQDQHVLFGKFAQIIQEKEVEID----QLNEQVTKLQQQLKITTDNKVIEEKNELIRDLE 2328
Query: 295 KYVQDVKSSKSTIQNLESSSNQALNCKFYKSMKIYVENLIDCLNEKIINIQEIESSMHAL 354
++ + S + ++ + LN +I+ L +++ NI + ++SM+A
Sbjct: 2329 TQIECLMSDQECVKRNREEEIEQLN------------EVIEKLQQELANIGQ-KTSMNAH 2375
Query: 355 LLKQAMTFMKRRQDELKHESTYL-QQLSRKDETST-------SGNFSVDEKTQWILEEIE 406
L + +K + D + E L QQ+ +E T NF +++ TQ +
Sbjct: 2376 SLSEEADSLKHQLDVVIAEKLALEQQVETANEEMTFMKNVLKETNFKMNQLTQELFSLKR 2435
Query: 407 SRRTKRRQARVLSGNCNHQEGTSSDDELPSAEMI---DFQKSQGDILQKQKKVFEE-VQD 462
R + + + + N S D+ P E++ D KS + Q K FEE +
Sbjct: 2436 ERESVEKIQSIPENSVNVAIDHLSKDK-PELEVVLTEDALKSLEN--QTYFKSFEENGKG 2492
Query: 463 DFCNIQNILLKFQ 475
N++ LL+ +
Sbjct: 2493 SIINLETRLLQLE 2505
Score = 37.0 bits (84), Expect = 0.070
Identities = 59/306 (19%), Positives = 125/306 (40%), Gaps = 27/306 (8%)
Query: 143 ARRKRELARAQ---DDYISLDVQHTSSISGMKRESEDDPESEPDDHEKRIPFTLRPQTLR 199
A K ELA+ + + + +H + + E +D + ++ + + L+
Sbjct: 3162 AELKSELAQTKLELETTLKAQHKHLKELEAFRLEVKDKTDEVHLLNDTLASEQKKSRELQ 3221
Query: 200 QRMAEES--ISRNEETSEESQEDEKQDTWEQQQMRKAVKIIEERDIDLSCGNGSSKVKK- 256
+ +E + R+EE +E ED K Q+Q + ++ E+ L K++
Sbjct: 3222 WALEKEKAKLGRSEERDKEELEDLKFSLESQKQRNLQLNLLLEQQKQL-LNESQQKIESQ 3280
Query: 257 ---FDTSISFPPVNLEIIKKQLNTRLTLLQETHRSHLREYEKYVQDVKSSKSTIQNLESS 313
+D +S ++ L + ++E + RE E + Q ++SS T Q+
Sbjct: 3281 RMLYDAQLSEEQGRNLELQVLLESEKVRIREMSSTLDRERELHAQ-LQSSDGTGQSRPPL 3339
Query: 314 SNQALNCKFYKSMKIYVENLIDCLNE----KIINIQ-----EIESSMHALLLKQAMTFMK 364
++ L + K ++ +++ LNE K+ ++Q E + +H L+
Sbjct: 3340 PSEDLLKELQKQLEEKHSRIVELLNETEKYKLDSLQTRQQMEKDRQVHRKTLQTEQEANT 3399
Query: 365 RRQDELKHESTYLQQLSRKDETSTSGNFSVD---EKTQWILEEIE----SRRTKRRQARV 417
Q ++ + ++ L R+ E + +D ++ Q I++E + R KR R+
Sbjct: 3400 EGQKKMHELQSKVEDLQRQLEEKRQQVYKLDLEGQRLQGIMQEFQKQELEREEKRESRRI 3459
Query: 418 LSGNCN 423
L N N
Sbjct: 3460 LYQNLN 3465
Score = 32.0 bits (71), Expect = 2.3
Identities = 58/276 (21%), Positives = 112/276 (40%), Gaps = 29/276 (10%)
Query: 266 VNLEIIKKQLNTRLTLLQETHRSHLREYEKYVQDVKSSKSTIQNLESSSNQALNCKFYKS 325
+ LEI KK+ TRL L++ ++ + EK +K S ++ S Q + F K
Sbjct: 2231 MQLEIQKKESTTRLQELEQENKLFKDDMEKLGLAIKES-------DAMSTQDQHVLFGKF 2283
Query: 326 MKIYVEN--LIDCLNEKIINIQEIESSMHALLLKQAMTFMKRRQDELKHESTYLQQLSRK 383
+I E ID LNE++ +Q+ L + ++ + + ++ T ++ L
Sbjct: 2284 AQIIQEKEVEIDQLNEQVTKLQQ------QLKITTDNKVIEEKNELIRDLETQIECLMSD 2337
Query: 384 DETSTSGNFSVDEKTQWILEEIESRRTKRRQARVLSGNCNHQEGTSSDDELP--SAEMID 441
E E+ ++E+++ Q ++ + +E S +L AE +
Sbjct: 2338 QECVKRNREEEIEQLNEVIEKLQQELANIGQKTSMNAHSLSEEADSLKHQLDVVIAEKLA 2397
Query: 442 FQ---KSQGDILQKQKKVFEEVQDDFCNIQNILLKFQQWREKFP--DSYYEAFISLCIPK 496
+ ++ + + K V +E + L ++ RE S E +++ I
Sbjct: 2398 LEQQVETANEEMTFMKNVLKETNFKMNQLTQELFSLKRERESVEKIQSIPENSVNVAIDH 2457
Query: 497 LL--NPLIRVQLIDWNPLKLESTGLKEMPWFKSVEE 530
L P + V L + + LK L+ +FKS EE
Sbjct: 2458 LSKDKPELEVVLTE-DALK----SLENQTYFKSFEE 2488
>gi|63252896 tropomyosin 1 alpha chain isoform 3 [Homo sapiens]
Length = 284
Score = 45.8 bits (107), Expect = 2e-04
Identities = 57/270 (21%), Positives = 116/270 (42%), Gaps = 21/270 (7%)
Query: 98 DEEDKIHHSSESKDDQGLSSDSSSSLGEKELSSTVKIPD--------AAFIQAARRKREL 149
D+E+ + + +++ D+ + D S L ++ +S K+ + ++ A+ K EL
Sbjct: 14 DKENALDRAEQAEADKKAAEDRSKQLEDELVSLQKKLKGTEDELDKYSEALKDAQEKLEL 73
Query: 150 ARAQDDYISLDVQHTSSISGMKRESEDDPESEPDDHEKRIPFTLRPQTLRQRMAEESISR 209
A + DV + + R + E E D ++R+ L+ ++ A+ES
Sbjct: 74 AEKKATDAEADV------ASLNRRIQL-VEEELDRAQERLATALQKLEEAEKAADESERG 126
Query: 210 NEETSEESQEDEKQDTWEQQQMRKAVKIIEERDIDLSCGNGSSKVKKFDTSISFPPVNLE 269
+ +Q+DE++ ++ Q+++A I E D D + K+ ++ + E
Sbjct: 127 MKVIESRAQKDEEKMEIQEIQLKEAKHIAE--DADRKYEEVARKLVIIESDLERAEERAE 184
Query: 270 IIK---KQLNTRLTLLQETHRSHLREYEKYVQDVKSSKSTIQNLESSSNQA-LNCKFYKS 325
+ + +L L + +S + EKY Q + I+ L +A +F +
Sbjct: 185 LSEGKCAELEEELKTVTNNLKSLEAQAEKYSQKEDRYEEEIKVLSDKLKEAETRAEFAER 244
Query: 326 MKIYVENLIDCLNEKIINIQEIESSMHALL 355
+E ID L EK+ + +E SMH +L
Sbjct: 245 SVTKLEKSIDDLEEKVAHAKEENLSMHQML 274
>gi|20336205 transcriptional regulator ATRX isoform 2 [Homo sapiens]
Length = 2454
Score = 45.4 bits (106), Expect = 2e-04
Identities = 65/297 (21%), Positives = 118/297 (39%), Gaps = 53/297 (17%)
Query: 16 SSDSDGAEESPAEPGAPRELPVPGSAEEEPPSGGGRAQVAGLP----HRVRGPRGRGRVW 71
SSD DG+ + E G R EE P + QV + PR R R+
Sbjct: 1247 SSDEDGSSDDEPEEGKKR---TGKQNEENPGDEEAKNQVNSESDSDSEESKKPRYRHRLL 1303
Query: 72 ASSRRATKAAPRADEGSESRTLDVSTDEEDKIHHSSESKDDQGLSSDSSSSLGEKELSST 131
R + G E +T + K H + ++ + +SS+ S
Sbjct: 1304 ----RHKLTVSDGESGEEKKT-------KPKEHKEVKGRNRRKVSSEDSE---------- 1342
Query: 132 VKIPDAAFIQAARRKRELARAQDDYISLDVQHTSSISGMKRESEDDPESEPDDHEKRIPF 191
D+ F Q + E++ ++D+ Q + S K E E++ S ++R
Sbjct: 1343 ----DSDF-QESGVSEEVSESEDE------QRPRTRSAKKAELEENQRSYKQKKKRR--- 1388
Query: 192 TLRPQTLRQRMAEESISRNEETSEESQEDEKQDTWEQQQMRKAVKIIEERDIDLSCGNGS 251
R ++ E+S S N+ SEE +E+++++ E+++ + + +E D S G G
Sbjct: 1389 -------RIKVQEDSSSENKSNSEEEEEEKEEEEEEEEEEEEEEE--DENDDSKSPGKGR 1439
Query: 252 SKVKKFDTSISFPPVNLEIIKKQLNTRLTLLQ-ETHRSHLREYEKYVQDVKSSKSTI 307
K++K +K++ R + + E R LRE + ++D +K I
Sbjct: 1440 KKIRKILKDDKLRTETQNALKEEEERRKRIAEREREREKLREVIE-IEDASPTKCPI 1495
Score = 35.0 bits (79), Expect = 0.27
Identities = 43/178 (24%), Positives = 75/178 (42%), Gaps = 18/178 (10%)
Query: 86 EGSESRTLDVSTDEEDKIHHSSESKDDQGLSSDSSSSLGEKELSSTVKIPDAAFIQAARR 145
E + D ++ ++D++ +E +G S DSS K + A+ + +R
Sbjct: 1005 EKKSKKIRDKTSKKKDELSDYAEKSTGKGDSCDSSEDKKSK---------NGAYGREKKR 1055
Query: 146 KRELARAQDDYISLDVQHTSSISGMKRESEDDPESEPDDHEKRIPFTLRPQTLRQRMAEE 205
+ L ++ S Q SS K ++D + D KRI R +R +E
Sbjct: 1056 CKLLGKS-----SRKRQDCSSSDTEKYSMKEDGCNSSDKRLKRIELRERRNLSSKRNTKE 1110
Query: 206 SISRNEET-SEESQEDEKQDTWEQQQMRKAVKIIEERDIDLSCGNGSSKVKKFDTSIS 262
S + + +EES ED K+ +KAV + E++ L S+K K+ D + S
Sbjct: 1111 IQSGSSSSDAEESSEDNKKKKQRTSSKKKAVIVKEKKRNSL---RTSTKRKQADITSS 1165
Score = 30.0 bits (66), Expect = 8.6
Identities = 43/204 (21%), Positives = 88/204 (43%), Gaps = 27/204 (13%)
Query: 81 APRADEGSESRTLDVSTDEEDKIHHSSESKDDQGL---------SSDSSSSLGEKELSST 131
A R + T D + E++K HS + D+QG SSD + E+E S+
Sbjct: 795 AARTTKKRIPNTKDFDSSEDEK--HSKKGMDNQGHKNLKTSQEGSSDDAERKQERETFSS 852
Query: 132 VK---IPDAAFIQAARR--KRELARAQDDYISLDVQHTSSISGMKRESEDDPESEPDDHE 186
+ D ++ R K++ A A D + S + + E E++
Sbjct: 853 AEGTVDKDTTIMELRDRLPKKQQASASTDGVDKLSGKEQSFTSL--EVRKVAETKEKSKH 910
Query: 187 KRIPFTLRPQTLRQRMAEESISRNE--ETSEESQEDEKQDTWEQQQ----MRKAVKIIEE 240
+ + Q +AE+ + +++ ETSE+ ++ K+ T E+++ +K +K+ ++
Sbjct: 911 LKTKTCKKVQDGLSDIAEKFLKKDQSDETSEDDKKQSKKGTEEKKKPSDFKKKVIKMEQQ 970
Query: 241 RDIDLSCGNGSSKVKKFDTSISFP 264
+ S +G+ K+ + + FP
Sbjct: 971 YE---SSSDGTEKLPEREEICHFP 991
>gi|20336209 transcriptional regulator ATRX isoform 1 [Homo sapiens]
Length = 2492
Score = 45.4 bits (106), Expect = 2e-04
Identities = 65/297 (21%), Positives = 118/297 (39%), Gaps = 53/297 (17%)
Query: 16 SSDSDGAEESPAEPGAPRELPVPGSAEEEPPSGGGRAQVAGLP----HRVRGPRGRGRVW 71
SSD DG+ + E G R EE P + QV + PR R R+
Sbjct: 1285 SSDEDGSSDDEPEEGKKR---TGKQNEENPGDEEAKNQVNSESDSDSEESKKPRYRHRLL 1341
Query: 72 ASSRRATKAAPRADEGSESRTLDVSTDEEDKIHHSSESKDDQGLSSDSSSSLGEKELSST 131
R + G E +T + K H + ++ + +SS+ S
Sbjct: 1342 ----RHKLTVSDGESGEEKKT-------KPKEHKEVKGRNRRKVSSEDSE---------- 1380
Query: 132 VKIPDAAFIQAARRKRELARAQDDYISLDVQHTSSISGMKRESEDDPESEPDDHEKRIPF 191
D+ F Q + E++ ++D+ Q + S K E E++ S ++R
Sbjct: 1381 ----DSDF-QESGVSEEVSESEDE------QRPRTRSAKKAELEENQRSYKQKKKRR--- 1426
Query: 192 TLRPQTLRQRMAEESISRNEETSEESQEDEKQDTWEQQQMRKAVKIIEERDIDLSCGNGS 251
R ++ E+S S N+ SEE +E+++++ E+++ + + +E D S G G
Sbjct: 1427 -------RIKVQEDSSSENKSNSEEEEEEKEEEEEEEEEEEEEEE--DENDDSKSPGKGR 1477
Query: 252 SKVKKFDTSISFPPVNLEIIKKQLNTRLTLLQ-ETHRSHLREYEKYVQDVKSSKSTI 307
K++K +K++ R + + E R LRE + ++D +K I
Sbjct: 1478 KKIRKILKDDKLRTETQNALKEEEERRKRIAEREREREKLREVIE-IEDASPTKCPI 1533
Score = 35.0 bits (79), Expect = 0.27
Identities = 43/178 (24%), Positives = 75/178 (42%), Gaps = 18/178 (10%)
Query: 86 EGSESRTLDVSTDEEDKIHHSSESKDDQGLSSDSSSSLGEKELSSTVKIPDAAFIQAARR 145
E + D ++ ++D++ +E +G S DSS K + A+ + +R
Sbjct: 1043 EKKSKKIRDKTSKKKDELSDYAEKSTGKGDSCDSSEDKKSK---------NGAYGREKKR 1093
Query: 146 KRELARAQDDYISLDVQHTSSISGMKRESEDDPESEPDDHEKRIPFTLRPQTLRQRMAEE 205
+ L ++ S Q SS K ++D + D KRI R +R +E
Sbjct: 1094 CKLLGKS-----SRKRQDCSSSDTEKYSMKEDGCNSSDKRLKRIELRERRNLSSKRNTKE 1148
Query: 206 SISRNEET-SEESQEDEKQDTWEQQQMRKAVKIIEERDIDLSCGNGSSKVKKFDTSIS 262
S + + +EES ED K+ +KAV + E++ L S+K K+ D + S
Sbjct: 1149 IQSGSSSSDAEESSEDNKKKKQRTSSKKKAVIVKEKKRNSL---RTSTKRKQADITSS 1203
Score = 30.0 bits (66), Expect = 8.6
Identities = 43/204 (21%), Positives = 88/204 (43%), Gaps = 27/204 (13%)
Query: 81 APRADEGSESRTLDVSTDEEDKIHHSSESKDDQGL---------SSDSSSSLGEKELSST 131
A R + T D + E++K HS + D+QG SSD + E+E S+
Sbjct: 833 AARTTKKRIPNTKDFDSSEDEK--HSKKGMDNQGHKNLKTSQEGSSDDAERKQERETFSS 890
Query: 132 VK---IPDAAFIQAARR--KRELARAQDDYISLDVQHTSSISGMKRESEDDPESEPDDHE 186
+ D ++ R K++ A A D + S + + E E++
Sbjct: 891 AEGTVDKDTTIMELRDRLPKKQQASASTDGVDKLSGKEQSFTSL--EVRKVAETKEKSKH 948
Query: 187 KRIPFTLRPQTLRQRMAEESISRNE--ETSEESQEDEKQDTWEQQQ----MRKAVKIIEE 240
+ + Q +AE+ + +++ ETSE+ ++ K+ T E+++ +K +K+ ++
Sbjct: 949 LKTKTCKKVQDGLSDIAEKFLKKDQSDETSEDDKKQSKKGTEEKKKPSDFKKKVIKMEQQ 1008
Query: 241 RDIDLSCGNGSSKVKKFDTSISFP 264
+ S +G+ K+ + + FP
Sbjct: 1009 YE---SSSDGTEKLPEREEICHFP 1029
>gi|21735569 claspin [Homo sapiens]
Length = 1339
Score = 45.1 bits (105), Expect = 3e-04
Identities = 55/220 (25%), Positives = 91/220 (41%), Gaps = 33/220 (15%)
Query: 69 RVWASSRRATKAAPRADEGSESRTL--DVSTD--EEDKIHHSSESKDDQGLSSDSSSSLG 124
R W + A K PRA + + D+ TD EE K + + L S + G
Sbjct: 534 RFWKHANPAAK--PRAGQTVNVNVIVKDMGTDGKEELKADVVPVTLAPKKLDGASHTKPG 591
Query: 125 EKELSSTVKIPDAAFIQA--ARRKRELARAQDDYISLDVQHTSSISGMKRESEDDPESEP 182
EK K+ +A ++ R+KR+ D+ + + M ESE+D E +
Sbjct: 592 EKLQVLKAKLQEAMKLRRFEERQKRQALFKLDNEDGFEEEEEEE-EEMTDESEEDGEEKV 650
Query: 183 DDHEKRIPFTLRPQTLRQRMAEESISRNEETSEESQEDEKQDTWEQQQMRKAVKIIEERD 242
+ EK EE + EE EE +E+ Q+T E + ++ +E++
Sbjct: 651 EKEEK----------------EEELEEEEEKEEEEEEEGNQETAEFLLSSEEIETKDEKE 694
Query: 243 IDLSCGNGSSKVKKFDTSISFPPVNLEIIKKQLNTRLTLL 282
+D +GSS++ K +S P K L++ TLL
Sbjct: 695 MDKENNDGSSEIGKAVGFLSVP--------KSLSSDSTLL 726
>gi|217272804 hyaluronan-mediated motility receptor isoform d [Homo
sapiens]
Length = 638
Score = 44.7 bits (104), Expect = 3e-04
Identities = 56/250 (22%), Positives = 108/250 (43%), Gaps = 31/250 (12%)
Query: 200 QRMAEESISRNEETSEESQEDEKQDTWEQQQMRKAVKIIEERDIDLSCGNGSSKVKKFDT 259
QR EES + + + EK+ E+ + K ++ IEE +SC S +V+K+
Sbjct: 113 QRSLEESQGKIAQLEGKLVSIEKEKIDEKSETEKLLEYIEE----ISC--ASDQVEKYKL 166
Query: 260 SISFPPVNLEIIKKQLNTRLTLLQETHRSHLREYEKYVQD-------VKSSKSTIQNLES 312
I+ LE K+ N + L+++ ++ K V+D ++ K N
Sbjct: 167 DIA----QLEENLKEKNDEILSLKQSLEENIVILSKQVEDLNVKCQLLEKEKEDHVNRNR 222
Query: 313 SSNQALNCKF--YKSMKIYVENLIDCLNEKIINI-------QEIESSMHALLLKQAMTFM 363
N+ LN + K I + + L +K + I +E+ SS+H L +
Sbjct: 223 EHNENLNAEMQNLKQKFILEQQEREKLQQKELQIDSLLQQEKELSSSLHQKLCSFQEEMV 282
Query: 364 KRR---QDELKHESTYLQQLSRKDETSTSGNFSVDEKTQWILEEIE--SRRTKRRQARVL 418
K + ++ELK L +L +K+E + ++E+ + EE++ + K ++A +
Sbjct: 283 KEKNLFEEELKQTLDELDKLQQKEEQAERLVKQLEEEAKSRAEELKLLEEKLKGKEAELE 342
Query: 419 SGNCNHQEGT 428
+ H + T
Sbjct: 343 KSSAAHTQAT 352
>gi|217272802 hyaluronan-mediated motility receptor isoform a [Homo
sapiens]
Length = 725
Score = 44.7 bits (104), Expect = 3e-04
Identities = 56/250 (22%), Positives = 108/250 (43%), Gaps = 31/250 (12%)
Query: 200 QRMAEESISRNEETSEESQEDEKQDTWEQQQMRKAVKIIEERDIDLSCGNGSSKVKKFDT 259
QR EES + + + EK+ E+ + K ++ IEE +SC S +V+K+
Sbjct: 200 QRSLEESQGKIAQLEGKLVSIEKEKIDEKSETEKLLEYIEE----ISC--ASDQVEKYKL 253
Query: 260 SISFPPVNLEIIKKQLNTRLTLLQETHRSHLREYEKYVQD-------VKSSKSTIQNLES 312
I+ LE K+ N + L+++ ++ K V+D ++ K N
Sbjct: 254 DIA----QLEENLKEKNDEILSLKQSLEENIVILSKQVEDLNVKCQLLEKEKEDHVNRNR 309
Query: 313 SSNQALNCKF--YKSMKIYVENLIDCLNEKIINI-------QEIESSMHALLLKQAMTFM 363
N+ LN + K I + + L +K + I +E+ SS+H L +
Sbjct: 310 EHNENLNAEMQNLKQKFILEQQEREKLQQKELQIDSLLQQEKELSSSLHQKLCSFQEEMV 369
Query: 364 KRR---QDELKHESTYLQQLSRKDETSTSGNFSVDEKTQWILEEIE--SRRTKRRQARVL 418
K + ++ELK L +L +K+E + ++E+ + EE++ + K ++A +
Sbjct: 370 KEKNLFEEELKQTLDELDKLQQKEEQAERLVKQLEEEAKSRAEELKLLEEKLKGKEAELE 429
Query: 419 SGNCNHQEGT 428
+ H + T
Sbjct: 430 KSSAAHTQAT 439
>gi|217416398 hyaluronan-mediated motility receptor isoform c [Homo
sapiens]
Length = 709
Score = 44.7 bits (104), Expect = 3e-04
Identities = 56/250 (22%), Positives = 108/250 (43%), Gaps = 31/250 (12%)
Query: 200 QRMAEESISRNEETSEESQEDEKQDTWEQQQMRKAVKIIEERDIDLSCGNGSSKVKKFDT 259
QR EES + + + EK+ E+ + K ++ IEE +SC S +V+K+
Sbjct: 184 QRSLEESQGKIAQLEGKLVSIEKEKIDEKSETEKLLEYIEE----ISC--ASDQVEKYKL 237
Query: 260 SISFPPVNLEIIKKQLNTRLTLLQETHRSHLREYEKYVQD-------VKSSKSTIQNLES 312
I+ LE K+ N + L+++ ++ K V+D ++ K N
Sbjct: 238 DIA----QLEENLKEKNDEILSLKQSLEENIVILSKQVEDLNVKCQLLEKEKEDHVNRNR 293
Query: 313 SSNQALNCKF--YKSMKIYVENLIDCLNEKIINI-------QEIESSMHALLLKQAMTFM 363
N+ LN + K I + + L +K + I +E+ SS+H L +
Sbjct: 294 EHNENLNAEMQNLKQKFILEQQEREKLQQKELQIDSLLQQEKELSSSLHQKLCSFQEEMV 353
Query: 364 KRR---QDELKHESTYLQQLSRKDETSTSGNFSVDEKTQWILEEIE--SRRTKRRQARVL 418
K + ++ELK L +L +K+E + ++E+ + EE++ + K ++A +
Sbjct: 354 KEKNLFEEELKQTLDELDKLQQKEEQAERLVKQLEEEAKSRAEELKLLEEKLKGKEAELE 413
Query: 419 SGNCNHQEGT 428
+ H + T
Sbjct: 414 KSSAAHTQAT 423
>gi|217416394 hyaluronan-mediated motility receptor isoform b [Homo
sapiens]
Length = 724
Score = 44.7 bits (104), Expect = 3e-04
Identities = 56/250 (22%), Positives = 108/250 (43%), Gaps = 31/250 (12%)
Query: 200 QRMAEESISRNEETSEESQEDEKQDTWEQQQMRKAVKIIEERDIDLSCGNGSSKVKKFDT 259
QR EES + + + EK+ E+ + K ++ IEE +SC S +V+K+
Sbjct: 199 QRSLEESQGKIAQLEGKLVSIEKEKIDEKSETEKLLEYIEE----ISC--ASDQVEKYKL 252
Query: 260 SISFPPVNLEIIKKQLNTRLTLLQETHRSHLREYEKYVQD-------VKSSKSTIQNLES 312
I+ LE K+ N + L+++ ++ K V+D ++ K N
Sbjct: 253 DIA----QLEENLKEKNDEILSLKQSLEENIVILSKQVEDLNVKCQLLEKEKEDHVNRNR 308
Query: 313 SSNQALNCKF--YKSMKIYVENLIDCLNEKIINI-------QEIESSMHALLLKQAMTFM 363
N+ LN + K I + + L +K + I +E+ SS+H L +
Sbjct: 309 EHNENLNAEMQNLKQKFILEQQEREKLQQKELQIDSLLQQEKELSSSLHQKLCSFQEEMV 368
Query: 364 KRR---QDELKHESTYLQQLSRKDETSTSGNFSVDEKTQWILEEIE--SRRTKRRQARVL 418
K + ++ELK L +L +K+E + ++E+ + EE++ + K ++A +
Sbjct: 369 KEKNLFEEELKQTLDELDKLQQKEEQAERLVKQLEEEAKSRAEELKLLEEKLKGKEAELE 428
Query: 419 SGNCNHQEGT 428
+ H + T
Sbjct: 429 KSSAAHTQAT 438
>gi|115648142 centrosomal protein 164kDa [Homo sapiens]
Length = 1460
Score = 43.5 bits (101), Expect = 8e-04
Identities = 58/312 (18%), Positives = 124/312 (39%), Gaps = 20/312 (6%)
Query: 86 EGSESRTLDVSTDEEDKIHHSSESKDDQGLSSDSSSSLG-------------EKELSSTV 132
EG R LD +E ++ + + + + LG E+EL +
Sbjct: 844 EGEHERRLDKMKEEHQQVMAKAREQYEAEERKQRAELLGHLTGELERLQRAHERELETVR 903
Query: 133 KIPDAAFIQAARRKRELARAQDDYISLDVQHTSSISGMKRESEDDPESEPDDHEKRIPFT 192
+ RR RE R D + LD++ T + R + + + E EK+
Sbjct: 904 QEQHKRLEDLRRRHREQERKLQD-LELDLE-TRAKDVKARLALLEVQEETARREKQQLLD 961
Query: 193 LRPQTLRQRMAEESISRNEETSEESQEDEKQDTWEQQQMRKAVKIIEERDIDLSCGNGSS 252
++ Q + E + + EE+Q++ QQ+R+ + ++ R + L
Sbjct: 962 VQRQVA---LKSEEATATHQQLEEAQKEHTHLLQSNQQLREILDELQARKLKLESQVDLL 1018
Query: 253 KVKKFDTSISFPPVNLEIIKKQLNTRLTLLQETHRSHLREYEKYVQDVKSSKSTIQNLES 312
+ + F + E KKQ R ++E + S E + +++D++ S T Q E
Sbjct: 1019 QAQSQQLQKHFSSLEAEAQKKQHLLREVTVEENNASPHFEPDLHIEDLRKSLGTNQTKEV 1078
Query: 313 SSNQALNCKFYKSMKIYVENLIDCLNEKIINIQEIESSM--HALLLKQAMTFMKRRQDEL 370
SS+ + + + + N+ L+ + + ++ + + +++ T +K Q
Sbjct: 1079 SSSLSQSKEDLYLDSLSSHNVWHLLSAEGVALRSAKEFLVQQTRSMRRRQTALKAAQQHW 1138
Query: 371 KHESTYLQQLSR 382
+HE Q++++
Sbjct: 1139 RHELASAQEVAK 1150
Score = 39.3 bits (90), Expect = 0.014
Identities = 93/463 (20%), Positives = 174/463 (37%), Gaps = 48/463 (10%)
Query: 16 SSDSDGA-EESPAEPGAPRELPVPGSAEEEPPSGGGRAQVAGLPHRVRGPRGRGRVWASS 74
S DSD A +P +P +P SA + G G GLP + + ++ +
Sbjct: 270 SLDSDAAGPPTPCKPSSPGADSSLSSAVGKGRQGSGARP--GLPEKEENEKSEPKI-CRN 326
Query: 75 RRATKAAPRADEGSESRTLDVSTDEEDKIHHSSE--------SKDDQGLSSDSSSSLGEK 126
KA P E +++ + D D S K L SS + E
Sbjct: 327 LVTPKADPTGSEPAKASEKEAPEDTVDAGEEGSRREEAAKEPKKKASALEEGSSDASQEL 386
Query: 127 ELSSTVKIPDAAFIQAARRKRELA-----RAQDDYISLDVQHTSSISG---------MKR 172
E+S +K P + A+ K R++ LDV S + G +
Sbjct: 387 EISEHMKEPQLSDSIASDPKSFHGLDFGFRSRISEHLLDVDVLSPVLGGACRQAQQPLGI 446
Query: 173 ESEDDPESEPDDHEKRIPFTLRPQTLRQRMAEESISRNEETSEESQEDEKQDTWEQQQMR 232
E +DD +S D+ + + L + L + E +++ S ++E+ Q Q + +
Sbjct: 447 EDKDDSQSSQDELQSKQSKGLE-ERLSPPLPHEERAQSPPRSLATEEEPPQGPEGQPEWK 505
Query: 233 KAVKIIEERDIDLSCGNGSSKVKKFDTSISFPPVNLEIIKKQLNTRLTLLQETHRSHLRE 292
+A ++ E+ LS + + PP E K+Q + L
Sbjct: 506 EAEELGEDSAASLSLQLSLQREQA-----PSPPAACEKGKEQ---------HSQAEELGP 551
Query: 293 YEKYVQDVKSSKSTIQNLESSSNQALNCKFYKSMKIYVENLIDCLNEKIINIQEIESSMH 352
++ +D + K + S + + + + E + + E + + E + H
Sbjct: 552 GQEEAEDPEE-KVAVSPTPPVSPEVRSTEPVAPPEQLSEAALKAMEEAVAQVLE-QDQRH 609
Query: 353 ALLLKQAMTFMKRRQDELKHESTYLQQLSRKDETSTSGNFSVDEKTQWILEEIESRRTKR 412
L KQ + R+ + E + +L ++ E S S S+ E+ Q +EE E+R +
Sbjct: 610 LLESKQEK-MQQLREKLCQEEEEEILRLHQQKEQSLS---SLRERLQKAIEEEEARMREE 665
Query: 413 RQARVLSGNCNHQEGTSSD-DELPSAEMIDFQKSQGDILQKQK 454
R+ Q T +D D++ + + QK + ++ +QK
Sbjct: 666 ESQRLSWLRAQVQSSTQADEDQIRAEQEASLQKLREELESQQK 708
>gi|87299628 biorientation of chromosomes in cell division 1-like
[Homo sapiens]
Length = 3051
Score = 43.1 bits (100), Expect = 0.001
Identities = 80/413 (19%), Positives = 164/413 (39%), Gaps = 52/413 (12%)
Query: 73 SSRRATKAAPRADEGSESRTLDVSTDEEDKIHHSSESKDDQGLSSDSSSSLGEKELSSTV 132
+S RA+K P T D STD+E +SE D+ S+ S G + +
Sbjct: 229 TSERASKKLP------SQPTTDTSTDKE----RTSEDMADKEKSTADSGGEGLETAPKSE 278
Query: 133 KIPDAAFIQAARRKRELARAQDDYISLDVQHTSSISGMKRESEDDPESEPDDHEKRIPFT 192
+ D + + ++ I L+ S K +S D E +PD +EK
Sbjct: 279 EFSDLPC--PVEEIKNYTKEHNNLILLNKDVQQESSEQKNKSTDKGEKKPDSNEK----- 331
Query: 193 LRPQTLRQRMAEESISRNEETSEESQEDEKQDTWEQQQMRKAVKIIEERDIDLSCGNGSS 252
E + E+T ++ +K + ++ + K K E + L S+
Sbjct: 332 ----------GERKKEKKEKTEKKFDHSKKSEDTQKVKDEKQAKEKEVESLKLPSEKNSN 381
Query: 253 KVKKFD-TSISFPPVNLEIIKKQLNTRLTLLQETHRSHLREYEKYVQDVKSSKSTIQNLE 311
K K + T F ++ ++ T +T + H S L +E+ ++ + +++ E
Sbjct: 382 KAKTVEGTKEDFSLIDSDV---DGLTDIT-VSSVHTSDLSSFEEDTEEEVVTSDSMEEGE 437
Query: 312 SSSNQALNCKFYKSMKIYVENLIDCLNEKIINIQEIESSMHALLLKQA---MTFMKRRQD 368
+S+ K K+ K + + + + + + +++ + +T +RRQ
Sbjct: 438 ITSDDEEKNKQNKT-KTQTSDSSEGKTKSVRHAYVHKPYLYSKYYSDSDDELTVEQRRQS 496
Query: 369 --ELKHESTYLQQLSRKDETSTSGNFSVDEKTQWILEEIESRRTKRRQARVLSGNCNHQE 426
+ K E +Q++R+ ++EK + E+ +S +TK + + E
Sbjct: 497 IAKEKEERLLRRQINRE---------KLEEKRKQKAEKTKSSKTKGQGRSSVD-----LE 542
Query: 427 GTSSDDELPSAEMIDFQKSQGDILQKQKKVFEEVQDDFCNIQNILLKFQQWRE 479
+S+ P A I + +L+K+ + ++ + D N++ K QQ+ E
Sbjct: 543 ESSTKSLEPKAARIKEVLKERKVLEKKVALSKKRKKDSRNVEENSKKKQQYEE 595
Score = 32.3 bits (72), Expect = 1.7
Identities = 46/215 (21%), Positives = 85/215 (39%), Gaps = 33/215 (15%)
Query: 39 GSAEEEPPSGGGRAQVAGLPHRVRGPRGRGRVW-ASSRRATKAAPRADEG--------SE 89
G E+ ++Q P ++ RGR R + + K + D G S
Sbjct: 2849 GEKPEQNDDDTIKSQEEDQPIIIKRKRGRPRKYPVETTLKMKDDSKTDTGIVTVEQSPSS 2908
Query: 90 SRTLDVSTDEEDKIHHSSESKDDQGLSSDSSSSLGEKELSSTVKIPDAAFIQAARRKREL 149
S+ + TDE +K + + ++ +S+D GE+++ ++V+ + R+ +
Sbjct: 2909 SKLKVMQTDESNK---ETANLQERSISNDD----GEEKIVTSVR-------RRGRKPKRS 2954
Query: 150 ARAQDDYISLDVQHT--SSISGM---KRESEDDPESEPDDHEKRIPFTLRPQTLRQRMAE 204
DD S + + S+S K+E E D E E ++ ++ T R T +
Sbjct: 2955 LTVSDDAESSEPERKRQKSVSDPVEDKKEQESDEEEEEEEEDEPSGATTRSTTRSEAQRS 3014
Query: 205 E-----SISRNEETSEESQEDEKQDTWEQQQMRKA 234
+ SI R E S Q E+ ++KA
Sbjct: 3015 KTQLSPSIKRKREVSPPGARTRGQQRVEEAPVKKA 3049
>gi|4758172 dentin matrix acidic phosphoprotein 1 isoform 1
precursor [Homo sapiens]
Length = 513
Score = 42.7 bits (99), Expect = 0.001
Identities = 77/334 (23%), Positives = 132/334 (39%), Gaps = 44/334 (13%)
Query: 88 SESRTLDVSTDEEDKIHHSSESKDDQGLSSDSSSSLGEKELSSTVKIPDAAFIQAARRKR 147
SE + +D E H DD+G+ SD S+ + +S + ++
Sbjct: 189 SEEHWVGGGSDGESS-HGDGSELDDEGMQSDDPESIRSERGNSRMNSAGMKSKESGENS- 246
Query: 148 ELARAQDDYISLDVQHTS-SISGMKRESEDDPESEPDDHEKRIPFTLRPQTLRQRMAEES 206
E A QD S ++H S I R SE+D SE DD+ + ++ E S
Sbjct: 247 EQANTQDSGGSQLLEHPSRKIFRKSRISEEDDRSELDDNNTM-------EEVKSDSTENS 299
Query: 207 ISRNEETSE-------ESQEDEKQD-TWEQQQMRKAVKIIEERDIDLSCGNGSSKVKKFD 258
SR+ S+ +SQED K++ + E+ Q ++ +LS SS+ ++
Sbjct: 300 NSRDTGLSQPRRDSKGDSQEDSKENLSQEESQNVDGPSSESSQEANLSSQENSSESQEEV 359
Query: 259 TSISF---PPVNLEIIKKQLNTRLTLLQETHRSHLREYEKYVQDVKSSKSTIQNLESSSN 315
S S P ++ Q ++ + E SH + K S+S + +S S+
Sbjct: 360 VSESRGDNPDPTTSYVEDQEDSDSS---EEDSSHTLSHSK-------SESREEQADSESS 409
Query: 316 QALNCKFYKSMKIYVENLIDCLNEKIINIQEIESSMHALLLKQAMTFMKRRQDELKHEST 375
++LN + E + ++ + QE S + Q+ D +S+
Sbjct: 410 ESLN---------FSEESPESPEDENSSSQEGLQSHSSSAESQSEESHSEEDDSDSQDSS 460
Query: 376 YLQQLSRKDETSTSGNFSVDEKTQWILEEIESRR 409
S++D ST S +E Q EIESR+
Sbjct: 461 R----SKEDSNSTESKSSSEEDGQLKNIEIESRK 490
Score = 35.0 bits (79), Expect = 0.27
Identities = 50/238 (21%), Positives = 86/238 (36%), Gaps = 30/238 (12%)
Query: 21 GAEESPAEPGAPRELPVPGSAEEEPPS-----GGGRAQVAGLPHRVRGPR---------- 65
G + + G EL G ++P S G R AG+ + G
Sbjct: 196 GGSDGESSHGDGSELDDEGMQSDDPESIRSERGNSRMNSAGMKSKESGENSEQANTQDSG 255
Query: 66 GRGRVWASSRRATKAAPRADEGSESRTLDVSTDEEDKIHHSSESKD-DQGLSSDSSSSLG 124
G + SR+ + + ++E S D +T EE K + S D GLS S G
Sbjct: 256 GSQLLEHPSRKIFRKSRISEEDDRSELDDNNTMEEVKSDSTENSNSRDTGLSQPRRDSKG 315
Query: 125 E----------KELSSTVKIPDAAFIQAAR--RKRELARAQDDYISLDVQHTSSISGMKR 172
+ +E S V P + Q A + + +Q++ +S +
Sbjct: 316 DSQEDSKENLSQEESQNVDGPSSESSQEANLSSQENSSESQEEVVSESRGDNPDPTTSYV 375
Query: 173 ESEDDPESEPDDHEKRIPFTLRPQTLRQRMAEESISRNEETSEESQEDEKQDTWEQQQ 230
E ++D +S +D + + R+ A+ S + SEES E + + Q+
Sbjct: 376 EDQEDSDSSEEDSSHTLSHSKSES--REEQADSESSESLNFSEESPESPEDENSSSQE 431
>gi|38045898 RAB6-interacting protein 2 isoform epsilon [Homo
sapiens]
Length = 1116
Score = 42.7 bits (99), Expect = 0.001
Identities = 54/254 (21%), Positives = 105/254 (41%), Gaps = 51/254 (20%)
Query: 204 EESISRNEETSEESQEDEKQDTWEQQQ----MRKAVKIIEER----------------DI 243
EE+++ E T E +E +D E+Q+ +K +K ++E+ D+
Sbjct: 619 EEALAEKERTIERLKEQRDRDEREKQEEIDNYKKDLKDLKEKVSLLQGDLSEKEASLLDL 678
Query: 244 DLSCGNGSSKVKKFDTSISFPPVNLEIIKKQLNTRLTLLQETHRSHL------------- 290
+ +S K D+ + + LE K++ + L++ H + L
Sbjct: 679 KEHASSLASSGLKKDSRLKTLEIALEQKKEECLKMESQLKKAHEAALEARASPEMSDRIQ 738
Query: 291 ---REYEKYVQDVKSSKSTIQNLESSSNQALNCKFYKSMKI-YVENLIDCLNEKIINI-- 344
RE +Y + +++ + L + N K K KI +E + N+K+ N+
Sbjct: 739 HLEREITRYKDESSKAQAEVDRLLEILKEVENEKNDKDKKIAELERQVKDQNKKVANLKH 798
Query: 345 -QEIESSMHALLLKQAMTFMKRRQDELKHESTYLQQLSRKD-------ETSTSGNFSVDE 396
+++E A +L++A +RR+D L S LQ RK E + + +
Sbjct: 799 KEQVEKKKSAQMLEEA----RRREDNLNDSSQQLQDSLRKKDDRIEELEEALRESVQITA 854
Query: 397 KTQWILEEIESRRT 410
+ + +L + ES RT
Sbjct: 855 EREMVLAQEESART 868
Score = 37.4 bits (85), Expect = 0.054
Identities = 65/322 (20%), Positives = 143/322 (44%), Gaps = 62/322 (19%)
Query: 88 SESRTLDVSTDE--EDKIHHSSESKDDQGLSSDSSSSLGEKELSSTVKIPDAAFIQAARR 145
S +TL+++ ++ E+ + S+ K + ++ +S E+S ++ + + R
Sbjct: 694 SRLKTLEIALEQKKEECLKMESQLKKAHEAALEARAS---PEMSDRIQHLER---EITRY 747
Query: 146 KRELARAQDDYISLDVQHTSSISGMKRESED---DPESEPDDHEKRIPFTLRPQTLRQR- 201
K E ++AQ + L ++ + K + + + E + D K++ + + ++
Sbjct: 748 KDESSKAQAEVDRL-LEILKEVENEKNDKDKKIAELERQVKDQNKKVANLKHKEQVEKKK 806
Query: 202 ---MAEESISRNEETSEESQE-----DEKQDTWEQ--QQMRKAVKIIEERDIDLSCG--- 248
M EE+ R + ++ SQ+ +K D E+ + +R++V+I ER++ L+
Sbjct: 807 SAQMLEEARRREDNLNDSSQQLQDSLRKKDDRIEELEEALRESVQITAEREMVLAQEESA 866
Query: 249 --NGSSKVKKFDTSISFPPVNLEIIKKQLNTRLTLL--QETHRSHLR-EYEKYVQDVKSS 303
N +V++ ++ LE +K +L++ L +ETH ++LR E K++++V
Sbjct: 867 RTNAEKQVEELLMAMEKVKQELESMKAKLSSTQQSLAEKETHLTNLRAERRKHLEEVLEM 926
Query: 304 KSTIQNLESSSNQALNCKFYKSMKIYVENLIDCLNEKIINIQEIESSMHALLLKQAMTFM 363
K E L+ ++EK NI +E S ++ + +
Sbjct: 927 KQ-------------------------EALLAAISEKDANIALLELSSSKKKTQEEVAAL 961
Query: 364 KRRQDELKHESTYLQQLSRKDE 385
KR +D L +QQL ++ +
Sbjct: 962 KREKDRL------VQQLKQQTQ 977
>gi|38045896 RAB6-interacting protein 2 isoform delta [Homo sapiens]
Length = 1088
Score = 42.7 bits (99), Expect = 0.001
Identities = 54/254 (21%), Positives = 105/254 (41%), Gaps = 51/254 (20%)
Query: 204 EESISRNEETSEESQEDEKQDTWEQQQ----MRKAVKIIEER----------------DI 243
EE+++ E T E +E +D E+Q+ +K +K ++E+ D+
Sbjct: 591 EEALAEKERTIERLKEQRDRDEREKQEEIDNYKKDLKDLKEKVSLLQGDLSEKEASLLDL 650
Query: 244 DLSCGNGSSKVKKFDTSISFPPVNLEIIKKQLNTRLTLLQETHRSHL------------- 290
+ +S K D+ + + LE K++ + L++ H + L
Sbjct: 651 KEHASSLASSGLKKDSRLKTLEIALEQKKEECLKMESQLKKAHEAALEARASPEMSDRIQ 710
Query: 291 ---REYEKYVQDVKSSKSTIQNLESSSNQALNCKFYKSMKI-YVENLIDCLNEKIINI-- 344
RE +Y + +++ + L + N K K KI +E + N+K+ N+
Sbjct: 711 HLEREITRYKDESSKAQAEVDRLLEILKEVENEKNDKDKKIAELERQVKDQNKKVANLKH 770
Query: 345 -QEIESSMHALLLKQAMTFMKRRQDELKHESTYLQQLSRKD-------ETSTSGNFSVDE 396
+++E A +L++A +RR+D L S LQ RK E + + +
Sbjct: 771 KEQVEKKKSAQMLEEA----RRREDNLNDSSQQLQDSLRKKDDRIEELEEALRESVQITA 826
Query: 397 KTQWILEEIESRRT 410
+ + +L + ES RT
Sbjct: 827 EREMVLAQEESART 840
Score = 37.4 bits (85), Expect = 0.054
Identities = 65/322 (20%), Positives = 143/322 (44%), Gaps = 62/322 (19%)
Query: 88 SESRTLDVSTDE--EDKIHHSSESKDDQGLSSDSSSSLGEKELSSTVKIPDAAFIQAARR 145
S +TL+++ ++ E+ + S+ K + ++ +S E+S ++ + + R
Sbjct: 666 SRLKTLEIALEQKKEECLKMESQLKKAHEAALEARAS---PEMSDRIQHLER---EITRY 719
Query: 146 KRELARAQDDYISLDVQHTSSISGMKRESED---DPESEPDDHEKRIPFTLRPQTLRQR- 201
K E ++AQ + L ++ + K + + + E + D K++ + + ++
Sbjct: 720 KDESSKAQAEVDRL-LEILKEVENEKNDKDKKIAELERQVKDQNKKVANLKHKEQVEKKK 778
Query: 202 ---MAEESISRNEETSEESQE-----DEKQDTWEQ--QQMRKAVKIIEERDIDLSCG--- 248
M EE+ R + ++ SQ+ +K D E+ + +R++V+I ER++ L+
Sbjct: 779 SAQMLEEARRREDNLNDSSQQLQDSLRKKDDRIEELEEALRESVQITAEREMVLAQEESA 838
Query: 249 --NGSSKVKKFDTSISFPPVNLEIIKKQLNTRLTLL--QETHRSHLR-EYEKYVQDVKSS 303
N +V++ ++ LE +K +L++ L +ETH ++LR E K++++V
Sbjct: 839 RTNAEKQVEELLMAMEKVKQELESMKAKLSSTQQSLAEKETHLTNLRAERRKHLEEVLEM 898
Query: 304 KSTIQNLESSSNQALNCKFYKSMKIYVENLIDCLNEKIINIQEIESSMHALLLKQAMTFM 363
K E L+ ++EK NI +E S ++ + +
Sbjct: 899 KQ-------------------------EALLAAISEKDANIALLELSSSKKKTQEEVAAL 933
Query: 364 KRRQDELKHESTYLQQLSRKDE 385
KR +D L +QQL ++ +
Sbjct: 934 KREKDRL------VQQLKQQTQ 949
Score = 30.0 bits (66), Expect = 8.6
Identities = 26/98 (26%), Positives = 47/98 (47%), Gaps = 10/98 (10%)
Query: 519 LKEMPWFKSVEEFMDSSVEDSKKESSSDKKVLSAIINK--TIIPRLTD---FVEFLWDPL 573
+K+M ++S +FM + + K+E S L A+ K T+ + +D +E L + L
Sbjct: 423 MKQMEVYRSHSKFMKNKIGQVKQELSRKDTELLALQTKLETLTNQFSDSKQHIEVLKESL 482
Query: 574 STSQTTSLITH-----CRVILEEHSTCENEVSKSRQDL 606
+ + + I R+ LEE T N+ +K QD+
Sbjct: 483 TAKEQRAAILQTEVDALRLRLEEKETMLNKKTKQIQDM 520
>gi|121256621 dentin matrix acidic phosphoprotein 1 isoform 2
precursor [Homo sapiens]
Length = 497
Score = 42.7 bits (99), Expect = 0.001
Identities = 77/334 (23%), Positives = 132/334 (39%), Gaps = 44/334 (13%)
Query: 88 SESRTLDVSTDEEDKIHHSSESKDDQGLSSDSSSSLGEKELSSTVKIPDAAFIQAARRKR 147
SE + +D E H DD+G+ SD S+ + +S + ++
Sbjct: 173 SEEHWVGGGSDGESS-HGDGSELDDEGMQSDDPESIRSERGNSRMNSAGMKSKESGENS- 230
Query: 148 ELARAQDDYISLDVQHTS-SISGMKRESEDDPESEPDDHEKRIPFTLRPQTLRQRMAEES 206
E A QD S ++H S I R SE+D SE DD+ + ++ E S
Sbjct: 231 EQANTQDSGGSQLLEHPSRKIFRKSRISEEDDRSELDDNNTM-------EEVKSDSTENS 283
Query: 207 ISRNEETSE-------ESQEDEKQD-TWEQQQMRKAVKIIEERDIDLSCGNGSSKVKKFD 258
SR+ S+ +SQED K++ + E+ Q ++ +LS SS+ ++
Sbjct: 284 NSRDTGLSQPRRDSKGDSQEDSKENLSQEESQNVDGPSSESSQEANLSSQENSSESQEEV 343
Query: 259 TSISF---PPVNLEIIKKQLNTRLTLLQETHRSHLREYEKYVQDVKSSKSTIQNLESSSN 315
S S P ++ Q ++ + E SH + K S+S + +S S+
Sbjct: 344 VSESRGDNPDPTTSYVEDQEDSDSS---EEDSSHTLSHSK-------SESREEQADSESS 393
Query: 316 QALNCKFYKSMKIYVENLIDCLNEKIINIQEIESSMHALLLKQAMTFMKRRQDELKHEST 375
++LN + E + ++ + QE S + Q+ D +S+
Sbjct: 394 ESLN---------FSEESPESPEDENSSSQEGLQSHSSSAESQSEESHSEEDDSDSQDSS 444
Query: 376 YLQQLSRKDETSTSGNFSVDEKTQWILEEIESRR 409
S++D ST S +E Q EIESR+
Sbjct: 445 R----SKEDSNSTESKSSSEEDGQLKNIEIESRK 474
Score = 35.0 bits (79), Expect = 0.27
Identities = 50/238 (21%), Positives = 86/238 (36%), Gaps = 30/238 (12%)
Query: 21 GAEESPAEPGAPRELPVPGSAEEEPPS-----GGGRAQVAGLPHRVRGPR---------- 65
G + + G EL G ++P S G R AG+ + G
Sbjct: 180 GGSDGESSHGDGSELDDEGMQSDDPESIRSERGNSRMNSAGMKSKESGENSEQANTQDSG 239
Query: 66 GRGRVWASSRRATKAAPRADEGSESRTLDVSTDEEDKIHHSSESKD-DQGLSSDSSSSLG 124
G + SR+ + + ++E S D +T EE K + S D GLS S G
Sbjct: 240 GSQLLEHPSRKIFRKSRISEEDDRSELDDNNTMEEVKSDSTENSNSRDTGLSQPRRDSKG 299
Query: 125 E----------KELSSTVKIPDAAFIQAAR--RKRELARAQDDYISLDVQHTSSISGMKR 172
+ +E S V P + Q A + + +Q++ +S +
Sbjct: 300 DSQEDSKENLSQEESQNVDGPSSESSQEANLSSQENSSESQEEVVSESRGDNPDPTTSYV 359
Query: 173 ESEDDPESEPDDHEKRIPFTLRPQTLRQRMAEESISRNEETSEESQEDEKQDTWEQQQ 230
E ++D +S +D + + R+ A+ S + SEES E + + Q+
Sbjct: 360 EDQEDSDSSEEDSSHTLSHSKSES--REEQADSESSESLNFSEESPESPEDENSSSQE 415
>gi|209862789 microtubule associated monoxygenase, calponin and LIM
domain containing 3 isoform 1 [Homo sapiens]
Length = 2002
Score = 42.0 bits (97), Expect = 0.002
Identities = 46/189 (24%), Positives = 76/189 (40%), Gaps = 21/189 (11%)
Query: 5 PKRTFRQRAADSSDSDGAEESPAEPGAPRELPVPGSAEEE----PPSGGGRAQVAGLPHR 60
P+ T + S GAEE A + E+ G EEE PPS + G+P +
Sbjct: 910 PEETQAEHNLSSVLDTGAEEDVASSSSESEMEEEGEEEEEEPRLPPS-----DLGGVPWK 964
Query: 61 VRGPRGRGRVWASSRRATKAAPRADEGSESRTLDVSTDEEDKIHHSSESKDDQGLSSDSS 120
R + S +A+ G+E +EE++ + E ++D + S
Sbjct: 965 -EAVRIHALLKGKSEEELEASKSFGPGNEE-------EEEEEEEYEEEEEEDYDEEEEES 1016
Query: 121 SSLGEKELSSTVKIPDAAFIQAARRKRELARAQDDYISLDVQHTSSISGM---KRESEDD 177
S G + L + D IQA + R +++ + SS SG + + E+D
Sbjct: 1017 SEAGNQRLQQVMHAADPLEIQADVHWTHI-REREEEERMAPASESSASGAPLDENDLEED 1075
Query: 178 PESEPDDHE 186
+SEP + E
Sbjct: 1076 VDSEPAEIE 1084
Score = 30.4 bits (67), Expect = 6.6
Identities = 20/91 (21%), Positives = 40/91 (43%), Gaps = 19/91 (20%)
Query: 159 LDVQHTSSISGMKRESEDDPESEPDDHEKRIP----------FTLRPQTLRQRMAEESI- 207
LD ++ ESE + E E ++ E R+P +R L + +EE +
Sbjct: 923 LDTGAEEDVASSSSESEMEEEGEEEEEEPRLPPSDLGGVPWKEAVRIHALLKGKSEEELE 982
Query: 208 --------SRNEETSEESQEDEKQDTWEQQQ 230
+ EE EE E+E+++ +++++
Sbjct: 983 ASKSFGPGNEEEEEEEEEYEEEEEEDYDEEE 1013
>gi|22758136 MAP7 domain containing 2 [Homo sapiens]
Length = 732
Score = 42.0 bits (97), Expect = 0.002
Identities = 49/231 (21%), Positives = 99/231 (42%), Gaps = 39/231 (16%)
Query: 26 PAEPGAPRELPVPGSAEEEPPSGGGRAQVAGLPHRVRGPRGRGRVWASSRRATKAAPRAD 85
P PG+P + +P + ++ P + + + R +++A A P+ +
Sbjct: 310 PPYPGSPVKYRLPALSGQDMPKRKAEKEKSN----------KEREGTLAQQA--AGPQGE 357
Query: 86 EGSESRTLDVSTDEEDKIHHSSESKDDQGLSSDSSSSLGEKELSSTVKIPDAAFIQAARR 145
E E +D E+ H++ + G +++S++LG K + T +AA I A +R
Sbjct: 358 EALEKHVVDKHASEK----HAAAA----GGKAENSAALG-KPTAGTTDAGEAAKILAEKR 408
Query: 146 KRELARAQDDYISLDVQHTSSISGMKRESEDDPESEPDDHEKRIPFTLRPQTLRQRMAEE 205
++ AR Q + +E ++ E E D +R + + R R+ EE
Sbjct: 409 RQ--ARLQKE----------------QEEQERVEKEEQDRLEREELKRKAEEERLRLEEE 450
Query: 206 SISRNEETSEESQEDEKQDTWEQQQMRKAVKIIEERDIDLSCGNGSSKVKK 256
+ + EE + +E +KQ+ E+++ + K E ++ L K +K
Sbjct: 451 ARKQEEERKRQEEEKKKQEGEEKRKAGEEAKRKAEEELLLKEKQEQEKQEK 501
>gi|55770834 centromere protein F [Homo sapiens]
Length = 3114
Score = 41.6 bits (96), Expect = 0.003
Identities = 73/365 (20%), Positives = 146/365 (40%), Gaps = 62/365 (16%)
Query: 227 EQQQMRKAVKIIEERDIDLSCGNGSSKVKKFDTSISFPPVNLEIIKKQLNTRLTLLQETH 286
E Q K I++ R L S K + ++ + L IK ++ L ++ H
Sbjct: 817 EADQSPKNSAILQNRVDSLEFSLESQK--QMNSDLQKQCEELVQIKGEIEENLMKAEQMH 874
Query: 287 RSHLREYEKYVQDVKSSKSTIQNLESSSNQALNCKFYKSMKIYVENLIDCLNEKI----I 342
+S + E + + ++ S QN+ + + AL K E + LN+K+
Sbjct: 875 QSFVAETSQRISKLQEDTSAHQNVVAETLSALENK---------EKELQLLNDKVETEQA 925
Query: 343 NIQEIESSMHAL--------LLKQAMTFMKRRQDE-LKHESTYLQQLSRKDETSTSGNFS 393
IQE++ S H L LL + ++ K+ + +++L++++ T N S
Sbjct: 926 EIQELKKSNHLLEDSLKELQLLSETLSLEKKEMSSIISLNKREIEELTQENGTLKEINAS 985
Query: 394 VDEKTQWILEEIESRRTKRRQARVLSGNCNHQEGTSSD--DELPSAEMIDFQKSQ----- 446
++++ ++++ ES + + +E + S+ D+ ++I Q+ +
Sbjct: 986 LNQEKMNLIQKSES----------FANYIDEREKSISELSDQYKQEKLILLQRCEETGNA 1035
Query: 447 -GDILQKQKKVFEEVQDDFCNI-------QNILLKFQQWREKFPDSYYEAFISLCIPKLL 498
D+ QK K E+ C + +N + +Q +E F + E L +
Sbjct: 1036 YEDLSQKYKAAQEKNSKLECLLNECTSLCENRKNELEQLKEAFAKEHQEFLTKLAFAEER 1095
Query: 499 NPLIRVQL------------IDWNPLKLESTGLK-EMPWFKSVEEFMDSSVEDSKKESSS 545
N + ++L + N K E+ GLK E+ K + M V D +E+
Sbjct: 1096 NQNLMLELETVQQALRSEMTDNQNNSKSEAGGLKQEIMTLKEEQNKMQKEVNDLLQENEQ 1155
Query: 546 DKKVL 550
KV+
Sbjct: 1156 LMKVM 1160
>gi|148596984 golgi autoantigen, golgin subfamily b, macrogolgin (with
transmembrane signal), 1 [Homo sapiens]
Length = 3259
Score = 41.6 bits (96), Expect = 0.003
Identities = 116/559 (20%), Positives = 218/559 (38%), Gaps = 108/559 (19%)
Query: 88 SESRTLDVSTDEEDKIHHSSESKD-----DQGLSSDSSSSLGEKELSSTVKIPDAAFIQA 142
+E +L E+ H S + + D G+ S+ G+K LS+ +PD
Sbjct: 627 NEESSLPAVEKEQASTEHQSRTSEEISLNDAGVELKSTKQDGDKSLSA---VPDIGQCH- 682
Query: 143 ARRKRELARAQDDYISLDVQHTSSISGMKRESEDDPESEPDDHEKRIPFTLRPQTLRQRM 202
+ EL R + + L++ ++++ E D+ K I L Q +
Sbjct: 683 ---QDELERLKSQILELELNF--------HKAQEIYEKNLDEKAKEI------SNLNQLI 725
Query: 203 AEESISRNEETSEESQEDEKQDTWEQQ--------QMRKAVKIIE------ERDIDLSCG 248
E + + +S + E++D Q ++R VK +E ER L
Sbjct: 726 EEFKKNADNNSSAFTALSEERDQLLSQVKELSMVTELRAQVKQLEMNLAEAERQRRLDYE 785
Query: 249 NGSSKVKKFDTSISFPPVNLEIIKKQLNTRLTLLQETHRSHLREYEKYVQDVKSSKSTIQ 308
+ ++ D ++ +L I K + ++ +LQ ++ + ++S +S +Q
Sbjct: 786 SQTAH----DNLLTEQIHSLSIEAKSKDVKIEVLQNELDDVQLQFSEQSTLIRSLQSQLQ 841
Query: 309 NLESSSNQALNCKFYKSMKIYVENLIDCLNEKIINIQEIESSMHALLLKQAMTFMKRRQD 368
N ES + + S K VE L L++K + I + M LLL+ K+R
Sbjct: 842 NKESEVLEGAERVRHISSK--VEELSQALSQKELEI----TKMDQLLLE------KKRDV 889
Query: 369 ELKHESTYLQQLSRKDETSTSGNFSVDEKTQWILEEIESR----RTKRRQARVLS-GNCN 423
E T Q + KD+ T +FS+ EK + EE S +T + Q +LS
Sbjct: 890 E-----TLQQTIEEKDQQVTEISFSMTEKMVQLNEEKFSLGVEIKTLKEQLNLLSRAEEA 944
Query: 424 HQEGTSSDDELPSA--EMIDFQKSQGDILQKQKKVFEEVQDDFCNIQNILLKFQQWREKF 481
+E D+E+ S + D G I + EE+Q +F ++L K + R++
Sbjct: 945 KKEQVEEDNEVSSGLKQNYDEMSPAGQISK------EELQHEF----DLLKKENEQRKR- 993
Query: 482 PDSYYEAFISLCIPKLLNPLIRVQLIDWNPLKLESTGLKEMPWFKSVEEFMDSSVEDSKK 541
+ + L RV ++ L+ KE+P + E VE+ K+
Sbjct: 994 -------KLQAALINRKELLQRVSRLEEELANLKDESKKEIP----LSETERGEVEEDKE 1042
Query: 542 ESSSDKKVLSAIINKTIIPRLTDFVEFLWDPLSTSQTTSLITHCRVILEEHSTCENEVSK 601
+K +++ + + +L +S + + H R LEE E +
Sbjct: 1043 NKEYSEKCVTS--------KCQEIEIYLKQTISEKEVE--LQHIRKDLEEKLAAEEQ--- 1089
Query: 602 SRQDLLKSIVSRMKKAVED 620
+++V +M + ++D
Sbjct: 1090 -----FQALVKQMNQTLQD 1103
Database: hs.faa
Posted date: Aug 4, 2009 4:42 PM
Number of letters in database: 18,247,518
Number of sequences in database: 37,866
Lambda K H
0.313 0.129 0.361
Gapped
Lambda K H
0.267 0.0410 0.140
Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Hits to DB: 29,046,984
Number of Sequences: 37866
Number of extensions: 1370093
Number of successful extensions: 9021
Number of sequences better than 10.0: 30
Number of HSP's better than 10.0 without gapping: 54
Number of HSP's successfully gapped in prelim test: 617
Number of HSP's that attempted gapping in prelim test: 7690
Number of HSP's gapped (non-prelim): 1818
length of query: 781
length of database: 18,247,518
effective HSP length: 110
effective length of query: 671
effective length of database: 14,082,258
effective search space: 9449195118
effective search space used: 9449195118
T: 11
A: 40
X1: 16 ( 7.2 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 42 (21.9 bits)
S2: 66 (30.0 bits)
Search results were obtained with NCBI BLAST and RefSeq entries.
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Guide to the Human Genome
Copyright © 2010 by Stewart Scherer. All rights reserved.